locus-tag	class	description
FE240_RS00015	COG0129	dihydroxy-acid dehydratase activity
FE240_RS00025	COG3978	acetolactate synthase activity
FE240_RS00035	COG0606	chelatase, subunit chli
FE240_RS00040	COG0204	Acyl-transferase
FE240_RS00045	COG0204	Acyl-transferase
FE240_RS00050	COG1683	Conserved Protein
FE240_RS00060	COG1335	isochorismatase
FE240_RS00070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FE240_RS00075	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FE240_RS00085	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FE240_RS00095	COG0514	ATP-dependent DNA helicase (RecQ)
FE240_RS00100	COG2050	protein possibly involved in aromatic compounds catabolism
FE240_RS00115	COG2959	enzyme of heme biosynthesis
FE240_RS00125	COG0181	hydroxymethylbilane synthase activity
FE240_RS00130	COG3072	Adenylate cyclase
FE240_RS00140	COG1965	Belongs to the frataxin family
FE240_RS00150	COG0019	diaminopimelate decarboxylase activity
FE240_RS00155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FE240_RS00165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FE240_RS00170	COG1011	Hydrolase
FE240_RS00175	COG2204	response regulator
FE240_RS00180	COG3852	Histidine kinase
FE240_RS00190	COG0174	glutamine synthetase
FE240_RS00195	COG1217	gtp-binding protein TYPA
FE240_RS00200	COG1295	ribonuclease BN
FE240_RS00205	COG2267	carboxylic ester hydrolase activity
FE240_RS00210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE240_RS00215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE240_RS00220	COG1758	RNA polymerase activity
FE240_RS00230	COG0859	PFAM glycosyl transferase family 9
FE240_RS00235	COG3642	lipopolysaccharide core region biosynthetic process
FE240_RS00275	COG0589	response to stress
FE240_RS00280	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FE240_RS00285	COG1528	Iron-storage protein
FE240_RS00290	COG2081	HI0933 family
FE240_RS00310	COG3188	usher protein
FE240_RS00330	COG2205	protein histidine kinase activity
FE240_RS00330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_RS00340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FE240_RS00345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FE240_RS00390	COG0166	Belongs to the GPI family
FE240_RS00400	COG0789	Transcriptional regulator
FE240_RS00405	COG3706	GGDEF domain
FE240_RS00405	COG4251	negative regulation of phosphorylation
FE240_RS00405	COG2203	Gaf domain
FE240_RS00405	COG5001	Diguanylate cyclase
FE240_RS00410	COG3084	Protein conserved in bacteria
FE240_RS00420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FE240_RS00425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE240_RS00430	COG2183	response to ionizing radiation
FE240_RS00435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE240_RS00450	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FE240_RS00455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FE240_RS00465	COG3031	protein transport across the cell outer membrane
FE240_RS00470	COG1450	Type ii and iii secretion system protein
FE240_RS00475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FE240_RS00480	COG1459	type II secretion system
FE240_RS00485	COG2165	general secretion pathway protein
FE240_RS00495	COG2165	general secretion pathway protein
FE240_RS00500	COG4795	General secretion pathway protein
FE240_RS00505	COG3156	type II secretion system protein K
FE240_RS00515	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FE240_RS00525	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FE240_RS00530	COG4208	sulfate ABC transporter
FE240_RS00535	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FE240_RS00540	COG0583	DNA-binding transcription factor activity
FE240_RS00560	COG4221	oxidoreductase activity
FE240_RS00565	COG1979	alcohol dehydrogenase
FE240_RS00575	COG2873	o-acetylhomoserine
FE240_RS00585	COG4533	DNA binding
FE240_RS00600	COG0596	Alpha beta hydrolase
FE240_RS00610	COG0316	Belongs to the HesB IscA family
FE240_RS00610	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FE240_RS00615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FE240_RS00620	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FE240_RS00625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FE240_RS00630	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FE240_RS00635	COG4942	peptidase
FE240_RS00640	COG0004	ammonium transporteR
FE240_RS00645	COG1609	Transcriptional regulator
FE240_RS00650	COG0800	Aldolase
FE240_RS00655	COG0129	dihydroxy-acid dehydratase activity
FE240_RS00660	COG3265	gluconokinase activity
FE240_RS00665	COG2610	gluconate transmembrane transporter activity
FE240_RS00670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE240_RS00675	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FE240_RS00685	COG0456	acetyltransferase
FE240_RS00690	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FE240_RS00695	COG1490	D-aminoacyl-tRNA deacylase activity
FE240_RS00700	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FE240_RS00715	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FE240_RS00720	COG1079	Belongs to the binding-protein-dependent transport system permease family
FE240_RS00725	COG4603	Belongs to the binding-protein-dependent transport system permease family
FE240_RS00730	COG3845	ABC transporter
FE240_RS00735	COG1744	ABC transporter substrate-binding protein PnrA-like
FE240_RS00740	COG0110	maltose O-acetyltransferase activity
FE240_RS00745	COG3174	membrane
FE240_RS00750	COG0642	Histidine kinase
FE240_RS00755	COG0745	RESPONSE REGULATOR receiver
FE240_RS00770	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FE240_RS00775	COG0352	thiamine-phosphate diphosphorylase activity
FE240_RS00780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FE240_RS00790	COG2022	thiamine diphosphate biosynthetic process
FE240_RS00795	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FE240_RS00835	COG0583	DNA-binding transcription factor activity
FE240_RS00845	COG1741	Belongs to the pirin family
FE240_RS00850	COG2259	Doxx family
FE240_RS00855	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FE240_RS00860	COG1074	ATP-dependent DNA helicase activity
FE240_RS00865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE240_RS00870	COG0513	Belongs to the DEAD box helicase family
FE240_RS00875	COG0523	cobalamin synthesis protein
FE240_RS00880	COG2879	small protein
FE240_RS00885	COG1966	Carbon starvation protein
FE240_RS00900	COG2070	2-Nitropropane dioxygenase
FE240_RS00905	COG0494	nUDIX hydrolase
FE240_RS00935	COG2321	neutral zinc metallopeptidase
FE240_RS00940	COG3681	Belongs to the UPF0597 family
FE240_RS00950	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE240_RS00955	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE240_RS00960	COG0564	pseudouridine synthase activity
FE240_RS00965	COG2233	PERMEase
FE240_RS00970	COG0151	Belongs to the GarS family
FE240_RS00975	COG0138	bifunctional purine biosynthesis protein purh
FE240_RS00980	COG0789	Transcriptional regulator
FE240_RS00990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FE240_RS00995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FE240_RS01000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FE240_RS01010	COG0673	inositol 2-dehydrogenase activity
FE240_RS01035	COG0477	Major facilitator Superfamily
FE240_RS01040	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FE240_RS01045	COG1027	Aspartate ammonia-lyase
FE240_RS01055	COG0534	Mate efflux family protein
FE240_RS01060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FE240_RS01065	COG0459	protein refolding
FE240_RS01095	COG0564	pseudouridine synthase activity
FE240_RS01100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FE240_RS01130	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FE240_RS01135	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FE240_RS01140	COG1178	ABC-type Fe3 transport system permease component
FE240_RS01145	COG4143	(ABC) transporter
FE240_RS01160	COG0066	3-isopropylmalate dehydratase activity
FE240_RS01165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FE240_RS01175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FE240_RS01195	COG0028	Belongs to the TPP enzyme family
FE240_RS01200	COG0440	acetolactate synthase activity
FE240_RS01205	COG2200	EAL domain
FE240_RS01210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE240_RS01220	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FE240_RS01225	COG3171	Protein conserved in bacteria
FE240_RS01230	COG2066	Belongs to the glutaminase family
FE240_RS01235	COG2897	thiosulfate sulfurtransferase activity
FE240_RS01240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FE240_RS01260	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FE240_RS01265	COG5001	Diguanylate cyclase
FE240_RS01285	COG4628	conserved protein (DUF2132)
FE240_RS01290	COG0688	phosphatidylethanolamine metabolic process
FE240_RS01295	COG1162	GTPase activity
FE240_RS01300	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FE240_RS01355	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FE240_RS01355	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FE240_RS01360	COG0802	atpase or kinase
FE240_RS01370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FE240_RS01375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FE240_RS01380	COG1923	regulation of RNA biosynthetic process
FE240_RS01385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FE240_RS01390	COG0330	HflC and HflK could
FE240_RS01395	COG0330	HflC and HflK could
FE240_RS01400	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FE240_RS01405	COG0142	geranyltranstransferase activity
FE240_RS01410	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FE240_RS01415	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FE240_RS01420	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FE240_RS01425	COG2966	Psort location CytoplasmicMembrane, score
FE240_RS01430	COG3610	response to peptide
FE240_RS01440	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FE240_RS01445	COG2967	ApaG domain
FE240_RS01450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FE240_RS01455	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FE240_RS01465	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FE240_RS01470	COG3178	'Phosphotransferase
FE240_RS01475	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FE240_RS01480	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FE240_RS01485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FE240_RS01495	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FE240_RS01505	COG0516	GMP reductase activity
FE240_RS01510	COG0835	chemotaxis
FE240_RS01510	COG0784	Response regulator, receiver
FE240_RS01515	COG1444	tRNA N-acetyltransferase activity
FE240_RS01555	COG1686	Belongs to the peptidase S11 family
FE240_RS01565	COG1253	flavin adenine dinucleotide binding
FE240_RS01570	COG0525	valine-tRNA ligase activity
FE240_RS01580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FE240_RS01585	COG0795	lipopolysaccharide-transporting ATPase activity
FE240_RS01590	COG0795	lipopolysaccharide-transporting ATPase activity
FE240_RS01605	COG0582	viral genome integration into host DNA
FE240_RS01655	COG0004	ammonium transporteR
FE240_RS01660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FE240_RS01665	COG0084	hydrolase, TatD family'
FE240_RS01670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FE240_RS01680	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FE240_RS01685	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FE240_RS01690	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FE240_RS01695	COG0813	purine-nucleoside phosphorylase activity
FE240_RS01710	COG0560	Phosphoserine phosphatase
FE240_RS01730	COG1757	Na H antiporter
FE240_RS01770	COG0297	glycogen (starch) synthase activity
FE240_RS01775	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FE240_RS01780	COG2813	Specifically methylates the guanine in position
FE240_RS01785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE240_RS01795	COG2995	paraquat-inducible protein a
FE240_RS01800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FE240_RS01800	COG3008	intermembrane lipid transfer
FE240_RS01815	COG0741	lytic transglycosylase activity
FE240_RS01820	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FE240_RS01825	COG1194	a g-specific adenine glycosylase
FE240_RS01835	COG3409	Peptidoglycan-binding domain 1 protein
FE240_RS01835	COG3267	Type II secretory pathway component ExeA
FE240_RS01840	COG0617	tRNA 3'-terminal CCA addition
FE240_RS01845	COG0306	phosphate transporter
FE240_RS01850	COG1392	Phosphate transport regulator
FE240_RS01860	COG1560	Kdo2-lipid A biosynthetic process
FE240_RS01865	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FE240_RS01865	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FE240_RS01870	COG2827	Endonuclease containing a URI domain
FE240_RS01875	COG2962	Rard protein
FE240_RS01880	COG1573	uracil-dna glycosylase
FE240_RS01890	COG0583	DNA-binding transcription factor activity
FE240_RS01895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FE240_RS01900	COG1121	(ABC) transporter
FE240_RS01905	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FE240_RS01915	COG2358	TRAP transporter, solute receptor (TAXI family
FE240_RS01925	COG0739	heme binding
FE240_RS01935	COG0604	alcohol dehydrogenase
FE240_RS01940	COG1238	metal cluster binding
FE240_RS01945	COG0612	Peptidase, M16
FE240_RS01950	COG2918	glutathione biosynthetic process
FE240_RS01960	COG1022	Amp-dependent synthetase and ligase
FE240_RS01970	COG0456	acetyltransferase
FE240_RS01980	COG0714	Associated with various cellular activities
FE240_RS01985	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FE240_RS02010	COG1902	pentaerythritol trinitrate reductase activity
FE240_RS02025	COG2957	Belongs to the agmatine deiminase family
FE240_RS02030	COG0154	amidase activity
FE240_RS02065	COG0513	Belongs to the DEAD box helicase family
FE240_RS02075	COG0789	Transcriptional regulator
FE240_RS02095	COG0577	efflux transmembrane transporter activity
FE240_RS02095	COG1136	(ABC) transporter
FE240_RS02100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_RS02105	COG0745	RESPONSE REGULATOR receiver
FE240_RS02115	COG2814	Major facilitator Superfamily
FE240_RS02125	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FE240_RS02135	COG1335	isochorismatase
FE240_RS02140	COG0583	DNA-binding transcription factor activity
FE240_RS02145	COG0346	lactoylglutathione lyase activity
FE240_RS02150	COG2207	Transcriptional regulator
FE240_RS02180	COG2205	protein histidine kinase activity
FE240_RS02190	COG2204	response regulator
FE240_RS02200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FE240_RS02230	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FE240_RS02230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE240_RS02245	COG1854	S-ribosylhomocysteine lyase activity
FE240_RS02250	COG3706	GGDEF domain
FE240_RS02260	COG0557	exoribonuclease II activity
FE240_RS02265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE240_RS02275	COG2153	protein acetylation
FE240_RS02305	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FE240_RS02310	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FE240_RS02320	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FE240_RS02325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FE240_RS02335	COG0180	Tryptophanyl-tRNA synthetase
FE240_RS02350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FE240_RS02355	COG3138	arginine N-succinyltransferase
FE240_RS02360	COG1012	belongs to the aldehyde dehydrogenase family
FE240_RS02375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE240_RS02380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FE240_RS02385	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE240_RS02390	COG0175	sulfate reduction
FE240_RS02400	COG3706	GGDEF domain
FE240_RS02405	COG2113	Glycine betaine
FE240_RS02410	COG4176	ABC-type proline glycine betaine transport system permease component
FE240_RS02415	COG4175	Glycine betaine
FE240_RS02420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE240_RS02435	COG0523	cobalamin synthesis protein
FE240_RS02440	COG0477	Major facilitator Superfamily
FE240_RS02450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FE240_RS02455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FE240_RS02485	COG3314	Sporulation integral membrane protein YlbJ
FE240_RS02490	COG1280	lysine exporter protein (LysE YggA)
FE240_RS02500	COG2261	transglycosylase associated protein
FE240_RS02515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FE240_RS02520	COG1053	succinate dehydrogenase
FE240_RS02530	COG0584	glycerophosphoryl diester phosphodiesterase
FE240_RS02535	COG1511	domain protein
FE240_RS02535	COG3264	Mechanosensitive ion channel
FE240_RS02540	COG4942	peptidase
FE240_RS02555	COG0513	Belongs to the DEAD box helicase family
FE240_RS02560	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FE240_RS02580	COG0735	belongs to the Fur family
FE240_RS02585	COG1007	ATP synthesis coupled electron transport
FE240_RS02590	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE240_RS02600	COG0713	ATP synthesis coupled electron transport
FE240_RS02605	COG0839	Belongs to the complex I subunit 6 family
FE240_RS02610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE240_RS02615	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FE240_RS02620	COG1034	ATP synthesis coupled electron transport
FE240_RS02635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE240_RS02635	COG0649	NAD binding
FE240_RS02640	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE240_RS02645	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE240_RS02650	COG1360	Flagellar Motor Protein
FE240_RS02655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FE240_RS02670	COG0745	RESPONSE REGULATOR receiver
FE240_RS02675	COG3104	oligopeptide transport
FE240_RS02680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FE240_RS02685	COG1555	photosystem II stabilization
FE240_RS02690	COG1218	3'(2'),5'-bisphosphate nucleotidase
FE240_RS02695	COG2350	Protein conserved in bacteria
FE240_RS02700	COG2917	probably involved in intracellular septation
FE240_RS02705	COG0076	glutamate decarboxylase activity
FE240_RS02710	COG0569	domain protein
FE240_RS02710	COG2985	domain, Protein
FE240_RS02720	COG1278	Cold shock
FE240_RS02730	COG0840	transmembrane signaling receptor activity
FE240_RS02735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE240_RS02770	COG0835	chemotaxis
FE240_RS02770	COG0784	Response regulator, receiver
FE240_RS02780	COG4181	ATPase activity
FE240_RS02785	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FE240_RS02790	COG1090	epimerase
FE240_RS02795	COG0280	phosphate acetyltransferase
FE240_RS02795	COG0857	belongs to the CobB CobQ family
FE240_RS02800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FE240_RS02805	COG3092	negative regulation of chromosome organization
FE240_RS02810	COG3013	Belongs to the UPF0304 family
FE240_RS02815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FE240_RS02820	COG2716	regulation of RNA biosynthetic process
FE240_RS02830	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FE240_RS02835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FE240_RS02840	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FE240_RS02845	COG0142	geranyltranstransferase activity
FE240_RS02850	COG1722	exodeoxyribonuclease VII activity
FE240_RS02855	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FE240_RS02860	COG1360	Flagellar Motor Protein
FE240_RS02875	COG1534	Rna-binding protein
FE240_RS02880	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FE240_RS02885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FE240_RS02890	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FE240_RS02895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE240_RS02900	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FE240_RS02915	COG0779	Required for maturation of 30S ribosomal subunits
FE240_RS02920	COG0195	Participates in both transcription termination and antitermination
FE240_RS02925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FE240_RS02930	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FE240_RS02935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FE240_RS02940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FE240_RS02945	COG1185	polyribonucleotide nucleotidyltransferase activity
FE240_RS02950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE240_RS02955	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FE240_RS02970	COG0583	DNA-binding transcription factor activity
FE240_RS02990	COG0561	phosphatase activity
FE240_RS03005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE240_RS03020	COG1794	racemase activity, acting on amino acids and derivatives
FE240_RS03030	COG2731	YhcH YjgK YiaL family protein
FE240_RS03040	COG3545	Serine hydrolase
FE240_RS03045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FE240_RS03050	COG0321	lipoyl(octanoyl) transferase activity
FE240_RS03055	COG2921	Belongs to the UPF0250 family
FE240_RS03060	COG1686	Belongs to the peptidase S11 family
FE240_RS03065	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FE240_RS03070	COG0772	Belongs to the SEDS family
FE240_RS03075	COG0768	penicillin binding
FE240_RS03080	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FE240_RS03085	COG0799	negative regulation of ribosome biogenesis
FE240_RS03090	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FE240_RS03095	COG1466	dna polymerase III delta subunit
FE240_RS03100	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FE240_RS03105	COG0495	leucyl-tRNA aminoacylation
FE240_RS03115	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FE240_RS03120	COG4535	Mg2 and Co2 transporter CorC
FE240_RS03125	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FE240_RS03130	COG1702	phosphate starvation-inducible protein PhoH
FE240_RS03135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE240_RS03140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE240_RS03145	COG1803	Methylglyoxal synthase
FE240_RS03155	COG0252	asparaginase activity
FE240_RS03175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE240_RS03175	COG1263	PTS System
FE240_RS03180	COG0366	Alpha amylase catalytic
FE240_RS03185	COG0110	maltose O-acetyltransferase activity
FE240_RS03210	COG0531	amino acid
FE240_RS03215	COG0366	Alpha amylase catalytic
FE240_RS03230	COG0463	Glycosyl transferase, family 2
FE240_RS03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_RS03245	COG2989	Protein conserved in bacteria
FE240_RS03250	COG3108	Peptidase M15
FE240_RS03260	COG2860	membrane
FE240_RS03270	COG1196	nuclear chromosome segregation
FE240_RS03275	COG3115	cell septum assembly
FE240_RS03280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FE240_RS03290	COG1328	CTP reductase activity
FE240_RS03295	COG0602	queuosine metabolic process
FE240_RS03300	COG2195	Cleaves the N-terminal amino acid of tripeptides
FE240_RS03305	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FE240_RS03310	COG1073	alpha beta
FE240_RS03325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FE240_RS03335	COG0589	response to stress
FE240_RS03350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE240_RS03355	COG2313	pseudouridylate synthase activity
FE240_RS03365	COG0521	Mo-molybdopterin cofactor biosynthetic process
FE240_RS03375	COG2252	PERMEase
FE240_RS03385	COG0488	(ABC) transporter
FE240_RS03390	COG0741	lytic transglycosylase activity
FE240_RS03395	COG0463	Glycosyl transferase, family 2
FE240_RS03425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE240_RS03430	COG4558	Periplasmic binding protein
FE240_RS03435	COG3721	Heme iron utilization protein
FE240_RS03440	COG0748	coenzyme F420 binding
FE240_RS03450	COG4638	Rieske (2fe-2S)
FE240_RS03455	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FE240_RS03460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE240_RS03460	COG0543	2 iron, 2 sulfur cluster binding
FE240_RS03525	COG2814	Major facilitator Superfamily
FE240_RS03530	COG2205	protein histidine kinase activity
FE240_RS03540	COG0442	prolyl-tRNA aminoacylation
FE240_RS03550	COG0632	four-way junction helicase activity
FE240_RS03555	COG2255	four-way junction helicase activity
FE240_RS03560	COG1271	oxidase subunit
FE240_RS03565	COG1294	oxidase, subunit
FE240_RS03570	COG4890	Cyd operon protein YbgT
FE240_RS03580	COG0824	Thioesterase
FE240_RS03585	COG0811	peptide transport
FE240_RS03595	COG3064	Membrane
FE240_RS03600	COG0823	Involved in the tonB-independent uptake of proteins
FE240_RS03605	COG2885	chlorophyll binding
FE240_RS03610	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FE240_RS03680	COG0840	transmembrane signaling receptor activity
FE240_RS03685	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FE240_RS03695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FE240_RS03700	COG1640	4-alpha-glucanotransferase
FE240_RS03705	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FE240_RS03730	COG3139	Protein of unknown function (DUF1315)
FE240_RS03735	COG0252	asparaginase activity
FE240_RS03740	COG0786	glutamate:sodium symporter activity
FE240_RS03745	COG0616	signal peptide processing
FE240_RS03750	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE240_RS03750	COG1902	pentaerythritol trinitrate reductase activity
FE240_RS03755	COG0778	Nitroreductase
FE240_RS03760	COG1522	sequence-specific DNA binding
FE240_RS03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE240_RS03775	COG1946	Acyl-CoA thioesterase
FE240_RS03790	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FE240_RS03795	COG0038	chloride channel
FE240_RS03805	COG0316	Belongs to the HesB IscA family
FE240_RS03850	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FE240_RS03865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_RS03885	COG2264	protein methyltransferase activity
FE240_RS03890	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FE240_RS03895	COG1489	DNA binding
FE240_RS03900	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FE240_RS03905	COG1643	Atp-dependent helicase
FE240_RS03910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE240_RS03915	COG0346	lactoylglutathione lyase activity
FE240_RS03925	COG0671	phosphoesterase, PA-phosphatase related
FE240_RS03945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE240_RS03950	COG0826	peptidase U32
FE240_RS03955	COG2200	EAL domain
FE240_RS03955	COG2199	diguanylate cyclase activity
FE240_RS03955	COG2203	Gaf domain
FE240_RS03960	COG1283	sodium-dependent phosphate transmembrane transporter activity
FE240_RS03970	COG0531	amino acid
FE240_RS03975	COG0531	amino acid
FE240_RS03985	COG1012	belongs to the aldehyde dehydrogenase family
FE240_RS03990	COG0174	glutamine synthetase
FE240_RS03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE240_RS04000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE240_RS04000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_RS04000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE240_RS04005	COG0405	Gamma-glutamyltransferase
FE240_RS04015	COG2207	Transcriptional regulator
FE240_RS04025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE240_RS04045	COG2916	Histone family protein nucleoid-structuring protein H-NS
FE240_RS04050	COG1196	nuclear chromosome segregation
FE240_RS04050	COG3264	Mechanosensitive ion channel
FE240_RS04055	COG2190	(PTS) system
FE240_RS04065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_RS04080	COG1720	tRNA m6t6A37 methyltransferase activity
FE240_RS04095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FE240_RS04100	COG4988	ABC transporter
FE240_RS04115	COG0745	RESPONSE REGULATOR receiver
FE240_RS04125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FE240_RS04135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE240_RS04145	COG2202	Pas domain
FE240_RS04145	COG2199	diguanylate cyclase activity
FE240_RS04145	COG2200	EAL domain
FE240_RS04155	COG3381	protein complex oligomerization
FE240_RS04170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FE240_RS04175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FE240_RS04180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE240_RS04180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE240_RS04195	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FE240_RS04200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FE240_RS04205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FE240_RS04210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FE240_RS04220	COG0747	negative chemotaxis
FE240_RS04225	COG0601	transmembrane transport
FE240_RS04230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE240_RS04255	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FE240_RS04260	COG0739	heme binding
FE240_RS04265	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FE240_RS04300	COG0791	NLP P60 protein
FE240_RS04310	COG1309	transcriptional regulator
FE240_RS04315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_RS04320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE240_RS04330	COG1482	cell wall glycoprotein biosynthetic process
FE240_RS04340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FE240_RS04350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FE240_RS04355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FE240_RS04360	COG2723	6-phospho-beta-galactosidase activity
FE240_RS04365	COG1447	Phosphotransferase system cellobiose-specific component IIA
FE240_RS04370	COG1940	carbohydrate kinase activity
FE240_RS04375	COG4580	involved in the transport of maltose and maltodextrins
FE240_RS04395	COG1609	Transcriptional regulator
FE240_RS04405	COG0159	tryptophan synthase activity
FE240_RS04410	COG0133	tryptophan synthase activity
FE240_RS04415	COG0135	phosphoribosylanthranilate isomerase activity
FE240_RS04415	COG0134	indole-3-glycerol-phosphate synthase activity
FE240_RS04420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FE240_RS04425	COG0512	Glutamine amidotransferase of anthranilate synthase
FE240_RS04425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FE240_RS04430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FE240_RS04435	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FE240_RS04440	COG0613	PHP domain protein
FE240_RS04445	COG0009	L-threonylcarbamoyladenylate synthase
FE240_RS04455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FE240_RS04485	COG0668	transmembrane transport
FE240_RS04490	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FE240_RS04500	COG0488	(ABC) transporter
FE240_RS04515	COG0330	HflC and HflK could
FE240_RS04520	COG0243	molybdopterin cofactor binding
FE240_RS04530	COG1116	anion transmembrane transporter activity
FE240_RS04530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FE240_RS04535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE240_RS04540	COG1116	anion transmembrane transporter activity
FE240_RS04545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE240_RS04545	COG2146	nitrite reductase [NAD(P)H] activity
FE240_RS04550	COG2146	nitrite reductase [NAD(P)H] activity
FE240_RS04550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE240_RS04555	COG1648	precorrin-2 dehydrogenase activity
FE240_RS04555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE240_RS04560	COG0175	sulfate reduction
FE240_RS04565	COG2895	sulfate adenylyltransferase (ATP) activity
FE240_RS04570	COG3273	potassium ion transport
FE240_RS04570	COG0471	metal ion transport
FE240_RS04575	COG0529	Catalyzes the synthesis of activated sulfate
FE240_RS04600	COG3550	peptidyl-serine autophosphorylation
FE240_RS04605	COG1396	sequence-specific DNA binding
FE240_RS04610	COG1560	Kdo2-lipid A biosynthetic process
FE240_RS04630	COG1136	(ABC) transporter
FE240_RS04645	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FE240_RS04660	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FE240_RS04665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE240_RS04670	COG0163	prenyltransferase activity
FE240_RS04685	COG1131	(ABC) transporter
FE240_RS04690	COG0842	Transport permease protein
FE240_RS04695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FE240_RS04700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FE240_RS04705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FE240_RS04715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE240_RS04720	COG1263	PTS System
FE240_RS04720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE240_RS04720	COG2190	(PTS) system
FE240_RS04725	COG4145	pantothenate transmembrane transporter activity
FE240_RS04735	COG0439	Biotin carboxylase
FE240_RS04740	COG0511	ligase activity, forming carbon-carbon bonds
FE240_RS04745	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FE240_RS04755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FE240_RS04760	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FE240_RS04765	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FE240_RS04775	COG0083	homoserine kinase activity
FE240_RS04780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FE240_RS04790	COG1846	Transcriptional regulator
FE240_RS04795	COG2205	protein histidine kinase activity
FE240_RS04795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_RS04810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE240_RS04815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_RS04820	COG0745	RESPONSE REGULATOR receiver
FE240_RS04825	COG5002	protein histidine kinase activity
FE240_RS04825	COG5000	phosphorelay sensor kinase activity
FE240_RS04840	COG1447	Phosphotransferase system cellobiose-specific component IIA
FE240_RS04845	COG2723	6-phospho-beta-galactosidase activity
FE240_RS04855	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FE240_RS04860	COG2273	Hydrolase Family 16
FE240_RS04860	COG5297	Belongs to the glycosyl hydrolase family 6
FE240_RS04865	COG1472	Belongs to the glycosyl hydrolase 3 family
FE240_RS04870	COG2182	Extracellular solute-binding protein
FE240_RS04875	COG1609	Transcriptional regulator
FE240_RS04895	COG0659	secondary active sulfate transmembrane transporter activity
FE240_RS04910	COG2271	Major facilitator Superfamily
FE240_RS04925	COG0625	glutathione transferase activity
FE240_RS04930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE240_RS04940	COG0840	transmembrane signaling receptor activity
FE240_RS04945	COG5492	domain, Protein
FE240_RS04945	COG4932	domain protein
FE240_RS04960	COG0702	epimerase
FE240_RS04965	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE240_RS04970	COG1454	alcohol dehydrogenase
FE240_RS04990	COG0497	DNA recombination
FE240_RS04995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FE240_RS05000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FE240_RS05005	COG0443	Heat shock 70 kDa protein
FE240_RS05010	COG0484	heat shock protein binding
FE240_RS05040	COG1285	pathogenesis
FE240_RS05085	COG0095	Lipoate-protein ligase
FE240_RS05100	COG2207	Transcriptional regulator
FE240_RS05105	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FE240_RS05110	COG0673	inositol 2-dehydrogenase activity
FE240_RS05115	COG3384	dioxygenase
FE240_RS05140	COG0788	formyltetrahydrofolate deformylase activity
FE240_RS05145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FE240_RS05155	COG3118	belongs to the thioredoxin family
FE240_RS05165	COG0791	NLP P60 protein
FE240_RS05170	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FE240_RS05190	COG0746	molybdenum cofactor guanylyltransferase activity
FE240_RS05195	COG1116	anion transmembrane transporter activity
FE240_RS05200	COG4662	Binding-protein-dependent transport system inner membrane component
FE240_RS05215	COG3852	Histidine kinase
FE240_RS05225	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FE240_RS05255	COG3383	formate dehydrogenase (NAD+) activity
FE240_RS05255	COG3383	formate dehydrogenase (NAD+) activity
FE240_RS05260	COG0437	4 iron, 4 sulfur cluster binding
FE240_RS05290	COG1881	PFAM PEBP family protein
FE240_RS05295	COG0708	Exodeoxyribonuclease III
FE240_RS05335	COG1280	lysine exporter protein (LysE YggA)
FE240_RS05345	COG3263	regulation of cellular component size
FE240_RS05355	COG1876	peptidase activity
FE240_RS05360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE240_RS05365	COG1393	Belongs to the ArsC family
FE240_RS05370	COG0105	UTP biosynthetic process
FE240_RS05375	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FE240_RS05390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FE240_RS05395	COG0124	histidyl-tRNA synthetase
FE240_RS05400	COG2976	Protein conserved in bacteria
FE240_RS05405	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE240_RS05410	COG1160	GTP binding
FE240_RS05415	COG1645	bacterial-type flagellum-dependent swarming motility
FE240_RS05425	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FE240_RS05440	COG0436	Aminotransferase
FE240_RS05450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FE240_RS05455	COG2027	D-alanyl-D-alanine carboxypeptidase
FE240_RS05460	COG1061	Type III restriction enzyme res subunit
FE240_RS05465	COG1566	PFAM secretion protein HlyD family protein
FE240_RS05475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FE240_RS05505	COG0590	tRNA wobble adenosine to inosine editing
FE240_RS05510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FE240_RS05540	COG0716	FMN binding
FE240_RS05555	COG0596	Alpha beta hydrolase
FE240_RS05560	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FE240_RS05565	COG0033	Phosphoglucomutase
FE240_RS05575	COG4574	serine-type endopeptidase inhibitor activity
FE240_RS05600	COG1187	pseudouridine synthase activity
FE240_RS05610	COG4166	transmembrane transport
FE240_RS05615	COG0622	Phosphoesterase
FE240_RS05635	COG0784	Response regulator, receiver
FE240_RS05635	COG0835	chemotaxis
FE240_RS05640	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FE240_RS05645	COG1815	bacterial-type flagellum-dependent cell motility
FE240_RS05665	COG4787	bacterial-type flagellum-dependent cell motility
FE240_RS05670	COG4786	Flagellar basal body rod
FE240_RS05675	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FE240_RS05680	COG1706	bacterial-type flagellum-dependent cell motility
FE240_RS05700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE240_RS05705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE240_RS05745	COG2089	acid synthase
FE240_RS05760	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FE240_RS05765	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FE240_RS05775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FE240_RS05780	COG1086	Polysaccharide biosynthesis protein
FE240_RS05785	COG2239	Acts as a magnesium transporter
FE240_RS05795	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FE240_RS05800	COG2716	regulation of RNA biosynthetic process
FE240_RS05810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FE240_RS05815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FE240_RS05820	COG1349	DNA-binding transcription factor activity
FE240_RS05825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FE240_RS05830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FE240_RS05835	COG0287	Prephenate dehydrogenase
FE240_RS05835	COG1605	Chorismate mutase
FE240_RS05840	COG0583	DNA-binding transcription factor activity
FE240_RS05845	COG3085	chromosome segregation
FE240_RS05850	COG1846	Transcriptional regulator
FE240_RS05850	COG1940	carbohydrate kinase activity
FE240_RS05855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FE240_RS05860	COG0363	glucosamine-6-phosphate deaminase activity
FE240_RS05865	COG2190	(PTS) system
FE240_RS05865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE240_RS05865	COG1263	PTS System
FE240_RS05875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE240_RS05880	COG0735	belongs to the Fur family
FE240_RS05890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE240_RS05905	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FE240_RS05960	COG1684	flagellar biosynthetic protein fliR
FE240_RS05970	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FE240_RS05995	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FE240_RS06000	COG0784	Response regulator, receiver
FE240_RS06000	COG2198	Histidine kinase
FE240_RS06000	COG0643	Histidine kinase
FE240_RS06010	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FE240_RS06015	COG1360	Flagellar Motor Protein
FE240_RS06020	COG1192	Involved in chromosome partitioning
FE240_RS06030	COG0835	chemotaxis
FE240_RS06040	COG4133	protoheme IX ABC transporter activity
FE240_RS06045	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE240_RS06050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE240_RS06055	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE240_RS06060	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FE240_RS06065	COG1138	Cytochrome C-type biogenesis protein
FE240_RS06070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE240_RS06075	COG4235	cytochrome complex assembly
FE240_RS06075	COG3088	subunit of a heme lyase
FE240_RS06095	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FE240_RS06115	COG0259	pyridoxamine-phosphate oxidase activity
FE240_RS06120	COG3153	acetyltransferase
FE240_RS06125	COG0701	Predicted permease
FE240_RS06130	COG2850	peptidyl-arginine hydroxylation
FE240_RS06135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FE240_RS06140	COG2915	High frequency lysogenization protein hflD homolog
FE240_RS06145	COG0482	sulfurtransferase activity
FE240_RS06170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE240_RS06175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FE240_RS06180	COG0538	isocitrate dehydrogenase activity
FE240_RS06210	COG0798	PFAM Bile acid sodium symporter
FE240_RS06225	COG1448	Aminotransferase
FE240_RS06235	COG0564	pseudouridine synthase activity
FE240_RS06250	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FE240_RS06260	COG0625	glutathione transferase activity
FE240_RS06275	COG3437	response regulator, receiver
FE240_RS06280	COG0583	DNA-binding transcription factor activity
FE240_RS06305	COG2814	Major facilitator Superfamily
FE240_RS06320	COG1960	acyl-CoA dehydrogenase activity
FE240_RS06325	COG0469	pyruvate kinase activity
FE240_RS06330	COG1737	Transcriptional regulator
FE240_RS06335	COG0837	glucose binding
FE240_RS06345	COG3088	subunit of a heme lyase
FE240_RS06345	COG4235	cytochrome complex assembly
FE240_RS06355	COG1138	Cytochrome C-type biogenesis protein
FE240_RS06360	COG3301	Polysulphide reductase, NrfD
FE240_RS06365	COG0437	4 iron, 4 sulfur cluster binding
FE240_RS06370	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FE240_RS06380	COG0247	lactate metabolic process
FE240_RS06385	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FE240_RS06390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FE240_RS06400	COG3012	SEC-C Motif Domain Protein
FE240_RS06410	COG1940	carbohydrate kinase activity
FE240_RS06410	COG1846	Transcriptional regulator
FE240_RS06415	COG1882	Formate acetyltransferase
FE240_RS06420	COG2116	formate transmembrane transporter activity
FE240_RS06425	COG1944	ATP diphosphatase activity
FE240_RS06435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FE240_RS06440	COG1368	sulfuric ester hydrolase activity
FE240_RS06445	COG0527	aspartate kinase activity
FE240_RS06450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FE240_RS06450	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FE240_RS06455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FE240_RS06475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE240_RS06480	COG0583	DNA-binding transcription factor activity
FE240_RS06485	COG1620	l-lactate permease
FE240_RS06495	COG1139	Iron-sulfur cluster binding protein
FE240_RS06535	COG0577	efflux transmembrane transporter activity
FE240_RS06550	COG2814	Major facilitator Superfamily
FE240_RS06565	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
FE240_RS06570	COG0672	)-iron permease
FE240_RS06595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FE240_RS06600	COG2885	chlorophyll binding
FE240_RS06605	COG1253	flavin adenine dinucleotide binding
FE240_RS06615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FE240_RS06620	COG0123	including yeast histone deacetylase and acetoin utilization protein
FE240_RS06625	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FE240_RS06630	COG1199	ATP-dependent helicase activity
FE240_RS06640	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FE240_RS06645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FE240_RS06655	COG4591	ABC-type transport system involved in lipoprotein release permease component
FE240_RS06660	COG1136	(ABC) transporter
FE240_RS06665	COG4591	ABC-type transport system involved in lipoprotein release permease component
FE240_RS06670	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FE240_RS06680	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FE240_RS06685	COG2894	cell division
FE240_RS06690	COG0850	regulation of cytokinetic process
FE240_RS06695	COG3100	YcgL domain-containing protein
FE240_RS06700	COG2983	Belongs to the UPF0260 family
FE240_RS06705	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FE240_RS06710	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FE240_RS06720	COG2719	SpoVR family
FE240_RS06725	COG2718	Belongs to the UPF0229 family
FE240_RS06730	COG2766	serine protein kinase
FE240_RS06740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FE240_RS06745	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FE240_RS06750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FE240_RS06755	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FE240_RS06760	COG0488	(ABC) transporter
FE240_RS06765	COG3706	GGDEF domain
FE240_RS06770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE240_RS06775	COG3162	membrane
FE240_RS06790	COG1024	Enoyl-CoA hydratase
FE240_RS06795	COG1115	amino acid carrier protein
FE240_RS06805	COG3228	Belongs to the MtfA family
FE240_RS06810	COG1584	GPR1 FUN34 yaaH family protein
FE240_RS06835	COG4770	biotin carboxylase activity
FE240_RS06845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE240_RS06850	COG1960	acyl-CoA dehydrogenase activity
FE240_RS06860	COG1960	acyl-CoA dehydrogenase activity
FE240_RS06865	COG1024	Enoyl-CoA hydratase
FE240_RS06870	COG1024	Enoyl-CoA hydratase
FE240_RS06880	COG1028	Short-chain dehydrogenase reductase Sdr
FE240_RS06890	COG0730	response to heat
FE240_RS06925	COG3121	Chaperone
FE240_RS06955	COG1342	Belongs to the UPF0251 family
FE240_RS06960	COG0583	DNA-binding transcription factor activity
FE240_RS06965	COG2723	6-phospho-beta-galactosidase activity
FE240_RS06980	COG0537	adenosine 5'-monophosphoramidase activity
FE240_RS07015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE240_RS07020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE240_RS07025	COG1733	regulation of RNA biosynthetic process
FE240_RS07040	COG2354	Protein conserved in bacteria
FE240_RS07050	COG1252	NADH dehydrogenase
FE240_RS07055	COG0393	Putative heavy-metal-binding
FE240_RS07060	COG0604	alcohol dehydrogenase
FE240_RS07075	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FE240_RS07090	COG0567	Dehydrogenase, E1 component
FE240_RS07095	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE240_RS07100	COG0045	succinate-CoA ligase (ADP-forming) activity
FE240_RS07115	COG1760	l-serine dehydratase
FE240_RS07120	COG1760	l-serine dehydratase
FE240_RS07125	COG0814	amino acid
FE240_RS07130	COG0494	nUDIX hydrolase
FE240_RS07135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FE240_RS07160	COG0581	inorganic phosphate transmembrane transporter activity
FE240_RS07165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FE240_RS07170	COG0704	Plays a role in the regulation of phosphate uptake
FE240_RS07175	COG0346	lactoylglutathione lyase activity
FE240_RS07180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FE240_RS07185	COG4660	Part of a membrane complex involved in electron transport
FE240_RS07190	COG4659	FMN binding
FE240_RS07195	COG4658	electron transport chain
FE240_RS07205	COG2878	Part of a membrane complex involved in electron transport
FE240_RS07210	COG4657	Part of a membrane complex involved in electron transport
FE240_RS07245	COG0714	Associated with various cellular activities
FE240_RS07250	COG0183	Belongs to the thiolase family
FE240_RS07255	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE240_RS07255	COG1024	Enoyl-CoA hydratase
FE240_RS07265	COG4681	YaeQ
FE240_RS07280	COG0586	Pfam SNARE associated Golgi protein
FE240_RS07285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE240_RS07295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FE240_RS07320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FE240_RS07325	COG1120	ATPase activity
FE240_RS07330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE240_RS07335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE240_RS07340	COG0673	inositol 2-dehydrogenase activity
FE240_RS07345	COG0583	DNA-binding transcription factor activity
FE240_RS07365	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FE240_RS07370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE240_RS07370	COG0574	Belongs to the PEP-utilizing enzyme family
FE240_RS07385	COG2824	Alkylphosphonate utilization operon protein PhnA
FE240_RS07390	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE240_RS07395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FE240_RS07440	COG2119	membrane
FE240_RS07445	COG0023	Translation Initiation Factor
FE240_RS07455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FE240_RS07475	COG4139	cobalamin transport
FE240_RS07480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FE240_RS07485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FE240_RS07490	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FE240_RS07495	COG0544	peptidyl-prolyl cis-trans isomerase activity
FE240_RS07500	COG0740	serine-type endopeptidase activity
FE240_RS07505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FE240_RS07510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FE240_RS07515	COG0776	regulation of translation
FE240_RS07520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE240_RS07530	COG4166	transmembrane transport
FE240_RS07535	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FE240_RS07540	COG0814	amino acid
FE240_RS07545	COG1609	Transcriptional regulator
FE240_RS07550	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_RS07550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_RS07555	COG1105	Belongs to the carbohydrate kinase PfkB family
FE240_RS07560	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FE240_RS07560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE240_RS07560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE240_RS07565	COG3313	Fe-S protein
FE240_RS07570	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FE240_RS07575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FE240_RS07605	COG1518	maintenance of DNA repeat elements
FE240_RS07610	COG1203	CRISPR-associated helicase, Cas3
FE240_RS07645	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FE240_RS07650	COG1704	LemA family
FE240_RS07655	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FE240_RS07665	COG0724	RNA recognition motif
FE240_RS07670	COG4989	oxidoreductase activity
FE240_RS07685	COG0367	asparagine synthase
FE240_RS07690	COG0647	UMP catabolic process
FE240_RS07700	COG3134	Outer membrane lipoprotein
FE240_RS07705	COG0697	spore germination
FE240_RS07710	COG1278	Cold shock
FE240_RS07715	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FE240_RS07720	COG0542	response to heat
FE240_RS07725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FE240_RS07730	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FE240_RS07735	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FE240_RS07740	COG3134	Outer membrane lipoprotein
FE240_RS07750	COG0492	ferredoxin-NADP+ reductase activity
FE240_RS07760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE240_RS07765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FE240_RS07775	COG0101	tRNA pseudouridine synthase activity
FE240_RS07780	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FE240_RS07785	COG0285	dihydrofolate synthase activity
FE240_RS07790	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FE240_RS07795	COG2920	part of a sulfur-relay system
FE240_RS07800	COG1289	transmembrane transporter activity
FE240_RS07805	COG0670	Belongs to the BI1 family
FE240_RS07845	COG0307	riboflavin synthase, alpha
FE240_RS07860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE240_RS07865	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FE240_RS07870	COG0697	spore germination
FE240_RS07875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FE240_RS07910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE240_RS07915	COG3099	Belongs to the UPF0263 family
FE240_RS07930	COG0513	Belongs to the DEAD box helicase family
FE240_RS07935	COG0386	Belongs to the glutathione peroxidase family
FE240_RS07945	COG1181	Belongs to the D-alanine--D-alanine ligase family
FE240_RS07950	COG3148	PFAM DTW domain containing protein
FE240_RS07955	COG0730	response to heat
FE240_RS07960	COG0583	DNA-binding transcription factor activity
FE240_RS07970	COG3708	Transcriptional regulator
FE240_RS07970	COG2207	Transcriptional regulator
FE240_RS07975	COG3593	DNA synthesis involved in DNA repair
FE240_RS08030	COG1011	Hydrolase
FE240_RS08035	COG1473	amidohydrolase
FE240_RS08050	COG1643	Atp-dependent helicase
FE240_RS08060	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FE240_RS08065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE240_RS08070	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FE240_RS08075	COG0709	Synthesizes selenophosphate from selenide and ATP
FE240_RS08085	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FE240_RS08095	COG1254	Belongs to the acylphosphatase family
FE240_RS08105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE240_RS08105	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE240_RS08110	COG0489	protein tyrosine kinase activity
FE240_RS08115	COG0572	uridine kinase
FE240_RS08120	COG0717	Belongs to the dCTP deaminase family
FE240_RS08125	COG0306	phosphate transporter
FE240_RS08130	COG1530	ribonuclease E activity
FE240_RS08135	COG0564	pseudouridine synthase activity
FE240_RS08145	COG0424	maF-like protein
FE240_RS08150	COG1399	metal-binding, possibly nucleic acid-binding protein
FE240_RS08155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FE240_RS08160	COG0416	fatty acid biosynthetic process
FE240_RS08165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE240_RS08190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FE240_RS08195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FE240_RS08200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FE240_RS08205	COG0470	DNA polymerase III
FE240_RS08210	COG0084	hydrolase, TatD family'
FE240_RS08225	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FE240_RS08225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FE240_RS08230	COG3008	intermembrane lipid transfer
FE240_RS08235	COG2995	paraquat-inducible protein a
FE240_RS08245	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FE240_RS08250	COG0372	Belongs to the citrate synthase family
FE240_RS08260	COG3141	response to X-ray
FE240_RS08340	COG1067	ATP-dependent peptidase activity
FE240_RS08345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FE240_RS08360	COG0488	(ABC) transporter
FE240_RS08370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FE240_RS08370	COG0116	Belongs to the methyltransferase superfamily
FE240_RS08380	COG0167	dihydroorotate dehydrogenase activity
FE240_RS08385	COG2902	Dehydrogenase
FE240_RS08395	COG0308	aminopeptidase N
FE240_RS08410	COG2501	S4 domain
FE240_RS08415	COG1132	(ABC) transporter
FE240_RS08420	COG1132	(ABC) transporter
FE240_RS08425	COG3118	belongs to the thioredoxin family
FE240_RS08430	COG0471	metal ion transport
FE240_RS08435	COG0058	SHG alpha-glucan phosphorylase activity
FE240_RS08450	COG2067	long-chain fatty acid transport protein
FE240_RS08455	COG0183	Belongs to the thiolase family
FE240_RS08470	COG3123	guanosine phosphorylase activity
FE240_RS08480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FE240_RS08485	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FE240_RS08485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE240_RS08495	COG3069	C4-dicarboxylate transmembrane transporter activity
FE240_RS08500	COG0737	Belongs to the 5'-nucleotidase family
FE240_RS08510	COG1451	nucleotide metabolic process
FE240_RS08525	COG3214	Protein conserved in bacteria
FE240_RS08530	COG2925	Exonuclease
FE240_RS08540	COG3345	alpha-galactosidase
FE240_RS08545	COG1380	Effector of murein hydrolase LrgA
FE240_RS08550	COG1346	cytolysis
FE240_RS08555	COG0295	cytidine deaminase activity
FE240_RS08575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE240_RS08585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE240_RS08595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE240_RS08605	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FE240_RS08610	COG1956	GAF domain-containing protein
FE240_RS08625	COG3278	Belongs to the heme-copper respiratory oxidase family
FE240_RS08640	COG2010	Cytochrome c
FE240_RS08665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE240_RS08670	COG0589	response to stress
FE240_RS08675	COG0037	tRNA processing
FE240_RS08700	COG1177	transmembrane transport
FE240_RS08710	COG0625	glutathione transferase activity
FE240_RS08715	COG1869	D-ribose catabolic process
FE240_RS08720	COG1129	ABC transporter
FE240_RS08725	COG1172	Belongs to the binding-protein-dependent transport system permease family
FE240_RS08730	COG1879	ABC-type sugar transport system periplasmic component
FE240_RS08735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE240_RS08740	COG1609	Transcriptional regulator
FE240_RS08745	COG2199	diguanylate cyclase activity
FE240_RS08770	COG0784	Response regulator, receiver
FE240_RS08770	COG2205	protein histidine kinase activity
FE240_RS08775	COG0776	regulation of translation
FE240_RS08780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE240_RS08780	COG0072	phenylalanine-tRNA ligase activity
FE240_RS08785	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FE240_RS08800	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FE240_RS08815	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE240_RS08870	COG0582	viral genome integration into host DNA
FE240_RS08895	COG0322	excinuclease ABC activity
FE240_RS08900	COG2197	response regulator
FE240_RS08905	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FE240_RS08910	COG2835	tetraacyldisaccharide 4'-kinase activity
FE240_RS08915	COG1663	tetraacyldisaccharide 4'-kinase activity
FE240_RS08920	COG1132	(ABC) transporter
FE240_RS08925	COG0658	competence protein
FE240_RS08925	COG2333	competence protein COMEC
FE240_RS08940	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FE240_RS08950	COG2062	phosphohistidine phosphatase, SixA
FE240_RS08960	COG0500	methyltransferase
FE240_RS09105	COG0582	viral genome integration into host DNA
FE240_RS09110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE240_RS09110	COG0519	Catalyzes the synthesis of GMP from XMP
FE240_RS09115	COG0516	GMP reductase activity
FE240_RS09115	COG0517	IMP dehydrogenase activity
FE240_RS09125	COG0366	Alpha amylase catalytic
FE240_RS09125	COG1874	Beta-galactosidase
FE240_RS09140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FE240_RS09145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FE240_RS09150	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FE240_RS09175	COG0556	nucleotide-excision repair
FE240_RS09185	COG0513	Belongs to the DEAD box helicase family
FE240_RS09190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FE240_RS09195	COG2890	protein-(glutamine-N5) methyltransferase activity
FE240_RS09200	COG2840	Smr protein MutS2
FE240_RS09220	COG0569	domain protein
FE240_RS09220	COG2985	domain, Protein
FE240_RS09230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FE240_RS09235	COG1022	Amp-dependent synthetase and ligase
FE240_RS09250	COG0861	Integral membrane protein TerC family
FE240_RS09255	COG2885	chlorophyll binding
FE240_RS09260	COG2199	diguanylate cyclase activity
FE240_RS09275	COG2154	pterin-4-alpha-carbinolamine dehydratase
FE240_RS09285	COG3768	UPF0283 membrane protein
FE240_RS09290	COG3106	COG3106 Predicted ATPase
FE240_RS09305	COG1842	Phage shock protein A
FE240_RS09310	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FE240_RS09315	COG0747	negative chemotaxis
FE240_RS09320	COG4168	peptide transport system, permease
FE240_RS09325	COG4171	peptide transport system, permease
FE240_RS09335	COG4172	Belongs to the ABC transporter superfamily
FE240_RS09345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FE240_RS09350	COG1286	toxin biosynthetic process
FE240_RS09355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FE240_RS09360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FE240_RS09365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FE240_RS09370	COG0531	amino acid
FE240_RS09370	COG1674	ftsk spoiiie
FE240_RS09380	COG0686	Belongs to the AlaDH PNT family
FE240_RS09405	COG1119	ATPase activity
FE240_RS09410	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FE240_RS09415	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FE240_RS09420	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FE240_RS09430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE240_RS09435	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FE240_RS09445	COG0205	6-phosphofructokinase activity
FE240_RS09455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FE240_RS09465	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FE240_RS09520	COG1396	sequence-specific DNA binding
FE240_RS09525	COG3135	benzoate transporter
FE240_RS09565	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FE240_RS09575	COG3477	response to acidic pH
FE240_RS09595	COG1785	Belongs to the alkaline phosphatase family
FE240_RS09615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE240_RS09620	COG2199	diguanylate cyclase activity
FE240_RS09620	COG2203	Gaf domain
FE240_RS09625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_RS09630	COG0765	amino acid transport
FE240_RS09635	COG1126	abc transporter atp-binding protein
FE240_RS09640	COG0531	amino acid
FE240_RS09655	COG2050	protein possibly involved in aromatic compounds catabolism
FE240_RS09665	COG0277	FAD linked oxidase domain protein
FE240_RS09665	COG0247	lactate metabolic process
FE240_RS09675	COG1902	pentaerythritol trinitrate reductase activity
FE240_RS09695	COG3501	Rhs element vgr protein
FE240_RS09705	COG0583	DNA-binding transcription factor activity
FE240_RS09710	COG0733	neurotransmitter:sodium symporter activity
FE240_RS09720	COG0656	L-ascorbic acid biosynthetic process
FE240_RS09725	COG2814	Major facilitator Superfamily
FE240_RS09730	COG2249	NAD(P)H dehydrogenase (quinone) activity
FE240_RS09740	COG1294	oxidase, subunit
FE240_RS09745	COG1271	oxidase subunit
FE240_RS09750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE240_RS09755	COG2979	Protein of unknown function (DUF533)
FE240_RS09760	COG2979	Protein of unknown function (DUF533)
FE240_RS09780	COG1228	amidohydrolase
FE240_RS09785	COG1166	arginine decarboxylase activity
FE240_RS09795	COG2195	Cleaves the N-terminal amino acid of tripeptides
FE240_RS09800	COG0204	Acyl-transferase
FE240_RS09820	COG0583	DNA-binding transcription factor activity
FE240_RS09830	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FE240_RS09835	COG0302	gtp cyclohydrolase
FE240_RS09840	COG0303	'Molybdopterin
FE240_RS09845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FE240_RS09855	COG2267	carboxylic ester hydrolase activity
FE240_RS09860	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FE240_RS09875	COG0314	molybdopterin synthase activity
FE240_RS09880	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FE240_RS09885	COG0315	cyclic pyranopterin monophosphate synthase activity
FE240_RS09890	COG0521	Mo-molybdopterin cofactor biosynthetic process
FE240_RS09895	COG3005	denitrification pathway
FE240_RS09905	COG0348	domain, Protein
FE240_RS09910	COG0437	4 iron, 4 sulfur cluster binding
FE240_RS09915	COG0243	molybdopterin cofactor binding
FE240_RS09920	COG3062	negative regulation of establishment of protein localization
FE240_RS09925	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE240_RS09925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE240_RS09930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FE240_RS09935	COG3850	Histidine kinase
FE240_RS09940	COG2197	response regulator
FE240_RS09990	COG3132	Protein of unknown function, DUF480
FE240_RS10005	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FE240_RS10020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FE240_RS10030	COG0562	UDP-galactopyranose mutase
FE240_RS10045	COG2244	polysaccharide biosynthetic process
FE240_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
FE240_RS10060	COG1083	cytidylyl-transferase
FE240_RS10065	COG0673	inositol 2-dehydrogenase activity
FE240_RS10070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FE240_RS10080	COG2089	acid synthase
FE240_RS10085	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FE240_RS10090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FE240_RS10105	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FE240_RS10105	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FE240_RS10110	COG0509	glycine decarboxylation via glycine cleavage system
FE240_RS10115	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FE240_RS10120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE240_RS10125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE240_RS10135	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FE240_RS10145	COG2814	Major facilitator Superfamily
FE240_RS10150	COG0625	glutathione transferase activity
FE240_RS10155	COG0483	inositol monophosphate 1-phosphatase activity
FE240_RS10160	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FE240_RS10180	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FE240_RS10185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FE240_RS10190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FE240_RS10195	COG0121	glutamine amidotransferase
FE240_RS10200	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FE240_RS10210	COG0784	Response regulator, receiver
FE240_RS10210	COG3437	response regulator, receiver
FE240_RS10220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FE240_RS10225	COG0328	RNA-DNA hybrid ribonuclease activity
FE240_RS10230	COG2226	methyltransferase
FE240_RS10235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE240_RS10240	COG1388	LysM domain
FE240_RS10240	COG0741	lytic transglycosylase activity
FE240_RS10245	COG1686	Belongs to the peptidase S11 family
FE240_RS10255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE240_RS10260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE240_RS10265	COG4134	Bacterial extracellular solute-binding protein
FE240_RS10270	COG4135	transport system, permease component
FE240_RS10275	COG4136	ATPase activity
FE240_RS10280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FE240_RS10290	COG3634	alkyl hydroperoxide reductase activity
FE240_RS10295	COG3021	interspecies interaction between organisms
FE240_RS10305	COG1607	acyl-coa hydrolase
FE240_RS10310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE240_RS10330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FE240_RS10340	COG2911	Protein conserved in bacteria
FE240_RS10345	COG0729	surface antigen
FE240_RS10355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE240_RS10360	COG0417	DNA replication proofreading
FE240_RS10370	COG0840	transmembrane signaling receptor activity
FE240_RS10375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE240_RS10385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FE240_RS10390	COG0563	adenylate kinase activity
FE240_RS10395	COG0326	Molecular chaperone. Has ATPase activity
FE240_RS10400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FE240_RS10425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FE240_RS10430	COG2832	Protein of unknown function (DUF454)
FE240_RS10435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE240_RS10445	COG0697	spore germination
FE240_RS10460	COG0318	PFAM AMP-dependent synthetase and ligase
FE240_RS10470	COG3065	identical protein binding
FE240_RS10475	COG1214	PFAM Peptidase M22, glycoprotease
FE240_RS10480	COG1199	ATP-dependent helicase activity
FE240_RS10490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FE240_RS10495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FE240_RS10500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FE240_RS10505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FE240_RS10505	COG0131	Imidazoleglycerol-phosphate dehydratase
FE240_RS10510	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FE240_RS10515	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FE240_RS10520	COG0107	imidazoleglycerol-phosphate synthase activity
FE240_RS10525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FE240_RS10525	COG0140	phosphoribosyl-ATP diphosphatase activity
FE240_RS10540	COG2951	lytic endotransglycosylase activity
FE240_RS10545	COG1435	thymidine kinase activity
FE240_RS10550	COG1757	Na H antiporter
FE240_RS10555	COG2916	Histone family protein nucleoid-structuring protein H-NS
FE240_RS10560	COG2096	Adenosyltransferase
FE240_RS10565	COG3530	Putative quorum-sensing-regulated virulence factor
FE240_RS10570	COG0602	queuosine metabolic process
FE240_RS10575	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FE240_RS10595	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FE240_RS10605	COG0776	regulation of translation
FE240_RS10610	COG0539	negative regulation of cytoplasmic translation
FE240_RS10615	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FE240_RS10620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FE240_RS10625	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FE240_RS10640	COG5377	YqaJ viral recombinase family
FE240_RS10740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FE240_RS10805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_RS10815	COG1242	4 iron, 4 sulfur cluster binding
FE240_RS10820	COG0067	glutamate synthase
FE240_RS10820	COG0070	glutamate synthase
FE240_RS10820	COG0069	glutamate synthase activity
FE240_RS10825	COG0493	'glutamate synthase
FE240_RS10845	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FE240_RS10855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FE240_RS10875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE240_RS10880	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FE240_RS10885	COG2188	Transcriptional regulator
FE240_RS10890	COG1840	ABC-type Fe3 transport system, periplasmic component
FE240_RS10895	COG3842	ATPase activity
FE240_RS10905	COG0301	tRNA thio-modification
FE240_RS10905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FE240_RS10925	COG3300	MHYT domain
FE240_RS10925	COG5001	Diguanylate cyclase
FE240_RS10930	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FE240_RS10965	COG2431	L-lysine efflux transmembrane transporter activity
FE240_RS10970	COG1301	dicarboxylic acid transport
FE240_RS10985	COG3724	N-succinylarginine dihydrolase activity
FE240_RS10990	COG0616	signal peptide processing
FE240_RS10995	COG1028	Short-chain dehydrogenase reductase Sdr
FE240_RS11000	COG0583	DNA-binding transcription factor activity
FE240_RS11010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FE240_RS11025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FE240_RS11030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FE240_RS11045	COG0659	secondary active sulfate transmembrane transporter activity
FE240_RS11110	COG0582	viral genome integration into host DNA
FE240_RS11120	COG2314	TM2 domain
FE240_RS11135	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE240_RS11135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE240_RS11170	COG1278	Cold shock
FE240_RS11190	COG0586	Pfam SNARE associated Golgi protein
FE240_RS11220	COG0840	transmembrane signaling receptor activity
FE240_RS11230	COG3706	GGDEF domain
FE240_RS11240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FE240_RS11250	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FE240_RS11260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FE240_RS11265	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FE240_RS11270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE240_RS11300	COG0601	transmembrane transport
FE240_RS11305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE240_RS11310	COG0444	Belongs to the ABC transporter superfamily
FE240_RS11315	COG4608	Belongs to the ABC transporter superfamily
FE240_RS11325	COG2971	BadF BadG BcrA BcrD
FE240_RS11340	COG0840	transmembrane signaling receptor activity
FE240_RS11345	COG0840	transmembrane signaling receptor activity
FE240_RS11355	COG2020	methyltransferase activity
FE240_RS11360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FE240_RS11365	COG0861	Integral membrane protein TerC family
FE240_RS11380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE240_RS11385	COG0601	transmembrane transport
FE240_RS11395	COG2095	MarC family integral membrane protein
FE240_RS11400	COG1454	alcohol dehydrogenase
FE240_RS11400	COG1012	belongs to the aldehyde dehydrogenase family
FE240_RS11410	COG0217	transcriptional regulatory protein
FE240_RS11415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FE240_RS11425	COG1801	Protein of unknown function DUF72
FE240_RS11430	COG4106	trans-aconitate 2-methyltransferase activity
FE240_RS11435	COG0500	methyltransferase
FE240_RS11455	COG0583	DNA-binding transcription factor activity
FE240_RS11460	COG2233	PERMEase
FE240_RS11465	COG0281	malic enzyme
FE240_RS11495	COG1032	radical SAM domain protein
FE240_RS11520	COG2199	diguanylate cyclase activity
FE240_RS11525	COG1752	Esterase of the alpha-beta hydrolase superfamily
FE240_RS11545	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FE240_RS11545	COG2885	chlorophyll binding
FE240_RS11555	COG2914	Belongs to the UPF0125 (RnfH) family
FE240_RS11560	COG2867	negative regulation of translational initiation
FE240_RS11565	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FE240_RS11625	COG0814	amino acid
FE240_RS11630	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FE240_RS11635	COG1982	Orn Lys Arg decarboxylase major
FE240_RS11640	COG0531	amino acid
FE240_RS11645	COG3710	Transcriptional regulator
FE240_RS11650	COG0825	malonyl-CoA metabolic process
FE240_RS11660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FE240_RS11665	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE240_RS11670	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE240_RS11675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FE240_RS11680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE240_RS11695	COG0750	zinc metalloprotease
FE240_RS11700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FE240_RS11705	COG0575	Belongs to the CDS family
FE240_RS11710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FE240_RS11715	COG0233	cytoplasmic translational termination
FE240_RS11720	COG0528	UMP kinase activity
FE240_RS11725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FE240_RS11730	COG0052	Belongs to the universal ribosomal protein uS2 family
FE240_RS11735	COG0024	Methionine aminopeptidase
FE240_RS11740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FE240_RS11745	COG2171	N-acyltransferase activity
FE240_RS11755	COG1263	PTS System
FE240_RS11755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE240_RS11765	COG4580	involved in the transport of maltose and maltodextrins
FE240_RS11770	COG0281	malic enzyme
FE240_RS11775	COG2207	Transcriptional regulator
FE240_RS11780	COG0534	Mate efflux family protein
FE240_RS11800	COG1115	amino acid carrier protein
FE240_RS11805	COG0019	diaminopimelate decarboxylase activity
FE240_RS11815	COG0678	peroxiredoxin activity
FE240_RS11825	COG1126	abc transporter atp-binding protein
FE240_RS11830	COG0765	amino acid transport
FE240_RS11835	COG4597	amino acid ABC transporter
FE240_RS11840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_RS11855	COG0545	Peptidyl-prolyl cis-trans isomerase
FE240_RS11865	COG1940	carbohydrate kinase activity
FE240_RS11885	COG5002	protein histidine kinase activity
FE240_RS11890	COG0745	RESPONSE REGULATOR receiver
FE240_RS11900	COG0300	oxidoreductase activity
FE240_RS11915	COG2840	Smr protein MutS2
FE240_RS11920	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FE240_RS11945	COG0419	ATPase involved in DNA repair
FE240_RS11950	COG0420	3'-5' exonuclease activity
FE240_RS11960	COG2974	May be involved in recombination
FE240_RS11970	COG0583	DNA-binding transcription factor activity
FE240_RS11985	COG1263	PTS System
FE240_RS11985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FE240_RS11990	COG1874	Beta-galactosidase
FE240_RS11995	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FE240_RS12000	COG3833	ABC-type maltose transport systems, permease component
FE240_RS12005	COG1175	transmembrane transport
FE240_RS12010	COG2182	Extracellular solute-binding protein
FE240_RS12035	COG4580	involved in the transport of maltose and maltodextrins
FE240_RS12040	COG1609	Transcriptional regulator
FE240_RS12045	COG0826	peptidase U32
FE240_RS12050	COG1280	lysine exporter protein (LysE YggA)
FE240_RS12060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE240_RS12100	COG0534	Mate efflux family protein
FE240_RS12125	COG0300	oxidoreductase activity
FE240_RS12140	COG0642	Histidine kinase
FE240_RS12150	COG0674	pyruvate-flavodoxin oxidoreductase activity
FE240_RS12150	COG1013	pyruvate-flavodoxin oxidoreductase activity
FE240_RS12150	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FE240_RS12150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FE240_RS12155	COG0493	'glutamate synthase
FE240_RS12160	COG3217	Mosc domain protein beta barrel domain protein
FE240_RS12160	COG0633	Ferredoxin
FE240_RS12160	COG3217	Mosc domain protein beta barrel domain protein
FE240_RS12160	COG0633	Ferredoxin
FE240_RS12165	COG0501	Belongs to the peptidase M48B family
FE240_RS12170	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FE240_RS12175	COG2226	methyltransferase
FE240_RS12180	COG0156	8-amino-7-oxononanoate synthase activity
FE240_RS12185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FE240_RS12200	COG0017	Asparaginyl-tRNA synthetase
FE240_RS12205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FE240_RS12215	COG2199	diguanylate cyclase activity
FE240_RS12225	COG3590	peptidase
FE240_RS12245	COG3098	single-species biofilm formation
FE240_RS12270	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FE240_RS12285	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FE240_RS12285	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FE240_RS12300	COG1611	Belongs to the LOG family
FE240_RS12305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE240_RS12310	COG0473	3-isopropylmalate dehydrogenase activity
FE240_RS12320	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FE240_RS12335	COG0583	DNA-binding transcription factor activity
FE240_RS12340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FE240_RS12355	COG2991	Protein conserved in bacteria
FE240_RS12360	COG1477	protein flavinylation
FE240_RS12370	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FE240_RS12375	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FE240_RS12380	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FE240_RS12385	COG1805	sodium ion transport
FE240_RS12395	COG0271	Belongs to the BolA IbaG family
FE240_RS12405	COG2813	Specifically methylates the guanine in position
FE240_RS12420	COG2211	Major facilitator Superfamily
FE240_RS12425	COG3248	Nucleoside-binding outer membrane protein
FE240_RS12430	COG1666	GTP binding
FE240_RS12435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FE240_RS12460	COG0633	Ferredoxin
FE240_RS12465	COG0443	Heat shock 70 kDa protein
FE240_RS12470	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FE240_RS12480	COG0822	iron-sulfur transferase activity
FE240_RS12485	COG1104	cysteine desulfurase activity
FE240_RS12490	COG1959	2 iron, 2 sulfur cluster binding
FE240_RS12505	COG3154	lipid carrier protein
FE240_RS12510	COG0826	peptidase U32
FE240_RS12515	COG0826	peptidase U32
FE240_RS12525	COG2897	thiosulfate sulfurtransferase activity
FE240_RS12530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE240_RS12535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE240_RS12540	COG1862	Preprotein translocase
FE240_RS12545	COG0343	queuine tRNA-ribosyltransferase activity
FE240_RS12550	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FE240_RS12555	COG0517	IMP dehydrogenase activity
FE240_RS12570	COG1393	Belongs to the ArsC family
FE240_RS12580	COG4783	chaperone-mediated protein folding
FE240_RS12585	COG0425	Belongs to the sulfur carrier protein TusA family
FE240_RS12605	COG3842	ATPase activity
FE240_RS12610	COG3833	ABC-type maltose transport systems, permease component
FE240_RS12615	COG1175	transmembrane transport
FE240_RS12625	COG3081	Nucleoid-associated protein
FE240_RS12630	COG3082	Protein of unknown function (DUF1414)
FE240_RS12645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FE240_RS12650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE240_RS12655	COG1151	hydroxylamine reductase activity
FE240_RS12660	COG0783	Belongs to the Dps family
FE240_RS12675	COG3272	Protein of unknown function (DUF1722)
FE240_RS12700	COG0077	Prephenate dehydratase
FE240_RS12700	COG1605	Chorismate mutase
FE240_RS12735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FE240_RS12800	COG2814	Major facilitator Superfamily
FE240_RS12805	COG0109	protoheme IX farnesyltransferase activity
FE240_RS12810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FE240_RS12815	COG1845	cytochrome c oxidase, subunit III
FE240_RS12820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FE240_RS12825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FE240_RS12830	COG3152	Membrane
FE240_RS12850	COG1442	glycosyl transferase family 8
FE240_RS12875	COG0438	transferase activity, transferring glycosyl groups
FE240_RS12895	COG0489	protein tyrosine kinase activity
FE240_RS12895	COG3206	protein involved in exopolysaccharide biosynthesis
FE240_RS12935	COG2375	cellular response to nickel ion
FE240_RS12945	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FE240_RS12950	COG2200	EAL domain
FE240_RS12955	COG0071	Belongs to the small heat shock protein (HSP20) family
FE240_RS12960	COG0545	Peptidyl-prolyl cis-trans isomerase
FE240_RS12965	COG4771	TonB-dependent receptor
FE240_RS12970	COG0741	lytic transglycosylase activity
FE240_RS12980	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FE240_RS12990	COG0697	spore germination
FE240_RS12995	COG4565	transcriptional regulatory protein
FE240_RS13000	COG3290	protein histidine kinase activity
FE240_RS13025	COG4608	Belongs to the ABC transporter superfamily
FE240_RS13030	COG0444	Belongs to the ABC transporter superfamily
FE240_RS13040	COG4239	(ABC) transporter, permease
FE240_RS13045	COG4174	ABC transporter (Permease)
FE240_RS13050	COG4206	TonB-dependent receptor
FE240_RS13060	COG0811	peptide transport
FE240_RS13065	COG0811	peptide transport
FE240_RS13070	COG0848	biopolymer transport protein
FE240_RS13085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FE240_RS13090	COG2011	ABC-type metal ion transport system permease component
FE240_RS13095	COG1464	Belongs to the NlpA lipoprotein family
FE240_RS13115	COG0784	Response regulator, receiver
FE240_RS13115	COG2198	Histidine kinase
FE240_RS13115	COG5002	protein histidine kinase activity
FE240_RS13125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE240_RS13130	COG0191	fructose-bisphosphate aldolase activity
FE240_RS13135	COG0126	phosphoglycerate kinase activity
FE240_RS13140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FE240_RS13145	COG1940	carbohydrate kinase activity
FE240_RS13150	COG0545	Peptidyl-prolyl cis-trans isomerase
FE240_RS13160	COG2900	Belongs to the SlyX family
FE240_RS13165	COG1047	Peptidyl-prolyl cis-trans
FE240_RS13170	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FE240_RS13180	COG0835	chemotaxis
FE240_RS13180	COG0784	Response regulator, receiver
FE240_RS13185	COG0429	hydrolase of the alpha beta-hydrolase fold
FE240_RS13190	COG5001	Diguanylate cyclase
FE240_RS13190	COG4251	negative regulation of phosphorylation
FE240_RS13190	COG2203	Gaf domain
FE240_RS13190	COG3706	GGDEF domain
FE240_RS13200	COG3089	Belongs to the UPF0270 family
FE240_RS13205	COG3954	Phosphoribulokinase
FE240_RS13220	COG1765	OsmC-like protein
FE240_RS13230	COG2226	methyltransferase
FE240_RS13235	COG4221	oxidoreductase activity
FE240_RS13250	COG1024	Enoyl-CoA hydratase
FE240_RS13260	COG4166	transmembrane transport
FE240_RS13270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE240_RS13285	COG1278	Cold shock
FE240_RS13310	COG0737	Belongs to the 5'-nucleotidase family
FE240_RS13330	COG2204	response regulator
FE240_RS13350	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FE240_RS13360	COG3091	SprT-like family
FE240_RS13370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FE240_RS13375	COG0189	ligase activity
FE240_RS13380	COG1678	Uncharacterized ACR, COG1678
FE240_RS13385	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FE240_RS13420	COG3188	usher protein
FE240_RS13425	COG3121	Chaperone
FE240_RS13435	COG1115	amino acid carrier protein
FE240_RS13440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FE240_RS13455	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FE240_RS13460	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FE240_RS13465	COG0148	phosphopyruvate hydratase activity
FE240_RS13470	COG0504	CTP synthase activity
FE240_RS13475	COG3956	TIGRFAM MazG family protein
FE240_RS13480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE240_RS13485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FE240_RS13495	COG4807	Protein conserved in bacteria
FE240_RS13500	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE240_RS13505	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FE240_RS13510	COG1381	Involved in DNA repair and RecF pathway recombination
FE240_RS13520	COG0571	ribonuclease III activity
FE240_RS13530	COG0481	GTPase activity
FE240_RS13540	COG3026	antisigma factor binding
FE240_RS13550	COG1595	DNA-templated transcription, initiation
FE240_RS13555	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FE240_RS13565	COG0114	fumarate hydratase activity
FE240_RS13575	COG0432	Pfam Uncharacterised protein family UPF0047
FE240_RS13580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FE240_RS13595	COG3150	esterase
FE240_RS13610	COG0494	nUDIX hydrolase
FE240_RS13615	COG1538	Outer membrane efflux protein
FE240_RS13630	COG1842	Phage shock protein A
FE240_RS13635	COG0204	Acyl-transferase
FE240_RS13650	COG0583	DNA-binding transcription factor activity
FE240_RS13655	COG4221	oxidoreductase activity
FE240_RS13680	COG2329	Antibiotic biosynthesis monooxygenase
FE240_RS13690	COG1051	belongs to the nudix hydrolase family
FE240_RS13705	COG0354	folic acid binding
FE240_RS13725	COG1324	tolerance protein
FE240_RS13730	COG4232	protein-disulfide reductase activity
FE240_RS13740	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FE240_RS13745	COG2816	NAD+ diphosphatase activity
FE240_RS13765	COG3022	response to hydroperoxide
FE240_RS13780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FE240_RS13785	COG0762	integral membrane protein
FE240_RS13790	COG1872	DUF167
FE240_RS13805	COG0776	regulation of translation
FE240_RS13815	COG1388	LysM domain
FE240_RS13815	COG4942	peptidase
FE240_RS13820	COG1238	metal cluster binding
FE240_RS13825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FE240_RS13830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FE240_RS13835	COG0585	pseudouridine synthase activity
FE240_RS13845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FE240_RS13850	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FE240_RS13855	COG1301	dicarboxylic acid transport
FE240_RS13860	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FE240_RS13865	COG2912	Transglutaminase-like superfamily
FE240_RS13875	COG2890	protein-(glutamine-N5) methyltransferase activity
FE240_RS13880	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FE240_RS13885	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FE240_RS13890	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FE240_RS13895	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FE240_RS13900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FE240_RS13905	COG0193	aminoacyl-tRNA hydrolase activity
FE240_RS13910	COG0012	GTP binding
FE240_RS13920	COG5377	YqaJ viral recombinase family
FE240_RS13970	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FE240_RS13975	COG0732	type I restriction modification DNA specificity domain
FE240_RS14005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FE240_RS14010	COG1204	response to ionizing radiation
FE240_RS14080	COG0471	metal ion transport
FE240_RS14080	COG0490	domain, Protein
FE240_RS14085	COG1049	propionate catabolic process, 2-methylcitrate cycle
FE240_RS14090	COG1752	Esterase of the alpha-beta hydrolase superfamily
FE240_RS14100	COG3706	GGDEF domain
FE240_RS14105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE240_RS14110	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE240_RS14115	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FE240_RS14120	COG2186	Transcriptional regulator
FE240_RS14145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FE240_RS14165	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FE240_RS14170	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FE240_RS14175	COG0494	nUDIX hydrolase
FE240_RS14180	COG0653	protein targeting
FE240_RS14190	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FE240_RS14195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FE240_RS14200	COG0849	cell division
FE240_RS14210	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE240_RS14215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FE240_RS14220	COG0772	Belongs to the SEDS family
FE240_RS14225	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FE240_RS14230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE240_RS14235	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FE240_RS14240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FE240_RS14250	COG3116	cell division
FE240_RS14255	COG0275	rRNA processing
FE240_RS14260	COG2001	Belongs to the MraZ family
FE240_RS14270	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FE240_RS14275	COG3107	peptidoglycan biosynthetic process
FE240_RS14280	COG0792	nuclease activity
FE240_RS14285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FE240_RS14290	COG2823	Periplasmic or secreted lipoprotein
FE240_RS14295	COG2969	positive regulation of protein catabolic process
FE240_RS14300	COG0625	glutathione transferase activity
FE240_RS14305	COG2857	Cytochrome c1
FE240_RS14310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FE240_RS14315	COG0723	plastoquinol--plastocyanin reductase activity
FE240_RS14320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FE240_RS14325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FE240_RS14330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FE240_RS14340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE240_RS14345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE240_RS14350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_RS14355	COG1660	Displays ATPase and GTPase activities
FE240_RS14360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_RS14365	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FE240_RS14370	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FE240_RS14375	COG1137	ATPase activity
FE240_RS14380	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FE240_RS14390	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FE240_RS14395	COG0517	IMP dehydrogenase activity
FE240_RS14395	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FE240_RS14400	COG1127	ABC transporter
FE240_RS14405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FE240_RS14410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FE240_RS14415	COG2854	intermembrane phospholipid transfer
FE240_RS14425	COG5007	Belongs to the BolA IbaG family
FE240_RS14430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FE240_RS14435	COG0312	modulator of DNA gyrase
FE240_RS14440	COG3028	Belongs to the UPF0307 family
FE240_RS14450	COG0477	Major facilitator Superfamily
FE240_RS14460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE240_RS14465	COG0359	binds to the 23S rRNA
FE240_RS14470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FE240_RS14475	COG0360	Binds together with S18 to 16S ribosomal RNA
FE240_RS14480	COG1914	H( )-stimulated, divalent metal cation uptake system
FE240_RS14525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FE240_RS14530	COG0583	DNA-binding transcription factor activity
FE240_RS14535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FE240_RS14550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FE240_RS14560	COG1970	mechanosensitive ion channel activity
FE240_RS14565	COG4974	Belongs to the 'phage' integrase family
FE240_RS14570	COG0716	FMN binding
FE240_RS14590	COG1376	ErfK ybiS ycfS ynhG family protein
FE240_RS14630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FE240_RS14635	COG0527	aspartate kinase activity
FE240_RS14640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FE240_RS14645	COG2137	regulation of response to DNA damage stimulus
FE240_RS14650	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FE240_RS14655	COG1546	Belongs to the CinA family
FE240_RS14715	COG3039	Transposase
FE240_RS14735	COG2916	Histone family protein nucleoid-structuring protein H-NS
FE240_RS14755	COG0582	viral genome integration into host DNA
FE240_RS14760	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FE240_RS14780	COG3068	Protein conserved in bacteria
FE240_RS14795	COG0312	modulator of DNA gyrase
FE240_RS14800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE240_RS14810	COG3164	Protein of unknown function
FE240_RS14815	COG1530	ribonuclease E activity
FE240_RS14820	COG0424	maF-like protein
FE240_RS14825	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FE240_RS14830	COG1792	Involved in formation and maintenance of cell shape
FE240_RS14835	COG1077	Cell shape determining protein MreB Mrl
FE240_RS14865	COG2165	general secretion pathway protein
FE240_RS14870	COG2165	general secretion pathway protein
FE240_RS14880	COG1459	type II secretion system
FE240_RS14885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FE240_RS14895	COG3409	Peptidoglycan-binding domain 1 protein
FE240_RS14895	COG3267	Type II secretory pathway component ExeA
FE240_RS14935	COG0741	lytic transglycosylase activity
FE240_RS14935	COG1388	LysM domain
FE240_RS14950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FE240_RS14955	COG1191	sigma factor activity
FE240_RS14980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE240_RS14995	COG1706	bacterial-type flagellum-dependent cell motility
FE240_RS15000	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FE240_RS15005	COG4786	Flagellar basal body rod
FE240_RS15015	COG1749	Flagellar hook protein flgE
FE240_RS15025	COG1558	bacterial-type flagellum-dependent cell motility
FE240_RS15030	COG1815	bacterial-type flagellum-dependent cell motility
FE240_RS15085	COG1677	Flagellar hook-basal body complex protein FliE
FE240_RS15110	COG1987	bacterial-type flagellum assembly
FE240_RS15130	COG3842	ATPase activity
FE240_RS15140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE240_RS15155	COG1773	rubredoxin
FE240_RS15160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FE240_RS15165	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FE240_RS15170	COG5557	Pfam Polysulphide reductase, NrfD
FE240_RS15175	COG0437	4 iron, 4 sulfur cluster binding
FE240_RS15180	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FE240_RS15185	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FE240_RS15190	COG0375	protein maturation
FE240_RS15205	COG0298	carbon dioxide binding
FE240_RS15210	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FE240_RS15220	COG1349	DNA-binding transcription factor activity
FE240_RS15230	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FE240_RS15240	COG0840	transmembrane signaling receptor activity
FE240_RS15245	COG4991	sh3 domain protein
FE240_RS15255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FE240_RS15260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FE240_RS15265	COG1610	YqeY-like protein
FE240_RS15270	COG0358	DNA primase activity
FE240_RS15275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FE240_RS15295	COG0542	response to heat
FE240_RS15300	COG2502	aspartate--ammonia ligase
FE240_RS15305	COG1522	sequence-specific DNA binding
FE240_RS15315	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FE240_RS15320	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FE240_RS15325	COG1979	alcohol dehydrogenase
FE240_RS15330	COG2207	Transcriptional regulator
FE240_RS15345	COG0540	Belongs to the ATCase OTCase family
FE240_RS15350	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FE240_RS15355	COG1438	arginine binding
FE240_RS15375	COG0671	phosphoesterase, PA-phosphatase related
FE240_RS15380	COG0628	permease
FE240_RS15385	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FE240_RS15385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE240_RS15385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE240_RS15390	COG1461	Dihydroxyacetone kinase
FE240_RS15395	COG2376	Dihydroxyacetone kinase
FE240_RS15400	COG2252	PERMEase
FE240_RS15420	COG3112	Uncharacterised protein family (UPF0231)
FE240_RS15425	COG1929	Belongs to the glycerate kinase type-1 family
FE240_RS15445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FE240_RS15460	COG2926	Belongs to the UPF0265 family
FE240_RS15500	COG1902	pentaerythritol trinitrate reductase activity
FE240_RS15515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FE240_RS15535	COG1357	PFAM Pentapeptide repeats (8 copies)
FE240_RS15585	COG0488	(ABC) transporter
FE240_RS15675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FE240_RS15725	COG5642	Protein of unknown function (DUF2384)
FE240_RS15730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE240_RS15755	COG4974	Belongs to the 'phage' integrase family
FE240_RS15795	COG1575	Belongs to the MenA family. Type 1 subfamily
FE240_RS15800	COG1169	isochorismate synthase
FE240_RS15805	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FE240_RS15815	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FE240_RS15820	COG1441	menaquinone biosynthetic process
FE240_RS15830	COG2949	membrane
FE240_RS15845	COG3047	cAMP biosynthetic process
FE240_RS15850	COG3706	GGDEF domain
FE240_RS15855	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FE240_RS15865	COG2771	luxR family
FE240_RS15870	COG3916	Acyl-homoserine-lactone synthase
FE240_RS15875	COG1733	regulation of RNA biosynthetic process
FE240_RS15915	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FE240_RS15920	COG1047	Peptidyl-prolyl cis-trans
FE240_RS15925	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FE240_RS15930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FE240_RS15935	COG0196	riboflavin kinase activity
FE240_RS15940	COG0728	peptidoglycan biosynthetic process
FE240_RS15945	COG0268	Binds directly to 16S ribosomal RNA
FE240_RS15950	COG0640	Transcriptional regulator
FE240_RS15955	COG0583	DNA-binding transcription factor activity
FE240_RS15960	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FE240_RS15965	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FE240_RS15970	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FE240_RS15980	COG1051	belongs to the nudix hydrolase family
FE240_RS15985	COG3066	DNA modification
FE240_RS15995	COG0335	large ribosomal subunit rRNA binding
FE240_RS16000	COG0336	Belongs to the RNA methyltransferase TrmD family
FE240_RS16005	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FE240_RS16010	COG0228	four-way junction DNA binding
FE240_RS16015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FE240_RS16020	COG4137	Cytochrome C assembly protein
FE240_RS16025	COG4536	flavin adenine dinucleotide binding
FE240_RS16035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE240_RS16035	COG1017	nitric oxide dioxygenase activity
FE240_RS16040	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FE240_RS16045	COG0039	L-malate dehydrogenase activity
FE240_RS16050	COG4160	amino acid transport
FE240_RS16055	COG4215	(ABC) transporter
FE240_RS16060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE240_RS16065	COG1126	abc transporter atp-binding protein
FE240_RS16070	COG1438	arginine binding
FE240_RS16075	COG2837	iron assimilation
FE240_RS16080	COG3842	ATPase activity
FE240_RS16090	COG1840	ABC-type Fe3 transport system, periplasmic component
FE240_RS16095	COG0347	Belongs to the P(II) protein family
FE240_RS16140	COG3118	belongs to the thioredoxin family
FE240_RS16140	COG0457	Tetratricopeptide repeat
FE240_RS16145	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FE240_RS16155	COG1215	transferase activity, transferring glycosyl groups
FE240_RS16170	COG2194	sulfuric ester hydrolase activity
FE240_RS16175	COG1448	Aminotransferase
FE240_RS16185	COG0840	transmembrane signaling receptor activity
FE240_RS16225	COG1522	sequence-specific DNA binding
FE240_RS16240	COG3005	denitrification pathway
FE240_RS16245	COG0243	molybdopterin cofactor binding
FE240_RS16250	COG4771	TonB-dependent receptor
FE240_RS16265	COG0006	proline dipeptidase activity
FE240_RS16275	COG3133	Outer membrane lipoprotein
FE240_RS16285	COG0561	phosphatase activity
FE240_RS16290	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FE240_RS16310	COG0513	Belongs to the DEAD box helicase family
FE240_RS16320	COG1403	HNH endonuclease
FE240_RS16325	COG0189	ligase activity
FE240_RS16340	COG1218	3'(2'),5'-bisphosphate nucleotidase
FE240_RS16345	COG0494	nUDIX hydrolase
FE240_RS16355	COG1011	Hydrolase
FE240_RS16360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FE240_RS16375	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FE240_RS16380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FE240_RS16390	COG3078	GTPase activator activity
FE240_RS16400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FE240_RS16405	COG0408	coproporphyrinogen oxidase activity
FE240_RS16410	COG0009	L-threonylcarbamoyladenylate synthase
FE240_RS16415	COG0551	DNA topoisomerase type I activity
FE240_RS16420	COG2922	Belongs to the Smg family
FE240_RS16425	COG0758	DNA mediated transformation
FE240_RS16435	COG0242	peptide deformylase activity
FE240_RS16440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FE240_RS16445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FE240_RS16445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FE240_RS16450	COG0569	domain protein
FE240_RS16455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FE240_RS16460	COG1322	Protein conserved in bacteria
FE240_RS16480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE240_RS16485	COG0583	DNA-binding transcription factor activity
FE240_RS16490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE240_RS16490	COG0519	Catalyzes the synthesis of GMP from XMP
FE240_RS16495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FE240_RS16500	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FE240_RS16500	COG0662	Cupin 2, conserved barrel domain protein
FE240_RS16505	COG1012	belongs to the aldehyde dehydrogenase family
FE240_RS16555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FE240_RS16560	COG0210	DNA helicase
FE240_RS16565	COG0842	Transport permease protein
FE240_RS16570	COG0842	Transport permease protein
FE240_RS16575	COG1131	(ABC) transporter
FE240_RS16580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_RS16590	COG0583	DNA-binding transcription factor activity
FE240_RS16610	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FE240_RS16625	COG0018	arginyl-trna synthetase
FE240_RS16635	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FE240_RS16640	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FE240_RS16645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE240_RS16655	COG2116	formate transmembrane transporter activity
FE240_RS16660	COG1648	precorrin-2 dehydrogenase activity
FE240_RS16660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE240_RS16665	COG2239	Acts as a magnesium transporter
FE240_RS16680	COG0438	transferase activity, transferring glycosyl groups
FE240_RS16685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE240_RS16690	COG0438	transferase activity, transferring glycosyl groups
FE240_RS16700	COG1309	transcriptional regulator
FE240_RS16710	COG1063	alcohol dehydrogenase
FE240_RS16715	COG0840	transmembrane signaling receptor activity
FE240_RS16725	COG1129	ABC transporter
FE240_RS16735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FE240_RS16740	COG1085	galactose-1-phosphate uridylyltransferase
FE240_RS16745	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FE240_RS16750	COG2017	converts alpha-aldose to the beta-anomer
FE240_RS16755	COG1968	undecaprenyl-diphosphatase activity
FE240_RS16760	COG0561	phosphatase activity
FE240_RS16785	COG1309	transcriptional regulator
FE240_RS16790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_RS16795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE240_RS16800	COG3245	cytochrome
FE240_RS16805	COG3706	GGDEF domain
FE240_RS16805	COG5001	Diguanylate cyclase
FE240_RS16805	COG2203	Gaf domain
FE240_RS16805	COG4251	negative regulation of phosphorylation
FE240_RS16810	COG0210	DNA helicase
FE240_RS16815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FE240_RS16820	COG2166	iron-sulfur cluster assembly
FE240_RS16830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FE240_RS16835	COG1368	sulfuric ester hydrolase activity
FE240_RS16840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FE240_RS16845	COG3706	GGDEF domain
FE240_RS16850	COG3263	regulation of cellular component size
FE240_RS16855	COG0484	heat shock protein binding
FE240_RS16875	COG1671	Belongs to the UPF0178 family
FE240_RS16885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FE240_RS16895	COG1494	fructose-1,6-bisphosphatase
FE240_RS16905	COG0288	reversible hydration of carbon dioxide
FE240_RS16915	COG2177	Part of the ABC transporter FtsEX involved in
FE240_RS16920	COG2884	Cell division ATP-binding protein ftsE
FE240_RS16925	COG0552	protein localization to endoplasmic reticulum
FE240_RS16930	COG0742	ribosomal rna small subunit methyltransferase
FE240_RS16950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE240_RS16965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE240_RS16975	COG2095	MarC family integral membrane protein
FE240_RS16985	COG1301	dicarboxylic acid transport
FE240_RS16995	COG0583	DNA-binding transcription factor activity
FE240_RS17020	COG0203	ribosomal protein L17
FE240_RS17025	COG0202	RNA polymerase activity
FE240_RS17030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FE240_RS17035	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FE240_RS17040	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FE240_RS17045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FE240_RS17050	COG0201	protein transport
FE240_RS17055	COG0200	Binds to the 23S rRNA
FE240_RS17060	COG1841	ribosomal large subunit assembly
FE240_RS17065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FE240_RS17070	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FE240_RS17075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FE240_RS17080	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FE240_RS17085	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FE240_RS17090	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FE240_RS17095	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FE240_RS17100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FE240_RS17105	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FE240_RS17110	COG0255	Belongs to the universal ribosomal protein uL29 family
FE240_RS17115	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FE240_RS17120	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FE240_RS17125	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FE240_RS17130	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FE240_RS17135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FE240_RS17140	COG0089	rRNA binding
FE240_RS17145	COG0088	Forms part of the polypeptide exit tunnel
FE240_RS17150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FE240_RS17155	COG0051	transcription antitermination factor activity, RNA binding
FE240_RS17175	COG0165	Argininosuccinate lyase
FE240_RS17180	COG0137	argininosuccinate synthase activity
FE240_RS17190	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FE240_RS17195	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FE240_RS17205	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FE240_RS17235	COG1380	Effector of murein hydrolase LrgA
FE240_RS17240	COG1346	cytolysis
FE240_RS17250	COG0583	DNA-binding transcription factor activity
FE240_RS17255	COG0460	homoserine dehydrogenase
FE240_RS17255	COG0527	aspartate kinase activity
FE240_RS17260	COG0626	cystathionine gamma-synthase activity
FE240_RS17270	COG0814	amino acid
FE240_RS17280	COG2358	TRAP transporter, solute receptor (TAXI family
FE240_RS17285	COG2885	chlorophyll binding
FE240_RS17295	COG2818	Glycosylase
FE240_RS17300	COG0752	glycyl-tRNA synthetase alpha subunit
FE240_RS17305	COG0751	glycine-tRNA ligase activity
FE240_RS17320	COG0814	amino acid
FE240_RS17325	COG0348	domain, Protein
FE240_RS17330	COG2226	methyltransferase
FE240_RS17330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE240_RS17330	COG0596	Alpha beta hydrolase
FE240_RS17340	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE240_RS17345	COG1773	rubredoxin
FE240_RS17345	COG0426	domain, Protein
FE240_RS17350	COG3604	Transcriptional regulator
FE240_RS17355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FE240_RS17375	COG0683	leucine binding
FE240_RS17410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FE240_RS17420	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FE240_RS17430	COG1580	Controls the rotational direction of flagella during chemotaxis
FE240_RS17445	COG1519	Transferase
FE240_RS17450	COG0859	PFAM glycosyl transferase family 9
FE240_RS17485	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FE240_RS17490	COG0848	biopolymer transport protein
FE240_RS17495	COG0811	peptide transport
FE240_RS17500	COG0811	peptide transport
FE240_RS17510	COG2771	luxR family
FE240_RS17565	COG2205	protein histidine kinase activity
FE240_RS17570	COG0745	RESPONSE REGULATOR receiver
FE240_RS17580	COG3977	Valine--pyruvate aminotransferase
FE240_RS17585	COG0071	Belongs to the small heat shock protein (HSP20) family
FE240_RS17605	COG0592	DNA-directed DNA polymerase activity
FE240_RS17610	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FE240_RS17625	COG1126	abc transporter atp-binding protein
FE240_RS17630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FE240_RS17635	COG0594	ribonuclease P activity
FE240_RS17640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FE240_RS17645	COG0706	membrane insertase activity
FE240_RS17650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FE240_RS17655	COG4974	Belongs to the 'phage' integrase family
FE240_RS17690	COG3012	SEC-C Motif Domain Protein
FE240_RS17690	COG3318	Belongs to the UPF0149 family
FE240_RS17700	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FE240_RS17735	COG3550	peptidyl-serine autophosphorylation
FE240_RS17745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FE240_RS17750	COG1120	ATPase activity
FE240_RS17755	COG4615	Cyclic peptide transporter
FE240_RS17760	COG4774	siderophore transport
FE240_RS17765	COG0716	FMN binding
FE240_RS17770	COG0445	tRNA wobble uridine modification
FE240_RS17775	COG0357	Ribosomal RNA small subunit methyltransferase G
FE240_RS17780	COG1192	Involved in chromosome partitioning
FE240_RS17785	COG1475	DNA binding
FE240_RS17795	COG0356	it plays a direct role in the translocation of protons across the membrane
FE240_RS17805	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FE240_RS17810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FE240_RS17815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FE240_RS17820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FE240_RS17825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FE240_RS17830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FE240_RS17835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FE240_RS17850	COG1902	pentaerythritol trinitrate reductase activity
FE240_RS17895	COG1196	nuclear chromosome segregation
FE240_RS17965	COG3093	addiction module antidote protein HigA
FE240_RS17970	COG3549	Plasmid maintenance system killer
FE240_RS17980	COG1561	YicC-like family, N-terminal region
FE240_RS17990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FE240_RS17995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FE240_RS18005	COG0248	Ppx GppA phosphatase
FE240_RS18010	COG0513	Belongs to the DEAD box helicase family
FE240_RS18015	COG3118	belongs to the thioredoxin family
FE240_RS18030	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FE240_RS18040	COG5001	Diguanylate cyclase
FE240_RS18045	COG2960	long-chain fatty acid transporting porin activity
FE240_RS18055	COG0668	transmembrane transport
FE240_RS18060	COG1309	transcriptional regulator
FE240_RS18065	COG0756	dUTP diphosphatase activity
FE240_RS18070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FE240_RS18075	COG2003	Belongs to the UPF0758 family
FE240_RS18080	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FE240_RS18085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FE240_RS18095	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FE240_RS18100	COG2990	Protein conserved in bacteria
FE240_RS18105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FE240_RS18110	COG0859	PFAM glycosyl transferase family 9
FE240_RS18115	COG0463	Glycosyl transferase, family 2
FE240_RS18120	COG0366	Alpha amylase catalytic
FE240_RS18135	COG0443	Heat shock 70 kDa protein
FE240_RS18140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FE240_RS18150	COG3045	CreA protein
FE240_RS18170	COG0174	glutamine synthetase
FE240_RS18190	COG3842	ATPase activity
FE240_RS18195	COG1176	ABC-type spermidine putrescine transport system, permease component I
FE240_RS18200	COG1177	transmembrane transport
FE240_RS18205	COG2258	MOSC domain
FE240_RS18230	COG2249	NAD(P)H dehydrogenase (quinone) activity
FE240_RS18245	COG1770	oligopeptidase
FE240_RS18250	COG0251	oxidation-reduction process
FE240_RS18255	COG0425	Belongs to the sulfur carrier protein TusA family
FE240_RS18275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FE240_RS18280	COG0385	Bile acid
FE240_RS18290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE240_RS18295	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE240_RS18330	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FE240_RS18345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FE240_RS18350	COG0254	rRNA binding
FE240_RS18355	COG0702	epimerase
FE240_RS18360	COG0281	malic enzyme
FE240_RS18365	COG2205	protein histidine kinase activity
FE240_RS18370	COG0745	RESPONSE REGULATOR receiver
FE240_RS18390	COG0183	Belongs to the thiolase family
FE240_RS18395	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE240_RS18395	COG1024	Enoyl-CoA hydratase
FE240_RS18400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE240_RS18405	COG0006	proline dipeptidase activity
FE240_RS18410	COG1739	Uncharacterized protein family UPF0029
FE240_RS18415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FE240_RS18420	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FE240_RS18470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FE240_RS18475	COG1288	antiporter activity
FE240_RS18495	COG3706	GGDEF domain
FE240_RS18510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FE240_RS18515	COG0569	domain protein
FE240_RS18520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FE240_RS18530	COG2056	Na+-H+ antiporter family
FE240_RS18535	COG1072	(Pantothenic acid kinase))
FE240_RS18555	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FE240_RS18570	COG0250	Participates in transcription elongation, termination and antitermination
FE240_RS18575	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FE240_RS18580	COG0081	regulation of translation
FE240_RS18585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FE240_RS18590	COG0222	ribosome binding
FE240_RS18595	COG0085	RNA polymerase activity
FE240_RS18600	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FE240_RS18605	COG2964	Protein conserved in bacteria
FE240_RS18610	COG0251	oxidation-reduction process
FE240_RS18620	COG2923	Belongs to the DsrF TusC family
FE240_RS18625	COG2168	tRNA wobble position uridine thiolation
FE240_RS18630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FE240_RS18635	COG0049	tRNA binding
FE240_RS18640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FE240_RS18645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FE240_RS18650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FE240_RS18685	COG0402	S-adenosylhomocysteine deaminase activity
FE240_RS18690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FE240_RS18700	COG3165	ubiquinone biosynthetic process from chorismate
FE240_RS18705	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FE240_RS18715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE240_RS18720	COG0805	protein transport
FE240_RS18725	COG0084	hydrolase, TatD family'
FE240_RS18735	COG1196	nuclear chromosome segregation
FE240_RS18775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE240_RS18785	COG0339	signal peptide processing
FE240_RS18795	COG0742	ribosomal rna small subunit methyltransferase
FE240_RS18810	COG2937	Belongs to the GPAT DAPAT family
FE240_RS18815	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FE240_RS18825	COG0534	Mate efflux family protein
FE240_RS18830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FE240_RS18835	COG2205	protein histidine kinase activity
FE240_RS18840	COG0745	RESPONSE REGULATOR receiver
FE240_RS18850	COG1045	serine acetyltransferase
FE240_RS18860	COG3074	FtsZ-dependent cytokinesis
FE240_RS18865	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FE240_RS18870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE240_RS18870	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE240_RS18875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily