locus-tag	class	description
H7R73_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H7R73_RS00010	COG0592	DNA-directed DNA polymerase activity
H7R73_RS00020	COG0187	DNA topoisomerase II activity
H7R73_RS00025	COG2207	Transcriptional regulator
H7R73_RS00030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7R73_RS00035	COG0071	Belongs to the small heat shock protein (HSP20) family
H7R73_RS00040	COG0071	Belongs to the small heat shock protein (HSP20) family
H7R73_RS00045	COG3977	Valine--pyruvate aminotransferase
H7R73_RS00060	COG2814	Major facilitator Superfamily
H7R73_RS00065	COG0745	RESPONSE REGULATOR receiver
H7R73_RS00070	COG2205	protein histidine kinase activity
H7R73_RS00090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7R73_RS00095	COG4191	Histidine kinase
H7R73_RS00095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R73_RS00100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R73_RS00105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R73_RS00110	COG1309	transcriptional regulator
H7R73_RS00140	COG0561	phosphatase activity
H7R73_RS00145	COG2267	carboxylic ester hydrolase activity
H7R73_RS00155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7R73_RS00160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7R73_RS00165	COG1758	RNA polymerase activity
H7R73_RS00175	COG0859	PFAM glycosyl transferase family 9
H7R73_RS00180	COG3642	lipopolysaccharide core region biosynthetic process
H7R73_RS00220	COG0589	response to stress
H7R73_RS00225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H7R73_RS00230	COG3706	GGDEF domain
H7R73_RS00235	COG1528	Iron-storage protein
H7R73_RS00240	COG2081	HI0933 family
H7R73_RS00245	COG2223	nitrite transmembrane transporter activity
H7R73_RS00250	COG1280	lysine exporter protein (LysE YggA)
H7R73_RS00265	COG3188	usher protein
H7R73_RS00295	COG3275	phosphorelay sensor kinase activity
H7R73_RS00300	COG3279	Response regulator of the LytR AlgR family
H7R73_RS00305	COG2223	nitrite transmembrane transporter activity
H7R73_RS00310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7R73_RS00315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H7R73_RS00365	COG1609	Transcriptional regulator
H7R73_RS00370	COG3250	beta-galactosidase activity
H7R73_RS00375	COG2731	YhcH YjgK YiaL family protein
H7R73_RS00380	COG0531	amino acid
H7R73_RS00385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R73_RS00390	COG0531	amino acid
H7R73_RS00395	COG0385	Bile acid
H7R73_RS00400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7R73_RS00425	COG0583	DNA-binding transcription factor activity
H7R73_RS00430	COG1079	Belongs to the binding-protein-dependent transport system permease family
H7R73_RS00435	COG4603	Belongs to the binding-protein-dependent transport system permease family
H7R73_RS00440	COG3845	ABC transporter
H7R73_RS00445	COG1744	ABC transporter substrate-binding protein PnrA-like
H7R73_RS00450	COG0210	DNA helicase
H7R73_RS00460	COG3385	transposase activity
H7R73_RS00465	COG3385	transposase activity
H7R73_RS00470	COG1943	Transposase
H7R73_RS00475	COG0583	DNA-binding transcription factor activity
H7R73_RS00515	COG0583	DNA-binding transcription factor activity
H7R73_RS00530	COG1280	lysine exporter protein (LysE YggA)
H7R73_RS00540	COG2962	Rard protein
H7R73_RS00550	COG1012	belongs to the aldehyde dehydrogenase family
H7R73_RS00555	COG1396	sequence-specific DNA binding
H7R73_RS00560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7R73_RS00570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7R73_RS00570	COG0519	Catalyzes the synthesis of GMP from XMP
H7R73_RS00580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R73_RS00600	COG1322	Protein conserved in bacteria
H7R73_RS00605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7R73_RS00610	COG0569	domain protein
H7R73_RS00615	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7R73_RS00615	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7R73_RS00620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H7R73_RS00625	COG0242	peptide deformylase activity
H7R73_RS00635	COG0758	DNA mediated transformation
H7R73_RS00640	COG2922	Belongs to the Smg family
H7R73_RS00645	COG0551	DNA topoisomerase type I activity
H7R73_RS00650	COG0009	L-threonylcarbamoyladenylate synthase
H7R73_RS00655	COG0408	coproporphyrinogen oxidase activity
H7R73_RS00660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7R73_RS00665	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H7R73_RS00675	COG3078	GTPase activator activity
H7R73_RS00685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7R73_RS00690	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H7R73_RS00695	COG2204	response regulator
H7R73_RS00700	COG3852	Histidine kinase
H7R73_RS00710	COG0174	glutamine synthetase
H7R73_RS00715	COG1217	gtp-binding protein TYPA
H7R73_RS00720	COG1295	ribonuclease BN
H7R73_RS00725	COG1490	D-aminoacyl-tRNA deacylase activity
H7R73_RS00735	COG0456	acetyltransferase
H7R73_RS00745	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7R73_RS00750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7R73_RS00755	COG2610	gluconate transmembrane transporter activity
H7R73_RS00760	COG3265	gluconokinase activity
H7R73_RS00765	COG0129	dihydroxy-acid dehydratase activity
H7R73_RS00770	COG0800	Aldolase
H7R73_RS00785	COG1609	Transcriptional regulator
H7R73_RS00795	COG4942	peptidase
H7R73_RS00800	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H7R73_RS00805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7R73_RS00810	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H7R73_RS00815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H7R73_RS00820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H7R73_RS00820	COG0316	Belongs to the HesB IscA family
H7R73_RS00830	COG0596	Alpha beta hydrolase
H7R73_RS00845	COG2183	response to ionizing radiation
H7R73_RS00850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7R73_RS00860	COG2205	protein histidine kinase activity
H7R73_RS00870	COG0051	transcription antitermination factor activity, RNA binding
H7R73_RS00875	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H7R73_RS00880	COG0088	Forms part of the polypeptide exit tunnel
H7R73_RS00885	COG0089	rRNA binding
H7R73_RS00890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H7R73_RS00895	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H7R73_RS00900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H7R73_RS00905	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H7R73_RS00910	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H7R73_RS00915	COG0255	Belongs to the universal ribosomal protein uL29 family
H7R73_RS00920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H7R73_RS00925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H7R73_RS00930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H7R73_RS00935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H7R73_RS00940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7R73_RS00945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H7R73_RS00950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H7R73_RS00955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H7R73_RS00960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H7R73_RS00965	COG1841	ribosomal large subunit assembly
H7R73_RS00970	COG0200	Binds to the 23S rRNA
H7R73_RS00975	COG0201	protein transport
H7R73_RS00980	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H7R73_RS00985	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H7R73_RS00990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H7R73_RS00995	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H7R73_RS01000	COG0202	RNA polymerase activity
H7R73_RS01005	COG0203	ribosomal protein L17
H7R73_RS01065	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7R73_RS01070	COG0583	DNA-binding transcription factor activity
H7R73_RS01075	COG4221	oxidoreductase activity
H7R73_RS01090	COG1770	oligopeptidase
H7R73_RS01095	COG2358	TRAP transporter, solute receptor (TAXI family
H7R73_RS01110	COG3714	YhhN family
H7R73_RS01125	COG0583	DNA-binding transcription factor activity
H7R73_RS01155	COG2095	MarC family integral membrane protein
H7R73_RS01165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7R73_RS01175	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
H7R73_RS01185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7R73_RS01210	COG3385	transposase activity
H7R73_RS01215	COG0742	ribosomal rna small subunit methyltransferase
H7R73_RS01220	COG0552	protein localization to endoplasmic reticulum
H7R73_RS01225	COG2884	Cell division ATP-binding protein ftsE
H7R73_RS01230	COG2177	Part of the ABC transporter FtsEX involved in
H7R73_RS01240	COG0288	reversible hydration of carbon dioxide
H7R73_RS01245	COG2188	Transcriptional regulator
H7R73_RS01250	COG1228	amidohydrolase
H7R73_RS01255	COG0010	Belongs to the arginase family
H7R73_RS01260	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H7R73_RS01265	COG2986	histidine ammonia-lyase
H7R73_RS01270	COG0387	Pfam Sodium calcium exchanger
H7R73_RS01275	COG2200	EAL domain
H7R73_RS01330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7R73_RS01335	COG1459	type II secretion system
H7R73_RS01380	COG1077	Cell shape determining protein MreB Mrl
H7R73_RS01385	COG1792	Involved in formation and maintenance of cell shape
H7R73_RS01390	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H7R73_RS01395	COG0424	maF-like protein
H7R73_RS01400	COG1530	ribonuclease E activity
H7R73_RS01405	COG3164	Protein of unknown function
H7R73_RS01410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7R73_RS01415	COG0312	modulator of DNA gyrase
H7R73_RS01430	COG0477	Major facilitator Superfamily
H7R73_RS01440	COG2321	neutral zinc metallopeptidase
H7R73_RS01475	COG0189	ligase activity
H7R73_RS01480	COG0642	Histidine kinase
H7R73_RS01485	COG0745	RESPONSE REGULATOR receiver
H7R73_RS01500	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H7R73_RS01510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7R73_RS01520	COG2022	thiamine diphosphate biosynthetic process
H7R73_RS01525	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H7R73_RS01540	COG0110	maltose O-acetyltransferase activity
H7R73_RS01555	COG3932	Exopolysaccharide synthesis, ExoD
H7R73_RS01570	COG1733	regulation of RNA biosynthetic process
H7R73_RS01595	COG2226	methyltransferase
H7R73_RS01605	COG1494	fructose-1,6-bisphosphatase
H7R73_RS01615	COG3071	HemY protein
H7R73_RS01620	COG2959	enzyme of heme biosynthesis
H7R73_RS01630	COG0181	hydroxymethylbilane synthase activity
H7R73_RS01635	COG3072	Adenylate cyclase
H7R73_RS01640	COG0400	carboxylic ester hydrolase activity
H7R73_RS01645	COG1965	Belongs to the frataxin family
H7R73_RS01655	COG0019	diaminopimelate decarboxylase activity
H7R73_RS01660	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H7R73_RS01675	COG1011	Hydrolase
H7R73_RS01685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H7R73_RS01690	COG0561	phosphatase activity
H7R73_RS01700	COG1988	membrane-bound metal-dependent
H7R73_RS01705	COG1058	Belongs to the CinA family
H7R73_RS01705	COG1546	Belongs to the CinA family
H7R73_RS01715	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H7R73_RS01725	COG1522	sequence-specific DNA binding
H7R73_RS01730	COG1368	sulfuric ester hydrolase activity
H7R73_RS01745	COG1285	pathogenesis
H7R73_RS01765	COG4221	oxidoreductase activity
H7R73_RS01780	COG1979	alcohol dehydrogenase
H7R73_RS01790	COG2873	o-acetylhomoserine
H7R73_RS01820	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H7R73_RS01830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7R73_RS01835	COG2949	membrane
H7R73_RS01840	COG3291	Pkd domain containing protein
H7R73_RS01845	COG0318	PFAM AMP-dependent synthetase and ligase
H7R73_RS01855	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H7R73_RS01860	COG0596	Alpha beta hydrolase
H7R73_RS01865	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H7R73_RS01870	COG1169	isochorismate synthase
H7R73_RS01875	COG1575	Belongs to the MenA family. Type 1 subfamily
H7R73_RS01895	COG0513	Belongs to the DEAD box helicase family
H7R73_RS01900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7R73_RS01915	COG1671	Belongs to the UPF0178 family
H7R73_RS01935	COG3263	regulation of cellular component size
H7R73_RS01940	COG3722	fumarate hydratase activity
H7R73_RS01945	COG0246	Mannitol dehydrogenase
H7R73_RS01950	COG2213	PTS system mannitol-specific
H7R73_RS01950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R73_RS01955	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
H7R73_RS01965	COG3916	Acyl-homoserine-lactone synthase
H7R73_RS01970	COG2771	luxR family
H7R73_RS01985	COG1560	Kdo2-lipid A biosynthetic process
H7R73_RS01990	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H7R73_RS01990	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H7R73_RS01995	COG1538	Outer membrane efflux protein
H7R73_RS02000	COG0494	nUDIX hydrolase
H7R73_RS02005	COG3151	Protein conserved in bacteria
H7R73_RS02015	COG3150	esterase
H7R73_RS02020	COG1051	belongs to the nudix hydrolase family
H7R73_RS02035	COG1566	PFAM secretion protein HlyD family protein
H7R73_RS02040	COG1289	transmembrane transporter activity
H7R73_RS02055	COG3385	transposase activity
H7R73_RS02065	COG3385	transposase activity
H7R73_RS02125	COG0484	heat shock protein binding
H7R73_RS02135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7R73_RS02155	COG0204	Acyl-transferase
H7R73_RS02160	COG1842	Phage shock protein A
H7R73_RS02175	COG2827	Endonuclease containing a URI domain
H7R73_RS02180	COG2962	Rard protein
H7R73_RS02185	COG1573	uracil-dna glycosylase
H7R73_RS02195	COG0583	DNA-binding transcription factor activity
H7R73_RS02200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7R73_RS02205	COG1121	(ABC) transporter
H7R73_RS02210	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
H7R73_RS02230	COG0739	heme binding
H7R73_RS02240	COG3068	Protein conserved in bacteria
H7R73_RS02260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H7R73_RS02270	COG1546	Belongs to the CinA family
H7R73_RS02275	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H7R73_RS02280	COG2137	regulation of response to DNA damage stimulus
H7R73_RS02285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7R73_RS02290	COG0527	aspartate kinase activity
H7R73_RS02295	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H7R73_RS02330	COG1686	Belongs to the peptidase S11 family
H7R73_RS02335	COG0586	Pfam SNARE associated Golgi protein
H7R73_RS02340	COG1253	flavin adenine dinucleotide binding
H7R73_RS02345	COG0525	valine-tRNA ligase activity
H7R73_RS02350	COG2927	DNA polymerase III (CHI subunit)
H7R73_RS02355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H7R73_RS02360	COG0795	lipopolysaccharide-transporting ATPase activity
H7R73_RS02365	COG0795	lipopolysaccharide-transporting ATPase activity
H7R73_RS02385	COG0004	ammonium transporteR
H7R73_RS02390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7R73_RS02405	COG2165	general secretion pathway protein
H7R73_RS02410	COG0084	hydrolase, TatD family'
H7R73_RS02415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7R73_RS02425	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H7R73_RS02430	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H7R73_RS02435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H7R73_RS02445	COG4520	surface antigen
H7R73_RS02450	COG3447	MASE1 domain protein
H7R73_RS02450	COG5002	protein histidine kinase activity
H7R73_RS02450	COG5001	Diguanylate cyclase
H7R73_RS02460	COG0560	Phosphoserine phosphatase
H7R73_RS02475	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H7R73_RS02485	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
H7R73_RS02490	COG0776	regulation of translation
H7R73_RS02500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7R73_RS02505	COG0735	belongs to the Fur family
H7R73_RS02525	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H7R73_RS02530	COG0513	Belongs to the DEAD box helicase family
H7R73_RS02535	COG3022	response to hydroperoxide
H7R73_RS02550	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H7R73_RS02555	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7R73_RS02560	COG0762	integral membrane protein
H7R73_RS02565	COG1872	DUF167
H7R73_RS02585	COG3112	Uncharacterised protein family (UPF0231)
H7R73_RS02590	COG3835	regulator
H7R73_RS02595	COG2610	gluconate transmembrane transporter activity
H7R73_RS02600	COG1929	Belongs to the glycerate kinase type-1 family
H7R73_RS02615	COG0583	DNA-binding transcription factor activity
H7R73_RS02620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7R73_RS02635	COG0347	Belongs to the P(II) protein family
H7R73_RS02650	COG3842	ATPase activity
H7R73_RS02655	COG2837	iron assimilation
H7R73_RS02660	COG1438	arginine binding
H7R73_RS02665	COG1126	abc transporter atp-binding protein
H7R73_RS02670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R73_RS02675	COG4215	(ABC) transporter
H7R73_RS02680	COG4160	amino acid transport
H7R73_RS02685	COG0039	L-malate dehydrogenase activity
H7R73_RS02690	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H7R73_RS02695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R73_RS02695	COG1017	nitric oxide dioxygenase activity
H7R73_RS02705	COG4536	flavin adenine dinucleotide binding
H7R73_RS02710	COG4137	Cytochrome C assembly protein
H7R73_RS02715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7R73_RS02720	COG0228	four-way junction DNA binding
H7R73_RS02725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7R73_RS02730	COG0336	Belongs to the RNA methyltransferase TrmD family
H7R73_RS02735	COG0335	large ribosomal subunit rRNA binding
H7R73_RS02745	COG3066	DNA modification
H7R73_RS02750	COG1051	belongs to the nudix hydrolase family
H7R73_RS02760	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H7R73_RS02765	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H7R73_RS02770	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H7R73_RS02780	COG0583	DNA-binding transcription factor activity
H7R73_RS02785	COG0640	Transcriptional regulator
H7R73_RS02790	COG0268	Binds directly to 16S ribosomal RNA
H7R73_RS02795	COG0728	peptidoglycan biosynthetic process
H7R73_RS02800	COG0196	riboflavin kinase activity
H7R73_RS02805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H7R73_RS02810	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H7R73_RS02815	COG1047	Peptidyl-prolyl cis-trans
H7R73_RS02820	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H7R73_RS02860	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7R73_RS02860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7R73_RS02875	COG1854	S-ribosylhomocysteine lyase activity
H7R73_RS02880	COG3706	GGDEF domain
H7R73_RS02885	COG0557	exoribonuclease II activity
H7R73_RS02890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7R73_RS02900	COG2153	protein acetylation
H7R73_RS02910	COG1914	H( )-stimulated, divalent metal cation uptake system
H7R73_RS02915	COG0360	Binds together with S18 to 16S ribosomal RNA
H7R73_RS02920	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H7R73_RS02925	COG0359	binds to the 23S rRNA
H7R73_RS02965	COG1238	metal cluster binding
H7R73_RS02970	COG0612	Peptidase, M16
H7R73_RS02975	COG2918	glutathione biosynthetic process
H7R73_RS02980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H7R73_RS02985	COG1027	Aspartate ammonia-lyase
H7R73_RS02990	COG3030	protein affecting phage T7 exclusion by the F plasmid
H7R73_RS02995	COG0534	Mate efflux family protein
H7R73_RS03000	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H7R73_RS03005	COG0459	protein refolding
H7R73_RS03025	COG0564	pseudouridine synthase activity
H7R73_RS03030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7R73_RS03065	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H7R73_RS03075	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H7R73_RS03080	COG4208	sulfate ABC transporter
H7R73_RS03085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H7R73_RS03090	COG0583	DNA-binding transcription factor activity
H7R73_RS03095	COG3397	chitin binding
H7R73_RS03100	COG0840	transmembrane signaling receptor activity
H7R73_RS03125	COG1328	CTP reductase activity
H7R73_RS03130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H7R73_RS03145	COG1448	Aminotransferase
H7R73_RS03150	COG2194	sulfuric ester hydrolase activity
H7R73_RS03170	COG1215	transferase activity, transferring glycosyl groups
H7R73_RS03180	COG0457	Tetratricopeptide repeat
H7R73_RS03180	COG3118	belongs to the thioredoxin family
H7R73_RS03215	COG0513	Belongs to the DEAD box helicase family
H7R73_RS03220	COG0840	transmembrane signaling receptor activity
H7R73_RS03230	COG4166	transmembrane transport
H7R73_RS03245	COG1024	Enoyl-CoA hydratase
H7R73_RS03260	COG4221	oxidoreductase activity
H7R73_RS03265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R73_RS03270	COG0442	prolyl-tRNA aminoacylation
H7R73_RS03275	COG0840	transmembrane signaling receptor activity
H7R73_RS03280	COG0632	four-way junction helicase activity
H7R73_RS03285	COG2255	four-way junction helicase activity
H7R73_RS03295	COG1271	oxidase subunit
H7R73_RS03300	COG1294	oxidase, subunit
H7R73_RS03305	COG4890	Cyd operon protein YbgT
H7R73_RS03310	COG3790	cyd operon protein YbgE
H7R73_RS03315	COG0824	Thioesterase
H7R73_RS03320	COG0811	peptide transport
H7R73_RS03335	COG0823	Involved in the tonB-independent uptake of proteins
H7R73_RS03340	COG2885	chlorophyll binding
H7R73_RS03345	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
H7R73_RS03420	COG0840	transmembrane signaling receptor activity
H7R73_RS03425	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H7R73_RS03435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7R73_RS03440	COG1640	4-alpha-glucanotransferase
H7R73_RS03445	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H7R73_RS03470	COG1051	belongs to the nudix hydrolase family
H7R73_RS03475	COG2130	NADP-dependent
H7R73_RS03480	COG1846	Transcriptional regulator
H7R73_RS03510	COG0561	phosphatase activity
H7R73_RS03525	COG0733	neurotransmitter:sodium symporter activity
H7R73_RS03530	COG0733	neurotransmitter:sodium symporter activity
H7R73_RS03545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R73_RS03560	COG1794	racemase activity, acting on amino acids and derivatives
H7R73_RS03570	COG1022	Amp-dependent synthetase and ligase
H7R73_RS03580	COG0456	acetyltransferase
H7R73_RS03595	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H7R73_RS03600	COG5002	protein histidine kinase activity
H7R73_RS03600	COG5001	Diguanylate cyclase
H7R73_RS03620	COG0456	acetyltransferase
H7R73_RS03630	COG0456	acetyltransferase
H7R73_RS03635	COG1902	pentaerythritol trinitrate reductase activity
H7R73_RS03650	COG2957	Belongs to the agmatine deiminase family
H7R73_RS03655	COG0154	amidase activity
H7R73_RS03660	COG2801	Transposase and inactivated derivatives
H7R73_RS03705	COG1917	Cupin 2, conserved barrel domain protein
H7R73_RS03705	COG2207	Transcriptional regulator
H7R73_RS03715	COG0513	Belongs to the DEAD box helicase family
H7R73_RS03725	COG2199	diguanylate cyclase activity
H7R73_RS03725	COG2203	Gaf domain
H7R73_RS03760	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
H7R73_RS03770	COG1136	(ABC) transporter
H7R73_RS03770	COG0577	efflux transmembrane transporter activity
H7R73_RS03775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R73_RS03780	COG0745	RESPONSE REGULATOR receiver
H7R73_RS03785	COG2205	protein histidine kinase activity
H7R73_RS03840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7R73_RS03850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H7R73_RS03860	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
H7R73_RS03865	COG1178	ABC-type Fe3 transport system permease component
H7R73_RS03870	COG4143	(ABC) transporter
H7R73_RS03885	COG0066	3-isopropylmalate dehydratase activity
H7R73_RS03890	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H7R73_RS03895	COG0473	3-isopropylmalate dehydrogenase activity
H7R73_RS03900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7R73_RS03910	COG0671	phosphoesterase, PA-phosphatase related
H7R73_RS03925	COG0028	Belongs to the TPP enzyme family
H7R73_RS03930	COG0440	acetolactate synthase activity
H7R73_RS03935	COG0857	belongs to the CobB CobQ family
H7R73_RS03935	COG0280	phosphate acetyltransferase
H7R73_RS03940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7R73_RS03950	COG3013	Belongs to the UPF0304 family
H7R73_RS03955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7R73_RS03960	COG2716	regulation of RNA biosynthetic process
H7R73_RS03965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7R73_RS03970	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H7R73_RS03975	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H7R73_RS03990	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H7R73_RS04010	COG5002	protein histidine kinase activity
H7R73_RS04010	COG0784	Response regulator, receiver
H7R73_RS04010	COG2198	Histidine kinase
H7R73_RS04015	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H7R73_RS04025	COG2205	protein histidine kinase activity
H7R73_RS04025	COG0784	Response regulator, receiver
H7R73_RS04045	COG1464	Belongs to the NlpA lipoprotein family
H7R73_RS04050	COG2011	ABC-type metal ion transport system permease component
H7R73_RS04055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7R73_RS04075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H7R73_RS04075	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H7R73_RS04080	COG0802	atpase or kinase
H7R73_RS04090	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7R73_RS04095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H7R73_RS04100	COG1923	regulation of RNA biosynthetic process
H7R73_RS04105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7R73_RS04110	COG0330	HflC and HflK could
H7R73_RS04115	COG0330	HflC and HflK could
H7R73_RS04120	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H7R73_RS04125	COG0142	geranyltranstransferase activity
H7R73_RS04130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H7R73_RS04135	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H7R73_RS04140	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H7R73_RS04145	COG3314	Sporulation integral membrane protein YlbJ
H7R73_RS04150	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H7R73_RS04155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R73_RS04165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7R73_RS04170	COG2967	ApaG domain
H7R73_RS04175	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7R73_RS04180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H7R73_RS04190	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H7R73_RS04195	COG3178	'Phosphotransferase
H7R73_RS04200	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H7R73_RS04205	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H7R73_RS04210	COG2252	PERMEase
H7R73_RS04220	COG0488	(ABC) transporter
H7R73_RS04225	COG0582	viral genome integration into host DNA
H7R73_RS04240	COG0629	single-stranded DNA binding
H7R73_RS04400	COG1802	Transcriptional regulator
H7R73_RS04400	COG4626	Terminase
H7R73_RS04415	COG0616	signal peptide processing
H7R73_RS04455	COG4386	tail sheath protein
H7R73_RS04475	COG2314	TM2 domain
H7R73_RS04500	COG3299	homolog of phage Mu protein gp47
H7R73_RS04505	COG3778	Protein conserved in bacteria
H7R73_RS04545	COG0741	lytic transglycosylase activity
H7R73_RS04550	COG0463	Glycosyl transferase, family 2
H7R73_RS04560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H7R73_RS04585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R73_RS04595	COG3721	Heme iron utilization protein
H7R73_RS04600	COG0748	coenzyme F420 binding
H7R73_RS04625	COG2814	Major facilitator Superfamily
H7R73_RS04630	COG2205	protein histidine kinase activity
H7R73_RS04630	COG2202	Pas domain
H7R73_RS04640	COG2226	methyltransferase
H7R73_RS04650	COG1765	OsmC-like protein
H7R73_RS04665	COG3954	Phosphoribulokinase
H7R73_RS04670	COG3089	Belongs to the UPF0270 family
H7R73_RS04675	COG4251	negative regulation of phosphorylation
H7R73_RS04675	COG3706	GGDEF domain
H7R73_RS04675	COG2203	Gaf domain
H7R73_RS04675	COG5001	Diguanylate cyclase
H7R73_RS04680	COG0429	hydrolase of the alpha beta-hydrolase fold
H7R73_RS04685	COG0784	Response regulator, receiver
H7R73_RS04685	COG0835	chemotaxis
H7R73_RS04695	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H7R73_RS04700	COG1047	Peptidyl-prolyl cis-trans
H7R73_RS04705	COG2900	Belongs to the SlyX family
H7R73_RS04715	COG0545	Peptidyl-prolyl cis-trans isomerase
H7R73_RS04720	COG2204	response regulator
H7R73_RS04770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7R73_RS04775	COG0506	proline dehydrogenase activity
H7R73_RS04775	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7R73_RS04775	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7R73_RS04785	COG0114	fumarate hydratase activity
H7R73_RS04795	COG1566	PFAM secretion protein HlyD family protein
H7R73_RS04865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7R73_RS04875	COG1280	lysine exporter protein (LysE YggA)
H7R73_RS04880	COG0826	peptidase U32
H7R73_RS04890	COG3813	Protein conserved in bacteria
H7R73_RS04970	COG0300	oxidoreductase activity
H7R73_RS04990	COG2610	gluconate transmembrane transporter activity
H7R73_RS04995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7R73_RS05000	COG3622	Belongs to the hyi family
H7R73_RS05005	COG0235	Class ii aldolase
H7R73_RS05010	COG3395	kinase activity
H7R73_RS05015	COG2084	Dehydrogenase
H7R73_RS05020	COG1349	DNA-binding transcription factor activity
H7R73_RS05030	COG2133	pyrroloquinoline quinone binding
H7R73_RS05055	COG3385	transposase activity
H7R73_RS05075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7R73_RS05100	COG3039	Transposase
H7R73_RS05115	COG3385	transposase activity
H7R73_RS05130	COG3385	transposase activity
H7R73_RS05145	COG2003	Belongs to the UPF0758 family
H7R73_RS05190	COG5377	YqaJ viral recombinase family
H7R73_RS05220	COG1605	Chorismate mutase
H7R73_RS05220	COG0077	Prephenate dehydratase
H7R73_RS05245	COG3272	Protein of unknown function (DUF1722)
H7R73_RS05250	COG0789	Transcriptional regulator
H7R73_RS05255	COG0415	Belongs to the DNA photolyase family
H7R73_RS05265	COG4221	oxidoreductase activity
H7R73_RS05280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7R73_RS05305	COG0783	Belongs to the Dps family
H7R73_RS05310	COG1151	hydroxylamine reductase activity
H7R73_RS05320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7R73_RS05340	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7R73_RS05345	COG2723	6-phospho-beta-galactosidase activity
H7R73_RS05350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R73_RS05350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R73_RS05355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R73_RS05360	COG2273	Hydrolase Family 16
H7R73_RS05360	COG5297	Belongs to the glycosyl hydrolase family 6
H7R73_RS05365	COG1472	Belongs to the glycosyl hydrolase 3 family
H7R73_RS05370	COG0840	transmembrane signaling receptor activity
H7R73_RS05375	COG2182	Extracellular solute-binding protein
H7R73_RS05380	COG1609	Transcriptional regulator
H7R73_RS05405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R73_RS05410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R73_RS05415	COG0745	RESPONSE REGULATOR receiver
H7R73_RS05420	COG5000	phosphorelay sensor kinase activity
H7R73_RS05420	COG5002	protein histidine kinase activity
H7R73_RS05425	COG0659	secondary active sulfate transmembrane transporter activity
H7R73_RS05430	COG2771	luxR family
H7R73_RS05450	COG4104	PAAR repeat-containing protein
H7R73_RS05460	COG3385	transposase activity
H7R73_RS05520	COG3385	transposase activity
H7R73_RS05530	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7R73_RS05535	COG1666	GTP binding
H7R73_RS05545	COG2211	Major facilitator Superfamily
H7R73_RS05555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7R73_RS05565	COG2813	Specifically methylates the guanine in position
H7R73_RS05570	COG0271	Belongs to the BolA IbaG family
H7R73_RS05575	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H7R73_RS05580	COG1805	sodium ion transport
H7R73_RS05585	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H7R73_RS05590	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H7R73_RS05595	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H7R73_RS05600	COG2871	sodium ion transport
H7R73_RS05605	COG1477	protein flavinylation
H7R73_RS05620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7R73_RS05625	COG0840	transmembrane signaling receptor activity
H7R73_RS05630	COG0583	DNA-binding transcription factor activity
H7R73_RS05645	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
H7R73_RS05655	COG0473	3-isopropylmalate dehydrogenase activity
H7R73_RS05660	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7R73_RS05665	COG1611	Belongs to the LOG family
H7R73_RS05680	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H7R73_RS05680	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H7R73_RS05690	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
H7R73_RS05715	COG3098	single-species biofilm formation
H7R73_RS05720	COG0564	pseudouridine synthase activity
H7R73_RS05735	COG4580	involved in the transport of maltose and maltodextrins
H7R73_RS05750	COG1263	PTS System
H7R73_RS05750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R73_RS05760	COG2171	N-acyltransferase activity
H7R73_RS05765	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
H7R73_RS05770	COG0024	Methionine aminopeptidase
H7R73_RS05775	COG0052	Belongs to the universal ribosomal protein uS2 family
H7R73_RS05780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H7R73_RS05785	COG0528	UMP kinase activity
H7R73_RS05790	COG0233	cytoplasmic translational termination
H7R73_RS05795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7R73_RS05800	COG0575	Belongs to the CDS family
H7R73_RS05805	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H7R73_RS05810	COG0750	zinc metalloprotease
H7R73_RS05825	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7R73_RS05830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7R73_RS05835	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7R73_RS05840	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7R73_RS05845	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7R73_RS05855	COG0825	malonyl-CoA metabolic process
H7R73_RS05870	COG0814	amino acid
H7R73_RS05875	COG0531	amino acid
H7R73_RS05885	COG0488	(ABC) transporter
H7R73_RS05895	COG3590	peptidase
H7R73_RS05900	COG0037	tRNA processing
H7R73_RS05905	COG3706	GGDEF domain
H7R73_RS05940	COG0366	Alpha amylase catalytic
H7R73_RS05955	COG0463	Glycosyl transferase, family 2
H7R73_RS05970	COG3385	transposase activity
H7R73_RS05980	COG2989	Protein conserved in bacteria
H7R73_RS05985	COG3108	Peptidase M15
H7R73_RS05995	COG2860	membrane
H7R73_RS06005	COG1196	nuclear chromosome segregation
H7R73_RS06010	COG3115	cell septum assembly
H7R73_RS06015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H7R73_RS06025	COG1328	CTP reductase activity
H7R73_RS06030	COG0602	queuosine metabolic process
H7R73_RS06055	COG1566	PFAM secretion protein HlyD family protein
H7R73_RS06065	COG3290	protein histidine kinase activity
H7R73_RS06080	COG0667	Aldo Keto reductase
H7R73_RS06085	COG0697	spore germination
H7R73_RS06100	COG3284	Transcriptional regulator
H7R73_RS06105	COG3706	GGDEF domain
H7R73_RS06110	COG0346	lactoylglutathione lyase activity
H7R73_RS06115	COG0745	RESPONSE REGULATOR receiver
H7R73_RS06120	COG5002	protein histidine kinase activity
H7R73_RS06130	COG4783	chaperone-mediated protein folding
H7R73_RS06140	COG1940	carbohydrate kinase activity
H7R73_RS06145	COG3142	Participates in the control of copper homeostasis
H7R73_RS06155	COG0545	Peptidyl-prolyl cis-trans isomerase
H7R73_RS06175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R73_RS06180	COG4597	amino acid ABC transporter
H7R73_RS06185	COG0765	amino acid transport
H7R73_RS06190	COG1126	abc transporter atp-binding protein
H7R73_RS06200	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H7R73_RS06205	COG0678	peroxiredoxin activity
H7R73_RS06215	COG0019	diaminopimelate decarboxylase activity
H7R73_RS06220	COG1115	amino acid carrier protein
H7R73_RS06225	COG0095	Lipoate-protein ligase
H7R73_RS06230	COG2233	PERMEase
H7R73_RS06245	COG0534	Mate efflux family protein
H7R73_RS06250	COG2207	Transcriptional regulator
H7R73_RS06255	COG0281	malic enzyme
H7R73_RS06270	COG3385	transposase activity
H7R73_RS06290	COG0733	neurotransmitter:sodium symporter activity
H7R73_RS06295	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7R73_RS06300	COG3706	GGDEF domain
H7R73_RS06310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R73_RS06380	COG0673	inositol 2-dehydrogenase activity
H7R73_RS06385	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H7R73_RS06390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H7R73_RS06395	COG0741	lytic transglycosylase activity
H7R73_RS06395	COG0739	heme binding
H7R73_RS06395	COG1196	nuclear chromosome segregation
H7R73_RS06420	COG0788	formyltetrahydrofolate deformylase activity
H7R73_RS06425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7R73_RS06435	COG3118	belongs to the thioredoxin family
H7R73_RS06445	COG0791	NLP P60 protein
H7R73_RS06450	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
H7R73_RS06465	COG1388	LysM domain
H7R73_RS06465	COG1376	ErfK ybiS ycfS ynhG family protein
H7R73_RS06475	COG2205	protein histidine kinase activity
H7R73_RS06475	COG0784	Response regulator, receiver
H7R73_RS06500	COG2205	protein histidine kinase activity
H7R73_RS06500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R73_RS06505	COG3384	dioxygenase
H7R73_RS06515	COG1283	sodium-dependent phosphate transmembrane transporter activity
H7R73_RS06525	COG0531	amino acid
H7R73_RS06530	COG0531	amino acid
H7R73_RS06545	COG1012	belongs to the aldehyde dehydrogenase family
H7R73_RS06550	COG1917	Cupin 2, conserved barrel domain protein
H7R73_RS06550	COG1396	sequence-specific DNA binding
H7R73_RS06555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7R73_RS06590	COG4651	solute:proton antiporter activity
H7R73_RS06590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7R73_RS06595	COG0405	Gamma-glutamyltransferase
H7R73_RS06605	COG2974	May be involved in recombination
H7R73_RS06610	COG1247	-acetyltransferase
H7R73_RS06615	COG0420	3'-5' exonuclease activity
H7R73_RS06625	COG3038	cytochrome b561
H7R73_RS06630	COG2190	(PTS) system
H7R73_RS06640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R73_RS06645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7R73_RS06650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7R73_RS06665	COG1720	tRNA m6t6A37 methyltransferase activity
H7R73_RS06685	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H7R73_RS06690	COG4988	ABC transporter
H7R73_RS06705	COG0745	RESPONSE REGULATOR receiver
H7R73_RS06715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7R73_RS06730	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
H7R73_RS06735	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
H7R73_RS06745	COG0083	homoserine kinase activity
H7R73_RS06750	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7R73_RS06765	COG2801	Transposase and inactivated derivatives
H7R73_RS06780	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H7R73_RS06805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7R73_RS06815	COG3220	belongs to the UPF0276 family
H7R73_RS06845	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H7R73_RS06850	COG1289	transmembrane transporter activity
H7R73_RS06855	COG1763	Mo-molybdopterin cofactor biosynthetic process
H7R73_RS06860	COG0746	molybdenum cofactor guanylyltransferase activity
H7R73_RS06865	COG0281	malic enzyme
H7R73_RS06875	COG3385	transposase activity
H7R73_RS06880	COG4584	PFAM Integrase catalytic
H7R73_RS06885	COG1484	DNA-dependent DNA replication
H7R73_RS06905	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H7R73_RS06975	COG3385	transposase activity
H7R73_RS06990	COG2003	Belongs to the UPF0758 family
H7R73_RS07035	COG5377	YqaJ viral recombinase family
H7R73_RS07075	COG1091	dTDP-4-dehydrorhamnose reductase activity
H7R73_RS07110	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H7R73_RS07130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7R73_RS07205	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H7R73_RS07215	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H7R73_RS07230	COG0443	Heat shock 70 kDa protein
H7R73_RS07235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7R73_RS07265	COG0582	viral genome integration into host DNA
H7R73_RS07270	COG0012	GTP binding
H7R73_RS07275	COG0193	aminoacyl-tRNA hydrolase activity
H7R73_RS07280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7R73_RS07290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H7R73_RS07295	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H7R73_RS07300	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H7R73_RS07305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H7R73_RS07310	COG2890	protein-(glutamine-N5) methyltransferase activity
H7R73_RS07320	COG2912	Transglutaminase-like superfamily
H7R73_RS07325	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H7R73_RS07330	COG3385	transposase activity
H7R73_RS07355	COG1196	nuclear chromosome segregation
H7R73_RS07355	COG3264	Mechanosensitive ion channel
H7R73_RS07365	COG2850	peptidyl-arginine hydroxylation
H7R73_RS07370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7R73_RS07375	COG2915	High frequency lysogenization protein hflD homolog
H7R73_RS07380	COG0482	sulfurtransferase activity
H7R73_RS07390	COG1187	pseudouridine synthase activity
H7R73_RS07395	COG0456	acetyltransferase
H7R73_RS07430	COG0538	isocitrate dehydrogenase activity
H7R73_RS07440	COG3048	D-serine ammonia-lyase activity
H7R73_RS07445	COG0583	DNA-binding transcription factor activity
H7R73_RS07450	COG2916	Histone family protein nucleoid-structuring protein H-NS
H7R73_RS07455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7R73_RS07460	COG2375	cellular response to nickel ion
H7R73_RS07470	COG0577	efflux transmembrane transporter activity
H7R73_RS07470	COG1136	(ABC) transporter
H7R73_RS07475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R73_RS07485	COG0497	DNA recombination
H7R73_RS07490	COG3706	GGDEF domain
H7R73_RS07495	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7R73_RS07500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H7R73_RS07505	COG0443	Heat shock 70 kDa protein
H7R73_RS07510	COG0484	heat shock protein binding
H7R73_RS07540	COG1285	pathogenesis
H7R73_RS07550	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R73_RS07570	COG2391	methyltransferase activity
H7R73_RS07590	COG0095	Lipoate-protein ligase
H7R73_RS07605	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R73_RS07610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R73_RS07620	COG0708	Exodeoxyribonuclease III
H7R73_RS07630	COG0745	RESPONSE REGULATOR receiver
H7R73_RS07645	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
H7R73_RS07660	COG1846	Transcriptional regulator
H7R73_RS07680	COG0583	DNA-binding transcription factor activity
H7R73_RS07685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7R73_RS07690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7R73_RS07695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7R73_RS07700	COG1845	cytochrome c oxidase, subunit III
H7R73_RS07705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7R73_RS07710	COG0109	protoheme IX farnesyltransferase activity
H7R73_RS07720	COG2814	Major facilitator Superfamily
H7R73_RS07725	COG5507	3-demethylubiquinone-9 3-methyltransferase
H7R73_RS07730	COG2175	clavaminate synthase activity
H7R73_RS07735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R73_RS07740	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H7R73_RS07745	COG4521	taurine ABC transporter
H7R73_RS07845	COG3385	transposase activity
H7R73_RS07855	COG0159	tryptophan synthase activity
H7R73_RS07860	COG0133	tryptophan synthase activity
H7R73_RS07865	COG0134	indole-3-glycerol-phosphate synthase activity
H7R73_RS07865	COG0135	phosphoribosylanthranilate isomerase activity
H7R73_RS07870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7R73_RS07875	COG0512	Glutamine amidotransferase of anthranilate synthase
H7R73_RS07875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7R73_RS07880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7R73_RS07885	COG0613	PHP domain protein
H7R73_RS07890	COG0009	L-threonylcarbamoyladenylate synthase
H7R73_RS07900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7R73_RS07915	COG1946	Acyl-CoA thioesterase
H7R73_RS07930	COG1309	transcriptional regulator
H7R73_RS07935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R73_RS07940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R73_RS07970	COG3385	transposase activity
H7R73_RS08015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H7R73_RS08020	COG3385	transposase activity
H7R73_RS08030	COG1960	acyl-CoA dehydrogenase activity
H7R73_RS08035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R73_RS08045	COG0469	pyruvate kinase activity
H7R73_RS08050	COG1737	Transcriptional regulator
H7R73_RS08055	COG0837	glucose binding
H7R73_RS08075	COG1091	dTDP-4-dehydrorhamnose reductase activity
H7R73_RS08085	COG3385	transposase activity
H7R73_RS08110	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H7R73_RS08135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7R73_RS08165	COG3132	Protein of unknown function, DUF480
H7R73_RS08190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7R73_RS08205	COG1278	Cold shock
H7R73_RS08230	COG4166	transmembrane transport
H7R73_RS08235	COG0697	spore germination
H7R73_RS08245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H7R73_RS08260	COG4166	transmembrane transport
H7R73_RS08265	COG0622	Phosphoesterase
H7R73_RS08280	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
H7R73_RS08290	COG0784	Response regulator, receiver
H7R73_RS08290	COG0835	chemotaxis
H7R73_RS08295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H7R73_RS08300	COG1815	bacterial-type flagellum-dependent cell motility
H7R73_RS08315	COG1749	Flagellar hook protein flgE
H7R73_RS08330	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H7R73_RS08335	COG1706	bacterial-type flagellum-dependent cell motility
H7R73_RS08340	COG3951	Flagellar rod assembly protein muramidase FlgJ
H7R73_RS08340	COG1705	Flagellar rod assembly protein muramidase FlgJ
H7R73_RS08355	COG2239	Acts as a magnesium transporter
H7R73_RS08365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H7R73_RS08370	COG2716	regulation of RNA biosynthetic process
H7R73_RS08395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7R73_RS08400	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7R73_RS08405	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H7R73_RS08410	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H7R73_RS08435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H7R73_RS08450	COG0590	tRNA wobble adenosine to inosine editing
H7R73_RS08455	COG0573	inorganic phosphate transmembrane transporter activity
H7R73_RS08460	COG0581	inorganic phosphate transmembrane transporter activity
H7R73_RS08465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7R73_RS08470	COG0704	Plays a role in the regulation of phosphate uptake
H7R73_RS08475	COG1253	flavin adenine dinucleotide binding
H7R73_RS08490	COG0531	amino acid
H7R73_RS08505	COG1126	abc transporter atp-binding protein
H7R73_RS08510	COG0765	amino acid transport
H7R73_RS08515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R73_RS08520	COG3706	GGDEF domain
H7R73_RS08525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7R73_RS08545	COG3385	transposase activity
H7R73_RS08555	COG1785	Belongs to the alkaline phosphatase family
H7R73_RS08560	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7R73_RS08565	COG0477	Major facilitator Superfamily
H7R73_RS08570	COG0123	including yeast histone deacetylase and acetoin utilization protein
H7R73_RS08580	COG1199	ATP-dependent helicase activity
H7R73_RS08610	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H7R73_RS08625	COG1448	Aminotransferase
H7R73_RS08630	COG0433	COG0433 Predicted ATPase
H7R73_RS08645	COG0658	competence protein
H7R73_RS08645	COG2333	competence protein COMEC
H7R73_RS08650	COG1132	(ABC) transporter
H7R73_RS08655	COG1663	tetraacyldisaccharide 4'-kinase activity
H7R73_RS08660	COG2835	tetraacyldisaccharide 4'-kinase activity
H7R73_RS08665	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H7R73_RS08670	COG2197	response regulator
H7R73_RS08675	COG0322	excinuclease ABC activity
H7R73_RS08750	COG0582	viral genome integration into host DNA
H7R73_RS08760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7R73_RS08765	COG1061	Type III restriction enzyme res subunit
H7R73_RS08770	COG1002	Type II restriction enzyme, methylase subunits
H7R73_RS08780	COG3385	transposase activity
H7R73_RS08790	COG0604	alcohol dehydrogenase
H7R73_RS08795	COG1309	transcriptional regulator
H7R73_RS08800	COG2261	transglycosylase associated protein
H7R73_RS08805	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7R73_RS08815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7R73_RS08825	COG2801	Transposase and inactivated derivatives
H7R73_RS08860	COG3385	transposase activity
H7R73_RS08865	COG0840	transmembrane signaling receptor activity
H7R73_RS08885	COG0741	lytic transglycosylase activity
H7R73_RS08905	COG4962	Type ii secretion system protein e
H7R73_RS08920	COG3451	type IV secretory pathway VirB4
H7R73_RS08935	COG3846	protein secretion by the type IV secretion system
H7R73_RS08950	COG2948	multi-organism process
H7R73_RS08960	COG0583	DNA-binding transcription factor activity
H7R73_RS08965	COG1846	Transcriptional regulator
H7R73_RS08995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7R73_RS09015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7R73_RS09025	COG0583	DNA-binding transcription factor activity
H7R73_RS09035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7R73_RS09040	COG0625	glutathione transferase activity
H7R73_RS09085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H7R73_RS09130	COG3385	transposase activity
H7R73_RS09140	COG2199	diguanylate cyclase activity
H7R73_RS09140	COG2203	Gaf domain
H7R73_RS09175	COG2119	membrane
H7R73_RS09180	COG0023	Translation Initiation Factor
H7R73_RS09190	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H7R73_RS09215	COG4139	cobalamin transport
H7R73_RS09220	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
H7R73_RS09225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7R73_RS09230	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H7R73_RS09235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7R73_RS09240	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H7R73_RS09245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7R73_RS09255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H7R73_RS09260	COG0505	Belongs to the CarA family
H7R73_RS09265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7R73_RS09270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7R73_RS09275	COG3706	GGDEF domain
H7R73_RS09305	COG0513	Belongs to the DEAD box helicase family
H7R73_RS09315	COG4104	PAAR repeat-containing protein
H7R73_RS09335	COG0493	'glutamate synthase
H7R73_RS09340	COG0070	glutamate synthase
H7R73_RS09340	COG0069	glutamate synthase activity
H7R73_RS09340	COG0067	glutamate synthase
H7R73_RS09345	COG1242	4 iron, 4 sulfur cluster binding
H7R73_RS09390	COG1113	amino acid transport
H7R73_RS09400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H7R73_RS09405	COG0574	Belongs to the PEP-utilizing enzyme family
H7R73_RS09405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7R73_RS09420	COG1119	ATPase activity
H7R73_RS09440	COG1464	Belongs to the NlpA lipoprotein family
H7R73_RS09450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7R73_RS09455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7R73_RS09465	COG0101	tRNA pseudouridine synthase activity
H7R73_RS09470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H7R73_RS09475	COG0285	dihydrofolate synthase activity
H7R73_RS09480	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
H7R73_RS09485	COG2920	part of a sulfur-relay system
H7R73_RS09490	COG1289	transmembrane transporter activity
H7R73_RS09495	COG0670	Belongs to the BI1 family
H7R73_RS09535	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H7R73_RS09545	COG2175	clavaminate synthase activity
H7R73_RS09550	COG3246	L-lysine catabolic process to acetate
H7R73_RS09555	COG2814	Major facilitator Superfamily
H7R73_RS09565	COG2855	membrane
H7R73_RS09610	COG0318	PFAM AMP-dependent synthetase and ligase
H7R73_RS09620	COG5001	Diguanylate cyclase
H7R73_RS09625	COG0564	pseudouridine synthase activity
H7R73_RS09640	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
H7R73_RS09650	COG0625	glutathione transferase activity
H7R73_RS09665	COG0367	asparagine synthase
H7R73_RS09675	COG0647	UMP catabolic process
H7R73_RS09680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H7R73_RS09690	COG1902	pentaerythritol trinitrate reductase activity
H7R73_RS09695	COG1253	flavin adenine dinucleotide binding
H7R73_RS09705	COG0247	lactate metabolic process
H7R73_RS09705	COG0277	FAD linked oxidase domain protein
H7R73_RS09715	COG2050	protein possibly involved in aromatic compounds catabolism
H7R73_RS09730	COG5001	Diguanylate cyclase
H7R73_RS09735	COG0583	DNA-binding transcription factor activity
H7R73_RS09740	COG2814	Major facilitator Superfamily
H7R73_RS09745	COG2056	Na+-H+ antiporter family
H7R73_RS09750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R73_RS09765	COG0483	inositol monophosphate 1-phosphatase activity
H7R73_RS09775	COG0625	glutathione transferase activity
H7R73_RS09780	COG0625	glutathione transferase activity
H7R73_RS09790	COG0601	transmembrane transport
H7R73_RS09795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R73_RS09805	COG2814	Major facilitator Superfamily
H7R73_RS09825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R73_RS09830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R73_RS09835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H7R73_RS09840	COG0509	glycine decarboxylation via glycine cleavage system
H7R73_RS09845	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7R73_RS09845	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7R73_RS09875	COG3634	alkyl hydroperoxide reductase activity
H7R73_RS09880	COG0450	alkyl hydroperoxide reductase
H7R73_RS09885	COG0517	IMP dehydrogenase activity
H7R73_RS09890	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H7R73_RS09895	COG0343	queuine tRNA-ribosyltransferase activity
H7R73_RS09900	COG1862	Preprotein translocase
H7R73_RS09905	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7R73_RS09910	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7R73_RS09915	COG2897	thiosulfate sulfurtransferase activity
H7R73_RS09925	COG0826	peptidase U32
H7R73_RS09930	COG0826	peptidase U32
H7R73_RS09935	COG3154	lipid carrier protein
H7R73_RS09950	COG1104	cysteine desulfurase activity
H7R73_RS09955	COG0822	iron-sulfur transferase activity
H7R73_RS09965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H7R73_RS09970	COG0443	Heat shock 70 kDa protein
H7R73_RS09975	COG0633	Ferredoxin
H7R73_RS09985	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H7R73_RS09990	COG0105	UTP biosynthetic process
H7R73_RS09995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H7R73_RS10005	COG1426	Protein conserved in bacteria
H7R73_RS10010	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H7R73_RS10015	COG0124	histidyl-tRNA synthetase
H7R73_RS10020	COG2976	Protein conserved in bacteria
H7R73_RS10025	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7R73_RS10030	COG1160	GTP binding
H7R73_RS10035	COG1645	bacterial-type flagellum-dependent swarming motility
H7R73_RS10040	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
H7R73_RS10045	COG0047	phosphoribosylformylglycinamidine synthase activity
H7R73_RS10045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7R73_RS10050	COG1007	ATP synthesis coupled electron transport
H7R73_RS10055	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7R73_RS10065	COG0713	ATP synthesis coupled electron transport
H7R73_RS10070	COG0839	Belongs to the complex I subunit 6 family
H7R73_RS10075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7R73_RS10080	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
H7R73_RS10085	COG1034	ATP synthesis coupled electron transport
H7R73_RS10100	COG0649	NAD binding
H7R73_RS10100	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7R73_RS10105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7R73_RS10110	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7R73_RS10115	COG1360	Flagellar Motor Protein
H7R73_RS10120	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7R73_RS10135	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H7R73_RS10155	COG0724	RNA recognition motif
H7R73_RS10160	COG4989	oxidoreductase activity
H7R73_RS10185	COG0745	RESPONSE REGULATOR receiver
H7R73_RS10190	COG0583	DNA-binding transcription factor activity
H7R73_RS10200	COG3300	MHYT domain
H7R73_RS10200	COG5001	Diguanylate cyclase
H7R73_RS10205	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H7R73_RS10220	COG3385	transposase activity
H7R73_RS10245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7R73_RS10250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H7R73_RS10255	COG0539	negative regulation of cytoplasmic translation
H7R73_RS10260	COG0776	regulation of translation
H7R73_RS10270	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H7R73_RS10290	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H7R73_RS10295	COG0602	queuosine metabolic process
H7R73_RS10300	COG3530	Putative quorum-sensing-regulated virulence factor
H7R73_RS10305	COG2096	Adenosyltransferase
H7R73_RS10310	COG2916	Histone family protein nucleoid-structuring protein H-NS
H7R73_RS10315	COG1757	Na H antiporter
H7R73_RS10320	COG1435	thymidine kinase activity
H7R73_RS10340	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H7R73_RS10355	COG1349	DNA-binding transcription factor activity
H7R73_RS10360	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
H7R73_RS10370	COG3550	peptidyl-serine autophosphorylation
H7R73_RS10380	COG3385	transposase activity
H7R73_RS10475	COG3039	Transposase
H7R73_RS10510	COG3039	Transposase
H7R73_RS10515	COG3039	Transposase
H7R73_RS10550	COG0071	Belongs to the small heat shock protein (HSP20) family
H7R73_RS10555	COG0542	response to heat
H7R73_RS10565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7R73_RS10585	COG0501	Belongs to the peptidase M48B family
H7R73_RS10590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7R73_RS10595	COG3039	Transposase
H7R73_RS10615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7R73_RS10625	COG1205	dead DEAH box helicase
H7R73_RS10625	COG1111	helicase
H7R73_RS10630	COG0210	DNA helicase
H7R73_RS10680	COG2226	methyltransferase
H7R73_RS10710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H7R73_RS10725	COG2910	NAD(P)H-binding
H7R73_RS10730	COG0583	DNA-binding transcription factor activity
H7R73_RS10735	COG4977	sequence-specific DNA binding
H7R73_RS10735	COG1917	Cupin 2, conserved barrel domain protein
H7R73_RS10740	COG2200	EAL domain
H7R73_RS10745	COG3706	GGDEF domain
H7R73_RS10755	COG4774	siderophore transport
H7R73_RS10765	COG0583	DNA-binding transcription factor activity
H7R73_RS10770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7R73_RS10780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H7R73_RS10780	COG0617	tRNA 3'-terminal CCA addition
H7R73_RS10780	COG0517	IMP dehydrogenase activity
H7R73_RS10785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7R73_RS10790	COG3046	protein related to deoxyribodipyrimidine photolyase
H7R73_RS10805	COG4235	cytochrome complex assembly
H7R73_RS10805	COG3088	subunit of a heme lyase
H7R73_RS10810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7R73_RS10815	COG1138	Cytochrome C-type biogenesis protein
H7R73_RS10820	COG3301	Polysulphide reductase, NrfD
H7R73_RS10825	COG0437	4 iron, 4 sulfur cluster binding
H7R73_RS10830	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
H7R73_RS10840	COG3385	transposase activity
H7R73_RS10895	COG1846	Transcriptional regulator
H7R73_RS10905	COG0500	methyltransferase
H7R73_RS10915	COG2062	phosphohistidine phosphatase, SixA
H7R73_RS10925	COG0697	spore germination
H7R73_RS10940	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H7R73_RS10945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7R73_RS10955	COG4591	ABC-type transport system involved in lipoprotein release permease component
H7R73_RS10960	COG1136	(ABC) transporter
H7R73_RS10965	COG4591	ABC-type transport system involved in lipoprotein release permease component
H7R73_RS10970	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
H7R73_RS10980	COG0544	peptidyl-prolyl cis-trans isomerase activity
H7R73_RS10985	COG0740	serine-type endopeptidase activity
H7R73_RS10990	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H7R73_RS10995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H7R73_RS11000	COG0776	regulation of translation
H7R73_RS11005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7R73_RS11010	COG0488	(ABC) transporter
H7R73_RS11015	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7R73_RS11020	COG3162	membrane
H7R73_RS11035	COG1024	Enoyl-CoA hydratase
H7R73_RS11040	COG1115	amino acid carrier protein
H7R73_RS11050	COG3228	Belongs to the MtfA family
H7R73_RS11055	COG1584	GPR1 FUN34 yaaH family protein
H7R73_RS11065	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H7R73_RS11105	COG1024	Enoyl-CoA hydratase
H7R73_RS11110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7R73_RS11115	COG1960	acyl-CoA dehydrogenase activity
H7R73_RS11125	COG1960	acyl-CoA dehydrogenase activity
H7R73_RS11130	COG1024	Enoyl-CoA hydratase
H7R73_RS11135	COG1024	Enoyl-CoA hydratase
H7R73_RS11145	COG1028	Short-chain dehydrogenase reductase Sdr
H7R73_RS11155	COG0730	response to heat
H7R73_RS11170	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R73_RS11175	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R73_RS11180	COG1129	ABC transporter
H7R73_RS11185	COG1879	ABC-type sugar transport system periplasmic component
H7R73_RS11190	COG0583	DNA-binding transcription factor activity
H7R73_RS11200	COG0583	DNA-binding transcription factor activity
H7R73_RS11205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H7R73_RS11210	COG0243	molybdopterin cofactor binding
H7R73_RS11220	COG0583	DNA-binding transcription factor activity
H7R73_RS11225	COG2723	6-phospho-beta-galactosidase activity
H7R73_RS11235	COG0583	DNA-binding transcription factor activity
H7R73_RS11250	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
H7R73_RS11255	COG0673	inositol 2-dehydrogenase activity
H7R73_RS11260	COG0583	DNA-binding transcription factor activity
H7R73_RS11270	COG1560	Kdo2-lipid A biosynthetic process
H7R73_RS11275	COG1560	Kdo2-lipid A biosynthetic process
H7R73_RS11290	COG0417	DNA replication proofreading
H7R73_RS11320	COG0534	Mate efflux family protein
H7R73_RS11330	COG0307	riboflavin synthase, alpha
H7R73_RS11345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R73_RS11350	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
H7R73_RS11355	COG0697	spore germination
H7R73_RS11360	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7R73_RS11385	COG2996	Protein conserved in bacteria
H7R73_RS11400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7R73_RS11405	COG3099	Belongs to the UPF0263 family
H7R73_RS11410	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H7R73_RS11415	COG2894	cell division
H7R73_RS11420	COG0850	regulation of cytokinetic process
H7R73_RS11425	COG3100	YcgL domain-containing protein
H7R73_RS11430	COG2951	lytic endotransglycosylase activity
H7R73_RS11435	COG1760	l-serine dehydratase
H7R73_RS11440	COG1760	l-serine dehydratase
H7R73_RS11445	COG3123	guanosine phosphorylase activity
H7R73_RS11465	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H7R73_RS11470	COG2067	long-chain fatty acid transport protein
H7R73_RS11475	COG2067	long-chain fatty acid transport protein
H7R73_RS11485	COG1595	DNA-templated transcription, initiation
H7R73_RS11515	COG0714	Associated with various cellular activities
H7R73_RS11520	COG0183	Belongs to the thiolase family
H7R73_RS11525	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7R73_RS11525	COG1024	Enoyl-CoA hydratase
H7R73_RS11535	COG4681	YaeQ
H7R73_RS11555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R73_RS11570	COG3134	Outer membrane lipoprotein
H7R73_RS11575	COG0318	PFAM AMP-dependent synthetase and ligase
H7R73_RS11580	COG2378	regulation of single-species biofilm formation
H7R73_RS11590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H7R73_RS11590	COG0140	phosphoribosyl-ATP diphosphatase activity
H7R73_RS11595	COG0107	imidazoleglycerol-phosphate synthase activity
H7R73_RS11600	COG0784	Response regulator, receiver
H7R73_RS11600	COG2205	protein histidine kinase activity
H7R73_RS11600	COG2198	Histidine kinase
H7R73_RS11605	COG2199	diguanylate cyclase activity
H7R73_RS11610	COG3437	response regulator, receiver
H7R73_RS11615	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H7R73_RS11620	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H7R73_RS11625	COG0131	Imidazoleglycerol-phosphate dehydratase
H7R73_RS11625	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H7R73_RS11630	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7R73_RS11635	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H7R73_RS11640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H7R73_RS11650	COG1199	ATP-dependent helicase activity
H7R73_RS11655	COG1214	PFAM Peptidase M22, glycoprotease
H7R73_RS11665	COG0596	Alpha beta hydrolase
H7R73_RS11670	COG0318	PFAM AMP-dependent synthetase and ligase
H7R73_RS11685	COG0697	spore germination
H7R73_RS11695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7R73_RS11700	COG2832	Protein of unknown function (DUF454)
H7R73_RS11705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7R73_RS11715	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H7R73_RS11725	COG3039	Transposase
H7R73_RS11745	COG0583	DNA-binding transcription factor activity
H7R73_RS11755	COG3314	Sporulation integral membrane protein YlbJ
H7R73_RS11760	COG2197	response regulator
H7R73_RS11765	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H7R73_RS11765	COG0617	tRNA 3'-terminal CCA addition
H7R73_RS11765	COG0517	IMP dehydrogenase activity
H7R73_RS11770	COG1643	Atp-dependent helicase
H7R73_RS11780	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H7R73_RS11790	COG3437	response regulator, receiver
H7R73_RS11795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7R73_RS11800	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
H7R73_RS11805	COG0709	Synthesizes selenophosphate from selenide and ATP
H7R73_RS11820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H7R73_RS11825	COG0840	transmembrane signaling receptor activity
H7R73_RS11830	COG1254	Belongs to the acylphosphatase family
H7R73_RS11840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R73_RS11840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R73_RS11845	COG0489	protein tyrosine kinase activity
H7R73_RS11850	COG0572	uridine kinase
H7R73_RS11855	COG0717	Belongs to the dCTP deaminase family
H7R73_RS11860	COG0306	phosphate transporter
H7R73_RS11865	COG1530	ribonuclease E activity
H7R73_RS11870	COG0564	pseudouridine synthase activity
H7R73_RS11885	COG1399	metal-binding, possibly nucleic acid-binding protein
H7R73_RS11890	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H7R73_RS11895	COG0416	fatty acid biosynthetic process
H7R73_RS11900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7R73_RS11910	COG1028	Short-chain dehydrogenase reductase Sdr
H7R73_RS11915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7R73_RS11920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7R73_RS11925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7R73_RS11930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7R73_RS11935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H7R73_RS11940	COG0470	DNA polymerase III
H7R73_RS11945	COG0084	hydrolase, TatD family'
H7R73_RS11960	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7R73_RS11960	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
H7R73_RS11965	COG3008	intermembrane lipid transfer
H7R73_RS11970	COG2995	paraquat-inducible protein a
H7R73_RS11980	COG3141	response to X-ray
H7R73_RS11995	COG1067	ATP-dependent peptidase activity
H7R73_RS12000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7R73_RS12015	COG0488	(ABC) transporter
H7R73_RS12025	COG0116	Belongs to the methyltransferase superfamily
H7R73_RS12025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H7R73_RS12035	COG0167	dihydroorotate dehydrogenase activity
H7R73_RS12040	COG2902	Dehydrogenase
H7R73_RS12050	COG0308	aminopeptidase N
H7R73_RS12060	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
H7R73_RS12065	COG1956	GAF domain-containing protein
H7R73_RS12075	COG3278	Belongs to the heme-copper respiratory oxidase family
H7R73_RS12090	COG2010	Cytochrome c
H7R73_RS12100	COG2217	Heavy metal translocating P-type atpase
H7R73_RS12115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7R73_RS12120	COG0589	response to stress
H7R73_RS12125	COG0037	tRNA processing
H7R73_RS12140	COG0625	glutathione transferase activity
H7R73_RS12145	COG1869	D-ribose catabolic process
H7R73_RS12150	COG1129	ABC transporter
H7R73_RS12155	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R73_RS12160	COG1879	ABC-type sugar transport system periplasmic component
H7R73_RS12165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R73_RS12170	COG1609	Transcriptional regulator
H7R73_RS12175	COG5001	Diguanylate cyclase
H7R73_RS12175	COG3300	MHYT domain
H7R73_RS12205	COG0776	regulation of translation
H7R73_RS12210	COG0072	phenylalanine-tRNA ligase activity
H7R73_RS12210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R73_RS12215	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H7R73_RS12220	COG4974	Belongs to the 'phage' integrase family
H7R73_RS12240	COG3385	transposase activity
H7R73_RS12310	COG3385	transposase activity
H7R73_RS12335	COG4695	Portal protein
H7R73_RS12440	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H7R73_RS12470	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
H7R73_RS12475	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H7R73_RS12480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H7R73_RS12485	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H7R73_RS12490	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7R73_RS12520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7R73_RS12530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7R73_RS12535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7R73_RS12540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R73_RS12545	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H7R73_RS12550	COG3313	Fe-S protein
H7R73_RS12555	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7R73_RS12555	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7R73_RS12555	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H7R73_RS12560	COG1105	Belongs to the carbohydrate kinase PfkB family
H7R73_RS12565	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R73_RS12565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R73_RS12570	COG1609	Transcriptional regulator
H7R73_RS12575	COG0814	amino acid
H7R73_RS12585	COG5654	RES domain protein
H7R73_RS12590	COG0513	Belongs to the DEAD box helicase family
H7R73_RS12600	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H7R73_RS12605	COG2890	protein-(glutamine-N5) methyltransferase activity
H7R73_RS12610	COG2840	Smr protein MutS2
H7R73_RS12645	COG2824	Alkylphosphonate utilization operon protein PhnA
H7R73_RS12650	COG1280	lysine exporter protein (LysE YggA)
H7R73_RS12680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7R73_RS12685	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H7R73_RS12710	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7R73_RS12730	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
H7R73_RS12740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7R73_RS12745	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H7R73_RS12755	COG0205	6-phosphofructokinase activity
H7R73_RS12775	COG1011	Hydrolase
H7R73_RS12780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H7R73_RS12820	COG3593	DNA synthesis involved in DNA repair
H7R73_RS12835	COG0583	DNA-binding transcription factor activity
H7R73_RS12840	COG0730	response to heat
H7R73_RS12845	COG3148	PFAM DTW domain containing protein
H7R73_RS12850	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7R73_RS12860	COG0386	Belongs to the glutathione peroxidase family
H7R73_RS12865	COG0513	Belongs to the DEAD box helicase family
H7R73_RS12880	COG1742	UPF0060 membrane protein
H7R73_RS12905	COG2329	Antibiotic biosynthesis monooxygenase
H7R73_RS12910	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H7R73_RS12930	COG3243	poly(R)-hydroxyalkanoic acid synthase
H7R73_RS12940	COG2501	S4 domain
H7R73_RS12955	COG1132	(ABC) transporter
H7R73_RS12960	COG1132	(ABC) transporter
H7R73_RS12970	COG3118	belongs to the thioredoxin family
H7R73_RS12975	COG0471	metal ion transport
H7R73_RS12985	COG0058	SHG alpha-glucan phosphorylase activity
H7R73_RS13015	COG0814	amino acid
H7R73_RS13020	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H7R73_RS13025	COG0514	ATP-dependent DNA helicase (RecQ)
H7R73_RS13030	COG2766	serine protein kinase
H7R73_RS13035	COG2718	Belongs to the UPF0229 family
H7R73_RS13040	COG2719	SpoVR family
H7R73_RS13045	COG2186	Transcriptional regulator
H7R73_RS13055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H7R73_RS13060	COG0586	Pfam SNARE associated Golgi protein
H7R73_RS13070	COG0556	nucleotide-excision repair
H7R73_RS13080	COG2985	domain, Protein
H7R73_RS13080	COG0569	domain protein
H7R73_RS13085	COG0741	lytic transglycosylase activity
H7R73_RS13085	COG0739	heme binding
H7R73_RS13085	COG1196	nuclear chromosome segregation
H7R73_RS13090	COG3181	Tripartite tricarboxylate transporter family receptor
H7R73_RS13105	COG4565	transcriptional regulatory protein
H7R73_RS13110	COG3290	protein histidine kinase activity
H7R73_RS13115	COG1846	Transcriptional regulator
H7R73_RS13115	COG1940	carbohydrate kinase activity
H7R73_RS13120	COG0840	transmembrane signaling receptor activity
H7R73_RS13125	COG3012	SEC-C Motif Domain Protein
H7R73_RS13130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H7R73_RS13135	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
H7R73_RS13145	COG0247	lactate metabolic process
H7R73_RS13165	COG0519	Catalyzes the synthesis of GMP from XMP
H7R73_RS13165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7R73_RS13170	COG0516	GMP reductase activity
H7R73_RS13170	COG0517	IMP dehydrogenase activity
H7R73_RS13180	COG0366	Alpha amylase catalytic
H7R73_RS13180	COG1874	Beta-galactosidase
H7R73_RS13205	COG1570	exodeoxyribonuclease VII activity
H7R73_RS13215	COG2885	chlorophyll binding
H7R73_RS13235	COG2154	pterin-4-alpha-carbinolamine dehydratase
H7R73_RS13245	COG3768	UPF0283 membrane protein
H7R73_RS13250	COG3106	COG3106 Predicted ATPase
H7R73_RS13265	COG1842	Phage shock protein A
H7R73_RS13270	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7R73_RS13285	COG4171	peptide transport system, permease
H7R73_RS13295	COG4172	Belongs to the ABC transporter superfamily
H7R73_RS13305	COG1609	Transcriptional regulator
H7R73_RS13310	COG1263	PTS System
H7R73_RS13310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R73_RS13315	COG2723	6-phospho-beta-galactosidase activity
H7R73_RS13320	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H7R73_RS13325	COG1286	toxin biosynthetic process
H7R73_RS13330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H7R73_RS13335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7R73_RS13340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H7R73_RS13345	COG0531	amino acid
H7R73_RS13345	COG1674	ftsk spoiiie
H7R73_RS13355	COG0686	Belongs to the AlaDH PNT family
H7R73_RS13360	COG0492	ferredoxin-NADP+ reductase activity
H7R73_RS13365	COG3706	GGDEF domain
H7R73_RS13370	COG3134	Outer membrane lipoprotein
H7R73_RS13375	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H7R73_RS13380	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
H7R73_RS13385	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H7R73_RS13390	COG0542	response to heat
H7R73_RS13395	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H7R73_RS13400	COG1278	Cold shock
H7R73_RS13405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7R73_RS13410	COG2076	Multidrug Resistance protein
H7R73_RS13420	COG1944	ATP diphosphatase activity
H7R73_RS13425	COG2116	formate transmembrane transporter activity
H7R73_RS13430	COG1882	Formate acetyltransferase
H7R73_RS13435	COG2983	Belongs to the UPF0260 family
H7R73_RS13450	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7R73_RS13455	COG0045	succinate-CoA ligase (ADP-forming) activity
H7R73_RS13460	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7R73_RS13465	COG0567	Dehydrogenase, E1 component
H7R73_RS13480	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H7R73_RS13485	COG2009	succinate dehydrogenase
H7R73_RS13505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7R73_RS13510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7R73_RS13510	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H7R73_RS13520	COG3069	C4-dicarboxylate transmembrane transporter activity
H7R73_RS13535	COG1451	nucleotide metabolic process
H7R73_RS13550	COG0254	rRNA binding
H7R73_RS13555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H7R73_RS13565	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R73_RS13570	COG1129	ABC transporter
H7R73_RS13575	COG1879	ABC-type sugar transport system periplasmic component
H7R73_RS13580	COG1069	ribulokinase activity
H7R73_RS13590	COG2160	L-arabinose isomerase activity
H7R73_RS13595	COG0583	DNA-binding transcription factor activity
H7R73_RS13600	COG0436	Aminotransferase
H7R73_RS13605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7R73_RS13620	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H7R73_RS13620	COG0392	lysyltransferase activity
H7R73_RS13625	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7R73_RS13840	COG1846	Transcriptional regulator
H7R73_RS13855	COG1396	sequence-specific DNA binding
H7R73_RS13860	COG1396	sequence-specific DNA binding
H7R73_RS13885	COG2314	TM2 domain
H7R73_RS13940	COG0582	viral genome integration into host DNA
H7R73_RS13945	COG2925	Exonuclease
H7R73_RS13955	COG3345	alpha-galactosidase
H7R73_RS13960	COG1380	Effector of murein hydrolase LrgA
H7R73_RS13965	COG1346	cytolysis
H7R73_RS13970	COG0295	cytidine deaminase activity
H7R73_RS13975	COG1022	Amp-dependent synthetase and ligase
H7R73_RS13990	COG0861	Integral membrane protein TerC family
H7R73_RS13995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7R73_RS14000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H7R73_RS14005	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H7R73_RS14045	COG4771	TonB-dependent receptor
H7R73_RS14050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R73_RS14055	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R73_RS14060	COG1120	ATPase activity
H7R73_RS14075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7R73_RS14085	COG1028	Short-chain dehydrogenase reductase Sdr
H7R73_RS14090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7R73_RS14095	COG1535	isochorismatase
H7R73_RS14095	COG3433	isochorismatase activity
H7R73_RS14100	COG1021	2,3-dihydroxybenzoate-AMP ligase
H7R73_RS14125	COG5001	Diguanylate cyclase
H7R73_RS14125	COG3300	MHYT domain
H7R73_RS14140	COG0840	transmembrane signaling receptor activity
H7R73_RS14145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R73_RS14150	COG3788	relative of glutathione S-transferase, MAPEG superfamily
H7R73_RS14155	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H7R73_RS14160	COG0563	adenylate kinase activity
H7R73_RS14165	COG0326	Molecular chaperone. Has ATPase activity
H7R73_RS14170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7R73_RS14180	COG3158	transport of potassium into the cell
H7R73_RS14185	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
H7R73_RS14190	COG0298	carbon dioxide binding
H7R73_RS14200	COG0309	Hydrogenase expression formation protein (HypE)
H7R73_RS14205	COG0375	protein maturation
H7R73_RS14210	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H7R73_RS14215	COG3842	ATPase activity
H7R73_RS14220	COG0444	Belongs to the ABC transporter superfamily
H7R73_RS14225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R73_RS14230	COG0601	transmembrane transport
H7R73_RS14240	COG1773	rubredoxin
H7R73_RS14245	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H7R73_RS14250	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
H7R73_RS14255	COG5557	Pfam Polysulphide reductase, NrfD
H7R73_RS14260	COG0437	4 iron, 4 sulfur cluster binding
H7R73_RS14265	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
H7R73_RS14310	COG3829	transcription factor binding
H7R73_RS14380	COG3385	transposase activity
H7R73_RS14395	COG3209	COG3209 Rhs family protein
H7R73_RS14405	COG3501	Rhs element vgr protein
H7R73_RS14455	COG3385	transposase activity
H7R73_RS14480	COG0659	secondary active sulfate transmembrane transporter activity
H7R73_RS14500	COG0300	oxidoreductase activity
H7R73_RS14505	COG2308	Evidence 4 Homologs of previously reported genes of
H7R73_RS14540	COG0672	)-iron permease
H7R73_RS14565	COG2814	Major facilitator Superfamily
H7R73_RS14585	COG1136	(ABC) transporter
H7R73_RS14590	COG0577	efflux transmembrane transporter activity
H7R73_RS14620	COG1139	Iron-sulfur cluster binding protein
H7R73_RS14625	COG0247	lactate metabolic process
H7R73_RS14630	COG1620	l-lactate permease
H7R73_RS14635	COG0583	DNA-binding transcription factor activity
H7R73_RS14660	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7R73_RS14665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7R73_RS14665	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H7R73_RS14670	COG0527	aspartate kinase activity
H7R73_RS14680	COG1368	sulfuric ester hydrolase activity
H7R73_RS14685	COG0393	Putative heavy-metal-binding
H7R73_RS14695	COG1252	NADH dehydrogenase
H7R73_RS14700	COG3150	esterase
H7R73_RS14705	COG1164	Oligoendopeptidase f
H7R73_RS14710	COG1164	Oligoendopeptidase f
H7R73_RS14715	COG2354	Protein conserved in bacteria
H7R73_RS14730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7R73_RS14735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7R73_RS14770	COG0537	adenosine 5'-monophosphoramidase activity
H7R73_RS14785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H7R73_RS14805	COG1301	dicarboxylic acid transport
H7R73_RS14815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7R73_RS14820	COG0861	Integral membrane protein TerC family
H7R73_RS14830	COG0444	Belongs to the ABC transporter superfamily
H7R73_RS14835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R73_RS14840	COG0601	transmembrane transport
H7R73_RS14850	COG2095	MarC family integral membrane protein
H7R73_RS14855	COG1454	alcohol dehydrogenase
H7R73_RS14855	COG1012	belongs to the aldehyde dehydrogenase family
H7R73_RS14865	COG3275	phosphorelay sensor kinase activity
H7R73_RS14870	COG3279	Response regulator of the LytR AlgR family
H7R73_RS14875	COG1966	Carbon starvation protein
H7R73_RS14880	COG3264	Mechanosensitive ion channel
H7R73_RS14880	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H7R73_RS14890	COG1566	PFAM secretion protein HlyD family protein
H7R73_RS14895	COG1061	Type III restriction enzyme res subunit
H7R73_RS14900	COG2027	D-alanyl-D-alanine carboxypeptidase
H7R73_RS14905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H7R73_RS14915	COG0436	Aminotransferase
H7R73_RS14920	COG1288	antiporter activity
H7R73_RS14925	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H7R73_RS14945	COG0697	spore germination
H7R73_RS14950	COG4657	Part of a membrane complex involved in electron transport
H7R73_RS14955	COG2878	Part of a membrane complex involved in electron transport
H7R73_RS14965	COG4658	electron transport chain
H7R73_RS14970	COG4659	FMN binding
H7R73_RS14975	COG4660	Part of a membrane complex involved in electron transport
H7R73_RS14980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7R73_RS14985	COG0346	lactoylglutathione lyase activity
H7R73_RS14990	COG0840	transmembrane signaling receptor activity
H7R73_RS15005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7R73_RS15015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7R73_RS15020	COG1086	Polysaccharide biosynthesis protein
H7R73_RS15025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7R73_RS15035	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
H7R73_RS15040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7R73_RS15055	COG2089	acid synthase
H7R73_RS15090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7R73_RS15110	COG0301	tRNA thio-modification
H7R73_RS15110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7R73_RS15120	COG4953	penicillin-binding protein 1C
H7R73_RS15125	COG2373	Large extracellular alpha-helical protein
H7R73_RS15130	COG0628	permease
H7R73_RS15155	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R73_RS15165	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H7R73_RS15175	COG4160	amino acid transport
H7R73_RS15185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R73_RS15195	COG2431	L-lysine efflux transmembrane transporter activity
H7R73_RS15200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H7R73_RS15205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R73_RS15230	COG1393	Belongs to the ArsC family
H7R73_RS15240	COG4783	chaperone-mediated protein folding
H7R73_RS15245	COG0425	Belongs to the sulfur carrier protein TusA family
H7R73_RS15260	COG0596	Alpha beta hydrolase
H7R73_RS15270	COG3842	ATPase activity
H7R73_RS15275	COG3833	ABC-type maltose transport systems, permease component
H7R73_RS15280	COG1175	transmembrane transport
H7R73_RS15290	COG3081	Nucleoid-associated protein
H7R73_RS15295	COG3082	Protein of unknown function (DUF1414)
H7R73_RS15300	COG3083	sulfuric ester hydrolase activity
H7R73_RS15305	COG4771	TonB-dependent receptor
H7R73_RS15310	COG1770	oligopeptidase
H7R73_RS15330	COG4574	serine-type endopeptidase inhibitor activity
H7R73_RS15335	COG3085	chromosome segregation
H7R73_RS15345	COG0287	Prephenate dehydrogenase
H7R73_RS15345	COG1605	Chorismate mutase
H7R73_RS15350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7R73_RS15355	COG0584	glycerophosphoryl diester phosphodiesterase
H7R73_RS15365	COG1349	DNA-binding transcription factor activity
H7R73_RS15370	COG2271	Major facilitator Superfamily
H7R73_RS15375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H7R73_RS15380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7R73_RS15385	COG0583	DNA-binding transcription factor activity
H7R73_RS15405	COG0656	L-ascorbic acid biosynthetic process
H7R73_RS15410	COG2814	Major facilitator Superfamily
H7R73_RS15420	COG1294	oxidase, subunit
H7R73_RS15425	COG1271	oxidase subunit
H7R73_RS15430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R73_RS15440	COG2979	Protein of unknown function (DUF533)
H7R73_RS15460	COG0583	DNA-binding transcription factor activity
H7R73_RS15470	COG2807	transmembrane transport
H7R73_RS15475	COG1187	pseudouridine synthase activity
H7R73_RS15480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7R73_RS15495	COG1403	HNH endonuclease
H7R73_RS15520	COG1166	arginine decarboxylase activity
H7R73_RS15525	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7R73_RS15540	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H7R73_RS15555	COG0583	DNA-binding transcription factor activity
H7R73_RS15565	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H7R73_RS15570	COG0840	transmembrane signaling receptor activity
H7R73_RS15575	COG0302	gtp cyclohydrolase
H7R73_RS15585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7R73_RS15600	COG2267	carboxylic ester hydrolase activity
H7R73_RS15605	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H7R73_RS15620	COG0314	molybdopterin synthase activity
H7R73_RS15625	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H7R73_RS15630	COG0315	cyclic pyranopterin monophosphate synthase activity
H7R73_RS15635	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7R73_RS15640	COG3005	denitrification pathway
H7R73_RS15650	COG0348	domain, Protein
H7R73_RS15655	COG0437	4 iron, 4 sulfur cluster binding
H7R73_RS15660	COG0243	molybdopterin cofactor binding
H7R73_RS15670	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R73_RS15670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R73_RS15675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H7R73_RS15680	COG3850	Histidine kinase
H7R73_RS15685	COG2197	response regulator
H7R73_RS15710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H7R73_RS15720	COG0121	glutamine amidotransferase
H7R73_RS15725	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H7R73_RS15730	COG1960	acyl-CoA dehydrogenase activity
H7R73_RS15735	COG0784	Response regulator, receiver
H7R73_RS15735	COG3437	response regulator, receiver
H7R73_RS15745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R73_RS15750	COG0328	RNA-DNA hybrid ribonuclease activity
H7R73_RS15755	COG2226	methyltransferase
H7R73_RS15760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7R73_RS15765	COG1388	LysM domain
H7R73_RS15765	COG0741	lytic transglycosylase activity
H7R73_RS15780	COG1607	acyl-coa hydrolase
H7R73_RS15795	COG0741	lytic transglycosylase activity
H7R73_RS15805	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H7R73_RS15830	COG2911	Protein conserved in bacteria
H7R73_RS15835	COG0729	surface antigen
H7R73_RS15845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7R73_RS15855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7R73_RS15860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7R73_RS15865	COG4134	Bacterial extracellular solute-binding protein
H7R73_RS15875	COG4136	ATPase activity
H7R73_RS15880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7R73_RS15885	COG2951	lytic endotransglycosylase activity
H7R73_RS15890	COG1846	Transcriptional regulator
H7R73_RS15900	COG0033	Phosphoglucomutase
H7R73_RS15905	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
H7R73_RS15910	COG0596	Alpha beta hydrolase
H7R73_RS15925	COG0716	FMN binding
H7R73_RS15935	COG0735	belongs to the Fur family
H7R73_RS15940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7R73_RS15950	COG1263	PTS System
H7R73_RS15950	COG2190	(PTS) system
H7R73_RS15950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R73_RS15955	COG0363	glucosamine-6-phosphate deaminase activity
H7R73_RS15960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H7R73_RS15965	COG1846	Transcriptional regulator
H7R73_RS15965	COG1940	carbohydrate kinase activity
H7R73_RS15970	COG2194	sulfuric ester hydrolase activity
H7R73_RS15975	COG0217	transcriptional regulatory protein
H7R73_RS15980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H7R73_RS15985	COG1801	Protein of unknown function DUF72
H7R73_RS15990	COG4106	trans-aconitate 2-methyltransferase activity
H7R73_RS15995	COG0500	methyltransferase
H7R73_RS16015	COG0583	DNA-binding transcription factor activity
H7R73_RS16020	COG0791	NLP P60 protein
H7R73_RS16035	COG1309	transcriptional regulator
H7R73_RS16045	COG1454	alcohol dehydrogenase
H7R73_RS16070	COG0534	Mate efflux family protein
H7R73_RS16085	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H7R73_RS16085	COG0674	pyruvate-flavodoxin oxidoreductase activity
H7R73_RS16085	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H7R73_RS16085	COG1013	pyruvate-flavodoxin oxidoreductase activity
H7R73_RS16095	COG3217	Mosc domain protein beta barrel domain protein
H7R73_RS16095	COG0633	Ferredoxin
H7R73_RS16095	COG3217	Mosc domain protein beta barrel domain protein
H7R73_RS16095	COG0633	Ferredoxin
H7R73_RS16100	COG0501	Belongs to the peptidase M48B family
H7R73_RS16105	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H7R73_RS16110	COG1073	alpha beta
H7R73_RS16110	COG2226	methyltransferase
H7R73_RS16115	COG0156	8-amino-7-oxononanoate synthase activity
H7R73_RS16120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H7R73_RS16140	COG0017	Asparaginyl-tRNA synthetase
H7R73_RS16145	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H7R73_RS16155	COG1473	amidohydrolase
H7R73_RS16160	COG3069	C4-dicarboxylate transmembrane transporter activity
H7R73_RS16170	COG1393	Belongs to the ArsC family
H7R73_RS16175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7R73_RS16180	COG1876	peptidase activity
H7R73_RS16190	COG3263	regulation of cellular component size
H7R73_RS16200	COG1280	lysine exporter protein (LysE YggA)
H7R73_RS16225	COG1957	nucleoside hydrolase
H7R73_RS16240	COG1454	alcohol dehydrogenase
H7R73_RS16245	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7R73_RS16250	COG0702	epimerase
H7R73_RS16255	COG2914	Belongs to the UPF0125 (RnfH) family
H7R73_RS16260	COG2867	negative regulation of translational initiation
H7R73_RS16265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H7R73_RS16275	COG0582	viral genome integration into host DNA
H7R73_RS16305	COG4735	regulation of single-species biofilm formation
H7R73_RS16355	COG3153	acetyltransferase
H7R73_RS16385	COG0259	pyridoxamine-phosphate oxidase activity
H7R73_RS16400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7R73_RS16400	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7R73_RS16405	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H7R73_RS16420	COG0457	Tetratricopeptide repeat
H7R73_RS16430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7R73_RS16435	COG1138	Cytochrome C-type biogenesis protein
H7R73_RS16440	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
H7R73_RS16445	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7R73_RS16450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7R73_RS16455	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7R73_RS16470	COG0835	chemotaxis
H7R73_RS16480	COG1192	Involved in chromosome partitioning
H7R73_RS16485	COG1360	Flagellar Motor Protein
H7R73_RS16490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7R73_RS16495	COG2201	protein-glutamate methylesterase activity
H7R73_RS16500	COG2198	Histidine kinase
H7R73_RS16500	COG0784	Response regulator, receiver
H7R73_RS16500	COG0643	Histidine kinase
H7R73_RS16505	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H7R73_RS16530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7R73_RS16540	COG1684	flagellar biosynthetic protein fliR
H7R73_RS16595	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7R73_RS16605	COG1677	Flagellar hook-basal body complex protein FliE
H7R73_RS16620	COG1393	Belongs to the ArsC family
H7R73_RS16625	COG0798	PFAM Bile acid sodium symporter
H7R73_RS16630	COG0640	Transcriptional regulator
H7R73_RS16635	COG3385	transposase activity
H7R73_RS16645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7R73_RS16660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R73_RS16665	COG0444	Belongs to the ABC transporter superfamily
H7R73_RS16670	COG4608	Belongs to the ABC transporter superfamily
H7R73_RS16680	COG2971	BadF BadG BcrA BcrD
H7R73_RS16690	COG0840	transmembrane signaling receptor activity
H7R73_RS16710	COG3724	N-succinylarginine dihydrolase activity
H7R73_RS16715	COG0616	signal peptide processing
H7R73_RS16720	COG1028	Short-chain dehydrogenase reductase Sdr
H7R73_RS16725	COG0583	DNA-binding transcription factor activity
H7R73_RS16735	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H7R73_RS16745	COG0583	DNA-binding transcription factor activity
H7R73_RS16750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H7R73_RS16755	COG1881	PFAM PEBP family protein
H7R73_RS16765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7R73_RS16770	COG0739	heme binding
H7R73_RS16775	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H7R73_RS16795	COG3385	transposase activity
H7R73_RS16815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7R73_RS16825	COG3091	SprT-like family
H7R73_RS16835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7R73_RS16840	COG0189	ligase activity
H7R73_RS16850	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7R73_RS16870	COG1115	amino acid carrier protein
H7R73_RS16875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7R73_RS16890	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H7R73_RS16900	COG1301	dicarboxylic acid transport
H7R73_RS16905	COG3385	transposase activity
H7R73_RS16910	COG3385	transposase activity
H7R73_RS16960	COG0490	domain, Protein
H7R73_RS16960	COG0471	metal ion transport
H7R73_RS16970	COG0657	acetylesterase activity
H7R73_RS16985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R73_RS17000	COG1012	belongs to the aldehyde dehydrogenase family
H7R73_RS17010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7R73_RS17025	COG0180	Tryptophanyl-tRNA synthetase
H7R73_RS17035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7R73_RS17040	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H7R73_RS17050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H7R73_RS17055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7R73_RS17085	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H7R73_RS17090	COG0583	DNA-binding transcription factor activity
H7R73_RS17105	COG0583	DNA-binding transcription factor activity
H7R73_RS17120	COG3121	Chaperone
H7R73_RS17130	COG3121	Chaperone
H7R73_RS17140	COG0739	heme binding
H7R73_RS17150	COG3264	Mechanosensitive ion channel
H7R73_RS17150	COG1511	domain protein
H7R73_RS17155	COG0584	glycerophosphoryl diester phosphodiesterase
H7R73_RS17165	COG1053	succinate dehydrogenase
H7R73_RS17170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7R73_RS17175	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
H7R73_RS17180	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
H7R73_RS17195	COG3214	Protein conserved in bacteria
H7R73_RS17200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7R73_RS17220	COG0300	oxidoreductase activity
H7R73_RS17250	COG4067	protein conserved in archaea
H7R73_RS17250	COG0189	ligase activity
H7R73_RS17255	COG0516	GMP reductase activity
H7R73_RS17265	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H7R73_RS17270	COG2011	ABC-type metal ion transport system permease component
H7R73_RS17275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7R73_RS17280	COG1464	Belongs to the NlpA lipoprotein family
H7R73_RS17295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7R73_RS17305	COG2199	diguanylate cyclase activity
H7R73_RS17320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R73_RS17335	COG1335	isochorismatase
H7R73_RS17340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R73_RS17345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7R73_RS17350	COG1702	phosphate starvation-inducible protein PhoH
H7R73_RS17355	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H7R73_RS17360	COG4535	Mg2 and Co2 transporter CorC
H7R73_RS17365	COG0815	Transfers the fatty acyl group on membrane lipoproteins
H7R73_RS17370	COG2888	peptidyl-tyrosine sulfation
H7R73_RS17375	COG0495	leucyl-tRNA aminoacylation
H7R73_RS17390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H7R73_RS17395	COG0799	negative regulation of ribosome biogenesis
H7R73_RS17400	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H7R73_RS17405	COG0768	penicillin binding
H7R73_RS17410	COG0772	Belongs to the SEDS family
H7R73_RS17415	COG2951	lytic endotransglycosylase activity
H7R73_RS17420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7R73_RS17425	COG1686	Belongs to the peptidase S11 family
H7R73_RS17430	COG2921	Belongs to the UPF0250 family
H7R73_RS17435	COG0321	lipoyl(octanoyl) transferase activity
H7R73_RS17440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H7R73_RS17450	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H7R73_RS17465	COG0789	Transcriptional regulator
H7R73_RS17470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7R73_RS17480	COG1970	mechanosensitive ion channel activity
H7R73_RS17485	COG4974	Belongs to the 'phage' integrase family
H7R73_RS17495	COG0312	modulator of DNA gyrase
H7R73_RS17500	COG0312	modulator of DNA gyrase
H7R73_RS17515	COG0826	peptidase U32
H7R73_RS17520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R73_RS17525	COG1422	Protein of unknown function (DUF1090)
H7R73_RS17530	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H7R73_RS17535	COG2211	Major facilitator Superfamily
H7R73_RS17540	COG1185	polyribonucleotide nucleotidyltransferase activity
H7R73_RS17545	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H7R73_RS17550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7R73_RS17555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H7R73_RS17560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H7R73_RS17565	COG0195	Participates in both transcription termination and antitermination
H7R73_RS17570	COG0779	Required for maturation of 30S ribosomal subunits
H7R73_RS17585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H7R73_RS17590	COG0149	triose-phosphate isomerase activity
H7R73_RS17595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7R73_RS17600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H7R73_RS17610	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H7R73_RS17615	COG1534	Rna-binding protein
H7R73_RS17630	COG1360	Flagellar Motor Protein
H7R73_RS17635	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7R73_RS17640	COG1722	exodeoxyribonuclease VII activity
H7R73_RS17645	COG0142	geranyltranstransferase activity
H7R73_RS17650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H7R73_RS17655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R73_RS17660	COG0601	transmembrane transport
H7R73_RS17670	COG4172	Belongs to the ABC transporter superfamily
H7R73_RS17675	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7R73_RS17680	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H7R73_RS17685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7R73_RS17690	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H7R73_RS17705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7R73_RS17705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7R73_RS17710	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H7R73_RS17720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H7R73_RS17730	COG3381	protein complex oligomerization
H7R73_RS17745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7R73_RS17750	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H7R73_RS17755	COG0511	ligase activity, forming carbon-carbon bonds
H7R73_RS17760	COG0439	Biotin carboxylase
H7R73_RS17765	COG3924	membrane
H7R73_RS17770	COG4145	pantothenate transmembrane transporter activity
H7R73_RS17775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R73_RS17775	COG2190	(PTS) system
H7R73_RS17775	COG1263	PTS System
H7R73_RS17780	COG0583	DNA-binding transcription factor activity
H7R73_RS17785	COG0604	alcohol dehydrogenase
H7R73_RS17790	COG2264	protein methyltransferase activity
H7R73_RS17810	COG0778	Nitroreductase
H7R73_RS17815	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R73_RS17815	COG1902	pentaerythritol trinitrate reductase activity
H7R73_RS17820	COG0616	signal peptide processing
H7R73_RS17840	COG3139	Protein of unknown function (DUF1315)
H7R73_RS17845	COG0252	asparaginase activity
H7R73_RS17850	COG0786	glutamate:sodium symporter activity
H7R73_RS17865	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H7R73_RS17870	COG0384	phenazine biosynthesis protein PhzF
H7R73_RS17875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7R73_RS17880	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R73_RS17885	COG0175	sulfate reduction
H7R73_RS17890	COG2113	Glycine betaine
H7R73_RS17895	COG4176	ABC-type proline glycine betaine transport system permease component
H7R73_RS17900	COG4175	Glycine betaine
H7R73_RS17910	COG3610	response to peptide
H7R73_RS17915	COG2966	Psort location CytoplasmicMembrane, score
H7R73_RS17925	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7R73_RS17945	COG2313	pseudouridylate synthase activity
H7R73_RS17950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R73_RS17955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R73_RS17955	COG2146	nitrite reductase [NAD(P)H] activity
H7R73_RS17960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R73_RS17960	COG2146	nitrite reductase [NAD(P)H] activity
H7R73_RS17965	COG1116	anion transmembrane transporter activity
H7R73_RS17970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R73_RS17975	COG1116	anion transmembrane transporter activity
H7R73_RS17975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R73_RS17985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7R73_RS17985	COG1648	precorrin-2 dehydrogenase activity
H7R73_RS17990	COG0243	molybdopterin cofactor binding
H7R73_RS18015	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7R73_RS18030	COG1073	alpha beta
H7R73_RS18035	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
H7R73_RS18040	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7R73_RS18045	COG4608	Belongs to the ABC transporter superfamily
H7R73_RS18050	COG0444	Belongs to the ABC transporter superfamily
H7R73_RS18060	COG4239	(ABC) transporter, permease
H7R73_RS18065	COG4174	ABC transporter (Permease)
H7R73_RS18075	COG4206	TonB-dependent receptor
H7R73_RS18085	COG0811	peptide transport
H7R73_RS18090	COG0811	peptide transport
H7R73_RS18095	COG0848	biopolymer transport protein
H7R73_RS18155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7R73_RS18160	COG0840	transmembrane signaling receptor activity
H7R73_RS18170	COG1278	Cold shock
H7R73_RS18205	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H7R73_RS18210	COG1162	GTPase activity
H7R73_RS18215	COG0688	phosphatidylethanolamine metabolic process
H7R73_RS18220	COG4628	conserved protein (DUF2132)
H7R73_RS18240	COG3300	MHYT domain
H7R73_RS18240	COG5001	Diguanylate cyclase
H7R73_RS18245	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
H7R73_RS18265	COG2189	Belongs to the N(4) N(6)-methyltransferase family
H7R73_RS18295	COG4974	Belongs to the 'phage' integrase family
H7R73_RS18325	COG0582	viral genome integration into host DNA
H7R73_RS18350	COG1132	(ABC) transporter
H7R73_RS18385	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7R73_RS18390	COG2897	thiosulfate sulfurtransferase activity
H7R73_RS18395	COG2066	Belongs to the glutaminase family
H7R73_RS18400	COG3171	Protein conserved in bacteria
H7R73_RS18405	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7R73_RS18415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R73_RS18420	COG2200	EAL domain
H7R73_RS18425	COG1090	epimerase
H7R73_RS18430	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H7R73_RS18435	COG4181	ATPase activity
H7R73_RS18440	COG2755	lipolytic protein G-D-S-L family
H7R73_RS18445	COG0784	Response regulator, receiver
H7R73_RS18445	COG0835	chemotaxis
H7R73_RS18455	COG0516	GMP reductase activity
H7R73_RS18455	COG0517	IMP dehydrogenase activity
H7R73_RS18460	COG0488	(ABC) transporter
H7R73_RS18470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H7R73_RS18515	COG0789	Transcriptional regulator
H7R73_RS18525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7R73_RS18535	COG0668	transmembrane transport
H7R73_RS18545	COG2731	YhcH YjgK YiaL family protein
H7R73_RS18555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7R73_RS18560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7R73_RS18565	COG3227	Zinc metalloprotease (Elastase)
H7R73_RS18570	COG0583	DNA-binding transcription factor activity
H7R73_RS18575	COG0477	Major facilitator Superfamily
H7R73_RS18585	COG2985	domain, Protein
H7R73_RS18585	COG0569	domain protein
H7R73_RS18590	COG1272	protein, Hemolysin III
H7R73_RS18595	COG0076	glutamate decarboxylase activity
H7R73_RS18600	COG2917	probably involved in intracellular septation
H7R73_RS18605	COG2350	Protein conserved in bacteria
H7R73_RS18615	COG1555	photosystem II stabilization
H7R73_RS18620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7R73_RS18625	COG3104	oligopeptide transport
H7R73_RS18630	COG0745	RESPONSE REGULATOR receiver
H7R73_RS18660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R73_RS18675	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H7R73_RS18680	COG1280	lysine exporter protein (LysE YggA)
H7R73_RS18705	COG0316	Belongs to the HesB IscA family
H7R73_RS18715	COG0038	chloride channel
H7R73_RS18720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7R73_RS18735	COG0671	phosphoesterase, PA-phosphatase related
H7R73_RS18745	COG0583	DNA-binding transcription factor activity
H7R73_RS18760	COG0346	lactoylglutathione lyase activity
H7R73_RS18765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7R73_RS18770	COG1643	Atp-dependent helicase
H7R73_RS18780	COG1489	DNA binding
H7R73_RS18785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7R73_RS18790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7R73_RS18800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7R73_RS18805	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H7R73_RS18810	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H7R73_RS18820	COG0842	Transport permease protein
H7R73_RS18825	COG1131	(ABC) transporter
H7R73_RS18840	COG0163	prenyltransferase activity
H7R73_RS18845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7R73_RS18850	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H7R73_RS18865	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H7R73_RS18880	COG1136	(ABC) transporter
H7R73_RS18900	COG0840	transmembrane signaling receptor activity
H7R73_RS18945	COG0529	Catalyzes the synthesis of activated sulfate
H7R73_RS18950	COG0471	metal ion transport
H7R73_RS18950	COG3273	potassium ion transport
H7R73_RS18955	COG2895	sulfate adenylyltransferase (ATP) activity
H7R73_RS18960	COG0175	sulfate reduction
H7R73_RS18965	COG1648	precorrin-2 dehydrogenase activity
H7R73_RS18965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7R73_RS18970	COG0330	HflC and HflK could
H7R73_RS18975	COG1585	Membrane protein implicated in regulation of membrane protease activity
H7R73_RS18985	COG0673	inositol 2-dehydrogenase activity
H7R73_RS18995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H7R73_RS19000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7R73_RS19005	COG3036	rescue of stalled ribosome
H7R73_RS19020	COG0138	bifunctional purine biosynthesis protein purh
H7R73_RS19060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H7R73_RS19065	COG0358	DNA primase activity
H7R73_RS19070	COG1610	YqeY-like protein
H7R73_RS19075	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H7R73_RS19080	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H7R73_RS19090	COG4942	peptidase
H7R73_RS19090	COG1388	LysM domain
H7R73_RS19095	COG1238	metal cluster binding
H7R73_RS19100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H7R73_RS19105	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H7R73_RS19110	COG0585	pseudouridine synthase activity
H7R73_RS19120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H7R73_RS19125	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H7R73_RS19130	COG0148	phosphopyruvate hydratase activity
H7R73_RS19135	COG0504	CTP synthase activity
H7R73_RS19140	COG3956	TIGRFAM MazG family protein
H7R73_RS19145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7R73_RS19150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7R73_RS19160	COG4807	Protein conserved in bacteria
H7R73_RS19165	COG3023	N-Acetylmuramoyl-L-alanine amidase
H7R73_RS19170	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H7R73_RS19175	COG1381	Involved in DNA repair and RecF pathway recombination
H7R73_RS19185	COG0571	ribonuclease III activity
H7R73_RS19190	COG0681	Belongs to the peptidase S26 family
H7R73_RS19195	COG0481	GTPase activity
H7R73_RS19210	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
H7R73_RS19215	COG1595	DNA-templated transcription, initiation
H7R73_RS19220	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H7R73_RS19230	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H7R73_RS19235	COG0354	folic acid binding
H7R73_RS19240	COG0583	DNA-binding transcription factor activity
H7R73_RS19275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7R73_RS19285	COG0126	phosphoglycerate kinase activity
H7R73_RS19290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7R73_RS19295	COG1940	carbohydrate kinase activity
H7R73_RS19300	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H7R73_RS19310	COG4991	sh3 domain protein
H7R73_RS19315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7R73_RS19330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H7R73_RS19335	COG1028	Short-chain dehydrogenase reductase Sdr
H7R73_RS19345	COG1505	serine-type exopeptidase activity
H7R73_RS19350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7R73_RS19355	COG0765	amino acid transport
H7R73_RS19360	COG0765	amino acid transport
H7R73_RS19365	COG1126	abc transporter atp-binding protein
H7R73_RS19370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R73_RS19375	COG3174	membrane
H7R73_RS19380	COG0110	maltose O-acetyltransferase activity
H7R73_RS19410	COG1942	4-Oxalocrotonate Tautomerase
H7R73_RS19420	COG0583	DNA-binding transcription factor activity
H7R73_RS19425	COG0165	Argininosuccinate lyase
H7R73_RS19430	COG0137	argininosuccinate synthase activity
H7R73_RS19440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7R73_RS19445	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H7R73_RS19455	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H7R73_RS19465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H7R73_RS19500	COG0583	DNA-binding transcription factor activity
H7R73_RS19505	COG1380	Effector of murein hydrolase LrgA
H7R73_RS19510	COG1346	cytolysis
H7R73_RS19515	COG0527	aspartate kinase activity
H7R73_RS19515	COG0460	homoserine dehydrogenase
H7R73_RS19520	COG0626	cystathionine gamma-synthase activity
H7R73_RS19535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R73_RS19540	COG0814	amino acid
H7R73_RS19545	COG1218	3'(2'),5'-bisphosphate nucleotidase
H7R73_RS19550	COG0494	nUDIX hydrolase
H7R73_RS19555	COG1011	Hydrolase
H7R73_RS19560	COG1902	pentaerythritol trinitrate reductase activity
H7R73_RS19570	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7R73_RS19585	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H7R73_RS19595	COG3156	type II secretion system protein K
H7R73_RS19605	COG4795	General secretion pathway protein
H7R73_RS19610	COG2165	general secretion pathway protein
H7R73_RS19620	COG2165	general secretion pathway protein
H7R73_RS19625	COG1459	type II secretion system
H7R73_RS19630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7R73_RS19640	COG3031	protein transport across the cell outer membrane
H7R73_RS19650	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H7R73_RS19655	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H7R73_RS19670	COG0456	acetyltransferase
H7R73_RS19675	COG3133	Outer membrane lipoprotein
H7R73_RS19680	COG3025	triphosphatase activity
H7R73_RS19685	COG1392	Phosphate transport regulator
H7R73_RS19690	COG0306	phosphate transporter
H7R73_RS19695	COG0617	tRNA 3'-terminal CCA addition
H7R73_RS19700	COG3267	Type II secretory pathway component ExeA
H7R73_RS19700	COG3409	Peptidoglycan-binding domain 1 protein
H7R73_RS19710	COG1194	a g-specific adenine glycosylase
H7R73_RS19715	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
H7R73_RS19730	COG3240	lipase activity
H7R73_RS19740	COG3009	Protein conserved in bacteria
H7R73_RS19745	COG3008	intermembrane lipid transfer
H7R73_RS19745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H7R73_RS19750	COG2995	paraquat-inducible protein a
H7R73_RS19760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R73_RS19765	COG3706	GGDEF domain
H7R73_RS19765	COG2203	Gaf domain
H7R73_RS19765	COG5001	Diguanylate cyclase
H7R73_RS19765	COG4251	negative regulation of phosphorylation
H7R73_RS19770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7R73_RS19775	COG2813	Specifically methylates the guanine in position
H7R73_RS19785	COG3385	transposase activity
H7R73_RS19795	COG0297	glycogen (starch) synthase activity
H7R73_RS19835	COG1757	Na H antiporter
H7R73_RS19840	COG0583	DNA-binding transcription factor activity
H7R73_RS19845	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H7R73_RS19850	COG3842	ATPase activity
H7R73_RS19855	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7R73_RS19860	COG1177	transmembrane transport
H7R73_RS19865	COG1012	belongs to the aldehyde dehydrogenase family
H7R73_RS19870	COG0109	protoheme IX farnesyltransferase activity
H7R73_RS19900	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
H7R73_RS19910	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7R73_RS19910	COG1565	acr, cog1565
H7R73_RS19915	COG1444	tRNA N-acetyltransferase activity
H7R73_RS19935	COG1803	Methylglyoxal synthase
H7R73_RS19950	COG0252	asparaginase activity
H7R73_RS19970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R73_RS19970	COG1263	PTS System
H7R73_RS19975	COG0366	Alpha amylase catalytic
H7R73_RS19980	COG0110	maltose O-acetyltransferase activity
H7R73_RS19985	COG1522	sequence-specific DNA binding
H7R73_RS20085	COG2314	TM2 domain
H7R73_RS20125	COG3422	double-strand break repair
H7R73_RS20155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H7R73_RS20160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H7R73_RS20175	COG0477	Major facilitator Superfamily
H7R73_RS20180	COG0523	cobalamin synthesis protein
H7R73_RS20190	COG1280	lysine exporter protein (LysE YggA)
H7R73_RS20200	COG2200	EAL domain
H7R73_RS20205	COG1049	propionate catabolic process, 2-methylcitrate cycle
H7R73_RS20210	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7R73_RS20215	COG0840	transmembrane signaling receptor activity
H7R73_RS20220	COG0840	transmembrane signaling receptor activity
H7R73_RS20230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7R73_RS20235	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7R73_RS20240	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H7R73_RS20245	COG2186	Transcriptional regulator
H7R73_RS20270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7R73_RS20275	COG1459	type II secretion system
H7R73_RS20280	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H7R73_RS20290	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
H7R73_RS20295	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H7R73_RS20300	COG0494	nUDIX hydrolase
H7R73_RS20310	COG0653	protein targeting
H7R73_RS20320	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H7R73_RS20325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H7R73_RS20330	COG0849	cell division
H7R73_RS20335	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H7R73_RS20340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7R73_RS20345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7R73_RS20350	COG0772	Belongs to the SEDS family
H7R73_RS20355	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7R73_RS20360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7R73_RS20365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7R73_RS20370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7R73_RS20375	COG0768	penicillin binding
H7R73_RS20380	COG3116	cell division
H7R73_RS20385	COG0275	rRNA processing
H7R73_RS20390	COG2001	Belongs to the MraZ family
H7R73_RS20400	COG0741	lytic transglycosylase activity
H7R73_RS20400	COG1388	LysM domain
H7R73_RS20410	COG1360	Flagellar Motor Protein
H7R73_RS20415	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7R73_RS20420	COG1191	sigma factor activity
H7R73_RS20445	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H7R73_RS20450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7R73_RS20455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7R73_RS20470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7R73_RS20475	COG4786	Flagellar basal body rod
H7R73_RS20475	COG1256	bacterial-type flagellum assembly
H7R73_RS20485	COG1706	bacterial-type flagellum-dependent cell motility
H7R73_RS20490	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H7R73_RS20495	COG4786	Flagellar basal body rod
H7R73_RS20505	COG1749	Flagellar hook protein flgE
H7R73_RS20520	COG1815	bacterial-type flagellum-dependent cell motility
H7R73_RS20525	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
H7R73_RS20555	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7R73_RS20565	COG1677	Flagellar hook-basal body complex protein FliE
H7R73_RS20590	COG1987	bacterial-type flagellum assembly
H7R73_RS20615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H7R73_RS20620	COG3107	peptidoglycan biosynthetic process
H7R73_RS20625	COG0792	nuclease activity
H7R73_RS20630	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H7R73_RS20635	COG2823	Periplasmic or secreted lipoprotein
H7R73_RS20640	COG2969	positive regulation of protein catabolic process
H7R73_RS20645	COG0625	glutathione transferase activity
H7R73_RS20650	COG2857	Cytochrome c1
H7R73_RS20655	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7R73_RS20660	COG0723	plastoquinol--plastocyanin reductase activity
H7R73_RS20665	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H7R73_RS20670	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H7R73_RS20675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H7R73_RS20685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7R73_RS20690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7R73_RS20720	COG3964	amidohydrolase
H7R73_RS20740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R73_RS20745	COG1660	Displays ATPase and GTPase activities
H7R73_RS20750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R73_RS20760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H7R73_RS20765	COG1137	ATPase activity
H7R73_RS20770	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H7R73_RS20780	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H7R73_RS20785	COG0517	IMP dehydrogenase activity
H7R73_RS20785	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H7R73_RS20790	COG1127	ABC transporter
H7R73_RS20795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H7R73_RS20800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H7R73_RS20805	COG2854	intermembrane phospholipid transfer
H7R73_RS20815	COG5007	Belongs to the BolA IbaG family
H7R73_RS20820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7R73_RS20825	COG0312	modulator of DNA gyrase
H7R73_RS20830	COG3028	Belongs to the UPF0307 family
H7R73_RS20840	COG2926	Belongs to the UPF0265 family
H7R73_RS20870	COG1396	sequence-specific DNA binding
H7R73_RS20875	COG3135	benzoate transporter
H7R73_RS20905	COG3047	cAMP biosynthetic process
H7R73_RS20915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H7R73_RS20920	COG2197	response regulator
H7R73_RS20940	COG1278	Cold shock
H7R73_RS20970	COG3706	GGDEF domain
H7R73_RS20975	COG0347	Belongs to the P(II) protein family
H7R73_RS20980	COG0004	ammonium transporteR
H7R73_RS20995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7R73_RS21000	COG1074	ATP-dependent DNA helicase activity
H7R73_RS21005	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H7R73_RS21010	COG2259	Doxx family
H7R73_RS21015	COG1741	Belongs to the pirin family
H7R73_RS21025	COG0583	DNA-binding transcription factor activity
H7R73_RS21050	COG1175	transmembrane transport
H7R73_RS21060	COG3842	ATPase activity
H7R73_RS21090	COG0456	acetyltransferase
H7R73_RS21095	COG0753	catalase activity
H7R73_RS21115	COG0494	nUDIX hydrolase
H7R73_RS21120	COG0628	permease
H7R73_RS21130	COG2957	Belongs to the agmatine deiminase family
H7R73_RS21145	COG2957	Belongs to the agmatine deiminase family
H7R73_RS21150	COG0583	DNA-binding transcription factor activity
H7R73_RS21165	COG1461	Dihydroxyacetone kinase
H7R73_RS21170	COG2376	Dihydroxyacetone kinase
H7R73_RS21175	COG2252	PERMEase
H7R73_RS21180	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H7R73_RS21210	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H7R73_RS21215	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7R73_RS21220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7R73_RS21225	COG0049	tRNA binding
H7R73_RS21230	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H7R73_RS21235	COG2168	tRNA wobble position uridine thiolation
H7R73_RS21245	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H7R73_RS21250	COG0251	oxidation-reduction process
H7R73_RS21255	COG2964	Protein conserved in bacteria
H7R73_RS21260	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H7R73_RS21265	COG0085	RNA polymerase activity
H7R73_RS21270	COG0222	ribosome binding
H7R73_RS21275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H7R73_RS21280	COG0081	regulation of translation
H7R73_RS21285	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H7R73_RS21290	COG0250	Participates in transcription elongation, termination and antitermination
H7R73_RS21305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7R73_RS21330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H7R73_RS21335	COG0569	domain protein
H7R73_RS21340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7R73_RS21345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7R73_RS21350	COG3005	denitrification pathway
H7R73_RS21355	COG0243	molybdopterin cofactor binding
H7R73_RS21390	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7R73_RS21400	COG2204	response regulator
H7R73_RS21410	COG2205	protein histidine kinase activity
H7R73_RS21430	COG4109	DRTGG domain
H7R73_RS21440	COG1522	sequence-specific DNA binding
H7R73_RS21445	COG2502	aspartate--ammonia ligase
H7R73_RS21450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7R73_RS21455	COG0542	response to heat
H7R73_RS21465	COG0564	pseudouridine synthase activity
H7R73_RS21470	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7R73_RS21475	COG3681	Belongs to the UPF0597 family
H7R73_RS21480	COG2964	Protein conserved in bacteria
H7R73_RS21485	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H7R73_RS21490	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H7R73_RS21495	COG1979	alcohol dehydrogenase
H7R73_RS21500	COG2207	Transcriptional regulator
H7R73_RS21505	COG3040	lipid binding
H7R73_RS21525	COG0583	DNA-binding transcription factor activity
H7R73_RS21545	COG0540	Belongs to the ATCase OTCase family
H7R73_RS21550	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
H7R73_RS21555	COG1438	arginine binding
H7R73_RS21560	COG1288	antiporter activity
H7R73_RS21565	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7R73_RS21605	COG3250	beta-galactosidase activity
H7R73_RS21610	COG1609	Transcriptional regulator
H7R73_RS21615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7R73_RS21625	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H7R73_RS21630	COG2017	converts alpha-aldose to the beta-anomer
H7R73_RS21635	COG0667	Aldo Keto reductase
H7R73_RS21640	COG1968	undecaprenyl-diphosphatase activity
H7R73_RS21645	COG3806	Anti-sigma factor
H7R73_RS21650	COG1595	DNA-templated transcription, initiation
H7R73_RS21670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H7R73_RS21675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H7R73_RS21680	COG0477	Major facilitator Superfamily
H7R73_RS21695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R73_RS21700	COG1131	(ABC) transporter
H7R73_RS21705	COG0842	Transport permease protein
H7R73_RS21710	COG0842	Transport permease protein
H7R73_RS21715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R73_RS21725	COG2116	formate transmembrane transporter activity
H7R73_RS21730	COG1648	precorrin-2 dehydrogenase activity
H7R73_RS21730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7R73_RS21735	COG2239	Acts as a magnesium transporter
H7R73_RS21740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7R73_RS21745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H7R73_RS21755	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H7R73_RS21765	COG0514	ATP-dependent DNA helicase (RecQ)
H7R73_RS21770	COG2050	protein possibly involved in aromatic compounds catabolism
H7R73_RS21785	COG2258	MOSC domain
H7R73_RS21790	COG1177	transmembrane transport
H7R73_RS21795	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7R73_RS21800	COG3842	ATPase activity
H7R73_RS21820	COG0174	glutamine synthetase
H7R73_RS21840	COG3045	CreA protein
H7R73_RS21845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7R73_RS21850	COG0443	Heat shock 70 kDa protein
H7R73_RS21865	COG0366	Alpha amylase catalytic
H7R73_RS21880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7R73_RS21885	COG0745	RESPONSE REGULATOR receiver
H7R73_RS21895	COG2205	protein histidine kinase activity
H7R73_RS21905	COG0281	malic enzyme
H7R73_RS21910	COG0702	epimerase
H7R73_RS21915	COG0254	rRNA binding
H7R73_RS21920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7R73_RS21925	COG1309	transcriptional regulator
H7R73_RS21945	COG0129	dihydroxy-acid dehydratase activity
H7R73_RS21955	COG3978	acetolactate synthase activity
H7R73_RS21965	COG0606	chelatase, subunit chli
H7R73_RS21970	COG0204	Acyl-transferase
H7R73_RS21975	COG0204	Acyl-transferase
H7R73_RS21980	COG1683	Conserved Protein
H7R73_RS21990	COG1335	isochorismatase
H7R73_RS22000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7R73_RS22005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7R73_RS22015	COG3084	Protein conserved in bacteria
H7R73_RS22020	COG5001	Diguanylate cyclase
H7R73_RS22020	COG2203	Gaf domain
H7R73_RS22020	COG4251	negative regulation of phosphorylation
H7R73_RS22020	COG3706	GGDEF domain
H7R73_RS22035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H7R73_RS22040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H7R73_RS22045	COG1561	YicC-like family, N-terminal region
H7R73_RS22055	COG1519	Transferase
H7R73_RS22060	COG0859	PFAM glycosyl transferase family 9
H7R73_RS22065	COG0463	Glycosyl transferase, family 2
H7R73_RS22070	COG0859	PFAM glycosyl transferase family 9
H7R73_RS22075	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H7R73_RS22080	COG2990	Protein conserved in bacteria
H7R73_RS22085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H7R73_RS22095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7R73_RS22100	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H7R73_RS22105	COG2003	Belongs to the UPF0758 family
H7R73_RS22110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7R73_RS22115	COG0756	dUTP diphosphatase activity
H7R73_RS22120	COG1309	transcriptional regulator
H7R73_RS22135	COG0668	transmembrane transport
H7R73_RS22145	COG0166	Belongs to the GPI family
H7R73_RS22150	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H7R73_RS22155	COG0583	DNA-binding transcription factor activity
H7R73_RS22165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7R73_RS22165	COG0045	succinate-CoA ligase (ADP-forming) activity
H7R73_RS22165	COG1042	CoA-binding domain protein
H7R73_RS22190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7R73_RS22195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7R73_RS22195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7R73_RS22200	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H7R73_RS22205	COG3074	FtsZ-dependent cytokinesis
H7R73_RS22215	COG1045	serine acetyltransferase
H7R73_RS22225	COG0745	RESPONSE REGULATOR receiver
H7R73_RS22230	COG2205	protein histidine kinase activity
H7R73_RS22235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7R73_RS22240	COG0534	Mate efflux family protein
H7R73_RS22255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7R73_RS22260	COG2937	Belongs to the GPAT DAPAT family
H7R73_RS22265	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H7R73_RS22270	COG3161	chorismate lyase activity
H7R73_RS22275	COG1580	Controls the rotational direction of flagella during chemotaxis
H7R73_RS22290	COG1609	Transcriptional regulator
H7R73_RS22325	COG3307	-O-antigen
H7R73_RS22335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7R73_RS22350	COG1063	alcohol dehydrogenase
H7R73_RS22370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7R73_RS22375	COG2166	iron-sulfur cluster assembly
H7R73_RS22380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7R73_RS22410	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
H7R73_RS22415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7R73_RS22420	COG1739	Uncharacterized protein family UPF0029
H7R73_RS22425	COG0006	proline dipeptidase activity
H7R73_RS22430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7R73_RS22435	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7R73_RS22435	COG1024	Enoyl-CoA hydratase
H7R73_RS22440	COG0183	Belongs to the thiolase family
H7R73_RS22470	COG0425	Belongs to the sulfur carrier protein TusA family
H7R73_RS22475	COG0251	oxidation-reduction process
H7R73_RS22495	COG2885	chlorophyll binding
H7R73_RS22505	COG1335	isochorismatase
H7R73_RS22510	COG2818	Glycosylase
H7R73_RS22515	COG0752	glycyl-tRNA synthetase alpha subunit
H7R73_RS22520	COG0751	glycine-tRNA ligase activity
H7R73_RS22530	COG3706	GGDEF domain
H7R73_RS22530	COG2203	Gaf domain
H7R73_RS22530	COG4251	negative regulation of phosphorylation
H7R73_RS22530	COG5001	Diguanylate cyclase
H7R73_RS22550	COG0814	amino acid
H7R73_RS22555	COG0814	amino acid
H7R73_RS22560	COG3033	Beta-eliminating lyase
H7R73_RS22585	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R73_RS22590	COG0426	domain, Protein
H7R73_RS22590	COG1773	rubredoxin
H7R73_RS22595	COG3604	Transcriptional regulator
H7R73_RS22600	COG1609	Transcriptional regulator
H7R73_RS22640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7R73_RS22655	COG2960	long-chain fatty acid transporting porin activity
H7R73_RS22665	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H7R73_RS22680	COG3118	belongs to the thioredoxin family
H7R73_RS22685	COG0513	Belongs to the DEAD box helicase family
H7R73_RS22690	COG0248	Ppx GppA phosphatase
H7R73_RS22700	COG0742	ribosomal rna small subunit methyltransferase
H7R73_RS22710	COG0339	signal peptide processing
H7R73_RS22720	COG0084	hydrolase, TatD family'
H7R73_RS22725	COG0805	protein transport
H7R73_RS22730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7R73_RS22735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7R73_RS22740	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H7R73_RS22745	COG3165	ubiquinone biosynthetic process from chorismate
H7R73_RS22755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7R73_RS22760	COG0402	S-adenosylhomocysteine deaminase activity
H7R73_RS22805	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
H7R73_RS22810	COG0848	biopolymer transport protein
H7R73_RS22815	COG0811	peptide transport
H7R73_RS22820	COG0811	peptide transport
H7R73_RS22830	COG2771	luxR family
H7R73_RS22835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7R73_RS22840	COG1349	DNA-binding transcription factor activity
H7R73_RS22845	COG0745	RESPONSE REGULATOR receiver
H7R73_RS22850	COG2205	protein histidine kinase activity
H7R73_RS22860	COG4452	Inner membrane protein CreD
H7R73_RS22865	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7R73_RS22870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H7R73_RS22875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H7R73_RS22880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H7R73_RS22885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H7R73_RS22890	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7R73_RS22895	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H7R73_RS22905	COG0356	it plays a direct role in the translocation of protons across the membrane
H7R73_RS22915	COG1475	DNA binding
H7R73_RS22920	COG1192	Involved in chromosome partitioning
H7R73_RS22925	COG0357	Ribosomal RNA small subunit methyltransferase G
H7R73_RS22930	COG0445	tRNA wobble uridine modification
H7R73_RS22935	COG0716	FMN binding
H7R73_RS22940	COG4774	siderophore transport
H7R73_RS22945	COG4615	Cyclic peptide transporter
H7R73_RS22950	COG1120	ATPase activity
H7R73_RS22955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7R73_RS22965	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H7R73_RS22970	COG0706	membrane insertase activity
H7R73_RS22975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7R73_RS22980	COG0594	ribonuclease P activity
H7R73_RS22985	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H7R73_RS22990	COG1126	abc transporter atp-binding protein
H7R73_RS23015	COG1192	Involved in chromosome partitioning
H7R73_RS23030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7R73_RS23055	COG1192	Involved in chromosome partitioning
H7R73_RS23160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7R73_RS23225	COG2176	DNA-directed DNA polymerase activity
H7R73_RS23225	COG5002	protein histidine kinase activity
H7R73_RS23240	COG0071	Belongs to the small heat shock protein (HSP20) family
H7R73_RS23245	COG0542	response to heat
H7R73_RS23295	COG1192	Involved in chromosome partitioning
H7R73_RS23325	COG2176	DNA-directed DNA polymerase activity
H7R73_RS23325	COG5002	protein histidine kinase activity
H7R73_RS23390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7R73_RS23395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7R73_RS23525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7R73_RS23700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7R73_RS23855	COG3041	Addiction module toxin RelE StbE family
H7R73_RS23860	COG3077	Addiction module antitoxin, RelB DinJ family
H7R73_RS23930	COG1846	Transcriptional regulator