locus-tag	class	description
KW556_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KW556_RS00010	COG0592	DNA-directed DNA polymerase activity
KW556_RS00020	COG0187	DNA topoisomerase II activity
KW556_RS00030	COG2378	regulation of single-species biofilm formation
KW556_RS00040	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KW556_RS00045	COG0071	Belongs to the small heat shock protein (HSP20) family
KW556_RS00050	COG0071	Belongs to the small heat shock protein (HSP20) family
KW556_RS00055	COG3977	Valine--pyruvate aminotransferase
KW556_RS00070	COG2814	Major facilitator Superfamily
KW556_RS00075	COG0745	RESPONSE REGULATOR receiver
KW556_RS00080	COG2205	protein histidine kinase activity
KW556_RS00100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KW556_RS00105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW556_RS00105	COG4191	Histidine kinase
KW556_RS00110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KW556_RS00115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW556_RS00120	COG1309	transcriptional regulator
KW556_RS00150	COG0469	pyruvate kinase activity
KW556_RS00155	COG2271	Major facilitator Superfamily
KW556_RS00185	COG0561	phosphatase activity
KW556_RS00190	COG2267	carboxylic ester hydrolase activity
KW556_RS00200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KW556_RS00205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KW556_RS00210	COG1758	RNA polymerase activity
KW556_RS00215	COG0194	GDP metabolic process
KW556_RS00220	COG0859	PFAM glycosyl transferase family 9
KW556_RS00225	COG3642	lipopolysaccharide core region biosynthetic process
KW556_RS00265	COG0589	response to stress
KW556_RS00270	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KW556_RS00275	COG1528	Iron-storage protein
KW556_RS00280	COG2081	HI0933 family
KW556_RS00285	COG3275	phosphorelay sensor kinase activity
KW556_RS00290	COG3279	Response regulator of the LytR AlgR family
KW556_RS00295	COG2223	nitrite transmembrane transporter activity
KW556_RS00300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KW556_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KW556_RS00320	COG0583	DNA-binding transcription factor activity
KW556_RS00330	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KW556_RS00365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KW556_RS00370	COG2166	iron-sulfur cluster assembly
KW556_RS00375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KW556_RS00390	COG3245	cytochrome
KW556_RS00395	COG1063	alcohol dehydrogenase
KW556_RS00410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KW556_RS00425	COG3307	-O-antigen
KW556_RS00430	COG3306	glycosyltransferase involved in LPS biosynthesis
KW556_RS00470	COG1280	lysine exporter protein (LysE YggA)
KW556_RS00515	COG1943	Transposase
KW556_RS00540	COG1484	DNA-dependent DNA replication
KW556_RS00545	COG4584	PFAM Integrase catalytic
KW556_RS00560	COG0210	DNA helicase
KW556_RS00565	COG1744	ABC transporter substrate-binding protein PnrA-like
KW556_RS00570	COG3845	ABC transporter
KW556_RS00575	COG4603	Belongs to the binding-protein-dependent transport system permease family
KW556_RS00580	COG1079	Belongs to the binding-protein-dependent transport system permease family
KW556_RS00585	COG0737	Belongs to the 5'-nucleotidase family
KW556_RS00595	COG2239	Acts as a magnesium transporter
KW556_RS00600	COG1648	precorrin-2 dehydrogenase activity
KW556_RS00600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KW556_RS00605	COG2116	formate transmembrane transporter activity
KW556_RS00620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KW556_RS00625	COG0842	Transport permease protein
KW556_RS00630	COG0842	Transport permease protein
KW556_RS00635	COG1131	(ABC) transporter
KW556_RS00640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW556_RS00650	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KW556_RS00655	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KW556_RS00665	COG0018	arginyl-trna synthetase
KW556_RS00675	COG1595	DNA-templated transcription, initiation
KW556_RS00685	COG1968	undecaprenyl-diphosphatase activity
KW556_RS00690	COG2017	converts alpha-aldose to the beta-anomer
KW556_RS00695	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KW556_RS00700	COG1085	galactose-1-phosphate uridylyltransferase
KW556_RS00705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KW556_RS00710	COG1609	Transcriptional regulator
KW556_RS00715	COG3250	beta-galactosidase activity
KW556_RS00725	COG1129	ABC transporter
KW556_RS00730	COG4211	Belongs to the binding-protein-dependent transport system permease family
KW556_RS00735	COG0840	transmembrane signaling receptor activity
KW556_RS00740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KW556_RS00755	COG0366	Alpha amylase catalytic
KW556_RS00770	COG0443	Heat shock 70 kDa protein
KW556_RS00775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KW556_RS00780	COG3045	CreA protein
KW556_RS00800	COG0174	glutamine synthetase
KW556_RS00820	COG3842	ATPase activity
KW556_RS00825	COG1176	ABC-type spermidine putrescine transport system, permease component I
KW556_RS00830	COG1177	transmembrane transport
KW556_RS00835	COG2258	MOSC domain
KW556_RS00850	COG2050	protein possibly involved in aromatic compounds catabolism
KW556_RS00855	COG0514	ATP-dependent DNA helicase (RecQ)
KW556_RS00865	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KW556_RS00875	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KW556_RS00880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KW556_RS00895	COG0254	rRNA binding
KW556_RS00900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KW556_RS00910	COG0702	epimerase
KW556_RS00915	COG0814	amino acid
KW556_RS00920	COG0281	malic enzyme
KW556_RS00925	COG1295	ribonuclease BN
KW556_RS00930	COG1490	D-aminoacyl-tRNA deacylase activity
KW556_RS00935	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KW556_RS00940	COG0456	acetyltransferase
KW556_RS00950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KW556_RS00955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KW556_RS00970	COG3265	gluconokinase activity
KW556_RS00975	COG0129	dihydroxy-acid dehydratase activity
KW556_RS00980	COG0800	Aldolase
KW556_RS00985	COG1609	Transcriptional regulator
KW556_RS00995	COG4942	peptidase
KW556_RS01000	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KW556_RS01005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KW556_RS01010	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KW556_RS01015	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KW556_RS01020	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KW556_RS01020	COG0316	Belongs to the HesB IscA family
KW556_RS01025	COG1040	competence protein
KW556_RS01030	COG0596	Alpha beta hydrolase
KW556_RS01050	COG2183	response to ionizing radiation
KW556_RS01055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KW556_RS01075	COG0051	transcription antitermination factor activity, RNA binding
KW556_RS01080	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KW556_RS01085	COG0088	Forms part of the polypeptide exit tunnel
KW556_RS01090	COG0089	rRNA binding
KW556_RS01095	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KW556_RS01100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KW556_RS01105	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KW556_RS01110	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KW556_RS01115	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KW556_RS01120	COG0255	Belongs to the universal ribosomal protein uL29 family
KW556_RS01125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KW556_RS01130	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KW556_RS01135	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KW556_RS01140	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KW556_RS01145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KW556_RS01150	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KW556_RS01155	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KW556_RS01160	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KW556_RS01165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KW556_RS01170	COG1841	ribosomal large subunit assembly
KW556_RS01175	COG0200	Binds to the 23S rRNA
KW556_RS01180	COG0201	protein transport
KW556_RS01185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KW556_RS01190	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KW556_RS01195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KW556_RS01200	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KW556_RS01205	COG0202	RNA polymerase activity
KW556_RS01210	COG0203	ribosomal protein L17
KW556_RS01245	COG4771	TonB-dependent receptor
KW556_RS01250	COG3706	GGDEF domain
KW556_RS01270	COG0840	transmembrane signaling receptor activity
KW556_RS01280	COG0583	DNA-binding transcription factor activity
KW556_RS01285	COG1741	Belongs to the pirin family
KW556_RS01290	COG2259	Doxx family
KW556_RS01295	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KW556_RS01300	COG1074	ATP-dependent DNA helicase activity
KW556_RS01305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KW556_RS01350	COG1175	transmembrane transport
KW556_RS01360	COG3842	ATPase activity
KW556_RS01390	COG2873	o-acetylhomoserine
KW556_RS01400	COG4533	DNA binding
KW556_RS01420	COG5380	lipid catabolic process
KW556_RS01425	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KW556_RS01430	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KW556_RS01455	COG0753	catalase activity
KW556_RS01485	COG2927	DNA polymerase III (CHI subunit)
KW556_RS01490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KW556_RS01495	COG0795	lipopolysaccharide-transporting ATPase activity
KW556_RS01500	COG0795	lipopolysaccharide-transporting ATPase activity
KW556_RS01560	COG0582	viral genome integration into host DNA
KW556_RS01575	COG3561	AntA/AntB antirepressor
KW556_RS01665	COG1494	fructose-1,6-bisphosphatase
KW556_RS01680	COG2959	enzyme of heme biosynthesis
KW556_RS01690	COG0181	hydroxymethylbilane synthase activity
KW556_RS01695	COG3072	Adenylate cyclase
KW556_RS01700	COG0400	carboxylic ester hydrolase activity
KW556_RS01705	COG1965	Belongs to the frataxin family
KW556_RS01715	COG0019	diaminopimelate decarboxylase activity
KW556_RS01720	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KW556_RS01735	COG1011	Hydrolase
KW556_RS01755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KW556_RS01760	COG3028	Belongs to the UPF0307 family
KW556_RS01765	COG0312	modulator of DNA gyrase
KW556_RS01770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KW556_RS01775	COG5007	Belongs to the BolA IbaG family
KW556_RS01785	COG2854	intermembrane phospholipid transfer
KW556_RS01790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KW556_RS01795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KW556_RS01800	COG1127	ABC transporter
KW556_RS01805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KW556_RS01805	COG0517	IMP dehydrogenase activity
KW556_RS01810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KW556_RS01815	COG3117	lipopolysaccharide transmembrane transporter activity
KW556_RS01820	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KW556_RS01825	COG1137	ATPase activity
KW556_RS01840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW556_RS01845	COG1660	Displays ATPase and GTPase activities
KW556_RS01850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW556_RS01855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW556_RS01855	COG3711	transcriptional antiterminator
KW556_RS01870	COG3964	amidohydrolase
KW556_RS01900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KW556_RS01905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KW556_RS01915	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KW556_RS01920	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KW556_RS01925	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KW556_RS01930	COG0723	plastoquinol--plastocyanin reductase activity
KW556_RS01935	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KW556_RS01940	COG2857	Cytochrome c1
KW556_RS01945	COG0625	glutathione transferase activity
KW556_RS01950	COG2969	positive regulation of protein catabolic process
KW556_RS01955	COG2823	Periplasmic or secreted lipoprotein
KW556_RS01960	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KW556_RS01965	COG0792	nuclease activity
KW556_RS01970	COG3107	peptidoglycan biosynthetic process
KW556_RS01975	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KW556_RS02000	COG1987	bacterial-type flagellum assembly
KW556_RS02025	COG1677	Flagellar hook-basal body complex protein FliE
KW556_RS02035	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KW556_RS02070	COG1815	bacterial-type flagellum-dependent cell motility
KW556_RS02090	COG4787	bacterial-type flagellum-dependent cell motility
KW556_RS02095	COG4786	Flagellar basal body rod
KW556_RS02100	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KW556_RS02105	COG1706	bacterial-type flagellum-dependent cell motility
KW556_RS02115	COG1256	bacterial-type flagellum assembly
KW556_RS02115	COG4786	Flagellar basal body rod
KW556_RS02120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KW556_RS02135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KW556_RS02140	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KW556_RS02165	COG1191	sigma factor activity
KW556_RS02170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KW556_RS02185	COG1388	LysM domain
KW556_RS02185	COG0741	lytic transglycosylase activity
KW556_RS02190	COG2001	Belongs to the MraZ family
KW556_RS02195	COG0275	rRNA processing
KW556_RS02200	COG3116	cell division
KW556_RS02205	COG0768	penicillin binding
KW556_RS02215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KW556_RS02220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KW556_RS02225	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KW556_RS02230	COG0772	Belongs to the SEDS family
KW556_RS02235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KW556_RS02240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KW556_RS02250	COG0849	cell division
KW556_RS02255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KW556_RS02260	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KW556_RS02270	COG0653	protein targeting
KW556_RS02275	COG0494	nUDIX hydrolase
KW556_RS02280	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KW556_RS02285	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KW556_RS02300	COG1459	type II secretion system
KW556_RS02305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KW556_RS02330	COG2186	Transcriptional regulator
KW556_RS02335	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KW556_RS02340	COG0508	dehydrogenase complex catalyzes the overall conversion of
KW556_RS02345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KW556_RS02355	COG0840	transmembrane signaling receptor activity
KW556_RS02360	COG1752	Esterase of the alpha-beta hydrolase superfamily
KW556_RS02365	COG1049	propionate catabolic process, 2-methylcitrate cycle
KW556_RS02370	COG2200	EAL domain
KW556_RS02380	COG0523	cobalamin synthesis protein
KW556_RS02385	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KW556_RS02415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KW556_RS02420	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KW556_RS02480	COG2314	TM2 domain
KW556_RS02530	COG3314	Sporulation integral membrane protein YlbJ
KW556_RS02555	COG0165	Argininosuccinate lyase
KW556_RS02560	COG0137	argininosuccinate synthase activity
KW556_RS02570	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KW556_RS02575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KW556_RS02585	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KW556_RS02590	COG3385	transposase activity
KW556_RS02605	COG3706	GGDEF domain
KW556_RS02610	COG0814	amino acid
KW556_RS02615	COG3932	Exopolysaccharide synthesis, ExoD
KW556_RS02630	COG0004	ammonium transporteR
KW556_RS02635	COG3133	Outer membrane lipoprotein
KW556_RS02640	COG0456	acetyltransferase
KW556_RS02660	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KW556_RS02665	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KW556_RS02680	COG0494	nUDIX hydrolase
KW556_RS02685	COG0628	permease
KW556_RS02695	COG3284	Transcriptional regulator
KW556_RS02705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KW556_RS02705	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
KW556_RS02705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW556_RS02710	COG1461	Dihydroxyacetone kinase
KW556_RS02715	COG2376	Dihydroxyacetone kinase
KW556_RS02720	COG2252	PERMEase
KW556_RS02725	COG1278	Cold shock
KW556_RS02740	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KW556_RS02760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KW556_RS02770	COG3047	cAMP biosynthetic process
KW556_RS02775	COG0840	transmembrane signaling receptor activity
KW556_RS02800	COG3135	benzoate transporter
KW556_RS02805	COG1396	sequence-specific DNA binding
KW556_RS02880	COG0582	viral genome integration into host DNA
KW556_RS02885	COG0582	viral genome integration into host DNA
KW556_RS02930	COG3206	protein involved in exopolysaccharide biosynthesis
KW556_RS02930	COG0489	protein tyrosine kinase activity
KW556_RS02950	COG0438	transferase activity, transferring glycosyl groups
KW556_RS02975	COG1442	glycosyl transferase family 8
KW556_RS02995	COG3039	Transposase
KW556_RS03000	COG5433	transposase activity
KW556_RS03015	COG4983	Phage plasmid primase, P4 family domain protein
KW556_RS03035	COG5377	YqaJ viral recombinase family
KW556_RS03065	COG2003	Belongs to the UPF0758 family
KW556_RS03135	COG3318	Belongs to the UPF0149 family
KW556_RS03135	COG3012	SEC-C Motif Domain Protein
KW556_RS03145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KW556_RS03145	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KW556_RS03160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KW556_RS03165	COG0038	chloride channel
KW556_RS03175	COG0316	Belongs to the HesB IscA family
KW556_RS03180	COG1757	Na H antiporter
KW556_RS03220	COG0297	glycogen (starch) synthase activity
KW556_RS03225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KW556_RS03230	COG2813	Specifically methylates the guanine in position
KW556_RS03235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KW556_RS03245	COG1392	Phosphate transport regulator
KW556_RS03250	COG0306	phosphate transporter
KW556_RS03255	COG0527	aspartate kinase activity
KW556_RS03255	COG0460	homoserine dehydrogenase
KW556_RS03260	COG0626	cystathionine gamma-synthase activity
KW556_RS03275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KW556_RS03280	COG0814	amino acid
KW556_RS03290	COG1218	3'(2'),5'-bisphosphate nucleotidase
KW556_RS03295	COG0494	nUDIX hydrolase
KW556_RS03300	COG1011	Hydrolase
KW556_RS03315	COG0110	maltose O-acetyltransferase activity
KW556_RS03320	COG3174	membrane
KW556_RS03325	COG3397	chitin binding
KW556_RS03330	COG0840	transmembrane signaling receptor activity
KW556_RS03340	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KW556_RS03360	COG4783	chaperone-mediated protein folding
KW556_RS03375	COG0726	polysaccharide deacetylase
KW556_RS03375	COG1649	PFAM Uncharacterised BCR, COG1649
KW556_RS03380	COG1215	transferase activity, transferring glycosyl groups
KW556_RS03420	COG1328	CTP reductase activity
KW556_RS03425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KW556_RS03440	COG1448	Aminotransferase
KW556_RS03455	COG1842	Phage shock protein A
KW556_RS03470	COG2827	Endonuclease containing a URI domain
KW556_RS03485	COG1573	uracil-dna glycosylase
KW556_RS03490	COG0697	spore germination
KW556_RS03495	COG0583	DNA-binding transcription factor activity
KW556_RS03500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KW556_RS03505	COG1121	(ABC) transporter
KW556_RS03510	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KW556_RS03530	COG0739	heme binding
KW556_RS03540	COG3068	Protein conserved in bacteria
KW556_RS03560	COG0617	tRNA 3'-terminal CCA addition
KW556_RS03565	COG1194	a g-specific adenine glycosylase
KW556_RS03570	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KW556_RS03580	COG3111	PFAM Bacterial OB fold (BOF) protein
KW556_RS03585	COG3240	lipase activity
KW556_RS03590	COG2885	chlorophyll binding
KW556_RS03590	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KW556_RS03595	COG3706	GGDEF domain
KW556_RS03600	COG0557	exoribonuclease II activity
KW556_RS03605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KW556_RS03615	COG2153	protein acetylation
KW556_RS03620	COG0513	Belongs to the DEAD box helicase family
KW556_RS03625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KW556_RS03650	COG0735	belongs to the Fur family
KW556_RS03655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KW556_RS03660	COG0840	transmembrane signaling receptor activity
KW556_RS03670	COG4166	transmembrane transport
KW556_RS03680	COG0110	maltose O-acetyltransferase activity
KW556_RS03690	COG1024	Enoyl-CoA hydratase
KW556_RS03705	COG4221	oxidoreductase activity
KW556_RS03710	COG0442	prolyl-tRNA aminoacylation
KW556_RS03715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KW556_RS03720	COG3385	transposase activity
KW556_RS03730	COG3008	intermembrane lipid transfer
KW556_RS03730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KW556_RS03735	COG2995	paraquat-inducible protein a
KW556_RS03745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KW556_RS03755	COG5001	Diguanylate cyclase
KW556_RS03755	COG3706	GGDEF domain
KW556_RS03755	COG2203	Gaf domain
KW556_RS03755	COG4251	negative regulation of phosphorylation
KW556_RS03760	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
KW556_RS03775	COG2771	luxR family
KW556_RS03785	COG0840	transmembrane signaling receptor activity
KW556_RS03790	COG0632	four-way junction helicase activity
KW556_RS03795	COG2255	four-way junction helicase activity
KW556_RS03805	COG1294	oxidase, subunit
KW556_RS03810	COG4890	Cyd operon protein YbgT
KW556_RS03815	COG3790	cyd operon protein YbgE
KW556_RS03820	COG0824	Thioesterase
KW556_RS03825	COG0811	peptide transport
KW556_RS03840	COG0823	Involved in the tonB-independent uptake of proteins
KW556_RS03845	COG2885	chlorophyll binding
KW556_RS03850	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KW556_RS03920	COG0733	neurotransmitter:sodium symporter activity
KW556_RS03930	COG0733	neurotransmitter:sodium symporter activity
KW556_RS03945	COG0561	phosphatase activity
KW556_RS03995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KW556_RS04000	COG1640	4-alpha-glucanotransferase
KW556_RS04005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KW556_RS04010	COG0676	glucose-6-phosphate 1-epimerase activity
KW556_RS04015	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KW556_RS04020	COG0840	transmembrane signaling receptor activity
KW556_RS04025	COG1585	Membrane protein implicated in regulation of membrane protease activity
KW556_RS04030	COG0330	HflC and HflK could
KW556_RS04035	COG1648	precorrin-2 dehydrogenase activity
KW556_RS04035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KW556_RS04040	COG0175	sulfate reduction
KW556_RS04045	COG2895	sulfate adenylyltransferase (ATP) activity
KW556_RS04050	COG3273	potassium ion transport
KW556_RS04050	COG0471	metal ion transport
KW556_RS04055	COG0529	Catalyzes the synthesis of activated sulfate
KW556_RS04065	COG2357	RelA SpoT domain protein
KW556_RS04070	COG0840	transmembrane signaling receptor activity
KW556_RS04090	COG1136	(ABC) transporter
KW556_RS04105	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KW556_RS04120	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KW556_RS04125	COG3437	response regulator, receiver
KW556_RS04125	COG0784	Response regulator, receiver
KW556_RS04135	COG2076	Multidrug Resistance protein
KW556_RS04140	COG2076	Multidrug Resistance protein
KW556_RS04145	COG0346	lactoylglutathione lyase activity
KW556_RS04150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KW556_RS04155	COG1643	Atp-dependent helicase
KW556_RS04165	COG1489	DNA binding
KW556_RS04170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KW556_RS04175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KW556_RS04185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KW556_RS04190	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KW556_RS04195	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KW556_RS04205	COG1823	symporter activity
KW556_RS04225	COG1924	4 iron, 4 sulfur cluster binding
KW556_RS04230	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
KW556_RS04235	COG0842	Transport permease protein
KW556_RS04240	COG1131	(ABC) transporter
KW556_RS04255	COG0163	prenyltransferase activity
KW556_RS04260	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KW556_RS04265	COG0671	phosphoesterase, PA-phosphatase related
KW556_RS04270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KW556_RS04280	COG1151	hydroxylamine reductase activity
KW556_RS04285	COG0783	Belongs to the Dps family
KW556_RS04290	COG3023	N-Acetylmuramoyl-L-alanine amidase
KW556_RS04295	COG4807	Protein conserved in bacteria
KW556_RS04305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KW556_RS04310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KW556_RS04315	COG3956	TIGRFAM MazG family protein
KW556_RS04320	COG0504	CTP synthase activity
KW556_RS04325	COG0148	phosphopyruvate hydratase activity
KW556_RS04390	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KW556_RS04400	COG0488	(ABC) transporter
KW556_RS04405	COG0617	tRNA 3'-terminal CCA addition
KW556_RS04405	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KW556_RS04405	COG0517	IMP dehydrogenase activity
KW556_RS04420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KW556_RS04435	COG1794	racemase activity, acting on amino acids and derivatives
KW556_RS04445	COG2731	YhcH YjgK YiaL family protein
KW556_RS04455	COG0668	transmembrane transport
KW556_RS04460	COG1376	ErfK ybiS ycfS ynhG family protein
KW556_RS04470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KW556_RS04475	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KW556_RS04480	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KW556_RS04490	COG0585	pseudouridine synthase activity
KW556_RS04495	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KW556_RS04500	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KW556_RS04505	COG1238	metal cluster binding
KW556_RS04520	COG1902	pentaerythritol trinitrate reductase activity
KW556_RS04535	COG2957	Belongs to the agmatine deiminase family
KW556_RS04540	COG0154	amidase activity
KW556_RS04570	COG0513	Belongs to the DEAD box helicase family
KW556_RS04575	COG2199	diguanylate cyclase activity
KW556_RS04575	COG2203	Gaf domain
KW556_RS04585	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
KW556_RS04640	COG2205	protein histidine kinase activity
KW556_RS04665	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KW556_RS04670	COG2252	PERMEase
KW556_RS04680	COG0488	(ABC) transporter
KW556_RS04695	COG0741	lytic transglycosylase activity
KW556_RS04710	COG3416	Protein conserved in bacteria
KW556_RS04730	COG4608	Belongs to the ABC transporter superfamily
KW556_RS04735	COG0444	Belongs to the ABC transporter superfamily
KW556_RS04745	COG4239	(ABC) transporter, permease
KW556_RS04750	COG4174	ABC transporter (Permease)
KW556_RS04760	COG0616	signal peptide processing
KW556_RS04765	COG1902	pentaerythritol trinitrate reductase activity
KW556_RS04765	COG0446	pyridine nucleotide-disulphide oxidoreductase
KW556_RS04770	COG0778	Nitroreductase
KW556_RS04780	COG2264	protein methyltransferase activity
KW556_RS04785	COG0604	alcohol dehydrogenase
KW556_RS04790	COG0583	DNA-binding transcription factor activity
KW556_RS04795	COG2190	(PTS) system
KW556_RS04795	COG1263	PTS System
KW556_RS04795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KW556_RS04800	COG4145	pantothenate transmembrane transporter activity
KW556_RS04805	COG3924	membrane
KW556_RS04810	COG0439	Biotin carboxylase
KW556_RS04815	COG0511	ligase activity, forming carbon-carbon bonds
KW556_RS04820	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KW556_RS04825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KW556_RS04845	COG3381	protein complex oligomerization
KW556_RS04855	COG3005	denitrification pathway
KW556_RS04860	COG0745	RESPONSE REGULATOR receiver
KW556_RS04870	COG1879	ABC-type sugar transport system periplasmic component
KW556_RS04875	COG0784	Response regulator, receiver
KW556_RS04875	COG2198	Histidine kinase
KW556_RS04875	COG2205	protein histidine kinase activity
KW556_RS04885	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KW556_RS04890	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KW556_RS04895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KW556_RS04895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KW556_RS04910	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KW556_RS04915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KW556_RS04920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KW556_RS04925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KW556_RS04940	COG0601	transmembrane transport
KW556_RS04950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KW556_RS04955	COG0142	geranyltranstransferase activity
KW556_RS04960	COG1722	exodeoxyribonuclease VII activity
KW556_RS04965	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KW556_RS04970	COG1360	Flagellar Motor Protein
KW556_RS04985	COG1534	Rna-binding protein
KW556_RS04990	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KW556_RS05000	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KW556_RS05005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KW556_RS05010	COG0149	triose-phosphate isomerase activity
KW556_RS05015	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KW556_RS05030	COG0779	Required for maturation of 30S ribosomal subunits
KW556_RS05035	COG0195	Participates in both transcription termination and antitermination
KW556_RS05040	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KW556_RS05045	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KW556_RS05050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KW556_RS05055	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KW556_RS05060	COG1185	polyribonucleotide nucleotidyltransferase activity
KW556_RS05065	COG3655	Transcriptional regulator
KW556_RS05075	COG2205	protein histidine kinase activity
KW556_RS05075	COG5002	protein histidine kinase activity
KW556_RS05075	COG0784	Response regulator, receiver
KW556_RS05085	COG3706	GGDEF domain
KW556_RS05135	COG0784	Response regulator, receiver
KW556_RS05135	COG0835	chemotaxis
KW556_RS05140	COG2755	lipolytic protein G-D-S-L family
KW556_RS05145	COG4181	ATPase activity
KW556_RS05150	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KW556_RS05155	COG1090	epimerase
KW556_RS05160	COG2200	EAL domain
KW556_RS05165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KW556_RS05170	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KW556_RS05175	COG3171	Protein conserved in bacteria
KW556_RS05180	COG2066	Belongs to the glutaminase family
KW556_RS05185	COG2897	thiosulfate sulfurtransferase activity
KW556_RS05200	COG0521	Mo-molybdopterin cofactor biosynthetic process
KW556_RS05215	COG2966	Psort location CytoplasmicMembrane, score
KW556_RS05220	COG3610	response to peptide
KW556_RS05235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KW556_RS05240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KW556_RS05245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KW556_RS05260	COG0786	glutamate:sodium symporter activity
KW556_RS05265	COG0252	asparaginase activity
KW556_RS05270	COG3139	Protein of unknown function (DUF1315)
KW556_RS05290	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KW556_RS05295	COG0321	lipoyl(octanoyl) transferase activity
KW556_RS05300	COG2921	Belongs to the UPF0250 family
KW556_RS05305	COG1686	Belongs to the peptidase S11 family
KW556_RS05310	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KW556_RS05315	COG2951	lytic endotransglycosylase activity
KW556_RS05320	COG0772	Belongs to the SEDS family
KW556_RS05325	COG0768	penicillin binding
KW556_RS05330	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KW556_RS05335	COG0799	negative regulation of ribosome biogenesis
KW556_RS05340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KW556_RS05355	COG0495	leucyl-tRNA aminoacylation
KW556_RS05360	COG2888	peptidyl-tyrosine sulfation
KW556_RS05365	COG0312	modulator of DNA gyrase
KW556_RS05370	COG0312	modulator of DNA gyrase
KW556_RS05375	COG0716	FMN binding
KW556_RS05380	COG4974	Belongs to the 'phage' integrase family
KW556_RS05385	COG1970	mechanosensitive ion channel activity
KW556_RS05400	COG0789	Transcriptional regulator
KW556_RS05405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KW556_RS05410	COG4535	Mg2 and Co2 transporter CorC
KW556_RS05415	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KW556_RS05420	COG1702	phosphate starvation-inducible protein PhoH
KW556_RS05425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KW556_RS05430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KW556_RS05435	COG1335	isochorismatase
KW556_RS05445	COG3706	GGDEF domain
KW556_RS05450	COG0583	DNA-binding transcription factor activity
KW556_RS05470	COG5001	Diguanylate cyclase
KW556_RS05470	COG5002	protein histidine kinase activity
KW556_RS05470	COG3447	MASE1 domain protein
KW556_RS05480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KW556_RS05490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KW556_RS05500	COG0516	GMP reductase activity
KW556_RS05510	COG0642	Histidine kinase
KW556_RS05525	COG3385	transposase activity
KW556_RS05535	COG4221	oxidoreductase activity
KW556_RS05545	COG1022	Amp-dependent synthetase and ligase
KW556_RS05560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KW556_RS05575	COG3214	Protein conserved in bacteria
KW556_RS05585	COG2195	Cleaves the N-terminal amino acid of tripeptides
KW556_RS05590	COG0700	Nucleoside recognition
KW556_RS05595	COG3366	ferrous iron transmembrane transporter activity
KW556_RS05600	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KW556_RS05605	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KW556_RS05610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KW556_RS05615	COG1053	succinate dehydrogenase
KW556_RS05635	COG0584	glycerophosphoryl diester phosphodiesterase
KW556_RS05640	COG1511	domain protein
KW556_RS05640	COG3264	Mechanosensitive ion channel
KW556_RS05650	COG0739	heme binding
KW556_RS05660	COG0583	DNA-binding transcription factor activity
KW556_RS05675	COG3385	transposase activity
KW556_RS05685	COG0583	DNA-binding transcription factor activity
KW556_RS05690	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KW556_RS05720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KW556_RS05725	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KW556_RS05735	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KW556_RS05740	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KW556_RS05750	COG0180	Tryptophanyl-tRNA synthetase
KW556_RS05760	COG0512	Glutamine amidotransferase of anthranilate synthase
KW556_RS05765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KW556_RS05775	COG1012	belongs to the aldehyde dehydrogenase family
KW556_RS05790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KW556_RS05800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KW556_RS05800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KW556_RS05800	COG1013	pyruvate-flavodoxin oxidoreductase activity
KW556_RS05800	COG0674	pyruvate-flavodoxin oxidoreductase activity
KW556_RS05805	COG0366	Alpha amylase catalytic
KW556_RS05820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KW556_RS05825	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
KW556_RS05835	COG0490	domain, Protein
KW556_RS05835	COG0471	metal ion transport
KW556_RS05880	COG0012	GTP binding
KW556_RS05885	COG0193	aminoacyl-tRNA hydrolase activity
KW556_RS05890	COG0737	Belongs to the 5'-nucleotidase family
KW556_RS05895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KW556_RS05905	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KW556_RS05910	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KW556_RS05915	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KW556_RS05920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KW556_RS05925	COG2890	protein-(glutamine-N5) methyltransferase activity
KW556_RS05935	COG2912	Transglutaminase-like superfamily
KW556_RS05940	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KW556_RS05955	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KW556_RS05970	COG1881	PFAM PEBP family protein
KW556_RS05980	COG3385	transposase activity
KW556_RS06020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KW556_RS06035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KW556_RS06045	COG0583	DNA-binding transcription factor activity
KW556_RS06050	COG1028	Short-chain dehydrogenase reductase Sdr
KW556_RS06055	COG0616	signal peptide processing
KW556_RS06060	COG2211	Major facilitator Superfamily
KW556_RS06065	COG3706	GGDEF domain
KW556_RS06070	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KW556_RS06080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KW556_RS06085	COG0826	peptidase U32
KW556_RS06105	COG4251	negative regulation of phosphorylation
KW556_RS06115	COG4584	PFAM Integrase catalytic
KW556_RS06120	COG1484	DNA-dependent DNA replication
KW556_RS06170	COG3039	Transposase
KW556_RS06180	COG1309	transcriptional regulator
KW556_RS06195	COG1136	(ABC) transporter
KW556_RS06210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KW556_RS06255	COG5642	Protein of unknown function (DUF2384)
KW556_RS06260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KW556_RS06270	COG2194	sulfuric ester hydrolase activity
KW556_RS06310	COG3724	N-succinylarginine dihydrolase activity
KW556_RS06330	COG0840	transmembrane signaling receptor activity
KW556_RS06340	COG2971	BadF BadG BcrA BcrD
KW556_RS06350	COG4608	Belongs to the ABC transporter superfamily
KW556_RS06355	COG0444	Belongs to the ABC transporter superfamily
KW556_RS06360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KW556_RS06375	COG0784	Response regulator, receiver
KW556_RS06375	COG2205	protein histidine kinase activity
KW556_RS06405	COG3220	belongs to the UPF0276 family
KW556_RS06435	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KW556_RS06440	COG1289	transmembrane transporter activity
KW556_RS06445	COG0303	'Molybdopterin
KW556_RS06450	COG0746	molybdenum cofactor guanylyltransferase activity
KW556_RS06460	COG4662	Binding-protein-dependent transport system inner membrane component
KW556_RS06470	COG2204	response regulator
KW556_RS06475	COG3852	Histidine kinase
KW556_RS06485	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KW556_RS06550	COG3383	formate dehydrogenase (NAD+) activity
KW556_RS06550	COG3383	formate dehydrogenase (NAD+) activity
KW556_RS06555	COG0437	4 iron, 4 sulfur cluster binding
KW556_RS06575	COG0281	malic enzyme
KW556_RS06605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW556_RS06640	COG1737	Transcriptional regulator
KW556_RS06645	COG0469	pyruvate kinase activity
KW556_RS06660	COG1677	Flagellar hook-basal body complex protein FliE
KW556_RS06670	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KW556_RS06720	COG1987	bacterial-type flagellum assembly
KW556_RS06725	COG1684	flagellar biosynthetic protein fliR
KW556_RS06735	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KW556_RS06760	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KW556_RS06765	COG0784	Response regulator, receiver
KW556_RS06765	COG0643	Histidine kinase
KW556_RS06765	COG2198	Histidine kinase
KW556_RS06775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KW556_RS06780	COG1360	Flagellar Motor Protein
KW556_RS06785	COG1192	Involved in chromosome partitioning
KW556_RS06795	COG0835	chemotaxis
KW556_RS06810	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KW556_RS06815	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KW556_RS06820	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KW556_RS06825	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KW556_RS06830	COG1138	Cytochrome C-type biogenesis protein
KW556_RS06835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KW556_RS06840	COG3088	subunit of a heme lyase
KW556_RS06840	COG4235	cytochrome complex assembly
KW556_RS06850	COG2853	Lipoprotein
KW556_RS06860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KW556_RS06875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KW556_RS06885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KW556_RS06890	COG1882	Formate acetyltransferase
KW556_RS06900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KW556_RS06900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KW556_RS06905	COG0259	pyridoxamine-phosphate oxidase activity
KW556_RS06925	COG2850	peptidyl-arginine hydroxylation
KW556_RS06930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KW556_RS06935	COG2915	High frequency lysogenization protein hflD homolog
KW556_RS06940	COG0482	sulfurtransferase activity
KW556_RS06950	COG1187	pseudouridine synthase activity
KW556_RS06960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KW556_RS06965	COG2271	Major facilitator Superfamily
KW556_RS06970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KW556_RS06970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KW556_RS06970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW556_RS07040	COG4821	SIS domain
KW556_RS07055	COG1609	Transcriptional regulator
KW556_RS07060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KW556_RS07060	COG1263	PTS System
KW556_RS07065	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KW556_RS07070	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KW556_RS07075	COG1960	acyl-CoA dehydrogenase activity
KW556_RS07085	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KW556_RS07140	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KW556_RS07145	COG2867	negative regulation of translational initiation
KW556_RS07150	COG2914	Belongs to the UPF0125 (RnfH) family
KW556_RS07155	COG1473	amidohydrolase
KW556_RS07160	COG1960	acyl-CoA dehydrogenase activity
KW556_RS07165	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KW556_RS07170	COG0121	glutamine amidotransferase
KW556_RS07200	COG2197	response regulator
KW556_RS07205	COG3850	Histidine kinase
KW556_RS07210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KW556_RS07215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KW556_RS07225	COG0243	molybdopterin cofactor binding
KW556_RS07230	COG0437	4 iron, 4 sulfur cluster binding
KW556_RS07235	COG0348	domain, Protein
KW556_RS07245	COG3005	denitrification pathway
KW556_RS07250	COG0521	Mo-molybdopterin cofactor biosynthetic process
KW556_RS07255	COG0315	cyclic pyranopterin monophosphate synthase activity
KW556_RS07260	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KW556_RS07265	COG0314	molybdopterin synthase activity
KW556_RS07280	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KW556_RS07285	COG2267	carboxylic ester hydrolase activity
KW556_RS07300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KW556_RS07305	COG0303	'Molybdopterin
KW556_RS07310	COG0302	gtp cyclohydrolase
KW556_RS07315	COG0840	transmembrane signaling receptor activity
KW556_RS07320	COG0840	transmembrane signaling receptor activity
KW556_RS07325	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KW556_RS07335	COG0583	DNA-binding transcription factor activity
KW556_RS07340	COG2353	YceI-like domain
KW556_RS07380	COG1166	arginine decarboxylase activity
KW556_RS07400	COG0814	amino acid
KW556_RS07410	COG3681	Belongs to the UPF0597 family
KW556_RS07415	COG2964	Protein conserved in bacteria
KW556_RS07430	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KW556_RS07435	COG1288	antiporter activity
KW556_RS07440	COG0436	Aminotransferase
KW556_RS07450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KW556_RS07455	COG0739	heme binding
KW556_RS07455	COG0741	lytic transglycosylase activity
KW556_RS07455	COG1196	nuclear chromosome segregation
KW556_RS07470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KW556_RS07480	COG0788	formyltetrahydrofolate deformylase activity
KW556_RS07485	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KW556_RS07495	COG3118	belongs to the thioredoxin family
KW556_RS07505	COG0791	NLP P60 protein
KW556_RS07510	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KW556_RS07520	COG0471	metal ion transport
KW556_RS07550	COG1280	lysine exporter protein (LysE YggA)
KW556_RS07560	COG1012	belongs to the aldehyde dehydrogenase family
KW556_RS07560	COG1454	alcohol dehydrogenase
KW556_RS07565	COG2095	MarC family integral membrane protein
KW556_RS07575	COG0601	transmembrane transport
KW556_RS07580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KW556_RS07595	COG0861	Integral membrane protein TerC family
KW556_RS07600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KW556_RS07630	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KW556_RS07640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KW556_RS07645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KW556_RS07650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KW556_RS07655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KW556_RS07660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KW556_RS07675	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KW556_RS07680	COG0505	Belongs to the CarA family
KW556_RS07685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KW556_RS07715	COG3263	regulation of cellular component size
KW556_RS07725	COG1876	peptidase activity
KW556_RS07730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KW556_RS07735	COG1393	Belongs to the ArsC family
KW556_RS07745	COG3069	C4-dicarboxylate transmembrane transporter activity
KW556_RS07750	COG1473	amidohydrolase
KW556_RS07760	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KW556_RS07770	COG0017	Asparaginyl-tRNA synthetase
KW556_RS07785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KW556_RS07790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KW556_RS07795	COG0156	8-amino-7-oxononanoate synthase activity
KW556_RS07800	COG2226	methyltransferase
KW556_RS07800	COG1073	alpha beta
KW556_RS07805	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KW556_RS07810	COG0501	Belongs to the peptidase M48B family
KW556_RS07820	COG0633	Ferredoxin
KW556_RS07820	COG0633	Ferredoxin
KW556_RS07820	COG3217	Mosc domain protein beta barrel domain protein
KW556_RS07820	COG3217	Mosc domain protein beta barrel domain protein
KW556_RS07835	COG0674	pyruvate-flavodoxin oxidoreductase activity
KW556_RS07835	COG1013	pyruvate-flavodoxin oxidoreductase activity
KW556_RS07835	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KW556_RS07835	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KW556_RS07850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KW556_RS07855	COG1607	acyl-coa hydrolase
KW556_RS07865	COG3021	interspecies interaction between organisms
KW556_RS07870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KW556_RS07875	COG2027	D-alanyl-D-alanine carboxypeptidase
KW556_RS07880	COG1061	Type III restriction enzyme res subunit
KW556_RS07885	COG1566	PFAM secretion protein HlyD family protein
KW556_RS07895	COG1966	Carbon starvation protein
KW556_RS07900	COG3279	Response regulator of the LytR AlgR family
KW556_RS07905	COG3275	phosphorelay sensor kinase activity
KW556_RS07910	COG2199	diguanylate cyclase activity
KW556_RS07910	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KW556_RS07920	COG1846	Transcriptional regulator
KW556_RS07920	COG1940	carbohydrate kinase activity
KW556_RS07925	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KW556_RS07930	COG0363	glucosamine-6-phosphate deaminase activity
KW556_RS07935	COG1263	PTS System
KW556_RS07935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KW556_RS07935	COG2190	(PTS) system
KW556_RS07945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KW556_RS07950	COG0735	belongs to the Fur family
KW556_RS07960	COG0716	FMN binding
KW556_RS07975	COG0596	Alpha beta hydrolase
KW556_RS07980	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KW556_RS07985	COG0033	Phosphoglucomutase
KW556_RS07995	COG1846	Transcriptional regulator
KW556_RS08000	COG2951	lytic endotransglycosylase activity
KW556_RS08005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KW556_RS08010	COG4136	ATPase activity
KW556_RS08020	COG4134	Bacterial extracellular solute-binding protein
KW556_RS08030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KW556_RS08040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KW556_RS08050	COG0729	surface antigen
KW556_RS08055	COG2911	Protein conserved in bacteria
KW556_RS08075	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KW556_RS08085	COG0741	lytic transglycosylase activity
KW556_RS08095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KW556_RS08100	COG4771	TonB-dependent receptor
KW556_RS08105	COG1169	isochorismate synthase
KW556_RS08110	COG1021	2,3-dihydroxybenzoate-AMP ligase
KW556_RS08115	COG1535	isochorismatase
KW556_RS08115	COG3433	isochorismatase activity
KW556_RS08120	COG1028	Short-chain dehydrogenase reductase Sdr
KW556_RS08125	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KW556_RS08125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KW556_RS08150	COG1278	Cold shock
KW556_RS08175	COG4166	transmembrane transport
KW556_RS08180	COG1349	DNA-binding transcription factor activity
KW556_RS08185	COG1882	Formate acetyltransferase
KW556_RS08190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KW556_RS08195	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KW556_RS08205	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KW556_RS08210	COG1187	pseudouridine synthase activity
KW556_RS08220	COG4166	transmembrane transport
KW556_RS08225	COG0622	Phosphoesterase
KW556_RS08240	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KW556_RS08245	COG0784	Response regulator, receiver
KW556_RS08245	COG0835	chemotaxis
KW556_RS08250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KW556_RS08255	COG1815	bacterial-type flagellum-dependent cell motility
KW556_RS08275	COG4787	bacterial-type flagellum-dependent cell motility
KW556_RS08285	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KW556_RS08290	COG1706	bacterial-type flagellum-dependent cell motility
KW556_RS08305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KW556_RS08315	COG2239	Acts as a magnesium transporter
KW556_RS08325	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KW556_RS08330	COG2716	regulation of RNA biosynthetic process
KW556_RS08355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KW556_RS08360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KW556_RS08365	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KW556_RS08370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KW556_RS08390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KW556_RS08405	COG0590	tRNA wobble adenosine to inosine editing
KW556_RS08410	COG0573	inorganic phosphate transmembrane transporter activity
KW556_RS08415	COG0581	inorganic phosphate transmembrane transporter activity
KW556_RS08420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KW556_RS08425	COG0704	Plays a role in the regulation of phosphate uptake
KW556_RS08430	COG1253	flavin adenine dinucleotide binding
KW556_RS08445	COG0531	amino acid
KW556_RS08465	COG0287	Prephenate dehydrogenase
KW556_RS08465	COG1605	Chorismate mutase
KW556_RS08470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KW556_RS08480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KW556_RS08485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KW556_RS08520	COG0537	adenosine 5'-monophosphoramidase activity
KW556_RS08535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KW556_RS08550	COG1301	dicarboxylic acid transport
KW556_RS08565	COG2354	Protein conserved in bacteria
KW556_RS08575	COG2233	PERMEase
KW556_RS08580	COG3150	esterase
KW556_RS08585	COG1252	NADH dehydrogenase
KW556_RS08595	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KW556_RS08600	COG3300	MHYT domain
KW556_RS08600	COG5001	Diguanylate cyclase
KW556_RS08605	COG0446	pyridine nucleotide-disulphide oxidoreductase
KW556_RS08615	COG2373	Large extracellular alpha-helical protein
KW556_RS08620	COG4953	penicillin-binding protein 1C
KW556_RS08630	COG0582	viral genome integration into host DNA
KW556_RS08675	COG2974	May be involved in recombination
KW556_RS08705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KW556_RS08750	COG3646	Phage regulatory protein
KW556_RS08750	COG3645	SOS response
KW556_RS08945	COG3385	transposase activity
KW556_RS08965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KW556_RS08965	COG0301	tRNA thio-modification
KW556_RS09025	COG2089	acid synthase
KW556_RS09040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KW556_RS09050	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KW556_RS09065	COG1086	Polysaccharide biosynthesis protein
KW556_RS09080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KW556_RS09090	COG0483	inositol monophosphate 1-phosphatase activity
KW556_RS09100	COG0625	glutathione transferase activity
KW556_RS09105	COG2814	Major facilitator Superfamily
KW556_RS09110	COG0583	DNA-binding transcription factor activity
KW556_RS09115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KW556_RS09120	COG0243	molybdopterin cofactor binding
KW556_RS09140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KW556_RS09145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KW556_RS09155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KW556_RS09160	COG0509	glycine decarboxylation via glycine cleavage system
KW556_RS09165	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KW556_RS09165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KW556_RS09170	COG0840	transmembrane signaling receptor activity
KW556_RS09195	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KW556_RS09200	COG0574	Belongs to the PEP-utilizing enzyme family
KW556_RS09200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KW556_RS09220	COG3706	GGDEF domain
KW556_RS09245	COG1464	Belongs to the NlpA lipoprotein family
KW556_RS09250	COG3083	sulfuric ester hydrolase activity
KW556_RS09255	COG3082	Protein of unknown function (DUF1414)
KW556_RS09260	COG3081	Nucleoid-associated protein
KW556_RS09270	COG1175	transmembrane transport
KW556_RS09275	COG3833	ABC-type maltose transport systems, permease component
KW556_RS09280	COG3842	ATPase activity
KW556_RS09310	COG4783	chaperone-mediated protein folding
KW556_RS09320	COG1393	Belongs to the ArsC family
KW556_RS09330	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
KW556_RS09335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW556_RS09340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KW556_RS09345	COG2431	L-lysine efflux transmembrane transporter activity
KW556_RS09355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW556_RS09365	COG4160	amino acid transport
KW556_RS09370	COG0564	pseudouridine synthase activity
KW556_RS09385	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KW556_RS09395	COG0625	glutathione transferase activity
KW556_RS09425	COG1360	Flagellar Motor Protein
KW556_RS09430	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KW556_RS09445	COG3039	Transposase
KW556_RS09455	COG3437	response regulator, receiver
KW556_RS09510	COG4974	Belongs to the 'phage' integrase family
KW556_RS09530	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KW556_RS09540	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KW556_RS09545	COG0765	amino acid transport
KW556_RS09550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW556_RS09555	COG0765	amino acid transport
KW556_RS09560	COG1126	abc transporter atp-binding protein
KW556_RS09570	COG0724	RNA recognition motif
KW556_RS09575	COG4989	oxidoreductase activity
KW556_RS09600	COG3437	response regulator, receiver
KW556_RS09605	COG0583	DNA-binding transcription factor activity
KW556_RS09625	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KW556_RS09645	COG2814	Major facilitator Superfamily
KW556_RS09660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KW556_RS09665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KW556_RS09670	COG0539	negative regulation of cytoplasmic translation
KW556_RS09675	COG0776	regulation of translation
KW556_RS09685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KW556_RS09705	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KW556_RS09710	COG0602	queuosine metabolic process
KW556_RS09715	COG3530	Putative quorum-sensing-regulated virulence factor
KW556_RS09720	COG2096	Adenosyltransferase
KW556_RS09725	COG2916	Histone family protein nucleoid-structuring protein H-NS
KW556_RS09730	COG1757	Na H antiporter
KW556_RS09735	COG1435	thymidine kinase activity
KW556_RS09760	COG0392	lysyltransferase activity
KW556_RS09760	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KW556_RS09770	COG2205	protein histidine kinase activity
KW556_RS09775	COG0745	RESPONSE REGULATOR receiver
KW556_RS09795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KW556_RS09800	COG1278	Cold shock
KW556_RS09805	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KW556_RS09810	COG0542	response to heat
KW556_RS09815	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KW556_RS09820	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KW556_RS09825	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KW556_RS09830	COG3134	Outer membrane lipoprotein
KW556_RS09835	COG3706	GGDEF domain
KW556_RS09840	COG0492	ferredoxin-NADP+ reductase activity
KW556_RS09845	COG0686	Belongs to the AlaDH PNT family
KW556_RS09855	COG1674	ftsk spoiiie
KW556_RS09855	COG0531	amino acid
KW556_RS09860	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KW556_RS09865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KW556_RS09870	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KW556_RS09880	COG1286	toxin biosynthetic process
KW556_RS09885	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KW556_RS09895	COG0563	adenylate kinase activity
KW556_RS09900	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KW556_RS09910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KW556_RS09925	COG3300	MHYT domain
KW556_RS09925	COG5001	Diguanylate cyclase
KW556_RS09970	COG0659	secondary active sulfate transmembrane transporter activity
KW556_RS09980	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KW556_RS09985	COG0326	Molecular chaperone. Has ATPase activity
KW556_RS09990	COG4172	Belongs to the ABC transporter superfamily
KW556_RS09995	COG4172	Belongs to the ABC transporter superfamily
KW556_RS10005	COG4168	peptide transport system, permease
KW556_RS10015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KW556_RS10020	COG1842	Phage shock protein A
KW556_RS10035	COG3106	COG3106 Predicted ATPase
KW556_RS10040	COG3768	UPF0283 membrane protein
KW556_RS10045	COG0583	DNA-binding transcription factor activity
KW556_RS10050	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KW556_RS10055	COG3842	ATPase activity
KW556_RS10060	COG1176	ABC-type spermidine putrescine transport system, permease component I
KW556_RS10065	COG1177	transmembrane transport
KW556_RS10070	COG1012	belongs to the aldehyde dehydrogenase family
KW556_RS10095	COG2199	diguanylate cyclase activity
KW556_RS10100	COG2885	chlorophyll binding
KW556_RS10105	COG0861	Integral membrane protein TerC family
KW556_RS10130	COG3385	transposase activity
KW556_RS10140	COG2910	NAD(P)H-binding
KW556_RS10145	COG0583	DNA-binding transcription factor activity
KW556_RS10150	COG0583	DNA-binding transcription factor activity
KW556_RS10155	COG2271	Major facilitator Superfamily
KW556_RS10165	COG1335	isochorismatase
KW556_RS10180	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KW556_RS10190	COG0583	DNA-binding transcription factor activity
KW556_RS10195	COG2723	6-phospho-beta-galactosidase activity
KW556_RS10200	COG1944	ATP diphosphatase activity
KW556_RS10205	COG2116	formate transmembrane transporter activity
KW556_RS10210	COG1882	Formate acetyltransferase
KW556_RS10215	COG2983	Belongs to the UPF0260 family
KW556_RS10230	COG0058	SHG alpha-glucan phosphorylase activity
KW556_RS10240	COG3547	Transposase (IS116 IS110 IS902 family)
KW556_RS10295	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KW556_RS10300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KW556_RS10305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KW556_RS10320	COG0513	Belongs to the DEAD box helicase family
KW556_RS10325	COG0386	Belongs to the glutathione peroxidase family
KW556_RS10335	COG1181	Belongs to the D-alanine--D-alanine ligase family
KW556_RS10340	COG0383	alpha-mannosidase activity
KW556_RS10345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KW556_RS10345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KW556_RS10345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW556_RS10350	COG2188	Transcriptional regulator
KW556_RS10355	COG1570	exodeoxyribonuclease VII activity
KW556_RS10365	COG0516	GMP reductase activity
KW556_RS10365	COG0517	IMP dehydrogenase activity
KW556_RS10370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KW556_RS10370	COG0519	Catalyzes the synthesis of GMP from XMP
KW556_RS10405	COG0417	DNA replication proofreading
KW556_RS10420	COG1451	nucleotide metabolic process
KW556_RS10430	COG1025	Belongs to the peptidase M16 family
KW556_RS10435	COG2062	phosphohistidine phosphatase, SixA
KW556_RS10445	COG0697	spore germination
KW556_RS10465	COG3069	C4-dicarboxylate transmembrane transporter activity
KW556_RS10480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KW556_RS10480	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KW556_RS10485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KW556_RS10495	COG2985	domain, Protein
KW556_RS10495	COG0569	domain protein
KW556_RS10510	COG0556	nucleotide-excision repair
KW556_RS10520	COG0586	Pfam SNARE associated Golgi protein
KW556_RS10525	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KW556_RS10530	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KW556_RS10545	COG4681	YaeQ
KW556_RS10555	COG2932	Transcriptional regulator
KW556_RS10690	COG0640	Transcriptional regulator
KW556_RS10700	COG4373	Mu-like prophage FluMu protein gp28
KW556_RS10705	COG4383	Mu-like prophage protein gp29
KW556_RS10775	COG4397	Mu-like prophage major head subunit gpT
KW556_RS10780	COG4388	Caudovirus prohead serine protease
KW556_RS10860	COG3829	transcription factor binding
KW556_RS10895	COG0307	riboflavin synthase, alpha
KW556_RS10905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KW556_RS10910	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KW556_RS10915	COG0697	spore germination
KW556_RS10920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KW556_RS10965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KW556_RS10970	COG3099	Belongs to the UPF0263 family
KW556_RS10975	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KW556_RS10980	COG2894	cell division
KW556_RS10985	COG0850	regulation of cytokinetic process
KW556_RS10990	COG3100	YcgL domain-containing protein
KW556_RS10995	COG1760	l-serine dehydratase
KW556_RS11000	COG1760	l-serine dehydratase
KW556_RS11005	COG3123	guanosine phosphorylase activity
KW556_RS11015	COG0205	6-phosphofructokinase activity
KW556_RS11025	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KW556_RS11030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KW556_RS11040	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KW556_RS11045	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KW556_RS11050	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KW556_RS11065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KW556_RS11070	COG0517	IMP dehydrogenase activity
KW556_RS11070	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KW556_RS11070	COG0617	tRNA 3'-terminal CCA addition
KW556_RS11075	COG1643	Atp-dependent helicase
KW556_RS11085	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KW556_RS11100	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KW556_RS11105	COG2067	long-chain fatty acid transport protein
KW556_RS11110	COG2067	long-chain fatty acid transport protein
KW556_RS11120	COG1595	DNA-templated transcription, initiation
KW556_RS11130	COG2304	oxidoreductase activity
KW556_RS11150	COG0714	Associated with various cellular activities
KW556_RS11155	COG0183	Belongs to the thiolase family
KW556_RS11160	COG1250	3-hydroxyacyl-CoA dehydrogenase
KW556_RS11160	COG1024	Enoyl-CoA hydratase
KW556_RS11165	COG2719	SpoVR family
KW556_RS11170	COG2718	Belongs to the UPF0229 family
KW556_RS11175	COG2766	serine protein kinase
KW556_RS11180	COG0514	ATP-dependent DNA helicase (RecQ)
KW556_RS11185	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KW556_RS11190	COG0814	amino acid
KW556_RS11195	COG0494	nUDIX hydrolase
KW556_RS11215	COG2824	Alkylphosphonate utilization operon protein PhnA
KW556_RS11230	COG3791	Glutathione-dependent formaldehyde-activating
KW556_RS11235	COG0406	alpha-ribazole phosphatase activity
KW556_RS11240	COG3706	GGDEF domain
KW556_RS11245	COG2840	Smr protein MutS2
KW556_RS11250	COG2890	protein-(glutamine-N5) methyltransferase activity
KW556_RS11255	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KW556_RS11265	COG0513	Belongs to the DEAD box helicase family
KW556_RS11285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KW556_RS11285	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KW556_RS11290	COG0489	protein tyrosine kinase activity
KW556_RS11295	COG0572	uridine kinase
KW556_RS11300	COG0717	Belongs to the dCTP deaminase family
KW556_RS11305	COG0306	phosphate transporter
KW556_RS11325	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KW556_RS11330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KW556_RS11335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KW556_RS11345	COG0549	Belongs to the carbamate kinase family
KW556_RS11360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KW556_RS11365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KW556_RS11370	COG0697	spore germination
KW556_RS11380	COG3608	succinylglutamate desuccinylase aspartoacylase
KW556_RS11380	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KW556_RS11385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KW556_RS11390	COG2068	MobA-Related Protein
KW556_RS11395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KW556_RS11395	COG0493	'glutamate synthase
KW556_RS11400	COG0402	S-adenosylhomocysteine deaminase activity
KW556_RS11405	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KW556_RS11410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KW556_RS11410	COG2080	2 iron, 2 sulfur cluster binding
KW556_RS11415	COG2233	PERMEase
KW556_RS11420	COG0402	S-adenosylhomocysteine deaminase activity
KW556_RS11425	COG2252	PERMEase
KW556_RS11430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KW556_RS11435	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KW556_RS11440	COG2080	2 iron, 2 sulfur cluster binding
KW556_RS11445	COG3134	Outer membrane lipoprotein
KW556_RS11455	COG0318	PFAM AMP-dependent synthetase and ligase
KW556_RS11460	COG2199	diguanylate cyclase activity
KW556_RS11485	COG0107	imidazoleglycerol-phosphate synthase activity
KW556_RS11490	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KW556_RS11495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KW556_RS11500	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KW556_RS11500	COG0131	Imidazoleglycerol-phosphate dehydratase
KW556_RS11505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KW556_RS11510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KW556_RS11515	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KW556_RS11525	COG1199	ATP-dependent helicase activity
KW556_RS11530	COG1214	PFAM Peptidase M22, glycoprotease
KW556_RS11540	COG2267	carboxylic ester hydrolase activity
KW556_RS11545	COG0318	PFAM AMP-dependent synthetase and ligase
KW556_RS11555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KW556_RS11560	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KW556_RS11565	COG0709	Synthesizes selenophosphate from selenide and ATP
KW556_RS11580	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KW556_RS11585	COG0840	transmembrane signaling receptor activity
KW556_RS11590	COG1254	Belongs to the acylphosphatase family
KW556_RS11600	COG3385	transposase activity
KW556_RS11605	COG1530	ribonuclease E activity
KW556_RS11620	COG0424	maF-like protein
KW556_RS11625	COG1399	metal-binding, possibly nucleic acid-binding protein
KW556_RS11630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KW556_RS11635	COG0416	fatty acid biosynthetic process
KW556_RS11640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KW556_RS11650	COG1028	Short-chain dehydrogenase reductase Sdr
KW556_RS11655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KW556_RS11665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KW556_RS11670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KW556_RS11675	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KW556_RS11680	COG0470	DNA polymerase III
KW556_RS11685	COG0084	hydrolase, TatD family'
KW556_RS11710	COG0840	transmembrane signaling receptor activity
KW556_RS11720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KW556_RS11720	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KW556_RS11725	COG3008	intermembrane lipid transfer
KW556_RS11730	COG2995	paraquat-inducible protein a
KW556_RS11740	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KW556_RS11745	COG0372	Belongs to the citrate synthase family
KW556_RS11765	COG3385	transposase activity
KW556_RS11780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KW556_RS11785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KW556_RS11790	COG3046	protein related to deoxyribodipyrimidine photolyase
KW556_RS11800	COG3033	Beta-eliminating lyase
KW556_RS11805	COG0295	cytidine deaminase activity
KW556_RS11810	COG1346	cytolysis
KW556_RS11815	COG1380	Effector of murein hydrolase LrgA
KW556_RS11820	COG3345	alpha-galactosidase
KW556_RS11830	COG2925	Exonuclease
KW556_RS11835	COG2188	Transcriptional regulator
KW556_RS11845	COG1735	metal-dependent hydrolase with the TIM-barrel fold
KW556_RS11860	COG3457	Alanine racemase
KW556_RS11875	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KW556_RS11890	COG0814	amino acid
KW556_RS11895	COG1609	Transcriptional regulator
KW556_RS11900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW556_RS11900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW556_RS11905	COG1105	Belongs to the carbohydrate kinase PfkB family
KW556_RS11910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KW556_RS11910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KW556_RS11910	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KW556_RS11915	COG3313	Fe-S protein
KW556_RS11920	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KW556_RS11925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KW556_RS11930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KW556_RS11935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KW556_RS11945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KW556_RS11955	COG0366	Alpha amylase catalytic
KW556_RS11975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KW556_RS11980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KW556_RS11985	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KW556_RS11990	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KW556_RS11995	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KW556_RS12000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KW556_RS12000	COG0072	phenylalanine-tRNA ligase activity
KW556_RS12005	COG0776	regulation of translation
KW556_RS12035	COG3300	MHYT domain
KW556_RS12035	COG5001	Diguanylate cyclase
KW556_RS12040	COG1609	Transcriptional regulator
KW556_RS12045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KW556_RS12050	COG1879	ABC-type sugar transport system periplasmic component
KW556_RS12055	COG1172	Belongs to the binding-protein-dependent transport system permease family
KW556_RS12060	COG1129	ABC transporter
KW556_RS12065	COG1869	D-ribose catabolic process
KW556_RS12070	COG0625	glutathione transferase activity
KW556_RS12075	COG5654	RES domain protein
KW556_RS12090	COG1177	transmembrane transport
KW556_RS12115	COG0037	tRNA processing
KW556_RS12120	COG0589	response to stress
KW556_RS12125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KW556_RS12140	COG2217	Heavy metal translocating P-type atpase
KW556_RS12150	COG2010	Cytochrome c
KW556_RS12165	COG3278	Belongs to the heme-copper respiratory oxidase family
KW556_RS12175	COG1956	GAF domain-containing protein
KW556_RS12180	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KW556_RS12190	COG0308	aminopeptidase N
KW556_RS12200	COG2902	Dehydrogenase
KW556_RS12205	COG0167	dihydroorotate dehydrogenase activity
KW556_RS12220	COG0254	rRNA binding
KW556_RS12225	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KW556_RS12230	COG0116	Belongs to the methyltransferase superfamily
KW556_RS12230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KW556_RS12240	COG0488	(ABC) transporter
KW556_RS12250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KW556_RS12255	COG1067	ATP-dependent peptidase activity
KW556_RS12280	COG3141	response to X-ray
KW556_RS12285	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KW556_RS12320	COG3385	transposase activity
KW556_RS12330	COG1215	transferase activity, transferring glycosyl groups
KW556_RS12335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KW556_RS12375	COG2205	protein histidine kinase activity
KW556_RS12375	COG0784	Response regulator, receiver
KW556_RS12395	COG3385	transposase activity
KW556_RS12420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KW556_RS12470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KW556_RS12530	COG3267	Type II secretory pathway component ExeA
KW556_RS12530	COG3409	Peptidoglycan-binding domain 1 protein
KW556_RS12550	COG0730	response to heat
KW556_RS12560	COG1028	Short-chain dehydrogenase reductase Sdr
KW556_RS12570	COG1024	Enoyl-CoA hydratase
KW556_RS12575	COG1024	Enoyl-CoA hydratase
KW556_RS12580	COG1960	acyl-CoA dehydrogenase activity
KW556_RS12585	COG1960	acyl-CoA dehydrogenase activity
KW556_RS12590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KW556_RS12595	COG1024	Enoyl-CoA hydratase
KW556_RS12625	COG1584	GPR1 FUN34 yaaH family protein
KW556_RS12635	COG0456	acetyltransferase
KW556_RS12640	COG1115	amino acid carrier protein
KW556_RS12660	COG3039	Transposase
KW556_RS12680	COG1024	Enoyl-CoA hydratase
KW556_RS12695	COG3162	membrane
KW556_RS12700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KW556_RS12705	COG0488	(ABC) transporter
KW556_RS12710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KW556_RS12715	COG0776	regulation of translation
KW556_RS12720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KW556_RS12725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KW556_RS12730	COG0740	serine-type endopeptidase activity
KW556_RS12735	COG0544	peptidyl-prolyl cis-trans isomerase activity
KW556_RS12745	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KW556_RS12750	COG4591	ABC-type transport system involved in lipoprotein release permease component
KW556_RS12755	COG1136	(ABC) transporter
KW556_RS12760	COG4591	ABC-type transport system involved in lipoprotein release permease component
KW556_RS12770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KW556_RS12775	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KW556_RS12780	COG4166	transmembrane transport
KW556_RS12795	COG1560	Kdo2-lipid A biosynthetic process
KW556_RS12800	COG1560	Kdo2-lipid A biosynthetic process
KW556_RS12815	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KW556_RS12820	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KW556_RS12830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KW556_RS12835	COG2832	Protein of unknown function (DUF454)
KW556_RS12840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KW556_RS12855	COG1011	Hydrolase
KW556_RS12860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KW556_RS12895	COG3593	DNA synthesis involved in DNA repair
KW556_RS12910	COG0583	DNA-binding transcription factor activity
KW556_RS12915	COG0730	response to heat
KW556_RS12920	COG3148	PFAM DTW domain containing protein
KW556_RS12925	COG1940	carbohydrate kinase activity
KW556_RS12925	COG1846	Transcriptional regulator
KW556_RS12930	COG0840	transmembrane signaling receptor activity
KW556_RS12935	COG3012	SEC-C Motif Domain Protein
KW556_RS12940	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KW556_RS12945	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KW556_RS12950	COG0247	lactate metabolic process
KW556_RS12965	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
KW556_RS12970	COG0437	4 iron, 4 sulfur cluster binding
KW556_RS12975	COG3301	Polysulphide reductase, NrfD
KW556_RS12980	COG1138	Cytochrome C-type biogenesis protein
KW556_RS12990	COG3088	subunit of a heme lyase
KW556_RS12990	COG4235	cytochrome complex assembly
KW556_RS13010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KW556_RS13015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KW556_RS13020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KW556_RS13030	COG1840	ABC-type Fe3 transport system, periplasmic component
KW556_RS13035	COG3842	ATPase activity
KW556_RS13045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KW556_RS13060	COG0045	succinate-CoA ligase (ADP-forming) activity
KW556_RS13065	COG0508	dehydrogenase complex catalyzes the overall conversion of
KW556_RS13070	COG0567	Dehydrogenase, E1 component
KW556_RS13080	COG1053	succinate dehydrogenase
KW556_RS13085	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KW556_RS13110	COG0456	acetyltransferase
KW556_RS13140	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KW556_RS13155	COG2501	S4 domain
KW556_RS13165	COG1132	(ABC) transporter
KW556_RS13170	COG1132	(ABC) transporter
KW556_RS13180	COG3118	belongs to the thioredoxin family
KW556_RS13185	COG0471	metal ion transport
KW556_RS13205	COG0672	)-iron permease
KW556_RS13235	COG2814	Major facilitator Superfamily
KW556_RS13250	COG1136	(ABC) transporter
KW556_RS13255	COG0577	efflux transmembrane transporter activity
KW556_RS13275	COG0596	Alpha beta hydrolase
KW556_RS13295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KW556_RS13300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KW556_RS13300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KW556_RS13305	COG0527	aspartate kinase activity
KW556_RS13315	COG1368	sulfuric ester hydrolase activity
KW556_RS13320	COG1619	proteins homologs of microcin C7 resistance protein MccF
KW556_RS13325	COG4667	esterase of the alpha-beta hydrolase superfamily
KW556_RS13345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KW556_RS13345	COG1648	precorrin-2 dehydrogenase activity
KW556_RS13355	COG0393	Putative heavy-metal-binding
KW556_RS13360	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KW556_RS13365	COG0285	dihydrofolate synthase activity
KW556_RS13370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KW556_RS13375	COG0101	tRNA pseudouridine synthase activity
KW556_RS13385	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KW556_RS13390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KW556_RS13395	COG0671	phosphoesterase, PA-phosphatase related
KW556_RS13400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KW556_RS13405	COG2056	Na+-H+ antiporter family
KW556_RS13410	COG3300	MHYT domain
KW556_RS13410	COG5001	Diguanylate cyclase
KW556_RS13425	COG2050	protein possibly involved in aromatic compounds catabolism
KW556_RS13435	COG0277	FAD linked oxidase domain protein
KW556_RS13435	COG0247	lactate metabolic process
KW556_RS13445	COG1253	flavin adenine dinucleotide binding
KW556_RS13450	COG1902	pentaerythritol trinitrate reductase activity
KW556_RS13465	COG0647	UMP catabolic process
KW556_RS13470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KW556_RS13470	COG4651	solute:proton antiporter activity
KW556_RS13480	COG0367	asparagine synthase
KW556_RS13495	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KW556_RS13500	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KW556_RS13505	COG0649	NAD binding
KW556_RS13505	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KW556_RS13520	COG1034	ATP synthesis coupled electron transport
KW556_RS13525	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KW556_RS13530	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KW556_RS13535	COG0839	Belongs to the complex I subunit 6 family
KW556_RS13540	COG0713	ATP synthesis coupled electron transport
KW556_RS13550	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KW556_RS13555	COG1007	ATP synthesis coupled electron transport
KW556_RS13570	COG2199	diguanylate cyclase activity
KW556_RS13570	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KW556_RS13575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KW556_RS13575	COG0047	phosphoribosylformylglycinamidine synthase activity
KW556_RS13580	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KW556_RS13585	COG1645	bacterial-type flagellum-dependent swarming motility
KW556_RS13590	COG1160	GTP binding
KW556_RS13595	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KW556_RS13600	COG2976	Protein conserved in bacteria
KW556_RS13605	COG0124	histidyl-tRNA synthetase
KW556_RS13610	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KW556_RS13625	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KW556_RS13630	COG0105	UTP biosynthetic process
KW556_RS13645	COG3385	transposase activity
KW556_RS13650	COG0633	Ferredoxin
KW556_RS13655	COG0443	Heat shock 70 kDa protein
KW556_RS13660	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KW556_RS13670	COG0822	iron-sulfur transferase activity
KW556_RS13675	COG1104	cysteine desulfurase activity
KW556_RS13695	COG3154	lipid carrier protein
KW556_RS13700	COG0826	peptidase U32
KW556_RS13705	COG0826	peptidase U32
KW556_RS13720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KW556_RS13725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KW556_RS13730	COG1862	Preprotein translocase
KW556_RS13735	COG0343	queuine tRNA-ribosyltransferase activity
KW556_RS13740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KW556_RS13745	COG0517	IMP dehydrogenase activity
KW556_RS13755	COG3634	alkyl hydroperoxide reductase activity
KW556_RS13785	COG3385	transposase activity
KW556_RS13820	COG1242	4 iron, 4 sulfur cluster binding
KW556_RS13825	COG0069	glutamate synthase activity
KW556_RS13825	COG0067	glutamate synthase
KW556_RS13825	COG0070	glutamate synthase
KW556_RS13830	COG0493	'glutamate synthase
KW556_RS13840	COG0513	Belongs to the DEAD box helicase family
KW556_RS13865	COG0023	Translation Initiation Factor
KW556_RS13870	COG2119	membrane
KW556_RS13920	COG0215	cysteine-tRNA ligase activity
KW556_RS13925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KW556_RS13935	COG3385	transposase activity
KW556_RS13940	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KW556_RS13950	COG3039	Transposase
KW556_RS14005	COG0322	excinuclease ABC activity
KW556_RS14010	COG2197	response regulator
KW556_RS14015	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KW556_RS14020	COG2835	tetraacyldisaccharide 4'-kinase activity
KW556_RS14025	COG1663	tetraacyldisaccharide 4'-kinase activity
KW556_RS14035	COG0658	competence protein
KW556_RS14035	COG2333	competence protein COMEC
KW556_RS14050	COG1448	Aminotransferase
KW556_RS14060	COG0583	DNA-binding transcription factor activity
KW556_RS14065	COG3085	chromosome segregation
KW556_RS14070	COG4574	serine-type endopeptidase inhibitor activity
KW556_RS14075	COG0584	glycerophosphoryl diester phosphodiesterase
KW556_RS14085	COG1349	DNA-binding transcription factor activity
KW556_RS14090	COG2271	Major facilitator Superfamily
KW556_RS14095	COG3385	transposase activity
KW556_RS14100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KW556_RS14105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KW556_RS14110	COG0840	transmembrane signaling receptor activity
KW556_RS14120	COG0583	DNA-binding transcription factor activity
KW556_RS14140	COG0656	L-ascorbic acid biosynthetic process
KW556_RS14150	COG2814	Major facilitator Superfamily
KW556_RS14155	COG2249	NAD(P)H dehydrogenase (quinone) activity
KW556_RS14170	COG3220	belongs to the UPF0276 family
KW556_RS14190	COG1294	oxidase, subunit
KW556_RS14200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KW556_RS14210	COG2979	Protein of unknown function (DUF533)
KW556_RS14225	COG0583	DNA-binding transcription factor activity
KW556_RS14235	COG2807	transmembrane transport
KW556_RS14240	COG1187	pseudouridine synthase activity
KW556_RS14285	COG4657	Part of a membrane complex involved in electron transport
KW556_RS14290	COG2878	Part of a membrane complex involved in electron transport
KW556_RS14300	COG4658	electron transport chain
KW556_RS14305	COG4659	FMN binding
KW556_RS14310	COG4660	Part of a membrane complex involved in electron transport
KW556_RS14315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KW556_RS14320	COG0346	lactoylglutathione lyase activity
KW556_RS14355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KW556_RS14360	COG1199	ATP-dependent helicase activity
KW556_RS14370	COG0123	including yeast histone deacetylase and acetoin utilization protein
KW556_RS14375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KW556_RS14380	COG1785	Belongs to the alkaline phosphatase family
KW556_RS14400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KW556_RS14405	COG2197	response regulator
KW556_RS14415	COG2271	Major facilitator Superfamily
KW556_RS14420	COG3706	GGDEF domain
KW556_RS14425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW556_RS14430	COG0765	amino acid transport
KW556_RS14445	COG1126	abc transporter atp-binding protein
KW556_RS14450	COG0217	transcriptional regulatory protein
KW556_RS14455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KW556_RS14465	COG1801	Protein of unknown function DUF72
KW556_RS14470	COG4106	trans-aconitate 2-methyltransferase activity
KW556_RS14475	COG0500	methyltransferase
KW556_RS14495	COG0450	alkyl hydroperoxide reductase
KW556_RS14500	COG0583	DNA-binding transcription factor activity
KW556_RS14505	COG0791	NLP P60 protein
KW556_RS14515	COG0583	DNA-binding transcription factor activity
KW556_RS14520	COG2610	gluconate transmembrane transporter activity
KW556_RS14525	COG3048	D-serine ammonia-lyase activity
KW556_RS14535	COG0538	isocitrate dehydrogenase activity
KW556_RS14540	COG2207	Transcriptional regulator
KW556_RS14550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KW556_RS14565	COG3152	Membrane
KW556_RS14600	COG1309	transcriptional regulator
KW556_RS14630	COG0534	Mate efflux family protein
KW556_RS14640	COG2841	Protein conserved in bacteria
KW556_RS14650	COG3300	MHYT domain
KW556_RS14650	COG5001	Diguanylate cyclase
KW556_RS14655	COG3132	Protein of unknown function, DUF480
KW556_RS14685	COG0708	Exodeoxyribonuclease III
KW556_RS14710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW556_RS14715	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KW556_RS14725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KW556_RS14730	COG1120	ATPase activity
KW556_RS14735	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KW556_RS14740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KW556_RS14745	COG2375	cellular response to nickel ion
KW556_RS14750	COG0784	Response regulator, receiver
KW556_RS14750	COG3437	response regulator, receiver
KW556_RS14760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KW556_RS14765	COG0328	RNA-DNA hybrid ribonuclease activity
KW556_RS14770	COG2226	methyltransferase
KW556_RS14775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KW556_RS14780	COG0741	lytic transglycosylase activity
KW556_RS14780	COG1388	LysM domain
KW556_RS14805	COG5000	phosphorelay sensor kinase activity
KW556_RS14805	COG5002	protein histidine kinase activity
KW556_RS14810	COG0745	RESPONSE REGULATOR receiver
KW556_RS14815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW556_RS14820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KW556_RS14825	COG0582	viral genome integration into host DNA
KW556_RS14850	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
KW556_RS14860	COG5377	YqaJ viral recombinase family
KW556_RS14905	COG2003	Belongs to the UPF0758 family
KW556_RS14965	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KW556_RS14975	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KW556_RS14980	COG3039	Transposase
KW556_RS15010	COG1388	LysM domain
KW556_RS15010	COG1376	ErfK ybiS ycfS ynhG family protein
KW556_RS15035	COG0564	pseudouridine synthase activity
KW556_RS15045	COG1454	alcohol dehydrogenase
KW556_RS15050	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KW556_RS15055	COG0702	epimerase
KW556_RS15065	COG0095	Lipoate-protein ligase
KW556_RS15075	COG0577	efflux transmembrane transporter activity
KW556_RS15075	COG1136	(ABC) transporter
KW556_RS15080	COG1136	(ABC) transporter
KW556_RS15080	COG0577	efflux transmembrane transporter activity
KW556_RS15085	COG1136	(ABC) transporter
KW556_RS15085	COG0577	efflux transmembrane transporter activity
KW556_RS15090	COG1566	PFAM secretion protein HlyD family protein
KW556_RS15125	COG0446	pyridine nucleotide-disulphide oxidoreductase
KW556_RS15135	COG1285	pathogenesis
KW556_RS15175	COG1349	DNA-binding transcription factor activity
KW556_RS15185	COG1028	Short-chain dehydrogenase reductase Sdr
KW556_RS15255	COG0484	heat shock protein binding
KW556_RS15260	COG0443	Heat shock 70 kDa protein
KW556_RS15265	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KW556_RS15270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KW556_RS15275	COG0497	DNA recombination
KW556_RS15280	COG1227	inorganic diphosphatase activity
KW556_RS15285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW556_RS15290	COG0577	efflux transmembrane transporter activity
KW556_RS15290	COG1136	(ABC) transporter
KW556_RS15350	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KW556_RS15355	COG1091	dTDP-4-dehydrorhamnose reductase activity
KW556_RS15370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KW556_RS15425	COG1083	cytidylyl-transferase
KW556_RS15440	COG2089	acid synthase
KW556_RS15445	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KW556_RS15450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KW556_RS15460	COG2244	polysaccharide biosynthetic process
KW556_RS15475	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KW556_RS15490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KW556_RS15495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW556_RS15500	COG1309	transcriptional regulator
KW556_RS15515	COG1342	Belongs to the UPF0251 family
KW556_RS15535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KW556_RS15550	COG1943	Transposase
KW556_RS15580	COG4584	PFAM Integrase catalytic
KW556_RS15585	COG1484	DNA-dependent DNA replication
KW556_RS15600	COG3344	reverse transcriptase
KW556_RS15645	COG3173	Aminoglycoside phosphotransferase
KW556_RS15650	COG0488	(ABC) transporter
KW556_RS15685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KW556_RS15690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW556_RS15740	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KW556_RS15790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KW556_RS15795	COG0083	homoserine kinase activity
KW556_RS15805	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KW556_RS15810	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KW556_RS15815	COG1946	Acyl-CoA thioesterase
KW556_RS15830	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KW556_RS15840	COG0009	L-threonylcarbamoyladenylate synthase
KW556_RS15850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KW556_RS15855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KW556_RS15855	COG0512	Glutamine amidotransferase of anthranilate synthase
KW556_RS15860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KW556_RS15865	COG0134	indole-3-glycerol-phosphate synthase activity
KW556_RS15865	COG0135	phosphoribosylanthranilate isomerase activity
KW556_RS15870	COG0133	tryptophan synthase activity
KW556_RS15875	COG0159	tryptophan synthase activity
KW556_RS15895	COG3385	transposase activity
KW556_RS15905	COG1988	membrane-bound metal-dependent
KW556_RS15925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KW556_RS15935	COG0798	PFAM Bile acid sodium symporter
KW556_RS15965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KW556_RS15975	COG0745	RESPONSE REGULATOR receiver
KW556_RS15990	COG4988	ABC transporter
KW556_RS15995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KW556_RS16015	COG1720	tRNA m6t6A37 methyltransferase activity
KW556_RS16020	COG3038	cytochrome b561
KW556_RS16040	COG2862	Uncharacterized protein family, UPF0114
KW556_RS16055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KW556_RS16060	COG1396	sequence-specific DNA binding
KW556_RS16060	COG1917	Cupin 2, conserved barrel domain protein
KW556_RS16075	COG0531	amino acid
KW556_RS16085	COG0531	amino acid
KW556_RS16090	COG1283	sodium-dependent phosphate transmembrane transporter activity
KW556_RS16095	COG0545	Peptidyl-prolyl cis-trans isomerase
KW556_RS16100	COG0405	Gamma-glutamyltransferase
KW556_RS16105	COG2974	May be involved in recombination
KW556_RS16115	COG0420	3'-5' exonuclease activity
KW556_RS16120	COG0419	ATPase involved in DNA repair
KW556_RS16125	COG3384	dioxygenase
KW556_RS16135	COG0469	pyruvate kinase activity
KW556_RS16140	COG1196	nuclear chromosome segregation
KW556_RS16140	COG3264	Mechanosensitive ion channel
KW556_RS16150	COG3590	peptidase
KW556_RS16155	COG3706	GGDEF domain
KW556_RS16160	COG2190	(PTS) system
KW556_RS16170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW556_RS16175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KW556_RS16180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KW556_RS16205	COG2770	Histidine kinase
KW556_RS16205	COG3437	response regulator, receiver
KW556_RS16210	COG3267	Type II secretory pathway component ExeA
KW556_RS16210	COG3409	Peptidoglycan-binding domain 1 protein
KW556_RS16225	COG1450	Type ii and iii secretion system protein
KW556_RS16230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KW556_RS16235	COG1459	type II secretion system
KW556_RS16240	COG2165	general secretion pathway protein
KW556_RS16250	COG2165	general secretion pathway protein
KW556_RS16260	COG3156	type II secretion system protein K
KW556_RS16270	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KW556_RS16280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KW556_RS16285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KW556_RS16295	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KW556_RS16300	COG2723	6-phospho-beta-galactosidase activity
KW556_RS16305	COG1447	Phosphotransferase system cellobiose-specific component IIA
KW556_RS16310	COG2169	Transcriptional regulator
KW556_RS16310	COG1917	Cupin 2, conserved barrel domain protein
KW556_RS16315	COG1486	melibiose metabolic process
KW556_RS16325	COG0582	viral genome integration into host DNA
KW556_RS16335	COG3311	Transcriptional regulator
KW556_RS16355	COG5377	YqaJ viral recombinase family
KW556_RS16400	COG2003	Belongs to the UPF0758 family
KW556_RS16455	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KW556_RS16470	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KW556_RS16485	COG0670	Belongs to the BI1 family
KW556_RS16490	COG1289	transmembrane transporter activity
KW556_RS16495	COG2920	part of a sulfur-relay system
KW556_RS16500	COG0673	inositol 2-dehydrogenase activity
KW556_RS16505	COG0583	DNA-binding transcription factor activity
KW556_RS16560	COG1032	radical SAM domain protein
KW556_RS16570	COG1566	PFAM secretion protein HlyD family protein
KW556_RS16575	COG3706	GGDEF domain
KW556_RS16580	COG1752	Esterase of the alpha-beta hydrolase superfamily
KW556_RS16585	COG0531	amino acid
KW556_RS16615	COG0281	malic enzyme
KW556_RS16625	COG0534	Mate efflux family protein
KW556_RS16640	COG2233	PERMEase
KW556_RS16645	COG0095	Lipoate-protein ligase
KW556_RS16650	COG1115	amino acid carrier protein
KW556_RS16655	COG0019	diaminopimelate decarboxylase activity
KW556_RS16665	COG0678	peroxiredoxin activity
KW556_RS16690	COG0545	Peptidyl-prolyl cis-trans isomerase
KW556_RS16695	COG3142	Participates in the control of copper homeostasis
KW556_RS16700	COG1940	carbohydrate kinase activity
KW556_RS16720	COG5002	protein histidine kinase activity
KW556_RS16725	COG0745	RESPONSE REGULATOR receiver
KW556_RS16730	COG0346	lactoylglutathione lyase activity
KW556_RS16735	COG3284	Transcriptional regulator
KW556_RS16750	COG0697	spore germination
KW556_RS16760	COG3290	protein histidine kinase activity
KW556_RS16765	COG0281	malic enzyme
KW556_RS16780	COG1846	Transcriptional regulator
KW556_RS16815	COG0602	queuosine metabolic process
KW556_RS16820	COG1328	CTP reductase activity
KW556_RS16830	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KW556_RS16835	COG3115	cell septum assembly
KW556_RS16840	COG1196	nuclear chromosome segregation
KW556_RS16850	COG2860	membrane
KW556_RS16860	COG3108	Peptidase M15
KW556_RS16865	COG2989	Protein conserved in bacteria
KW556_RS16880	COG0463	Glycosyl transferase, family 2
KW556_RS16895	COG0366	Alpha amylase catalytic
KW556_RS16930	COG2199	diguanylate cyclase activity
KW556_RS16930	COG2203	Gaf domain
KW556_RS16940	COG3590	peptidase
KW556_RS16950	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KW556_RS16955	COG1982	Orn Lys Arg decarboxylase major
KW556_RS16960	COG0531	amino acid
KW556_RS16965	COG3710	Transcriptional regulator
KW556_RS16970	COG0531	amino acid
KW556_RS17000	COG0814	amino acid
KW556_RS17030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KW556_RS17035	COG0739	heme binding
KW556_RS17040	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KW556_RS17060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KW556_RS17075	COG3091	SprT-like family
KW556_RS17085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KW556_RS17090	COG0189	ligase activity
KW556_RS17095	COG1678	Uncharacterized ACR, COG1678
KW556_RS17100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KW556_RS17105	COG3104	oligopeptide transport
KW556_RS17120	COG0714	Associated with various cellular activities
KW556_RS17135	COG1115	amino acid carrier protein
KW556_RS17140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KW556_RS17150	COG0825	malonyl-CoA metabolic process
KW556_RS17160	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KW556_RS17165	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KW556_RS17170	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KW556_RS17175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KW556_RS17180	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KW556_RS17195	COG0750	zinc metalloprotease
KW556_RS17200	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KW556_RS17205	COG0575	Belongs to the CDS family
KW556_RS17210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KW556_RS17215	COG0233	cytoplasmic translational termination
KW556_RS17220	COG0528	UMP kinase activity
KW556_RS17225	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KW556_RS17230	COG0052	Belongs to the universal ribosomal protein uS2 family
KW556_RS17235	COG0024	Methionine aminopeptidase
KW556_RS17240	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KW556_RS17245	COG2171	N-acyltransferase activity
KW556_RS17255	COG1263	PTS System
KW556_RS17255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KW556_RS17275	COG0564	pseudouridine synthase activity
KW556_RS17280	COG3098	single-species biofilm formation
KW556_RS17305	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KW556_RS17315	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KW556_RS17315	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KW556_RS17330	COG1611	Belongs to the LOG family
KW556_RS17335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KW556_RS17340	COG0473	3-isopropylmalate dehydrogenase activity
KW556_RS17350	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KW556_RS17355	COG2363	Small membrane protein
KW556_RS17365	COG0583	DNA-binding transcription factor activity
KW556_RS17370	COG0840	transmembrane signaling receptor activity
KW556_RS17375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KW556_RS17390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KW556_RS17395	COG1666	GTP binding
KW556_RS17400	COG3248	Nucleoside-binding outer membrane protein
KW556_RS17405	COG2211	Major facilitator Superfamily
KW556_RS17410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KW556_RS17420	COG2813	Specifically methylates the guanine in position
KW556_RS17425	COG0271	Belongs to the BolA IbaG family
KW556_RS17430	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KW556_RS17435	COG1805	sodium ion transport
KW556_RS17440	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KW556_RS17445	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KW556_RS17450	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KW556_RS17455	COG2871	sodium ion transport
KW556_RS17460	COG1477	protein flavinylation
KW556_RS17490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KW556_RS17505	COG0300	oxidoreductase activity
KW556_RS17515	COG0415	Belongs to the DNA photolyase family
KW556_RS17520	COG0789	Transcriptional regulator
KW556_RS17525	COG3272	Protein of unknown function (DUF1722)
KW556_RS17555	COG1605	Chorismate mutase
KW556_RS17555	COG0077	Prephenate dehydratase
KW556_RS17585	COG5377	YqaJ viral recombinase family
KW556_RS17680	COG0583	DNA-binding transcription factor activity
KW556_RS17720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KW556_RS17740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KW556_RS17750	COG3093	addiction module antidote protein HigA
KW556_RS17790	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KW556_RS17845	COG4584	PFAM Integrase catalytic
KW556_RS17850	COG1484	DNA-dependent DNA replication
KW556_RS17880	COG3550	peptidyl-serine autophosphorylation
KW556_RS17930	COG0514	ATP-dependent DNA helicase (RecQ)
KW556_RS17935	COG0514	ATP-dependent DNA helicase (RecQ)
KW556_RS17955	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KW556_RS17960	COG3385	transposase activity
KW556_RS18040	COG1357	PFAM Pentapeptide repeats (8 copies)
KW556_RS18065	COG4644	lycopene metabolic process
KW556_RS18090	COG4133	protoheme IX ABC transporter activity
KW556_RS18115	COG2003	Belongs to the UPF0758 family
KW556_RS18165	COG3173	Aminoglycoside phosphotransferase
KW556_RS18190	COG1695	Transcriptional regulator
KW556_RS18200	COG3385	transposase activity
KW556_RS18270	COG0300	oxidoreductase activity
KW556_RS18295	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KW556_RS18335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KW556_RS18340	COG0826	peptidase U32
KW556_RS18345	COG1280	lysine exporter protein (LysE YggA)
KW556_RS18355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KW556_RS18365	COG0745	RESPONSE REGULATOR receiver
KW556_RS18370	COG3385	transposase activity
KW556_RS18380	COG0643	Histidine kinase
KW556_RS18380	COG2198	Histidine kinase
KW556_RS18390	COG0835	chemotaxis
KW556_RS18395	COG0840	transmembrane signaling receptor activity
KW556_RS18405	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KW556_RS18410	COG2201	protein-glutamate methylesterase activity
KW556_RS18420	COG2814	Major facilitator Superfamily
KW556_RS18425	COG4771	TonB-dependent receptor
KW556_RS18445	COG0748	coenzyme F420 binding
KW556_RS18450	COG3721	Heme iron utilization protein
KW556_RS18460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KW556_RS18475	COG3275	phosphorelay sensor kinase activity
KW556_RS18480	COG3279	Response regulator of the LytR AlgR family
KW556_RS18485	COG1966	Carbon starvation protein
KW556_RS18490	COG3340	Belongs to the peptidase S51 family
KW556_RS18500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KW556_RS18515	COG0737	Belongs to the 5'-nucleotidase family
KW556_RS18535	COG2204	response regulator
KW556_RS18540	COG0545	Peptidyl-prolyl cis-trans isomerase
KW556_RS18550	COG2900	Belongs to the SlyX family
KW556_RS18555	COG1047	Peptidyl-prolyl cis-trans
KW556_RS18560	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KW556_RS18570	COG0835	chemotaxis
KW556_RS18570	COG0784	Response regulator, receiver
KW556_RS18575	COG0429	hydrolase of the alpha beta-hydrolase fold
KW556_RS18580	COG5001	Diguanylate cyclase
KW556_RS18580	COG4251	negative regulation of phosphorylation
KW556_RS18580	COG3706	GGDEF domain
KW556_RS18580	COG2203	Gaf domain
KW556_RS18585	COG3089	Belongs to the UPF0270 family
KW556_RS18590	COG3954	Phosphoribulokinase
KW556_RS18605	COG1765	OsmC-like protein
KW556_RS18645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KW556_RS18650	COG2313	pseudouridylate synthase activity
KW556_RS18680	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
KW556_RS18700	COG0569	domain protein
KW556_RS18700	COG2985	domain, Protein
KW556_RS18705	COG1272	protein, Hemolysin III
KW556_RS18710	COG0076	glutamate decarboxylase activity
KW556_RS18715	COG2917	probably involved in intracellular septation
KW556_RS18720	COG2350	Protein conserved in bacteria
KW556_RS18730	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KW556_RS18735	COG1381	Involved in DNA repair and RecF pathway recombination
KW556_RS18750	COG0681	Belongs to the peptidase S26 family
KW556_RS18755	COG0481	GTPase activity
KW556_RS18765	COG3026	antisigma factor binding
KW556_RS18770	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
KW556_RS18775	COG1595	DNA-templated transcription, initiation
KW556_RS18780	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KW556_RS18790	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KW556_RS18795	COG0354	folic acid binding
KW556_RS18840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KW556_RS18845	COG0191	fructose-bisphosphate aldolase activity
KW556_RS18850	COG0126	phosphoglycerate kinase activity
KW556_RS18855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KW556_RS18860	COG1940	carbohydrate kinase activity
KW556_RS18865	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KW556_RS18870	COG2816	NAD+ diphosphatase activity
KW556_RS18880	COG4991	sh3 domain protein
KW556_RS18885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KW556_RS18895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KW556_RS18900	COG0840	transmembrane signaling receptor activity
KW556_RS18910	COG1278	Cold shock
KW556_RS18950	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KW556_RS18955	COG1162	GTPase activity
KW556_RS18960	COG0688	phosphatidylethanolamine metabolic process
KW556_RS18965	COG4628	conserved protein (DUF2132)
KW556_RS18980	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KW556_RS18995	COG1073	alpha beta
KW556_RS19000	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KW556_RS19005	COG2195	Cleaves the N-terminal amino acid of tripeptides
KW556_RS19010	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KW556_RS19015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KW556_RS19020	COG3178	'Phosphotransferase
KW556_RS19025	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KW556_RS19030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KW556_RS19035	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KW556_RS19040	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KW556_RS19045	COG2967	ApaG domain
KW556_RS19050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KW556_RS19065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KW556_RS19080	COG3314	Sporulation integral membrane protein YlbJ
KW556_RS19085	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KW556_RS19090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KW556_RS19095	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KW556_RS19100	COG0142	geranyltranstransferase activity
KW556_RS19105	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KW556_RS19110	COG0330	HflC and HflK could
KW556_RS19115	COG0330	HflC and HflK could
KW556_RS19120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KW556_RS19125	COG1923	regulation of RNA biosynthetic process
KW556_RS19130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KW556_RS19135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KW556_RS19145	COG0802	atpase or kinase
KW556_RS19150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KW556_RS19150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KW556_RS19170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KW556_RS19175	COG2011	ABC-type metal ion transport system permease component
KW556_RS19180	COG1464	Belongs to the NlpA lipoprotein family
KW556_RS19215	COG5002	protein histidine kinase activity
KW556_RS19215	COG0784	Response regulator, receiver
KW556_RS19215	COG2198	Histidine kinase
KW556_RS19250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KW556_RS19255	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KW556_RS19260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KW556_RS19265	COG2716	regulation of RNA biosynthetic process
KW556_RS19270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KW556_RS19275	COG3013	Belongs to the UPF0304 family
KW556_RS19285	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KW556_RS19290	COG0280	phosphate acetyltransferase
KW556_RS19290	COG0857	belongs to the CobB CobQ family
KW556_RS19295	COG1555	photosystem II stabilization
KW556_RS19300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KW556_RS19305	COG3104	oligopeptide transport
KW556_RS19310	COG0745	RESPONSE REGULATOR receiver
KW556_RS19340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW556_RS19355	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KW556_RS19390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KW556_RS19400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KW556_RS19405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KW556_RS19415	COG3385	transposase activity
KW556_RS19450	COG0440	acetolactate synthase activity
KW556_RS19455	COG0028	Belongs to the TPP enzyme family
KW556_RS19480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KW556_RS19485	COG0473	3-isopropylmalate dehydrogenase activity
KW556_RS19490	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KW556_RS19495	COG0066	3-isopropylmalate dehydratase activity
KW556_RS19510	COG4143	(ABC) transporter
KW556_RS19515	COG1178	ABC-type Fe3 transport system permease component
KW556_RS19520	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KW556_RS19525	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KW556_RS19585	COG0459	protein refolding
KW556_RS19590	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KW556_RS19595	COG0534	Mate efflux family protein
KW556_RS19600	COG3030	protein affecting phage T7 exclusion by the F plasmid
KW556_RS19605	COG1027	Aspartate ammonia-lyase
KW556_RS19610	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KW556_RS19615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KW556_RS19620	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KW556_RS19625	COG1610	YqeY-like protein
KW556_RS19630	COG0358	DNA primase activity
KW556_RS19635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KW556_RS19645	COG0582	viral genome integration into host DNA
KW556_RS19720	COG0151	Belongs to the GarS family
KW556_RS19725	COG0138	bifunctional purine biosynthesis protein purh
KW556_RS19735	COG3036	rescue of stalled ribosome
KW556_RS19740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KW556_RS19745	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KW556_RS19755	COG0673	inositol 2-dehydrogenase activity
KW556_RS19765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KW556_RS19770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KW556_RS19780	COG0583	DNA-binding transcription factor activity
KW556_RS19785	COG0477	Major facilitator Superfamily
KW556_RS19805	COG1028	Short-chain dehydrogenase reductase Sdr
KW556_RS19815	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KW556_RS19830	COG0456	acetyltransferase
KW556_RS19840	COG1022	Amp-dependent synthetase and ligase
KW556_RS19850	COG2918	glutathione biosynthetic process
KW556_RS19855	COG0612	Peptidase, M16
KW556_RS19860	COG1238	metal cluster binding
KW556_RS19865	COG1064	alcohol dehydrogenase
KW556_RS19890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KW556_RS19895	COG0359	binds to the 23S rRNA
KW556_RS19900	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KW556_RS19905	COG0360	Binds together with S18 to 16S ribosomal RNA
KW556_RS19910	COG1914	H( )-stimulated, divalent metal cation uptake system
KW556_RS19915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KW556_RS19925	COG0776	regulation of translation
KW556_RS19940	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KW556_RS19955	COG0560	Phosphoserine phosphatase
KW556_RS19965	COG0813	purine-nucleoside phosphorylase activity
KW556_RS19970	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KW556_RS19975	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KW556_RS19980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KW556_RS19990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KW556_RS19995	COG0084	hydrolase, TatD family'
KW556_RS20000	COG2165	general secretion pathway protein
KW556_RS20005	COG1854	S-ribosylhomocysteine lyase activity
KW556_RS20020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KW556_RS20020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KW556_RS20060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KW556_RS20065	COG1047	Peptidyl-prolyl cis-trans
KW556_RS20070	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KW556_RS20075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KW556_RS20080	COG0196	riboflavin kinase activity
KW556_RS20085	COG0728	peptidoglycan biosynthetic process
KW556_RS20090	COG0268	Binds directly to 16S ribosomal RNA
KW556_RS20095	COG0640	Transcriptional regulator
KW556_RS20100	COG0583	DNA-binding transcription factor activity
KW556_RS20110	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KW556_RS20115	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KW556_RS20120	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KW556_RS20130	COG1051	belongs to the nudix hydrolase family
KW556_RS20135	COG3066	DNA modification
KW556_RS20145	COG0335	large ribosomal subunit rRNA binding
KW556_RS20150	COG0336	Belongs to the RNA methyltransferase TrmD family
KW556_RS20155	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KW556_RS20160	COG0228	four-way junction DNA binding
KW556_RS20165	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KW556_RS20170	COG4137	Cytochrome C assembly protein
KW556_RS20175	COG4536	flavin adenine dinucleotide binding
KW556_RS20185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KW556_RS20185	COG1017	nitric oxide dioxygenase activity
KW556_RS20190	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KW556_RS20195	COG0039	L-malate dehydrogenase activity
KW556_RS20200	COG4160	amino acid transport
KW556_RS20205	COG4215	(ABC) transporter
KW556_RS20210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW556_RS20215	COG1126	abc transporter atp-binding protein
KW556_RS20220	COG1438	arginine binding
KW556_RS20225	COG2837	iron assimilation
KW556_RS20230	COG3842	ATPase activity
KW556_RS20240	COG1840	ABC-type Fe3 transport system, periplasmic component
KW556_RS20245	COG0347	Belongs to the P(II) protein family
KW556_RS20265	COG3022	response to hydroperoxide
KW556_RS20280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KW556_RS20285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KW556_RS20290	COG0762	integral membrane protein
KW556_RS20295	COG1872	DUF167
KW556_RS20305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KW556_RS20310	COG0583	DNA-binding transcription factor activity
KW556_RS20325	COG1929	Belongs to the glycerate kinase type-1 family
KW556_RS20330	COG2610	gluconate transmembrane transporter activity
KW556_RS20335	COG3835	regulator
KW556_RS20340	COG3112	Uncharacterised protein family (UPF0231)
KW556_RS20360	COG3568	Endonuclease Exonuclease Phosphatase
KW556_RS20370	COG0513	Belongs to the DEAD box helicase family
KW556_RS20395	COG0204	Acyl-transferase
KW556_RS20415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KW556_RS20420	COG0583	DNA-binding transcription factor activity
KW556_RS20455	COG3104	oligopeptide transport
KW556_RS20465	COG0583	DNA-binding transcription factor activity
KW556_RS20515	COG3150	esterase
KW556_RS20525	COG3151	Protein conserved in bacteria
KW556_RS20530	COG0494	nUDIX hydrolase
KW556_RS20535	COG1538	Outer membrane efflux protein
KW556_RS20540	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KW556_RS20540	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KW556_RS20545	COG1560	Kdo2-lipid A biosynthetic process
KW556_RS20550	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW556_RS20550	COG2213	PTS system mannitol-specific
KW556_RS20555	COG0246	Mannitol dehydrogenase
KW556_RS20560	COG3722	fumarate hydratase activity
KW556_RS20585	COG1671	Belongs to the UPF0178 family
KW556_RS20590	COG1988	membrane-bound metal-dependent
KW556_RS20595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KW556_RS20600	COG0513	Belongs to the DEAD box helicase family
KW556_RS20620	COG1575	Belongs to the MenA family. Type 1 subfamily
KW556_RS20625	COG1169	isochorismate synthase
KW556_RS20630	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KW556_RS20635	COG0596	Alpha beta hydrolase
KW556_RS20640	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KW556_RS20645	COG1441	menaquinone biosynthetic process
KW556_RS20650	COG0318	PFAM AMP-dependent synthetase and ligase
KW556_RS20655	COG3291	Pkd domain containing protein
KW556_RS20660	COG2949	membrane
KW556_RS20665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KW556_RS20675	COG0784	Response regulator, receiver
KW556_RS20675	COG0835	chemotaxis
KW556_RS20685	COG1444	tRNA N-acetyltransferase activity
KW556_RS20705	COG1803	Methylglyoxal synthase
KW556_RS20710	COG1979	alcohol dehydrogenase
KW556_RS20725	COG4221	oxidoreductase activity
KW556_RS20765	COG1368	sulfuric ester hydrolase activity
KW556_RS20770	COG1522	sequence-specific DNA binding
KW556_RS20780	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KW556_RS20785	COG1418	mRNA catabolic process
KW556_RS20790	COG1058	Belongs to the CinA family
KW556_RS20790	COG1546	Belongs to the CinA family
KW556_RS20800	COG0561	phosphatase activity
KW556_RS20810	COG2926	Belongs to the UPF0265 family
KW556_RS20840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KW556_RS20845	COG0564	pseudouridine synthase activity
KW556_RS20855	COG0110	maltose O-acetyltransferase activity
KW556_RS20860	COG0366	Alpha amylase catalytic
KW556_RS20865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KW556_RS20865	COG1263	PTS System
KW556_RS20885	COG0252	asparaginase activity
KW556_RS20890	COG1253	flavin adenine dinucleotide binding
KW556_RS20895	COG0586	Pfam SNARE associated Golgi protein
KW556_RS20900	COG1686	Belongs to the peptidase S11 family
KW556_RS20935	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KW556_RS20940	COG0527	aspartate kinase activity
KW556_RS20945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KW556_RS20955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KW556_RS20960	COG1546	Belongs to the CinA family
KW556_RS20970	COG5377	YqaJ viral recombinase family
KW556_RS21015	COG2003	Belongs to the UPF0758 family
KW556_RS21080	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KW556_RS21125	COG4467	Involved in initiation control of chromosome replication
KW556_RS21135	COG4644	lycopene metabolic process
KW556_RS21145	COG0840	transmembrane signaling receptor activity
KW556_RS21155	COG3039	Transposase
KW556_RS21160	COG3706	GGDEF domain
KW556_RS21215	COG0582	viral genome integration into host DNA
KW556_RS21220	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KW556_RS21225	COG4667	esterase of the alpha-beta hydrolase superfamily
KW556_RS21235	COG1346	cytolysis
KW556_RS21240	COG1380	Effector of murein hydrolase LrgA
KW556_RS21245	COG0583	DNA-binding transcription factor activity
KW556_RS21255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KW556_RS21285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KW556_RS21290	COG2022	thiamine diphosphate biosynthetic process
KW556_RS21300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KW556_RS21305	COG0352	thiamine-phosphate diphosphorylase activity
KW556_RS21310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KW556_RS21330	COG0745	RESPONSE REGULATOR receiver
KW556_RS21335	COG0642	Histidine kinase
KW556_RS21340	COG0189	ligase activity
KW556_RS21385	COG0477	Major facilitator Superfamily
KW556_RS21400	COG0312	modulator of DNA gyrase
KW556_RS21405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KW556_RS21415	COG3164	Protein of unknown function
KW556_RS21420	COG1530	ribonuclease E activity
KW556_RS21430	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KW556_RS21435	COG1792	Involved in formation and maintenance of cell shape
KW556_RS21440	COG1077	Cell shape determining protein MreB Mrl
KW556_RS21470	COG2165	general secretion pathway protein
KW556_RS21485	COG1459	type II secretion system
KW556_RS21490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KW556_RS21500	COG2842	Transposition protein
KW556_RS21535	COG2199	diguanylate cyclase activity
KW556_RS21535	COG2200	EAL domain
KW556_RS21540	COG2200	EAL domain
KW556_RS21545	COG0387	Pfam Sodium calcium exchanger
KW556_RS21550	COG2986	histidine ammonia-lyase
KW556_RS21555	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KW556_RS21560	COG0010	Belongs to the arginase family
KW556_RS21565	COG1228	amidohydrolase
KW556_RS21570	COG2188	Transcriptional regulator
KW556_RS21575	COG0288	reversible hydration of carbon dioxide
KW556_RS21585	COG2177	Part of the ABC transporter FtsEX involved in
KW556_RS21590	COG2884	Cell division ATP-binding protein ftsE
KW556_RS21595	COG0552	protein localization to endoplasmic reticulum
KW556_RS21600	COG0742	ribosomal rna small subunit methyltransferase
KW556_RS21625	COG2249	NAD(P)H dehydrogenase (quinone) activity
KW556_RS21630	COG0583	DNA-binding transcription factor activity
KW556_RS21635	COG4221	oxidoreductase activity
KW556_RS21650	COG1770	oligopeptidase
KW556_RS21665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KW556_RS21675	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KW556_RS21685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KW556_RS21695	COG2095	MarC family integral membrane protein
KW556_RS21705	COG1301	dicarboxylic acid transport
KW556_RS21730	COG3714	YhhN family
KW556_RS21780	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KW556_RS21785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KW556_RS21790	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KW556_RS21795	COG0049	tRNA binding
KW556_RS21800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KW556_RS21805	COG2168	tRNA wobble position uridine thiolation
KW556_RS21810	COG2923	Belongs to the DsrF TusC family
KW556_RS21815	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KW556_RS21825	COG2964	Protein conserved in bacteria
KW556_RS21830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KW556_RS21835	COG0085	RNA polymerase activity
KW556_RS21840	COG0222	ribosome binding
KW556_RS21845	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KW556_RS21850	COG0081	regulation of translation
KW556_RS21855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KW556_RS21860	COG0250	Participates in transcription elongation, termination and antitermination
KW556_RS21875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KW556_RS21905	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KW556_RS21910	COG0569	domain protein
KW556_RS21915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KW556_RS21930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW556_RS21930	COG4191	Histidine kinase
KW556_RS21935	COG3005	denitrification pathway
KW556_RS21940	COG0243	molybdopterin cofactor binding
KW556_RS21985	COG2204	response regulator
KW556_RS21995	COG2205	protein histidine kinase activity
KW556_RS22010	COG1028	Short-chain dehydrogenase reductase Sdr
KW556_RS22015	COG0517	IMP dehydrogenase activity
KW556_RS22015	COG0516	GMP reductase activity
KW556_RS22020	COG5413	integral membrane protein
KW556_RS22030	COG1522	sequence-specific DNA binding
KW556_RS22035	COG2502	aspartate--ammonia ligase
KW556_RS22040	COG0542	response to heat
KW556_RS22050	COG0564	pseudouridine synthase activity
KW556_RS22055	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KW556_RS22060	COG3385	transposase activity
KW556_RS22065	COG0446	pyridine nucleotide-disulphide oxidoreductase
KW556_RS22075	COG3681	Belongs to the UPF0597 family
KW556_RS22080	COG2964	Protein conserved in bacteria
KW556_RS22090	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KW556_RS22095	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KW556_RS22100	COG1979	alcohol dehydrogenase
KW556_RS22105	COG2207	Transcriptional regulator
KW556_RS22125	COG0583	DNA-binding transcription factor activity
KW556_RS22145	COG0540	Belongs to the ATCase OTCase family
KW556_RS22150	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KW556_RS22155	COG1438	arginine binding
KW556_RS22160	COG1288	antiporter activity
KW556_RS22165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KW556_RS22210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KW556_RS22220	COG3078	GTPase activator activity
KW556_RS22230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KW556_RS22250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KW556_RS22255	COG0408	coproporphyrinogen oxidase activity
KW556_RS22260	COG0009	L-threonylcarbamoyladenylate synthase
KW556_RS22270	COG0551	DNA topoisomerase type I activity
KW556_RS22275	COG2922	Belongs to the Smg family
KW556_RS22280	COG0758	DNA mediated transformation
KW556_RS22285	COG1652	LysM domain
KW556_RS22290	COG0242	peptide deformylase activity
KW556_RS22295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KW556_RS22300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KW556_RS22300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KW556_RS22305	COG0569	domain protein
KW556_RS22310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KW556_RS22315	COG1217	gtp-binding protein TYPA
KW556_RS22320	COG0174	glutamine synthetase
KW556_RS22335	COG2204	response regulator
KW556_RS22340	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KW556_RS22345	COG1322	Protein conserved in bacteria
KW556_RS22365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KW556_RS22370	COG0583	DNA-binding transcription factor activity
KW556_RS22375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KW556_RS22375	COG0519	Catalyzes the synthesis of GMP from XMP
KW556_RS22385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KW556_RS22390	COG1396	sequence-specific DNA binding
KW556_RS22395	COG1012	belongs to the aldehyde dehydrogenase family
KW556_RS22405	COG2962	Rard protein
KW556_RS22410	COG0840	transmembrane signaling receptor activity
KW556_RS22415	COG2391	methyltransferase activity
KW556_RS22420	COG2885	chlorophyll binding
KW556_RS22420	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KW556_RS22430	COG0129	dihydroxy-acid dehydratase activity
KW556_RS22440	COG3978	acetolactate synthase activity
KW556_RS22450	COG0606	chelatase, subunit chli
KW556_RS22455	COG0204	Acyl-transferase
KW556_RS22460	COG0204	Acyl-transferase
KW556_RS22465	COG1683	Conserved Protein
KW556_RS22475	COG1335	isochorismatase
KW556_RS22485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KW556_RS22490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KW556_RS22500	COG3084	Protein conserved in bacteria
KW556_RS22505	COG2203	Gaf domain
KW556_RS22505	COG3706	GGDEF domain
KW556_RS22505	COG4251	negative regulation of phosphorylation
KW556_RS22505	COG5001	Diguanylate cyclase
KW556_RS22520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KW556_RS22525	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KW556_RS22530	COG1561	YicC-like family, N-terminal region
KW556_RS22535	COG0583	DNA-binding transcription factor activity
KW556_RS22555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KW556_RS22560	COG0385	Bile acid
KW556_RS22565	COG0531	amino acid
KW556_RS22570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KW556_RS22575	COG0531	amino acid
KW556_RS22580	COG2731	YhcH YjgK YiaL family protein
KW556_RS22585	COG3250	beta-galactosidase activity
KW556_RS22590	COG1609	Transcriptional regulator
KW556_RS22625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KW556_RS22630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KW556_RS22630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KW556_RS22635	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KW556_RS22640	COG3074	FtsZ-dependent cytokinesis
KW556_RS22650	COG1045	serine acetyltransferase
KW556_RS22660	COG0745	RESPONSE REGULATOR receiver
KW556_RS22665	COG2205	protein histidine kinase activity
KW556_RS22670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KW556_RS22675	COG0534	Mate efflux family protein
KW556_RS22695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KW556_RS22700	COG2937	Belongs to the GPAT DAPAT family
KW556_RS22705	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KW556_RS22710	COG3161	chorismate lyase activity
KW556_RS22735	COG0604	alcohol dehydrogenase
KW556_RS22740	COG1609	Transcriptional regulator
KW556_RS22745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW556_RS22760	COG1519	Transferase
KW556_RS22765	COG0859	PFAM glycosyl transferase family 9
KW556_RS22770	COG0463	Glycosyl transferase, family 2
KW556_RS22775	COG0859	PFAM glycosyl transferase family 9
KW556_RS22780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KW556_RS22785	COG2990	Protein conserved in bacteria
KW556_RS22790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KW556_RS22800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KW556_RS22805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KW556_RS22810	COG2003	Belongs to the UPF0758 family
KW556_RS22815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KW556_RS22820	COG0756	dUTP diphosphatase activity
KW556_RS22825	COG1309	transcriptional regulator
KW556_RS22830	COG0668	transmembrane transport
KW556_RS22835	COG0166	Belongs to the GPI family
KW556_RS22840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KW556_RS22860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KW556_RS22860	COG1042	CoA-binding domain protein
KW556_RS22860	COG0045	succinate-CoA ligase (ADP-forming) activity
KW556_RS22890	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KW556_RS22895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KW556_RS22900	COG1739	Uncharacterized protein family UPF0029
KW556_RS22905	COG0006	proline dipeptidase activity
KW556_RS22910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KW556_RS22915	COG1250	3-hydroxyacyl-CoA dehydrogenase
KW556_RS22915	COG1024	Enoyl-CoA hydratase
KW556_RS22920	COG0183	Belongs to the thiolase family
KW556_RS22945	COG0425	Belongs to the sulfur carrier protein TusA family
KW556_RS22950	COG0251	oxidation-reduction process
KW556_RS22955	COG2885	chlorophyll binding
KW556_RS22960	COG2818	Glycosylase
KW556_RS22965	COG0752	glycyl-tRNA synthetase alpha subunit
KW556_RS22970	COG0751	glycine-tRNA ligase activity
KW556_RS22975	COG1192	Involved in chromosome partitioning
KW556_RS23000	COG3385	transposase activity
KW556_RS23030	COG1609	Transcriptional regulator
KW556_RS23060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KW556_RS23070	COG2960	long-chain fatty acid transporting porin activity
KW556_RS23075	COG5001	Diguanylate cyclase
KW556_RS23085	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KW556_RS23100	COG3118	belongs to the thioredoxin family
KW556_RS23105	COG0513	Belongs to the DEAD box helicase family
KW556_RS23110	COG0248	Ppx GppA phosphatase
KW556_RS23120	COG0742	ribosomal rna small subunit methyltransferase
KW556_RS23145	COG0084	hydrolase, TatD family'
KW556_RS23150	COG0805	protein transport
KW556_RS23155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KW556_RS23160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KW556_RS23165	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KW556_RS23170	COG3165	ubiquinone biosynthetic process from chorismate
KW556_RS23175	COG2226	methyltransferase
KW556_RS23180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KW556_RS23185	COG0402	S-adenosylhomocysteine deaminase activity
KW556_RS23190	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KW556_RS23230	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KW556_RS23235	COG0848	biopolymer transport protein
KW556_RS23240	COG0811	peptide transport
KW556_RS23245	COG0811	peptide transport
KW556_RS23255	COG2771	luxR family
KW556_RS23270	COG1349	DNA-binding transcription factor activity
KW556_RS23280	COG1028	Short-chain dehydrogenase reductase Sdr
KW556_RS23340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KW556_RS23345	COG1349	DNA-binding transcription factor activity
KW556_RS23350	COG0745	RESPONSE REGULATOR receiver
KW556_RS23355	COG2205	protein histidine kinase activity
KW556_RS23370	COG4452	Inner membrane protein CreD
KW556_RS23375	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KW556_RS23380	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KW556_RS23385	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KW556_RS23390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KW556_RS23395	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KW556_RS23400	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KW556_RS23405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KW556_RS23415	COG0356	it plays a direct role in the translocation of protons across the membrane
KW556_RS23425	COG1475	DNA binding
KW556_RS23430	COG1192	Involved in chromosome partitioning
KW556_RS23435	COG0357	Ribosomal RNA small subunit methyltransferase G
KW556_RS23440	COG0445	tRNA wobble uridine modification
KW556_RS23445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KW556_RS23455	COG4615	Cyclic peptide transporter
KW556_RS23460	COG1120	ATPase activity
KW556_RS23475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KW556_RS23485	COG3550	peptidyl-serine autophosphorylation
KW556_RS23505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KW556_RS23510	COG3041	Addiction module toxin RelE StbE family
KW556_RS23520	COG1879	ABC-type sugar transport system periplasmic component
KW556_RS23550	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KW556_RS23590	COG4974	Belongs to the 'phage' integrase family
KW556_RS23595	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KW556_RS23600	COG0706	membrane insertase activity
KW556_RS23605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KW556_RS23610	COG0594	ribonuclease P activity
KW556_RS23615	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KW556_RS23675	COG2026	Addiction module toxin, RelE StbE family
KW556_RS23680	COG3077	Addiction module antitoxin, RelB DinJ family
KW556_RS23685	COG1192	Involved in chromosome partitioning
KW556_RS23930	COG2176	DNA-directed DNA polymerase activity
KW556_RS23930	COG5002	protein histidine kinase activity
KW556_RS24035	COG3385	transposase activity
KW556_RS24065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KW556_RS24070	COG0625	glutathione transferase activity
KW556_RS24095	COG1192	Involved in chromosome partitioning