locus-tag	class	description
ANH9381_RS00035	COG4795	General secretion pathway protein
ANH9381_RS00065	COG3064	Membrane
ANH9381_RS00070	COG0848	biopolymer transport protein
ANH9381_RS00075	COG0811	peptide transport
ANH9381_RS00080	COG0824	Thioesterase
ANH9381_RS00090	COG1294	oxidase, subunit
ANH9381_RS00120	COG0641	radical SAM
ANH9381_RS00125	COG0217	transcriptional regulatory protein
ANH9381_RS00130	COG0494	nUDIX hydrolase
ANH9381_RS00140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ANH9381_RS00145	COG1755	Isoprenylcysteine carboxyl methyltransferase
ANH9381_RS00170	COG0346	lactoylglutathione lyase activity
ANH9381_RS00175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ANH9381_RS00180	COG2056	Na+-H+ antiporter family
ANH9381_RS00200	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ANH9381_RS00205	COG0142	geranyltranstransferase activity
ANH9381_RS00220	COG0697	spore germination
ANH9381_RS00225	COG0697	spore germination
ANH9381_RS00230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ANH9381_RS00240	COG4166	transmembrane transport
ANH9381_RS00245	COG0601	transmembrane transport
ANH9381_RS00250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANH9381_RS00255	COG0444	Belongs to the ABC transporter superfamily
ANH9381_RS00260	COG4608	Belongs to the ABC transporter superfamily
ANH9381_RS00265	COG0745	RESPONSE REGULATOR receiver
ANH9381_RS00270	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ANH9381_RS00280	COG1611	Belongs to the LOG family
ANH9381_RS00290	COG2259	Doxx family
ANH9381_RS00315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANH9381_RS00320	COG0626	cystathionine gamma-synthase activity
ANH9381_RS00345	COG2948	multi-organism process
ANH9381_RS00375	COG2860	membrane
ANH9381_RS00390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ANH9381_RS00400	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ANH9381_RS00405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ANH9381_RS00410	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ANH9381_RS00415	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ANH9381_RS00425	COG0560	Phosphoserine phosphatase
ANH9381_RS00440	COG0728	peptidoglycan biosynthetic process
ANH9381_RS00445	COG0196	riboflavin kinase activity
ANH9381_RS00455	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ANH9381_RS00470	COG4974	Belongs to the 'phage' integrase family
ANH9381_RS00475	COG2814	Major facilitator Superfamily
ANH9381_RS00480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ANH9381_RS00495	COG3061	Opacity-associated protein A
ANH9381_RS00495	COG3266	domain, Protein
ANH9381_RS00500	COG1509	lysine 2,3-aminomutase activity
ANH9381_RS00510	COG3033	Beta-eliminating lyase
ANH9381_RS00515	COG0814	amino acid
ANH9381_RS00525	COG5413	integral membrane protein
ANH9381_RS00535	COG0204	Acyl-transferase
ANH9381_RS00545	COG0697	spore germination
ANH9381_RS00550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ANH9381_RS00555	COG1882	Formate acetyltransferase
ANH9381_RS00560	COG2116	formate transmembrane transporter activity
ANH9381_RS00565	COG0537	adenosine 5'-monophosphoramidase activity
ANH9381_RS00600	COG3022	response to hydroperoxide
ANH9381_RS00605	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ANH9381_RS00620	COG0681	Belongs to the peptidase S26 family
ANH9381_RS00655	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ANH9381_RS00660	COG0592	DNA-directed DNA polymerase activity
ANH9381_RS00670	COG2226	methyltransferase
ANH9381_RS00685	COG2801	Transposase and inactivated derivatives
ANH9381_RS00695	COG0281	malic enzyme
ANH9381_RS00700	COG2081	HI0933 family
ANH9381_RS00705	COG3088	subunit of a heme lyase
ANH9381_RS00705	COG4235	cytochrome complex assembly
ANH9381_RS00710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANH9381_RS00715	COG1138	Cytochrome C-type biogenesis protein
ANH9381_RS00725	COG3301	Polysulphide reductase, NrfD
ANH9381_RS00730	COG0437	4 iron, 4 sulfur cluster binding
ANH9381_RS00735	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ANH9381_RS00770	COG1138	Cytochrome C-type biogenesis protein
ANH9381_RS00780	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANH9381_RS00785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANH9381_RS00790	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANH9381_RS00795	COG4133	protoheme IX ABC transporter activity
ANH9381_RS00800	COG2814	Major facilitator Superfamily
ANH9381_RS00810	COG0281	malic enzyme
ANH9381_RS00810	COG0280	phosphate acetyltransferase
ANH9381_RS00825	COG2321	neutral zinc metallopeptidase
ANH9381_RS00840	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ANH9381_RS00845	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ANH9381_RS00850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ANH9381_RS00865	COG0436	Aminotransferase
ANH9381_RS00875	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ANH9381_RS00880	COG2267	carboxylic ester hydrolase activity
ANH9381_RS00895	COG3091	SprT-like family
ANH9381_RS00900	COG0814	amino acid
ANH9381_RS00905	COG1760	l-serine dehydratase
ANH9381_RS00910	COG0252	asparaginase activity
ANH9381_RS00920	COG3063	Type IV pilus biogenesis stability protein PilW
ANH9381_RS00925	COG1426	Protein conserved in bacteria
ANH9381_RS00940	COG2976	Protein conserved in bacteria
ANH9381_RS00950	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ANH9381_RS00955	COG2233	PERMEase
ANH9381_RS00960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ANH9381_RS00965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ANH9381_RS00970	COG1181	Belongs to the D-alanine--D-alanine ligase family
ANH9381_RS00970	COG2918	glutathione biosynthetic process
ANH9381_RS00975	COG2194	sulfuric ester hydrolase activity
ANH9381_RS00980	COG0740	serine-type endopeptidase activity
ANH9381_RS01000	COG3739	integral membrane protein
ANH9381_RS01005	COG2217	Heavy metal translocating P-type atpase
ANH9381_RS01010	COG2608	mercury ion transmembrane transporter activity
ANH9381_RS01015	COG0789	Transcriptional regulator
ANH9381_RS01020	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ANH9381_RS01030	COG2026	Addiction module toxin, RelE StbE family
ANH9381_RS01035	COG1720	tRNA m6t6A37 methyltransferase activity
ANH9381_RS01040	COG1575	Belongs to the MenA family. Type 1 subfamily
ANH9381_RS01050	COG0471	metal ion transport
ANH9381_RS01055	COG3028	Belongs to the UPF0307 family
ANH9381_RS01060	COG0312	modulator of DNA gyrase
ANH9381_RS01065	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ANH9381_RS01070	COG1929	Belongs to the glycerate kinase type-1 family
ANH9381_RS01075	COG2610	gluconate transmembrane transporter activity
ANH9381_RS01080	COG3835	regulator
ANH9381_RS01090	COG0513	Belongs to the DEAD box helicase family
ANH9381_RS01095	COG4785	May be involved in cell division
ANH9381_RS01105	COG2731	YhcH YjgK YiaL family protein
ANH9381_RS01110	COG3023	N-Acetylmuramoyl-L-alanine amidase
ANH9381_RS01115	COG4969	Belongs to the N-Me-Phe pilin family
ANH9381_RS01125	COG1459	type II secretion system
ANH9381_RS01135	COG0237	dephospho-CoA kinase activity
ANH9381_RS01135	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ANH9381_RS01150	COG1115	amino acid carrier protein
ANH9381_RS01180	COG2184	nucleotidyltransferase activity
ANH9381_RS01185	COG4145	pantothenate transmembrane transporter activity
ANH9381_RS01190	COG3924	membrane
ANH9381_RS01195	COG4783	chaperone-mediated protein folding
ANH9381_RS01205	COG0439	Biotin carboxylase
ANH9381_RS01210	COG0511	ligase activity, forming carbon-carbon bonds
ANH9381_RS01235	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ANH9381_RS01245	COG0456	acetyltransferase
ANH9381_RS01250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANH9381_RS01260	COG3078	GTPase activator activity
ANH9381_RS01265	COG0590	tRNA wobble adenosine to inosine editing
ANH9381_RS01285	COG0730	response to heat
ANH9381_RS01295	COG1869	D-ribose catabolic process
ANH9381_RS01305	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANH9381_RS01310	COG1879	ABC-type sugar transport system periplasmic component
ANH9381_RS01315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANH9381_RS01320	COG1278	Cold shock
ANH9381_RS01345	COG0165	Argininosuccinate lyase
ANH9381_RS01350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ANH9381_RS01355	COG0753	catalase activity
ANH9381_RS01360	COG0587	DNA-directed DNA polymerase activity
ANH9381_RS01365	COG1022	Amp-dependent synthetase and ligase
ANH9381_RS01375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ANH9381_RS01375	COG1328	CTP reductase activity
ANH9381_RS01380	COG0602	queuosine metabolic process
ANH9381_RS01385	COG0084	hydrolase, TatD family'
ANH9381_RS01395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ANH9381_RS01420	COG1686	Belongs to the peptidase S11 family
ANH9381_RS01425	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ANH9381_RS01425	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ANH9381_RS01430	COG0772	Belongs to the SEDS family
ANH9381_RS01435	COG0768	penicillin binding
ANH9381_RS01450	COG0513	Belongs to the DEAD box helicase family
ANH9381_RS01455	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ANH9381_RS01460	COG2814	Major facilitator Superfamily
ANH9381_RS01470	COG1028	Short-chain dehydrogenase reductase Sdr
ANH9381_RS01475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ANH9381_RS01495	COG1399	metal-binding, possibly nucleic acid-binding protein
ANH9381_RS01505	COG0500	methyltransferase
ANH9381_RS01510	COG2830	Protein of unknown function (DUF452)
ANH9381_RS01520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANH9381_RS01525	COG0688	phosphatidylethanolamine metabolic process
ANH9381_RS01530	COG0545	Peptidyl-prolyl cis-trans isomerase
ANH9381_RS01550	COG2966	Psort location CytoplasmicMembrane, score
ANH9381_RS01555	COG3610	response to peptide
ANH9381_RS01560	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ANH9381_RS01565	COG1253	flavin adenine dinucleotide binding
ANH9381_RS01575	COG0084	hydrolase, TatD family'
ANH9381_RS01580	COG0470	DNA polymerase III
ANH9381_RS01585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ANH9381_RS01590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ANH9381_RS01595	COG0347	Belongs to the P(II) protein family
ANH9381_RS01600	COG1349	DNA-binding transcription factor activity
ANH9381_RS01605	COG2084	Dehydrogenase
ANH9381_RS01610	COG3395	kinase activity
ANH9381_RS01615	COG0235	Class ii aldolase
ANH9381_RS01620	COG3622	Belongs to the hyi family
ANH9381_RS01625	COG2610	gluconate transmembrane transporter activity
ANH9381_RS01635	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ANH9381_RS01645	COG0561	phosphatase activity
ANH9381_RS01670	COG3085	chromosome segregation
ANH9381_RS01675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANH9381_RS01680	COG3084	Protein conserved in bacteria
ANH9381_RS01685	COG0746	molybdenum cofactor guanylyltransferase activity
ANH9381_RS01695	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_RS01695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_RS01700	COG1105	Belongs to the carbohydrate kinase PfkB family
ANH9381_RS01705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANH9381_RS01705	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ANH9381_RS01705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANH9381_RS01735	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ANH9381_RS01755	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ANH9381_RS01780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ANH9381_RS01785	COG0255	Belongs to the universal ribosomal protein uL29 family
ANH9381_RS01790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ANH9381_RS01795	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ANH9381_RS01800	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ANH9381_RS01805	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ANH9381_RS01810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ANH9381_RS01815	COG0089	rRNA binding
ANH9381_RS01820	COG0088	Forms part of the polypeptide exit tunnel
ANH9381_RS01825	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ANH9381_RS01830	COG0051	transcription antitermination factor activity, RNA binding
ANH9381_RS01835	COG0583	DNA-binding transcription factor activity
ANH9381_RS01840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ANH9381_RS01845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ANH9381_RS01850	COG2031	fatty acid transporter
ANH9381_RS01855	COG0183	Belongs to the thiolase family
ANH9381_RS01865	COG1288	antiporter activity
ANH9381_RS01870	COG0549	Belongs to the carbamate kinase family
ANH9381_RS01875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ANH9381_RS01880	COG0038	chloride channel
ANH9381_RS01885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ANH9381_RS01895	COG1522	sequence-specific DNA binding
ANH9381_RS01900	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ANH9381_RS01910	COG1393	Belongs to the ArsC family
ANH9381_RS01920	COG3036	rescue of stalled ribosome
ANH9381_RS01925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANH9381_RS01930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ANH9381_RS01935	COG2841	Protein conserved in bacteria
ANH9381_RS01950	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ANH9381_RS01960	COG0569	domain protein
ANH9381_RS01965	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ANH9381_RS01965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ANH9381_RS02005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ANH9381_RS02025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ANH9381_RS02030	COG2990	Protein conserved in bacteria
ANH9381_RS02040	COG0606	chelatase, subunit chli
ANH9381_RS02060	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ANH9381_RS02080	COG3501	Rhs element vgr protein
ANH9381_RS02150	COG0606	chelatase, subunit chli
ANH9381_RS02155	COG2861	carbohydrate metabolic process
ANH9381_RS02160	COG4942	peptidase
ANH9381_RS02165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANH9381_RS02180	COG2853	Lipoprotein
ANH9381_RS02185	COG0747	negative chemotaxis
ANH9381_RS02210	COG0814	amino acid
ANH9381_RS02220	COG4783	chaperone-mediated protein folding
ANH9381_RS02225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANH9381_RS02235	COG0552	protein localization to endoplasmic reticulum
ANH9381_RS02240	COG0742	ribosomal rna small subunit methyltransferase
ANH9381_RS02250	COG3715	PTS system
ANH9381_RS02255	COG3716	PTS system mannose fructose sorbose family IID component
ANH9381_RS02260	COG0561	phosphatase activity
ANH9381_RS02265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ANH9381_RS02285	COG1215	transferase activity, transferring glycosyl groups
ANH9381_RS02295	COG2271	Major facilitator Superfamily
ANH9381_RS02325	COG0513	Belongs to the DEAD box helicase family
ANH9381_RS02335	COG3201	nicotinamide mononucleotide transporter
ANH9381_RS02350	COG1238	metal cluster binding
ANH9381_RS02355	COG0110	maltose O-acetyltransferase activity
ANH9381_RS02360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANH9381_RS02385	COG0210	DNA helicase
ANH9381_RS02390	COG5645	(Lipo)protein
ANH9381_RS02400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANH9381_RS02400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANH9381_RS02425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANH9381_RS02435	COG0859	PFAM glycosyl transferase family 9
ANH9381_RS02445	COG3005	denitrification pathway
ANH9381_RS02450	COG3043	anaerobic respiration
ANH9381_RS02455	COG0348	domain, Protein
ANH9381_RS02460	COG0437	4 iron, 4 sulfur cluster binding
ANH9381_RS02465	COG0243	molybdopterin cofactor binding
ANH9381_RS02470	COG3062	negative regulation of establishment of protein localization
ANH9381_RS02475	COG3850	Histidine kinase
ANH9381_RS02480	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ANH9381_RS02490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANH9381_RS02500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANH9381_RS02515	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ANH9381_RS02525	COG0583	DNA-binding transcription factor activity
ANH9381_RS02530	COG2962	Rard protein
ANH9381_RS02545	COG0551	DNA topoisomerase type I activity
ANH9381_RS02570	COG0705	Rhomboid family
ANH9381_RS02575	COG1349	DNA-binding transcription factor activity
ANH9381_RS02585	COG4178	(ABC) transporter
ANH9381_RS02600	COG0233	cytoplasmic translational termination
ANH9381_RS02615	COG0575	Belongs to the CDS family
ANH9381_RS02630	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ANH9381_RS02650	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ANH9381_RS02660	COG0471	metal ion transport
ANH9381_RS02660	COG0490	domain, Protein
ANH9381_RS02665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ANH9381_RS02675	COG0521	Mo-molybdopterin cofactor biosynthetic process
ANH9381_RS02705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ANH9381_RS02715	COG0251	oxidation-reduction process
ANH9381_RS02720	COG2137	regulation of response to DNA damage stimulus
ANH9381_RS02725	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ANH9381_RS02730	COG0488	(ABC) transporter
ANH9381_RS02735	COG0488	(ABC) transporter
ANH9381_RS02740	COG2095	MarC family integral membrane protein
ANH9381_RS02755	COG0582	viral genome integration into host DNA
ANH9381_RS02760	COG2963	transposase activity
ANH9381_RS02770	COG1349	DNA-binding transcription factor activity
ANH9381_RS02780	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ANH9381_RS02790	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ANH9381_RS02810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANH9381_RS02815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANH9381_RS02820	COG0765	amino acid transport
ANH9381_RS02825	COG1126	abc transporter atp-binding protein
ANH9381_RS02830	COG2168	tRNA wobble position uridine thiolation
ANH9381_RS02840	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ANH9381_RS02845	COG2964	Protein conserved in bacteria
ANH9381_RS02850	COG0545	Peptidyl-prolyl cis-trans isomerase
ANH9381_RS02855	COG2900	Belongs to the SlyX family
ANH9381_RS02860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ANH9381_RS02860	COG0678	peroxiredoxin activity
ANH9381_RS02865	COG0583	DNA-binding transcription factor activity
ANH9381_RS02870	COG1309	transcriptional regulator
ANH9381_RS02875	COG1132	(ABC) transporter
ANH9381_RS02880	COG4988	ABC transporter
ANH9381_RS02885	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ANH9381_RS02890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ANH9381_RS02895	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ANH9381_RS02905	COG1045	serine acetyltransferase
ANH9381_RS02910	COG1494	fructose-1,6-bisphosphatase
ANH9381_RS02920	COG0716	FMN binding
ANH9381_RS02930	COG0702	epimerase
ANH9381_RS02935	COG1733	regulation of RNA biosynthetic process
ANH9381_RS02945	COG3312	ion transport
ANH9381_RS02965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANH9381_RS02975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ANH9381_RS02990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ANH9381_RS03010	COG0732	type I restriction modification DNA specificity domain
ANH9381_RS03020	COG3716	PTS system mannose fructose sorbose family IID component
ANH9381_RS03025	COG3715	PTS system
ANH9381_RS03030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANH9381_RS03030	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_RS03035	COG2814	Major facilitator Superfamily
ANH9381_RS03040	COG1609	Transcriptional regulator
ANH9381_RS03040	COG2207	Transcriptional regulator
ANH9381_RS03045	COG1757	Na H antiporter
ANH9381_RS03050	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ANH9381_RS03055	COG4214	carbohydrate transport
ANH9381_RS03060	COG1129	ABC transporter
ANH9381_RS03070	COG2115	Belongs to the xylose isomerase family
ANH9381_RS03075	COG1070	Carbohydrate kinase
ANH9381_RS03085	COG2801	Transposase and inactivated derivatives
ANH9381_RS03090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ANH9381_RS03095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ANH9381_RS03100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANH9381_RS03105	COG3719	Belongs to the RNase T2 family
ANH9381_RS03115	COG0191	fructose-bisphosphate aldolase activity
ANH9381_RS03120	COG3307	-O-antigen
ANH9381_RS03125	COG2267	carboxylic ester hydrolase activity
ANH9381_RS03130	COG0561	phosphatase activity
ANH9381_RS03140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANH9381_RS03145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANH9381_RS03150	COG2177	Part of the ABC transporter FtsEX involved in
ANH9381_RS03155	COG2884	Cell division ATP-binding protein ftsE
ANH9381_RS03165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ANH9381_RS03195	COG1238	metal cluster binding
ANH9381_RS03205	COG1388	LysM domain
ANH9381_RS03205	COG4942	peptidase
ANH9381_RS03215	COG0463	Glycosyl transferase, family 2
ANH9381_RS03220	COG1519	Transferase
ANH9381_RS03235	COG0859	PFAM glycosyl transferase family 9
ANH9381_RS03240	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ANH9381_RS03245	COG4977	sequence-specific DNA binding
ANH9381_RS03245	COG1917	Cupin 2, conserved barrel domain protein
ANH9381_RS03250	COG1132	(ABC) transporter
ANH9381_RS03285	COG0758	DNA mediated transformation
ANH9381_RS03290	COG0584	glycerophosphoryl diester phosphodiesterase
ANH9381_RS03295	COG2271	Major facilitator Superfamily
ANH9381_RS03310	COG1077	Cell shape determining protein MreB Mrl
ANH9381_RS03315	COG1792	Involved in formation and maintenance of cell shape
ANH9381_RS03320	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ANH9381_RS03345	COG0006	proline dipeptidase activity
ANH9381_RS03360	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ANH9381_RS03375	COG1496	oxidoreductase activity
ANH9381_RS03385	COG0778	Nitroreductase
ANH9381_RS03395	COG0762	integral membrane protein
ANH9381_RS03405	COG0500	methyltransferase
ANH9381_RS03410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANH9381_RS03415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANH9381_RS03420	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ANH9381_RS03425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ANH9381_RS03440	COG3306	glycosyltransferase involved in LPS biosynthesis
ANH9381_RS03450	COG3306	glycosyltransferase involved in LPS biosynthesis
ANH9381_RS03490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ANH9381_RS03500	COG1309	transcriptional regulator
ANH9381_RS03515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANH9381_RS03520	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ANH9381_RS03525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ANH9381_RS03530	COG4972	Pilus assembly protein
ANH9381_RS03550	COG4796	Type ii and iii secretion system protein
ANH9381_RS03565	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ANH9381_RS03575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ANH9381_RS03585	COG2801	Transposase and inactivated derivatives
ANH9381_RS03605	COG0459	protein refolding
ANH9381_RS03610	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ANH9381_RS03625	COG0859	PFAM glycosyl transferase family 9
ANH9381_RS03635	COG2801	Transposase and inactivated derivatives
ANH9381_RS03670	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ANH9381_RS03675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ANH9381_RS03685	COG1739	Uncharacterized protein family UPF0029
ANH9381_RS03690	COG3172	ATPase kinase involved in NAD metabolism
ANH9381_RS03695	COG2129	metallophosphoesterase
ANH9381_RS03700	COG0814	amino acid
ANH9381_RS03735	COG0201	protein transport
ANH9381_RS03755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ANH9381_RS03765	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ANH9381_RS03775	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ANH9381_RS03800	COG1114	Component of the transport system for branched-chain amino acids
ANH9381_RS03805	COG0140	phosphoribosyl-ATP diphosphatase activity
ANH9381_RS03805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ANH9381_RS03815	COG1040	competence protein
ANH9381_RS03820	COG0561	phosphatase activity
ANH9381_RS03825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ANH9381_RS03830	COG1596	polysaccharide export
ANH9381_RS03830	COG1555	photosystem II stabilization
ANH9381_RS03850	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ANH9381_RS03855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ANH9381_RS03865	COG1011	Hydrolase
ANH9381_RS03890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANH9381_RS03945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANH9381_RS03955	COG1028	Short-chain dehydrogenase reductase Sdr
ANH9381_RS03960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANH9381_RS03975	COG4545	Glutaredoxin-related protein
ANH9381_RS03980	COG1794	racemase activity, acting on amino acids and derivatives
ANH9381_RS03990	COG0363	glucosamine-6-phosphate deaminase activity
ANH9381_RS03995	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ANH9381_RS04000	COG1218	3'(2'),5'-bisphosphate nucleotidase
ANH9381_RS04010	COG1297	OPT oligopeptide transporter protein
ANH9381_RS04015	COG3059	membrane
ANH9381_RS04025	COG0494	nUDIX hydrolase
ANH9381_RS04030	COG1011	Hydrolase
ANH9381_RS04035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ANH9381_RS04040	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ANH9381_RS04045	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANH9381_RS04050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANH9381_RS04055	COG0805	protein transport
ANH9381_RS04080	COG4545	Glutaredoxin-related protein
ANH9381_RS04090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANH9381_RS04090	COG2221	Nitrite and sulphite reductase 4Fe-4S
ANH9381_RS04095	COG3381	protein complex oligomerization
ANH9381_RS04100	COG3302	dmso reductase anchor subunit
ANH9381_RS04105	COG0437	4 iron, 4 sulfur cluster binding
ANH9381_RS04110	COG0243	molybdopterin cofactor binding
ANH9381_RS04145	COG0848	biopolymer transport protein
ANH9381_RS04150	COG0811	peptide transport
ANH9381_RS04155	COG4536	flavin adenine dinucleotide binding
ANH9381_RS04165	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ANH9381_RS04170	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ANH9381_RS04175	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ANH9381_RS04185	COG4221	oxidoreductase activity
ANH9381_RS04190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ANH9381_RS04210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ANH9381_RS04215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ANH9381_RS04220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ANH9381_RS04225	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
ANH9381_RS04230	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
ANH9381_RS04245	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ANH9381_RS04250	COG1466	dna polymerase III delta subunit
ANH9381_RS04255	COG0494	nUDIX hydrolase
ANH9381_RS04270	COG4701	Protein of unknown function (DUF721)
ANH9381_RS04275	COG0789	Transcriptional regulator
ANH9381_RS04280	COG2801	Transposase and inactivated derivatives
ANH9381_RS04290	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ANH9381_RS04295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ANH9381_RS04300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ANH9381_RS04305	COG1381	Involved in DNA repair and RecF pathway recombination
ANH9381_RS04310	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ANH9381_RS04325	COG0354	folic acid binding
ANH9381_RS04330	COG1561	YicC-like family, N-terminal region
ANH9381_RS04340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ANH9381_RS04350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ANH9381_RS04360	COG3842	ATPase activity
ANH9381_RS04365	COG1178	ABC-type Fe3 transport system permease component
ANH9381_RS04370	COG1840	ABC-type Fe3 transport system, periplasmic component
ANH9381_RS04375	COG3171	Protein conserved in bacteria
ANH9381_RS04385	COG1194	a g-specific adenine glycosylase
ANH9381_RS04410	COG3056	Lipoprotein
ANH9381_RS04415	COG0271	Belongs to the BolA IbaG family
ANH9381_RS04430	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ANH9381_RS04435	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ANH9381_RS04440	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ANH9381_RS04445	COG2871	sodium ion transport
ANH9381_RS04450	COG1477	protein flavinylation
ANH9381_RS04455	COG2991	Protein conserved in bacteria
ANH9381_RS04465	COG0148	phosphopyruvate hydratase activity
ANH9381_RS04480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ANH9381_RS04490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ANH9381_RS04495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANH9381_RS04500	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ANH9381_RS04515	COG3956	TIGRFAM MazG family protein
ANH9381_RS04520	COG0402	S-adenosylhomocysteine deaminase activity
ANH9381_RS04525	COG3083	sulfuric ester hydrolase activity
ANH9381_RS04530	COG3082	Protein of unknown function (DUF1414)
ANH9381_RS04540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ANH9381_RS04545	COG0745	RESPONSE REGULATOR receiver
ANH9381_RS04550	COG2205	protein histidine kinase activity
ANH9381_RS04555	COG0786	glutamate:sodium symporter activity
ANH9381_RS04570	COG3012	SEC-C Motif Domain Protein
ANH9381_RS04575	COG2258	MOSC domain
ANH9381_RS04580	COG0433	COG0433 Predicted ATPase
ANH9381_RS04595	COG0656	L-ascorbic acid biosynthetic process
ANH9381_RS04600	COG0667	Aldo Keto reductase
ANH9381_RS04610	COG2272	Belongs to the type-B carboxylesterase lipase family
ANH9381_RS04635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ANH9381_RS04640	COG1349	DNA-binding transcription factor activity
ANH9381_RS04650	COG3068	Protein conserved in bacteria
ANH9381_RS04655	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ANH9381_RS04675	COG0248	Ppx GppA phosphatase
ANH9381_RS04680	COG2911	Protein conserved in bacteria
ANH9381_RS04685	COG0729	surface antigen
ANH9381_RS04690	COG2197	response regulator
ANH9381_RS04700	COG0181	hydroxymethylbilane synthase activity
ANH9381_RS04710	COG2959	enzyme of heme biosynthesis
ANH9381_RS04715	COG3071	HemY protein
ANH9381_RS04720	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ANH9381_RS04730	COG1595	DNA-templated transcription, initiation
ANH9381_RS04740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ANH9381_RS04750	COG0471	metal ion transport
ANH9381_RS04760	COG2183	response to ionizing radiation
ANH9381_RS04770	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANH9381_RS04775	COG1129	ABC transporter
ANH9381_RS04780	COG1879	ABC-type sugar transport system periplasmic component
ANH9381_RS04785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANH9381_RS04810	COG1072	(Pantothenic acid kinase))
ANH9381_RS04815	COG0187	DNA topoisomerase II activity
ANH9381_RS04820	COG0514	ATP-dependent DNA helicase (RecQ)
ANH9381_RS04830	COG0019	diaminopimelate decarboxylase activity
ANH9381_RS04835	COG3477	response to acidic pH
ANH9381_RS04840	COG2818	Glycosylase
ANH9381_RS04845	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ANH9381_RS04855	COG2195	Cleaves the N-terminal amino acid of tripeptides
ANH9381_RS04860	COG0300	oxidoreductase activity
ANH9381_RS04865	COG1763	Mo-molybdopterin cofactor biosynthetic process
ANH9381_RS04870	COG3086	response to oxidative stress
ANH9381_RS04875	COG3026	antisigma factor binding
ANH9381_RS04880	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ANH9381_RS04885	COG1595	DNA-templated transcription, initiation
ANH9381_RS04900	COG0442	prolyl-tRNA aminoacylation
ANH9381_RS04905	COG1921	L-seryl-tRNASec selenium transferase activity
ANH9381_RS04910	COG3276	selenocysteine insertion sequence binding
ANH9381_RS04930	COG0733	neurotransmitter:sodium symporter activity
ANH9381_RS05000	COG4964	Belongs to the GSP D family
ANH9381_RS05020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ANH9381_RS05030	COG1444	tRNA N-acetyltransferase activity
ANH9381_RS05035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ANH9381_RS05045	COG1126	abc transporter atp-binding protein
ANH9381_RS05050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANH9381_RS05055	COG4215	(ABC) transporter
ANH9381_RS05060	COG4160	amino acid transport
ANH9381_RS05065	COG1966	Carbon starvation protein
ANH9381_RS05080	COG3116	cell division
ANH9381_RS05095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ANH9381_RS05105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ANH9381_RS05115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ANH9381_RS05130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ANH9381_RS05135	COG0849	cell division
ANH9381_RS05140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ANH9381_RS05150	COG1605	Chorismate mutase
ANH9381_RS05150	COG0077	Prephenate dehydratase
ANH9381_RS05155	COG0326	Molecular chaperone. Has ATPase activity
ANH9381_RS05160	COG1393	Belongs to the ArsC family
ANH9381_RS05170	COG1876	peptidase activity
ANH9381_RS05175	COG0494	nUDIX hydrolase
ANH9381_RS05180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ANH9381_RS05215	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ANH9381_RS05225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ANH9381_RS05230	COG1053	succinate dehydrogenase
ANH9381_RS05240	COG1120	ATPase activity
ANH9381_RS05245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANH9381_RS05250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANH9381_RS05255	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ANH9381_RS05260	COG1408	metallophosphoesterase
ANH9381_RS05270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ANH9381_RS05275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANH9381_RS05295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ANH9381_RS05305	COG0741	lytic transglycosylase activity
ANH9381_RS05310	COG2350	Protein conserved in bacteria
ANH9381_RS05315	COG1607	acyl-coa hydrolase
ANH9381_RS05330	COG3047	cAMP biosynthetic process
ANH9381_RS05335	COG0497	DNA recombination
ANH9381_RS05345	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ANH9381_RS05355	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ANH9381_RS05355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANH9381_RS05360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANH9381_RS05365	COG5002	protein histidine kinase activity
ANH9381_RS05365	COG0784	Response regulator, receiver
ANH9381_RS05365	COG2198	Histidine kinase
ANH9381_RS05370	COG4211	Belongs to the binding-protein-dependent transport system permease family
ANH9381_RS05380	COG1879	ABC-type sugar transport system periplasmic component
ANH9381_RS05385	COG1609	Transcriptional regulator
ANH9381_RS05390	COG1085	galactose-1-phosphate uridylyltransferase
ANH9381_RS05395	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ANH9381_RS05400	COG2017	converts alpha-aldose to the beta-anomer
ANH9381_RS05415	COG0471	metal ion transport
ANH9381_RS05420	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ANH9381_RS05420	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
ANH9381_RS05425	COG3051	citrate lyase alpha subunit
ANH9381_RS05430	COG2301	Belongs to the HpcH HpaI aldolase family
ANH9381_RS05440	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ANH9381_RS05445	COG4535	Mg2 and Co2 transporter CorC
ANH9381_RS05465	COG0105	UTP biosynthetic process
ANH9381_RS05475	COG0489	protein tyrosine kinase activity
ANH9381_RS05480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANH9381_RS05480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANH9381_RS05485	COG2975	iron-sulfur cluster assembly
ANH9381_RS05490	COG0633	Ferredoxin
ANH9381_RS05495	COG0443	Heat shock 70 kDa protein
ANH9381_RS05510	COG0822	iron-sulfur transferase activity
ANH9381_RS05520	COG1959	2 iron, 2 sulfur cluster binding
ANH9381_RS05525	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ANH9381_RS05550	COG1840	ABC-type Fe3 transport system, periplasmic component
ANH9381_RS05555	COG1840	ABC-type Fe3 transport system, periplasmic component
ANH9381_RS05560	COG1840	ABC-type Fe3 transport system, periplasmic component
ANH9381_RS05610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ANH9381_RS05615	COG1530	ribonuclease E activity
ANH9381_RS05620	COG2999	glutathione oxidoreductase activity
ANH9381_RS05625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ANH9381_RS05690	COG3021	interspecies interaction between organisms
ANH9381_RS05735	COG0626	cystathionine gamma-synthase activity
ANH9381_RS05750	COG2337	Toxic component of a toxin-antitoxin (TA) module
ANH9381_RS05755	COG0484	heat shock protein binding
ANH9381_RS05765	COG5339	Protein conserved in bacteria
ANH9381_RS05775	COG3102	Protein conserved in bacteria
ANH9381_RS05780	COG3133	Outer membrane lipoprotein
ANH9381_RS05785	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ANH9381_RS05790	COG2890	protein-(glutamine-N5) methyltransferase activity
ANH9381_RS05800	COG0791	NLP P60 protein
ANH9381_RS05805	COG3100	YcgL domain-containing protein
ANH9381_RS05820	COG2062	phosphohistidine phosphatase, SixA
ANH9381_RS05830	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ANH9381_RS05835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ANH9381_RS05840	COG2801	Transposase and inactivated derivatives
ANH9381_RS05855	COG2963	transposase activity
ANH9381_RS05860	COG0517	IMP dehydrogenase activity
ANH9381_RS05860	COG0516	GMP reductase activity
ANH9381_RS05865	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ANH9381_RS05865	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ANH9381_RS05900	COG4172	Belongs to the ABC transporter superfamily
ANH9381_RS05905	COG4172	Belongs to the ABC transporter superfamily
ANH9381_RS05910	COG4171	peptide transport system, permease
ANH9381_RS05915	COG4168	peptide transport system, permease
ANH9381_RS05920	COG4166	transmembrane transport
ANH9381_RS05925	COG3106	COG3106 Predicted ATPase
ANH9381_RS05935	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ANH9381_RS05940	COG1923	regulation of RNA biosynthetic process
ANH9381_RS05950	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ANH9381_RS05955	COG0860	N-Acetylmuramoyl-L-alanine amidase
ANH9381_RS05955	COG1388	LysM domain
ANH9381_RS05960	COG0802	atpase or kinase
ANH9381_RS05975	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ANH9381_RS05985	COG2194	sulfuric ester hydrolase activity
ANH9381_RS05990	COG2194	sulfuric ester hydrolase activity
ANH9381_RS06015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_RS06020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANH9381_RS06025	COG2190	(PTS) system
ANH9381_RS06030	COG0339	signal peptide processing
ANH9381_RS06035	COG2832	Protein of unknown function (DUF454)
ANH9381_RS06045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANH9381_RS06055	COG0512	Glutamine amidotransferase of anthranilate synthase
ANH9381_RS06060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANH9381_RS06070	COG4591	ABC-type transport system involved in lipoprotein release permease component
ANH9381_RS06080	COG4591	ABC-type transport system involved in lipoprotein release permease component
ANH9381_RS06085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ANH9381_RS06090	COG0305	Participates in initiation and elongation during chromosome replication
ANH9381_RS06100	COG0166	Belongs to the GPI family
ANH9381_RS06105	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ANH9381_RS06115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ANH9381_RS06120	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ANH9381_RS06125	COG1280	lysine exporter protein (LysE YggA)
ANH9381_RS06135	COG0633	Ferredoxin
ANH9381_RS06145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANH9381_RS06155	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANH9381_RS06165	COG1840	ABC-type Fe3 transport system, periplasmic component
ANH9381_RS06175	COG3842	ATPase activity
ANH9381_RS06180	COG0366	Alpha amylase catalytic
ANH9381_RS06185	COG3833	ABC-type maltose transport systems, permease component
ANH9381_RS06195	COG2182	Extracellular solute-binding protein
ANH9381_RS06200	COG3842	ATPase activity
ANH9381_RS06205	COG4580	involved in the transport of maltose and maltodextrins
ANH9381_RS06215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ANH9381_RS06220	COG0303	'Molybdopterin
ANH9381_RS06230	COG2027	D-alanyl-D-alanine carboxypeptidase
ANH9381_RS06235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ANH9381_RS06240	COG1534	Rna-binding protein
ANH9381_RS06245	COG3657	addiction module killer protein
ANH9381_RS06250	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ANH9381_RS06255	COG0307	riboflavin synthase, alpha
ANH9381_RS06265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ANH9381_RS06270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ANH9381_RS06275	COG0725	ABC transporter, periplasmic molybdate-binding protein
ANH9381_RS06280	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ANH9381_RS06285	COG3842	ATPase activity
ANH9381_RS06290	COG0157	Belongs to the NadC ModD family
ANH9381_RS06305	COG2855	membrane
ANH9381_RS06310	COG4953	penicillin-binding protein 1C
ANH9381_RS06315	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ANH9381_RS06340	COG3623	hexulose-6-phosphate isomerase
ANH9381_RS06350	COG0814	amino acid
ANH9381_RS06360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ANH9381_RS06365	COG0778	Nitroreductase
ANH9381_RS06380	COG0114	fumarate hydratase activity
ANH9381_RS06385	COG2927	DNA polymerase III (CHI subunit)
ANH9381_RS06415	COG3550	peptidyl-serine autophosphorylation
ANH9381_RS06425	COG2814	Major facilitator Superfamily
ANH9381_RS06430	COG1566	PFAM secretion protein HlyD family protein
ANH9381_RS06435	COG0783	Belongs to the Dps family
ANH9381_RS06445	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ANH9381_RS06450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ANH9381_RS06455	COG0602	queuosine metabolic process
ANH9381_RS06460	COG0720	synthase
ANH9381_RS06465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ANH9381_RS06475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANH9381_RS06480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ANH9381_RS06485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANH9381_RS06490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ANH9381_RS06495	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
ANH9381_RS06500	COG0310	cobalt ion transport
ANH9381_RS06505	COG0310	cobalt ion transport
ANH9381_RS06510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ANH9381_RS06515	COG1122	ATPase activity
ANH9381_RS06520	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ANH9381_RS06525	COG0409	Hydrogenase expression formation protein
ANH9381_RS06530	COG0309	Hydrogenase expression formation protein (HypE)
ANH9381_RS06545	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ANH9381_RS06550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ANH9381_RS06555	COG0795	lipopolysaccharide-transporting ATPase activity
ANH9381_RS06560	COG0795	lipopolysaccharide-transporting ATPase activity
ANH9381_RS06565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ANH9381_RS06570	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ANH9381_RS06575	COG4149	molybdate abc transporter
ANH9381_RS06580	COG0725	ABC transporter, periplasmic molybdate-binding protein
ANH9381_RS06585	COG2005	Transcriptional regulator
ANH9381_RS06590	COG0471	metal ion transport
ANH9381_RS06600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANH9381_RS06605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANH9381_RS06605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANH9381_RS06610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ANH9381_RS06620	COG0583	DNA-binding transcription factor activity
ANH9381_RS06625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANH9381_RS06635	COG0039	L-malate dehydrogenase activity
ANH9381_RS06640	COG1438	arginine binding
ANH9381_RS06645	COG1090	epimerase
ANH9381_RS06650	COG4657	Part of a membrane complex involved in electron transport
ANH9381_RS06680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ANH9381_RS06690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANH9381_RS06700	COG0739	heme binding
ANH9381_RS06705	COG4604	ABC transporter, ATP-binding protein
ANH9381_RS06710	COG4605	iron ion homeostasis
ANH9381_RS06715	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANH9381_RS06720	COG4607	ABC-type enterochelin transport system periplasmic component
ANH9381_RS06735	COG3111	PFAM Bacterial OB fold (BOF) protein
ANH9381_RS06760	COG3392	D12 class N6 adenine-specific DNA methyltransferase
ANH9381_RS06770	COG0642	Histidine kinase
ANH9381_RS06775	COG0405	Gamma-glutamyltransferase
ANH9381_RS06790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANH9381_RS06795	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ANH9381_RS06800	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
ANH9381_RS06835	COG1518	maintenance of DNA repeat elements
ANH9381_RS06850	COG4143	(ABC) transporter
ANH9381_RS06855	COG1178	ABC-type Fe3 transport system permease component
ANH9381_RS06860	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ANH9381_RS06870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANH9381_RS06875	COG3105	Protein conserved in bacteria
ANH9381_RS06890	COG3422	double-strand break repair
ANH9381_RS06905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANH9381_RS06915	COG1940	carbohydrate kinase activity
ANH9381_RS06915	COG1846	Transcriptional regulator
ANH9381_RS06940	COG0563	adenylate kinase activity
ANH9381_RS06945	COG2814	Major facilitator Superfamily
ANH9381_RS06950	COG0375	protein maturation
ANH9381_RS06955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANH9381_RS06960	COG3152	Membrane
ANH9381_RS06965	COG2252	PERMEase
ANH9381_RS06980	COG0825	malonyl-CoA metabolic process
ANH9381_RS06985	COG2351	hydroxyisourate hydrolase activity
ANH9381_RS07060	COG1598	PFAM Uncharacterised protein family UPF0150
ANH9381_RS07070	COG5301	cellulose 1,4-beta-cellobiosidase activity
ANH9381_RS07080	COG0582	viral genome integration into host DNA
ANH9381_RS07090	COG3041	Addiction module toxin RelE StbE family
ANH9381_RS07095	COG3077	Addiction module antitoxin, RelB DinJ family
ANH9381_RS07100	COG3069	C4-dicarboxylate transmembrane transporter activity
ANH9381_RS07115	COG0195	Participates in both transcription termination and antitermination
ANH9381_RS07140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ANH9381_RS07150	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ANH9381_RS07170	COG1489	DNA binding
ANH9381_RS07180	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ANH9381_RS07185	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ANH9381_RS07195	COG3177	Filamentation induced by cAMP protein fic
ANH9381_RS07205	COG3842	ATPase activity
ANH9381_RS07210	COG1175	transmembrane transport
ANH9381_RS07215	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANH9381_RS07225	COG0322	excinuclease ABC activity
ANH9381_RS07235	COG2835	tetraacyldisaccharide 4'-kinase activity
ANH9381_RS07240	COG1663	tetraacyldisaccharide 4'-kinase activity
ANH9381_RS07245	COG1132	(ABC) transporter
ANH9381_RS07250	COG2333	competence protein COMEC
ANH9381_RS07250	COG0658	competence protein
ANH9381_RS07255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ANH9381_RS07260	COG0617	tRNA 3'-terminal CCA addition
ANH9381_RS07265	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ANH9381_RS07275	COG0857	belongs to the CobB CobQ family
ANH9381_RS07275	COG0280	phosphate acetyltransferase
ANH9381_RS07280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ANH9381_RS07285	COG3092	negative regulation of chromosome organization
ANH9381_RS07290	COG1286	toxin biosynthetic process
ANH9381_RS07295	COG1640	4-alpha-glucanotransferase
ANH9381_RS07300	COG0058	SHG alpha-glucan phosphorylase activity
ANH9381_RS07305	COG2909	trisaccharide binding
ANH9381_RS07315	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ANH9381_RS07320	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANH9381_RS07325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANH9381_RS07330	COG0778	Nitroreductase
ANH9381_RS07335	COG0616	signal peptide processing
ANH9381_RS07340	COG1605	Chorismate mutase
ANH9381_RS07340	COG0287	Prephenate dehydrogenase
ANH9381_RS07345	COG1605	Chorismate mutase
ANH9381_RS07345	COG0287	Prephenate dehydrogenase
ANH9381_RS07350	COG0009	L-threonylcarbamoyladenylate synthase
ANH9381_RS07360	COG0583	DNA-binding transcription factor activity
ANH9381_RS07370	COG3099	Belongs to the UPF0263 family
ANH9381_RS07380	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ANH9381_RS07385	COG2949	membrane
ANH9381_RS07410	COG0785	Cytochrome C biogenesis protein
ANH9381_RS07415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANH9381_RS07415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANH9381_RS07420	COG0288	reversible hydration of carbon dioxide
ANH9381_RS07425	COG2823	Periplasmic or secreted lipoprotein
ANH9381_RS07430	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ANH9381_RS07435	COG0792	nuclease activity
ANH9381_RS07445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ANH9381_RS07465	COG0616	signal peptide processing
ANH9381_RS07470	COG2885	chlorophyll binding
ANH9381_RS07470	COG3047	cAMP biosynthetic process
ANH9381_RS07500	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ANH9381_RS07505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ANH9381_RS07510	COG3684	Belongs to the aldolase LacD family
ANH9381_RS07520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_RS07525	COG3414	Phosphotransferase system galactitol-specific IIB component
ANH9381_RS07530	COG3775	system Galactitol-specific IIC component
ANH9381_RS07535	COG1063	alcohol dehydrogenase
ANH9381_RS07540	COG1349	DNA-binding transcription factor activity
ANH9381_RS07550	COG0142	geranyltranstransferase activity
ANH9381_RS07565	COG0285	dihydrofolate synthase activity
ANH9381_RS07570	COG0406	alpha-ribazole phosphatase activity
ANH9381_RS07575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ANH9381_RS07580	COG2431	L-lysine efflux transmembrane transporter activity
ANH9381_RS07585	COG0564	pseudouridine synthase activity
ANH9381_RS07595	COG2824	Alkylphosphonate utilization operon protein PhnA
ANH9381_RS07625	COG1538	Outer membrane efflux protein
ANH9381_RS07635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANH9381_RS07660	COG1523	belongs to the glycosyl hydrolase 13 family
ANH9381_RS07675	COG0058	SHG alpha-glucan phosphorylase activity
ANH9381_RS07680	COG0586	Pfam SNARE associated Golgi protein
ANH9381_RS07685	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ANH9381_RS07695	COG1686	Belongs to the peptidase S11 family
ANH9381_RS07700	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
ANH9381_RS07720	COG0697	spore germination
ANH9381_RS07725	COG2925	Exonuclease
ANH9381_RS07750	COG1528	Iron-storage protein
ANH9381_RS07755	COG1528	Iron-storage protein
ANH9381_RS07760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANH9381_RS07765	COG0589	response to stress
ANH9381_RS07770	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
ANH9381_RS07780	COG0613	PHP domain protein
ANH9381_RS07785	COG0167	dihydroorotate dehydrogenase activity
ANH9381_RS07790	COG0308	aminopeptidase N
ANH9381_RS07795	COG1448	Aminotransferase
ANH9381_RS07805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANH9381_RS07810	COG1129	ABC transporter
ANH9381_RS07810	COG0842	Transport permease protein
ANH9381_RS07815	COG0842	Transport permease protein
ANH9381_RS07830	COG1120	ATPase activity
ANH9381_RS07835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ANH9381_RS07840	COG3585	molybdate ion transport
ANH9381_RS07855	COG1120	ATPase activity
ANH9381_RS07860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANH9381_RS07870	COG4774	siderophore transport
ANH9381_RS07885	COG0791	NLP P60 protein
ANH9381_RS07900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ANH9381_RS07910	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ANH9381_RS07910	COG0517	IMP dehydrogenase activity
ANH9381_RS07915	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ANH9381_RS07920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ANH9381_RS07925	COG0512	Glutamine amidotransferase of anthranilate synthase
ANH9381_RS07930	COG1942	4-Oxalocrotonate Tautomerase
ANH9381_RS07935	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ANH9381_RS07945	COG3093	addiction module antidote protein HigA
ANH9381_RS07950	COG0135	phosphoribosylanthranilate isomerase activity
ANH9381_RS07950	COG0134	indole-3-glycerol-phosphate synthase activity
ANH9381_RS07960	COG0298	carbon dioxide binding
ANH9381_RS07970	COG3630	sodium ion export across plasma membrane
ANH9381_RS07990	COG4221	oxidoreductase activity
ANH9381_RS07995	COG0133	tryptophan synthase activity
ANH9381_RS08005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANH9381_RS08015	COG0469	pyruvate kinase activity
ANH9381_RS08030	COG1879	ABC-type sugar transport system periplasmic component
ANH9381_RS08040	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANH9381_RS08055	COG2390	Transcriptional regulator
ANH9381_RS08065	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ANH9381_RS08070	COG1940	carbohydrate kinase activity
ANH9381_RS08080	COG2969	positive regulation of protein catabolic process
ANH9381_RS08095	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ANH9381_RS08105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ANH9381_RS08130	COG3005	denitrification pathway
ANH9381_RS08135	COG0243	molybdopterin cofactor binding
ANH9381_RS08140	COG2315	Protein conserved in bacteria
ANH9381_RS08145	COG0471	metal ion transport
ANH9381_RS08160	COG0101	tRNA pseudouridine synthase activity
ANH9381_RS08180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ANH9381_RS08190	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ANH9381_RS08200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ANH9381_RS08205	COG1067	ATP-dependent peptidase activity
ANH9381_RS08215	COG1278	Cold shock
ANH9381_RS08220	COG3140	Belongs to the UPF0181 family
ANH9381_RS08230	COG3098	single-species biofilm formation
ANH9381_RS08235	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ANH9381_RS08240	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ANH9381_RS08240	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ANH9381_RS08255	COG0745	RESPONSE REGULATOR receiver
ANH9381_RS08280	COG3842	ATPase activity
ANH9381_RS08285	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ANH9381_RS08290	COG1178	ABC-type Fe3 transport system permease component
ANH9381_RS08295	COG3842	ATPase activity
ANH9381_RS08300	COG3101	peptidyl-lysine hydroxylation
ANH9381_RS08305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANH9381_RS08315	COG0788	formyltetrahydrofolate deformylase activity
ANH9381_RS08320	COG2916	Histone family protein nucleoid-structuring protein H-NS
ANH9381_RS08325	COG1757	Na H antiporter
ANH9381_RS08360	COG3161	chorismate lyase activity
ANH9381_RS08370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ANH9381_RS08375	COG1758	RNA polymerase activity
ANH9381_RS08385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ANH9381_RS08405	COG2850	peptidyl-arginine hydroxylation
ANH9381_RS08420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_RS08425	COG1137	ATPase activity
ANH9381_RS08430	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ANH9381_RS08435	COG3117	lipopolysaccharide transmembrane transporter activity
ANH9381_RS08440	COG1127	ABC transporter
ANH9381_RS08445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ANH9381_RS08450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ANH9381_RS08455	COG2854	intermembrane phospholipid transfer
ANH9381_RS08460	COG3113	response to antibiotic
ANH9381_RS08465	COG5007	Belongs to the BolA IbaG family
ANH9381_RS08480	COG0463	Glycosyl transferase, family 2
ANH9381_RS08490	COG3691	Protein conserved in bacteria
ANH9381_RS08495	COG2067	long-chain fatty acid transport protein
ANH9381_RS08500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ANH9381_RS08510	COG0861	Integral membrane protein TerC family
ANH9381_RS08530	COG1217	gtp-binding protein TYPA
ANH9381_RS08550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANH9381_RS08565	COG0517	IMP dehydrogenase activity
ANH9381_RS08565	COG1125	glycine betaine transport
ANH9381_RS08570	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ANH9381_RS08595	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ANH9381_RS08600	COG2091	lysine biosynthetic process via aminoadipic acid
ANH9381_RS08610	COG0330	HflC and HflK could
ANH9381_RS08615	COG1555	photosystem II stabilization
ANH9381_RS08620	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ANH9381_RS08630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANH9381_RS08635	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ANH9381_RS08640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANH9381_RS08645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ANH9381_RS08650	COG0800	Aldolase
ANH9381_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
ANH9381_RS08665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANH9381_RS08675	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ANH9381_RS08690	COG2186	Transcriptional regulator
ANH9381_RS08715	COG0659	secondary active sulfate transmembrane transporter activity
ANH9381_RS08725	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ANH9381_RS08740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ANH9381_RS08745	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ANH9381_RS08765	COG3115	cell septum assembly
ANH9381_RS08775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ANH9381_RS08780	COG1573	uracil-dna glycosylase
ANH9381_RS08785	COG0012	GTP binding
ANH9381_RS08790	COG0193	aminoacyl-tRNA hydrolase activity
ANH9381_RS08850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ANH9381_RS08855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ANH9381_RS08865	COG0024	Methionine aminopeptidase
ANH9381_RS08870	COG0316	Belongs to the HesB IscA family
ANH9381_RS08880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ANH9381_RS08885	COG0672	)-iron permease
ANH9381_RS08900	COG0577	efflux transmembrane transporter activity
ANH9381_RS08910	COG0577	efflux transmembrane transporter activity
ANH9381_RS08910	COG1136	(ABC) transporter
ANH9381_RS08915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANH9381_RS08925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANH9381_RS08930	COG3385	transposase activity
ANH9381_RS08945	COG1643	Atp-dependent helicase
ANH9381_RS08950	COG2363	Small membrane protein
ANH9381_RS08985	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ANH9381_RS08990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ANH9381_RS09000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANH9381_RS09005	COG1737	Transcriptional regulator
ANH9381_RS09015	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ANH9381_RS09020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANH9381_RS09030	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ANH9381_RS09035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANH9381_RS09035	COG2190	(PTS) system
ANH9381_RS09035	COG1263	PTS System
ANH9381_RS09055	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ANH9381_RS09060	COG3683	transport system, periplasmic component
ANH9381_RS09065	COG0488	(ABC) transporter
ANH9381_RS09075	COG0187	DNA topoisomerase II activity
ANH9381_RS09085	COG0625	glutathione transferase activity
ANH9381_RS09090	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ANH9381_RS09100	COG0251	oxidation-reduction process
ANH9381_RS09115	COG0463	Glycosyl transferase, family 2
ANH9381_RS09135	COG1560	Kdo2-lipid A biosynthetic process
ANH9381_RS09140	COG0730	response to heat
ANH9381_RS09145	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ANH9381_RS09150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ANH9381_RS09155	COG3264	Mechanosensitive ion channel
ANH9381_RS09155	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ANH9381_RS09160	COG0318	PFAM AMP-dependent synthetase and ligase
ANH9381_RS09165	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ANH9381_RS09170	COG0596	Alpha beta hydrolase
ANH9381_RS09175	COG0716	FMN binding
ANH9381_RS09180	COG0735	belongs to the Fur family
ANH9381_RS09185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANH9381_RS09190	COG3094	Invasion gene expression up-regulator, SirB
ANH9381_RS09195	COG0023	Translation Initiation Factor
ANH9381_RS09205	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ANH9381_RS09210	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ANH9381_RS09215	COG0776	regulation of translation
ANH9381_RS09220	COG0539	negative regulation of cytoplasmic translation
ANH9381_RS09230	COG2990	Protein conserved in bacteria
ANH9381_RS09235	COG4771	TonB-dependent receptor
ANH9381_RS09240	COG0612	Peptidase, M16
ANH9381_RS09245	COG1687	branched-chain amino acid
ANH9381_RS09250	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ANH9381_RS09255	COG0583	DNA-binding transcription factor activity
ANH9381_RS09285	COG2920	part of a sulfur-relay system
ANH9381_RS09295	COG1121	(ABC) transporter
ANH9381_RS09300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANH9381_RS09305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANH9381_RS09325	COG3304	Inner membrane component domain
ANH9381_RS09330	COG1289	transmembrane transporter activity
ANH9381_RS09345	COG3958	Transketolase
ANH9381_RS09350	COG3959	Transketolase, thiamine diphosphate binding domain
ANH9381_RS09370	COG0488	(ABC) transporter
ANH9381_RS09380	COG1346	cytolysis
ANH9381_RS09395	COG1525	nuclease
ANH9381_RS09400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANH9381_RS09405	COG2166	iron-sulfur cluster assembly
ANH9381_RS09410	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ANH9381_RS09410	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ANH9381_RS09415	COG1560	Kdo2-lipid A biosynthetic process
ANH9381_RS09420	COG3381	protein complex oligomerization
ANH9381_RS09425	COG2249	NAD(P)H dehydrogenase (quinone) activity
ANH9381_RS09435	COG0330	HflC and HflK could
ANH9381_RS09460	COG1858	cytochrome C peroxidase
ANH9381_RS09465	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ANH9381_RS09470	COG0318	PFAM AMP-dependent synthetase and ligase
ANH9381_RS09475	COG3065	identical protein binding
ANH9381_RS09480	COG1214	PFAM Peptidase M22, glycoprotease
ANH9381_RS09485	COG1199	ATP-dependent helicase activity
ANH9381_RS09490	COG0676	glucose-6-phosphate 1-epimerase activity
ANH9381_RS09495	COG3118	belongs to the thioredoxin family
ANH9381_RS09500	COG0492	ferredoxin-NADP+ reductase activity
ANH9381_RS09505	COG4988	ABC transporter
ANH9381_RS09510	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ANH9381_RS09515	COG1946	Acyl-CoA thioesterase
ANH9381_RS09520	COG0515	serine threonine protein kinase
ANH9381_RS09535	COG1940	carbohydrate kinase activity
ANH9381_RS09540	COG0671	phosphoesterase, PA-phosphatase related
ANH9381_RS09560	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ANH9381_RS09565	COG0708	Exodeoxyribonuclease III
ANH9381_RS09595	COG1216	Glycosyl transferase, family 2
ANH9381_RS09600	COG2246	polysaccharide biosynthetic process
ANH9381_RS09625	COG0463	Glycosyl transferase, family 2
ANH9381_RS09660	COG2951	lytic endotransglycosylase activity
ANH9381_RS09665	COG1216	Glycosyl transferase, family 2
ANH9381_RS09670	COG1216	Glycosyl transferase, family 2
ANH9381_RS09680	COG3306	glycosyltransferase involved in LPS biosynthesis
ANH9381_RS09690	COG5039	Polysaccharide pyruvyl transferase
ANH9381_RS09695	COG2161	toxin-antitoxin pair type II binding
ANH9381_RS09700	COG4115	mRNA cleavage
ANH9381_RS09705	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ANH9381_RS09710	COG1793	dna ligase
ANH9381_RS09730	COG1609	Transcriptional regulator
ANH9381_RS09750	COG0437	4 iron, 4 sulfur cluster binding
ANH9381_RS09755	COG2864	formate dehydrogenase
ANH9381_RS09760	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ANH9381_RS09765	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANH9381_RS09770	COG0651	ATP synthesis coupled electron transport
ANH9381_RS09775	COG0650	Formate hydrogenlyase subunit 4
ANH9381_RS09780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ANH9381_RS09785	COG4237	Hydrogenase 4 membrane
ANH9381_RS09790	COG0651	ATP synthesis coupled electron transport
ANH9381_RS09795	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ANH9381_RS09795	COG3261	NADH dehydrogenase
ANH9381_RS09800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANH9381_RS09805	COG3260	NADH ubiquinone oxidoreductase 20
ANH9381_RS09815	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ANH9381_RS09820	COG3383	formate dehydrogenase (NAD+) activity
ANH9381_RS09825	COG3383	formate dehydrogenase (NAD+) activity
ANH9381_RS09830	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ANH9381_RS09840	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANH9381_RS09845	COG0567	Dehydrogenase, E1 component
ANH9381_RS09850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANH9381_RS09855	COG3108	Peptidase M15
ANH9381_RS09860	COG2989	Protein conserved in bacteria
ANH9381_RS09870	COG0793	Belongs to the peptidase S41A family
ANH9381_RS09880	COG2995	paraquat-inducible protein a
ANH9381_RS09885	COG3008	intermembrane lipid transfer
ANH9381_RS09895	COG3842	ATPase activity
ANH9381_RS09900	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANH9381_RS09905	COG1177	transmembrane transport
ANH9381_RS09910	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ANH9381_RS09925	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ANH9381_RS09930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ANH9381_RS09945	COG1522	sequence-specific DNA binding
ANH9381_RS09950	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ANH9381_RS09955	COG3025	triphosphatase activity
ANH9381_RS09960	COG1392	Phosphate transport regulator
ANH9381_RS09965	COG0306	phosphate transporter
ANH9381_RS09970	COG4991	sh3 domain protein
ANH9381_RS09975	COG0617	tRNA 3'-terminal CCA addition
ANH9381_RS09980	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ANH9381_RS09985	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ANH9381_RS10000	COG1620	l-lactate permease
ANH9381_RS10020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ANH9381_RS10025	COG0328	RNA-DNA hybrid ribonuclease activity
ANH9381_RS10030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ANH9381_RS10050	COG2026	Addiction module toxin, RelE StbE family
ANH9381_RS10065	COG0826	peptidase U32
ANH9381_RS10085	COG1862	Preprotein translocase
ANH9381_RS10090	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANH9381_RS10095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANH9381_RS10105	COG1012	belongs to the aldehyde dehydrogenase family
ANH9381_RS10105	COG1454	alcohol dehydrogenase
ANH9381_RS10110	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANH9381_RS10115	COG1129	ABC transporter
ANH9381_RS10130	COG0673	inositol 2-dehydrogenase activity
ANH9381_RS10140	COG2271	Major facilitator Superfamily
ANH9381_RS10150	COG3718	enzyme involved in inositol metabolism
ANH9381_RS10160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANH9381_RS10165	COG3962	Belongs to the TPP enzyme family
ANH9381_RS10175	COG0673	inositol 2-dehydrogenase activity
ANH9381_RS10180	COG3722	fumarate hydratase activity
ANH9381_RS10185	COG0246	Mannitol dehydrogenase
ANH9381_RS10195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANH9381_RS10200	COG2274	protein secretion by the type I secretion system
ANH9381_RS10205	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ANH9381_RS10210	COG2994	toxin metabolic process
ANH9381_RS10220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ANH9381_RS10235	COG2813	Specifically methylates the guanine in position
ANH9381_RS10240	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ANH9381_RS10245	COG0456	acetyltransferase
ANH9381_RS10250	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ANH9381_RS10335	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANH9381_RS10335	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system