locus-tag	class	description
CVS41_RS00015	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CVS41_RS00020	COG0848	biopolymer transport protein
CVS41_RS00025	COG0811	peptide transport
CVS41_RS00030	COG0811	peptide transport
CVS41_RS00040	COG2771	luxR family
CVS41_RS00045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CVS41_RS00050	COG1349	DNA-binding transcription factor activity
CVS41_RS00055	COG0745	RESPONSE REGULATOR receiver
CVS41_RS00060	COG2205	protein histidine kinase activity
CVS41_RS00075	COG4452	Inner membrane protein CreD
CVS41_RS00090	COG0297	glycogen (starch) synthase activity
CVS41_RS00090	COG0438	transferase activity, transferring glycosyl groups
CVS41_RS00135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CVS41_RS00140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CVS41_RS00145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CVS41_RS00150	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CVS41_RS00155	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CVS41_RS00160	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CVS41_RS00165	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CVS41_RS00170	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CVS41_RS00180	COG0356	it plays a direct role in the translocation of protons across the membrane
CVS41_RS00190	COG1475	DNA binding
CVS41_RS00195	COG1192	Involved in chromosome partitioning
CVS41_RS00200	COG0357	Ribosomal RNA small subunit methyltransferase G
CVS41_RS00205	COG0445	tRNA wobble uridine modification
CVS41_RS00210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CVS41_RS00220	COG4615	Cyclic peptide transporter
CVS41_RS00225	COG1120	ATPase activity
CVS41_RS00230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CVS41_RS00240	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CVS41_RS00245	COG0706	membrane insertase activity
CVS41_RS00250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CVS41_RS00255	COG0594	ribonuclease P activity
CVS41_RS00260	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CVS41_RS00265	COG1126	abc transporter atp-binding protein
CVS41_RS00280	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CVS41_RS00285	COG0592	DNA-directed DNA polymerase activity
CVS41_RS00295	COG0187	DNA topoisomerase II activity
CVS41_RS00315	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CVS41_RS00320	COG0071	Belongs to the small heat shock protein (HSP20) family
CVS41_RS00325	COG0071	Belongs to the small heat shock protein (HSP20) family
CVS41_RS00330	COG3977	Valine--pyruvate aminotransferase
CVS41_RS00345	COG2814	Major facilitator Superfamily
CVS41_RS00350	COG0745	RESPONSE REGULATOR receiver
CVS41_RS00355	COG2205	protein histidine kinase activity
CVS41_RS00380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CVS41_RS00385	COG4191	Histidine kinase
CVS41_RS00385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_RS00390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_RS00395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_RS00400	COG1309	transcriptional regulator
CVS41_RS00430	COG0561	phosphatase activity
CVS41_RS00435	COG2267	carboxylic ester hydrolase activity
CVS41_RS00440	COG0110	maltose O-acetyltransferase activity
CVS41_RS00445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CVS41_RS00450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CVS41_RS00455	COG1758	RNA polymerase activity
CVS41_RS00460	COG0194	GDP metabolic process
CVS41_RS00470	COG0859	PFAM glycosyl transferase family 9
CVS41_RS00475	COG3642	lipopolysaccharide core region biosynthetic process
CVS41_RS00515	COG0589	response to stress
CVS41_RS00525	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CVS41_RS00530	COG1528	Iron-storage protein
CVS41_RS00535	COG2081	HI0933 family
CVS41_RS00540	COG3275	phosphorelay sensor kinase activity
CVS41_RS00545	COG3279	Response regulator of the LytR AlgR family
CVS41_RS00550	COG2223	nitrite transmembrane transporter activity
CVS41_RS00555	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CVS41_RS00560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CVS41_RS00575	COG0583	DNA-binding transcription factor activity
CVS41_RS00585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CVS41_RS00615	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CVS41_RS00620	COG2166	iron-sulfur cluster assembly
CVS41_RS00625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CVS41_RS00640	COG3245	cytochrome
CVS41_RS00645	COG1063	alcohol dehydrogenase
CVS41_RS00660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CVS41_RS00705	COG1280	lysine exporter protein (LysE YggA)
CVS41_RS00755	COG0210	DNA helicase
CVS41_RS00770	COG0840	transmembrane signaling receptor activity
CVS41_RS00775	COG1744	ABC transporter substrate-binding protein PnrA-like
CVS41_RS00780	COG3845	ABC transporter
CVS41_RS00785	COG4603	Belongs to the binding-protein-dependent transport system permease family
CVS41_RS00790	COG1079	Belongs to the binding-protein-dependent transport system permease family
CVS41_RS00800	COG0737	Belongs to the 5'-nucleotidase family
CVS41_RS00810	COG2239	Acts as a magnesium transporter
CVS41_RS00815	COG1648	precorrin-2 dehydrogenase activity
CVS41_RS00815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CVS41_RS00820	COG2116	formate transmembrane transporter activity
CVS41_RS00830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CVS41_RS00835	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CVS41_RS00840	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CVS41_RS00850	COG0018	arginyl-trna synthetase
CVS41_RS00860	COG1595	DNA-templated transcription, initiation
CVS41_RS00870	COG1968	undecaprenyl-diphosphatase activity
CVS41_RS00875	COG2017	converts alpha-aldose to the beta-anomer
CVS41_RS00880	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CVS41_RS00885	COG1085	galactose-1-phosphate uridylyltransferase
CVS41_RS00890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CVS41_RS00895	COG1609	Transcriptional regulator
CVS41_RS00900	COG3250	beta-galactosidase activity
CVS41_RS00910	COG1129	ABC transporter
CVS41_RS00915	COG4211	Belongs to the binding-protein-dependent transport system permease family
CVS41_RS00925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CVS41_RS00940	COG0366	Alpha amylase catalytic
CVS41_RS00955	COG0443	Heat shock 70 kDa protein
CVS41_RS00960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CVS41_RS00965	COG3045	CreA protein
CVS41_RS00985	COG0174	glutamine synthetase
CVS41_RS01005	COG3842	ATPase activity
CVS41_RS01010	COG1176	ABC-type spermidine putrescine transport system, permease component I
CVS41_RS01015	COG1177	transmembrane transport
CVS41_RS01020	COG2258	MOSC domain
CVS41_RS01035	COG2050	protein possibly involved in aromatic compounds catabolism
CVS41_RS01040	COG0514	ATP-dependent DNA helicase (RecQ)
CVS41_RS01050	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CVS41_RS01060	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CVS41_RS01065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CVS41_RS01080	COG0254	rRNA binding
CVS41_RS01085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CVS41_RS01095	COG0702	epimerase
CVS41_RS01100	COG0814	amino acid
CVS41_RS01105	COG0281	malic enzyme
CVS41_RS01110	COG1295	ribonuclease BN
CVS41_RS01115	COG1490	D-aminoacyl-tRNA deacylase activity
CVS41_RS01120	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CVS41_RS01125	COG0456	acetyltransferase
CVS41_RS01135	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CVS41_RS01140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CVS41_RS01145	COG2610	gluconate transmembrane transporter activity
CVS41_RS01150	COG3265	gluconokinase activity
CVS41_RS01155	COG0129	dihydroxy-acid dehydratase activity
CVS41_RS01160	COG0800	Aldolase
CVS41_RS01165	COG1609	Transcriptional regulator
CVS41_RS01175	COG4942	peptidase
CVS41_RS01180	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CVS41_RS01185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CVS41_RS01190	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CVS41_RS01195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CVS41_RS01200	COG0316	Belongs to the HesB IscA family
CVS41_RS01200	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CVS41_RS01205	COG1040	competence protein
CVS41_RS01210	COG0596	Alpha beta hydrolase
CVS41_RS01230	COG2183	response to ionizing radiation
CVS41_RS01235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CVS41_RS01255	COG0051	transcription antitermination factor activity, RNA binding
CVS41_RS01260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CVS41_RS01265	COG0088	Forms part of the polypeptide exit tunnel
CVS41_RS01270	COG0089	rRNA binding
CVS41_RS01275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CVS41_RS01280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CVS41_RS01285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CVS41_RS01290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CVS41_RS01295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CVS41_RS01300	COG0255	Belongs to the universal ribosomal protein uL29 family
CVS41_RS01305	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CVS41_RS01310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CVS41_RS01315	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CVS41_RS01320	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CVS41_RS01325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CVS41_RS01330	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CVS41_RS01335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CVS41_RS01340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CVS41_RS01345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CVS41_RS01350	COG1841	ribosomal large subunit assembly
CVS41_RS01355	COG0200	Binds to the 23S rRNA
CVS41_RS01360	COG0201	protein transport
CVS41_RS01365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CVS41_RS01370	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CVS41_RS01375	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CVS41_RS01380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CVS41_RS01385	COG0202	RNA polymerase activity
CVS41_RS01390	COG0203	ribosomal protein L17
CVS41_RS01435	COG4771	TonB-dependent receptor
CVS41_RS01440	COG3706	GGDEF domain
CVS41_RS01465	COG0583	DNA-binding transcription factor activity
CVS41_RS01475	COG1741	Belongs to the pirin family
CVS41_RS01480	COG2259	Doxx family
CVS41_RS01485	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CVS41_RS01490	COG1074	ATP-dependent DNA helicase activity
CVS41_RS01495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CVS41_RS01540	COG1175	transmembrane transport
CVS41_RS01550	COG3842	ATPase activity
CVS41_RS01580	COG2873	o-acetylhomoserine
CVS41_RS01590	COG4533	DNA binding
CVS41_RS01610	COG5380	lipid catabolic process
CVS41_RS01615	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CVS41_RS01620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CVS41_RS01645	COG0753	catalase activity
CVS41_RS01650	COG0454	-acetyltransferase
CVS41_RS01650	COG0456	acetyltransferase
CVS41_RS01675	COG2927	DNA polymerase III (CHI subunit)
CVS41_RS01680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CVS41_RS01685	COG0795	lipopolysaccharide-transporting ATPase activity
CVS41_RS01690	COG0795	lipopolysaccharide-transporting ATPase activity
CVS41_RS01705	COG0582	viral genome integration into host DNA
CVS41_RS01750	COG4584	PFAM Integrase catalytic
CVS41_RS01755	COG1484	DNA-dependent DNA replication
CVS41_RS01790	COG2211	Major facilitator Superfamily
CVS41_RS01800	COG1172	Belongs to the binding-protein-dependent transport system permease family
CVS41_RS01810	COG1879	ABC-type sugar transport system periplasmic component
CVS41_RS01815	COG1069	ribulokinase activity
CVS41_RS01825	COG2160	L-arabinose isomerase activity
CVS41_RS01830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CVS41_RS01835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CVS41_RS01850	COG2017	converts alpha-aldose to the beta-anomer
CVS41_RS01895	COG1494	fructose-1,6-bisphosphatase
CVS41_RS01910	COG2959	enzyme of heme biosynthesis
CVS41_RS01920	COG0181	hydroxymethylbilane synthase activity
CVS41_RS01925	COG3072	Adenylate cyclase
CVS41_RS01930	COG0400	carboxylic ester hydrolase activity
CVS41_RS01935	COG1965	Belongs to the frataxin family
CVS41_RS01945	COG0019	diaminopimelate decarboxylase activity
CVS41_RS01950	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CVS41_RS01965	COG1011	Hydrolase
CVS41_RS01985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CVS41_RS01990	COG3028	Belongs to the UPF0307 family
CVS41_RS01995	COG0312	modulator of DNA gyrase
CVS41_RS02000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CVS41_RS02005	COG5007	Belongs to the BolA IbaG family
CVS41_RS02015	COG2854	intermembrane phospholipid transfer
CVS41_RS02020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CVS41_RS02025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CVS41_RS02030	COG1127	ABC transporter
CVS41_RS02035	COG0517	IMP dehydrogenase activity
CVS41_RS02035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CVS41_RS02040	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CVS41_RS02045	COG3117	lipopolysaccharide transmembrane transporter activity
CVS41_RS02050	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CVS41_RS02055	COG1137	ATPase activity
CVS41_RS02070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_RS02075	COG1660	Displays ATPase and GTPase activities
CVS41_RS02080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_RS02085	COG3711	transcriptional antiterminator
CVS41_RS02085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_RS02100	COG3964	amidohydrolase
CVS41_RS02130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CVS41_RS02135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CVS41_RS02145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CVS41_RS02150	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CVS41_RS02155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CVS41_RS02160	COG0723	plastoquinol--plastocyanin reductase activity
CVS41_RS02165	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CVS41_RS02170	COG2857	Cytochrome c1
CVS41_RS02175	COG0625	glutathione transferase activity
CVS41_RS02180	COG2969	positive regulation of protein catabolic process
CVS41_RS02185	COG2823	Periplasmic or secreted lipoprotein
CVS41_RS02190	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CVS41_RS02195	COG0792	nuclease activity
CVS41_RS02200	COG3107	peptidoglycan biosynthetic process
CVS41_RS02205	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CVS41_RS02215	COG2001	Belongs to the MraZ family
CVS41_RS02220	COG0275	rRNA processing
CVS41_RS02225	COG3116	cell division
CVS41_RS02230	COG0768	penicillin binding
CVS41_RS02240	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CVS41_RS02245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CVS41_RS02250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CVS41_RS02255	COG0772	Belongs to the SEDS family
CVS41_RS02260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CVS41_RS02265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CVS41_RS02275	COG0849	cell division
CVS41_RS02280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CVS41_RS02285	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CVS41_RS02295	COG0653	protein targeting
CVS41_RS02300	COG0494	nUDIX hydrolase
CVS41_RS02305	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CVS41_RS02310	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CVS41_RS02325	COG1459	type II secretion system
CVS41_RS02330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CVS41_RS02360	COG2186	Transcriptional regulator
CVS41_RS02365	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CVS41_RS02370	COG0508	dehydrogenase complex catalyzes the overall conversion of
CVS41_RS02375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CVS41_RS02385	COG0840	transmembrane signaling receptor activity
CVS41_RS02390	COG1752	Esterase of the alpha-beta hydrolase superfamily
CVS41_RS02395	COG1049	propionate catabolic process, 2-methylcitrate cycle
CVS41_RS02400	COG2200	EAL domain
CVS41_RS02410	COG0523	cobalamin synthesis protein
CVS41_RS02415	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_RS02430	COG0477	Major facilitator Superfamily
CVS41_RS02445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CVS41_RS02450	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CVS41_RS02475	COG3314	Sporulation integral membrane protein YlbJ
CVS41_RS02495	COG0165	Argininosuccinate lyase
CVS41_RS02500	COG0137	argininosuccinate synthase activity
CVS41_RS02510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CVS41_RS02515	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CVS41_RS02525	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CVS41_RS02540	COG3706	GGDEF domain
CVS41_RS02545	COG0814	amino acid
CVS41_RS02550	COG3932	Exopolysaccharide synthesis, ExoD
CVS41_RS02560	COG3706	GGDEF domain
CVS41_RS02565	COG0004	ammonium transporteR
CVS41_RS02570	COG3133	Outer membrane lipoprotein
CVS41_RS02575	COG0456	acetyltransferase
CVS41_RS02595	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CVS41_RS02600	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CVS41_RS02615	COG0671	phosphoesterase, PA-phosphatase related
CVS41_RS02620	COG0628	permease
CVS41_RS02635	COG3284	Transcriptional regulator
CVS41_RS02645	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CVS41_RS02645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CVS41_RS02645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_RS02650	COG1461	Dihydroxyacetone kinase
CVS41_RS02655	COG2376	Dihydroxyacetone kinase
CVS41_RS02660	COG2252	PERMEase
CVS41_RS02665	COG1278	Cold shock
CVS41_RS02675	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CVS41_RS02695	COG2197	response regulator
CVS41_RS02730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CVS41_RS02735	COG2199	diguanylate cyclase activity
CVS41_RS02740	COG3047	cAMP biosynthetic process
CVS41_RS02745	COG0840	transmembrane signaling receptor activity
CVS41_RS02775	COG1396	sequence-specific DNA binding
CVS41_RS02815	COG2926	Belongs to the UPF0265 family
CVS41_RS02825	COG0561	phosphatase activity
CVS41_RS02835	COG1058	Belongs to the CinA family
CVS41_RS02835	COG1546	Belongs to the CinA family
CVS41_RS02845	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CVS41_RS02855	COG1522	sequence-specific DNA binding
CVS41_RS02860	COG1368	sulfuric ester hydrolase activity
CVS41_RS02895	COG4221	oxidoreductase activity
CVS41_RS02910	COG1979	alcohol dehydrogenase
CVS41_RS02915	COG1803	Methylglyoxal synthase
CVS41_RS02935	COG1444	tRNA N-acetyltransferase activity
CVS41_RS02940	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_RS02945	COG0835	chemotaxis
CVS41_RS02945	COG0784	Response regulator, receiver
CVS41_RS02955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CVS41_RS02960	COG2949	membrane
CVS41_RS02965	COG3291	Pkd domain containing protein
CVS41_RS02970	COG0318	PFAM AMP-dependent synthetase and ligase
CVS41_RS02975	COG1441	menaquinone biosynthetic process
CVS41_RS02980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CVS41_RS02985	COG0596	Alpha beta hydrolase
CVS41_RS02990	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CVS41_RS02995	COG1169	isochorismate synthase
CVS41_RS03000	COG1575	Belongs to the MenA family. Type 1 subfamily
CVS41_RS03020	COG0513	Belongs to the DEAD box helicase family
CVS41_RS03025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CVS41_RS03030	COG1988	membrane-bound metal-dependent
CVS41_RS03035	COG1671	Belongs to the UPF0178 family
CVS41_RS03055	COG0484	heat shock protein binding
CVS41_RS03065	COG3722	fumarate hydratase activity
CVS41_RS03070	COG0246	Mannitol dehydrogenase
CVS41_RS03075	COG2213	PTS system mannitol-specific
CVS41_RS03075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_RS03080	COG1560	Kdo2-lipid A biosynthetic process
CVS41_RS03085	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CVS41_RS03085	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CVS41_RS03090	COG1538	Outer membrane efflux protein
CVS41_RS03095	COG0494	nUDIX hydrolase
CVS41_RS03100	COG3151	Protein conserved in bacteria
CVS41_RS03110	COG3150	esterase
CVS41_RS03130	COG3104	oligopeptide transport
CVS41_RS03160	COG2084	Dehydrogenase
CVS41_RS03165	COG0583	DNA-binding transcription factor activity
CVS41_RS03170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CVS41_RS03190	COG0204	Acyl-transferase
CVS41_RS03195	COG1842	Phage shock protein A
CVS41_RS03210	COG2827	Endonuclease containing a URI domain
CVS41_RS03225	COG1573	uracil-dna glycosylase
CVS41_RS03230	COG0697	spore germination
CVS41_RS03235	COG0583	DNA-binding transcription factor activity
CVS41_RS03240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CVS41_RS03245	COG1121	(ABC) transporter
CVS41_RS03250	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CVS41_RS03270	COG0739	heme binding
CVS41_RS03280	COG3068	Protein conserved in bacteria
CVS41_RS03300	COG0617	tRNA 3'-terminal CCA addition
CVS41_RS03305	COG1194	a g-specific adenine glycosylase
CVS41_RS03310	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CVS41_RS03320	COG3111	PFAM Bacterial OB fold (BOF) protein
CVS41_RS03325	COG3240	lipase activity
CVS41_RS03330	COG2885	chlorophyll binding
CVS41_RS03330	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CVS41_RS03335	COG3706	GGDEF domain
CVS41_RS03340	COG0557	exoribonuclease II activity
CVS41_RS03345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CVS41_RS03355	COG2153	protein acetylation
CVS41_RS03360	COG0513	Belongs to the DEAD box helicase family
CVS41_RS03365	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CVS41_RS03390	COG0735	belongs to the Fur family
CVS41_RS03395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CVS41_RS03400	COG0840	transmembrane signaling receptor activity
CVS41_RS03410	COG4166	transmembrane transport
CVS41_RS03430	COG1024	Enoyl-CoA hydratase
CVS41_RS03445	COG4221	oxidoreductase activity
CVS41_RS03450	COG0442	prolyl-tRNA aminoacylation
CVS41_RS03455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CVS41_RS03465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CVS41_RS03465	COG3008	intermembrane lipid transfer
CVS41_RS03470	COG2995	paraquat-inducible protein a
CVS41_RS03480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVS41_RS03490	COG3706	GGDEF domain
CVS41_RS03490	COG2203	Gaf domain
CVS41_RS03490	COG4251	negative regulation of phosphorylation
CVS41_RS03490	COG5001	Diguanylate cyclase
CVS41_RS03495	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CVS41_RS03510	COG2771	luxR family
CVS41_RS03520	COG0840	transmembrane signaling receptor activity
CVS41_RS03525	COG0632	four-way junction helicase activity
CVS41_RS03530	COG2255	four-way junction helicase activity
CVS41_RS03540	COG1294	oxidase, subunit
CVS41_RS03545	COG4890	Cyd operon protein YbgT
CVS41_RS03550	COG3790	cyd operon protein YbgE
CVS41_RS03555	COG0824	Thioesterase
CVS41_RS03560	COG0811	peptide transport
CVS41_RS03575	COG0823	Involved in the tonB-independent uptake of proteins
CVS41_RS03580	COG2885	chlorophyll binding
CVS41_RS03585	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CVS41_RS03630	COG0733	neurotransmitter:sodium symporter activity
CVS41_RS03640	COG0733	neurotransmitter:sodium symporter activity
CVS41_RS03655	COG0561	phosphatase activity
CVS41_RS03705	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CVS41_RS03710	COG1640	4-alpha-glucanotransferase
CVS41_RS03720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CVS41_RS03725	COG0676	glucose-6-phosphate 1-epimerase activity
CVS41_RS03730	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CVS41_RS03735	COG0840	transmembrane signaling receptor activity
CVS41_RS03740	COG1585	Membrane protein implicated in regulation of membrane protease activity
CVS41_RS03745	COG0330	HflC and HflK could
CVS41_RS03750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CVS41_RS03750	COG1648	precorrin-2 dehydrogenase activity
CVS41_RS03755	COG0175	sulfate reduction
CVS41_RS03760	COG2895	sulfate adenylyltransferase (ATP) activity
CVS41_RS03765	COG0471	metal ion transport
CVS41_RS03765	COG3273	potassium ion transport
CVS41_RS03770	COG0529	Catalyzes the synthesis of activated sulfate
CVS41_RS03780	COG0840	transmembrane signaling receptor activity
CVS41_RS03800	COG1136	(ABC) transporter
CVS41_RS03815	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CVS41_RS03830	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CVS41_RS03835	COG3437	response regulator, receiver
CVS41_RS03835	COG0784	Response regulator, receiver
CVS41_RS03845	COG2076	Multidrug Resistance protein
CVS41_RS03850	COG2076	Multidrug Resistance protein
CVS41_RS03855	COG0346	lactoylglutathione lyase activity
CVS41_RS03860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CVS41_RS03865	COG1643	Atp-dependent helicase
CVS41_RS03875	COG1489	DNA binding
CVS41_RS03880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CVS41_RS03885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CVS41_RS03895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CVS41_RS03900	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CVS41_RS03905	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CVS41_RS03915	COG1823	symporter activity
CVS41_RS03935	COG1924	4 iron, 4 sulfur cluster binding
CVS41_RS03940	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CVS41_RS03945	COG0842	Transport permease protein
CVS41_RS03950	COG1131	(ABC) transporter
CVS41_RS03965	COG0163	prenyltransferase activity
CVS41_RS03970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CVS41_RS03975	COG0671	phosphoesterase, PA-phosphatase related
CVS41_RS03980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CVS41_RS03985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVS41_RS03990	COG1151	hydroxylamine reductase activity
CVS41_RS03995	COG0783	Belongs to the Dps family
CVS41_RS04000	COG3023	N-Acetylmuramoyl-L-alanine amidase
CVS41_RS04005	COG4807	Protein conserved in bacteria
CVS41_RS04015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CVS41_RS04020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CVS41_RS04025	COG3956	TIGRFAM MazG family protein
CVS41_RS04030	COG0504	CTP synthase activity
CVS41_RS04035	COG0148	phosphopyruvate hydratase activity
CVS41_RS04090	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CVS41_RS04100	COG0488	(ABC) transporter
CVS41_RS04105	COG0517	IMP dehydrogenase activity
CVS41_RS04105	COG0617	tRNA 3'-terminal CCA addition
CVS41_RS04105	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CVS41_RS04120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVS41_RS04135	COG1794	racemase activity, acting on amino acids and derivatives
CVS41_RS04145	COG2731	YhcH YjgK YiaL family protein
CVS41_RS04155	COG0668	transmembrane transport
CVS41_RS04160	COG1376	ErfK ybiS ycfS ynhG family protein
CVS41_RS04170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CVS41_RS04175	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CVS41_RS04180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CVS41_RS04190	COG0585	pseudouridine synthase activity
CVS41_RS04195	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CVS41_RS04200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CVS41_RS04205	COG1238	metal cluster binding
CVS41_RS04220	COG1902	pentaerythritol trinitrate reductase activity
CVS41_RS04235	COG2957	Belongs to the agmatine deiminase family
CVS41_RS04240	COG0154	amidase activity
CVS41_RS04260	COG0513	Belongs to the DEAD box helicase family
CVS41_RS04265	COG2203	Gaf domain
CVS41_RS04265	COG2199	diguanylate cyclase activity
CVS41_RS04275	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
CVS41_RS04280	COG1858	cytochrome C peroxidase
CVS41_RS04325	COG2816	NAD+ diphosphatase activity
CVS41_RS04335	COG4191	Histidine kinase
CVS41_RS04360	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CVS41_RS04370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CVS41_RS04375	COG4991	sh3 domain protein
CVS41_RS04385	COG2816	NAD+ diphosphatase activity
CVS41_RS04390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CVS41_RS04395	COG1940	carbohydrate kinase activity
CVS41_RS04400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CVS41_RS04405	COG0126	phosphoglycerate kinase activity
CVS41_RS04410	COG0191	fructose-bisphosphate aldolase activity
CVS41_RS04415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVS41_RS04460	COG0354	folic acid binding
CVS41_RS04465	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CVS41_RS04475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CVS41_RS04480	COG1595	DNA-templated transcription, initiation
CVS41_RS04485	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CVS41_RS04490	COG3026	antisigma factor binding
CVS41_RS04500	COG0481	GTPase activity
CVS41_RS04505	COG0681	Belongs to the peptidase S26 family
CVS41_RS04520	COG1381	Involved in DNA repair and RecF pathway recombination
CVS41_RS04525	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CVS41_RS04535	COG2350	Protein conserved in bacteria
CVS41_RS04540	COG2917	probably involved in intracellular septation
CVS41_RS04545	COG0076	glutamate decarboxylase activity
CVS41_RS04550	COG1272	protein, Hemolysin III
CVS41_RS04555	COG0569	domain protein
CVS41_RS04555	COG2985	domain, Protein
CVS41_RS04575	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CVS41_RS04600	COG2313	pseudouridylate synthase activity
CVS41_RS04605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CVS41_RS04645	COG1765	OsmC-like protein
CVS41_RS04660	COG3954	Phosphoribulokinase
CVS41_RS04665	COG3089	Belongs to the UPF0270 family
CVS41_RS04670	COG5001	Diguanylate cyclase
CVS41_RS04670	COG4251	negative regulation of phosphorylation
CVS41_RS04670	COG3706	GGDEF domain
CVS41_RS04670	COG2203	Gaf domain
CVS41_RS04675	COG0429	hydrolase of the alpha beta-hydrolase fold
CVS41_RS04680	COG0784	Response regulator, receiver
CVS41_RS04680	COG0835	chemotaxis
CVS41_RS04690	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CVS41_RS04695	COG1047	Peptidyl-prolyl cis-trans
CVS41_RS04715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CVS41_RS04725	COG3340	Belongs to the peptidase S51 family
CVS41_RS04740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVS41_RS04750	COG3721	Heme iron utilization protein
CVS41_RS04755	COG0748	coenzyme F420 binding
CVS41_RS04780	COG2814	Major facilitator Superfamily
CVS41_RS04790	COG3655	Transcriptional regulator
CVS41_RS04800	COG5002	protein histidine kinase activity
CVS41_RS04800	COG2205	protein histidine kinase activity
CVS41_RS04800	COG0784	Response regulator, receiver
CVS41_RS04810	COG3706	GGDEF domain
CVS41_RS04870	COG0784	Response regulator, receiver
CVS41_RS04870	COG0835	chemotaxis
CVS41_RS04875	COG2755	lipolytic protein G-D-S-L family
CVS41_RS04880	COG4181	ATPase activity
CVS41_RS04885	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CVS41_RS04890	COG1090	epimerase
CVS41_RS04895	COG2200	EAL domain
CVS41_RS04900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVS41_RS04905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CVS41_RS04910	COG3171	Protein conserved in bacteria
CVS41_RS04915	COG2066	Belongs to the glutaminase family
CVS41_RS04920	COG2897	thiosulfate sulfurtransferase activity
CVS41_RS04935	COG0521	Mo-molybdopterin cofactor biosynthetic process
CVS41_RS04945	COG2966	Psort location CytoplasmicMembrane, score
CVS41_RS04950	COG3610	response to peptide
CVS41_RS04965	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CVS41_RS04970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CVS41_RS04980	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CVS41_RS04995	COG0786	glutamate:sodium symporter activity
CVS41_RS05000	COG0252	asparaginase activity
CVS41_RS05005	COG3139	Protein of unknown function (DUF1315)
CVS41_RS05025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CVS41_RS05030	COG0321	lipoyl(octanoyl) transferase activity
CVS41_RS05035	COG2921	Belongs to the UPF0250 family
CVS41_RS05040	COG1686	Belongs to the peptidase S11 family
CVS41_RS05045	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CVS41_RS05050	COG2951	lytic endotransglycosylase activity
CVS41_RS05055	COG0772	Belongs to the SEDS family
CVS41_RS05060	COG0768	penicillin binding
CVS41_RS05065	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CVS41_RS05070	COG0799	negative regulation of ribosome biogenesis
CVS41_RS05075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CVS41_RS05090	COG0495	leucyl-tRNA aminoacylation
CVS41_RS05095	COG2888	peptidyl-tyrosine sulfation
CVS41_RS05100	COG0312	modulator of DNA gyrase
CVS41_RS05110	COG0716	FMN binding
CVS41_RS05115	COG4974	Belongs to the 'phage' integrase family
CVS41_RS05120	COG1970	mechanosensitive ion channel activity
CVS41_RS05135	COG0789	Transcriptional regulator
CVS41_RS05140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CVS41_RS05145	COG4535	Mg2 and Co2 transporter CorC
CVS41_RS05150	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CVS41_RS05155	COG1702	phosphate starvation-inducible protein PhoH
CVS41_RS05160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CVS41_RS05165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CVS41_RS05170	COG1335	isochorismatase
CVS41_RS05175	COG3706	GGDEF domain
CVS41_RS05180	COG0583	DNA-binding transcription factor activity
CVS41_RS05200	COG3447	MASE1 domain protein
CVS41_RS05200	COG5002	protein histidine kinase activity
CVS41_RS05200	COG5001	Diguanylate cyclase
CVS41_RS05210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CVS41_RS05220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CVS41_RS05230	COG0516	GMP reductase activity
CVS41_RS05240	COG0642	Histidine kinase
CVS41_RS05255	COG4221	oxidoreductase activity
CVS41_RS05265	COG1022	Amp-dependent synthetase and ligase
CVS41_RS05280	COG3214	Protein conserved in bacteria
CVS41_RS05290	COG2195	Cleaves the N-terminal amino acid of tripeptides
CVS41_RS05295	COG0700	Nucleoside recognition
CVS41_RS05300	COG3366	ferrous iron transmembrane transporter activity
CVS41_RS05305	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CVS41_RS05310	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CVS41_RS05315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CVS41_RS05320	COG1053	succinate dehydrogenase
CVS41_RS05330	COG0584	glycerophosphoryl diester phosphodiesterase
CVS41_RS05335	COG1511	domain protein
CVS41_RS05335	COG3264	Mechanosensitive ion channel
CVS41_RS05345	COG0739	heme binding
CVS41_RS05355	COG0583	DNA-binding transcription factor activity
CVS41_RS05375	COG0583	DNA-binding transcription factor activity
CVS41_RS05380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CVS41_RS05410	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CVS41_RS05415	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CVS41_RS05425	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CVS41_RS05430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CVS41_RS05440	COG0180	Tryptophanyl-tRNA synthetase
CVS41_RS05450	COG0512	Glutamine amidotransferase of anthranilate synthase
CVS41_RS05455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CVS41_RS05465	COG1012	belongs to the aldehyde dehydrogenase family
CVS41_RS05480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVS41_RS05490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_RS05490	COG1013	pyruvate-flavodoxin oxidoreductase activity
CVS41_RS05490	COG0674	pyruvate-flavodoxin oxidoreductase activity
CVS41_RS05490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CVS41_RS05495	COG0366	Alpha amylase catalytic
CVS41_RS05505	COG0657	acetylesterase activity
CVS41_RS05520	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CVS41_RS05530	COG0471	metal ion transport
CVS41_RS05530	COG0490	domain, Protein
CVS41_RS05570	COG0012	GTP binding
CVS41_RS05575	COG0193	aminoacyl-tRNA hydrolase activity
CVS41_RS05580	COG0737	Belongs to the 5'-nucleotidase family
CVS41_RS05585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CVS41_RS05595	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CVS41_RS05600	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CVS41_RS05605	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CVS41_RS05610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CVS41_RS05615	COG2890	protein-(glutamine-N5) methyltransferase activity
CVS41_RS05625	COG2912	Transglutaminase-like superfamily
CVS41_RS05630	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CVS41_RS05645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CVS41_RS05655	COG3408	Glycogen debranching enzyme
CVS41_RS05655	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CVS41_RS05665	COG1881	PFAM PEBP family protein
CVS41_RS05670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CVS41_RS05685	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CVS41_RS05695	COG0583	DNA-binding transcription factor activity
CVS41_RS05700	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_RS05705	COG0616	signal peptide processing
CVS41_RS05710	COG2211	Major facilitator Superfamily
CVS41_RS05715	COG3706	GGDEF domain
CVS41_RS05720	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CVS41_RS05730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CVS41_RS05735	COG0826	peptidase U32
CVS41_RS05740	COG2200	EAL domain
CVS41_RS05740	COG2203	Gaf domain
CVS41_RS05740	COG2199	diguanylate cyclase activity
CVS41_RS05765	COG2197	response regulator
CVS41_RS05795	COG3724	N-succinylarginine dihydrolase activity
CVS41_RS05810	COG0840	transmembrane signaling receptor activity
CVS41_RS05820	COG2971	BadF BadG BcrA BcrD
CVS41_RS05830	COG4608	Belongs to the ABC transporter superfamily
CVS41_RS05835	COG0444	Belongs to the ABC transporter superfamily
CVS41_RS05840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVS41_RS05855	COG2205	protein histidine kinase activity
CVS41_RS05855	COG0784	Response regulator, receiver
CVS41_RS05885	COG3220	belongs to the UPF0276 family
CVS41_RS05915	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CVS41_RS05925	COG1289	transmembrane transporter activity
CVS41_RS05930	COG0303	'Molybdopterin
CVS41_RS05935	COG0746	molybdenum cofactor guanylyltransferase activity
CVS41_RS05945	COG4662	Binding-protein-dependent transport system inner membrane component
CVS41_RS05955	COG2204	response regulator
CVS41_RS05960	COG3852	Histidine kinase
CVS41_RS05970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CVS41_RS06005	COG3383	formate dehydrogenase (NAD+) activity
CVS41_RS06005	COG3383	formate dehydrogenase (NAD+) activity
CVS41_RS06010	COG0437	4 iron, 4 sulfur cluster binding
CVS41_RS06030	COG0281	malic enzyme
CVS41_RS06050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_RS06145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CVS41_RS06180	COG1857	crispr-associated protein
CVS41_RS06195	COG1518	maintenance of DNA repeat elements
CVS41_RS06200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CVS41_RS06240	COG0837	glucose binding
CVS41_RS06245	COG1737	Transcriptional regulator
CVS41_RS06250	COG0469	pyruvate kinase activity
CVS41_RS06270	COG1677	Flagellar hook-basal body complex protein FliE
CVS41_RS06280	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CVS41_RS06335	COG1684	flagellar biosynthetic protein fliR
CVS41_RS06345	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CVS41_RS06370	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CVS41_RS06375	COG0784	Response regulator, receiver
CVS41_RS06375	COG2198	Histidine kinase
CVS41_RS06375	COG0643	Histidine kinase
CVS41_RS06385	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CVS41_RS06390	COG1360	Flagellar Motor Protein
CVS41_RS06395	COG1192	Involved in chromosome partitioning
CVS41_RS06405	COG0835	chemotaxis
CVS41_RS06420	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CVS41_RS06425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CVS41_RS06430	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CVS41_RS06435	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CVS41_RS06440	COG1138	Cytochrome C-type biogenesis protein
CVS41_RS06445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CVS41_RS06450	COG4235	cytochrome complex assembly
CVS41_RS06450	COG3088	subunit of a heme lyase
CVS41_RS06460	COG2853	Lipoprotein
CVS41_RS06470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CVS41_RS06475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CVS41_RS06485	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CVS41_RS06490	COG1882	Formate acetyltransferase
CVS41_RS06500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CVS41_RS06500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CVS41_RS06530	COG0259	pyridoxamine-phosphate oxidase activity
CVS41_RS06555	COG2850	peptidyl-arginine hydroxylation
CVS41_RS06560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CVS41_RS06565	COG2915	High frequency lysogenization protein hflD homolog
CVS41_RS06570	COG0482	sulfurtransferase activity
CVS41_RS06580	COG1187	pseudouridine synthase activity
CVS41_RS06590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_RS06595	COG2271	Major facilitator Superfamily
CVS41_RS06600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_RS06600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_RS06600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_RS06625	COG0783	Belongs to the Dps family
CVS41_RS06655	COG1609	Transcriptional regulator
CVS41_RS06665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_RS06665	COG1263	PTS System
CVS41_RS06670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CVS41_RS06675	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CVS41_RS06685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_RS06690	COG1960	acyl-CoA dehydrogenase activity
CVS41_RS06700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CVS41_RS06710	COG0210	DNA helicase
CVS41_RS06725	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CVS41_RS06745	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CVS41_RS06795	COG1940	carbohydrate kinase activity
CVS41_RS06800	COG0457	Tetratricopeptide repeat
CVS41_RS06805	COG0477	Major facilitator Superfamily
CVS41_RS06805	COG2814	Major facilitator Superfamily
CVS41_RS06815	COG3383	formate dehydrogenase (NAD+) activity
CVS41_RS06825	COG0784	Response regulator, receiver
CVS41_RS06825	COG2205	protein histidine kinase activity
CVS41_RS06835	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CVS41_RS06840	COG2867	negative regulation of translational initiation
CVS41_RS06845	COG2914	Belongs to the UPF0125 (RnfH) family
CVS41_RS06850	COG1473	amidohydrolase
CVS41_RS06855	COG1960	acyl-CoA dehydrogenase activity
CVS41_RS06860	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CVS41_RS06865	COG0121	glutamine amidotransferase
CVS41_RS06895	COG2197	response regulator
CVS41_RS06900	COG3850	Histidine kinase
CVS41_RS06905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CVS41_RS06910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CVS41_RS06920	COG0243	molybdopterin cofactor binding
CVS41_RS06925	COG0437	4 iron, 4 sulfur cluster binding
CVS41_RS06930	COG0348	domain, Protein
CVS41_RS06940	COG3005	denitrification pathway
CVS41_RS06945	COG0521	Mo-molybdopterin cofactor biosynthetic process
CVS41_RS06950	COG0315	cyclic pyranopterin monophosphate synthase activity
CVS41_RS06955	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CVS41_RS06960	COG0314	molybdopterin synthase activity
CVS41_RS06975	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CVS41_RS06980	COG2267	carboxylic ester hydrolase activity
CVS41_RS06985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CVS41_RS06995	COG0302	gtp cyclohydrolase
CVS41_RS07000	COG0840	transmembrane signaling receptor activity
CVS41_RS07005	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CVS41_RS07015	COG0583	DNA-binding transcription factor activity
CVS41_RS07020	COG2353	YceI-like domain
CVS41_RS07030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CVS41_RS07045	COG2195	Cleaves the N-terminal amino acid of tripeptides
CVS41_RS07055	COG1166	arginine decarboxylase activity
CVS41_RS07065	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CVS41_RS07085	COG0814	amino acid
CVS41_RS07095	COG3681	Belongs to the UPF0597 family
CVS41_RS07100	COG2964	Protein conserved in bacteria
CVS41_RS07110	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CVS41_RS07115	COG1288	antiporter activity
CVS41_RS07120	COG0436	Aminotransferase
CVS41_RS07130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CVS41_RS07135	COG1196	nuclear chromosome segregation
CVS41_RS07135	COG0741	lytic transglycosylase activity
CVS41_RS07135	COG0739	heme binding
CVS41_RS07160	COG0788	formyltetrahydrofolate deformylase activity
CVS41_RS07165	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CVS41_RS07175	COG3118	belongs to the thioredoxin family
CVS41_RS07185	COG0791	NLP P60 protein
CVS41_RS07190	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CVS41_RS07200	COG0471	metal ion transport
CVS41_RS07210	COG1388	LysM domain
CVS41_RS07210	COG1376	ErfK ybiS ycfS ynhG family protein
CVS41_RS07220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_RS07225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_RS07230	COG0745	RESPONSE REGULATOR receiver
CVS41_RS07235	COG5000	phosphorelay sensor kinase activity
CVS41_RS07235	COG5002	protein histidine kinase activity
CVS41_RS07260	COG1388	LysM domain
CVS41_RS07260	COG0741	lytic transglycosylase activity
CVS41_RS07265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CVS41_RS07270	COG2226	methyltransferase
CVS41_RS07275	COG0328	RNA-DNA hybrid ribonuclease activity
CVS41_RS07280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CVS41_RS07290	COG3437	response regulator, receiver
CVS41_RS07290	COG0784	Response regulator, receiver
CVS41_RS07295	COG2375	cellular response to nickel ion
CVS41_RS07300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVS41_RS07305	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVS41_RS07310	COG1120	ATPase activity
CVS41_RS07315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CVS41_RS07325	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_RS07330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_RS07365	COG0708	Exodeoxyribonuclease III
CVS41_RS07395	COG3132	Protein of unknown function, DUF480
CVS41_RS07400	COG5001	Diguanylate cyclase
CVS41_RS07400	COG3300	MHYT domain
CVS41_RS07410	COG2841	Protein conserved in bacteria
CVS41_RS07420	COG0534	Mate efflux family protein
CVS41_RS07455	COG1309	transcriptional regulator
CVS41_RS07490	COG3152	Membrane
CVS41_RS07505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_RS07515	COG1482	cell wall glycoprotein biosynthetic process
CVS41_RS07520	COG2207	Transcriptional regulator
CVS41_RS07525	COG0538	isocitrate dehydrogenase activity
CVS41_RS07535	COG3048	D-serine ammonia-lyase activity
CVS41_RS07545	COG0583	DNA-binding transcription factor activity
CVS41_RS07555	COG0791	NLP P60 protein
CVS41_RS07560	COG0583	DNA-binding transcription factor activity
CVS41_RS07565	COG0450	alkyl hydroperoxide reductase
CVS41_RS07585	COG0500	methyltransferase
CVS41_RS07590	COG4106	trans-aconitate 2-methyltransferase activity
CVS41_RS07595	COG1801	Protein of unknown function DUF72
CVS41_RS07605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CVS41_RS07610	COG0217	transcriptional regulatory protein
CVS41_RS07615	COG1454	alcohol dehydrogenase
CVS41_RS07615	COG1012	belongs to the aldehyde dehydrogenase family
CVS41_RS07620	COG2095	MarC family integral membrane protein
CVS41_RS07630	COG0601	transmembrane transport
CVS41_RS07635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVS41_RS07650	COG0861	Integral membrane protein TerC family
CVS41_RS07655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CVS41_RS07685	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CVS41_RS07690	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVS41_RS07695	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CVS41_RS07700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CVS41_RS07705	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CVS41_RS07710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CVS41_RS07725	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CVS41_RS07730	COG0505	Belongs to the CarA family
CVS41_RS07735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CVS41_RS07745	COG0287	Prephenate dehydrogenase
CVS41_RS07745	COG1605	Chorismate mutase
CVS41_RS07750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVS41_RS07760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVS41_RS07765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVS41_RS07800	COG0537	adenosine 5'-monophosphoramidase activity
CVS41_RS07815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CVS41_RS07830	COG1301	dicarboxylic acid transport
CVS41_RS07845	COG2354	Protein conserved in bacteria
CVS41_RS07855	COG2233	PERMEase
CVS41_RS07860	COG3150	esterase
CVS41_RS07865	COG1252	NADH dehydrogenase
CVS41_RS07875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CVS41_RS07880	COG3300	MHYT domain
CVS41_RS07880	COG5001	Diguanylate cyclase
CVS41_RS07885	COG0446	pyridine nucleotide-disulphide oxidoreductase
CVS41_RS07895	COG2373	Large extracellular alpha-helical protein
CVS41_RS07900	COG4953	penicillin-binding protein 1C
CVS41_RS07915	COG0301	tRNA thio-modification
CVS41_RS07915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CVS41_RS07985	COG4310	Domain of unknown function (DUF2172)
CVS41_RS08000	COG2089	acid synthase
CVS41_RS08010	COG1083	cytidylyl-transferase
CVS41_RS08030	COG0318	PFAM AMP-dependent synthetase and ligase
CVS41_RS08045	COG1215	transferase activity, transferring glycosyl groups
CVS41_RS08055	COG0562	UDP-galactopyranose mutase
CVS41_RS08065	COG1216	Glycosyl transferase, family 2
CVS41_RS08085	COG2226	methyltransferase
CVS41_RS08090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CVS41_RS08095	COG1086	Polysaccharide biosynthesis protein
CVS41_RS08110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CVS41_RS08125	COG0346	lactoylglutathione lyase activity
CVS41_RS08130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CVS41_RS08135	COG4660	Part of a membrane complex involved in electron transport
CVS41_RS08140	COG4659	FMN binding
CVS41_RS08145	COG4658	electron transport chain
CVS41_RS08155	COG2878	Part of a membrane complex involved in electron transport
CVS41_RS08160	COG4657	Part of a membrane complex involved in electron transport
CVS41_RS08165	COG1403	HNH endonuclease
CVS41_RS08175	COG0346	lactoylglutathione lyase activity
CVS41_RS08185	COG1187	pseudouridine synthase activity
CVS41_RS08190	COG2807	transmembrane transport
CVS41_RS08195	COG0583	DNA-binding transcription factor activity
CVS41_RS08215	COG2979	Protein of unknown function (DUF533)
CVS41_RS08225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVS41_RS08235	COG1294	oxidase, subunit
CVS41_RS08255	COG3220	belongs to the UPF0276 family
CVS41_RS08270	COG2249	NAD(P)H dehydrogenase (quinone) activity
CVS41_RS08275	COG2814	Major facilitator Superfamily
CVS41_RS08285	COG0656	L-ascorbic acid biosynthetic process
CVS41_RS08300	COG0583	DNA-binding transcription factor activity
CVS41_RS08310	COG0840	transmembrane signaling receptor activity
CVS41_RS08315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CVS41_RS08320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CVS41_RS08325	COG2271	Major facilitator Superfamily
CVS41_RS08330	COG1349	DNA-binding transcription factor activity
CVS41_RS08340	COG0584	glycerophosphoryl diester phosphodiesterase
CVS41_RS08345	COG4574	serine-type endopeptidase inhibitor activity
CVS41_RS08350	COG3085	chromosome segregation
CVS41_RS08355	COG0583	DNA-binding transcription factor activity
CVS41_RS08365	COG1448	Aminotransferase
CVS41_RS08380	COG0658	competence protein
CVS41_RS08380	COG2333	competence protein COMEC
CVS41_RS08390	COG1663	tetraacyldisaccharide 4'-kinase activity
CVS41_RS08395	COG2835	tetraacyldisaccharide 4'-kinase activity
CVS41_RS08400	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CVS41_RS08405	COG2197	response regulator
CVS41_RS08410	COG0322	excinuclease ABC activity
CVS41_RS08435	COG0582	viral genome integration into host DNA
CVS41_RS08510	COG0367	asparagine synthase
CVS41_RS08520	COG4651	solute:proton antiporter activity
CVS41_RS08520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CVS41_RS08525	COG0647	UMP catabolic process
CVS41_RS08540	COG1902	pentaerythritol trinitrate reductase activity
CVS41_RS08545	COG1253	flavin adenine dinucleotide binding
CVS41_RS08555	COG0277	FAD linked oxidase domain protein
CVS41_RS08555	COG0247	lactate metabolic process
CVS41_RS08565	COG2050	protein possibly involved in aromatic compounds catabolism
CVS41_RS08575	COG2056	Na+-H+ antiporter family
CVS41_RS08580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CVS41_RS08585	COG0671	phosphoesterase, PA-phosphatase related
CVS41_RS08590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CVS41_RS08595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CVS41_RS08605	COG0101	tRNA pseudouridine synthase activity
CVS41_RS08610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CVS41_RS08615	COG0285	dihydrofolate synthase activity
CVS41_RS08620	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CVS41_RS08625	COG0393	Putative heavy-metal-binding
CVS41_RS08635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CVS41_RS08635	COG1648	precorrin-2 dehydrogenase activity
CVS41_RS08655	COG4667	esterase of the alpha-beta hydrolase superfamily
CVS41_RS08660	COG1619	proteins homologs of microcin C7 resistance protein MccF
CVS41_RS08665	COG1368	sulfuric ester hydrolase activity
CVS41_RS08675	COG0527	aspartate kinase activity
CVS41_RS08680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CVS41_RS08680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CVS41_RS08685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CVS41_RS08705	COG0596	Alpha beta hydrolase
CVS41_RS08720	COG0577	efflux transmembrane transporter activity
CVS41_RS08725	COG1136	(ABC) transporter
CVS41_RS08740	COG2814	Major facilitator Superfamily
CVS41_RS08765	COG0672	)-iron permease
CVS41_RS08800	COG0659	secondary active sulfate transmembrane transporter activity
CVS41_RS08815	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CVS41_RS08815	COG0392	lysyltransferase activity
CVS41_RS08825	COG2205	protein histidine kinase activity
CVS41_RS08830	COG0745	RESPONSE REGULATOR receiver
CVS41_RS08850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CVS41_RS08855	COG1278	Cold shock
CVS41_RS08860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CVS41_RS08865	COG0542	response to heat
CVS41_RS08870	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CVS41_RS08875	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CVS41_RS08880	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CVS41_RS08885	COG3134	Outer membrane lipoprotein
CVS41_RS08890	COG3706	GGDEF domain
CVS41_RS08895	COG0492	ferredoxin-NADP+ reductase activity
CVS41_RS08900	COG0686	Belongs to the AlaDH PNT family
CVS41_RS08910	COG1674	ftsk spoiiie
CVS41_RS08910	COG0531	amino acid
CVS41_RS08915	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CVS41_RS08920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CVS41_RS08925	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CVS41_RS08930	COG1286	toxin biosynthetic process
CVS41_RS08935	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CVS41_RS08945	COG0563	adenylate kinase activity
CVS41_RS08950	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CVS41_RS08960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CVS41_RS08975	COG3300	MHYT domain
CVS41_RS08975	COG5001	Diguanylate cyclase
CVS41_RS09025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CVS41_RS09030	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CVS41_RS09035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVS41_RS09050	COG0513	Belongs to the DEAD box helicase family
CVS41_RS09055	COG0386	Belongs to the glutathione peroxidase family
CVS41_RS09065	COG1181	Belongs to the D-alanine--D-alanine ligase family
CVS41_RS09070	COG0383	alpha-mannosidase activity
CVS41_RS09075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_RS09075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_RS09075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_RS09080	COG2188	Transcriptional regulator
CVS41_RS09085	COG1570	exodeoxyribonuclease VII activity
CVS41_RS09090	COG1874	Beta-galactosidase
CVS41_RS09090	COG0366	Alpha amylase catalytic
CVS41_RS09105	COG0517	IMP dehydrogenase activity
CVS41_RS09105	COG0516	GMP reductase activity
CVS41_RS09110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CVS41_RS09110	COG0519	Catalyzes the synthesis of GMP from XMP
CVS41_RS09150	COG1025	Belongs to the peptidase M16 family
CVS41_RS09155	COG2062	phosphohistidine phosphatase, SixA
CVS41_RS09165	COG0697	spore germination
CVS41_RS09170	COG4166	transmembrane transport
CVS41_RS09175	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CVS41_RS09180	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CVS41_RS09190	COG4591	ABC-type transport system involved in lipoprotein release permease component
CVS41_RS09195	COG1136	(ABC) transporter
CVS41_RS09200	COG4591	ABC-type transport system involved in lipoprotein release permease component
CVS41_RS09205	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CVS41_RS09220	COG0544	peptidyl-prolyl cis-trans isomerase activity
CVS41_RS09225	COG0740	serine-type endopeptidase activity
CVS41_RS09230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CVS41_RS09235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CVS41_RS09240	COG0776	regulation of translation
CVS41_RS09245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CVS41_RS09250	COG0488	(ABC) transporter
CVS41_RS09255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CVS41_RS09260	COG3162	membrane
CVS41_RS09275	COG1024	Enoyl-CoA hydratase
CVS41_RS09280	COG1115	amino acid carrier protein
CVS41_RS09295	COG2801	Transposase and inactivated derivatives
CVS41_RS09310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVS41_RS09320	COG3842	ATPase activity
CVS41_RS09325	COG1840	ABC-type Fe3 transport system, periplasmic component
CVS41_RS09335	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CVS41_RS09340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CVS41_RS09345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVS41_RS09360	COG3088	subunit of a heme lyase
CVS41_RS09360	COG4235	cytochrome complex assembly
CVS41_RS09370	COG1138	Cytochrome C-type biogenesis protein
CVS41_RS09375	COG3301	Polysulphide reductase, NrfD
CVS41_RS09380	COG0437	4 iron, 4 sulfur cluster binding
CVS41_RS09385	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CVS41_RS09400	COG0247	lactate metabolic process
CVS41_RS09405	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CVS41_RS09410	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CVS41_RS09415	COG3012	SEC-C Motif Domain Protein
CVS41_RS09420	COG0840	transmembrane signaling receptor activity
CVS41_RS09425	COG1940	carbohydrate kinase activity
CVS41_RS09425	COG1846	Transcriptional regulator
CVS41_RS09430	COG3148	PFAM DTW domain containing protein
CVS41_RS09435	COG0730	response to heat
CVS41_RS09440	COG0583	DNA-binding transcription factor activity
CVS41_RS09455	COG3593	DNA synthesis involved in DNA repair
CVS41_RS09490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CVS41_RS09495	COG1011	Hydrolase
CVS41_RS09510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CVS41_RS09515	COG2832	Protein of unknown function (DUF454)
CVS41_RS09520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CVS41_RS09530	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CVS41_RS09540	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CVS41_RS09555	COG1560	Kdo2-lipid A biosynthetic process
CVS41_RS09560	COG1560	Kdo2-lipid A biosynthetic process
CVS41_RS09585	COG0417	DNA replication proofreading
CVS41_RS09600	COG1451	nucleotide metabolic process
CVS41_RS09615	COG3069	C4-dicarboxylate transmembrane transporter activity
CVS41_RS09630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVS41_RS09630	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CVS41_RS09635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CVS41_RS09645	COG2985	domain, Protein
CVS41_RS09645	COG0569	domain protein
CVS41_RS09660	COG0556	nucleotide-excision repair
CVS41_RS09670	COG0586	Pfam SNARE associated Golgi protein
CVS41_RS09675	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CVS41_RS09680	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CVS41_RS09695	COG4681	YaeQ
CVS41_RS09710	COG3829	transcription factor binding
CVS41_RS09755	COG0307	riboflavin synthase, alpha
CVS41_RS09765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVS41_RS09770	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CVS41_RS09775	COG0697	spore germination
CVS41_RS09780	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CVS41_RS09820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CVS41_RS09825	COG3099	Belongs to the UPF0263 family
CVS41_RS09830	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CVS41_RS09835	COG2894	cell division
CVS41_RS09840	COG0850	regulation of cytokinetic process
CVS41_RS09845	COG3100	YcgL domain-containing protein
CVS41_RS09850	COG1760	l-serine dehydratase
CVS41_RS09860	COG1760	l-serine dehydratase
CVS41_RS09865	COG3123	guanosine phosphorylase activity
CVS41_RS09875	COG0205	6-phosphofructokinase activity
CVS41_RS09885	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CVS41_RS09890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CVS41_RS09900	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CVS41_RS09905	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CVS41_RS09925	COG0242	peptide deformylase activity
CVS41_RS09960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CVS41_RS09965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CVS41_RS09970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CVS41_RS09980	COG0549	Belongs to the carbamate kinase family
CVS41_RS09995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVS41_RS10005	COG0697	spore germination
CVS41_RS10015	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CVS41_RS10015	COG3608	succinylglutamate desuccinylase aspartoacylase
CVS41_RS10020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CVS41_RS10025	COG2068	MobA-Related Protein
CVS41_RS10030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CVS41_RS10030	COG0493	'glutamate synthase
CVS41_RS10035	COG0402	S-adenosylhomocysteine deaminase activity
CVS41_RS10040	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CVS41_RS10045	COG2080	2 iron, 2 sulfur cluster binding
CVS41_RS10045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CVS41_RS10050	COG2233	PERMEase
CVS41_RS10055	COG0402	S-adenosylhomocysteine deaminase activity
CVS41_RS10060	COG2252	PERMEase
CVS41_RS10065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CVS41_RS10070	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CVS41_RS10075	COG2080	2 iron, 2 sulfur cluster binding
CVS41_RS10080	COG3134	Outer membrane lipoprotein
CVS41_RS10095	COG0318	PFAM AMP-dependent synthetase and ligase
CVS41_RS10100	COG2199	diguanylate cyclase activity
CVS41_RS10115	COG0107	imidazoleglycerol-phosphate synthase activity
CVS41_RS10120	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CVS41_RS10125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CVS41_RS10130	COG0131	Imidazoleglycerol-phosphate dehydratase
CVS41_RS10130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CVS41_RS10135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CVS41_RS10140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CVS41_RS10145	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CVS41_RS10155	COG1199	ATP-dependent helicase activity
CVS41_RS10160	COG1214	PFAM Peptidase M22, glycoprotease
CVS41_RS10170	COG2267	carboxylic ester hydrolase activity
CVS41_RS10175	COG0318	PFAM AMP-dependent synthetase and ligase
CVS41_RS10185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CVS41_RS10190	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CVS41_RS10195	COG0709	Synthesizes selenophosphate from selenide and ATP
CVS41_RS10210	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CVS41_RS10215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CVS41_RS10225	COG0840	transmembrane signaling receptor activity
CVS41_RS10230	COG1254	Belongs to the acylphosphatase family
CVS41_RS10240	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVS41_RS10240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVS41_RS10245	COG0489	protein tyrosine kinase activity
CVS41_RS10250	COG0572	uridine kinase
CVS41_RS10255	COG0717	Belongs to the dCTP deaminase family
CVS41_RS10260	COG0306	phosphate transporter
CVS41_RS10265	COG3313	Fe-S protein
CVS41_RS10270	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CVS41_RS10275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVS41_RS10280	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CVS41_RS10285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CVS41_RS10295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CVS41_RS10305	COG0366	Alpha amylase catalytic
CVS41_RS10320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CVS41_RS10325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CVS41_RS10330	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CVS41_RS10335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CVS41_RS10340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CVS41_RS10345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVS41_RS10345	COG0072	phenylalanine-tRNA ligase activity
CVS41_RS10350	COG0776	regulation of translation
CVS41_RS10355	COG0784	Response regulator, receiver
CVS41_RS10355	COG2205	protein histidine kinase activity
CVS41_RS10380	COG3300	MHYT domain
CVS41_RS10380	COG5001	Diguanylate cyclase
CVS41_RS10385	COG1609	Transcriptional regulator
CVS41_RS10390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CVS41_RS10395	COG1879	ABC-type sugar transport system periplasmic component
CVS41_RS10400	COG1172	Belongs to the binding-protein-dependent transport system permease family
CVS41_RS10405	COG1129	ABC transporter
CVS41_RS10410	COG1869	D-ribose catabolic process
CVS41_RS10415	COG0625	glutathione transferase activity
CVS41_RS10430	COG1177	transmembrane transport
CVS41_RS10455	COG0037	tRNA processing
CVS41_RS10460	COG0589	response to stress
CVS41_RS10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CVS41_RS10480	COG2217	Heavy metal translocating P-type atpase
CVS41_RS10490	COG2010	Cytochrome c
CVS41_RS10505	COG3278	Belongs to the heme-copper respiratory oxidase family
CVS41_RS10515	COG1956	GAF domain-containing protein
CVS41_RS10520	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CVS41_RS10530	COG0308	aminopeptidase N
CVS41_RS10540	COG2902	Dehydrogenase
CVS41_RS10545	COG0167	dihydroorotate dehydrogenase activity
CVS41_RS10560	COG0254	rRNA binding
CVS41_RS10565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CVS41_RS10570	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CVS41_RS10570	COG0116	Belongs to the methyltransferase superfamily
CVS41_RS10580	COG0488	(ABC) transporter
CVS41_RS10590	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CVS41_RS10595	COG1067	ATP-dependent peptidase activity
CVS41_RS10620	COG3141	response to X-ray
CVS41_RS10625	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CVS41_RS10630	COG4221	oxidoreductase activity
CVS41_RS10675	COG0372	Belongs to the citrate synthase family
CVS41_RS10680	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CVS41_RS10690	COG2995	paraquat-inducible protein a
CVS41_RS10695	COG3008	intermembrane lipid transfer
CVS41_RS10700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CVS41_RS10700	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CVS41_RS10715	COG0084	hydrolase, TatD family'
CVS41_RS10720	COG0470	DNA polymerase III
CVS41_RS10725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CVS41_RS10730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CVS41_RS10735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CVS41_RS10740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CVS41_RS10745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CVS41_RS10750	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_RS10760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CVS41_RS10765	COG0416	fatty acid biosynthetic process
CVS41_RS10770	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CVS41_RS10775	COG1399	metal-binding, possibly nucleic acid-binding protein
CVS41_RS10780	COG0424	maF-like protein
CVS41_RS10795	COG1530	ribonuclease E activity
CVS41_RS10800	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CVS41_RS10800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_RS10800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_RS10805	COG1105	Belongs to the carbohydrate kinase PfkB family
CVS41_RS10810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_RS10810	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_RS10815	COG1609	Transcriptional regulator
CVS41_RS10820	COG0814	amino acid
CVS41_RS10850	COG0513	Belongs to the DEAD box helicase family
CVS41_RS10860	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CVS41_RS10865	COG2890	protein-(glutamine-N5) methyltransferase activity
CVS41_RS10870	COG2840	Smr protein MutS2
CVS41_RS10875	COG3706	GGDEF domain
CVS41_RS10880	COG0406	alpha-ribazole phosphatase activity
CVS41_RS10900	COG2824	Alkylphosphonate utilization operon protein PhnA
CVS41_RS10970	COG0494	nUDIX hydrolase
CVS41_RS10975	COG0814	amino acid
CVS41_RS10985	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CVS41_RS10990	COG0514	ATP-dependent DNA helicase (RecQ)
CVS41_RS10995	COG2766	serine protein kinase
CVS41_RS11000	COG2718	Belongs to the UPF0229 family
CVS41_RS11005	COG2719	SpoVR family
CVS41_RS11010	COG1250	3-hydroxyacyl-CoA dehydrogenase
CVS41_RS11010	COG1024	Enoyl-CoA hydratase
CVS41_RS11015	COG0183	Belongs to the thiolase family
CVS41_RS11020	COG0714	Associated with various cellular activities
CVS41_RS11040	COG2304	oxidoreductase activity
CVS41_RS11050	COG1595	DNA-templated transcription, initiation
CVS41_RS11060	COG2067	long-chain fatty acid transport protein
CVS41_RS11065	COG2067	long-chain fatty acid transport protein
CVS41_RS11070	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CVS41_RS11085	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CVS41_RS11095	COG1643	Atp-dependent helicase
CVS41_RS11100	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CVS41_RS11100	COG0617	tRNA 3'-terminal CCA addition
CVS41_RS11100	COG0517	IMP dehydrogenase activity
CVS41_RS11105	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CVS41_RS11110	COG3119	arylsulfatase activity
CVS41_RS11115	COG0714	Associated with various cellular activities
CVS41_RS11130	COG2304	oxidoreductase activity
CVS41_RS11135	COG2304	oxidoreductase activity
CVS41_RS11160	COG0641	radical SAM
CVS41_RS11175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVS41_RS11220	COG2925	Exonuclease
CVS41_RS11230	COG3345	alpha-galactosidase
CVS41_RS11235	COG1380	Effector of murein hydrolase LrgA
CVS41_RS11240	COG1346	cytolysis
CVS41_RS11245	COG0295	cytidine deaminase activity
CVS41_RS11250	COG3033	Beta-eliminating lyase
CVS41_RS11260	COG3046	protein related to deoxyribodipyrimidine photolyase
CVS41_RS11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVS41_RS11270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CVS41_RS11295	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CVS41_RS11315	COG0454	-acetyltransferase
CVS41_RS11325	COG3158	transport of potassium into the cell
CVS41_RS11330	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CVS41_RS11335	COG0651	ATP synthesis coupled electron transport
CVS41_RS11340	COG0650	Formate hydrogenlyase subunit 4
CVS41_RS11345	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CVS41_RS11345	COG3261	NADH dehydrogenase
CVS41_RS11350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_RS11355	COG3260	NADH ubiquinone oxidoreductase 20
CVS41_RS11365	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CVS41_RS11370	COG1921	L-seryl-tRNASec selenium transferase activity
CVS41_RS11380	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CVS41_RS11385	COG0298	carbon dioxide binding
CVS41_RS11395	COG0309	Hydrogenase expression formation protein (HypE)
CVS41_RS11400	COG0375	protein maturation
CVS41_RS11405	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CVS41_RS11410	COG1124	(ABC) transporter
CVS41_RS11420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVS41_RS11425	COG0601	transmembrane transport
CVS41_RS11435	COG1773	rubredoxin
CVS41_RS11440	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CVS41_RS11445	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CVS41_RS11450	COG5557	Pfam Polysulphide reductase, NrfD
CVS41_RS11455	COG0437	4 iron, 4 sulfur cluster binding
CVS41_RS11460	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CVS41_RS11465	COG2203	Gaf domain
CVS41_RS11465	COG4251	negative regulation of phosphorylation
CVS41_RS11465	COG3706	GGDEF domain
CVS41_RS11465	COG5001	Diguanylate cyclase
CVS41_RS11470	COG0438	transferase activity, transferring glycosyl groups
CVS41_RS11475	COG0438	transferase activity, transferring glycosyl groups
CVS41_RS11495	COG0438	transferase activity, transferring glycosyl groups
CVS41_RS11540	COG0438	transferase activity, transferring glycosyl groups
CVS41_RS11545	COG1215	transferase activity, transferring glycosyl groups
CVS41_RS11550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CVS41_RS11590	COG0784	Response regulator, receiver
CVS41_RS11590	COG2205	protein histidine kinase activity
CVS41_RS11605	COG0730	response to heat
CVS41_RS11615	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_RS11625	COG1024	Enoyl-CoA hydratase
CVS41_RS11630	COG1024	Enoyl-CoA hydratase
CVS41_RS11635	COG1960	acyl-CoA dehydrogenase activity
CVS41_RS11640	COG1960	acyl-CoA dehydrogenase activity
CVS41_RS11645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CVS41_RS11650	COG1024	Enoyl-CoA hydratase
CVS41_RS11680	COG1584	GPR1 FUN34 yaaH family protein
CVS41_RS11695	COG0045	succinate-CoA ligase (ADP-forming) activity
CVS41_RS11700	COG0508	dehydrogenase complex catalyzes the overall conversion of
CVS41_RS11705	COG0567	Dehydrogenase, E1 component
CVS41_RS11715	COG1053	succinate dehydrogenase
CVS41_RS11720	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CVS41_RS11725	COG2009	succinate dehydrogenase
CVS41_RS11760	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CVS41_RS11775	COG2501	S4 domain
CVS41_RS11785	COG1132	(ABC) transporter
CVS41_RS11790	COG1132	(ABC) transporter
CVS41_RS11800	COG3118	belongs to the thioredoxin family
CVS41_RS11805	COG0471	metal ion transport
CVS41_RS11810	COG0058	SHG alpha-glucan phosphorylase activity
CVS41_RS11825	COG2983	Belongs to the UPF0260 family
CVS41_RS11835	COG1882	Formate acetyltransferase
CVS41_RS11840	COG2116	formate transmembrane transporter activity
CVS41_RS11845	COG1944	ATP diphosphatase activity
CVS41_RS11850	COG2723	6-phospho-beta-galactosidase activity
CVS41_RS11855	COG0583	DNA-binding transcription factor activity
CVS41_RS11865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CVS41_RS11870	COG0583	DNA-binding transcription factor activity
CVS41_RS11880	COG1335	isochorismatase
CVS41_RS11890	COG2271	Major facilitator Superfamily
CVS41_RS11895	COG0583	DNA-binding transcription factor activity
CVS41_RS11900	COG0583	DNA-binding transcription factor activity
CVS41_RS11905	COG2910	NAD(P)H-binding
CVS41_RS11935	COG0861	Integral membrane protein TerC family
CVS41_RS11940	COG2885	chlorophyll binding
CVS41_RS11945	COG2199	diguanylate cyclase activity
CVS41_RS11960	COG2154	pterin-4-alpha-carbinolamine dehydratase
CVS41_RS11970	COG1012	belongs to the aldehyde dehydrogenase family
CVS41_RS11975	COG1177	transmembrane transport
CVS41_RS11980	COG1176	ABC-type spermidine putrescine transport system, permease component I
CVS41_RS11985	COG3842	ATPase activity
CVS41_RS11990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CVS41_RS11995	COG0583	DNA-binding transcription factor activity
CVS41_RS12000	COG3768	UPF0283 membrane protein
CVS41_RS12005	COG3106	COG3106 Predicted ATPase
CVS41_RS12020	COG1842	Phage shock protein A
CVS41_RS12025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CVS41_RS12035	COG4168	peptide transport system, permease
CVS41_RS12045	COG4172	Belongs to the ABC transporter superfamily
CVS41_RS12050	COG4172	Belongs to the ABC transporter superfamily
CVS41_RS12055	COG0326	Molecular chaperone. Has ATPase activity
CVS41_RS12060	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CVS41_RS12080	COG1435	thymidine kinase activity
CVS41_RS12085	COG1757	Na H antiporter
CVS41_RS12090	COG2916	Histone family protein nucleoid-structuring protein H-NS
CVS41_RS12095	COG2096	Adenosyltransferase
CVS41_RS12100	COG3530	Putative quorum-sensing-regulated virulence factor
CVS41_RS12105	COG0602	queuosine metabolic process
CVS41_RS12110	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CVS41_RS12130	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CVS41_RS12140	COG0776	regulation of translation
CVS41_RS12145	COG0539	negative regulation of cytoplasmic translation
CVS41_RS12150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CVS41_RS12155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CVS41_RS12160	COG0583	DNA-binding transcription factor activity
CVS41_RS12170	COG2814	Major facilitator Superfamily
CVS41_RS12190	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CVS41_RS12195	COG3300	MHYT domain
CVS41_RS12195	COG5001	Diguanylate cyclase
CVS41_RS12200	COG0583	DNA-binding transcription factor activity
CVS41_RS12205	COG3437	response regulator, receiver
CVS41_RS12230	COG4989	oxidoreductase activity
CVS41_RS12235	COG0724	RNA recognition motif
CVS41_RS12245	COG1126	abc transporter atp-binding protein
CVS41_RS12250	COG0765	amino acid transport
CVS41_RS12260	COG4597	amino acid ABC transporter
CVS41_RS12265	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CVS41_RS12275	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CVS41_RS12290	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CVS41_RS12295	COG1360	Flagellar Motor Protein
CVS41_RS12300	COG4771	TonB-dependent receptor
CVS41_RS12305	COG1770	oligopeptidase
CVS41_RS12325	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_RS12330	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_RS12335	COG0649	NAD binding
CVS41_RS12335	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_RS12350	COG1034	ATP synthesis coupled electron transport
CVS41_RS12355	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CVS41_RS12360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_RS12365	COG0839	Belongs to the complex I subunit 6 family
CVS41_RS12370	COG0713	ATP synthesis coupled electron transport
CVS41_RS12380	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_RS12385	COG1007	ATP synthesis coupled electron transport
CVS41_RS12400	COG2199	diguanylate cyclase activity
CVS41_RS12400	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CVS41_RS12405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CVS41_RS12405	COG0047	phosphoribosylformylglycinamidine synthase activity
CVS41_RS12410	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CVS41_RS12420	COG1645	bacterial-type flagellum-dependent swarming motility
CVS41_RS12425	COG1160	GTP binding
CVS41_RS12430	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVS41_RS12435	COG2976	Protein conserved in bacteria
CVS41_RS12440	COG0124	histidyl-tRNA synthetase
CVS41_RS12445	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CVS41_RS12460	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CVS41_RS12465	COG0105	UTP biosynthetic process
CVS41_RS12480	COG0633	Ferredoxin
CVS41_RS12485	COG0443	Heat shock 70 kDa protein
CVS41_RS12490	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CVS41_RS12500	COG0822	iron-sulfur transferase activity
CVS41_RS12505	COG1104	cysteine desulfurase activity
CVS41_RS12525	COG3154	lipid carrier protein
CVS41_RS12530	COG0826	peptidase U32
CVS41_RS12535	COG0826	peptidase U32
CVS41_RS12550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVS41_RS12555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVS41_RS12560	COG1862	Preprotein translocase
CVS41_RS12565	COG0343	queuine tRNA-ribosyltransferase activity
CVS41_RS12570	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CVS41_RS12575	COG0517	IMP dehydrogenase activity
CVS41_RS12585	COG3634	alkyl hydroperoxide reductase activity
CVS41_RS12635	COG1242	4 iron, 4 sulfur cluster binding
CVS41_RS12640	COG0067	glutamate synthase
CVS41_RS12640	COG0070	glutamate synthase
CVS41_RS12640	COG0069	glutamate synthase activity
CVS41_RS12645	COG0493	'glutamate synthase
CVS41_RS12660	COG0513	Belongs to the DEAD box helicase family
CVS41_RS12685	COG0023	Translation Initiation Factor
CVS41_RS12690	COG2119	membrane
CVS41_RS12735	COG0215	cysteine-tRNA ligase activity
CVS41_RS12740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CVS41_RS12750	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CVS41_RS12760	COG2261	transglycosylase associated protein
CVS41_RS12765	COG0642	Histidine kinase
CVS41_RS12790	COG0625	glutathione transferase activity
CVS41_RS12800	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CVS41_RS12815	COG0564	pseudouridine synthase activity
CVS41_RS12820	COG4160	amino acid transport
CVS41_RS12830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_RS12840	COG2431	L-lysine efflux transmembrane transporter activity
CVS41_RS12845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CVS41_RS12850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_RS12855	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CVS41_RS12865	COG1393	Belongs to the ArsC family
CVS41_RS12875	COG4783	chaperone-mediated protein folding
CVS41_RS12905	COG3842	ATPase activity
CVS41_RS12910	COG3833	ABC-type maltose transport systems, permease component
CVS41_RS12915	COG1175	transmembrane transport
CVS41_RS12925	COG3081	Nucleoid-associated protein
CVS41_RS12930	COG3082	Protein of unknown function (DUF1414)
CVS41_RS12935	COG3083	sulfuric ester hydrolase activity
CVS41_RS12940	COG1464	Belongs to the NlpA lipoprotein family
CVS41_RS12955	COG0574	Belongs to the PEP-utilizing enzyme family
CVS41_RS12955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CVS41_RS12960	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CVS41_RS12985	COG0840	transmembrane signaling receptor activity
CVS41_RS12990	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CVS41_RS12990	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CVS41_RS12995	COG0509	glycine decarboxylation via glycine cleavage system
CVS41_RS13000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CVS41_RS13005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CVS41_RS13010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CVS41_RS13030	COG2814	Major facilitator Superfamily
CVS41_RS13035	COG0625	glutathione transferase activity
CVS41_RS13045	COG0483	inositol monophosphate 1-phosphatase activity
CVS41_RS13090	COG1199	ATP-dependent helicase activity
CVS41_RS13100	COG0123	including yeast histone deacetylase and acetoin utilization protein
CVS41_RS13105	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CVS41_RS13110	COG1785	Belongs to the alkaline phosphatase family
CVS41_RS13130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CVS41_RS13135	COG2197	response regulator
CVS41_RS13145	COG2271	Major facilitator Superfamily
CVS41_RS13150	COG3706	GGDEF domain
CVS41_RS13155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_RS13160	COG0765	amino acid transport
CVS41_RS13165	COG1126	abc transporter atp-binding protein
CVS41_RS13180	COG0531	amino acid
CVS41_RS13195	COG1253	flavin adenine dinucleotide binding
CVS41_RS13200	COG0704	Plays a role in the regulation of phosphate uptake
CVS41_RS13205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CVS41_RS13210	COG0581	inorganic phosphate transmembrane transporter activity
CVS41_RS13215	COG0573	inorganic phosphate transmembrane transporter activity
CVS41_RS13220	COG0590	tRNA wobble adenosine to inosine editing
CVS41_RS13230	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CVS41_RS13250	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CVS41_RS13255	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CVS41_RS13260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CVS41_RS13265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CVS41_RS13290	COG2716	regulation of RNA biosynthetic process
CVS41_RS13295	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CVS41_RS13305	COG2239	Acts as a magnesium transporter
CVS41_RS13310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CVS41_RS13325	COG1706	bacterial-type flagellum-dependent cell motility
CVS41_RS13330	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CVS41_RS13340	COG4787	bacterial-type flagellum-dependent cell motility
CVS41_RS13360	COG1815	bacterial-type flagellum-dependent cell motility
CVS41_RS13365	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CVS41_RS13370	COG0784	Response regulator, receiver
CVS41_RS13370	COG0835	chemotaxis
CVS41_RS13375	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CVS41_RS13390	COG0622	Phosphoesterase
CVS41_RS13395	COG4166	transmembrane transport
CVS41_RS13405	COG1187	pseudouridine synthase activity
CVS41_RS13410	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CVS41_RS13420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CVS41_RS13425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CVS41_RS13430	COG1882	Formate acetyltransferase
CVS41_RS13435	COG1349	DNA-binding transcription factor activity
CVS41_RS13440	COG4166	transmembrane transport
CVS41_RS13465	COG1278	Cold shock
CVS41_RS13490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CVS41_RS13490	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CVS41_RS13495	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_RS13500	COG1535	isochorismatase
CVS41_RS13500	COG3433	isochorismatase activity
CVS41_RS13505	COG1021	2,3-dihydroxybenzoate-AMP ligase
CVS41_RS13510	COG1169	isochorismate synthase
CVS41_RS13515	COG4771	TonB-dependent receptor
CVS41_RS13520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVS41_RS13530	COG0741	lytic transglycosylase activity
CVS41_RS13540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CVS41_RS13560	COG2911	Protein conserved in bacteria
CVS41_RS13565	COG0729	surface antigen
CVS41_RS13575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CVS41_RS13585	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CVS41_RS13595	COG4134	Bacterial extracellular solute-binding protein
CVS41_RS13605	COG4136	ATPase activity
CVS41_RS13610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CVS41_RS13615	COG2951	lytic endotransglycosylase activity
CVS41_RS13620	COG1846	Transcriptional regulator
CVS41_RS13630	COG0033	Phosphoglucomutase
CVS41_RS13635	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CVS41_RS13640	COG0596	Alpha beta hydrolase
CVS41_RS13655	COG0716	FMN binding
CVS41_RS13665	COG0735	belongs to the Fur family
CVS41_RS13670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CVS41_RS13680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_RS13680	COG1263	PTS System
CVS41_RS13680	COG2190	(PTS) system
CVS41_RS13685	COG0363	glucosamine-6-phosphate deaminase activity
CVS41_RS13690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CVS41_RS13695	COG1846	Transcriptional regulator
CVS41_RS13695	COG1940	carbohydrate kinase activity
CVS41_RS13705	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CVS41_RS13705	COG2199	diguanylate cyclase activity
CVS41_RS13710	COG3275	phosphorelay sensor kinase activity
CVS41_RS13715	COG3279	Response regulator of the LytR AlgR family
CVS41_RS13720	COG1966	Carbon starvation protein
CVS41_RS13730	COG1566	PFAM secretion protein HlyD family protein
CVS41_RS13735	COG1061	Type III restriction enzyme res subunit
CVS41_RS13740	COG2027	D-alanyl-D-alanine carboxypeptidase
CVS41_RS13745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CVS41_RS13750	COG3021	interspecies interaction between organisms
CVS41_RS13760	COG1607	acyl-coa hydrolase
CVS41_RS13765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CVS41_RS13770	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CVS41_RS13770	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CVS41_RS13770	COG1013	pyruvate-flavodoxin oxidoreductase activity
CVS41_RS13770	COG0674	pyruvate-flavodoxin oxidoreductase activity
CVS41_RS13785	COG3217	Mosc domain protein beta barrel domain protein
CVS41_RS13785	COG0633	Ferredoxin
CVS41_RS13785	COG3217	Mosc domain protein beta barrel domain protein
CVS41_RS13785	COG0633	Ferredoxin
CVS41_RS13795	COG0501	Belongs to the peptidase M48B family
CVS41_RS13800	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CVS41_RS13805	COG1073	alpha beta
CVS41_RS13805	COG2226	methyltransferase
CVS41_RS13810	COG0156	8-amino-7-oxononanoate synthase activity
CVS41_RS13815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CVS41_RS13820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CVS41_RS13835	COG0017	Asparaginyl-tRNA synthetase
CVS41_RS13845	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CVS41_RS13855	COG1473	amidohydrolase
CVS41_RS13860	COG3069	C4-dicarboxylate transmembrane transporter activity
CVS41_RS13870	COG1393	Belongs to the ArsC family
CVS41_RS13875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CVS41_RS13880	COG1876	peptidase activity
CVS41_RS13890	COG3263	regulation of cellular component size
CVS41_RS13905	COG1280	lysine exporter protein (LysE YggA)
CVS41_RS13940	COG0564	pseudouridine synthase activity
CVS41_RS13950	COG1454	alcohol dehydrogenase
CVS41_RS13955	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVS41_RS13960	COG0702	epimerase
CVS41_RS13970	COG0095	Lipoate-protein ligase
CVS41_RS13980	COG1136	(ABC) transporter
CVS41_RS13980	COG0577	efflux transmembrane transporter activity
CVS41_RS13985	COG0577	efflux transmembrane transporter activity
CVS41_RS13985	COG1136	(ABC) transporter
CVS41_RS13990	COG1136	(ABC) transporter
CVS41_RS13990	COG0577	efflux transmembrane transporter activity
CVS41_RS13995	COG1566	PFAM secretion protein HlyD family protein
CVS41_RS14010	COG2391	methyltransferase activity
CVS41_RS14030	COG0446	pyridine nucleotide-disulphide oxidoreductase
CVS41_RS14040	COG1285	pathogenesis
CVS41_RS14070	COG0484	heat shock protein binding
CVS41_RS14075	COG0443	Heat shock 70 kDa protein
CVS41_RS14080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CVS41_RS14085	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CVS41_RS14090	COG0497	DNA recombination
CVS41_RS14100	COG1227	inorganic diphosphatase activity
CVS41_RS14105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_RS14110	COG0577	efflux transmembrane transporter activity
CVS41_RS14110	COG1136	(ABC) transporter
CVS41_RS14130	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVS41_RS14150	COG3206	protein involved in exopolysaccharide biosynthesis
CVS41_RS14150	COG0489	protein tyrosine kinase activity
CVS41_RS14155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CVS41_RS14160	COG1596	polysaccharide export
CVS41_RS14190	COG0438	transferase activity, transferring glycosyl groups
CVS41_RS14190	COG0297	glycogen (starch) synthase activity
CVS41_RS14195	COG0438	transferase activity, transferring glycosyl groups
CVS41_RS14215	COG2244	polysaccharide biosynthetic process
CVS41_RS14230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CVS41_RS14250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CVS41_RS14285	COG1091	dTDP-4-dehydrorhamnose reductase activity
CVS41_RS14295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_RS14300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_RS14305	COG1309	transcriptional regulator
CVS41_RS14320	COG1342	Belongs to the UPF0251 family
CVS41_RS14340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CVS41_RS14360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CVS41_RS14365	COG0083	homoserine kinase activity
CVS41_RS14380	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CVS41_RS14385	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CVS41_RS14390	COG1946	Acyl-CoA thioesterase
CVS41_RS14400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CVS41_RS14410	COG0009	L-threonylcarbamoyladenylate synthase
CVS41_RS14420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CVS41_RS14425	COG0512	Glutamine amidotransferase of anthranilate synthase
CVS41_RS14425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CVS41_RS14430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CVS41_RS14435	COG0135	phosphoribosylanthranilate isomerase activity
CVS41_RS14435	COG0134	indole-3-glycerol-phosphate synthase activity
CVS41_RS14440	COG0133	tryptophan synthase activity
CVS41_RS14445	COG0159	tryptophan synthase activity
CVS41_RS14460	COG1988	membrane-bound metal-dependent
CVS41_RS14480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CVS41_RS14490	COG0798	PFAM Bile acid sodium symporter
CVS41_RS14505	COG0640	Transcriptional regulator
CVS41_RS14520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CVS41_RS14530	COG0745	RESPONSE REGULATOR receiver
CVS41_RS14545	COG4988	ABC transporter
CVS41_RS14550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CVS41_RS14570	COG1720	tRNA m6t6A37 methyltransferase activity
CVS41_RS14575	COG3038	cytochrome b561
CVS41_RS14595	COG2862	Uncharacterized protein family, UPF0114
CVS41_RS14610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVS41_RS14615	COG1396	sequence-specific DNA binding
CVS41_RS14615	COG1917	Cupin 2, conserved barrel domain protein
CVS41_RS14630	COG0531	amino acid
CVS41_RS14640	COG0531	amino acid
CVS41_RS14645	COG1283	sodium-dependent phosphate transmembrane transporter activity
CVS41_RS14655	COG0405	Gamma-glutamyltransferase
CVS41_RS14660	COG2974	May be involved in recombination
CVS41_RS14670	COG0420	3'-5' exonuclease activity
CVS41_RS14675	COG0419	ATPase involved in DNA repair
CVS41_RS14690	COG0469	pyruvate kinase activity
CVS41_RS14695	COG1196	nuclear chromosome segregation
CVS41_RS14695	COG3264	Mechanosensitive ion channel
CVS41_RS14705	COG3590	peptidase
CVS41_RS14715	COG2190	(PTS) system
CVS41_RS14725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_RS14730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CVS41_RS14735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVS41_RS14750	COG3437	response regulator, receiver
CVS41_RS14750	COG2770	Histidine kinase
CVS41_RS14755	COG3409	Peptidoglycan-binding domain 1 protein
CVS41_RS14755	COG3267	Type II secretory pathway component ExeA
CVS41_RS14765	COG3031	protein transport across the cell outer membrane
CVS41_RS14775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CVS41_RS14780	COG1459	type II secretion system
CVS41_RS14785	COG2165	general secretion pathway protein
CVS41_RS14795	COG2165	general secretion pathway protein
CVS41_RS14800	COG4795	General secretion pathway protein
CVS41_RS14805	COG3156	type II secretion system protein K
CVS41_RS14815	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CVS41_RS14830	COG0670	Belongs to the BI1 family
CVS41_RS14835	COG1289	transmembrane transporter activity
CVS41_RS14840	COG2920	part of a sulfur-relay system
CVS41_RS14845	COG0673	inositol 2-dehydrogenase activity
CVS41_RS14850	COG0583	DNA-binding transcription factor activity
CVS41_RS14890	COG1032	radical SAM domain protein
CVS41_RS14900	COG1566	PFAM secretion protein HlyD family protein
CVS41_RS14905	COG3706	GGDEF domain
CVS41_RS14910	COG1752	Esterase of the alpha-beta hydrolase superfamily
CVS41_RS14915	COG0531	amino acid
CVS41_RS14950	COG0281	malic enzyme
CVS41_RS14960	COG0534	Mate efflux family protein
CVS41_RS14975	COG2233	PERMEase
CVS41_RS14980	COG0095	Lipoate-protein ligase
CVS41_RS14985	COG1115	amino acid carrier protein
CVS41_RS14990	COG0019	diaminopimelate decarboxylase activity
CVS41_RS15010	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CVS41_RS15025	COG0545	Peptidyl-prolyl cis-trans isomerase
CVS41_RS15030	COG3142	Participates in the control of copper homeostasis
CVS41_RS15055	COG5002	protein histidine kinase activity
CVS41_RS15060	COG0745	RESPONSE REGULATOR receiver
CVS41_RS15065	COG0346	lactoylglutathione lyase activity
CVS41_RS15080	COG0697	spore germination
CVS41_RS15090	COG3290	protein histidine kinase activity
CVS41_RS15095	COG0281	malic enzyme
CVS41_RS15105	COG1846	Transcriptional regulator
CVS41_RS15110	COG1566	PFAM secretion protein HlyD family protein
CVS41_RS15140	COG0602	queuosine metabolic process
CVS41_RS15145	COG1328	CTP reductase activity
CVS41_RS15155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CVS41_RS15160	COG3115	cell septum assembly
CVS41_RS15165	COG1196	nuclear chromosome segregation
CVS41_RS15175	COG2860	membrane
CVS41_RS15185	COG3108	Peptidase M15
CVS41_RS15190	COG2989	Protein conserved in bacteria
CVS41_RS15205	COG0463	Glycosyl transferase, family 2
CVS41_RS15220	COG0366	Alpha amylase catalytic
CVS41_RS15255	COG2199	diguanylate cyclase activity
CVS41_RS15255	COG2203	Gaf domain
CVS41_RS15265	COG3590	peptidase
CVS41_RS15275	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CVS41_RS15280	COG1982	Orn Lys Arg decarboxylase major
CVS41_RS15285	COG0531	amino acid
CVS41_RS15290	COG3710	Transcriptional regulator
CVS41_RS15295	COG0531	amino acid
CVS41_RS15315	COG0814	amino acid
CVS41_RS15345	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CVS41_RS15350	COG0739	heme binding
CVS41_RS15355	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CVS41_RS15365	COG0251	oxidation-reduction process
CVS41_RS15380	COG0583	DNA-binding transcription factor activity
CVS41_RS15385	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_RS15385	COG0604	alcohol dehydrogenase
CVS41_RS15385	COG3321	synthase
CVS41_RS15395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CVS41_RS15405	COG3091	SprT-like family
CVS41_RS15415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CVS41_RS15420	COG0189	ligase activity
CVS41_RS15425	COG1678	Uncharacterized ACR, COG1678
CVS41_RS15430	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CVS41_RS15435	COG3104	oligopeptide transport
CVS41_RS15450	COG0714	Associated with various cellular activities
CVS41_RS15465	COG1115	amino acid carrier protein
CVS41_RS15470	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CVS41_RS15480	COG0825	malonyl-CoA metabolic process
CVS41_RS15490	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CVS41_RS15495	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CVS41_RS15500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CVS41_RS15505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CVS41_RS15510	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CVS41_RS15520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVS41_RS15525	COG0750	zinc metalloprotease
CVS41_RS15530	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CVS41_RS15535	COG0575	Belongs to the CDS family
CVS41_RS15540	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CVS41_RS15545	COG0233	cytoplasmic translational termination
CVS41_RS15550	COG0528	UMP kinase activity
CVS41_RS15555	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CVS41_RS15560	COG0052	Belongs to the universal ribosomal protein uS2 family
CVS41_RS15565	COG0024	Methionine aminopeptidase
CVS41_RS15575	COG2171	N-acyltransferase activity
CVS41_RS15585	COG1263	PTS System
CVS41_RS15585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_RS15595	COG4580	involved in the transport of maltose and maltodextrins
CVS41_RS15605	COG0564	pseudouridine synthase activity
CVS41_RS15610	COG3098	single-species biofilm formation
CVS41_RS15635	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CVS41_RS15645	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CVS41_RS15645	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CVS41_RS15660	COG1611	Belongs to the LOG family
CVS41_RS15665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CVS41_RS15670	COG0473	3-isopropylmalate dehydrogenase activity
CVS41_RS15680	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CVS41_RS15685	COG2363	Small membrane protein
CVS41_RS15695	COG0583	DNA-binding transcription factor activity
CVS41_RS15700	COG0840	transmembrane signaling receptor activity
CVS41_RS15705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CVS41_RS15720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CVS41_RS15725	COG1666	GTP binding
CVS41_RS15730	COG3248	Nucleoside-binding outer membrane protein
CVS41_RS15740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CVS41_RS15750	COG2813	Specifically methylates the guanine in position
CVS41_RS15755	COG0271	Belongs to the BolA IbaG family
CVS41_RS15760	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CVS41_RS15765	COG1805	sodium ion transport
CVS41_RS15770	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CVS41_RS15775	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CVS41_RS15780	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CVS41_RS15785	COG2871	sodium ion transport
CVS41_RS15790	COG1477	protein flavinylation
CVS41_RS15820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CVS41_RS15835	COG0300	oxidoreductase activity
CVS41_RS15845	COG0415	Belongs to the DNA photolyase family
CVS41_RS15850	COG0789	Transcriptional regulator
CVS41_RS15855	COG3272	Protein of unknown function (DUF1722)
CVS41_RS15885	COG1605	Chorismate mutase
CVS41_RS15885	COG0077	Prephenate dehydratase
CVS41_RS15945	COG2801	Transposase and inactivated derivatives
CVS41_RS15950	COG0840	transmembrane signaling receptor activity
CVS41_RS15960	COG4584	PFAM Integrase catalytic
CVS41_RS15965	COG1484	DNA-dependent DNA replication
CVS41_RS15980	COG5377	YqaJ viral recombinase family
CVS41_RS16025	COG2003	Belongs to the UPF0758 family
CVS41_RS16040	COG0469	pyruvate kinase activity
CVS41_RS16050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_RS16050	COG1263	PTS System
CVS41_RS16055	COG1874	Beta-galactosidase
CVS41_RS16060	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CVS41_RS16065	COG3833	ABC-type maltose transport systems, permease component
CVS41_RS16070	COG1175	transmembrane transport
CVS41_RS16075	COG2182	Extracellular solute-binding protein
CVS41_RS16100	COG4580	involved in the transport of maltose and maltodextrins
CVS41_RS16105	COG1609	Transcriptional regulator
CVS41_RS16110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CVS41_RS16115	COG1085	galactose-1-phosphate uridylyltransferase
CVS41_RS16120	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CVS41_RS16160	COG0840	transmembrane signaling receptor activity
CVS41_RS16170	COG0300	oxidoreductase activity
CVS41_RS16195	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CVS41_RS16240	COG0826	peptidase U32
CVS41_RS16245	COG1280	lysine exporter protein (LysE YggA)
CVS41_RS16255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CVS41_RS16265	COG0745	RESPONSE REGULATOR receiver
CVS41_RS16275	COG0643	Histidine kinase
CVS41_RS16275	COG2198	Histidine kinase
CVS41_RS16285	COG0835	chemotaxis
CVS41_RS16290	COG0840	transmembrane signaling receptor activity
CVS41_RS16300	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CVS41_RS16305	COG2201	protein-glutamate methylesterase activity
CVS41_RS16310	COG1185	polyribonucleotide nucleotidyltransferase activity
CVS41_RS16315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CVS41_RS16320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CVS41_RS16325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CVS41_RS16330	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CVS41_RS16335	COG0195	Participates in both transcription termination and antitermination
CVS41_RS16340	COG0779	Required for maturation of 30S ribosomal subunits
CVS41_RS16355	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CVS41_RS16360	COG0149	triose-phosphate isomerase activity
CVS41_RS16365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CVS41_RS16370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CVS41_RS16380	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CVS41_RS16385	COG1534	Rna-binding protein
CVS41_RS16400	COG1360	Flagellar Motor Protein
CVS41_RS16405	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CVS41_RS16410	COG1722	exodeoxyribonuclease VII activity
CVS41_RS16415	COG0142	geranyltranstransferase activity
CVS41_RS16420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CVS41_RS16425	COG0737	Belongs to the 5'-nucleotidase family
CVS41_RS16445	COG2204	response regulator
CVS41_RS16450	COG0545	Peptidyl-prolyl cis-trans isomerase
CVS41_RS16460	COG2900	Belongs to the SlyX family
CVS41_RS16470	COG0601	transmembrane transport
CVS41_RS16490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CVS41_RS16495	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CVS41_RS16500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CVS41_RS16505	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CVS41_RS16520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CVS41_RS16520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CVS41_RS16525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CVS41_RS16535	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CVS41_RS16545	COG2198	Histidine kinase
CVS41_RS16545	COG0784	Response regulator, receiver
CVS41_RS16545	COG2205	protein histidine kinase activity
CVS41_RS16550	COG1879	ABC-type sugar transport system periplasmic component
CVS41_RS16560	COG0745	RESPONSE REGULATOR receiver
CVS41_RS16565	COG3005	denitrification pathway
CVS41_RS16575	COG3381	protein complex oligomerization
CVS41_RS16595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CVS41_RS16600	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CVS41_RS16605	COG0511	ligase activity, forming carbon-carbon bonds
CVS41_RS16610	COG0439	Biotin carboxylase
CVS41_RS16620	COG4145	pantothenate transmembrane transporter activity
CVS41_RS16625	COG2190	(PTS) system
CVS41_RS16625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_RS16625	COG1263	PTS System
CVS41_RS16630	COG0583	DNA-binding transcription factor activity
CVS41_RS16635	COG0604	alcohol dehydrogenase
CVS41_RS16640	COG2264	protein methyltransferase activity
CVS41_RS16645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CVS41_RS16655	COG0778	Nitroreductase
CVS41_RS16660	COG1902	pentaerythritol trinitrate reductase activity
CVS41_RS16660	COG0446	pyridine nucleotide-disulphide oxidoreductase
CVS41_RS16665	COG0616	signal peptide processing
CVS41_RS16685	COG0848	biopolymer transport protein
CVS41_RS16690	COG0811	peptide transport
CVS41_RS16695	COG0811	peptide transport
CVS41_RS16710	COG4174	ABC transporter (Permease)
CVS41_RS16715	COG4239	(ABC) transporter, permease
CVS41_RS16725	COG0444	Belongs to the ABC transporter superfamily
CVS41_RS16730	COG4608	Belongs to the ABC transporter superfamily
CVS41_RS16750	COG3416	Protein conserved in bacteria
CVS41_RS16760	COG0741	lytic transglycosylase activity
CVS41_RS16775	COG0488	(ABC) transporter
CVS41_RS16785	COG2252	PERMEase
CVS41_RS16790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CVS41_RS16795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CVS41_RS16800	COG0840	transmembrane signaling receptor activity
CVS41_RS16810	COG1278	Cold shock
CVS41_RS16850	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CVS41_RS16855	COG1162	GTPase activity
CVS41_RS16860	COG0688	phosphatidylethanolamine metabolic process
CVS41_RS16865	COG4628	conserved protein (DUF2132)
CVS41_RS16880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CVS41_RS16895	COG1073	alpha beta
CVS41_RS16900	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CVS41_RS16910	COG2195	Cleaves the N-terminal amino acid of tripeptides
CVS41_RS16915	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CVS41_RS16920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CVS41_RS16925	COG3178	'Phosphotransferase
CVS41_RS16930	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CVS41_RS16935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CVS41_RS16940	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CVS41_RS16945	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CVS41_RS16950	COG2967	ApaG domain
CVS41_RS16955	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CVS41_RS16970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVS41_RS16980	COG3314	Sporulation integral membrane protein YlbJ
CVS41_RS16985	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CVS41_RS16990	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CVS41_RS16995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CVS41_RS17000	COG0142	geranyltranstransferase activity
CVS41_RS17005	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CVS41_RS17010	COG0330	HflC and HflK could
CVS41_RS17015	COG0330	HflC and HflK could
CVS41_RS17020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CVS41_RS17025	COG1923	regulation of RNA biosynthetic process
CVS41_RS17030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CVS41_RS17035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CVS41_RS17040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CVS41_RS17050	COG0802	atpase or kinase
CVS41_RS17055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CVS41_RS17055	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CVS41_RS17075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CVS41_RS17080	COG2011	ABC-type metal ion transport system permease component
CVS41_RS17085	COG1464	Belongs to the NlpA lipoprotein family
CVS41_RS17120	COG0784	Response regulator, receiver
CVS41_RS17120	COG2198	Histidine kinase
CVS41_RS17120	COG5002	protein histidine kinase activity
CVS41_RS17155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CVS41_RS17160	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CVS41_RS17165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CVS41_RS17170	COG2716	regulation of RNA biosynthetic process
CVS41_RS17175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CVS41_RS17180	COG3013	Belongs to the UPF0304 family
CVS41_RS17190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CVS41_RS17195	COG0280	phosphate acetyltransferase
CVS41_RS17195	COG0857	belongs to the CobB CobQ family
CVS41_RS17200	COG1555	photosystem II stabilization
CVS41_RS17205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CVS41_RS17210	COG3104	oligopeptide transport
CVS41_RS17215	COG0745	RESPONSE REGULATOR receiver
CVS41_RS17245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_RS17260	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CVS41_RS17295	COG0440	acetolactate synthase activity
CVS41_RS17300	COG0028	Belongs to the TPP enzyme family
CVS41_RS17325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CVS41_RS17330	COG0473	3-isopropylmalate dehydrogenase activity
CVS41_RS17335	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CVS41_RS17340	COG0066	3-isopropylmalate dehydratase activity
CVS41_RS17355	COG4143	(ABC) transporter
CVS41_RS17360	COG1178	ABC-type Fe3 transport system permease component
CVS41_RS17365	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CVS41_RS17370	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CVS41_RS17420	COG0459	protein refolding
CVS41_RS17425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CVS41_RS17430	COG0534	Mate efflux family protein
CVS41_RS17435	COG3030	protein affecting phage T7 exclusion by the F plasmid
CVS41_RS17440	COG1027	Aspartate ammonia-lyase
CVS41_RS17445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CVS41_RS17450	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CVS41_RS17455	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CVS41_RS17460	COG1610	YqeY-like protein
CVS41_RS17465	COG0358	DNA primase activity
CVS41_RS17470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CVS41_RS17515	COG1609	Transcriptional regulator
CVS41_RS17525	COG0840	transmembrane signaling receptor activity
CVS41_RS17530	COG1472	Belongs to the glycosyl hydrolase 3 family
CVS41_RS17535	COG5297	Belongs to the glycosyl hydrolase family 6
CVS41_RS17535	COG2273	Hydrolase Family 16
CVS41_RS17540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CVS41_RS17545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CVS41_RS17545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CVS41_RS17550	COG2723	6-phospho-beta-galactosidase activity
CVS41_RS17555	COG1447	Phosphotransferase system cellobiose-specific component IIA
CVS41_RS17590	COG0305	Participates in initiation and elongation during chromosome replication
CVS41_RS17620	COG0151	Belongs to the GarS family
CVS41_RS17625	COG0138	bifunctional purine biosynthesis protein purh
CVS41_RS17635	COG3036	rescue of stalled ribosome
CVS41_RS17640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CVS41_RS17645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CVS41_RS17655	COG0673	inositol 2-dehydrogenase activity
CVS41_RS17665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CVS41_RS17670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CVS41_RS17680	COG0583	DNA-binding transcription factor activity
CVS41_RS17685	COG0477	Major facilitator Superfamily
CVS41_RS17700	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_RS17725	COG0456	acetyltransferase
CVS41_RS17735	COG1022	Amp-dependent synthetase and ligase
CVS41_RS17740	COG2918	glutathione biosynthetic process
CVS41_RS17745	COG0612	Peptidase, M16
CVS41_RS17750	COG1238	metal cluster binding
CVS41_RS17780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVS41_RS17785	COG0359	binds to the 23S rRNA
CVS41_RS17790	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CVS41_RS17795	COG0360	Binds together with S18 to 16S ribosomal RNA
CVS41_RS17800	COG1914	H( )-stimulated, divalent metal cation uptake system
CVS41_RS17805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CVS41_RS17815	COG0776	regulation of translation
CVS41_RS17830	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CVS41_RS17845	COG0560	Phosphoserine phosphatase
CVS41_RS17855	COG0813	purine-nucleoside phosphorylase activity
CVS41_RS17860	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CVS41_RS17865	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CVS41_RS17870	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CVS41_RS17880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CVS41_RS17885	COG0084	hydrolase, TatD family'
CVS41_RS17890	COG2165	general secretion pathway protein
CVS41_RS17900	COG1854	S-ribosylhomocysteine lyase activity
CVS41_RS17915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CVS41_RS17915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CVS41_RS17975	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CVS41_RS17980	COG1047	Peptidyl-prolyl cis-trans
CVS41_RS17985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CVS41_RS17990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CVS41_RS17995	COG0196	riboflavin kinase activity
CVS41_RS18000	COG0728	peptidoglycan biosynthetic process
CVS41_RS18005	COG0268	Binds directly to 16S ribosomal RNA
CVS41_RS18010	COG0640	Transcriptional regulator
CVS41_RS18015	COG0583	DNA-binding transcription factor activity
CVS41_RS18025	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CVS41_RS18030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CVS41_RS18035	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CVS41_RS18045	COG1051	belongs to the nudix hydrolase family
CVS41_RS18050	COG3066	DNA modification
CVS41_RS18060	COG0335	large ribosomal subunit rRNA binding
CVS41_RS18065	COG0336	Belongs to the RNA methyltransferase TrmD family
CVS41_RS18070	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CVS41_RS18075	COG0228	four-way junction DNA binding
CVS41_RS18080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CVS41_RS18085	COG4137	Cytochrome C assembly protein
CVS41_RS18090	COG4536	flavin adenine dinucleotide binding
CVS41_RS18100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVS41_RS18100	COG1017	nitric oxide dioxygenase activity
CVS41_RS18105	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CVS41_RS18110	COG0039	L-malate dehydrogenase activity
CVS41_RS18115	COG4160	amino acid transport
CVS41_RS18120	COG4215	(ABC) transporter
CVS41_RS18125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_RS18130	COG1126	abc transporter atp-binding protein
CVS41_RS18135	COG1438	arginine binding
CVS41_RS18140	COG2837	iron assimilation
CVS41_RS18145	COG3842	ATPase activity
CVS41_RS18155	COG1840	ABC-type Fe3 transport system, periplasmic component
CVS41_RS18160	COG0347	Belongs to the P(II) protein family
CVS41_RS18180	COG3022	response to hydroperoxide
CVS41_RS18195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CVS41_RS18200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CVS41_RS18205	COG0762	integral membrane protein
CVS41_RS18210	COG1872	DUF167
CVS41_RS18220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CVS41_RS18225	COG0583	DNA-binding transcription factor activity
CVS41_RS18240	COG1929	Belongs to the glycerate kinase type-1 family
CVS41_RS18245	COG2610	gluconate transmembrane transporter activity
CVS41_RS18250	COG3835	regulator
CVS41_RS18255	COG3112	Uncharacterised protein family (UPF0231)
CVS41_RS18275	COG0513	Belongs to the DEAD box helicase family
CVS41_RS18315	COG0457	Tetratricopeptide repeat
CVS41_RS18315	COG3118	belongs to the thioredoxin family
CVS41_RS18325	COG1215	transferase activity, transferring glycosyl groups
CVS41_RS18330	COG1215	transferase activity, transferring glycosyl groups
CVS41_RS18345	COG2194	sulfuric ester hydrolase activity
CVS41_RS18350	COG1448	Aminotransferase
CVS41_RS18365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CVS41_RS18370	COG1328	CTP reductase activity
CVS41_RS18395	COG0543	2 iron, 2 sulfur cluster binding
CVS41_RS18395	COG0633	Ferredoxin
CVS41_RS18410	COG1215	transferase activity, transferring glycosyl groups
CVS41_RS18415	COG0726	polysaccharide deacetylase
CVS41_RS18415	COG1649	PFAM Uncharacterised BCR, COG1649
CVS41_RS18430	COG0840	transmembrane signaling receptor activity
CVS41_RS18435	COG3397	chitin binding
CVS41_RS18440	COG3174	membrane
CVS41_RS18445	COG0110	maltose O-acetyltransferase activity
CVS41_RS18460	COG1011	Hydrolase
CVS41_RS18465	COG0494	nUDIX hydrolase
CVS41_RS18470	COG1218	3'(2'),5'-bisphosphate nucleotidase
CVS41_RS18475	COG0814	amino acid
CVS41_RS18480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVS41_RS18495	COG0626	cystathionine gamma-synthase activity
CVS41_RS18500	COG0527	aspartate kinase activity
CVS41_RS18500	COG0460	homoserine dehydrogenase
CVS41_RS18505	COG0306	phosphate transporter
CVS41_RS18510	COG1392	Phosphate transport regulator
CVS41_RS18520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CVS41_RS18525	COG2813	Specifically methylates the guanine in position
CVS41_RS18530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CVS41_RS18535	COG0297	glycogen (starch) synthase activity
CVS41_RS18575	COG1757	Na H antiporter
CVS41_RS18580	COG0316	Belongs to the HesB IscA family
CVS41_RS18590	COG0038	chloride channel
CVS41_RS18595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CVS41_RS18610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CVS41_RS18610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CVS41_RS18640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CVS41_RS18645	COG0564	pseudouridine synthase activity
CVS41_RS18655	COG0110	maltose O-acetyltransferase activity
CVS41_RS18660	COG0366	Alpha amylase catalytic
CVS41_RS18665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_RS18665	COG1263	PTS System
CVS41_RS18670	COG1609	Transcriptional regulator
CVS41_RS18685	COG0252	asparaginase activity
CVS41_RS18690	COG1253	flavin adenine dinucleotide binding
CVS41_RS18695	COG0586	Pfam SNARE associated Golgi protein
CVS41_RS18700	COG1686	Belongs to the peptidase S11 family
CVS41_RS18735	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CVS41_RS18740	COG0527	aspartate kinase activity
CVS41_RS18745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CVS41_RS18755	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CVS41_RS18775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVS41_RS18825	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CVS41_RS18850	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CVS41_RS18855	COG4667	esterase of the alpha-beta hydrolase superfamily
CVS41_RS18865	COG1346	cytolysis
CVS41_RS18870	COG1380	Effector of murein hydrolase LrgA
CVS41_RS18875	COG0583	DNA-binding transcription factor activity
CVS41_RS18890	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CVS41_RS18910	COG2131	deaminase
CVS41_RS18915	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CVS41_RS18920	COG2022	thiamine diphosphate biosynthetic process
CVS41_RS18930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CVS41_RS18935	COG0352	thiamine-phosphate diphosphorylase activity
CVS41_RS18940	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CVS41_RS18960	COG0745	RESPONSE REGULATOR receiver
CVS41_RS18965	COG0642	Histidine kinase
CVS41_RS18970	COG0189	ligase activity
CVS41_RS19015	COG0477	Major facilitator Superfamily
CVS41_RS19030	COG0312	modulator of DNA gyrase
CVS41_RS19035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CVS41_RS19050	COG3164	Protein of unknown function
CVS41_RS19055	COG1530	ribonuclease E activity
CVS41_RS19060	COG0424	maF-like protein
CVS41_RS19065	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CVS41_RS19070	COG1792	Involved in formation and maintenance of cell shape
CVS41_RS19075	COG1077	Cell shape determining protein MreB Mrl
CVS41_RS19105	COG2165	general secretion pathway protein
CVS41_RS19120	COG1459	type II secretion system
CVS41_RS19125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CVS41_RS19170	COG2199	diguanylate cyclase activity
CVS41_RS19170	COG2200	EAL domain
CVS41_RS19175	COG2200	EAL domain
CVS41_RS19180	COG0387	Pfam Sodium calcium exchanger
CVS41_RS19185	COG2986	histidine ammonia-lyase
CVS41_RS19190	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CVS41_RS19195	COG0010	Belongs to the arginase family
CVS41_RS19200	COG1228	amidohydrolase
CVS41_RS19205	COG2188	Transcriptional regulator
CVS41_RS19210	COG0288	reversible hydration of carbon dioxide
CVS41_RS19220	COG2177	Part of the ABC transporter FtsEX involved in
CVS41_RS19225	COG2884	Cell division ATP-binding protein ftsE
CVS41_RS19230	COG0552	protein localization to endoplasmic reticulum
CVS41_RS19235	COG0742	ribosomal rna small subunit methyltransferase
CVS41_RS19260	COG2249	NAD(P)H dehydrogenase (quinone) activity
CVS41_RS19265	COG0583	DNA-binding transcription factor activity
CVS41_RS19270	COG4221	oxidoreductase activity
CVS41_RS19285	COG1770	oligopeptidase
CVS41_RS19300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CVS41_RS19305	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CVS41_RS19315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CVS41_RS19325	COG2095	MarC family integral membrane protein
CVS41_RS19335	COG1301	dicarboxylic acid transport
CVS41_RS19360	COG3714	YhhN family
CVS41_RS19415	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CVS41_RS19420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CVS41_RS19425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CVS41_RS19430	COG0049	tRNA binding
CVS41_RS19435	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CVS41_RS19440	COG2168	tRNA wobble position uridine thiolation
CVS41_RS19445	COG2923	Belongs to the DsrF TusC family
CVS41_RS19450	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CVS41_RS19460	COG2964	Protein conserved in bacteria
CVS41_RS19465	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CVS41_RS19470	COG0085	RNA polymerase activity
CVS41_RS19475	COG0222	ribosome binding
CVS41_RS19480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CVS41_RS19485	COG0081	regulation of translation
CVS41_RS19490	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CVS41_RS19495	COG0250	Participates in transcription elongation, termination and antitermination