locus-tag	class	description
FGM04_RS00005	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_RS00005	COG1454	alcohol dehydrogenase
FGM04_RS00010	COG2095	MarC family integral membrane protein
FGM04_RS00020	COG0601	transmembrane transport
FGM04_RS00025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGM04_RS00040	COG0861	Integral membrane protein TerC family
FGM04_RS00045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGM04_RS00075	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FGM04_RS00085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGM04_RS00090	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FGM04_RS00095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGM04_RS00100	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FGM04_RS00105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FGM04_RS00120	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FGM04_RS00125	COG0505	Belongs to the CarA family
FGM04_RS00130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGM04_RS00180	COG0346	lactoylglutathione lyase activity
FGM04_RS00185	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FGM04_RS00190	COG4660	Part of a membrane complex involved in electron transport
FGM04_RS00195	COG4659	FMN binding
FGM04_RS00200	COG4658	electron transport chain
FGM04_RS00210	COG2878	Part of a membrane complex involved in electron transport
FGM04_RS00215	COG4657	Part of a membrane complex involved in electron transport
FGM04_RS00220	COG1061	Type III restriction enzyme res subunit
FGM04_RS00230	COG0346	lactoylglutathione lyase activity
FGM04_RS00240	COG0583	DNA-binding transcription factor activity
FGM04_RS00250	COG0840	transmembrane signaling receptor activity
FGM04_RS00255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FGM04_RS00260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGM04_RS00265	COG2271	Major facilitator Superfamily
FGM04_RS00270	COG1349	DNA-binding transcription factor activity
FGM04_RS00280	COG0584	glycerophosphoryl diester phosphodiesterase
FGM04_RS00285	COG4574	serine-type endopeptidase inhibitor activity
FGM04_RS00290	COG3085	chromosome segregation
FGM04_RS00295	COG0583	DNA-binding transcription factor activity
FGM04_RS00305	COG1448	Aminotransferase
FGM04_RS00320	COG0658	competence protein
FGM04_RS00320	COG2333	competence protein COMEC
FGM04_RS00330	COG1663	tetraacyldisaccharide 4'-kinase activity
FGM04_RS00335	COG2835	tetraacyldisaccharide 4'-kinase activity
FGM04_RS00340	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FGM04_RS00345	COG2197	response regulator
FGM04_RS00350	COG0322	excinuclease ABC activity
FGM04_RS00375	COG0582	viral genome integration into host DNA
FGM04_RS00420	COG4869	propanediol catabolic process
FGM04_RS00430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGM04_RS00435	COG1882	Formate acetyltransferase
FGM04_RS00440	COG1454	alcohol dehydrogenase
FGM04_RS00440	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_RS00450	COG1454	alcohol dehydrogenase
FGM04_RS00450	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_RS00485	COG1349	DNA-binding transcription factor activity
FGM04_RS00490	COG2084	Dehydrogenase
FGM04_RS00500	COG3039	Transposase
FGM04_RS00520	COG0235	Class ii aldolase
FGM04_RS00550	COG2801	Transposase and inactivated derivatives
FGM04_RS00580	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGM04_RS00590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGM04_RS00595	COG0215	cysteine-tRNA ligase activity
FGM04_RS00600	COG0210	DNA helicase
FGM04_RS00605	COG3039	Transposase
FGM04_RS00640	COG2119	membrane
FGM04_RS00645	COG0023	Translation Initiation Factor
FGM04_RS00670	COG0513	Belongs to the DEAD box helicase family
FGM04_RS00685	COG0493	'glutamate synthase
FGM04_RS00690	COG0069	glutamate synthase activity
FGM04_RS00690	COG0070	glutamate synthase
FGM04_RS00690	COG0067	glutamate synthase
FGM04_RS00695	COG1242	4 iron, 4 sulfur cluster binding
FGM04_RS00735	COG1464	Belongs to the NlpA lipoprotein family
FGM04_RS00740	COG3083	sulfuric ester hydrolase activity
FGM04_RS00745	COG3082	Protein of unknown function (DUF1414)
FGM04_RS00750	COG3081	Nucleoid-associated protein
FGM04_RS00760	COG1175	transmembrane transport
FGM04_RS00765	COG3833	ABC-type maltose transport systems, permease component
FGM04_RS00770	COG3842	ATPase activity
FGM04_RS00795	COG0425	Belongs to the sulfur carrier protein TusA family
FGM04_RS00800	COG4783	chaperone-mediated protein folding
FGM04_RS00810	COG1393	Belongs to the ArsC family
FGM04_RS00820	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FGM04_RS00830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_RS00835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FGM04_RS00840	COG2431	L-lysine efflux transmembrane transporter activity
FGM04_RS00850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_RS00860	COG4160	amino acid transport
FGM04_RS00865	COG0564	pseudouridine synthase activity
FGM04_RS00880	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FGM04_RS00890	COG0625	glutathione transferase activity
FGM04_RS00930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGM04_RS00960	COG0367	asparagine synthase
FGM04_RS00970	COG4651	solute:proton antiporter activity
FGM04_RS00970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FGM04_RS00975	COG0647	UMP catabolic process
FGM04_RS00990	COG1902	pentaerythritol trinitrate reductase activity
FGM04_RS00995	COG1253	flavin adenine dinucleotide binding
FGM04_RS01005	COG0247	lactate metabolic process
FGM04_RS01005	COG0277	FAD linked oxidase domain protein
FGM04_RS01015	COG2050	protein possibly involved in aromatic compounds catabolism
FGM04_RS01025	COG2056	Na+-H+ antiporter family
FGM04_RS01030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FGM04_RS01035	COG0671	phosphoesterase, PA-phosphatase related
FGM04_RS01040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGM04_RS01045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGM04_RS01055	COG0101	tRNA pseudouridine synthase activity
FGM04_RS01060	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FGM04_RS01065	COG0285	dihydrofolate synthase activity
FGM04_RS01070	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FGM04_RS01075	COG0393	Putative heavy-metal-binding
FGM04_RS01085	COG1648	precorrin-2 dehydrogenase activity
FGM04_RS01085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGM04_RS01105	COG4667	esterase of the alpha-beta hydrolase superfamily
FGM04_RS01110	COG1619	proteins homologs of microcin C7 resistance protein MccF
FGM04_RS01115	COG1368	sulfuric ester hydrolase activity
FGM04_RS01125	COG0527	aspartate kinase activity
FGM04_RS01130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGM04_RS01130	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FGM04_RS01135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGM04_RS01155	COG0596	Alpha beta hydrolase
FGM04_RS01175	COG0577	efflux transmembrane transporter activity
FGM04_RS01180	COG1136	(ABC) transporter
FGM04_RS01195	COG2814	Major facilitator Superfamily
FGM04_RS01220	COG0672	)-iron permease
FGM04_RS01240	COG0514	ATP-dependent DNA helicase (RecQ)
FGM04_RS01265	COG0659	secondary active sulfate transmembrane transporter activity
FGM04_RS01280	COG4974	Belongs to the 'phage' integrase family
FGM04_RS01285	COG3039	Transposase
FGM04_RS01320	COG3039	Transposase
FGM04_RS01335	COG5642	Protein of unknown function (DUF2384)
FGM04_RS01375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FGM04_RS01375	COG0392	lysyltransferase activity
FGM04_RS01385	COG2205	protein histidine kinase activity
FGM04_RS01390	COG0745	RESPONSE REGULATOR receiver
FGM04_RS01410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FGM04_RS01415	COG1278	Cold shock
FGM04_RS01420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FGM04_RS01425	COG0542	response to heat
FGM04_RS01430	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FGM04_RS01435	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FGM04_RS01440	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FGM04_RS01445	COG3134	Outer membrane lipoprotein
FGM04_RS01450	COG3706	GGDEF domain
FGM04_RS01455	COG0492	ferredoxin-NADP+ reductase activity
FGM04_RS01460	COG0686	Belongs to the AlaDH PNT family
FGM04_RS01470	COG1674	ftsk spoiiie
FGM04_RS01470	COG0531	amino acid
FGM04_RS01475	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FGM04_RS01480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FGM04_RS01485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGM04_RS01495	COG1286	toxin biosynthetic process
FGM04_RS01500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FGM04_RS01510	COG0563	adenylate kinase activity
FGM04_RS01515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FGM04_RS01525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGM04_RS01540	COG5001	Diguanylate cyclase
FGM04_RS01540	COG3300	MHYT domain
FGM04_RS01590	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FGM04_RS01595	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FGM04_RS01600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGM04_RS01615	COG0513	Belongs to the DEAD box helicase family
FGM04_RS01620	COG0386	Belongs to the glutathione peroxidase family
FGM04_RS01630	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGM04_RS01635	COG0383	alpha-mannosidase activity
FGM04_RS01640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_RS01640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_RS01640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_RS01645	COG2188	Transcriptional regulator
FGM04_RS01655	COG0488	(ABC) transporter
FGM04_RS01760	COG1025	Belongs to the peptidase M16 family
FGM04_RS01765	COG2062	phosphohistidine phosphatase, SixA
FGM04_RS01775	COG0697	spore germination
FGM04_RS01780	COG4166	transmembrane transport
FGM04_RS01785	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FGM04_RS01790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FGM04_RS01800	COG4591	ABC-type transport system involved in lipoprotein release permease component
FGM04_RS01805	COG1136	(ABC) transporter
FGM04_RS01810	COG4591	ABC-type transport system involved in lipoprotein release permease component
FGM04_RS01815	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FGM04_RS01825	COG0544	peptidyl-prolyl cis-trans isomerase activity
FGM04_RS01830	COG0740	serine-type endopeptidase activity
FGM04_RS01835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FGM04_RS01840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FGM04_RS01845	COG0776	regulation of translation
FGM04_RS01850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGM04_RS01855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGM04_RS01860	COG1215	transferase activity, transferring glycosyl groups
FGM04_RS01865	COG0438	transferase activity, transferring glycosyl groups
FGM04_RS01890	COG1570	exodeoxyribonuclease VII activity
FGM04_RS01895	COG3038	cytochrome b561
FGM04_RS01900	COG0516	GMP reductase activity
FGM04_RS01900	COG0517	IMP dehydrogenase activity
FGM04_RS01905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FGM04_RS01905	COG0519	Catalyzes the synthesis of GMP from XMP
FGM04_RS01940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGM04_RS01945	COG3162	membrane
FGM04_RS01960	COG1024	Enoyl-CoA hydratase
FGM04_RS01965	COG1115	amino acid carrier protein
FGM04_RS01990	COG0058	SHG alpha-glucan phosphorylase activity
FGM04_RS01995	COG0471	metal ion transport
FGM04_RS02000	COG3118	belongs to the thioredoxin family
FGM04_RS02010	COG1132	(ABC) transporter
FGM04_RS02015	COG1132	(ABC) transporter
FGM04_RS02025	COG2501	S4 domain
FGM04_RS02040	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FGM04_RS02085	COG2009	succinate dehydrogenase
FGM04_RS02090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FGM04_RS02095	COG1053	succinate dehydrogenase
FGM04_RS02105	COG0567	Dehydrogenase, E1 component
FGM04_RS02110	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGM04_RS02115	COG0045	succinate-CoA ligase (ADP-forming) activity
FGM04_RS02135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_RS02145	COG3842	ATPase activity
FGM04_RS02150	COG1840	ABC-type Fe3 transport system, periplasmic component
FGM04_RS02160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FGM04_RS02165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FGM04_RS02170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGM04_RS02185	COG4235	cytochrome complex assembly
FGM04_RS02185	COG3088	subunit of a heme lyase
FGM04_RS02195	COG1138	Cytochrome C-type biogenesis protein
FGM04_RS02200	COG3301	Polysulphide reductase, NrfD
FGM04_RS02205	COG0437	4 iron, 4 sulfur cluster binding
FGM04_RS02210	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FGM04_RS02220	COG0247	lactate metabolic process
FGM04_RS02225	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FGM04_RS02230	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FGM04_RS02235	COG3012	SEC-C Motif Domain Protein
FGM04_RS02240	COG0840	transmembrane signaling receptor activity
FGM04_RS02245	COG1940	carbohydrate kinase activity
FGM04_RS02245	COG1846	Transcriptional regulator
FGM04_RS02250	COG3148	PFAM DTW domain containing protein
FGM04_RS02255	COG0730	response to heat
FGM04_RS02260	COG0583	DNA-binding transcription factor activity
FGM04_RS02275	COG3593	DNA synthesis involved in DNA repair
FGM04_RS02325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FGM04_RS02330	COG1011	Hydrolase
FGM04_RS02345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGM04_RS02350	COG2832	Protein of unknown function (DUF454)
FGM04_RS02355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGM04_RS02365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FGM04_RS02370	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FGM04_RS02385	COG1560	Kdo2-lipid A biosynthetic process
FGM04_RS02390	COG1560	Kdo2-lipid A biosynthetic process
FGM04_RS02415	COG0417	DNA replication proofreading
FGM04_RS02430	COG1451	nucleotide metabolic process
FGM04_RS02445	COG3069	C4-dicarboxylate transmembrane transporter activity
FGM04_RS02460	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FGM04_RS02460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_RS02465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGM04_RS02470	COG0569	domain protein
FGM04_RS02470	COG2985	domain, Protein
FGM04_RS02485	COG0556	nucleotide-excision repair
FGM04_RS02495	COG0586	Pfam SNARE associated Golgi protein
FGM04_RS02500	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FGM04_RS02505	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGM04_RS02520	COG4681	YaeQ
FGM04_RS02535	COG3829	transcription factor binding
FGM04_RS02575	COG0307	riboflavin synthase, alpha
FGM04_RS02585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGM04_RS02590	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FGM04_RS02595	COG0697	spore germination
FGM04_RS02600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FGM04_RS02640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGM04_RS02645	COG3099	Belongs to the UPF0263 family
FGM04_RS02650	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FGM04_RS02655	COG2894	cell division
FGM04_RS02660	COG0850	regulation of cytokinetic process
FGM04_RS02665	COG3100	YcgL domain-containing protein
FGM04_RS02670	COG1760	l-serine dehydratase
FGM04_RS02675	COG1760	l-serine dehydratase
FGM04_RS02680	COG3123	guanosine phosphorylase activity
FGM04_RS02690	COG0205	6-phosphofructokinase activity
FGM04_RS02700	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FGM04_RS02705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FGM04_RS02715	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FGM04_RS02720	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FGM04_RS02725	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FGM04_RS02740	COG0242	peptide deformylase activity
FGM04_RS02775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGM04_RS02780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FGM04_RS02785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGM04_RS02795	COG0549	Belongs to the carbamate kinase family
FGM04_RS02810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGM04_RS02815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGM04_RS02820	COG0697	spore germination
FGM04_RS02825	COG3385	transposase activity
FGM04_RS02830	COG0366	Alpha amylase catalytic
FGM04_RS02845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FGM04_RS02850	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FGM04_RS02855	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FGM04_RS02860	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FGM04_RS02865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FGM04_RS02870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGM04_RS02870	COG0072	phenylalanine-tRNA ligase activity
FGM04_RS02875	COG0776	regulation of translation
FGM04_RS02880	COG0784	Response regulator, receiver
FGM04_RS02880	COG2205	protein histidine kinase activity
FGM04_RS02915	COG2199	diguanylate cyclase activity
FGM04_RS02920	COG1609	Transcriptional regulator
FGM04_RS02925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGM04_RS02930	COG1879	ABC-type sugar transport system periplasmic component
FGM04_RS02935	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGM04_RS02940	COG1129	ABC transporter
FGM04_RS02945	COG1869	D-ribose catabolic process
FGM04_RS02950	COG0625	glutathione transferase activity
FGM04_RS02965	COG1177	transmembrane transport
FGM04_RS02990	COG0037	tRNA processing
FGM04_RS02995	COG0589	response to stress
FGM04_RS03000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGM04_RS03015	COG2217	Heavy metal translocating P-type atpase
FGM04_RS03025	COG2010	Cytochrome c
FGM04_RS03040	COG3278	Belongs to the heme-copper respiratory oxidase family
FGM04_RS03050	COG1956	GAF domain-containing protein
FGM04_RS03055	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FGM04_RS03065	COG0308	aminopeptidase N
FGM04_RS03075	COG2902	Dehydrogenase
FGM04_RS03080	COG0167	dihydroorotate dehydrogenase activity
FGM04_RS03090	COG0254	rRNA binding
FGM04_RS03095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGM04_RS03100	COG0116	Belongs to the methyltransferase superfamily
FGM04_RS03100	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FGM04_RS03110	COG0488	(ABC) transporter
FGM04_RS03120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGM04_RS03125	COG1067	ATP-dependent peptidase activity
FGM04_RS03170	COG4128	Pfam Zonular occludens toxin
FGM04_RS03255	COG3141	response to X-ray
FGM04_RS03260	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FGM04_RS03265	COG4221	oxidoreductase activity
FGM04_RS03310	COG0372	Belongs to the citrate synthase family
FGM04_RS03315	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FGM04_RS03325	COG2995	paraquat-inducible protein a
FGM04_RS03330	COG3008	intermembrane lipid transfer
FGM04_RS03335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGM04_RS03335	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FGM04_RS03350	COG0084	hydrolase, TatD family'
FGM04_RS03355	COG0470	DNA polymerase III
FGM04_RS03360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FGM04_RS03365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FGM04_RS03370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGM04_RS03375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGM04_RS03380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGM04_RS03385	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_RS03395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGM04_RS03400	COG0416	fatty acid biosynthetic process
FGM04_RS03405	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FGM04_RS03410	COG1399	metal-binding, possibly nucleic acid-binding protein
FGM04_RS03415	COG0424	maF-like protein
FGM04_RS03430	COG1530	ribonuclease E activity
FGM04_RS03440	COG0306	phosphate transporter
FGM04_RS03445	COG0717	Belongs to the dCTP deaminase family
FGM04_RS03450	COG0572	uridine kinase
FGM04_RS03455	COG0489	protein tyrosine kinase activity
FGM04_RS03460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGM04_RS03460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGM04_RS03470	COG1254	Belongs to the acylphosphatase family
FGM04_RS03480	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FGM04_RS03495	COG0709	Synthesizes selenophosphate from selenide and ATP
FGM04_RS03500	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FGM04_RS03505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGM04_RS03515	COG0318	PFAM AMP-dependent synthetase and ligase
FGM04_RS03520	COG2267	carboxylic ester hydrolase activity
FGM04_RS03530	COG1214	PFAM Peptidase M22, glycoprotease
FGM04_RS03535	COG1199	ATP-dependent helicase activity
FGM04_RS03545	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FGM04_RS03550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FGM04_RS03555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGM04_RS03560	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FGM04_RS03560	COG0131	Imidazoleglycerol-phosphate dehydratase
FGM04_RS03565	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FGM04_RS03570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FGM04_RS03575	COG0107	imidazoleglycerol-phosphate synthase activity
FGM04_RS03590	COG2199	diguanylate cyclase activity
FGM04_RS03595	COG0318	PFAM AMP-dependent synthetase and ligase
FGM04_RS03605	COG3134	Outer membrane lipoprotein
FGM04_RS03610	COG2080	2 iron, 2 sulfur cluster binding
FGM04_RS03615	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FGM04_RS03620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGM04_RS03625	COG2252	PERMEase
FGM04_RS03630	COG0402	S-adenosylhomocysteine deaminase activity
FGM04_RS03635	COG2233	PERMEase
FGM04_RS03640	COG2080	2 iron, 2 sulfur cluster binding
FGM04_RS03640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGM04_RS03645	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FGM04_RS03650	COG0402	S-adenosylhomocysteine deaminase activity
FGM04_RS03655	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGM04_RS03655	COG0493	'glutamate synthase
FGM04_RS03660	COG2068	MobA-Related Protein
FGM04_RS03665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGM04_RS03670	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FGM04_RS03670	COG3608	succinylglutamate desuccinylase aspartoacylase
FGM04_RS03680	COG3385	transposase activity
FGM04_RS03690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FGM04_RS03700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGM04_RS03710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGM04_RS03715	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FGM04_RS03720	COG3313	Fe-S protein
FGM04_RS03725	COG2942	2-epimerase
FGM04_RS03730	COG3716	PTS system mannose fructose sorbose family IID component
FGM04_RS03735	COG3715	PTS system
FGM04_RS03740	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_RS03740	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_RS03755	COG1609	Transcriptional regulator
FGM04_RS03760	COG2140	Oxalate decarboxylase
FGM04_RS03765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_RS03765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_RS03765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FGM04_RS03770	COG1105	Belongs to the carbohydrate kinase PfkB family
FGM04_RS03775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_RS03775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_RS03780	COG1609	Transcriptional regulator
FGM04_RS03785	COG0814	amino acid
FGM04_RS03795	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FGM04_RS03805	COG0513	Belongs to the DEAD box helicase family
FGM04_RS03815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FGM04_RS03820	COG2890	protein-(glutamine-N5) methyltransferase activity
FGM04_RS03825	COG2840	Smr protein MutS2
FGM04_RS03830	COG3706	GGDEF domain
FGM04_RS03835	COG0406	alpha-ribazole phosphatase activity
FGM04_RS03840	COG3791	Glutathione-dependent formaldehyde-activating
FGM04_RS03855	COG2824	Alkylphosphonate utilization operon protein PhnA
FGM04_RS03875	COG0814	amino acid
FGM04_RS03880	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FGM04_RS03885	COG0514	ATP-dependent DNA helicase (RecQ)
FGM04_RS03890	COG2766	serine protein kinase
FGM04_RS03895	COG2718	Belongs to the UPF0229 family
FGM04_RS03900	COG2719	SpoVR family
FGM04_RS03905	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGM04_RS03905	COG1024	Enoyl-CoA hydratase
FGM04_RS03910	COG0183	Belongs to the thiolase family
FGM04_RS03915	COG0714	Associated with various cellular activities
FGM04_RS03935	COG2304	oxidoreductase activity
FGM04_RS03945	COG1595	DNA-templated transcription, initiation
FGM04_RS03955	COG2067	long-chain fatty acid transport protein
FGM04_RS03960	COG2067	long-chain fatty acid transport protein
FGM04_RS03965	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FGM04_RS03980	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FGM04_RS03990	COG1643	Atp-dependent helicase
FGM04_RS03995	COG0517	IMP dehydrogenase activity
FGM04_RS03995	COG0617	tRNA 3'-terminal CCA addition
FGM04_RS03995	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FGM04_RS04000	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGM04_RS04010	COG2925	Exonuclease
FGM04_RS04020	COG3345	alpha-galactosidase
FGM04_RS04025	COG1380	Effector of murein hydrolase LrgA
FGM04_RS04030	COG1346	cytolysis
FGM04_RS04035	COG0295	cytidine deaminase activity
FGM04_RS04045	COG3033	Beta-eliminating lyase
FGM04_RS04055	COG3046	protein related to deoxyribodipyrimidine photolyase
FGM04_RS04060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_RS04065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGM04_RS04090	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGM04_RS04110	COG3158	transport of potassium into the cell
FGM04_RS04115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGM04_RS04120	COG0651	ATP synthesis coupled electron transport
FGM04_RS04125	COG0650	Formate hydrogenlyase subunit 4
FGM04_RS04130	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FGM04_RS04130	COG3261	NADH dehydrogenase
FGM04_RS04135	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_RS04140	COG3260	NADH ubiquinone oxidoreductase 20
FGM04_RS04150	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FGM04_RS04160	COG1921	L-seryl-tRNASec selenium transferase activity
FGM04_RS04170	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FGM04_RS04175	COG0298	carbon dioxide binding
FGM04_RS04185	COG0309	Hydrogenase expression formation protein (HypE)
FGM04_RS04190	COG0375	protein maturation
FGM04_RS04195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FGM04_RS04200	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FGM04_RS04210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGM04_RS04215	COG0601	transmembrane transport
FGM04_RS04225	COG1773	rubredoxin
FGM04_RS04230	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FGM04_RS04235	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FGM04_RS04240	COG5557	Pfam Polysulphide reductase, NrfD
FGM04_RS04245	COG0437	4 iron, 4 sulfur cluster binding
FGM04_RS04250	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FGM04_RS04255	COG5001	Diguanylate cyclase
FGM04_RS04255	COG4251	negative regulation of phosphorylation
FGM04_RS04255	COG3706	GGDEF domain
FGM04_RS04255	COG2203	Gaf domain
FGM04_RS04260	COG0438	transferase activity, transferring glycosyl groups
FGM04_RS04265	COG0438	transferase activity, transferring glycosyl groups
FGM04_RS04285	COG0438	transferase activity, transferring glycosyl groups
FGM04_RS04365	COG0784	Response regulator, receiver
FGM04_RS04365	COG2205	protein histidine kinase activity
FGM04_RS04420	COG2003	Belongs to the UPF0758 family
FGM04_RS04450	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FGM04_RS04470	COG0730	response to heat
FGM04_RS04480	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_RS04490	COG1024	Enoyl-CoA hydratase
FGM04_RS04495	COG1024	Enoyl-CoA hydratase
FGM04_RS04500	COG1960	acyl-CoA dehydrogenase activity
FGM04_RS04505	COG1960	acyl-CoA dehydrogenase activity
FGM04_RS04510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGM04_RS04515	COG1024	Enoyl-CoA hydratase
FGM04_RS04545	COG1584	GPR1 FUN34 yaaH family protein
FGM04_RS04570	COG2983	Belongs to the UPF0260 family
FGM04_RS04575	COG1882	Formate acetyltransferase
FGM04_RS04580	COG2116	formate transmembrane transporter activity
FGM04_RS04585	COG1944	ATP diphosphatase activity
FGM04_RS04590	COG2723	6-phospho-beta-galactosidase activity
FGM04_RS04595	COG0583	DNA-binding transcription factor activity
FGM04_RS04605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGM04_RS04620	COG1335	isochorismatase
FGM04_RS04630	COG2271	Major facilitator Superfamily
FGM04_RS04635	COG0583	DNA-binding transcription factor activity
FGM04_RS04640	COG0583	DNA-binding transcription factor activity
FGM04_RS04645	COG2910	NAD(P)H-binding
FGM04_RS04680	COG0861	Integral membrane protein TerC family
FGM04_RS04685	COG2885	chlorophyll binding
FGM04_RS04690	COG2199	diguanylate cyclase activity
FGM04_RS04710	COG2154	pterin-4-alpha-carbinolamine dehydratase
FGM04_RS04720	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_RS04725	COG1177	transmembrane transport
FGM04_RS04730	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGM04_RS04735	COG3842	ATPase activity
FGM04_RS04740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FGM04_RS04745	COG0583	DNA-binding transcription factor activity
FGM04_RS04750	COG3768	UPF0283 membrane protein
FGM04_RS04755	COG3106	COG3106 Predicted ATPase
FGM04_RS04770	COG1842	Phage shock protein A
FGM04_RS04775	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FGM04_RS04785	COG4168	peptide transport system, permease
FGM04_RS04795	COG4172	Belongs to the ABC transporter superfamily
FGM04_RS04800	COG4172	Belongs to the ABC transporter superfamily
FGM04_RS04805	COG0326	Molecular chaperone. Has ATPase activity
FGM04_RS04810	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FGM04_RS04835	COG3039	Transposase
FGM04_RS04905	COG1435	thymidine kinase activity
FGM04_RS04910	COG1757	Na H antiporter
FGM04_RS04915	COG2916	Histone family protein nucleoid-structuring protein H-NS
FGM04_RS04920	COG2096	Adenosyltransferase
FGM04_RS04925	COG3530	Putative quorum-sensing-regulated virulence factor
FGM04_RS04930	COG0602	queuosine metabolic process
FGM04_RS04935	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FGM04_RS04955	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FGM04_RS04965	COG0776	regulation of translation
FGM04_RS04970	COG0539	negative regulation of cytoplasmic translation
FGM04_RS04975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FGM04_RS04980	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGM04_RS04995	COG2814	Major facilitator Superfamily
FGM04_RS05010	COG0778	Nitroreductase
FGM04_RS05015	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FGM04_RS05020	COG5001	Diguanylate cyclase
FGM04_RS05020	COG3300	MHYT domain
FGM04_RS05025	COG0583	DNA-binding transcription factor activity
FGM04_RS05030	COG3437	response regulator, receiver
FGM04_RS05055	COG4989	oxidoreductase activity
FGM04_RS05060	COG0724	RNA recognition motif
FGM04_RS05070	COG1126	abc transporter atp-binding protein
FGM04_RS05075	COG0765	amino acid transport
FGM04_RS05080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_RS05085	COG4597	amino acid ABC transporter
FGM04_RS05090	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FGM04_RS05100	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FGM04_RS05115	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGM04_RS05120	COG1360	Flagellar Motor Protein
FGM04_RS05125	COG4771	TonB-dependent receptor
FGM04_RS05130	COG1770	oligopeptidase
FGM04_RS05155	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_RS05160	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_RS05165	COG0649	NAD binding
FGM04_RS05165	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_RS05180	COG1034	ATP synthesis coupled electron transport
FGM04_RS05185	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FGM04_RS05190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_RS05195	COG0839	Belongs to the complex I subunit 6 family
FGM04_RS05200	COG0713	ATP synthesis coupled electron transport
FGM04_RS05210	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_RS05215	COG1007	ATP synthesis coupled electron transport
FGM04_RS05230	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGM04_RS05230	COG2199	diguanylate cyclase activity
FGM04_RS05235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGM04_RS05235	COG0047	phosphoribosylformylglycinamidine synthase activity
FGM04_RS05240	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FGM04_RS05250	COG1645	bacterial-type flagellum-dependent swarming motility
FGM04_RS05255	COG1160	GTP binding
FGM04_RS05260	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGM04_RS05265	COG2976	Protein conserved in bacteria
FGM04_RS05270	COG0124	histidyl-tRNA synthetase
FGM04_RS05275	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FGM04_RS05290	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FGM04_RS05295	COG0105	UTP biosynthetic process
FGM04_RS05310	COG0633	Ferredoxin
FGM04_RS05315	COG0443	Heat shock 70 kDa protein
FGM04_RS05320	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FGM04_RS05330	COG0822	iron-sulfur transferase activity
FGM04_RS05335	COG1104	cysteine desulfurase activity
FGM04_RS05355	COG3154	lipid carrier protein
FGM04_RS05360	COG0826	peptidase U32
FGM04_RS05365	COG0826	peptidase U32
FGM04_RS05380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGM04_RS05385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGM04_RS05390	COG1862	Preprotein translocase
FGM04_RS05395	COG0343	queuine tRNA-ribosyltransferase activity
FGM04_RS05400	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FGM04_RS05405	COG0517	IMP dehydrogenase activity
FGM04_RS05415	COG3634	alkyl hydroperoxide reductase activity
FGM04_RS05455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGM04_RS05455	COG0574	Belongs to the PEP-utilizing enzyme family
FGM04_RS05460	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FGM04_RS05490	COG0840	transmembrane signaling receptor activity
FGM04_RS05495	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGM04_RS05495	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGM04_RS05500	COG0509	glycine decarboxylation via glycine cleavage system
FGM04_RS05505	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGM04_RS05515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGM04_RS05520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGM04_RS05540	COG2814	Major facilitator Superfamily
FGM04_RS05545	COG0625	glutathione transferase activity
FGM04_RS05555	COG0483	inositol monophosphate 1-phosphatase activity
FGM04_RS05570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FGM04_RS05655	COG0656	L-ascorbic acid biosynthetic process
FGM04_RS05665	COG2814	Major facilitator Superfamily
FGM04_RS05685	COG3220	belongs to the UPF0276 family
FGM04_RS05705	COG1294	oxidase, subunit
FGM04_RS05715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGM04_RS05725	COG2979	Protein of unknown function (DUF533)
FGM04_RS05740	COG0583	DNA-binding transcription factor activity
FGM04_RS05745	COG2807	transmembrane transport
FGM04_RS05750	COG1187	pseudouridine synthase activity
FGM04_RS05765	COG0301	tRNA thio-modification
FGM04_RS05765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGM04_RS05780	COG4953	penicillin-binding protein 1C
FGM04_RS05785	COG2373	Large extracellular alpha-helical protein
FGM04_RS05795	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGM04_RS05800	COG3300	MHYT domain
FGM04_RS05800	COG5001	Diguanylate cyclase
FGM04_RS05805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGM04_RS05815	COG1252	NADH dehydrogenase
FGM04_RS05820	COG3150	esterase
FGM04_RS05825	COG2233	PERMEase
FGM04_RS05835	COG2354	Protein conserved in bacteria
FGM04_RS05845	COG0840	transmembrane signaling receptor activity
FGM04_RS05850	COG1301	dicarboxylic acid transport
FGM04_RS05865	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FGM04_RS05880	COG0537	adenosine 5'-monophosphoramidase activity
FGM04_RS05915	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGM04_RS05920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGM04_RS05930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGM04_RS05935	COG1605	Chorismate mutase
FGM04_RS05935	COG0287	Prephenate dehydrogenase
FGM04_RS05945	COG1199	ATP-dependent helicase activity
FGM04_RS05955	COG0123	including yeast histone deacetylase and acetoin utilization protein
FGM04_RS05960	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FGM04_RS05965	COG1785	Belongs to the alkaline phosphatase family
FGM04_RS05985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGM04_RS05990	COG2197	response regulator
FGM04_RS06000	COG2271	Major facilitator Superfamily
FGM04_RS06005	COG3706	GGDEF domain
FGM04_RS06010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_RS06015	COG0765	amino acid transport
FGM04_RS06020	COG1126	abc transporter atp-binding protein
FGM04_RS06035	COG0531	amino acid
FGM04_RS06050	COG1253	flavin adenine dinucleotide binding
FGM04_RS06055	COG0704	Plays a role in the regulation of phosphate uptake
FGM04_RS06060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FGM04_RS06065	COG0581	inorganic phosphate transmembrane transporter activity
FGM04_RS06070	COG0573	inorganic phosphate transmembrane transporter activity
FGM04_RS06075	COG0590	tRNA wobble adenosine to inosine editing
FGM04_RS06085	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FGM04_RS06105	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FGM04_RS06110	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FGM04_RS06115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FGM04_RS06120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FGM04_RS06145	COG2716	regulation of RNA biosynthetic process
FGM04_RS06150	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FGM04_RS06160	COG2239	Acts as a magnesium transporter
FGM04_RS06165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FGM04_RS06175	COG3951	Flagellar rod assembly protein muramidase FlgJ
FGM04_RS06175	COG1705	Flagellar rod assembly protein muramidase FlgJ
FGM04_RS06180	COG1706	bacterial-type flagellum-dependent cell motility
FGM04_RS06185	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FGM04_RS06195	COG4787	bacterial-type flagellum-dependent cell motility
FGM04_RS06205	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FGM04_RS06215	COG1815	bacterial-type flagellum-dependent cell motility
FGM04_RS06220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FGM04_RS06225	COG0835	chemotaxis
FGM04_RS06225	COG0784	Response regulator, receiver
FGM04_RS06230	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FGM04_RS06245	COG0622	Phosphoesterase
FGM04_RS06250	COG4166	transmembrane transport
FGM04_RS06260	COG1187	pseudouridine synthase activity
FGM04_RS06265	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGM04_RS06275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGM04_RS06280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGM04_RS06285	COG1882	Formate acetyltransferase
FGM04_RS06290	COG1349	DNA-binding transcription factor activity
FGM04_RS06295	COG4166	transmembrane transport
FGM04_RS06320	COG1278	Cold shock
FGM04_RS06345	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FGM04_RS06345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGM04_RS06350	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_RS06355	COG3433	isochorismatase activity
FGM04_RS06355	COG1535	isochorismatase
FGM04_RS06360	COG1021	2,3-dihydroxybenzoate-AMP ligase
FGM04_RS06365	COG1169	isochorismate synthase
FGM04_RS06370	COG4771	TonB-dependent receptor
FGM04_RS06375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGM04_RS06385	COG0741	lytic transglycosylase activity
FGM04_RS06395	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FGM04_RS06415	COG2911	Protein conserved in bacteria
FGM04_RS06420	COG0729	surface antigen
FGM04_RS06430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGM04_RS06440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGM04_RS06450	COG4134	Bacterial extracellular solute-binding protein
FGM04_RS06460	COG4136	ATPase activity
FGM04_RS06465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FGM04_RS06470	COG2951	lytic endotransglycosylase activity
FGM04_RS06475	COG0033	Phosphoglucomutase
FGM04_RS06480	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FGM04_RS06485	COG0596	Alpha beta hydrolase
FGM04_RS06500	COG0716	FMN binding
FGM04_RS06510	COG0735	belongs to the Fur family
FGM04_RS06515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGM04_RS06525	COG1263	PTS System
FGM04_RS06525	COG2190	(PTS) system
FGM04_RS06525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_RS06530	COG0363	glucosamine-6-phosphate deaminase activity
FGM04_RS06535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FGM04_RS06540	COG1940	carbohydrate kinase activity
FGM04_RS06540	COG1846	Transcriptional regulator
FGM04_RS06550	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGM04_RS06550	COG2199	diguanylate cyclase activity
FGM04_RS06555	COG3275	phosphorelay sensor kinase activity
FGM04_RS06560	COG3279	Response regulator of the LytR AlgR family
FGM04_RS06565	COG1966	Carbon starvation protein
FGM04_RS06575	COG1566	PFAM secretion protein HlyD family protein
FGM04_RS06580	COG1061	Type III restriction enzyme res subunit
FGM04_RS06585	COG2027	D-alanyl-D-alanine carboxypeptidase
FGM04_RS06590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FGM04_RS06595	COG3021	interspecies interaction between organisms
FGM04_RS06605	COG1607	acyl-coa hydrolase
FGM04_RS06610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGM04_RS06635	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FGM04_RS06635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FGM04_RS06635	COG1013	pyruvate-flavodoxin oxidoreductase activity
FGM04_RS06635	COG0674	pyruvate-flavodoxin oxidoreductase activity
FGM04_RS06650	COG0633	Ferredoxin
FGM04_RS06650	COG3217	Mosc domain protein beta barrel domain protein
FGM04_RS06650	COG3217	Mosc domain protein beta barrel domain protein
FGM04_RS06650	COG0633	Ferredoxin
FGM04_RS06655	COG0471	metal ion transport
FGM04_RS06665	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FGM04_RS06670	COG0791	NLP P60 protein
FGM04_RS06680	COG3118	belongs to the thioredoxin family
FGM04_RS06690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGM04_RS06695	COG0788	formyltetrahydrofolate deformylase activity
FGM04_RS06705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGM04_RS06720	COG0739	heme binding
FGM04_RS06720	COG0741	lytic transglycosylase activity
FGM04_RS06720	COG1196	nuclear chromosome segregation
FGM04_RS06725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGM04_RS06735	COG0436	Aminotransferase
FGM04_RS06760	COG0564	pseudouridine synthase activity
FGM04_RS06770	COG1454	alcohol dehydrogenase
FGM04_RS06775	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGM04_RS06780	COG0702	epimerase
FGM04_RS06790	COG0095	Lipoate-protein ligase
FGM04_RS06800	COG0577	efflux transmembrane transporter activity
FGM04_RS06800	COG1136	(ABC) transporter
FGM04_RS06805	COG1136	(ABC) transporter
FGM04_RS06805	COG0577	efflux transmembrane transporter activity
FGM04_RS06810	COG1136	(ABC) transporter
FGM04_RS06810	COG0577	efflux transmembrane transporter activity
FGM04_RS06830	COG2391	methyltransferase activity
FGM04_RS06850	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGM04_RS06860	COG1285	pathogenesis
FGM04_RS06890	COG0484	heat shock protein binding
FGM04_RS06895	COG0443	Heat shock 70 kDa protein
FGM04_RS06900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGM04_RS06905	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGM04_RS06910	COG0497	DNA recombination
FGM04_RS06915	COG1227	inorganic diphosphatase activity
FGM04_RS06920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_RS06925	COG0577	efflux transmembrane transporter activity
FGM04_RS06925	COG1136	(ABC) transporter
FGM04_RS06945	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGM04_RS06980	COG1091	dTDP-4-dehydrorhamnose reductase activity
FGM04_RS07005	COG0438	transferase activity, transferring glycosyl groups
FGM04_RS07030	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FGM04_RS07040	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FGM04_RS07050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGM04_RS07060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGM04_RS07065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_RS07070	COG1309	transcriptional regulator
FGM04_RS07085	COG1342	Belongs to the UPF0251 family
FGM04_RS07105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGM04_RS07120	COG1943	Transposase
FGM04_RS07135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FGM04_RS07140	COG0083	homoserine kinase activity
FGM04_RS07155	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FGM04_RS07160	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FGM04_RS07165	COG1946	Acyl-CoA thioesterase
FGM04_RS07175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FGM04_RS07185	COG0009	L-threonylcarbamoyladenylate synthase
FGM04_RS07195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGM04_RS07200	COG0512	Glutamine amidotransferase of anthranilate synthase
FGM04_RS07200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGM04_RS07205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGM04_RS07210	COG0134	indole-3-glycerol-phosphate synthase activity
FGM04_RS07210	COG0135	phosphoribosylanthranilate isomerase activity
FGM04_RS07215	COG0133	tryptophan synthase activity
FGM04_RS07220	COG0159	tryptophan synthase activity
FGM04_RS07225	COG1196	nuclear chromosome segregation
FGM04_RS07230	COG1988	membrane-bound metal-dependent
FGM04_RS07250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGM04_RS07260	COG0798	PFAM Bile acid sodium symporter
FGM04_RS07290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FGM04_RS07300	COG0745	RESPONSE REGULATOR receiver
FGM04_RS07320	COG4988	ABC transporter
FGM04_RS07325	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FGM04_RS07345	COG1720	tRNA m6t6A37 methyltransferase activity
FGM04_RS07350	COG3038	cytochrome b561
FGM04_RS07370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGM04_RS07370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGM04_RS07380	COG1882	Formate acetyltransferase
FGM04_RS07385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGM04_RS07395	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FGM04_RS07400	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FGM04_RS07410	COG2853	Lipoprotein
FGM04_RS07420	COG3088	subunit of a heme lyase
FGM04_RS07420	COG4235	cytochrome complex assembly
FGM04_RS07425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGM04_RS07430	COG1138	Cytochrome C-type biogenesis protein
FGM04_RS07435	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FGM04_RS07440	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGM04_RS07445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGM04_RS07450	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGM04_RS07465	COG0835	chemotaxis
FGM04_RS07475	COG1192	Involved in chromosome partitioning
FGM04_RS07485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGM04_RS07495	COG0643	Histidine kinase
FGM04_RS07495	COG2198	Histidine kinase
FGM04_RS07495	COG0784	Response regulator, receiver
FGM04_RS07500	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FGM04_RS07525	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FGM04_RS07535	COG1684	flagellar biosynthetic protein fliR
FGM04_RS07590	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FGM04_RS07600	COG1677	Flagellar hook-basal body complex protein FliE
FGM04_RS07620	COG0469	pyruvate kinase activity
FGM04_RS07625	COG1737	Transcriptional regulator
FGM04_RS07630	COG0837	glucose binding
FGM04_RS07660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_RS07675	COG0281	malic enzyme
FGM04_RS07685	COG0534	Mate efflux family protein
FGM04_RS07700	COG2233	PERMEase
FGM04_RS07705	COG0095	Lipoate-protein ligase
FGM04_RS07710	COG1115	amino acid carrier protein
FGM04_RS07715	COG0019	diaminopimelate decarboxylase activity
FGM04_RS07725	COG0678	peroxiredoxin activity
FGM04_RS07750	COG0545	Peptidyl-prolyl cis-trans isomerase
FGM04_RS07755	COG3142	Participates in the control of copper homeostasis
FGM04_RS07780	COG5002	protein histidine kinase activity
FGM04_RS07785	COG0745	RESPONSE REGULATOR receiver
FGM04_RS07790	COG0346	lactoylglutathione lyase activity
FGM04_RS07795	COG3284	Transcriptional regulator
FGM04_RS07810	COG0697	spore germination
FGM04_RS07820	COG3290	protein histidine kinase activity
FGM04_RS07825	COG0281	malic enzyme
FGM04_RS07835	COG1846	Transcriptional regulator
FGM04_RS07870	COG0602	queuosine metabolic process
FGM04_RS07875	COG1328	CTP reductase activity
FGM04_RS07885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGM04_RS07890	COG3115	cell septum assembly
FGM04_RS07895	COG1196	nuclear chromosome segregation
FGM04_RS07905	COG2860	membrane
FGM04_RS07915	COG3108	Peptidase M15
FGM04_RS07920	COG2989	Protein conserved in bacteria
FGM04_RS07935	COG0463	Glycosyl transferase, family 2
FGM04_RS07950	COG0366	Alpha amylase catalytic
FGM04_RS07985	COG2203	Gaf domain
FGM04_RS07985	COG2199	diguanylate cyclase activity
FGM04_RS07995	COG3590	peptidase
FGM04_RS08005	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FGM04_RS08010	COG1982	Orn Lys Arg decarboxylase major
FGM04_RS08015	COG0531	amino acid
FGM04_RS08020	COG3710	Transcriptional regulator
FGM04_RS08025	COG0531	amino acid
FGM04_RS08045	COG0814	amino acid
FGM04_RS08075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGM04_RS08080	COG0739	heme binding
FGM04_RS08085	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FGM04_RS08095	COG0251	oxidation-reduction process
FGM04_RS08110	COG0583	DNA-binding transcription factor activity
FGM04_RS08115	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_RS08115	COG3321	synthase
FGM04_RS08115	COG0604	alcohol dehydrogenase
FGM04_RS08130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FGM04_RS08140	COG3091	SprT-like family
FGM04_RS08150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FGM04_RS08155	COG0189	ligase activity
FGM04_RS08160	COG1678	Uncharacterized ACR, COG1678
FGM04_RS08165	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FGM04_RS08170	COG3104	oligopeptide transport
FGM04_RS08185	COG0714	Associated with various cellular activities
FGM04_RS08200	COG1115	amino acid carrier protein
FGM04_RS08205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGM04_RS08215	COG0825	malonyl-CoA metabolic process
FGM04_RS08225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGM04_RS08230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGM04_RS08235	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGM04_RS08240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGM04_RS08245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGM04_RS08260	COG0750	zinc metalloprotease
FGM04_RS08265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FGM04_RS08270	COG0575	Belongs to the CDS family
FGM04_RS08275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FGM04_RS08280	COG0233	cytoplasmic translational termination
FGM04_RS08285	COG0528	UMP kinase activity
FGM04_RS08290	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FGM04_RS08295	COG0052	Belongs to the universal ribosomal protein uS2 family
FGM04_RS08300	COG0024	Methionine aminopeptidase
FGM04_RS08310	COG2171	N-acyltransferase activity
FGM04_RS08320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_RS08320	COG1263	PTS System
FGM04_RS08340	COG0564	pseudouridine synthase activity
FGM04_RS08345	COG3098	single-species biofilm formation
FGM04_RS08370	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FGM04_RS08380	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FGM04_RS08380	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FGM04_RS08395	COG1611	Belongs to the LOG family
FGM04_RS08400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGM04_RS08405	COG0473	3-isopropylmalate dehydrogenase activity
FGM04_RS08415	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FGM04_RS08420	COG2363	Small membrane protein
FGM04_RS08430	COG0583	DNA-binding transcription factor activity
FGM04_RS08435	COG0840	transmembrane signaling receptor activity
FGM04_RS08440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGM04_RS08455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FGM04_RS08460	COG1666	GTP binding
FGM04_RS08470	COG2211	Major facilitator Superfamily
FGM04_RS08475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGM04_RS08485	COG2813	Specifically methylates the guanine in position
FGM04_RS08490	COG0271	Belongs to the BolA IbaG family
FGM04_RS08495	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FGM04_RS08500	COG1805	sodium ion transport
FGM04_RS08505	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FGM04_RS08510	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FGM04_RS08515	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FGM04_RS08520	COG2871	sodium ion transport
FGM04_RS08525	COG1477	protein flavinylation
FGM04_RS08555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGM04_RS08570	COG0300	oxidoreductase activity
FGM04_RS08580	COG0415	Belongs to the DNA photolyase family
FGM04_RS08585	COG0789	Transcriptional regulator
FGM04_RS08590	COG3272	Protein of unknown function (DUF1722)
FGM04_RS08620	COG1605	Chorismate mutase
FGM04_RS08620	COG0077	Prephenate dehydratase
FGM04_RS08660	COG0300	oxidoreductase activity
FGM04_RS08685	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FGM04_RS08725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGM04_RS08730	COG0826	peptidase U32
FGM04_RS08735	COG1280	lysine exporter protein (LysE YggA)
FGM04_RS08745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGM04_RS08755	COG0745	RESPONSE REGULATOR receiver
FGM04_RS08765	COG0643	Histidine kinase
FGM04_RS08765	COG2198	Histidine kinase
FGM04_RS08775	COG0835	chemotaxis
FGM04_RS08780	COG0840	transmembrane signaling receptor activity
FGM04_RS08790	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FGM04_RS08795	COG2201	protein-glutamate methylesterase activity
FGM04_RS08800	COG1185	polyribonucleotide nucleotidyltransferase activity
FGM04_RS08805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FGM04_RS08810	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FGM04_RS08815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FGM04_RS08820	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FGM04_RS08825	COG0195	Participates in both transcription termination and antitermination
FGM04_RS08830	COG0779	Required for maturation of 30S ribosomal subunits
FGM04_RS08845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FGM04_RS08850	COG0149	triose-phosphate isomerase activity
FGM04_RS08855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGM04_RS08860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FGM04_RS08870	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FGM04_RS08875	COG1534	Rna-binding protein
FGM04_RS08890	COG1360	Flagellar Motor Protein
FGM04_RS08895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGM04_RS08900	COG1722	exodeoxyribonuclease VII activity
FGM04_RS08905	COG0142	geranyltranstransferase activity
FGM04_RS08910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FGM04_RS08925	COG4145	pantothenate transmembrane transporter activity
FGM04_RS08930	COG2190	(PTS) system
FGM04_RS08930	COG1263	PTS System
FGM04_RS08930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_RS08935	COG0583	DNA-binding transcription factor activity
FGM04_RS08940	COG0604	alcohol dehydrogenase
FGM04_RS08945	COG2264	protein methyltransferase activity
FGM04_RS08950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGM04_RS08955	COG0110	maltose O-acetyltransferase activity
FGM04_RS08960	COG0778	Nitroreductase
FGM04_RS08965	COG1902	pentaerythritol trinitrate reductase activity
FGM04_RS08965	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGM04_RS08970	COG0616	signal peptide processing
FGM04_RS08995	COG0748	coenzyme F420 binding
FGM04_RS09000	COG3721	Heme iron utilization protein
FGM04_RS09010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGM04_RS09025	COG3275	phosphorelay sensor kinase activity
FGM04_RS09030	COG3279	Response regulator of the LytR AlgR family
FGM04_RS09035	COG1966	Carbon starvation protein
FGM04_RS09040	COG3340	Belongs to the peptidase S51 family
FGM04_RS09050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGM04_RS09065	COG0737	Belongs to the 5'-nucleotidase family
FGM04_RS09085	COG2204	response regulator
FGM04_RS09090	COG0545	Peptidyl-prolyl cis-trans isomerase
FGM04_RS09100	COG2900	Belongs to the SlyX family
FGM04_RS09115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGM04_RS09120	COG2313	pseudouridylate synthase activity
FGM04_RS09150	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FGM04_RS09245	COG2985	domain, Protein
FGM04_RS09245	COG0569	domain protein
FGM04_RS09250	COG1272	protein, Hemolysin III
FGM04_RS09255	COG0076	glutamate decarboxylase activity
FGM04_RS09260	COG2917	probably involved in intracellular septation
FGM04_RS09265	COG2350	Protein conserved in bacteria
FGM04_RS09275	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FGM04_RS09280	COG1381	Involved in DNA repair and RecF pathway recombination
FGM04_RS09295	COG0681	Belongs to the peptidase S26 family
FGM04_RS09300	COG0481	GTPase activity
FGM04_RS09310	COG3026	antisigma factor binding
FGM04_RS09315	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FGM04_RS09320	COG1595	DNA-templated transcription, initiation
FGM04_RS09325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FGM04_RS09335	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FGM04_RS09340	COG0354	folic acid binding
FGM04_RS09385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_RS09390	COG0191	fructose-bisphosphate aldolase activity
FGM04_RS09395	COG0126	phosphoglycerate kinase activity
FGM04_RS09400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FGM04_RS09405	COG1940	carbohydrate kinase activity
FGM04_RS09410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FGM04_RS09415	COG2816	NAD+ diphosphatase activity
FGM04_RS09425	COG4991	sh3 domain protein
FGM04_RS09430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGM04_RS09440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGM04_RS09445	COG0840	transmembrane signaling receptor activity
FGM04_RS09455	COG1278	Cold shock
FGM04_RS09495	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FGM04_RS09500	COG1162	GTPase activity
FGM04_RS09505	COG0688	phosphatidylethanolamine metabolic process
FGM04_RS09510	COG4628	conserved protein (DUF2132)
FGM04_RS09525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FGM04_RS09540	COG1073	alpha beta
FGM04_RS09545	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FGM04_RS09555	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGM04_RS09560	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FGM04_RS09565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FGM04_RS09570	COG3178	'Phosphotransferase
FGM04_RS09575	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FGM04_RS09580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGM04_RS09585	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FGM04_RS09590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGM04_RS09595	COG2967	ApaG domain
FGM04_RS09600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FGM04_RS09615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGM04_RS09625	COG3314	Sporulation integral membrane protein YlbJ
FGM04_RS09630	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGM04_RS09635	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FGM04_RS09640	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FGM04_RS09645	COG0142	geranyltranstransferase activity
FGM04_RS09650	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FGM04_RS09655	COG0330	HflC and HflK could
FGM04_RS09660	COG0330	HflC and HflK could
FGM04_RS09665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FGM04_RS09670	COG1923	regulation of RNA biosynthetic process
FGM04_RS09675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGM04_RS09680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGM04_RS09685	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGM04_RS09695	COG0802	atpase or kinase
FGM04_RS09700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FGM04_RS09700	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FGM04_RS09720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGM04_RS09725	COG2011	ABC-type metal ion transport system permease component
FGM04_RS09730	COG1464	Belongs to the NlpA lipoprotein family
FGM04_RS09765	COG5002	protein histidine kinase activity
FGM04_RS09765	COG2198	Histidine kinase
FGM04_RS09765	COG0784	Response regulator, receiver
FGM04_RS09800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FGM04_RS09805	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FGM04_RS09810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGM04_RS09815	COG2716	regulation of RNA biosynthetic process
FGM04_RS09820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FGM04_RS09825	COG3013	Belongs to the UPF0304 family
FGM04_RS09835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGM04_RS09840	COG0857	belongs to the CobB CobQ family
FGM04_RS09840	COG0280	phosphate acetyltransferase
FGM04_RS09845	COG1555	photosystem II stabilization
FGM04_RS09850	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGM04_RS09855	COG3104	oligopeptide transport
FGM04_RS09860	COG0745	RESPONSE REGULATOR receiver
FGM04_RS09890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_RS09905	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FGM04_RS09940	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FGM04_RS09950	COG1401	restriction endodeoxyribonuclease activity
FGM04_RS09955	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FGM04_RS09965	COG0732	type I restriction modification DNA specificity domain
FGM04_RS09970	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FGM04_RS09975	COG1715	Restriction endonuclease
FGM04_RS10015	COG2003	Belongs to the UPF0758 family
FGM04_RS10060	COG3311	Transcriptional regulator
FGM04_RS10105	COG0440	acetolactate synthase activity
FGM04_RS10110	COG0028	Belongs to the TPP enzyme family
FGM04_RS10135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGM04_RS10140	COG0473	3-isopropylmalate dehydrogenase activity
FGM04_RS10145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FGM04_RS10150	COG0066	3-isopropylmalate dehydratase activity
FGM04_RS10165	COG4143	(ABC) transporter
FGM04_RS10175	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FGM04_RS10180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FGM04_RS10230	COG0459	protein refolding
FGM04_RS10235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGM04_RS10240	COG0534	Mate efflux family protein
FGM04_RS10245	COG3030	protein affecting phage T7 exclusion by the F plasmid
FGM04_RS10250	COG1027	Aspartate ammonia-lyase
FGM04_RS10255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FGM04_RS10260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGM04_RS10265	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FGM04_RS10270	COG1610	YqeY-like protein
FGM04_RS10275	COG0358	DNA primase activity
FGM04_RS10280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGM04_RS10300	COG0151	Belongs to the GarS family
FGM04_RS10305	COG0138	bifunctional purine biosynthesis protein purh
FGM04_RS10315	COG3036	rescue of stalled ribosome
FGM04_RS10320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGM04_RS10325	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGM04_RS10335	COG0673	inositol 2-dehydrogenase activity
FGM04_RS10345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGM04_RS10350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGM04_RS10360	COG0583	DNA-binding transcription factor activity
FGM04_RS10365	COG0477	Major facilitator Superfamily
FGM04_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_RS10390	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FGM04_RS10415	COG1022	Amp-dependent synthetase and ligase
FGM04_RS10420	COG2918	glutathione biosynthetic process
FGM04_RS10425	COG0612	Peptidase, M16
FGM04_RS10430	COG1238	metal cluster binding
FGM04_RS10435	COG1064	alcohol dehydrogenase
FGM04_RS10460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGM04_RS10465	COG0359	binds to the 23S rRNA
FGM04_RS10470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGM04_RS10475	COG0360	Binds together with S18 to 16S ribosomal RNA
FGM04_RS10480	COG1914	H( )-stimulated, divalent metal cation uptake system
FGM04_RS10485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGM04_RS10495	COG0776	regulation of translation
FGM04_RS10510	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FGM04_RS10525	COG0560	Phosphoserine phosphatase
FGM04_RS10535	COG0813	purine-nucleoside phosphorylase activity
FGM04_RS10540	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FGM04_RS10545	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FGM04_RS10550	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FGM04_RS10560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGM04_RS10565	COG0084	hydrolase, TatD family'
FGM04_RS10570	COG2165	general secretion pathway protein
FGM04_RS10575	COG1854	S-ribosylhomocysteine lyase activity
FGM04_RS10590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGM04_RS10590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FGM04_RS10635	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FGM04_RS10640	COG1047	Peptidyl-prolyl cis-trans
FGM04_RS10645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FGM04_RS10650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FGM04_RS10655	COG0196	riboflavin kinase activity
FGM04_RS10660	COG0728	peptidoglycan biosynthetic process
FGM04_RS10665	COG0268	Binds directly to 16S ribosomal RNA
FGM04_RS10670	COG0640	Transcriptional regulator
FGM04_RS10675	COG0583	DNA-binding transcription factor activity
FGM04_RS10685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGM04_RS10710	COG0347	Belongs to the P(II) protein family
FGM04_RS10730	COG3022	response to hydroperoxide
FGM04_RS10745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FGM04_RS10750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FGM04_RS10755	COG0762	integral membrane protein
FGM04_RS10760	COG1872	DUF167
FGM04_RS10770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGM04_RS10775	COG0583	DNA-binding transcription factor activity
FGM04_RS10790	COG1929	Belongs to the glycerate kinase type-1 family
FGM04_RS10795	COG2610	gluconate transmembrane transporter activity
FGM04_RS10800	COG3835	regulator
FGM04_RS10805	COG3112	Uncharacterised protein family (UPF0231)
FGM04_RS10825	COG3568	Endonuclease Exonuclease Phosphatase
FGM04_RS10835	COG0513	Belongs to the DEAD box helicase family
FGM04_RS10860	COG0617	tRNA 3'-terminal CCA addition
FGM04_RS10865	COG1194	a g-specific adenine glycosylase
FGM04_RS10870	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FGM04_RS10880	COG3111	PFAM Bacterial OB fold (BOF) protein
FGM04_RS10885	COG3240	lipase activity
FGM04_RS10895	COG3706	GGDEF domain
FGM04_RS10900	COG0557	exoribonuclease II activity
FGM04_RS10905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGM04_RS10915	COG2153	protein acetylation
FGM04_RS10920	COG0513	Belongs to the DEAD box helicase family
FGM04_RS10925	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FGM04_RS10950	COG0735	belongs to the Fur family
FGM04_RS10955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGM04_RS10960	COG0840	transmembrane signaling receptor activity
FGM04_RS10970	COG4166	transmembrane transport
FGM04_RS10980	COG0110	maltose O-acetyltransferase activity
FGM04_RS10990	COG1024	Enoyl-CoA hydratase
FGM04_RS11005	COG4221	oxidoreductase activity
FGM04_RS11010	COG0442	prolyl-tRNA aminoacylation
FGM04_RS11015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGM04_RS11020	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FGM04_RS11025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FGM04_RS11035	COG1051	belongs to the nudix hydrolase family
FGM04_RS11040	COG3066	DNA modification
FGM04_RS11050	COG0335	large ribosomal subunit rRNA binding
FGM04_RS11055	COG0336	Belongs to the RNA methyltransferase TrmD family
FGM04_RS11060	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FGM04_RS11065	COG0228	four-way junction DNA binding
FGM04_RS11070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FGM04_RS11075	COG4137	Cytochrome C assembly protein
FGM04_RS11080	COG4536	flavin adenine dinucleotide binding
FGM04_RS11090	COG1017	nitric oxide dioxygenase activity
FGM04_RS11090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGM04_RS11095	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FGM04_RS11100	COG0039	L-malate dehydrogenase activity
FGM04_RS11105	COG4160	amino acid transport
FGM04_RS11110	COG4215	(ABC) transporter
FGM04_RS11115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_RS11120	COG1126	abc transporter atp-binding protein
FGM04_RS11125	COG1438	arginine binding
FGM04_RS11130	COG2837	iron assimilation
FGM04_RS11135	COG3842	ATPase activity
FGM04_RS11145	COG1840	ABC-type Fe3 transport system, periplasmic component
FGM04_RS11160	COG1448	Aminotransferase
FGM04_RS11175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGM04_RS11180	COG1328	CTP reductase activity
FGM04_RS11205	COG0543	2 iron, 2 sulfur cluster binding
FGM04_RS11205	COG0633	Ferredoxin
FGM04_RS11220	COG0840	transmembrane signaling receptor activity
FGM04_RS11225	COG3397	chitin binding
FGM04_RS11230	COG0583	DNA-binding transcription factor activity
FGM04_RS11235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FGM04_RS11240	COG4208	sulfate ABC transporter
FGM04_RS11245	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FGM04_RS11255	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FGM04_RS11260	COG3174	membrane
FGM04_RS11265	COG0110	maltose O-acetyltransferase activity
FGM04_RS11280	COG1011	Hydrolase
FGM04_RS11285	COG0494	nUDIX hydrolase
FGM04_RS11290	COG1218	3'(2'),5'-bisphosphate nucleotidase
FGM04_RS11300	COG0814	amino acid
FGM04_RS11305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGM04_RS11320	COG0626	cystathionine gamma-synthase activity
FGM04_RS11325	COG0527	aspartate kinase activity
FGM04_RS11325	COG0460	homoserine dehydrogenase
FGM04_RS11330	COG0306	phosphate transporter
FGM04_RS11335	COG1392	Phosphate transport regulator
FGM04_RS11345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGM04_RS11350	COG2813	Specifically methylates the guanine in position
FGM04_RS11355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FGM04_RS11360	COG0297	glycogen (starch) synthase activity
FGM04_RS11400	COG1757	Na H antiporter
FGM04_RS11405	COG0316	Belongs to the HesB IscA family
FGM04_RS11415	COG0038	chloride channel
FGM04_RS11420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FGM04_RS11435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FGM04_RS11435	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGM04_RS11465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGM04_RS11470	COG0564	pseudouridine synthase activity
FGM04_RS11480	COG0110	maltose O-acetyltransferase activity
FGM04_RS11485	COG0366	Alpha amylase catalytic
FGM04_RS11490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_RS11490	COG1263	PTS System
FGM04_RS11495	COG1609	Transcriptional regulator
FGM04_RS11510	COG0252	asparaginase activity
FGM04_RS11515	COG1253	flavin adenine dinucleotide binding
FGM04_RS11520	COG0586	Pfam SNARE associated Golgi protein
FGM04_RS11525	COG1686	Belongs to the peptidase S11 family
FGM04_RS11560	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FGM04_RS11565	COG0527	aspartate kinase activity
FGM04_RS11570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGM04_RS11580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FGM04_RS11585	COG1546	Belongs to the CinA family
FGM04_RS11590	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FGM04_RS11595	COG4667	esterase of the alpha-beta hydrolase superfamily
FGM04_RS11605	COG1346	cytolysis
FGM04_RS11610	COG1380	Effector of murein hydrolase LrgA
FGM04_RS11615	COG0583	DNA-binding transcription factor activity
FGM04_RS11625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FGM04_RS11640	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FGM04_RS11645	COG2022	thiamine diphosphate biosynthetic process
FGM04_RS11655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FGM04_RS11660	COG0352	thiamine-phosphate diphosphorylase activity
FGM04_RS11665	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FGM04_RS11685	COG0745	RESPONSE REGULATOR receiver
FGM04_RS11690	COG0642	Histidine kinase
FGM04_RS11695	COG0189	ligase activity
FGM04_RS11740	COG0477	Major facilitator Superfamily
FGM04_RS11755	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FGM04_RS11760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_RS11760	COG1263	PTS System
FGM04_RS11765	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FGM04_RS11770	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FGM04_RS11780	COG0312	modulator of DNA gyrase
FGM04_RS11785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGM04_RS11800	COG3164	Protein of unknown function
FGM04_RS11805	COG1530	ribonuclease E activity
FGM04_RS11810	COG0424	maF-like protein
FGM04_RS11815	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FGM04_RS11820	COG1792	Involved in formation and maintenance of cell shape
FGM04_RS11825	COG1077	Cell shape determining protein MreB Mrl
FGM04_RS11850	COG4968	Prepilin-type N-terminal cleavage methylation domain
FGM04_RS11855	COG2165	general secretion pathway protein
FGM04_RS11870	COG1459	type II secretion system
FGM04_RS11875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGM04_RS11920	COG2199	diguanylate cyclase activity
FGM04_RS11920	COG2200	EAL domain
FGM04_RS11925	COG2200	EAL domain
FGM04_RS11930	COG0387	Pfam Sodium calcium exchanger
FGM04_RS11935	COG2986	histidine ammonia-lyase
FGM04_RS11940	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FGM04_RS11945	COG0010	Belongs to the arginase family
FGM04_RS11950	COG1228	amidohydrolase
FGM04_RS11955	COG2188	Transcriptional regulator
FGM04_RS11960	COG0288	reversible hydration of carbon dioxide
FGM04_RS11970	COG2177	Part of the ABC transporter FtsEX involved in
FGM04_RS11975	COG2884	Cell division ATP-binding protein ftsE
FGM04_RS11980	COG0552	protein localization to endoplasmic reticulum
FGM04_RS11985	COG0742	ribosomal rna small subunit methyltransferase
FGM04_RS12010	COG2249	NAD(P)H dehydrogenase (quinone) activity
FGM04_RS12015	COG0583	DNA-binding transcription factor activity
FGM04_RS12020	COG4221	oxidoreductase activity
FGM04_RS12035	COG1770	oligopeptidase
FGM04_RS12050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGM04_RS12055	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FGM04_RS12065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGM04_RS12075	COG2095	MarC family integral membrane protein
FGM04_RS12085	COG1301	dicarboxylic acid transport
FGM04_RS12110	COG3714	YhhN family
FGM04_RS12165	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FGM04_RS12170	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGM04_RS12175	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGM04_RS12180	COG0049	tRNA binding
FGM04_RS12185	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FGM04_RS12190	COG2168	tRNA wobble position uridine thiolation
FGM04_RS12195	COG2923	Belongs to the DsrF TusC family
FGM04_RS12200	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FGM04_RS12210	COG2964	Protein conserved in bacteria
FGM04_RS12215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGM04_RS12220	COG0085	RNA polymerase activity
FGM04_RS12225	COG0222	ribosome binding
FGM04_RS12230	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FGM04_RS12235	COG0081	regulation of translation
FGM04_RS12240	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FGM04_RS12245	COG0250	Participates in transcription elongation, termination and antitermination
FGM04_RS12260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGM04_RS12285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FGM04_RS12290	COG0569	domain protein
FGM04_RS12295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGM04_RS12325	COG4191	Histidine kinase
FGM04_RS12325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_RS12330	COG3005	denitrification pathway
FGM04_RS12335	COG0243	molybdopterin cofactor binding
FGM04_RS12385	COG2204	response regulator
FGM04_RS12395	COG2205	protein histidine kinase activity
FGM04_RS12410	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_RS12415	COG0516	GMP reductase activity
FGM04_RS12415	COG0517	IMP dehydrogenase activity
FGM04_RS12420	COG5413	integral membrane protein
FGM04_RS12430	COG1522	sequence-specific DNA binding
FGM04_RS12435	COG2502	aspartate--ammonia ligase
FGM04_RS12440	COG0542	response to heat
FGM04_RS12450	COG0564	pseudouridine synthase activity
FGM04_RS12455	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGM04_RS12460	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGM04_RS12470	COG3681	Belongs to the UPF0597 family
FGM04_RS12475	COG2964	Protein conserved in bacteria
FGM04_RS12485	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FGM04_RS12490	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FGM04_RS12495	COG1979	alcohol dehydrogenase
FGM04_RS12500	COG2207	Transcriptional regulator
FGM04_RS12505	COG3040	lipid binding
FGM04_RS12520	COG0583	DNA-binding transcription factor activity
FGM04_RS12540	COG0540	Belongs to the ATCase OTCase family
FGM04_RS12545	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FGM04_RS12550	COG1438	arginine binding
FGM04_RS12555	COG1288	antiporter activity
FGM04_RS12560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGM04_RS12585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGM04_RS12595	COG3078	GTPase activator activity
FGM04_RS12605	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FGM04_RS12615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGM04_RS12620	COG0408	coproporphyrinogen oxidase activity
FGM04_RS12625	COG0009	L-threonylcarbamoyladenylate synthase
FGM04_RS12635	COG0551	DNA topoisomerase type I activity
FGM04_RS12640	COG2922	Belongs to the Smg family
FGM04_RS12645	COG0758	DNA mediated transformation
FGM04_RS12650	COG1652	LysM domain
FGM04_RS12655	COG0242	peptide deformylase activity
FGM04_RS12660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGM04_RS12665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGM04_RS12665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGM04_RS12670	COG0569	domain protein
FGM04_RS12675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGM04_RS12680	COG1217	gtp-binding protein TYPA
FGM04_RS12685	COG0174	glutamine synthetase
FGM04_RS12700	COG2204	response regulator
FGM04_RS12705	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FGM04_RS12710	COG1322	Protein conserved in bacteria
FGM04_RS12730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGM04_RS12735	COG0583	DNA-binding transcription factor activity
FGM04_RS12740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FGM04_RS12740	COG0519	Catalyzes the synthesis of GMP from XMP
FGM04_RS12750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FGM04_RS12755	COG1396	sequence-specific DNA binding
FGM04_RS12760	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_RS12770	COG2962	Rard protein
FGM04_RS12775	COG0840	transmembrane signaling receptor activity
FGM04_RS12780	COG2391	methyltransferase activity
FGM04_RS12795	COG0129	dihydroxy-acid dehydratase activity
FGM04_RS12805	COG3978	acetolactate synthase activity
FGM04_RS12820	COG0606	chelatase, subunit chli
FGM04_RS12825	COG0204	Acyl-transferase
FGM04_RS12830	COG0204	Acyl-transferase
FGM04_RS12835	COG1683	Conserved Protein
FGM04_RS12845	COG1335	isochorismatase
FGM04_RS12860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FGM04_RS12865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FGM04_RS12875	COG3084	Protein conserved in bacteria
FGM04_RS12880	COG2203	Gaf domain
FGM04_RS12880	COG4251	negative regulation of phosphorylation
FGM04_RS12880	COG3706	GGDEF domain
FGM04_RS12880	COG5001	Diguanylate cyclase
FGM04_RS12895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGM04_RS12900	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FGM04_RS12905	COG1561	YicC-like family, N-terminal region
FGM04_RS12950	COG3550	peptidyl-serine autophosphorylation
FGM04_RS12970	COG0583	DNA-binding transcription factor activity
FGM04_RS12995	COG0385	Bile acid
FGM04_RS13000	COG0531	amino acid
FGM04_RS13005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGM04_RS13010	COG0531	amino acid
FGM04_RS13015	COG2731	YhcH YjgK YiaL family protein
FGM04_RS13020	COG3250	beta-galactosidase activity
FGM04_RS13025	COG1609	Transcriptional regulator
FGM04_RS13060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FGM04_RS13065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGM04_RS13065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGM04_RS13070	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FGM04_RS13075	COG3074	FtsZ-dependent cytokinesis
FGM04_RS13085	COG1045	serine acetyltransferase
FGM04_RS13095	COG0745	RESPONSE REGULATOR receiver
FGM04_RS13100	COG2205	protein histidine kinase activity
FGM04_RS13105	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FGM04_RS13110	COG0534	Mate efflux family protein
FGM04_RS13125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FGM04_RS13130	COG2937	Belongs to the GPAT DAPAT family
FGM04_RS13135	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FGM04_RS13140	COG3161	chorismate lyase activity
FGM04_RS13165	COG0604	alcohol dehydrogenase
FGM04_RS13170	COG1519	Transferase
FGM04_RS13175	COG0859	PFAM glycosyl transferase family 9
FGM04_RS13180	COG0463	Glycosyl transferase, family 2
FGM04_RS13185	COG0859	PFAM glycosyl transferase family 9
FGM04_RS13190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FGM04_RS13195	COG2990	Protein conserved in bacteria
FGM04_RS13200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGM04_RS13210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGM04_RS13215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGM04_RS13220	COG2003	Belongs to the UPF0758 family
FGM04_RS13225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FGM04_RS13230	COG0756	dUTP diphosphatase activity
FGM04_RS13235	COG1309	transcriptional regulator
FGM04_RS13240	COG0668	transmembrane transport
FGM04_RS13245	COG0166	Belongs to the GPI family
FGM04_RS13250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FGM04_RS13270	COG1042	CoA-binding domain protein
FGM04_RS13270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGM04_RS13270	COG0045	succinate-CoA ligase (ADP-forming) activity
FGM04_RS13300	COG2801	Transposase and inactivated derivatives
FGM04_RS13305	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FGM04_RS13310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGM04_RS13315	COG1739	Uncharacterized protein family UPF0029
FGM04_RS13320	COG0006	proline dipeptidase activity
FGM04_RS13325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGM04_RS13330	COG1024	Enoyl-CoA hydratase
FGM04_RS13330	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGM04_RS13335	COG0183	Belongs to the thiolase family
FGM04_RS13360	COG0425	Belongs to the sulfur carrier protein TusA family
FGM04_RS13365	COG0251	oxidation-reduction process
FGM04_RS13370	COG2885	chlorophyll binding
FGM04_RS13375	COG2818	Glycosylase
FGM04_RS13380	COG0752	glycyl-tRNA synthetase alpha subunit
FGM04_RS13385	COG0751	glycine-tRNA ligase activity
FGM04_RS13390	COG2131	deaminase
FGM04_RS13400	COG2199	diguanylate cyclase activity
FGM04_RS13400	COG2200	EAL domain
FGM04_RS13400	COG2202	Pas domain
FGM04_RS13415	COG2188	Transcriptional regulator
FGM04_RS13420	COG3039	Transposase
FGM04_RS13445	COG1609	Transcriptional regulator
FGM04_RS13475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGM04_RS13490	COG2960	long-chain fatty acid transporting porin activity
FGM04_RS13495	COG5001	Diguanylate cyclase
FGM04_RS13505	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FGM04_RS13520	COG3118	belongs to the thioredoxin family
FGM04_RS13525	COG0513	Belongs to the DEAD box helicase family
FGM04_RS13530	COG0248	Ppx GppA phosphatase
FGM04_RS13540	COG0742	ribosomal rna small subunit methyltransferase
FGM04_RS13555	COG3469	chitinase activity
FGM04_RS13570	COG0084	hydrolase, TatD family'
FGM04_RS13575	COG0805	protein transport
FGM04_RS13580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGM04_RS13585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGM04_RS13590	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FGM04_RS13595	COG3165	ubiquinone biosynthetic process from chorismate
FGM04_RS13600	COG2226	methyltransferase
FGM04_RS13605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGM04_RS13610	COG0402	S-adenosylhomocysteine deaminase activity
FGM04_RS13615	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FGM04_RS13650	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FGM04_RS13655	COG0848	biopolymer transport protein
FGM04_RS13660	COG0811	peptide transport
FGM04_RS13665	COG0811	peptide transport
FGM04_RS13675	COG2771	luxR family
FGM04_RS13680	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGM04_RS13685	COG1349	DNA-binding transcription factor activity
FGM04_RS13690	COG0745	RESPONSE REGULATOR receiver
FGM04_RS13695	COG2205	protein histidine kinase activity
FGM04_RS13710	COG4452	Inner membrane protein CreD
FGM04_RS13715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGM04_RS13720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FGM04_RS13725	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGM04_RS13730	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGM04_RS13735	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGM04_RS13740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGM04_RS13745	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGM04_RS13755	COG0356	it plays a direct role in the translocation of protons across the membrane
FGM04_RS13765	COG1475	DNA binding
FGM04_RS13770	COG1192	Involved in chromosome partitioning
FGM04_RS13775	COG0357	Ribosomal RNA small subunit methyltransferase G
FGM04_RS13780	COG0445	tRNA wobble uridine modification
FGM04_RS13785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FGM04_RS13795	COG4615	Cyclic peptide transporter
FGM04_RS13800	COG1120	ATPase activity
FGM04_RS13805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGM04_RS13815	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FGM04_RS13820	COG0706	membrane insertase activity
FGM04_RS13825	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FGM04_RS13830	COG0594	ribonuclease P activity
FGM04_RS13835	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FGM04_RS13840	COG1126	abc transporter atp-binding protein
FGM04_RS13855	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FGM04_RS13860	COG0592	DNA-directed DNA polymerase activity
FGM04_RS13870	COG0187	DNA topoisomerase II activity
FGM04_RS13880	COG2378	regulation of single-species biofilm formation
FGM04_RS13890	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FGM04_RS13895	COG0071	Belongs to the small heat shock protein (HSP20) family
FGM04_RS13900	COG0071	Belongs to the small heat shock protein (HSP20) family
FGM04_RS13905	COG3977	Valine--pyruvate aminotransferase
FGM04_RS13920	COG2814	Major facilitator Superfamily
FGM04_RS13925	COG0745	RESPONSE REGULATOR receiver
FGM04_RS13930	COG2205	protein histidine kinase activity
FGM04_RS13955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGM04_RS13960	COG4191	Histidine kinase
FGM04_RS13960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_RS13965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGM04_RS13970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_RS13975	COG1309	transcriptional regulator
FGM04_RS14005	COG0561	phosphatase activity
FGM04_RS14010	COG2267	carboxylic ester hydrolase activity
FGM04_RS14020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGM04_RS14025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGM04_RS14030	COG1758	RNA polymerase activity
FGM04_RS14035	COG0194	GDP metabolic process
FGM04_RS14045	COG0859	PFAM glycosyl transferase family 9
FGM04_RS14050	COG3642	lipopolysaccharide core region biosynthetic process
FGM04_RS14090	COG0589	response to stress
FGM04_RS14095	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGM04_RS14100	COG1528	Iron-storage protein
FGM04_RS14105	COG2081	HI0933 family
FGM04_RS14110	COG3275	phosphorelay sensor kinase activity
FGM04_RS14115	COG3279	Response regulator of the LytR AlgR family
FGM04_RS14120	COG2223	nitrite transmembrane transporter activity
FGM04_RS14125	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FGM04_RS14130	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FGM04_RS14145	COG0583	DNA-binding transcription factor activity
FGM04_RS14150	COG4206	TonB-dependent receptor
FGM04_RS14190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FGM04_RS14195	COG2166	iron-sulfur cluster assembly
FGM04_RS14200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGM04_RS14215	COG3245	cytochrome
FGM04_RS14220	COG1063	alcohol dehydrogenase
FGM04_RS14235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGM04_RS14260	COG0110	maltose O-acetyltransferase activity
FGM04_RS14290	COG1280	lysine exporter protein (LysE YggA)
FGM04_RS14330	COG1943	Transposase
FGM04_RS14340	COG0210	DNA helicase
FGM04_RS14355	COG1744	ABC transporter substrate-binding protein PnrA-like
FGM04_RS14360	COG3845	ABC transporter
FGM04_RS14365	COG4603	Belongs to the binding-protein-dependent transport system permease family
FGM04_RS14370	COG1079	Belongs to the binding-protein-dependent transport system permease family
FGM04_RS14375	COG0737	Belongs to the 5'-nucleotidase family
FGM04_RS14385	COG2239	Acts as a magnesium transporter
FGM04_RS14390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGM04_RS14390	COG1648	precorrin-2 dehydrogenase activity
FGM04_RS14395	COG2116	formate transmembrane transporter activity
FGM04_RS14405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGM04_RS14410	COG0842	Transport permease protein
FGM04_RS14415	COG0842	Transport permease protein
FGM04_RS14420	COG1131	(ABC) transporter
FGM04_RS14425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_RS14435	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FGM04_RS14440	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FGM04_RS14450	COG0018	arginyl-trna synthetase
FGM04_RS14460	COG1595	DNA-templated transcription, initiation
FGM04_RS14470	COG1968	undecaprenyl-diphosphatase activity
FGM04_RS14475	COG2017	converts alpha-aldose to the beta-anomer
FGM04_RS14480	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FGM04_RS14485	COG1085	galactose-1-phosphate uridylyltransferase
FGM04_RS14490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGM04_RS14495	COG1609	Transcriptional regulator
FGM04_RS14500	COG3250	beta-galactosidase activity
FGM04_RS14510	COG1129	ABC transporter
FGM04_RS14515	COG4211	Belongs to the binding-protein-dependent transport system permease family
FGM04_RS14525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGM04_RS14540	COG0366	Alpha amylase catalytic
FGM04_RS14555	COG0443	Heat shock 70 kDa protein
FGM04_RS14560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGM04_RS14565	COG3045	CreA protein
FGM04_RS14585	COG0174	glutamine synthetase
FGM04_RS14605	COG3842	ATPase activity
FGM04_RS14610	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGM04_RS14615	COG1177	transmembrane transport
FGM04_RS14620	COG2258	MOSC domain
FGM04_RS14635	COG2050	protein possibly involved in aromatic compounds catabolism
FGM04_RS14640	COG0514	ATP-dependent DNA helicase (RecQ)
FGM04_RS14650	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FGM04_RS14660	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FGM04_RS14665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FGM04_RS14680	COG0254	rRNA binding
FGM04_RS14685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FGM04_RS14695	COG0702	epimerase
FGM04_RS14700	COG0814	amino acid
FGM04_RS14705	COG0281	malic enzyme
FGM04_RS14710	COG1295	ribonuclease BN
FGM04_RS14715	COG1490	D-aminoacyl-tRNA deacylase activity
FGM04_RS14720	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FGM04_RS14725	COG0456	acetyltransferase
FGM04_RS14735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FGM04_RS14740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGM04_RS14750	COG2610	gluconate transmembrane transporter activity
FGM04_RS14755	COG3265	gluconokinase activity
FGM04_RS14760	COG0129	dihydroxy-acid dehydratase activity
FGM04_RS14765	COG0800	Aldolase
FGM04_RS14770	COG1609	Transcriptional regulator
FGM04_RS14780	COG4942	peptidase
FGM04_RS14785	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FGM04_RS14790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGM04_RS14795	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FGM04_RS14800	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FGM04_RS14805	COG0316	Belongs to the HesB IscA family
FGM04_RS14805	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FGM04_RS14810	COG1040	competence protein
FGM04_RS14815	COG0596	Alpha beta hydrolase
FGM04_RS14835	COG2183	response to ionizing radiation
FGM04_RS14840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGM04_RS14860	COG0051	transcription antitermination factor activity, RNA binding
FGM04_RS14865	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FGM04_RS14870	COG0088	Forms part of the polypeptide exit tunnel
FGM04_RS14875	COG0089	rRNA binding
FGM04_RS14880	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGM04_RS14885	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FGM04_RS14890	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FGM04_RS14895	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FGM04_RS14900	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGM04_RS14905	COG0255	Belongs to the universal ribosomal protein uL29 family
FGM04_RS14910	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FGM04_RS14915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FGM04_RS14920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FGM04_RS14925	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGM04_RS14930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGM04_RS14935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FGM04_RS14940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FGM04_RS14945	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FGM04_RS14950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGM04_RS14955	COG1841	ribosomal large subunit assembly
FGM04_RS14960	COG0200	Binds to the 23S rRNA
FGM04_RS14965	COG0201	protein transport
FGM04_RS14970	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGM04_RS14975	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FGM04_RS14980	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FGM04_RS14985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FGM04_RS14990	COG0202	RNA polymerase activity
FGM04_RS14995	COG0203	ribosomal protein L17
FGM04_RS15030	COG4771	TonB-dependent receptor
FGM04_RS15035	COG3706	GGDEF domain
FGM04_RS15065	COG0583	DNA-binding transcription factor activity
FGM04_RS15075	COG1741	Belongs to the pirin family
FGM04_RS15080	COG2259	Doxx family
FGM04_RS15085	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FGM04_RS15090	COG1074	ATP-dependent DNA helicase activity
FGM04_RS15095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGM04_RS15145	COG1175	transmembrane transport
FGM04_RS15155	COG3842	ATPase activity
FGM04_RS15185	COG2873	o-acetylhomoserine
FGM04_RS15195	COG4533	DNA binding
FGM04_RS15215	COG5380	lipid catabolic process
FGM04_RS15220	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FGM04_RS15225	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGM04_RS15250	COG0753	catalase activity
FGM04_RS15255	COG0456	acetyltransferase
FGM04_RS15255	COG0454	-acetyltransferase
FGM04_RS15280	COG2927	DNA polymerase III (CHI subunit)
FGM04_RS15285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FGM04_RS15290	COG0795	lipopolysaccharide-transporting ATPase activity
FGM04_RS15295	COG0795	lipopolysaccharide-transporting ATPase activity
FGM04_RS15310	COG0582	viral genome integration into host DNA
FGM04_RS15405	COG1494	fructose-1,6-bisphosphatase
FGM04_RS15420	COG2959	enzyme of heme biosynthesis
FGM04_RS15430	COG0181	hydroxymethylbilane synthase activity
FGM04_RS15435	COG3072	Adenylate cyclase
FGM04_RS15440	COG0400	carboxylic ester hydrolase activity
FGM04_RS15445	COG1965	Belongs to the frataxin family
FGM04_RS15455	COG0019	diaminopimelate decarboxylase activity
FGM04_RS15460	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FGM04_RS15475	COG1011	Hydrolase
FGM04_RS15495	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FGM04_RS15500	COG3028	Belongs to the UPF0307 family
FGM04_RS15560	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FGM04_RS15590	COG0312	modulator of DNA gyrase
FGM04_RS15600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGM04_RS15605	COG5007	Belongs to the BolA IbaG family
FGM04_RS15615	COG2854	intermembrane phospholipid transfer
FGM04_RS15620	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FGM04_RS15625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FGM04_RS15630	COG1127	ABC transporter
FGM04_RS15635	COG0517	IMP dehydrogenase activity
FGM04_RS15635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FGM04_RS15640	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FGM04_RS15645	COG3117	lipopolysaccharide transmembrane transporter activity
FGM04_RS15650	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FGM04_RS15655	COG1137	ATPase activity
FGM04_RS15670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_RS15675	COG1660	Displays ATPase and GTPase activities
FGM04_RS15680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_RS15685	COG3711	transcriptional antiterminator
FGM04_RS15685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_RS15700	COG3964	amidohydrolase
FGM04_RS15730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGM04_RS15735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGM04_RS15745	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FGM04_RS15750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FGM04_RS15755	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FGM04_RS15760	COG0723	plastoquinol--plastocyanin reductase activity
FGM04_RS15765	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FGM04_RS15770	COG2857	Cytochrome c1
FGM04_RS15775	COG0625	glutathione transferase activity
FGM04_RS15780	COG2969	positive regulation of protein catabolic process
FGM04_RS15785	COG2823	Periplasmic or secreted lipoprotein
FGM04_RS15790	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FGM04_RS15795	COG0792	nuclease activity
FGM04_RS15800	COG3107	peptidoglycan biosynthetic process
FGM04_RS15805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FGM04_RS15815	COG2001	Belongs to the MraZ family
FGM04_RS15820	COG0275	rRNA processing
FGM04_RS15825	COG3116	cell division
FGM04_RS15830	COG0768	penicillin binding
FGM04_RS15840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FGM04_RS15845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGM04_RS15850	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGM04_RS15855	COG0772	Belongs to the SEDS family
FGM04_RS15860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGM04_RS15865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGM04_RS15875	COG0849	cell division
FGM04_RS15880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FGM04_RS15885	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FGM04_RS15895	COG0653	protein targeting
FGM04_RS15905	COG0494	nUDIX hydrolase
FGM04_RS15910	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FGM04_RS15915	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FGM04_RS15930	COG1459	type II secretion system
FGM04_RS15935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGM04_RS15960	COG2186	Transcriptional regulator
FGM04_RS15965	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FGM04_RS15970	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGM04_RS15975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGM04_RS15985	COG0840	transmembrane signaling receptor activity
FGM04_RS15990	COG1752	Esterase of the alpha-beta hydrolase superfamily
FGM04_RS15995	COG1049	propionate catabolic process, 2-methylcitrate cycle
FGM04_RS16000	COG2200	EAL domain
FGM04_RS16010	COG0523	cobalamin synthesis protein
FGM04_RS16030	COG0477	Major facilitator Superfamily
FGM04_RS16045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FGM04_RS16050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FGM04_RS16075	COG3314	Sporulation integral membrane protein YlbJ
FGM04_RS16095	COG0165	Argininosuccinate lyase
FGM04_RS16100	COG0137	argininosuccinate synthase activity
FGM04_RS16110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGM04_RS16115	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FGM04_RS16125	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FGM04_RS16130	COG0110	maltose O-acetyltransferase activity
FGM04_RS16140	COG3706	GGDEF domain
FGM04_RS16145	COG0814	amino acid
FGM04_RS16150	COG3932	Exopolysaccharide synthesis, ExoD
FGM04_RS16165	COG0004	ammonium transporteR
FGM04_RS16170	COG3133	Outer membrane lipoprotein
FGM04_RS16175	COG0456	acetyltransferase
FGM04_RS16195	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FGM04_RS16200	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FGM04_RS16215	COG0671	phosphoesterase, PA-phosphatase related
FGM04_RS16220	COG0628	permease
FGM04_RS16245	COG3284	Transcriptional regulator
FGM04_RS16260	COG1461	Dihydroxyacetone kinase
FGM04_RS16265	COG2376	Dihydroxyacetone kinase
FGM04_RS16270	COG2252	PERMEase
FGM04_RS16275	COG1278	Cold shock
FGM04_RS16285	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FGM04_RS16305	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FGM04_RS16315	COG2194	sulfuric ester hydrolase activity
FGM04_RS16325	COG3039	Transposase
FGM04_RS16355	COG2197	response regulator
FGM04_RS16390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGM04_RS16400	COG3047	cAMP biosynthetic process
FGM04_RS16405	COG0840	transmembrane signaling receptor activity
FGM04_RS16430	COG3135	benzoate transporter
FGM04_RS16435	COG1396	sequence-specific DNA binding
FGM04_RS16475	COG2926	Belongs to the UPF0265 family
FGM04_RS16485	COG0561	phosphatase activity
FGM04_RS16495	COG1058	Belongs to the CinA family
FGM04_RS16495	COG1546	Belongs to the CinA family
FGM04_RS16505	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FGM04_RS16515	COG1522	sequence-specific DNA binding
FGM04_RS16520	COG1368	sulfuric ester hydrolase activity
FGM04_RS16560	COG4221	oxidoreductase activity
FGM04_RS16575	COG1979	alcohol dehydrogenase
FGM04_RS16580	COG1803	Methylglyoxal synthase
FGM04_RS16605	COG1444	tRNA N-acetyltransferase activity
FGM04_RS16610	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_RS16615	COG0835	chemotaxis
FGM04_RS16615	COG0784	Response regulator, receiver
FGM04_RS16625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FGM04_RS16630	COG2949	membrane
FGM04_RS16635	COG3291	Pkd domain containing protein
FGM04_RS16645	COG3039	Transposase
FGM04_RS16650	COG3539	Fimbrial protein
FGM04_RS16660	COG3188	usher protein
FGM04_RS16665	COG3121	Chaperone
FGM04_RS16670	COG3539	Fimbrial protein
FGM04_RS16690	COG1441	menaquinone biosynthetic process
FGM04_RS16695	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FGM04_RS16700	COG0596	Alpha beta hydrolase
FGM04_RS16705	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FGM04_RS16710	COG1169	isochorismate synthase
FGM04_RS16715	COG1575	Belongs to the MenA family. Type 1 subfamily
FGM04_RS16735	COG0513	Belongs to the DEAD box helicase family
FGM04_RS16740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGM04_RS16745	COG1988	membrane-bound metal-dependent
FGM04_RS16750	COG1671	Belongs to the UPF0178 family
FGM04_RS16770	COG0484	heat shock protein binding
FGM04_RS16775	COG3263	regulation of cellular component size
FGM04_RS16780	COG3722	fumarate hydratase activity
FGM04_RS16785	COG0246	Mannitol dehydrogenase
FGM04_RS16790	COG2213	PTS system mannitol-specific
FGM04_RS16790	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_RS16795	COG1560	Kdo2-lipid A biosynthetic process
FGM04_RS16800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FGM04_RS16800	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FGM04_RS16805	COG1538	Outer membrane efflux protein
FGM04_RS16810	COG0494	nUDIX hydrolase
FGM04_RS16815	COG3151	Protein conserved in bacteria
FGM04_RS16825	COG3150	esterase
FGM04_RS16845	COG3104	oligopeptide transport
FGM04_RS16880	COG0583	DNA-binding transcription factor activity
FGM04_RS16885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGM04_RS16905	COG0204	Acyl-transferase
FGM04_RS16910	COG1842	Phage shock protein A
FGM04_RS16925	COG2827	Endonuclease containing a URI domain
FGM04_RS16940	COG1573	uracil-dna glycosylase
FGM04_RS16945	COG0697	spore germination
FGM04_RS16950	COG0583	DNA-binding transcription factor activity
FGM04_RS16955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGM04_RS16960	COG1121	(ABC) transporter
FGM04_RS16965	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FGM04_RS16995	COG0739	heme binding
FGM04_RS17005	COG3068	Protein conserved in bacteria
FGM04_RS17015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FGM04_RS17015	COG3008	intermembrane lipid transfer
FGM04_RS17020	COG2995	paraquat-inducible protein a
FGM04_RS17030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGM04_RS17040	COG4251	negative regulation of phosphorylation
FGM04_RS17040	COG3706	GGDEF domain
FGM04_RS17040	COG2203	Gaf domain
FGM04_RS17040	COG5001	Diguanylate cyclase
FGM04_RS17045	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FGM04_RS17060	COG2771	luxR family
FGM04_RS17070	COG0840	transmembrane signaling receptor activity
FGM04_RS17075	COG0632	four-way junction helicase activity
FGM04_RS17080	COG2255	four-way junction helicase activity
FGM04_RS17090	COG1294	oxidase, subunit
FGM04_RS17095	COG4890	Cyd operon protein YbgT
FGM04_RS17100	COG3790	cyd operon protein YbgE
FGM04_RS17105	COG0824	Thioesterase
FGM04_RS17110	COG0811	peptide transport
FGM04_RS17125	COG0823	Involved in the tonB-independent uptake of proteins
FGM04_RS17130	COG2885	chlorophyll binding
FGM04_RS17135	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FGM04_RS17200	COG0733	neurotransmitter:sodium symporter activity
FGM04_RS17210	COG0733	neurotransmitter:sodium symporter activity
FGM04_RS17225	COG0561	phosphatase activity
FGM04_RS17275	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FGM04_RS17280	COG1640	4-alpha-glucanotransferase
FGM04_RS17285	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FGM04_RS17295	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FGM04_RS17300	COG0840	transmembrane signaling receptor activity
FGM04_RS17305	COG1585	Membrane protein implicated in regulation of membrane protease activity
FGM04_RS17310	COG0330	HflC and HflK could
FGM04_RS17315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGM04_RS17315	COG1648	precorrin-2 dehydrogenase activity
FGM04_RS17320	COG0175	sulfate reduction
FGM04_RS17325	COG2895	sulfate adenylyltransferase (ATP) activity
FGM04_RS17330	COG3273	potassium ion transport
FGM04_RS17330	COG0471	metal ion transport
FGM04_RS17335	COG0529	Catalyzes the synthesis of activated sulfate
FGM04_RS17370	COG0840	transmembrane signaling receptor activity
FGM04_RS17390	COG1136	(ABC) transporter
FGM04_RS17405	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FGM04_RS17420	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FGM04_RS17425	COG0784	Response regulator, receiver
FGM04_RS17425	COG3437	response regulator, receiver
FGM04_RS17435	COG2076	Multidrug Resistance protein
FGM04_RS17440	COG2076	Multidrug Resistance protein
FGM04_RS17445	COG3039	Transposase
FGM04_RS17455	COG0346	lactoylglutathione lyase activity
FGM04_RS17460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGM04_RS17465	COG1643	Atp-dependent helicase
FGM04_RS17475	COG1489	DNA binding
FGM04_RS17480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FGM04_RS17485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGM04_RS17495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FGM04_RS17500	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FGM04_RS17505	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FGM04_RS17515	COG1823	symporter activity
FGM04_RS17535	COG1924	4 iron, 4 sulfur cluster binding
FGM04_RS17540	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FGM04_RS17545	COG0842	Transport permease protein
FGM04_RS17550	COG1131	(ABC) transporter
FGM04_RS17565	COG0163	prenyltransferase activity
FGM04_RS17570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGM04_RS17575	COG0671	phosphoesterase, PA-phosphatase related
FGM04_RS17580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGM04_RS17585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGM04_RS17585	COG1017	nitric oxide dioxygenase activity
FGM04_RS17590	COG1151	hydroxylamine reductase activity
FGM04_RS17595	COG0783	Belongs to the Dps family
FGM04_RS17600	COG3023	N-Acetylmuramoyl-L-alanine amidase
FGM04_RS17605	COG4807	Protein conserved in bacteria
FGM04_RS17615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGM04_RS17620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGM04_RS17625	COG3956	TIGRFAM MazG family protein
FGM04_RS17630	COG0504	CTP synthase activity
FGM04_RS17635	COG0148	phosphopyruvate hydratase activity
FGM04_RS17650	COG2801	Transposase and inactivated derivatives
FGM04_RS17685	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FGM04_RS17695	COG0488	(ABC) transporter
FGM04_RS17700	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FGM04_RS17700	COG0517	IMP dehydrogenase activity
FGM04_RS17715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGM04_RS17730	COG1794	racemase activity, acting on amino acids and derivatives
FGM04_RS17740	COG2731	YhcH YjgK YiaL family protein
FGM04_RS17750	COG0668	transmembrane transport
FGM04_RS17755	COG1376	ErfK ybiS ycfS ynhG family protein
FGM04_RS17765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGM04_RS17770	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FGM04_RS17775	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FGM04_RS17785	COG0585	pseudouridine synthase activity
FGM04_RS17790	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FGM04_RS17795	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FGM04_RS17800	COG1238	metal cluster binding
FGM04_RS17815	COG1902	pentaerythritol trinitrate reductase activity
FGM04_RS17825	COG2852	Protein conserved in bacteria
FGM04_RS17840	COG2957	Belongs to the agmatine deiminase family
FGM04_RS17845	COG0154	amidase activity
FGM04_RS17870	COG0513	Belongs to the DEAD box helicase family
FGM04_RS17875	COG2199	diguanylate cyclase activity
FGM04_RS17875	COG2203	Gaf domain
FGM04_RS17885	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
FGM04_RS17890	COG1858	cytochrome C peroxidase
FGM04_RS17935	COG2816	NAD+ diphosphatase activity
FGM04_RS17970	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FGM04_RS17975	COG2252	PERMEase
FGM04_RS17985	COG0488	(ABC) transporter
FGM04_RS18000	COG0741	lytic transglycosylase activity
FGM04_RS18020	COG3416	Protein conserved in bacteria
FGM04_RS18035	COG4608	Belongs to the ABC transporter superfamily
FGM04_RS18040	COG0444	Belongs to the ABC transporter superfamily
FGM04_RS18050	COG4239	(ABC) transporter, permease
FGM04_RS18055	COG4174	ABC transporter (Permease)
FGM04_RS18060	COG4206	TonB-dependent receptor
FGM04_RS18070	COG0811	peptide transport
FGM04_RS18075	COG0811	peptide transport
FGM04_RS18080	COG0848	biopolymer transport protein
FGM04_RS18100	COG3385	transposase activity
FGM04_RS18110	COG0439	Biotin carboxylase
FGM04_RS18115	COG0511	ligase activity, forming carbon-carbon bonds
FGM04_RS18120	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FGM04_RS18125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGM04_RS18145	COG3381	protein complex oligomerization
FGM04_RS18155	COG3005	denitrification pathway
FGM04_RS18160	COG0745	RESPONSE REGULATOR receiver
FGM04_RS18170	COG1879	ABC-type sugar transport system periplasmic component
FGM04_RS18175	COG2198	Histidine kinase
FGM04_RS18175	COG2205	protein histidine kinase activity
FGM04_RS18175	COG0784	Response regulator, receiver
FGM04_RS18185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGM04_RS18190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FGM04_RS18195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGM04_RS18195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGM04_RS18210	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FGM04_RS18215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGM04_RS18220	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FGM04_RS18225	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FGM04_RS18240	COG0601	transmembrane transport
FGM04_RS18250	COG1047	Peptidyl-prolyl cis-trans
FGM04_RS18255	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FGM04_RS18265	COG0784	Response regulator, receiver
FGM04_RS18265	COG0835	chemotaxis
FGM04_RS18270	COG0429	hydrolase of the alpha beta-hydrolase fold
FGM04_RS18275	COG4251	negative regulation of phosphorylation
FGM04_RS18275	COG2203	Gaf domain
FGM04_RS18275	COG5001	Diguanylate cyclase
FGM04_RS18275	COG3706	GGDEF domain
FGM04_RS18280	COG3089	Belongs to the UPF0270 family
FGM04_RS18285	COG3954	Phosphoribulokinase
FGM04_RS18300	COG1765	OsmC-like protein
FGM04_RS18330	COG2814	Major facilitator Superfamily
FGM04_RS18340	COG3655	Transcriptional regulator
FGM04_RS18350	COG2205	protein histidine kinase activity
FGM04_RS18350	COG5002	protein histidine kinase activity
FGM04_RS18350	COG0784	Response regulator, receiver
FGM04_RS18360	COG3706	GGDEF domain
FGM04_RS18375	COG3397	chitin binding
FGM04_RS18420	COG0784	Response regulator, receiver
FGM04_RS18420	COG0835	chemotaxis
FGM04_RS18425	COG2755	lipolytic protein G-D-S-L family
FGM04_RS18430	COG4181	ATPase activity
FGM04_RS18435	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FGM04_RS18440	COG1090	epimerase
FGM04_RS18445	COG2200	EAL domain
FGM04_RS18450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGM04_RS18455	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FGM04_RS18460	COG3171	Protein conserved in bacteria
FGM04_RS18465	COG2066	Belongs to the glutaminase family
FGM04_RS18470	COG2897	thiosulfate sulfurtransferase activity
FGM04_RS18485	COG0521	Mo-molybdopterin cofactor biosynthetic process
FGM04_RS18495	COG2966	Psort location CytoplasmicMembrane, score
FGM04_RS18500	COG3610	response to peptide
FGM04_RS18515	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGM04_RS18520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FGM04_RS18530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGM04_RS18545	COG0786	glutamate:sodium symporter activity
FGM04_RS18550	COG0252	asparaginase activity
FGM04_RS18555	COG3139	Protein of unknown function (DUF1315)
FGM04_RS18575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FGM04_RS18580	COG0321	lipoyl(octanoyl) transferase activity
FGM04_RS18585	COG2921	Belongs to the UPF0250 family
FGM04_RS18590	COG1686	Belongs to the peptidase S11 family
FGM04_RS18595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FGM04_RS18600	COG2951	lytic endotransglycosylase activity
FGM04_RS18605	COG0772	Belongs to the SEDS family
FGM04_RS18610	COG0768	penicillin binding
FGM04_RS18615	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FGM04_RS18620	COG0799	negative regulation of ribosome biogenesis
FGM04_RS18625	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FGM04_RS18640	COG0495	leucyl-tRNA aminoacylation
FGM04_RS18645	COG2888	peptidyl-tyrosine sulfation
FGM04_RS18650	COG0312	modulator of DNA gyrase
FGM04_RS18660	COG0716	FMN binding
FGM04_RS18665	COG4974	Belongs to the 'phage' integrase family
FGM04_RS18675	COG1970	mechanosensitive ion channel activity
FGM04_RS18685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FGM04_RS18690	COG0789	Transcriptional regulator
FGM04_RS18695	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FGM04_RS18700	COG4535	Mg2 and Co2 transporter CorC
FGM04_RS18705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGM04_RS18710	COG1702	phosphate starvation-inducible protein PhoH
FGM04_RS18715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGM04_RS18720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGM04_RS18725	COG1335	isochorismatase
FGM04_RS18735	COG3706	GGDEF domain
FGM04_RS18740	COG0583	DNA-binding transcription factor activity
FGM04_RS18765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGM04_RS18775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FGM04_RS18785	COG0516	GMP reductase activity
FGM04_RS18795	COG0642	Histidine kinase
FGM04_RS18810	COG4221	oxidoreductase activity
FGM04_RS18820	COG1022	Amp-dependent synthetase and ligase
FGM04_RS18835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_RS18850	COG3214	Protein conserved in bacteria
FGM04_RS18860	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGM04_RS18865	COG0700	Nucleoside recognition
FGM04_RS18870	COG3366	ferrous iron transmembrane transporter activity
FGM04_RS18875	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FGM04_RS18880	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FGM04_RS18885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FGM04_RS18890	COG1053	succinate dehydrogenase
FGM04_RS18900	COG0584	glycerophosphoryl diester phosphodiesterase
FGM04_RS18905	COG1511	domain protein
FGM04_RS18905	COG3264	Mechanosensitive ion channel
FGM04_RS18915	COG0739	heme binding
FGM04_RS18925	COG0583	DNA-binding transcription factor activity
FGM04_RS18945	COG0583	DNA-binding transcription factor activity
FGM04_RS18950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FGM04_RS18980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGM04_RS18985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FGM04_RS18995	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FGM04_RS19000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FGM04_RS19010	COG0180	Tryptophanyl-tRNA synthetase
FGM04_RS19025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGM04_RS19035	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_RS19050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGM04_RS19060	COG0674	pyruvate-flavodoxin oxidoreductase activity
FGM04_RS19060	COG1013	pyruvate-flavodoxin oxidoreductase activity
FGM04_RS19060	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FGM04_RS19060	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_RS19065	COG0366	Alpha amylase catalytic
FGM04_RS19080	COG3097	Belongs to the UPF0267 family
FGM04_RS19090	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FGM04_RS19100	COG0471	metal ion transport
FGM04_RS19100	COG0490	domain, Protein
FGM04_RS19145	COG0012	GTP binding
FGM04_RS19150	COG0193	aminoacyl-tRNA hydrolase activity
FGM04_RS19155	COG0737	Belongs to the 5'-nucleotidase family
FGM04_RS19160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGM04_RS19170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FGM04_RS19175	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FGM04_RS19180	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FGM04_RS19185	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FGM04_RS19190	COG2890	protein-(glutamine-N5) methyltransferase activity
FGM04_RS19200	COG2912	Transglutaminase-like superfamily
FGM04_RS19205	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FGM04_RS19210	COG1301	dicarboxylic acid transport
FGM04_RS19225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FGM04_RS19235	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FGM04_RS19235	COG3408	Glycogen debranching enzyme
FGM04_RS19245	COG1881	PFAM PEBP family protein
FGM04_RS19250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FGM04_RS19265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FGM04_RS19275	COG0583	DNA-binding transcription factor activity
FGM04_RS19280	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_RS19285	COG0616	signal peptide processing
FGM04_RS19290	COG2211	Major facilitator Superfamily
FGM04_RS19295	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FGM04_RS19305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGM04_RS19310	COG0826	peptidase U32
FGM04_RS19315	COG2199	diguanylate cyclase activity
FGM04_RS19315	COG2200	EAL domain
FGM04_RS19315	COG2203	Gaf domain
FGM04_RS19325	COG3039	Transposase
FGM04_RS19355	COG3724	N-succinylarginine dihydrolase activity
FGM04_RS19370	COG0840	transmembrane signaling receptor activity
FGM04_RS19390	COG4608	Belongs to the ABC transporter superfamily
FGM04_RS19395	COG0444	Belongs to the ABC transporter superfamily
FGM04_RS19400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGM04_RS19415	COG0784	Response regulator, receiver
FGM04_RS19415	COG2205	protein histidine kinase activity
FGM04_RS19445	COG3220	belongs to the UPF0276 family
FGM04_RS19475	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGM04_RS19480	COG1289	transmembrane transporter activity
FGM04_RS19485	COG0303	'Molybdopterin
FGM04_RS19490	COG0746	molybdenum cofactor guanylyltransferase activity
FGM04_RS19500	COG4662	Binding-protein-dependent transport system inner membrane component
FGM04_RS19510	COG2204	response regulator
FGM04_RS19515	COG3852	Histidine kinase
FGM04_RS19525	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FGM04_RS19565	COG3383	formate dehydrogenase (NAD+) activity
FGM04_RS19565	COG3383	formate dehydrogenase (NAD+) activity
FGM04_RS19570	COG0437	4 iron, 4 sulfur cluster binding
FGM04_RS19590	COG0281	malic enzyme
FGM04_RS19620	COG0531	amino acid
FGM04_RS19625	COG1752	Esterase of the alpha-beta hydrolase superfamily
FGM04_RS19630	COG3706	GGDEF domain
FGM04_RS19635	COG1566	PFAM secretion protein HlyD family protein
FGM04_RS19645	COG1032	radical SAM domain protein
FGM04_RS19670	COG0583	DNA-binding transcription factor activity
FGM04_RS19675	COG0673	inositol 2-dehydrogenase activity
FGM04_RS19680	COG2920	part of a sulfur-relay system
FGM04_RS19685	COG1289	transmembrane transporter activity
FGM04_RS19690	COG0670	Belongs to the BI1 family
FGM04_RS19705	COG1486	melibiose metabolic process
FGM04_RS19710	COG1917	Cupin 2, conserved barrel domain protein
FGM04_RS19710	COG2169	Transcriptional regulator
FGM04_RS19715	COG1447	Phosphotransferase system cellobiose-specific component IIA
FGM04_RS19720	COG2723	6-phospho-beta-galactosidase activity
FGM04_RS19725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGM04_RS19730	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGM04_RS19740	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FGM04_RS19750	COG3156	type II secretion system protein K
FGM04_RS19755	COG4795	General secretion pathway protein
FGM04_RS19760	COG2165	general secretion pathway protein
FGM04_RS19770	COG2165	general secretion pathway protein
FGM04_RS19775	COG1459	type II secretion system
FGM04_RS19780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGM04_RS19790	COG3031	protein transport across the cell outer membrane
FGM04_RS19800	COG3409	Peptidoglycan-binding domain 1 protein
FGM04_RS19800	COG3267	Type II secretory pathway component ExeA
FGM04_RS19805	COG3437	response regulator, receiver
FGM04_RS19805	COG2770	Histidine kinase
FGM04_RS19820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGM04_RS19825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGM04_RS19830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_RS19840	COG2190	(PTS) system
FGM04_RS19850	COG3590	peptidase
FGM04_RS19860	COG1196	nuclear chromosome segregation
FGM04_RS19860	COG3264	Mechanosensitive ion channel
FGM04_RS19865	COG0469	pyruvate kinase activity
FGM04_RS19875	COG3384	dioxygenase
FGM04_RS19880	COG0419	ATPase involved in DNA repair
FGM04_RS19885	COG0420	3'-5' exonuclease activity
FGM04_RS19895	COG2974	May be involved in recombination
FGM04_RS19900	COG0405	Gamma-glutamyltransferase
FGM04_RS19905	COG0545	Peptidyl-prolyl cis-trans isomerase
FGM04_RS19910	COG1283	sodium-dependent phosphate transmembrane transporter activity
FGM04_RS19920	COG0531	amino acid
FGM04_RS19930	COG0531	amino acid
FGM04_RS19945	COG1917	Cupin 2, conserved barrel domain protein
FGM04_RS19945	COG1396	sequence-specific DNA binding
FGM04_RS19950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_RS19980	COG0259	pyridoxamine-phosphate oxidase activity
FGM04_RS19985	COG0625	glutathione transferase activity
FGM04_RS20005	COG2850	peptidyl-arginine hydroxylation
FGM04_RS20010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGM04_RS20015	COG2915	High frequency lysogenization protein hflD homolog
FGM04_RS20020	COG0482	sulfurtransferase activity
FGM04_RS20030	COG1187	pseudouridine synthase activity
FGM04_RS20040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_RS20045	COG2271	Major facilitator Superfamily
FGM04_RS20050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_RS20050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_RS20050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_RS20065	COG3039	Transposase
FGM04_RS20075	COG3039	Transposase
FGM04_RS20100	COG1609	Transcriptional regulator
FGM04_RS20105	COG1263	PTS System
FGM04_RS20105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_RS20110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FGM04_RS20115	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FGM04_RS20125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGM04_RS20130	COG1960	acyl-CoA dehydrogenase activity
FGM04_RS20140	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FGM04_RS20155	COG4983	Phage plasmid primase, P4 family domain protein
FGM04_RS20175	COG5377	YqaJ viral recombinase family
FGM04_RS20220	COG2003	Belongs to the UPF0758 family
FGM04_RS20295	COG3039	Transposase
FGM04_RS20305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGM04_RS20330	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FGM04_RS20370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGM04_RS20385	COG1940	carbohydrate kinase activity
FGM04_RS20390	COG0457	Tetratricopeptide repeat
FGM04_RS20395	COG2814	Major facilitator Superfamily
FGM04_RS20395	COG0477	Major facilitator Superfamily
FGM04_RS20405	COG3383	formate dehydrogenase (NAD+) activity
FGM04_RS20425	COG3039	Transposase
FGM04_RS20490	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FGM04_RS20495	COG2867	negative regulation of translational initiation
FGM04_RS20500	COG2914	Belongs to the UPF0125 (RnfH) family
FGM04_RS20505	COG1473	amidohydrolase
FGM04_RS20510	COG1960	acyl-CoA dehydrogenase activity
FGM04_RS20515	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FGM04_RS20520	COG0121	glutamine amidotransferase
FGM04_RS20550	COG2197	response regulator
FGM04_RS20555	COG3850	Histidine kinase
FGM04_RS20560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FGM04_RS20565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGM04_RS20575	COG0243	molybdopterin cofactor binding
FGM04_RS20580	COG0437	4 iron, 4 sulfur cluster binding
FGM04_RS20585	COG0348	domain, Protein
FGM04_RS20595	COG3005	denitrification pathway
FGM04_RS20600	COG0521	Mo-molybdopterin cofactor biosynthetic process
FGM04_RS20605	COG0315	cyclic pyranopterin monophosphate synthase activity
FGM04_RS20610	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FGM04_RS20615	COG0314	molybdopterin synthase activity
FGM04_RS20630	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FGM04_RS20635	COG2267	carboxylic ester hydrolase activity
FGM04_RS20640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FGM04_RS20645	COG0303	'Molybdopterin
FGM04_RS20650	COG0302	gtp cyclohydrolase
FGM04_RS20655	COG0840	transmembrane signaling receptor activity
FGM04_RS20660	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FGM04_RS20675	COG2353	YceI-like domain
FGM04_RS20685	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FGM04_RS20720	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGM04_RS20725	COG1166	arginine decarboxylase activity
FGM04_RS20745	COG0814	amino acid
FGM04_RS20755	COG3681	Belongs to the UPF0597 family
FGM04_RS20760	COG2964	Protein conserved in bacteria
FGM04_RS20770	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGM04_RS20775	COG1288	antiporter activity
FGM04_RS20790	COG1280	lysine exporter protein (LysE YggA)
FGM04_RS20805	COG3263	regulation of cellular component size
FGM04_RS20815	COG1876	peptidase activity
FGM04_RS20820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGM04_RS20825	COG1393	Belongs to the ArsC family
FGM04_RS20835	COG3069	C4-dicarboxylate transmembrane transporter activity
FGM04_RS20840	COG1473	amidohydrolase
FGM04_RS20850	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FGM04_RS20860	COG0017	Asparaginyl-tRNA synthetase
FGM04_RS20875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FGM04_RS20880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FGM04_RS20885	COG0156	8-amino-7-oxononanoate synthase activity
FGM04_RS20890	COG2226	methyltransferase
FGM04_RS20890	COG1073	alpha beta
FGM04_RS20895	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FGM04_RS20900	COG0501	Belongs to the peptidase M48B family
FGM04_RS20915	COG1376	ErfK ybiS ycfS ynhG family protein
FGM04_RS20915	COG1388	LysM domain
FGM04_RS20925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGM04_RS20930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_RS20935	COG0745	RESPONSE REGULATOR receiver
FGM04_RS20940	COG5002	protein histidine kinase activity
FGM04_RS20940	COG5000	phosphorelay sensor kinase activity
FGM04_RS20965	COG1388	LysM domain
FGM04_RS20965	COG0741	lytic transglycosylase activity
FGM04_RS20970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGM04_RS20975	COG2226	methyltransferase
FGM04_RS20980	COG0328	RNA-DNA hybrid ribonuclease activity
FGM04_RS20985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FGM04_RS20995	COG0784	Response regulator, receiver
FGM04_RS20995	COG3437	response regulator, receiver
FGM04_RS21000	COG2375	cellular response to nickel ion
FGM04_RS21005	COG4771	TonB-dependent receptor
FGM04_RS21010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGM04_RS21015	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGM04_RS21020	COG1120	ATPase activity
FGM04_RS21025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGM04_RS21035	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGM04_RS21040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_RS21065	COG0708	Exodeoxyribonuclease III
FGM04_RS21095	COG3132	Protein of unknown function, DUF480
FGM04_RS21100	COG3300	MHYT domain
FGM04_RS21100	COG5001	Diguanylate cyclase
FGM04_RS21110	COG2801	Transposase and inactivated derivatives
FGM04_RS21120	COG2841	Protein conserved in bacteria
FGM04_RS21130	COG0534	Mate efflux family protein
FGM04_RS21165	COG1309	transcriptional regulator
FGM04_RS21200	COG3152	Membrane
FGM04_RS21215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_RS21220	COG0840	transmembrane signaling receptor activity
FGM04_RS21225	COG1482	cell wall glycoprotein biosynthetic process
FGM04_RS21230	COG2207	Transcriptional regulator
FGM04_RS21235	COG0538	isocitrate dehydrogenase activity
FGM04_RS21245	COG3048	D-serine ammonia-lyase activity
FGM04_RS21250	COG2610	gluconate transmembrane transporter activity
FGM04_RS21255	COG0583	DNA-binding transcription factor activity
FGM04_RS21265	COG0791	NLP P60 protein
FGM04_RS21270	COG0583	DNA-binding transcription factor activity
FGM04_RS21275	COG0450	alkyl hydroperoxide reductase
FGM04_RS21295	COG0500	methyltransferase
FGM04_RS21300	COG4106	trans-aconitate 2-methyltransferase activity
FGM04_RS21305	COG1801	Protein of unknown function DUF72
FGM04_RS21315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FGM04_RS21320	COG0217	transcriptional regulatory protein
FGM04_RS21430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGM04_RS21480	COG1192	Involved in chromosome partitioning
FGM04_RS21530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGM04_RS21600	COG2336	PFAM SpoVT AbrB
FGM04_RS21810	COG1121	(ABC) transporter
FGM04_RS21830	COG3550	peptidyl-serine autophosphorylation
FGM04_RS21835	COG1396	sequence-specific DNA binding
FGM04_RS21965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGM04_RS22030	COG0714	Associated with various cellular activities
FGM04_RS22120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process