locus-tag	class	description
B565_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B565_RS00010	COG0592	DNA-directed DNA polymerase activity
B565_RS00020	COG0187	DNA topoisomerase II activity
B565_RS00030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B565_RS00035	COG0071	Belongs to the small heat shock protein (HSP20) family
B565_RS00040	COG0071	Belongs to the small heat shock protein (HSP20) family
B565_RS00045	COG3977	Valine--pyruvate aminotransferase
B565_RS00060	COG2814	Major facilitator Superfamily
B565_RS00065	COG0745	RESPONSE REGULATOR receiver
B565_RS00070	COG2205	protein histidine kinase activity
B565_RS00090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B565_RS00095	COG4191	Histidine kinase
B565_RS00095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B565_RS00100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B565_RS00105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B565_RS00110	COG1309	transcriptional regulator
B565_RS00140	COG0561	phosphatase activity
B565_RS00145	COG2267	carboxylic ester hydrolase activity
B565_RS00155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B565_RS00160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B565_RS00165	COG1758	RNA polymerase activity
B565_RS00170	COG0194	GDP metabolic process
B565_RS00180	COG0859	PFAM glycosyl transferase family 9
B565_RS00185	COG3642	lipopolysaccharide core region biosynthetic process
B565_RS00220	COG0589	response to stress
B565_RS00225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B565_RS00230	COG1528	Iron-storage protein
B565_RS00235	COG2081	HI0933 family
B565_RS00240	COG3275	phosphorelay sensor kinase activity
B565_RS00245	COG3279	Response regulator of the LytR AlgR family
B565_RS00250	COG2223	nitrite transmembrane transporter activity
B565_RS00255	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B565_RS00260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B565_RS00275	COG0583	DNA-binding transcription factor activity
B565_RS00315	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B565_RS00320	COG2166	iron-sulfur cluster assembly
B565_RS00325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B565_RS00340	COG3245	cytochrome
B565_RS00345	COG1063	alcohol dehydrogenase
B565_RS00360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B565_RS00370	COG3307	-O-antigen
B565_RS00395	COG1280	lysine exporter protein (LysE YggA)
B565_RS00425	COG1943	Transposase
B565_RS00435	COG0210	DNA helicase
B565_RS00440	COG1744	ABC transporter substrate-binding protein PnrA-like
B565_RS00445	COG3845	ABC transporter
B565_RS00450	COG4603	Belongs to the binding-protein-dependent transport system permease family
B565_RS00455	COG1079	Belongs to the binding-protein-dependent transport system permease family
B565_RS00460	COG0737	Belongs to the 5'-nucleotidase family
B565_RS00470	COG2239	Acts as a magnesium transporter
B565_RS00475	COG1648	precorrin-2 dehydrogenase activity
B565_RS00475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B565_RS00480	COG2116	formate transmembrane transporter activity
B565_RS00490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B565_RS00495	COG0842	Transport permease protein
B565_RS00500	COG0842	Transport permease protein
B565_RS00505	COG1131	(ABC) transporter
B565_RS00510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B565_RS00520	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B565_RS00525	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B565_RS00535	COG0018	arginyl-trna synthetase
B565_RS00545	COG1595	DNA-templated transcription, initiation
B565_RS00555	COG1968	undecaprenyl-diphosphatase activity
B565_RS00560	COG2017	converts alpha-aldose to the beta-anomer
B565_RS00565	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B565_RS00570	COG1085	galactose-1-phosphate uridylyltransferase
B565_RS00575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B565_RS00580	COG1609	Transcriptional regulator
B565_RS00585	COG3250	beta-galactosidase activity
B565_RS00595	COG1129	ABC transporter
B565_RS00600	COG4211	Belongs to the binding-protein-dependent transport system permease family
B565_RS00610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B565_RS00625	COG0366	Alpha amylase catalytic
B565_RS00640	COG0443	Heat shock 70 kDa protein
B565_RS00645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B565_RS00650	COG3045	CreA protein
B565_RS00670	COG0174	glutamine synthetase
B565_RS00690	COG3842	ATPase activity
B565_RS00695	COG1176	ABC-type spermidine putrescine transport system, permease component I
B565_RS00700	COG1177	transmembrane transport
B565_RS00705	COG2258	MOSC domain
B565_RS00720	COG2050	protein possibly involved in aromatic compounds catabolism
B565_RS00725	COG0514	ATP-dependent DNA helicase (RecQ)
B565_RS00735	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B565_RS00745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B565_RS00750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B565_RS00765	COG0254	rRNA binding
B565_RS00770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B565_RS00780	COG0702	epimerase
B565_RS00785	COG0814	amino acid
B565_RS00790	COG0281	malic enzyme
B565_RS00795	COG1295	ribonuclease BN
B565_RS00800	COG1490	D-aminoacyl-tRNA deacylase activity
B565_RS00805	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B565_RS00810	COG0456	acetyltransferase
B565_RS00820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B565_RS00825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B565_RS00830	COG2610	gluconate transmembrane transporter activity
B565_RS00835	COG3265	gluconokinase activity
B565_RS00845	COG0800	Aldolase
B565_RS00850	COG1609	Transcriptional regulator
B565_RS00860	COG4942	peptidase
B565_RS00865	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B565_RS00870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B565_RS00875	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B565_RS00880	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B565_RS00885	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B565_RS00885	COG0316	Belongs to the HesB IscA family
B565_RS00890	COG1040	competence protein
B565_RS00895	COG0596	Alpha beta hydrolase
B565_RS00915	COG2183	response to ionizing radiation
B565_RS00920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B565_RS00940	COG0051	transcription antitermination factor activity, RNA binding
B565_RS00945	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B565_RS00950	COG0088	Forms part of the polypeptide exit tunnel
B565_RS00955	COG0089	rRNA binding
B565_RS00960	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B565_RS00965	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B565_RS00970	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B565_RS00975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B565_RS00980	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B565_RS00985	COG0255	Belongs to the universal ribosomal protein uL29 family
B565_RS00990	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B565_RS00995	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B565_RS01000	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B565_RS01005	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B565_RS01010	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B565_RS01015	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B565_RS01020	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B565_RS01025	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B565_RS01030	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B565_RS01035	COG1841	ribosomal large subunit assembly
B565_RS01040	COG0200	Binds to the 23S rRNA
B565_RS01045	COG0201	protein transport
B565_RS01050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B565_RS01055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B565_RS01060	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B565_RS01065	COG0202	RNA polymerase activity
B565_RS01070	COG0203	ribosomal protein L17
B565_RS01105	COG4771	TonB-dependent receptor
B565_RS01110	COG3706	GGDEF domain
B565_RS01135	COG0583	DNA-binding transcription factor activity
B565_RS01145	COG1741	Belongs to the pirin family
B565_RS01150	COG2259	Doxx family
B565_RS01155	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B565_RS01160	COG1074	ATP-dependent DNA helicase activity
B565_RS01165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B565_RS01210	COG1175	transmembrane transport
B565_RS01220	COG3842	ATPase activity
B565_RS01250	COG2873	o-acetylhomoserine
B565_RS01255	COG4533	DNA binding
B565_RS01275	COG5380	lipid catabolic process
B565_RS01280	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B565_RS01285	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B565_RS01310	COG0753	catalase activity
B565_RS01340	COG2927	DNA polymerase III (CHI subunit)
B565_RS01345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B565_RS01350	COG0795	lipopolysaccharide-transporting ATPase activity
B565_RS01355	COG0795	lipopolysaccharide-transporting ATPase activity
B565_RS01410	COG1494	fructose-1,6-bisphosphatase
B565_RS01425	COG2959	enzyme of heme biosynthesis
B565_RS01435	COG0181	hydroxymethylbilane synthase activity
B565_RS01440	COG3072	Adenylate cyclase
B565_RS01445	COG0400	carboxylic ester hydrolase activity
B565_RS01450	COG1965	Belongs to the frataxin family
B565_RS01455	COG0019	diaminopimelate decarboxylase activity
B565_RS01460	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B565_RS01475	COG1011	Hydrolase
B565_RS01495	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B565_RS01500	COG3028	Belongs to the UPF0307 family
B565_RS01505	COG0312	modulator of DNA gyrase
B565_RS01510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B565_RS01515	COG5007	Belongs to the BolA IbaG family
B565_RS01525	COG2854	intermembrane phospholipid transfer
B565_RS01530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B565_RS01535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B565_RS01540	COG1127	ABC transporter
B565_RS01545	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B565_RS01545	COG0517	IMP dehydrogenase activity
B565_RS01550	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B565_RS01555	COG3117	lipopolysaccharide transmembrane transporter activity
B565_RS01560	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B565_RS01565	COG1137	ATPase activity
B565_RS01580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS01585	COG1660	Displays ATPase and GTPase activities
B565_RS01590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS01595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS01595	COG3711	transcriptional antiterminator
B565_RS01610	COG3964	amidohydrolase
B565_RS01640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B565_RS01645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B565_RS01655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B565_RS01660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B565_RS01665	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B565_RS01670	COG0723	plastoquinol--plastocyanin reductase activity
B565_RS01675	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B565_RS01680	COG2857	Cytochrome c1
B565_RS01685	COG0625	glutathione transferase activity
B565_RS01690	COG2969	positive regulation of protein catabolic process
B565_RS01695	COG2823	Periplasmic or secreted lipoprotein
B565_RS01700	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B565_RS01705	COG0792	nuclease activity
B565_RS01710	COG3107	peptidoglycan biosynthetic process
B565_RS01715	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B565_RS01720	COG2001	Belongs to the MraZ family
B565_RS01725	COG0275	rRNA processing
B565_RS01730	COG3116	cell division
B565_RS01735	COG0768	penicillin binding
B565_RS01745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B565_RS01750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B565_RS01755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B565_RS01760	COG0772	Belongs to the SEDS family
B565_RS01765	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B565_RS01770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B565_RS01780	COG0849	cell division
B565_RS01785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B565_RS01790	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B565_RS01800	COG0653	protein targeting
B565_RS01805	COG0494	nUDIX hydrolase
B565_RS01810	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
B565_RS01815	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
B565_RS01830	COG1459	type II secretion system
B565_RS01835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B565_RS01860	COG2186	Transcriptional regulator
B565_RS01865	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B565_RS01870	COG0508	dehydrogenase complex catalyzes the overall conversion of
B565_RS01875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B565_RS01885	COG0840	transmembrane signaling receptor activity
B565_RS01890	COG1752	Esterase of the alpha-beta hydrolase superfamily
B565_RS01895	COG1049	propionate catabolic process, 2-methylcitrate cycle
B565_RS01900	COG2200	EAL domain
B565_RS01910	COG0523	cobalamin synthesis protein
B565_RS01915	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B565_RS01930	COG0477	Major facilitator Superfamily
B565_RS01945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B565_RS01950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B565_RS01975	COG3314	Sporulation integral membrane protein YlbJ
B565_RS01990	COG0165	Argininosuccinate lyase
B565_RS01995	COG0137	argininosuccinate synthase activity
B565_RS02005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B565_RS02010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B565_RS02020	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B565_RS02030	COG3706	GGDEF domain
B565_RS02035	COG0814	amino acid
B565_RS02040	COG3932	Exopolysaccharide synthesis, ExoD
B565_RS02055	COG0004	ammonium transporteR
B565_RS02060	COG3133	Outer membrane lipoprotein
B565_RS02065	COG0456	acetyltransferase
B565_RS02085	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B565_RS02090	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B565_RS02105	COG0494	nUDIX hydrolase
B565_RS02110	COG0628	permease
B565_RS02130	COG3284	Transcriptional regulator
B565_RS02140	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
B565_RS02140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS02140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B565_RS02145	COG1461	Dihydroxyacetone kinase
B565_RS02150	COG2376	Dihydroxyacetone kinase
B565_RS02155	COG2252	PERMEase
B565_RS02160	COG1278	Cold shock
B565_RS02170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B565_RS02185	COG2197	response regulator
B565_RS02220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B565_RS02225	COG2199	diguanylate cyclase activity
B565_RS02230	COG3047	cAMP biosynthetic process
B565_RS02235	COG0840	transmembrane signaling receptor activity
B565_RS02260	COG3135	benzoate transporter
B565_RS02265	COG1396	sequence-specific DNA binding
B565_RS02305	COG2926	Belongs to the UPF0265 family
B565_RS02315	COG0561	phosphatase activity
B565_RS02325	COG1058	Belongs to the CinA family
B565_RS02325	COG1546	Belongs to the CinA family
B565_RS02335	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B565_RS02345	COG1522	sequence-specific DNA binding
B565_RS02350	COG1368	sulfuric ester hydrolase activity
B565_RS02385	COG4221	oxidoreductase activity
B565_RS02400	COG1979	alcohol dehydrogenase
B565_RS02405	COG1803	Methylglyoxal synthase
B565_RS02430	COG1028	Short-chain dehydrogenase reductase Sdr
B565_RS02435	COG0835	chemotaxis
B565_RS02435	COG0784	Response regulator, receiver
B565_RS02445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B565_RS02450	COG2949	membrane
B565_RS02455	COG3291	Pkd domain containing protein
B565_RS02465	COG3539	Fimbrial protein
B565_RS02475	COG3188	usher protein
B565_RS02480	COG3121	Chaperone
B565_RS02485	COG3539	Fimbrial protein
B565_RS02500	COG0318	PFAM AMP-dependent synthetase and ligase
B565_RS02505	COG1441	menaquinone biosynthetic process
B565_RS02510	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B565_RS02515	COG0596	Alpha beta hydrolase
B565_RS02520	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B565_RS02525	COG1169	isochorismate synthase
B565_RS02530	COG1575	Belongs to the MenA family. Type 1 subfamily
B565_RS02555	COG0513	Belongs to the DEAD box helicase family
B565_RS02560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B565_RS02565	COG1988	membrane-bound metal-dependent
B565_RS02570	COG1671	Belongs to the UPF0178 family
B565_RS02590	COG0484	heat shock protein binding
B565_RS02600	COG3722	fumarate hydratase activity
B565_RS02605	COG0246	Mannitol dehydrogenase
B565_RS02610	COG2213	PTS system mannitol-specific
B565_RS02610	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS02615	COG1560	Kdo2-lipid A biosynthetic process
B565_RS02620	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B565_RS02620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B565_RS02625	COG1538	Outer membrane efflux protein
B565_RS02630	COG0494	nUDIX hydrolase
B565_RS02635	COG3151	Protein conserved in bacteria
B565_RS02645	COG3150	esterase
B565_RS02660	COG0583	DNA-binding transcription factor activity
B565_RS02670	COG3104	oligopeptide transport
B565_RS02700	COG2084	Dehydrogenase
B565_RS02710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B565_RS02730	COG0204	Acyl-transferase
B565_RS02735	COG1842	Phage shock protein A
B565_RS02750	COG2827	Endonuclease containing a URI domain
B565_RS02765	COG1573	uracil-dna glycosylase
B565_RS02770	COG0697	spore germination
B565_RS02775	COG0583	DNA-binding transcription factor activity
B565_RS02780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B565_RS02785	COG1121	(ABC) transporter
B565_RS02790	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
B565_RS02810	COG0739	heme binding
B565_RS02820	COG3068	Protein conserved in bacteria
B565_RS02840	COG0617	tRNA 3'-terminal CCA addition
B565_RS02845	COG1194	a g-specific adenine glycosylase
B565_RS02850	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
B565_RS02860	COG3111	PFAM Bacterial OB fold (BOF) protein
B565_RS02865	COG3240	lipase activity
B565_RS02870	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B565_RS02870	COG2885	chlorophyll binding
B565_RS02875	COG3706	GGDEF domain
B565_RS02880	COG0557	exoribonuclease II activity
B565_RS02885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B565_RS02895	COG2153	protein acetylation
B565_RS02900	COG0513	Belongs to the DEAD box helicase family
B565_RS02905	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B565_RS02935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B565_RS02940	COG0840	transmembrane signaling receptor activity
B565_RS02950	COG4166	transmembrane transport
B565_RS02960	COG0110	maltose O-acetyltransferase activity
B565_RS02970	COG1024	Enoyl-CoA hydratase
B565_RS02985	COG4221	oxidoreductase activity
B565_RS02990	COG0442	prolyl-tRNA aminoacylation
B565_RS02995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B565_RS03005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B565_RS03005	COG3008	intermembrane lipid transfer
B565_RS03010	COG2995	paraquat-inducible protein a
B565_RS03020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B565_RS03030	COG5001	Diguanylate cyclase
B565_RS03030	COG4251	negative regulation of phosphorylation
B565_RS03030	COG3706	GGDEF domain
B565_RS03030	COG2203	Gaf domain
B565_RS03035	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
B565_RS03050	COG2771	luxR family
B565_RS03060	COG0840	transmembrane signaling receptor activity
B565_RS03065	COG0632	four-way junction helicase activity
B565_RS03070	COG2255	four-way junction helicase activity
B565_RS03080	COG1294	oxidase, subunit
B565_RS03090	COG3790	cyd operon protein YbgE
B565_RS03095	COG0824	Thioesterase
B565_RS03100	COG0811	peptide transport
B565_RS03115	COG0823	Involved in the tonB-independent uptake of proteins
B565_RS03120	COG2885	chlorophyll binding
B565_RS03125	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
B565_RS03140	COG0733	neurotransmitter:sodium symporter activity
B565_RS03150	COG0733	neurotransmitter:sodium symporter activity
B565_RS03165	COG0561	phosphatase activity
B565_RS03215	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B565_RS03220	COG1640	4-alpha-glucanotransferase
B565_RS03225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B565_RS03235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B565_RS03240	COG0840	transmembrane signaling receptor activity
B565_RS03245	COG1585	Membrane protein implicated in regulation of membrane protease activity
B565_RS03250	COG0330	HflC and HflK could
B565_RS03255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B565_RS03255	COG1648	precorrin-2 dehydrogenase activity
B565_RS03260	COG0175	sulfate reduction
B565_RS03265	COG2895	sulfate adenylyltransferase (ATP) activity
B565_RS03270	COG3273	potassium ion transport
B565_RS03270	COG0471	metal ion transport
B565_RS03275	COG0529	Catalyzes the synthesis of activated sulfate
B565_RS03285	COG0840	transmembrane signaling receptor activity
B565_RS03305	COG1136	(ABC) transporter
B565_RS03320	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
B565_RS03335	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B565_RS03340	COG0784	Response regulator, receiver
B565_RS03340	COG3437	response regulator, receiver
B565_RS03350	COG2076	Multidrug Resistance protein
B565_RS03355	COG2076	Multidrug Resistance protein
B565_RS03360	COG0346	lactoylglutathione lyase activity
B565_RS03365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B565_RS03370	COG1643	Atp-dependent helicase
B565_RS03380	COG1489	DNA binding
B565_RS03385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B565_RS03390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B565_RS03400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B565_RS03405	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B565_RS03410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B565_RS03420	COG1823	symporter activity
B565_RS03445	COG0842	Transport permease protein
B565_RS03450	COG1131	(ABC) transporter
B565_RS03465	COG0163	prenyltransferase activity
B565_RS03470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B565_RS03475	COG0671	phosphoesterase, PA-phosphatase related
B565_RS03480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B565_RS03490	COG1151	hydroxylamine reductase activity
B565_RS03495	COG0783	Belongs to the Dps family
B565_RS03500	COG3023	N-Acetylmuramoyl-L-alanine amidase
B565_RS03505	COG4807	Protein conserved in bacteria
B565_RS03515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B565_RS03520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B565_RS03525	COG3956	TIGRFAM MazG family protein
B565_RS03530	COG0504	CTP synthase activity
B565_RS03535	COG0148	phosphopyruvate hydratase activity
B565_RS03580	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B565_RS03590	COG0488	(ABC) transporter
B565_RS03610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B565_RS03625	COG1794	racemase activity, acting on amino acids and derivatives
B565_RS03635	COG2731	YhcH YjgK YiaL family protein
B565_RS03645	COG0668	transmembrane transport
B565_RS03650	COG1376	ErfK ybiS ycfS ynhG family protein
B565_RS03660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B565_RS03665	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B565_RS03670	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B565_RS03680	COG0585	pseudouridine synthase activity
B565_RS03685	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B565_RS03690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B565_RS03695	COG1238	metal cluster binding
B565_RS03710	COG1902	pentaerythritol trinitrate reductase activity
B565_RS03725	COG2957	Belongs to the agmatine deiminase family
B565_RS03730	COG0154	amidase activity
B565_RS03745	COG0513	Belongs to the DEAD box helicase family
B565_RS03750	COG2203	Gaf domain
B565_RS03750	COG2199	diguanylate cyclase activity
B565_RS03760	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
B565_RS03765	COG1858	cytochrome C peroxidase
B565_RS03810	COG2816	NAD+ diphosphatase activity
B565_RS03820	COG4191	Histidine kinase
B565_RS03845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B565_RS03860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B565_RS03865	COG4991	sh3 domain protein
B565_RS03875	COG2816	NAD+ diphosphatase activity
B565_RS03880	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B565_RS03885	COG1940	carbohydrate kinase activity
B565_RS03890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B565_RS03895	COG0126	phosphoglycerate kinase activity
B565_RS03900	COG0191	fructose-bisphosphate aldolase activity
B565_RS03905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B565_RS03950	COG0354	folic acid binding
B565_RS03955	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B565_RS03965	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B565_RS03970	COG1595	DNA-templated transcription, initiation
B565_RS03975	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
B565_RS03980	COG3026	antisigma factor binding
B565_RS03990	COG0481	GTPase activity
B565_RS03995	COG0681	Belongs to the peptidase S26 family
B565_RS04010	COG1381	Involved in DNA repair and RecF pathway recombination
B565_RS04015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B565_RS04025	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B565_RS04030	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS04035	COG3716	PTS system mannose fructose sorbose family IID component
B565_RS04045	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B565_RS04050	COG2222	sugar isomerase
B565_RS04060	COG1349	DNA-binding transcription factor activity
B565_RS04070	COG2350	Protein conserved in bacteria
B565_RS04075	COG2917	probably involved in intracellular septation
B565_RS04080	COG0076	glutamate decarboxylase activity
B565_RS04085	COG1272	protein, Hemolysin III
B565_RS04090	COG2985	domain, Protein
B565_RS04090	COG0569	domain protein
B565_RS04110	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
B565_RS04135	COG2313	pseudouridylate synthase activity
B565_RS04140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B565_RS04180	COG1765	OsmC-like protein
B565_RS04195	COG3954	Phosphoribulokinase
B565_RS04200	COG3089	Belongs to the UPF0270 family
B565_RS04205	COG5001	Diguanylate cyclase
B565_RS04205	COG4251	negative regulation of phosphorylation
B565_RS04205	COG3706	GGDEF domain
B565_RS04205	COG2203	Gaf domain
B565_RS04210	COG0429	hydrolase of the alpha beta-hydrolase fold
B565_RS04215	COG0784	Response regulator, receiver
B565_RS04215	COG0835	chemotaxis
B565_RS04225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
B565_RS04230	COG1047	Peptidyl-prolyl cis-trans
B565_RS04250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B565_RS04275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B565_RS04285	COG3721	Heme iron utilization protein
B565_RS04290	COG0748	coenzyme F420 binding
B565_RS04315	COG2814	Major facilitator Superfamily
B565_RS04325	COG3655	Transcriptional regulator
B565_RS04335	COG5002	protein histidine kinase activity
B565_RS04335	COG2205	protein histidine kinase activity
B565_RS04335	COG0784	Response regulator, receiver
B565_RS04350	COG3706	GGDEF domain
B565_RS04365	COG3397	chitin binding
B565_RS04405	COG0835	chemotaxis
B565_RS04405	COG0784	Response regulator, receiver
B565_RS04410	COG2755	lipolytic protein G-D-S-L family
B565_RS04415	COG4181	ATPase activity
B565_RS04420	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B565_RS04425	COG1090	epimerase
B565_RS04430	COG2200	EAL domain
B565_RS04435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B565_RS04440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B565_RS04445	COG3171	Protein conserved in bacteria
B565_RS04450	COG2066	Belongs to the glutaminase family
B565_RS04455	COG2897	thiosulfate sulfurtransferase activity
B565_RS04470	COG0521	Mo-molybdopterin cofactor biosynthetic process
B565_RS04480	COG2966	Psort location CytoplasmicMembrane, score
B565_RS04485	COG3610	response to peptide
B565_RS04495	COG0175	sulfate reduction
B565_RS04500	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B565_RS04505	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B565_RS04515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B565_RS04520	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B565_RS04530	COG0786	glutamate:sodium symporter activity
B565_RS04535	COG0252	asparaginase activity
B565_RS04540	COG3139	Protein of unknown function (DUF1315)
B565_RS04560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B565_RS04565	COG0321	lipoyl(octanoyl) transferase activity
B565_RS04570	COG2921	Belongs to the UPF0250 family
B565_RS04575	COG1686	Belongs to the peptidase S11 family
B565_RS04580	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B565_RS04585	COG2951	lytic endotransglycosylase activity
B565_RS04590	COG0772	Belongs to the SEDS family
B565_RS04595	COG0768	penicillin binding
B565_RS04600	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B565_RS04605	COG0799	negative regulation of ribosome biogenesis
B565_RS04610	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B565_RS04625	COG0495	leucyl-tRNA aminoacylation
B565_RS04630	COG2888	peptidyl-tyrosine sulfation
B565_RS04635	COG0312	modulator of DNA gyrase
B565_RS04645	COG0716	FMN binding
B565_RS04650	COG4974	Belongs to the 'phage' integrase family
B565_RS04660	COG1970	mechanosensitive ion channel activity
B565_RS04680	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B565_RS04685	COG4535	Mg2 and Co2 transporter CorC
B565_RS04690	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B565_RS04695	COG1702	phosphate starvation-inducible protein PhoH
B565_RS04700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B565_RS04705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B565_RS04710	COG1335	isochorismatase
B565_RS04715	COG3706	GGDEF domain
B565_RS04720	COG0583	DNA-binding transcription factor activity
B565_RS04745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B565_RS04755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B565_RS04765	COG0516	GMP reductase activity
B565_RS04775	COG0642	Histidine kinase
B565_RS04790	COG4221	oxidoreductase activity
B565_RS04800	COG1022	Amp-dependent synthetase and ligase
B565_RS04815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B565_RS04830	COG3214	Protein conserved in bacteria
B565_RS04840	COG2195	Cleaves the N-terminal amino acid of tripeptides
B565_RS04845	COG0700	Nucleoside recognition
B565_RS04850	COG3366	ferrous iron transmembrane transporter activity
B565_RS04855	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
B565_RS04860	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
B565_RS04865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B565_RS04870	COG1053	succinate dehydrogenase
B565_RS04880	COG0584	glycerophosphoryl diester phosphodiesterase
B565_RS04885	COG3264	Mechanosensitive ion channel
B565_RS04885	COG1511	domain protein
B565_RS04895	COG0739	heme binding
B565_RS04905	COG0583	DNA-binding transcription factor activity
B565_RS04925	COG0583	DNA-binding transcription factor activity
B565_RS04930	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B565_RS04960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B565_RS04965	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B565_RS04975	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B565_RS04980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B565_RS04990	COG0180	Tryptophanyl-tRNA synthetase
B565_RS05000	COG0512	Glutamine amidotransferase of anthranilate synthase
B565_RS05005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B565_RS05015	COG1012	belongs to the aldehyde dehydrogenase family
B565_RS05030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B565_RS05040	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B565_RS05040	COG1013	pyruvate-flavodoxin oxidoreductase activity
B565_RS05040	COG0674	pyruvate-flavodoxin oxidoreductase activity
B565_RS05040	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B565_RS05045	COG0366	Alpha amylase catalytic
B565_RS05055	COG0657	acetylesterase activity
B565_RS05060	COG3097	Belongs to the UPF0267 family
B565_RS05070	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
B565_RS05080	COG0471	metal ion transport
B565_RS05080	COG0490	domain, Protein
B565_RS05115	COG0012	GTP binding
B565_RS05120	COG0193	aminoacyl-tRNA hydrolase activity
B565_RS05125	COG0737	Belongs to the 5'-nucleotidase family
B565_RS05130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B565_RS05140	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B565_RS05145	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B565_RS05150	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B565_RS05155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B565_RS05160	COG2890	protein-(glutamine-N5) methyltransferase activity
B565_RS05170	COG2912	Transglutaminase-like superfamily
B565_RS05175	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B565_RS05180	COG1301	dicarboxylic acid transport
B565_RS05195	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B565_RS05205	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
B565_RS05205	COG3408	Glycogen debranching enzyme
B565_RS05215	COG1881	PFAM PEBP family protein
B565_RS05220	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B565_RS05235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B565_RS05245	COG0583	DNA-binding transcription factor activity
B565_RS05250	COG1028	Short-chain dehydrogenase reductase Sdr
B565_RS05255	COG0616	signal peptide processing
B565_RS05260	COG2211	Major facilitator Superfamily
B565_RS05265	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B565_RS05275	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B565_RS05280	COG0826	peptidase U32
B565_RS05285	COG2200	EAL domain
B565_RS05285	COG2199	diguanylate cyclase activity
B565_RS05285	COG2203	Gaf domain
B565_RS05310	COG2197	response regulator
B565_RS05340	COG3724	N-succinylarginine dihydrolase activity
B565_RS05355	COG0840	transmembrane signaling receptor activity
B565_RS05365	COG2971	BadF BadG BcrA BcrD
B565_RS05375	COG4608	Belongs to the ABC transporter superfamily
B565_RS05380	COG0444	Belongs to the ABC transporter superfamily
B565_RS05385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B565_RS05400	COG0784	Response regulator, receiver
B565_RS05400	COG2205	protein histidine kinase activity
B565_RS05430	COG3220	belongs to the UPF0276 family
B565_RS05460	COG1289	transmembrane transporter activity
B565_RS05465	COG0303	'Molybdopterin
B565_RS05470	COG0746	molybdenum cofactor guanylyltransferase activity
B565_RS05480	COG4662	Binding-protein-dependent transport system inner membrane component
B565_RS05495	COG3852	Histidine kinase
B565_RS05505	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B565_RS05535	COG3383	formate dehydrogenase (NAD+) activity
B565_RS05535	COG3383	formate dehydrogenase (NAD+) activity
B565_RS05540	COG0437	4 iron, 4 sulfur cluster binding
B565_RS05560	COG0281	malic enzyme
B565_RS05580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B565_RS05610	COG0837	glucose binding
B565_RS05615	COG1737	Transcriptional regulator
B565_RS05620	COG0469	pyruvate kinase activity
B565_RS05640	COG1677	Flagellar hook-basal body complex protein FliE
B565_RS05650	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B565_RS05700	COG1987	bacterial-type flagellum assembly
B565_RS05705	COG1684	flagellar biosynthetic protein fliR
B565_RS05715	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B565_RS05740	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
B565_RS05745	COG0643	Histidine kinase
B565_RS05745	COG0784	Response regulator, receiver
B565_RS05745	COG2198	Histidine kinase
B565_RS05750	COG2201	protein-glutamate methylesterase activity
B565_RS05755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B565_RS05760	COG1360	Flagellar Motor Protein
B565_RS05765	COG1192	Involved in chromosome partitioning
B565_RS05775	COG0835	chemotaxis
B565_RS05790	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B565_RS05795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B565_RS05800	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B565_RS05805	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
B565_RS05810	COG1138	Cytochrome C-type biogenesis protein
B565_RS05815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B565_RS05820	COG4235	cytochrome complex assembly
B565_RS05820	COG3088	subunit of a heme lyase
B565_RS05830	COG2853	Lipoprotein
B565_RS05840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B565_RS05845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B565_RS05855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B565_RS05860	COG1882	Formate acetyltransferase
B565_RS05870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B565_RS05870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B565_RS05910	COG0259	pyridoxamine-phosphate oxidase activity
B565_RS05935	COG2850	peptidyl-arginine hydroxylation
B565_RS05940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B565_RS05945	COG2915	High frequency lysogenization protein hflD homolog
B565_RS05950	COG0482	sulfurtransferase activity
B565_RS05960	COG1187	pseudouridine synthase activity
B565_RS05970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B565_RS05975	COG2271	Major facilitator Superfamily
B565_RS05980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B565_RS05980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS05980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B565_RS06005	COG0783	Belongs to the Dps family
B565_RS06035	COG0456	acetyltransferase
B565_RS06050	COG1609	Transcriptional regulator
B565_RS06055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B565_RS06055	COG1263	PTS System
B565_RS06060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B565_RS06065	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B565_RS06075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B565_RS06080	COG1960	acyl-CoA dehydrogenase activity
B565_RS06090	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B565_RS06100	COG3383	formate dehydrogenase (NAD+) activity
B565_RS06110	COG2205	protein histidine kinase activity
B565_RS06110	COG0784	Response regulator, receiver
B565_RS06115	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B565_RS06120	COG2867	negative regulation of translational initiation
B565_RS06125	COG2914	Belongs to the UPF0125 (RnfH) family
B565_RS06130	COG1473	amidohydrolase
B565_RS06135	COG1960	acyl-CoA dehydrogenase activity
B565_RS06140	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B565_RS06145	COG0121	glutamine amidotransferase
B565_RS06175	COG2197	response regulator
B565_RS06180	COG3850	Histidine kinase
B565_RS06185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B565_RS06190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B565_RS06200	COG0243	molybdopterin cofactor binding
B565_RS06205	COG0437	4 iron, 4 sulfur cluster binding
B565_RS06210	COG0348	domain, Protein
B565_RS06220	COG3005	denitrification pathway
B565_RS06225	COG0521	Mo-molybdopterin cofactor biosynthetic process
B565_RS06230	COG0315	cyclic pyranopterin monophosphate synthase activity
B565_RS06235	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B565_RS06240	COG0314	molybdopterin synthase activity
B565_RS06255	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B565_RS06260	COG2267	carboxylic ester hydrolase activity
B565_RS06265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B565_RS06275	COG0302	gtp cyclohydrolase
B565_RS06280	COG0840	transmembrane signaling receptor activity
B565_RS06285	COG2759	Belongs to the formate--tetrahydrofolate ligase family
B565_RS06295	COG0583	DNA-binding transcription factor activity
B565_RS06300	COG2353	YceI-like domain
B565_RS06310	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B565_RS06325	COG2195	Cleaves the N-terminal amino acid of tripeptides
B565_RS06330	COG1166	arginine decarboxylase activity
B565_RS06340	COG2015	COG2015, Alkyl sulfatase and related hydrolases
B565_RS06360	COG0814	amino acid
B565_RS06370	COG3681	Belongs to the UPF0597 family
B565_RS06375	COG2964	Protein conserved in bacteria
B565_RS06385	COG2932	Transcriptional regulator
B565_RS06500	COG0640	Transcriptional regulator
B565_RS06510	COG4373	Mu-like prophage FluMu protein gp28
B565_RS06515	COG4383	Mu-like prophage protein gp29
B565_RS06530	COG4388	Caudovirus prohead serine protease
B565_RS06535	COG4397	Mu-like prophage major head subunit gpT
B565_RS06615	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B565_RS06620	COG1288	antiporter activity
B565_RS06625	COG1288	antiporter activity
B565_RS06630	COG0436	Aminotransferase
B565_RS06640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B565_RS06645	COG0739	heme binding
B565_RS06645	COG1196	nuclear chromosome segregation
B565_RS06645	COG0741	lytic transglycosylase activity
B565_RS06660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B565_RS06670	COG0788	formyltetrahydrofolate deformylase activity
B565_RS06675	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B565_RS06685	COG3118	belongs to the thioredoxin family
B565_RS06695	COG0791	NLP P60 protein
B565_RS06700	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
B565_RS06710	COG0471	metal ion transport
B565_RS06720	COG1388	LysM domain
B565_RS06720	COG1376	ErfK ybiS ycfS ynhG family protein
B565_RS06730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B565_RS06735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B565_RS06740	COG0745	RESPONSE REGULATOR receiver
B565_RS06745	COG5000	phosphorelay sensor kinase activity
B565_RS06745	COG5002	protein histidine kinase activity
B565_RS06770	COG1388	LysM domain
B565_RS06770	COG0741	lytic transglycosylase activity
B565_RS06775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B565_RS06780	COG2226	methyltransferase
B565_RS06785	COG0328	RNA-DNA hybrid ribonuclease activity
B565_RS06790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B565_RS06800	COG3437	response regulator, receiver
B565_RS06800	COG0784	Response regulator, receiver
B565_RS06805	COG2375	cellular response to nickel ion
B565_RS06810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B565_RS06815	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B565_RS06820	COG1120	ATPase activity
B565_RS06825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B565_RS06835	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B565_RS06840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B565_RS06875	COG0708	Exodeoxyribonuclease III
B565_RS06905	COG3132	Protein of unknown function, DUF480
B565_RS06910	COG3300	MHYT domain
B565_RS06910	COG5001	Diguanylate cyclase
B565_RS06920	COG2841	Protein conserved in bacteria
B565_RS06930	COG0534	Mate efflux family protein
B565_RS06960	COG1309	transcriptional regulator
B565_RS06995	COG3152	Membrane
B565_RS07010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B565_RS07025	COG2207	Transcriptional regulator
B565_RS07030	COG0538	isocitrate dehydrogenase activity
B565_RS07035	COG3048	D-serine ammonia-lyase activity
B565_RS07040	COG2610	gluconate transmembrane transporter activity
B565_RS07045	COG0583	DNA-binding transcription factor activity
B565_RS07050	COG0791	NLP P60 protein
B565_RS07055	COG0583	DNA-binding transcription factor activity
B565_RS07060	COG0450	alkyl hydroperoxide reductase
B565_RS07080	COG0500	methyltransferase
B565_RS07085	COG4106	trans-aconitate 2-methyltransferase activity
B565_RS07090	COG1801	Protein of unknown function DUF72
B565_RS07100	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B565_RS07105	COG0217	transcriptional regulatory protein
B565_RS07110	COG1454	alcohol dehydrogenase
B565_RS07110	COG1012	belongs to the aldehyde dehydrogenase family
B565_RS07115	COG2095	MarC family integral membrane protein
B565_RS07125	COG0601	transmembrane transport
B565_RS07130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B565_RS07145	COG0861	Integral membrane protein TerC family
B565_RS07150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B565_RS07180	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
B565_RS07190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B565_RS07195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B565_RS07200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B565_RS07205	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B565_RS07210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B565_RS07225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B565_RS07230	COG0505	Belongs to the CarA family
B565_RS07235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B565_RS07245	COG0287	Prephenate dehydrogenase
B565_RS07245	COG1605	Chorismate mutase
B565_RS07250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B565_RS07260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B565_RS07265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B565_RS07300	COG0537	adenosine 5'-monophosphoramidase activity
B565_RS07315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B565_RS07330	COG1301	dicarboxylic acid transport
B565_RS07350	COG2354	Protein conserved in bacteria
B565_RS07360	COG2233	PERMEase
B565_RS07365	COG3150	esterase
B565_RS07370	COG1252	NADH dehydrogenase
B565_RS07380	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B565_RS07385	COG5001	Diguanylate cyclase
B565_RS07385	COG3300	MHYT domain
B565_RS07390	COG0446	pyridine nucleotide-disulphide oxidoreductase
B565_RS07400	COG2373	Large extracellular alpha-helical protein
B565_RS07405	COG4953	penicillin-binding protein 1C
B565_RS07415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B565_RS07415	COG0301	tRNA thio-modification
B565_RS07430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B565_RS07435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B565_RS07440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B565_RS07445	COG1334	flagellar protein FlaG
B565_RS07495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B565_RS07510	COG0483	inositol monophosphate 1-phosphatase activity
B565_RS07520	COG0625	glutathione transferase activity
B565_RS07525	COG2814	Major facilitator Superfamily
B565_RS07540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B565_RS07545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B565_RS07555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B565_RS07560	COG0509	glycine decarboxylation via glycine cleavage system
B565_RS07565	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B565_RS07565	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B565_RS07570	COG0840	transmembrane signaling receptor activity
B565_RS07595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B565_RS07600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B565_RS07600	COG0574	Belongs to the PEP-utilizing enzyme family
B565_RS07625	COG1464	Belongs to the NlpA lipoprotein family
B565_RS07630	COG3083	sulfuric ester hydrolase activity
B565_RS07635	COG3082	Protein of unknown function (DUF1414)
B565_RS07640	COG3081	Nucleoid-associated protein
B565_RS07650	COG1175	transmembrane transport
B565_RS07655	COG3833	ABC-type maltose transport systems, permease component
B565_RS07660	COG3842	ATPase activity
B565_RS07690	COG4783	chaperone-mediated protein folding
B565_RS07700	COG1393	Belongs to the ArsC family
B565_RS07710	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
B565_RS07715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B565_RS07720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B565_RS07725	COG2431	L-lysine efflux transmembrane transporter activity
B565_RS07735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B565_RS07745	COG4160	amino acid transport
B565_RS07750	COG0564	pseudouridine synthase activity
B565_RS07765	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B565_RS07775	COG0625	glutathione transferase activity
B565_RS07785	COG2195	Cleaves the N-terminal amino acid of tripeptides
B565_RS07790	COG3069	C4-dicarboxylate transmembrane transporter activity
B565_RS07840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B565_RS07850	COG1091	dTDP-4-dehydrorhamnose reductase activity
B565_RS07875	COG0367	asparagine synthase
B565_RS07885	COG4651	solute:proton antiporter activity
B565_RS07885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B565_RS07890	COG0647	UMP catabolic process
B565_RS07895	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B565_RS07905	COG1902	pentaerythritol trinitrate reductase activity
B565_RS07910	COG1253	flavin adenine dinucleotide binding
B565_RS07920	COG0277	FAD linked oxidase domain protein
B565_RS07920	COG0247	lactate metabolic process
B565_RS07930	COG2050	protein possibly involved in aromatic compounds catabolism
B565_RS07940	COG2056	Na+-H+ antiporter family
B565_RS07945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B565_RS07950	COG0671	phosphoesterase, PA-phosphatase related
B565_RS07955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B565_RS07960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B565_RS07970	COG0101	tRNA pseudouridine synthase activity
B565_RS07975	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B565_RS07980	COG0285	dihydrofolate synthase activity
B565_RS07985	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
B565_RS07990	COG0393	Putative heavy-metal-binding
B565_RS08000	COG1648	precorrin-2 dehydrogenase activity
B565_RS08000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B565_RS08020	COG4667	esterase of the alpha-beta hydrolase superfamily
B565_RS08025	COG1619	proteins homologs of microcin C7 resistance protein MccF
B565_RS08030	COG1368	sulfuric ester hydrolase activity
B565_RS08040	COG0527	aspartate kinase activity
B565_RS08045	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B565_RS08045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B565_RS08050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B565_RS08070	COG0596	Alpha beta hydrolase
B565_RS08085	COG0577	efflux transmembrane transporter activity
B565_RS08090	COG1136	(ABC) transporter
B565_RS08105	COG2814	Major facilitator Superfamily
B565_RS08120	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
B565_RS08125	COG0672	)-iron permease
B565_RS08170	COG0659	secondary active sulfate transmembrane transporter activity
B565_RS08180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B565_RS08185	COG0326	Molecular chaperone. Has ATPase activity
B565_RS08190	COG4172	Belongs to the ABC transporter superfamily
B565_RS08195	COG4172	Belongs to the ABC transporter superfamily
B565_RS08205	COG4168	peptide transport system, permease
B565_RS08215	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B565_RS08220	COG1842	Phage shock protein A
B565_RS08235	COG3106	COG3106 Predicted ATPase
B565_RS08240	COG3768	UPF0283 membrane protein
B565_RS08245	COG0583	DNA-binding transcription factor activity
B565_RS08250	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B565_RS08255	COG3842	ATPase activity
B565_RS08260	COG1176	ABC-type spermidine putrescine transport system, permease component I
B565_RS08265	COG1177	transmembrane transport
B565_RS08270	COG1012	belongs to the aldehyde dehydrogenase family
B565_RS08280	COG2154	pterin-4-alpha-carbinolamine dehydratase
B565_RS08285	COG2154	pterin-4-alpha-carbinolamine dehydratase
B565_RS08300	COG2199	diguanylate cyclase activity
B565_RS08305	COG2885	chlorophyll binding
B565_RS08310	COG0861	Integral membrane protein TerC family
B565_RS08340	COG2910	NAD(P)H-binding
B565_RS08345	COG0583	DNA-binding transcription factor activity
B565_RS08350	COG0583	DNA-binding transcription factor activity
B565_RS08365	COG1335	isochorismatase
B565_RS08375	COG0583	DNA-binding transcription factor activity
B565_RS08380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B565_RS08390	COG0583	DNA-binding transcription factor activity
B565_RS08395	COG2723	6-phospho-beta-galactosidase activity
B565_RS08400	COG1944	ATP diphosphatase activity
B565_RS08405	COG2116	formate transmembrane transporter activity
B565_RS08410	COG1882	Formate acetyltransferase
B565_RS08415	COG2983	Belongs to the UPF0260 family
B565_RS08430	COG0058	SHG alpha-glucan phosphorylase activity
B565_RS08435	COG0471	metal ion transport
B565_RS08440	COG3118	belongs to the thioredoxin family
B565_RS08450	COG1132	(ABC) transporter
B565_RS08455	COG1132	(ABC) transporter
B565_RS08465	COG2501	S4 domain
B565_RS08480	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B565_RS08520	COG2009	succinate dehydrogenase
B565_RS08525	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B565_RS08530	COG1053	succinate dehydrogenase
B565_RS08540	COG0567	Dehydrogenase, E1 component
B565_RS08545	COG0508	dehydrogenase complex catalyzes the overall conversion of
B565_RS08550	COG0045	succinate-CoA ligase (ADP-forming) activity
B565_RS08560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B565_RS08570	COG3842	ATPase activity
B565_RS08575	COG1840	ABC-type Fe3 transport system, periplasmic component
B565_RS08585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B565_RS08595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B565_RS08610	COG4235	cytochrome complex assembly
B565_RS08610	COG3088	subunit of a heme lyase
B565_RS08620	COG1138	Cytochrome C-type biogenesis protein
B565_RS08625	COG3301	Polysulphide reductase, NrfD
B565_RS08630	COG0437	4 iron, 4 sulfur cluster binding
B565_RS08635	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
B565_RS08650	COG0247	lactate metabolic process
B565_RS08655	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
B565_RS08660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B565_RS08665	COG3012	SEC-C Motif Domain Protein
B565_RS08670	COG0840	transmembrane signaling receptor activity
B565_RS08675	COG1940	carbohydrate kinase activity
B565_RS08675	COG1846	Transcriptional regulator
B565_RS08680	COG3148	PFAM DTW domain containing protein
B565_RS08685	COG0730	response to heat
B565_RS08690	COG0583	DNA-binding transcription factor activity
B565_RS08705	COG3593	DNA synthesis involved in DNA repair
B565_RS08735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B565_RS08740	COG1011	Hydrolase
B565_RS08755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B565_RS08760	COG2832	Protein of unknown function (DUF454)
B565_RS08765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B565_RS08775	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B565_RS08785	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B565_RS08800	COG1560	Kdo2-lipid A biosynthetic process
B565_RS08805	COG1560	Kdo2-lipid A biosynthetic process
B565_RS08830	COG0417	DNA replication proofreading
B565_RS08845	COG1451	nucleotide metabolic process
B565_RS08860	COG3069	C4-dicarboxylate transmembrane transporter activity
B565_RS08875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B565_RS08875	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B565_RS08880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B565_RS08890	COG0569	domain protein
B565_RS08890	COG2985	domain, Protein
B565_RS08900	COG0556	nucleotide-excision repair
B565_RS08910	COG0586	Pfam SNARE associated Golgi protein
B565_RS08915	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B565_RS08920	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B565_RS08930	COG4681	YaeQ
B565_RS08940	COG2932	Transcriptional regulator
B565_RS09045	COG0640	Transcriptional regulator
B565_RS09055	COG4373	Mu-like prophage FluMu protein gp28
B565_RS09060	COG4383	Mu-like prophage protein gp29
B565_RS09080	COG4388	Caudovirus prohead serine protease
B565_RS09085	COG4397	Mu-like prophage major head subunit gpT
B565_RS09170	COG3829	transcription factor binding
B565_RS09215	COG0307	riboflavin synthase, alpha
B565_RS09225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B565_RS09230	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B565_RS09235	COG0697	spore germination
B565_RS09240	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B565_RS09280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B565_RS09285	COG3099	Belongs to the UPF0263 family
B565_RS09290	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B565_RS09295	COG2894	cell division
B565_RS09300	COG0850	regulation of cytokinetic process
B565_RS09305	COG3100	YcgL domain-containing protein
B565_RS09320	COG1760	l-serine dehydratase
B565_RS09325	COG1760	l-serine dehydratase
B565_RS09330	COG3123	guanosine phosphorylase activity
B565_RS09335	COG1301	dicarboxylic acid transport
B565_RS09340	COG0205	6-phosphofructokinase activity
B565_RS09350	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B565_RS09355	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B565_RS09365	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
B565_RS09370	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
B565_RS09375	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B565_RS09410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B565_RS09415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B565_RS09420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B565_RS09430	COG0549	Belongs to the carbamate kinase family
B565_RS09435	COG0697	spore germination
B565_RS09440	COG3608	succinylglutamate desuccinylase aspartoacylase
B565_RS09440	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B565_RS09445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B565_RS09450	COG2068	MobA-Related Protein
B565_RS09455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B565_RS09455	COG0493	'glutamate synthase
B565_RS09460	COG0402	S-adenosylhomocysteine deaminase activity
B565_RS09465	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B565_RS09470	COG2080	2 iron, 2 sulfur cluster binding
B565_RS09470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B565_RS09475	COG2233	PERMEase
B565_RS09480	COG0402	S-adenosylhomocysteine deaminase activity
B565_RS09485	COG2252	PERMEase
B565_RS09490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B565_RS09495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B565_RS09500	COG2080	2 iron, 2 sulfur cluster binding
B565_RS09515	COG3134	Outer membrane lipoprotein
B565_RS09525	COG0318	PFAM AMP-dependent synthetase and ligase
B565_RS09530	COG2199	diguanylate cyclase activity
B565_RS09545	COG0107	imidazoleglycerol-phosphate synthase activity
B565_RS09550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B565_RS09555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B565_RS09560	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B565_RS09560	COG0131	Imidazoleglycerol-phosphate dehydratase
B565_RS09565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B565_RS09570	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B565_RS09575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B565_RS09585	COG1199	ATP-dependent helicase activity
B565_RS09590	COG1214	PFAM Peptidase M22, glycoprotease
B565_RS09600	COG2267	carboxylic ester hydrolase activity
B565_RS09605	COG0318	PFAM AMP-dependent synthetase and ligase
B565_RS09615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B565_RS09620	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
B565_RS09625	COG0709	Synthesizes selenophosphate from selenide and ATP
B565_RS09640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B565_RS09645	COG0840	transmembrane signaling receptor activity
B565_RS09650	COG1254	Belongs to the acylphosphatase family
B565_RS09660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B565_RS09660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B565_RS09665	COG0489	protein tyrosine kinase activity
B565_RS09670	COG0572	uridine kinase
B565_RS09675	COG0717	Belongs to the dCTP deaminase family
B565_RS09680	COG0306	phosphate transporter
B565_RS09685	COG3313	Fe-S protein
B565_RS09690	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B565_RS09695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B565_RS09700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B565_RS09705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B565_RS09715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B565_RS09725	COG0366	Alpha amylase catalytic
B565_RS09740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B565_RS09745	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B565_RS09750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B565_RS09755	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B565_RS09760	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B565_RS09765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B565_RS09765	COG0072	phenylalanine-tRNA ligase activity
B565_RS09770	COG0776	regulation of translation
B565_RS09775	COG2205	protein histidine kinase activity
B565_RS09775	COG0784	Response regulator, receiver
B565_RS09800	COG5001	Diguanylate cyclase
B565_RS09800	COG3300	MHYT domain
B565_RS09805	COG1609	Transcriptional regulator
B565_RS09810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B565_RS09815	COG1879	ABC-type sugar transport system periplasmic component
B565_RS09820	COG1172	Belongs to the binding-protein-dependent transport system permease family
B565_RS09825	COG1129	ABC transporter
B565_RS09830	COG1869	D-ribose catabolic process
B565_RS09835	COG0625	glutathione transferase activity
B565_RS09845	COG1177	transmembrane transport
B565_RS09870	COG0037	tRNA processing
B565_RS09875	COG0589	response to stress
B565_RS09880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B565_RS09895	COG2217	Heavy metal translocating P-type atpase
B565_RS09905	COG2010	Cytochrome c
B565_RS09920	COG3278	Belongs to the heme-copper respiratory oxidase family
B565_RS09930	COG1956	GAF domain-containing protein
B565_RS09935	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
B565_RS09945	COG0308	aminopeptidase N
B565_RS09955	COG2902	Dehydrogenase
B565_RS09960	COG0167	dihydroorotate dehydrogenase activity
B565_RS09975	COG0254	rRNA binding
B565_RS09980	COG0116	Belongs to the methyltransferase superfamily
B565_RS09980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B565_RS09990	COG0488	(ABC) transporter
B565_RS09995	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B565_RS10000	COG1067	ATP-dependent peptidase activity
B565_RS10025	COG3141	response to X-ray
B565_RS10030	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B565_RS10035	COG4221	oxidoreductase activity
B565_RS10080	COG0372	Belongs to the citrate synthase family
B565_RS10085	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B565_RS10095	COG2995	paraquat-inducible protein a
B565_RS10100	COG3008	intermembrane lipid transfer
B565_RS10105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B565_RS10105	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
B565_RS10120	COG0084	hydrolase, TatD family'
B565_RS10125	COG0470	DNA polymerase III
B565_RS10130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B565_RS10135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B565_RS10140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B565_RS10145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B565_RS10150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B565_RS10155	COG1028	Short-chain dehydrogenase reductase Sdr
B565_RS10165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B565_RS10170	COG0416	fatty acid biosynthetic process
B565_RS10175	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B565_RS10180	COG1399	metal-binding, possibly nucleic acid-binding protein
B565_RS10185	COG0424	maF-like protein
B565_RS10200	COG1530	ribonuclease E activity
B565_RS10205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B565_RS10205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B565_RS10205	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B565_RS10210	COG1105	Belongs to the carbohydrate kinase PfkB family
B565_RS10215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS10215	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS10220	COG1609	Transcriptional regulator
B565_RS10225	COG0814	amino acid
B565_RS10235	COG3788	relative of glutathione S-transferase, MAPEG superfamily
B565_RS10245	COG0513	Belongs to the DEAD box helicase family
B565_RS10255	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B565_RS10260	COG2890	protein-(glutamine-N5) methyltransferase activity
B565_RS10265	COG2840	Smr protein MutS2
B565_RS10270	COG3706	GGDEF domain
B565_RS10290	COG2824	Alkylphosphonate utilization operon protein PhnA
B565_RS10305	COG0494	nUDIX hydrolase
B565_RS10310	COG0814	amino acid
B565_RS10320	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
B565_RS10325	COG0514	ATP-dependent DNA helicase (RecQ)
B565_RS10330	COG2766	serine protein kinase
B565_RS10335	COG2718	Belongs to the UPF0229 family
B565_RS10340	COG2719	SpoVR family
B565_RS10345	COG1024	Enoyl-CoA hydratase
B565_RS10345	COG1250	3-hydroxyacyl-CoA dehydrogenase
B565_RS10350	COG0183	Belongs to the thiolase family
B565_RS10355	COG0714	Associated with various cellular activities
B565_RS10375	COG2304	oxidoreductase activity
B565_RS10385	COG1595	DNA-templated transcription, initiation
B565_RS10400	COG2067	long-chain fatty acid transport protein
B565_RS10405	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
B565_RS10410	COG0183	Belongs to the thiolase family
B565_RS10420	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B565_RS10430	COG1643	Atp-dependent helicase
B565_RS10435	COG0617	tRNA 3'-terminal CCA addition
B565_RS10435	COG0517	IMP dehydrogenase activity
B565_RS10435	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B565_RS10440	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B565_RS10445	COG3119	arylsulfatase activity
B565_RS10450	COG0714	Associated with various cellular activities
B565_RS10465	COG2304	oxidoreductase activity
B565_RS10470	COG2304	oxidoreductase activity
B565_RS10495	COG0641	radical SAM
B565_RS10505	COG5001	Diguanylate cyclase
B565_RS10535	COG0840	transmembrane signaling receptor activity
B565_RS10605	COG2925	Exonuclease
B565_RS10615	COG3345	alpha-galactosidase
B565_RS10620	COG1380	Effector of murein hydrolase LrgA
B565_RS10625	COG1346	cytolysis
B565_RS10630	COG0295	cytidine deaminase activity
B565_RS10635	COG3033	Beta-eliminating lyase
B565_RS10640	COG3046	protein related to deoxyribodipyrimidine photolyase
B565_RS10645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B565_RS10650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B565_RS10670	COG3383	formate dehydrogenase (NAD+) activity
B565_RS10675	COG3383	formate dehydrogenase (NAD+) activity
B565_RS10680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B565_RS10685	COG0454	-acetyltransferase
B565_RS10690	COG3158	transport of potassium into the cell
B565_RS10695	COG0800	Aldolase
B565_RS10700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B565_RS10710	COG1028	Short-chain dehydrogenase reductase Sdr
B565_RS10725	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B565_RS10730	COG4821	SIS domain
B565_RS10735	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B565_RS10735	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS10740	COG3716	PTS system mannose fructose sorbose family IID component
B565_RS10745	COG3715	PTS system
B565_RS10750	COG2188	Transcriptional regulator
B565_RS10755	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B565_RS10760	COG0651	ATP synthesis coupled electron transport
B565_RS10765	COG0650	Formate hydrogenlyase subunit 4
B565_RS10770	COG3261	NADH dehydrogenase
B565_RS10770	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
B565_RS10775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B565_RS10780	COG3260	NADH ubiquinone oxidoreductase 20
B565_RS10790	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B565_RS10795	COG1921	L-seryl-tRNASec selenium transferase activity
B565_RS10805	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B565_RS10810	COG0298	carbon dioxide binding
B565_RS10820	COG0309	Hydrogenase expression formation protein (HypE)
B565_RS10825	COG0375	protein maturation
B565_RS10830	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B565_RS10835	COG3842	ATPase activity
B565_RS10840	COG0444	Belongs to the ABC transporter superfamily
B565_RS10845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B565_RS10860	COG1773	rubredoxin
B565_RS10865	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B565_RS10870	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
B565_RS10875	COG5557	Pfam Polysulphide reductase, NrfD
B565_RS10880	COG0437	4 iron, 4 sulfur cluster binding
B565_RS10885	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
B565_RS10890	COG5001	Diguanylate cyclase
B565_RS10890	COG3706	GGDEF domain
B565_RS10890	COG2203	Gaf domain
B565_RS10890	COG4251	negative regulation of phosphorylation
B565_RS10895	COG0438	transferase activity, transferring glycosyl groups
B565_RS10900	COG0438	transferase activity, transferring glycosyl groups
B565_RS10920	COG0438	transferase activity, transferring glycosyl groups
B565_RS10955	COG0438	transferase activity, transferring glycosyl groups
B565_RS10960	COG1215	transferase activity, transferring glycosyl groups
B565_RS10965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B565_RS11010	COG3437	response regulator, receiver
B565_RS11010	COG2205	protein histidine kinase activity
B565_RS11010	COG3850	Histidine kinase
B565_RS11010	COG4999	Histidine kinase
B565_RS11035	COG0730	response to heat
B565_RS11045	COG1028	Short-chain dehydrogenase reductase Sdr
B565_RS11055	COG1024	Enoyl-CoA hydratase
B565_RS11060	COG1024	Enoyl-CoA hydratase
B565_RS11065	COG1960	acyl-CoA dehydrogenase activity
B565_RS11070	COG1960	acyl-CoA dehydrogenase activity
B565_RS11075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B565_RS11080	COG1024	Enoyl-CoA hydratase
B565_RS11110	COG1584	GPR1 FUN34 yaaH family protein
B565_RS11125	COG1115	amino acid carrier protein
B565_RS11130	COG3385	transposase activity
B565_RS11180	COG4695	Portal protein
B565_RS11185	COG1024	Enoyl-CoA hydratase
B565_RS11200	COG3162	membrane
B565_RS11205	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B565_RS11210	COG0488	(ABC) transporter
B565_RS11215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B565_RS11220	COG0776	regulation of translation
B565_RS11225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B565_RS11230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B565_RS11235	COG0740	serine-type endopeptidase activity
B565_RS11240	COG0544	peptidyl-prolyl cis-trans isomerase activity
B565_RS11250	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
B565_RS11255	COG4591	ABC-type transport system involved in lipoprotein release permease component
B565_RS11260	COG1136	(ABC) transporter
B565_RS11265	COG4591	ABC-type transport system involved in lipoprotein release permease component
B565_RS11275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B565_RS11280	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B565_RS11285	COG4166	transmembrane transport
B565_RS11290	COG0697	spore germination
B565_RS11300	COG2062	phosphohistidine phosphatase, SixA
B565_RS11305	COG1025	Belongs to the peptidase M16 family
B565_RS11350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B565_RS11350	COG0519	Catalyzes the synthesis of GMP from XMP
B565_RS11355	COG0516	GMP reductase activity
B565_RS11355	COG0517	IMP dehydrogenase activity
B565_RS11360	COG3038	cytochrome b561
B565_RS11365	COG1570	exodeoxyribonuclease VII activity
B565_RS11370	COG2188	Transcriptional regulator
B565_RS11375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B565_RS11375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B565_RS11375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS11380	COG0383	alpha-mannosidase activity
B565_RS11385	COG1181	Belongs to the D-alanine--D-alanine ligase family
B565_RS11395	COG0386	Belongs to the glutathione peroxidase family
B565_RS11400	COG0513	Belongs to the DEAD box helicase family
B565_RS11415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B565_RS11420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B565_RS11425	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B565_RS11475	COG5001	Diguanylate cyclase
B565_RS11475	COG3300	MHYT domain
B565_RS11490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B565_RS11500	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B565_RS11505	COG0563	adenylate kinase activity
B565_RS11515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B565_RS11520	COG1286	toxin biosynthetic process
B565_RS11525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B565_RS11530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B565_RS11535	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B565_RS11540	COG0531	amino acid
B565_RS11540	COG1674	ftsk spoiiie
B565_RS11550	COG0686	Belongs to the AlaDH PNT family
B565_RS11555	COG0492	ferredoxin-NADP+ reductase activity
B565_RS11560	COG3706	GGDEF domain
B565_RS11565	COG3134	Outer membrane lipoprotein
B565_RS11570	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B565_RS11575	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B565_RS11580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B565_RS11585	COG0542	response to heat
B565_RS11590	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B565_RS11595	COG1278	Cold shock
B565_RS11600	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B565_RS11620	COG0745	RESPONSE REGULATOR receiver
B565_RS11625	COG2205	protein histidine kinase activity
B565_RS11635	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B565_RS11635	COG0392	lysyltransferase activity
B565_RS11660	COG1435	thymidine kinase activity
B565_RS11665	COG1757	Na H antiporter
B565_RS11670	COG2916	Histone family protein nucleoid-structuring protein H-NS
B565_RS11675	COG2096	Adenosyltransferase
B565_RS11680	COG3530	Putative quorum-sensing-regulated virulence factor
B565_RS11685	COG0602	queuosine metabolic process
B565_RS11690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B565_RS11710	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B565_RS11720	COG0776	regulation of translation
B565_RS11725	COG0539	negative regulation of cytoplasmic translation
B565_RS11730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B565_RS11735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B565_RS11750	COG2814	Major facilitator Superfamily
B565_RS11770	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B565_RS11775	COG5001	Diguanylate cyclase
B565_RS11775	COG3300	MHYT domain
B565_RS11780	COG0583	DNA-binding transcription factor activity
B565_RS11785	COG3437	response regulator, receiver
B565_RS11810	COG4989	oxidoreductase activity
B565_RS11815	COG0724	RNA recognition motif
B565_RS11825	COG1126	abc transporter atp-binding protein
B565_RS11830	COG0765	amino acid transport
B565_RS11835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B565_RS11840	COG4597	amino acid ABC transporter
B565_RS11845	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
B565_RS11855	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B565_RS11870	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B565_RS11875	COG1360	Flagellar Motor Protein
B565_RS11880	COG4771	TonB-dependent receptor
B565_RS11885	COG1770	oligopeptidase
B565_RS11905	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B565_RS11910	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B565_RS11915	COG0649	NAD binding
B565_RS11915	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B565_RS11930	COG1034	ATP synthesis coupled electron transport
B565_RS11935	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B565_RS11940	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B565_RS11945	COG0839	Belongs to the complex I subunit 6 family
B565_RS11950	COG0713	ATP synthesis coupled electron transport
B565_RS11960	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B565_RS11965	COG1007	ATP synthesis coupled electron transport
B565_RS11980	COG2199	diguanylate cyclase activity
B565_RS11980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B565_RS11985	COG0047	phosphoribosylformylglycinamidine synthase activity
B565_RS11985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B565_RS11990	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
B565_RS11995	COG1645	bacterial-type flagellum-dependent swarming motility
B565_RS12000	COG1160	GTP binding
B565_RS12005	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B565_RS12010	COG2976	Protein conserved in bacteria
B565_RS12015	COG0124	histidyl-tRNA synthetase
B565_RS12020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B565_RS12035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B565_RS12040	COG0105	UTP biosynthetic process
B565_RS12055	COG0633	Ferredoxin
B565_RS12060	COG0443	Heat shock 70 kDa protein
B565_RS12065	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B565_RS12075	COG0822	iron-sulfur transferase activity
B565_RS12080	COG1104	cysteine desulfurase activity
B565_RS12100	COG3154	lipid carrier protein
B565_RS12105	COG0826	peptidase U32
B565_RS12110	COG0826	peptidase U32
B565_RS12125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B565_RS12130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B565_RS12135	COG1862	Preprotein translocase
B565_RS12140	COG0343	queuine tRNA-ribosyltransferase activity
B565_RS12145	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B565_RS12150	COG0517	IMP dehydrogenase activity
B565_RS12160	COG3634	alkyl hydroperoxide reductase activity
B565_RS12205	COG1242	4 iron, 4 sulfur cluster binding
B565_RS12215	COG0067	glutamate synthase
B565_RS12215	COG0069	glutamate synthase activity
B565_RS12215	COG0070	glutamate synthase
B565_RS12220	COG0493	'glutamate synthase
B565_RS12230	COG0513	Belongs to the DEAD box helicase family
B565_RS12255	COG0023	Translation Initiation Factor
B565_RS12260	COG2119	membrane
B565_RS12305	COG0215	cysteine-tRNA ligase activity
B565_RS12310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B565_RS12320	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B565_RS12330	COG2261	transglycosylase associated protein
B565_RS12335	COG0642	Histidine kinase
B565_RS12365	COG4974	Belongs to the 'phage' integrase family
B565_RS12450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B565_RS12465	COG4695	Portal protein
B565_RS12635	COG0322	excinuclease ABC activity
B565_RS12640	COG2197	response regulator
B565_RS12645	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B565_RS12650	COG2835	tetraacyldisaccharide 4'-kinase activity
B565_RS12655	COG1663	tetraacyldisaccharide 4'-kinase activity
B565_RS12665	COG2333	competence protein COMEC
B565_RS12665	COG0658	competence protein
B565_RS12680	COG1448	Aminotransferase
B565_RS12690	COG0583	DNA-binding transcription factor activity
B565_RS12695	COG3085	chromosome segregation
B565_RS12700	COG4574	serine-type endopeptidase inhibitor activity
B565_RS12705	COG0584	glycerophosphoryl diester phosphodiesterase
B565_RS12715	COG1349	DNA-binding transcription factor activity
B565_RS12720	COG2271	Major facilitator Superfamily
B565_RS12725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B565_RS12730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B565_RS12735	COG0840	transmembrane signaling receptor activity
B565_RS12745	COG0583	DNA-binding transcription factor activity
B565_RS12765	COG0656	L-ascorbic acid biosynthetic process
B565_RS12775	COG2814	Major facilitator Superfamily
B565_RS12780	COG2249	NAD(P)H dehydrogenase (quinone) activity
B565_RS12795	COG3220	belongs to the UPF0276 family
B565_RS12815	COG1294	oxidase, subunit
B565_RS12825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B565_RS12835	COG2979	Protein of unknown function (DUF533)
B565_RS12845	COG0583	DNA-binding transcription factor activity
B565_RS12850	COG2807	transmembrane transport
B565_RS12855	COG1187	pseudouridine synthase activity
B565_RS12865	COG0346	lactoylglutathione lyase activity
B565_RS12895	COG4657	Part of a membrane complex involved in electron transport
B565_RS12900	COG2878	Part of a membrane complex involved in electron transport
B565_RS12910	COG4658	electron transport chain
B565_RS12915	COG4659	FMN binding
B565_RS12920	COG4660	Part of a membrane complex involved in electron transport
B565_RS12925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B565_RS12930	COG0346	lactoylglutathione lyase activity
B565_RS12955	COG2801	Transposase and inactivated derivatives
B565_RS12965	COG1199	ATP-dependent helicase activity
B565_RS12975	COG0123	including yeast histone deacetylase and acetoin utilization protein
B565_RS12980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B565_RS12985	COG1785	Belongs to the alkaline phosphatase family
B565_RS13005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B565_RS13010	COG2197	response regulator
B565_RS13020	COG2271	Major facilitator Superfamily
B565_RS13025	COG3706	GGDEF domain
B565_RS13030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B565_RS13035	COG0765	amino acid transport
B565_RS13040	COG1126	abc transporter atp-binding protein
B565_RS13055	COG0531	amino acid
B565_RS13070	COG1253	flavin adenine dinucleotide binding
B565_RS13075	COG0704	Plays a role in the regulation of phosphate uptake
B565_RS13080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B565_RS13085	COG0581	inorganic phosphate transmembrane transporter activity
B565_RS13090	COG0573	inorganic phosphate transmembrane transporter activity
B565_RS13095	COG0590	tRNA wobble adenosine to inosine editing
B565_RS13105	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B565_RS13125	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B565_RS13130	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B565_RS13135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B565_RS13140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B565_RS13165	COG2716	regulation of RNA biosynthetic process
B565_RS13170	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B565_RS13180	COG2239	Acts as a magnesium transporter
B565_RS13185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B565_RS13200	COG1706	bacterial-type flagellum-dependent cell motility
B565_RS13205	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
B565_RS13215	COG4787	bacterial-type flagellum-dependent cell motility
B565_RS13235	COG1815	bacterial-type flagellum-dependent cell motility
B565_RS13240	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B565_RS13245	COG0784	Response regulator, receiver
B565_RS13245	COG0835	chemotaxis
B565_RS13250	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
B565_RS13265	COG0622	Phosphoesterase
B565_RS13270	COG4166	transmembrane transport
B565_RS13285	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B565_RS13295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B565_RS13300	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B565_RS13305	COG1882	Formate acetyltransferase
B565_RS13310	COG1349	DNA-binding transcription factor activity
B565_RS13315	COG0697	spore germination
B565_RS13320	COG4166	transmembrane transport
B565_RS13345	COG1278	Cold shock
B565_RS13370	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B565_RS13370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B565_RS13375	COG1028	Short-chain dehydrogenase reductase Sdr
B565_RS13380	COG1535	isochorismatase
B565_RS13380	COG3433	isochorismatase activity
B565_RS13385	COG1021	2,3-dihydroxybenzoate-AMP ligase
B565_RS13390	COG1169	isochorismate synthase
B565_RS13395	COG4771	TonB-dependent receptor
B565_RS13400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B565_RS13410	COG0741	lytic transglycosylase activity
B565_RS13420	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B565_RS13440	COG2911	Protein conserved in bacteria
B565_RS13445	COG0729	surface antigen
B565_RS13455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B565_RS13465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B565_RS13475	COG4134	Bacterial extracellular solute-binding protein
B565_RS13485	COG4136	ATPase activity
B565_RS13490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B565_RS13495	COG2951	lytic endotransglycosylase activity
B565_RS13500	COG1846	Transcriptional regulator
B565_RS13510	COG0033	Phosphoglucomutase
B565_RS13515	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
B565_RS13520	COG0596	Alpha beta hydrolase
B565_RS13535	COG0716	FMN binding
B565_RS13545	COG0735	belongs to the Fur family
B565_RS13550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B565_RS13560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B565_RS13560	COG2190	(PTS) system
B565_RS13560	COG1263	PTS System
B565_RS13565	COG0363	glucosamine-6-phosphate deaminase activity
B565_RS13570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B565_RS13575	COG1940	carbohydrate kinase activity
B565_RS13575	COG1846	Transcriptional regulator
B565_RS13580	COG2194	sulfuric ester hydrolase activity
B565_RS13585	COG2199	diguanylate cyclase activity
B565_RS13585	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B565_RS13590	COG3275	phosphorelay sensor kinase activity
B565_RS13595	COG3279	Response regulator of the LytR AlgR family
B565_RS13600	COG1966	Carbon starvation protein
B565_RS13610	COG1566	PFAM secretion protein HlyD family protein
B565_RS13615	COG1061	Type III restriction enzyme res subunit
B565_RS13620	COG2027	D-alanyl-D-alanine carboxypeptidase
B565_RS13625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B565_RS13630	COG3021	interspecies interaction between organisms
B565_RS13640	COG1607	acyl-coa hydrolase
B565_RS13645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B565_RS13655	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B565_RS13655	COG1013	pyruvate-flavodoxin oxidoreductase activity
B565_RS13655	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B565_RS13655	COG0674	pyruvate-flavodoxin oxidoreductase activity
B565_RS13670	COG0633	Ferredoxin
B565_RS13670	COG3217	Mosc domain protein beta barrel domain protein
B565_RS13670	COG3217	Mosc domain protein beta barrel domain protein
B565_RS13670	COG0633	Ferredoxin
B565_RS13680	COG0501	Belongs to the peptidase M48B family
B565_RS13685	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B565_RS13690	COG1073	alpha beta
B565_RS13690	COG2226	methyltransferase
B565_RS13695	COG0156	8-amino-7-oxononanoate synthase activity
B565_RS13700	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B565_RS13705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B565_RS13720	COG0017	Asparaginyl-tRNA synthetase
B565_RS13730	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B565_RS13740	COG1473	amidohydrolase
B565_RS13745	COG3069	C4-dicarboxylate transmembrane transporter activity
B565_RS13755	COG1393	Belongs to the ArsC family
B565_RS13760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B565_RS13765	COG1876	peptidase activity
B565_RS13770	COG3263	regulation of cellular component size
B565_RS13785	COG1280	lysine exporter protein (LysE YggA)
B565_RS13815	COG0564	pseudouridine synthase activity
B565_RS13825	COG1454	alcohol dehydrogenase
B565_RS13865	COG2894	cell division
B565_RS13875	COG4964	Belongs to the GSP D family
B565_RS13905	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B565_RS13910	COG0702	epimerase
B565_RS13920	COG0095	Lipoate-protein ligase
B565_RS13930	COG1136	(ABC) transporter
B565_RS13930	COG0577	efflux transmembrane transporter activity
B565_RS13935	COG1136	(ABC) transporter
B565_RS13935	COG0577	efflux transmembrane transporter activity
B565_RS13940	COG0577	efflux transmembrane transporter activity
B565_RS13940	COG1136	(ABC) transporter
B565_RS13945	COG1566	PFAM secretion protein HlyD family protein
B565_RS13980	COG0446	pyridine nucleotide-disulphide oxidoreductase
B565_RS13990	COG1285	pathogenesis
B565_RS14020	COG0484	heat shock protein binding
B565_RS14025	COG0443	Heat shock 70 kDa protein
B565_RS14030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B565_RS14035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B565_RS14040	COG0497	DNA recombination
B565_RS14045	COG1227	inorganic diphosphatase activity
B565_RS14050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B565_RS14055	COG0577	efflux transmembrane transporter activity
B565_RS14055	COG1136	(ABC) transporter
B565_RS14085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B565_RS14105	COG1086	Polysaccharide biosynthesis protein
B565_RS14120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B565_RS14120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B565_RS14125	COG1028	Short-chain dehydrogenase reductase Sdr
B565_RS14130	COG1083	cytidylyl-transferase
B565_RS14135	COG0673	inositol 2-dehydrogenase activity
B565_RS14140	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B565_RS14150	COG2089	acid synthase
B565_RS14155	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B565_RS14160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B565_RS14175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B565_RS14180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B565_RS14185	COG1309	transcriptional regulator
B565_RS14200	COG1342	Belongs to the UPF0251 family
B565_RS14220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B565_RS14235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B565_RS14240	COG0083	homoserine kinase activity
B565_RS14250	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
B565_RS14255	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
B565_RS14260	COG1946	Acyl-CoA thioesterase
B565_RS14270	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B565_RS14280	COG0009	L-threonylcarbamoyladenylate synthase
B565_RS14290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B565_RS14295	COG0512	Glutamine amidotransferase of anthranilate synthase
B565_RS14295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B565_RS14300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B565_RS14305	COG0135	phosphoribosylanthranilate isomerase activity
B565_RS14305	COG0134	indole-3-glycerol-phosphate synthase activity
B565_RS14310	COG0133	tryptophan synthase activity
B565_RS14315	COG0159	tryptophan synthase activity
B565_RS14325	COG1988	membrane-bound metal-dependent
B565_RS14340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B565_RS14350	COG0798	PFAM Bile acid sodium symporter
B565_RS14380	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B565_RS14390	COG0745	RESPONSE REGULATOR receiver
B565_RS14405	COG4988	ABC transporter
B565_RS14410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B565_RS14430	COG1720	tRNA m6t6A37 methyltransferase activity
B565_RS14435	COG3038	cytochrome b561
B565_RS14475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B565_RS14480	COG1396	sequence-specific DNA binding
B565_RS14480	COG1917	Cupin 2, conserved barrel domain protein
B565_RS14485	COG1012	belongs to the aldehyde dehydrogenase family
B565_RS14495	COG0531	amino acid
B565_RS14505	COG0531	amino acid
B565_RS14510	COG1283	sodium-dependent phosphate transmembrane transporter activity
B565_RS14515	COG0545	Peptidyl-prolyl cis-trans isomerase
B565_RS14520	COG0405	Gamma-glutamyltransferase
B565_RS14525	COG2974	May be involved in recombination
B565_RS14535	COG0420	3'-5' exonuclease activity
B565_RS14540	COG0419	ATPase involved in DNA repair
B565_RS14545	COG3384	dioxygenase
B565_RS14555	COG0469	pyruvate kinase activity
B565_RS14560	COG3264	Mechanosensitive ion channel
B565_RS14560	COG1196	nuclear chromosome segregation
B565_RS14580	COG3590	peptidase
B565_RS14590	COG2190	(PTS) system
B565_RS14600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS14605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B565_RS14610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B565_RS14625	COG3437	response regulator, receiver
B565_RS14625	COG2770	Histidine kinase
B565_RS14630	COG3409	Peptidoglycan-binding domain 1 protein
B565_RS14630	COG3267	Type II secretory pathway component ExeA
B565_RS14650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B565_RS14655	COG1459	type II secretion system
B565_RS14660	COG2165	general secretion pathway protein
B565_RS14670	COG2165	general secretion pathway protein
B565_RS14675	COG4795	General secretion pathway protein
B565_RS14680	COG3156	type II secretion system protein K
B565_RS14690	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
B565_RS14700	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B565_RS14705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B565_RS14710	COG2723	6-phospho-beta-galactosidase activity
B565_RS14715	COG1447	Phosphotransferase system cellobiose-specific component IIA
B565_RS14720	COG1917	Cupin 2, conserved barrel domain protein
B565_RS14720	COG2169	Transcriptional regulator
B565_RS14725	COG1486	melibiose metabolic process
B565_RS14740	COG0670	Belongs to the BI1 family
B565_RS14745	COG1289	transmembrane transporter activity
B565_RS14750	COG2920	part of a sulfur-relay system
B565_RS14755	COG0673	inositol 2-dehydrogenase activity
B565_RS14760	COG0583	DNA-binding transcription factor activity
B565_RS14800	COG1032	radical SAM domain protein
B565_RS14810	COG1566	PFAM secretion protein HlyD family protein
B565_RS14815	COG3706	GGDEF domain
B565_RS14820	COG1752	Esterase of the alpha-beta hydrolase superfamily
B565_RS14825	COG0531	amino acid
B565_RS14855	COG0281	malic enzyme
B565_RS14865	COG0534	Mate efflux family protein
B565_RS14880	COG2233	PERMEase
B565_RS14885	COG0095	Lipoate-protein ligase
B565_RS14895	COG1115	amino acid carrier protein
B565_RS14900	COG0019	diaminopimelate decarboxylase activity
B565_RS14910	COG0678	peroxiredoxin activity
B565_RS14935	COG0545	Peptidyl-prolyl cis-trans isomerase
B565_RS14940	COG3142	Participates in the control of copper homeostasis
B565_RS14965	COG5002	protein histidine kinase activity
B565_RS14970	COG0745	RESPONSE REGULATOR receiver
B565_RS14975	COG0346	lactoylglutathione lyase activity
B565_RS14980	COG3284	Transcriptional regulator
B565_RS14995	COG0697	spore germination
B565_RS15005	COG3290	protein histidine kinase activity
B565_RS15010	COG0281	malic enzyme
B565_RS15025	COG1846	Transcriptional regulator
B565_RS15030	COG1566	PFAM secretion protein HlyD family protein
B565_RS15060	COG0602	queuosine metabolic process
B565_RS15065	COG1328	CTP reductase activity
B565_RS15075	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B565_RS15080	COG3115	cell septum assembly
B565_RS15085	COG1196	nuclear chromosome segregation
B565_RS15095	COG2860	membrane
B565_RS15105	COG3108	Peptidase M15
B565_RS15110	COG2989	Protein conserved in bacteria
B565_RS15125	COG0463	Glycosyl transferase, family 2
B565_RS15140	COG0366	Alpha amylase catalytic
B565_RS15175	COG2199	diguanylate cyclase activity
B565_RS15175	COG2203	Gaf domain
B565_RS15185	COG3590	peptidase
B565_RS15195	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B565_RS15200	COG1982	Orn Lys Arg decarboxylase major
B565_RS15205	COG0531	amino acid
B565_RS15210	COG3710	Transcriptional regulator
B565_RS15215	COG0531	amino acid
B565_RS15235	COG0814	amino acid
B565_RS15265	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B565_RS15270	COG0739	heme binding
B565_RS15275	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B565_RS15285	COG0251	oxidation-reduction process
B565_RS15290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B565_RS15300	COG3091	SprT-like family
B565_RS15310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B565_RS15315	COG0189	ligase activity
B565_RS15320	COG1678	Uncharacterized ACR, COG1678
B565_RS15325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B565_RS15330	COG3104	oligopeptide transport
B565_RS15345	COG0714	Associated with various cellular activities
B565_RS15360	COG1115	amino acid carrier protein
B565_RS15365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B565_RS15375	COG0825	malonyl-CoA metabolic process
B565_RS15385	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B565_RS15390	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B565_RS15395	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B565_RS15400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B565_RS15405	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B565_RS15420	COG0750	zinc metalloprotease
B565_RS15425	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B565_RS15430	COG0575	Belongs to the CDS family
B565_RS15435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B565_RS15440	COG0233	cytoplasmic translational termination
B565_RS15445	COG0528	UMP kinase activity
B565_RS15450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B565_RS15455	COG0052	Belongs to the universal ribosomal protein uS2 family
B565_RS15460	COG0024	Methionine aminopeptidase
B565_RS15470	COG2171	N-acyltransferase activity
B565_RS15480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B565_RS15480	COG1263	PTS System
B565_RS15490	COG4580	involved in the transport of maltose and maltodextrins
B565_RS15500	COG0564	pseudouridine synthase activity
B565_RS15505	COG3098	single-species biofilm formation
B565_RS15530	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
B565_RS15540	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B565_RS15540	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B565_RS15555	COG1611	Belongs to the LOG family
B565_RS15560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B565_RS15565	COG0473	3-isopropylmalate dehydrogenase activity
B565_RS15575	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
B565_RS15580	COG2363	Small membrane protein
B565_RS15590	COG0583	DNA-binding transcription factor activity
B565_RS15595	COG0840	transmembrane signaling receptor activity
B565_RS15600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B565_RS15615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B565_RS15620	COG1666	GTP binding
B565_RS15630	COG2211	Major facilitator Superfamily
B565_RS15635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B565_RS15645	COG2813	Specifically methylates the guanine in position
B565_RS15650	COG0271	Belongs to the BolA IbaG family
B565_RS15655	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B565_RS15660	COG1805	sodium ion transport
B565_RS15665	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B565_RS15670	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B565_RS15675	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B565_RS15680	COG2871	sodium ion transport
B565_RS15685	COG1477	protein flavinylation
B565_RS15715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B565_RS15730	COG0300	oxidoreductase activity
B565_RS15740	COG0415	Belongs to the DNA photolyase family
B565_RS15745	COG0789	Transcriptional regulator
B565_RS15750	COG3272	Protein of unknown function (DUF1722)
B565_RS15780	COG1605	Chorismate mutase
B565_RS15780	COG0077	Prephenate dehydratase
B565_RS15810	COG5377	YqaJ viral recombinase family
B565_RS15865	COG0602	queuosine metabolic process
B565_RS15870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B565_RS15890	COG0514	ATP-dependent DNA helicase (RecQ)
B565_RS15910	COG0514	ATP-dependent DNA helicase (RecQ)
B565_RS15915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B565_RS15925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B565_RS15960	COG0840	transmembrane signaling receptor activity
B565_RS15970	COG0300	oxidoreductase activity
B565_RS15995	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B565_RS16035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B565_RS16040	COG0826	peptidase U32
B565_RS16045	COG1280	lysine exporter protein (LysE YggA)
B565_RS16055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B565_RS16065	COG0745	RESPONSE REGULATOR receiver
B565_RS16075	COG2198	Histidine kinase
B565_RS16075	COG0643	Histidine kinase
B565_RS16085	COG0835	chemotaxis
B565_RS16090	COG0840	transmembrane signaling receptor activity
B565_RS16100	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
B565_RS16105	COG2201	protein-glutamate methylesterase activity
B565_RS16110	COG1185	polyribonucleotide nucleotidyltransferase activity
B565_RS16115	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B565_RS16120	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B565_RS16125	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B565_RS16130	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B565_RS16135	COG0195	Participates in both transcription termination and antitermination
B565_RS16140	COG0779	Required for maturation of 30S ribosomal subunits
B565_RS16155	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B565_RS16160	COG0149	triose-phosphate isomerase activity
B565_RS16165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B565_RS16170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B565_RS16180	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B565_RS16185	COG1534	Rna-binding protein
B565_RS16200	COG1360	Flagellar Motor Protein
B565_RS16205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B565_RS16210	COG1722	exodeoxyribonuclease VII activity
B565_RS16215	COG0142	geranyltranstransferase activity
B565_RS16220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B565_RS16225	COG0737	Belongs to the 5'-nucleotidase family
B565_RS16245	COG2204	response regulator
B565_RS16250	COG0545	Peptidyl-prolyl cis-trans isomerase
B565_RS16260	COG2900	Belongs to the SlyX family
B565_RS16270	COG0601	transmembrane transport
B565_RS16285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B565_RS16290	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B565_RS16295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B565_RS16300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B565_RS16315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B565_RS16315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B565_RS16320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B565_RS16325	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B565_RS16335	COG0784	Response regulator, receiver
B565_RS16335	COG2198	Histidine kinase
B565_RS16335	COG2205	protein histidine kinase activity
B565_RS16340	COG1879	ABC-type sugar transport system periplasmic component
B565_RS16350	COG0745	RESPONSE REGULATOR receiver
B565_RS16355	COG3005	denitrification pathway
B565_RS16365	COG3381	protein complex oligomerization
B565_RS16385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B565_RS16390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B565_RS16395	COG0511	ligase activity, forming carbon-carbon bonds
B565_RS16400	COG0439	Biotin carboxylase
B565_RS16410	COG4145	pantothenate transmembrane transporter activity
B565_RS16415	COG1263	PTS System
B565_RS16415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B565_RS16415	COG2190	(PTS) system
B565_RS16420	COG0583	DNA-binding transcription factor activity
B565_RS16425	COG0604	alcohol dehydrogenase
B565_RS16430	COG2264	protein methyltransferase activity
B565_RS16435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B565_RS16440	COG0110	maltose O-acetyltransferase activity
B565_RS16445	COG0778	Nitroreductase
B565_RS16450	COG1902	pentaerythritol trinitrate reductase activity
B565_RS16450	COG0446	pyridine nucleotide-disulphide oxidoreductase
B565_RS16455	COG0616	signal peptide processing
B565_RS16475	COG0848	biopolymer transport protein
B565_RS16480	COG0811	peptide transport
B565_RS16485	COG0811	peptide transport
B565_RS16500	COG4174	ABC transporter (Permease)
B565_RS16505	COG4239	(ABC) transporter, permease
B565_RS16515	COG0444	Belongs to the ABC transporter superfamily
B565_RS16520	COG4608	Belongs to the ABC transporter superfamily
B565_RS16540	COG3416	Protein conserved in bacteria
B565_RS16550	COG0741	lytic transglycosylase activity
B565_RS16565	COG0488	(ABC) transporter
B565_RS16575	COG2252	PERMEase
B565_RS16580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B565_RS16585	COG0840	transmembrane signaling receptor activity
B565_RS16595	COG1278	Cold shock
B565_RS16615	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B565_RS16620	COG1162	GTPase activity
B565_RS16625	COG0688	phosphatidylethanolamine metabolic process
B565_RS16630	COG4628	conserved protein (DUF2132)
B565_RS16645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B565_RS16660	COG1073	alpha beta
B565_RS16665	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
B565_RS16670	COG2195	Cleaves the N-terminal amino acid of tripeptides
B565_RS16675	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B565_RS16680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B565_RS16685	COG3178	'Phosphotransferase
B565_RS16690	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B565_RS16695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B565_RS16700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B565_RS16705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B565_RS16710	COG2967	ApaG domain
B565_RS16715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B565_RS16725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B565_RS16730	COG3314	Sporulation integral membrane protein YlbJ
B565_RS16735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B565_RS16740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B565_RS16750	COG0142	geranyltranstransferase activity
B565_RS16755	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
B565_RS16760	COG0330	HflC and HflK could
B565_RS16765	COG0330	HflC and HflK could
B565_RS16770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B565_RS16775	COG1923	regulation of RNA biosynthetic process
B565_RS16780	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B565_RS16785	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B565_RS16790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B565_RS16800	COG0802	atpase or kinase
B565_RS16805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B565_RS16805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B565_RS16825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B565_RS16830	COG2011	ABC-type metal ion transport system permease component
B565_RS16835	COG1464	Belongs to the NlpA lipoprotein family
B565_RS16870	COG2198	Histidine kinase
B565_RS16870	COG5002	protein histidine kinase activity
B565_RS16870	COG0784	Response regulator, receiver
B565_RS16905	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B565_RS16910	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
B565_RS16915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B565_RS16920	COG2716	regulation of RNA biosynthetic process
B565_RS16925	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B565_RS16930	COG3013	Belongs to the UPF0304 family
B565_RS16940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B565_RS16945	COG0280	phosphate acetyltransferase
B565_RS16945	COG0857	belongs to the CobB CobQ family
B565_RS16950	COG1555	photosystem II stabilization
B565_RS16955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B565_RS16960	COG3104	oligopeptide transport
B565_RS16965	COG0745	RESPONSE REGULATOR receiver
B565_RS16995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B565_RS17010	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
B565_RS17045	COG0440	acetolactate synthase activity
B565_RS17050	COG0028	Belongs to the TPP enzyme family
B565_RS17060	COG0671	phosphoesterase, PA-phosphatase related
B565_RS17070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B565_RS17075	COG0473	3-isopropylmalate dehydrogenase activity
B565_RS17080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B565_RS17085	COG0066	3-isopropylmalate dehydratase activity
B565_RS17100	COG4143	(ABC) transporter
B565_RS17110	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
B565_RS17115	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B565_RS17165	COG0459	protein refolding
B565_RS17170	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B565_RS17175	COG0534	Mate efflux family protein
B565_RS17180	COG3030	protein affecting phage T7 exclusion by the F plasmid
B565_RS17185	COG1027	Aspartate ammonia-lyase
B565_RS17190	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B565_RS17195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B565_RS17200	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B565_RS17205	COG1610	YqeY-like protein
B565_RS17210	COG0358	DNA primase activity
B565_RS17215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B565_RS17235	COG0151	Belongs to the GarS family
B565_RS17240	COG0138	bifunctional purine biosynthesis protein purh
B565_RS17250	COG3036	rescue of stalled ribosome
B565_RS17255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B565_RS17260	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B565_RS17270	COG0673	inositol 2-dehydrogenase activity
B565_RS17280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B565_RS17285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B565_RS17295	COG0583	DNA-binding transcription factor activity
B565_RS17300	COG0477	Major facilitator Superfamily
B565_RS17315	COG1028	Short-chain dehydrogenase reductase Sdr
B565_RS17325	COG2425	protein containing a von Willebrand factor type A (vWA) domain
B565_RS17340	COG0456	acetyltransferase
B565_RS17350	COG1022	Amp-dependent synthetase and ligase
B565_RS17355	COG2918	glutathione biosynthetic process
B565_RS17360	COG0612	Peptidase, M16
B565_RS17365	COG1238	metal cluster binding
B565_RS17370	COG1064	alcohol dehydrogenase
B565_RS17390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B565_RS17395	COG0359	binds to the 23S rRNA
B565_RS17400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B565_RS17405	COG0360	Binds together with S18 to 16S ribosomal RNA
B565_RS17410	COG1914	H( )-stimulated, divalent metal cation uptake system
B565_RS17415	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B565_RS17425	COG0776	regulation of translation
B565_RS17440	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B565_RS17455	COG0560	Phosphoserine phosphatase
B565_RS17465	COG0813	purine-nucleoside phosphorylase activity
B565_RS17470	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B565_RS17475	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B565_RS17480	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B565_RS17490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B565_RS17495	COG0084	hydrolase, TatD family'
B565_RS17500	COG2165	general secretion pathway protein
B565_RS17505	COG1854	S-ribosylhomocysteine lyase activity
B565_RS17520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B565_RS17520	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B565_RS17560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B565_RS17565	COG1047	Peptidyl-prolyl cis-trans
B565_RS17570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B565_RS17575	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B565_RS17580	COG0196	riboflavin kinase activity
B565_RS17585	COG0728	peptidoglycan biosynthetic process
B565_RS17590	COG0268	Binds directly to 16S ribosomal RNA
B565_RS17595	COG0640	Transcriptional regulator
B565_RS17600	COG0583	DNA-binding transcription factor activity
B565_RS17610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B565_RS17615	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B565_RS17620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B565_RS17625	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
B565_RS17630	COG1051	belongs to the nudix hydrolase family
B565_RS17635	COG3066	DNA modification
B565_RS17645	COG0335	large ribosomal subunit rRNA binding
B565_RS17650	COG0336	Belongs to the RNA methyltransferase TrmD family
B565_RS17655	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B565_RS17660	COG0228	four-way junction DNA binding
B565_RS17665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B565_RS17670	COG4137	Cytochrome C assembly protein
B565_RS17675	COG4536	flavin adenine dinucleotide binding
B565_RS17685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B565_RS17685	COG1017	nitric oxide dioxygenase activity
B565_RS17690	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B565_RS17695	COG0039	L-malate dehydrogenase activity
B565_RS17700	COG4160	amino acid transport
B565_RS17705	COG4215	(ABC) transporter
B565_RS17710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B565_RS17715	COG1126	abc transporter atp-binding protein
B565_RS17720	COG1438	arginine binding
B565_RS17725	COG2837	iron assimilation
B565_RS17730	COG3842	ATPase activity
B565_RS17740	COG1840	ABC-type Fe3 transport system, periplasmic component
B565_RS17745	COG0347	Belongs to the P(II) protein family
B565_RS17765	COG3022	response to hydroperoxide
B565_RS17780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B565_RS17785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B565_RS17790	COG0762	integral membrane protein
B565_RS17795	COG1872	DUF167
B565_RS17805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B565_RS17810	COG0583	DNA-binding transcription factor activity
B565_RS17825	COG1929	Belongs to the glycerate kinase type-1 family
B565_RS17830	COG2610	gluconate transmembrane transporter activity
B565_RS17835	COG3835	regulator
B565_RS17840	COG3112	Uncharacterised protein family (UPF0231)
B565_RS17860	COG3568	Endonuclease Exonuclease Phosphatase
B565_RS17870	COG0513	Belongs to the DEAD box helicase family
B565_RS17910	COG1448	Aminotransferase
B565_RS17925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B565_RS17930	COG1328	CTP reductase activity
B565_RS17955	COG0633	Ferredoxin
B565_RS17955	COG0543	2 iron, 2 sulfur cluster binding
B565_RS17985	COG0840	transmembrane signaling receptor activity
B565_RS17990	COG3397	chitin binding
B565_RS17995	COG3174	membrane
B565_RS18000	COG0110	maltose O-acetyltransferase activity
B565_RS18015	COG1011	Hydrolase
B565_RS18020	COG0494	nUDIX hydrolase
B565_RS18025	COG1218	3'(2'),5'-bisphosphate nucleotidase
B565_RS18030	COG0814	amino acid
B565_RS18035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B565_RS18050	COG0626	cystathionine gamma-synthase activity
B565_RS18055	COG0460	homoserine dehydrogenase
B565_RS18055	COG0527	aspartate kinase activity
B565_RS18060	COG0306	phosphate transporter
B565_RS18065	COG1392	Phosphate transport regulator
B565_RS18075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B565_RS18080	COG2813	Specifically methylates the guanine in position
B565_RS18085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B565_RS18090	COG0297	glycogen (starch) synthase activity
B565_RS18130	COG1757	Na H antiporter
B565_RS18135	COG0316	Belongs to the HesB IscA family
B565_RS18145	COG0038	chloride channel
B565_RS18150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B565_RS18165	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B565_RS18165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B565_RS18195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B565_RS18200	COG0564	pseudouridine synthase activity
B565_RS18210	COG0110	maltose O-acetyltransferase activity
B565_RS18215	COG0366	Alpha amylase catalytic
B565_RS18220	COG1263	PTS System
B565_RS18220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B565_RS18240	COG0252	asparaginase activity
B565_RS18245	COG1253	flavin adenine dinucleotide binding
B565_RS18250	COG0586	Pfam SNARE associated Golgi protein
B565_RS18255	COG1686	Belongs to the peptidase S11 family
B565_RS18285	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B565_RS18290	COG0527	aspartate kinase activity
B565_RS18295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B565_RS18305	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B565_RS18310	COG1546	Belongs to the CinA family
B565_RS18315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B565_RS18320	COG4667	esterase of the alpha-beta hydrolase superfamily
B565_RS18330	COG1346	cytolysis
B565_RS18335	COG1380	Effector of murein hydrolase LrgA
B565_RS18340	COG0583	DNA-binding transcription factor activity
B565_RS18360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B565_RS18385	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B565_RS18390	COG2022	thiamine diphosphate biosynthetic process
B565_RS18400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B565_RS18405	COG0352	thiamine-phosphate diphosphorylase activity
B565_RS18410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B565_RS18430	COG0745	RESPONSE REGULATOR receiver
B565_RS18435	COG0642	Histidine kinase
B565_RS18440	COG0189	ligase activity
B565_RS18460	COG1757	Na H antiporter
B565_RS18465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B565_RS18495	COG0477	Major facilitator Superfamily
B565_RS18510	COG0312	modulator of DNA gyrase
B565_RS18515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B565_RS18525	COG3164	Protein of unknown function
B565_RS18530	COG1530	ribonuclease E activity
B565_RS18535	COG0424	maF-like protein
B565_RS18540	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B565_RS18545	COG1792	Involved in formation and maintenance of cell shape
B565_RS18550	COG1077	Cell shape determining protein MreB Mrl
B565_RS18575	COG4968	Prepilin-type N-terminal cleavage methylation domain
B565_RS18580	COG2165	general secretion pathway protein
B565_RS18595	COG1459	type II secretion system
B565_RS18600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B565_RS18645	COG2200	EAL domain
B565_RS18645	COG2199	diguanylate cyclase activity
B565_RS18650	COG2200	EAL domain
B565_RS18655	COG0387	Pfam Sodium calcium exchanger
B565_RS18660	COG2986	histidine ammonia-lyase
B565_RS18665	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B565_RS18670	COG0010	Belongs to the arginase family
B565_RS18675	COG1228	amidohydrolase
B565_RS18680	COG2188	Transcriptional regulator
B565_RS18685	COG0288	reversible hydration of carbon dioxide
B565_RS18695	COG2177	Part of the ABC transporter FtsEX involved in
B565_RS18700	COG2884	Cell division ATP-binding protein ftsE
B565_RS18705	COG0552	protein localization to endoplasmic reticulum
B565_RS18710	COG0742	ribosomal rna small subunit methyltransferase
B565_RS18735	COG2249	NAD(P)H dehydrogenase (quinone) activity
B565_RS18740	COG0583	DNA-binding transcription factor activity
B565_RS18745	COG4221	oxidoreductase activity
B565_RS18760	COG1770	oligopeptidase
B565_RS18775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B565_RS18780	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
B565_RS18790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B565_RS18800	COG2095	MarC family integral membrane protein
B565_RS18810	COG1301	dicarboxylic acid transport
B565_RS18835	COG3714	YhhN family
B565_RS18880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B565_RS18885	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B565_RS18890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B565_RS18895	COG0049	tRNA binding
B565_RS18900	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B565_RS18905	COG2168	tRNA wobble position uridine thiolation
B565_RS18910	COG2923	Belongs to the DsrF TusC family
B565_RS18915	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B565_RS18925	COG2964	Protein conserved in bacteria
B565_RS18930	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B565_RS18935	COG0085	RNA polymerase activity
B565_RS18940	COG0222	ribosome binding
B565_RS18945	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B565_RS18950	COG0081	regulation of translation
B565_RS18955	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B565_RS18960	COG0250	Participates in transcription elongation, termination and antitermination
B565_RS18975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B565_RS19000	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B565_RS19005	COG0569	domain protein
B565_RS19010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B565_RS19040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B565_RS19040	COG4191	Histidine kinase
B565_RS19045	COG3005	denitrification pathway
B565_RS19050	COG0243	molybdopterin cofactor binding
B565_RS19095	COG2204	response regulator
B565_RS19105	COG2205	protein histidine kinase activity
B565_RS19115	COG1028	Short-chain dehydrogenase reductase Sdr
B565_RS19120	COG0517	IMP dehydrogenase activity
B565_RS19120	COG0516	GMP reductase activity
B565_RS19125	COG5413	integral membrane protein
B565_RS19135	COG1522	sequence-specific DNA binding
B565_RS19140	COG2502	aspartate--ammonia ligase
B565_RS19145	COG0542	response to heat
B565_RS19155	COG0564	pseudouridine synthase activity
B565_RS19160	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B565_RS19165	COG0446	pyridine nucleotide-disulphide oxidoreductase
B565_RS19175	COG3681	Belongs to the UPF0597 family
B565_RS19180	COG2964	Protein conserved in bacteria
B565_RS19190	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B565_RS19195	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B565_RS19200	COG1979	alcohol dehydrogenase
B565_RS19205	COG2207	Transcriptional regulator
B565_RS19225	COG0583	DNA-binding transcription factor activity
B565_RS19240	COG0540	Belongs to the ATCase OTCase family
B565_RS19245	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
B565_RS19250	COG0531	amino acid
B565_RS19255	COG1982	Orn Lys Arg decarboxylase major
B565_RS19260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B565_RS19285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B565_RS19295	COG3078	GTPase activator activity
B565_RS19310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B565_RS19320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B565_RS19325	COG0408	coproporphyrinogen oxidase activity
B565_RS19330	COG0009	L-threonylcarbamoyladenylate synthase
B565_RS19340	COG0551	DNA topoisomerase type I activity
B565_RS19345	COG2922	Belongs to the Smg family
B565_RS19350	COG0758	DNA mediated transformation
B565_RS19355	COG1652	LysM domain
B565_RS19360	COG0242	peptide deformylase activity
B565_RS19365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B565_RS19370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B565_RS19370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B565_RS19375	COG0569	domain protein
B565_RS19380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B565_RS19385	COG1217	gtp-binding protein TYPA
B565_RS19390	COG0174	glutamine synthetase
B565_RS19405	COG2204	response regulator
B565_RS19410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B565_RS19435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B565_RS19440	COG0583	DNA-binding transcription factor activity
B565_RS19445	COG0519	Catalyzes the synthesis of GMP from XMP
B565_RS19445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B565_RS19455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B565_RS19460	COG1396	sequence-specific DNA binding
B565_RS19465	COG1012	belongs to the aldehyde dehydrogenase family
B565_RS19470	COG2962	Rard protein
B565_RS19475	COG0840	transmembrane signaling receptor activity
B565_RS19480	COG2391	methyltransferase activity
B565_RS19495	COG0129	dihydroxy-acid dehydratase activity
B565_RS19505	COG3978	acetolactate synthase activity
B565_RS19515	COG0606	chelatase, subunit chli
B565_RS19520	COG0204	Acyl-transferase
B565_RS19525	COG0204	Acyl-transferase
B565_RS19530	COG1683	Conserved Protein
B565_RS19540	COG1335	isochorismatase
B565_RS19550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B565_RS19555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B565_RS19565	COG3084	Protein conserved in bacteria
B565_RS19570	COG4251	negative regulation of phosphorylation
B565_RS19570	COG5001	Diguanylate cyclase
B565_RS19570	COG3706	GGDEF domain
B565_RS19570	COG2203	Gaf domain
B565_RS19585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B565_RS19590	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B565_RS19595	COG1561	YicC-like family, N-terminal region
B565_RS19600	COG0583	DNA-binding transcription factor activity
B565_RS19620	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B565_RS19625	COG0385	Bile acid
B565_RS19630	COG0531	amino acid
B565_RS19635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B565_RS19640	COG0531	amino acid
B565_RS19650	COG2731	YhcH YjgK YiaL family protein
B565_RS19655	COG3250	beta-galactosidase activity
B565_RS19660	COG1609	Transcriptional regulator
B565_RS19700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B565_RS19705	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B565_RS19705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B565_RS19710	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
B565_RS19715	COG3074	FtsZ-dependent cytokinesis
B565_RS19725	COG1045	serine acetyltransferase
B565_RS19735	COG0745	RESPONSE REGULATOR receiver
B565_RS19740	COG2205	protein histidine kinase activity
B565_RS19745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B565_RS19750	COG0534	Mate efflux family protein
B565_RS19765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B565_RS19770	COG2937	Belongs to the GPAT DAPAT family
B565_RS19775	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B565_RS19780	COG3161	chorismate lyase activity
B565_RS19795	COG0604	alcohol dehydrogenase
B565_RS19800	COG1609	Transcriptional regulator
B565_RS19805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B565_RS19820	COG1519	Transferase
B565_RS19825	COG0859	PFAM glycosyl transferase family 9
B565_RS19830	COG0463	Glycosyl transferase, family 2
B565_RS19835	COG0859	PFAM glycosyl transferase family 9
B565_RS19840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B565_RS19845	COG2990	Protein conserved in bacteria
B565_RS19850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B565_RS19860	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B565_RS19865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B565_RS19870	COG2003	Belongs to the UPF0758 family
B565_RS19875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B565_RS19880	COG0756	dUTP diphosphatase activity
B565_RS19885	COG4974	Belongs to the 'phage' integrase family
B565_RS19910	COG2916	Histone family protein nucleoid-structuring protein H-NS
B565_RS19940	COG0756	dUTP diphosphatase activity
B565_RS19945	COG0756	dUTP diphosphatase activity
B565_RS19950	COG1309	transcriptional regulator
B565_RS19955	COG0668	transmembrane transport
B565_RS19960	COG0166	Belongs to the GPI family
B565_RS19965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B565_RS19985	COG0045	succinate-CoA ligase (ADP-forming) activity
B565_RS19985	COG1042	CoA-binding domain protein
B565_RS19985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B565_RS20020	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
B565_RS20025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B565_RS20030	COG1739	Uncharacterized protein family UPF0029
B565_RS20035	COG0006	proline dipeptidase activity
B565_RS20040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B565_RS20045	COG1024	Enoyl-CoA hydratase
B565_RS20045	COG1250	3-hydroxyacyl-CoA dehydrogenase
B565_RS20050	COG0183	Belongs to the thiolase family
B565_RS20075	COG0425	Belongs to the sulfur carrier protein TusA family
B565_RS20080	COG0251	oxidation-reduction process
B565_RS20085	COG2885	chlorophyll binding
B565_RS20090	COG2818	Glycosylase
B565_RS20095	COG0752	glycyl-tRNA synthetase alpha subunit
B565_RS20100	COG0751	glycine-tRNA ligase activity
B565_RS20110	COG2202	Pas domain
B565_RS20110	COG2200	EAL domain
B565_RS20110	COG2199	diguanylate cyclase activity
B565_RS20120	COG0840	transmembrane signaling receptor activity
B565_RS20125	COG2188	Transcriptional regulator
B565_RS20140	COG1609	Transcriptional regulator
B565_RS20170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B565_RS20185	COG2960	long-chain fatty acid transporting porin activity
B565_RS20190	COG5001	Diguanylate cyclase
B565_RS20200	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B565_RS20215	COG3118	belongs to the thioredoxin family
B565_RS20220	COG0513	Belongs to the DEAD box helicase family
B565_RS20225	COG0248	Ppx GppA phosphatase
B565_RS20235	COG0742	ribosomal rna small subunit methyltransferase
B565_RS20255	COG3469	chitinase activity
B565_RS20270	COG0084	hydrolase, TatD family'
B565_RS20275	COG0805	protein transport
B565_RS20280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B565_RS20285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B565_RS20290	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B565_RS20295	COG3165	ubiquinone biosynthetic process from chorismate
B565_RS20300	COG2226	methyltransferase
B565_RS20305	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B565_RS20310	COG0402	S-adenosylhomocysteine deaminase activity
B565_RS20315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B565_RS20350	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
B565_RS20355	COG0848	biopolymer transport protein
B565_RS20360	COG0811	peptide transport
B565_RS20365	COG0811	peptide transport
B565_RS20375	COG2771	luxR family
B565_RS20380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B565_RS20385	COG1349	DNA-binding transcription factor activity
B565_RS20390	COG0745	RESPONSE REGULATOR receiver
B565_RS20395	COG2205	protein histidine kinase activity
B565_RS20410	COG4452	Inner membrane protein CreD
B565_RS20415	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B565_RS20420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B565_RS20425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B565_RS20430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B565_RS20435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B565_RS20440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B565_RS20445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B565_RS20455	COG0356	it plays a direct role in the translocation of protons across the membrane
B565_RS20465	COG1475	DNA binding
B565_RS20470	COG1192	Involved in chromosome partitioning
B565_RS20475	COG0357	Ribosomal RNA small subunit methyltransferase G
B565_RS20480	COG0445	tRNA wobble uridine modification
B565_RS20485	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B565_RS20495	COG4615	Cyclic peptide transporter
B565_RS20500	COG1120	ATPase activity
B565_RS20505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B565_RS20510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B565_RS20515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B565_RS20520	COG0706	membrane insertase activity
B565_RS20525	COG0594	ribonuclease P activity
B565_RS20530	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B565_RS20535	COG1126	abc transporter atp-binding protein