locus-tag	class	description
LIN98_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LIN98_RS00010	COG0592	DNA-directed DNA polymerase activity
LIN98_RS00020	COG2226	methyltransferase
LIN98_RS00035	COG2801	Transposase and inactivated derivatives
LIN98_RS00045	COG0281	malic enzyme
LIN98_RS00050	COG2081	HI0933 family
LIN98_RS00055	COG4235	cytochrome complex assembly
LIN98_RS00055	COG3088	subunit of a heme lyase
LIN98_RS00060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIN98_RS00065	COG1138	Cytochrome C-type biogenesis protein
LIN98_RS00070	COG3301	Polysulphide reductase, NrfD
LIN98_RS00075	COG0437	4 iron, 4 sulfur cluster binding
LIN98_RS00080	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
LIN98_RS00115	COG1138	Cytochrome C-type biogenesis protein
LIN98_RS00125	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LIN98_RS00130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LIN98_RS00135	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LIN98_RS00140	COG4133	protoheme IX ABC transporter activity
LIN98_RS00155	COG0280	phosphate acetyltransferase
LIN98_RS00155	COG0281	malic enzyme
LIN98_RS00170	COG2321	neutral zinc metallopeptidase
LIN98_RS00185	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LIN98_RS00190	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LIN98_RS00200	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LIN98_RS00215	COG0436	Aminotransferase
LIN98_RS00225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LIN98_RS00230	COG2267	carboxylic ester hydrolase activity
LIN98_RS00245	COG3091	SprT-like family
LIN98_RS00250	COG0814	amino acid
LIN98_RS00255	COG1760	l-serine dehydratase
LIN98_RS00260	COG0252	asparaginase activity
LIN98_RS00270	COG3063	Type IV pilus biogenesis stability protein PilW
LIN98_RS00275	COG1426	Protein conserved in bacteria
LIN98_RS00290	COG2976	Protein conserved in bacteria
LIN98_RS00300	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LIN98_RS00305	COG2233	PERMEase
LIN98_RS00310	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LIN98_RS00315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LIN98_RS00320	COG2918	glutathione biosynthetic process
LIN98_RS00320	COG1181	Belongs to the D-alanine--D-alanine ligase family
LIN98_RS00325	COG2194	sulfuric ester hydrolase activity
LIN98_RS00330	COG0740	serine-type endopeptidase activity
LIN98_RS00350	COG3739	integral membrane protein
LIN98_RS00355	COG2217	Heavy metal translocating P-type atpase
LIN98_RS00360	COG2608	mercury ion transmembrane transporter activity
LIN98_RS00365	COG0789	Transcriptional regulator
LIN98_RS00385	COG1720	tRNA m6t6A37 methyltransferase activity
LIN98_RS00390	COG1575	Belongs to the MenA family. Type 1 subfamily
LIN98_RS00400	COG0471	metal ion transport
LIN98_RS00405	COG3028	Belongs to the UPF0307 family
LIN98_RS00410	COG0312	modulator of DNA gyrase
LIN98_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LIN98_RS00420	COG1929	Belongs to the glycerate kinase type-1 family
LIN98_RS00425	COG2610	gluconate transmembrane transporter activity
LIN98_RS00430	COG3835	regulator
LIN98_RS00445	COG0513	Belongs to the DEAD box helicase family
LIN98_RS00450	COG4785	May be involved in cell division
LIN98_RS00460	COG2731	YhcH YjgK YiaL family protein
LIN98_RS00465	COG3023	N-Acetylmuramoyl-L-alanine amidase
LIN98_RS00470	COG4969	Belongs to the N-Me-Phe pilin family
LIN98_RS00480	COG1459	type II secretion system
LIN98_RS00490	COG0237	dephospho-CoA kinase activity
LIN98_RS00490	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LIN98_RS00495	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LIN98_RS00505	COG1115	amino acid carrier protein
LIN98_RS00510	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LIN98_RS00535	COG2184	nucleotidyltransferase activity
LIN98_RS00540	COG4145	pantothenate transmembrane transporter activity
LIN98_RS00545	COG3924	membrane
LIN98_RS00550	COG4783	chaperone-mediated protein folding
LIN98_RS00560	COG0439	Biotin carboxylase
LIN98_RS00565	COG0511	ligase activity, forming carbon-carbon bonds
LIN98_RS00590	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LIN98_RS00600	COG0456	acetyltransferase
LIN98_RS00605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LIN98_RS00615	COG3078	GTPase activator activity
LIN98_RS00620	COG0590	tRNA wobble adenosine to inosine editing
LIN98_RS00635	COG0730	response to heat
LIN98_RS00645	COG1869	D-ribose catabolic process
LIN98_RS00660	COG1879	ABC-type sugar transport system periplasmic component
LIN98_RS00665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LIN98_RS00670	COG1278	Cold shock
LIN98_RS00705	COG0165	Argininosuccinate lyase
LIN98_RS00710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LIN98_RS00715	COG0753	catalase activity
LIN98_RS00725	COG0587	DNA-directed DNA polymerase activity
LIN98_RS00730	COG1022	Amp-dependent synthetase and ligase
LIN98_RS00740	COG1328	CTP reductase activity
LIN98_RS00740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LIN98_RS00745	COG0602	queuosine metabolic process
LIN98_RS00750	COG0084	hydrolase, TatD family'
LIN98_RS00765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LIN98_RS00790	COG1686	Belongs to the peptidase S11 family
LIN98_RS00795	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LIN98_RS00795	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LIN98_RS00800	COG0772	Belongs to the SEDS family
LIN98_RS00805	COG0768	penicillin binding
LIN98_RS00815	COG0799	negative regulation of ribosome biogenesis
LIN98_RS00820	COG0513	Belongs to the DEAD box helicase family
LIN98_RS00825	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LIN98_RS00830	COG2814	Major facilitator Superfamily
LIN98_RS00840	COG1028	Short-chain dehydrogenase reductase Sdr
LIN98_RS00845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LIN98_RS00855	COG0416	fatty acid biosynthetic process
LIN98_RS00865	COG1399	metal-binding, possibly nucleic acid-binding protein
LIN98_RS00875	COG0500	methyltransferase
LIN98_RS00880	COG2830	Protein of unknown function (DUF452)
LIN98_RS00890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LIN98_RS00895	COG0688	phosphatidylethanolamine metabolic process
LIN98_RS00900	COG0545	Peptidyl-prolyl cis-trans isomerase
LIN98_RS00910	COG2966	Psort location CytoplasmicMembrane, score
LIN98_RS00915	COG3610	response to peptide
LIN98_RS00920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LIN98_RS00925	COG1253	flavin adenine dinucleotide binding
LIN98_RS00935	COG0084	hydrolase, TatD family'
LIN98_RS00940	COG0470	DNA polymerase III
LIN98_RS00945	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LIN98_RS00950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LIN98_RS00955	COG0347	Belongs to the P(II) protein family
LIN98_RS00960	COG1349	DNA-binding transcription factor activity
LIN98_RS00965	COG2084	Dehydrogenase
LIN98_RS00970	COG3395	kinase activity
LIN98_RS00975	COG0235	Class ii aldolase
LIN98_RS00980	COG3622	Belongs to the hyi family
LIN98_RS00985	COG2610	gluconate transmembrane transporter activity
LIN98_RS01000	COG0561	phosphatase activity
LIN98_RS01025	COG3085	chromosome segregation
LIN98_RS01030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LIN98_RS01035	COG3084	Protein conserved in bacteria
LIN98_RS01040	COG0746	molybdenum cofactor guanylyltransferase activity
LIN98_RS01050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIN98_RS01050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIN98_RS01055	COG1105	Belongs to the carbohydrate kinase PfkB family
LIN98_RS01060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LIN98_RS01060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LIN98_RS01060	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LIN98_RS01090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LIN98_RS01110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LIN98_RS01135	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LIN98_RS01140	COG0255	Belongs to the universal ribosomal protein uL29 family
LIN98_RS01145	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LIN98_RS01150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LIN98_RS01155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LIN98_RS01160	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LIN98_RS01165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LIN98_RS01170	COG0089	rRNA binding
LIN98_RS01175	COG0088	Forms part of the polypeptide exit tunnel
LIN98_RS01180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LIN98_RS01185	COG0051	transcription antitermination factor activity, RNA binding
LIN98_RS01190	COG0583	DNA-binding transcription factor activity
LIN98_RS01200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LIN98_RS01205	COG2031	fatty acid transporter
LIN98_RS01210	COG0183	Belongs to the thiolase family
LIN98_RS01220	COG1288	antiporter activity
LIN98_RS01225	COG0549	Belongs to the carbamate kinase family
LIN98_RS01230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LIN98_RS01235	COG0038	chloride channel
LIN98_RS01240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LIN98_RS01250	COG1522	sequence-specific DNA binding
LIN98_RS01255	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
LIN98_RS01265	COG1393	Belongs to the ArsC family
LIN98_RS01275	COG3036	rescue of stalled ribosome
LIN98_RS01280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LIN98_RS01285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LIN98_RS01290	COG2841	Protein conserved in bacteria
LIN98_RS01305	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LIN98_RS01315	COG0569	domain protein
LIN98_RS01320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LIN98_RS01320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LIN98_RS01365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LIN98_RS01385	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LIN98_RS01390	COG2990	Protein conserved in bacteria
LIN98_RS01420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LIN98_RS01440	COG3501	Rhs element vgr protein
LIN98_RS01445	COG3209	COG3209 Rhs family protein
LIN98_RS01525	COG2861	carbohydrate metabolic process
LIN98_RS01530	COG4942	peptidase
LIN98_RS01535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LIN98_RS01550	COG2853	Lipoprotein
LIN98_RS01555	COG0747	negative chemotaxis
LIN98_RS01580	COG0814	amino acid
LIN98_RS01590	COG4783	chaperone-mediated protein folding
LIN98_RS01595	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LIN98_RS01605	COG0552	protein localization to endoplasmic reticulum
LIN98_RS01610	COG0742	ribosomal rna small subunit methyltransferase
LIN98_RS01615	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIN98_RS01615	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIN98_RS01620	COG3715	PTS system
LIN98_RS01625	COG3716	PTS system mannose fructose sorbose family IID component
LIN98_RS01630	COG0561	phosphatase activity
LIN98_RS01635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIN98_RS01650	COG1649	PFAM Uncharacterised BCR, COG1649
LIN98_RS01650	COG0726	polysaccharide deacetylase
LIN98_RS01655	COG1215	transferase activity, transferring glycosyl groups
LIN98_RS01665	COG2271	Major facilitator Superfamily
LIN98_RS01695	COG0513	Belongs to the DEAD box helicase family
LIN98_RS01705	COG3201	nicotinamide mononucleotide transporter
LIN98_RS01725	COG1238	metal cluster binding
LIN98_RS01730	COG0110	maltose O-acetyltransferase activity
LIN98_RS01735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LIN98_RS01760	COG0210	DNA helicase
LIN98_RS01765	COG5645	(Lipo)protein
LIN98_RS01775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LIN98_RS01775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LIN98_RS01790	COG0737	Belongs to the 5'-nucleotidase family
LIN98_RS01800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIN98_RS01810	COG0859	PFAM glycosyl transferase family 9
LIN98_RS01815	COG0754	glutathionylspermidine amidase activity
LIN98_RS01820	COG3005	denitrification pathway
LIN98_RS01825	COG3043	anaerobic respiration
LIN98_RS01830	COG0348	domain, Protein
LIN98_RS01835	COG0437	4 iron, 4 sulfur cluster binding
LIN98_RS01840	COG0243	molybdopterin cofactor binding
LIN98_RS01845	COG3062	negative regulation of establishment of protein localization
LIN98_RS01850	COG3850	Histidine kinase
LIN98_RS01855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LIN98_RS01865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LIN98_RS01870	COG3070	regulator of competence-specific genes
LIN98_RS01875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LIN98_RS01890	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LIN98_RS01900	COG0583	DNA-binding transcription factor activity
LIN98_RS01905	COG2962	Rard protein
LIN98_RS01920	COG0551	DNA topoisomerase type I activity
LIN98_RS01945	COG0705	Rhomboid family
LIN98_RS01950	COG1349	DNA-binding transcription factor activity
LIN98_RS01960	COG4178	(ABC) transporter
LIN98_RS01975	COG0233	cytoplasmic translational termination
LIN98_RS01990	COG0575	Belongs to the CDS family
LIN98_RS02005	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LIN98_RS02025	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LIN98_RS02035	COG0490	domain, Protein
LIN98_RS02035	COG0471	metal ion transport
LIN98_RS02040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LIN98_RS02055	COG0521	Mo-molybdopterin cofactor biosynthetic process
LIN98_RS02080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LIN98_RS02090	COG0251	oxidation-reduction process
LIN98_RS02095	COG2137	regulation of response to DNA damage stimulus
LIN98_RS02100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LIN98_RS02110	COG2095	MarC family integral membrane protein
LIN98_RS02130	COG0582	viral genome integration into host DNA
LIN98_RS02175	COG3561	AntA/AntB antirepressor
LIN98_RS02210	COG1349	DNA-binding transcription factor activity
LIN98_RS02220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LIN98_RS02230	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LIN98_RS02255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIN98_RS02260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIN98_RS02265	COG0765	amino acid transport
LIN98_RS02270	COG1126	abc transporter atp-binding protein
LIN98_RS02275	COG2168	tRNA wobble position uridine thiolation
LIN98_RS02285	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LIN98_RS02290	COG2964	Protein conserved in bacteria
LIN98_RS02295	COG0545	Peptidyl-prolyl cis-trans isomerase
LIN98_RS02300	COG2900	Belongs to the SlyX family
LIN98_RS02305	COG0678	peroxiredoxin activity
LIN98_RS02305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LIN98_RS02310	COG0583	DNA-binding transcription factor activity
LIN98_RS02315	COG1309	transcriptional regulator
LIN98_RS02320	COG1132	(ABC) transporter
LIN98_RS02325	COG4988	ABC transporter
LIN98_RS02330	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LIN98_RS02335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIN98_RS02340	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LIN98_RS02350	COG1045	serine acetyltransferase
LIN98_RS02355	COG1494	fructose-1,6-bisphosphatase
LIN98_RS02365	COG0716	FMN binding
LIN98_RS02375	COG0702	epimerase
LIN98_RS02380	COG1733	regulation of RNA biosynthetic process
LIN98_RS02390	COG3312	ion transport
LIN98_RS02410	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LIN98_RS02420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LIN98_RS02435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LIN98_RS02445	COG3716	PTS system mannose fructose sorbose family IID component
LIN98_RS02450	COG3715	PTS system
LIN98_RS02455	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIN98_RS02455	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIN98_RS02460	COG2814	Major facilitator Superfamily
LIN98_RS02465	COG2207	Transcriptional regulator
LIN98_RS02465	COG1609	Transcriptional regulator
LIN98_RS02470	COG1757	Na H antiporter
LIN98_RS02475	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LIN98_RS02480	COG4214	carbohydrate transport
LIN98_RS02485	COG1129	ABC transporter
LIN98_RS02490	COG4213	ABC transporter substrate-binding protein
LIN98_RS02495	COG2115	Belongs to the xylose isomerase family
LIN98_RS02500	COG1070	Carbohydrate kinase
LIN98_RS02520	COG2801	Transposase and inactivated derivatives
LIN98_RS02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIN98_RS02530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LIN98_RS02535	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LIN98_RS02540	COG3719	Belongs to the RNase T2 family
LIN98_RS02550	COG0191	fructose-bisphosphate aldolase activity
LIN98_RS02555	COG3307	-O-antigen
LIN98_RS02560	COG2267	carboxylic ester hydrolase activity
LIN98_RS02565	COG0561	phosphatase activity
LIN98_RS02580	COG2177	Part of the ABC transporter FtsEX involved in
LIN98_RS02585	COG2884	Cell division ATP-binding protein ftsE
LIN98_RS02595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LIN98_RS02625	COG1238	metal cluster binding
LIN98_RS02635	COG1388	LysM domain
LIN98_RS02635	COG4942	peptidase
LIN98_RS02645	COG0463	Glycosyl transferase, family 2
LIN98_RS02650	COG1519	Transferase
LIN98_RS02665	COG0859	PFAM glycosyl transferase family 9
LIN98_RS02670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LIN98_RS02675	COG1917	Cupin 2, conserved barrel domain protein
LIN98_RS02675	COG4977	sequence-specific DNA binding
LIN98_RS02680	COG1132	(ABC) transporter
LIN98_RS02715	COG0758	DNA mediated transformation
LIN98_RS02720	COG0584	glycerophosphoryl diester phosphodiesterase
LIN98_RS02725	COG2271	Major facilitator Superfamily
LIN98_RS02735	COG0557	exoribonuclease II activity
LIN98_RS02740	COG1077	Cell shape determining protein MreB Mrl
LIN98_RS02745	COG1792	Involved in formation and maintenance of cell shape
LIN98_RS02750	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LIN98_RS02775	COG0006	proline dipeptidase activity
LIN98_RS02795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LIN98_RS02810	COG1496	oxidoreductase activity
LIN98_RS02820	COG0778	Nitroreductase
LIN98_RS02830	COG0762	integral membrane protein
LIN98_RS02840	COG0500	methyltransferase
LIN98_RS02845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LIN98_RS02850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LIN98_RS02855	COG1309	transcriptional regulator
LIN98_RS02860	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LIN98_RS02865	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LIN98_RS02880	COG3306	glycosyltransferase involved in LPS biosynthesis
LIN98_RS02890	COG3306	glycosyltransferase involved in LPS biosynthesis
LIN98_RS02925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LIN98_RS02935	COG1309	transcriptional regulator
LIN98_RS02950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LIN98_RS02955	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LIN98_RS02960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LIN98_RS02965	COG4972	Pilus assembly protein
LIN98_RS02985	COG4796	Type ii and iii secretion system protein
LIN98_RS03000	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LIN98_RS03010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LIN98_RS03020	COG2801	Transposase and inactivated derivatives
LIN98_RS03025	COG0789	Transcriptional regulator
LIN98_RS03030	COG4701	Protein of unknown function (DUF721)
LIN98_RS03045	COG0494	nUDIX hydrolase
LIN98_RS03050	COG1466	dna polymerase III delta subunit
LIN98_RS03055	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LIN98_RS03070	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
LIN98_RS03075	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
LIN98_RS03080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LIN98_RS03085	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LIN98_RS03090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LIN98_RS03110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LIN98_RS03120	COG4221	oxidoreductase activity
LIN98_RS03130	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LIN98_RS03135	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LIN98_RS03140	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LIN98_RS03145	COG4137	Cytochrome C assembly protein
LIN98_RS03150	COG4536	flavin adenine dinucleotide binding
LIN98_RS03155	COG0811	peptide transport
LIN98_RS03160	COG0848	biopolymer transport protein
LIN98_RS03175	COG0243	molybdopterin cofactor binding
LIN98_RS03180	COG0437	4 iron, 4 sulfur cluster binding
LIN98_RS03185	COG3302	dmso reductase anchor subunit
LIN98_RS03190	COG3381	protein complex oligomerization
LIN98_RS03195	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LIN98_RS03195	COG2221	Nitrite and sulphite reductase 4Fe-4S
LIN98_RS03205	COG4545	Glutaredoxin-related protein
LIN98_RS03230	COG0805	protein transport
LIN98_RS03235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LIN98_RS03240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LIN98_RS03245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LIN98_RS03250	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LIN98_RS03255	COG1011	Hydrolase
LIN98_RS03260	COG0494	nUDIX hydrolase
LIN98_RS03280	COG3059	membrane
LIN98_RS03285	COG1297	OPT oligopeptide transporter protein
LIN98_RS03295	COG1218	3'(2'),5'-bisphosphate nucleotidase
LIN98_RS03300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LIN98_RS03305	COG0363	glucosamine-6-phosphate deaminase activity
LIN98_RS03315	COG1794	racemase activity, acting on amino acids and derivatives
LIN98_RS03320	COG4545	Glutaredoxin-related protein
LIN98_RS03335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LIN98_RS03340	COG1028	Short-chain dehydrogenase reductase Sdr
LIN98_RS03350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LIN98_RS03405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LIN98_RS03430	COG1011	Hydrolase
LIN98_RS03440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LIN98_RS03445	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LIN98_RS03465	COG1596	polysaccharide export
LIN98_RS03465	COG1555	photosystem II stabilization
LIN98_RS03470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LIN98_RS03475	COG0561	phosphatase activity
LIN98_RS03480	COG1040	competence protein
LIN98_RS03495	COG1114	Component of the transport system for branched-chain amino acids
LIN98_RS03520	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LIN98_RS03530	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LIN98_RS03540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LIN98_RS03560	COG0201	protein transport
LIN98_RS03580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LIN98_RS03600	COG0814	amino acid
LIN98_RS03605	COG2129	metallophosphoesterase
LIN98_RS03610	COG3172	ATPase kinase involved in NAD metabolism
LIN98_RS03630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LIN98_RS03635	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LIN98_RS03665	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LIN98_RS03675	COG2801	Transposase and inactivated derivatives
LIN98_RS03685	COG2364	Membrane
LIN98_RS03695	COG0859	PFAM glycosyl transferase family 9
LIN98_RS03700	COG1027	Aspartate ammonia-lyase
LIN98_RS03710	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LIN98_RS03715	COG0459	protein refolding
LIN98_RS03735	COG2801	Transposase and inactivated derivatives
LIN98_RS03745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LIN98_RS03750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LIN98_RS03755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LIN98_RS03760	COG1381	Involved in DNA repair and RecF pathway recombination
LIN98_RS03765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LIN98_RS03780	COG0354	folic acid binding
LIN98_RS03785	COG1561	YicC-like family, N-terminal region
LIN98_RS03795	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LIN98_RS03810	COG3842	ATPase activity
LIN98_RS03815	COG1178	ABC-type Fe3 transport system permease component
LIN98_RS03820	COG1840	ABC-type Fe3 transport system, periplasmic component
LIN98_RS03825	COG3171	Protein conserved in bacteria
LIN98_RS03835	COG1194	a g-specific adenine glycosylase
LIN98_RS03860	COG3056	Lipoprotein
LIN98_RS03865	COG0271	Belongs to the BolA IbaG family
LIN98_RS03880	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LIN98_RS03885	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LIN98_RS03890	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LIN98_RS03895	COG2871	sodium ion transport
LIN98_RS03900	COG1477	protein flavinylation
LIN98_RS03905	COG2991	Protein conserved in bacteria
LIN98_RS03915	COG0148	phosphopyruvate hydratase activity
LIN98_RS03930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LIN98_RS03935	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LIN98_RS03940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LIN98_RS03945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LIN98_RS03950	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LIN98_RS03965	COG3956	TIGRFAM MazG family protein
LIN98_RS03970	COG0402	S-adenosylhomocysteine deaminase activity
LIN98_RS03975	COG3083	sulfuric ester hydrolase activity
LIN98_RS03980	COG3082	Protein of unknown function (DUF1414)
LIN98_RS03990	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LIN98_RS03995	COG0745	RESPONSE REGULATOR receiver
LIN98_RS04000	COG2205	protein histidine kinase activity
LIN98_RS04005	COG0786	glutamate:sodium symporter activity
LIN98_RS04025	COG2258	MOSC domain
LIN98_RS04030	COG0433	COG0433 Predicted ATPase
LIN98_RS04045	COG0656	L-ascorbic acid biosynthetic process
LIN98_RS04050	COG0667	Aldo Keto reductase
LIN98_RS04055	COG2272	Belongs to the type-B carboxylesterase lipase family
LIN98_RS04085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LIN98_RS04090	COG1349	DNA-binding transcription factor activity
LIN98_RS04100	COG3068	Protein conserved in bacteria
LIN98_RS04105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LIN98_RS04125	COG0248	Ppx GppA phosphatase
LIN98_RS04130	COG2911	Protein conserved in bacteria
LIN98_RS04135	COG0729	surface antigen
LIN98_RS04140	COG2197	response regulator
LIN98_RS04150	COG0181	hydroxymethylbilane synthase activity
LIN98_RS04160	COG2959	enzyme of heme biosynthesis
LIN98_RS04165	COG3071	HemY protein
LIN98_RS04170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LIN98_RS04180	COG1595	DNA-templated transcription, initiation
LIN98_RS04190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LIN98_RS04210	COG0583	DNA-binding transcription factor activity
LIN98_RS04215	COG2183	response to ionizing radiation
LIN98_RS04225	COG1172	Belongs to the binding-protein-dependent transport system permease family
LIN98_RS04230	COG1129	ABC transporter
LIN98_RS04235	COG1879	ABC-type sugar transport system periplasmic component
LIN98_RS04240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LIN98_RS04265	COG1072	(Pantothenic acid kinase))
LIN98_RS04270	COG0187	DNA topoisomerase II activity
LIN98_RS04275	COG0514	ATP-dependent DNA helicase (RecQ)
LIN98_RS04290	COG0019	diaminopimelate decarboxylase activity
LIN98_RS04295	COG3477	response to acidic pH
LIN98_RS04300	COG2818	Glycosylase
LIN98_RS04305	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LIN98_RS04315	COG2195	Cleaves the N-terminal amino acid of tripeptides
LIN98_RS04320	COG0300	oxidoreductase activity
LIN98_RS04325	COG1763	Mo-molybdopterin cofactor biosynthetic process
LIN98_RS04330	COG3086	response to oxidative stress
LIN98_RS04335	COG3026	antisigma factor binding
LIN98_RS04340	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LIN98_RS04345	COG1595	DNA-templated transcription, initiation
LIN98_RS04360	COG0442	prolyl-tRNA aminoacylation
LIN98_RS04365	COG1921	L-seryl-tRNASec selenium transferase activity
LIN98_RS04370	COG3276	selenocysteine insertion sequence binding
LIN98_RS04380	COG1285	pathogenesis
LIN98_RS04390	COG0733	neurotransmitter:sodium symporter activity
LIN98_RS04455	COG4964	Belongs to the GSP D family
LIN98_RS04480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LIN98_RS04490	COG1444	tRNA N-acetyltransferase activity
LIN98_RS04500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LIN98_RS04510	COG1126	abc transporter atp-binding protein
LIN98_RS04515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIN98_RS04520	COG4215	(ABC) transporter
LIN98_RS04525	COG4160	amino acid transport
LIN98_RS04530	COG1966	Carbon starvation protein
LIN98_RS04545	COG3116	cell division
LIN98_RS04550	COG0768	penicillin binding
LIN98_RS04560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LIN98_RS04570	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LIN98_RS04580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LIN98_RS04595	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LIN98_RS04600	COG0849	cell division
LIN98_RS04605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LIN98_RS04615	COG1605	Chorismate mutase
LIN98_RS04615	COG0077	Prephenate dehydratase
LIN98_RS04620	COG0326	Molecular chaperone. Has ATPase activity
LIN98_RS04625	COG1393	Belongs to the ArsC family
LIN98_RS04635	COG1876	peptidase activity
LIN98_RS04640	COG0494	nUDIX hydrolase
LIN98_RS04645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LIN98_RS04690	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LIN98_RS04700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LIN98_RS04705	COG1053	succinate dehydrogenase
LIN98_RS04715	COG1120	ATPase activity
LIN98_RS04720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIN98_RS04725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIN98_RS04730	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LIN98_RS04735	COG1408	metallophosphoesterase
LIN98_RS04745	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LIN98_RS04750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LIN98_RS04770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIN98_RS04780	COG0741	lytic transglycosylase activity
LIN98_RS04785	COG2350	Protein conserved in bacteria
LIN98_RS04790	COG1607	acyl-coa hydrolase
LIN98_RS04805	COG3047	cAMP biosynthetic process
LIN98_RS04810	COG0497	DNA recombination
LIN98_RS04820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LIN98_RS04830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIN98_RS04830	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LIN98_RS04835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LIN98_RS04840	COG2198	Histidine kinase
LIN98_RS04840	COG5002	protein histidine kinase activity
LIN98_RS04840	COG0784	Response regulator, receiver
LIN98_RS04845	COG4211	Belongs to the binding-protein-dependent transport system permease family
LIN98_RS04855	COG1879	ABC-type sugar transport system periplasmic component
LIN98_RS04860	COG1609	Transcriptional regulator
LIN98_RS04865	COG1085	galactose-1-phosphate uridylyltransferase
LIN98_RS04870	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LIN98_RS04875	COG2017	converts alpha-aldose to the beta-anomer
LIN98_RS04895	COG0471	metal ion transport
LIN98_RS04900	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LIN98_RS04900	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LIN98_RS04905	COG3051	citrate lyase alpha subunit
LIN98_RS04910	COG2301	Belongs to the HpcH HpaI aldolase family
LIN98_RS04920	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LIN98_RS04925	COG4535	Mg2 and Co2 transporter CorC
LIN98_RS04945	COG0105	UTP biosynthetic process
LIN98_RS04955	COG0489	protein tyrosine kinase activity
LIN98_RS04960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LIN98_RS04960	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LIN98_RS04965	COG2975	iron-sulfur cluster assembly
LIN98_RS04970	COG0633	Ferredoxin
LIN98_RS04975	COG0443	Heat shock 70 kDa protein
LIN98_RS04990	COG0822	iron-sulfur transferase activity
LIN98_RS05000	COG1959	2 iron, 2 sulfur cluster binding
LIN98_RS05005	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LIN98_RS05030	COG1840	ABC-type Fe3 transport system, periplasmic component
LIN98_RS05035	COG1840	ABC-type Fe3 transport system, periplasmic component
LIN98_RS05085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LIN98_RS05090	COG1530	ribonuclease E activity
LIN98_RS05095	COG2999	glutathione oxidoreductase activity
LIN98_RS05100	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LIN98_RS05150	COG3021	interspecies interaction between organisms
LIN98_RS05185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LIN98_RS05190	COG0626	cystathionine gamma-synthase activity
LIN98_RS05205	COG2337	Toxic component of a toxin-antitoxin (TA) module
LIN98_RS05210	COG0484	heat shock protein binding
LIN98_RS05215	COG0443	Heat shock 70 kDa protein
LIN98_RS05220	COG5339	Protein conserved in bacteria
LIN98_RS05230	COG3102	Protein conserved in bacteria
LIN98_RS05235	COG3133	Outer membrane lipoprotein
LIN98_RS05240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LIN98_RS05245	COG2890	protein-(glutamine-N5) methyltransferase activity
LIN98_RS05255	COG0791	NLP P60 protein
LIN98_RS05260	COG3100	YcgL domain-containing protein
LIN98_RS05275	COG2062	phosphohistidine phosphatase, SixA
LIN98_RS05285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LIN98_RS05290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LIN98_RS05305	COG0529	Catalyzes the synthesis of activated sulfate
LIN98_RS05325	COG0517	IMP dehydrogenase activity
LIN98_RS05325	COG0516	GMP reductase activity
LIN98_RS05330	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LIN98_RS05330	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LIN98_RS05375	COG2801	Transposase and inactivated derivatives
LIN98_RS05380	COG0193	aminoacyl-tRNA hydrolase activity
LIN98_RS05385	COG0012	GTP binding
LIN98_RS05390	COG1573	uracil-dna glycosylase
LIN98_RS05395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LIN98_RS05405	COG3115	cell septum assembly
LIN98_RS05425	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LIN98_RS05430	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LIN98_RS05445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LIN98_RS05455	COG0659	secondary active sulfate transmembrane transporter activity
LIN98_RS05475	COG2186	Transcriptional regulator
LIN98_RS05490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LIN98_RS05500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LIN98_RS05505	COG1028	Short-chain dehydrogenase reductase Sdr
LIN98_RS05515	COG0800	Aldolase
LIN98_RS05520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIN98_RS05525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LIN98_RS05530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LIN98_RS05535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LIN98_RS05545	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LIN98_RS05550	COG1555	photosystem II stabilization
LIN98_RS05555	COG0330	HflC and HflK could
LIN98_RS05560	COG0330	HflC and HflK could
LIN98_RS05565	COG2091	lysine biosynthetic process via aminoadipic acid
LIN98_RS05570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LIN98_RS05585	COG0527	aspartate kinase activity
LIN98_RS05585	COG0460	homoserine dehydrogenase
LIN98_RS05595	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LIN98_RS05600	COG1125	glycine betaine transport
LIN98_RS05600	COG0517	IMP dehydrogenase activity
LIN98_RS05615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LIN98_RS05620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LIN98_RS05630	COG1217	gtp-binding protein TYPA
LIN98_RS05640	COG2801	Transposase and inactivated derivatives
LIN98_RS05650	COG0861	Integral membrane protein TerC family
LIN98_RS05660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LIN98_RS05665	COG2067	long-chain fatty acid transport protein
LIN98_RS05670	COG3691	Protein conserved in bacteria
LIN98_RS05680	COG0463	Glycosyl transferase, family 2
LIN98_RS05700	COG5007	Belongs to the BolA IbaG family
LIN98_RS05705	COG3113	response to antibiotic
LIN98_RS05710	COG2854	intermembrane phospholipid transfer
LIN98_RS05715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LIN98_RS05720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LIN98_RS05725	COG1127	ABC transporter
LIN98_RS05730	COG3117	lipopolysaccharide transmembrane transporter activity
LIN98_RS05735	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LIN98_RS05740	COG1137	ATPase activity
LIN98_RS05745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIN98_RS05760	COG2850	peptidyl-arginine hydroxylation
LIN98_RS05770	COG2867	negative regulation of translational initiation
LIN98_RS05780	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LIN98_RS05790	COG1758	RNA polymerase activity
LIN98_RS05795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LIN98_RS05805	COG3161	chorismate lyase activity
LIN98_RS05835	COG1757	Na H antiporter
LIN98_RS05840	COG2916	Histone family protein nucleoid-structuring protein H-NS
LIN98_RS05845	COG0788	formyltetrahydrofolate deformylase activity
LIN98_RS05855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LIN98_RS05905	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LIN98_RS05905	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LIN98_RS05910	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
LIN98_RS05915	COG3098	single-species biofilm formation
LIN98_RS05925	COG3140	Belongs to the UPF0181 family
LIN98_RS05930	COG1278	Cold shock
LIN98_RS05940	COG1067	ATP-dependent peptidase activity
LIN98_RS05945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LIN98_RS05955	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LIN98_RS05960	COG1074	ATP-dependent DNA helicase activity
LIN98_RS05965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LIN98_RS05985	COG0101	tRNA pseudouridine synthase activity
LIN98_RS06000	COG0471	metal ion transport
LIN98_RS06005	COG2315	Protein conserved in bacteria
LIN98_RS06010	COG0243	molybdopterin cofactor binding
LIN98_RS06015	COG3005	denitrification pathway
LIN98_RS06040	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LIN98_RS06050	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LIN98_RS06055	COG0314	molybdopterin synthase activity
LIN98_RS06065	COG2969	positive regulation of protein catabolic process
LIN98_RS06075	COG1940	carbohydrate kinase activity
LIN98_RS06080	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LIN98_RS06090	COG2390	Transcriptional regulator
LIN98_RS06100	COG1172	Belongs to the binding-protein-dependent transport system permease family
LIN98_RS06110	COG1879	ABC-type sugar transport system periplasmic component
LIN98_RS06185	COG0469	pyruvate kinase activity
LIN98_RS06195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LIN98_RS06205	COG0133	tryptophan synthase activity
LIN98_RS06210	COG4221	oxidoreductase activity
LIN98_RS06230	COG3630	sodium ion export across plasma membrane
LIN98_RS06245	COG0298	carbon dioxide binding
LIN98_RS06250	COG0134	indole-3-glycerol-phosphate synthase activity
LIN98_RS06250	COG0135	phosphoribosylanthranilate isomerase activity
LIN98_RS06255	COG3093	addiction module antidote protein HigA
LIN98_RS06265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LIN98_RS06270	COG1942	4-Oxalocrotonate Tautomerase
LIN98_RS06275	COG0512	Glutamine amidotransferase of anthranilate synthase
LIN98_RS06280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LIN98_RS06285	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LIN98_RS06290	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LIN98_RS06290	COG0517	IMP dehydrogenase activity
LIN98_RS06305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LIN98_RS06320	COG0791	NLP P60 protein
LIN98_RS06335	COG4774	siderophore transport
LIN98_RS06345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIN98_RS06350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIN98_RS06355	COG1120	ATPase activity
LIN98_RS06370	COG3585	molybdate ion transport
LIN98_RS06375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIN98_RS06380	COG1120	ATPase activity
LIN98_RS06385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIN98_RS06395	COG0842	Transport permease protein
LIN98_RS06400	COG1129	ABC transporter
LIN98_RS06400	COG0842	Transport permease protein
LIN98_RS06405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LIN98_RS06415	COG1448	Aminotransferase
LIN98_RS06420	COG0308	aminopeptidase N
LIN98_RS06425	COG0167	dihydroorotate dehydrogenase activity
LIN98_RS06430	COG0613	PHP domain protein
LIN98_RS06440	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
LIN98_RS06445	COG0589	response to stress
LIN98_RS06450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LIN98_RS06460	COG1528	Iron-storage protein
LIN98_RS06465	COG1528	Iron-storage protein
LIN98_RS06475	COG2801	Transposase and inactivated derivatives
LIN98_RS06485	COG2925	Exonuclease
LIN98_RS06490	COG0697	spore germination
LIN98_RS06495	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LIN98_RS06500	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LIN98_RS06505	COG0204	Acyl-transferase
LIN98_RS06505	COG0318	PFAM AMP-dependent synthetase and ligase
LIN98_RS06515	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LIN98_RS06520	COG1686	Belongs to the peptidase S11 family
LIN98_RS06530	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LIN98_RS06535	COG0586	Pfam SNARE associated Golgi protein
LIN98_RS06540	COG0058	SHG alpha-glucan phosphorylase activity
LIN98_RS06555	COG1523	belongs to the glycosyl hydrolase 13 family
LIN98_RS06580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LIN98_RS06585	COG1136	(ABC) transporter
LIN98_RS06585	COG0577	efflux transmembrane transporter activity
LIN98_RS06590	COG1538	Outer membrane efflux protein
LIN98_RS06615	COG2824	Alkylphosphonate utilization operon protein PhnA
LIN98_RS06625	COG0564	pseudouridine synthase activity
LIN98_RS06630	COG2431	L-lysine efflux transmembrane transporter activity
LIN98_RS06635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIN98_RS06640	COG0406	alpha-ribazole phosphatase activity
LIN98_RS06645	COG0285	dihydrofolate synthase activity
LIN98_RS06660	COG0142	geranyltranstransferase activity
LIN98_RS06670	COG1349	DNA-binding transcription factor activity
LIN98_RS06675	COG1063	alcohol dehydrogenase
LIN98_RS06680	COG3775	system Galactitol-specific IIC component
LIN98_RS06690	COG3684	Belongs to the aldolase LacD family
LIN98_RS06705	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LIN98_RS06710	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LIN98_RS06745	COG2885	chlorophyll binding
LIN98_RS06745	COG3047	cAMP biosynthetic process
LIN98_RS06750	COG0616	signal peptide processing
LIN98_RS06760	COG1252	NADH dehydrogenase
LIN98_RS06770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LIN98_RS06785	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LIN98_RS06790	COG2823	Periplasmic or secreted lipoprotein
LIN98_RS06795	COG0288	reversible hydration of carbon dioxide
LIN98_RS06800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LIN98_RS06800	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LIN98_RS06805	COG0785	Cytochrome C biogenesis protein
LIN98_RS06810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIN98_RS06830	COG2949	membrane
LIN98_RS06835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LIN98_RS06845	COG3099	Belongs to the UPF0263 family
LIN98_RS06855	COG0583	DNA-binding transcription factor activity
LIN98_RS06865	COG0009	L-threonylcarbamoyladenylate synthase
LIN98_RS06875	COG0616	signal peptide processing
LIN98_RS06880	COG0778	Nitroreductase
LIN98_RS06885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LIN98_RS06890	COG0508	dehydrogenase complex catalyzes the overall conversion of
LIN98_RS06895	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LIN98_RS06905	COG2909	trisaccharide binding
LIN98_RS06910	COG0058	SHG alpha-glucan phosphorylase activity
LIN98_RS06915	COG1640	4-alpha-glucanotransferase
LIN98_RS06920	COG1286	toxin biosynthetic process
LIN98_RS06925	COG3092	negative regulation of chromosome organization
LIN98_RS06930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LIN98_RS06935	COG0280	phosphate acetyltransferase
LIN98_RS06935	COG0857	belongs to the CobB CobQ family
LIN98_RS06945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LIN98_RS06950	COG0617	tRNA 3'-terminal CCA addition
LIN98_RS06955	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LIN98_RS06960	COG2333	competence protein COMEC
LIN98_RS06960	COG0658	competence protein
LIN98_RS06965	COG1132	(ABC) transporter
LIN98_RS06970	COG1663	tetraacyldisaccharide 4'-kinase activity
LIN98_RS06975	COG2835	tetraacyldisaccharide 4'-kinase activity
LIN98_RS06985	COG0322	excinuclease ABC activity
LIN98_RS06995	COG0395	ABC-type sugar transport system, permease component
LIN98_RS07000	COG1175	transmembrane transport
LIN98_RS07015	COG3177	Filamentation induced by cAMP protein fic
LIN98_RS07025	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LIN98_RS07030	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LIN98_RS07055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LIN98_RS07080	COG0195	Participates in both transcription termination and antitermination
LIN98_RS07095	COG3069	C4-dicarboxylate transmembrane transporter activity
LIN98_RS07100	COG3077	Addiction module antitoxin, RelB DinJ family
LIN98_RS07105	COG3041	Addiction module toxin RelE StbE family
LIN98_RS07115	COG0582	viral genome integration into host DNA
LIN98_RS07125	COG5301	cellulose 1,4-beta-cellobiosidase activity
LIN98_RS07135	COG1598	PFAM Uncharacterised protein family UPF0150
LIN98_RS07185	COG2351	hydroxyisourate hydrolase activity
LIN98_RS07190	COG0825	malonyl-CoA metabolic process
LIN98_RS07205	COG2252	PERMEase
LIN98_RS07210	COG3152	Membrane
LIN98_RS07215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LIN98_RS07220	COG0375	protein maturation
LIN98_RS07225	COG2814	Major facilitator Superfamily
LIN98_RS07230	COG0563	adenylate kinase activity
LIN98_RS07255	COG1940	carbohydrate kinase activity
LIN98_RS07255	COG1846	Transcriptional regulator
LIN98_RS07265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIN98_RS07280	COG3422	double-strand break repair
LIN98_RS07290	COG1944	ATP diphosphatase activity
LIN98_RS07295	COG3105	Protein conserved in bacteria
LIN98_RS07300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LIN98_RS07310	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LIN98_RS07315	COG1178	ABC-type Fe3 transport system permease component
LIN98_RS07320	COG4143	(ABC) transporter
LIN98_RS07335	COG1518	maintenance of DNA repeat elements
LIN98_RS07340	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LIN98_RS07375	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LIN98_RS07380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LIN98_RS07385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIN98_RS07400	COG0405	Gamma-glutamyltransferase
LIN98_RS07405	COG0642	Histidine kinase
LIN98_RS07420	COG3392	D12 class N6 adenine-specific DNA methyltransferase
LIN98_RS07445	COG3111	PFAM Bacterial OB fold (BOF) protein
LIN98_RS07455	COG0737	Belongs to the 5'-nucleotidase family
LIN98_RS07460	COG4607	ABC-type enterochelin transport system periplasmic component
LIN98_RS07465	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIN98_RS07470	COG4605	iron ion homeostasis
LIN98_RS07475	COG4604	ABC transporter, ATP-binding protein
LIN98_RS07480	COG0739	heme binding
LIN98_RS07490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LIN98_RS07495	COG0733	neurotransmitter:sodium symporter activity
LIN98_RS07500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LIN98_RS07530	COG4657	Part of a membrane complex involved in electron transport
LIN98_RS07535	COG1090	epimerase
LIN98_RS07540	COG1438	arginine binding
LIN98_RS07545	COG0039	L-malate dehydrogenase activity
LIN98_RS07555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LIN98_RS07560	COG0583	DNA-binding transcription factor activity
LIN98_RS07570	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LIN98_RS07575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LIN98_RS07575	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LIN98_RS07580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LIN98_RS07590	COG0471	metal ion transport
LIN98_RS07595	COG2005	Transcriptional regulator
LIN98_RS07600	COG0725	ABC transporter, periplasmic molybdate-binding protein
LIN98_RS07605	COG4149	molybdate abc transporter
LIN98_RS07610	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LIN98_RS07615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LIN98_RS07620	COG0795	lipopolysaccharide-transporting ATPase activity
LIN98_RS07625	COG0795	lipopolysaccharide-transporting ATPase activity
LIN98_RS07630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LIN98_RS07635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LIN98_RS07645	COG0309	Hydrogenase expression formation protein (HypE)
LIN98_RS07650	COG0409	Hydrogenase expression formation protein
LIN98_RS07655	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LIN98_RS07665	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LIN98_RS07670	COG0310	cobalt ion transport
LIN98_RS07675	COG0310	cobalt ion transport
LIN98_RS07680	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
LIN98_RS07685	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LIN98_RS07690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LIN98_RS07695	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LIN98_RS07700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LIN98_RS07710	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LIN98_RS07715	COG0720	synthase
LIN98_RS07720	COG0602	queuosine metabolic process
LIN98_RS07725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LIN98_RS07730	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LIN98_RS07740	COG0783	Belongs to the Dps family
LIN98_RS07745	COG1566	PFAM secretion protein HlyD family protein
LIN98_RS07750	COG2814	Major facilitator Superfamily
LIN98_RS07760	COG3550	peptidyl-serine autophosphorylation
LIN98_RS07795	COG2927	DNA polymerase III (CHI subunit)
LIN98_RS07800	COG0114	fumarate hydratase activity
LIN98_RS07805	COG2268	Band 7 protein
LIN98_RS07820	COG0778	Nitroreductase
LIN98_RS07825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LIN98_RS07835	COG0814	amino acid
LIN98_RS07840	COG0235	Class ii aldolase
LIN98_RS07845	COG3623	hexulose-6-phosphate isomerase
LIN98_RS07870	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LIN98_RS07875	COG4953	penicillin-binding protein 1C
LIN98_RS07880	COG2855	membrane
LIN98_RS07895	COG0157	Belongs to the NadC ModD family
LIN98_RS07900	COG3842	ATPase activity
LIN98_RS07905	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LIN98_RS07915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LIN98_RS07920	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LIN98_RS07930	COG0307	riboflavin synthase, alpha
LIN98_RS07935	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LIN98_RS07940	COG3657	addiction module killer protein
LIN98_RS07945	COG1534	Rna-binding protein
LIN98_RS07950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LIN98_RS07955	COG2027	D-alanyl-D-alanine carboxypeptidase
LIN98_RS07965	COG0303	'Molybdopterin
LIN98_RS07970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LIN98_RS07980	COG4580	involved in the transport of maltose and maltodextrins
LIN98_RS07985	COG3842	ATPase activity
LIN98_RS07990	COG2182	Extracellular solute-binding protein
LIN98_RS08000	COG3833	ABC-type maltose transport systems, permease component
LIN98_RS08005	COG0366	Alpha amylase catalytic
LIN98_RS08010	COG3842	ATPase activity
LIN98_RS08020	COG1840	ABC-type Fe3 transport system, periplasmic component
LIN98_RS08030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LIN98_RS08045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LIN98_RS08055	COG0633	Ferredoxin
LIN98_RS08065	COG1280	lysine exporter protein (LysE YggA)
LIN98_RS08070	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LIN98_RS08075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LIN98_RS08085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LIN98_RS08090	COG0166	Belongs to the GPI family
LIN98_RS08100	COG0305	Participates in initiation and elongation during chromosome replication
LIN98_RS08105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LIN98_RS08110	COG4591	ABC-type transport system involved in lipoprotein release permease component
LIN98_RS08120	COG4591	ABC-type transport system involved in lipoprotein release permease component
LIN98_RS08125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LIN98_RS08130	COG0512	Glutamine amidotransferase of anthranilate synthase
LIN98_RS08140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LIN98_RS08145	COG4166	transmembrane transport
LIN98_RS08150	COG2832	Protein of unknown function (DUF454)
LIN98_RS08155	COG0339	signal peptide processing
LIN98_RS08160	COG2190	(PTS) system
LIN98_RS08165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LIN98_RS08170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIN98_RS08190	COG2194	sulfuric ester hydrolase activity
LIN98_RS08200	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LIN98_RS08210	COG2246	polysaccharide biosynthetic process
LIN98_RS08220	COG0802	atpase or kinase
LIN98_RS08225	COG0860	N-Acetylmuramoyl-L-alanine amidase
LIN98_RS08225	COG1388	LysM domain
LIN98_RS08230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LIN98_RS08240	COG1923	regulation of RNA biosynthetic process
LIN98_RS08245	COG3283	Transcriptional regulator of aromatic amino acids metabolism
LIN98_RS08255	COG3106	COG3106 Predicted ATPase
LIN98_RS08260	COG4166	transmembrane transport
LIN98_RS08265	COG4168	peptide transport system, permease
LIN98_RS08270	COG4171	peptide transport system, permease
LIN98_RS08275	COG4172	Belongs to the ABC transporter superfamily
LIN98_RS08280	COG4172	Belongs to the ABC transporter superfamily
LIN98_RS08325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LIN98_RS08330	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LIN98_RS08340	COG0024	Methionine aminopeptidase
LIN98_RS08345	COG0316	Belongs to the HesB IscA family
LIN98_RS08355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIN98_RS08360	COG0672	)-iron permease
LIN98_RS08375	COG0577	efflux transmembrane transporter activity
LIN98_RS08385	COG1136	(ABC) transporter
LIN98_RS08385	COG0577	efflux transmembrane transporter activity
LIN98_RS08390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIN98_RS08400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LIN98_RS08405	COG3385	transposase activity
LIN98_RS08420	COG1643	Atp-dependent helicase
LIN98_RS08425	COG2363	Small membrane protein
LIN98_RS08445	COG0247	lactate metabolic process
LIN98_RS08445	COG0277	FAD linked oxidase domain protein
LIN98_RS08460	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LIN98_RS08465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LIN98_RS08470	COG0363	glucosamine-6-phosphate deaminase activity
LIN98_RS08475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LIN98_RS08480	COG1737	Transcriptional regulator
LIN98_RS08490	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LIN98_RS08495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LIN98_RS08505	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
LIN98_RS08510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIN98_RS08510	COG2190	(PTS) system
LIN98_RS08510	COG1263	PTS System
LIN98_RS08535	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LIN98_RS08540	COG3683	transport system, periplasmic component
LIN98_RS08545	COG0488	(ABC) transporter
LIN98_RS08555	COG0187	DNA topoisomerase II activity
LIN98_RS08560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LIN98_RS08565	COG0625	glutathione transferase activity
LIN98_RS08570	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LIN98_RS08580	COG0251	oxidation-reduction process
LIN98_RS08595	COG0463	Glycosyl transferase, family 2
LIN98_RS08605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LIN98_RS08615	COG1560	Kdo2-lipid A biosynthetic process
LIN98_RS08620	COG0730	response to heat
LIN98_RS08625	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LIN98_RS08630	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LIN98_RS08635	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LIN98_RS08635	COG3264	Mechanosensitive ion channel
LIN98_RS08640	COG0318	PFAM AMP-dependent synthetase and ligase
LIN98_RS08645	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LIN98_RS08650	COG0596	Alpha beta hydrolase
LIN98_RS08660	COG0716	FMN binding
LIN98_RS08665	COG0735	belongs to the Fur family
LIN98_RS08670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LIN98_RS08675	COG3094	Invasion gene expression up-regulator, SirB
LIN98_RS08680	COG0023	Translation Initiation Factor
LIN98_RS08690	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LIN98_RS08695	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LIN98_RS08700	COG0776	regulation of translation
LIN98_RS08705	COG0539	negative regulation of cytoplasmic translation
LIN98_RS08715	COG2990	Protein conserved in bacteria
LIN98_RS08720	COG4771	TonB-dependent receptor
LIN98_RS08725	COG0612	Peptidase, M16
LIN98_RS08730	COG1687	branched-chain amino acid
LIN98_RS08735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LIN98_RS08740	COG0583	DNA-binding transcription factor activity
LIN98_RS08770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LIN98_RS08785	COG2920	part of a sulfur-relay system
LIN98_RS08795	COG1121	(ABC) transporter
LIN98_RS08800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LIN98_RS08805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LIN98_RS08825	COG3304	Inner membrane component domain
LIN98_RS08830	COG1289	transmembrane transporter activity
LIN98_RS08845	COG3958	Transketolase
LIN98_RS08850	COG3959	Transketolase, thiamine diphosphate binding domain
LIN98_RS08870	COG0488	(ABC) transporter
LIN98_RS08880	COG1346	cytolysis
LIN98_RS08895	COG1525	nuclease
LIN98_RS08900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LIN98_RS08905	COG2166	iron-sulfur cluster assembly
LIN98_RS08910	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LIN98_RS08910	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LIN98_RS08915	COG1560	Kdo2-lipid A biosynthetic process
LIN98_RS08920	COG3381	protein complex oligomerization
LIN98_RS08925	COG2249	NAD(P)H dehydrogenase (quinone) activity
LIN98_RS08935	COG0330	HflC and HflK could
LIN98_RS08960	COG1858	cytochrome C peroxidase
LIN98_RS08965	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LIN98_RS08970	COG0318	PFAM AMP-dependent synthetase and ligase
LIN98_RS08975	COG3065	identical protein binding
LIN98_RS08980	COG1214	PFAM Peptidase M22, glycoprotease
LIN98_RS08985	COG1199	ATP-dependent helicase activity
LIN98_RS08990	COG0676	glucose-6-phosphate 1-epimerase activity
LIN98_RS08995	COG3118	belongs to the thioredoxin family
LIN98_RS09000	COG0492	ferredoxin-NADP+ reductase activity
LIN98_RS09005	COG4988	ABC transporter
LIN98_RS09010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LIN98_RS09020	COG1946	Acyl-CoA thioesterase
LIN98_RS09025	COG0515	serine threonine protein kinase
LIN98_RS09040	COG1940	carbohydrate kinase activity
LIN98_RS09045	COG0671	phosphoesterase, PA-phosphatase related
LIN98_RS09065	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LIN98_RS09070	COG0708	Exodeoxyribonuclease III
LIN98_RS09095	COG1216	Glycosyl transferase, family 2
LIN98_RS09100	COG2246	polysaccharide biosynthetic process
LIN98_RS09120	COG0463	Glycosyl transferase, family 2
LIN98_RS09155	COG2951	lytic endotransglycosylase activity
LIN98_RS09160	COG1216	Glycosyl transferase, family 2
LIN98_RS09165	COG1216	Glycosyl transferase, family 2
LIN98_RS09175	COG3306	glycosyltransferase involved in LPS biosynthesis
LIN98_RS09185	COG5039	Polysaccharide pyruvyl transferase
LIN98_RS09190	COG2161	toxin-antitoxin pair type II binding
LIN98_RS09195	COG4115	mRNA cleavage
LIN98_RS09200	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LIN98_RS09205	COG1793	dna ligase
LIN98_RS09210	COG0210	DNA helicase
LIN98_RS09215	COG2610	gluconate transmembrane transporter activity
LIN98_RS09220	COG3265	gluconokinase activity
LIN98_RS09225	COG1609	Transcriptional regulator
LIN98_RS09240	COG0437	4 iron, 4 sulfur cluster binding
LIN98_RS09245	COG2864	formate dehydrogenase
LIN98_RS09250	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LIN98_RS09255	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LIN98_RS09260	COG0651	ATP synthesis coupled electron transport
LIN98_RS09265	COG0650	Formate hydrogenlyase subunit 4
LIN98_RS09270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LIN98_RS09275	COG4237	Hydrogenase 4 membrane
LIN98_RS09280	COG0651	ATP synthesis coupled electron transport
LIN98_RS09285	COG3261	NADH dehydrogenase
LIN98_RS09285	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LIN98_RS09290	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LIN98_RS09295	COG3260	NADH ubiquinone oxidoreductase 20
LIN98_RS09305	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LIN98_RS09315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LIN98_RS09325	COG0508	dehydrogenase complex catalyzes the overall conversion of
LIN98_RS09330	COG0567	Dehydrogenase, E1 component
LIN98_RS09340	COG3108	Peptidase M15
LIN98_RS09345	COG2989	Protein conserved in bacteria
LIN98_RS09350	COG0793	Belongs to the peptidase S41A family
LIN98_RS09360	COG2995	paraquat-inducible protein a
LIN98_RS09365	COG3008	intermembrane lipid transfer
LIN98_RS09375	COG3842	ATPase activity
LIN98_RS09380	COG1176	ABC-type spermidine putrescine transport system, permease component I
LIN98_RS09385	COG1177	transmembrane transport
LIN98_RS09390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LIN98_RS09405	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LIN98_RS09410	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LIN98_RS09425	COG1522	sequence-specific DNA binding
LIN98_RS09430	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LIN98_RS09435	COG3025	triphosphatase activity
LIN98_RS09440	COG1392	Phosphate transport regulator
LIN98_RS09445	COG0306	phosphate transporter
LIN98_RS09450	COG4991	sh3 domain protein
LIN98_RS09455	COG0617	tRNA 3'-terminal CCA addition
LIN98_RS09460	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LIN98_RS09465	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LIN98_RS09485	COG1620	l-lactate permease
LIN98_RS09505	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LIN98_RS09510	COG0328	RNA-DNA hybrid ribonuclease activity
LIN98_RS09515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LIN98_RS09535	COG2026	Addiction module toxin, RelE StbE family
LIN98_RS09550	COG0826	peptidase U32
LIN98_RS09560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LIN98_RS09570	COG1862	Preprotein translocase
LIN98_RS09575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LIN98_RS09580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LIN98_RS09590	COG1454	alcohol dehydrogenase
LIN98_RS09590	COG1012	belongs to the aldehyde dehydrogenase family
LIN98_RS09595	COG1172	Belongs to the binding-protein-dependent transport system permease family
LIN98_RS09600	COG1129	ABC transporter
LIN98_RS09615	COG0673	inositol 2-dehydrogenase activity
LIN98_RS09625	COG2271	Major facilitator Superfamily
LIN98_RS09635	COG3718	enzyme involved in inositol metabolism
LIN98_RS09645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LIN98_RS09650	COG3962	Belongs to the TPP enzyme family
LIN98_RS09660	COG0673	inositol 2-dehydrogenase activity
LIN98_RS09665	COG3722	fumarate hydratase activity
LIN98_RS09670	COG0246	Mannitol dehydrogenase
LIN98_RS09680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LIN98_RS09685	COG2274	protein secretion by the type I secretion system
LIN98_RS09690	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
LIN98_RS09695	COG2994	toxin metabolic process
LIN98_RS09705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LIN98_RS09720	COG2813	Specifically methylates the guanine in position
LIN98_RS09725	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LIN98_RS09730	COG0456	acetyltransferase
LIN98_RS09735	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LIN98_RS09750	COG4795	General secretion pathway protein
LIN98_RS09780	COG3064	Membrane
LIN98_RS09785	COG0848	biopolymer transport protein
LIN98_RS09790	COG0811	peptide transport
LIN98_RS09795	COG0824	Thioesterase
LIN98_RS09810	COG1294	oxidase, subunit
LIN98_RS09815	COG1271	oxidase subunit
LIN98_RS09840	COG0641	radical SAM
LIN98_RS09845	COG0217	transcriptional regulatory protein
LIN98_RS09850	COG0494	nUDIX hydrolase
LIN98_RS09860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LIN98_RS09865	COG1755	Isoprenylcysteine carboxyl methyltransferase
LIN98_RS09880	COG2271	Major facilitator Superfamily
LIN98_RS09890	COG0346	lactoylglutathione lyase activity
LIN98_RS09895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LIN98_RS09900	COG2056	Na+-H+ antiporter family
LIN98_RS09915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LIN98_RS09925	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LIN98_RS09930	COG0142	geranyltranstransferase activity
LIN98_RS09945	COG0697	spore germination
LIN98_RS09950	COG0697	spore germination
LIN98_RS09955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LIN98_RS09965	COG4166	transmembrane transport
LIN98_RS09970	COG0601	transmembrane transport
LIN98_RS09975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LIN98_RS09980	COG0444	Belongs to the ABC transporter superfamily
LIN98_RS09985	COG4608	Belongs to the ABC transporter superfamily
LIN98_RS09990	COG0745	RESPONSE REGULATOR receiver
LIN98_RS09995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LIN98_RS10005	COG1611	Belongs to the LOG family
LIN98_RS10015	COG2259	Doxx family
LIN98_RS10025	COG1530	ribonuclease E activity
LIN98_RS10040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LIN98_RS10045	COG0626	cystathionine gamma-synthase activity
LIN98_RS10075	COG2860	membrane
LIN98_RS10090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LIN98_RS10100	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LIN98_RS10105	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LIN98_RS10110	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LIN98_RS10115	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LIN98_RS10125	COG0560	Phosphoserine phosphatase
LIN98_RS10140	COG0728	peptidoglycan biosynthetic process
LIN98_RS10145	COG0196	riboflavin kinase activity
LIN98_RS10160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LIN98_RS10175	COG4974	Belongs to the 'phage' integrase family
LIN98_RS10180	COG2814	Major facilitator Superfamily
LIN98_RS10200	COG3266	domain, Protein
LIN98_RS10200	COG3061	Opacity-associated protein A
LIN98_RS10205	COG1509	lysine 2,3-aminomutase activity
LIN98_RS10215	COG3033	Beta-eliminating lyase
LIN98_RS10220	COG0814	amino acid
LIN98_RS10225	COG2964	Protein conserved in bacteria
LIN98_RS10230	COG5413	integral membrane protein
LIN98_RS10240	COG0204	Acyl-transferase
LIN98_RS10250	COG0697	spore germination
LIN98_RS10255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LIN98_RS10260	COG1882	Formate acetyltransferase
LIN98_RS10265	COG2116	formate transmembrane transporter activity
LIN98_RS10270	COG0537	adenosine 5'-monophosphoramidase activity
LIN98_RS10305	COG3022	response to hydroperoxide
LIN98_RS10310	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LIN98_RS10325	COG0681	Belongs to the peptidase S26 family
LIN98_RS10365	COG0745	RESPONSE REGULATOR receiver