locus-tag	class	description
AMS64_RS00020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMS64_RS00025	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AMS64_RS00030	COG1561	YicC-like family, N-terminal region
AMS64_RS00035	COG0583	DNA-binding transcription factor activity
AMS64_RS00055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMS64_RS00060	COG0385	Bile acid
AMS64_RS00065	COG0531	amino acid
AMS64_RS00070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMS64_RS00075	COG0531	amino acid
AMS64_RS00080	COG2731	YhcH YjgK YiaL family protein
AMS64_RS00085	COG3250	beta-galactosidase activity
AMS64_RS00090	COG1609	Transcriptional regulator
AMS64_RS00150	COG0583	DNA-binding transcription factor activity
AMS64_RS00165	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AMS64_RS00170	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AMS64_RS00175	COG2223	nitrite transmembrane transporter activity
AMS64_RS00180	COG3279	Response regulator of the LytR AlgR family
AMS64_RS00185	COG3275	phosphorelay sensor kinase activity
AMS64_RS00190	COG2081	HI0933 family
AMS64_RS00195	COG1528	Iron-storage protein
AMS64_RS00200	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMS64_RS00205	COG0589	response to stress
AMS64_RS00240	COG3642	lipopolysaccharide core region biosynthetic process
AMS64_RS00245	COG0859	PFAM glycosyl transferase family 9
AMS64_RS00255	COG0194	GDP metabolic process
AMS64_RS00260	COG1758	RNA polymerase activity
AMS64_RS00265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMS64_RS00270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMS64_RS00280	COG2267	carboxylic ester hydrolase activity
AMS64_RS00285	COG0561	phosphatase activity
AMS64_RS00315	COG1309	transcriptional regulator
AMS64_RS00320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_RS00325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_RS00330	COG4191	Histidine kinase
AMS64_RS00330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_RS00335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMS64_RS00355	COG2205	protein histidine kinase activity
AMS64_RS00360	COG0745	RESPONSE REGULATOR receiver
AMS64_RS00365	COG2814	Major facilitator Superfamily
AMS64_RS00375	COG3977	Valine--pyruvate aminotransferase
AMS64_RS00380	COG0071	Belongs to the small heat shock protein (HSP20) family
AMS64_RS00385	COG0071	Belongs to the small heat shock protein (HSP20) family
AMS64_RS00390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMS64_RS00400	COG2378	regulation of single-species biofilm formation
AMS64_RS00415	COG0187	DNA topoisomerase II activity
AMS64_RS00425	COG0592	DNA-directed DNA polymerase activity
AMS64_RS00430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMS64_RS00445	COG1126	abc transporter atp-binding protein
AMS64_RS00450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AMS64_RS00455	COG0594	ribonuclease P activity
AMS64_RS00460	COG0706	membrane insertase activity
AMS64_RS00465	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AMS64_RS00475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMS64_RS00480	COG1120	ATPase activity
AMS64_RS00485	COG4615	Cyclic peptide transporter
AMS64_RS00490	COG4774	siderophore transport
AMS64_RS00495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMS64_RS00500	COG0445	tRNA wobble uridine modification
AMS64_RS00505	COG0357	Ribosomal RNA small subunit methyltransferase G
AMS64_RS00510	COG1192	Involved in chromosome partitioning
AMS64_RS00515	COG1475	DNA binding
AMS64_RS00525	COG0356	it plays a direct role in the translocation of protons across the membrane
AMS64_RS00535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMS64_RS00540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMS64_RS00545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMS64_RS00550	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMS64_RS00555	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMS64_RS00560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMS64_RS00565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AMS64_RS00570	COG4452	Inner membrane protein CreD
AMS64_RS00585	COG2205	protein histidine kinase activity
AMS64_RS00590	COG0745	RESPONSE REGULATOR receiver
AMS64_RS00595	COG1349	DNA-binding transcription factor activity
AMS64_RS00600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMS64_RS00605	COG2771	luxR family
AMS64_RS00615	COG0811	peptide transport
AMS64_RS00620	COG0811	peptide transport
AMS64_RS00625	COG0848	biopolymer transport protein
AMS64_RS00630	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AMS64_RS00665	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AMS64_RS00670	COG0402	S-adenosylhomocysteine deaminase activity
AMS64_RS00675	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMS64_RS00680	COG2226	methyltransferase
AMS64_RS00685	COG3165	ubiquinone biosynthetic process from chorismate
AMS64_RS00690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMS64_RS00695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMS64_RS00700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMS64_RS00705	COG0805	protein transport
AMS64_RS00710	COG0084	hydrolase, TatD family'
AMS64_RS00720	COG3397	chitin binding
AMS64_RS00725	COG3469	chitinase activity
AMS64_RS00750	COG0742	ribosomal rna small subunit methyltransferase
AMS64_RS00760	COG0248	Ppx GppA phosphatase
AMS64_RS00765	COG0513	Belongs to the DEAD box helicase family
AMS64_RS00770	COG3118	belongs to the thioredoxin family
AMS64_RS00785	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AMS64_RS00795	COG5001	Diguanylate cyclase
AMS64_RS00800	COG2960	long-chain fatty acid transporting porin activity
AMS64_RS00815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMS64_RS00845	COG1609	Transcriptional regulator
AMS64_RS00880	COG0751	glycine-tRNA ligase activity
AMS64_RS00885	COG0752	glycyl-tRNA synthetase alpha subunit
AMS64_RS00890	COG2818	Glycosylase
AMS64_RS00895	COG2885	chlorophyll binding
AMS64_RS00900	COG0251	oxidation-reduction process
AMS64_RS00905	COG0425	Belongs to the sulfur carrier protein TusA family
AMS64_RS00930	COG0183	Belongs to the thiolase family
AMS64_RS00935	COG1024	Enoyl-CoA hydratase
AMS64_RS00935	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMS64_RS00940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMS64_RS00945	COG0006	proline dipeptidase activity
AMS64_RS00950	COG1739	Uncharacterized protein family UPF0029
AMS64_RS00955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMS64_RS00960	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AMS64_RS00990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMS64_RS00990	COG0045	succinate-CoA ligase (ADP-forming) activity
AMS64_RS00990	COG1042	CoA-binding domain protein
AMS64_RS01010	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AMS64_RS01015	COG0166	Belongs to the GPI family
AMS64_RS01020	COG0668	transmembrane transport
AMS64_RS01025	COG1309	transcriptional regulator
AMS64_RS01030	COG0756	dUTP diphosphatase activity
AMS64_RS01035	COG0756	dUTP diphosphatase activity
AMS64_RS01085	COG2916	Histone family protein nucleoid-structuring protein H-NS
AMS64_RS01100	COG5642	Protein of unknown function (DUF2384)
AMS64_RS01120	COG0210	DNA helicase
AMS64_RS01145	COG4974	Belongs to the 'phage' integrase family
AMS64_RS01150	COG0756	dUTP diphosphatase activity
AMS64_RS01155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMS64_RS01160	COG2003	Belongs to the UPF0758 family
AMS64_RS01165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMS64_RS01170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMS64_RS01180	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMS64_RS01185	COG2990	Protein conserved in bacteria
AMS64_RS01190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMS64_RS01195	COG0859	PFAM glycosyl transferase family 9
AMS64_RS01200	COG0463	Glycosyl transferase, family 2
AMS64_RS01205	COG0859	PFAM glycosyl transferase family 9
AMS64_RS01210	COG1519	Transferase
AMS64_RS01215	COG0604	alcohol dehydrogenase
AMS64_RS01230	COG3161	chorismate lyase activity
AMS64_RS01235	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AMS64_RS01240	COG2937	Belongs to the GPAT DAPAT family
AMS64_RS01245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMS64_RS01260	COG0534	Mate efflux family protein
AMS64_RS01265	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AMS64_RS01270	COG2205	protein histidine kinase activity
AMS64_RS01275	COG0745	RESPONSE REGULATOR receiver
AMS64_RS01285	COG1045	serine acetyltransferase
AMS64_RS01295	COG3074	FtsZ-dependent cytokinesis
AMS64_RS01300	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AMS64_RS01310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AMS64_RS01335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AMS64_RS01340	COG2166	iron-sulfur cluster assembly
AMS64_RS01345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMS64_RS01360	COG3245	cytochrome
AMS64_RS01365	COG1063	alcohol dehydrogenase
AMS64_RS01380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMS64_RS01395	COG3307	-O-antigen
AMS64_RS01400	COG3306	glycosyltransferase involved in LPS biosynthesis
AMS64_RS01435	COG1280	lysine exporter protein (LysE YggA)
AMS64_RS01480	COG0210	DNA helicase
AMS64_RS01485	COG1744	ABC transporter substrate-binding protein PnrA-like
AMS64_RS01490	COG3845	ABC transporter
AMS64_RS01495	COG4603	Belongs to the binding-protein-dependent transport system permease family
AMS64_RS01500	COG1079	Belongs to the binding-protein-dependent transport system permease family
AMS64_RS01505	COG0737	Belongs to the 5'-nucleotidase family
AMS64_RS01515	COG2239	Acts as a magnesium transporter
AMS64_RS01520	COG1648	precorrin-2 dehydrogenase activity
AMS64_RS01520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMS64_RS01525	COG2116	formate transmembrane transporter activity
AMS64_RS01535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMS64_RS01540	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AMS64_RS01545	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AMS64_RS01555	COG0018	arginyl-trna synthetase
AMS64_RS01565	COG1595	DNA-templated transcription, initiation
AMS64_RS01575	COG1968	undecaprenyl-diphosphatase activity
AMS64_RS01580	COG2017	converts alpha-aldose to the beta-anomer
AMS64_RS01585	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AMS64_RS01590	COG1085	galactose-1-phosphate uridylyltransferase
AMS64_RS01595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMS64_RS01600	COG1609	Transcriptional regulator
AMS64_RS01605	COG3250	beta-galactosidase activity
AMS64_RS01615	COG1129	ABC transporter
AMS64_RS01620	COG4211	Belongs to the binding-protein-dependent transport system permease family
AMS64_RS01630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMS64_RS01645	COG0366	Alpha amylase catalytic
AMS64_RS01660	COG0443	Heat shock 70 kDa protein
AMS64_RS01665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMS64_RS01670	COG3045	CreA protein
AMS64_RS01690	COG0174	glutamine synthetase
AMS64_RS01710	COG3842	ATPase activity
AMS64_RS01715	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMS64_RS01720	COG1177	transmembrane transport
AMS64_RS01725	COG2258	MOSC domain
AMS64_RS01740	COG2050	protein possibly involved in aromatic compounds catabolism
AMS64_RS01745	COG0514	ATP-dependent DNA helicase (RecQ)
AMS64_RS01755	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AMS64_RS01765	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AMS64_RS01770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMS64_RS01785	COG0254	rRNA binding
AMS64_RS01790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AMS64_RS01800	COG0702	epimerase
AMS64_RS01805	COG0814	amino acid
AMS64_RS01810	COG0281	malic enzyme
AMS64_RS01815	COG1295	ribonuclease BN
AMS64_RS01820	COG1490	D-aminoacyl-tRNA deacylase activity
AMS64_RS01825	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AMS64_RS01830	COG0456	acetyltransferase
AMS64_RS01840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMS64_RS01845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMS64_RS01850	COG2610	gluconate transmembrane transporter activity
AMS64_RS01855	COG3265	gluconokinase activity
AMS64_RS01860	COG0129	dihydroxy-acid dehydratase activity
AMS64_RS01865	COG0800	Aldolase
AMS64_RS01870	COG1609	Transcriptional regulator
AMS64_RS01880	COG4942	peptidase
AMS64_RS01885	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AMS64_RS01890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMS64_RS01895	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AMS64_RS01900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMS64_RS01905	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AMS64_RS01905	COG0316	Belongs to the HesB IscA family
AMS64_RS01910	COG1040	competence protein
AMS64_RS01915	COG0596	Alpha beta hydrolase
AMS64_RS01935	COG2183	response to ionizing radiation
AMS64_RS01940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMS64_RS01960	COG0051	transcription antitermination factor activity, RNA binding
AMS64_RS01965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMS64_RS01970	COG0088	Forms part of the polypeptide exit tunnel
AMS64_RS01975	COG0089	rRNA binding
AMS64_RS01980	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMS64_RS01985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMS64_RS01990	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AMS64_RS01995	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMS64_RS02000	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMS64_RS02005	COG0255	Belongs to the universal ribosomal protein uL29 family
AMS64_RS02010	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMS64_RS02015	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AMS64_RS02020	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMS64_RS02025	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMS64_RS02030	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMS64_RS02035	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMS64_RS02040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMS64_RS02045	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMS64_RS02050	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AMS64_RS02055	COG1841	ribosomal large subunit assembly
AMS64_RS02060	COG0200	Binds to the 23S rRNA
AMS64_RS02065	COG0201	protein transport
AMS64_RS02070	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AMS64_RS02075	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AMS64_RS02080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMS64_RS02085	COG0202	RNA polymerase activity
AMS64_RS02090	COG0203	ribosomal protein L17
AMS64_RS02120	COG4771	TonB-dependent receptor
AMS64_RS02125	COG3706	GGDEF domain
AMS64_RS02150	COG0583	DNA-binding transcription factor activity
AMS64_RS02160	COG1741	Belongs to the pirin family
AMS64_RS02165	COG2259	Doxx family
AMS64_RS02170	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AMS64_RS02175	COG1074	ATP-dependent DNA helicase activity
AMS64_RS02180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMS64_RS02220	COG1175	transmembrane transport
AMS64_RS02230	COG3842	ATPase activity
AMS64_RS02260	COG2873	o-acetylhomoserine
AMS64_RS02265	COG4533	DNA binding
AMS64_RS02285	COG5380	lipid catabolic process
AMS64_RS02290	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AMS64_RS02295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMS64_RS02320	COG0753	catalase activity
AMS64_RS02325	COG1247	-acetyltransferase
AMS64_RS02355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMS64_RS02360	COG0795	lipopolysaccharide-transporting ATPase activity
AMS64_RS02365	COG0795	lipopolysaccharide-transporting ATPase activity
AMS64_RS02510	COG4695	Portal protein
AMS64_RS02595	COG4974	Belongs to the 'phage' integrase family
AMS64_RS02600	COG0582	viral genome integration into host DNA
AMS64_RS02670	COG1494	fructose-1,6-bisphosphatase
AMS64_RS02685	COG2959	enzyme of heme biosynthesis
AMS64_RS02695	COG0181	hydroxymethylbilane synthase activity
AMS64_RS02700	COG3072	Adenylate cyclase
AMS64_RS02705	COG0400	carboxylic ester hydrolase activity
AMS64_RS02710	COG1965	Belongs to the frataxin family
AMS64_RS02715	COG0019	diaminopimelate decarboxylase activity
AMS64_RS02720	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMS64_RS02735	COG1011	Hydrolase
AMS64_RS02755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMS64_RS02760	COG3028	Belongs to the UPF0307 family
AMS64_RS02765	COG0312	modulator of DNA gyrase
AMS64_RS02770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMS64_RS02775	COG5007	Belongs to the BolA IbaG family
AMS64_RS02785	COG2854	intermembrane phospholipid transfer
AMS64_RS02790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMS64_RS02795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMS64_RS02800	COG1127	ABC transporter
AMS64_RS02805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AMS64_RS02805	COG0517	IMP dehydrogenase activity
AMS64_RS02810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AMS64_RS02815	COG3117	lipopolysaccharide transmembrane transporter activity
AMS64_RS02820	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AMS64_RS02825	COG1137	ATPase activity
AMS64_RS02840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_RS02845	COG1660	Displays ATPase and GTPase activities
AMS64_RS02850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_RS02855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_RS02855	COG3711	transcriptional antiterminator
AMS64_RS02870	COG3964	amidohydrolase
AMS64_RS02900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMS64_RS02905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMS64_RS02915	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AMS64_RS02920	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMS64_RS02925	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMS64_RS02930	COG0723	plastoquinol--plastocyanin reductase activity
AMS64_RS02935	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMS64_RS02940	COG2857	Cytochrome c1
AMS64_RS02945	COG0625	glutathione transferase activity
AMS64_RS02950	COG2969	positive regulation of protein catabolic process
AMS64_RS02955	COG2823	Periplasmic or secreted lipoprotein
AMS64_RS02960	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMS64_RS02965	COG0792	nuclease activity
AMS64_RS02970	COG3107	peptidoglycan biosynthetic process
AMS64_RS02975	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AMS64_RS03025	COG1987	bacterial-type flagellum assembly
AMS64_RS03050	COG1677	Flagellar hook-basal body complex protein FliE
AMS64_RS03060	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMS64_RS03095	COG1815	bacterial-type flagellum-dependent cell motility
AMS64_RS03115	COG4787	bacterial-type flagellum-dependent cell motility
AMS64_RS03120	COG4786	Flagellar basal body rod
AMS64_RS03125	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AMS64_RS03130	COG1706	bacterial-type flagellum-dependent cell motility
AMS64_RS03140	COG4786	Flagellar basal body rod
AMS64_RS03140	COG1256	bacterial-type flagellum assembly
AMS64_RS03145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMS64_RS03170	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMS64_RS03175	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AMS64_RS03200	COG1191	sigma factor activity
AMS64_RS03205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMS64_RS03215	COG0741	lytic transglycosylase activity
AMS64_RS03215	COG1388	LysM domain
AMS64_RS03225	COG2001	Belongs to the MraZ family
AMS64_RS03230	COG0275	rRNA processing
AMS64_RS03235	COG3116	cell division
AMS64_RS03240	COG0768	penicillin binding
AMS64_RS03250	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AMS64_RS03255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMS64_RS03260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMS64_RS03265	COG0772	Belongs to the SEDS family
AMS64_RS03270	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AMS64_RS03275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMS64_RS03285	COG0849	cell division
AMS64_RS03290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMS64_RS03295	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AMS64_RS03305	COG0653	protein targeting
AMS64_RS03310	COG0494	nUDIX hydrolase
AMS64_RS03315	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AMS64_RS03320	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AMS64_RS03335	COG1459	type II secretion system
AMS64_RS03340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMS64_RS03365	COG2186	Transcriptional regulator
AMS64_RS03370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AMS64_RS03375	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMS64_RS03380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMS64_RS03390	COG0840	transmembrane signaling receptor activity
AMS64_RS03395	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMS64_RS03400	COG1049	propionate catabolic process, 2-methylcitrate cycle
AMS64_RS03415	COG0523	cobalamin synthesis protein
AMS64_RS03420	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_RS03435	COG0477	Major facilitator Superfamily
AMS64_RS03450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AMS64_RS03455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMS64_RS03480	COG3314	Sporulation integral membrane protein YlbJ
AMS64_RS03505	COG0165	Argininosuccinate lyase
AMS64_RS03510	COG0137	argininosuccinate synthase activity
AMS64_RS03520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMS64_RS03525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMS64_RS03535	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AMS64_RS03540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMS64_RS03555	COG0583	DNA-binding transcription factor activity
AMS64_RS03560	COG1380	Effector of murein hydrolase LrgA
AMS64_RS03565	COG1346	cytolysis
AMS64_RS03575	COG4667	esterase of the alpha-beta hydrolase superfamily
AMS64_RS03580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMS64_RS03585	COG1546	Belongs to the CinA family
AMS64_RS03590	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AMS64_RS03600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMS64_RS03605	COG0527	aspartate kinase activity
AMS64_RS03610	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AMS64_RS03635	COG1686	Belongs to the peptidase S11 family
AMS64_RS03640	COG0586	Pfam SNARE associated Golgi protein
AMS64_RS03645	COG1253	flavin adenine dinucleotide binding
AMS64_RS03650	COG0252	asparaginase activity
AMS64_RS03665	COG1609	Transcriptional regulator
AMS64_RS03670	COG1263	PTS System
AMS64_RS03670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_RS03675	COG0366	Alpha amylase catalytic
AMS64_RS03680	COG0110	maltose O-acetyltransferase activity
AMS64_RS03690	COG0564	pseudouridine synthase activity
AMS64_RS03695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMS64_RS03725	COG2926	Belongs to the UPF0265 family
AMS64_RS03735	COG0561	phosphatase activity
AMS64_RS03745	COG1546	Belongs to the CinA family
AMS64_RS03745	COG1058	Belongs to the CinA family
AMS64_RS03755	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AMS64_RS03765	COG1522	sequence-specific DNA binding
AMS64_RS03770	COG1368	sulfuric ester hydrolase activity
AMS64_RS03805	COG4221	oxidoreductase activity
AMS64_RS03820	COG1979	alcohol dehydrogenase
AMS64_RS03825	COG1803	Methylglyoxal synthase
AMS64_RS03850	COG1444	tRNA N-acetyltransferase activity
AMS64_RS03855	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_RS03860	COG0835	chemotaxis
AMS64_RS03860	COG0784	Response regulator, receiver
AMS64_RS03870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AMS64_RS03875	COG2949	membrane
AMS64_RS03880	COG3291	Pkd domain containing protein
AMS64_RS03885	COG0318	PFAM AMP-dependent synthetase and ligase
AMS64_RS03890	COG1441	menaquinone biosynthetic process
AMS64_RS03895	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AMS64_RS03900	COG0596	Alpha beta hydrolase
AMS64_RS03905	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AMS64_RS03910	COG1169	isochorismate synthase
AMS64_RS03915	COG1575	Belongs to the MenA family. Type 1 subfamily
AMS64_RS03935	COG0513	Belongs to the DEAD box helicase family
AMS64_RS03940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMS64_RS03945	COG1988	membrane-bound metal-dependent
AMS64_RS03950	COG1671	Belongs to the UPF0178 family
AMS64_RS03970	COG0484	heat shock protein binding
AMS64_RS03980	COG3722	fumarate hydratase activity
AMS64_RS03985	COG0246	Mannitol dehydrogenase
AMS64_RS03990	COG2213	PTS system mannitol-specific
AMS64_RS03990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_RS03995	COG1560	Kdo2-lipid A biosynthetic process
AMS64_RS04000	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMS64_RS04000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMS64_RS04005	COG1538	Outer membrane efflux protein
AMS64_RS04010	COG0494	nUDIX hydrolase
AMS64_RS04015	COG3151	Protein conserved in bacteria
AMS64_RS04025	COG3150	esterase
AMS64_RS04050	COG3104	oligopeptide transport
AMS64_RS04085	COG0583	DNA-binding transcription factor activity
AMS64_RS04090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMS64_RS04110	COG0204	Acyl-transferase
AMS64_RS04115	COG1842	Phage shock protein A
AMS64_RS04130	COG2827	Endonuclease containing a URI domain
AMS64_RS04145	COG1573	uracil-dna glycosylase
AMS64_RS04150	COG0697	spore germination
AMS64_RS04155	COG0583	DNA-binding transcription factor activity
AMS64_RS04160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMS64_RS04165	COG1121	(ABC) transporter
AMS64_RS04170	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AMS64_RS04190	COG0739	heme binding
AMS64_RS04200	COG3068	Protein conserved in bacteria
AMS64_RS04220	COG0617	tRNA 3'-terminal CCA addition
AMS64_RS04225	COG1194	a g-specific adenine glycosylase
AMS64_RS04230	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AMS64_RS04240	COG3111	PFAM Bacterial OB fold (BOF) protein
AMS64_RS04245	COG3240	lipase activity
AMS64_RS04250	COG2885	chlorophyll binding
AMS64_RS04250	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AMS64_RS04255	COG3706	GGDEF domain
AMS64_RS04260	COG0557	exoribonuclease II activity
AMS64_RS04295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMS64_RS04305	COG2153	protein acetylation
AMS64_RS04310	COG0513	Belongs to the DEAD box helicase family
AMS64_RS04315	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AMS64_RS04345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMS64_RS04350	COG0840	transmembrane signaling receptor activity
AMS64_RS04360	COG4166	transmembrane transport
AMS64_RS04370	COG0110	maltose O-acetyltransferase activity
AMS64_RS04380	COG1024	Enoyl-CoA hydratase
AMS64_RS04395	COG4221	oxidoreductase activity
AMS64_RS04400	COG0442	prolyl-tRNA aminoacylation
AMS64_RS04405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMS64_RS04410	COG3009	Protein conserved in bacteria
AMS64_RS04415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMS64_RS04415	COG3008	intermembrane lipid transfer
AMS64_RS04420	COG2995	paraquat-inducible protein a
AMS64_RS04430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMS64_RS04440	COG4251	negative regulation of phosphorylation
AMS64_RS04440	COG2203	Gaf domain
AMS64_RS04440	COG3706	GGDEF domain
AMS64_RS04440	COG5001	Diguanylate cyclase
AMS64_RS04445	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AMS64_RS04455	COG3916	Acyl-homoserine-lactone synthase
AMS64_RS04460	COG2771	luxR family
AMS64_RS04470	COG0840	transmembrane signaling receptor activity
AMS64_RS04475	COG0632	four-way junction helicase activity
AMS64_RS04480	COG2255	four-way junction helicase activity
AMS64_RS04490	COG1294	oxidase, subunit
AMS64_RS04495	COG4890	Cyd operon protein YbgT
AMS64_RS04505	COG0824	Thioesterase
AMS64_RS04510	COG0811	peptide transport
AMS64_RS04525	COG0823	Involved in the tonB-independent uptake of proteins
AMS64_RS04530	COG2885	chlorophyll binding
AMS64_RS04535	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AMS64_RS04590	COG0733	neurotransmitter:sodium symporter activity
AMS64_RS04600	COG0733	neurotransmitter:sodium symporter activity
AMS64_RS04615	COG0561	phosphatase activity
AMS64_RS04665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMS64_RS04670	COG1640	4-alpha-glucanotransferase
AMS64_RS04675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMS64_RS04680	COG0676	glucose-6-phosphate 1-epimerase activity
AMS64_RS04685	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AMS64_RS04690	COG0840	transmembrane signaling receptor activity
AMS64_RS04695	COG1585	Membrane protein implicated in regulation of membrane protease activity
AMS64_RS04700	COG0330	HflC and HflK could
AMS64_RS04705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMS64_RS04705	COG1648	precorrin-2 dehydrogenase activity
AMS64_RS04710	COG0175	sulfate reduction
AMS64_RS04715	COG2895	sulfate adenylyltransferase (ATP) activity
AMS64_RS04720	COG0471	metal ion transport
AMS64_RS04720	COG3273	potassium ion transport
AMS64_RS04725	COG0529	Catalyzes the synthesis of activated sulfate
AMS64_RS04735	COG0840	transmembrane signaling receptor activity
AMS64_RS04755	COG1136	(ABC) transporter
AMS64_RS04770	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AMS64_RS04785	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMS64_RS04790	COG3437	response regulator, receiver
AMS64_RS04790	COG0784	Response regulator, receiver
AMS64_RS04800	COG2076	Multidrug Resistance protein
AMS64_RS04805	COG2076	Multidrug Resistance protein
AMS64_RS04810	COG0346	lactoylglutathione lyase activity
AMS64_RS04815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMS64_RS04820	COG1643	Atp-dependent helicase
AMS64_RS04830	COG1489	DNA binding
AMS64_RS04835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMS64_RS04840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMS64_RS04850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AMS64_RS04855	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AMS64_RS04860	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AMS64_RS04870	COG1823	symporter activity
AMS64_RS04905	COG0842	Transport permease protein
AMS64_RS04910	COG1131	(ABC) transporter
AMS64_RS04925	COG0163	prenyltransferase activity
AMS64_RS04930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMS64_RS04935	COG0671	phosphoesterase, PA-phosphatase related
AMS64_RS04940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMS64_RS04945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMS64_RS04950	COG1151	hydroxylamine reductase activity
AMS64_RS04955	COG0783	Belongs to the Dps family
AMS64_RS04960	COG3023	N-Acetylmuramoyl-L-alanine amidase
AMS64_RS04965	COG4807	Protein conserved in bacteria
AMS64_RS04975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMS64_RS04980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMS64_RS04985	COG3956	TIGRFAM MazG family protein
AMS64_RS04990	COG0504	CTP synthase activity
AMS64_RS04995	COG0148	phosphopyruvate hydratase activity
AMS64_RS05010	COG2801	Transposase and inactivated derivatives
AMS64_RS05045	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AMS64_RS05055	COG0488	(ABC) transporter
AMS64_RS05075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMS64_RS05090	COG1794	racemase activity, acting on amino acids and derivatives
AMS64_RS05100	COG2731	YhcH YjgK YiaL family protein
AMS64_RS05110	COG0668	transmembrane transport
AMS64_RS05115	COG1376	ErfK ybiS ycfS ynhG family protein
AMS64_RS05125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMS64_RS05130	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AMS64_RS05135	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMS64_RS05145	COG0585	pseudouridine synthase activity
AMS64_RS05150	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AMS64_RS05155	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMS64_RS05160	COG1238	metal cluster binding
AMS64_RS05175	COG1902	pentaerythritol trinitrate reductase activity
AMS64_RS05195	COG2957	Belongs to the agmatine deiminase family
AMS64_RS05200	COG0154	amidase activity
AMS64_RS05255	COG0513	Belongs to the DEAD box helicase family
AMS64_RS05260	COG2199	diguanylate cyclase activity
AMS64_RS05260	COG2203	Gaf domain
AMS64_RS05270	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
AMS64_RS05275	COG1858	cytochrome C peroxidase
AMS64_RS05320	COG2816	NAD+ diphosphatase activity
AMS64_RS05355	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AMS64_RS05370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMS64_RS05375	COG4991	sh3 domain protein
AMS64_RS05385	COG2816	NAD+ diphosphatase activity
AMS64_RS05390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AMS64_RS05395	COG1940	carbohydrate kinase activity
AMS64_RS05400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMS64_RS05405	COG0126	phosphoglycerate kinase activity
AMS64_RS05410	COG0191	fructose-bisphosphate aldolase activity
AMS64_RS05415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_RS05435	COG4232	protein-disulfide reductase activity
AMS64_RS05460	COG0354	folic acid binding
AMS64_RS05465	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AMS64_RS05475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMS64_RS05480	COG1595	DNA-templated transcription, initiation
AMS64_RS05485	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AMS64_RS05490	COG3026	antisigma factor binding
AMS64_RS05500	COG0481	GTPase activity
AMS64_RS05505	COG0681	Belongs to the peptidase S26 family
AMS64_RS05520	COG1381	Involved in DNA repair and RecF pathway recombination
AMS64_RS05525	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMS64_RS05535	COG2350	Protein conserved in bacteria
AMS64_RS05540	COG2917	probably involved in intracellular septation
AMS64_RS05545	COG0076	glutamate decarboxylase activity
AMS64_RS05550	COG1272	protein, Hemolysin III
AMS64_RS05555	COG2985	domain, Protein
AMS64_RS05555	COG0569	domain protein
AMS64_RS05575	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AMS64_RS05610	COG4974	Belongs to the 'phage' integrase family
AMS64_RS05615	COG3541	Predicted nucleotidyltransferase
AMS64_RS05635	COG0582	viral genome integration into host DNA
AMS64_RS05660	COG2313	pseudouridylate synthase activity
AMS64_RS05665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMS64_RS05705	COG1765	OsmC-like protein
AMS64_RS05720	COG3954	Phosphoribulokinase
AMS64_RS05725	COG3089	Belongs to the UPF0270 family
AMS64_RS05730	COG5001	Diguanylate cyclase
AMS64_RS05730	COG3706	GGDEF domain
AMS64_RS05730	COG2203	Gaf domain
AMS64_RS05730	COG4251	negative regulation of phosphorylation
AMS64_RS05735	COG0429	hydrolase of the alpha beta-hydrolase fold
AMS64_RS05740	COG0784	Response regulator, receiver
AMS64_RS05740	COG0835	chemotaxis
AMS64_RS05750	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AMS64_RS05755	COG1047	Peptidyl-prolyl cis-trans
AMS64_RS05760	COG2900	Belongs to the SlyX family
AMS64_RS05770	COG0545	Peptidyl-prolyl cis-trans isomerase
AMS64_RS05775	COG2204	response regulator
AMS64_RS05795	COG0737	Belongs to the 5'-nucleotidase family
AMS64_RS05815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMS64_RS05840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMS64_RS05850	COG3721	Heme iron utilization protein
AMS64_RS05855	COG0748	coenzyme F420 binding
AMS64_RS05890	COG3501	Rhs element vgr protein
AMS64_RS05905	COG2814	Major facilitator Superfamily
AMS64_RS05915	COG3655	Transcriptional regulator
AMS64_RS05925	COG2205	protein histidine kinase activity
AMS64_RS05925	COG5002	protein histidine kinase activity
AMS64_RS05925	COG0784	Response regulator, receiver
AMS64_RS05940	COG3706	GGDEF domain
AMS64_RS05955	COG3397	chitin binding
AMS64_RS05995	COG0835	chemotaxis
AMS64_RS05995	COG0784	Response regulator, receiver
AMS64_RS06000	COG2755	lipolytic protein G-D-S-L family
AMS64_RS06005	COG4181	ATPase activity
AMS64_RS06010	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AMS64_RS06015	COG1090	epimerase
AMS64_RS06020	COG2200	EAL domain
AMS64_RS06025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMS64_RS06030	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMS64_RS06035	COG3171	Protein conserved in bacteria
AMS64_RS06040	COG2066	Belongs to the glutaminase family
AMS64_RS06045	COG2897	thiosulfate sulfurtransferase activity
AMS64_RS06060	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMS64_RS06070	COG2966	Psort location CytoplasmicMembrane, score
AMS64_RS06075	COG3610	response to peptide
AMS64_RS06090	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMS64_RS06095	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMS64_RS06105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMS64_RS06110	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMS64_RS06120	COG0786	glutamate:sodium symporter activity
AMS64_RS06125	COG0252	asparaginase activity
AMS64_RS06130	COG3139	Protein of unknown function (DUF1315)
AMS64_RS06180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMS64_RS06185	COG0321	lipoyl(octanoyl) transferase activity
AMS64_RS06190	COG2921	Belongs to the UPF0250 family
AMS64_RS06195	COG1686	Belongs to the peptidase S11 family
AMS64_RS06200	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMS64_RS06205	COG2951	lytic endotransglycosylase activity
AMS64_RS06210	COG0772	Belongs to the SEDS family
AMS64_RS06215	COG0768	penicillin binding
AMS64_RS06220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMS64_RS06225	COG0799	negative regulation of ribosome biogenesis
AMS64_RS06230	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMS64_RS06245	COG0495	leucyl-tRNA aminoacylation
AMS64_RS06250	COG2888	peptidyl-tyrosine sulfation
AMS64_RS06255	COG0312	modulator of DNA gyrase
AMS64_RS06265	COG0716	FMN binding
AMS64_RS06270	COG4974	Belongs to the 'phage' integrase family
AMS64_RS06280	COG1970	mechanosensitive ion channel activity
AMS64_RS06295	COG0789	Transcriptional regulator
AMS64_RS06305	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMS64_RS06310	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AMS64_RS06315	COG4535	Mg2 and Co2 transporter CorC
AMS64_RS06320	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMS64_RS06325	COG1702	phosphate starvation-inducible protein PhoH
AMS64_RS06330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMS64_RS06335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMS64_RS06340	COG1335	isochorismatase
AMS64_RS06350	COG3706	GGDEF domain
AMS64_RS06355	COG0583	DNA-binding transcription factor activity
AMS64_RS06375	COG3706	GGDEF domain
AMS64_RS06385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMS64_RS06395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMS64_RS06405	COG0516	GMP reductase activity
AMS64_RS06425	COG0642	Histidine kinase
AMS64_RS06440	COG4221	oxidoreductase activity
AMS64_RS06450	COG1022	Amp-dependent synthetase and ligase
AMS64_RS06465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_RS06480	COG3214	Protein conserved in bacteria
AMS64_RS06490	COG2195	Cleaves the N-terminal amino acid of tripeptides
AMS64_RS06495	COG0700	Nucleoside recognition
AMS64_RS06500	COG3366	ferrous iron transmembrane transporter activity
AMS64_RS06505	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AMS64_RS06510	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AMS64_RS06515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMS64_RS06520	COG1053	succinate dehydrogenase
AMS64_RS06530	COG0584	glycerophosphoryl diester phosphodiesterase
AMS64_RS06535	COG1511	domain protein
AMS64_RS06535	COG3264	Mechanosensitive ion channel
AMS64_RS06545	COG0739	heme binding
AMS64_RS06555	COG0583	DNA-binding transcription factor activity
AMS64_RS06575	COG0583	DNA-binding transcription factor activity
AMS64_RS06580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMS64_RS06610	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMS64_RS06615	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMS64_RS06625	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AMS64_RS06630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AMS64_RS06640	COG0180	Tryptophanyl-tRNA synthetase
AMS64_RS06650	COG0512	Glutamine amidotransferase of anthranilate synthase
AMS64_RS06655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMS64_RS06665	COG1012	belongs to the aldehyde dehydrogenase family
AMS64_RS06680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMS64_RS06685	COG2814	Major facilitator Superfamily
AMS64_RS06690	COG0366	Alpha amylase catalytic
AMS64_RS06700	COG0443	Heat shock 70 kDa protein
AMS64_RS06715	COG0657	acetylesterase activity
AMS64_RS06730	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AMS64_RS06740	COG0490	domain, Protein
AMS64_RS06740	COG0471	metal ion transport
AMS64_RS06795	COG0012	GTP binding
AMS64_RS06800	COG0193	aminoacyl-tRNA hydrolase activity
AMS64_RS06805	COG0737	Belongs to the 5'-nucleotidase family
AMS64_RS06810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMS64_RS06820	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMS64_RS06825	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AMS64_RS06830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMS64_RS06835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMS64_RS06840	COG2890	protein-(glutamine-N5) methyltransferase activity
AMS64_RS06850	COG2912	Transglutaminase-like superfamily
AMS64_RS06855	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AMS64_RS06860	COG1301	dicarboxylic acid transport
AMS64_RS06875	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMS64_RS06885	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AMS64_RS06885	COG3408	Glycogen debranching enzyme
AMS64_RS06895	COG1881	PFAM PEBP family protein
AMS64_RS06900	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMS64_RS06915	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMS64_RS06925	COG0583	DNA-binding transcription factor activity
AMS64_RS06930	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_RS06935	COG0616	signal peptide processing
AMS64_RS06940	COG2211	Major facilitator Superfamily
AMS64_RS06945	COG3706	GGDEF domain
AMS64_RS06950	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AMS64_RS06960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMS64_RS06965	COG0826	peptidase U32
AMS64_RS06990	COG3724	N-succinylarginine dihydrolase activity
AMS64_RS07005	COG0840	transmembrane signaling receptor activity
AMS64_RS07015	COG2971	BadF BadG BcrA BcrD
AMS64_RS07025	COG4608	Belongs to the ABC transporter superfamily
AMS64_RS07030	COG0444	Belongs to the ABC transporter superfamily
AMS64_RS07035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMS64_RS07050	COG2205	protein histidine kinase activity
AMS64_RS07050	COG0784	Response regulator, receiver
AMS64_RS07080	COG3220	belongs to the UPF0276 family
AMS64_RS07110	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMS64_RS07115	COG1289	transmembrane transporter activity
AMS64_RS07120	COG0303	'Molybdopterin
AMS64_RS07125	COG0746	molybdenum cofactor guanylyltransferase activity
AMS64_RS07135	COG4662	Binding-protein-dependent transport system inner membrane component
AMS64_RS07145	COG2204	response regulator
AMS64_RS07150	COG3852	Histidine kinase
AMS64_RS07160	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMS64_RS07190	COG3383	formate dehydrogenase (NAD+) activity
AMS64_RS07190	COG3383	formate dehydrogenase (NAD+) activity
AMS64_RS07195	COG0437	4 iron, 4 sulfur cluster binding
AMS64_RS07215	COG0281	malic enzyme
AMS64_RS07235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_RS07265	COG0837	glucose binding
AMS64_RS07270	COG1737	Transcriptional regulator
AMS64_RS07275	COG0469	pyruvate kinase activity
AMS64_RS07295	COG1677	Flagellar hook-basal body complex protein FliE
AMS64_RS07305	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMS64_RS07360	COG1684	flagellar biosynthetic protein fliR
AMS64_RS07370	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMS64_RS07395	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AMS64_RS07400	COG2198	Histidine kinase
AMS64_RS07400	COG0784	Response regulator, receiver
AMS64_RS07400	COG0643	Histidine kinase
AMS64_RS07405	COG2201	protein-glutamate methylesterase activity
AMS64_RS07410	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMS64_RS07415	COG1360	Flagellar Motor Protein
AMS64_RS07420	COG1192	Involved in chromosome partitioning
AMS64_RS07430	COG0835	chemotaxis
AMS64_RS07445	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMS64_RS07450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMS64_RS07455	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMS64_RS07460	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AMS64_RS07465	COG1138	Cytochrome C-type biogenesis protein
AMS64_RS07470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMS64_RS07475	COG4235	cytochrome complex assembly
AMS64_RS07475	COG3088	subunit of a heme lyase
AMS64_RS07485	COG2853	Lipoprotein
AMS64_RS07495	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AMS64_RS07500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMS64_RS07510	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMS64_RS07515	COG1882	Formate acetyltransferase
AMS64_RS07525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMS64_RS07525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMS64_RS07570	COG0259	pyridoxamine-phosphate oxidase activity
AMS64_RS07575	COG0625	glutathione transferase activity
AMS64_RS07595	COG2850	peptidyl-arginine hydroxylation
AMS64_RS07600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMS64_RS07605	COG2915	High frequency lysogenization protein hflD homolog
AMS64_RS07610	COG0482	sulfurtransferase activity
AMS64_RS07620	COG1187	pseudouridine synthase activity
AMS64_RS07630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_RS07640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_RS07640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_RS07640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_RS07660	COG1609	Transcriptional regulator
AMS64_RS07665	COG1263	PTS System
AMS64_RS07665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_RS07670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMS64_RS07695	COG4792	protein secretion
AMS64_RS07700	COG4791	protein targeting
AMS64_RS07705	COG4794	Type iii secretion
AMS64_RS07710	COG4790	Type iii secretion
AMS64_RS07755	COG0457	Tetratricopeptide repeat
AMS64_RS07780	COG0457	Tetratricopeptide repeat
AMS64_RS07870	COG1317	bacterial-type flagellum organization
AMS64_RS07950	COG0582	viral genome integration into host DNA
AMS64_RS07955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMS64_RS07960	COG0326	Molecular chaperone. Has ATPase activity
AMS64_RS07965	COG4172	Belongs to the ABC transporter superfamily
AMS64_RS07970	COG4172	Belongs to the ABC transporter superfamily
AMS64_RS07980	COG4168	peptide transport system, permease
AMS64_RS07985	COG0747	negative chemotaxis
AMS64_RS07990	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AMS64_RS07995	COG1842	Phage shock protein A
AMS64_RS08010	COG3106	COG3106 Predicted ATPase
AMS64_RS08015	COG3768	UPF0283 membrane protein
AMS64_RS08025	COG2154	pterin-4-alpha-carbinolamine dehydratase
AMS64_RS08040	COG2199	diguanylate cyclase activity
AMS64_RS08045	COG2885	chlorophyll binding
AMS64_RS08050	COG0861	Integral membrane protein TerC family
AMS64_RS08085	COG2910	NAD(P)H-binding
AMS64_RS08090	COG0583	DNA-binding transcription factor activity
AMS64_RS08100	COG4977	sequence-specific DNA binding
AMS64_RS08105	COG4774	siderophore transport
AMS64_RS08115	COG0583	DNA-binding transcription factor activity
AMS64_RS08120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AMS64_RS08130	COG0583	DNA-binding transcription factor activity
AMS64_RS08135	COG2723	6-phospho-beta-galactosidase activity
AMS64_RS08140	COG1944	ATP diphosphatase activity
AMS64_RS08145	COG2116	formate transmembrane transporter activity
AMS64_RS08150	COG1882	Formate acetyltransferase
AMS64_RS08160	COG2983	Belongs to the UPF0260 family
AMS64_RS08175	COG0058	SHG alpha-glucan phosphorylase activity
AMS64_RS08180	COG0471	metal ion transport
AMS64_RS08185	COG3118	belongs to the thioredoxin family
AMS64_RS08195	COG1132	(ABC) transporter
AMS64_RS08200	COG1132	(ABC) transporter
AMS64_RS08210	COG2501	S4 domain
AMS64_RS08225	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AMS64_RS08265	COG2009	succinate dehydrogenase
AMS64_RS08270	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AMS64_RS08275	COG1053	succinate dehydrogenase
AMS64_RS08285	COG0567	Dehydrogenase, E1 component
AMS64_RS08290	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMS64_RS08295	COG0045	succinate-CoA ligase (ADP-forming) activity
AMS64_RS08305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_RS08315	COG3842	ATPase activity
AMS64_RS08330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AMS64_RS08335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMS64_RS08340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMS64_RS08355	COG4235	cytochrome complex assembly
AMS64_RS08355	COG3088	subunit of a heme lyase
AMS64_RS08365	COG1138	Cytochrome C-type biogenesis protein
AMS64_RS08370	COG3301	Polysulphide reductase, NrfD
AMS64_RS08375	COG0437	4 iron, 4 sulfur cluster binding
AMS64_RS08380	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AMS64_RS08395	COG0247	lactate metabolic process
AMS64_RS08400	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AMS64_RS08405	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AMS64_RS08410	COG3012	SEC-C Motif Domain Protein
AMS64_RS08415	COG0840	transmembrane signaling receptor activity
AMS64_RS08420	COG1846	Transcriptional regulator
AMS64_RS08420	COG1940	carbohydrate kinase activity
AMS64_RS08425	COG3148	PFAM DTW domain containing protein
AMS64_RS08430	COG0730	response to heat
AMS64_RS08435	COG0583	DNA-binding transcription factor activity
AMS64_RS08450	COG3593	DNA synthesis involved in DNA repair
AMS64_RS08485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMS64_RS08490	COG1011	Hydrolase
AMS64_RS08505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMS64_RS08510	COG2832	Protein of unknown function (DUF454)
AMS64_RS08515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMS64_RS08520	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AMS64_RS08525	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMS64_RS08530	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AMS64_RS08545	COG1560	Kdo2-lipid A biosynthetic process
AMS64_RS08550	COG1560	Kdo2-lipid A biosynthetic process
AMS64_RS08565	COG2203	Gaf domain
AMS64_RS08565	COG2199	diguanylate cyclase activity
AMS64_RS08575	COG0417	DNA replication proofreading
AMS64_RS08590	COG1451	nucleotide metabolic process
AMS64_RS08605	COG3069	C4-dicarboxylate transmembrane transporter activity
AMS64_RS08620	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AMS64_RS08620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_RS08625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMS64_RS08630	COG2985	domain, Protein
AMS64_RS08630	COG0569	domain protein
AMS64_RS08640	COG0556	nucleotide-excision repair
AMS64_RS08650	COG0586	Pfam SNARE associated Golgi protein
AMS64_RS08655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AMS64_RS08660	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMS64_RS08670	COG4681	YaeQ
AMS64_RS08725	COG3829	transcription factor binding
AMS64_RS08770	COG0307	riboflavin synthase, alpha
AMS64_RS08780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMS64_RS08785	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AMS64_RS08790	COG0697	spore germination
AMS64_RS08795	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AMS64_RS08835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMS64_RS08840	COG3099	Belongs to the UPF0263 family
AMS64_RS08845	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AMS64_RS08850	COG2894	cell division
AMS64_RS08855	COG0850	regulation of cytokinetic process
AMS64_RS08860	COG3100	YcgL domain-containing protein
AMS64_RS08865	COG1760	l-serine dehydratase
AMS64_RS08870	COG1760	l-serine dehydratase
AMS64_RS08875	COG3123	guanosine phosphorylase activity
AMS64_RS08880	COG1301	dicarboxylic acid transport
AMS64_RS08885	COG0205	6-phosphofructokinase activity
AMS64_RS08895	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AMS64_RS08900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMS64_RS08910	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AMS64_RS08915	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AMS64_RS08920	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMS64_RS08955	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMS64_RS08960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMS64_RS08965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMS64_RS08975	COG0549	Belongs to the carbamate kinase family
AMS64_RS08980	COG0697	spore germination
AMS64_RS08990	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AMS64_RS08990	COG3608	succinylglutamate desuccinylase aspartoacylase
AMS64_RS08995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMS64_RS09000	COG2068	MobA-Related Protein
AMS64_RS09005	COG0493	'glutamate synthase
AMS64_RS09005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMS64_RS09010	COG0402	S-adenosylhomocysteine deaminase activity
AMS64_RS09015	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMS64_RS09020	COG2080	2 iron, 2 sulfur cluster binding
AMS64_RS09020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMS64_RS09025	COG2233	PERMEase
AMS64_RS09030	COG0402	S-adenosylhomocysteine deaminase activity
AMS64_RS09035	COG2252	PERMEase
AMS64_RS09045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMS64_RS09050	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMS64_RS09055	COG2080	2 iron, 2 sulfur cluster binding
AMS64_RS09060	COG3134	Outer membrane lipoprotein
AMS64_RS09070	COG1288	antiporter activity
AMS64_RS09075	COG0318	PFAM AMP-dependent synthetase and ligase
AMS64_RS09080	COG2199	diguanylate cyclase activity
AMS64_RS09090	COG2801	Transposase and inactivated derivatives
AMS64_RS09100	COG0107	imidazoleglycerol-phosphate synthase activity
AMS64_RS09105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AMS64_RS09110	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMS64_RS09115	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMS64_RS09115	COG0131	Imidazoleglycerol-phosphate dehydratase
AMS64_RS09120	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMS64_RS09125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMS64_RS09130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMS64_RS09140	COG1199	ATP-dependent helicase activity
AMS64_RS09145	COG1214	PFAM Peptidase M22, glycoprotease
AMS64_RS09155	COG2267	carboxylic ester hydrolase activity
AMS64_RS09160	COG0318	PFAM AMP-dependent synthetase and ligase
AMS64_RS09170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMS64_RS09175	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AMS64_RS09180	COG0709	Synthesizes selenophosphate from selenide and ATP
AMS64_RS09190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMS64_RS09195	COG0840	transmembrane signaling receptor activity
AMS64_RS09200	COG1254	Belongs to the acylphosphatase family
AMS64_RS09210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMS64_RS09210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMS64_RS09215	COG0489	protein tyrosine kinase activity
AMS64_RS09220	COG0572	uridine kinase
AMS64_RS09225	COG0717	Belongs to the dCTP deaminase family
AMS64_RS09230	COG0306	phosphate transporter
AMS64_RS09235	COG2140	Oxalate decarboxylase
AMS64_RS09240	COG1609	Transcriptional regulator
AMS64_RS09255	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_RS09255	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_RS09260	COG3715	PTS system
AMS64_RS09265	COG3716	PTS system mannose fructose sorbose family IID component
AMS64_RS09270	COG2942	2-epimerase
AMS64_RS09275	COG3313	Fe-S protein
AMS64_RS09280	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AMS64_RS09285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMS64_RS09290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMS64_RS09295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMS64_RS09305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMS64_RS09315	COG0366	Alpha amylase catalytic
AMS64_RS09330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMS64_RS09335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMS64_RS09340	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AMS64_RS09345	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMS64_RS09350	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMS64_RS09355	COG0072	phenylalanine-tRNA ligase activity
AMS64_RS09355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMS64_RS09360	COG0776	regulation of translation
AMS64_RS09365	COG2205	protein histidine kinase activity
AMS64_RS09365	COG0784	Response regulator, receiver
AMS64_RS09390	COG3300	MHYT domain
AMS64_RS09390	COG5001	Diguanylate cyclase
AMS64_RS09395	COG1609	Transcriptional regulator
AMS64_RS09400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMS64_RS09405	COG1879	ABC-type sugar transport system periplasmic component
AMS64_RS09410	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMS64_RS09415	COG1129	ABC transporter
AMS64_RS09420	COG1869	D-ribose catabolic process
AMS64_RS09425	COG0625	glutathione transferase activity
AMS64_RS09440	COG1177	transmembrane transport
AMS64_RS09465	COG0037	tRNA processing
AMS64_RS09470	COG0589	response to stress
AMS64_RS09475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMS64_RS09490	COG2217	Heavy metal translocating P-type atpase
AMS64_RS09500	COG2010	Cytochrome c
AMS64_RS09515	COG3278	Belongs to the heme-copper respiratory oxidase family
AMS64_RS09525	COG1956	GAF domain-containing protein
AMS64_RS09530	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AMS64_RS09540	COG0308	aminopeptidase N
AMS64_RS09550	COG2902	Dehydrogenase
AMS64_RS09555	COG0167	dihydroorotate dehydrogenase activity
AMS64_RS09565	COG0254	rRNA binding
AMS64_RS09570	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMS64_RS09575	COG0116	Belongs to the methyltransferase superfamily
AMS64_RS09575	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMS64_RS09585	COG0488	(ABC) transporter
AMS64_RS09590	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMS64_RS09595	COG1067	ATP-dependent peptidase activity
AMS64_RS09605	COG1598	PFAM Uncharacterised protein family UPF0150
AMS64_RS09610	COG4128	Pfam Zonular occludens toxin
AMS64_RS09645	COG2932	Transcriptional regulator
AMS64_RS09675	COG3141	response to X-ray
AMS64_RS09680	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AMS64_RS09685	COG4221	oxidoreductase activity
AMS64_RS09730	COG0372	Belongs to the citrate synthase family
AMS64_RS09735	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AMS64_RS09745	COG2995	paraquat-inducible protein a
AMS64_RS09750	COG3008	intermembrane lipid transfer
AMS64_RS09755	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AMS64_RS09755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMS64_RS09765	COG2801	Transposase and inactivated derivatives
AMS64_RS09775	COG3093	addiction module antidote protein HigA
AMS64_RS09795	COG0084	hydrolase, TatD family'
AMS64_RS09800	COG0470	DNA polymerase III
AMS64_RS09805	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMS64_RS09810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMS64_RS09815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMS64_RS09820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMS64_RS09825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMS64_RS09830	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_RS09840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMS64_RS09845	COG0416	fatty acid biosynthetic process
AMS64_RS09850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMS64_RS09855	COG1399	metal-binding, possibly nucleic acid-binding protein
AMS64_RS09860	COG0424	maF-like protein
AMS64_RS09875	COG1530	ribonuclease E activity
AMS64_RS09880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_RS09880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_RS09880	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AMS64_RS09885	COG1105	Belongs to the carbohydrate kinase PfkB family
AMS64_RS09890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_RS09890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_RS09895	COG1609	Transcriptional regulator
AMS64_RS09900	COG0814	amino acid
AMS64_RS09910	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AMS64_RS09920	COG0513	Belongs to the DEAD box helicase family
AMS64_RS09930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMS64_RS09935	COG2890	protein-(glutamine-N5) methyltransferase activity
AMS64_RS09940	COG2840	Smr protein MutS2
AMS64_RS09945	COG3706	GGDEF domain
AMS64_RS09950	COG0406	alpha-ribazole phosphatase activity
AMS64_RS09965	COG2824	Alkylphosphonate utilization operon protein PhnA
AMS64_RS09980	COG0494	nUDIX hydrolase
AMS64_RS09985	COG0814	amino acid
AMS64_RS09995	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AMS64_RS10000	COG0514	ATP-dependent DNA helicase (RecQ)
AMS64_RS10005	COG2766	serine protein kinase
AMS64_RS10010	COG2718	Belongs to the UPF0229 family
AMS64_RS10015	COG2719	SpoVR family
AMS64_RS10020	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMS64_RS10020	COG1024	Enoyl-CoA hydratase
AMS64_RS10025	COG0183	Belongs to the thiolase family
AMS64_RS10030	COG0714	Associated with various cellular activities
AMS64_RS10050	COG2304	oxidoreductase activity
AMS64_RS10060	COG1595	DNA-templated transcription, initiation
AMS64_RS10070	COG2067	long-chain fatty acid transport protein
AMS64_RS10075	COG2067	long-chain fatty acid transport protein
AMS64_RS10080	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AMS64_RS10095	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AMS64_RS10105	COG1643	Atp-dependent helicase
AMS64_RS10110	COG0617	tRNA 3'-terminal CCA addition
AMS64_RS10110	COG0517	IMP dehydrogenase activity
AMS64_RS10110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AMS64_RS10120	COG3119	arylsulfatase activity
AMS64_RS10125	COG0714	Associated with various cellular activities
AMS64_RS10145	COG2304	oxidoreductase activity
AMS64_RS10170	COG0641	radical SAM
AMS64_RS10175	COG2925	Exonuclease
AMS64_RS10185	COG3345	alpha-galactosidase
AMS64_RS10190	COG1380	Effector of murein hydrolase LrgA
AMS64_RS10195	COG1346	cytolysis
AMS64_RS10200	COG0295	cytidine deaminase activity
AMS64_RS10205	COG3033	Beta-eliminating lyase
AMS64_RS10210	COG3046	protein related to deoxyribodipyrimidine photolyase
AMS64_RS10215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_RS10220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMS64_RS10240	COG3383	formate dehydrogenase (NAD+) activity
AMS64_RS10245	COG3383	formate dehydrogenase (NAD+) activity
AMS64_RS10250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMS64_RS10260	COG3158	transport of potassium into the cell
AMS64_RS10265	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMS64_RS10270	COG0651	ATP synthesis coupled electron transport
AMS64_RS10275	COG0650	Formate hydrogenlyase subunit 4
AMS64_RS10280	COG3261	NADH dehydrogenase
AMS64_RS10280	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AMS64_RS10285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_RS10290	COG3260	NADH ubiquinone oxidoreductase 20
AMS64_RS10300	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AMS64_RS10305	COG1921	L-seryl-tRNASec selenium transferase activity
AMS64_RS10315	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AMS64_RS10320	COG0298	carbon dioxide binding
AMS64_RS10330	COG0309	Hydrogenase expression formation protein (HypE)
AMS64_RS10335	COG0375	protein maturation
AMS64_RS10340	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AMS64_RS10350	COG3842	ATPase activity
AMS64_RS10355	COG0444	Belongs to the ABC transporter superfamily
AMS64_RS10360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMS64_RS10365	COG0601	transmembrane transport
AMS64_RS10375	COG1773	rubredoxin
AMS64_RS10380	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AMS64_RS10385	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AMS64_RS10390	COG5557	Pfam Polysulphide reductase, NrfD
AMS64_RS10395	COG0437	4 iron, 4 sulfur cluster binding
AMS64_RS10400	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AMS64_RS10410	COG0438	transferase activity, transferring glycosyl groups
AMS64_RS10415	COG0438	transferase activity, transferring glycosyl groups
AMS64_RS10435	COG0438	transferase activity, transferring glycosyl groups
AMS64_RS10475	COG0438	transferase activity, transferring glycosyl groups
AMS64_RS10480	COG1215	transferase activity, transferring glycosyl groups
AMS64_RS10485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMS64_RS10525	COG0784	Response regulator, receiver
AMS64_RS10525	COG2205	protein histidine kinase activity
AMS64_RS10565	COG5489	Protein of unknown function (DUF736)
AMS64_RS10595	COG0658	competence protein
AMS64_RS10595	COG2333	competence protein COMEC
AMS64_RS10650	COG3409	Peptidoglycan-binding domain 1 protein
AMS64_RS10650	COG3267	Type II secretory pathway component ExeA
AMS64_RS10670	COG0730	response to heat
AMS64_RS10680	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_RS10690	COG1024	Enoyl-CoA hydratase
AMS64_RS10695	COG1024	Enoyl-CoA hydratase
AMS64_RS10700	COG1960	acyl-CoA dehydrogenase activity
AMS64_RS10705	COG1960	acyl-CoA dehydrogenase activity
AMS64_RS10710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMS64_RS10715	COG1024	Enoyl-CoA hydratase
AMS64_RS10745	COG1584	GPR1 FUN34 yaaH family protein
AMS64_RS10765	COG1115	amino acid carrier protein
AMS64_RS10790	COG4695	Portal protein
AMS64_RS10795	COG1024	Enoyl-CoA hydratase
AMS64_RS10810	COG3162	membrane
AMS64_RS10815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMS64_RS10840	COG0582	viral genome integration into host DNA
AMS64_RS10845	COG0488	(ABC) transporter
AMS64_RS10850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMS64_RS10855	COG0776	regulation of translation
AMS64_RS10860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMS64_RS10865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMS64_RS10870	COG0740	serine-type endopeptidase activity
AMS64_RS10875	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMS64_RS10885	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AMS64_RS10890	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMS64_RS10895	COG1136	(ABC) transporter
AMS64_RS10900	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMS64_RS10910	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMS64_RS10915	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AMS64_RS10920	COG4166	transmembrane transport
AMS64_RS10925	COG0697	spore germination
AMS64_RS10935	COG2062	phosphohistidine phosphatase, SixA
AMS64_RS10940	COG1025	Belongs to the peptidase M16 family
AMS64_RS10970	COG0519	Catalyzes the synthesis of GMP from XMP
AMS64_RS10970	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMS64_RS10975	COG0517	IMP dehydrogenase activity
AMS64_RS10975	COG0516	GMP reductase activity
AMS64_RS10980	COG3038	cytochrome b561
AMS64_RS10985	COG1570	exodeoxyribonuclease VII activity
AMS64_RS10990	COG2188	Transcriptional regulator
AMS64_RS10995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_RS10995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_RS10995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_RS11000	COG0383	alpha-mannosidase activity
AMS64_RS11005	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMS64_RS11015	COG0386	Belongs to the glutathione peroxidase family
AMS64_RS11020	COG0513	Belongs to the DEAD box helicase family
AMS64_RS11035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMS64_RS11040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMS64_RS11045	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AMS64_RS11095	COG3300	MHYT domain
AMS64_RS11095	COG5001	Diguanylate cyclase
AMS64_RS11110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMS64_RS11120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMS64_RS11125	COG0563	adenylate kinase activity
AMS64_RS11135	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AMS64_RS11140	COG1286	toxin biosynthetic process
AMS64_RS11145	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMS64_RS11150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMS64_RS11155	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AMS64_RS11160	COG0531	amino acid
AMS64_RS11160	COG1674	ftsk spoiiie
AMS64_RS11170	COG0686	Belongs to the AlaDH PNT family
AMS64_RS11175	COG0492	ferredoxin-NADP+ reductase activity
AMS64_RS11180	COG3706	GGDEF domain
AMS64_RS11185	COG3134	Outer membrane lipoprotein
AMS64_RS11190	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AMS64_RS11195	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AMS64_RS11200	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMS64_RS11205	COG0542	response to heat
AMS64_RS11210	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AMS64_RS11215	COG1278	Cold shock
AMS64_RS11220	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMS64_RS11245	COG2205	protein histidine kinase activity
AMS64_RS11255	COG0392	lysyltransferase activity
AMS64_RS11255	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AMS64_RS11265	COG3501	Rhs element vgr protein
AMS64_RS11295	COG3829	transcription factor binding
AMS64_RS11390	COG0672	)-iron permease
AMS64_RS11410	COG2814	Major facilitator Superfamily
AMS64_RS11425	COG1136	(ABC) transporter
AMS64_RS11430	COG0577	efflux transmembrane transporter activity
AMS64_RS11445	COG0596	Alpha beta hydrolase
AMS64_RS11465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMS64_RS11470	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AMS64_RS11470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMS64_RS11475	COG0527	aspartate kinase activity
AMS64_RS11485	COG1368	sulfuric ester hydrolase activity
AMS64_RS11490	COG1619	proteins homologs of microcin C7 resistance protein MccF
AMS64_RS11495	COG4667	esterase of the alpha-beta hydrolase superfamily
AMS64_RS11515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMS64_RS11515	COG1648	precorrin-2 dehydrogenase activity
AMS64_RS11525	COG0393	Putative heavy-metal-binding
AMS64_RS11530	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AMS64_RS11535	COG0285	dihydrofolate synthase activity
AMS64_RS11540	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AMS64_RS11545	COG0101	tRNA pseudouridine synthase activity
AMS64_RS11555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMS64_RS11560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMS64_RS11565	COG0671	phosphoesterase, PA-phosphatase related
AMS64_RS11570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMS64_RS11575	COG2056	Na+-H+ antiporter family
AMS64_RS11580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMS64_RS11580	COG0047	phosphoribosylformylglycinamidine synthase activity
AMS64_RS11585	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AMS64_RS11590	COG1645	bacterial-type flagellum-dependent swarming motility
AMS64_RS11595	COG1160	GTP binding
AMS64_RS11600	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMS64_RS11605	COG2976	Protein conserved in bacteria
AMS64_RS11610	COG0124	histidyl-tRNA synthetase
AMS64_RS11615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AMS64_RS11630	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMS64_RS11635	COG0105	UTP biosynthetic process
AMS64_RS11650	COG0633	Ferredoxin
AMS64_RS11655	COG0443	Heat shock 70 kDa protein
AMS64_RS11660	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMS64_RS11670	COG0822	iron-sulfur transferase activity
AMS64_RS11675	COG1104	cysteine desulfurase activity
AMS64_RS11695	COG3154	lipid carrier protein
AMS64_RS11700	COG0826	peptidase U32
AMS64_RS11705	COG0826	peptidase U32
AMS64_RS11720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMS64_RS11725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMS64_RS11730	COG1862	Preprotein translocase
AMS64_RS11735	COG0343	queuine tRNA-ribosyltransferase activity
AMS64_RS11740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AMS64_RS11745	COG0517	IMP dehydrogenase activity
AMS64_RS11755	COG3634	alkyl hydroperoxide reductase activity
AMS64_RS11810	COG1242	4 iron, 4 sulfur cluster binding
AMS64_RS11820	COG0067	glutamate synthase
AMS64_RS11820	COG0069	glutamate synthase activity
AMS64_RS11820	COG0070	glutamate synthase
AMS64_RS11825	COG0493	'glutamate synthase
AMS64_RS11835	COG0513	Belongs to the DEAD box helicase family
AMS64_RS11860	COG0023	Translation Initiation Factor
AMS64_RS11865	COG2119	membrane
AMS64_RS11905	COG0215	cysteine-tRNA ligase activity
AMS64_RS11910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMS64_RS11920	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMS64_RS11930	COG2261	transglycosylase associated protein
AMS64_RS11935	COG0642	Histidine kinase
AMS64_RS12005	COG0582	viral genome integration into host DNA
AMS64_RS12105	COG0616	signal peptide processing
AMS64_RS12120	COG1802	Transcriptional regulator
AMS64_RS12120	COG4626	Terminase
AMS64_RS12150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMS64_RS12155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMS64_RS12255	COG3646	Phage regulatory protein
AMS64_RS12340	COG0322	excinuclease ABC activity
AMS64_RS12345	COG2197	response regulator
AMS64_RS12350	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMS64_RS12355	COG2835	tetraacyldisaccharide 4'-kinase activity
AMS64_RS12360	COG1663	tetraacyldisaccharide 4'-kinase activity
AMS64_RS12370	COG2333	competence protein COMEC
AMS64_RS12370	COG0658	competence protein
AMS64_RS12385	COG1448	Aminotransferase
AMS64_RS12395	COG0583	DNA-binding transcription factor activity
AMS64_RS12400	COG3085	chromosome segregation
AMS64_RS12405	COG4574	serine-type endopeptidase inhibitor activity
AMS64_RS12410	COG0584	glycerophosphoryl diester phosphodiesterase
AMS64_RS12420	COG1349	DNA-binding transcription factor activity
AMS64_RS12425	COG2271	Major facilitator Superfamily
AMS64_RS12430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMS64_RS12435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMS64_RS12440	COG0840	transmembrane signaling receptor activity
AMS64_RS12450	COG0583	DNA-binding transcription factor activity
AMS64_RS12475	COG0656	L-ascorbic acid biosynthetic process
AMS64_RS12485	COG2814	Major facilitator Superfamily
AMS64_RS12490	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMS64_RS12505	COG3220	belongs to the UPF0276 family
AMS64_RS12525	COG1294	oxidase, subunit
AMS64_RS12535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMS64_RS12545	COG2979	Protein of unknown function (DUF533)
AMS64_RS12550	COG1607	acyl-coa hydrolase
AMS64_RS12555	COG0583	DNA-binding transcription factor activity
AMS64_RS12560	COG2807	transmembrane transport
AMS64_RS12565	COG1187	pseudouridine synthase activity
AMS64_RS12575	COG0346	lactoylglutathione lyase activity
AMS64_RS12600	COG4657	Part of a membrane complex involved in electron transport
AMS64_RS12605	COG2878	Part of a membrane complex involved in electron transport
AMS64_RS12615	COG4658	electron transport chain
AMS64_RS12620	COG4659	FMN binding
AMS64_RS12625	COG4660	Part of a membrane complex involved in electron transport
AMS64_RS12630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMS64_RS12635	COG0346	lactoylglutathione lyase activity
AMS64_RS12670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMS64_RS12675	COG0505	Belongs to the CarA family
AMS64_RS12680	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMS64_RS12695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMS64_RS12700	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AMS64_RS12705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMS64_RS12710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AMS64_RS12715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMS64_RS12720	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AMS64_RS12750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMS64_RS12755	COG0861	Integral membrane protein TerC family
AMS64_RS12770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMS64_RS12775	COG0601	transmembrane transport
AMS64_RS12785	COG2095	MarC family integral membrane protein
AMS64_RS12790	COG1454	alcohol dehydrogenase
AMS64_RS12790	COG1012	belongs to the aldehyde dehydrogenase family
AMS64_RS12795	COG0217	transcriptional regulatory protein
AMS64_RS12800	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMS64_RS12805	COG1801	Protein of unknown function DUF72
AMS64_RS12810	COG4106	trans-aconitate 2-methyltransferase activity
AMS64_RS12815	COG0500	methyltransferase
AMS64_RS12835	COG0450	alkyl hydroperoxide reductase
AMS64_RS12840	COG0583	DNA-binding transcription factor activity
AMS64_RS12845	COG0791	NLP P60 protein
AMS64_RS12850	COG0583	DNA-binding transcription factor activity
AMS64_RS12860	COG3048	D-serine ammonia-lyase activity
AMS64_RS12865	COG0538	isocitrate dehydrogenase activity
AMS64_RS12870	COG2207	Transcriptional regulator
AMS64_RS12875	COG1482	cell wall glycoprotein biosynthetic process
AMS64_RS12880	COG0840	transmembrane signaling receptor activity
AMS64_RS12885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_RS12900	COG3152	Membrane
AMS64_RS12935	COG1309	transcriptional regulator
AMS64_RS12965	COG0534	Mate efflux family protein
AMS64_RS12975	COG2841	Protein conserved in bacteria
AMS64_RS12985	COG5001	Diguanylate cyclase
AMS64_RS12985	COG3300	MHYT domain
AMS64_RS12990	COG3132	Protein of unknown function, DUF480
AMS64_RS13020	COG0708	Exodeoxyribonuclease III
AMS64_RS13055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_RS13060	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_RS13070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMS64_RS13075	COG1120	ATPase activity
AMS64_RS13080	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMS64_RS13085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMS64_RS13090	COG2375	cellular response to nickel ion
AMS64_RS13095	COG3437	response regulator, receiver
AMS64_RS13095	COG0784	Response regulator, receiver
AMS64_RS13105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMS64_RS13110	COG0328	RNA-DNA hybrid ribonuclease activity
AMS64_RS13115	COG2226	methyltransferase
AMS64_RS13120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMS64_RS13125	COG1388	LysM domain
AMS64_RS13125	COG0741	lytic transglycosylase activity
AMS64_RS13150	COG5000	phosphorelay sensor kinase activity
AMS64_RS13150	COG5002	protein histidine kinase activity
AMS64_RS13155	COG0745	RESPONSE REGULATOR receiver
AMS64_RS13160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_RS13165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_RS13180	COG1376	ErfK ybiS ycfS ynhG family protein
AMS64_RS13180	COG1388	LysM domain
AMS64_RS13190	COG0471	metal ion transport
AMS64_RS13200	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AMS64_RS13205	COG0791	NLP P60 protein
AMS64_RS13215	COG3118	belongs to the thioredoxin family
AMS64_RS13225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMS64_RS13230	COG0788	formyltetrahydrofolate deformylase activity
AMS64_RS13240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMS64_RS13260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMS64_RS13270	COG0436	Aminotransferase
AMS64_RS13275	COG1288	antiporter activity
AMS64_RS13280	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMS64_RS13295	COG2964	Protein conserved in bacteria
AMS64_RS13300	COG3681	Belongs to the UPF0597 family
AMS64_RS13310	COG0814	amino acid
AMS64_RS13330	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AMS64_RS13340	COG1166	arginine decarboxylase activity
AMS64_RS13345	COG2195	Cleaves the N-terminal amino acid of tripeptides
AMS64_RS13370	COG2353	YceI-like domain
AMS64_RS13375	COG0583	DNA-binding transcription factor activity
AMS64_RS13385	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AMS64_RS13390	COG0840	transmembrane signaling receptor activity
AMS64_RS13395	COG0840	transmembrane signaling receptor activity
AMS64_RS13400	COG0302	gtp cyclohydrolase
AMS64_RS13410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMS64_RS13445	COG2267	carboxylic ester hydrolase activity
AMS64_RS13450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AMS64_RS13465	COG0314	molybdopterin synthase activity
AMS64_RS13470	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AMS64_RS13475	COG0315	cyclic pyranopterin monophosphate synthase activity
AMS64_RS13480	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMS64_RS13485	COG3005	denitrification pathway
AMS64_RS13495	COG0348	domain, Protein
AMS64_RS13500	COG0437	4 iron, 4 sulfur cluster binding
AMS64_RS13505	COG0243	molybdopterin cofactor binding
AMS64_RS13515	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMS64_RS13520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMS64_RS13525	COG3850	Histidine kinase
AMS64_RS13530	COG2197	response regulator
AMS64_RS13560	COG0121	glutamine amidotransferase
AMS64_RS13565	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMS64_RS13570	COG1960	acyl-CoA dehydrogenase activity
AMS64_RS13575	COG1473	amidohydrolase
AMS64_RS13580	COG2914	Belongs to the UPF0125 (RnfH) family
AMS64_RS13585	COG2867	negative regulation of translational initiation
AMS64_RS13590	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMS64_RS13600	COG0582	viral genome integration into host DNA
AMS64_RS13665	COG0784	Response regulator, receiver
AMS64_RS13665	COG2205	protein histidine kinase activity
AMS64_RS13675	COG3383	formate dehydrogenase (NAD+) activity
AMS64_RS13685	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AMS64_RS13695	COG1960	acyl-CoA dehydrogenase activity
AMS64_RS13700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_RS13710	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AMS64_RS13715	COG1317	bacterial-type flagellum organization
AMS64_RS13720	COG1317	bacterial-type flagellum organization
AMS64_RS13810	COG0457	Tetratricopeptide repeat
AMS64_RS13835	COG0457	Tetratricopeptide repeat
AMS64_RS13880	COG4790	Type iii secretion
AMS64_RS13885	COG4794	Type iii secretion
AMS64_RS13890	COG4791	protein targeting
AMS64_RS13925	COG1120	ATPase activity
AMS64_RS13930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMS64_RS13935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMS64_RS13940	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AMS64_RS13945	COG4772	TonB-dependent receptor
AMS64_RS13975	COG0019	diaminopimelate decarboxylase activity
AMS64_RS13980	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AMS64_RS14000	COG4983	Phage plasmid primase, P4 family domain protein
AMS64_RS14035	COG2003	Belongs to the UPF0758 family
AMS64_RS14115	COG0659	secondary active sulfate transmembrane transporter activity
AMS64_RS14165	COG0582	viral genome integration into host DNA
AMS64_RS14175	COG2314	TM2 domain
AMS64_RS14240	COG1435	thymidine kinase activity
AMS64_RS14245	COG1757	Na H antiporter
AMS64_RS14250	COG2916	Histone family protein nucleoid-structuring protein H-NS
AMS64_RS14255	COG2096	Adenosyltransferase
AMS64_RS14260	COG3530	Putative quorum-sensing-regulated virulence factor
AMS64_RS14265	COG0602	queuosine metabolic process
AMS64_RS14270	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AMS64_RS14290	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AMS64_RS14300	COG0776	regulation of translation
AMS64_RS14305	COG0539	negative regulation of cytoplasmic translation
AMS64_RS14310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMS64_RS14315	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMS64_RS14330	COG2814	Major facilitator Superfamily
AMS64_RS14350	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AMS64_RS14355	COG5001	Diguanylate cyclase
AMS64_RS14355	COG3300	MHYT domain
AMS64_RS14360	COG0583	DNA-binding transcription factor activity
AMS64_RS14365	COG3437	response regulator, receiver
AMS64_RS14390	COG4989	oxidoreductase activity
AMS64_RS14395	COG0724	RNA recognition motif
AMS64_RS14405	COG1126	abc transporter atp-binding protein
AMS64_RS14410	COG0765	amino acid transport
AMS64_RS14415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_RS14420	COG0765	amino acid transport
AMS64_RS14425	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AMS64_RS14435	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AMS64_RS14460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMS64_RS14470	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMS64_RS14475	COG1360	Flagellar Motor Protein
AMS64_RS14480	COG4771	TonB-dependent receptor
AMS64_RS14485	COG1770	oligopeptidase
AMS64_RS14505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_RS14510	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_RS14515	COG0649	NAD binding
AMS64_RS14515	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_RS14530	COG1034	ATP synthesis coupled electron transport
AMS64_RS14535	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMS64_RS14540	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_RS14545	COG0839	Belongs to the complex I subunit 6 family
AMS64_RS14550	COG0713	ATP synthesis coupled electron transport
AMS64_RS14560	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_RS14565	COG1007	ATP synthesis coupled electron transport
AMS64_RS14580	COG2199	diguanylate cyclase activity
AMS64_RS14580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMS64_RS14585	COG3300	MHYT domain
AMS64_RS14585	COG5001	Diguanylate cyclase
AMS64_RS14610	COG2050	protein possibly involved in aromatic compounds catabolism
AMS64_RS14620	COG0247	lactate metabolic process
AMS64_RS14620	COG0277	FAD linked oxidase domain protein
AMS64_RS14630	COG1253	flavin adenine dinucleotide binding
AMS64_RS14635	COG1902	pentaerythritol trinitrate reductase activity
AMS64_RS14650	COG0647	UMP catabolic process
AMS64_RS14655	COG4651	solute:proton antiporter activity
AMS64_RS14655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMS64_RS14665	COG0367	asparagine synthase
AMS64_RS14675	COG0625	glutathione transferase activity
AMS64_RS14685	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AMS64_RS14700	COG0564	pseudouridine synthase activity
AMS64_RS14705	COG4160	amino acid transport
AMS64_RS14715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_RS14725	COG2431	L-lysine efflux transmembrane transporter activity
AMS64_RS14730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AMS64_RS14735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_RS14745	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AMS64_RS14755	COG1393	Belongs to the ArsC family
AMS64_RS14760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMS64_RS14765	COG4783	chaperone-mediated protein folding
AMS64_RS14770	COG0425	Belongs to the sulfur carrier protein TusA family
AMS64_RS14795	COG3842	ATPase activity
AMS64_RS14800	COG3833	ABC-type maltose transport systems, permease component
AMS64_RS14805	COG1175	transmembrane transport
AMS64_RS14815	COG3081	Nucleoid-associated protein
AMS64_RS14820	COG3082	Protein of unknown function (DUF1414)
AMS64_RS14825	COG3083	sulfuric ester hydrolase activity
AMS64_RS14830	COG1464	Belongs to the NlpA lipoprotein family
AMS64_RS14845	COG0574	Belongs to the PEP-utilizing enzyme family
AMS64_RS14845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMS64_RS14850	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AMS64_RS14880	COG0840	transmembrane signaling receptor activity
AMS64_RS14945	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AMS64_RS14955	COG0714	Associated with various cellular activities
AMS64_RS14960	COG3012	SEC-C Motif Domain Protein
AMS64_RS14960	COG3318	Belongs to the UPF0149 family
AMS64_RS14975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMS64_RS14975	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMS64_RS14980	COG0509	glycine decarboxylation via glycine cleavage system
AMS64_RS14985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMS64_RS14990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMS64_RS14995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMS64_RS15015	COG2814	Major facilitator Superfamily
AMS64_RS15020	COG0625	glutathione transferase activity
AMS64_RS15030	COG0483	inositol monophosphate 1-phosphatase activity
AMS64_RS15040	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMS64_RS15055	COG1086	Polysaccharide biosynthesis protein
AMS64_RS15060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMS64_RS15070	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMS64_RS15075	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMS64_RS15140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMS64_RS15140	COG0301	tRNA thio-modification
AMS64_RS15150	COG4953	penicillin-binding protein 1C
AMS64_RS15155	COG2373	Large extracellular alpha-helical protein
AMS64_RS15165	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMS64_RS15175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMS64_RS15185	COG1252	NADH dehydrogenase
AMS64_RS15190	COG3150	esterase
AMS64_RS15195	COG2233	PERMEase
AMS64_RS15205	COG2354	Protein conserved in bacteria
AMS64_RS15220	COG1301	dicarboxylic acid transport
AMS64_RS15235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMS64_RS15250	COG0537	adenosine 5'-monophosphoramidase activity
AMS64_RS15285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMS64_RS15290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMS64_RS15300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMS64_RS15305	COG1605	Chorismate mutase
AMS64_RS15305	COG0287	Prephenate dehydrogenase
AMS64_RS15315	COG1199	ATP-dependent helicase activity
AMS64_RS15325	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMS64_RS15330	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AMS64_RS15335	COG1785	Belongs to the alkaline phosphatase family
AMS64_RS15355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMS64_RS15360	COG2197	response regulator
AMS64_RS15370	COG2271	Major facilitator Superfamily
AMS64_RS15375	COG2199	diguanylate cyclase activity
AMS64_RS15375	COG2203	Gaf domain
AMS64_RS15380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_RS15385	COG0765	amino acid transport
AMS64_RS15390	COG1126	abc transporter atp-binding protein
AMS64_RS15405	COG0531	amino acid
AMS64_RS15420	COG1253	flavin adenine dinucleotide binding
AMS64_RS15425	COG0704	Plays a role in the regulation of phosphate uptake
AMS64_RS15430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMS64_RS15435	COG0581	inorganic phosphate transmembrane transporter activity
AMS64_RS15440	COG0573	inorganic phosphate transmembrane transporter activity
AMS64_RS15445	COG0590	tRNA wobble adenosine to inosine editing
AMS64_RS15455	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMS64_RS15475	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMS64_RS15480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMS64_RS15485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AMS64_RS15615	COG4695	Portal protein
AMS64_RS15715	COG4974	Belongs to the 'phage' integrase family
AMS64_RS15720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AMS64_RS15745	COG2716	regulation of RNA biosynthetic process
AMS64_RS15750	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AMS64_RS15760	COG2239	Acts as a magnesium transporter
AMS64_RS15765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMS64_RS15775	COG3951	Flagellar rod assembly protein muramidase FlgJ
AMS64_RS15775	COG1705	Flagellar rod assembly protein muramidase FlgJ
AMS64_RS15780	COG1706	bacterial-type flagellum-dependent cell motility
AMS64_RS15785	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AMS64_RS15795	COG4787	bacterial-type flagellum-dependent cell motility
AMS64_RS15805	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AMS64_RS15815	COG1815	bacterial-type flagellum-dependent cell motility
AMS64_RS15820	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMS64_RS15825	COG0784	Response regulator, receiver
AMS64_RS15825	COG0835	chemotaxis
AMS64_RS15830	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AMS64_RS15845	COG0622	Phosphoesterase
AMS64_RS15850	COG4166	transmembrane transport
AMS64_RS15865	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMS64_RS15875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMS64_RS15880	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMS64_RS15885	COG1882	Formate acetyltransferase
AMS64_RS15890	COG1349	DNA-binding transcription factor activity
AMS64_RS15895	COG4166	transmembrane transport
AMS64_RS15920	COG1278	Cold shock
AMS64_RS15945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMS64_RS15945	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AMS64_RS15950	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_RS15955	COG1535	isochorismatase
AMS64_RS15955	COG3433	isochorismatase activity
AMS64_RS15960	COG1021	2,3-dihydroxybenzoate-AMP ligase
AMS64_RS15965	COG1169	isochorismate synthase
AMS64_RS15970	COG4771	TonB-dependent receptor
AMS64_RS15975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMS64_RS15980	COG1609	Transcriptional regulator
AMS64_RS15985	COG0741	lytic transglycosylase activity
AMS64_RS15995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AMS64_RS16015	COG2911	Protein conserved in bacteria
AMS64_RS16020	COG0729	surface antigen
AMS64_RS16030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMS64_RS16040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMS64_RS16050	COG4134	Bacterial extracellular solute-binding protein
AMS64_RS16060	COG4136	ATPase activity
AMS64_RS16065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMS64_RS16070	COG2951	lytic endotransglycosylase activity
AMS64_RS16075	COG0033	Phosphoglucomutase
AMS64_RS16080	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AMS64_RS16085	COG0596	Alpha beta hydrolase
AMS64_RS16100	COG0716	FMN binding
AMS64_RS16110	COG0735	belongs to the Fur family
AMS64_RS16115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMS64_RS16125	COG2190	(PTS) system
AMS64_RS16125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_RS16125	COG1263	PTS System
AMS64_RS16130	COG0363	glucosamine-6-phosphate deaminase activity
AMS64_RS16135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AMS64_RS16140	COG1940	carbohydrate kinase activity
AMS64_RS16140	COG1846	Transcriptional regulator
AMS64_RS16150	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMS64_RS16150	COG2199	diguanylate cyclase activity
AMS64_RS16155	COG3275	phosphorelay sensor kinase activity
AMS64_RS16160	COG3279	Response regulator of the LytR AlgR family
AMS64_RS16165	COG1966	Carbon starvation protein
AMS64_RS16175	COG1566	PFAM secretion protein HlyD family protein
AMS64_RS16180	COG1061	Type III restriction enzyme res subunit
AMS64_RS16185	COG2027	D-alanyl-D-alanine carboxypeptidase
AMS64_RS16190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMS64_RS16195	COG3021	interspecies interaction between organisms
AMS64_RS16205	COG1607	acyl-coa hydrolase
AMS64_RS16210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMS64_RS16220	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMS64_RS16220	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMS64_RS16220	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AMS64_RS16220	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMS64_RS16235	COG0633	Ferredoxin
AMS64_RS16235	COG0633	Ferredoxin
AMS64_RS16235	COG3217	Mosc domain protein beta barrel domain protein
AMS64_RS16235	COG3217	Mosc domain protein beta barrel domain protein
AMS64_RS16245	COG0501	Belongs to the peptidase M48B family
AMS64_RS16250	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AMS64_RS16255	COG1073	alpha beta
AMS64_RS16255	COG2226	methyltransferase
AMS64_RS16260	COG0156	8-amino-7-oxononanoate synthase activity
AMS64_RS16265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMS64_RS16270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMS64_RS16285	COG0017	Asparaginyl-tRNA synthetase
AMS64_RS16295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AMS64_RS16310	COG1393	Belongs to the ArsC family
AMS64_RS16315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMS64_RS16320	COG1876	peptidase activity
AMS64_RS16325	COG3263	regulation of cellular component size
AMS64_RS16340	COG1280	lysine exporter protein (LysE YggA)
AMS64_RS16370	COG1957	nucleoside hydrolase
AMS64_RS16375	COG0564	pseudouridine synthase activity
AMS64_RS16385	COG1454	alcohol dehydrogenase
AMS64_RS16390	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMS64_RS16395	COG0702	epimerase
AMS64_RS16405	COG0095	Lipoate-protein ligase
AMS64_RS16415	COG1136	(ABC) transporter
AMS64_RS16415	COG0577	efflux transmembrane transporter activity
AMS64_RS16420	COG0577	efflux transmembrane transporter activity
AMS64_RS16420	COG1136	(ABC) transporter
AMS64_RS16425	COG1136	(ABC) transporter
AMS64_RS16425	COG0577	efflux transmembrane transporter activity
AMS64_RS16430	COG1566	PFAM secretion protein HlyD family protein
AMS64_RS16465	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMS64_RS16475	COG1285	pathogenesis
AMS64_RS16505	COG0484	heat shock protein binding
AMS64_RS16510	COG0443	Heat shock 70 kDa protein
AMS64_RS16515	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMS64_RS16520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMS64_RS16525	COG0497	DNA recombination
AMS64_RS16530	COG1227	inorganic diphosphatase activity
AMS64_RS16535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_RS16540	COG1136	(ABC) transporter
AMS64_RS16540	COG0577	efflux transmembrane transporter activity
AMS64_RS16565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMS64_RS16575	COG0297	glycogen (starch) synthase activity
AMS64_RS16580	COG0463	Glycosyl transferase, family 2
AMS64_RS16580	COG1216	Glycosyl transferase, family 2
AMS64_RS16595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMS64_RS16610	COG2755	lipolytic protein G-D-S-L family
AMS64_RS16610	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMS64_RS16690	COG1459	type II secretion system
AMS64_RS16710	COG1091	dTDP-4-dehydrorhamnose reductase activity
AMS64_RS16720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_RS16725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_RS16730	COG1309	transcriptional regulator
AMS64_RS16745	COG1342	Belongs to the UPF0251 family
AMS64_RS16765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMS64_RS16815	COG0813	purine-nucleoside phosphorylase activity
AMS64_RS16825	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AMS64_RS16830	COG0083	homoserine kinase activity
AMS64_RS16840	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AMS64_RS16845	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AMS64_RS16850	COG1946	Acyl-CoA thioesterase
AMS64_RS16865	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMS64_RS16875	COG0009	L-threonylcarbamoyladenylate synthase
AMS64_RS16885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMS64_RS16890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMS64_RS16890	COG0512	Glutamine amidotransferase of anthranilate synthase
AMS64_RS16895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMS64_RS16900	COG0135	phosphoribosylanthranilate isomerase activity
AMS64_RS16900	COG0134	indole-3-glycerol-phosphate synthase activity
AMS64_RS16905	COG0133	tryptophan synthase activity
AMS64_RS16910	COG0159	tryptophan synthase activity
AMS64_RS16920	COG1988	membrane-bound metal-dependent
AMS64_RS16935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMS64_RS16945	COG0798	PFAM Bile acid sodium symporter
AMS64_RS16975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMS64_RS16985	COG0745	RESPONSE REGULATOR receiver
AMS64_RS17000	COG4988	ABC transporter
AMS64_RS17005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AMS64_RS17025	COG1720	tRNA m6t6A37 methyltransferase activity
AMS64_RS17030	COG3038	cytochrome b561
AMS64_RS17050	COG2862	Uncharacterized protein family, UPF0114
AMS64_RS17065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_RS17070	COG1396	sequence-specific DNA binding
AMS64_RS17070	COG1917	Cupin 2, conserved barrel domain protein
AMS64_RS17085	COG0531	amino acid
AMS64_RS17100	COG0531	amino acid
AMS64_RS17105	COG1283	sodium-dependent phosphate transmembrane transporter activity
AMS64_RS17120	COG2974	May be involved in recombination
AMS64_RS17130	COG0420	3'-5' exonuclease activity
AMS64_RS17135	COG0419	ATPase involved in DNA repair
AMS64_RS17140	COG3384	dioxygenase
AMS64_RS17150	COG0469	pyruvate kinase activity
AMS64_RS17155	COG3264	Mechanosensitive ion channel
AMS64_RS17155	COG1196	nuclear chromosome segregation
AMS64_RS17165	COG3590	peptidase
AMS64_RS17170	COG3706	GGDEF domain
AMS64_RS17175	COG2190	(PTS) system
AMS64_RS17185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_RS17190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMS64_RS17195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMS64_RS17210	COG3437	response regulator, receiver
AMS64_RS17210	COG2770	Histidine kinase
AMS64_RS17215	COG3409	Peptidoglycan-binding domain 1 protein
AMS64_RS17215	COG3267	Type II secretory pathway component ExeA
AMS64_RS17235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMS64_RS17240	COG1459	type II secretion system
AMS64_RS17245	COG2165	general secretion pathway protein
AMS64_RS17255	COG2165	general secretion pathway protein
AMS64_RS17260	COG4795	General secretion pathway protein
AMS64_RS17265	COG3156	type II secretion system protein K
AMS64_RS17275	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AMS64_RS17290	COG0670	Belongs to the BI1 family
AMS64_RS17295	COG1289	transmembrane transporter activity
AMS64_RS17300	COG2920	part of a sulfur-relay system
AMS64_RS17305	COG0673	inositol 2-dehydrogenase activity
AMS64_RS17310	COG0583	DNA-binding transcription factor activity
AMS64_RS17350	COG1032	radical SAM domain protein
AMS64_RS17360	COG1566	PFAM secretion protein HlyD family protein
AMS64_RS17365	COG3706	GGDEF domain
AMS64_RS17370	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMS64_RS17405	COG0531	amino acid
AMS64_RS17435	COG0281	malic enzyme
AMS64_RS17445	COG0534	Mate efflux family protein
AMS64_RS17460	COG2233	PERMEase
AMS64_RS17465	COG0095	Lipoate-protein ligase
AMS64_RS17470	COG1115	amino acid carrier protein
AMS64_RS17475	COG0019	diaminopimelate decarboxylase activity
AMS64_RS17485	COG0678	peroxiredoxin activity
AMS64_RS17510	COG0545	Peptidyl-prolyl cis-trans isomerase
AMS64_RS17515	COG3142	Participates in the control of copper homeostasis
AMS64_RS17540	COG5002	protein histidine kinase activity
AMS64_RS17545	COG0745	RESPONSE REGULATOR receiver
AMS64_RS17550	COG0346	lactoylglutathione lyase activity
AMS64_RS17555	COG3284	Transcriptional regulator
AMS64_RS17570	COG0697	spore germination
AMS64_RS17580	COG3290	protein histidine kinase activity
AMS64_RS17585	COG0281	malic enzyme
AMS64_RS17595	COG1846	Transcriptional regulator
AMS64_RS17600	COG1566	PFAM secretion protein HlyD family protein
AMS64_RS17625	COG0602	queuosine metabolic process
AMS64_RS17630	COG1328	CTP reductase activity
AMS64_RS17640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMS64_RS17645	COG3115	cell septum assembly
AMS64_RS17650	COG1196	nuclear chromosome segregation
AMS64_RS17660	COG2860	membrane
AMS64_RS17670	COG3108	Peptidase M15
AMS64_RS17675	COG2989	Protein conserved in bacteria
AMS64_RS17690	COG0463	Glycosyl transferase, family 2
AMS64_RS17705	COG0366	Alpha amylase catalytic
AMS64_RS17740	COG2199	diguanylate cyclase activity
AMS64_RS17740	COG2203	Gaf domain
AMS64_RS17750	COG3590	peptidase
AMS64_RS17765	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AMS64_RS17770	COG1982	Orn Lys Arg decarboxylase major
AMS64_RS17775	COG0531	amino acid
AMS64_RS17780	COG3710	Transcriptional regulator
AMS64_RS17785	COG0531	amino acid
AMS64_RS17805	COG0814	amino acid
AMS64_RS17835	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMS64_RS17840	COG0739	heme binding
AMS64_RS17845	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AMS64_RS17855	COG0251	oxidation-reduction process
AMS64_RS17870	COG0583	DNA-binding transcription factor activity
AMS64_RS17875	COG3321	synthase
AMS64_RS17875	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_RS17875	COG0604	alcohol dehydrogenase
AMS64_RS17885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AMS64_RS17895	COG3091	SprT-like family
AMS64_RS17905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMS64_RS17910	COG0189	ligase activity
AMS64_RS17915	COG1678	Uncharacterized ACR, COG1678
AMS64_RS17920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMS64_RS17925	COG3104	oligopeptide transport
AMS64_RS17940	COG0714	Associated with various cellular activities
AMS64_RS17955	COG1115	amino acid carrier protein
AMS64_RS17960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMS64_RS17970	COG0825	malonyl-CoA metabolic process
AMS64_RS17980	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AMS64_RS17985	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMS64_RS17990	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMS64_RS17995	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMS64_RS18000	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMS64_RS18015	COG0750	zinc metalloprotease
AMS64_RS18020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AMS64_RS18025	COG0575	Belongs to the CDS family
AMS64_RS18030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMS64_RS18035	COG0233	cytoplasmic translational termination
AMS64_RS18040	COG0528	UMP kinase activity
AMS64_RS18045	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMS64_RS18050	COG0052	Belongs to the universal ribosomal protein uS2 family
AMS64_RS18055	COG0024	Methionine aminopeptidase
AMS64_RS18060	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMS64_RS18065	COG2171	N-acyltransferase activity
AMS64_RS18075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_RS18075	COG1263	PTS System
AMS64_RS18085	COG4580	involved in the transport of maltose and maltodextrins
AMS64_RS18095	COG0564	pseudouridine synthase activity
AMS64_RS18100	COG3098	single-species biofilm formation
AMS64_RS18125	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AMS64_RS18135	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMS64_RS18135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMS64_RS18150	COG1611	Belongs to the LOG family
AMS64_RS18155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMS64_RS18160	COG0473	3-isopropylmalate dehydrogenase activity
AMS64_RS18170	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AMS64_RS18175	COG2363	Small membrane protein
AMS64_RS18185	COG0583	DNA-binding transcription factor activity
AMS64_RS18190	COG0840	transmembrane signaling receptor activity
AMS64_RS18195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMS64_RS18210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMS64_RS18215	COG1666	GTP binding
AMS64_RS18220	COG3248	Nucleoside-binding outer membrane protein
AMS64_RS18225	COG2211	Major facilitator Superfamily
AMS64_RS18230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMS64_RS18240	COG2813	Specifically methylates the guanine in position
AMS64_RS18245	COG0271	Belongs to the BolA IbaG family
AMS64_RS18250	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMS64_RS18255	COG1805	sodium ion transport
AMS64_RS18260	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMS64_RS18265	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMS64_RS18270	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMS64_RS18275	COG2871	sodium ion transport
AMS64_RS18280	COG1477	protein flavinylation
AMS64_RS18310	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMS64_RS18325	COG0300	oxidoreductase activity
AMS64_RS18335	COG0415	Belongs to the DNA photolyase family
AMS64_RS18340	COG0789	Transcriptional regulator
AMS64_RS18345	COG3272	Protein of unknown function (DUF1722)
AMS64_RS18375	COG1605	Chorismate mutase
AMS64_RS18375	COG0077	Prephenate dehydratase
AMS64_RS18405	COG5377	YqaJ viral recombinase family
AMS64_RS18450	COG2003	Belongs to the UPF0758 family
AMS64_RS18540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMS64_RS18595	COG3501	Rhs element vgr protein
AMS64_RS18620	COG0300	oxidoreductase activity
AMS64_RS18645	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AMS64_RS18685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMS64_RS18690	COG0826	peptidase U32
AMS64_RS18695	COG1280	lysine exporter protein (LysE YggA)
AMS64_RS18705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMS64_RS18715	COG0745	RESPONSE REGULATOR receiver
AMS64_RS18725	COG0643	Histidine kinase
AMS64_RS18725	COG2198	Histidine kinase
AMS64_RS18735	COG0835	chemotaxis
AMS64_RS18740	COG0840	transmembrane signaling receptor activity
AMS64_RS18750	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AMS64_RS18755	COG2201	protein-glutamate methylesterase activity
AMS64_RS18760	COG1185	polyribonucleotide nucleotidyltransferase activity
AMS64_RS18765	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMS64_RS18770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMS64_RS18775	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AMS64_RS18780	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AMS64_RS18785	COG0195	Participates in both transcription termination and antitermination
AMS64_RS18790	COG0779	Required for maturation of 30S ribosomal subunits
AMS64_RS18805	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMS64_RS18810	COG0149	triose-phosphate isomerase activity
AMS64_RS18815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMS64_RS18820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMS64_RS18830	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AMS64_RS18835	COG1534	Rna-binding protein
AMS64_RS18850	COG1360	Flagellar Motor Protein
AMS64_RS18855	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMS64_RS18860	COG1722	exodeoxyribonuclease VII activity
AMS64_RS18865	COG0142	geranyltranstransferase activity
AMS64_RS18870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMS64_RS18880	COG0601	transmembrane transport
AMS64_RS18895	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AMS64_RS18900	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AMS64_RS18905	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMS64_RS18910	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMS64_RS18930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMS64_RS18930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMS64_RS18935	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMS64_RS18940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMS64_RS18950	COG0784	Response regulator, receiver
AMS64_RS18950	COG2198	Histidine kinase
AMS64_RS18950	COG2205	protein histidine kinase activity
AMS64_RS18955	COG1879	ABC-type sugar transport system periplasmic component
AMS64_RS18965	COG0745	RESPONSE REGULATOR receiver
AMS64_RS18970	COG3005	denitrification pathway
AMS64_RS18980	COG3381	protein complex oligomerization
AMS64_RS19000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMS64_RS19005	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMS64_RS19010	COG0511	ligase activity, forming carbon-carbon bonds
AMS64_RS19015	COG0439	Biotin carboxylase
AMS64_RS19025	COG4145	pantothenate transmembrane transporter activity
AMS64_RS19030	COG1263	PTS System
AMS64_RS19030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_RS19030	COG2190	(PTS) system
AMS64_RS19035	COG0583	DNA-binding transcription factor activity
AMS64_RS19040	COG0604	alcohol dehydrogenase
AMS64_RS19045	COG2264	protein methyltransferase activity
AMS64_RS19055	COG0778	Nitroreductase
AMS64_RS19060	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMS64_RS19060	COG1902	pentaerythritol trinitrate reductase activity
AMS64_RS19065	COG0616	signal peptide processing
AMS64_RS19085	COG0848	biopolymer transport protein
AMS64_RS19090	COG0811	peptide transport
AMS64_RS19095	COG0811	peptide transport
AMS64_RS19110	COG4174	ABC transporter (Permease)
AMS64_RS19115	COG4239	(ABC) transporter, permease
AMS64_RS19125	COG0444	Belongs to the ABC transporter superfamily
AMS64_RS19130	COG4608	Belongs to the ABC transporter superfamily
AMS64_RS19150	COG3416	Protein conserved in bacteria
AMS64_RS19180	COG0488	(ABC) transporter
AMS64_RS19190	COG2252	PERMEase
AMS64_RS19195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMS64_RS19200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMS64_RS19205	COG0840	transmembrane signaling receptor activity
AMS64_RS19215	COG1278	Cold shock
AMS64_RS19255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AMS64_RS19260	COG1162	GTPase activity
AMS64_RS19265	COG0688	phosphatidylethanolamine metabolic process
AMS64_RS19270	COG4628	conserved protein (DUF2132)
AMS64_RS19285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMS64_RS19300	COG1073	alpha beta
AMS64_RS19305	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AMS64_RS19310	COG2195	Cleaves the N-terminal amino acid of tripeptides
AMS64_RS19315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMS64_RS19320	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMS64_RS19325	COG3178	'Phosphotransferase
AMS64_RS19330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AMS64_RS19335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMS64_RS19340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMS64_RS19345	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMS64_RS19350	COG2967	ApaG domain
AMS64_RS19355	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMS64_RS19370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMS64_RS19380	COG3314	Sporulation integral membrane protein YlbJ
AMS64_RS19385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMS64_RS19390	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMS64_RS19400	COG0142	geranyltranstransferase activity
AMS64_RS19405	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AMS64_RS19410	COG0330	HflC and HflK could
AMS64_RS19415	COG0330	HflC and HflK could
AMS64_RS19420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMS64_RS19425	COG1923	regulation of RNA biosynthetic process
AMS64_RS19430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMS64_RS19435	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AMS64_RS19440	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AMS64_RS19450	COG0802	atpase or kinase
AMS64_RS19455	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMS64_RS19455	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AMS64_RS19475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMS64_RS19480	COG2011	ABC-type metal ion transport system permease component
AMS64_RS19485	COG1464	Belongs to the NlpA lipoprotein family
AMS64_RS19505	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMS64_RS19510	COG2198	Histidine kinase
AMS64_RS19510	COG0784	Response regulator, receiver
AMS64_RS19510	COG5002	protein histidine kinase activity
AMS64_RS19545	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMS64_RS19550	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AMS64_RS19555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMS64_RS19560	COG2716	regulation of RNA biosynthetic process
AMS64_RS19565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMS64_RS19570	COG3013	Belongs to the UPF0304 family
AMS64_RS19580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMS64_RS19585	COG0857	belongs to the CobB CobQ family
AMS64_RS19585	COG0280	phosphate acetyltransferase
AMS64_RS19590	COG1555	photosystem II stabilization
AMS64_RS19595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AMS64_RS19600	COG3104	oligopeptide transport
AMS64_RS19605	COG0745	RESPONSE REGULATOR receiver
AMS64_RS19635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_RS19650	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AMS64_RS19670	COG0440	acetolactate synthase activity
AMS64_RS19675	COG0028	Belongs to the TPP enzyme family
AMS64_RS19695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMS64_RS19700	COG0473	3-isopropylmalate dehydrogenase activity
AMS64_RS19705	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMS64_RS19710	COG0066	3-isopropylmalate dehydratase activity
AMS64_RS19725	COG4143	(ABC) transporter
AMS64_RS19730	COG1178	ABC-type Fe3 transport system permease component
AMS64_RS19735	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AMS64_RS19740	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AMS64_RS19790	COG0459	protein refolding
AMS64_RS19795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMS64_RS19800	COG0534	Mate efflux family protein
AMS64_RS19805	COG3030	protein affecting phage T7 exclusion by the F plasmid
AMS64_RS19810	COG1027	Aspartate ammonia-lyase
AMS64_RS19815	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AMS64_RS19820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMS64_RS19825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AMS64_RS19830	COG1610	YqeY-like protein
AMS64_RS19835	COG0358	DNA primase activity
AMS64_RS19840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMS64_RS19860	COG0151	Belongs to the GarS family
AMS64_RS19865	COG0138	bifunctional purine biosynthesis protein purh
AMS64_RS19875	COG3036	rescue of stalled ribosome
AMS64_RS19885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMS64_RS19890	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMS64_RS19900	COG0673	inositol 2-dehydrogenase activity
AMS64_RS19910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMS64_RS19915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMS64_RS19925	COG0583	DNA-binding transcription factor activity
AMS64_RS19930	COG0477	Major facilitator Superfamily
AMS64_RS19945	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_RS19955	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AMS64_RS19960	COG0714	Associated with various cellular activities
AMS64_RS19970	COG0456	acetyltransferase
AMS64_RS19980	COG1022	Amp-dependent synthetase and ligase
AMS64_RS19985	COG2918	glutathione biosynthetic process
AMS64_RS19990	COG0612	Peptidase, M16
AMS64_RS19995	COG1238	metal cluster binding
AMS64_RS20000	COG1064	alcohol dehydrogenase
AMS64_RS20020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMS64_RS20025	COG0359	binds to the 23S rRNA
AMS64_RS20030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMS64_RS20035	COG0360	Binds together with S18 to 16S ribosomal RNA
AMS64_RS20040	COG1914	H( )-stimulated, divalent metal cation uptake system
AMS64_RS20045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMS64_RS20055	COG0776	regulation of translation
AMS64_RS20070	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AMS64_RS20085	COG0560	Phosphoserine phosphatase
AMS64_RS20095	COG0813	purine-nucleoside phosphorylase activity
AMS64_RS20100	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AMS64_RS20105	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AMS64_RS20110	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AMS64_RS20120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMS64_RS20125	COG0084	hydrolase, TatD family'
AMS64_RS20130	COG2165	general secretion pathway protein
AMS64_RS20135	COG1854	S-ribosylhomocysteine lyase activity
AMS64_RS20150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMS64_RS20150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMS64_RS20185	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMS64_RS20190	COG1047	Peptidyl-prolyl cis-trans
AMS64_RS20195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMS64_RS20200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMS64_RS20205	COG0196	riboflavin kinase activity
AMS64_RS20210	COG0728	peptidoglycan biosynthetic process
AMS64_RS20215	COG0268	Binds directly to 16S ribosomal RNA
AMS64_RS20220	COG0640	Transcriptional regulator
AMS64_RS20225	COG0583	DNA-binding transcription factor activity
AMS64_RS20235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMS64_RS20240	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AMS64_RS20245	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMS64_RS20250	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AMS64_RS20255	COG1051	belongs to the nudix hydrolase family
AMS64_RS20260	COG3066	DNA modification
AMS64_RS20270	COG0335	large ribosomal subunit rRNA binding
AMS64_RS20275	COG0336	Belongs to the RNA methyltransferase TrmD family
AMS64_RS20280	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AMS64_RS20285	COG0228	four-way junction DNA binding
AMS64_RS20290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMS64_RS20295	COG4137	Cytochrome C assembly protein
AMS64_RS20300	COG4536	flavin adenine dinucleotide binding
AMS64_RS20310	COG1017	nitric oxide dioxygenase activity
AMS64_RS20310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMS64_RS20315	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AMS64_RS20320	COG0039	L-malate dehydrogenase activity
AMS64_RS20325	COG4160	amino acid transport
AMS64_RS20330	COG4215	(ABC) transporter
AMS64_RS20335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_RS20340	COG1126	abc transporter atp-binding protein
AMS64_RS20345	COG1438	arginine binding
AMS64_RS20350	COG2837	iron assimilation
AMS64_RS20355	COG3842	ATPase activity
AMS64_RS20365	COG1840	ABC-type Fe3 transport system, periplasmic component
AMS64_RS20370	COG0347	Belongs to the P(II) protein family
AMS64_RS20390	COG3022	response to hydroperoxide
AMS64_RS20405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AMS64_RS20410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMS64_RS20415	COG0762	integral membrane protein
AMS64_RS20420	COG1872	DUF167
AMS64_RS20430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMS64_RS20435	COG0583	DNA-binding transcription factor activity
AMS64_RS20450	COG1929	Belongs to the glycerate kinase type-1 family
AMS64_RS20455	COG2610	gluconate transmembrane transporter activity
AMS64_RS20460	COG3835	regulator
AMS64_RS20465	COG3112	Uncharacterised protein family (UPF0231)
AMS64_RS20495	COG0513	Belongs to the DEAD box helicase family
AMS64_RS20535	COG1448	Aminotransferase
AMS64_RS20540	COG0583	DNA-binding transcription factor activity
AMS64_RS20550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMS64_RS20555	COG1328	CTP reductase activity
AMS64_RS20580	COG0633	Ferredoxin
AMS64_RS20580	COG0543	2 iron, 2 sulfur cluster binding
AMS64_RS20595	COG1215	transferase activity, transferring glycosyl groups
AMS64_RS20600	COG0726	polysaccharide deacetylase
AMS64_RS20600	COG1649	PFAM Uncharacterised BCR, COG1649
AMS64_RS20615	COG4783	chaperone-mediated protein folding
AMS64_RS20620	COG1215	transferase activity, transferring glycosyl groups
AMS64_RS20625	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AMS64_RS20635	COG0840	transmembrane signaling receptor activity
AMS64_RS20640	COG3397	chitin binding
AMS64_RS20645	COG0583	DNA-binding transcription factor activity
AMS64_RS20650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AMS64_RS20655	COG4208	sulfate ABC transporter
AMS64_RS20660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AMS64_RS20670	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AMS64_RS20675	COG3174	membrane
AMS64_RS20680	COG0110	maltose O-acetyltransferase activity
AMS64_RS20695	COG1011	Hydrolase
AMS64_RS20700	COG0494	nUDIX hydrolase
AMS64_RS20705	COG1218	3'(2'),5'-bisphosphate nucleotidase
AMS64_RS20710	COG0814	amino acid
AMS64_RS20715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMS64_RS20730	COG0626	cystathionine gamma-synthase activity
AMS64_RS20735	COG0527	aspartate kinase activity
AMS64_RS20735	COG0460	homoserine dehydrogenase
AMS64_RS20740	COG0306	phosphate transporter
AMS64_RS20745	COG1392	Phosphate transport regulator
AMS64_RS20755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMS64_RS20760	COG2813	Specifically methylates the guanine in position
AMS64_RS20765	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AMS64_RS20770	COG0297	glycogen (starch) synthase activity
AMS64_RS20820	COG1757	Na H antiporter
AMS64_RS20825	COG0316	Belongs to the HesB IscA family
AMS64_RS20835	COG0038	chloride channel
AMS64_RS20840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMS64_RS20855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMS64_RS20855	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMS64_RS20890	COG1396	sequence-specific DNA binding
AMS64_RS20895	COG3135	benzoate transporter
AMS64_RS20920	COG0840	transmembrane signaling receptor activity
AMS64_RS20925	COG3047	cAMP biosynthetic process
AMS64_RS20930	COG2199	diguanylate cyclase activity
AMS64_RS20935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMS64_RS20970	COG2197	response regulator
AMS64_RS20995	COG1278	Cold shock
AMS64_RS21000	COG2252	PERMEase
AMS64_RS21005	COG2376	Dihydroxyacetone kinase
AMS64_RS21010	COG1461	Dihydroxyacetone kinase
AMS64_RS21025	COG3284	Transcriptional regulator
AMS64_RS21035	COG0628	permease
AMS64_RS21040	COG0494	nUDIX hydrolase
AMS64_RS21055	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AMS64_RS21060	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AMS64_RS21080	COG0456	acetyltransferase
AMS64_RS21085	COG3133	Outer membrane lipoprotein
AMS64_RS21090	COG0004	ammonium transporteR
AMS64_RS21095	COG3706	GGDEF domain
AMS64_RS21105	COG3932	Exopolysaccharide synthesis, ExoD
AMS64_RS21110	COG0814	amino acid
AMS64_RS21115	COG3706	GGDEF domain
AMS64_RS21125	COG0110	maltose O-acetyltransferase activity
AMS64_RS21150	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMS64_RS21155	COG2022	thiamine diphosphate biosynthetic process
AMS64_RS21165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMS64_RS21170	COG0352	thiamine-phosphate diphosphorylase activity
AMS64_RS21175	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AMS64_RS21200	COG0745	RESPONSE REGULATOR receiver
AMS64_RS21205	COG0642	Histidine kinase
AMS64_RS21210	COG0189	ligase activity
AMS64_RS21225	COG0582	viral genome integration into host DNA
AMS64_RS21250	COG1715	Restriction endonuclease
AMS64_RS21260	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AMS64_RS21315	COG0477	Major facilitator Superfamily
AMS64_RS21330	COG0312	modulator of DNA gyrase
AMS64_RS21335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMS64_RS21345	COG3164	Protein of unknown function
AMS64_RS21350	COG1530	ribonuclease E activity
AMS64_RS21355	COG0424	maF-like protein
AMS64_RS21360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AMS64_RS21365	COG1792	Involved in formation and maintenance of cell shape
AMS64_RS21370	COG1077	Cell shape determining protein MreB Mrl
AMS64_RS21395	COG4968	Prepilin-type N-terminal cleavage methylation domain
AMS64_RS21400	COG4969	Belongs to the N-Me-Phe pilin family
AMS64_RS21415	COG1459	type II secretion system
AMS64_RS21420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMS64_RS21465	COG2199	diguanylate cyclase activity
AMS64_RS21465	COG2200	EAL domain
AMS64_RS21470	COG2200	EAL domain
AMS64_RS21475	COG0387	Pfam Sodium calcium exchanger
AMS64_RS21480	COG2986	histidine ammonia-lyase
AMS64_RS21485	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AMS64_RS21490	COG0010	Belongs to the arginase family
AMS64_RS21495	COG1228	amidohydrolase
AMS64_RS21500	COG2188	Transcriptional regulator
AMS64_RS21505	COG0288	reversible hydration of carbon dioxide
AMS64_RS21515	COG2177	Part of the ABC transporter FtsEX involved in
AMS64_RS21520	COG2884	Cell division ATP-binding protein ftsE
AMS64_RS21525	COG0552	protein localization to endoplasmic reticulum
AMS64_RS21530	COG0742	ribosomal rna small subunit methyltransferase
AMS64_RS21555	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMS64_RS21565	COG4221	oxidoreductase activity
AMS64_RS21580	COG1770	oligopeptidase
AMS64_RS21595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMS64_RS21600	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AMS64_RS21610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMS64_RS21620	COG2095	MarC family integral membrane protein
AMS64_RS21630	COG1301	dicarboxylic acid transport
AMS64_RS21655	COG3714	YhhN family
AMS64_RS21700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMS64_RS21705	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMS64_RS21710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMS64_RS21715	COG0049	tRNA binding
AMS64_RS21720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMS64_RS21725	COG2168	tRNA wobble position uridine thiolation
AMS64_RS21730	COG2923	Belongs to the DsrF TusC family
AMS64_RS21735	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AMS64_RS21745	COG2964	Protein conserved in bacteria
AMS64_RS21750	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMS64_RS21755	COG0085	RNA polymerase activity
AMS64_RS21760	COG0222	ribosome binding
AMS64_RS21765	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMS64_RS21770	COG0081	regulation of translation
AMS64_RS21775	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMS64_RS21780	COG0250	Participates in transcription elongation, termination and antitermination
AMS64_RS21795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMS64_RS21820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMS64_RS21825	COG0569	domain protein
AMS64_RS21830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMS64_RS21860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_RS21860	COG4191	Histidine kinase
AMS64_RS21865	COG3005	denitrification pathway
AMS64_RS21870	COG0243	molybdopterin cofactor binding
AMS64_RS21915	COG2204	response regulator
AMS64_RS21925	COG2205	protein histidine kinase activity
AMS64_RS21935	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_RS21940	COG0516	GMP reductase activity
AMS64_RS21940	COG0517	IMP dehydrogenase activity
AMS64_RS21945	COG5413	integral membrane protein
AMS64_RS21955	COG1522	sequence-specific DNA binding
AMS64_RS21960	COG2502	aspartate--ammonia ligase
AMS64_RS21965	COG0542	response to heat
AMS64_RS21975	COG0564	pseudouridine synthase activity
AMS64_RS21980	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMS64_RS21985	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMS64_RS21995	COG3681	Belongs to the UPF0597 family
AMS64_RS22000	COG2964	Protein conserved in bacteria
AMS64_RS22010	COG4974	Belongs to the 'phage' integrase family
AMS64_RS22025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMS64_RS22185	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AMS64_RS22190	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AMS64_RS22195	COG1979	alcohol dehydrogenase
AMS64_RS22200	COG2207	Transcriptional regulator
AMS64_RS22220	COG0583	DNA-binding transcription factor activity
AMS64_RS22235	COG0540	Belongs to the ATCase OTCase family
AMS64_RS22240	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AMS64_RS22245	COG1438	arginine binding
AMS64_RS22250	COG1288	antiporter activity
AMS64_RS22255	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMS64_RS22280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMS64_RS22290	COG3078	GTPase activator activity
AMS64_RS22305	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AMS64_RS22315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMS64_RS22320	COG0408	coproporphyrinogen oxidase activity
AMS64_RS22325	COG0009	L-threonylcarbamoyladenylate synthase
AMS64_RS22335	COG0551	DNA topoisomerase type I activity
AMS64_RS22340	COG2922	Belongs to the Smg family
AMS64_RS22345	COG0758	DNA mediated transformation
AMS64_RS22350	COG1652	LysM domain
AMS64_RS22355	COG0242	peptide deformylase activity
AMS64_RS22360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMS64_RS22365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMS64_RS22365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMS64_RS22370	COG0569	domain protein
AMS64_RS22375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMS64_RS22380	COG1217	gtp-binding protein TYPA
AMS64_RS22385	COG0174	glutamine synthetase
AMS64_RS22400	COG2204	response regulator
AMS64_RS22405	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMS64_RS22410	COG1322	Protein conserved in bacteria
AMS64_RS22435	COG0583	DNA-binding transcription factor activity
AMS64_RS22440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMS64_RS22440	COG0519	Catalyzes the synthesis of GMP from XMP
AMS64_RS22450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMS64_RS22455	COG1396	sequence-specific DNA binding
AMS64_RS22460	COG1012	belongs to the aldehyde dehydrogenase family
AMS64_RS22465	COG2962	Rard protein
AMS64_RS22475	COG2391	methyltransferase activity
AMS64_RS22490	COG0129	dihydroxy-acid dehydratase activity
AMS64_RS22500	COG3978	acetolactate synthase activity
AMS64_RS22510	COG0606	chelatase, subunit chli
AMS64_RS22520	COG0210	DNA helicase
AMS64_RS22590	COG0606	chelatase, subunit chli
AMS64_RS22595	COG0204	Acyl-transferase
AMS64_RS22600	COG0204	Acyl-transferase
AMS64_RS22605	COG1683	Conserved Protein
AMS64_RS22615	COG1335	isochorismatase
AMS64_RS22625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMS64_RS22630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AMS64_RS22640	COG3084	Protein conserved in bacteria