locus-tag	class	description
OCAR_RS00015	COG0741	lytic transglycosylase activity
OCAR_RS00070	COG5489	Protein of unknown function (DUF736)
OCAR_RS00075	COG0793	Belongs to the peptidase S41A family
OCAR_RS00095	COG0789	Transcriptional regulator
OCAR_RS00105	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCAR_RS00125	COG0431	NADPH-dependent FMN reductase
OCAR_RS00130	COG0798	PFAM Bile acid sodium symporter
OCAR_RS00145	COG0640	Transcriptional regulator
OCAR_RS00195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCAR_RS00200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCAR_RS00210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCAR_RS00225	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OCAR_RS00230	COG0069	glutamate synthase activity
OCAR_RS00305	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OCAR_RS00355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OCAR_RS00360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OCAR_RS00370	COG4974	Belongs to the 'phage' integrase family
OCAR_RS00375	COG0825	malonyl-CoA metabolic process
OCAR_RS00380	COG3034	peptidoglycan biosynthetic process
OCAR_RS00390	COG0653	protein targeting
OCAR_RS00395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCAR_RS00400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OCAR_RS00405	COG0494	nUDIX hydrolase
OCAR_RS00410	COG2226	methyltransferase
OCAR_RS00415	COG1040	competence protein
OCAR_RS00420	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OCAR_RS00425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OCAR_RS00440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCAR_RS00450	COG0527	aspartate kinase activity
OCAR_RS00460	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
OCAR_RS00465	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OCAR_RS00470	COG2890	protein-(glutamine-N5) methyltransferase activity
OCAR_RS00485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCAR_RS00495	COG0154	amidase activity
OCAR_RS00515	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
OCAR_RS00525	COG3300	MHYT domain
OCAR_RS00525	COG5001	Diguanylate cyclase
OCAR_RS00540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OCAR_RS00545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OCAR_RS00550	COG0142	geranyltranstransferase activity
OCAR_RS00565	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OCAR_RS00570	COG0735	belongs to the Fur family
OCAR_RS00580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OCAR_RS00600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCAR_RS00605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCAR_RS00610	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OCAR_RS00615	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OCAR_RS00635	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
OCAR_RS00655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCAR_RS00660	COG1902	pentaerythritol trinitrate reductase activity
OCAR_RS00715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OCAR_RS00755	COG0210	DNA helicase
OCAR_RS00775	COG3093	addiction module antidote protein HigA
OCAR_RS00780	COG0071	Belongs to the small heat shock protein (HSP20) family
OCAR_RS00785	COG0071	Belongs to the small heat shock protein (HSP20) family
OCAR_RS00840	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OCAR_RS00845	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OCAR_RS00850	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
OCAR_RS00855	COG2205	protein histidine kinase activity
OCAR_RS00865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCAR_RS00875	COG0583	DNA-binding transcription factor activity
OCAR_RS00880	COG2948	multi-organism process
OCAR_RS00895	COG3846	protein secretion by the type IV secretion system
OCAR_RS00910	COG3451	type IV secretory pathway VirB4
OCAR_RS00925	COG4962	Type ii secretion system protein e
OCAR_RS00945	COG0741	lytic transglycosylase activity
OCAR_RS00970	COG1192	Involved in chromosome partitioning
OCAR_RS01000	COG5489	Protein of unknown function (DUF736)
OCAR_RS01095	COG0431	NADPH-dependent FMN reductase
OCAR_RS01100	COG0798	PFAM Bile acid sodium symporter
OCAR_RS01120	COG4974	Belongs to the 'phage' integrase family
OCAR_RS01130	COG3453	Protein conserved in bacteria
OCAR_RS01130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCAR_RS01145	COG2151	metal-sulfur cluster biosynthetic enzyme
OCAR_RS01200	COG3794	PFAM blue (type 1) copper domain protein
OCAR_RS01220	COG1595	DNA-templated transcription, initiation
OCAR_RS01225	COG4191	Histidine kinase
OCAR_RS01235	COG2917	probably involved in intracellular septation
OCAR_RS01240	COG0552	protein localization to endoplasmic reticulum
OCAR_RS01245	COG0564	pseudouridine synthase activity
OCAR_RS01250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OCAR_RS01255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OCAR_RS01270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OCAR_RS01275	COG0228	four-way junction DNA binding
OCAR_RS01280	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OCAR_RS01285	COG0336	Belongs to the RNA methyltransferase TrmD family
OCAR_RS01290	COG0335	large ribosomal subunit rRNA binding
OCAR_RS01300	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OCAR_RS01315	COG0066	3-isopropylmalate dehydratase activity
OCAR_RS01320	COG2301	Belongs to the HpcH HpaI aldolase family
OCAR_RS01325	COG0288	reversible hydration of carbon dioxide
OCAR_RS01330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OCAR_RS01340	COG0473	3-isopropylmalate dehydrogenase activity
OCAR_RS01345	COG0477	Major facilitator Superfamily
OCAR_RS01350	COG0318	PFAM AMP-dependent synthetase and ligase
OCAR_RS01355	COG0730	response to heat
OCAR_RS01395	COG0137	argininosuccinate synthase activity
OCAR_RS01400	COG0671	phosphoesterase, PA-phosphatase related
OCAR_RS01410	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OCAR_RS01425	COG2154	pterin-4-alpha-carbinolamine dehydratase
OCAR_RS01435	COG1217	gtp-binding protein TYPA
OCAR_RS01445	COG1247	-acetyltransferase
OCAR_RS01450	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OCAR_RS01455	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OCAR_RS01460	COG1872	DUF167
OCAR_RS01480	COG4221	oxidoreductase activity
OCAR_RS01505	COG0583	DNA-binding transcription factor activity
OCAR_RS01535	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OCAR_RS01540	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OCAR_RS01550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OCAR_RS01555	COG1376	ErfK ybiS ycfS ynhG family protein
OCAR_RS01580	COG0138	bifunctional purine biosynthesis protein purh
OCAR_RS01590	COG0405	Gamma-glutamyltransferase
OCAR_RS01605	COG0432	Pfam Uncharacterised protein family UPF0047
OCAR_RS01620	COG3118	belongs to the thioredoxin family
OCAR_RS01630	COG2835	tetraacyldisaccharide 4'-kinase activity
OCAR_RS01635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCAR_RS01640	COG1946	Acyl-CoA thioesterase
OCAR_RS01645	COG0347	Belongs to the P(II) protein family
OCAR_RS01650	COG0004	ammonium transporteR
OCAR_RS01655	COG0436	Aminotransferase
OCAR_RS01660	COG1674	ftsk spoiiie
OCAR_RS01675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCAR_RS01680	COG0745	RESPONSE REGULATOR receiver
OCAR_RS01690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OCAR_RS01695	COG2203	Gaf domain
OCAR_RS01695	COG3706	GGDEF domain
OCAR_RS01695	COG4251	negative regulation of phosphorylation
OCAR_RS01695	COG5001	Diguanylate cyclase
OCAR_RS01700	COG0495	leucyl-tRNA aminoacylation
OCAR_RS01730	COG0357	Ribosomal RNA small subunit methyltransferase G
OCAR_RS01735	COG0445	tRNA wobble uridine modification
OCAR_RS01740	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OCAR_RS01745	COG1331	Highly conserved protein containing a thioredoxin domain
OCAR_RS01750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCAR_RS01755	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OCAR_RS01775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCAR_RS01785	COG1396	sequence-specific DNA binding
OCAR_RS01790	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OCAR_RS01795	COG1981	membrane
OCAR_RS01800	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OCAR_RS01805	COG0424	maF-like protein
OCAR_RS01810	COG0237	dephospho-CoA kinase activity
OCAR_RS01815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OCAR_RS01820	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OCAR_RS01830	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
OCAR_RS01840	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OCAR_RS01845	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OCAR_RS01850	COG0131	Imidazoleglycerol-phosphate dehydratase
OCAR_RS01860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OCAR_RS01865	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OCAR_RS01870	COG0107	imidazoleglycerol-phosphate synthase activity
OCAR_RS01875	COG0140	phosphoribosyl-ATP diphosphatase activity
OCAR_RS01880	COG1072	(Pantothenic acid kinase))
OCAR_RS01910	COG0189	ligase activity
OCAR_RS01915	COG0792	nuclease activity
OCAR_RS01920	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OCAR_RS01930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OCAR_RS01935	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OCAR_RS01940	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OCAR_RS01945	COG1420	regulation of RNA biosynthetic process
OCAR_RS01950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OCAR_RS01960	COG0443	Heat shock 70 kDa protein
OCAR_RS01970	COG3963	phosphatidate phosphatase activity
OCAR_RS01980	COG0284	orotidine-5'-phosphate decarboxylase activity
OCAR_RS01985	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OCAR_RS01990	COG0588	phosphoglycerate mutase activity
OCAR_RS02005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OCAR_RS02025	COG2267	carboxylic ester hydrolase activity
OCAR_RS02035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCAR_RS02045	COG0747	negative chemotaxis
OCAR_RS02050	COG0583	DNA-binding transcription factor activity
OCAR_RS02065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCAR_RS02065	COG0072	phenylalanine-tRNA ligase activity
OCAR_RS02070	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OCAR_RS02075	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OCAR_RS02080	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OCAR_RS02085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OCAR_RS02105	COG1968	undecaprenyl-diphosphatase activity
OCAR_RS02120	COG5001	Diguanylate cyclase
OCAR_RS02120	COG5002	protein histidine kinase activity
OCAR_RS02120	COG3447	MASE1 domain protein
OCAR_RS02135	COG0058	SHG alpha-glucan phosphorylase activity
OCAR_RS02140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCAR_RS02150	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OCAR_RS02155	COG1137	ATPase activity
OCAR_RS02160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OCAR_RS02165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OCAR_RS02170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCAR_RS02175	COG0129	dihydroxy-acid dehydratase activity
OCAR_RS02185	COG0071	Belongs to the small heat shock protein (HSP20) family
OCAR_RS02200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OCAR_RS02215	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OCAR_RS02225	COG0539	negative regulation of cytoplasmic translation
OCAR_RS02230	COG0616	signal peptide processing
OCAR_RS02235	COG0776	regulation of translation
OCAR_RS02245	COG0135	phosphoribosylanthranilate isomerase activity
OCAR_RS02250	COG0133	tryptophan synthase activity
OCAR_RS02255	COG0159	tryptophan synthase activity
OCAR_RS02260	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OCAR_RS02275	COG1074	ATP-dependent DNA helicase activity
OCAR_RS02285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OCAR_RS02295	COG3178	'Phosphotransferase
OCAR_RS02300	COG2205	protein histidine kinase activity
OCAR_RS02305	COG0756	dUTP diphosphatase activity
OCAR_RS02310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OCAR_RS02315	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OCAR_RS02320	COG2226	methyltransferase
OCAR_RS02325	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OCAR_RS02330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OCAR_RS02350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OCAR_RS02360	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCAR_RS02370	COG0583	DNA-binding transcription factor activity
OCAR_RS02380	COG1185	polyribonucleotide nucleotidyltransferase activity
OCAR_RS02385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OCAR_RS02390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OCAR_RS02395	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OCAR_RS02415	COG0779	Required for maturation of 30S ribosomal subunits
OCAR_RS02425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OCAR_RS02430	COG1396	sequence-specific DNA binding
OCAR_RS02435	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OCAR_RS02440	COG1253	flavin adenine dinucleotide binding
OCAR_RS02445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OCAR_RS02450	COG1702	phosphate starvation-inducible protein PhoH
OCAR_RS02455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OCAR_RS02465	COG0456	acetyltransferase
OCAR_RS02470	COG1214	PFAM Peptidase M22, glycoprotease
OCAR_RS02475	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OCAR_RS02480	COG0180	Tryptophanyl-tRNA synthetase
OCAR_RS02485	COG0728	peptidoglycan biosynthetic process
OCAR_RS02490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCAR_RS02505	COG1741	Belongs to the pirin family
OCAR_RS02515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OCAR_RS02520	COG2852	Protein conserved in bacteria
OCAR_RS02530	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OCAR_RS02535	COG0268	Binds directly to 16S ribosomal RNA
OCAR_RS02545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCAR_RS02560	COG0784	Response regulator, receiver
OCAR_RS02560	COG4191	Histidine kinase
OCAR_RS02565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OCAR_RS02570	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCAR_RS02590	COG1091	dTDP-4-dehydrorhamnose reductase activity
OCAR_RS02605	COG1132	(ABC) transporter
OCAR_RS02615	COG1215	transferase activity, transferring glycosyl groups
OCAR_RS02630	COG1120	ATPase activity
OCAR_RS02645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OCAR_RS02655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCAR_RS02665	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCAR_RS02670	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCAR_RS02675	COG4133	protoheme IX ABC transporter activity
OCAR_RS02680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OCAR_RS02700	COG0670	Belongs to the BI1 family
OCAR_RS02710	COG4181	ATPase activity
OCAR_RS02720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OCAR_RS02725	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OCAR_RS02730	COG0039	L-malate dehydrogenase activity
OCAR_RS02740	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCAR_RS02745	COG1028	Short-chain dehydrogenase reductase Sdr
OCAR_RS02750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCAR_RS02760	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OCAR_RS02770	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OCAR_RS02775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OCAR_RS02780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OCAR_RS02785	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OCAR_RS02790	COG1764	response to oxidative stress
OCAR_RS02795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OCAR_RS02800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OCAR_RS02805	COG0494	nUDIX hydrolase
OCAR_RS02820	COG0793	Belongs to the peptidase S41A family
OCAR_RS02830	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OCAR_RS02835	COG0799	negative regulation of ribosome biogenesis
OCAR_RS02840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OCAR_RS02845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OCAR_RS02850	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OCAR_RS02855	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OCAR_RS02860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCAR_RS02865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OCAR_RS02870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OCAR_RS02880	COG0477	Major facilitator Superfamily
OCAR_RS02885	COG1877	trehalose-phosphatase activity
OCAR_RS02890	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OCAR_RS02905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OCAR_RS02930	COG4585	Histidine kinase
OCAR_RS02935	COG2197	response regulator
OCAR_RS02940	COG0405	Gamma-glutamyltransferase
OCAR_RS02945	COG0402	S-adenosylhomocysteine deaminase activity
OCAR_RS02965	COG4948	Mandelate Racemase Muconate Lactonizing
OCAR_RS02980	COG2514	catechol 2,3-dioxygenase activity
OCAR_RS02985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCAR_RS02990	COG1376	ErfK ybiS ycfS ynhG family protein
OCAR_RS02995	COG1294	oxidase, subunit
OCAR_RS03000	COG1271	oxidase subunit
OCAR_RS03025	COG5002	protein histidine kinase activity
OCAR_RS03030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OCAR_RS03035	COG0573	inorganic phosphate transmembrane transporter activity
OCAR_RS03040	COG0581	inorganic phosphate transmembrane transporter activity
OCAR_RS03045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OCAR_RS03050	COG0704	Plays a role in the regulation of phosphate uptake
OCAR_RS03055	COG0745	RESPONSE REGULATOR receiver
OCAR_RS03065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OCAR_RS03070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OCAR_RS03080	COG2967	ApaG domain
OCAR_RS03105	COG0717	Belongs to the dCTP deaminase family
OCAR_RS03120	COG1999	signal sequence binding
OCAR_RS03130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCAR_RS03135	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
OCAR_RS03160	COG0167	dihydroorotate dehydrogenase activity
OCAR_RS03165	COG0534	Mate efflux family protein
OCAR_RS03185	COG1846	Transcriptional regulator
OCAR_RS03205	COG0312	modulator of DNA gyrase
OCAR_RS03215	COG1565	acr, cog1565
OCAR_RS03215	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OCAR_RS03220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OCAR_RS03225	COG0109	protoheme IX farnesyltransferase activity
OCAR_RS03235	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OCAR_RS03245	COG3346	SURF1 family
OCAR_RS03255	COG0612	Peptidase, M16
OCAR_RS03270	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OCAR_RS03275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OCAR_RS03285	COG0356	it plays a direct role in the translocation of protons across the membrane
OCAR_RS03305	COG0784	Response regulator, receiver
OCAR_RS03305	COG2205	protein histidine kinase activity
OCAR_RS03310	COG4566	intracellular signal transduction
OCAR_RS03315	COG0156	8-amino-7-oxononanoate synthase activity
OCAR_RS03320	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OCAR_RS03330	COG0235	Class ii aldolase
OCAR_RS03365	COG1764	response to oxidative stress
OCAR_RS03370	COG0697	spore germination
OCAR_RS03380	COG1309	transcriptional regulator
OCAR_RS03390	COG4774	siderophore transport
OCAR_RS03430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OCAR_RS03440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OCAR_RS03445	COG5328	Belongs to the UPF0262 family
OCAR_RS03450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OCAR_RS03455	COG0424	maF-like protein
OCAR_RS03465	COG5001	Diguanylate cyclase
OCAR_RS03480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCAR_RS03510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OCAR_RS03525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCAR_RS03545	COG2096	Adenosyltransferase
OCAR_RS03550	COG2086	electron transfer activity
OCAR_RS03555	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OCAR_RS03560	COG1250	3-hydroxyacyl-CoA dehydrogenase
OCAR_RS03570	COG2764	glyoxalase bleomycin resistance protein dioxygenase
OCAR_RS03575	COG5507	3-demethylubiquinone-9 3-methyltransferase
OCAR_RS03580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCAR_RS03585	COG0165	Argininosuccinate lyase
OCAR_RS03595	COG0019	diaminopimelate decarboxylase activity
OCAR_RS03615	COG2884	Cell division ATP-binding protein ftsE
OCAR_RS03645	COG0287	Prephenate dehydrogenase
OCAR_RS03650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OCAR_RS03660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OCAR_RS03665	COG2813	Specifically methylates the guanine in position
OCAR_RS03665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OCAR_RS03680	COG0542	response to heat
OCAR_RS03685	COG0739	heme binding
OCAR_RS03875	COG1475	DNA binding
OCAR_RS04025	COG1309	transcriptional regulator
OCAR_RS04030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCAR_RS04040	COG0577	efflux transmembrane transporter activity
OCAR_RS04040	COG1136	(ABC) transporter
OCAR_RS04050	COG0842	Transport permease protein
OCAR_RS04055	COG0842	Transport permease protein
OCAR_RS04060	COG1131	(ABC) transporter
OCAR_RS04070	COG1309	transcriptional regulator
OCAR_RS04085	COG1028	Short-chain dehydrogenase reductase Sdr
OCAR_RS04095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OCAR_RS04100	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCAR_RS04145	COG3038	cytochrome b561
OCAR_RS04160	COG1477	protein flavinylation
OCAR_RS04175	COG2217	Heavy metal translocating P-type atpase
OCAR_RS04180	COG2217	Heavy metal translocating P-type atpase
OCAR_RS04190	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OCAR_RS04195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCAR_RS04200	COG4558	Periplasmic binding protein
OCAR_RS04260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OCAR_RS04265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OCAR_RS04290	COG0523	cobalamin synthesis protein
OCAR_RS04320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OCAR_RS04355	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
OCAR_RS04360	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OCAR_RS04365	COG0330	HflC and HflK could
OCAR_RS04390	COG4251	negative regulation of phosphorylation
OCAR_RS04390	COG5001	Diguanylate cyclase
OCAR_RS04390	COG2203	Gaf domain
OCAR_RS04390	COG3706	GGDEF domain
OCAR_RS04410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OCAR_RS04415	COG2951	lytic endotransglycosylase activity
OCAR_RS04435	COG0067	glutamate synthase
OCAR_RS04435	COG0069	glutamate synthase activity
OCAR_RS04435	COG0070	glutamate synthase
OCAR_RS04450	COG1595	DNA-templated transcription, initiation
OCAR_RS04455	COG0071	Belongs to the small heat shock protein (HSP20) family
OCAR_RS04470	COG0583	DNA-binding transcription factor activity
OCAR_RS04475	COG0483	inositol monophosphate 1-phosphatase activity
OCAR_RS04610	COG4397	Mu-like prophage major head subunit gpT
OCAR_RS04655	COG1012	belongs to the aldehyde dehydrogenase family
OCAR_RS04660	COG1414	Transcriptional regulator
OCAR_RS04665	COG1024	Enoyl-CoA hydratase
OCAR_RS04690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OCAR_RS04700	COG1053	succinate dehydrogenase
OCAR_RS04700	COG0431	NADPH-dependent FMN reductase
OCAR_RS04700	COG3976	FMN-binding domain protein
OCAR_RS04710	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
OCAR_RS04710	COG0778	Nitroreductase
OCAR_RS04715	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OCAR_RS04720	COG1920	GTP binding
OCAR_RS04725	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
OCAR_RS04835	COG4263	nitrous-oxide reductase activity
OCAR_RS04870	COG0826	peptidase U32
OCAR_RS04885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OCAR_RS04895	COG2223	nitrite transmembrane transporter activity
OCAR_RS04900	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OCAR_RS04905	COG1140	nitrate reductase beta subunit
OCAR_RS04910	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OCAR_RS04915	COG2181	nitrate reductase activity
OCAR_RS04920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCAR_RS04930	COG0521	Mo-molybdopterin cofactor biosynthetic process
OCAR_RS04935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCAR_RS04940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OCAR_RS04945	COG1120	ATPase activity
OCAR_RS04950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCAR_RS04960	COG3023	N-Acetylmuramoyl-L-alanine amidase
OCAR_RS04975	COG1278	Cold shock
OCAR_RS04980	COG3768	UPF0283 membrane protein
OCAR_RS04985	COG3106	COG3106 Predicted ATPase
OCAR_RS04990	COG1272	protein, Hemolysin III
OCAR_RS04995	COG3387	PFAM Glycoside hydrolase 15-related
OCAR_RS05000	COG0561	phosphatase activity
OCAR_RS05005	COG3265	gluconokinase activity
OCAR_RS05010	COG0363	glucosamine-6-phosphate deaminase activity
OCAR_RS05015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OCAR_RS05020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OCAR_RS05025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OCAR_RS05050	COG0655	NAD(P)H dehydrogenase (quinone) activity
OCAR_RS05055	COG1741	Belongs to the pirin family
OCAR_RS05060	COG0583	DNA-binding transcription factor activity
OCAR_RS05065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OCAR_RS05075	COG0469	pyruvate kinase activity
OCAR_RS05090	COG3750	Belongs to the UPF0335 family
OCAR_RS05100	COG2989	Protein conserved in bacteria
OCAR_RS05105	COG2204	response regulator
OCAR_RS05110	COG1164	Oligoendopeptidase f
OCAR_RS05160	COG1012	belongs to the aldehyde dehydrogenase family
OCAR_RS05165	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OCAR_RS05170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OCAR_RS05175	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OCAR_RS05205	COG3300	MHYT domain
OCAR_RS05205	COG5001	Diguanylate cyclase
OCAR_RS05210	COG3842	ATPase activity
OCAR_RS05215	COG1176	ABC-type spermidine putrescine transport system, permease component I
OCAR_RS05220	COG1177	transmembrane transport
OCAR_RS05245	COG1840	ABC-type Fe3 transport system, periplasmic component
OCAR_RS05250	COG2205	protein histidine kinase activity
OCAR_RS05275	COG0583	DNA-binding transcription factor activity
OCAR_RS05280	COG0492	ferredoxin-NADP+ reductase activity
OCAR_RS05285	COG1522	sequence-specific DNA binding
OCAR_RS05295	COG2259	Doxx family
OCAR_RS05305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OCAR_RS05310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OCAR_RS05330	COG0505	Belongs to the CarA family
OCAR_RS05345	COG0640	Transcriptional regulator
OCAR_RS05355	COG0358	DNA primase activity
OCAR_RS05360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OCAR_RS05375	COG2951	lytic endotransglycosylase activity
OCAR_RS05390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCAR_RS05395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCAR_RS05405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OCAR_RS05415	COG1959	2 iron, 2 sulfur cluster binding
OCAR_RS05425	COG1305	Transglutaminase-like
OCAR_RS05430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCAR_RS05445	COG0437	4 iron, 4 sulfur cluster binding
OCAR_RS05450	COG2864	formate dehydrogenase
OCAR_RS05460	COG1921	L-seryl-tRNASec selenium transferase activity
OCAR_RS05495	COG1201	RNA secondary structure unwinding
OCAR_RS05505	COG1793	dna ligase
OCAR_RS05510	COG1573	uracil-dna glycosylase
OCAR_RS05525	COG0587	DNA-directed DNA polymerase activity
OCAR_RS05540	COG0640	Transcriptional regulator
OCAR_RS05545	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OCAR_RS05550	COG3258	Cytochrome c
OCAR_RS05580	COG0737	Belongs to the 5'-nucleotidase family
OCAR_RS05600	COG2391	methyltransferase activity
OCAR_RS05605	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OCAR_RS05615	COG1320	monovalent cation:proton antiporter activity
OCAR_RS05620	COG2212	antiporter activity
OCAR_RS05630	COG0651	ATP synthesis coupled electron transport
OCAR_RS05635	COG1006	Multisubunit Na H antiporter MnhC subunit
OCAR_RS05640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OCAR_RS05640	COG2111	Na H antiporter
OCAR_RS05665	COG1611	Belongs to the LOG family
OCAR_RS05680	COG0482	sulfurtransferase activity
OCAR_RS05700	COG1766	The M ring may be actively involved in energy transduction
OCAR_RS05705	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OCAR_RS05715	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OCAR_RS05720	COG2204	response regulator
OCAR_RS05725	COG0512	Glutamine amidotransferase of anthranilate synthase
OCAR_RS05725	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OCAR_RS05735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OCAR_RS05740	COG3237	CsbD-like
OCAR_RS05755	COG1024	Enoyl-CoA hydratase
OCAR_RS05755	COG1250	3-hydroxyacyl-CoA dehydrogenase
OCAR_RS05780	COG1309	transcriptional regulator
OCAR_RS05800	COG0275	rRNA processing
OCAR_RS05815	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OCAR_RS05825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OCAR_RS05835	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OCAR_RS05845	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OCAR_RS05850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OCAR_RS05855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OCAR_RS05865	COG1181	Belongs to the D-alanine--D-alanine ligase family
OCAR_RS05870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OCAR_RS05875	COG0849	cell division
OCAR_RS05880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OCAR_RS05890	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCAR_RS05900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OCAR_RS05905	COG0006	proline dipeptidase activity
OCAR_RS05915	COG2264	protein methyltransferase activity
OCAR_RS05940	COG0842	Transport permease protein
OCAR_RS05945	COG1131	(ABC) transporter
OCAR_RS05950	COG0210	DNA helicase
OCAR_RS05960	COG0277	FAD linked oxidase domain protein
OCAR_RS05980	COG0114	fumarate hydratase activity
OCAR_RS05990	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OCAR_RS06000	COG0330	HflC and HflK could
OCAR_RS06005	COG0330	HflC and HflK could
OCAR_RS06020	COG0560	Phosphoserine phosphatase
OCAR_RS06020	COG3830	Belongs to the UPF0237 family
OCAR_RS06025	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OCAR_RS06040	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OCAR_RS06055	COG0028	Belongs to the TPP enzyme family
OCAR_RS06060	COG0440	acetolactate synthase activity
OCAR_RS06065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OCAR_RS06070	COG1881	PFAM PEBP family protein
OCAR_RS06075	COG2326	polyphosphate kinase activity
OCAR_RS06080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OCAR_RS06105	COG2186	Transcriptional regulator
OCAR_RS06110	COG0277	FAD linked oxidase domain protein
OCAR_RS06130	COG0318	PFAM AMP-dependent synthetase and ligase
OCAR_RS06165	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OCAR_RS06195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OCAR_RS06200	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OCAR_RS06205	COG1278	Cold shock
OCAR_RS06225	COG0179	Fumarylacetoacetate (FAA) hydrolase
OCAR_RS06230	COG1132	(ABC) transporter
OCAR_RS06240	COG0859	PFAM glycosyl transferase family 9
OCAR_RS06245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OCAR_RS06250	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OCAR_RS06265	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OCAR_RS06265	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OCAR_RS06285	COG0673	inositol 2-dehydrogenase activity
OCAR_RS06295	COG0728	peptidoglycan biosynthetic process
OCAR_RS06320	COG0438	transferase activity, transferring glycosyl groups
OCAR_RS06335	COG4948	Mandelate Racemase Muconate Lactonizing
OCAR_RS06340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OCAR_RS06345	COG1127	ABC transporter
OCAR_RS06350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OCAR_RS06350	COG3218	ABC-type transport auxiliary lipoprotein component
OCAR_RS06355	COG0837	glucose binding
OCAR_RS06370	COG0633	Ferredoxin
OCAR_RS06375	COG0492	ferredoxin-NADP+ reductase activity
OCAR_RS06385	COG0392	lysyltransferase activity
OCAR_RS06390	COG3685	Protein conserved in bacteria
OCAR_RS06425	COG1749	Flagellar hook protein flgE
OCAR_RS06430	COG1256	bacterial-type flagellum assembly
OCAR_RS06440	COG5443	negative regulation of bacterial-type flagellum assembly
OCAR_RS06480	COG1706	bacterial-type flagellum-dependent cell motility
OCAR_RS06500	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OCAR_RS06510	COG4786	Flagellar basal body rod
OCAR_RS06515	COG4786	Flagellar basal body rod
OCAR_RS06545	COG1338	Plays a role in the flagellum-specific transport system
OCAR_RS06560	COG1558	bacterial-type flagellum-dependent cell motility
OCAR_RS06565	COG1677	Flagellar hook-basal body complex protein FliE
OCAR_RS06570	COG1987	bacterial-type flagellum assembly
OCAR_RS06575	COG1684	flagellar biosynthetic protein fliR
OCAR_RS06580	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OCAR_RS06620	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OCAR_RS06620	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OCAR_RS06650	COG2814	Major facilitator Superfamily
OCAR_RS06695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OCAR_RS06700	COG1742	UPF0060 membrane protein
OCAR_RS06705	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OCAR_RS06710	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OCAR_RS06710	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OCAR_RS06715	COG0509	glycine decarboxylation via glycine cleavage system
OCAR_RS06720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OCAR_RS06725	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OCAR_RS06735	COG4651	solute:proton antiporter activity
OCAR_RS06735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OCAR_RS06745	COG0538	isocitrate dehydrogenase activity
OCAR_RS06780	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OCAR_RS06785	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OCAR_RS06790	COG0047	phosphoribosylformylglycinamidine synthase activity
OCAR_RS06795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OCAR_RS06810	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
OCAR_RS06815	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OCAR_RS06820	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OCAR_RS06825	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OCAR_RS06830	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OCAR_RS06845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OCAR_RS06900	COG3191	aminopeptidase activity
OCAR_RS06905	COG0785	Cytochrome C biogenesis protein
OCAR_RS06950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OCAR_RS06960	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OCAR_RS06960	COG3608	succinylglutamate desuccinylase aspartoacylase
OCAR_RS06965	COG2068	MobA-Related Protein
OCAR_RS06995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OCAR_RS07010	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OCAR_RS07015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OCAR_RS07045	COG0459	protein refolding
OCAR_RS07050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OCAR_RS07060	COG1028	Short-chain dehydrogenase reductase Sdr
OCAR_RS07070	COG1058	Belongs to the CinA family
OCAR_RS07070	COG1546	Belongs to the CinA family
OCAR_RS07075	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
OCAR_RS07080	COG1064	alcohol dehydrogenase
OCAR_RS07150	COG0859	PFAM glycosyl transferase family 9
OCAR_RS07215	COG0629	single-stranded DNA binding
OCAR_RS07220	COG0328	RNA-DNA hybrid ribonuclease activity
OCAR_RS07315	COG0305	Participates in initiation and elongation during chromosome replication
OCAR_RS07570	COG0517	IMP dehydrogenase activity
OCAR_RS07575	COG1752	Esterase of the alpha-beta hydrolase superfamily
OCAR_RS07590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OCAR_RS07595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OCAR_RS07600	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OCAR_RS07605	COG2080	2 iron, 2 sulfur cluster binding
OCAR_RS07610	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OCAR_RS07625	COG0302	gtp cyclohydrolase
OCAR_RS07630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OCAR_RS07650	COG2201	protein-glutamate methylesterase activity
OCAR_RS07655	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OCAR_RS07665	COG4771	TonB-dependent receptor
OCAR_RS07675	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OCAR_RS07705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OCAR_RS07725	COG1414	Transcriptional regulator
OCAR_RS07750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCAR_RS07795	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OCAR_RS07800	COG0081	regulation of translation
OCAR_RS07805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OCAR_RS07810	COG0222	ribosome binding
OCAR_RS07815	COG0085	RNA polymerase activity
OCAR_RS07820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OCAR_RS07825	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OCAR_RS07830	COG1132	(ABC) transporter
OCAR_RS07850	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OCAR_RS07855	COG0049	tRNA binding
OCAR_RS07860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OCAR_RS07865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OCAR_RS07870	COG0051	transcription antitermination factor activity, RNA binding
OCAR_RS07875	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OCAR_RS07880	COG0088	Forms part of the polypeptide exit tunnel
OCAR_RS07885	COG0089	rRNA binding
OCAR_RS07890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OCAR_RS07895	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OCAR_RS07900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OCAR_RS07905	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OCAR_RS07910	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OCAR_RS07920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OCAR_RS07925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OCAR_RS07930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OCAR_RS07935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OCAR_RS07940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OCAR_RS07945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OCAR_RS07950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OCAR_RS07955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OCAR_RS07960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OCAR_RS07965	COG1841	ribosomal large subunit assembly
OCAR_RS07970	COG0200	Binds to the 23S rRNA
OCAR_RS07980	COG0563	adenylate kinase activity
OCAR_RS07985	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OCAR_RS07990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OCAR_RS07995	COG0202	RNA polymerase activity
OCAR_RS08000	COG0203	ribosomal protein L17
OCAR_RS08010	COG1028	Short-chain dehydrogenase reductase Sdr
OCAR_RS08025	COG1733	regulation of RNA biosynthetic process
OCAR_RS08035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OCAR_RS08040	COG0564	pseudouridine synthase activity
OCAR_RS08060	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OCAR_RS08085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OCAR_RS08100	COG0702	epimerase
OCAR_RS08105	COG1073	alpha beta
OCAR_RS08110	COG1073	alpha beta
OCAR_RS08115	COG0583	DNA-binding transcription factor activity
OCAR_RS08140	COG1846	Transcriptional regulator
OCAR_RS08145	COG1764	response to oxidative stress
OCAR_RS08150	COG0596	Alpha beta hydrolase
OCAR_RS08155	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OCAR_RS08160	COG0697	spore germination
OCAR_RS08165	COG0415	Belongs to the DNA photolyase family
OCAR_RS08170	COG0450	alkyl hydroperoxide reductase
OCAR_RS08180	COG1254	Belongs to the acylphosphatase family
OCAR_RS08195	COG0321	lipoyl(octanoyl) transferase activity
OCAR_RS08210	COG2258	MOSC domain
OCAR_RS08220	COG0405	Gamma-glutamyltransferase
OCAR_RS08235	COG0726	polysaccharide deacetylase
OCAR_RS08285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OCAR_RS08300	COG1686	Belongs to the peptidase S11 family
OCAR_RS08315	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OCAR_RS08355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OCAR_RS08365	COG0784	Response regulator, receiver
OCAR_RS08375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OCAR_RS08395	COG0557	exoribonuclease II activity
OCAR_RS08400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OCAR_RS08410	COG0758	DNA mediated transformation
OCAR_RS08415	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OCAR_RS08420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OCAR_RS08425	COG0540	Belongs to the ATCase OTCase family
OCAR_RS08435	COG1960	acyl-CoA dehydrogenase activity
OCAR_RS08445	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OCAR_RS08450	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OCAR_RS08460	COG0154	amidase activity
OCAR_RS08480	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OCAR_RS08490	COG0583	DNA-binding transcription factor activity
OCAR_RS08500	COG1335	isochorismatase
OCAR_RS08540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OCAR_RS08590	COG0741	lytic transglycosylase activity
OCAR_RS08595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OCAR_RS08600	COG1970	mechanosensitive ion channel activity
OCAR_RS08605	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OCAR_RS08625	COG1758	RNA polymerase activity
OCAR_RS08635	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OCAR_RS08640	COG0736	holo-[acyl-carrier-protein] synthase activity
OCAR_RS08645	COG0681	Belongs to the peptidase S26 family
OCAR_RS08650	COG0571	ribonuclease III activity
OCAR_RS08655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OCAR_RS08670	COG1381	Involved in DNA repair and RecF pathway recombination
OCAR_RS08680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OCAR_RS08690	COG1914	H( )-stimulated, divalent metal cation uptake system
OCAR_RS08700	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OCAR_RS08710	COG0113	porphobilinogen synthase activity
OCAR_RS08730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OCAR_RS08735	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OCAR_RS08740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCAR_RS08740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCAR_RS08750	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OCAR_RS08755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCAR_RS08760	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OCAR_RS08765	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OCAR_RS08800	COG0416	fatty acid biosynthetic process
OCAR_RS08805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OCAR_RS08810	COG0776	regulation of translation
OCAR_RS08820	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OCAR_RS08820	COG2755	lipolytic protein G-D-S-L family
OCAR_RS08835	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OCAR_RS08875	COG1612	heme a metabolic process
OCAR_RS08880	COG0672	)-iron permease
OCAR_RS08900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OCAR_RS08905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OCAR_RS08930	COG0174	glutamine synthetase
OCAR_RS08935	COG0347	Belongs to the P(II) protein family
OCAR_RS08940	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OCAR_RS08940	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OCAR_RS08955	COG0544	peptidyl-prolyl cis-trans isomerase activity
OCAR_RS08960	COG0740	serine-type endopeptidase activity
OCAR_RS08965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OCAR_RS08970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OCAR_RS08985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCAR_RS08995	COG2195	Cleaves the N-terminal amino acid of tripeptides
OCAR_RS09005	COG0776	regulation of translation
OCAR_RS09015	COG0473	3-isopropylmalate dehydrogenase activity
OCAR_RS09025	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCAR_RS09030	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCAR_RS09040	COG0649	NAD binding
OCAR_RS09045	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
OCAR_RS09050	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OCAR_RS09060	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OCAR_RS09065	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCAR_RS09075	COG0713	ATP synthesis coupled electron transport
OCAR_RS09090	COG1007	ATP synthesis coupled electron transport
OCAR_RS09105	COG0346	lactoylglutathione lyase activity
OCAR_RS09120	COG4774	siderophore transport
OCAR_RS09120	COG4774	siderophore transport
OCAR_RS09130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCAR_RS09140	COG0442	prolyl-tRNA aminoacylation
OCAR_RS09150	COG1136	(ABC) transporter
OCAR_RS09180	COG0052	Belongs to the universal ribosomal protein uS2 family
OCAR_RS09185	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OCAR_RS09190	COG0528	UMP kinase activity
OCAR_RS09195	COG0233	cytoplasmic translational termination
OCAR_RS09200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OCAR_RS09210	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OCAR_RS09215	COG0750	zinc metalloprotease
OCAR_RS09220	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCAR_RS09230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OCAR_RS09235	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCAR_RS09240	COG3494	Protein of unknown function (DUF1009)
OCAR_RS09245	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCAR_RS09255	COG0372	Belongs to the citrate synthase family
OCAR_RS09260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCAR_RS09265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCAR_RS09270	COG2333	competence protein COMEC
OCAR_RS09270	COG0658	competence protein
OCAR_RS09275	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OCAR_RS09280	COG0745	RESPONSE REGULATOR receiver
OCAR_RS09285	COG0784	Response regulator, receiver
OCAR_RS09290	COG2205	protein histidine kinase activity
OCAR_RS09300	COG0511	ligase activity, forming carbon-carbon bonds
OCAR_RS09305	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OCAR_RS09320	COG0436	Aminotransferase
OCAR_RS09325	COG1530	ribonuclease E activity
OCAR_RS09325	COG1530	ribonuclease E activity
OCAR_RS09330	COG0860	N-Acetylmuramoyl-L-alanine amidase
OCAR_RS09335	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OCAR_RS09345	COG0590	tRNA wobble adenosine to inosine editing
OCAR_RS09355	COG0739	heme binding
OCAR_RS09360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OCAR_RS09370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OCAR_RS09375	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OCAR_RS09380	COG2945	thiolester hydrolase activity
OCAR_RS09385	COG1104	cysteine desulfurase activity
OCAR_RS09390	COG0719	Fe-S assembly protein
OCAR_RS09395	COG0396	ATPase activity
OCAR_RS09400	COG0719	Fe-S assembly protein
OCAR_RS09405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OCAR_RS09410	COG2151	metal-sulfur cluster biosynthetic enzyme
OCAR_RS09415	COG0316	Belongs to the HesB IscA family
OCAR_RS09420	COG3706	GGDEF domain
OCAR_RS09425	COG0513	Belongs to the DEAD box helicase family
OCAR_RS09435	COG0187	DNA topoisomerase II activity
OCAR_RS09440	COG0586	Pfam SNARE associated Golgi protein
OCAR_RS09445	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OCAR_RS09455	COG3243	poly(R)-hydroxyalkanoic acid synthase
OCAR_RS09465	COG0436	Aminotransferase
OCAR_RS09475	COG1494	fructose-1,6-bisphosphatase
OCAR_RS09480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCAR_RS09485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OCAR_RS09495	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OCAR_RS09500	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OCAR_RS09505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OCAR_RS09510	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OCAR_RS09550	COG1278	Cold shock
OCAR_RS09635	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OCAR_RS09640	COG0671	phosphoesterase, PA-phosphatase related
OCAR_RS09645	COG0463	Glycosyl transferase, family 2
OCAR_RS09655	COG0626	cystathionine gamma-synthase activity
OCAR_RS09660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCAR_RS09665	COG4597	amino acid ABC transporter
OCAR_RS09670	COG0765	amino acid transport
OCAR_RS09675	COG1126	abc transporter atp-binding protein
OCAR_RS09685	COG1538	Outer membrane efflux protein
OCAR_RS09710	COG1024	Enoyl-CoA hydratase
OCAR_RS09715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OCAR_RS09720	COG1960	acyl-CoA dehydrogenase activity
OCAR_RS09725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OCAR_RS09730	COG0583	DNA-binding transcription factor activity
OCAR_RS09735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OCAR_RS09745	COG0129	dihydroxy-acid dehydratase activity
OCAR_RS09760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCAR_RS09765	COG4172	Belongs to the ABC transporter superfamily
OCAR_RS09795	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OCAR_RS09810	COG0525	valine-tRNA ligase activity
OCAR_RS09815	COG2094	Belongs to the DNA glycosylase MPG family
OCAR_RS09820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OCAR_RS09835	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OCAR_RS09835	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OCAR_RS09855	COG5000	phosphorelay sensor kinase activity
OCAR_RS09860	COG2204	response regulator
OCAR_RS09865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OCAR_RS09870	COG1923	regulation of RNA biosynthetic process
OCAR_RS09875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OCAR_RS09880	COG3956	TIGRFAM MazG family protein
OCAR_RS09885	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OCAR_RS09890	COG2226	methyltransferase
OCAR_RS09900	COG0438	transferase activity, transferring glycosyl groups
OCAR_RS09940	COG0489	protein tyrosine kinase activity
OCAR_RS09940	COG3206	protein involved in exopolysaccharide biosynthesis
OCAR_RS09975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OCAR_RS09980	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OCAR_RS09980	COG0321	lipoyl(octanoyl) transferase activity
OCAR_RS09985	COG0084	hydrolase, TatD family'
OCAR_RS09995	COG0470	DNA polymerase III
OCAR_RS10000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OCAR_RS10005	COG1686	Belongs to the peptidase S11 family
OCAR_RS10225	COG0582	viral genome integration into host DNA
OCAR_RS10235	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
OCAR_RS10255	COG2132	Multicopper oxidase
OCAR_RS10260	COG3842	ATPase activity
OCAR_RS10265	COG1177	transmembrane transport
OCAR_RS10280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCAR_RS10290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OCAR_RS10320	COG0473	3-isopropylmalate dehydrogenase activity
OCAR_RS10320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OCAR_RS10325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OCAR_RS10330	COG1984	allophanate hydrolase subunit 2
OCAR_RS10335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OCAR_RS10340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OCAR_RS10350	COG1253	flavin adenine dinucleotide binding
OCAR_RS10355	COG1183	phosphatidylcholine synthase activity
OCAR_RS10360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCAR_RS10365	COG3785	DNA binding
OCAR_RS10370	COG4774	siderophore transport
OCAR_RS10400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OCAR_RS10425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OCAR_RS10430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OCAR_RS10470	COG0840	transmembrane signaling receptor activity
OCAR_RS10480	COG0343	queuine tRNA-ribosyltransferase activity
OCAR_RS10485	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OCAR_RS10500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OCAR_RS10510	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OCAR_RS10515	COG2095	MarC family integral membrane protein
OCAR_RS10520	COG0629	single-stranded DNA binding
OCAR_RS10535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OCAR_RS10585	COG0693	protein deglycase activity
OCAR_RS10590	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OCAR_RS10610	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCAR_RS10615	COG1862	Preprotein translocase
OCAR_RS10635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OCAR_RS10645	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OCAR_RS10650	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OCAR_RS10655	COG0805	protein transport
OCAR_RS10660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OCAR_RS10665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OCAR_RS10675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OCAR_RS10680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OCAR_RS10685	COG1472	Belongs to the glycosyl hydrolase 3 family
OCAR_RS10695	COG0018	arginyl-trna synthetase
OCAR_RS10700	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OCAR_RS10705	COG0316	Belongs to the HesB IscA family
OCAR_RS10710	COG0708	Exodeoxyribonuclease III
OCAR_RS10720	COG0129	dihydroxy-acid dehydratase activity
OCAR_RS10730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCAR_RS10745	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCAR_RS10750	COG0022	dehydrogenase e1 component
OCAR_RS10750	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCAR_RS10755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OCAR_RS10775	COG0431	NADPH-dependent FMN reductase
OCAR_RS10780	COG0148	phosphopyruvate hydratase activity
OCAR_RS10785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OCAR_RS10800	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OCAR_RS10820	COG0504	CTP synthase activity
OCAR_RS10830	COG0149	triose-phosphate isomerase activity
OCAR_RS10840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OCAR_RS10845	COG0134	indole-3-glycerol-phosphate synthase activity
OCAR_RS10850	COG0315	cyclic pyranopterin monophosphate synthase activity
OCAR_RS10855	COG0303	'Molybdopterin
OCAR_RS10865	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OCAR_RS10945	COG3045	CreA protein
OCAR_RS10970	COG0281	malic enzyme
OCAR_RS10970	COG0280	phosphate acetyltransferase
OCAR_RS10975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OCAR_RS10980	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
OCAR_RS10990	COG0248	Ppx GppA phosphatase
OCAR_RS10995	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OCAR_RS11010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OCAR_RS11015	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OCAR_RS11020	COG0861	Integral membrane protein TerC family
OCAR_RS11025	COG0105	UTP biosynthetic process
OCAR_RS11040	COG0488	(ABC) transporter
OCAR_RS11055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OCAR_RS11065	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OCAR_RS11080	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OCAR_RS11100	COG0477	Major facilitator Superfamily
OCAR_RS11105	COG0194	GDP metabolic process
OCAR_RS11110	COG1561	YicC-like family, N-terminal region
OCAR_RS11115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OCAR_RS11120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCAR_RS11125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OCAR_RS11135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OCAR_RS11140	COG0360	Binds together with S18 to 16S ribosomal RNA
OCAR_RS11145	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OCAR_RS11155	COG0359	binds to the 23S rRNA
OCAR_RS11165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OCAR_RS11170	COG0305	Participates in initiation and elongation during chromosome replication
OCAR_RS11175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OCAR_RS11185	COG1286	toxin biosynthetic process
OCAR_RS11190	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OCAR_RS11200	COG0300	oxidoreductase activity
OCAR_RS11220	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OCAR_RS11230	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OCAR_RS11265	COG1393	Belongs to the ArsC family
OCAR_RS11275	COG0038	chloride channel
OCAR_RS11360	COG0464	growth
OCAR_RS11375	COG2948	multi-organism process
OCAR_RS11405	COG3451	type IV secretory pathway VirB4
OCAR_RS11420	COG4962	Type ii secretion system protein e
OCAR_RS11485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OCAR_RS11505	COG5489	Protein of unknown function (DUF736)
OCAR_RS11555	COG5489	Protein of unknown function (DUF736)
OCAR_RS11585	COG0519	Catalyzes the synthesis of GMP from XMP
OCAR_RS11585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OCAR_RS11590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCAR_RS11590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCAR_RS11610	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OCAR_RS11620	COG1671	Belongs to the UPF0178 family
OCAR_RS11625	COG0488	(ABC) transporter
OCAR_RS11630	COG0583	DNA-binding transcription factor activity
OCAR_RS11660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCAR_RS11665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCAR_RS11690	COG4774	siderophore transport
OCAR_RS11720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OCAR_RS11725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OCAR_RS11730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCAR_RS11735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCAR_RS11740	COG0604	alcohol dehydrogenase
OCAR_RS11740	COG3321	synthase
OCAR_RS11745	COG1560	Kdo2-lipid A biosynthetic process
OCAR_RS11765	COG3158	transport of potassium into the cell
OCAR_RS11775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OCAR_RS11780	COG1183	phosphatidylcholine synthase activity
OCAR_RS11785	COG0688	phosphatidylethanolamine metabolic process
OCAR_RS11790	COG5265	(ABC) transporter
OCAR_RS11805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OCAR_RS11815	COG0215	cysteine-tRNA ligase activity
OCAR_RS11835	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OCAR_RS11840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCAR_RS11860	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OCAR_RS11865	COG0546	phosphoglycolate phosphatase activity
OCAR_RS11875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCAR_RS11885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OCAR_RS11890	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OCAR_RS11895	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OCAR_RS11905	COG1392	Phosphate transport regulator
OCAR_RS11910	COG0306	phosphate transporter
OCAR_RS11915	COG1285	pathogenesis
OCAR_RS11920	COG2205	protein histidine kinase activity
OCAR_RS11935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OCAR_RS11945	COG2832	Protein of unknown function (DUF454)
OCAR_RS11960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OCAR_RS11980	COG0045	succinate-CoA ligase (ADP-forming) activity
OCAR_RS11985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OCAR_RS11990	COG1802	Transcriptional regulator
OCAR_RS11995	COG0179	Fumarylacetoacetate (FAA) hydrolase
OCAR_RS12005	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OCAR_RS12010	COG2084	Dehydrogenase
OCAR_RS12015	COG3622	Belongs to the hyi family
OCAR_RS12020	COG3960	tartronate-semialdehyde synthase activity
OCAR_RS12025	COG1414	Transcriptional regulator
OCAR_RS12035	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OCAR_RS12040	COG0045	succinate-CoA ligase (ADP-forming) activity
OCAR_RS12045	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OCAR_RS12050	COG2205	protein histidine kinase activity
OCAR_RS12055	COG0745	RESPONSE REGULATOR receiver
OCAR_RS12065	COG3088	subunit of a heme lyase
OCAR_RS12070	COG1138	Cytochrome C-type biogenesis protein
OCAR_RS12075	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OCAR_RS12080	COG4235	cytochrome complex assembly
OCAR_RS12240	COG4695	Portal protein
OCAR_RS12270	COG0477	Major facilitator Superfamily
OCAR_RS12275	COG2983	Belongs to the UPF0260 family
OCAR_RS12280	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OCAR_RS12305	COG0861	Integral membrane protein TerC family
OCAR_RS12345	COG2205	protein histidine kinase activity
OCAR_RS12355	COG2166	iron-sulfur cluster assembly
OCAR_RS12370	COG4957	zinc ion binding
OCAR_RS12390	COG0433	COG0433 Predicted ATPase
OCAR_RS12400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OCAR_RS12410	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OCAR_RS12460	COG0427	acetyl-CoA hydrolase
OCAR_RS12480	COG1473	amidohydrolase
OCAR_RS12505	COG2409	Drug exporters of the RND superfamily
OCAR_RS12510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OCAR_RS12515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OCAR_RS12520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCAR_RS12530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OCAR_RS12535	COG1657	PFAM Prenyltransferase squalene oxidase
OCAR_RS12540	COG1233	COG1233 Phytoene dehydrogenase and related
OCAR_RS12545	COG1562	ergosterol biosynthetic process
OCAR_RS12550	COG1562	ergosterol biosynthetic process
OCAR_RS12560	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OCAR_RS12565	COG1054	Belongs to the UPF0176 family
OCAR_RS12570	COG2900	Belongs to the SlyX family
OCAR_RS12575	COG0656	L-ascorbic acid biosynthetic process
OCAR_RS12600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCAR_RS12610	COG1309	transcriptional regulator
OCAR_RS12630	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OCAR_RS12640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OCAR_RS12650	COG0247	lactate metabolic process
OCAR_RS12650	COG0277	FAD linked oxidase domain protein
OCAR_RS12660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OCAR_RS12690	COG3383	formate dehydrogenase (NAD+) activity
OCAR_RS12695	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OCAR_RS12735	COG0303	'Molybdopterin
OCAR_RS12740	COG1763	Mo-molybdopterin cofactor biosynthetic process
OCAR_RS12745	COG0746	molybdenum cofactor guanylyltransferase activity
OCAR_RS12765	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OCAR_RS12775	COG0848	biopolymer transport protein
OCAR_RS12785	COG3128	pkhd-type hydroxylase
OCAR_RS12790	COG4774	siderophore transport
OCAR_RS12800	COG0156	8-amino-7-oxononanoate synthase activity
OCAR_RS12805	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OCAR_RS12810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OCAR_RS12820	COG0667	Aldo Keto reductase
OCAR_RS12825	COG5001	Diguanylate cyclase
OCAR_RS12825	COG3300	MHYT domain
OCAR_RS12835	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OCAR_RS12845	COG1012	belongs to the aldehyde dehydrogenase family
OCAR_RS12860	COG3181	Tripartite tricarboxylate transporter family receptor
OCAR_RS12865	COG0583	DNA-binding transcription factor activity
OCAR_RS12870	COG0028	Belongs to the TPP enzyme family
OCAR_RS12875	COG1414	Transcriptional regulator
OCAR_RS12885	COG0477	Major facilitator Superfamily
OCAR_RS12895	COG1414	Transcriptional regulator
OCAR_RS12905	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OCAR_RS12910	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OCAR_RS12915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCAR_RS12915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OCAR_RS12920	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCAR_RS12925	COG3706	GGDEF domain
OCAR_RS12970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCAR_RS12980	COG0437	4 iron, 4 sulfur cluster binding
OCAR_RS13005	COG1176	ABC-type spermidine putrescine transport system, permease component I
OCAR_RS13010	COG3842	ATPase activity
OCAR_RS13015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OCAR_RS13020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OCAR_RS13030	COG0318	PFAM AMP-dependent synthetase and ligase
OCAR_RS13070	COG0625	glutathione transferase activity
OCAR_RS13110	COG4948	Mandelate Racemase Muconate Lactonizing
OCAR_RS13115	COG1414	Transcriptional regulator
OCAR_RS13120	COG0463	Glycosyl transferase, family 2
OCAR_RS13120	COG1216	Glycosyl transferase, family 2
OCAR_RS13130	COG0583	DNA-binding transcription factor activity
OCAR_RS13150	COG1172	Belongs to the binding-protein-dependent transport system permease family
OCAR_RS13170	COG0318	PFAM AMP-dependent synthetase and ligase
OCAR_RS13180	COG0625	glutathione transferase activity
OCAR_RS13245	COG0045	succinate-CoA ligase (ADP-forming) activity
OCAR_RS13245	COG1042	CoA-binding domain protein
OCAR_RS13245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCAR_RS13250	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
OCAR_RS13265	COG0517	IMP dehydrogenase activity
OCAR_RS13275	COG0071	Belongs to the small heat shock protein (HSP20) family
OCAR_RS13290	COG1127	ABC transporter
OCAR_RS13295	COG3218	ABC-type transport auxiliary lipoprotein component
OCAR_RS13295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OCAR_RS13305	COG1648	precorrin-2 dehydrogenase activity
OCAR_RS13305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OCAR_RS13310	COG0243	molybdopterin cofactor binding
OCAR_RS13320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCAR_RS13330	COG2201	protein-glutamate methylesterase activity
OCAR_RS13350	COG1120	ATPase activity
OCAR_RS13370	COG3842	ATPase activity
OCAR_RS13460	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OCAR_RS13480	COG3052	prosthetic group binding
OCAR_RS13500	COG3181	Tripartite tricarboxylate transporter family receptor
OCAR_RS13520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCAR_RS13525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCAR_RS13535	COG1309	transcriptional regulator
OCAR_RS13545	COG0519	Catalyzes the synthesis of GMP from XMP
OCAR_RS13550	COG5001	Diguanylate cyclase
OCAR_RS13565	COG1960	acyl-CoA dehydrogenase activity
OCAR_RS13570	COG1024	Enoyl-CoA hydratase
OCAR_RS13575	COG0123	including yeast histone deacetylase and acetoin utilization protein
OCAR_RS13580	COG1722	exodeoxyribonuclease VII activity
OCAR_RS13585	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OCAR_RS13590	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OCAR_RS13595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OCAR_RS13610	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OCAR_RS13615	COG0406	alpha-ribazole phosphatase activity
OCAR_RS13620	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCAR_RS13645	COG0484	heat shock protein binding
OCAR_RS13655	COG0259	pyridoxamine-phosphate oxidase activity
OCAR_RS13660	COG1028	Short-chain dehydrogenase reductase Sdr
OCAR_RS13670	COG1324	tolerance protein
OCAR_RS13680	COG1376	ErfK ybiS ycfS ynhG family protein
OCAR_RS13705	COG1960	acyl-CoA dehydrogenase activity
OCAR_RS13710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OCAR_RS13710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OCAR_RS13730	COG0009	L-threonylcarbamoyladenylate synthase
OCAR_RS13735	COG0277	FAD linked oxidase domain protein
OCAR_RS13740	COG2135	peptidase activity
OCAR_RS13765	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OCAR_RS13770	COG0354	folic acid binding
OCAR_RS13775	COG2818	Glycosylase
OCAR_RS13780	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
OCAR_RS13805	COG0604	alcohol dehydrogenase
OCAR_RS13810	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OCAR_RS13815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OCAR_RS13830	COG0574	Belongs to the PEP-utilizing enzyme family
OCAR_RS13830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OCAR_RS13840	COG0751	glycine-tRNA ligase activity
OCAR_RS13845	COG2852	Protein conserved in bacteria
OCAR_RS13850	COG0752	glycyl-tRNA synthetase alpha subunit
OCAR_RS13875	COG0142	geranyltranstransferase activity
OCAR_RS13880	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OCAR_RS13900	COG1573	uracil-dna glycosylase
OCAR_RS13905	COG1028	Short-chain dehydrogenase reductase Sdr
OCAR_RS13910	COG2814	Major facilitator Superfamily
OCAR_RS13955	COG0521	Mo-molybdopterin cofactor biosynthetic process
OCAR_RS13960	COG2321	neutral zinc metallopeptidase
OCAR_RS13965	COG2189	Belongs to the N(4) N(6)-methyltransferase family
OCAR_RS13975	COG0625	glutathione transferase activity
OCAR_RS13980	COG1194	a g-specific adenine glycosylase
OCAR_RS13995	COG1196	nuclear chromosome segregation
OCAR_RS14010	COG1704	LemA family
OCAR_RS14030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OCAR_RS14045	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OCAR_RS14045	COG2857	Cytochrome c1
OCAR_RS14050	COG0723	plastoquinol--plastocyanin reductase activity
OCAR_RS14055	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OCAR_RS14060	COG0602	queuosine metabolic process
OCAR_RS14070	COG0408	coproporphyrinogen oxidase activity
OCAR_RS14085	COG0617	tRNA 3'-terminal CCA addition
OCAR_RS14095	COG0494	nUDIX hydrolase
OCAR_RS14105	COG0714	Associated with various cellular activities
OCAR_RS14130	COG4771	TonB-dependent receptor
OCAR_RS14135	COG0523	cobalamin synthesis protein
OCAR_RS14205	COG2022	thiamine diphosphate biosynthetic process
OCAR_RS14215	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OCAR_RS14225	COG2204	response regulator
OCAR_RS14235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OCAR_RS14280	COG4106	trans-aconitate 2-methyltransferase activity
OCAR_RS14290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OCAR_RS14295	COG1376	ErfK ybiS ycfS ynhG family protein
OCAR_RS14305	COG2897	thiosulfate sulfurtransferase activity
OCAR_RS14320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCAR_RS14340	COG0412	Dienelactone hydrolase
OCAR_RS14345	COG1640	4-alpha-glucanotransferase
OCAR_RS14350	COG0366	Alpha amylase catalytic
OCAR_RS14355	COG0366	Alpha amylase catalytic
OCAR_RS14360	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OCAR_RS14370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OCAR_RS14400	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OCAR_RS14410	COG2079	MmgE PrpD family protein
OCAR_RS14420	COG0679	Auxin Efflux Carrier
OCAR_RS14425	COG2814	Major facilitator Superfamily
OCAR_RS14430	COG0438	transferase activity, transferring glycosyl groups
OCAR_RS14450	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OCAR_RS14475	COG4191	Histidine kinase
OCAR_RS14475	COG0784	Response regulator, receiver
OCAR_RS14480	COG2205	protein histidine kinase activity
OCAR_RS14500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCAR_RS14505	COG1116	anion transmembrane transporter activity
OCAR_RS14510	COG1028	Short-chain dehydrogenase reductase Sdr
OCAR_RS14515	COG1802	Transcriptional regulator
OCAR_RS14535	COG0840	transmembrane signaling receptor activity
OCAR_RS14545	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OCAR_RS14560	COG1595	DNA-templated transcription, initiation
OCAR_RS14585	COG2201	protein-glutamate methylesterase activity
OCAR_RS14590	COG0784	Response regulator, receiver
OCAR_RS14590	COG2198	Histidine kinase
OCAR_RS14590	COG0643	Histidine kinase
OCAR_RS14600	COG0784	Response regulator, receiver
OCAR_RS14600	COG2198	Histidine kinase
OCAR_RS14600	COG0643	Histidine kinase
OCAR_RS14635	COG1376	ErfK ybiS ycfS ynhG family protein
OCAR_RS14650	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OCAR_RS14655	COG0181	hydroxymethylbilane synthase activity
OCAR_RS14665	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OCAR_RS14670	COG4191	Histidine kinase
OCAR_RS14675	COG4566	intracellular signal transduction
OCAR_RS14685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCAR_RS14695	COG3278	Belongs to the heme-copper respiratory oxidase family
OCAR_RS14710	COG2010	Cytochrome c
OCAR_RS14745	COG0564	pseudouridine synthase activity
OCAR_RS14750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OCAR_RS14765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OCAR_RS14775	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OCAR_RS14785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OCAR_RS14810	COG2223	nitrite transmembrane transporter activity
OCAR_RS14815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCAR_RS14825	COG1304	FMN binding
OCAR_RS14835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OCAR_RS14840	COG0659	secondary active sulfate transmembrane transporter activity
OCAR_RS14855	COG0436	Aminotransferase
OCAR_RS14890	COG0625	glutathione transferase activity
OCAR_RS14900	COG0556	nucleotide-excision repair
OCAR_RS14905	COG0488	(ABC) transporter
OCAR_RS14930	COG0193	aminoacyl-tRNA hydrolase activity
OCAR_RS14935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OCAR_RS14950	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OCAR_RS14960	COG1496	oxidoreductase activity
OCAR_RS14970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OCAR_RS14985	COG2205	protein histidine kinase activity
OCAR_RS14990	COG0745	RESPONSE REGULATOR receiver
OCAR_RS14995	COG1846	Transcriptional regulator
OCAR_RS15000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OCAR_RS15005	COG0534	Mate efflux family protein
OCAR_RS15010	COG0590	tRNA wobble adenosine to inosine editing
OCAR_RS15015	COG2890	protein-(glutamine-N5) methyltransferase activity
OCAR_RS15020	COG0314	molybdopterin synthase activity
OCAR_RS15030	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OCAR_RS15035	COG0322	excinuclease ABC activity
OCAR_RS15040	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OCAR_RS15045	COG1278	Cold shock
OCAR_RS15050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OCAR_RS15070	COG1942	4-Oxalocrotonate Tautomerase
OCAR_RS15080	COG2852	Protein conserved in bacteria
OCAR_RS15095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OCAR_RS15120	COG0745	RESPONSE REGULATOR receiver
OCAR_RS15125	COG0196	riboflavin kinase activity
OCAR_RS15130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OCAR_RS15135	COG4771	TonB-dependent receptor
OCAR_RS15140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OCAR_RS15150	COG0612	Peptidase, M16
OCAR_RS15155	COG0612	Peptidase, M16
OCAR_RS15165	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OCAR_RS15170	COG0742	ribosomal rna small subunit methyltransferase
OCAR_RS15175	COG1187	pseudouridine synthase activity
OCAR_RS15180	COG0590	tRNA wobble adenosine to inosine editing
OCAR_RS15190	COG0151	Belongs to the GarS family
OCAR_RS15195	COG1570	exodeoxyribonuclease VII activity
OCAR_RS15210	COG1663	tetraacyldisaccharide 4'-kinase activity
OCAR_RS15215	COG1519	Transferase
OCAR_RS15230	COG1218	3'(2'),5'-bisphosphate nucleotidase
OCAR_RS15235	COG0312	modulator of DNA gyrase
OCAR_RS15245	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OCAR_RS15265	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OCAR_RS15270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OCAR_RS15275	COG0463	Glycosyl transferase, family 2
OCAR_RS15285	COG3416	Protein conserved in bacteria
OCAR_RS15290	COG1376	ErfK ybiS ycfS ynhG family protein
OCAR_RS15290	COG1388	LysM domain
OCAR_RS15310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OCAR_RS15315	COG0459	protein refolding
OCAR_RS15335	COG1620	l-lactate permease
OCAR_RS15340	COG4178	(ABC) transporter
OCAR_RS15355	COG0247	lactate metabolic process
OCAR_RS15360	COG0277	FAD linked oxidase domain protein
OCAR_RS15365	COG0277	FAD linked oxidase domain protein
OCAR_RS15370	COG1309	transcriptional regulator
OCAR_RS15380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCAR_RS15385	COG0037	tRNA processing
OCAR_RS15395	COG2885	chlorophyll binding
OCAR_RS15400	COG0823	Involved in the tonB-independent uptake of proteins
OCAR_RS15410	COG0848	biopolymer transport protein
OCAR_RS15435	COG0824	Thioesterase
OCAR_RS15445	COG2255	four-way junction helicase activity
OCAR_RS15455	COG0632	four-way junction helicase activity
OCAR_RS15460	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OCAR_RS15465	COG2239	Acts as a magnesium transporter
OCAR_RS15470	COG0217	transcriptional regulatory protein
OCAR_RS15475	COG1692	metallophosphoesterase
OCAR_RS15480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OCAR_RS15485	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OCAR_RS15510	COG0126	phosphoglycerate kinase activity
OCAR_RS15515	COG3588	fructose-bisphosphate aldolase
OCAR_RS15530	COG0483	inositol monophosphate 1-phosphatase activity
OCAR_RS15550	COG1132	(ABC) transporter
OCAR_RS15555	COG0254	rRNA binding
OCAR_RS15570	COG0604	alcohol dehydrogenase
OCAR_RS15570	COG1028	Short-chain dehydrogenase reductase Sdr
OCAR_RS15570	COG3321	synthase
OCAR_RS15575	COG3300	MHYT domain
OCAR_RS15575	COG5001	Diguanylate cyclase
OCAR_RS15580	COG1678	Uncharacterized ACR, COG1678
OCAR_RS15595	COG0328	RNA-DNA hybrid ribonuclease activity
OCAR_RS15600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OCAR_RS15605	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OCAR_RS15615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OCAR_RS15615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OCAR_RS15645	COG2358	TRAP transporter, solute receptor (TAXI family
OCAR_RS15715	COG3321	synthase
OCAR_RS15715	COG1028	Short-chain dehydrogenase reductase Sdr
OCAR_RS15715	COG0604	alcohol dehydrogenase
OCAR_RS15725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OCAR_RS15730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OCAR_RS15735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OCAR_RS15740	COG0405	Gamma-glutamyltransferase
OCAR_RS15745	COG4336	lyase activity
OCAR_RS15750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCAR_RS15760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCAR_RS15765	COG1802	Transcriptional regulator
OCAR_RS15780	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OCAR_RS15795	COG3706	GGDEF domain
OCAR_RS15805	COG1238	metal cluster binding
OCAR_RS15810	COG0140	phosphoribosyl-ATP diphosphatase activity
OCAR_RS15820	COG1132	(ABC) transporter
OCAR_RS15830	COG0318	PFAM AMP-dependent synthetase and ligase
OCAR_RS15845	COG1028	Short-chain dehydrogenase reductase Sdr
OCAR_RS15855	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OCAR_RS15860	COG4208	sulfate ABC transporter
OCAR_RS15865	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OCAR_RS15870	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OCAR_RS15875	COG0175	sulfate reduction
OCAR_RS15880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OCAR_RS15880	COG1648	precorrin-2 dehydrogenase activity
OCAR_RS15890	COG0175	sulfate reduction
OCAR_RS15900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OCAR_RS15910	COG1376	ErfK ybiS ycfS ynhG family protein
OCAR_RS15915	COG0628	permease
OCAR_RS15935	COG0784	Response regulator, receiver
OCAR_RS15955	COG0513	Belongs to the DEAD box helicase family
OCAR_RS15960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OCAR_RS15965	COG1278	Cold shock
OCAR_RS15995	COG4964	Belongs to the GSP D family
OCAR_RS16030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OCAR_RS16035	COG0791	NLP P60 protein
OCAR_RS16040	COG4172	Belongs to the ABC transporter superfamily
OCAR_RS16045	COG4239	(ABC) transporter, permease
OCAR_RS16050	COG4174	ABC transporter (Permease)
OCAR_RS16055	COG4166	transmembrane transport
OCAR_RS16060	COG4166	transmembrane transport
OCAR_RS16065	COG3474	cytochrome
OCAR_RS16070	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OCAR_RS16080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OCAR_RS16085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OCAR_RS16100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OCAR_RS16105	COG0183	Belongs to the thiolase family
OCAR_RS16115	COG0582	viral genome integration into host DNA
OCAR_RS16195	COG1704	LemA family
OCAR_RS16200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OCAR_RS16235	COG0154	amidase activity
OCAR_RS16265	COG0583	DNA-binding transcription factor activity
OCAR_RS16300	COG1028	Short-chain dehydrogenase reductase Sdr
OCAR_RS16325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OCAR_RS16325	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OCAR_RS16340	COG1132	(ABC) transporter
OCAR_RS16345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OCAR_RS16350	COG4585	Histidine kinase
OCAR_RS16385	COG1414	Transcriptional regulator
OCAR_RS16405	COG5001	Diguanylate cyclase
OCAR_RS16415	COG2010	Cytochrome c
OCAR_RS16415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OCAR_RS16420	COG2080	2 iron, 2 sulfur cluster binding
OCAR_RS16430	COG4608	Belongs to the ABC transporter superfamily
OCAR_RS16435	COG0444	Belongs to the ABC transporter superfamily
OCAR_RS16445	COG0601	transmembrane transport
OCAR_RS16460	COG0154	amidase activity
OCAR_RS16470	COG2217	Heavy metal translocating P-type atpase
OCAR_RS16475	COG0789	Transcriptional regulator
OCAR_RS16485	COG0747	negative chemotaxis
OCAR_RS16505	COG3852	Histidine kinase
OCAR_RS16510	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OCAR_RS16515	COG0594	ribonuclease P activity
OCAR_RS16520	COG0706	membrane insertase activity
OCAR_RS16525	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OCAR_RS16535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OCAR_RS16545	COG2171	N-acyltransferase activity
OCAR_RS16550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OCAR_RS16560	COG0101	tRNA pseudouridine synthase activity
OCAR_RS16565	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OCAR_RS16570	COG0242	peptide deformylase activity
OCAR_RS16580	COG2223	nitrite transmembrane transporter activity
OCAR_RS16585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OCAR_RS16590	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OCAR_RS16595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OCAR_RS16605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCAR_RS16610	COG1522	sequence-specific DNA binding
OCAR_RS16625	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
OCAR_RS16630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OCAR_RS16660	COG2188	Transcriptional regulator
OCAR_RS16665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCAR_RS16680	COG1643	Atp-dependent helicase
OCAR_RS16685	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OCAR_RS16695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCAR_RS16695	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCAR_RS16700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OCAR_RS16720	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OCAR_RS16730	COG0745	RESPONSE REGULATOR receiver
OCAR_RS16735	COG0642	Histidine kinase
OCAR_RS16745	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCAR_RS16745	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCAR_RS16750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCAR_RS16755	COG0481	GTPase activity
OCAR_RS16765	COG3422	double-strand break repair
OCAR_RS16785	COG0725	ABC transporter, periplasmic molybdate-binding protein
OCAR_RS16790	COG4149	molybdate abc transporter
OCAR_RS16795	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OCAR_RS16805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCAR_RS16810	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OCAR_RS16815	COG3263	regulation of cellular component size
OCAR_RS16820	COG3264	Mechanosensitive ion channel
OCAR_RS16820	COG1511	domain protein
OCAR_RS16825	COG0024	Methionine aminopeptidase
OCAR_RS16830	COG2003	Belongs to the UPF0758 family
OCAR_RS16860	COG3701	Conjugal transfer protein
OCAR_RS16865	COG3846	protein secretion by the type IV secretion system
OCAR_RS16880	COG3451	type IV secretory pathway VirB4
OCAR_RS16895	COG4962	Type ii secretion system protein e
OCAR_RS16910	COG0583	DNA-binding transcription factor activity
OCAR_RS16915	COG1595	DNA-templated transcription, initiation
OCAR_RS16995	COG0456	acetyltransferase
OCAR_RS16995	COG1214	PFAM Peptidase M22, glycoprotease
OCAR_RS17040	COG1937	Protein conserved in bacteria
OCAR_RS17065	COG1192	Involved in chromosome partitioning
OCAR_RS17070	COG1414	Transcriptional regulator
OCAR_RS17085	COG0629	single-stranded DNA binding
OCAR_RS17090	COG1414	Transcriptional regulator
OCAR_RS17095	COG1475	DNA binding
OCAR_RS17100	COG1192	Involved in chromosome partitioning
OCAR_RS17135	COG0464	growth
OCAR_RS17195	COG5489	Protein of unknown function (DUF736)
OCAR_RS17355	COG3451	type IV secretory pathway VirB4
OCAR_RS17380	COG3704	protein secretion by the type IV secretion system
OCAR_RS17390	COG3504	Conjugal transfer protein
OCAR_RS17400	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
OCAR_RS17410	COG0697	spore germination
OCAR_RS17485	COG4786	Flagellar basal body rod
OCAR_RS17490	COG0672	)-iron permease
OCAR_RS17610	COG0798	PFAM Bile acid sodium symporter
OCAR_RS17620	COG0431	NADPH-dependent FMN reductase
OCAR_RS17625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCAR_RS17650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OCAR_RS17675	COG2217	Heavy metal translocating P-type atpase
OCAR_RS17735	COG1595	DNA-templated transcription, initiation
OCAR_RS17885	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OCAR_RS17970	COG5487	UPF0391 membrane protein
OCAR_RS18235	COG2197	response regulator