locus-tag	class	description
E5E97_RS00010	ENOG4105CMQ	Chloride channel
E5E97_RS00015	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
E5E97_RS00030	ENOG41076MN	Phosphoesterase, PA-phosphatase related
E5E97_RS00040	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E97_RS00050	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
E5E97_RS00055	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
E5E97_RS00060	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
E5E97_RS00070	ENOG4105CQ7	ATP-dependent helicase
E5E97_RS00080	ENOG4105PW4	Sugar fermentation stimulation protein homolog
E5E97_RS00090	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
E5E97_RS00095	ENOG4105DJ0	Poly(A) Polymerase
E5E97_RS00100	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5E97_RS00105	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
E5E97_RS00110	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
E5E97_RS00130	ENOG4105CIZ	coA-substrate-specific enzyme activase
E5E97_RS00135	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
E5E97_RS00140	ENOG4105E3A	(ABC) transporter
E5E97_RS00145	ENOG4105DA5	(ABC) transporter
E5E97_RS00150	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E5E97_RS00155	ENOG410630P	Transcriptional regulator
E5E97_RS00160	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E5E97_RS00165	ENOG4105DFU	Cell wall formation (By similarity)
E5E97_RS00170	ENOG4105F0N	pyrophosphate phospho-hydrolase
E5E97_RS00185	ENOG4108UUE	Transcriptional regulator
E5E97_RS00200	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E5E97_RS00220	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E5E97_RS00235	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
E5E97_RS00245	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
E5E97_RS00250	ENOG4105C11	sulfate adenylyltransferase), subunit 2
E5E97_RS00255	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E5E97_RS00260	ENOG4107QX8	SPFH domain, Band 7 family protein
E5E97_RS00265	ENOG4105G5H	Membrane
E5E97_RS00270	ENOG4105C2X	Arabinose 5-phosphate isomerase
E5E97_RS00275	ENOG4105C5H	ABC transporter
E5E97_RS00285	ENOG4105D6S	protein involved in catabolism of external DNA
E5E97_RS00290	ENOG4105EQ2	LysR family Transcriptional regulator
E5E97_RS00330	ENOG4105CK7	Sodium proline symporter
E5E97_RS00335	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E5E97_RS00340	ENOG4105CUY	Mechanosensitive ion channel
E5E97_RS00350	ENOG4105XEP	YhcH YjgK YiaL family protein
E5E97_RS00380	ENOG4107SQD	Transcriptional regulator, GntR family
E5E97_RS00405	ENOG4105C8J	)-transporter
E5E97_RS00415	ENOG4105C8J	)-transporter
E5E97_RS00430	ENOG4108K4B	hydrolase
E5E97_RS00450	ENOG4105EW9	transcriptional regulator AsnC family
E5E97_RS00465	ENOG4105K56	Transcriptional regulator
E5E97_RS00470	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E5E97_RS00475	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
E5E97_RS00480	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E5E97_RS00490	ENOG4105E0X	reductase
E5E97_RS00500	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E5E97_RS00505	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
E5E97_RS00515	ENOG4105DSB	aldose 1-epimerase
E5E97_RS00520	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E5E97_RS00525	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS00600	ENOG4105UFD	tol-pal system protein YbgF
E5E97_RS00605	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E5E97_RS00610	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E5E97_RS00620	ENOG4105M8F	Biopolymer transport protein exbD tolR
E5E97_RS00625	ENOG4105E02	MotA TolQ exbB proton channel
E5E97_RS00630	ENOG4107YD3	Thioesterase
E5E97_RS00635	ENOG4105KJB	cyd operon protein YbgE
E5E97_RS00645	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E5E97_RS00650	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E5E97_RS00660	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E5E97_RS00665	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS00670	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E5E97_RS00675	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
E5E97_RS00690	ENOG4105E39	Enoyl-CoA hydratase
E5E97_RS00695	ENOG4106WH9	Protein of unknown function (DUF2753)
E5E97_RS00700	ENOG4105EQK	-acetyltransferase
E5E97_RS00710	ENOG4107QSI	ABC, transporter
E5E97_RS00725	ENOG4105VZ9	UPF0235 protein
E5E97_RS00730	ENOG4108VIA	integral membrane protein
E5E97_RS00735	ENOG4105II7	pyrroline-5-carboxylate reductase
E5E97_RS00740	ENOG4105DFA	alanine racemase domain protein
E5E97_RS00745	ENOG4105CZX	twitching motility protein
E5E97_RS00750	ENOG4105CZX	twitching motility protein
E5E97_RS00755	ENOG4105D1Q	UPF0246 protein
E5E97_RS00760	ENOG4105C1J	atp-dependent rna helicase
E5E97_RS00765	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
E5E97_RS00770	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E5E97_RS00775	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E5E97_RS00790	ENOG4105MYN	Zinc uptake regulation protein
E5E97_RS00795	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E5E97_RS00810	ENOG4105K70	DNA-binding protein
E5E97_RS00820	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
E5E97_RS00830	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E5E97_RS00845	ENOG4105EAC	phosphoserine phosphatase
E5E97_RS00855	ENOG4105BZU	Histidine kinase
E5E97_RS00860	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
E5E97_RS00865	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
E5E97_RS00870	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
E5E97_RS00875	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
E5E97_RS00885	ENOG4105D9N	nucleoside
E5E97_RS00890	ENOG4105EYA	deoxyribonuclease
E5E97_RS00905	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E5E97_RS00910	ENOG4105BZU	Histidine kinase
E5E97_RS01000	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E5E97_RS01010	ENOG4108KU3	Integrase
E5E97_RS01020	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5E97_RS01030	ENOG4105M7P	phage repressor
E5E97_RS01100	ENOG4105ED4	portal protein
E5E97_RS01150	ENOG4105KSC	Transcriptional regulator, TraR DksA family
E5E97_RS01225	ENOG4108K5H	permease YjgP YjgQ family protein
E5E97_RS01230	ENOG4108M8S	permease YjgP YjgQ family protein
E5E97_RS01235	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E5E97_RS01240	ENOG4105MYG	DNA polymerase iii, chi subunit
E5E97_RS01255	ENOG4106W5V	Membrane
E5E97_RS01260	ENOG41061WM	D-Alanyl-D-Alanine
E5E97_RS01295	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
E5E97_RS01300	ENOG4105CFH	Aspartokinase
E5E97_RS01305	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E5E97_RS01315	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E5E97_RS01320	ENOG4107TH8	cina domain protein
E5E97_RS01325	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E5E97_RS01345	ENOG4105R2J	Conserved Protein
E5E97_RS01355	ENOG4105DR5	peptidase
E5E97_RS01375	ENOG4105NXV	High-affinity zinc uptake system protein
E5E97_RS01380	ENOG4105FDK	ABC transporter
E5E97_RS01385	ENOG4105FAV	ABC, transporter
E5E97_RS01390	ENOG4105ETT	transcriptional Regulator, LysR family
E5E97_RS01400	ENOG4108RG0	uracil-dna glycosylase
E5E97_RS01405	ENOG4105FR1	rard protein
E5E97_RS01415	ENOG41082IR	Excinuclease ABC C subunit domain protein
E5E97_RS01430	ENOG41087YS	Phage shock protein A
E5E97_RS01435	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
E5E97_RS01460	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5E97_RS01465	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E5E97_RS01505	ENOG4107RRE	RNA-directed DNA polymerase
E5E97_RS01510	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5E97_RS01515	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5E97_RS01520	ENOG4105DSW	Fusaric acid resistance protein
E5E97_RS01525	ENOG4105Y49	secretion protein, HlyD family
E5E97_RS01545	ENOG4105IPS	esterase
E5E97_RS01550	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E5E97_RS01555	ENOG4108SX3	cytoplasmic protein
E5E97_RS01560	ENOG41087AY	ADP-Ribose pyrophosphatase
E5E97_RS01565	ENOG4105DFG	type I secretion outer membrane protein
E5E97_RS01570	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E5E97_RS01575	ENOG4105D1S	lipid A biosynthesis
E5E97_RS01590	ENOG4107IX6	phosphate transport regulator
E5E97_RS01595	ENOG4105CJ3	phosphate transporter
E5E97_RS01600	ENOG4108Z66	YbaK ebsC protein
E5E97_RS01605	ENOG41072TH	Protein of unknown function (DUF1479)
E5E97_RS01630	ENOG4105CMU	LysR family (Transcriptional regulator
E5E97_RS01640	ENOG41067MG	lrgb family
E5E97_RS01655	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
E5E97_RS01670	ENOG4105CEN	a g-specific adenine glycosylase
E5E97_RS01675	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
E5E97_RS01685	ENOG4105H4F	exported protein
E5E97_RS01700	ENOG4105UYK	outer membrane protein a
E5E97_RS01705	ENOG4108Q2G	(LipO)protein
E5E97_RS01710	ENOG4105DY2	Paraquat-inducible protein b
E5E97_RS01715	ENOG4105F1S	paraquat-inducible protein a
E5E97_RS01720	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E5E97_RS01725	ENOG4107VXZ	Hydrolase
E5E97_RS01740	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E5E97_RS01745	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
E5E97_RS01750	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E5E97_RS01755	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E5E97_RS01795	ENOG4105DFD	Na H antiporter
E5E97_RS01800	ENOG4108M0I	Transcriptional regulator
E5E97_RS01805	ENOG4107TYH	extracellular solute-binding protein family 1
E5E97_RS01810	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E5E97_RS01815	ENOG4105D81	ABC transporter, permease
E5E97_RS01820	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
E5E97_RS01825	ENOG4105C26	Dehydrogenase
E5E97_RS01835	ENOG4107AQZ	Membrane
E5E97_RS01845	ENOG4108UW5	maltose o-acetyltransferase
E5E97_RS01850	ENOG4105CG3	alpha amylase, catalytic region
E5E97_RS01855	ENOG4105C5Y	PTS System
E5E97_RS01860	ENOG4105D4X	repressor
E5E97_RS01875	ENOG4105HDK	L-asparaginase
E5E97_RS01890	ENOG4108Z5K	methylglyoxal synthase
E5E97_RS01900	ENOG4108UQY	Iron-storage protein
E5E97_RS01915	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
E5E97_RS01925	ENOG4107R88	Chemotaxis protein (CheV)
E5E97_RS01970	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
E5E97_RS01975	ENOG4107ZVW	dihydroneopterin aldolase
E5E97_RS01980	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5E97_RS01990	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E5E97_RS01995	ENOG4105CKI	cobalamin synthesis protein
E5E97_RS02005	ENOG4105E82	cytochrome subunit of dehydrogenase
E5E97_RS02015	ENOG4105BZU	Histidine kinase
E5E97_RS02020	ENOG4107QIJ	Aconitate hydratase 2
E5E97_RS02030	ENOG4108N3W	hemolysin secretion protein
E5E97_RS02035	ENOG4108N3W	hemolysin secretion protein
E5E97_RS02045	ENOG4107QN2	dihydrolipoyl dehydrogenase
E5E97_RS02050	ENOG4107QSN	dihydrolipoamide acetyltransferase
E5E97_RS02055	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E5E97_RS02060	ENOG41073TP	transcriptional regulator
E5E97_RS02075	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E5E97_RS02090	ENOG4105D7Q	type ii secretion system
E5E97_RS02105	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
E5E97_RS02110	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
E5E97_RS02115	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E5E97_RS02125	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E5E97_RS02135	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5E97_RS02140	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E5E97_RS02145	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E5E97_RS02150	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
E5E97_RS02155	ENOG4105DFU	Cell wall formation (By similarity)
E5E97_RS02160	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E5E97_RS02165	ENOG4105CNI	cell division protein FtsW
E5E97_RS02170	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E5E97_RS02175	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E5E97_RS02180	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E5E97_RS02185	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E5E97_RS02190	ENOG4105CJN	penicillin-binding protein
E5E97_RS02195	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E5E97_RS02200	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E5E97_RS02205	ENOG4108V6E	Cell division protein mraZ
E5E97_RS02215	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E5E97_RS02220	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
E5E97_RS02225	ENOG41082RQ	UPF0102 protein
E5E97_RS02230	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E5E97_RS02235	ENOG4105W4M	Transport-associated protein
E5E97_RS02240	ENOG4105KB2	stringent starvation protein b
E5E97_RS02245	ENOG4107MKT	Stringent starvation protein a
E5E97_RS02250	ENOG4105EIX	cytochrome c1
E5E97_RS02255	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E5E97_RS02260	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E5E97_RS02265	ENOG4108UJD	30S ribosomal protein S9
E5E97_RS02270	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E5E97_RS02275	ENOG4105D6Z	AFG1 family ATPase
E5E97_RS02285	ENOG4105C0H	protease
E5E97_RS02290	ENOG4105C0H	protease
E5E97_RS02320	ENOG41069H0	dihydroorotase EC 3.5.2.3
E5E97_RS02340	ENOG41080Z8	PHOSPHOCARRIER protein
E5E97_RS02345	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E5E97_RS02350	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
E5E97_RS02355	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
E5E97_RS02360	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5E97_RS02365	ENOG4108IUZ	ABC transporter
E5E97_RS02370	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
E5E97_RS02375	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
E5E97_RS02385	ENOG4105C2X	Arabinose 5-phosphate isomerase
E5E97_RS02390	ENOG4105DHJ	ABC, transporter
E5E97_RS02395	ENOG4105CY3	ABC transporter, permease
E5E97_RS02400	ENOG4107PE3	Mammalian cell entry related domain protein
E5E97_RS02405	ENOG4105E3I	toluene tolerance
E5E97_RS02415	ENOG4105VFK	BolA family
E5E97_RS02420	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E5E97_RS02425	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
E5E97_RS02430	ENOG4105N42	UPF0307 protein
E5E97_RS02440	ENOG41090HJ	UPF0265 protein
E5E97_RS02470	ENOG4108JCI	Transcriptional regulator
E5E97_RS02475	ENOG4105DKK	Benzoate
E5E97_RS02485	ENOG4105SYT	Methylenetetrahydrofolate reductase
E5E97_RS02500	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS02505	ENOG4105EIF	outer membrane protein W
E5E97_RS02510	ENOG4105BZU	Histidine kinase
E5E97_RS02515	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E5E97_RS02520	ENOG41086KC	Transcriptional regulator
E5E97_RS02525	ENOG4108UUM	single-stranded DNA-binding protein
E5E97_RS02535	ENOG41076HS	cation diffusion facilitator family transporter
E5E97_RS02545	ENOG4105VEQ	Cold shock protein
E5E97_RS02550	ENOG4105D05	Receptor
E5E97_RS02560	ENOG4105E0F	Histidine kinase
E5E97_RS02590	ENOG4105BZU	Histidine kinase
E5E97_RS02600	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
E5E97_RS02620	ENOG4107QYX	exodeoxyribonuclease v alpha
E5E97_RS02625	ENOG4107QKA	exodeoxyribonuclease V beta
E5E97_RS02630	ENOG4105DSY	exodeoxyribonuclease V, gamma
E5E97_RS02635	ENOG4108VBZ	doxx family
E5E97_RS02640	ENOG4105C2I	pirin domain protein
E5E97_RS02650	ENOG4105CWB	LysR family transcriptional Regulator
E5E97_RS02675	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
E5E97_RS02685	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E5E97_RS02715	ENOG4105WCN	acetyltransferase
E5E97_RS02720	ENOG4105CH6	catalase
E5E97_RS02750	ENOG4105IPI	Membrane
E5E97_RS02755	ENOG4105EMU	Dehydrogenase
E5E97_RS02760	ENOG4105DWY	Agmatine deiminase
E5E97_RS02765	ENOG4105ETT	transcriptional Regulator, LysR family
E5E97_RS02770	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
E5E97_RS02785	ENOG4108UTZ	Dihydroxyacetone kinase
E5E97_RS02790	ENOG4105CMT	Dihydroxyacetone kinase
E5E97_RS02795	ENOG4105C7N	Xanthine uracil vitamin C permease
E5E97_RS02830	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
E5E97_RS02835	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E5E97_RS02840	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E5E97_RS02845	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
E5E97_RS02850	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E5E97_RS02855	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E5E97_RS02860	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E5E97_RS02870	ENOG4105KME	endoribonuclease L-psp
E5E97_RS02875	ENOG4105WWK	YheO domain protein
E5E97_RS02880	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5E97_RS02885	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5E97_RS02890	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E5E97_RS02895	ENOG4108VZM	50s ribosomal protein L10
E5E97_RS02900	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E5E97_RS02905	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E5E97_RS02910	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E5E97_RS02915	ENOG4105PM1	preprotein translocase subunit SecE
E5E97_RS02925	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E5E97_RS02940	ENOG4105CS9	pantothenic acid kinase
E5E97_RS02945	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
E5E97_RS02950	ENOG4105D4A	Cell wall formation (By similarity)
E5E97_RS02955	ENOG4107ZYR	domain protein
E5E97_RS02965	ENOG4105E7U	AraC family transcriptional regulator
E5E97_RS02980	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E5E97_RS02985	ENOG4105CUW	cytochrome C-TYPE protein
E5E97_RS02990	ENOG4107QY8	reductase
E5E97_RS03000	ENOG4105IFJ	Histidine kinase
E5E97_RS03005	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E5E97_RS03020	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
E5E97_RS03030	ENOG4108UQ5	membrane protein YcdZ
E5E97_RS03035	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5E97_RS03045	ENOG4107WP9	Histidine kinase
E5E97_RS03060	ENOG410642E	Short chain dehydrogenase
E5E97_RS03065	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E5E97_RS03080	ENOG4108VVK	transcriptional Regulator, AsnC
E5E97_RS03085	ENOG4105CU9	asparagine synthetase A
E5E97_RS03090	ENOG4107T8T	UPF0173 metal-dependent hydrolase
E5E97_RS03095	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5E97_RS03100	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E5E97_RS03105	ENOG4105C34	Pseudouridine synthase
E5E97_RS03110	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5E97_RS03115	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
E5E97_RS03125	ENOG4105CEM	UPF0597 protein
E5E97_RS03135	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E5E97_RS03140	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E5E97_RS03145	ENOG4108I6A	alcohol dehydrogenase
E5E97_RS03150	ENOG4105CF7	AraC family transcriptional regulator
E5E97_RS03155	ENOG4105QNF	Outer membrane lipoprotein
E5E97_RS03160	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS03165	ENOG4105DJ4	phosphatidylserine decarboxylase
E5E97_RS03185	ENOG4105CXT	aspartate transcarbamylase
E5E97_RS03190	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
E5E97_RS03195	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
E5E97_RS03200	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
E5E97_RS03205	ENOG4105DBV	ornithine carbamoyltransferase
E5E97_RS03210	ENOG4105C5B	carbamate kinase
E5E97_RS03235	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS03240	ENOG4107SDZ	Galactoside transport system permease protein mglC
E5E97_RS03245	ENOG4105C2J	ABC transporter
E5E97_RS03255	ENOG4105CNT	hydrolase family 2
E5E97_RS03260	ENOG41060NJ	transcriptional regulator
E5E97_RS03265	ENOG4105CMR	udp-glucose 4-epimerase
E5E97_RS03270	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
E5E97_RS03275	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
E5E97_RS03280	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
E5E97_RS03285	ENOG4105CPC	Aldo Keto reductase
E5E97_RS03290	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E5E97_RS03295	ENOG4108NIX	Factor ChrR
E5E97_RS03300	ENOG4105K6V	RNA polymerase
E5E97_RS03310	ENOG4105C75	arginyL-tRNA synthetase
E5E97_RS03320	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
E5E97_RS03325	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
E5E97_RS03330	ENOG4105C57	major facilitator superfamily
E5E97_RS03340	ENOG4107QZF	nitrite reductase NADPH large subunit
E5E97_RS03345	ENOG4105WZK	nitrite reductase NADPH small subunit
E5E97_RS03350	ENOG4107V9H	nitrite transporter
E5E97_RS03355	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E5E97_RS03365	ENOG4108NVR	Methyl-accepting chemotaxis
E5E97_RS03370	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E5E97_RS03375	ENOG4105EX9	Membrane
E5E97_RS03385	ENOG4105CNG	UPF0061 protein
E5E97_RS03390	ENOG4105N7H	Cytochrome
E5E97_RS03395	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E5E97_RS03400	ENOG4108VUY	thioesterase Superfamily protein
E5E97_RS03415	ENOG4108RPX	mosc domain containing protein
E5E97_RS03420	ENOG4105D38	putrescine abc transporter
E5E97_RS03425	ENOG4105F38	ABC transporter, permease
E5E97_RS03430	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E5E97_RS03435	ENOG4108HM4	ABC transporter
E5E97_RS03445	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E5E97_RS03450	ENOG4105CFQ	glutamine synthetase
E5E97_RS03455	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E5E97_RS03470	ENOG4108RH0	Crea protein
E5E97_RS03475	ENOG4105C5I	Dehydrogenase
E5E97_RS03480	ENOG4105R8A	Heat shock protein
E5E97_RS03495	ENOG4107R28	alpha amylase, catalytic region
E5E97_RS03500	ENOG4105C5E	polysaccharide biosynthesis protein
E5E97_RS03505	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E5E97_RS03535	ENOG4105K64	Glycosyl transferase, family 2
E5E97_RS03545	ENOG4105X1N	Glycosyl transferase family 8
E5E97_RS03550	ENOG4105CND	Glycosyl transferase, family 2
E5E97_RS03565	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E97_RS03570	ENOG4105CHR	reductase
E5E97_RS03585	ENOG4105F0R	Cytidylyltransferase
E5E97_RS03595	ENOG4105D2T	synthase
E5E97_RS03615	ENOG4105EQQ	protein containing aminopeptidase domain
E5E97_RS03650	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
E5E97_RS03655	ENOG4107EXC	regulatoR
E5E97_RS03660	ENOG4105JJR	Histidine kinase
E5E97_RS03670	ENOG4105C6K	Malic enzyme
E5E97_RS03675	ENOG4105CGD	Nad-dependent epimerase dehydratase
E5E97_RS03680	ENOG4105VFB	Binds the 23S rRNA (By similarity)
E5E97_RS03685	ENOG4105C25	Primosomal protein n'
E5E97_RS03695	ENOG4105UYK	outer membrane protein a
E5E97_RS03700	ENOG4105C7B	Threonine dehydratase
E5E97_RS03705	ENOG4105C01	Dihydroxy-acid dehydratase
E5E97_RS03710	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E5E97_RS03715	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
E5E97_RS03725	ENOG4105C0P	Mg chelatase subunit ChlI
E5E97_RS03730	ENOG4106HNH	Acyl-transferase
E5E97_RS03735	ENOG4106HNH	Acyl-transferase
E5E97_RS03740	ENOG4105EWC	Purine nucleoside phosphorylase
E5E97_RS03750	ENOG4108RWI	nicotinamidase
E5E97_RS03755	ENOG4107RH7	Nicotinate phosphoribosyltransferase
E5E97_RS03760	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
E5E97_RS03765	ENOG4108VA1	ABC transporter
E5E97_RS03770	ENOG4105S7S	phosphonate abc transporter
E5E97_RS03775	ENOG4108Z33	Thiol disulfide Interchange Protein
E5E97_RS03780	ENOG4105E27	serine threonine protein kinase
E5E97_RS03790	ENOG4105PC1	Conserved Protein
E5E97_RS03810	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E5E97_RS03815	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
E5E97_RS03820	ENOG4105DSJ	YicC domain protein
E5E97_RS03840	ENOG4105W1T	Glycosyl Transferase
E5E97_RS03855	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
E5E97_RS03860	ENOG41062JF	Transcriptional regulator
E5E97_RS03865	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E5E97_RS03870	ENOG4105CPQ	Dehydrogenase
E5E97_RS03875	ENOG4105MPD	Cytochrome
E5E97_RS03880	ENOG4105BZU	Histidine kinase
E5E97_RS03885	ENOG4105C4R	Atp-dependent dna helicase
E5E97_RS03890	ENOG4105C9B	Cysteine desulfurase
E5E97_RS03895	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
E5E97_RS03900	ENOG4105CUZ	uba thif-type nad fad binding protein
E5E97_RS03935	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E5E97_RS03940	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E5E97_RS03945	ENOG41063Z6	transcriptional regulator, lysR family
E5E97_RS03960	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E5E97_RS03965	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E5E97_RS03970	ENOG4105FCD	Major Facilitator
E5E97_RS03975	ENOG4105DY9	regulatoR
E5E97_RS03980	ENOG4108HRK	Histidine kinase
E5E97_RS03995	ENOG4107ZHV	Transcriptional regulator
E5E97_RS04000	ENOG4108GWT	fimbrillin MatB
E5E97_RS04005	ENOG4108NN8	Fimbrial protein
E5E97_RS04010	ENOG4108N3D	putative enzyme
E5E97_RS04030	ENOG4105EU0	Major facilitator Superfamily
E5E97_RS04035	ENOG4105CBX	hi0933 family
E5E97_RS04040	ENOG41090A1	ferritin
E5E97_RS04045	ENOG4105BZU	Histidine kinase
E5E97_RS04050	ENOG4105RKW	reductase (By
E5E97_RS04055	ENOG4108M6U	Universal stress protein A
E5E97_RS04085	ENOG4105EMK	carboxylate amino acid amine transporter
E5E97_RS04095	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
E5E97_RS04100	ENOG4105DKP	glycosyl transferase, family 9
E5E97_RS04110	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E5E97_RS04115	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E5E97_RS04120	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
E5E97_RS04125	ENOG4108EUD	Lysophospholipase
E5E97_RS04130	ENOG4105DQF	Hydrolase
E5E97_RS04140	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
E5E97_RS04150	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
E5E97_RS04155	ENOG4105CXY	transporter
E5E97_RS04160	ENOG4105CA9	Pyruvate kinase
E5E97_RS04190	ENOG4105Y7M	Transcriptional regulator, TetR family
E5E97_RS04195	ENOG410624X	efflux transporter, rnd family, mfp subunit
E5E97_RS04200	ENOG4105BZS	acriflavin resistance protein
E5E97_RS04205	ENOG4105BZU	Histidine kinase
E5E97_RS04210	ENOG4105DC8	reductase
E5E97_RS04215	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E5E97_RS04220	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E5E97_RS04225	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
E5E97_RS04230	ENOG4105C08	Histidine kinase
E5E97_RS04235	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
E5E97_RS04240	ENOG4105C2C	drug resistance transporter, Bcr CflA
E5E97_RS04255	ENOG4105JKW	Valine--pyruvate aminotransferase
E5E97_RS04260	ENOG4108ZNX	Heat shock protein
E5E97_RS04265	ENOG4108ZNX	Heat shock protein
E5E97_RS04270	ENOG4105D29	Helix-turn-helix type 11 domain protein
E5E97_RS04280	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5E97_RS04285	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E5E97_RS04290	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E5E97_RS04295	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E5E97_RS04300	ENOG4105EAB	amino acid AbC transporter
E5E97_RS04305	ENOG4105E5Q	amino acid AbC transporter
E5E97_RS04310	ENOG4105CDA	abc transporter atp-binding protein
E5E97_RS04315	ENOG4105VG0	50S ribosomal protein l34
E5E97_RS04320	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E5E97_RS04325	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E5E97_RS04330	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E5E97_RS04335	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E5E97_RS04340	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
E5E97_RS04350	ENOG4105E0A	ABC, transporter
E5E97_RS04355	ENOG4105IBP	Cyclic peptide transporter
E5E97_RS04360	ENOG4105E0K	tonB-dependent siderophore receptor
E5E97_RS04365	ENOG4105QTB	Flavodoxin
E5E97_RS04370	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
E5E97_RS04375	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E5E97_RS04380	ENOG4107QJE	Chromosome Partitioning Protein
E5E97_RS04385	ENOG4105FA0	parb-like partition protein
E5E97_RS04395	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
E5E97_RS04400	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E5E97_RS04405	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E5E97_RS04410	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E5E97_RS04415	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
E5E97_RS04420	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
E5E97_RS04425	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E5E97_RS04430	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E5E97_RS04435	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E5E97_RS04440	ENOG4105CT7	inner membrane cred family protein
E5E97_RS04450	ENOG4105EB3	Histidine kinase
E5E97_RS04455	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E5E97_RS04460	ENOG410804X	Transcriptional regulator
E5E97_RS04465	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E5E97_RS04470	ENOG4105VJY	transcriptional regulator
E5E97_RS04490	ENOG4109015	Biopolymer transport protein exbD tolR
E5E97_RS04495	ENOG410822N	TonB family
E5E97_RS04540	ENOG4105DZC	cytosine deaminase
E5E97_RS04545	ENOG4105WMR	Protein CrcB homolog
E5E97_RS04555	ENOG4105JC1	sterol-binding domain protein
E5E97_RS04560	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
E5E97_RS04565	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E5E97_RS04570	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
E5E97_RS04575	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
E5E97_RS04580	ENOG4105F8V	Hydrolase, tatD family
E5E97_RS04585	ENOG4105D52	delta-aminolevulinic acid dehydratase
E5E97_RS04590	ENOG4105DGW	oligopeptidase A
E5E97_RS04595	ENOG4105BZU	Histidine kinase
E5E97_RS04600	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
E5E97_RS04615	ENOG4105C9X	ppx gppa phosphatase
E5E97_RS04620	ENOG4105C1J	atp-dependent rna helicase
E5E97_RS04630	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E5E97_RS04640	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E5E97_RS04645	ENOG4107QK7	reductase
E5E97_RS04650	ENOG4105W0Z	cytoplasmic protein
E5E97_RS04665	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
E5E97_RS04680	ENOG4108IV0	ABC, transporter
E5E97_RS04685	ENOG4105C0Z	ABC transporter
E5E97_RS04690	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
E5E97_RS04695	ENOG4105C32	Amino acid ABC transporter (Permease)
E5E97_RS04700	ENOG4105CP9	extracellular ligand-binding receptor
E5E97_RS04705	ENOG4105ETE	Transcriptional regulator (LacI family
E5E97_RS04710	ENOG4105F8D	glycoside hydrolase family 4
E5E97_RS04715	ENOG4105CI1	PTS System
E5E97_RS04720	ENOG4105FDP	GntR family transcriptional regulator
E5E97_RS04725	ENOG4108JUA	Transcriptional regulator
E5E97_RS04730	ENOG4105CNW	domain protein
E5E97_RS04745	ENOG4105HEE	Binding Domain protein
E5E97_RS04750	ENOG4105CIC	tryptophan-specific transport protein
E5E97_RS04765	ENOG41072JS	exoenzyme T
E5E97_RS04785	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
E5E97_RS04795	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E5E97_RS04800	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
E5E97_RS04805	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E5E97_RS04810	ENOG4105D3W	isochorismatase
E5E97_RS04815	ENOG4108ZG0	Ompa motb domain protein
E5E97_RS04820	ENOG4105M4H	endoribonuclease L-psp
E5E97_RS04825	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E5E97_RS04850	ENOG4105CHU	acetyl-coa acetyltransferase
E5E97_RS04855	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5E97_RS04860	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5E97_RS04865	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
E5E97_RS04870	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
E5E97_RS04875	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E5E97_RS04880	ENOG4108RR8	protoporphyrinogen oxidase
E5E97_RS04905	ENOG4105CD5	CoA-binding domain protein
E5E97_RS04920	ENOG4105EMY	transcriptional regulator
E5E97_RS04925	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E5E97_RS04930	ENOG4107QP8	phosphohexose isomerase
E5E97_RS04940	ENOG4105D64	Mechanosensitive ion channel
E5E97_RS04945	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
E5E97_RS04950	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E5E97_RS04955	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E5E97_RS04960	ENOG4105W5Q	DNA repair protein (RadC
E5E97_RS04965	ENOG4105KDC	50s ribosomal protein l28
E5E97_RS04970	ENOG4105W0E	50S ribosomal protein L33
E5E97_RS04980	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
E5E97_RS04985	ENOG4108MJ5	VirK protein
E5E97_RS04990	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E5E97_RS04995	ENOG4105M5K	heptosyltransferase
E5E97_RS05000	ENOG4106WTF	Glycosyl transferase, family 2
E5E97_RS05005	ENOG4105XA0	heptosyltransferase ii
E5E97_RS05010	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E5E97_RS05030	ENOG4105DIQ	Transcriptional regulator
E5E97_RS05035	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
E5E97_RS05055	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
E5E97_RS05060	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E5E97_RS05065	ENOG4105E55	glycerol-3-phosphate acyltransferase
E5E97_RS05070	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
E5E97_RS05085	ENOG4107R73	Mate efflux family protein
E5E97_RS05090	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E5E97_RS05095	ENOG4105E0F	Histidine kinase
E5E97_RS05100	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E5E97_RS05110	ENOG4105D7W	serine acetyltransferase
E5E97_RS05120	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
E5E97_RS05125	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
E5E97_RS05130	ENOG4105C2M	dna polymerase I
E5E97_RS05135	ENOG4108Z0R	Transferase
E5E97_RS05170	ENOG4105CQ4	Transcriptional regulator
E5E97_RS05175	ENOG4105CNT	hydrolase family 2
E5E97_RS05180	ENOG4105FK9	beta-D-galactosidase beta subunit
E5E97_RS05185	ENOG4105E5D	amino acid
E5E97_RS05190	ENOG4108Y51	tRNA-binding protein
E5E97_RS05195	ENOG4105E5D	amino acid
E5E97_RS05200	ENOG4105DHU	Bile acid
E5E97_RS05205	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
E5E97_RS05225	ENOG4105CC0	LysR family Transcriptional regulator
E5E97_RS05235	ENOG4105UIB	(ABC) transporter
E5E97_RS05240	ENOG4108JQ9	ABC transporter
E5E97_RS05245	ENOG4105DIH	basic membrane
E5E97_RS05250	ENOG4105C4R	Atp-dependent dna helicase
E5E97_RS05270	ENOG4105HEI	LysR family (Transcriptional regulator
E5E97_RS05290	ENOG41061EV	selenium-binding protein YdfZ
E5E97_RS05315	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
E5E97_RS05325	ENOG410829K	Lysine exporter protein (Lyse ygga)
E5E97_RS05335	ENOG4105CUC	YeeE YedE family protein
E5E97_RS05340	ENOG4108N3W	hemolysin secretion protein
E5E97_RS05345	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
E5E97_RS05350	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
E5E97_RS05355	ENOG4105ECQ	AraC Family Transcriptional Regulator
E5E97_RS05360	ENOG4105FR1	rard protein
E5E97_RS05370	ENOG4105C26	Dehydrogenase
E5E97_RS05375	ENOG4108JCI	Transcriptional regulator
E5E97_RS05385	ENOG4105C26	Dehydrogenase
E5E97_RS05390	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E5E97_RS05395	ENOG4105DCF	alanine dehydrogenase
E5E97_RS05400	ENOG4105D7K	pfkb domain protein
E5E97_RS05420	ENOG4105CGY	Dna recombination protein
E5E97_RS05425	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E5E97_RS05430	ENOG4105C1A	potassium transporter peripheral membrane
E5E97_RS05435	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E5E97_RS05440	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E5E97_RS05445	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E5E97_RS05455	ENOG4105C79	DNA protecting protein DprA
E5E97_RS05460	ENOG4108RPN	Protein smg homolog
E5E97_RS05465	ENOG4108WI1	Dna topoisomerase
E5E97_RS05480	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E5E97_RS05485	ENOG4105E2X	shikimate dehydrogenase
E5E97_RS05490	ENOG4105SG3	Protein of unknown function (DUF1488)
E5E97_RS05495	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
E5E97_RS05500	ENOG4106RE7	Cytochrome
E5E97_RS05505	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
E5E97_RS05510	ENOG4105XCT	Protein of unknown function (DUF2489)
E5E97_RS05515	ENOG4105D4P	Coproporphyrinogen iii oxidase
E5E97_RS05520	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E5E97_RS05525	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5E97_RS05530	ENOG4105CUX	Signal transduction histidine kinase
E5E97_RS05540	ENOG4105C5F	glutamine synthetase
E5E97_RS05545	ENOG4105CI3	gtp-binding protein typa
E5E97_RS05550	ENOG4107S2Z	UPF0761 membrane protein
E5E97_RS05555	ENOG4107S2Z	UPF0761 membrane protein
E5E97_RS05560	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
E5E97_RS05570	ENOG4105SUU	thioesterase domain
E5E97_RS05580	ENOG4105CB5	ATP-dependent DNA helicase recG
E5E97_RS05585	ENOG4105JIM	Phosphatidylserine synthase
E5E97_RS05590	ENOG4105C6Z	Gluconate
E5E97_RS05595	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
E5E97_RS05600	ENOG4105C01	Dihydroxy-acid dehydratase
E5E97_RS05605	ENOG4108UHU	Aldolase
E5E97_RS05610	ENOG4105DIQ	Transcriptional regulator
E5E97_RS05620	ENOG41063SB	peptidase
E5E97_RS05625	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E5E97_RS05630	ENOG4107YZP	Rhodanese domain protein
E5E97_RS05635	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
E5E97_RS05640	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
E5E97_RS05645	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
E5E97_RS05650	ENOG4105MJ2	Competence protein
E5E97_RS05660	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E5E97_RS05680	ENOG4105BZM	domain protein
E5E97_RS05685	ENOG4108RRZ	Transcription elongation factor GreB
E5E97_RS05695	ENOG4105E0F	Histidine kinase
E5E97_RS05705	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
E5E97_RS05710	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E5E97_RS05715	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E5E97_RS05720	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E5E97_RS05725	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E5E97_RS05730	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E5E97_RS05735	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
E5E97_RS05740	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E5E97_RS05745	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E5E97_RS05750	ENOG41083MP	50s ribosomal protein l29
E5E97_RS05755	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E5E97_RS05760	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E5E97_RS05765	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E5E97_RS05770	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E5E97_RS05775	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E5E97_RS05780	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E5E97_RS05785	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E5E97_RS05790	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E5E97_RS05795	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E5E97_RS05800	ENOG4105VPB	50S ribosomal protein L30
E5E97_RS05805	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E5E97_RS05810	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E5E97_RS05815	ENOG41067V7	50S ribosomal protein L36
E5E97_RS05820	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E5E97_RS05825	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E5E97_RS05830	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E5E97_RS05835	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5E97_RS05840	ENOG4108ZT0	50S ribosomal protein l17
E5E97_RS05885	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E5E97_RS05890	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
E5E97_RS05895	ENOG4108W5M	transcriptional regulator
E5E97_RS05900	ENOG4105EMU	Dehydrogenase
E5E97_RS05915	ENOG4105CUG	Oligopeptidase b
E5E97_RS05935	ENOG4107FS9	Membrane
E5E97_RS05950	ENOG4105JQN	Transcriptional regulator
E5E97_RS05965	ENOG4105VVZ	metal-binding protein
E5E97_RS05970	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
E5E97_RS05990	ENOG4105E4C	Lytic transglycosylase catalytic
E5E97_RS06000	ENOG4107RZC	phospholipase d
E5E97_RS06010	ENOG4105EJ2	Transcriptional regulator
E5E97_RS06015	ENOG4108Y73	Membrane
E5E97_RS06025	ENOG4106H78	methyltransferase
E5E97_RS06030	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E5E97_RS06035	ENOG4105CAK	Cell division ATP-binding protein ftsE
E5E97_RS06040	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
E5E97_RS06050	ENOG41077A9	carbonic anhydrase
E5E97_RS06055	ENOG4105CZE	histidine utilization repressor
E5E97_RS06060	ENOG4105CI2	imidazolone-5-propionate hydrolase
E5E97_RS06065	ENOG41088SP	formiminoglutamate hydrolase
E5E97_RS06070	ENOG4105CGP	Urocanate hydratase
E5E97_RS06075	ENOG4105C84	Histidine ammonia-lyase
E5E97_RS06080	ENOG4105EWV	Sodium calcium exchanger membrane region
E5E97_RS06085	ENOG4107XTP	(EAL) domain protein
E5E97_RS06090	ENOG41062P1	Diguanylate cyclase phosphodiesterase
E5E97_RS06120	ENOG4105GVR	general secretion pathway protein D
E5E97_RS06135	ENOG4107QHF	type ii secretion system protein e
E5E97_RS06140	ENOG4105D7Q	type ii secretion system
E5E97_RS06155	ENOG4105KHS	type IV fimbrial pilin protein
E5E97_RS06160	ENOG4106855	Competence protein
E5E97_RS06190	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
E5E97_RS06195	ENOG4105VQ7	Rod shape-determining protein MreD
E5E97_RS06200	ENOG4108Z03	MAF-like protein
E5E97_RS06205	ENOG4105C03	ribonuclease
E5E97_RS06210	ENOG4105QD6	exported protein
E5E97_RS06230	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
E5E97_RS06235	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
E5E97_RS06250	ENOG4105C5Y	PTS System
E5E97_RS06255	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
E5E97_RS06270	ENOG4105CSH	Transporter
E5E97_RS06280	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E97_RS06285	ENOG4105BZU	Histidine kinase
E5E97_RS06290	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
E5E97_RS06295	ENOG4107MMM	Anti-sigma-factor antagonist
E5E97_RS06300	ENOG4107SDU	Methyl-accepting chemotaxis
E5E97_RS06315	ENOG4105F0S	class B acid phosphatase
E5E97_RS06320	ENOG4105CGZ	zinc metallopeptidase
E5E97_RS06330	ENOG4108HU6	Metal dependent phosphohydrolase
E5E97_RS06345	ENOG4105EEQ	Na H antiporter
E5E97_RS06350	ENOG4105C3R	Methionine synthase
E5E97_RS06355	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E5E97_RS06360	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E5E97_RS06370	ENOG4105ETX	regulatoR
E5E97_RS06385	ENOG4108MR7	Arylsulfotransferase
E5E97_RS06390	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
E5E97_RS06395	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E5E97_RS06400	ENOG4105D06	uba thif-type nad fad binding protein
E5E97_RS06410	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E5E97_RS06415	ENOG4105D41	biosynthesis protein thiH
E5E97_RS06430	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
E5E97_RS06450	ENOG4105BZU	Histidine kinase
E5E97_RS06455	ENOG4105C44	Serine transporter
E5E97_RS06460	ENOG4108TPP	exopolysaccharide synthesis
E5E97_RS06475	ENOG4105N0V	mono-oxygenase ydhR
E5E97_RS06480	ENOG4105KVH	Transcriptional regulator
E5E97_RS06505	ENOG4105E0K	tonB-dependent siderophore receptor
E5E97_RS06520	ENOG4105CBT	Fructose-1,6-bisphosphatase
E5E97_RS06535	ENOG4105ECF	c-methyltransferase
E5E97_RS06540	ENOG41076E6	Uroporphyrinogen-III Synthase
E5E97_RS06545	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E5E97_RS06550	ENOG4107T0K	Adenylate cyclase
E5E97_RS06555	ENOG4106CJB	Phospholipase Carboxylesterase
E5E97_RS06560	ENOG4105XQ6	frataxin-like protein
E5E97_RS06570	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E5E97_RS06575	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E5E97_RS06585	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5E97_RS06590	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
E5E97_RS06610	ENOG4108Z86	Glutamine amidotransferase
E5E97_RS06615	ENOG410667J	hydrolase
E5E97_RS06630	ENOG4105CJ1	ABC, transporter
E5E97_RS06640	ENOG4108I62	cina-like protein
E5E97_RS06645	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
E5E97_RS06650	ENOG4105CVG	Homoserine O-transsuccinylase
E5E97_RS06660	ENOG4108YXU	transcriptional regulator AsnC family
E5E97_RS06665	ENOG4105E0M	Sulfatase
E5E97_RS06685	ENOG4105KT7	mgtC SapB transporter
E5E97_RS06705	ENOG4105EMU	Dehydrogenase
E5E97_RS06710	ENOG4105DZW	Dipeptidase
E5E97_RS06735	ENOG4108IQK	o-acetylhomoserine
E5E97_RS06765	ENOG4107IFA	Lipase (EC 3.1.1.3)
E5E97_RS06775	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E5E97_RS06780	ENOG4108UB4	uncharacterized protein ygjQ
E5E97_RS06785	ENOG4107MM9	BNR Asp-box repeat-containing protein
E5E97_RS06795	ENOG4105HMV	Fimbrial protein
E5E97_RS06805	ENOG4106PG1	outer membrane usher protein
E5E97_RS06810	ENOG4108FZ9	Chaperone
E5E97_RS06815	ENOG4108MDY	Fimbrial
E5E97_RS06830	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E97_RS06835	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
E5E97_RS06840	ENOG4108IPT	Naphthoate synthase
E5E97_RS06845	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
E5E97_RS06850	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
E5E97_RS06855	ENOG4105E4F	Isochorismate synthase
E5E97_RS06860	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
E5E97_RS06885	ENOG4105C1J	atp-dependent rna helicase
E5E97_RS06890	ENOG4105D9N	nucleoside
E5E97_RS06895	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
E5E97_RS06900	ENOG4108UPT	UPF0178 protein
E5E97_RS06925	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E5E97_RS06930	ENOG4105E61	Mannitol repressor protein
E5E97_RS06935	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
E5E97_RS06940	ENOG4105CTS	PTS system mannitol-specific
E5E97_RS06955	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
E5E97_RS06965	ENOG4105NNS	Autoinducer synthesis protein
E5E97_RS06970	ENOG4105VJY	transcriptional regulator
E5E97_RS06975	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
E5E97_RS06980	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
E5E97_RS06985	ENOG4108XTF	Outer Membrane Lipoprotein
E5E97_RS06995	ENOG4105VXR	cytoplasmic protein
E5E97_RS07010	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
E5E97_RS07015	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
E5E97_RS07020	ENOG4105VEJ	Heat shock protein
E5E97_RS07030	ENOG4105GVR	general secretion pathway protein D
E5E97_RS07035	ENOG4107QHF	type ii secretion system protein e
E5E97_RS07040	ENOG4105D7Q	type ii secretion system
E5E97_RS07045	ENOG4108VAU	general secretion pathway protein G
E5E97_RS07095	ENOG4108UDW	Transcriptional regulator, luxr family
E5E97_RS07100	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E5E97_RS07105	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
E5E97_RS07110	ENOG4107RK2	ADP-ribose diphosphatase NudE
E5E97_RS07115	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E5E97_RS07120	ENOG4105C44	Serine transporter
E5E97_RS07125	ENOG4108Z7R	Chaperone CsaA
E5E97_RS07135	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
E5E97_RS07140	ENOG4105C28	cystathionine
E5E97_RS07145	ENOG4105CFH	Aspartokinase
E5E97_RS07155	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
E5E97_RS07165	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E5E97_RS07170	ENOG4105CAS	nag kinase
E5E97_RS07180	ENOG4105CDH	Citrulline--aspartate ligase
E5E97_RS07185	ENOG4105CH7	arginosuccinase
E5E97_RS07210	ENOG4108UW5	maltose o-acetyltransferase
E5E97_RS07215	ENOG4107PU6	Membrane
E5E97_RS07220	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E5E97_RS07230	ENOG4108I5D	sulfate abc transporter
E5E97_RS07235	ENOG4105ECW	sulfate abc transporter
E5E97_RS07240	ENOG4108IJ6	ABC transporter
E5E97_RS07245	ENOG4107R11	Transcriptional regulator
E5E97_RS07250	ENOG4108M1A	Chitin-binding protein
E5E97_RS07285	ENOG4107RE3	peptidase, S41
E5E97_RS07305	ENOG4105G0K	glycine radical enzyme YjjI family
E5E97_RS07310	ENOG41076CZ	activating enzyme
E5E97_RS07325	ENOG4105CGF	Aromatic amino acid aminotransferase
E5E97_RS07360	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
E5E97_RS07370	ENOG4105C1J	atp-dependent rna helicase
E5E97_RS07385	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
E5E97_RS07390	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E5E97_RS07405	ENOG4105XTV	UPF0231 protein
E5E97_RS07415	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
E5E97_RS07420	ENOG4107QQ0	gntp family
E5E97_RS07425	ENOG4105BZW	Glycerate kinase
E5E97_RS07440	ENOG4105HEI	LysR family (Transcriptional regulator
E5E97_RS07445	ENOG4105D9N	nucleoside
E5E97_RS07450	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E5E97_RS07455	ENOG4108YZN	class I peptide chain release factor
E5E97_RS07460	ENOG4108YZA	Nitrogen regulatory protein pii
E5E97_RS07475	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E5E97_RS07480	ENOG4105EZR	dyp-type peroxidase family protein
E5E97_RS07485	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
E5E97_RS07490	ENOG4105E5Z	arginine transporter ATP-binding subunit
E5E97_RS07495	ENOG4106PMH	Extracellular solute-binding protein family 3
E5E97_RS07500	ENOG4105GBT	ABC transporter
E5E97_RS07505	ENOG4105DMR	ABC, transporter
E5E97_RS07510	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
E5E97_RS07515	ENOG4108UV7	flagellar protein motX
E5E97_RS07520	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E5E97_RS07530	ENOG4108JU6	CBS domain protein
E5E97_RS07535	ENOG4106KVJ	cytochrome C assembly protein
E5E97_RS07540	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E5E97_RS07545	ENOG4105K5M	30s ribosomal protein S16
E5E97_RS07550	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E5E97_RS07555	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
E5E97_RS07560	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E5E97_RS07570	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
E5E97_RS07575	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E5E97_RS07580	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
E5E97_RS07585	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E5E97_RS07590	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
E5E97_RS07595	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E5E97_RS07745	ENOG4105ED4	portal protein
E5E97_RS07845	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5E97_RS07850	ENOG41063Z6	transcriptional regulator, lysR family
E5E97_RS07855	ENOG41080HT	Transcriptional regulator, arsr family
E5E97_RS07860	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
E5E97_RS07865	ENOG4105CJR	Integral membrane protein (MviN
E5E97_RS07875	ENOG4105DTN	riboflavin biosynthesis protein ribF
E5E97_RS07880	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E5E97_RS07885	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E5E97_RS07890	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E5E97_RS07895	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
E5E97_RS07955	ENOG4105C4K	Nad synthetase
E5E97_RS07960	ENOG4108YZA	Nitrogen regulatory protein pii
E5E97_RS07970	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
E5E97_RS07975	ENOG4106TD9	Diguanylate cyclase
E5E97_RS07980	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E5E97_RS08015	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
E5E97_RS08020	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
E5E97_RS08025	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E5E97_RS08030	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
E5E97_RS08035	ENOG4105DP0	ferredoxin-NADP reductase
E5E97_RS08060	ENOG4105W39	Membrane
E5E97_RS08070	ENOG4105D9M	gamma-glutamylcysteine synthetase
E5E97_RS08080	ENOG4108IQE	Amp-dependent synthetase and ligase
E5E97_RS08090	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
E5E97_RS08100	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
E5E97_RS08110	ENOG4105BZU	Histidine kinase
E5E97_RS08140	ENOG4108MJ3	acetyltransferase
E5E97_RS08145	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5E97_RS08155	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
E5E97_RS08165	ENOG4105DWY	Agmatine deiminase
E5E97_RS08170	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E5E97_RS08180	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
E5E97_RS08190	ENOG4105C1J	atp-dependent rna helicase
E5E97_RS08215	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
E5E97_RS08245	ENOG4105EA8	2-Nitropropane dioxygenase
E5E97_RS08280	ENOG4105E09	nadh pyrophosphatase
E5E97_RS08285	ENOG410804D	Sensor Signal Transduction Histidine Kinase
E5E97_RS08290	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E5E97_RS08295	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E5E97_RS08300	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5E97_RS08305	ENOG4105CT1	(ABC) transporter
E5E97_RS08310	ENOG4105CDA	abc transporter atp-binding protein
E5E97_RS08315	ENOG4105E5Q	amino acid AbC transporter
E5E97_RS08320	ENOG4105E5Q	amino acid AbC transporter
E5E97_RS08325	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
E5E97_RS08345	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E5E97_RS08350	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E5E97_RS08360	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS08365	ENOG4105EYW	Ion transport protein
E5E97_RS08370	ENOG4106MWK	domain protein
E5E97_RS08375	ENOG4105C26	Dehydrogenase
E5E97_RS08380	ENOG4105E09	nadh pyrophosphatase
E5E97_RS08385	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
E5E97_RS08390	ENOG4105DKQ	ROK family
E5E97_RS08395	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E5E97_RS08400	ENOG4105BZA	Phosphoglycerate kinase
E5E97_RS08405	ENOG4105D2N	Aldolase
E5E97_RS08410	ENOG4105CJP	fad dependent oxidoreductase
E5E97_RS08420	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E5E97_RS08450	ENOG4105Y75	tpr repeat protein
E5E97_RS08460	ENOG4108IYU	L-aspartate oxidase
E5E97_RS08465	ENOG4105EMN	RNA polymerase sigma factor
E5E97_RS08470	ENOG41069PW	sigma-e factor negative regulatory protein
E5E97_RS08485	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E5E97_RS08490	ENOG4105C3F	Signal peptidase i
E5E97_RS08505	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
E5E97_RS08510	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E5E97_RS08520	ENOG4105D2N	Aldolase
E5E97_RS08525	ENOG4105CE4	GlcNAc 6-P deacetylase
E5E97_RS08530	ENOG4108YTN	IIa component
E5E97_RS08535	ENOG4105F3R	pts system mannose fructose sorbose family iid
E5E97_RS08545	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
E5E97_RS08550	ENOG4105E70	isomerase
E5E97_RS08555	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
E5E97_RS08560	ENOG4105E98	transcriptional regulator DeoR family
E5E97_RS08570	ENOG4108W15	Protein of unknown function (DUF1456)
E5E97_RS08575	ENOG4105BZU	Histidine kinase
E5E97_RS08580	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E5E97_RS08585	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E5E97_RS08590	ENOG4105DXN	mazG family
E5E97_RS08595	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E5E97_RS08600	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E5E97_RS08605	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E5E97_RS08610	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
E5E97_RS08615	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
E5E97_RS08620	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
E5E97_RS08625	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E5E97_RS08630	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E5E97_RS08635	ENOG4108UM1	dedA family
E5E97_RS08640	ENOG4108K5P	(LipO)protein
E5E97_RS08650	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E5E97_RS08655	ENOG4105VCC	30S ribosomal protein S21
E5E97_RS08660	ENOG4105KTH	gatB Yqey
E5E97_RS08665	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E5E97_RS08670	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5E97_RS08695	ENOG4105C12	Phosphoribosylglycinamide synthetase
E5E97_RS08700	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E5E97_RS08710	ENOG4105NAE	bifunctional deaminase-reductase domain protein
E5E97_RS08720	ENOG4105CSA	Coproporphyrinogen iii oxidase
E5E97_RS08725	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E5E97_RS08735	ENOG4105D9R	oxidoreductase
E5E97_RS08745	ENOG4105D9U	N-acetyltransferase
E5E97_RS08750	ENOG4108Z9I	-acetyltransferase
E5E97_RS08765	ENOG4105EV4	Multidrug resistance protein mdtH
E5E97_RS08775	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
E5E97_RS08780	ENOG4108IJ0	Aspartate ammonia-lyase
E5E97_RS08785	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
E5E97_RS08795	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E5E97_RS08800	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E5E97_RS08810	ENOG4105BZU	Histidine kinase
E5E97_RS08820	ENOG4105D3G	Pseudouridine synthase
E5E97_RS08825	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
E5E97_RS08855	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E5E97_RS08865	ENOG4108IAB	Phoh family
E5E97_RS08870	ENOG4107T0D	ABC, transporter
E5E97_RS08875	ENOG4106SMU	thiamine transporter membrane protein
E5E97_RS08895	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E5E97_RS08900	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E5E97_RS08910	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E5E97_RS08920	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
E5E97_RS08935	ENOG4105C7K	acetolactate synthase
E5E97_RS08940	ENOG4108ZP8	Acetolactate synthase small subunit
E5E97_RS08945	ENOG4105C6K	Malic enzyme
E5E97_RS08950	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E5E97_RS08960	ENOG4105XWI	UPF0304 protein
E5E97_RS08965	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5E97_RS08970	ENOG4105RH4	Glycine cleavage system transcriptional repressor
E5E97_RS08975	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E5E97_RS08980	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E5E97_RS08985	ENOG4107QWK	SAICAR synthetase
E5E97_RS08995	ENOG4105EXG	Transcriptional regulator
E5E97_RS09000	ENOG4106173	Uncharacterized protein conserved in bacteria (DUF2057)
E5E97_RS09020	ENOG4105BZU	Histidine kinase
E5E97_RS09040	ENOG4105BZU	Histidine kinase
E5E97_RS09045	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS09050	ENOG4105MDZ	Transcriptional activator rfaH
E5E97_RS09055	ENOG4105D01	(LipO)protein
E5E97_RS09060	ENOG4108UMI	ABC transporter, permease
E5E97_RS09065	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E5E97_RS09080	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E5E97_RS09085	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E5E97_RS09090	ENOG4105K8N	protein family UPF0079, ATPase
E5E97_RS09095	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E5E97_RS09100	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E5E97_RS09105	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
E5E97_RS09110	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E5E97_RS09115	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E5E97_RS09120	ENOG4107QJR	hflk protein
E5E97_RS09125	ENOG4105EPW	hflc protein
E5E97_RS09135	ENOG4105EAH	synthase
E5E97_RS09140	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E5E97_RS09145	ENOG4105K46	50S ribosomal protein l27
E5E97_RS09150	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E5E97_RS09155	ENOG4105DWD	nucleoside recognition domain protein
E5E97_RS09160	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E97_RS09175	ENOG4108ESY	Metal dependent phosphohydrolase
E5E97_RS09180	ENOG4105DEN	Luciferase family
E5E97_RS09190	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E5E97_RS09200	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E5E97_RS09205	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E5E97_RS09215	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
E5E97_RS09220	ENOG4105EHM	Aminoglycoside phosphotransferase
E5E97_RS09225	ENOG4108S0S	Nucleotidyl transferase
E5E97_RS09230	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
E5E97_RS09235	ENOG4105C7N	Xanthine uracil vitamin C permease
E5E97_RS09245	ENOG4105C5H	ABC transporter
E5E97_RS09260	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
E5E97_RS09265	ENOG4105E4C	Lytic transglycosylase catalytic
E5E97_RS09285	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
E5E97_RS09290	ENOG4105D9N	nucleoside
E5E97_RS09320	ENOG4105EHG	Permease protein
E5E97_RS09330	ENOG41090JE	Utilization Protein
E5E97_RS09335	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
E5E97_RS09355	ENOG4105D05	Receptor
E5E97_RS09360	ENOG4105D8G	Major Facilitator superfamily
E5E97_RS09365	ENOG4105VMP	Transcriptional regulator
E5E97_RS09375	ENOG4105BZU	Histidine kinase
E5E97_RS09385	ENOG4108MA4	Peptidase M66
E5E97_RS09390	ENOG4108M1A	Chitin-binding protein
E5E97_RS09400	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
E5E97_RS09405	ENOG4108UKZ	OsmC family
E5E97_RS09420	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
E5E97_RS09425	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
E5E97_RS09430	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
E5E97_RS09435	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E5E97_RS09440	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E5E97_RS09445	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E5E97_RS09450	ENOG4105CKK	Glycosyl transferase, family 2
E5E97_RS09455	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E5E97_RS09460	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E5E97_RS09465	ENOG4105YP7	UPF0270 protein
E5E97_RS09475	ENOG4105DNZ	Alpha Beta Hydrolase
E5E97_RS09490	ENOG4105VKU	nucleicacid-binding protein
E5E97_RS09495	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E5E97_RS09510	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E5E97_RS09515	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5E97_RS09535	ENOG4105CGH	5'-nucleotidase
E5E97_RS09540	ENOG4105BZU	Histidine kinase
E5E97_RS09550	ENOG4105CDU	Replicative dna helicase
E5E97_RS09555	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E5E97_RS09565	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E5E97_RS09570	ENOG4105CFP	Peptidase U32
E5E97_RS09575	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
E5E97_RS09600	ENOG4105C9B	Cysteine desulfurase
E5E97_RS09605	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E5E97_RS09610	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
E5E97_RS09615	ENOG4105BZU	Histidine kinase
E5E97_RS09620	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS09625	ENOG4108V3W	Chemotaxis protein, CheW
E5E97_RS09635	ENOG4105CBS	Chea signal transduction histidine kinase
E5E97_RS09645	ENOG4108VYJ	response regulator receiver protein
E5E97_RS09650	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS09655	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E5E97_RS09670	ENOG4105CFP	Peptidase U32
E5E97_RS09695	ENOG4105CTD	carboxy-peptidase
E5E97_RS09720	ENOG4105E1F	short-chain dehydrogenase reductase
E5E97_RS09725	ENOG4105J5J	Outer membrane porin
E5E97_RS09730	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS09740	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
E5E97_RS09745	ENOG4105C0A	alcohol dehydrogenase
E5E97_RS09750	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
E5E97_RS09755	ENOG4105DET	Rhamnulokinase
E5E97_RS09760	ENOG4105DKG	l-rhamnose isomerase
E5E97_RS09765	ENOG4107YRA	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity)
E5E97_RS09770	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
E5E97_RS09800	ENOG4105KT5	UmuD protein
E5E97_RS09810	ENOG4105D70	Integrase catalytic subunit
E5E97_RS09815	ENOG4105F5W	AtP-binding protein
E5E97_RS09870	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E5E97_RS09880	ENOG4105E0X	reductase
E5E97_RS09890	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E5E97_RS09895	ENOG4105BZU	Histidine kinase
E5E97_RS09920	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E5E97_RS09925	ENOG4107RFB	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E5E97_RS09930	ENOG4105E0X	reductase
E5E97_RS09950	ENOG410600T	transposase
E5E97_RS09985	ENOG4105CQC	Prephenate dehydratase
E5E97_RS10015	ENOG4107SEY	Conserved Protein
E5E97_RS10020	ENOG4108XDN	Transcriptional regulator
E5E97_RS10025	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E5E97_RS10035	ENOG4105EMU	Dehydrogenase
E5E97_RS10075	ENOG4108RMU	ferritin dps family protein
E5E97_RS10080	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
E5E97_RS10090	ENOG4105CMR	udp-glucose 4-epimerase
E5E97_RS10095	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E5E97_RS10105	ENOG4105VJY	transcriptional regulator
E5E97_RS10110	ENOG4108WC9	type VI secretion system effector, hcp1 family
E5E97_RS10120	ENOG4105CS6	Rhs element vgr protein
E5E97_RS10150	ENOG4105C7K	acetolactate synthase
E5E97_RS10155	ENOG4107S0N	DJ-1 family
E5E97_RS10160	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
E5E97_RS10165	ENOG4108VPT	UPF0234 protein
E5E97_RS10170	ENOG4105DRB	nucleoside-specific channel-forming protein
E5E97_RS10175	ENOG4105EYM	Major Facilitator superfamily
E5E97_RS10185	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E5E97_RS10195	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
E5E97_RS10200	ENOG4105M85	Bola protein
E5E97_RS10205	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E97_RS10210	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E97_RS10215	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E97_RS10220	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E97_RS10225	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E97_RS10230	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
E5E97_RS10235	ENOG4105CJ2	(LipO)protein
E5E97_RS10250	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E5E97_RS10255	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS10260	ENOG4105ETT	transcriptional Regulator, LysR family
E5E97_RS10270	ENOG4105M08	Membrane
E5E97_RS10275	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
E5E97_RS10285	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E5E97_RS10290	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
E5E97_RS10295	ENOG4105EWT	decarboxylase family
E5E97_RS10300	ENOG4105BZU	Histidine kinase
E5E97_RS10310	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
E5E97_RS10315	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
E5E97_RS10320	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
E5E97_RS10345	ENOG4105WP7	tRNA pseudouridine synthase C
E5E97_RS10350	ENOG4105DR9	pseudouridine synthase
E5E97_RS10355	ENOG4105QDK	Flavodoxin
E5E97_RS10360	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
E5E97_RS10365	ENOG4107W52	maltose operon periplasmic protein
E5E97_RS10370	ENOG4105CI1	PTS System
E5E97_RS10375	ENOG4108T8E	UPF0325 protein
E5E97_RS10380	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
E5E97_RS10385	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
E5E97_RS10390	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E5E97_RS10395	ENOG4105CE9	30S ribosomal protein S2
E5E97_RS10400	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
E5E97_RS10405	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E5E97_RS10410	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
E5E97_RS10420	ENOG4105KNE	Phosphatidate cytidylyltransferase
E5E97_RS10425	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
E5E97_RS10430	ENOG4105DZP	Membrane-associated zinc metalloprotease
E5E97_RS10440	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
E5E97_RS10445	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5E97_RS10450	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
E5E97_RS10455	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5E97_RS10460	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5E97_RS10465	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E5E97_RS10470	ENOG4105C0B	DNA polymerase III (alpha subunit)
E5E97_RS10475	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
E5E97_RS10480	ENOG4108M3R	transcriptional activator CadC
E5E97_RS10485	ENOG4105D5Q	Arginine ornithine antiporter
E5E97_RS10490	ENOG4105CXN	decarboxylase
E5E97_RS10495	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
E5E97_RS10505	ENOG4105EQ2	LysR family Transcriptional regulator
E5E97_RS10510	ENOG4105C44	Serine transporter
E5E97_RS10515	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
E5E97_RS10520	ENOG4105EXG	Transcriptional regulator
E5E97_RS10525	ENOG4105ENX	hydrolase
E5E97_RS10530	ENOG4105ENX	hydrolase
E5E97_RS10535	ENOG4105EQ2	LysR family Transcriptional regulator
E5E97_RS10540	ENOG4105DVH	amino acid
E5E97_RS10545	ENOG4105KNA	-acetyltransferase
E5E97_RS10550	ENOG4105C5H	ABC transporter
E5E97_RS10560	ENOG4105C9K	Endothelin-converting enzyme 1
E5E97_RS10570	ENOG4105BZU	Histidine kinase
E5E97_RS10605	ENOG4107T9C	Alpha amylase catalytic region
E5E97_RS10635	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
E5E97_RS10640	ENOG4105EAQ	(twin-arginine translocation) pathway signal
E5E97_RS10650	ENOG4105EN6	Membrane
E5E97_RS10655	ENOG4105EXN	Sulfate transport protein CysZ
E5E97_RS10660	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E5E97_RS10670	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E5E97_RS10680	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
E5E97_RS10685	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
E5E97_RS10715	ENOG4105J12	Multidrug resistance protein mdtN
E5E97_RS10730	ENOG4105D2K	citrate carrier protein
E5E97_RS10750	ENOG4108IPJ	Membrane
E5E97_RS10760	ENOG4105C26	Dehydrogenase
E5E97_RS10765	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
E5E97_RS10770	ENOG4105C1G	acyl-Coa dehydrogenase
E5E97_RS10775	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
E5E97_RS10780	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
E5E97_RS10785	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E5E97_RS10790	ENOG4105BZU	Histidine kinase
E5E97_RS10795	ENOG4105DJH	phosphate
E5E97_RS10800	ENOG4105ERG	peptidase m48, ste24p
E5E97_RS10815	ENOG4106N3A	copper homeostasis protein cutc
E5E97_RS10820	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E5E97_RS10825	ENOG4105CJ1	ABC, transporter
E5E97_RS10845	ENOG4105PTV	Nudix Hydrolase
E5E97_RS10870	ENOG4105BZG	amino acid carrier protein
E5E97_RS10875	ENOG4108KMH	lipoate-protein ligase a
E5E97_RS10880	ENOG4105C2W	permease
E5E97_RS10890	ENOG4105RKX	Protein of unknown function (DUF2498)
E5E97_RS10895	ENOG4105UQX	Mate efflux family protein
E5E97_RS10905	ENOG4107R1I	NAD-dependent malic enzyme
E5E97_RS10910	ENOG4105UYK	outer membrane protein a
E5E97_RS10915	ENOG4105UYK	outer membrane protein a
E5E97_RS10920	ENOG4105UYK	outer membrane protein a
E5E97_RS10935	ENOG4105C8J	)-transporter
E5E97_RS10940	ENOG4105D78	K07001 NTE family protein
E5E97_RS10945	ENOG4105BZU	Histidine kinase
E5E97_RS10950	ENOG4105J12	Multidrug resistance protein mdtN
E5E97_RS10955	ENOG4105BZS	acriflavin resistance protein
E5E97_RS10965	ENOG4105CCT	upf0313 protein
E5E97_RS10995	ENOG4105EP9	oxidoreductase
E5E97_RS11005	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
E5E97_RS11010	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
E5E97_RS11015	ENOG4105E4C	Lytic transglycosylase catalytic
E5E97_RS11040	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E5E97_RS11050	ENOG4105CIY	formyltetrahydrofolate deformylase
E5E97_RS11055	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E5E97_RS11065	ENOG4107QR8	Thioredoxin
E5E97_RS11070	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
E5E97_RS11075	ENOG4107TT5	NLP P60 protein
E5E97_RS11080	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
E5E97_RS11145	ENOG4105XB7	anti-repressor protein
E5E97_RS11165	ENOG4105DFP	Integrase
E5E97_RS11185	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
E5E97_RS11190	ENOG4105KNY	Microcompartments protein
E5E97_RS11195	ENOG4105F1A	Pyruvate formate-lyase
E5E97_RS11200	ENOG4105C6N	Formate acetyltransferase
E5E97_RS11205	ENOG4105C0A	alcohol dehydrogenase
E5E97_RS11215	ENOG4105C0A	alcohol dehydrogenase
E5E97_RS11220	ENOG4105KNY	Microcompartments protein
E5E97_RS11225	ENOG4105KNY	Microcompartments protein
E5E97_RS11230	ENOG4105KNY	Microcompartments protein
E5E97_RS11250	ENOG4105CBN	LysR family transcriptional regulator
E5E97_RS11255	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E5E97_RS11260	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
E5E97_RS11270	ENOG4107SSZ	Phosphatase
E5E97_RS11280	ENOG4107QPN	acyl-Coa dehydrogenase
E5E97_RS11285	ENOG4105BZS	acriflavin resistance protein
E5E97_RS11295	ENOG4105CA9	Pyruvate kinase
E5E97_RS11300	ENOG4106KNT	transcriptional regulator
E5E97_RS11315	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E5E97_RS11320	ENOG4108JJA	ABC, transporter
E5E97_RS11325	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
E5E97_RS11330	ENOG4108JJA	ABC, transporter
E5E97_RS11340	ENOG4108RC6	RTX toxin
E5E97_RS11345	ENOG4105EUK	rtx toxin RtxA
E5E97_RS11355	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
E5E97_RS11360	ENOG4105F2I	Transposase
E5E97_RS11365	ENOG4105BZU	Histidine kinase
E5E97_RS11475	ENOG4108C33	Resolvase
E5E97_RS11505	ENOG4105VUF	Transcriptional regulator
E5E97_RS11510	ENOG4108YX2	DNA-binding protein
E5E97_RS11555	ENOG4105DIJ	Phosphoethanolamine transferase
E5E97_RS11560	ENOG4105DIJ	Phosphoethanolamine transferase
E5E97_RS11620	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E97_RS11635	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
E5E97_RS11640	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
E5E97_RS11645	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E5E97_RS11655	ENOG4108JIR	Flagellum-specific ATP synthase
E5E97_RS11675	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E5E97_RS11680	ENOG4105DD5	Flagellar motor switch protein
E5E97_RS11685	ENOG4105VTB	flagellar biosynthesis protein fliO
E5E97_RS11690	ENOG4105CN7	Flagellar biosynthetic protein FliP
E5E97_RS11695	ENOG4105VS8	Flagellar biosynthetic protein fliq
E5E97_RS11700	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E5E97_RS11705	ENOG4105D00	flagellar biosynthetic protein flhB
E5E97_RS11710	ENOG4105D7B	Flagellar biosynthesis protein flha
E5E97_RS11715	ENOG4105FZW	flagellar biosynthesis regulator FlhF
E5E97_RS11725	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5E97_RS11730	ENOG4108VYJ	response regulator receiver protein
E5E97_RS11735	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
E5E97_RS11745	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E5E97_RS11750	ENOG4105E14	MotA TolQ exbB proton channel
E5E97_RS11755	ENOG4108SEK	ompa motb domain protein
E5E97_RS11760	ENOG4107QJE	Chromosome Partitioning Protein
E5E97_RS11770	ENOG4108V3W	Chemotaxis protein, CheW
E5E97_RS11785	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
E5E97_RS11790	ENOG41060IM	Heme exporter protein
E5E97_RS11795	ENOG4105X3C	heme exporter protein
E5E97_RS11800	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
E5E97_RS11805	ENOG4105DA4	cytochrome c-type biogenesis protein
E5E97_RS11810	ENOG4107QX9	Thiol disulfide interChange protein
E5E97_RS11815	ENOG4105KWW	Biogenesis protein
E5E97_RS11820	ENOG4105KWW	Biogenesis protein
E5E97_RS11825	ENOG410903C	(LipO)protein
E5E97_RS11830	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E5E97_RS11835	ENOG4105M2J	Glutaredoxin
E5E97_RS11855	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
E5E97_RS11870	ENOG4108YYD	acetyltransferase
E5E97_RS11880	ENOG4105EZE	Cupin 4 family protein
E5E97_RS11885	ENOG4107QTF	adenylosuccinate lyase
E5E97_RS11890	ENOG41075W9	High frequency lysogenization protein HflD homolog
E5E97_RS11895	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E5E97_RS11905	ENOG4108R99	pseudouridine synthase
E5E97_RS11915	ENOG4108YRF	PTS System
E5E97_RS11920	ENOG4105CXY	transporter
E5E97_RS11925	ENOG4105DM4	PTS System
E5E97_RS11935	ENOG4108W0I	acetyltransferase
E5E97_RS11945	ENOG4108Z6Z	Transcriptional regulator
E5E97_RS11955	ENOG4107P2S	Transcriptional regulator
E5E97_RS11960	ENOG4105CI1	PTS System
E5E97_RS11965	ENOG4105C87	Aminotransferase class I and II
E5E97_RS11980	ENOG4105DM4	PTS System
E5E97_RS11995	ENOG4105EIP	mannose-6-phosphate isomerase
E5E97_RS12000	ENOG4106R3P	AraC family transcriptional regulator
E5E97_RS12005	ENOG4108HMX	isocitrate dehydrogenase (NADP)
E5E97_RS12020	ENOG4105BZC	d-serine deaminase
E5E97_RS12025	ENOG4105W8I	Transcriptional regulator
E5E97_RS12030	ENOG4108NZE	NAGC-like transcriptional regulator
E5E97_RS12075	ENOG410890F	Dynamin family
E5E97_RS12115	ENOG4106F1P	AAA ATPase, central domain protein
E5E97_RS12175	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E5E97_RS12195	ENOG4105W5Q	DNA repair protein (RadC
E5E97_RS12220	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E5E97_RS12225	ENOG4108Z1B	Cyclase dehydrase
E5E97_RS12230	ENOG4105VDB	UPF0125 protein
E5E97_RS12235	ENOG4105K4T	epimerase
E5E97_RS12240	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E5E97_RS12245	ENOG4105C0A	alcohol dehydrogenase
E5E97_RS12250	ENOG4107SXA	Phosphorylase
E5E97_RS12255	ENOG4105D3G	Pseudouridine synthase
E5E97_RS12260	ENOG4105DU0	nucleoside hydrolase
E5E97_RS12275	ENOG4105RX8	Protein of unknown function (DUF1523)
E5E97_RS12280	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS12285	ENOG410829K	Lysine exporter protein (Lyse ygga)
E5E97_RS12295	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E5E97_RS12320	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E5E97_RS12325	ENOG4105KUZ	arsenate reductase
E5E97_RS12330	ENOG4107TII	Recombinase
E5E97_RS12365	ENOG4105CEE	C4-dicarboxylate transporter
E5E97_RS12380	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
E5E97_RS12385	ENOG4105C5S	asparaginyl-tRNA synthetase
E5E97_RS12405	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
E5E97_RS12410	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E5E97_RS12415	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E5E97_RS12420	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
E5E97_RS12425	ENOG4105D0M	Protease HtpX homolog
E5E97_RS12430	ENOG4107SDU	Methyl-accepting chemotaxis
E5E97_RS12435	ENOG4105QVC	MOSC domain-containing protein
E5E97_RS12435	ENOG4105QVC	MOSC domain-containing protein
E5E97_RS12445	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
E5E97_RS12465	ENOG4105UQX	Mate efflux family protein
E5E97_RS12485	ENOG4105C6T	cysteine synthase
E5E97_RS12505	ENOG4107Z3H	Transcriptional regulator, TetR family
E5E97_RS12510	ENOG4107RGH	Aldehyde dehydrogenase
E5E97_RS12520	ENOG4107TT5	NLP P60 protein
E5E97_RS12530	ENOG4105C5Q	Transcriptional regulator
E5E97_RS12535	ENOG4105D3R	alkyl hydroperoxide reductase
E5E97_RS12555	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
E5E97_RS12560	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
E5E97_RS12565	ENOG41081XQ	Conserved Protein
E5E97_RS12570	ENOG4105C9M	aspartyl-trna synthetase
E5E97_RS12575	ENOG4105CDY	transcriptional regulatory protein
E5E97_RS12580	ENOG4105DIJ	Phosphoethanolamine transferase
E5E97_RS12585	ENOG4105E2R	ROK family
E5E97_RS12590	ENOG4105CE4	GlcNAc 6-P deacetylase
E5E97_RS12595	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
E5E97_RS12600	ENOG4105CI1	PTS System
E5E97_RS12605	ENOG4105E2D	ec 3.2.1.52
E5E97_RS12610	ENOG4105CX6	glutaminyL-tRNA synthetase
E5E97_RS12615	ENOG41090R7	Ferric uptake
E5E97_RS12625	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
E5E97_RS12630	ENOG4105NNH	LexA regulated protein
E5E97_RS12640	ENOG4105EV9	Alpha Beta Hydrolase
E5E97_RS12645	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
E5E97_RS12650	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
E5E97_RS12675	ENOG4105CVE	Lytic murein transglycosylase
E5E97_RS12680	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
E5E97_RS12685	ENOG4108VGW	abc transporter atp-binding protein
E5E97_RS12695	ENOG4105VNH	ABC transporter solute-binding protein
E5E97_RS12705	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
E5E97_RS12720	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E5E97_RS12730	ENOG4105CFU	surface antigen
E5E97_RS12755	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
E5E97_RS12760	ENOG4105BZU	Histidine kinase
E5E97_RS12765	ENOG4107SC1	transglycosylase
E5E97_RS12770	ENOG41060NJ	transcriptional regulator
E5E97_RS12780	ENOG4105NAU	thioesterase Superfamily protein
E5E97_RS12795	ENOG4105E9H	Lytic Murein transglycosylase
E5E97_RS12800	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E5E97_RS12805	ENOG4105D1A	Methyltransferase
E5E97_RS12810	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E5E97_RS12815	ENOG4107RZZ	dna polymerase iii epsilon subunit
E5E97_RS12825	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E97_RS12830	ENOG4107QPN	acyl-Coa dehydrogenase
E5E97_RS12835	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E5E97_RS12840	ENOG4105E7A	Glutamine amidotransferase
E5E97_RS12850	ENOG4105CHW	UPF0052 protein
E5E97_RS12860	ENOG4105BZU	Histidine kinase
E5E97_RS12870	ENOG4105WH1	Two component transcriptional regulator luxr family
E5E97_RS12875	ENOG4105BZU	Histidine kinase
E5E97_RS12880	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E5E97_RS12885	ENOG4108ZNS	ferredoxin-type protein NapF
E5E97_RS12895	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
E5E97_RS12900	ENOG4108BGM	Quinol dehydrogenase periplasmic component
E5E97_RS12905	ENOG4105GXZ	Ferredoxin-type protein NapH
E5E97_RS12915	ENOG4105CUW	cytochrome C-TYPE protein
E5E97_RS12920	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E5E97_RS12925	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E5E97_RS12930	ENOG4105M00	molybdopterin converting factor, subunit 1
E5E97_RS12935	ENOG4108ZAF	Molybdopterin
E5E97_RS12940	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E5E97_RS12945	ENOG4105E0C	molybdate abc transporter
E5E97_RS12950	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E5E97_RS12955	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E5E97_RS12960	ENOG4105D06	uba thif-type nad fad binding protein
E5E97_RS12965	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E5E97_RS12970	ENOG4105EUJ	GTP cyclohydrolase i
E5E97_RS12975	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS12980	ENOG4105CKU	formyltetrahydrofolate synthetase
E5E97_RS12990	ENOG4105CC0	LysR family Transcriptional regulator
E5E97_RS12995	ENOG4108YYC	ycei family
E5E97_RS13020	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
E5E97_RS13030	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
E5E97_RS13045	ENOG4108NVR	Methyl-accepting chemotaxis
E5E97_RS13055	ENOG4105KME	endoribonuclease L-psp
E5E97_RS13060	ENOG4105CEM	UPF0597 protein
E5E97_RS13075	ENOG4108R4U	Hnh endonuclease
E5E97_RS13085	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
E5E97_RS13095	ENOG4105D82	Glutamate dehydrogenase
E5E97_RS13100	ENOG4105FE9	pseudouridine synthase
E5E97_RS13110	ENOG4105DJ2	Major Facilitator Superfamily
E5E97_RS13125	ENOG4105D2S	major facilitator superfamily
E5E97_RS13135	ENOG4106428	Protein of unknown function (DUF2496)
E5E97_RS13150	ENOG4108Q2J	Inner membrane protein YebE
E5E97_RS13165	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E5E97_RS13170	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E5E97_RS13180	ENOG4105F27	Major Facilitator
E5E97_RS13185	ENOG4105CV8	reductase
E5E97_RS13205	ENOG4105HEI	LysR family (Transcriptional regulator
E5E97_RS13210	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
E5E97_RS13215	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
E5E97_RS13220	ENOG4105CXY	transporter
E5E97_RS13225	ENOG4105E98	transcriptional regulator DeoR family
E5E97_RS13230	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
E5E97_RS13235	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
E5E97_RS13240	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5E97_RS13250	ENOG4105CVI	Transcriptional regulator
E5E97_RS13255	ENOG4108WFC	UPF0438 protein yifE
E5E97_RS13260	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
E5E97_RS13280	ENOG4105CUG	Oligopeptidase b
E5E97_RS13285	ENOG4105D05	Receptor
E5E97_RS13290	ENOG4105E68	Sulfatase
E5E97_RS13295	ENOG4105PAN	UPF0352 protein
E5E97_RS13300	ENOG4106V8H	Nucleoid-associated protein
E5E97_RS13305	ENOG4107FKK	extracellular solute-binding protein family 1
E5E97_RS13310	ENOG4105D56	permease protein
E5E97_RS13320	ENOG4108IJ9	(ABC) transporter
E5E97_RS13325	ENOG4105CSR	polyphosphate kinase 2
E5E97_RS13345	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E5E97_RS13350	ENOG4105ERG	peptidase m48, ste24p
E5E97_RS13360	ENOG4105K89	arsenate reductase
E5E97_RS13375	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
E5E97_RS13380	ENOG4105DYB	Isoaspartyl dipeptidase
E5E97_RS13385	ENOG4105DWU	Membrane
E5E97_RS13390	ENOG4108JEH	abc transporter atp-binding protein
E5E97_RS13395	ENOG4106PMH	Extracellular solute-binding protein family 3
E5E97_RS13400	ENOG4105DSP	amino acid AbC transporter
E5E97_RS13410	ENOG41084CK	capsule polysaccharide
E5E97_RS13415	ENOG4105E12	capsule polysaccharide
E5E97_RS13425	ENOG4107VDP	teichoic acid biosynthesis
E5E97_RS13430	ENOG4107VDP	teichoic acid biosynthesis
E5E97_RS13440	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E5E97_RS13445	ENOG4107V1M	polysaccharide export protein
E5E97_RS13460	ENOG41090SZ	ABC-2 type transporter
E5E97_RS13475	ENOG4105F1A	Pyruvate formate-lyase
E5E97_RS13480	ENOG4105BZU	Histidine kinase
E5E97_RS13485	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
E5E97_RS13500	ENOG4105J12	Multidrug resistance protein mdtN
E5E97_RS13505	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E5E97_RS13515	ENOG4105CH2	amidohydrolase
E5E97_RS13520	ENOG4105DN3	alpha-2-macroglobulin domain protein
E5E97_RS13525	ENOG4108JQB	penicillin-binding protein 1C
E5E97_RS13535	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
E5E97_RS13545	ENOG4105EN6	Membrane
E5E97_RS13550	ENOG4105I03	Flagellin
E5E97_RS13555	ENOG4105I03	Flagellin
E5E97_RS13570	ENOG4105MQ3	flagellar protein FliS
E5E97_RS13595	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
E5E97_RS13615	ENOG4105ECY	inositol monophosphatase
E5E97_RS13625	ENOG4105CYM	Glutathione S-transferase
E5E97_RS13630	ENOG4105E5M	Multidrug resistance protein D
E5E97_RS13640	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
E5E97_RS13650	ENOG4105D0A	hydroxylase
E5E97_RS13655	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E5E97_RS13660	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E5E97_RS13665	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E5E97_RS13670	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E5E97_RS13700	ENOG4105D6J	arsenicaL-resistance protein
E5E97_RS13705	ENOG4105K89	arsenate reductase
E5E97_RS13730	ENOG4105D3R	alkyl hydroperoxide reductase
E5E97_RS13735	ENOG4105W87	Cbs domain
E5E97_RS13740	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E5E97_RS13745	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E5E97_RS13750	ENOG4105VIE	preprotein translocase, subunit YajC
E5E97_RS13755	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5E97_RS13760	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5E97_RS13765	ENOG4105KHC	sulfurtransferase
E5E97_RS13795	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
E5E97_RS13805	ENOG4105C3J	Cysteine desulfurase
E5E97_RS13810	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
E5E97_RS13815	ENOG4108Z4V	iron-sulfur cluster assembly
E5E97_RS13820	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
E5E97_RS13825	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
E5E97_RS13830	ENOG4108ZIT	Ferredoxin, 2FE-2S
E5E97_RS13840	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E5E97_RS13845	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E5E97_RS13850	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
E5E97_RS13860	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
E5E97_RS13865	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E5E97_RS13870	ENOG4105CUT	histidyl-tRNA synthetase
E5E97_RS13875	ENOG4105N21	Membrane
E5E97_RS13880	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E5E97_RS13885	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E5E97_RS13890	ENOG4105VPD	cellular component movement
E5E97_RS13895	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E5E97_RS13900	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
E5E97_RS13905	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E97_RS13910	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E97_RS13920	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5E97_RS13925	ENOG4105C8S	subunit m
E5E97_RS13930	ENOG4105D65	subunit l
E5E97_RS13935	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5E97_RS13940	ENOG4107UFS	subunit j
E5E97_RS13945	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5E97_RS13950	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
E5E97_RS13955	ENOG4108IEH	NADH dehydrogenase subunit g
E5E97_RS13960	ENOG4107QIZ	NADH dehydrogenase
E5E97_RS13965	ENOG4105GKE	subunit e
E5E97_RS13970	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5E97_RS13975	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5E97_RS13980	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E5E97_RS13985	ENOG4105ER2	Ompa motb domain protein
E5E97_RS13990	ENOG4105E14	MotA TolQ exbB proton channel
E5E97_RS14010	ENOG4105HA9	of methanol dehydrogenase type
E5E97_RS14020	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
E5E97_RS14030	ENOG4105VFU	Rna-binding protein
E5E97_RS14035	ENOG4107RGM	aldo keto reductase
E5E97_RS14060	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E97_RS14065	ENOG4105CBN	LysR family transcriptional regulator
E5E97_RS14075	ENOG4105BZU	Histidine kinase
E5E97_RS14080	ENOG4108DBC	nitroreductase
E5E97_RS14100	ENOG4105CMU	LysR family (Transcriptional regulator
E5E97_RS14105	ENOG4107R11	Transcriptional regulator
E5E97_RS14110	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
E5E97_RS14115	ENOG4105CAT	Cytidine monophosphate kinase
E5E97_RS14120	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E5E97_RS14125	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E5E97_RS14135	ENOG4105CFV	Tetratricopeptide repeat protein
E5E97_RS14140	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
E5E97_RS14155	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
E5E97_RS14160	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E5E97_RS14165	ENOG4105VRT	cytoplasmic protein
E5E97_RS14170	ENOG4108WBT	adenosyltransferase
E5E97_RS14180	ENOG4107S6Z	Na H antiporter
E5E97_RS14185	ENOG4107104	thymidine kinase
E5E97_RS14195	ENOG4108RMJ	sensory transduction regulator
E5E97_RS14205	ENOG4108WC9	type VI secretion system effector, hcp1 family
E5E97_RS14210	ENOG4105CS6	Rhs element vgr protein
E5E97_RS14315	ENOG4105CS6	Rhs element vgr protein
E5E97_RS14320	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
E5E97_RS14350	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
E5E97_RS14355	ENOG4105VEQ	Cold shock protein
E5E97_RS14360	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E5E97_RS14365	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5E97_RS14370	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E5E97_RS14375	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
E5E97_RS14380	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E5E97_RS14385	ENOG4107MBR	17 kDa surface antigen
E5E97_RS14390	ENOG4105BZU	Histidine kinase
E5E97_RS14395	ENOG4105C3M	thioredoxin reductase
E5E97_RS14400	ENOG4105DCF	alanine dehydrogenase
E5E97_RS14405	ENOG4105EW9	transcriptional regulator AsnC family
E5E97_RS14410	ENOG4105CNU	cell division protein FtsK
E5E97_RS14415	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
E5E97_RS14420	ENOG4105D1H	recombination factor protein RarA
E5E97_RS14425	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E5E97_RS14430	ENOG4105E96	Colicin v production protein
E5E97_RS14435	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E5E97_RS14440	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
E5E97_RS14445	ENOG4108JQ2	peptide transport system atp-binding protein
E5E97_RS14450	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
E5E97_RS14455	ENOG4108EU3	peptide transport system, permease
E5E97_RS14460	ENOG4108I5W	peptide transport system, permease protein
E5E97_RS14465	ENOG4108J59	Extracellular solute-binding protein, family 5
E5E97_RS14470	ENOG4105E51	psp operon transcriptional activator
E5E97_RS14475	ENOG41087YS	Phage shock protein A
E5E97_RS14480	ENOG4105YYT	phage shock protein B
E5E97_RS14490	ENOG4105CM6	amino acid regulated cytosolic protein
E5E97_RS14495	ENOG4106K28	UPF0283 membrane protein
E5E97_RS14500	ENOG4105MIR	Phenylalanine 4-monooxygenase
E5E97_RS14505	ENOG41090A4	Pterin carbinolamine dehydratase
E5E97_RS14520	ENOG4108WS1	
E5E97_RS14530	ENOG41090EK	ompa motb domain protein
E5E97_RS14535	ENOG4105EE5	Membrane protein terC
E5E97_RS14545	ENOG4105MH2	YfcL protein
E5E97_RS14550	ENOG4108IQE	Amp-dependent synthetase and ligase
E5E97_RS14555	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
E5E97_RS14560	ENOG41067MG	lrgb family
E5E97_RS14570	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
E5E97_RS14580	ENOG4105CJB	Exodeoxyribonuclease I
E5E97_RS14585	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
E5E97_RS14595	ENOG4105EF1	ribulokinase
E5E97_RS14600	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
E5E97_RS14610	ENOG4105CNN	ABC, transporter
E5E97_RS14620	ENOG4105HEI	LysR family (Transcriptional regulator
E5E97_RS14625	ENOG4105EUB	pirin domain protein
E5E97_RS14630	ENOG4105YK5	50S ribosomal protein L36
E5E97_RS14635	ENOG4105NRA	50s ribosomal protein l31 type b
E5E97_RS14650	ENOG4108VKG	metal-dependent hydrolase
E5E97_RS14665	ENOG4105CEE	C4-dicarboxylate transporter
E5E97_RS14675	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
E5E97_RS14680	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E5E97_RS14695	ENOG4105BZN	citrate synthase
E5E97_RS14700	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
E5E97_RS14705	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
E5E97_RS14710	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
E5E97_RS14715	ENOG4105E33	succinate dehydrogenase
E5E97_RS14720	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E5E97_RS14725	ENOG4105C7S	Dehydrogenase
E5E97_RS14730	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
E5E97_RS14735	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E5E97_RS14755	ENOG4105CJP	fad dependent oxidoreductase
E5E97_RS14770	ENOG4105C4Y	ABC transporter
E5E97_RS14780	ENOG4107STF	Involved in phosphonate degradation (By similarity)
E5E97_RS14790	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
E5E97_RS14795	ENOG4105C6N	Formate acetyltransferase
E5E97_RS14800	ENOG4105TMB	Formate nitrite transporter
E5E97_RS14805	ENOG4105DDY	UPF0142 protein ycaO
E5E97_RS14815	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E5E97_RS14835	ENOG4108RYK	Nad-dependent epimerase dehydratase
E5E97_RS14840	ENOG4105CR8	Transcriptional regulator
E5E97_RS14850	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
E5E97_RS14855	ENOG4105E0K	tonB-dependent siderophore receptor
E5E97_RS14865	ENOG4105DZ2	Transcriptional regulator
E5E97_RS14870	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E5E97_RS14895	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E5E97_RS14900	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
E5E97_RS14910	ENOG4105C0F	tryptophanase EC 4.1.99.1
E5E97_RS14915	ENOG41061WM	D-Alanyl-D-Alanine
E5E97_RS14920	ENOG4108Z4K	mutator MutT protein
E5E97_RS14925	ENOG4108DMF	Cytochrome C biogenesis protein
E5E97_RS14930	ENOG4107QX9	Thiol disulfide interChange protein
E5E97_RS14935	ENOG4105DA4	cytochrome c-type biogenesis protein
E5E97_RS14940	ENOG4105DVI	reductase, NrfD
E5E97_RS14945	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E5E97_RS14950	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
E5E97_RS14970	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E5E97_RS14975	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
E5E97_RS14980	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
E5E97_RS14985	ENOG4105K5B	UPF0225 protein
E5E97_RS14990	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS14995	ENOG4105E2R	ROK family
E5E97_RS15000	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
E5E97_RS15005	ENOG4108MRH	transcriptional regulatory protein
E5E97_RS15025	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E5E97_RS15030	ENOG4105D0C	transport protein
E5E97_RS15040	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E5E97_RS15050	ENOG4105DQR	SNARE associated Golgi
E5E97_RS15055	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
E5E97_RS15060	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E5E97_RS15065	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
E5E97_RS15070	ENOG4105ED1	spovr family
E5E97_RS15080	ENOG4105CYN	Serine protein kinase
E5E97_RS15085	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E5E97_RS15090	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
E5E97_RS15095	ENOG4105C44	Serine transporter
E5E97_RS15105	ENOG4105CRQ	synthase (Component I)
E5E97_RS15125	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
E5E97_RS15130	ENOG4105C8P	)-transporter
E5E97_RS15135	ENOG4105K63	Thioredoxin
E5E97_RS15140	ENOG4105BZU	Histidine kinase
E5E97_RS15145	ENOG4105BZ1	(ABC) transporter
E5E97_RS15150	ENOG4105BZ1	(ABC) transporter
E5E97_RS15160	ENOG4105WQ3	Rna-binding protein
E5E97_RS15170	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
E5E97_RS15190	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
E5E97_RS15195	ENOG41061CK	Antibiotic biosynthesis monooxygenase
E5E97_RS15225	ENOG4105KK4	UPF0060 membrane protein
E5E97_RS15235	ENOG4105K5X	acetyltransferase
E5E97_RS15240	ENOG4105C1J	atp-dependent rna helicase
E5E97_RS15245	ENOG4108V06	Glutathione peroxidase
E5E97_RS15255	ENOG4105CPF	Cell wall formation (By similarity)
E5E97_RS15265	ENOG4106IUH	DTW domain containing protein
E5E97_RS15270	ENOG4105EJ9	Membrane
E5E97_RS15275	ENOG4105VP0	transcriptional regulator, lysR family
E5E97_RS15290	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
E5E97_RS15345	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E5E97_RS15350	ENOG4105PAD	Hydrolase
E5E97_RS15355	ENOG4105CH2	amidohydrolase
E5E97_RS15360	ENOG4105CTQ	phosphohexokinase
E5E97_RS15370	ENOG4107S90	membrAne
E5E97_RS15375	ENOG4106371	Methyltransferase
E5E97_RS15380	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
E5E97_RS15385	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
E5E97_RS15390	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
E5E97_RS15410	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E5E97_RS15450	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E5E97_RS15480	ENOG4105BZU	Histidine kinase
E5E97_RS15490	ENOG4108DG9	Smr protein MutS2
E5E97_RS15495	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E5E97_RS15500	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E5E97_RS15510	ENOG4105C1J	atp-dependent rna helicase
E5E97_RS15525	ENOG4105E0U	tyrosine-specific transport protein
E5E97_RS15530	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
E5E97_RS15535	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
E5E97_RS15540	ENOG4105DE4	1-phosphofructokinase
E5E97_RS15545	ENOG4105DM4	PTS System
E5E97_RS15555	ENOG4107P2S	Transcriptional regulator
E5E97_RS15570	ENOG4105DAS	pts system
E5E97_RS15575	ENOG4105ETZ	PTS System
E5E97_RS15580	ENOG4105F3R	pts system mannose fructose sorbose family iid
E5E97_RS15585	ENOG4107SZR	mannose-6-phosphate isomerase
E5E97_RS15590	ENOG4105XZD	Fe-S protein
E5E97_RS15595	ENOG4105CA3	membrane-bound lytic murein transglycosylase
E5E97_RS15600	ENOG4105XPH	Ferredoxin
E5E97_RS15605	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E5E97_RS15610	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E5E97_RS15615	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E5E97_RS15620	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E5E97_RS15625	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5E97_RS15645	ENOG4105C22	threonyL-tRNA synthetase
E5E97_RS15650	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
E5E97_RS15655	ENOG41083UC	50s ribosomal protein L35
E5E97_RS15660	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E5E97_RS15665	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E5E97_RS15670	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E5E97_RS15675	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E5E97_RS15680	ENOG4105BZU	Histidine kinase
E5E97_RS15705	ENOG4108KHX	Diguanylate cyclase
E5E97_RS15710	ENOG4105ETE	Transcriptional regulator (LacI family
E5E97_RS15715	ENOG4108RVA	ribokinase
E5E97_RS15720	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
E5E97_RS15725	ENOG4105CNN	ABC, transporter
E5E97_RS15730	ENOG4105C2J	ABC transporter
E5E97_RS15735	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
E5E97_RS15740	ENOG4108RXX	maleylacetoacetate isomerase
E5E97_RS15755	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E5E97_RS15760	ENOG4105Q9Y	Universal stress protein
E5E97_RS15765	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
E5E97_RS15790	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
E5E97_RS15805	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
E5E97_RS15815	ENOG4108ZGC	gaf domain protein
E5E97_RS15820	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
E5E97_RS15825	ENOG4105CN1	protease
E5E97_RS15830	ENOG4105CD8	aminopeptidase N
E5E97_RS15840	ENOG4105C7I	Dehydrogenase
E5E97_RS15845	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E5E97_RS15850	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
E5E97_RS15855	ENOG41079UR	PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity)
E5E97_RS15860	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
E5E97_RS15870	ENOG4105C5H	ABC transporter
E5E97_RS15880	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
E5E97_RS15885	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
E5E97_RS15890	ENOG4105DAN	ATP-dependent protease
E5E97_RS15910	ENOG4105MQ5	zona occludens toxin
E5E97_RS15945	ENOG41067QW	Transcriptional regulator
E5E97_RS15965	ENOG4105MQ5	zona occludens toxin
E5E97_RS16000	ENOG41067QW	Transcriptional regulator
E5E97_RS16020	ENOG4105MQ5	zona occludens toxin
E5E97_RS16050	ENOG4105D70	Integrase catalytic subunit
E5E97_RS16055	ENOG4105F5W	AtP-binding protein
E5E97_RS16070	ENOG41067QW	Transcriptional regulator
E5E97_RS16080	ENOG4105X2V	dna damage-inducible protein
E5E97_RS16130	ENOG4105DXD	2-methylcitrate dehydratase
E5E97_RS16135	ENOG4105BZN	citrate synthase
E5E97_RS16140	ENOG4105CR4	methylisocitrate lyase
E5E97_RS16150	ENOG4105F1S	paraquat-inducible protein a
E5E97_RS16155	ENOG4105DY2	Paraquat-inducible protein b
E5E97_RS16160	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E5E97_RS16175	ENOG4105F8V	Hydrolase, tatD family
E5E97_RS16180	ENOG4107QRG	dna polymerase iii
E5E97_RS16185	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
E5E97_RS16190	ENOG4105HHA	aminodeoxychorismate lyase
E5E97_RS16195	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
E5E97_RS16200	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E5E97_RS16205	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E5E97_RS16210	ENOG4105CHR	reductase
E5E97_RS16215	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E5E97_RS16220	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E5E97_RS16225	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
E5E97_RS16230	ENOG4105VGS	50s ribosomal protein l32
E5E97_RS16235	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
E5E97_RS16245	ENOG4105G2Y	Transcriptional regulator
E5E97_RS16250	ENOG4105CNH	Multidrug resistance protein MdtL
E5E97_RS16255	ENOG4108UHJ	MAF-like protein
E5E97_RS16260	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E5E97_RS16270	ENOG4105C03	ribonuclease
E5E97_RS16275	ENOG4105CJ3	phosphate transporter
E5E97_RS16280	ENOG4105DHP	deoxycytidine triphosphate deaminase
E5E97_RS16285	ENOG4105DBI	uridine monophosphokinase
E5E97_RS16290	ENOG4105D1F	ATP-binding protein
E5E97_RS16295	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E5E97_RS16305	ENOG4108K3A	Glutathione S-transferase
E5E97_RS16310	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
E5E97_RS16315	ENOG4108N3W	hemolysin secretion protein
E5E97_RS16320	ENOG4105DR4	Methyltransferase
E5E97_RS16330	ENOG4105FAT	Acyl-transferase
E5E97_RS16335	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
E5E97_RS16340	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
E5E97_RS16345	ENOG4105C5X	domain protein
E5E97_RS16350	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E97_RS16355	ENOG4105BZU	Histidine kinase
E5E97_RS16360	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E5E97_RS16370	ENOG4105CQ7	ATP-dependent helicase
E5E97_RS16390	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E5E97_RS16395	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E5E97_RS16400	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
E5E97_RS16405	ENOG4105WD1	Membrane
E5E97_RS16410	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
E5E97_RS16420	ENOG4106PMH	Extracellular solute-binding protein family 3
E5E97_RS16425	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
E5E97_RS16430	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E97_RS16435	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E5E97_RS16445	ENOG41072GX	Peptidase M22 Glycoprotease
E5E97_RS16450	ENOG4105DVT	helicase
E5E97_RS16460	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E5E97_RS16465	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E5E97_RS16470	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E5E97_RS16480	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E5E97_RS16485	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E5E97_RS16490	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E97_RS16500	ENOG4105BZU	Histidine kinase
E5E97_RS16505	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E5E97_RS16510	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E5E97_RS16520	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E97_RS16525	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
E5E97_RS16535	ENOG4107MBR	17 kDa surface antigen
E5E97_RS16545	ENOG4108UTP	(2Fe-2S)-binding domain protein
E5E97_RS16550	ENOG4108HR6	Dehydrogenase
E5E97_RS16555	ENOG4105C7W	Xanthine dehydrogenase
E5E97_RS16560	ENOG4105C7N	Xanthine uracil vitamin C permease
E5E97_RS16565	ENOG4107QUY	Guanine deaminase
E5E97_RS16570	ENOG4105C2W	permease
E5E97_RS16575	ENOG4105C7W	Xanthine dehydrogenase
E5E97_RS16580	ENOG410873Y	FAD binding domain in molybdopterin dehydrogenase
E5E97_RS16585	ENOG4107UUR	Chlorohydrolase aminohydrolase
E5E97_RS16590	ENOG4105BZ8	glutamate synthase
E5E97_RS16595	ENOG4105MFX	4-diphosphocytidyl-2c-methyl-d-erythritol synthase
E5E97_RS16600	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
E5E97_RS16605	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
E5E97_RS16610	ENOG4108Q5Y	Membrane
E5E97_RS16615	ENOG4105C5B	carbamate kinase
E5E97_RS16620	ENOG4105CD3	dihydroorotase
E5E97_RS16625	ENOG4107S4Y	M20 DapE family protein YgeY
E5E97_RS16635	ENOG4105IW6	Carbamoyltransferase
E5E97_RS16640	ENOG4108JUB	Transcriptional regulator
E5E97_RS16680	ENOG4108VWS	Yaeq family
E5E97_RS16690	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5E97_RS16695	ENOG4105CHU	acetyl-coa acetyltransferase
E5E97_RS16700	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E5E97_RS16730	ENOG4105EMN	RNA polymerase sigma factor
E5E97_RS16740	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
E5E97_RS16745	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
E5E97_RS16750	ENOG4105D58	Diguanylate phosphodiesterase
E5E97_RS16755	ENOG4105CHU	acetyl-coa acetyltransferase
E5E97_RS16770	ENOG4105NBK	UPF0345 protein
E5E97_RS16775	ENOG4105EJQ	L-serine dehydratase
E5E97_RS16780	ENOG4105EJQ	L-serine dehydratase
E5E97_RS16785	ENOG4105CVE	Lytic murein transglycosylase
E5E97_RS16790	ENOG4105VNG	YcgL domain-containing protein
E5E97_RS16795	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
E5E97_RS16800	ENOG4107QMS	site-determining protein
E5E97_RS16810	ENOG4108W5H	UPF0263 protein
E5E97_RS16815	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
E5E97_RS16820	ENOG4105XW2	UPF0263 protein
E5E97_RS16855	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E5E97_RS16860	ENOG4108SXK	Transporter Drug Metabolite Exporter family
E5E97_RS16865	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
E5E97_RS16870	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
E5E97_RS16880	ENOG4108R6K	riboflavin synthase, subunit alpha
E5E97_RS16885	ENOG4105W1I	UPF0253 protein
E5E97_RS16945	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
E5E97_RS16950	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
E5E97_RS16960	ENOG4105DUM	transcriptional regulator, lysR family
E5E97_RS16970	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
E5E97_RS16975	ENOG4105CBN	LysR family transcriptional regulator
E5E97_RS16985	ENOG4105DHT	Metal Dependent Phosphohydrolase
E5E97_RS16995	ENOG4105BZU	Histidine kinase
E5E97_RS17000	ENOG4105CS2	ec 3.2.1.21
E5E97_RS17005	ENOG4108KB2	LysR family Transcriptional regulator
E5E97_RS17010	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
E5E97_RS17035	ENOG4105HF0	Membrane
E5E97_RS17040	ENOG4105D5Q	Arginine ornithine antiporter
E5E97_RS17050	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E5E97_RS17055	ENOG4105E39	Enoyl-CoA hydratase
E5E97_RS17065	ENOG4105C1G	acyl-Coa dehydrogenase
E5E97_RS17070	ENOG4105C26	Dehydrogenase
E5E97_RS17075	ENOG4105C1G	acyl-Coa dehydrogenase
E5E97_RS17080	ENOG4107QX3	carboxylase
E5E97_RS17095	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
E5E97_RS17115	ENOG4106HK8	GPR1 FUN34 yaaH family protein
E5E97_RS17130	ENOG4105BZG	amino acid carrier protein
E5E97_RS17135	ENOG41060WC	Enoyl-CoA hydratase
E5E97_RS17150	ENOG41062QD	Membrane
E5E97_RS17155	ENOG4107QN1	sodium solute
E5E97_RS17160	ENOG4105C5H	ABC transporter
E5E97_RS17165	ENOG4105EIN	peptidylprolyl cis-trans isomerase
E5E97_RS17170	ENOG4105K70	DNA-binding protein
E5E97_RS17175	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E5E97_RS17180	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E5E97_RS17185	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E5E97_RS17190	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E5E97_RS17205	ENOG4105D60	lipoprotein releasing system transmembrane protein
E5E97_RS17210	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E5E97_RS17215	ENOG4105D60	lipoprotein releasing system transmembrane protein
E5E97_RS17225	ENOG4108JA2	transcriptioN-repair coupling factor
E5E97_RS17230	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E5E97_RS17235	ENOG4108J59	Extracellular solute-binding protein, family 5
E5E97_RS17240	ENOG4108IPJ	Membrane
E5E97_RS17250	ENOG4108BY2	phosphohistidine phosphatase
E5E97_RS17255	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
E5E97_RS17260	ENOG4105FQ6	thiopurine methyltransferase
E5E97_RS17305	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E5E97_RS17310	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E5E97_RS17315	ENOG4105DFH	Transport of potassium into the cell (By similarity)
E5E97_RS17340	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E5E97_RS17345	ENOG4105D4P	Coproporphyrinogen iii oxidase
E5E97_RS17350	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS17355	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5E97_RS17360	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E5E97_RS17365	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E5E97_RS17370	ENOG4105C10	Electron transfer flavoprotein
E5E97_RS17375	ENOG4105BZJ	Electron transfer flavoprotein
E5E97_RS17380	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E5E97_RS17390	ENOG4105QZU	Inner membrane protein YfeZ
E5E97_RS17405	ENOG4105D05	Receptor
E5E97_RS17410	ENOG4105DQ5	transport system permease protein
E5E97_RS17415	ENOG4105TVJ	transport system, permease
E5E97_RS17420	ENOG4105E0A	ABC, transporter
E5E97_RS17425	ENOG4108TSE	Transferase
E5E97_RS17430	ENOG4108MES	Periplasmic binding protein
E5E97_RS17435	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E97_RS17445	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
E5E97_RS17450	ENOG4105CEY	Amp-dependent synthetase and ligase
E5E97_RS17455	ENOG4105WQI	isochorismatase
E5E97_RS17460	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
E5E97_RS17470	ENOG4105F3T	(LipO)protein
E5E97_RS17480	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E5E97_RS17485	ENOG4105BZU	Histidine kinase
E5E97_RS17500	ENOG4107RE1	Inosine-guanosine kinase
E5E97_RS17510	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
E5E97_RS17515	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E5E97_RS17520	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E5E97_RS17525	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E5E97_RS17530	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E5E97_RS17550	ENOG4108RC0	Electron transport protein
E5E97_RS17560	ENOG4105DFH	Transport of potassium into the cell (By similarity)
E5E97_RS17565	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
E5E97_RS17570	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E5E97_RS17575	ENOG4107TDF	Formate hydrogenlyase subunit 4
E5E97_RS17590	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
E5E97_RS17595	ENOG4105I6X	formate hydrogenlyase maturation
E5E97_RS17610	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
E5E97_RS17625	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
E5E97_RS17630	ENOG4105CQS	hydrogenase expression formation protein HypD
E5E97_RS17635	ENOG4105C45	hydrogenase expression formation protein (HypE)
E5E97_RS17640	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
E5E97_RS17645	ENOG4107RSS	Hydrogenase accessory protein HypB
E5E97_RS17650	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
E5E97_RS17655	ENOG4105C3U	ABC transporter
E5E97_RS17660	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E5E97_RS17665	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E5E97_RS17675	ENOG4108WGS	hydrogenase 2-specific chaperone
E5E97_RS17680	ENOG4108USZ	hydrogenase
E5E97_RS17685	ENOG4105DPX	Hydrogenase, large subunit
E5E97_RS17690	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
E5E97_RS17695	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E5E97_RS17700	ENOG4105E3S	small subunit
E5E97_RS17705	ENOG4108VYJ	response regulator receiver protein
E5E97_RS17715	ENOG4105CBS	Chea signal transduction histidine kinase
E5E97_RS17720	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS17725	ENOG4108V3W	Chemotaxis protein, CheW
E5E97_RS17730	ENOG4105BZU	Histidine kinase
E5E97_RS17735	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E5E97_RS17740	ENOG4105BZU	Histidine kinase
E5E97_RS17745	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS17785	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E5E97_RS17830	ENOG4105CHH	sulfate transporter
E5E97_RS17880	ENOG4105C2C	drug resistance transporter, Bcr CflA
E5E97_RS17890	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E5E97_RS17920	ENOG4107QR9	Iron-sulfur cluster binding protein
E5E97_RS17930	ENOG4105DAA	L-lactate
E5E97_RS17935	ENOG4105CR8	Transcriptional regulator
E5E97_RS17945	ENOG4108UYE	Lactoylglutathione lyase
E5E97_RS17950	ENOG4105F2Z	3-oxoadipate enol-lactonase
E5E97_RS17970	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E5E97_RS17980	ENOG4105CFH	Aspartokinase
E5E97_RS17990	ENOG4107T7U	Sulfatase
E5E97_RS17995	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
E5E97_RS18015	ENOG4105K8R	UPF0145 protein
E5E97_RS18035	ENOG4105CEP	NADH dehydrogenase
E5E97_RS18040	ENOG4105D0Y	UPF0227 protein
E5E97_RS18050	ENOG4105DPN	Oligoendopeptidase f
E5E97_RS18055	ENOG4105DPN	Oligoendopeptidase f
E5E97_RS18060	ENOG4105CKW	Inner membrane protein yedI
E5E97_RS18070	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5E97_RS18075	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5E97_RS18110	ENOG4105K59	histidine triad (HIT) protein
E5E97_RS18115	ENOG4108NVR	Methyl-accepting chemotaxis
E5E97_RS18125	ENOG4105CD3	dihydroorotase
E5E97_RS18140	ENOG4105CK2	sodium dicarboxylate symporter
E5E97_RS18150	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E5E97_RS18155	ENOG4105DU1	integral membrane protein, terc
E5E97_RS18160	ENOG4108JQ7	(ABC) transporter
E5E97_RS18165	ENOG4105C3U	ABC transporter
E5E97_RS18170	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E5E97_RS18175	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E5E97_RS18180	ENOG4107QSI	ABC, transporter
E5E97_RS18185	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
E5E97_RS18195	ENOG4105C0A	alcohol dehydrogenase
E5E97_RS18200	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E5E97_RS18205	ENOG4108HRK	Histidine kinase
E5E97_RS18210	ENOG4108NEV	two component transcriptional regulator, LytTR family
E5E97_RS18220	ENOG4105KK7	inner membrane protein YiaW
E5E97_RS18225	ENOG4105EFX	secretion protein, HlyD family
E5E97_RS18230	ENOG4105CFI	type iii restriction protein res subunit
E5E97_RS18235	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
E5E97_RS18240	ENOG41090BQ	Glutaredoxin
E5E97_RS18250	ENOG4105CHM	Aminotransferase
E5E97_RS18255	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
E5E97_RS18260	ENOG4105RKW	reductase (By
E5E97_RS18265	ENOG4107SDU	Methyl-accepting chemotaxis
E5E97_RS18275	ENOG4108PCN	EamA-like transporter family
E5E97_RS18280	ENOG4105DGN	Electron transport complex
E5E97_RS18285	ENOG4108R3D	Electron transport complex
E5E97_RS18295	ENOG4105D6A	Electron transport complex
E5E97_RS18310	ENOG4105CSM	endonuclease III
E5E97_RS18315	ENOG4108UYE	Lactoylglutathione lyase
E5E97_RS18320	ENOG4105EIY	sodium-type flagellar protein motY
E5E97_RS18330	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
E5E97_RS18335	ENOG4105D3Y	Na H antiporter
E5E97_RS18345	ENOG4105KA0	thioesterase Superfamily protein
E5E97_RS18355	ENOG4105CQB	FAD linked oxidase domain protein
E5E97_RS18365	ENOG4105EE5	Membrane protein terC
E5E97_RS18370	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5E97_RS18380	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
E5E97_RS18385	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E5E97_RS18395	ENOG4105CAQ	asparagine synthetase
E5E97_RS18405	ENOG4108TGY	Glutathione S-transferase
E5E97_RS18410	ENOG4108RXX	maleylacetoacetate isomerase
E5E97_RS18420	ENOG4105F1J	Homogentisate 1,2-dioxygenase
E5E97_RS18425	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
E5E97_RS18435	ENOG4108W1A	pseudouridine synthase
E5E97_RS18440	ENOG410620I	Diguanylate cyclase
E5E97_RS18445	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E5E97_RS18455	ENOG4105FF5	Membrane
E5E97_RS18460	ENOG4105DIJ	Phosphoethanolamine transferase
E5E97_RS18480	ENOG4108MN8	Membrane
E5E97_RS18485	ENOG4105EM2	membrane
E5E97_RS18490	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
E5E97_RS18495	ENOG4108S3P	Sporulation domain protein
E5E97_RS18500	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E5E97_RS18505	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E5E97_RS18510	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E5E97_RS18520	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E5E97_RS18525	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
E5E97_RS18530	ENOG4105EYK	Phosphatidylglycerophosphatase B
E5E97_RS18535	ENOG4105D01	(LipO)protein
E5E97_RS18575	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
E5E97_RS18580	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
E5E97_RS18590	ENOG4105C85	amino acid
E5E97_RS18640	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
E5E97_RS18650	ENOG4105N5T	Radical SAM Protein
E5E97_RS18655	ENOG4105CBC	glutamate synthase
E5E97_RS18660	ENOG4105BZ8	glutamate synthase
E5E97_RS18665	ENOG4105CDA	abc transporter atp-binding protein
E5E97_RS18670	ENOG4105DRP	amino acid AbC transporter
E5E97_RS18675	ENOG4105EAB	amino acid AbC transporter
E5E97_RS18715	ENOG4105C1J	atp-dependent rna helicase
E5E97_RS18720	ENOG4108MK9	spermidine N(1)-acetyltransferase
E5E97_RS18750	ENOG4107QS8	(LipO)protein
E5E97_RS18755	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E5E97_RS18760	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E5E97_RS18765	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E5E97_RS18770	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E5E97_RS18780	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E5E97_RS18785	ENOG4105E66	phosphoriboisomerase A
E5E97_RS18790	ENOG4108JQ1	Dehydrogenase
E5E97_RS18795	ENOG41080IJ	Diacylglycerol kinase
E5E97_RS18800	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5E97_RS18810	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
E5E97_RS18815	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
E5E97_RS18820	ENOG4105BZU	Histidine kinase
E5E97_RS18830	ENOG4105CZX	twitching motility protein
E5E97_RS18835	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E5E97_RS18860	ENOG4108ZJT	translation initiation factor, Sui1
E5E97_RS18895	ENOG410620I	Diguanylate cyclase
E5E97_RS18910	ENOG41090JH	(ATPase)-like protein
E5E97_RS18920	ENOG4105C8N	cysteinyl-tRNA synthetase
E5E97_RS18925	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E5E97_RS18935	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
E5E97_RS18940	ENOG4105DVI	reductase, NrfD
E5E97_RS18945	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E5E97_RS18950	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
E5E97_RS18975	ENOG4108NVR	Methyl-accepting chemotaxis
E5E97_RS18980	ENOG4107SDU	Methyl-accepting chemotaxis
E5E97_RS19025	ENOG4105WH1	Two component transcriptional regulator luxr family
E5E97_RS19030	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
E5E97_RS19035	ENOG4105W49	UPF0434 protein
E5E97_RS19040	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E5E97_RS19050	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
E5E97_RS19065	ENOG4105D7A	ATP-binding protein
E5E97_RS19070	ENOG4105CGF	Aromatic amino acid aminotransferase
E5E97_RS19085	ENOG4105DVT	helicase
E5E97_RS19095	ENOG4105DGU	Histone deacetylase
E5E97_RS19100	ENOG4108ISG	Major Facilitator
E5E97_RS19105	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
E5E97_RS19130	ENOG4105NXH	GreA GreB family elongation factor
E5E97_RS19135	ENOG4108KX4	response regulator
E5E97_RS19140	ENOG4105BZU	Histidine kinase
E5E97_RS19145	ENOG4105CXY	transporter
E5E97_RS19155	ENOG4106TNF	Periplasmic binding protein
E5E97_RS19160	ENOG4105E5Q	amino acid AbC transporter
E5E97_RS19185	ENOG4105D5Q	Arginine ornithine antiporter
E5E97_RS19190	ENOG4105C3R	Methionine synthase
E5E97_RS19200	ENOG4105C37	(CBS) domain
E5E97_RS19210	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E5E97_RS19215	ENOG4105E2Z	phosphate ABC transporter (Permease
E5E97_RS19220	ENOG4105C8U	phosphate abc transporter
E5E97_RS19225	ENOG4108Z6B	deaminase
E5E97_RS19245	ENOG4107QP3	malate synthase g
E5E97_RS19250	ENOG4108I9X	Isocitrate lyase
E5E97_RS19255	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
E5E97_RS19265	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
E5E97_RS19270	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E5E97_RS19275	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E5E97_RS19280	ENOG4107QNR	UPF0135 protein
E5E97_RS19290	ENOG4105BZU	Histidine kinase
E5E97_RS19305	ENOG4105RH4	Glycine cleavage system transcriptional repressor
E5E97_RS19310	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
E5E97_RS19315	ENOG4105C9X	ppx gppa phosphatase
E5E97_RS19320	ENOG4105CJW	magnesium transporter
E5E97_RS19325	ENOG4105DTJ	flagellar hook-associated protein
E5E97_RS19335	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
E5E97_RS19340	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E5E97_RS19345	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E5E97_RS19350	ENOG4105CGA	flagellar basal-body rod protein FlgG
E5E97_RS19355	ENOG4108KPB	Flagellar basal-body rod protein FlgF
E5E97_RS19360	ENOG4105BZE	flagellar hook protein, FlgE
E5E97_RS19370	ENOG4108ZC9	flagellar basal-body rod protein flgc
E5E97_RS19375	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
E5E97_RS19380	ENOG4105BZU	Histidine kinase
E5E97_RS19390	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
E5E97_RS19405	ENOG4108RE9	Phosphodiesterase
E5E97_RS19410	ENOG4107QSI	ABC, transporter
E5E97_RS19420	ENOG4105I08	Pseudouridine synthase
E5E97_RS19425	ENOG4105CPI	Metal Dependent Phosphohydrolase
E5E97_RS19435	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E5E97_RS19440	ENOG4105F1A	Pyruvate formate-lyase
E5E97_RS19450	ENOG4105N2W	Transcriptional regulator
E5E97_RS19485	ENOG4105VEQ	Cold shock protein
E5E97_RS19490	ENOG4107QSN	dihydrolipoamide acetyltransferase
E5E97_RS19495	ENOG4105CPP	Dehydrogenase, E1 component
E5E97_RS19500	ENOG4107RUY	(E1 component), alpha subunit
E5E97_RS19515	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
E5E97_RS19525	ENOG4108YXG	UPF0502 protein
E5E97_RS19535	ENOG4108KPN	Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12)
E5E97_RS19540	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
E5E97_RS19550	ENOG4106ECQ	phosphomannomutase
E5E97_RS19555	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
E5E97_RS19565	ENOG4108UW5	maltose o-acetyltransferase
E5E97_RS19585	ENOG4108UW5	maltose o-acetyltransferase
E5E97_RS19590	ENOG4108UW5	maltose o-acetyltransferase
E5E97_RS19605	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E5E97_RS19610	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
E5E97_RS19620	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E5E97_RS19625	ENOG4105BZS	acriflavin resistance protein
E5E97_RS19630	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E5E97_RS19635	ENOG4108IG5	Transcriptional regulator
E5E97_RS19655	ENOG4105C29	acyl-CoA thioesterase
E5E97_RS19660	ENOG4105FE9	pseudouridine synthase
E5E97_RS19665	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E5E97_RS19675	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E5E97_RS19680	ENOG4105DB7	PHP domain protein
E5E97_RS19685	ENOG4105CRQ	synthase (Component I)
E5E97_RS19690	ENOG4108EFP	Anthranilate synthase component II
E5E97_RS19695	ENOG4108I0Q	anthranilate phosphoribosyltransferase
E5E97_RS19700	ENOG4105DK0	Indole-3-glycerol phosphate synthase
E5E97_RS19705	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E5E97_RS19710	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E5E97_RS19760	ENOG4105D9N	nucleoside
E5E97_RS19770	ENOG4105HVQ	Regulatory factor of maltose metabolism
E5E97_RS19775	ENOG4106YXT	transposase
E5E97_RS19780	ENOG4108WTW	DNA transposition protein
E5E97_RS19905	ENOG4108Z6H	mu-like prophage Flumu protein gp27
E5E97_RS19910	ENOG4105CF2	Mu-like prophage FluMu protein GP28
E5E97_RS19915	ENOG4105QIB	mu-like prophage Flumu protein gp29
E5E97_RS19930	ENOG4105EFV	Major head subunit
E5E97_RS19970	ENOG4105TKZ	Tail Sheath
E5E97_RS20000	ENOG4105PZ7	Baseplate assembly protein
E5E97_RS20010	ENOG4108T86	baseplate J family protein
E5E97_RS20040	ENOG4106FTQ	Taurine ABC transporter, periplasmic
E5E97_RS20045	ENOG4108ETV	ABC transporter
E5E97_RS20050	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
E5E97_RS20055	ENOG4105E2B	Taurine dioxygenase
E5E97_RS20065	ENOG4107RDB	Major Facilitator
E5E97_RS20070	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
E5E97_RS20075	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
E5E97_RS20080	ENOG4105CCU	oxidase (Subunit III)
E5E97_RS20085	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E5E97_RS20090	ENOG4105E2S	oxidase) subunit II
E5E97_RS20140	ENOG4105E5W	Transporter
E5E97_RS20155	ENOG4105CGK	Exodeoxyribonuclease III
E5E97_RS20175	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
E5E97_RS20180	ENOG4108IJF	Heavy metal efflux pump, CzcA
E5E97_RS20200	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
E5E97_RS20205	ENOG4105BZU	Histidine kinase
E5E97_RS20230	ENOG41080HT	Transcriptional regulator, arsr family
E5E97_RS20250	ENOG4105WBN	Transcriptional regulator (LacI family
E5E97_RS20265	ENOG4105D7K	pfkb domain protein
E5E97_RS20275	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E5E97_RS20280	ENOG4105CFG	Acts as a chaperone (By similarity)
E5E97_RS20285	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E5E97_RS20290	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E5E97_RS20295	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E5E97_RS20310	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E5E97_RS20315	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5E97_RS20320	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E5E97_RS20325	ENOG4105Q26	Siderophore-interacting protein
E5E97_RS20330	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5E97_RS20335	ENOG4108YX2	DNA-binding protein
E5E97_RS20350	ENOG4105KAF	membrAne
E5E97_RS20370	ENOG4105CJP	fad dependent oxidoreductase
E5E97_RS20375	ENOG4107VRI	Transcriptional regulator
E5E97_RS20380	ENOG4105C26	Dehydrogenase
E5E97_RS20385	ENOG4108JPW	Aminotransferase
E5E97_RS20390	ENOG4105CUB	amino acid
E5E97_RS20400	ENOG4105CUB	amino acid
E5E97_RS20415	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E5E97_RS20420	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E5E97_RS20425	ENOG4105BZU	Histidine kinase
E5E97_RS20440	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
E5E97_RS20460	ENOG4105C5H	ABC transporter
E5E97_RS20465	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
E5E97_RS20470	ENOG4105D98	threonine synthase
E5E97_RS20475	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
E5E97_RS20485	ENOG4106FVC	RNA methyltransferase
E5E97_RS20490	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
E5E97_RS20505	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E5E97_RS20515	ENOG41065U4	response regulator
E5E97_RS20530	ENOG4108JJ9	ABC, transporter
E5E97_RS20535	ENOG4108JJ8	(ABC) transporter
E5E97_RS20555	ENOG4108R96	Methyltransferase, YaeB family
E5E97_RS20570	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5E97_RS20575	ENOG4105C6T	cysteine synthase
E5E97_RS20580	ENOG4105KZ7	phosphocarrier protein hpr
E5E97_RS20585	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
E5E97_RS20590	ENOG4105C5Y	PTS System
E5E97_RS20605	ENOG4105CPW	cytochrome b561
E5E97_RS20615	ENOG4105EYH	Exonuclease
E5E97_RS20620	ENOG4105EYH	Exonuclease
E5E97_RS20625	ENOG4107RH8	nuclease SbcCD subunit D
E5E97_RS20635	ENOG4105DH7	May be involved in recombination (By similarity)
E5E97_RS20650	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E5E97_RS20660	ENOG4105CA9	Pyruvate kinase
E5E97_RS20665	ENOG4105EGS	Mechanosensitive ion channel
E5E97_RS20675	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
E5E97_RS20680	ENOG4105C2W	permease
E5E97_RS20695	ENOG4107R1I	NAD-dependent malic enzyme
E5E97_RS20710	ENOG4105QAX	Iron-sulfur
E5E97_RS20715	ENOG4108IEG	Formate dehydrogenase Alpha subunit
E5E97_RS20715	ENOG4108IEG	Formate dehydrogenase Alpha subunit
E5E97_RS20750	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E5E97_RS20755	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
E5E97_RS20760	ENOG4105BZU	Histidine kinase
E5E97_RS20765	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5E97_RS20775	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
E5E97_RS20780	ENOG4108IUZ	ABC transporter
E5E97_RS20785	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
E5E97_RS20790	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E5E97_RS20795	ENOG4105DR8	Membrane
E5E97_RS20800	ENOG4108ESY	Metal dependent phosphohydrolase
E5E97_RS20810	ENOG4107SDU	Methyl-accepting chemotaxis
E5E97_RS20845	ENOG4105XIQ	Protein of unknown function (DUF2517)
E5E97_RS20870	ENOG4108J59	Extracellular solute-binding protein, family 5
E5E97_RS20880	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E5E97_RS20890	ENOG4108JQ7	(ABC) transporter
E5E97_RS20900	ENOG4105RD7	BadF BadG BcrA BcrD
E5E97_RS20910	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E5E97_RS20925	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E5E97_RS20930	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
E5E97_RS20935	ENOG4105ERU	peptidase
E5E97_RS20940	ENOG4105UBK	short-chain dehydrogenase reductase
E5E97_RS20945	ENOG4105C5Q	Transcriptional regulator
E5E97_RS20955	ENOG4105C87	Aminotransferase class I and II
E5E97_RS20970	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E5E97_RS20975	ENOG4108V1U	phospholipid-binding protein
E5E97_RS20985	ENOG4107WCA	isomerase
E5E97_RS20990	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E5E97_RS20995	ENOG4105DR5	peptidase
E5E97_RS21000	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
E5E97_RS21005	ENOG4105TMR	Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity)
E5E97_RS21010	ENOG4105KME	endoribonuclease L-psp
E5E97_RS21020	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E5E97_RS21025	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E5E97_RS21030	ENOG4105GPY	SprT protein
E5E97_RS21055	ENOG4108UJU	UPF0301 protein
E5E97_RS21060	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E5E97_RS21075	ENOG4105G2Y	Transcriptional regulator
E5E97_RS21090	ENOG41066YJ	Beta-lactamase
E5E97_RS21095	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E5E97_RS21110	ENOG4105BZG	amino acid carrier protein
E5E97_RS21115	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E5E97_RS21130	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E5E97_RS21135	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
E5E97_RS21140	ENOG4105CK2	sodium dicarboxylate symporter
E5E97_RS21145	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
E5E97_RS21150	ENOG41063JG	Transcriptional regulator
E5E97_RS21160	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E5E97_RS21165	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E5E97_RS21170	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E5E97_RS21175	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
E5E97_RS21180	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
E5E97_RS21190	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E5E97_RS21195	ENOG4105CGH	5'-nucleotidase
E5E97_RS21200	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
E5E97_RS21205	ENOG4105C3G	gtp-binding protein
E5E97_RS21250	ENOG4107QWE	)-transporter
E5E97_RS21255	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
E5E97_RS21260	ENOG4107SXA	Phosphorylase
E5E97_RS21270	ENOG41060QA	UPF0267 protein
E5E97_RS21280	ENOG4105CG3	alpha amylase, catalytic region
E5E97_RS21290	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
E5E97_RS21305	ENOG4106YXT	transposase
E5E97_RS21310	ENOG4108WTW	DNA transposition protein
E5E97_RS21445	ENOG4108Z6H	mu-like prophage Flumu protein gp27
E5E97_RS21450	ENOG4105CF2	Mu-like prophage FluMu protein GP28
E5E97_RS21455	ENOG4105QIB	mu-like prophage Flumu protein gp29
E5E97_RS21470	ENOG4105EFV	Major head subunit
E5E97_RS21510	ENOG4105TKZ	Tail Sheath
E5E97_RS21525	ENOG4108NYK	Tape measure protein
E5E97_RS21540	ENOG4105PZ7	Baseplate assembly protein
E5E97_RS21550	ENOG4108T86	baseplate J family protein
E5E97_RS21570	ENOG4107VXZ	Hydrolase
E5E97_RS21620	ENOG4105C26	Dehydrogenase
E5E97_RS21630	ENOG4105C8Y	Acetylornithine aminotransferase
E5E97_RS21645	ENOG4105C31	Tryptophanyl-tRNA synthetase
E5E97_RS21655	ENOG4105DJV	ribulose-phosphate 3-epimerase
E5E97_RS21665	ENOG4105DFE	Dna adenine methylase
E5E97_RS21675	ENOG4105D49	3-dehydroquinate synthase
E5E97_RS21680	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E5E97_RS21710	ENOG4108JQC	penicillin-binding protein 1A
E5E97_RS21715	ENOG4105C5Q	Transcriptional regulator
E5E97_RS21720	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS21735	ENOG4105EJC	lysr family transcriptional regulator
E5E97_RS21750	ENOG4105DR5	peptidase
E5E97_RS21760	ENOG4105EGS	Mechanosensitive ion channel
E5E97_RS21765	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
E5E97_RS21770	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS21780	ENOG4105E33	succinate dehydrogenase
E5E97_RS21785	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
E5E97_RS21790	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
E5E97_RS21810	ENOG4105T0Z	Conserved Protein
E5E97_RS21845	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E5E97_RS21850	ENOG4105DHQ	Histidine kinase
E5E97_RS21860	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E5E97_RS21870	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E5E97_RS21875	ENOG4108R5S	membrane
E5E97_RS21885	ENOG4105C5I	Dehydrogenase
E5E97_RS21905	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
E5E97_RS21920	ENOG4105BZU	Histidine kinase
E5E97_RS21930	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
E5E97_RS21935	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E5E97_RS21940	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E5E97_RS21945	ENOG4105C9A	Phoh family
E5E97_RS21950	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E5E97_RS21955	ENOG4108JU5	Magnesium and cobalt efflux protein
E5E97_RS21960	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E5E97_RS21965	ENOG4107PAI	alpha helical protein
E5E97_RS21970	ENOG4105C8T	Leucyl-tRNA synthetase
E5E97_RS21990	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
E5E97_RS21995	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
E5E97_RS22000	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E5E97_RS22005	ENOG4105CJN	penicillin-binding protein
E5E97_RS22010	ENOG4105CNI	cell division protein FtsW
E5E97_RS22015	ENOG4105CNI	cell division protein FtsW
E5E97_RS22020	ENOG4105CVE	Lytic murein transglycosylase
E5E97_RS22025	ENOG4105K6T	rare lipoprotein A
E5E97_RS22030	ENOG4105DZ1	carboxypeptidase
E5E97_RS22035	ENOG4108Z43	UPF0250 protein
E5E97_RS22040	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E5E97_RS22045	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E5E97_RS22055	ENOG4105MJ9	esterase
E5E97_RS22060	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
E5E97_RS22075	ENOG4107SWG	transcriptional regulator MERR family
E5E97_RS22080	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E5E97_RS22085	ENOG4105T95	Thiol disulfide interChange protein
E5E97_RS22090	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E5E97_RS22095	ENOG4105BZU	Histidine kinase
E5E97_RS22100	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5E97_RS22105	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
E5E97_RS22125	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E5E97_RS22155	ENOG4105DB1	molybdopterin oxidoreductase
E5E97_RS22160	ENOG4106WHD	Tetrathionate reductase
E5E97_RS22165	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
E5E97_RS22175	ENOG4108ZXC	Two component transcriptional regulator, luxr family
E5E97_RS22180	ENOG4108HRK	Histidine kinase
E5E97_RS22185	ENOG4108NEV	two component transcriptional regulator, LytTR family
E5E97_RS22195	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
E5E97_RS22210	ENOG41090EX	DsrE family
E5E97_RS22215	ENOG4105BZU	Histidine kinase
E5E97_RS22220	ENOG4105E5W	Transporter
E5E97_RS22225	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E5E97_RS22230	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E5E97_RS22235	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E5E97_RS22240	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E5E97_RS22245	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
E5E97_RS22250	ENOG4105CHV	Transcription elongation factor NusA
E5E97_RS22255	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
E5E97_RS22270	ENOG4105NTZ	Preprotein translocase subunit SecG
E5E97_RS22275	ENOG4105CP7	Triose-phosphate isomerase
E5E97_RS22280	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E5E97_RS22285	ENOG4105EEI	dihydropteroate synthase
E5E97_RS22290	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E5E97_RS22295	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
E5E97_RS22300	ENOG4105HBR	Rna-binding protein
E5E97_RS22310	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E5E97_RS22315	ENOG4107XSU	flagellar motor protein motb
E5E97_RS22320	ENOG4105E14	MotA TolQ exbB proton channel
E5E97_RS22325	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E5E97_RS22330	ENOG4105CTB	Polyprenyl synthetase
E5E97_RS22335	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E5E97_RS22345	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E5E97_RS22355	ENOG4108JQ6	ABC transporter
E5E97_RS22360	ENOG4108ZAI	phosphatidylglycerophosphatase a
E5E97_RS22365	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E5E97_RS22370	ENOG4107YIM	Involved in the transcription termination process (By similarity)
E5E97_RS22375	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E5E97_RS22395	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E5E97_RS22400	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
E5E97_RS22410	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E5E97_RS22425	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
E5E97_RS22455	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5E97_RS22460	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E5E97_RS22465	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E5E97_RS22470	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E5E97_RS22480	ENOG4108IA2	Sodium pantothenate symporter
E5E97_RS22485	ENOG4105CI1	PTS System
E5E97_RS22490	ENOG4105HEI	LysR family (Transcriptional regulator
E5E97_RS22495	ENOG4105CIS	alcohol dehydrogenase
E5E97_RS22500	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E5E97_RS22515	ENOG41069NU	Nitroreductase
E5E97_RS22520	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5E97_RS22525	ENOG4105D07	Signal peptide peptidase, SppA
E5E97_RS22545	ENOG4105VUT	cytoplasmic protein
E5E97_RS22550	ENOG4105HDK	L-asparaginase
E5E97_RS22555	ENOG4105D6U	Sodium Glutamate Symporter
E5E97_RS22560	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS22570	ENOG4105CRK	lysyL-tRNA synthetase
E5E97_RS22575	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
E5E97_RS22580	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
E5E97_RS22585	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
E5E97_RS22590	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
E5E97_RS22595	ENOG4105GIJ	Glycine betaine
E5E97_RS22600	ENOG4108HQS	Glycine betaine
E5E97_RS22605	ENOG4108IJ7	Glycine betaine
E5E97_RS22630	ENOG4107XM3	UPF0442 protein
E5E97_RS22635	ENOG4105DWK	Membrane
E5E97_RS22645	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E5E97_RS22655	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E5E97_RS22660	ENOG4105C2D	reductase
E5E97_RS22670	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E5E97_RS22695	ENOG4105C84	Histidine ammonia-lyase
E5E97_RS22725	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E5E97_RS22760	ENOG4105CA0	peroxidase
E5E97_RS22775	ENOG4105DD7	kinase (PfkB family
E5E97_RS22780	ENOG4107QZF	nitrite reductase NADPH large subunit
E5E97_RS22785	ENOG4107QZF	nitrite reductase NADPH large subunit
E5E97_RS22790	ENOG4105D7T	ABC transporter
E5E97_RS22795	ENOG4105DG7	nitrate ABC transporter
E5E97_RS22800	ENOG4105D7T	ABC transporter
E5E97_RS22810	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E5E97_RS22845	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E5E97_RS22855	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
E5E97_RS22860	ENOG4105V1F	Fermentation respiration switch protein
E5E97_RS22865	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
E5E97_RS22870	ENOG4105CIN	aminoacyl-histidine dipeptidase
E5E97_RS22875	ENOG4108JQ7	(ABC) transporter
E5E97_RS22890	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
E5E97_RS22895	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
E5E97_RS22900	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E5E97_RS22920	ENOG4109015	Biopolymer transport protein exbD tolR
E5E97_RS22970	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E5E97_RS22975	ENOG4105C8Q	Methyl-accepting chemotaxis
E5E97_RS22985	ENOG4105VEQ	Cold shock protein
E5E97_RS23025	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E5E97_RS23030	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E5E97_RS23035	ENOG4105DJ4	phosphatidylserine decarboxylase
E5E97_RS23040	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
E5E97_RS23055	ENOG4108KBJ	Inner membrane protein YkgB
E5E97_RS23065	ENOG4108K01	transcriptional regulator
E5E97_RS23075	ENOG4105BZU	Histidine kinase
E5E97_RS23080	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
E5E97_RS23105	ENOG4105BZ1	(ABC) transporter
E5E97_RS23110	ENOG4105SUV	lipoprotein YgdR
E5E97_RS23120	ENOG4107RM6	sulfurtransferase
E5E97_RS23125	ENOG4105CSV	Glutaminase
E5E97_RS23130	ENOG41090ED	Protein with unknown function (DUF469)
E5E97_RS23135	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E5E97_RS23140	ENOG4105IIU	Aminopeptidase
E5E97_RS23145	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E5E97_RS23150	ENOG4105BZU	Histidine kinase
E5E97_RS23155	ENOG4105ECP	epimerase
E5E97_RS23160	ENOG4105CV6	ABC transporter, permease
E5E97_RS23165	ENOG4108I0Y	(ABC) transporter
E5E97_RS23170	ENOG4108UJV	acyl-CoA thioesterase i
E5E97_RS23185	ENOG4105D0C	transport protein
E5E97_RS23190	ENOG4108UT2	hemolysin iii
E5E97_RS23195	ENOG4105DY8	decarboxylase
E5E97_RS23200	ENOG4107835	probably involved in intracellular septation (By similarity)
E5E97_RS23205	ENOG4105K9H	YciI-like protein
E5E97_RS23210	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E5E97_RS23215	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
E5E97_RS23220	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E5E97_RS23225	ENOG4105DUX	Transporter
E5E97_RS23230	ENOG4105I93	response regulator
E5E97_RS23260	ENOG4107V40	secretion protein, HlyD family
E5E97_RS23270	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E5E97_RS23275	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
E5E97_RS23315	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E5E97_RS23365	ENOG4105C26	Dehydrogenase
E5E97_RS23375	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase