locus-tag	class	description
FOB40_RS00015	COG1309	transcriptional regulator
FOB40_RS00020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB40_RS00025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB40_RS00035	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOB40_RS00070	COG0463	Glycosyl transferase, family 2
FOB40_RS00090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB40_RS00100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB40_RS00120	COG1216	Glycosyl transferase, family 2
FOB40_RS00135	COG0438	transferase activity, transferring glycosyl groups
FOB40_RS00140	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FOB40_RS00145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB40_RS00155	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOB40_RS00155	COG0662	Cupin 2, conserved barrel domain protein
FOB40_RS00175	COG1596	polysaccharide export
FOB40_RS00180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOB40_RS00185	COG0489	protein tyrosine kinase activity
FOB40_RS00185	COG3206	protein involved in exopolysaccharide biosynthesis
FOB40_RS00205	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB40_RS00225	COG0577	efflux transmembrane transporter activity
FOB40_RS00225	COG1136	(ABC) transporter
FOB40_RS00230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB40_RS00235	COG1227	inorganic diphosphatase activity
FOB40_RS00240	COG0497	DNA recombination
FOB40_RS00245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOB40_RS00250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOB40_RS00255	COG0443	Heat shock 70 kDa protein
FOB40_RS00260	COG0484	heat shock protein binding
FOB40_RS00290	COG1285	pathogenesis
FOB40_RS00300	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB40_RS00320	COG2391	methyltransferase activity
FOB40_RS00330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB40_RS00335	COG1566	PFAM secretion protein HlyD family protein
FOB40_RS00340	COG0577	efflux transmembrane transporter activity
FOB40_RS00340	COG1136	(ABC) transporter
FOB40_RS00345	COG1136	(ABC) transporter
FOB40_RS00345	COG0577	efflux transmembrane transporter activity
FOB40_RS00350	COG0577	efflux transmembrane transporter activity
FOB40_RS00350	COG1136	(ABC) transporter
FOB40_RS00360	COG0095	Lipoate-protein ligase
FOB40_RS00370	COG0702	epimerase
FOB40_RS00375	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB40_RS00405	COG4964	Belongs to the GSP D family
FOB40_RS00415	COG2894	cell division
FOB40_RS00455	COG1454	alcohol dehydrogenase
FOB40_RS00465	COG0564	pseudouridine synthase activity
FOB40_RS00495	COG1280	lysine exporter protein (LysE YggA)
FOB40_RS00510	COG3263	regulation of cellular component size
FOB40_RS00520	COG1876	peptidase activity
FOB40_RS00525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB40_RS00530	COG1393	Belongs to the ArsC family
FOB40_RS00540	COG3069	C4-dicarboxylate transmembrane transporter activity
FOB40_RS00545	COG1473	amidohydrolase
FOB40_RS00555	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOB40_RS00565	COG0017	Asparaginyl-tRNA synthetase
FOB40_RS00580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB40_RS00585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOB40_RS00590	COG0156	8-amino-7-oxononanoate synthase activity
FOB40_RS00595	COG2226	methyltransferase
FOB40_RS00595	COG1073	alpha beta
FOB40_RS00600	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOB40_RS00605	COG0501	Belongs to the peptidase M48B family
FOB40_RS00615	COG0633	Ferredoxin
FOB40_RS00615	COG3217	Mosc domain protein beta barrel domain protein
FOB40_RS00615	COG0633	Ferredoxin
FOB40_RS00615	COG3217	Mosc domain protein beta barrel domain protein
FOB40_RS00630	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOB40_RS00630	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOB40_RS00630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOB40_RS00630	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FOB40_RS00640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB40_RS00645	COG1607	acyl-coa hydrolase
FOB40_RS00655	COG3021	interspecies interaction between organisms
FOB40_RS00660	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB40_RS00665	COG2027	D-alanyl-D-alanine carboxypeptidase
FOB40_RS00670	COG1061	Type III restriction enzyme res subunit
FOB40_RS00675	COG1566	PFAM secretion protein HlyD family protein
FOB40_RS00685	COG1966	Carbon starvation protein
FOB40_RS00690	COG3279	Response regulator of the LytR AlgR family
FOB40_RS00695	COG3275	phosphorelay sensor kinase activity
FOB40_RS00700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOB40_RS00700	COG2199	diguanylate cyclase activity
FOB40_RS00710	COG1940	carbohydrate kinase activity
FOB40_RS00710	COG1846	Transcriptional regulator
FOB40_RS00715	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOB40_RS00720	COG0363	glucosamine-6-phosphate deaminase activity
FOB40_RS00725	COG1263	PTS System
FOB40_RS00725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB40_RS00725	COG2190	(PTS) system
FOB40_RS00735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB40_RS00740	COG0735	belongs to the Fur family
FOB40_RS00750	COG0716	FMN binding
FOB40_RS00765	COG0596	Alpha beta hydrolase
FOB40_RS00770	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FOB40_RS00775	COG0033	Phosphoglucomutase
FOB40_RS00790	COG2951	lytic endotransglycosylase activity
FOB40_RS00795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOB40_RS00800	COG4136	ATPase activity
FOB40_RS00810	COG4134	Bacterial extracellular solute-binding protein
FOB40_RS00820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB40_RS00830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB40_RS00840	COG0729	surface antigen
FOB40_RS00845	COG2911	Protein conserved in bacteria
FOB40_RS00865	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOB40_RS00875	COG0741	lytic transglycosylase activity
FOB40_RS00885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB40_RS00890	COG4771	TonB-dependent receptor
FOB40_RS00895	COG1169	isochorismate synthase
FOB40_RS00900	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOB40_RS00905	COG3433	isochorismatase activity
FOB40_RS00905	COG1535	isochorismatase
FOB40_RS00910	COG1028	Short-chain dehydrogenase reductase Sdr
FOB40_RS00915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOB40_RS00915	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FOB40_RS00940	COG1278	Cold shock
FOB40_RS00965	COG4166	transmembrane transport
FOB40_RS00970	COG1349	DNA-binding transcription factor activity
FOB40_RS00975	COG1882	Formate acetyltransferase
FOB40_RS00980	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB40_RS00985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB40_RS00995	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOB40_RS01010	COG4166	transmembrane transport
FOB40_RS01015	COG0622	Phosphoesterase
FOB40_RS01030	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FOB40_RS01035	COG0784	Response regulator, receiver
FOB40_RS01035	COG0835	chemotaxis
FOB40_RS01040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOB40_RS01045	COG1815	bacterial-type flagellum-dependent cell motility
FOB40_RS01065	COG4787	bacterial-type flagellum-dependent cell motility
FOB40_RS01075	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FOB40_RS01080	COG1706	bacterial-type flagellum-dependent cell motility
FOB40_RS01085	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB40_RS01085	COG3951	Flagellar rod assembly protein muramidase FlgJ
FOB40_RS01095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB40_RS01100	COG2239	Acts as a magnesium transporter
FOB40_RS01110	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOB40_RS01115	COG2716	regulation of RNA biosynthetic process
FOB40_RS01140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOB40_RS01145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOB40_RS01150	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOB40_RS01155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOB40_RS01175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOB40_RS01185	COG0590	tRNA wobble adenosine to inosine editing
FOB40_RS01190	COG0573	inorganic phosphate transmembrane transporter activity
FOB40_RS01195	COG0581	inorganic phosphate transmembrane transporter activity
FOB40_RS01200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB40_RS01205	COG0704	Plays a role in the regulation of phosphate uptake
FOB40_RS01210	COG1253	flavin adenine dinucleotide binding
FOB40_RS01225	COG0531	amino acid
FOB40_RS01240	COG1126	abc transporter atp-binding protein
FOB40_RS01245	COG0765	amino acid transport
FOB40_RS01250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB40_RS01255	COG3706	GGDEF domain
FOB40_RS01260	COG2271	Major facilitator Superfamily
FOB40_RS01270	COG2197	response regulator
FOB40_RS01275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB40_RS01295	COG1785	Belongs to the alkaline phosphatase family
FOB40_RS01300	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOB40_RS01305	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOB40_RS01315	COG1199	ATP-dependent helicase activity
FOB40_RS01325	COG2801	Transposase and inactivated derivatives
FOB40_RS01365	COG0346	lactoylglutathione lyase activity
FOB40_RS01370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOB40_RS01375	COG4660	Part of a membrane complex involved in electron transport
FOB40_RS01380	COG4659	FMN binding
FOB40_RS01385	COG4658	electron transport chain
FOB40_RS01395	COG2878	Part of a membrane complex involved in electron transport
FOB40_RS01400	COG4657	Part of a membrane complex involved in electron transport
FOB40_RS01420	COG0346	lactoylglutathione lyase activity
FOB40_RS01430	COG1187	pseudouridine synthase activity
FOB40_RS01435	COG2807	transmembrane transport
FOB40_RS01445	COG0583	DNA-binding transcription factor activity
FOB40_RS01460	COG2979	Protein of unknown function (DUF533)
FOB40_RS01470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB40_RS01480	COG1294	oxidase, subunit
FOB40_RS01515	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB40_RS01520	COG2814	Major facilitator Superfamily
FOB40_RS01530	COG0656	L-ascorbic acid biosynthetic process
FOB40_RS01555	COG0583	DNA-binding transcription factor activity
FOB40_RS01565	COG0840	transmembrane signaling receptor activity
FOB40_RS01570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOB40_RS01575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB40_RS01580	COG2271	Major facilitator Superfamily
FOB40_RS01585	COG1349	DNA-binding transcription factor activity
FOB40_RS01595	COG0584	glycerophosphoryl diester phosphodiesterase
FOB40_RS01600	COG4574	serine-type endopeptidase inhibitor activity
FOB40_RS01605	COG3085	chromosome segregation
FOB40_RS01610	COG0583	DNA-binding transcription factor activity
FOB40_RS01620	COG1448	Aminotransferase
FOB40_RS01635	COG0658	competence protein
FOB40_RS01635	COG2333	competence protein COMEC
FOB40_RS01645	COG1663	tetraacyldisaccharide 4'-kinase activity
FOB40_RS01650	COG2835	tetraacyldisaccharide 4'-kinase activity
FOB40_RS01655	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOB40_RS01660	COG2197	response regulator
FOB40_RS01665	COG0322	excinuclease ABC activity
FOB40_RS01840	COG4695	Portal protein
FOB40_RS01845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOB40_RS01850	COG2194	sulfuric ester hydrolase activity
FOB40_RS01955	COG4974	Belongs to the 'phage' integrase family
FOB40_RS01965	COG0367	asparagine synthase
FOB40_RS01975	COG4651	solute:proton antiporter activity
FOB40_RS01975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB40_RS01980	COG0647	UMP catabolic process
FOB40_RS01995	COG1902	pentaerythritol trinitrate reductase activity
FOB40_RS02000	COG1253	flavin adenine dinucleotide binding
FOB40_RS02010	COG0277	FAD linked oxidase domain protein
FOB40_RS02010	COG0247	lactate metabolic process
FOB40_RS02020	COG2050	protein possibly involved in aromatic compounds catabolism
FOB40_RS02035	COG5001	Diguanylate cyclase
FOB40_RS02035	COG3300	MHYT domain
FOB40_RS02040	COG2056	Na+-H+ antiporter family
FOB40_RS02045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB40_RS02050	COG0671	phosphoesterase, PA-phosphatase related
FOB40_RS02055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB40_RS02060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB40_RS02070	COG0101	tRNA pseudouridine synthase activity
FOB40_RS02075	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOB40_RS02080	COG0285	dihydrofolate synthase activity
FOB40_RS02085	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FOB40_RS02090	COG0393	Putative heavy-metal-binding
FOB40_RS02100	COG1648	precorrin-2 dehydrogenase activity
FOB40_RS02100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB40_RS02120	COG4667	esterase of the alpha-beta hydrolase superfamily
FOB40_RS02125	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOB40_RS02130	COG1368	sulfuric ester hydrolase activity
FOB40_RS02140	COG0527	aspartate kinase activity
FOB40_RS02145	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOB40_RS02145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB40_RS02150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB40_RS02170	COG0596	Alpha beta hydrolase
FOB40_RS02190	COG0577	efflux transmembrane transporter activity
FOB40_RS02195	COG1136	(ABC) transporter
FOB40_RS02210	COG2814	Major facilitator Superfamily
FOB40_RS02230	COG0672	)-iron permease
FOB40_RS02325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB40_RS02340	COG0659	secondary active sulfate transmembrane transporter activity
FOB40_RS02355	COG0392	lysyltransferase activity
FOB40_RS02355	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOB40_RS02365	COG2205	protein histidine kinase activity
FOB40_RS02370	COG0745	RESPONSE REGULATOR receiver
FOB40_RS02390	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOB40_RS02395	COG1278	Cold shock
FOB40_RS02400	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOB40_RS02405	COG0542	response to heat
FOB40_RS02410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOB40_RS02415	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FOB40_RS02420	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FOB40_RS02425	COG3134	Outer membrane lipoprotein
FOB40_RS02430	COG3706	GGDEF domain
FOB40_RS02435	COG0492	ferredoxin-NADP+ reductase activity
FOB40_RS02440	COG0686	Belongs to the AlaDH PNT family
FOB40_RS02450	COG1674	ftsk spoiiie
FOB40_RS02450	COG0531	amino acid
FOB40_RS02455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOB40_RS02460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOB40_RS02465	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOB40_RS02470	COG1286	toxin biosynthetic process
FOB40_RS02475	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOB40_RS02485	COG0563	adenylate kinase activity
FOB40_RS02490	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOB40_RS02500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB40_RS02515	COG5001	Diguanylate cyclase
FOB40_RS02515	COG3300	MHYT domain
FOB40_RS02565	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOB40_RS02570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOB40_RS02575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB40_RS02590	COG0513	Belongs to the DEAD box helicase family
FOB40_RS02595	COG0386	Belongs to the glutathione peroxidase family
FOB40_RS02605	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB40_RS02610	COG0383	alpha-mannosidase activity
FOB40_RS02615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB40_RS02615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB40_RS02615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB40_RS02620	COG2188	Transcriptional regulator
FOB40_RS02625	COG1570	exodeoxyribonuclease VII activity
FOB40_RS02630	COG3038	cytochrome b561
FOB40_RS02635	COG0516	GMP reductase activity
FOB40_RS02635	COG0517	IMP dehydrogenase activity
FOB40_RS02640	COG0519	Catalyzes the synthesis of GMP from XMP
FOB40_RS02640	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOB40_RS02675	COG1025	Belongs to the peptidase M16 family
FOB40_RS02680	COG2062	phosphohistidine phosphatase, SixA
FOB40_RS02690	COG0697	spore germination
FOB40_RS02695	COG4166	transmembrane transport
FOB40_RS02700	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOB40_RS02705	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOB40_RS02715	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB40_RS02720	COG1136	(ABC) transporter
FOB40_RS02725	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB40_RS02730	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FOB40_RS02745	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOB40_RS02750	COG0740	serine-type endopeptidase activity
FOB40_RS02755	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOB40_RS02760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOB40_RS02765	COG0776	regulation of translation
FOB40_RS02770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB40_RS02775	COG0488	(ABC) transporter
FOB40_RS02780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB40_RS02785	COG3162	membrane
FOB40_RS02800	COG1024	Enoyl-CoA hydratase
FOB40_RS02805	COG1115	amino acid carrier protein
FOB40_RS02810	COG0456	acetyltransferase
FOB40_RS02830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB40_RS02840	COG3842	ATPase activity
FOB40_RS02845	COG1840	ABC-type Fe3 transport system, periplasmic component
FOB40_RS02855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOB40_RS02860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB40_RS02865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB40_RS02880	COG3088	subunit of a heme lyase
FOB40_RS02880	COG4235	cytochrome complex assembly
FOB40_RS02890	COG1138	Cytochrome C-type biogenesis protein
FOB40_RS02895	COG3301	Polysulphide reductase, NrfD
FOB40_RS02900	COG0437	4 iron, 4 sulfur cluster binding
FOB40_RS02905	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FOB40_RS02920	COG0247	lactate metabolic process
FOB40_RS02925	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FOB40_RS02930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOB40_RS02935	COG3012	SEC-C Motif Domain Protein
FOB40_RS02940	COG0840	transmembrane signaling receptor activity
FOB40_RS02945	COG1846	Transcriptional regulator
FOB40_RS02945	COG1940	carbohydrate kinase activity
FOB40_RS02950	COG3148	PFAM DTW domain containing protein
FOB40_RS02955	COG0730	response to heat
FOB40_RS02960	COG0583	DNA-binding transcription factor activity
FOB40_RS02975	COG3593	DNA synthesis involved in DNA repair
FOB40_RS03025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOB40_RS03030	COG1011	Hydrolase
FOB40_RS03045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB40_RS03050	COG2832	Protein of unknown function (DUF454)
FOB40_RS03055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB40_RS03065	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOB40_RS03075	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOB40_RS03090	COG1560	Kdo2-lipid A biosynthetic process
FOB40_RS03095	COG1560	Kdo2-lipid A biosynthetic process
FOB40_RS03120	COG0417	DNA replication proofreading
FOB40_RS03135	COG1451	nucleotide metabolic process
FOB40_RS03150	COG3069	C4-dicarboxylate transmembrane transporter activity
FOB40_RS03165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB40_RS03165	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOB40_RS03170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB40_RS03175	COG2985	domain, Protein
FOB40_RS03175	COG0569	domain protein
FOB40_RS03190	COG0556	nucleotide-excision repair
FOB40_RS03200	COG0586	Pfam SNARE associated Golgi protein
FOB40_RS03205	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOB40_RS03210	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB40_RS03225	COG4681	YaeQ
FOB40_RS03240	COG3829	transcription factor binding
FOB40_RS03270	COG0534	Mate efflux family protein
FOB40_RS03285	COG0307	riboflavin synthase, alpha
FOB40_RS03295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB40_RS03300	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOB40_RS03305	COG0697	spore germination
FOB40_RS03310	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOB40_RS03350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB40_RS03355	COG3099	Belongs to the UPF0263 family
FOB40_RS03360	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FOB40_RS03365	COG2894	cell division
FOB40_RS03370	COG0850	regulation of cytokinetic process
FOB40_RS03375	COG3100	YcgL domain-containing protein
FOB40_RS03380	COG1760	l-serine dehydratase
FOB40_RS03390	COG1760	l-serine dehydratase
FOB40_RS03395	COG3123	guanosine phosphorylase activity
FOB40_RS03405	COG0205	6-phosphofructokinase activity
FOB40_RS03415	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOB40_RS03420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB40_RS03430	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FOB40_RS03435	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FOB40_RS03445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOB40_RS03455	COG0242	peptide deformylase activity
FOB40_RS03490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOB40_RS03495	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOB40_RS03500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB40_RS03510	COG0549	Belongs to the carbamate kinase family
FOB40_RS03525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB40_RS03530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB40_RS03535	COG0697	spore germination
FOB40_RS03540	COG3608	succinylglutamate desuccinylase aspartoacylase
FOB40_RS03540	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FOB40_RS03545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOB40_RS03550	COG2068	MobA-Related Protein
FOB40_RS03555	COG0493	'glutamate synthase
FOB40_RS03555	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB40_RS03560	COG0402	S-adenosylhomocysteine deaminase activity
FOB40_RS03565	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FOB40_RS03570	COG2080	2 iron, 2 sulfur cluster binding
FOB40_RS03570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FOB40_RS03575	COG2233	PERMEase
FOB40_RS03580	COG0402	S-adenosylhomocysteine deaminase activity
FOB40_RS03585	COG2252	PERMEase
FOB40_RS03590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FOB40_RS03595	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FOB40_RS03600	COG2080	2 iron, 2 sulfur cluster binding
FOB40_RS03605	COG3134	Outer membrane lipoprotein
FOB40_RS03615	COG1288	antiporter activity
FOB40_RS03620	COG0318	PFAM AMP-dependent synthetase and ligase
FOB40_RS03625	COG2199	diguanylate cyclase activity
FOB40_RS03640	COG0107	imidazoleglycerol-phosphate synthase activity
FOB40_RS03645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOB40_RS03650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOB40_RS03655	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOB40_RS03655	COG0131	Imidazoleglycerol-phosphate dehydratase
FOB40_RS03660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOB40_RS03665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOB40_RS03670	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOB40_RS03680	COG1199	ATP-dependent helicase activity
FOB40_RS03685	COG1214	PFAM Peptidase M22, glycoprotease
FOB40_RS03695	COG2267	carboxylic ester hydrolase activity
FOB40_RS03700	COG0318	PFAM AMP-dependent synthetase and ligase
FOB40_RS03710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB40_RS03715	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FOB40_RS03720	COG0709	Synthesizes selenophosphate from selenide and ATP
FOB40_RS03735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOB40_RS03740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOB40_RS03745	COG0840	transmembrane signaling receptor activity
FOB40_RS03750	COG1254	Belongs to the acylphosphatase family
FOB40_RS03760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB40_RS03760	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB40_RS03765	COG0489	protein tyrosine kinase activity
FOB40_RS03770	COG0572	uridine kinase
FOB40_RS03775	COG0717	Belongs to the dCTP deaminase family
FOB40_RS03780	COG0306	phosphate transporter
FOB40_RS03785	COG2140	Oxalate decarboxylase
FOB40_RS03790	COG1609	Transcriptional regulator
FOB40_RS03805	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB40_RS03805	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB40_RS03810	COG3715	PTS system
FOB40_RS03815	COG3716	PTS system mannose fructose sorbose family IID component
FOB40_RS03820	COG2942	2-epimerase
FOB40_RS03825	COG3313	Fe-S protein
FOB40_RS03830	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FOB40_RS03835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB40_RS03840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB40_RS03845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB40_RS03855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB40_RS03865	COG0366	Alpha amylase catalytic
FOB40_RS03880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOB40_RS03885	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOB40_RS03890	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOB40_RS03895	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOB40_RS03900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOB40_RS03905	COG0072	phenylalanine-tRNA ligase activity
FOB40_RS03905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB40_RS03910	COG0776	regulation of translation
FOB40_RS03915	COG2205	protein histidine kinase activity
FOB40_RS03915	COG0784	Response regulator, receiver
FOB40_RS03940	COG3300	MHYT domain
FOB40_RS03940	COG5001	Diguanylate cyclase
FOB40_RS03945	COG1609	Transcriptional regulator
FOB40_RS03950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB40_RS03955	COG1879	ABC-type sugar transport system periplasmic component
FOB40_RS03960	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB40_RS03965	COG1129	ABC transporter
FOB40_RS03970	COG1869	D-ribose catabolic process
FOB40_RS03975	COG0625	glutathione transferase activity
FOB40_RS03990	COG1177	transmembrane transport
FOB40_RS04015	COG0037	tRNA processing
FOB40_RS04020	COG0589	response to stress
FOB40_RS04025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB40_RS04040	COG2217	Heavy metal translocating P-type atpase
FOB40_RS04050	COG2010	Cytochrome c
FOB40_RS04065	COG3278	Belongs to the heme-copper respiratory oxidase family
FOB40_RS04075	COG1956	GAF domain-containing protein
FOB40_RS04080	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FOB40_RS04090	COG0308	aminopeptidase N
FOB40_RS04100	COG2902	Dehydrogenase
FOB40_RS04105	COG0167	dihydroorotate dehydrogenase activity
FOB40_RS04120	COG0254	rRNA binding
FOB40_RS04125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOB40_RS04130	COG0116	Belongs to the methyltransferase superfamily
FOB40_RS04130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOB40_RS04140	COG0488	(ABC) transporter
FOB40_RS04150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB40_RS04155	COG1067	ATP-dependent peptidase activity
FOB40_RS04180	COG3141	response to X-ray
FOB40_RS04185	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FOB40_RS04190	COG4221	oxidoreductase activity
FOB40_RS04235	COG0372	Belongs to the citrate synthase family
FOB40_RS04240	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOB40_RS04250	COG2995	paraquat-inducible protein a
FOB40_RS04255	COG3008	intermembrane lipid transfer
FOB40_RS04260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB40_RS04260	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FOB40_RS04275	COG0084	hydrolase, TatD family'
FOB40_RS04280	COG0470	DNA polymerase III
FOB40_RS04285	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOB40_RS04290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOB40_RS04295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB40_RS04300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB40_RS04305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB40_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
FOB40_RS04320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB40_RS04325	COG0416	fatty acid biosynthetic process
FOB40_RS04330	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOB40_RS04335	COG1399	metal-binding, possibly nucleic acid-binding protein
FOB40_RS04340	COG0424	maF-like protein
FOB40_RS04355	COG1530	ribonuclease E activity
FOB40_RS04360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB40_RS04360	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FOB40_RS04360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB40_RS04365	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB40_RS04370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB40_RS04370	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB40_RS04375	COG1609	Transcriptional regulator
FOB40_RS04380	COG0814	amino acid
FOB40_RS04390	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FOB40_RS04400	COG0513	Belongs to the DEAD box helicase family
FOB40_RS04410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOB40_RS04415	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB40_RS04420	COG2840	Smr protein MutS2
FOB40_RS04425	COG3706	GGDEF domain
FOB40_RS04430	COG0406	alpha-ribazole phosphatase activity
FOB40_RS04445	COG2824	Alkylphosphonate utilization operon protein PhnA
FOB40_RS04460	COG0494	nUDIX hydrolase
FOB40_RS04465	COG0814	amino acid
FOB40_RS04475	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FOB40_RS04480	COG0514	ATP-dependent DNA helicase (RecQ)
FOB40_RS04485	COG2766	serine protein kinase
FOB40_RS04490	COG2718	Belongs to the UPF0229 family
FOB40_RS04495	COG2719	SpoVR family
FOB40_RS04500	COG1024	Enoyl-CoA hydratase
FOB40_RS04500	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB40_RS04505	COG0183	Belongs to the thiolase family
FOB40_RS04510	COG0714	Associated with various cellular activities
FOB40_RS04530	COG2304	oxidoreductase activity
FOB40_RS04540	COG1595	DNA-templated transcription, initiation
FOB40_RS04550	COG2067	long-chain fatty acid transport protein
FOB40_RS04555	COG2067	long-chain fatty acid transport protein
FOB40_RS04560	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FOB40_RS04575	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOB40_RS04585	COG1643	Atp-dependent helicase
FOB40_RS04590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOB40_RS04590	COG0617	tRNA 3'-terminal CCA addition
FOB40_RS04590	COG0517	IMP dehydrogenase activity
FOB40_RS04595	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOB40_RS04600	COG3119	arylsulfatase activity
FOB40_RS04605	COG0714	Associated with various cellular activities
FOB40_RS04620	COG2304	oxidoreductase activity
FOB40_RS04625	COG2304	oxidoreductase activity
FOB40_RS04650	COG0641	radical SAM
FOB40_RS04695	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOB40_RS04700	COG3457	Alanine racemase
FOB40_RS04715	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FOB40_RS04725	COG2188	Transcriptional regulator
FOB40_RS04735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB40_RS04780	COG2925	Exonuclease
FOB40_RS04790	COG3345	alpha-galactosidase
FOB40_RS04795	COG1380	Effector of murein hydrolase LrgA
FOB40_RS04800	COG1346	cytolysis
FOB40_RS04805	COG0295	cytidine deaminase activity
FOB40_RS04810	COG3033	Beta-eliminating lyase
FOB40_RS04820	COG3046	protein related to deoxyribodipyrimidine photolyase
FOB40_RS04825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB40_RS04830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB40_RS04855	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB40_RS04865	COG3158	transport of potassium into the cell
FOB40_RS04870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB40_RS04875	COG0651	ATP synthesis coupled electron transport
FOB40_RS04880	COG0650	Formate hydrogenlyase subunit 4
FOB40_RS04885	COG3261	NADH dehydrogenase
FOB40_RS04885	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FOB40_RS04890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB40_RS04895	COG3260	NADH ubiquinone oxidoreductase 20
FOB40_RS04905	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOB40_RS04915	COG1921	L-seryl-tRNASec selenium transferase activity
FOB40_RS04925	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOB40_RS04930	COG0298	carbon dioxide binding
FOB40_RS04940	COG0309	Hydrogenase expression formation protein (HypE)
FOB40_RS04945	COG0375	protein maturation
FOB40_RS04950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FOB40_RS04965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB40_RS04970	COG0601	transmembrane transport
FOB40_RS04980	COG1773	rubredoxin
FOB40_RS04985	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOB40_RS04990	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FOB40_RS04995	COG5557	Pfam Polysulphide reductase, NrfD
FOB40_RS05000	COG0437	4 iron, 4 sulfur cluster binding
FOB40_RS05005	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FOB40_RS05010	COG2203	Gaf domain
FOB40_RS05010	COG3706	GGDEF domain
FOB40_RS05010	COG4251	negative regulation of phosphorylation
FOB40_RS05010	COG5001	Diguanylate cyclase
FOB40_RS05015	COG0438	transferase activity, transferring glycosyl groups
FOB40_RS05020	COG0438	transferase activity, transferring glycosyl groups
FOB40_RS05040	COG0438	transferase activity, transferring glycosyl groups
FOB40_RS05090	COG0438	transferase activity, transferring glycosyl groups
FOB40_RS05095	COG1215	transferase activity, transferring glycosyl groups
FOB40_RS05100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB40_RS05140	COG0784	Response regulator, receiver
FOB40_RS05140	COG2205	protein histidine kinase activity
FOB40_RS05175	COG0730	response to heat
FOB40_RS05185	COG1028	Short-chain dehydrogenase reductase Sdr
FOB40_RS05195	COG1024	Enoyl-CoA hydratase
FOB40_RS05200	COG1024	Enoyl-CoA hydratase
FOB40_RS05205	COG1960	acyl-CoA dehydrogenase activity
FOB40_RS05210	COG1960	acyl-CoA dehydrogenase activity
FOB40_RS05215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOB40_RS05220	COG1024	Enoyl-CoA hydratase
FOB40_RS05250	COG1584	GPR1 FUN34 yaaH family protein
FOB40_RS05265	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB40_RS05270	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB40_RS05275	COG0567	Dehydrogenase, E1 component
FOB40_RS05285	COG1053	succinate dehydrogenase
FOB40_RS05290	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOB40_RS05295	COG2009	succinate dehydrogenase
FOB40_RS05335	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FOB40_RS05350	COG2501	S4 domain
FOB40_RS05360	COG1132	(ABC) transporter
FOB40_RS05365	COG1132	(ABC) transporter
FOB40_RS05375	COG3118	belongs to the thioredoxin family
FOB40_RS05380	COG0471	metal ion transport
FOB40_RS05385	COG0058	SHG alpha-glucan phosphorylase activity
FOB40_RS05400	COG2983	Belongs to the UPF0260 family
FOB40_RS05410	COG1882	Formate acetyltransferase
FOB40_RS05415	COG2116	formate transmembrane transporter activity
FOB40_RS05420	COG1944	ATP diphosphatase activity
FOB40_RS05425	COG2723	6-phospho-beta-galactosidase activity
FOB40_RS05430	COG0583	DNA-binding transcription factor activity
FOB40_RS05440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB40_RS05455	COG1335	isochorismatase
FOB40_RS05465	COG2271	Major facilitator Superfamily
FOB40_RS05470	COG0583	DNA-binding transcription factor activity
FOB40_RS05475	COG0583	DNA-binding transcription factor activity
FOB40_RS05480	COG2910	NAD(P)H-binding
FOB40_RS05510	COG0861	Integral membrane protein TerC family
FOB40_RS05515	COG2885	chlorophyll binding
FOB40_RS05520	COG2199	diguanylate cyclase activity
FOB40_RS05535	COG2154	pterin-4-alpha-carbinolamine dehydratase
FOB40_RS05545	COG1012	belongs to the aldehyde dehydrogenase family
FOB40_RS05550	COG1177	transmembrane transport
FOB40_RS05555	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB40_RS05560	COG3842	ATPase activity
FOB40_RS05565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOB40_RS05570	COG0583	DNA-binding transcription factor activity
FOB40_RS05575	COG3768	UPF0283 membrane protein
FOB40_RS05580	COG3106	COG3106 Predicted ATPase
FOB40_RS05595	COG1842	Phage shock protein A
FOB40_RS05600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOB40_RS05605	COG0747	negative chemotaxis
FOB40_RS05610	COG4168	peptide transport system, permease
FOB40_RS05620	COG4172	Belongs to the ABC transporter superfamily
FOB40_RS05625	COG4172	Belongs to the ABC transporter superfamily
FOB40_RS05630	COG0326	Molecular chaperone. Has ATPase activity
FOB40_RS05635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOB40_RS05655	COG1435	thymidine kinase activity
FOB40_RS05660	COG1757	Na H antiporter
FOB40_RS05665	COG2916	Histone family protein nucleoid-structuring protein H-NS
FOB40_RS05670	COG2096	Adenosyltransferase
FOB40_RS05675	COG3530	Putative quorum-sensing-regulated virulence factor
FOB40_RS05680	COG0602	queuosine metabolic process
FOB40_RS05685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOB40_RS05705	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOB40_RS05715	COG0776	regulation of translation
FOB40_RS05720	COG0539	negative regulation of cytoplasmic translation
FOB40_RS05725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOB40_RS05730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB40_RS05745	COG2814	Major facilitator Superfamily
FOB40_RS05765	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FOB40_RS05770	COG5001	Diguanylate cyclase
FOB40_RS05770	COG3300	MHYT domain
FOB40_RS05775	COG0583	DNA-binding transcription factor activity
FOB40_RS05780	COG3437	response regulator, receiver
FOB40_RS05805	COG4989	oxidoreductase activity
FOB40_RS05810	COG0724	RNA recognition motif
FOB40_RS05820	COG1126	abc transporter atp-binding protein
FOB40_RS05825	COG0765	amino acid transport
FOB40_RS05835	COG4597	amino acid ABC transporter
FOB40_RS05840	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FOB40_RS05850	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FOB40_RS05865	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOB40_RS05870	COG1360	Flagellar Motor Protein
FOB40_RS05875	COG4771	TonB-dependent receptor
FOB40_RS05880	COG1770	oligopeptidase
FOB40_RS05900	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB40_RS05905	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB40_RS05910	COG0649	NAD binding
FOB40_RS05910	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB40_RS05925	COG1034	ATP synthesis coupled electron transport
FOB40_RS05930	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOB40_RS05935	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB40_RS05940	COG0839	Belongs to the complex I subunit 6 family
FOB40_RS05945	COG0713	ATP synthesis coupled electron transport
FOB40_RS05955	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB40_RS05960	COG1007	ATP synthesis coupled electron transport
FOB40_RS05975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOB40_RS05975	COG2199	diguanylate cyclase activity
FOB40_RS05980	COG0047	phosphoribosylformylglycinamidine synthase activity
FOB40_RS05980	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOB40_RS05985	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOB40_RS05995	COG1645	bacterial-type flagellum-dependent swarming motility
FOB40_RS06000	COG1160	GTP binding
FOB40_RS06005	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB40_RS06010	COG2976	Protein conserved in bacteria
FOB40_RS06015	COG0124	histidyl-tRNA synthetase
FOB40_RS06025	COG1426	Protein conserved in bacteria
FOB40_RS06035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOB40_RS06040	COG0105	UTP biosynthetic process
FOB40_RS06055	COG0633	Ferredoxin
FOB40_RS06060	COG0443	Heat shock 70 kDa protein
FOB40_RS06065	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOB40_RS06075	COG0822	iron-sulfur transferase activity
FOB40_RS06080	COG1104	cysteine desulfurase activity
FOB40_RS06100	COG3154	lipid carrier protein
FOB40_RS06105	COG0826	peptidase U32
FOB40_RS06110	COG0826	peptidase U32
FOB40_RS06125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB40_RS06130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB40_RS06135	COG1862	Preprotein translocase
FOB40_RS06140	COG0343	queuine tRNA-ribosyltransferase activity
FOB40_RS06145	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOB40_RS06150	COG0517	IMP dehydrogenase activity
FOB40_RS06160	COG3634	alkyl hydroperoxide reductase activity
FOB40_RS06225	COG1242	4 iron, 4 sulfur cluster binding
FOB40_RS06235	COG0067	glutamate synthase
FOB40_RS06235	COG0069	glutamate synthase activity
FOB40_RS06235	COG0070	glutamate synthase
FOB40_RS06240	COG0493	'glutamate synthase
FOB40_RS06250	COG0513	Belongs to the DEAD box helicase family
FOB40_RS06275	COG0023	Translation Initiation Factor
FOB40_RS06280	COG2119	membrane
FOB40_RS06325	COG0215	cysteine-tRNA ligase activity
FOB40_RS06330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB40_RS06340	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB40_RS06355	COG2261	transglycosylase associated protein
FOB40_RS06360	COG0642	Histidine kinase
FOB40_RS06385	COG0625	glutathione transferase activity
FOB40_RS06395	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FOB40_RS06410	COG0564	pseudouridine synthase activity
FOB40_RS06415	COG4160	amino acid transport
FOB40_RS06425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB40_RS06435	COG2431	L-lysine efflux transmembrane transporter activity
FOB40_RS06440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOB40_RS06445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB40_RS06455	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FOB40_RS06465	COG1393	Belongs to the ArsC family
FOB40_RS06475	COG4783	chaperone-mediated protein folding
FOB40_RS06505	COG3842	ATPase activity
FOB40_RS06510	COG3833	ABC-type maltose transport systems, permease component
FOB40_RS06515	COG1175	transmembrane transport
FOB40_RS06525	COG3081	Nucleoid-associated protein
FOB40_RS06530	COG3082	Protein of unknown function (DUF1414)
FOB40_RS06535	COG3083	sulfuric ester hydrolase activity
FOB40_RS06540	COG1464	Belongs to the NlpA lipoprotein family
FOB40_RS06555	COG0574	Belongs to the PEP-utilizing enzyme family
FOB40_RS06555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB40_RS06560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOB40_RS06585	COG0840	transmembrane signaling receptor activity
FOB40_RS06590	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB40_RS06590	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB40_RS06595	COG0509	glycine decarboxylation via glycine cleavage system
FOB40_RS06600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOB40_RS06605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB40_RS06610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB40_RS06630	COG2814	Major facilitator Superfamily
FOB40_RS06635	COG0625	glutathione transferase activity
FOB40_RS06645	COG0483	inositol monophosphate 1-phosphatase activity
FOB40_RS06655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB40_RS06670	COG1086	Polysaccharide biosynthesis protein
FOB40_RS06675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOB40_RS06685	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOB40_RS06690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOB40_RS06705	COG2089	acid synthase
FOB40_RS06765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB40_RS06765	COG0301	tRNA thio-modification
FOB40_RS06780	COG4953	penicillin-binding protein 1C
FOB40_RS06785	COG2373	Large extracellular alpha-helical protein
FOB40_RS06795	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB40_RS06800	COG5001	Diguanylate cyclase
FOB40_RS06800	COG3300	MHYT domain
FOB40_RS06805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB40_RS06815	COG1252	NADH dehydrogenase
FOB40_RS06820	COG3150	esterase
FOB40_RS06825	COG2233	PERMEase
FOB40_RS06835	COG2354	Protein conserved in bacteria
FOB40_RS06850	COG1301	dicarboxylic acid transport
FOB40_RS06865	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOB40_RS06880	COG0537	adenosine 5'-monophosphoramidase activity
FOB40_RS06915	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB40_RS06920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB40_RS06930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB40_RS06935	COG1605	Chorismate mutase
FOB40_RS06935	COG0287	Prephenate dehydrogenase
FOB40_RS06945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOB40_RS06950	COG0505	Belongs to the CarA family
FOB40_RS06955	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOB40_RS06970	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB40_RS06975	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOB40_RS06980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB40_RS06985	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOB40_RS06990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB40_RS06995	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FOB40_RS07025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB40_RS07030	COG0861	Integral membrane protein TerC family
FOB40_RS07045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB40_RS07050	COG0601	transmembrane transport
FOB40_RS07060	COG2095	MarC family integral membrane protein
FOB40_RS07065	COG1454	alcohol dehydrogenase
FOB40_RS07065	COG1012	belongs to the aldehyde dehydrogenase family
FOB40_RS07070	COG0217	transcriptional regulatory protein
FOB40_RS07075	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOB40_RS07085	COG1801	Protein of unknown function DUF72
FOB40_RS07090	COG4106	trans-aconitate 2-methyltransferase activity
FOB40_RS07095	COG0500	methyltransferase
FOB40_RS07115	COG0450	alkyl hydroperoxide reductase
FOB40_RS07120	COG0583	DNA-binding transcription factor activity
FOB40_RS07125	COG0791	NLP P60 protein
FOB40_RS07135	COG0583	DNA-binding transcription factor activity
FOB40_RS07140	COG2610	gluconate transmembrane transporter activity
FOB40_RS07145	COG3048	D-serine ammonia-lyase activity
FOB40_RS07155	COG0538	isocitrate dehydrogenase activity
FOB40_RS07160	COG2207	Transcriptional regulator
FOB40_RS07170	COG0840	transmembrane signaling receptor activity
FOB40_RS07175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB40_RS07190	COG3152	Membrane
FOB40_RS07225	COG1309	transcriptional regulator
FOB40_RS07260	COG0534	Mate efflux family protein
FOB40_RS07270	COG2841	Protein conserved in bacteria
FOB40_RS07280	COG5001	Diguanylate cyclase
FOB40_RS07280	COG3300	MHYT domain
FOB40_RS07285	COG3132	Protein of unknown function, DUF480
FOB40_RS07315	COG0708	Exodeoxyribonuclease III
FOB40_RS07350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB40_RS07355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB40_RS07365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB40_RS07370	COG1120	ATPase activity
FOB40_RS07375	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB40_RS07380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB40_RS07385	COG2375	cellular response to nickel ion
FOB40_RS07390	COG0784	Response regulator, receiver
FOB40_RS07390	COG3437	response regulator, receiver
FOB40_RS07400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB40_RS07405	COG0328	RNA-DNA hybrid ribonuclease activity
FOB40_RS07410	COG2226	methyltransferase
FOB40_RS07415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB40_RS07420	COG1388	LysM domain
FOB40_RS07420	COG0741	lytic transglycosylase activity
FOB40_RS07445	COG5002	protein histidine kinase activity
FOB40_RS07450	COG0745	RESPONSE REGULATOR receiver
FOB40_RS07455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB40_RS07460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB40_RS07480	COG1609	Transcriptional regulator
FOB40_RS07485	COG2182	Extracellular solute-binding protein
FOB40_RS07490	COG0840	transmembrane signaling receptor activity
FOB40_RS07495	COG1472	Belongs to the glycosyl hydrolase 3 family
FOB40_RS07500	COG2273	Hydrolase Family 16
FOB40_RS07500	COG5297	Belongs to the glycosyl hydrolase family 6
FOB40_RS07505	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB40_RS07515	COG2723	6-phospho-beta-galactosidase activity
FOB40_RS07520	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB40_RS07535	COG1376	ErfK ybiS ycfS ynhG family protein
FOB40_RS07535	COG1388	LysM domain
FOB40_RS07545	COG0471	metal ion transport
FOB40_RS07555	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FOB40_RS07560	COG0791	NLP P60 protein
FOB40_RS07580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB40_RS07585	COG0788	formyltetrahydrofolate deformylase activity
FOB40_RS07595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB40_RS07610	COG1196	nuclear chromosome segregation
FOB40_RS07610	COG0741	lytic transglycosylase activity
FOB40_RS07610	COG0739	heme binding
FOB40_RS07615	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB40_RS07625	COG0436	Aminotransferase
FOB40_RS07630	COG1288	antiporter activity
FOB40_RS07635	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOB40_RS07650	COG2964	Protein conserved in bacteria
FOB40_RS07655	COG3681	Belongs to the UPF0597 family
FOB40_RS07665	COG0814	amino acid
FOB40_RS07685	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FOB40_RS07695	COG1166	arginine decarboxylase activity
FOB40_RS07705	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB40_RS07720	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FOB40_RS07730	COG2353	YceI-like domain
FOB40_RS07735	COG0583	DNA-binding transcription factor activity
FOB40_RS07745	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOB40_RS07750	COG0840	transmembrane signaling receptor activity
FOB40_RS07755	COG0302	gtp cyclohydrolase
FOB40_RS07765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB40_RS07770	COG2267	carboxylic ester hydrolase activity
FOB40_RS07775	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FOB40_RS07790	COG0314	molybdopterin synthase activity
FOB40_RS07795	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOB40_RS07800	COG0315	cyclic pyranopterin monophosphate synthase activity
FOB40_RS07805	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB40_RS07810	COG3005	denitrification pathway
FOB40_RS07820	COG0348	domain, Protein
FOB40_RS07825	COG0437	4 iron, 4 sulfur cluster binding
FOB40_RS07830	COG0243	molybdopterin cofactor binding
FOB40_RS07840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB40_RS07845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOB40_RS07850	COG3850	Histidine kinase
FOB40_RS07855	COG2197	response regulator
FOB40_RS07885	COG0121	glutamine amidotransferase
FOB40_RS07890	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOB40_RS07895	COG1960	acyl-CoA dehydrogenase activity
FOB40_RS07900	COG1473	amidohydrolase
FOB40_RS07905	COG2914	Belongs to the UPF0125 (RnfH) family
FOB40_RS07910	COG2867	negative regulation of translational initiation
FOB40_RS07915	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOB40_RS07925	COG0784	Response regulator, receiver
FOB40_RS07925	COG2205	protein histidine kinase activity
FOB40_RS07935	COG3383	formate dehydrogenase (NAD+) activity
FOB40_RS07965	COG0210	DNA helicase
FOB40_RS07990	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB40_RS07995	COG0426	domain, Protein
FOB40_RS07995	COG1773	rubredoxin
FOB40_RS08000	COG3604	Transcriptional regulator
FOB40_RS08005	COG2197	response regulator
FOB40_RS08010	COG3706	GGDEF domain
FOB40_RS08020	COG2203	Gaf domain
FOB40_RS08020	COG2199	diguanylate cyclase activity
FOB40_RS08025	COG2203	Gaf domain
FOB40_RS08025	COG2199	diguanylate cyclase activity
FOB40_RS08030	COG5642	Protein of unknown function (DUF2384)
FOB40_RS08040	COG2916	Histone family protein nucleoid-structuring protein H-NS
FOB40_RS08115	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOB40_RS08125	COG1960	acyl-CoA dehydrogenase activity
FOB40_RS08130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB40_RS08140	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOB40_RS08145	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOB40_RS08150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB40_RS08150	COG1263	PTS System
FOB40_RS08155	COG1609	Transcriptional regulator
FOB40_RS08165	COG0789	Transcriptional regulator
FOB40_RS08175	COG4821	SIS domain
FOB40_RS08195	COG0783	Belongs to the Dps family
FOB40_RS08220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB40_RS08220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB40_RS08220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB40_RS08225	COG2271	Major facilitator Superfamily
FOB40_RS08230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB40_RS08240	COG1187	pseudouridine synthase activity
FOB40_RS08250	COG0482	sulfurtransferase activity
FOB40_RS08255	COG2915	High frequency lysogenization protein hflD homolog
FOB40_RS08260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOB40_RS08265	COG2850	peptidyl-arginine hydroxylation
FOB40_RS08285	COG0625	glutathione transferase activity
FOB40_RS08290	COG0259	pyridoxamine-phosphate oxidase activity
FOB40_RS08320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB40_RS08320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB40_RS08330	COG1882	Formate acetyltransferase
FOB40_RS08335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB40_RS08345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOB40_RS08350	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOB40_RS08360	COG2853	Lipoprotein
FOB40_RS08370	COG4235	cytochrome complex assembly
FOB40_RS08370	COG3088	subunit of a heme lyase
FOB40_RS08375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB40_RS08380	COG1138	Cytochrome C-type biogenesis protein
FOB40_RS08385	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FOB40_RS08390	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB40_RS08395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB40_RS08400	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB40_RS08415	COG0835	chemotaxis
FOB40_RS08425	COG1192	Involved in chromosome partitioning
FOB40_RS08430	COG1360	Flagellar Motor Protein
FOB40_RS08435	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOB40_RS08440	COG2201	protein-glutamate methylesterase activity
FOB40_RS08445	COG0784	Response regulator, receiver
FOB40_RS08445	COG0643	Histidine kinase
FOB40_RS08445	COG2198	Histidine kinase
FOB40_RS08450	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FOB40_RS08475	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOB40_RS08485	COG1684	flagellar biosynthetic protein fliR
FOB40_RS08490	COG1987	bacterial-type flagellum assembly
FOB40_RS08540	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOB40_RS08550	COG1677	Flagellar hook-basal body complex protein FliE
FOB40_RS08570	COG0469	pyruvate kinase activity
FOB40_RS08575	COG1737	Transcriptional regulator
FOB40_RS08580	COG0837	glucose binding
FOB40_RS08610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB40_RS08630	COG0281	malic enzyme
FOB40_RS08650	COG0437	4 iron, 4 sulfur cluster binding
FOB40_RS08655	COG3383	formate dehydrogenase (NAD+) activity
FOB40_RS08655	COG3383	formate dehydrogenase (NAD+) activity
FOB40_RS08690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOB40_RS08700	COG3852	Histidine kinase
FOB40_RS08715	COG4662	Binding-protein-dependent transport system inner membrane component
FOB40_RS08725	COG0746	molybdenum cofactor guanylyltransferase activity
FOB40_RS08730	COG0303	'Molybdopterin
FOB40_RS08735	COG1289	transmembrane transporter activity
FOB40_RS08740	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOB40_RS08770	COG3220	belongs to the UPF0276 family
FOB40_RS08800	COG0784	Response regulator, receiver
FOB40_RS08800	COG2205	protein histidine kinase activity
FOB40_RS08815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB40_RS08820	COG0444	Belongs to the ABC transporter superfamily
FOB40_RS08825	COG4608	Belongs to the ABC transporter superfamily
FOB40_RS08835	COG2971	BadF BadG BcrA BcrD
FOB40_RS08845	COG0840	transmembrane signaling receptor activity
FOB40_RS08860	COG3724	N-succinylarginine dihydrolase activity
FOB40_RS08885	COG2197	response regulator
FOB40_RS08910	COG2200	EAL domain
FOB40_RS08910	COG2199	diguanylate cyclase activity
FOB40_RS08910	COG2203	Gaf domain
FOB40_RS08915	COG0826	peptidase U32
FOB40_RS08920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB40_RS08930	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOB40_RS08935	COG3706	GGDEF domain
FOB40_RS08940	COG2211	Major facilitator Superfamily
FOB40_RS08945	COG0616	signal peptide processing
FOB40_RS08950	COG1028	Short-chain dehydrogenase reductase Sdr
FOB40_RS08955	COG0583	DNA-binding transcription factor activity
FOB40_RS08965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOB40_RS08980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB40_RS08985	COG1881	PFAM PEBP family protein
FOB40_RS08995	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FOB40_RS08995	COG3408	Glycogen debranching enzyme
FOB40_RS09005	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOB40_RS09020	COG1301	dicarboxylic acid transport
FOB40_RS09025	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FOB40_RS09030	COG2912	Transglutaminase-like superfamily
FOB40_RS09040	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB40_RS09045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOB40_RS09050	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOB40_RS09055	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FOB40_RS09060	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOB40_RS09070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOB40_RS09075	COG0737	Belongs to the 5'-nucleotidase family
FOB40_RS09080	COG0193	aminoacyl-tRNA hydrolase activity
FOB40_RS09085	COG0012	GTP binding
FOB40_RS09130	COG0490	domain, Protein
FOB40_RS09130	COG0471	metal ion transport
FOB40_RS09140	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FOB40_RS09150	COG3097	Belongs to the UPF0267 family
FOB40_RS09155	COG0657	acetylesterase activity
FOB40_RS09165	COG0366	Alpha amylase catalytic
FOB40_RS09170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB40_RS09170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOB40_RS09170	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOB40_RS09170	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOB40_RS09180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB40_RS09195	COG1012	belongs to the aldehyde dehydrogenase family
FOB40_RS09205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOB40_RS09210	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB40_RS09220	COG0180	Tryptophanyl-tRNA synthetase
FOB40_RS09230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOB40_RS09235	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOB40_RS09245	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOB40_RS09250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOB40_RS09280	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOB40_RS09285	COG0583	DNA-binding transcription factor activity
FOB40_RS09305	COG0583	DNA-binding transcription factor activity
FOB40_RS09315	COG0739	heme binding
FOB40_RS09325	COG1511	domain protein
FOB40_RS09325	COG3264	Mechanosensitive ion channel
FOB40_RS09330	COG0584	glycerophosphoryl diester phosphodiesterase
FOB40_RS09340	COG1053	succinate dehydrogenase
FOB40_RS09345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOB40_RS09350	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOB40_RS09355	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOB40_RS09360	COG3366	ferrous iron transmembrane transporter activity
FOB40_RS09365	COG0700	Nucleoside recognition
FOB40_RS09370	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB40_RS09380	COG3214	Protein conserved in bacteria
FOB40_RS09420	COG4221	oxidoreductase activity
FOB40_RS09435	COG0642	Histidine kinase
FOB40_RS09445	COG0516	GMP reductase activity
FOB40_RS09455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB40_RS09465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB40_RS09475	COG5002	protein histidine kinase activity
FOB40_RS09475	COG3447	MASE1 domain protein
FOB40_RS09475	COG5001	Diguanylate cyclase
FOB40_RS09495	COG0583	DNA-binding transcription factor activity
FOB40_RS09500	COG3706	GGDEF domain
FOB40_RS09510	COG1335	isochorismatase
FOB40_RS09515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB40_RS09520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOB40_RS09525	COG1702	phosphate starvation-inducible protein PhoH
FOB40_RS09530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOB40_RS09535	COG4535	Mg2 and Co2 transporter CorC
FOB40_RS09540	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOB40_RS09545	COG0789	Transcriptional regulator
FOB40_RS09560	COG1970	mechanosensitive ion channel activity
FOB40_RS09565	COG4974	Belongs to the 'phage' integrase family
FOB40_RS09570	COG0716	FMN binding
FOB40_RS09580	COG0312	modulator of DNA gyrase
FOB40_RS09585	COG2888	peptidyl-tyrosine sulfation
FOB40_RS09590	COG0495	leucyl-tRNA aminoacylation
FOB40_RS09605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOB40_RS09610	COG0799	negative regulation of ribosome biogenesis
FOB40_RS09615	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOB40_RS09620	COG0768	penicillin binding
FOB40_RS09625	COG0772	Belongs to the SEDS family
FOB40_RS09630	COG2951	lytic endotransglycosylase activity
FOB40_RS09635	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOB40_RS09640	COG1686	Belongs to the peptidase S11 family
FOB40_RS09645	COG2921	Belongs to the UPF0250 family
FOB40_RS09650	COG0321	lipoyl(octanoyl) transferase activity
FOB40_RS09655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOB40_RS09675	COG3139	Protein of unknown function (DUF1315)
FOB40_RS09680	COG0252	asparaginase activity
FOB40_RS09685	COG0786	glutamate:sodium symporter activity
FOB40_RS09700	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOB40_RS09710	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB40_RS09725	COG3610	response to peptide
FOB40_RS09730	COG2966	Psort location CytoplasmicMembrane, score
FOB40_RS09740	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB40_RS09755	COG2897	thiosulfate sulfurtransferase activity
FOB40_RS09760	COG2066	Belongs to the glutaminase family
FOB40_RS09765	COG3171	Protein conserved in bacteria
FOB40_RS09770	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOB40_RS09775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB40_RS09780	COG2200	EAL domain
FOB40_RS09785	COG1090	epimerase
FOB40_RS09790	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOB40_RS09795	COG4181	ATPase activity
FOB40_RS09800	COG2755	lipolytic protein G-D-S-L family
FOB40_RS09805	COG0784	Response regulator, receiver
FOB40_RS09805	COG0835	chemotaxis
FOB40_RS09850	COG3397	chitin binding
FOB40_RS09865	COG3706	GGDEF domain
FOB40_RS09875	COG5002	protein histidine kinase activity
FOB40_RS09875	COG2205	protein histidine kinase activity
FOB40_RS09875	COG0784	Response regulator, receiver
FOB40_RS09885	COG3655	Transcriptional regulator
FOB40_RS09895	COG2814	Major facilitator Superfamily
FOB40_RS09925	COG0748	coenzyme F420 binding
FOB40_RS09930	COG3721	Heme iron utilization protein
FOB40_RS09940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB40_RS09955	COG3340	Belongs to the peptidase S51 family
FOB40_RS09965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB40_RS09980	COG1047	Peptidyl-prolyl cis-trans
FOB40_RS09985	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FOB40_RS09995	COG0835	chemotaxis
FOB40_RS09995	COG0784	Response regulator, receiver
FOB40_RS10000	COG0429	hydrolase of the alpha beta-hydrolase fold
FOB40_RS10005	COG3706	GGDEF domain
FOB40_RS10005	COG4251	negative regulation of phosphorylation
FOB40_RS10005	COG5001	Diguanylate cyclase
FOB40_RS10005	COG2203	Gaf domain
FOB40_RS10010	COG3089	Belongs to the UPF0270 family
FOB40_RS10015	COG3954	Phosphoribulokinase
FOB40_RS10030	COG1765	OsmC-like protein
FOB40_RS10070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB40_RS10075	COG2313	pseudouridylate synthase activity
FOB40_RS10100	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FOB40_RS10125	COG2985	domain, Protein
FOB40_RS10125	COG0569	domain protein
FOB40_RS10130	COG1272	protein, Hemolysin III
FOB40_RS10135	COG0076	glutamate decarboxylase activity
FOB40_RS10140	COG2917	probably involved in intracellular septation
FOB40_RS10145	COG2350	Protein conserved in bacteria
FOB40_RS10155	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOB40_RS10160	COG1381	Involved in DNA repair and RecF pathway recombination
FOB40_RS10175	COG0681	Belongs to the peptidase S26 family
FOB40_RS10180	COG0481	GTPase activity
FOB40_RS10190	COG3026	antisigma factor binding
FOB40_RS10195	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FOB40_RS10200	COG1595	DNA-templated transcription, initiation
FOB40_RS10205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOB40_RS10215	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FOB40_RS10220	COG0354	folic acid binding
FOB40_RS10245	COG4232	protein-disulfide reductase activity
FOB40_RS10260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB40_RS10265	COG0191	fructose-bisphosphate aldolase activity
FOB40_RS10270	COG0126	phosphoglycerate kinase activity
FOB40_RS10275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB40_RS10280	COG1940	carbohydrate kinase activity
FOB40_RS10285	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOB40_RS10290	COG2816	NAD+ diphosphatase activity
FOB40_RS10300	COG4991	sh3 domain protein
FOB40_RS10305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB40_RS10315	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOB40_RS10345	COG4191	Histidine kinase
FOB40_RS10355	COG2816	NAD+ diphosphatase activity
FOB40_RS10400	COG1858	cytochrome C peroxidase
FOB40_RS10405	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
FOB40_RS10415	COG2203	Gaf domain
FOB40_RS10415	COG2199	diguanylate cyclase activity
FOB40_RS10420	COG0513	Belongs to the DEAD box helicase family
FOB40_RS10455	COG0154	amidase activity
FOB40_RS10460	COG2957	Belongs to the agmatine deiminase family
FOB40_RS10475	COG1902	pentaerythritol trinitrate reductase activity
FOB40_RS10490	COG1238	metal cluster binding
FOB40_RS10495	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOB40_RS10500	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOB40_RS10505	COG0585	pseudouridine synthase activity
FOB40_RS10515	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOB40_RS10520	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOB40_RS10525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB40_RS10535	COG1376	ErfK ybiS ycfS ynhG family protein
FOB40_RS10540	COG0668	transmembrane transport
FOB40_RS10550	COG2731	YhcH YjgK YiaL family protein
FOB40_RS10560	COG1794	racemase activity, acting on amino acids and derivatives
FOB40_RS10575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB40_RS10595	COG0488	(ABC) transporter
FOB40_RS10605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOB40_RS10645	COG0148	phosphopyruvate hydratase activity
FOB40_RS10650	COG0504	CTP synthase activity
FOB40_RS10655	COG3956	TIGRFAM MazG family protein
FOB40_RS10660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB40_RS10665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB40_RS10675	COG4807	Protein conserved in bacteria
FOB40_RS10680	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB40_RS10685	COG0783	Belongs to the Dps family
FOB40_RS10690	COG1151	hydroxylamine reductase activity
FOB40_RS10695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB40_RS10700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB40_RS10705	COG0671	phosphoesterase, PA-phosphatase related
FOB40_RS10710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB40_RS10715	COG0163	prenyltransferase activity
FOB40_RS10730	COG1131	(ABC) transporter
FOB40_RS10735	COG0842	Transport permease protein
FOB40_RS10740	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FOB40_RS10745	COG1924	4 iron, 4 sulfur cluster binding
FOB40_RS10765	COG1823	symporter activity
FOB40_RS10775	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOB40_RS10780	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOB40_RS10785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOB40_RS10795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB40_RS10800	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOB40_RS10805	COG1489	DNA binding
FOB40_RS10815	COG1643	Atp-dependent helicase
FOB40_RS10820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB40_RS10825	COG0346	lactoylglutathione lyase activity
FOB40_RS10830	COG2076	Multidrug Resistance protein
FOB40_RS10835	COG2076	Multidrug Resistance protein
FOB40_RS10845	COG3437	response regulator, receiver
FOB40_RS10845	COG0784	Response regulator, receiver
FOB40_RS10850	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOB40_RS10865	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOB40_RS10880	COG1136	(ABC) transporter
FOB40_RS10900	COG0840	transmembrane signaling receptor activity
FOB40_RS10915	COG0529	Catalyzes the synthesis of activated sulfate
FOB40_RS10920	COG0471	metal ion transport
FOB40_RS10920	COG3273	potassium ion transport
FOB40_RS10925	COG2895	sulfate adenylyltransferase (ATP) activity
FOB40_RS10930	COG0175	sulfate reduction
FOB40_RS10935	COG1648	precorrin-2 dehydrogenase activity
FOB40_RS10935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB40_RS10940	COG0330	HflC and HflK could
FOB40_RS10945	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOB40_RS10950	COG0840	transmembrane signaling receptor activity
FOB40_RS10955	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOB40_RS10965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB40_RS10970	COG1640	4-alpha-glucanotransferase
FOB40_RS10975	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOB40_RS11025	COG0561	phosphatase activity
FOB40_RS11040	COG0733	neurotransmitter:sodium symporter activity
FOB40_RS11050	COG0733	neurotransmitter:sodium symporter activity
FOB40_RS11115	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FOB40_RS11120	COG2885	chlorophyll binding
FOB40_RS11125	COG0823	Involved in the tonB-independent uptake of proteins
FOB40_RS11140	COG0811	peptide transport
FOB40_RS11145	COG0824	Thioesterase
FOB40_RS11150	COG3790	cyd operon protein YbgE
FOB40_RS11155	COG4890	Cyd operon protein YbgT
FOB40_RS11160	COG1294	oxidase, subunit
FOB40_RS11170	COG2255	four-way junction helicase activity
FOB40_RS11175	COG0632	four-way junction helicase activity
FOB40_RS11180	COG0840	transmembrane signaling receptor activity
FOB40_RS11190	COG2771	luxR family
FOB40_RS11195	COG3916	Acyl-homoserine-lactone synthase
FOB40_RS11205	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FOB40_RS11210	COG5001	Diguanylate cyclase
FOB40_RS11210	COG4251	negative regulation of phosphorylation
FOB40_RS11210	COG3706	GGDEF domain
FOB40_RS11210	COG2203	Gaf domain
FOB40_RS11220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB40_RS11230	COG2995	paraquat-inducible protein a
FOB40_RS11235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB40_RS11235	COG3008	intermembrane lipid transfer
FOB40_RS11245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB40_RS11250	COG0442	prolyl-tRNA aminoacylation
FOB40_RS11255	COG4221	oxidoreductase activity
FOB40_RS11270	COG1024	Enoyl-CoA hydratase
FOB40_RS11280	COG0110	maltose O-acetyltransferase activity
FOB40_RS11290	COG4166	transmembrane transport
FOB40_RS11300	COG0840	transmembrane signaling receptor activity
FOB40_RS11305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB40_RS11345	COG3778	Protein conserved in bacteria
FOB40_RS11350	COG3299	homolog of phage Mu protein gp47
FOB40_RS11390	COG4386	tail sheath protein
FOB40_RS11430	COG0616	signal peptide processing
FOB40_RS11445	COG1802	Transcriptional regulator
FOB40_RS11445	COG4626	Terminase
FOB40_RS11475	COG2771	luxR family
FOB40_RS11515	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOB40_RS11595	COG1846	Transcriptional regulator
FOB40_RS11605	COG3646	Phage regulatory protein
FOB40_RS11690	COG0735	belongs to the Fur family
FOB40_RS11715	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOB40_RS11720	COG0513	Belongs to the DEAD box helicase family
FOB40_RS11725	COG2153	protein acetylation
FOB40_RS11735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB40_RS11740	COG0557	exoribonuclease II activity
FOB40_RS11745	COG3706	GGDEF domain
FOB40_RS11750	COG2885	chlorophyll binding
FOB40_RS11750	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOB40_RS11755	COG3240	lipase activity
FOB40_RS11760	COG3111	PFAM Bacterial OB fold (BOF) protein
FOB40_RS11770	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FOB40_RS11775	COG1194	a g-specific adenine glycosylase
FOB40_RS11780	COG0617	tRNA 3'-terminal CCA addition
FOB40_RS11800	COG3068	Protein conserved in bacteria
FOB40_RS11810	COG0739	heme binding
FOB40_RS11830	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FOB40_RS11835	COG1121	(ABC) transporter
FOB40_RS11840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB40_RS11845	COG0583	DNA-binding transcription factor activity
FOB40_RS11850	COG0697	spore germination
FOB40_RS11855	COG1573	uracil-dna glycosylase
FOB40_RS11870	COG2827	Endonuclease containing a URI domain
FOB40_RS11885	COG1842	Phage shock protein A
FOB40_RS11890	COG0204	Acyl-transferase
FOB40_RS11910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB40_RS11915	COG0583	DNA-binding transcription factor activity
FOB40_RS11920	COG2084	Dehydrogenase
FOB40_RS11950	COG3104	oligopeptide transport
FOB40_RS11970	COG3150	esterase
FOB40_RS11980	COG3151	Protein conserved in bacteria
FOB40_RS11985	COG0494	nUDIX hydrolase
FOB40_RS11990	COG1538	Outer membrane efflux protein
FOB40_RS11995	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOB40_RS11995	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOB40_RS12000	COG1560	Kdo2-lipid A biosynthetic process
FOB40_RS12005	COG2213	PTS system mannitol-specific
FOB40_RS12005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB40_RS12010	COG0246	Mannitol dehydrogenase
FOB40_RS12015	COG3722	fumarate hydratase activity
FOB40_RS12025	COG0484	heat shock protein binding
FOB40_RS12045	COG1671	Belongs to the UPF0178 family
FOB40_RS12050	COG1988	membrane-bound metal-dependent
FOB40_RS12055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB40_RS12060	COG0513	Belongs to the DEAD box helicase family
FOB40_RS12085	COG1575	Belongs to the MenA family. Type 1 subfamily
FOB40_RS12090	COG1169	isochorismate synthase
FOB40_RS12095	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOB40_RS12100	COG0596	Alpha beta hydrolase
FOB40_RS12105	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOB40_RS12110	COG1441	menaquinone biosynthetic process
FOB40_RS12115	COG0318	PFAM AMP-dependent synthetase and ligase
FOB40_RS12120	COG3291	Pkd domain containing protein
FOB40_RS12125	COG2949	membrane
FOB40_RS12130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOB40_RS12140	COG0784	Response regulator, receiver
FOB40_RS12140	COG0835	chemotaxis
FOB40_RS12150	COG1444	tRNA N-acetyltransferase activity
FOB40_RS12170	COG1803	Methylglyoxal synthase
FOB40_RS12175	COG1979	alcohol dehydrogenase
FOB40_RS12190	COG4221	oxidoreductase activity
FOB40_RS12230	COG1368	sulfuric ester hydrolase activity
FOB40_RS12235	COG1522	sequence-specific DNA binding
FOB40_RS12245	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOB40_RS12255	COG1546	Belongs to the CinA family
FOB40_RS12255	COG1058	Belongs to the CinA family
FOB40_RS12265	COG0561	phosphatase activity
FOB40_RS12275	COG2926	Belongs to the UPF0265 family
FOB40_RS12310	COG1396	sequence-specific DNA binding
FOB40_RS12315	COG3135	benzoate transporter
FOB40_RS12340	COG0840	transmembrane signaling receptor activity
FOB40_RS12345	COG3047	cAMP biosynthetic process
FOB40_RS12355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOB40_RS12390	COG2197	response regulator
FOB40_RS12410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOB40_RS12420	COG1278	Cold shock
FOB40_RS12425	COG2252	PERMEase
FOB40_RS12430	COG2376	Dihydroxyacetone kinase
FOB40_RS12435	COG1461	Dihydroxyacetone kinase
FOB40_RS12450	COG3284	Transcriptional regulator
FOB40_RS12465	COG0628	permease
FOB40_RS12470	COG0671	phosphoesterase, PA-phosphatase related
FOB40_RS12485	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOB40_RS12490	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FOB40_RS12510	COG0456	acetyltransferase
FOB40_RS12515	COG3133	Outer membrane lipoprotein
FOB40_RS12520	COG0004	ammonium transporteR
FOB40_RS12525	COG3706	GGDEF domain
FOB40_RS12535	COG3932	Exopolysaccharide synthesis, ExoD
FOB40_RS12540	COG0814	amino acid
FOB40_RS12545	COG3706	GGDEF domain
FOB40_RS12555	COG0110	maltose O-acetyltransferase activity
FOB40_RS12560	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOB40_RS12570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOB40_RS12575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB40_RS12585	COG0137	argininosuccinate synthase activity
FOB40_RS12590	COG0165	Argininosuccinate lyase
FOB40_RS12610	COG3314	Sporulation integral membrane protein YlbJ
FOB40_RS12635	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOB40_RS12640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOB40_RS12655	COG0477	Major facilitator Superfamily
FOB40_RS12670	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB40_RS12675	COG0523	cobalamin synthesis protein
FOB40_RS12685	COG2200	EAL domain
FOB40_RS12690	COG1049	propionate catabolic process, 2-methylcitrate cycle
FOB40_RS12695	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOB40_RS12700	COG0840	transmembrane signaling receptor activity
FOB40_RS12710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB40_RS12715	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB40_RS12720	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOB40_RS12725	COG2186	Transcriptional regulator
FOB40_RS12755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB40_RS12760	COG1459	type II secretion system
FOB40_RS12775	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FOB40_RS12780	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FOB40_RS12785	COG0494	nUDIX hydrolase
FOB40_RS12790	COG0653	protein targeting
FOB40_RS12800	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FOB40_RS12805	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOB40_RS12810	COG0849	cell division
FOB40_RS12820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB40_RS12825	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOB40_RS12830	COG0772	Belongs to the SEDS family
FOB40_RS12835	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOB40_RS12840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB40_RS12845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB40_RS12855	COG0768	penicillin binding
FOB40_RS12860	COG3116	cell division
FOB40_RS12865	COG0275	rRNA processing
FOB40_RS12870	COG2001	Belongs to the MraZ family
FOB40_RS12880	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOB40_RS12885	COG3107	peptidoglycan biosynthetic process
FOB40_RS12890	COG0792	nuclease activity
FOB40_RS12895	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOB40_RS12905	COG2969	positive regulation of protein catabolic process
FOB40_RS12910	COG0625	glutathione transferase activity
FOB40_RS12915	COG2857	Cytochrome c1
FOB40_RS12920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOB40_RS12925	COG0723	plastoquinol--plastocyanin reductase activity
FOB40_RS12930	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOB40_RS12935	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOB40_RS12940	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOB40_RS12950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB40_RS12955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB40_RS12985	COG3964	amidohydrolase
FOB40_RS13000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB40_RS13000	COG3711	transcriptional antiterminator
FOB40_RS13005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB40_RS13010	COG1660	Displays ATPase and GTPase activities
FOB40_RS13015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB40_RS13030	COG1137	ATPase activity
FOB40_RS13035	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOB40_RS13040	COG3117	lipopolysaccharide transmembrane transporter activity
FOB40_RS13045	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOB40_RS13050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOB40_RS13050	COG0517	IMP dehydrogenase activity
FOB40_RS13055	COG1127	ABC transporter
FOB40_RS13060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOB40_RS13065	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB40_RS13070	COG2854	intermembrane phospholipid transfer
FOB40_RS13080	COG5007	Belongs to the BolA IbaG family
FOB40_RS13085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOB40_RS13090	COG0312	modulator of DNA gyrase
FOB40_RS13095	COG3028	Belongs to the UPF0307 family
FOB40_RS13100	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOB40_RS13120	COG1011	Hydrolase
FOB40_RS13135	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOB40_RS13140	COG0019	diaminopimelate decarboxylase activity
FOB40_RS13150	COG1965	Belongs to the frataxin family
FOB40_RS13155	COG0400	carboxylic ester hydrolase activity
FOB40_RS13160	COG3072	Adenylate cyclase
FOB40_RS13165	COG0181	hydroxymethylbilane synthase activity
FOB40_RS13175	COG2959	enzyme of heme biosynthesis
FOB40_RS13190	COG1494	fructose-1,6-bisphosphatase
FOB40_RS13245	COG0795	lipopolysaccharide-transporting ATPase activity
FOB40_RS13250	COG0795	lipopolysaccharide-transporting ATPase activity
FOB40_RS13255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOB40_RS13260	COG2927	DNA polymerase III (CHI subunit)
FOB40_RS13290	COG0753	catalase activity
FOB40_RS13315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB40_RS13320	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FOB40_RS13325	COG5380	lipid catabolic process
FOB40_RS13345	COG4533	DNA binding
FOB40_RS13355	COG2873	o-acetylhomoserine
FOB40_RS13385	COG3842	ATPase activity
FOB40_RS13395	COG1175	transmembrane transport
FOB40_RS13435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB40_RS13440	COG1074	ATP-dependent DNA helicase activity
FOB40_RS13445	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FOB40_RS13450	COG2259	Doxx family
FOB40_RS13455	COG1741	Belongs to the pirin family
FOB40_RS13465	COG0583	DNA-binding transcription factor activity
FOB40_RS13490	COG3706	GGDEF domain
FOB40_RS13495	COG4771	TonB-dependent receptor
FOB40_RS13535	COG0203	ribosomal protein L17
FOB40_RS13540	COG0202	RNA polymerase activity
FOB40_RS13545	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOB40_RS13550	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOB40_RS13555	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOB40_RS13560	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOB40_RS13565	COG0201	protein transport
FOB40_RS13570	COG0200	Binds to the 23S rRNA
FOB40_RS13575	COG1841	ribosomal large subunit assembly
FOB40_RS13580	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOB40_RS13585	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOB40_RS13590	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOB40_RS13595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOB40_RS13600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOB40_RS13605	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOB40_RS13610	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOB40_RS13615	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOB40_RS13620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOB40_RS13625	COG0255	Belongs to the universal ribosomal protein uL29 family
FOB40_RS13630	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOB40_RS13635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOB40_RS13640	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOB40_RS13645	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOB40_RS13650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOB40_RS13655	COG0089	rRNA binding
FOB40_RS13660	COG0088	Forms part of the polypeptide exit tunnel
FOB40_RS13665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOB40_RS13670	COG0051	transcription antitermination factor activity, RNA binding
FOB40_RS13690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB40_RS13695	COG2183	response to ionizing radiation
FOB40_RS13715	COG0596	Alpha beta hydrolase
FOB40_RS13720	COG1040	competence protein
FOB40_RS13725	COG0316	Belongs to the HesB IscA family
FOB40_RS13725	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOB40_RS13730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOB40_RS13735	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FOB40_RS13740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB40_RS13745	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOB40_RS13750	COG4942	peptidase
FOB40_RS13760	COG1609	Transcriptional regulator
FOB40_RS13775	COG0800	Aldolase
FOB40_RS13785	COG3265	gluconokinase activity
FOB40_RS13790	COG2610	gluconate transmembrane transporter activity
FOB40_RS13795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB40_RS13800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOB40_RS13810	COG0456	acetyltransferase
FOB40_RS13815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOB40_RS13820	COG1490	D-aminoacyl-tRNA deacylase activity
FOB40_RS13825	COG1295	ribonuclease BN
FOB40_RS13830	COG0281	malic enzyme
FOB40_RS13835	COG0814	amino acid
FOB40_RS13840	COG0702	epimerase
FOB40_RS13850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOB40_RS13855	COG0254	rRNA binding
FOB40_RS13870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB40_RS13875	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOB40_RS13885	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOB40_RS13895	COG0514	ATP-dependent DNA helicase (RecQ)
FOB40_RS13900	COG2050	protein possibly involved in aromatic compounds catabolism
FOB40_RS13920	COG2258	MOSC domain
FOB40_RS13925	COG1177	transmembrane transport
FOB40_RS13930	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB40_RS13935	COG3842	ATPase activity
FOB40_RS13955	COG0174	glutamine synthetase
FOB40_RS13975	COG3045	CreA protein
FOB40_RS13980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB40_RS13985	COG0443	Heat shock 70 kDa protein
FOB40_RS14000	COG0366	Alpha amylase catalytic
FOB40_RS14015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB40_RS14025	COG4211	Belongs to the binding-protein-dependent transport system permease family
FOB40_RS14030	COG1129	ABC transporter
FOB40_RS14040	COG3250	beta-galactosidase activity
FOB40_RS14045	COG1609	Transcriptional regulator
FOB40_RS14050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB40_RS14055	COG1085	galactose-1-phosphate uridylyltransferase
FOB40_RS14060	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOB40_RS14065	COG2017	converts alpha-aldose to the beta-anomer
FOB40_RS14070	COG1968	undecaprenyl-diphosphatase activity
FOB40_RS14080	COG1595	DNA-templated transcription, initiation
FOB40_RS14090	COG0018	arginyl-trna synthetase
FOB40_RS14100	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FOB40_RS14105	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOB40_RS14115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB40_RS14120	COG1131	(ABC) transporter
FOB40_RS14125	COG0842	Transport permease protein
FOB40_RS14130	COG0842	Transport permease protein
FOB40_RS14135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB40_RS14145	COG2116	formate transmembrane transporter activity
FOB40_RS14150	COG1648	precorrin-2 dehydrogenase activity
FOB40_RS14150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB40_RS14155	COG2239	Acts as a magnesium transporter
FOB40_RS14165	COG0737	Belongs to the 5'-nucleotidase family
FOB40_RS14175	COG1079	Belongs to the binding-protein-dependent transport system permease family
FOB40_RS14180	COG4603	Belongs to the binding-protein-dependent transport system permease family
FOB40_RS14185	COG3845	ABC transporter
FOB40_RS14190	COG1744	ABC transporter substrate-binding protein PnrA-like
FOB40_RS14195	COG0210	DNA helicase
FOB40_RS14210	COG1943	Transposase
FOB40_RS14240	COG1280	lysine exporter protein (LysE YggA)
FOB40_RS14265	COG1215	transferase activity, transferring glycosyl groups
FOB40_RS14270	COG3307	-O-antigen
FOB40_RS14280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB40_RS14295	COG1063	alcohol dehydrogenase
FOB40_RS14300	COG3245	cytochrome
FOB40_RS14315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOB40_RS14320	COG2166	iron-sulfur cluster assembly
FOB40_RS14325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOB40_RS14360	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOB40_RS14370	COG0583	DNA-binding transcription factor activity
FOB40_RS14385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOB40_RS14390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOB40_RS14395	COG2223	nitrite transmembrane transporter activity
FOB40_RS14400	COG3279	Response regulator of the LytR AlgR family
FOB40_RS14405	COG3275	phosphorelay sensor kinase activity
FOB40_RS14410	COG2081	HI0933 family
FOB40_RS14415	COG1528	Iron-storage protein
FOB40_RS14420	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOB40_RS14425	COG0589	response to stress
FOB40_RS14465	COG3642	lipopolysaccharide core region biosynthetic process
FOB40_RS14470	COG0859	PFAM glycosyl transferase family 9
FOB40_RS14480	COG0194	GDP metabolic process
FOB40_RS14485	COG1758	RNA polymerase activity
FOB40_RS14490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB40_RS14495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB40_RS14505	COG2267	carboxylic ester hydrolase activity
FOB40_RS14510	COG0561	phosphatase activity
FOB40_RS14540	COG1309	transcriptional regulator
FOB40_RS14545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB40_RS14550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB40_RS14555	COG4191	Histidine kinase
FOB40_RS14555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB40_RS14560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB40_RS14585	COG2205	protein histidine kinase activity
FOB40_RS14590	COG0745	RESPONSE REGULATOR receiver
FOB40_RS14595	COG2814	Major facilitator Superfamily
FOB40_RS14610	COG3977	Valine--pyruvate aminotransferase
FOB40_RS14615	COG0071	Belongs to the small heat shock protein (HSP20) family
FOB40_RS14620	COG0071	Belongs to the small heat shock protein (HSP20) family
FOB40_RS14625	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOB40_RS14635	COG2378	regulation of single-species biofilm formation
FOB40_RS14645	COG0187	DNA topoisomerase II activity
FOB40_RS14655	COG0592	DNA-directed DNA polymerase activity
FOB40_RS14660	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOB40_RS14675	COG1126	abc transporter atp-binding protein
FOB40_RS14680	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOB40_RS14685	COG0594	ribonuclease P activity
FOB40_RS14690	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOB40_RS14695	COG0706	membrane insertase activity
FOB40_RS14700	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOB40_RS14705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB40_RS14710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB40_RS14715	COG1120	ATPase activity
FOB40_RS14720	COG4615	Cyclic peptide transporter
FOB40_RS14730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOB40_RS14735	COG0445	tRNA wobble uridine modification
FOB40_RS14740	COG0357	Ribosomal RNA small subunit methyltransferase G
FOB40_RS14745	COG1192	Involved in chromosome partitioning
FOB40_RS14750	COG1475	DNA binding
FOB40_RS14760	COG0356	it plays a direct role in the translocation of protons across the membrane
FOB40_RS14770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOB40_RS14775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOB40_RS14780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOB40_RS14785	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOB40_RS14790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOB40_RS14795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOB40_RS14800	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOB40_RS14805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB40_RS14850	COG0297	glycogen (starch) synthase activity
FOB40_RS14850	COG0438	transferase activity, transferring glycosyl groups
FOB40_RS14865	COG4452	Inner membrane protein CreD
FOB40_RS14880	COG2205	protein histidine kinase activity
FOB40_RS14885	COG0745	RESPONSE REGULATOR receiver
FOB40_RS14890	COG1349	DNA-binding transcription factor activity
FOB40_RS14895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOB40_RS14900	COG2771	luxR family
FOB40_RS14910	COG0811	peptide transport
FOB40_RS14915	COG0811	peptide transport
FOB40_RS14920	COG0848	biopolymer transport protein
FOB40_RS14925	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FOB40_RS14970	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOB40_RS14975	COG0402	S-adenosylhomocysteine deaminase activity
FOB40_RS14980	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOB40_RS14985	COG2226	methyltransferase
FOB40_RS14990	COG3165	ubiquinone biosynthetic process from chorismate
FOB40_RS14995	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOB40_RS15000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB40_RS15005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB40_RS15010	COG0805	protein transport
FOB40_RS15025	COG3397	chitin binding
FOB40_RS15030	COG3469	chitinase activity
FOB40_RS15050	COG0742	ribosomal rna small subunit methyltransferase
FOB40_RS15060	COG0248	Ppx GppA phosphatase
FOB40_RS15065	COG0513	Belongs to the DEAD box helicase family
FOB40_RS15070	COG3118	belongs to the thioredoxin family
FOB40_RS15085	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOB40_RS15095	COG5001	Diguanylate cyclase
FOB40_RS15100	COG2960	long-chain fatty acid transporting porin activity
FOB40_RS15115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB40_RS15145	COG1609	Transcriptional regulator
FOB40_RS15160	COG2188	Transcriptional regulator
FOB40_RS15185	COG0751	glycine-tRNA ligase activity
FOB40_RS15190	COG0752	glycyl-tRNA synthetase alpha subunit
FOB40_RS15195	COG2818	Glycosylase
FOB40_RS15200	COG2885	chlorophyll binding
FOB40_RS15205	COG0251	oxidation-reduction process
FOB40_RS15210	COG0425	Belongs to the sulfur carrier protein TusA family
FOB40_RS15235	COG0183	Belongs to the thiolase family
FOB40_RS15240	COG1024	Enoyl-CoA hydratase
FOB40_RS15240	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB40_RS15245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB40_RS15250	COG0006	proline dipeptidase activity
FOB40_RS15255	COG1739	Uncharacterized protein family UPF0029
FOB40_RS15260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB40_RS15265	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FOB40_RS15295	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB40_RS15295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB40_RS15295	COG1042	CoA-binding domain protein
FOB40_RS15315	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOB40_RS15320	COG0166	Belongs to the GPI family
FOB40_RS15325	COG0668	transmembrane transport
FOB40_RS15330	COG1309	transcriptional regulator
FOB40_RS15335	COG0756	dUTP diphosphatase activity
FOB40_RS15340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOB40_RS15345	COG2003	Belongs to the UPF0758 family
FOB40_RS15350	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOB40_RS15355	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOB40_RS15365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOB40_RS15370	COG2990	Protein conserved in bacteria
FOB40_RS15375	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOB40_RS15380	COG0859	PFAM glycosyl transferase family 9
FOB40_RS15385	COG0463	Glycosyl transferase, family 2
FOB40_RS15390	COG0859	PFAM glycosyl transferase family 9
FOB40_RS15395	COG1519	Transferase
FOB40_RS15410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB40_RS15415	COG1609	Transcriptional regulator
FOB40_RS15420	COG0604	alcohol dehydrogenase
FOB40_RS15445	COG3161	chorismate lyase activity
FOB40_RS15450	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FOB40_RS15455	COG2937	Belongs to the GPAT DAPAT family
FOB40_RS15460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOB40_RS15475	COG0534	Mate efflux family protein
FOB40_RS15480	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOB40_RS15485	COG2205	protein histidine kinase activity
FOB40_RS15490	COG0745	RESPONSE REGULATOR receiver
FOB40_RS15500	COG1045	serine acetyltransferase
FOB40_RS15510	COG3074	FtsZ-dependent cytokinesis
FOB40_RS15515	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FOB40_RS15525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB40_RS15525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB40_RS15530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOB40_RS15565	COG1609	Transcriptional regulator
FOB40_RS15570	COG3250	beta-galactosidase activity
FOB40_RS15575	COG2731	YhcH YjgK YiaL family protein
FOB40_RS15580	COG0531	amino acid
FOB40_RS15585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB40_RS15590	COG0531	amino acid
FOB40_RS15595	COG0385	Bile acid
FOB40_RS15600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FOB40_RS15640	COG0583	DNA-binding transcription factor activity
FOB40_RS15655	COG0583	DNA-binding transcription factor activity
FOB40_RS15660	COG1561	YicC-like family, N-terminal region
FOB40_RS15665	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOB40_RS15670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOB40_RS15685	COG3706	GGDEF domain
FOB40_RS15685	COG2203	Gaf domain
FOB40_RS15685	COG5001	Diguanylate cyclase
FOB40_RS15685	COG4251	negative regulation of phosphorylation
FOB40_RS15690	COG3084	Protein conserved in bacteria
FOB40_RS15700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOB40_RS15705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB40_RS15715	COG1335	isochorismatase
FOB40_RS15725	COG1683	Conserved Protein
FOB40_RS15730	COG0204	Acyl-transferase
FOB40_RS15735	COG0204	Acyl-transferase
FOB40_RS15740	COG0606	chelatase, subunit chli
FOB40_RS15755	COG3978	acetolactate synthase activity
FOB40_RS15765	COG0129	dihydroxy-acid dehydratase activity
FOB40_RS15780	COG2391	methyltransferase activity
FOB40_RS15790	COG2962	Rard protein
FOB40_RS15800	COG1012	belongs to the aldehyde dehydrogenase family
FOB40_RS15805	COG1396	sequence-specific DNA binding
FOB40_RS15810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB40_RS15820	COG0519	Catalyzes the synthesis of GMP from XMP
FOB40_RS15820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOB40_RS15825	COG0583	DNA-binding transcription factor activity
FOB40_RS15830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB40_RS15855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB40_RS15860	COG2204	response regulator
FOB40_RS15875	COG0174	glutamine synthetase
FOB40_RS15880	COG1217	gtp-binding protein TYPA
FOB40_RS15885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB40_RS15890	COG0569	domain protein
FOB40_RS15895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB40_RS15895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB40_RS15900	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOB40_RS15905	COG0242	peptide deformylase activity
FOB40_RS15910	COG1652	LysM domain
FOB40_RS15915	COG0758	DNA mediated transformation
FOB40_RS15920	COG2922	Belongs to the Smg family
FOB40_RS15925	COG0551	DNA topoisomerase type I activity
FOB40_RS15935	COG0009	L-threonylcarbamoyladenylate synthase
FOB40_RS15940	COG0408	coproporphyrinogen oxidase activity
FOB40_RS15945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOB40_RS15955	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOB40_RS15970	COG3078	GTPase activator activity
FOB40_RS15980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB40_RS16005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOB40_RS16010	COG1288	antiporter activity
FOB40_RS16015	COG1438	arginine binding
FOB40_RS16020	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FOB40_RS16025	COG0540	Belongs to the ATCase OTCase family
FOB40_RS16040	COG0583	DNA-binding transcription factor activity
FOB40_RS16055	COG3040	lipid binding
FOB40_RS16060	COG2207	Transcriptional regulator
FOB40_RS16065	COG1979	alcohol dehydrogenase
FOB40_RS16070	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOB40_RS16075	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOB40_RS16085	COG2964	Protein conserved in bacteria
FOB40_RS16090	COG3681	Belongs to the UPF0597 family
FOB40_RS16100	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB40_RS16105	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB40_RS16110	COG0564	pseudouridine synthase activity
FOB40_RS16120	COG0542	response to heat
FOB40_RS16125	COG2502	aspartate--ammonia ligase
FOB40_RS16130	COG1522	sequence-specific DNA binding
FOB40_RS16140	COG5413	integral membrane protein
FOB40_RS16145	COG0516	GMP reductase activity
FOB40_RS16145	COG0517	IMP dehydrogenase activity
FOB40_RS16150	COG1028	Short-chain dehydrogenase reductase Sdr
FOB40_RS16165	COG2205	protein histidine kinase activity
FOB40_RS16175	COG2204	response regulator
FOB40_RS16225	COG0243	molybdopterin cofactor binding
FOB40_RS16230	COG3005	denitrification pathway
FOB40_RS16235	COG4191	Histidine kinase
FOB40_RS16235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB40_RS16265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB40_RS16270	COG0569	domain protein
FOB40_RS16275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOB40_RS16300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB40_RS16315	COG0250	Participates in transcription elongation, termination and antitermination
FOB40_RS16320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOB40_RS16325	COG0081	regulation of translation
FOB40_RS16330	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOB40_RS16335	COG0222	ribosome binding
FOB40_RS16340	COG0085	RNA polymerase activity
FOB40_RS16345	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOB40_RS16350	COG2964	Protein conserved in bacteria
FOB40_RS16360	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOB40_RS16370	COG2168	tRNA wobble position uridine thiolation
FOB40_RS16375	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOB40_RS16380	COG0049	tRNA binding
FOB40_RS16385	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOB40_RS16390	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB40_RS16395	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOB40_RS16445	COG3714	YhhN family
FOB40_RS16470	COG1301	dicarboxylic acid transport
FOB40_RS16480	COG2095	MarC family integral membrane protein
FOB40_RS16490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB40_RS16500	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOB40_RS16505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB40_RS16520	COG1770	oligopeptidase
FOB40_RS16535	COG4221	oxidoreductase activity
FOB40_RS16540	COG0583	DNA-binding transcription factor activity
FOB40_RS16545	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB40_RS16570	COG0742	ribosomal rna small subunit methyltransferase
FOB40_RS16575	COG0552	protein localization to endoplasmic reticulum
FOB40_RS16580	COG2884	Cell division ATP-binding protein ftsE
FOB40_RS16585	COG2177	Part of the ABC transporter FtsEX involved in
FOB40_RS16595	COG0288	reversible hydration of carbon dioxide
FOB40_RS16600	COG2188	Transcriptional regulator
FOB40_RS16605	COG1228	amidohydrolase
FOB40_RS16610	COG0010	Belongs to the arginase family
FOB40_RS16615	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOB40_RS16620	COG2986	histidine ammonia-lyase
FOB40_RS16625	COG0387	Pfam Sodium calcium exchanger
FOB40_RS16630	COG2200	EAL domain
FOB40_RS16635	COG2199	diguanylate cyclase activity
FOB40_RS16635	COG2200	EAL domain
FOB40_RS16680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB40_RS16685	COG1459	type II secretion system
FOB40_RS16705	COG4968	Prepilin-type N-terminal cleavage methylation domain
FOB40_RS16730	COG1077	Cell shape determining protein MreB Mrl
FOB40_RS16735	COG1792	Involved in formation and maintenance of cell shape
FOB40_RS16740	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOB40_RS16745	COG0424	maF-like protein
FOB40_RS16750	COG1530	ribonuclease E activity
FOB40_RS16755	COG3164	Protein of unknown function
FOB40_RS16765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB40_RS16770	COG0312	modulator of DNA gyrase
FOB40_RS16785	COG0477	Major facilitator Superfamily
FOB40_RS16810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB40_RS16830	COG0189	ligase activity
FOB40_RS16840	COG0642	Histidine kinase
FOB40_RS16845	COG0745	RESPONSE REGULATOR receiver
FOB40_RS16865	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOB40_RS16870	COG0352	thiamine-phosphate diphosphorylase activity
FOB40_RS16875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB40_RS16885	COG2022	thiamine diphosphate biosynthetic process
FOB40_RS16890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOB40_RS16900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB40_RS16915	COG0583	DNA-binding transcription factor activity
FOB40_RS16920	COG1380	Effector of murein hydrolase LrgA
FOB40_RS16925	COG1346	cytolysis
FOB40_RS16935	COG4667	esterase of the alpha-beta hydrolase superfamily
FOB40_RS16940	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOB40_RS16945	COG1546	Belongs to the CinA family
FOB40_RS16950	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOB40_RS16960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB40_RS16965	COG0527	aspartate kinase activity
FOB40_RS16970	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FOB40_RS17005	COG1686	Belongs to the peptidase S11 family
FOB40_RS17010	COG0586	Pfam SNARE associated Golgi protein
FOB40_RS17015	COG1253	flavin adenine dinucleotide binding
FOB40_RS17020	COG0252	asparaginase activity
FOB40_RS17040	COG1263	PTS System
FOB40_RS17040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB40_RS17045	COG0366	Alpha amylase catalytic
FOB40_RS17050	COG0110	maltose O-acetyltransferase activity
FOB40_RS17060	COG0564	pseudouridine synthase activity
FOB40_RS17065	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOB40_RS17095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB40_RS17095	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB40_RS17110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOB40_RS17115	COG0038	chloride channel
FOB40_RS17125	COG0316	Belongs to the HesB IscA family
FOB40_RS17130	COG1757	Na H antiporter
FOB40_RS17170	COG0297	glycogen (starch) synthase activity
FOB40_RS17175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOB40_RS17180	COG2813	Specifically methylates the guanine in position
FOB40_RS17185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB40_RS17195	COG1392	Phosphate transport regulator
FOB40_RS17200	COG0306	phosphate transporter
FOB40_RS17205	COG0527	aspartate kinase activity
FOB40_RS17205	COG0460	homoserine dehydrogenase
FOB40_RS17210	COG0626	cystathionine gamma-synthase activity
FOB40_RS17225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB40_RS17230	COG0814	amino acid
FOB40_RS17235	COG1218	3'(2'),5'-bisphosphate nucleotidase
FOB40_RS17240	COG0494	nUDIX hydrolase
FOB40_RS17245	COG1011	Hydrolase
FOB40_RS17260	COG0110	maltose O-acetyltransferase activity
FOB40_RS17265	COG3174	membrane
FOB40_RS17270	COG3397	chitin binding
FOB40_RS17275	COG0840	transmembrane signaling receptor activity
FOB40_RS17290	COG1649	PFAM Uncharacterised BCR, COG1649
FOB40_RS17290	COG0726	polysaccharide deacetylase
FOB40_RS17295	COG1215	transferase activity, transferring glycosyl groups
FOB40_RS17305	COG0543	2 iron, 2 sulfur cluster binding
FOB40_RS17305	COG0633	Ferredoxin
FOB40_RS17330	COG1328	CTP reductase activity
FOB40_RS17335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB40_RS17350	COG1448	Aminotransferase
FOB40_RS17355	COG2194	sulfuric ester hydrolase activity
FOB40_RS17375	COG1215	transferase activity, transferring glycosyl groups
FOB40_RS17380	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOB40_RS17385	COG3118	belongs to the thioredoxin family
FOB40_RS17385	COG0457	Tetratricopeptide repeat
FOB40_RS17425	COG0513	Belongs to the DEAD box helicase family
FOB40_RS17455	COG3112	Uncharacterised protein family (UPF0231)
FOB40_RS17460	COG3835	regulator
FOB40_RS17465	COG2610	gluconate transmembrane transporter activity
FOB40_RS17470	COG1929	Belongs to the glycerate kinase type-1 family
FOB40_RS17485	COG0583	DNA-binding transcription factor activity
FOB40_RS17490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB40_RS17500	COG1872	DUF167
FOB40_RS17505	COG0762	integral membrane protein
FOB40_RS17510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOB40_RS17515	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB40_RS17530	COG3022	response to hydroperoxide
FOB40_RS17550	COG0347	Belongs to the P(II) protein family
FOB40_RS17555	COG1840	ABC-type Fe3 transport system, periplasmic component
FOB40_RS17565	COG3842	ATPase activity
FOB40_RS17570	COG2837	iron assimilation
FOB40_RS17575	COG1438	arginine binding
FOB40_RS17580	COG1126	abc transporter atp-binding protein
FOB40_RS17585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB40_RS17590	COG4215	(ABC) transporter
FOB40_RS17595	COG4160	amino acid transport
FOB40_RS17600	COG0039	L-malate dehydrogenase activity
FOB40_RS17605	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FOB40_RS17610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB40_RS17610	COG1017	nitric oxide dioxygenase activity
FOB40_RS17620	COG4536	flavin adenine dinucleotide binding
FOB40_RS17625	COG4137	Cytochrome C assembly protein
FOB40_RS17630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOB40_RS17635	COG0228	four-way junction DNA binding
FOB40_RS17640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOB40_RS17645	COG0336	Belongs to the RNA methyltransferase TrmD family
FOB40_RS17650	COG0335	large ribosomal subunit rRNA binding
FOB40_RS17660	COG3066	DNA modification
FOB40_RS17665	COG1051	belongs to the nudix hydrolase family
FOB40_RS17675	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOB40_RS17680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOB40_RS17685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOB40_RS17695	COG0583	DNA-binding transcription factor activity
FOB40_RS17700	COG0640	Transcriptional regulator
FOB40_RS17705	COG0268	Binds directly to 16S ribosomal RNA
FOB40_RS17710	COG0728	peptidoglycan biosynthetic process
FOB40_RS17715	COG0196	riboflavin kinase activity
FOB40_RS17720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB40_RS17725	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOB40_RS17730	COG1047	Peptidyl-prolyl cis-trans
FOB40_RS17735	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOB40_RS17780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB40_RS17780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOB40_RS17795	COG1854	S-ribosylhomocysteine lyase activity
FOB40_RS17805	COG2165	general secretion pathway protein
FOB40_RS17810	COG0084	hydrolase, TatD family'
FOB40_RS17815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB40_RS17825	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOB40_RS17830	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOB40_RS17835	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOB40_RS17850	COG0560	Phosphoserine phosphatase
FOB40_RS17865	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOB40_RS17880	COG0776	regulation of translation
FOB40_RS17890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB40_RS17895	COG1914	H( )-stimulated, divalent metal cation uptake system
FOB40_RS17900	COG0360	Binds together with S18 to 16S ribosomal RNA
FOB40_RS17905	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOB40_RS17910	COG0359	binds to the 23S rRNA
FOB40_RS17915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB40_RS17940	COG1064	alcohol dehydrogenase
FOB40_RS17945	COG1238	metal cluster binding
FOB40_RS17950	COG0612	Peptidase, M16
FOB40_RS17955	COG2918	glutathione biosynthetic process
FOB40_RS17960	COG1022	Amp-dependent synthetase and ligase
FOB40_RS17970	COG0456	acetyltransferase
FOB40_RS17985	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FOB40_RS17995	COG1028	Short-chain dehydrogenase reductase Sdr
FOB40_RS18010	COG0477	Major facilitator Superfamily
FOB40_RS18015	COG0583	DNA-binding transcription factor activity
FOB40_RS18025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB40_RS18030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB40_RS18040	COG0673	inositol 2-dehydrogenase activity
FOB40_RS18050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOB40_RS18055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB40_RS18060	COG3036	rescue of stalled ribosome
FOB40_RS18070	COG0138	bifunctional purine biosynthesis protein purh
FOB40_RS18075	COG0151	Belongs to the GarS family
FOB40_RS18095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOB40_RS18105	COG1610	YqeY-like protein
FOB40_RS18110	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOB40_RS18115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOB40_RS18120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOB40_RS18125	COG1027	Aspartate ammonia-lyase
FOB40_RS18130	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOB40_RS18135	COG0534	Mate efflux family protein
FOB40_RS18140	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOB40_RS18145	COG0459	protein refolding
FOB40_RS18195	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOB40_RS18200	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FOB40_RS18210	COG4143	(ABC) transporter
FOB40_RS18225	COG0066	3-isopropylmalate dehydratase activity
FOB40_RS18230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOB40_RS18235	COG0473	3-isopropylmalate dehydrogenase activity
FOB40_RS18240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB40_RS18265	COG0028	Belongs to the TPP enzyme family
FOB40_RS18275	COG0440	acetolactate synthase activity
FOB40_RS18310	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FOB40_RS18325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB40_RS18355	COG0745	RESPONSE REGULATOR receiver
FOB40_RS18360	COG3104	oligopeptide transport
FOB40_RS18365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOB40_RS18370	COG1555	photosystem II stabilization
FOB40_RS18375	COG0857	belongs to the CobB CobQ family
FOB40_RS18375	COG0280	phosphate acetyltransferase
FOB40_RS18380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB40_RS18390	COG3013	Belongs to the UPF0304 family
FOB40_RS18395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOB40_RS18400	COG2716	regulation of RNA biosynthetic process
FOB40_RS18405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB40_RS18410	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOB40_RS18415	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOB40_RS18450	COG5002	protein histidine kinase activity
FOB40_RS18450	COG2198	Histidine kinase
FOB40_RS18450	COG0784	Response regulator, receiver
FOB40_RS18455	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOB40_RS18485	COG1464	Belongs to the NlpA lipoprotein family
FOB40_RS18490	COG2011	ABC-type metal ion transport system permease component
FOB40_RS18495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB40_RS18515	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOB40_RS18515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOB40_RS18520	COG0802	atpase or kinase
FOB40_RS18530	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOB40_RS18535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOB40_RS18540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOB40_RS18545	COG1923	regulation of RNA biosynthetic process
FOB40_RS18550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOB40_RS18555	COG0330	HflC and HflK could
FOB40_RS18560	COG0330	HflC and HflK could
FOB40_RS18565	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FOB40_RS18570	COG0142	geranyltranstransferase activity
FOB40_RS18575	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOB40_RS18580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOB40_RS18585	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOB40_RS18590	COG3314	Sporulation integral membrane protein YlbJ
FOB40_RS18600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB40_RS18615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOB40_RS18620	COG2967	ApaG domain
FOB40_RS18625	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOB40_RS18630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOB40_RS18635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB40_RS18640	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOB40_RS18645	COG3178	'Phosphotransferase
FOB40_RS18650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOB40_RS18655	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOB40_RS18660	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOB40_RS18670	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FOB40_RS18675	COG1073	alpha beta
FOB40_RS18690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOB40_RS18705	COG4628	conserved protein (DUF2132)
FOB40_RS18710	COG0688	phosphatidylethanolamine metabolic process
FOB40_RS18715	COG1162	GTPase activity
FOB40_RS18720	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOB40_RS18760	COG1278	Cold shock
FOB40_RS18770	COG0840	transmembrane signaling receptor activity
FOB40_RS18775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB40_RS18780	COG2252	PERMEase
FOB40_RS18790	COG0488	(ABC) transporter
FOB40_RS18805	COG0741	lytic transglycosylase activity
FOB40_RS18815	COG3416	Protein conserved in bacteria
FOB40_RS18835	COG4608	Belongs to the ABC transporter superfamily
FOB40_RS18840	COG0444	Belongs to the ABC transporter superfamily
FOB40_RS18850	COG4239	(ABC) transporter, permease
FOB40_RS18855	COG4174	ABC transporter (Permease)
FOB40_RS18870	COG0811	peptide transport
FOB40_RS18875	COG0811	peptide transport
FOB40_RS18880	COG0848	biopolymer transport protein
FOB40_RS18900	COG0616	signal peptide processing
FOB40_RS18905	COG1902	pentaerythritol trinitrate reductase activity
FOB40_RS18905	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB40_RS18910	COG0778	Nitroreductase
FOB40_RS18925	COG2264	protein methyltransferase activity
FOB40_RS18930	COG0604	alcohol dehydrogenase
FOB40_RS18935	COG0583	DNA-binding transcription factor activity
FOB40_RS18940	COG2190	(PTS) system
FOB40_RS18940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB40_RS18940	COG1263	PTS System
FOB40_RS18945	COG4145	pantothenate transmembrane transporter activity
FOB40_RS18955	COG0439	Biotin carboxylase
FOB40_RS18960	COG0511	ligase activity, forming carbon-carbon bonds
FOB40_RS18965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOB40_RS18970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB40_RS18990	COG3381	protein complex oligomerization
FOB40_RS19000	COG3005	denitrification pathway
FOB40_RS19005	COG0745	RESPONSE REGULATOR receiver
FOB40_RS19015	COG1879	ABC-type sugar transport system periplasmic component
FOB40_RS19020	COG0784	Response regulator, receiver
FOB40_RS19020	COG2205	protein histidine kinase activity
FOB40_RS19020	COG2198	Histidine kinase
FOB40_RS19030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOB40_RS19035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOB40_RS19040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB40_RS19040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB40_RS19055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOB40_RS19060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB40_RS19065	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOB40_RS19070	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOB40_RS19085	COG0601	transmembrane transport
FOB40_RS19095	COG2900	Belongs to the SlyX family
FOB40_RS19105	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB40_RS19110	COG2204	response regulator
FOB40_RS19130	COG0737	Belongs to the 5'-nucleotidase family
FOB40_RS19135	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOB40_RS19140	COG0142	geranyltranstransferase activity
FOB40_RS19145	COG1722	exodeoxyribonuclease VII activity
FOB40_RS19150	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOB40_RS19155	COG1360	Flagellar Motor Protein
FOB40_RS19170	COG1534	Rna-binding protein
FOB40_RS19175	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FOB40_RS19185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOB40_RS19190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB40_RS19195	COG0149	triose-phosphate isomerase activity
FOB40_RS19200	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB40_RS19215	COG0779	Required for maturation of 30S ribosomal subunits
FOB40_RS19220	COG0195	Participates in both transcription termination and antitermination
FOB40_RS19225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOB40_RS19230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOB40_RS19235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOB40_RS19240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOB40_RS19245	COG1185	polyribonucleotide nucleotidyltransferase activity
FOB40_RS19250	COG2201	protein-glutamate methylesterase activity
FOB40_RS19255	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FOB40_RS19265	COG0840	transmembrane signaling receptor activity
FOB40_RS19270	COG0835	chemotaxis
FOB40_RS19280	COG0643	Histidine kinase
FOB40_RS19280	COG2198	Histidine kinase
FOB40_RS19290	COG0745	RESPONSE REGULATOR receiver
FOB40_RS19300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB40_RS19310	COG1280	lysine exporter protein (LysE YggA)
FOB40_RS19315	COG0826	peptidase U32
FOB40_RS19360	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOB40_RS19385	COG0300	oxidoreductase activity
FOB40_RS19395	COG0840	transmembrane signaling receptor activity
FOB40_RS19425	COG0077	Prephenate dehydratase
FOB40_RS19425	COG1605	Chorismate mutase
FOB40_RS19455	COG3272	Protein of unknown function (DUF1722)
FOB40_RS19460	COG0789	Transcriptional regulator
FOB40_RS19465	COG0415	Belongs to the DNA photolyase family
FOB40_RS19475	COG0300	oxidoreductase activity
FOB40_RS19490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOB40_RS19520	COG1477	protein flavinylation
FOB40_RS19525	COG2871	sodium ion transport
FOB40_RS19530	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB40_RS19535	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB40_RS19540	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB40_RS19545	COG1805	sodium ion transport
FOB40_RS19550	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOB40_RS19555	COG0271	Belongs to the BolA IbaG family
FOB40_RS19560	COG2813	Specifically methylates the guanine in position
FOB40_RS19570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB40_RS19575	COG2211	Major facilitator Superfamily
FOB40_RS19580	COG3248	Nucleoside-binding outer membrane protein
FOB40_RS19585	COG1666	GTP binding
FOB40_RS19590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOB40_RS19605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB40_RS19610	COG0840	transmembrane signaling receptor activity
FOB40_RS19615	COG0583	DNA-binding transcription factor activity
FOB40_RS19625	COG2363	Small membrane protein
FOB40_RS19630	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FOB40_RS19640	COG0473	3-isopropylmalate dehydrogenase activity
FOB40_RS19645	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB40_RS19650	COG1611	Belongs to the LOG family
FOB40_RS19665	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOB40_RS19665	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOB40_RS19675	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FOB40_RS19700	COG3098	single-species biofilm formation
FOB40_RS19705	COG0564	pseudouridine synthase activity
FOB40_RS19725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB40_RS19725	COG1263	PTS System
FOB40_RS19735	COG2171	N-acyltransferase activity
FOB40_RS19745	COG0024	Methionine aminopeptidase
FOB40_RS19750	COG0052	Belongs to the universal ribosomal protein uS2 family
FOB40_RS19755	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOB40_RS19760	COG0528	UMP kinase activity
FOB40_RS19765	COG0233	cytoplasmic translational termination
FOB40_RS19770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB40_RS19775	COG0575	Belongs to the CDS family
FOB40_RS19780	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOB40_RS19785	COG0750	zinc metalloprotease
FOB40_RS19790	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB40_RS19800	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB40_RS19805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB40_RS19810	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB40_RS19815	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB40_RS19820	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOB40_RS19830	COG0825	malonyl-CoA metabolic process
FOB40_RS19840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB40_RS19845	COG1115	amino acid carrier protein
FOB40_RS19860	COG0714	Associated with various cellular activities
FOB40_RS19875	COG3104	oligopeptide transport
FOB40_RS19880	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOB40_RS19885	COG1678	Uncharacterized ACR, COG1678
FOB40_RS19890	COG0189	ligase activity
FOB40_RS19895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB40_RS19905	COG3091	SprT-like family
FOB40_RS19915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB40_RS19935	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOB40_RS19940	COG0739	heme binding
FOB40_RS19945	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB40_RS19975	COG0814	amino acid
FOB40_RS19995	COG0531	amino acid
FOB40_RS20000	COG3710	Transcriptional regulator
FOB40_RS20010	COG0531	amino acid
FOB40_RS20015	COG1982	Orn Lys Arg decarboxylase major
FOB40_RS20020	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FOB40_RS20030	COG3590	peptidase
FOB40_RS20040	COG2203	Gaf domain
FOB40_RS20040	COG2199	diguanylate cyclase activity
FOB40_RS20075	COG0366	Alpha amylase catalytic
FOB40_RS20090	COG0463	Glycosyl transferase, family 2
FOB40_RS20105	COG2989	Protein conserved in bacteria
FOB40_RS20110	COG3108	Peptidase M15
FOB40_RS20120	COG2860	membrane
FOB40_RS20130	COG1196	nuclear chromosome segregation
FOB40_RS20135	COG3115	cell septum assembly
FOB40_RS20140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOB40_RS20155	COG1328	CTP reductase activity
FOB40_RS20160	COG0602	queuosine metabolic process
FOB40_RS20190	COG1566	PFAM secretion protein HlyD family protein
FOB40_RS20195	COG1846	Transcriptional regulator
FOB40_RS20210	COG0281	malic enzyme
FOB40_RS20215	COG3290	protein histidine kinase activity
FOB40_RS20225	COG0697	spore germination
FOB40_RS20240	COG3284	Transcriptional regulator
FOB40_RS20245	COG0346	lactoylglutathione lyase activity
FOB40_RS20250	COG0745	RESPONSE REGULATOR receiver
FOB40_RS20255	COG5002	protein histidine kinase activity
FOB40_RS20280	COG3142	Participates in the control of copper homeostasis
FOB40_RS20285	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB40_RS20310	COG0678	peroxiredoxin activity
FOB40_RS20320	COG0019	diaminopimelate decarboxylase activity
FOB40_RS20325	COG1115	amino acid carrier protein
FOB40_RS20330	COG0095	Lipoate-protein ligase
FOB40_RS20335	COG2233	PERMEase
FOB40_RS20350	COG0534	Mate efflux family protein
FOB40_RS20360	COG0281	malic enzyme
FOB40_RS20390	COG0531	amino acid
FOB40_RS20395	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOB40_RS20400	COG3706	GGDEF domain
FOB40_RS20405	COG1566	PFAM secretion protein HlyD family protein
FOB40_RS20415	COG1032	radical SAM domain protein
FOB40_RS20440	COG0583	DNA-binding transcription factor activity
FOB40_RS20445	COG0673	inositol 2-dehydrogenase activity
FOB40_RS20450	COG2920	part of a sulfur-relay system
FOB40_RS20455	COG1289	transmembrane transporter activity
FOB40_RS20460	COG0670	Belongs to the BI1 family
FOB40_RS20475	COG1486	melibiose metabolic process
FOB40_RS20480	COG1917	Cupin 2, conserved barrel domain protein
FOB40_RS20480	COG2169	Transcriptional regulator
FOB40_RS20485	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB40_RS20490	COG2723	6-phospho-beta-galactosidase activity
FOB40_RS20495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB40_RS20500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB40_RS20510	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FOB40_RS20520	COG3156	type II secretion system protein K
FOB40_RS20525	COG4795	General secretion pathway protein
FOB40_RS20530	COG2165	general secretion pathway protein
FOB40_RS20540	COG2165	general secretion pathway protein
FOB40_RS20545	COG1459	type II secretion system
FOB40_RS20550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB40_RS20560	COG3031	protein transport across the cell outer membrane
FOB40_RS20570	COG3267	Type II secretory pathway component ExeA
FOB40_RS20570	COG3409	Peptidoglycan-binding domain 1 protein
FOB40_RS20575	COG3437	response regulator, receiver
FOB40_RS20575	COG2770	Histidine kinase
FOB40_RS20590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB40_RS20595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOB40_RS20600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB40_RS20610	COG2190	(PTS) system
FOB40_RS20620	COG3590	peptidase
FOB40_RS20630	COG1196	nuclear chromosome segregation
FOB40_RS20630	COG3264	Mechanosensitive ion channel
FOB40_RS20635	COG0469	pyruvate kinase activity
FOB40_RS20645	COG3384	dioxygenase
FOB40_RS20650	COG0419	ATPase involved in DNA repair
FOB40_RS20655	COG0420	3'-5' exonuclease activity
FOB40_RS20665	COG2974	May be involved in recombination
FOB40_RS20675	COG0545	Peptidyl-prolyl cis-trans isomerase
FOB40_RS20680	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOB40_RS20685	COG0531	amino acid
FOB40_RS20695	COG0531	amino acid
FOB40_RS20710	COG1396	sequence-specific DNA binding
FOB40_RS20710	COG1917	Cupin 2, conserved barrel domain protein
FOB40_RS20715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB40_RS20755	COG3038	cytochrome b561
FOB40_RS20760	COG1720	tRNA m6t6A37 methyltransferase activity
FOB40_RS20780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOB40_RS20785	COG4988	ABC transporter
FOB40_RS20800	COG0745	RESPONSE REGULATOR receiver
FOB40_RS20810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB40_RS20840	COG0798	PFAM Bile acid sodium symporter
FOB40_RS20850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOB40_RS20870	COG1988	membrane-bound metal-dependent
FOB40_RS20890	COG0159	tryptophan synthase activity
FOB40_RS20895	COG0133	tryptophan synthase activity
FOB40_RS20900	COG0134	indole-3-glycerol-phosphate synthase activity
FOB40_RS20900	COG0135	phosphoribosylanthranilate isomerase activity
FOB40_RS20905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB40_RS20910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB40_RS20910	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB40_RS20915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB40_RS20925	COG0009	L-threonylcarbamoyladenylate synthase
FOB40_RS20935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOB40_RS20945	COG1946	Acyl-CoA thioesterase
FOB40_RS20950	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FOB40_RS20955	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FOB40_RS20970	COG0083	homoserine kinase activity
FOB40_RS20975	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOB40_RS20985	COG1943	Transposase
FOB40_RS21000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOB40_RS21020	COG1342	Belongs to the UPF0251 family