locus-tag	class	description
NT05HA_RS00020	COG0252	asparaginase activity
NT05HA_RS00035	COG3063	Type IV pilus biogenesis stability protein PilW
NT05HA_RS00040	COG1426	Protein conserved in bacteria
NT05HA_RS00055	COG2976	Protein conserved in bacteria
NT05HA_RS00065	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NT05HA_RS00070	COG2233	PERMEase
NT05HA_RS00080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NT05HA_RS00085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NT05HA_RS00095	COG0659	secondary active sulfate transmembrane transporter activity
NT05HA_RS00100	COG0800	Aldolase
NT05HA_RS00110	COG0281	malic enzyme
NT05HA_RS00110	COG0280	phosphate acetyltransferase
NT05HA_RS00120	COG2814	Major facilitator Superfamily
NT05HA_RS00125	COG4133	protoheme IX ABC transporter activity
NT05HA_RS00130	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NT05HA_RS00135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NT05HA_RS00140	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NT05HA_RS00150	COG1138	Cytochrome C-type biogenesis protein
NT05HA_RS00155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NT05HA_RS00185	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NT05HA_RS00190	COG0437	4 iron, 4 sulfur cluster binding
NT05HA_RS00195	COG3301	Polysulphide reductase, NrfD
NT05HA_RS00200	COG1138	Cytochrome C-type biogenesis protein
NT05HA_RS00205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NT05HA_RS00210	COG4235	cytochrome complex assembly
NT05HA_RS00210	COG3088	subunit of a heme lyase
NT05HA_RS00215	COG2081	HI0933 family
NT05HA_RS00220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NT05HA_RS00225	COG1305	Transglutaminase-like
NT05HA_RS00235	COG2608	mercury ion transmembrane transporter activity
NT05HA_RS00245	COG2226	methyltransferase
NT05HA_RS00255	COG0592	DNA-directed DNA polymerase activity
NT05HA_RS00285	COG0602	queuosine metabolic process
NT05HA_RS00290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NT05HA_RS00290	COG1328	CTP reductase activity
NT05HA_RS00300	COG1022	Amp-dependent synthetase and ligase
NT05HA_RS00305	COG0587	DNA-directed DNA polymerase activity
NT05HA_RS00310	COG0121	glutamine amidotransferase
NT05HA_RS00315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NT05HA_RS00345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NT05HA_RS00360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NT05HA_RS00365	COG0494	nUDIX hydrolase
NT05HA_RS00370	COG0730	response to heat
NT05HA_RS00380	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NT05HA_RS00385	COG0590	tRNA wobble adenosine to inosine editing
NT05HA_RS00390	COG3078	GTPase activator activity
NT05HA_RS00400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NT05HA_RS00405	COG0456	acetyltransferase
NT05HA_RS00410	COG0149	triose-phosphate isomerase activity
NT05HA_RS00415	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NT05HA_RS00430	COG0511	ligase activity, forming carbon-carbon bonds
NT05HA_RS00435	COG0439	Biotin carboxylase
NT05HA_RS00455	COG0681	Belongs to the peptidase S26 family
NT05HA_RS00470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NT05HA_RS00485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NT05HA_RS00495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NT05HA_RS00510	COG0537	adenosine 5'-monophosphoramidase activity
NT05HA_RS00515	COG2116	formate transmembrane transporter activity
NT05HA_RS00520	COG1882	Formate acetyltransferase
NT05HA_RS00530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NT05HA_RS00535	COG0697	spore germination
NT05HA_RS00545	COG0204	Acyl-transferase
NT05HA_RS00555	COG5413	integral membrane protein
NT05HA_RS00560	COG2964	Protein conserved in bacteria
NT05HA_RS00565	COG0814	amino acid
NT05HA_RS00570	COG3033	Beta-eliminating lyase
NT05HA_RS00580	COG1509	lysine 2,3-aminomutase activity
NT05HA_RS00585	COG3061	Opacity-associated protein A
NT05HA_RS00585	COG3266	domain, Protein
NT05HA_RS00600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NT05HA_RS00605	COG2814	Major facilitator Superfamily
NT05HA_RS00610	COG4974	Belongs to the 'phage' integrase family
NT05HA_RS00620	COG0330	HflC and HflK could
NT05HA_RS00625	COG0330	HflC and HflK could
NT05HA_RS00635	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NT05HA_RS00670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NT05HA_RS00675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NT05HA_RS00695	COG1217	gtp-binding protein TYPA
NT05HA_RS00700	COG0174	glutamine synthetase
NT05HA_RS00705	COG0861	Integral membrane protein TerC family
NT05HA_RS00715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NT05HA_RS00725	COG3691	Protein conserved in bacteria
NT05HA_RS00730	COG0471	metal ion transport
NT05HA_RS00735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NT05HA_RS00740	COG1575	Belongs to the MenA family. Type 1 subfamily
NT05HA_RS00745	COG1720	tRNA m6t6A37 methyltransferase activity
NT05HA_RS00750	COG0789	Transcriptional regulator
NT05HA_RS00755	COG2608	mercury ion transmembrane transporter activity
NT05HA_RS00760	COG2217	Heavy metal translocating P-type atpase
NT05HA_RS00765	COG3739	integral membrane protein
NT05HA_RS00775	COG0740	serine-type endopeptidase activity
NT05HA_RS00790	COG2918	glutathione biosynthetic process
NT05HA_RS00790	COG1181	Belongs to the D-alanine--D-alanine ligase family
NT05HA_RS00840	COG4964	Belongs to the GSP D family
NT05HA_RS00865	COG1702	phosphate starvation-inducible protein PhoH
NT05HA_RS00870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NT05HA_RS00880	COG1444	tRNA N-acetyltransferase activity
NT05HA_RS00885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NT05HA_RS00905	COG1126	abc transporter atp-binding protein
NT05HA_RS00910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NT05HA_RS00915	COG4215	(ABC) transporter
NT05HA_RS00920	COG4160	amino acid transport
NT05HA_RS00935	COG1966	Carbon starvation protein
NT05HA_RS00950	COG3116	cell division
NT05HA_RS00955	COG0768	penicillin binding
NT05HA_RS00960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NT05HA_RS00965	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NT05HA_RS00985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NT05HA_RS01000	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NT05HA_RS01005	COG0849	cell division
NT05HA_RS01010	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NT05HA_RS01020	COG1605	Chorismate mutase
NT05HA_RS01020	COG0077	Prephenate dehydratase
NT05HA_RS01030	COG0326	Molecular chaperone. Has ATPase activity
NT05HA_RS01035	COG1393	Belongs to the ArsC family
NT05HA_RS01050	COG1876	peptidase activity
NT05HA_RS01055	COG0494	nUDIX hydrolase
NT05HA_RS01060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NT05HA_RS01075	COG0826	peptidase U32
NT05HA_RS01090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NT05HA_RS01100	COG0471	metal ion transport
NT05HA_RS01105	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NT05HA_RS01105	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
NT05HA_RS01110	COG3051	citrate lyase alpha subunit
NT05HA_RS01115	COG2301	Belongs to the HpcH HpaI aldolase family
NT05HA_RS01125	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NT05HA_RS01130	COG4535	Mg2 and Co2 transporter CorC
NT05HA_RS01150	COG0105	UTP biosynthetic process
NT05HA_RS01155	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NT05HA_RS01170	COG3501	Rhs element vgr protein
NT05HA_RS01180	COG3209	COG3209 Rhs family protein
NT05HA_RS01205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NT05HA_RS01210	COG1530	ribonuclease E activity
NT05HA_RS01215	COG2999	glutathione oxidoreductase activity
NT05HA_RS01220	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NT05HA_RS01230	COG0725	ABC transporter, periplasmic molybdate-binding protein
NT05HA_RS01235	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NT05HA_RS01240	COG3842	ATPase activity
NT05HA_RS01245	COG0157	Belongs to the NadC ModD family
NT05HA_RS01260	COG4953	penicillin-binding protein 1C
NT05HA_RS01300	COG3501	Rhs element vgr protein
NT05HA_RS01330	COG1823	symporter activity
NT05HA_RS01340	COG0795	lipopolysaccharide-transporting ATPase activity
NT05HA_RS01345	COG0795	lipopolysaccharide-transporting ATPase activity
NT05HA_RS01350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NT05HA_RS01355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NT05HA_RS01365	COG0739	heme binding
NT05HA_RS01370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NT05HA_RS01390	COG0617	tRNA 3'-terminal CCA addition
NT05HA_RS01395	COG4991	sh3 domain protein
NT05HA_RS01400	COG0306	phosphate transporter
NT05HA_RS01410	COG3025	triphosphatase activity
NT05HA_RS01415	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NT05HA_RS01420	COG1522	sequence-specific DNA binding
NT05HA_RS01440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NT05HA_RS01445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NT05HA_RS01495	COG1518	maintenance of DNA repeat elements
NT05HA_RS01505	COG2190	(PTS) system
NT05HA_RS01505	COG1263	PTS System
NT05HA_RS01505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NT05HA_RS01515	COG0058	SHG alpha-glucan phosphorylase activity
NT05HA_RS01520	COG2188	Transcriptional regulator
NT05HA_RS01535	COG0583	DNA-binding transcription factor activity
NT05HA_RS01540	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NT05HA_RS01545	COG1687	branched-chain amino acid
NT05HA_RS01550	COG0612	Peptidase, M16
NT05HA_RS01555	COG4771	TonB-dependent receptor
NT05HA_RS01560	COG2990	Protein conserved in bacteria
NT05HA_RS01565	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NT05HA_RS01570	COG0539	negative regulation of cytoplasmic translation
NT05HA_RS01575	COG0776	regulation of translation
NT05HA_RS01580	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
NT05HA_RS01585	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NT05HA_RS01595	COG0023	Translation Initiation Factor
NT05HA_RS01600	COG3094	Invasion gene expression up-regulator, SirB
NT05HA_RS01605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NT05HA_RS01615	COG0735	belongs to the Fur family
NT05HA_RS01620	COG0716	FMN binding
NT05HA_RS01630	COG0596	Alpha beta hydrolase
NT05HA_RS01635	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
NT05HA_RS01640	COG0318	PFAM AMP-dependent synthetase and ligase
NT05HA_RS01645	COG3264	Mechanosensitive ion channel
NT05HA_RS01645	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NT05HA_RS01655	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
NT05HA_RS01660	COG0730	response to heat
NT05HA_RS01665	COG1560	Kdo2-lipid A biosynthetic process
NT05HA_RS01675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NT05HA_RS01680	COG3021	interspecies interaction between organisms
NT05HA_RS01685	COG0251	oxidation-reduction process
NT05HA_RS01705	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NT05HA_RS01710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NT05HA_RS01715	COG0602	queuosine metabolic process
NT05HA_RS01720	COG0720	synthase
NT05HA_RS01750	COG1289	transmembrane transporter activity
NT05HA_RS01755	COG3304	Inner membrane component domain
NT05HA_RS01775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NT05HA_RS01780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NT05HA_RS01785	COG1121	(ABC) transporter
NT05HA_RS01795	COG2920	part of a sulfur-relay system
NT05HA_RS01805	COG3105	Protein conserved in bacteria
NT05HA_RS01815	COG1944	ATP diphosphatase activity
NT05HA_RS01830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NT05HA_RS01830	COG2190	(PTS) system
NT05HA_RS01830	COG1263	PTS System
NT05HA_RS01835	COG2226	methyltransferase
NT05HA_RS01850	COG1940	carbohydrate kinase activity
NT05HA_RS01850	COG1846	Transcriptional regulator
NT05HA_RS01875	COG0405	Gamma-glutamyltransferase
NT05HA_RS01890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NT05HA_RS01905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NT05HA_RS01915	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NT05HA_RS01920	COG1177	transmembrane transport
NT05HA_RS01925	COG1176	ABC-type spermidine putrescine transport system, permease component I
NT05HA_RS01930	COG3842	ATPase activity
NT05HA_RS01940	COG3008	intermembrane lipid transfer
NT05HA_RS01945	COG2995	paraquat-inducible protein a
NT05HA_RS01960	COG2989	Protein conserved in bacteria
NT05HA_RS01965	COG3108	Peptidase M15
NT05HA_RS01970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NT05HA_RS01975	COG0567	Dehydrogenase, E1 component
NT05HA_RS01980	COG0508	dehydrogenase complex catalyzes the overall conversion of
NT05HA_RS01990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NT05HA_RS02020	COG3070	regulator of competence-specific genes
NT05HA_RS02040	COG0745	RESPONSE REGULATOR receiver
NT05HA_RS02045	COG0642	Histidine kinase
NT05HA_RS02055	COG2814	Major facilitator Superfamily
NT05HA_RS02060	COG0375	protein maturation
NT05HA_RS02070	COG2252	PERMEase
NT05HA_RS02085	COG0825	malonyl-CoA metabolic process
NT05HA_RS02200	COG1802	Transcriptional regulator
NT05HA_RS02200	COG4626	Terminase
NT05HA_RS02380	COG0582	viral genome integration into host DNA
NT05HA_RS02395	COG3069	C4-dicarboxylate transmembrane transporter activity
NT05HA_RS02400	COG2233	PERMEase
NT05HA_RS02420	COG0516	GMP reductase activity
NT05HA_RS02420	COG0517	IMP dehydrogenase activity
NT05HA_RS02425	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NT05HA_RS02425	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NT05HA_RS02435	COG0351	phosphomethylpyrimidine kinase
NT05HA_RS02440	COG4143	(ABC) transporter
NT05HA_RS02445	COG1178	ABC-type Fe3 transport system permease component
NT05HA_RS02450	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NT05HA_RS02475	COG1263	PTS System
NT05HA_RS02475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NT05HA_RS02475	COG2190	(PTS) system
NT05HA_RS02485	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NT05HA_RS02485	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NT05HA_RS02490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NT05HA_RS02495	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NT05HA_RS02505	COG1737	Transcriptional regulator
NT05HA_RS02510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NT05HA_RS02515	COG0363	glucosamine-6-phosphate deaminase activity
NT05HA_RS02520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NT05HA_RS02525	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NT05HA_RS02540	COG0247	lactate metabolic process
NT05HA_RS02540	COG0277	FAD linked oxidase domain protein
NT05HA_RS02550	COG1704	LemA family
NT05HA_RS02575	COG2363	Small membrane protein
NT05HA_RS02580	COG1643	Atp-dependent helicase
NT05HA_RS02595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NT05HA_RS02600	COG0577	efflux transmembrane transporter activity
NT05HA_RS02600	COG1136	(ABC) transporter
NT05HA_RS02610	COG0577	efflux transmembrane transporter activity
NT05HA_RS02625	COG0672	)-iron permease
NT05HA_RS02630	COG1556	Lactate utilization protein
NT05HA_RS02640	COG0247	lactate metabolic process
NT05HA_RS02645	COG1620	l-lactate permease
NT05HA_RS02650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NT05HA_RS02655	COG3112	Uncharacterised protein family (UPF0231)
NT05HA_RS02660	COG0316	Belongs to the HesB IscA family
NT05HA_RS02665	COG0024	Methionine aminopeptidase
NT05HA_RS02675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NT05HA_RS02680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NT05HA_RS02725	COG3787	Belongs to the UPF0306 family
NT05HA_RS02730	COG4172	Belongs to the ABC transporter superfamily
NT05HA_RS02735	COG4172	Belongs to the ABC transporter superfamily
NT05HA_RS02740	COG4171	peptide transport system, permease
NT05HA_RS02745	COG4168	peptide transport system, permease
NT05HA_RS02755	COG1120	ATPase activity
NT05HA_RS02765	COG3106	COG3106 Predicted ATPase
NT05HA_RS02775	COG3283	Transcriptional regulator of aromatic amino acids metabolism
NT05HA_RS02795	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NT05HA_RS02800	COG0860	N-Acetylmuramoyl-L-alanine amidase
NT05HA_RS02800	COG1388	LysM domain
NT05HA_RS02805	COG0802	atpase or kinase
NT05HA_RS02825	COG1162	GTPase activity
NT05HA_RS02830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NT05HA_RS02835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NT05HA_RS02840	COG2190	(PTS) system
NT05HA_RS02845	COG0339	signal peptide processing
NT05HA_RS02850	COG2832	Protein of unknown function (DUF454)
NT05HA_RS02855	COG4166	transmembrane transport
NT05HA_RS02870	COG0671	phosphoesterase, PA-phosphatase related
NT05HA_RS02875	COG1940	carbohydrate kinase activity
NT05HA_RS02880	COG1216	Glycosyl transferase, family 2
NT05HA_RS02885	COG2951	lytic endotransglycosylase activity
NT05HA_RS02900	COG2246	polysaccharide biosynthetic process
NT05HA_RS02935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NT05HA_RS02940	COG0708	Exodeoxyribonuclease III
NT05HA_RS02945	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NT05HA_RS02950	COG1088	dTDP-glucose 4,6-dehydratase activity
NT05HA_RS02960	COG0778	Nitroreductase
NT05HA_RS02965	COG0616	signal peptide processing
NT05HA_RS02970	COG1605	Chorismate mutase
NT05HA_RS02970	COG0287	Prephenate dehydrogenase
NT05HA_RS02975	COG0009	L-threonylcarbamoyladenylate synthase
NT05HA_RS02985	COG0583	DNA-binding transcription factor activity
NT05HA_RS02995	COG2351	hydroxyisourate hydrolase activity
NT05HA_RS03005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NT05HA_RS03010	COG0508	dehydrogenase complex catalyzes the overall conversion of
NT05HA_RS03015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NT05HA_RS03025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NT05HA_RS03035	COG0512	Glutamine amidotransferase of anthranilate synthase
NT05HA_RS03040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NT05HA_RS03055	COG1943	Transposase
NT05HA_RS03060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT05HA_RS03095	COG4591	ABC-type transport system involved in lipoprotein release permease component
NT05HA_RS03100	COG1136	(ABC) transporter
NT05HA_RS03105	COG4591	ABC-type transport system involved in lipoprotein release permease component
NT05HA_RS03115	COG0305	Participates in initiation and elongation during chromosome replication
NT05HA_RS03130	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NT05HA_RS03140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NT05HA_RS03145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NT05HA_RS03150	COG1280	lysine exporter protein (LysE YggA)
NT05HA_RS03160	COG0633	Ferredoxin
NT05HA_RS03165	COG0471	metal ion transport
NT05HA_RS03170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NT05HA_RS03175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NT05HA_RS03180	COG1840	ABC-type Fe3 transport system, periplasmic component
NT05HA_RS03190	COG3842	ATPase activity
NT05HA_RS03205	COG3955	Domain of unknown function (DUF1919)
NT05HA_RS03210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NT05HA_RS03215	COG0785	Cytochrome C biogenesis protein
NT05HA_RS03220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NT05HA_RS03220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NT05HA_RS03225	COG0288	reversible hydration of carbon dioxide
NT05HA_RS03230	COG2823	Periplasmic or secreted lipoprotein
NT05HA_RS03235	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NT05HA_RS03250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NT05HA_RS03255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NT05HA_RS03260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NT05HA_RS03275	COG0616	signal peptide processing
NT05HA_RS03305	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NT05HA_RS03310	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NT05HA_RS03315	COG3738	Protein conserved in bacteria
NT05HA_RS03325	COG0142	geranyltranstransferase activity
NT05HA_RS03340	COG2819	hydrolase of the alpha beta superfamily
NT05HA_RS03350	COG0285	dihydrofolate synthase activity
NT05HA_RS03355	COG0588	phosphoglycerate mutase activity
NT05HA_RS03360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NT05HA_RS03365	COG2431	L-lysine efflux transmembrane transporter activity
NT05HA_RS03370	COG0564	pseudouridine synthase activity
NT05HA_RS03380	COG2824	Alkylphosphonate utilization operon protein PhnA
NT05HA_RS03405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NT05HA_RS03430	COG1523	belongs to the glycosyl hydrolase 13 family
NT05HA_RS03445	COG0058	SHG alpha-glucan phosphorylase activity
NT05HA_RS03455	COG0586	Pfam SNARE associated Golgi protein
NT05HA_RS03470	COG1686	Belongs to the peptidase S11 family
NT05HA_RS03475	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
NT05HA_RS03490	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
NT05HA_RS03495	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NT05HA_RS03500	COG0697	spore germination
NT05HA_RS03505	COG2925	Exonuclease
NT05HA_RS03510	COG1528	Iron-storage protein
NT05HA_RS03515	COG1528	Iron-storage protein
NT05HA_RS03520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NT05HA_RS03525	COG0589	response to stress
NT05HA_RS03530	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
NT05HA_RS03540	COG0583	DNA-binding transcription factor activity
NT05HA_RS03545	COG0613	PHP domain protein
NT05HA_RS03560	COG0308	aminopeptidase N
NT05HA_RS03565	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NT05HA_RS03570	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NT05HA_RS03575	COG1448	Aminotransferase
NT05HA_RS03580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT05HA_RS03585	COG1120	ATPase activity
NT05HA_RS03595	COG3585	molybdate ion transport
NT05HA_RS03600	COG1309	transcriptional regulator
NT05HA_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NT05HA_RS03615	COG0842	Transport permease protein
NT05HA_RS03620	COG1538	Outer membrane efflux protein
NT05HA_RS03640	COG0791	NLP P60 protein
NT05HA_RS03655	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NT05HA_RS03670	COG0517	IMP dehydrogenase activity
NT05HA_RS03670	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NT05HA_RS03675	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NT05HA_RS03685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NT05HA_RS03690	COG0512	Glutamine amidotransferase of anthranilate synthase
NT05HA_RS03695	COG1942	4-Oxalocrotonate Tautomerase
NT05HA_RS03705	COG0134	indole-3-glycerol-phosphate synthase activity
NT05HA_RS03705	COG0135	phosphoribosylanthranilate isomerase activity
NT05HA_RS03710	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NT05HA_RS03715	COG0437	4 iron, 4 sulfur cluster binding
NT05HA_RS03720	COG5557	Pfam Polysulphide reductase, NrfD
NT05HA_RS03725	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NT05HA_RS03730	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NT05HA_RS03735	COG1773	rubredoxin
NT05HA_RS03740	COG0298	carbon dioxide binding
NT05HA_RS03750	COG3630	sodium ion export across plasma membrane
NT05HA_RS03755	COG0511	ligase activity, forming carbon-carbon bonds
NT05HA_RS03755	COG5016	pyruvate
NT05HA_RS03765	COG4221	oxidoreductase activity
NT05HA_RS03770	COG0133	tryptophan synthase activity
NT05HA_RS03780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NT05HA_RS03790	COG0469	pyruvate kinase activity
NT05HA_RS03805	COG1879	ABC-type sugar transport system periplasmic component
NT05HA_RS03825	COG2390	Transcriptional regulator
NT05HA_RS03850	COG2969	positive regulation of protein catabolic process
NT05HA_RS03860	COG0314	molybdopterin synthase activity
NT05HA_RS03865	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NT05HA_RS03875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NT05HA_RS03900	COG3005	denitrification pathway
NT05HA_RS03910	COG3005	denitrification pathway
NT05HA_RS03915	COG0243	molybdopterin cofactor binding
NT05HA_RS03920	COG2315	Protein conserved in bacteria
NT05HA_RS03925	COG0366	Alpha amylase catalytic
NT05HA_RS03930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NT05HA_RS03930	COG1263	PTS System
NT05HA_RS03935	COG0101	tRNA pseudouridine synthase activity
NT05HA_RS03955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NT05HA_RS03960	COG1074	ATP-dependent DNA helicase activity
NT05HA_RS03965	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NT05HA_RS03970	COG2252	PERMEase
NT05HA_RS03980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NT05HA_RS03985	COG1067	ATP-dependent peptidase activity
NT05HA_RS03995	COG1278	Cold shock
NT05HA_RS04010	COG3098	single-species biofilm formation
NT05HA_RS04015	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
NT05HA_RS04020	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NT05HA_RS04020	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NT05HA_RS04025	COG3101	peptidyl-lysine hydroxylation
NT05HA_RS04030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NT05HA_RS04040	COG0788	formyltetrahydrofolate deformylase activity
NT05HA_RS04045	COG2916	Histone family protein nucleoid-structuring protein H-NS
NT05HA_RS04050	COG1757	Na H antiporter
NT05HA_RS04085	COG2949	membrane
NT05HA_RS04090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NT05HA_RS04105	COG3099	Belongs to the UPF0263 family
NT05HA_RS04110	COG4178	(ABC) transporter
NT05HA_RS04115	COG4774	siderophore transport
NT05HA_RS04125	COG0307	riboflavin synthase, alpha
NT05HA_RS04130	COG1534	Rna-binding protein
NT05HA_RS04135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NT05HA_RS04140	COG2027	D-alanyl-D-alanine carboxypeptidase
NT05HA_RS04150	COG0303	'Molybdopterin
NT05HA_RS04155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NT05HA_RS04165	COG4580	involved in the transport of maltose and maltodextrins
NT05HA_RS04175	COG3842	ATPase activity
NT05HA_RS04180	COG2182	Extracellular solute-binding protein
NT05HA_RS04185	COG2182	Extracellular solute-binding protein
NT05HA_RS04195	COG3833	ABC-type maltose transport systems, permease component
NT05HA_RS04200	COG0366	Alpha amylase catalytic
NT05HA_RS04270	COG2909	trisaccharide binding
NT05HA_RS04275	COG0058	SHG alpha-glucan phosphorylase activity
NT05HA_RS04280	COG1640	4-alpha-glucanotransferase
NT05HA_RS04290	COG0163	prenyltransferase activity
NT05HA_RS04300	COG1286	toxin biosynthetic process
NT05HA_RS04310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NT05HA_RS04315	COG0857	belongs to the CobB CobQ family
NT05HA_RS04315	COG0280	phosphate acetyltransferase
NT05HA_RS04330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NT05HA_RS04335	COG0617	tRNA 3'-terminal CCA addition
NT05HA_RS04340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NT05HA_RS04345	COG2333	competence protein COMEC
NT05HA_RS04345	COG0658	competence protein
NT05HA_RS04350	COG1132	(ABC) transporter
NT05HA_RS04355	COG1663	tetraacyldisaccharide 4'-kinase activity
NT05HA_RS04360	COG2835	tetraacyldisaccharide 4'-kinase activity
NT05HA_RS04370	COG0322	excinuclease ABC activity
NT05HA_RS04400	COG1176	ABC-type spermidine putrescine transport system, permease component I
NT05HA_RS04405	COG1175	transmembrane transport
NT05HA_RS04410	COG3842	ATPase activity
NT05HA_RS04420	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NT05HA_RS04425	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NT05HA_RS04440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NT05HA_RS04445	COG1621	beta-fructofuranosidase activity
NT05HA_RS04460	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NT05HA_RS04470	COG0195	Participates in both transcription termination and antitermination
NT05HA_RS04485	COG3100	YcgL domain-containing protein
NT05HA_RS04500	COG2062	phosphohistidine phosphatase, SixA
NT05HA_RS04510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NT05HA_RS04515	COG2962	Rard protein
NT05HA_RS04520	COG1522	sequence-specific DNA binding
NT05HA_RS04525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NT05HA_RS04540	COG2932	Transcriptional regulator
NT05HA_RS04550	COG2801	Transposase and inactivated derivatives
NT05HA_RS04555	COG0791	NLP P60 protein
NT05HA_RS04565	COG2890	protein-(glutamine-N5) methyltransferase activity
NT05HA_RS04575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NT05HA_RS04580	COG3133	Outer membrane lipoprotein
NT05HA_RS04595	COG5339	Protein conserved in bacteria
NT05HA_RS04600	COG0443	Heat shock 70 kDa protein
NT05HA_RS04605	COG1403	HNH endonuclease
NT05HA_RS04610	COG0484	heat shock protein binding
NT05HA_RS04620	COG0626	cystathionine gamma-synthase activity
NT05HA_RS04625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NT05HA_RS04645	COG0305	Participates in initiation and elongation during chromosome replication
NT05HA_RS04710	COG0629	single-stranded DNA binding
NT05HA_RS04755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NT05HA_RS04765	COG3219	Protein conserved in bacteria
NT05HA_RS04770	COG3220	belongs to the UPF0276 family
NT05HA_RS04780	COG2259	Doxx family
NT05HA_RS04835	COG1858	cytochrome C peroxidase
NT05HA_RS04840	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NT05HA_RS04845	COG0318	PFAM AMP-dependent synthetase and ligase
NT05HA_RS04850	COG3065	identical protein binding
NT05HA_RS04855	COG1214	PFAM Peptidase M22, glycoprotease
NT05HA_RS04860	COG1199	ATP-dependent helicase activity
NT05HA_RS04865	COG0676	glucose-6-phosphate 1-epimerase activity
NT05HA_RS04875	COG1174	glycine betaine transport
NT05HA_RS04880	COG1125	glycine betaine transport
NT05HA_RS04880	COG0517	IMP dehydrogenase activity
NT05HA_RS04890	COG3118	belongs to the thioredoxin family
NT05HA_RS04895	COG0492	ferredoxin-NADP+ reductase activity
NT05HA_RS04905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NT05HA_RS04910	COG1946	Acyl-CoA thioesterase
NT05HA_RS04915	COG0515	serine threonine protein kinase
NT05HA_RS04930	COG1216	Glycosyl transferase, family 2
NT05HA_RS04940	COG3306	glycosyltransferase involved in LPS biosynthesis
NT05HA_RS04950	COG5039	Polysaccharide pyruvyl transferase
NT05HA_RS04955	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NT05HA_RS04960	COG1793	dna ligase
NT05HA_RS04970	COG0210	DNA helicase
NT05HA_RS04975	COG2610	gluconate transmembrane transporter activity
NT05HA_RS04980	COG3265	gluconokinase activity
NT05HA_RS04985	COG1609	Transcriptional regulator
NT05HA_RS05005	COG0437	4 iron, 4 sulfur cluster binding
NT05HA_RS05010	COG2864	formate dehydrogenase
NT05HA_RS05015	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NT05HA_RS05020	COG4149	molybdate abc transporter
NT05HA_RS05025	COG0725	ABC transporter, periplasmic molybdate-binding protein
NT05HA_RS05030	COG2005	Transcriptional regulator
NT05HA_RS05040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NT05HA_RS05045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NT05HA_RS05045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NT05HA_RS05050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NT05HA_RS05060	COG0583	DNA-binding transcription factor activity
NT05HA_RS05065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NT05HA_RS05075	COG1438	arginine binding
NT05HA_RS05080	COG1090	epimerase
NT05HA_RS05085	COG4657	Part of a membrane complex involved in electron transport
NT05HA_RS05095	COG4656	Part of a membrane complex involved in electron transport
NT05HA_RS05115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NT05HA_RS05125	COG3958	Transketolase
NT05HA_RS05130	COG3959	Transketolase, thiamine diphosphate binding domain
NT05HA_RS05145	COG0488	(ABC) transporter
NT05HA_RS05155	COG1346	cytolysis
NT05HA_RS05165	COG0425	Belongs to the sulfur carrier protein TusA family
NT05HA_RS05170	COG2391	methyltransferase activity
NT05HA_RS05180	COG1525	nuclease
NT05HA_RS05185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NT05HA_RS05190	COG2166	iron-sulfur cluster assembly
NT05HA_RS05195	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NT05HA_RS05195	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NT05HA_RS05200	COG1560	Kdo2-lipid A biosynthetic process
NT05HA_RS05205	COG3381	protein complex oligomerization
NT05HA_RS05210	COG2249	NAD(P)H dehydrogenase (quinone) activity
NT05HA_RS05220	COG0330	HflC and HflK could
NT05HA_RS05225	COG0737	Belongs to the 5'-nucleotidase family
NT05HA_RS05230	COG4771	TonB-dependent receptor
NT05HA_RS05230	COG1629	transport
NT05HA_RS05235	COG4607	ABC-type enterochelin transport system periplasmic component
NT05HA_RS05240	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT05HA_RS05245	COG4605	iron ion homeostasis
NT05HA_RS05250	COG4604	ABC transporter, ATP-binding protein
NT05HA_RS05255	COG3383	formate dehydrogenase (NAD+) activity
NT05HA_RS05260	COG3383	formate dehydrogenase (NAD+) activity
NT05HA_RS05270	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NT05HA_RS05280	COG3260	NADH ubiquinone oxidoreductase 20
NT05HA_RS05290	COG3261	NADH dehydrogenase
NT05HA_RS05290	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
NT05HA_RS05295	COG0651	ATP synthesis coupled electron transport
NT05HA_RS05300	COG4237	Hydrogenase 4 membrane
NT05HA_RS05305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NT05HA_RS05310	COG0650	Formate hydrogenlyase subunit 4
NT05HA_RS05315	COG0651	ATP synthesis coupled electron transport
NT05HA_RS05320	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NT05HA_RS05325	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NT05HA_RS05330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NT05HA_RS05350	COG0309	Hydrogenase expression formation protein (HypE)
NT05HA_RS05355	COG0409	Hydrogenase expression formation protein
NT05HA_RS05360	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NT05HA_RS05365	COG1122	ATPase activity
NT05HA_RS05370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NT05HA_RS05375	COG0310	cobalt ion transport
NT05HA_RS05380	COG0310	cobalt ion transport
NT05HA_RS05385	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
NT05HA_RS05390	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NT05HA_RS05395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NT05HA_RS05400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NT05HA_RS05405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NT05HA_RS05460	COG1840	ABC-type Fe3 transport system, periplasmic component
NT05HA_RS05465	COG1840	ABC-type Fe3 transport system, periplasmic component
NT05HA_RS05490	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NT05HA_RS05495	COG1959	2 iron, 2 sulfur cluster binding
NT05HA_RS05505	COG0822	iron-sulfur transferase activity
NT05HA_RS05515	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NT05HA_RS05520	COG0443	Heat shock 70 kDa protein
NT05HA_RS05525	COG0633	Ferredoxin
NT05HA_RS05530	COG2975	iron-sulfur cluster assembly
NT05HA_RS05535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NT05HA_RS05535	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NT05HA_RS05540	COG0489	protein tyrosine kinase activity
NT05HA_RS05545	COG3683	transport system, periplasmic component
NT05HA_RS05550	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
NT05HA_RS05565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NT05HA_RS05570	COG0488	(ABC) transporter
NT05HA_RS05580	COG0187	DNA topoisomerase II activity
NT05HA_RS05585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NT05HA_RS05590	COG0783	Belongs to the Dps family
NT05HA_RS05595	COG1566	PFAM secretion protein HlyD family protein
NT05HA_RS05600	COG2814	Major facilitator Superfamily
NT05HA_RS05605	COG1840	ABC-type Fe3 transport system, periplasmic component
NT05HA_RS05615	COG3550	peptidyl-serine autophosphorylation
NT05HA_RS05635	COG2927	DNA polymerase III (CHI subunit)
NT05HA_RS05640	COG0114	fumarate hydratase activity
NT05HA_RS05645	COG2268	Band 7 protein
NT05HA_RS05660	COG0778	Nitroreductase
NT05HA_RS05665	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NT05HA_RS05675	COG0814	amino acid
NT05HA_RS05685	COG0235	Class ii aldolase
NT05HA_RS05690	COG3623	hexulose-6-phosphate isomerase
NT05HA_RS05710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NT05HA_RS05715	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NT05HA_RS05745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NT05HA_RS05750	COG2017	converts alpha-aldose to the beta-anomer
NT05HA_RS05755	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NT05HA_RS05760	COG1085	galactose-1-phosphate uridylyltransferase
NT05HA_RS05765	COG1609	Transcriptional regulator
NT05HA_RS05770	COG1879	ABC-type sugar transport system periplasmic component
NT05HA_RS05775	COG1129	ABC transporter
NT05HA_RS05780	COG4211	Belongs to the binding-protein-dependent transport system permease family
NT05HA_RS05785	COG5002	protein histidine kinase activity
NT05HA_RS05785	COG2198	Histidine kinase
NT05HA_RS05785	COG0784	Response regulator, receiver
NT05HA_RS05790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NT05HA_RS05805	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NT05HA_RS05815	COG0497	DNA recombination
NT05HA_RS05830	COG1607	acyl-coa hydrolase
NT05HA_RS05835	COG2350	Protein conserved in bacteria
NT05HA_RS05840	COG0741	lytic transglycosylase activity
NT05HA_RS05850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NT05HA_RS05870	COG4133	protoheme IX ABC transporter activity
NT05HA_RS05885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NT05HA_RS05890	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NT05HA_RS05900	COG1408	metallophosphoesterase
NT05HA_RS05905	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NT05HA_RS05910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT05HA_RS05915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT05HA_RS05920	COG1120	ATPase activity
NT05HA_RS05930	COG1053	succinate dehydrogenase
NT05HA_RS05935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NT05HA_RS05945	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NT05HA_RS05955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NT05HA_RS05960	COG0343	queuine tRNA-ribosyltransferase activity
NT05HA_RS05970	COG3945	hemerythrin HHE cation binding domain
NT05HA_RS05980	COG1862	Preprotein translocase
NT05HA_RS05985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NT05HA_RS05990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NT05HA_RS06000	COG1012	belongs to the aldehyde dehydrogenase family
NT05HA_RS06000	COG1454	alcohol dehydrogenase
NT05HA_RS06005	COG0673	inositol 2-dehydrogenase activity
NT05HA_RS06015	COG2271	Major facilitator Superfamily
NT05HA_RS06025	COG3718	enzyme involved in inositol metabolism
NT05HA_RS06030	COG1737	Transcriptional regulator
NT05HA_RS06035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NT05HA_RS06040	COG3962	Belongs to the TPP enzyme family
NT05HA_RS06050	COG0673	inositol 2-dehydrogenase activity
NT05HA_RS06080	COG0151	Belongs to the GarS family
NT05HA_RS06085	COG0138	bifunctional purine biosynthesis protein purh
NT05HA_RS06095	COG2813	Specifically methylates the guanine in position
NT05HA_RS06100	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
NT05HA_RS06105	COG0456	acetyltransferase
NT05HA_RS06110	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NT05HA_RS06125	COG4795	General secretion pathway protein
NT05HA_RS06130	COG2165	general secretion pathway protein
NT05HA_RS06165	COG0848	biopolymer transport protein
NT05HA_RS06170	COG0811	peptide transport
NT05HA_RS06175	COG0824	Thioesterase
NT05HA_RS06185	COG1294	oxidase, subunit
NT05HA_RS06190	COG1271	oxidase subunit
NT05HA_RS06205	COG0632	four-way junction helicase activity
NT05HA_RS06225	COG0494	nUDIX hydrolase
NT05HA_RS06230	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NT05HA_RS06235	COG1755	Isoprenylcysteine carboxyl methyltransferase
NT05HA_RS06240	COG4106	trans-aconitate 2-methyltransferase activity
NT05HA_RS06250	COG2271	Major facilitator Superfamily
NT05HA_RS06265	COG0346	lactoylglutathione lyase activity
NT05HA_RS06270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NT05HA_RS06275	COG2056	Na+-H+ antiporter family
NT05HA_RS06290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NT05HA_RS06300	COG0142	geranyltranstransferase activity
NT05HA_RS06315	COG0697	spore germination
NT05HA_RS06320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NT05HA_RS06335	COG4166	transmembrane transport
NT05HA_RS06340	COG0601	transmembrane transport
NT05HA_RS06345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NT05HA_RS06350	COG0444	Belongs to the ABC transporter superfamily
NT05HA_RS06355	COG4608	Belongs to the ABC transporter superfamily
NT05HA_RS06360	COG0745	RESPONSE REGULATOR receiver
NT05HA_RS06365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NT05HA_RS06385	COG2259	Doxx family
NT05HA_RS06395	COG1530	ribonuclease E activity
NT05HA_RS06410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NT05HA_RS06415	COG0626	cystathionine gamma-synthase activity
NT05HA_RS06435	COG0527	aspartate kinase activity
NT05HA_RS06450	COG5295	Hep Hag repeat protein
NT05HA_RS06460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NT05HA_RS06470	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NT05HA_RS06475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NT05HA_RS06480	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NT05HA_RS06485	COG0475	glutathione-regulated potassium exporter activity
NT05HA_RS06485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NT05HA_RS06490	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NT05HA_RS06520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NT05HA_RS06530	COG2867	negative regulation of translational initiation
NT05HA_RS06540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NT05HA_RS06550	COG1758	RNA polymerase activity
NT05HA_RS06555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NT05HA_RS06565	COG3161	chorismate lyase activity
NT05HA_RS06570	COG2850	peptidyl-arginine hydroxylation
NT05HA_RS06585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NT05HA_RS06590	COG1137	ATPase activity
NT05HA_RS06595	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NT05HA_RS06600	COG3117	lipopolysaccharide transmembrane transporter activity
NT05HA_RS06605	COG1127	ABC transporter
NT05HA_RS06610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NT05HA_RS06615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NT05HA_RS06620	COG2854	intermembrane phospholipid transfer
NT05HA_RS06625	COG3113	response to antibiotic
NT05HA_RS06630	COG5007	Belongs to the BolA IbaG family
NT05HA_RS06640	COG3028	Belongs to the UPF0307 family
NT05HA_RS06645	COG0312	modulator of DNA gyrase
NT05HA_RS06650	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NT05HA_RS06655	COG1929	Belongs to the glycerate kinase type-1 family
NT05HA_RS06660	COG2610	gluconate transmembrane transporter activity
NT05HA_RS06665	COG3835	regulator
NT05HA_RS06695	COG0513	Belongs to the DEAD box helicase family
NT05HA_RS06700	COG4785	May be involved in cell division
NT05HA_RS06710	COG2731	YhcH YjgK YiaL family protein
NT05HA_RS06715	COG3023	N-Acetylmuramoyl-L-alanine amidase
NT05HA_RS06720	COG4969	Belongs to the N-Me-Phe pilin family
NT05HA_RS06725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NT05HA_RS06730	COG1459	type II secretion system
NT05HA_RS06735	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NT05HA_RS06740	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NT05HA_RS06740	COG0237	dephospho-CoA kinase activity
NT05HA_RS06755	COG1115	amino acid carrier protein
NT05HA_RS06815	COG4145	pantothenate transmembrane transporter activity
NT05HA_RS06820	COG3924	membrane
NT05HA_RS06825	COG4783	chaperone-mediated protein folding
NT05HA_RS06830	COG0084	hydrolase, TatD family'
NT05HA_RS06835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NT05HA_RS06865	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NT05HA_RS06865	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NT05HA_RS06870	COG0772	Belongs to the SEDS family
NT05HA_RS06875	COG0768	penicillin binding
NT05HA_RS06885	COG0799	negative regulation of ribosome biogenesis
NT05HA_RS06890	COG0513	Belongs to the DEAD box helicase family
NT05HA_RS06895	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NT05HA_RS06900	COG2814	Major facilitator Superfamily
NT05HA_RS06910	COG1028	Short-chain dehydrogenase reductase Sdr
NT05HA_RS06915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NT05HA_RS06925	COG0416	fatty acid biosynthetic process
NT05HA_RS06935	COG1399	metal-binding, possibly nucleic acid-binding protein
NT05HA_RS06945	COG2226	methyltransferase
NT05HA_RS06950	COG2830	Protein of unknown function (DUF452)
NT05HA_RS06960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NT05HA_RS06965	COG0500	methyltransferase
NT05HA_RS06975	COG2453	phosphatase
NT05HA_RS06975	COG0671	phosphoesterase, PA-phosphatase related
NT05HA_RS06980	COG2267	carboxylic ester hydrolase activity
NT05HA_RS06985	COG0688	phosphatidylethanolamine metabolic process
NT05HA_RS06990	COG0545	Peptidyl-prolyl cis-trans isomerase
NT05HA_RS07000	COG2966	Psort location CytoplasmicMembrane, score
NT05HA_RS07005	COG3610	response to peptide
NT05HA_RS07010	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NT05HA_RS07015	COG1253	flavin adenine dinucleotide binding
NT05HA_RS07025	COG0084	hydrolase, TatD family'
NT05HA_RS07030	COG0470	DNA polymerase III
NT05HA_RS07035	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NT05HA_RS07045	COG0628	permease
NT05HA_RS07050	COG0347	Belongs to the P(II) protein family
NT05HA_RS07055	COG0561	phosphatase activity
NT05HA_RS07090	COG0521	Mo-molybdopterin cofactor biosynthetic process
NT05HA_RS07095	COG4589	Belongs to the CDS family
NT05HA_RS07105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NT05HA_RS07110	COG0471	metal ion transport
NT05HA_RS07110	COG0490	domain, Protein
NT05HA_RS07130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NT05HA_RS07140	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
NT05HA_RS07155	COG0575	Belongs to the CDS family
NT05HA_RS07170	COG0233	cytoplasmic translational termination
NT05HA_RS07185	COG4178	(ABC) transporter
NT05HA_RS07200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NT05HA_RS07205	COG0066	3-isopropylmalate dehydratase activity
NT05HA_RS07210	COG2226	methyltransferase
NT05HA_RS07215	COG0814	amino acid
NT05HA_RS07225	COG4783	chaperone-mediated protein folding
NT05HA_RS07235	COG0848	biopolymer transport protein
NT05HA_RS07240	COG0811	peptide transport
NT05HA_RS07245	COG4536	flavin adenine dinucleotide binding
NT05HA_RS07250	COG4137	Cytochrome C assembly protein
NT05HA_RS07255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NT05HA_RS07295	COG0758	DNA mediated transformation
NT05HA_RS07300	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NT05HA_RS07320	COG2183	response to ionizing radiation
NT05HA_RS07325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NT05HA_RS07335	COG1595	DNA-templated transcription, initiation
NT05HA_RS07345	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NT05HA_RS07350	COG3071	HemY protein
NT05HA_RS07355	COG2959	enzyme of heme biosynthesis
NT05HA_RS07365	COG0181	hydroxymethylbilane synthase activity
NT05HA_RS07375	COG2197	response regulator
NT05HA_RS07380	COG0729	surface antigen
NT05HA_RS07385	COG2911	Protein conserved in bacteria
NT05HA_RS07390	COG0248	Ppx GppA phosphatase
NT05HA_RS07410	COG2991	Protein conserved in bacteria
NT05HA_RS07415	COG1477	protein flavinylation
NT05HA_RS07420	COG2871	sodium ion transport
NT05HA_RS07425	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NT05HA_RS07430	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NT05HA_RS07435	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NT05HA_RS07450	COG0271	Belongs to the BolA IbaG family
NT05HA_RS07455	COG3056	Lipoprotein
NT05HA_RS07485	COG1194	a g-specific adenine glycosylase
NT05HA_RS07500	COG3171	Protein conserved in bacteria
NT05HA_RS07510	COG1917	Cupin 2, conserved barrel domain protein
NT05HA_RS07510	COG4977	sequence-specific DNA binding
NT05HA_RS07515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NT05HA_RS07520	COG0859	PFAM glycosyl transferase family 9
NT05HA_RS07540	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NT05HA_RS07545	COG1840	ABC-type Fe3 transport system, periplasmic component
NT05HA_RS07560	COG1178	ABC-type Fe3 transport system permease component
NT05HA_RS07565	COG3842	ATPase activity
NT05HA_RS07575	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NT05HA_RS07585	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NT05HA_RS07590	COG1561	YicC-like family, N-terminal region
NT05HA_RS07595	COG0354	folic acid binding
NT05HA_RS07615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NT05HA_RS07620	COG1381	Involved in DNA repair and RecF pathway recombination
NT05HA_RS07625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NT05HA_RS07630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NT05HA_RS07635	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NT05HA_RS07650	COG2177	Part of the ABC transporter FtsEX involved in
NT05HA_RS07655	COG2884	Cell division ATP-binding protein ftsE
NT05HA_RS07660	COG0552	protein localization to endoplasmic reticulum
NT05HA_RS07665	COG0742	ribosomal rna small subunit methyltransferase
NT05HA_RS07670	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NT05HA_RS07670	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NT05HA_RS07675	COG3715	PTS system
NT05HA_RS07680	COG3716	PTS system mannose fructose sorbose family IID component
NT05HA_RS07685	COG0561	phosphatase activity
NT05HA_RS07695	COG2271	Major facilitator Superfamily
NT05HA_RS07700	COG1120	ATPase activity
NT05HA_RS07705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT05HA_RS07710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NT05HA_RS07730	COG1215	transferase activity, transferring glycosyl groups
NT05HA_RS07735	COG1649	PFAM Uncharacterised BCR, COG1649
NT05HA_RS07735	COG0726	polysaccharide deacetylase
NT05HA_RS07750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NT05HA_RS07755	COG2364	Membrane
NT05HA_RS07760	COG0859	PFAM glycosyl transferase family 9
NT05HA_RS07765	COG1027	Aspartate ammonia-lyase
NT05HA_RS07770	COG3030	protein affecting phage T7 exclusion by the F plasmid
NT05HA_RS07775	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NT05HA_RS07780	COG0459	protein refolding
NT05HA_RS07800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NT05HA_RS07805	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NT05HA_RS07815	COG1011	Hydrolase
NT05HA_RS07840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NT05HA_RS07900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NT05HA_RS07910	COG1028	Short-chain dehydrogenase reductase Sdr
NT05HA_RS07915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NT05HA_RS07920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NT05HA_RS07925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NT05HA_RS07930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NT05HA_RS07935	COG3719	Belongs to the RNase T2 family
NT05HA_RS07945	COG0191	fructose-bisphosphate aldolase activity
NT05HA_RS07950	COG3307	-O-antigen
NT05HA_RS07955	COG2267	carboxylic ester hydrolase activity
NT05HA_RS07960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NT05HA_RS07965	COG0561	phosphatase activity
NT05HA_RS07975	COG0028	Belongs to the TPP enzyme family
NT05HA_RS07990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NT05HA_RS08000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NT05HA_RS08015	COG1131	(ABC) transporter
NT05HA_RS08020	COG0842	Transport permease protein
NT05HA_RS08080	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
NT05HA_RS08085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NT05HA_RS08095	COG2960	long-chain fatty acid transporting porin activity
NT05HA_RS08100	COG3172	ATPase kinase involved in NAD metabolism
NT05HA_RS08105	COG2129	metallophosphoesterase
NT05HA_RS08110	COG0814	amino acid
NT05HA_RS08115	COG1555	photosystem II stabilization
NT05HA_RS08135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NT05HA_RS08140	COG0561	phosphatase activity
NT05HA_RS08145	COG1040	competence protein
NT05HA_RS08165	COG0107	imidazoleglycerol-phosphate synthase activity
NT05HA_RS08180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NT05HA_RS08190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NT05HA_RS08190	COG0131	Imidazoleglycerol-phosphate dehydratase
NT05HA_RS08195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NT05HA_RS08200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NT05HA_RS08205	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NT05HA_RS08210	COG1114	Component of the transport system for branched-chain amino acids
NT05HA_RS08245	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NT05HA_RS08255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NT05HA_RS08270	COG0589	response to stress
NT05HA_RS08275	COG3956	TIGRFAM MazG family protein
NT05HA_RS08280	COG0402	S-adenosylhomocysteine deaminase activity
NT05HA_RS08285	COG3083	sulfuric ester hydrolase activity
NT05HA_RS08300	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NT05HA_RS08305	COG0745	RESPONSE REGULATOR receiver
NT05HA_RS08310	COG2205	protein histidine kinase activity
NT05HA_RS08315	COG0786	glutamate:sodium symporter activity
NT05HA_RS08330	COG3012	SEC-C Motif Domain Protein
NT05HA_RS08335	COG2258	MOSC domain
NT05HA_RS08340	COG0433	COG0433 Predicted ATPase
NT05HA_RS08350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NT05HA_RS08355	COG1349	DNA-binding transcription factor activity
NT05HA_RS08365	COG3068	Protein conserved in bacteria
NT05HA_RS08370	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NT05HA_RS08395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NT05HA_RS08415	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NT05HA_RS08430	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
NT05HA_RS08505	COG0582	viral genome integration into host DNA
NT05HA_RS08515	COG3177	Filamentation induced by cAMP protein fic
NT05HA_RS08535	COG0513	Belongs to the DEAD box helicase family
NT05HA_RS08545	COG3201	nicotinamide mononucleotide transporter
NT05HA_RS08555	COG0564	pseudouridine synthase activity
NT05HA_RS08625	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NT05HA_RS08650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NT05HA_RS08650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NT05HA_RS08650	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NT05HA_RS08655	COG1105	Belongs to the carbohydrate kinase PfkB family
NT05HA_RS08660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NT05HA_RS08660	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NT05HA_RS08670	COG0746	molybdenum cofactor guanylyltransferase activity
NT05HA_RS08675	COG3084	Protein conserved in bacteria
NT05HA_RS08680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NT05HA_RS08685	COG3085	chromosome segregation
NT05HA_RS08780	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NT05HA_RS08790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NT05HA_RS08810	COG0754	glutathionylspermidine amidase activity
NT05HA_RS08820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NT05HA_RS08820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NT05HA_RS08830	COG5645	(Lipo)protein
NT05HA_RS08835	COG0210	DNA helicase
NT05HA_RS08860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NT05HA_RS08865	COG0110	maltose O-acetyltransferase activity
NT05HA_RS08870	COG1238	metal cluster binding
NT05HA_RS08880	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NT05HA_RS08905	COG1349	DNA-binding transcription factor activity
NT05HA_RS08910	COG0606	chelatase, subunit chli
NT05HA_RS08945	COG2861	carbohydrate metabolic process
NT05HA_RS08950	COG4942	peptidase
NT05HA_RS08955	COG2354	Protein conserved in bacteria
NT05HA_RS08985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NT05HA_RS09010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NT05HA_RS09015	COG0488	(ABC) transporter
NT05HA_RS09020	COG2095	MarC family integral membrane protein
NT05HA_RS09045	COG0546	phosphoglycolate phosphatase activity
NT05HA_RS09050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NT05HA_RS09070	COG0585	pseudouridine synthase activity
NT05HA_RS09080	COG1238	metal cluster binding
NT05HA_RS09090	COG1388	LysM domain
NT05HA_RS09090	COG4942	peptidase
NT05HA_RS09110	COG2814	Major facilitator Superfamily
NT05HA_RS09115	COG1763	Mo-molybdopterin cofactor biosynthetic process
NT05HA_RS09120	COG3086	response to oxidative stress
NT05HA_RS09125	COG3026	antisigma factor binding
NT05HA_RS09130	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
NT05HA_RS09135	COG1595	DNA-templated transcription, initiation
NT05HA_RS09150	COG0442	prolyl-tRNA aminoacylation
NT05HA_RS09155	COG1921	L-seryl-tRNASec selenium transferase activity
NT05HA_RS09160	COG3276	selenocysteine insertion sequence binding
NT05HA_RS09170	COG1902	pentaerythritol trinitrate reductase activity
NT05HA_RS09175	COG1285	pathogenesis
NT05HA_RS09185	COG0733	neurotransmitter:sodium symporter activity
NT05HA_RS09200	COG1132	(ABC) transporter
NT05HA_RS09205	COG4988	ABC transporter
NT05HA_RS09210	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NT05HA_RS09215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NT05HA_RS09230	COG1045	serine acetyltransferase
NT05HA_RS09240	COG1494	fructose-1,6-bisphosphatase
NT05HA_RS09245	COG3074	FtsZ-dependent cytokinesis
NT05HA_RS09250	COG0716	FMN binding
NT05HA_RS09260	COG0357	Ribosomal RNA small subunit methyltransferase G
NT05HA_RS09265	COG3312	ion transport
NT05HA_RS09280	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NT05HA_RS09285	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NT05HA_RS09295	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NT05HA_RS09300	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NT05HA_RS09315	COG0859	PFAM glycosyl transferase family 9
NT05HA_RS09330	COG0737	Belongs to the 5'-nucleotidase family
NT05HA_RS09335	COG1309	transcriptional regulator
NT05HA_RS09340	COG0583	DNA-binding transcription factor activity
NT05HA_RS09345	COG0678	peroxiredoxin activity
NT05HA_RS09345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NT05HA_RS09350	COG0754	glutathionylspermidine amidase activity
NT05HA_RS09355	COG3005	denitrification pathway
NT05HA_RS09360	COG3043	anaerobic respiration
NT05HA_RS09365	COG0348	domain, Protein
NT05HA_RS09370	COG0437	4 iron, 4 sulfur cluster binding
NT05HA_RS09375	COG0243	molybdopterin cofactor binding
NT05HA_RS09380	COG3062	negative regulation of establishment of protein localization
NT05HA_RS09385	COG3850	Histidine kinase
NT05HA_RS09400	COG1275	C4-dicarboxylate transporter malic acid transport protein
NT05HA_RS09405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NT05HA_RS09410	COG2195	Cleaves the N-terminal amino acid of tripeptides
NT05HA_RS09425	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NT05HA_RS09430	COG2818	Glycosylase
NT05HA_RS09435	COG3477	response to acidic pH
NT05HA_RS09440	COG0019	diaminopimelate decarboxylase activity
NT05HA_RS09450	COG0514	ATP-dependent DNA helicase (RecQ)
NT05HA_RS09455	COG0187	DNA topoisomerase II activity
NT05HA_RS09460	COG1072	(Pantothenic acid kinase))
NT05HA_RS09490	COG1126	abc transporter atp-binding protein
NT05HA_RS09495	COG0765	amino acid transport
NT05HA_RS09500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NT05HA_RS09505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NT05HA_RS09515	COG0545	Peptidyl-prolyl cis-trans isomerase
NT05HA_RS09520	COG2964	Protein conserved in bacteria
NT05HA_RS09525	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NT05HA_RS09535	COG2168	tRNA wobble position uridine thiolation
NT05HA_RS09545	COG0840	transmembrane signaling receptor activity
NT05HA_RS09550	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NT05HA_RS09575	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NT05HA_RS09590	COG0702	epimerase
NT05HA_RS09595	COG1733	regulation of RNA biosynthetic process
NT05HA_RS09600	COG0752	glycyl-tRNA synthetase alpha subunit
NT05HA_RS09620	COG0751	glycine-tRNA ligase activity
NT05HA_RS09630	COG0805	protein transport
NT05HA_RS09650	COG3165	ubiquinone biosynthetic process from chorismate
NT05HA_RS09660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NT05HA_RS09665	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NT05HA_RS09670	COG1011	Hydrolase
NT05HA_RS09675	COG0494	nUDIX hydrolase
NT05HA_RS09680	COG1917	Cupin 2, conserved barrel domain protein
NT05HA_RS09680	COG4977	sequence-specific DNA binding
NT05HA_RS09685	COG3059	membrane
NT05HA_RS09690	COG1297	OPT oligopeptide transporter protein
NT05HA_RS09700	COG1218	3'(2'),5'-bisphosphate nucleotidase
NT05HA_RS09705	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NT05HA_RS09710	COG0363	glucosamine-6-phosphate deaminase activity
NT05HA_RS09775	COG0747	negative chemotaxis
NT05HA_RS09780	COG2853	Lipoprotein
NT05HA_RS09795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NT05HA_RS09855	COG3501	Rhs element vgr protein
NT05HA_RS09875	COG2990	Protein conserved in bacteria
NT05HA_RS09880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NT05HA_RS09900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NT05HA_RS09905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NT05HA_RS09950	COG0569	domain protein
NT05HA_RS09955	COG1970	mechanosensitive ion channel activity
NT05HA_RS09960	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NT05HA_RS09975	COG2841	Protein conserved in bacteria
NT05HA_RS09980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NT05HA_RS09985	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
NT05HA_RS09990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NT05HA_RS09995	COG3036	rescue of stalled ribosome
NT05HA_RS10005	COG1393	Belongs to the ArsC family
NT05HA_RS10015	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NT05HA_RS10020	COG1522	sequence-specific DNA binding
NT05HA_RS10030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NT05HA_RS10035	COG0038	chloride channel
NT05HA_RS10045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NT05HA_RS10050	COG0549	Belongs to the carbamate kinase family
NT05HA_RS10055	COG1288	antiporter activity
NT05HA_RS10060	COG1522	sequence-specific DNA binding
NT05HA_RS10065	COG0051	transcription antitermination factor activity, RNA binding
NT05HA_RS10070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NT05HA_RS10075	COG0088	Forms part of the polypeptide exit tunnel
NT05HA_RS10080	COG0089	rRNA binding
NT05HA_RS10085	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NT05HA_RS10090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NT05HA_RS10095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NT05HA_RS10100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NT05HA_RS10105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NT05HA_RS10115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NT05HA_RS10130	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NT05HA_RS10150	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NT05HA_RS10170	COG0201	protein transport
NT05HA_RS10185	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NT05HA_RS10200	COG0463	Glycosyl transferase, family 2
NT05HA_RS10205	COG1519	Transferase
NT05HA_RS10210	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NT05HA_RS10220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NT05HA_RS10225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NT05HA_RS10230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NT05HA_RS10250	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
NT05HA_RS10255	COG1466	dna polymerase III delta subunit
NT05HA_RS10265	COG0494	nUDIX hydrolase
NT05HA_RS10280	COG4701	Protein of unknown function (DUF721)
NT05HA_RS10285	COG0789	Transcriptional regulator
NT05HA_RS10290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NT05HA_RS10315	COG0583	DNA-binding transcription factor activity
NT05HA_RS10350	COG3384	dioxygenase
NT05HA_RS10355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NT05HA_RS10360	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NT05HA_RS10365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NT05HA_RS10375	COG4796	Type ii and iii secretion system protein
NT05HA_RS10395	COG4972	Pilus assembly protein
NT05HA_RS10405	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NT05HA_RS10410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NT05HA_RS10435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NT05HA_RS10470	COG3306	glycosyltransferase involved in LPS biosynthesis
NT05HA_RS10480	COG3306	glycosyltransferase involved in LPS biosynthesis
NT05HA_RS10490	COG4750	Nucleotidyl transferase
NT05HA_RS10505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NT05HA_RS10510	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NT05HA_RS10515	COG1309	transcriptional regulator
NT05HA_RS10520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NT05HA_RS10525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NT05HA_RS10530	COG0500	methyltransferase
NT05HA_RS10540	COG0762	integral membrane protein
NT05HA_RS10550	COG0778	Nitroreductase
NT05HA_RS10555	COG1368	sulfuric ester hydrolase activity
NT05HA_RS10565	COG1496	oxidoreductase activity
NT05HA_RS10580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NT05HA_RS10595	COG0006	proline dipeptidase activity
NT05HA_RS10605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NT05HA_RS10625	COG0335	large ribosomal subunit rRNA binding
NT05HA_RS10635	COG1792	Involved in formation and maintenance of cell shape
NT05HA_RS10640	COG1077	Cell shape determining protein MreB Mrl
NT05HA_RS10645	COG0557	exoribonuclease II activity
NT05HA_RS10655	COG2271	Major facilitator Superfamily
NT05HA_RS10660	COG0584	glycerophosphoryl diester phosphodiesterase
NT05HA_RS10675	COG0583	DNA-binding transcription factor activity
NT05HA_RS10680	COG2962	Rard protein
NT05HA_RS10695	COG0551	DNA topoisomerase type I activity
NT05HA_RS10715	COG0705	Rhomboid family
NT05HA_RS10720	COG1349	DNA-binding transcription factor activity
NT05HA_RS10725	COG4206	TonB-dependent receptor
NT05HA_RS10725	COG1629	transport
NT05HA_RS10785	COG5566	PFAM Mor transcription activator
NT05HA_RS10790	COG0582	viral genome integration into host DNA
NT05HA_RS10800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NT05HA_RS10810	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NT05HA_RS10815	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NT05HA_RS10835	COG3115	cell septum assembly
NT05HA_RS10845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NT05HA_RS10850	COG1573	uracil-dna glycosylase
NT05HA_RS10855	COG0012	GTP binding
NT05HA_RS10860	COG0193	aminoacyl-tRNA hydrolase activity
NT05HA_RS10870	COG0560	Phosphoserine phosphatase
NT05HA_RS10895	COG0728	peptidoglycan biosynthetic process
NT05HA_RS10900	COG0196	riboflavin kinase activity
NT05HA_RS10920	COG1555	photosystem II stabilization
NT05HA_RS10925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NT05HA_RS10935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NT05HA_RS10940	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NT05HA_RS10945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NT05HA_RS10950	COG2321	neutral zinc metallopeptidase
NT05HA_RS10955	COG1652	LysM domain
NT05HA_RS10965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NT05HA_RS10970	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NT05HA_RS10975	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NT05HA_RS10990	COG0436	Aminotransferase
NT05HA_RS11000	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NT05HA_RS11005	COG2267	carboxylic ester hydrolase activity
NT05HA_RS11015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NT05HA_RS11020	COG3091	SprT-like family
NT05HA_RS11025	COG0814	amino acid
NT05HA_RS11070	COG3501	Rhs element vgr protein
NT05HA_RS11095	COG0028	Belongs to the TPP enzyme family
NT05HA_RS11100	COG0028	Belongs to the TPP enzyme family
NT05HA_RS11105	COG0028	Belongs to the TPP enzyme family