locus-tag	class	description
ADJ80_RS00010	COG2731	YhcH YjgK YiaL family protein
ADJ80_RS00015	COG3023	N-Acetylmuramoyl-L-alanine amidase
ADJ80_RS00020	COG4969	Belongs to the N-Me-Phe pilin family
ADJ80_RS00025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ADJ80_RS00030	COG1459	type II secretion system
ADJ80_RS00040	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ADJ80_RS00040	COG0237	dephospho-CoA kinase activity
ADJ80_RS00055	COG1115	amino acid carrier protein
ADJ80_RS00060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ADJ80_RS00075	COG0737	Belongs to the 5'-nucleotidase family
ADJ80_RS00120	COG4145	pantothenate transmembrane transporter activity
ADJ80_RS00125	COG3924	membrane
ADJ80_RS00130	COG4783	chaperone-mediated protein folding
ADJ80_RS00135	COG0084	hydrolase, TatD family'
ADJ80_RS00140	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADJ80_RS00165	COG1686	Belongs to the peptidase S11 family
ADJ80_RS00170	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ADJ80_RS00170	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ADJ80_RS00175	COG0772	Belongs to the SEDS family
ADJ80_RS00180	COG0768	penicillin binding
ADJ80_RS00190	COG0799	negative regulation of ribosome biogenesis
ADJ80_RS00195	COG0513	Belongs to the DEAD box helicase family
ADJ80_RS00200	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ADJ80_RS00205	COG2814	Major facilitator Superfamily
ADJ80_RS00215	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ80_RS00220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ADJ80_RS00240	COG1399	metal-binding, possibly nucleic acid-binding protein
ADJ80_RS00245	COG0500	methyltransferase
ADJ80_RS00255	COG0671	phosphoesterase, PA-phosphatase related
ADJ80_RS00255	COG2453	phosphatase
ADJ80_RS00260	COG2267	carboxylic ester hydrolase activity
ADJ80_RS00265	COG0688	phosphatidylethanolamine metabolic process
ADJ80_RS00270	COG0545	Peptidyl-prolyl cis-trans isomerase
ADJ80_RS00280	COG2966	Psort location CytoplasmicMembrane, score
ADJ80_RS00285	COG3610	response to peptide
ADJ80_RS00290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ADJ80_RS00295	COG1253	flavin adenine dinucleotide binding
ADJ80_RS00305	COG0084	hydrolase, TatD family'
ADJ80_RS00310	COG0470	DNA polymerase III
ADJ80_RS00315	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADJ80_RS00320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ADJ80_RS00325	COG0628	permease
ADJ80_RS00330	COG0347	Belongs to the P(II) protein family
ADJ80_RS00335	COG0561	phosphatase activity
ADJ80_RS00400	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADJ80_RS00405	COG4589	Belongs to the CDS family
ADJ80_RS00415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADJ80_RS00420	COG0471	metal ion transport
ADJ80_RS00420	COG0490	domain, Protein
ADJ80_RS00440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ADJ80_RS00450	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ADJ80_RS00465	COG0575	Belongs to the CDS family
ADJ80_RS00480	COG0233	cytoplasmic translational termination
ADJ80_RS00500	COG4178	(ABC) transporter
ADJ80_RS00515	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADJ80_RS00520	COG0066	3-isopropylmalate dehydratase activity
ADJ80_RS00525	COG2226	methyltransferase
ADJ80_RS00530	COG0814	amino acid
ADJ80_RS00540	COG4783	chaperone-mediated protein folding
ADJ80_RS00545	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ADJ80_RS00550	COG0848	biopolymer transport protein
ADJ80_RS00555	COG0811	peptide transport
ADJ80_RS00560	COG4536	flavin adenine dinucleotide binding
ADJ80_RS00565	COG4137	Cytochrome C assembly protein
ADJ80_RS00570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ADJ80_RS00610	COG0758	DNA mediated transformation
ADJ80_RS00615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADJ80_RS00620	COG1126	abc transporter atp-binding protein
ADJ80_RS00630	COG0765	amino acid transport
ADJ80_RS00635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ADJ80_RS00655	COG2183	response to ionizing radiation
ADJ80_RS00660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADJ80_RS00670	COG1595	DNA-templated transcription, initiation
ADJ80_RS00680	COG4771	TonB-dependent receptor
ADJ80_RS00685	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ADJ80_RS00690	COG3071	HemY protein
ADJ80_RS00695	COG2959	enzyme of heme biosynthesis
ADJ80_RS00705	COG0181	hydroxymethylbilane synthase activity
ADJ80_RS00715	COG2197	response regulator
ADJ80_RS00720	COG0729	surface antigen
ADJ80_RS00725	COG2911	Protein conserved in bacteria
ADJ80_RS00730	COG0248	Ppx GppA phosphatase
ADJ80_RS00750	COG0482	sulfurtransferase activity
ADJ80_RS00755	COG1942	4-Oxalocrotonate Tautomerase
ADJ80_RS00760	COG2991	Protein conserved in bacteria
ADJ80_RS00765	COG1477	protein flavinylation
ADJ80_RS00770	COG2871	sodium ion transport
ADJ80_RS00775	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ADJ80_RS00780	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ADJ80_RS00785	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ADJ80_RS00800	COG0271	Belongs to the BolA IbaG family
ADJ80_RS00805	COG3056	Lipoprotein
ADJ80_RS00835	COG1194	a g-specific adenine glycosylase
ADJ80_RS00845	COG3171	Protein conserved in bacteria
ADJ80_RS00850	COG1132	(ABC) transporter
ADJ80_RS00855	COG4977	sequence-specific DNA binding
ADJ80_RS00855	COG1917	Cupin 2, conserved barrel domain protein
ADJ80_RS00860	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADJ80_RS00865	COG0859	PFAM glycosyl transferase family 9
ADJ80_RS00870	COG3642	lipopolysaccharide core region biosynthetic process
ADJ80_RS00885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADJ80_RS00890	COG1840	ABC-type Fe3 transport system, periplasmic component
ADJ80_RS00900	COG1178	ABC-type Fe3 transport system permease component
ADJ80_RS00905	COG3842	ATPase activity
ADJ80_RS00915	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ADJ80_RS00925	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ADJ80_RS00930	COG1561	YicC-like family, N-terminal region
ADJ80_RS00935	COG0354	folic acid binding
ADJ80_RS00945	COG2249	NAD(P)H dehydrogenase (quinone) activity
ADJ80_RS00950	COG1733	regulation of RNA biosynthetic process
ADJ80_RS00955	COG2391	methyltransferase activity
ADJ80_RS00960	COG0425	Belongs to the sulfur carrier protein TusA family
ADJ80_RS00965	COG0475	glutathione-regulated potassium exporter activity
ADJ80_RS00965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ADJ80_RS00985	COG1381	Involved in DNA repair and RecF pathway recombination
ADJ80_RS00990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADJ80_RS00995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADJ80_RS01000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ADJ80_RS01010	COG0789	Transcriptional regulator
ADJ80_RS01015	COG1230	cation diffusion facilitator family transporter
ADJ80_RS01025	COG2177	Part of the ABC transporter FtsEX involved in
ADJ80_RS01030	COG2884	Cell division ATP-binding protein ftsE
ADJ80_RS01035	COG0552	protein localization to endoplasmic reticulum
ADJ80_RS01040	COG0742	ribosomal rna small subunit methyltransferase
ADJ80_RS01045	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADJ80_RS01045	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADJ80_RS01050	COG3715	PTS system
ADJ80_RS01055	COG3716	PTS system mannose fructose sorbose family IID component
ADJ80_RS01060	COG0561	phosphatase activity
ADJ80_RS01065	COG2814	Major facilitator Superfamily
ADJ80_RS01070	COG2186	Transcriptional regulator
ADJ80_RS01080	COG0673	inositol 2-dehydrogenase activity
ADJ80_RS01105	COG2271	Major facilitator Superfamily
ADJ80_RS01110	COG1120	ATPase activity
ADJ80_RS01115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADJ80_RS01120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADJ80_RS01130	COG4773	Receptor
ADJ80_RS01140	COG1215	transferase activity, transferring glycosyl groups
ADJ80_RS01145	COG1649	PFAM Uncharacterised BCR, COG1649
ADJ80_RS01145	COG0726	polysaccharide deacetylase
ADJ80_RS01160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ADJ80_RS01165	COG2364	Membrane
ADJ80_RS01170	COG0859	PFAM glycosyl transferase family 9
ADJ80_RS01175	COG1027	Aspartate ammonia-lyase
ADJ80_RS01180	COG3030	protein affecting phage T7 exclusion by the F plasmid
ADJ80_RS01185	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ADJ80_RS01190	COG0459	protein refolding
ADJ80_RS01210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADJ80_RS01220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ADJ80_RS01225	COG1011	Hydrolase
ADJ80_RS01250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADJ80_RS01310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADJ80_RS01320	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ80_RS01325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADJ80_RS01330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADJ80_RS01335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADJ80_RS01340	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADJ80_RS01345	COG3719	Belongs to the RNase T2 family
ADJ80_RS01355	COG0191	fructose-bisphosphate aldolase activity
ADJ80_RS01360	COG3307	-O-antigen
ADJ80_RS01365	COG2267	carboxylic ester hydrolase activity
ADJ80_RS01370	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADJ80_RS01375	COG0561	phosphatase activity
ADJ80_RS01385	COG0028	Belongs to the TPP enzyme family
ADJ80_RS01405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADJ80_RS01415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADJ80_RS01430	COG1131	(ABC) transporter
ADJ80_RS01435	COG0842	Transport permease protein
ADJ80_RS01490	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ADJ80_RS01495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADJ80_RS01505	COG2960	long-chain fatty acid transporting porin activity
ADJ80_RS01510	COG3172	ATPase kinase involved in NAD metabolism
ADJ80_RS01515	COG2129	metallophosphoesterase
ADJ80_RS01520	COG0814	amino acid
ADJ80_RS01525	COG1596	polysaccharide export
ADJ80_RS01525	COG1555	photosystem II stabilization
ADJ80_RS01545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ADJ80_RS01550	COG0561	phosphatase activity
ADJ80_RS01555	COG1040	competence protein
ADJ80_RS01575	COG0107	imidazoleglycerol-phosphate synthase activity
ADJ80_RS01595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADJ80_RS01610	COG0131	Imidazoleglycerol-phosphate dehydratase
ADJ80_RS01610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ADJ80_RS01615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADJ80_RS01620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ADJ80_RS01625	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ADJ80_RS01630	COG1114	Component of the transport system for branched-chain amino acids
ADJ80_RS01665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ADJ80_RS01675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ADJ80_RS01685	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ADJ80_RS01695	COG0589	response to stress
ADJ80_RS01700	COG3956	TIGRFAM MazG family protein
ADJ80_RS01705	COG0402	S-adenosylhomocysteine deaminase activity
ADJ80_RS01710	COG3083	sulfuric ester hydrolase activity
ADJ80_RS01725	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADJ80_RS01730	COG0745	RESPONSE REGULATOR receiver
ADJ80_RS01735	COG2205	protein histidine kinase activity
ADJ80_RS01740	COG0786	glutamate:sodium symporter activity
ADJ80_RS01755	COG3012	SEC-C Motif Domain Protein
ADJ80_RS01760	COG2258	MOSC domain
ADJ80_RS01765	COG0433	COG0433 Predicted ATPase
ADJ80_RS01775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADJ80_RS01780	COG1349	DNA-binding transcription factor activity
ADJ80_RS01790	COG3068	Protein conserved in bacteria
ADJ80_RS01795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ADJ80_RS01840	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADJ80_RS01875	COG0513	Belongs to the DEAD box helicase family
ADJ80_RS01885	COG3201	nicotinamide mononucleotide transporter
ADJ80_RS01895	COG0564	pseudouridine synthase activity
ADJ80_RS01965	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADJ80_RS01975	COG1119	ATPase activity
ADJ80_RS01995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADJ80_RS01995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADJ80_RS01995	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ADJ80_RS02000	COG1105	Belongs to the carbohydrate kinase PfkB family
ADJ80_RS02005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADJ80_RS02005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADJ80_RS02015	COG0746	molybdenum cofactor guanylyltransferase activity
ADJ80_RS02020	COG3084	Protein conserved in bacteria
ADJ80_RS02025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADJ80_RS02030	COG3085	chromosome segregation
ADJ80_RS02095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ADJ80_RS02105	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADJ80_RS02110	COG1114	Component of the transport system for branched-chain amino acids
ADJ80_RS02125	COG0754	glutathionylspermidine amidase activity
ADJ80_RS02135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADJ80_RS02135	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADJ80_RS02145	COG5645	(Lipo)protein
ADJ80_RS02150	COG0210	DNA helicase
ADJ80_RS02175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADJ80_RS02180	COG0110	maltose O-acetyltransferase activity
ADJ80_RS02185	COG1238	metal cluster binding
ADJ80_RS02195	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ADJ80_RS02210	COG0425	Belongs to the sulfur carrier protein TusA family
ADJ80_RS02215	COG2391	methyltransferase activity
ADJ80_RS02220	COG0697	spore germination
ADJ80_RS02235	COG1349	DNA-binding transcription factor activity
ADJ80_RS02240	COG0606	chelatase, subunit chli
ADJ80_RS02275	COG2861	carbohydrate metabolic process
ADJ80_RS02280	COG4942	peptidase
ADJ80_RS02285	COG2354	Protein conserved in bacteria
ADJ80_RS02315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADJ80_RS02340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ADJ80_RS02345	COG0488	(ABC) transporter
ADJ80_RS02350	COG2095	MarC family integral membrane protein
ADJ80_RS02360	COG0546	phosphoglycolate phosphatase activity
ADJ80_RS02365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADJ80_RS02395	COG1238	metal cluster binding
ADJ80_RS02405	COG1388	LysM domain
ADJ80_RS02405	COG4942	peptidase
ADJ80_RS02425	COG2814	Major facilitator Superfamily
ADJ80_RS02430	COG1763	Mo-molybdopterin cofactor biosynthetic process
ADJ80_RS02435	COG3086	response to oxidative stress
ADJ80_RS02440	COG3026	antisigma factor binding
ADJ80_RS02445	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ADJ80_RS02450	COG1595	DNA-templated transcription, initiation
ADJ80_RS02465	COG0442	prolyl-tRNA aminoacylation
ADJ80_RS02470	COG1921	L-seryl-tRNASec selenium transferase activity
ADJ80_RS02475	COG3276	selenocysteine insertion sequence binding
ADJ80_RS02485	COG1902	pentaerythritol trinitrate reductase activity
ADJ80_RS02490	COG1285	pathogenesis
ADJ80_RS02500	COG0733	neurotransmitter:sodium symporter activity
ADJ80_RS02510	COG1132	(ABC) transporter
ADJ80_RS02515	COG4988	ABC transporter
ADJ80_RS02520	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ADJ80_RS02525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ADJ80_RS02540	COG1045	serine acetyltransferase
ADJ80_RS02550	COG1494	fructose-1,6-bisphosphatase
ADJ80_RS02555	COG3074	FtsZ-dependent cytokinesis
ADJ80_RS02560	COG0716	FMN binding
ADJ80_RS02575	COG3312	ion transport
ADJ80_RS02590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADJ80_RS02605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ADJ80_RS02610	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ADJ80_RS02625	COG0859	PFAM glycosyl transferase family 9
ADJ80_RS02630	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ADJ80_RS02650	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ADJ80_RS02660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADJ80_RS02665	COG1309	transcriptional regulator
ADJ80_RS02670	COG0583	DNA-binding transcription factor activity
ADJ80_RS02675	COG0678	peroxiredoxin activity
ADJ80_RS02675	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ADJ80_RS02680	COG0754	glutathionylspermidine amidase activity
ADJ80_RS02685	COG3005	denitrification pathway
ADJ80_RS02690	COG3043	anaerobic respiration
ADJ80_RS02695	COG0348	domain, Protein
ADJ80_RS02700	COG0437	4 iron, 4 sulfur cluster binding
ADJ80_RS02705	COG0243	molybdopterin cofactor binding
ADJ80_RS02710	COG3062	negative regulation of establishment of protein localization
ADJ80_RS02715	COG3850	Histidine kinase
ADJ80_RS02730	COG1275	C4-dicarboxylate transporter malic acid transport protein
ADJ80_RS02735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADJ80_RS02740	COG2195	Cleaves the N-terminal amino acid of tripeptides
ADJ80_RS02755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ADJ80_RS02760	COG2818	Glycosylase
ADJ80_RS02765	COG3477	response to acidic pH
ADJ80_RS02770	COG0019	diaminopimelate decarboxylase activity
ADJ80_RS02780	COG0514	ATP-dependent DNA helicase (RecQ)
ADJ80_RS02790	COG1072	(Pantothenic acid kinase))
ADJ80_RS02820	COG1126	abc transporter atp-binding protein
ADJ80_RS02825	COG0765	amino acid transport
ADJ80_RS02830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADJ80_RS02835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADJ80_RS02840	COG0243	molybdopterin cofactor binding
ADJ80_RS02845	COG0437	4 iron, 4 sulfur cluster binding
ADJ80_RS02850	COG3302	dmso reductase anchor subunit
ADJ80_RS02855	COG3381	protein complex oligomerization
ADJ80_RS02860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADJ80_RS02860	COG2221	Nitrite and sulphite reductase 4Fe-4S
ADJ80_RS02870	COG0545	Peptidyl-prolyl cis-trans isomerase
ADJ80_RS02875	COG2964	Protein conserved in bacteria
ADJ80_RS02880	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ADJ80_RS02890	COG2168	tRNA wobble position uridine thiolation
ADJ80_RS02900	COG0840	transmembrane signaling receptor activity
ADJ80_RS02905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ADJ80_RS02935	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ADJ80_RS02940	COG0752	glycyl-tRNA synthetase alpha subunit
ADJ80_RS02950	COG4545	Glutaredoxin-related protein
ADJ80_RS02965	COG0751	glycine-tRNA ligase activity
ADJ80_RS02975	COG0805	protein transport
ADJ80_RS02995	COG3165	ubiquinone biosynthetic process from chorismate
ADJ80_RS03005	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ADJ80_RS03010	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ADJ80_RS03015	COG1011	Hydrolase
ADJ80_RS03020	COG0494	nUDIX hydrolase
ADJ80_RS03025	COG1917	Cupin 2, conserved barrel domain protein
ADJ80_RS03025	COG4977	sequence-specific DNA binding
ADJ80_RS03030	COG3059	membrane
ADJ80_RS03035	COG1297	OPT oligopeptide transporter protein
ADJ80_RS03045	COG1218	3'(2'),5'-bisphosphate nucleotidase
ADJ80_RS03050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ADJ80_RS03055	COG0363	glucosamine-6-phosphate deaminase activity
ADJ80_RS03070	COG1794	racemase activity, acting on amino acids and derivatives
ADJ80_RS03115	COG0747	negative chemotaxis
ADJ80_RS03120	COG2853	Lipoprotein
ADJ80_RS03135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADJ80_RS03190	COG3501	Rhs element vgr protein
ADJ80_RS03210	COG2990	Protein conserved in bacteria
ADJ80_RS03215	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ADJ80_RS03235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ADJ80_RS03240	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ADJ80_RS03275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADJ80_RS03275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADJ80_RS03280	COG0569	domain protein
ADJ80_RS03285	COG1970	mechanosensitive ion channel activity
ADJ80_RS03290	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ADJ80_RS03305	COG2841	Protein conserved in bacteria
ADJ80_RS03310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADJ80_RS03315	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
ADJ80_RS03320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADJ80_RS03325	COG3036	rescue of stalled ribosome
ADJ80_RS03340	COG1393	Belongs to the ArsC family
ADJ80_RS03350	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ADJ80_RS03355	COG1522	sequence-specific DNA binding
ADJ80_RS03365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADJ80_RS03370	COG0038	chloride channel
ADJ80_RS03375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADJ80_RS03380	COG0549	Belongs to the carbamate kinase family
ADJ80_RS03385	COG1288	antiporter activity
ADJ80_RS03390	COG1522	sequence-specific DNA binding
ADJ80_RS03395	COG0051	transcription antitermination factor activity, RNA binding
ADJ80_RS03400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADJ80_RS03410	COG0089	rRNA binding
ADJ80_RS03415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADJ80_RS03420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADJ80_RS03425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ADJ80_RS03430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADJ80_RS03435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADJ80_RS03445	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADJ80_RS03460	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADJ80_RS03480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ADJ80_RS03500	COG0201	protein transport
ADJ80_RS03515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ADJ80_RS03530	COG0463	Glycosyl transferase, family 2
ADJ80_RS03535	COG1519	Transferase
ADJ80_RS03545	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ADJ80_RS03550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADJ80_RS03555	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADJ80_RS03560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ADJ80_RS03580	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ADJ80_RS03585	COG1466	dna polymerase III delta subunit
ADJ80_RS03595	COG0494	nUDIX hydrolase
ADJ80_RS03610	COG4701	Protein of unknown function (DUF721)
ADJ80_RS03615	COG0789	Transcriptional regulator
ADJ80_RS03620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADJ80_RS03640	COG3384	dioxygenase
ADJ80_RS03645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ADJ80_RS03650	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ADJ80_RS03655	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ADJ80_RS03665	COG4796	Type ii and iii secretion system protein
ADJ80_RS03685	COG4972	Pilus assembly protein
ADJ80_RS03690	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ADJ80_RS03695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ADJ80_RS03700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADJ80_RS03720	COG5301	cellulose 1,4-beta-cellobiosidase activity
ADJ80_RS03830	COG4373	Mu-like prophage FluMu protein gp28
ADJ80_RS03840	COG0640	Transcriptional regulator
ADJ80_RS03860	COG3023	N-Acetylmuramoyl-L-alanine amidase
ADJ80_RS03890	COG4382	Mu-like prophage protein Gp16
ADJ80_RS03905	COG4396	Host-nuclease inhibitor protein Gam
ADJ80_RS03920	COG2842	Transposition protein
ADJ80_RS03925	COG2801	Transposase and inactivated derivatives
ADJ80_RS03930	COG3423	Transcriptional regulator
ADJ80_RS03960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADJ80_RS03995	COG3306	glycosyltransferase involved in LPS biosynthesis
ADJ80_RS04005	COG3306	glycosyltransferase involved in LPS biosynthesis
ADJ80_RS04010	COG1442	glycosyl transferase family 8
ADJ80_RS04015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADJ80_RS04020	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ADJ80_RS04025	COG1309	transcriptional regulator
ADJ80_RS04030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADJ80_RS04035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADJ80_RS04040	COG0500	methyltransferase
ADJ80_RS04050	COG0762	integral membrane protein
ADJ80_RS04060	COG0778	Nitroreductase
ADJ80_RS04065	COG1368	sulfuric ester hydrolase activity
ADJ80_RS04075	COG1496	oxidoreductase activity
ADJ80_RS04090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ADJ80_RS04105	COG0006	proline dipeptidase activity
ADJ80_RS04110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADJ80_RS04115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADJ80_RS04135	COG0335	large ribosomal subunit rRNA binding
ADJ80_RS04140	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ADJ80_RS04145	COG1792	Involved in formation and maintenance of cell shape
ADJ80_RS04150	COG1077	Cell shape determining protein MreB Mrl
ADJ80_RS04155	COG0557	exoribonuclease II activity
ADJ80_RS04165	COG2271	Major facilitator Superfamily
ADJ80_RS04175	COG0584	glycerophosphoryl diester phosphodiesterase
ADJ80_RS04185	COG0583	DNA-binding transcription factor activity
ADJ80_RS04190	COG2962	Rard protein
ADJ80_RS04205	COG0551	DNA topoisomerase type I activity
ADJ80_RS04220	COG1132	(ABC) transporter
ADJ80_RS04225	COG1132	(ABC) transporter
ADJ80_RS04230	COG1629	transport
ADJ80_RS04230	COG4774	siderophore transport
ADJ80_RS04250	COG0705	Rhomboid family
ADJ80_RS04255	COG1349	DNA-binding transcription factor activity
ADJ80_RS04260	COG4206	TonB-dependent receptor
ADJ80_RS04260	COG1629	transport
ADJ80_RS04270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADJ80_RS04280	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ADJ80_RS04285	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ADJ80_RS04305	COG3115	cell septum assembly
ADJ80_RS04315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ADJ80_RS04330	COG1573	uracil-dna glycosylase
ADJ80_RS04335	COG0012	GTP binding
ADJ80_RS04340	COG0193	aminoacyl-tRNA hydrolase activity
ADJ80_RS04350	COG0560	Phosphoserine phosphatase
ADJ80_RS04365	COG0728	peptidoglycan biosynthetic process
ADJ80_RS04370	COG0196	riboflavin kinase activity
ADJ80_RS04390	COG1555	photosystem II stabilization
ADJ80_RS04395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADJ80_RS04405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADJ80_RS04415	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ADJ80_RS04420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADJ80_RS04425	COG2321	neutral zinc metallopeptidase
ADJ80_RS04430	COG1652	LysM domain
ADJ80_RS04440	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ADJ80_RS04445	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ADJ80_RS04450	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ADJ80_RS04465	COG0436	Aminotransferase
ADJ80_RS04475	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ADJ80_RS04480	COG2267	carboxylic ester hydrolase activity
ADJ80_RS04490	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ADJ80_RS04495	COG3091	SprT-like family
ADJ80_RS04500	COG0814	amino acid
ADJ80_RS04505	COG1760	l-serine dehydratase
ADJ80_RS04550	COG0252	asparaginase activity
ADJ80_RS04560	COG3063	Type IV pilus biogenesis stability protein PilW
ADJ80_RS04565	COG1426	Protein conserved in bacteria
ADJ80_RS04580	COG2976	Protein conserved in bacteria
ADJ80_RS04590	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADJ80_RS04595	COG2233	PERMEase
ADJ80_RS04605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADJ80_RS04610	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADJ80_RS04620	COG0659	secondary active sulfate transmembrane transporter activity
ADJ80_RS04625	COG0800	Aldolase
ADJ80_RS04635	COG0281	malic enzyme
ADJ80_RS04635	COG0280	phosphate acetyltransferase
ADJ80_RS04640	COG1454	alcohol dehydrogenase
ADJ80_RS04645	COG0738	Major facilitator superfamily
ADJ80_RS04650	COG0235	Class ii aldolase
ADJ80_RS04660	COG1070	Carbohydrate kinase
ADJ80_RS04665	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
ADJ80_RS04670	COG1349	DNA-binding transcription factor activity
ADJ80_RS04680	COG2814	Major facilitator Superfamily
ADJ80_RS04685	COG4133	protoheme IX ABC transporter activity
ADJ80_RS04690	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADJ80_RS04695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADJ80_RS04700	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADJ80_RS04710	COG1138	Cytochrome C-type biogenesis protein
ADJ80_RS04715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADJ80_RS04745	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ADJ80_RS04750	COG0437	4 iron, 4 sulfur cluster binding
ADJ80_RS04755	COG3301	Polysulphide reductase, NrfD
ADJ80_RS04760	COG1138	Cytochrome C-type biogenesis protein
ADJ80_RS04765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADJ80_RS04770	COG3088	subunit of a heme lyase
ADJ80_RS04770	COG4235	cytochrome complex assembly
ADJ80_RS04775	COG2081	HI0933 family
ADJ80_RS04780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ADJ80_RS04785	COG1305	Transglutaminase-like
ADJ80_RS04795	COG2608	mercury ion transmembrane transporter activity
ADJ80_RS04805	COG2226	methyltransferase
ADJ80_RS04815	COG0592	DNA-directed DNA polymerase activity
ADJ80_RS04845	COG0602	queuosine metabolic process
ADJ80_RS04850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADJ80_RS04850	COG1328	CTP reductase activity
ADJ80_RS04860	COG1022	Amp-dependent synthetase and ligase
ADJ80_RS04865	COG0587	DNA-directed DNA polymerase activity
ADJ80_RS04870	COG0121	glutamine amidotransferase
ADJ80_RS04875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADJ80_RS04880	COG0165	Argininosuccinate lyase
ADJ80_RS04910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADJ80_RS04925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADJ80_RS04930	COG0494	nUDIX hydrolase
ADJ80_RS04935	COG0730	response to heat
ADJ80_RS04945	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ADJ80_RS04950	COG0590	tRNA wobble adenosine to inosine editing
ADJ80_RS04955	COG3078	GTPase activator activity
ADJ80_RS04965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADJ80_RS04970	COG0456	acetyltransferase
ADJ80_RS04975	COG0149	triose-phosphate isomerase activity
ADJ80_RS04980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ADJ80_RS04995	COG0511	ligase activity, forming carbon-carbon bonds
ADJ80_RS05000	COG0439	Biotin carboxylase
ADJ80_RS05005	COG3266	domain, Protein
ADJ80_RS05020	COG0681	Belongs to the peptidase S26 family
ADJ80_RS05035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ADJ80_RS05050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ADJ80_RS05060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADJ80_RS05075	COG0537	adenosine 5'-monophosphoramidase activity
ADJ80_RS05080	COG2116	formate transmembrane transporter activity
ADJ80_RS05085	COG1882	Formate acetyltransferase
ADJ80_RS05095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ADJ80_RS05100	COG0697	spore germination
ADJ80_RS05110	COG0204	Acyl-transferase
ADJ80_RS05120	COG5413	integral membrane protein
ADJ80_RS05125	COG2964	Protein conserved in bacteria
ADJ80_RS05130	COG0814	amino acid
ADJ80_RS05135	COG3033	Beta-eliminating lyase
ADJ80_RS05145	COG1509	lysine 2,3-aminomutase activity
ADJ80_RS05150	COG3266	domain, Protein
ADJ80_RS05150	COG3061	Opacity-associated protein A
ADJ80_RS05165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADJ80_RS05170	COG2814	Major facilitator Superfamily
ADJ80_RS05175	COG4974	Belongs to the 'phage' integrase family
ADJ80_RS05185	COG0330	HflC and HflK could
ADJ80_RS05190	COG0330	HflC and HflK could
ADJ80_RS05200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ADJ80_RS05215	COG0460	homoserine dehydrogenase
ADJ80_RS05215	COG0527	aspartate kinase activity
ADJ80_RS05230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADJ80_RS05235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ADJ80_RS05245	COG1217	gtp-binding protein TYPA
ADJ80_RS05250	COG0174	glutamine synthetase
ADJ80_RS05255	COG0861	Integral membrane protein TerC family
ADJ80_RS05265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADJ80_RS05270	COG2067	long-chain fatty acid transport protein
ADJ80_RS05275	COG3691	Protein conserved in bacteria
ADJ80_RS05280	COG0471	metal ion transport
ADJ80_RS05285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ADJ80_RS05290	COG1575	Belongs to the MenA family. Type 1 subfamily
ADJ80_RS05295	COG1720	tRNA m6t6A37 methyltransferase activity
ADJ80_RS05300	COG0789	Transcriptional regulator
ADJ80_RS05305	COG2608	mercury ion transmembrane transporter activity
ADJ80_RS05310	COG2217	Heavy metal translocating P-type atpase
ADJ80_RS05315	COG3739	integral membrane protein
ADJ80_RS05325	COG0740	serine-type endopeptidase activity
ADJ80_RS05330	COG2194	sulfuric ester hydrolase activity
ADJ80_RS05335	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADJ80_RS05335	COG2918	glutathione biosynthetic process
ADJ80_RS05385	COG4964	Belongs to the GSP D family
ADJ80_RS05410	COG1702	phosphate starvation-inducible protein PhoH
ADJ80_RS05415	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ADJ80_RS05420	COG1444	tRNA N-acetyltransferase activity
ADJ80_RS05425	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ADJ80_RS05445	COG1126	abc transporter atp-binding protein
ADJ80_RS05450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADJ80_RS05455	COG4215	(ABC) transporter
ADJ80_RS05460	COG4160	amino acid transport
ADJ80_RS05465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADJ80_RS05475	COG1966	Carbon starvation protein
ADJ80_RS05490	COG3116	cell division
ADJ80_RS05495	COG0768	penicillin binding
ADJ80_RS05505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ADJ80_RS05525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADJ80_RS05540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ADJ80_RS05545	COG0849	cell division
ADJ80_RS05550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADJ80_RS05565	COG0737	Belongs to the 5'-nucleotidase family
ADJ80_RS05570	COG0077	Prephenate dehydratase
ADJ80_RS05570	COG1605	Chorismate mutase
ADJ80_RS05580	COG0326	Molecular chaperone. Has ATPase activity
ADJ80_RS05585	COG1393	Belongs to the ArsC family
ADJ80_RS05600	COG1876	peptidase activity
ADJ80_RS05610	COG0494	nUDIX hydrolase
ADJ80_RS05615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ADJ80_RS05630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ADJ80_RS05630	COG0116	Belongs to the methyltransferase superfamily
ADJ80_RS05635	COG0783	Belongs to the Dps family
ADJ80_RS05640	COG1120	ATPase activity
ADJ80_RS05665	COG0826	peptidase U32
ADJ80_RS05695	COG0471	metal ion transport
ADJ80_RS05700	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ADJ80_RS05700	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
ADJ80_RS05705	COG3051	citrate lyase alpha subunit
ADJ80_RS05710	COG2301	Belongs to the HpcH HpaI aldolase family
ADJ80_RS05720	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ADJ80_RS05725	COG4535	Mg2 and Co2 transporter CorC
ADJ80_RS05745	COG0105	UTP biosynthetic process
ADJ80_RS05750	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADJ80_RS05775	COG0438	transferase activity, transferring glycosyl groups
ADJ80_RS05795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ADJ80_RS05805	COG1011	Hydrolase
ADJ80_RS05810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADJ80_RS05820	COG1596	polysaccharide export
ADJ80_RS05835	COG3501	Rhs element vgr protein
ADJ80_RS05845	COG3501	Rhs element vgr protein
ADJ80_RS05855	COG3209	COG3209 Rhs family protein
ADJ80_RS05880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADJ80_RS05885	COG1530	ribonuclease E activity
ADJ80_RS05890	COG2999	glutathione oxidoreductase activity
ADJ80_RS05905	COG0725	ABC transporter, periplasmic molybdate-binding protein
ADJ80_RS05910	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ADJ80_RS05915	COG3842	ATPase activity
ADJ80_RS05920	COG0157	Belongs to the NadC ModD family
ADJ80_RS05940	COG4953	penicillin-binding protein 1C
ADJ80_RS05990	COG3501	Rhs element vgr protein
ADJ80_RS06030	COG1823	symporter activity
ADJ80_RS06040	COG0795	lipopolysaccharide-transporting ATPase activity
ADJ80_RS06045	COG0795	lipopolysaccharide-transporting ATPase activity
ADJ80_RS06050	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ADJ80_RS06055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ADJ80_RS06065	COG0739	heme binding
ADJ80_RS06095	COG1648	precorrin-2 dehydrogenase activity
ADJ80_RS06095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADJ80_RS06100	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ADJ80_RS06110	COG4208	sulfate ABC transporter
ADJ80_RS06115	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADJ80_RS06120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADJ80_RS06130	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ADJ80_RS06135	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ADJ80_RS06140	COG0617	tRNA 3'-terminal CCA addition
ADJ80_RS06145	COG4991	sh3 domain protein
ADJ80_RS06150	COG0306	phosphate transporter
ADJ80_RS06155	COG1392	Phosphate transport regulator
ADJ80_RS06160	COG3025	triphosphatase activity
ADJ80_RS06165	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ADJ80_RS06170	COG1522	sequence-specific DNA binding
ADJ80_RS06185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ADJ80_RS06190	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ADJ80_RS06245	COG1518	maintenance of DNA repeat elements
ADJ80_RS06255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADJ80_RS06255	COG2190	(PTS) system
ADJ80_RS06255	COG1263	PTS System
ADJ80_RS06265	COG0058	SHG alpha-glucan phosphorylase activity
ADJ80_RS06270	COG2188	Transcriptional regulator
ADJ80_RS06280	COG0583	DNA-binding transcription factor activity
ADJ80_RS06285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ADJ80_RS06290	COG1687	branched-chain amino acid
ADJ80_RS06295	COG2990	Protein conserved in bacteria
ADJ80_RS06300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ADJ80_RS06305	COG0539	negative regulation of cytoplasmic translation
ADJ80_RS06310	COG0776	regulation of translation
ADJ80_RS06315	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ADJ80_RS06320	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ADJ80_RS06330	COG0023	Translation Initiation Factor
ADJ80_RS06335	COG3094	Invasion gene expression up-regulator, SirB
ADJ80_RS06340	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADJ80_RS06350	COG0735	belongs to the Fur family
ADJ80_RS06355	COG0716	FMN binding
ADJ80_RS06365	COG0596	Alpha beta hydrolase
ADJ80_RS06370	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ADJ80_RS06375	COG0318	PFAM AMP-dependent synthetase and ligase
ADJ80_RS06380	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ADJ80_RS06380	COG3264	Mechanosensitive ion channel
ADJ80_RS06390	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ADJ80_RS06395	COG0730	response to heat
ADJ80_RS06400	COG1560	Kdo2-lipid A biosynthetic process
ADJ80_RS06410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADJ80_RS06415	COG3021	interspecies interaction between organisms
ADJ80_RS06420	COG0251	oxidation-reduction process
ADJ80_RS06430	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ADJ80_RS06440	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ADJ80_RS06445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ADJ80_RS06450	COG0602	queuosine metabolic process
ADJ80_RS06455	COG0720	synthase
ADJ80_RS06465	COG2378	regulation of single-species biofilm formation
ADJ80_RS06485	COG1289	transmembrane transporter activity
ADJ80_RS06510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ADJ80_RS06515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ADJ80_RS06520	COG1121	(ABC) transporter
ADJ80_RS06530	COG2920	part of a sulfur-relay system
ADJ80_RS06540	COG3105	Protein conserved in bacteria
ADJ80_RS06550	COG1944	ATP diphosphatase activity
ADJ80_RS06560	COG3422	double-strand break repair
ADJ80_RS06565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADJ80_RS06565	COG1263	PTS System
ADJ80_RS06565	COG2190	(PTS) system
ADJ80_RS06570	COG2226	methyltransferase
ADJ80_RS06585	COG1846	Transcriptional regulator
ADJ80_RS06585	COG1940	carbohydrate kinase activity
ADJ80_RS06610	COG0405	Gamma-glutamyltransferase
ADJ80_RS06625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADJ80_RS06640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ADJ80_RS06650	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ADJ80_RS06655	COG1177	transmembrane transport
ADJ80_RS06660	COG1176	ABC-type spermidine putrescine transport system, permease component I
ADJ80_RS06665	COG3842	ATPase activity
ADJ80_RS06675	COG3008	intermembrane lipid transfer
ADJ80_RS06680	COG2995	paraquat-inducible protein a
ADJ80_RS06690	COG0793	Belongs to the peptidase S41A family
ADJ80_RS06695	COG2989	Protein conserved in bacteria
ADJ80_RS06700	COG3108	Peptidase M15
ADJ80_RS06705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADJ80_RS06710	COG0567	Dehydrogenase, E1 component
ADJ80_RS06715	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADJ80_RS06725	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ADJ80_RS06750	COG3070	regulator of competence-specific genes
ADJ80_RS06760	COG0436	Aminotransferase
ADJ80_RS06770	COG0745	RESPONSE REGULATOR receiver
ADJ80_RS06775	COG0642	Histidine kinase
ADJ80_RS06785	COG2814	Major facilitator Superfamily
ADJ80_RS06790	COG0375	protein maturation
ADJ80_RS06800	COG2252	PERMEase
ADJ80_RS06815	COG0825	malonyl-CoA metabolic process
ADJ80_RS06835	COG3069	C4-dicarboxylate transmembrane transporter activity
ADJ80_RS06840	COG2233	PERMEase
ADJ80_RS06885	COG0516	GMP reductase activity
ADJ80_RS06885	COG0517	IMP dehydrogenase activity
ADJ80_RS06890	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ADJ80_RS06890	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ADJ80_RS06905	COG0351	phosphomethylpyrimidine kinase
ADJ80_RS06910	COG4143	(ABC) transporter
ADJ80_RS06915	COG1178	ABC-type Fe3 transport system permease component
ADJ80_RS06920	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ADJ80_RS06930	COG1914	H( )-stimulated, divalent metal cation uptake system
ADJ80_RS06940	COG1984	allophanate hydrolase subunit 2
ADJ80_RS06945	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ADJ80_RS06950	COG2190	(PTS) system
ADJ80_RS06950	COG1263	PTS System
ADJ80_RS06950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADJ80_RS06960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADJ80_RS06960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADJ80_RS06965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADJ80_RS06970	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ADJ80_RS06980	COG1737	Transcriptional regulator
ADJ80_RS06985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADJ80_RS06990	COG0363	glucosamine-6-phosphate deaminase activity
ADJ80_RS06995	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ADJ80_RS07000	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ADJ80_RS07015	COG0247	lactate metabolic process
ADJ80_RS07015	COG0277	FAD linked oxidase domain protein
ADJ80_RS07025	COG1704	LemA family
ADJ80_RS07050	COG2363	Small membrane protein
ADJ80_RS07055	COG1643	Atp-dependent helicase
ADJ80_RS07080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADJ80_RS07085	COG1136	(ABC) transporter
ADJ80_RS07085	COG0577	efflux transmembrane transporter activity
ADJ80_RS07095	COG0577	efflux transmembrane transporter activity
ADJ80_RS07110	COG0672	)-iron permease
ADJ80_RS07115	COG1556	Lactate utilization protein
ADJ80_RS07120	COG1139	Iron-sulfur cluster binding protein
ADJ80_RS07125	COG0247	lactate metabolic process
ADJ80_RS07130	COG1620	l-lactate permease
ADJ80_RS07135	COG0277	FAD linked oxidase domain protein
ADJ80_RS07140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ADJ80_RS07145	COG3112	Uncharacterised protein family (UPF0231)
ADJ80_RS07150	COG0316	Belongs to the HesB IscA family
ADJ80_RS07155	COG0024	Methionine aminopeptidase
ADJ80_RS07165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ADJ80_RS07170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADJ80_RS07215	COG3787	Belongs to the UPF0306 family
ADJ80_RS07220	COG4172	Belongs to the ABC transporter superfamily
ADJ80_RS07225	COG4172	Belongs to the ABC transporter superfamily
ADJ80_RS07230	COG4171	peptide transport system, permease
ADJ80_RS07235	COG4168	peptide transport system, permease
ADJ80_RS07240	COG4166	transmembrane transport
ADJ80_RS07245	COG1120	ATPase activity
ADJ80_RS07255	COG3106	COG3106 Predicted ATPase
ADJ80_RS07265	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ADJ80_RS07270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADJ80_RS07285	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ADJ80_RS07290	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADJ80_RS07290	COG1388	LysM domain
ADJ80_RS07295	COG0802	atpase or kinase
ADJ80_RS07300	COG2194	sulfuric ester hydrolase activity
ADJ80_RS07320	COG1162	GTPase activity
ADJ80_RS07325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADJ80_RS07330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADJ80_RS07335	COG2190	(PTS) system
ADJ80_RS07340	COG0339	signal peptide processing
ADJ80_RS07345	COG2832	Protein of unknown function (DUF454)
ADJ80_RS07350	COG4166	transmembrane transport
ADJ80_RS07360	COG0671	phosphoesterase, PA-phosphatase related
ADJ80_RS07365	COG1940	carbohydrate kinase activity
ADJ80_RS07370	COG1216	Glycosyl transferase, family 2
ADJ80_RS07375	COG2951	lytic endotransglycosylase activity
ADJ80_RS07385	COG0510	thiamine kinase activity
ADJ80_RS07390	COG3475	LICD family
ADJ80_RS07425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ADJ80_RS07430	COG0708	Exodeoxyribonuclease III
ADJ80_RS07435	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ADJ80_RS07440	COG1088	dTDP-glucose 4,6-dehydratase activity
ADJ80_RS07450	COG0778	Nitroreductase
ADJ80_RS07455	COG0616	signal peptide processing
ADJ80_RS07460	COG1605	Chorismate mutase
ADJ80_RS07460	COG0287	Prephenate dehydrogenase
ADJ80_RS07465	COG0009	L-threonylcarbamoyladenylate synthase
ADJ80_RS07475	COG0583	DNA-binding transcription factor activity
ADJ80_RS07490	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ADJ80_RS07495	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADJ80_RS07500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADJ80_RS07510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADJ80_RS07520	COG0512	Glutamine amidotransferase of anthranilate synthase
ADJ80_RS07525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADJ80_RS07530	COG4206	TonB-dependent receptor
ADJ80_RS07540	COG1943	Transposase
ADJ80_RS07545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADJ80_RS07575	COG0556	nucleotide-excision repair
ADJ80_RS07585	COG0646	methionine synthase
ADJ80_RS07585	COG1410	methionine synthase
ADJ80_RS07590	COG4591	ABC-type transport system involved in lipoprotein release permease component
ADJ80_RS07595	COG1136	(ABC) transporter
ADJ80_RS07600	COG4591	ABC-type transport system involved in lipoprotein release permease component
ADJ80_RS07605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ADJ80_RS07610	COG0305	Participates in initiation and elongation during chromosome replication
ADJ80_RS07625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ADJ80_RS07635	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ADJ80_RS07640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ADJ80_RS07645	COG1280	lysine exporter protein (LysE YggA)
ADJ80_RS07655	COG0633	Ferredoxin
ADJ80_RS07660	COG0471	metal ion transport
ADJ80_RS07665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADJ80_RS07675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADJ80_RS07685	COG1840	ABC-type Fe3 transport system, periplasmic component
ADJ80_RS07695	COG3842	ATPase activity
ADJ80_RS07700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADJ80_RS07705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADJ80_RS07710	COG3955	Domain of unknown function (DUF1919)
ADJ80_RS07715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADJ80_RS07720	COG0785	Cytochrome C biogenesis protein
ADJ80_RS07725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADJ80_RS07725	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADJ80_RS07730	COG0288	reversible hydration of carbon dioxide
ADJ80_RS07735	COG2823	Periplasmic or secreted lipoprotein
ADJ80_RS07740	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ADJ80_RS07745	COG0792	nuclease activity
ADJ80_RS07755	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ADJ80_RS07760	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ADJ80_RS07765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ADJ80_RS07770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ADJ80_RS07780	COG0616	signal peptide processing
ADJ80_RS07810	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ADJ80_RS07815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADJ80_RS07820	COG3738	Protein conserved in bacteria
ADJ80_RS07830	COG0142	geranyltranstransferase activity
ADJ80_RS07840	COG2819	hydrolase of the alpha beta superfamily
ADJ80_RS07850	COG0285	dihydrofolate synthase activity
ADJ80_RS07855	COG0406	alpha-ribazole phosphatase activity
ADJ80_RS07860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADJ80_RS07865	COG2431	L-lysine efflux transmembrane transporter activity
ADJ80_RS07870	COG0564	pseudouridine synthase activity
ADJ80_RS07880	COG2824	Alkylphosphonate utilization operon protein PhnA
ADJ80_RS07895	COG1538	Outer membrane efflux protein
ADJ80_RS07900	COG1136	(ABC) transporter
ADJ80_RS07900	COG0577	efflux transmembrane transporter activity
ADJ80_RS07905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADJ80_RS07920	COG1640	4-alpha-glucanotransferase
ADJ80_RS07930	COG1523	belongs to the glycosyl hydrolase 13 family
ADJ80_RS07945	COG0058	SHG alpha-glucan phosphorylase activity
ADJ80_RS07955	COG0586	Pfam SNARE associated Golgi protein
ADJ80_RS07970	COG1686	Belongs to the peptidase S11 family
ADJ80_RS07990	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ADJ80_RS07995	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ADJ80_RS08000	COG0697	spore germination
ADJ80_RS08005	COG2925	Exonuclease
ADJ80_RS08010	COG1528	Iron-storage protein
ADJ80_RS08015	COG1528	Iron-storage protein
ADJ80_RS08020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADJ80_RS08025	COG0589	response to stress
ADJ80_RS08030	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
ADJ80_RS08040	COG0583	DNA-binding transcription factor activity
ADJ80_RS08045	COG0613	PHP domain protein
ADJ80_RS08060	COG0308	aminopeptidase N
ADJ80_RS08065	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADJ80_RS08070	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ADJ80_RS08075	COG1448	Aminotransferase
ADJ80_RS08080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADJ80_RS08085	COG1120	ATPase activity
ADJ80_RS08095	COG3585	molybdate ion transport
ADJ80_RS08100	COG1309	transcriptional regulator
ADJ80_RS08105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADJ80_RS08110	COG1129	ABC transporter
ADJ80_RS08110	COG0842	Transport permease protein
ADJ80_RS08115	COG0842	Transport permease protein
ADJ80_RS08135	COG0791	NLP P60 protein
ADJ80_RS08150	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ADJ80_RS08165	COG0517	IMP dehydrogenase activity
ADJ80_RS08165	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ADJ80_RS08170	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ADJ80_RS08175	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADJ80_RS08180	COG0512	Glutamine amidotransferase of anthranilate synthase
ADJ80_RS08185	COG1942	4-Oxalocrotonate Tautomerase
ADJ80_RS08195	COG0134	indole-3-glycerol-phosphate synthase activity
ADJ80_RS08195	COG0135	phosphoribosylanthranilate isomerase activity
ADJ80_RS08200	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ADJ80_RS08205	COG0437	4 iron, 4 sulfur cluster binding
ADJ80_RS08210	COG5557	Pfam Polysulphide reductase, NrfD
ADJ80_RS08215	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ADJ80_RS08220	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ADJ80_RS08225	COG1773	rubredoxin
ADJ80_RS08230	COG0298	carbon dioxide binding
ADJ80_RS08240	COG3630	sodium ion export across plasma membrane
ADJ80_RS08245	COG0511	ligase activity, forming carbon-carbon bonds
ADJ80_RS08245	COG5016	pyruvate
ADJ80_RS08255	COG4221	oxidoreductase activity
ADJ80_RS08260	COG0133	tryptophan synthase activity
ADJ80_RS08270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADJ80_RS08280	COG0469	pyruvate kinase activity
ADJ80_RS08290	COG1940	carbohydrate kinase activity
ADJ80_RS08300	COG2969	positive regulation of protein catabolic process
ADJ80_RS08310	COG0314	molybdopterin synthase activity
ADJ80_RS08315	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ADJ80_RS08325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADJ80_RS08345	COG3005	denitrification pathway
ADJ80_RS08350	COG0243	molybdopterin cofactor binding
ADJ80_RS08360	COG2315	Protein conserved in bacteria
ADJ80_RS08375	COG0366	Alpha amylase catalytic
ADJ80_RS08380	COG1263	PTS System
ADJ80_RS08380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADJ80_RS08385	COG0101	tRNA pseudouridine synthase activity
ADJ80_RS08410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ADJ80_RS08415	COG1074	ATP-dependent DNA helicase activity
ADJ80_RS08420	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ADJ80_RS08425	COG2252	PERMEase
ADJ80_RS08445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ADJ80_RS08450	COG1067	ATP-dependent peptidase activity
ADJ80_RS08460	COG1278	Cold shock
ADJ80_RS08475	COG3098	single-species biofilm formation
ADJ80_RS08480	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ADJ80_RS08485	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ADJ80_RS08485	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ADJ80_RS08490	COG3101	peptidyl-lysine hydroxylation
ADJ80_RS08495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADJ80_RS08505	COG0788	formyltetrahydrofolate deformylase activity
ADJ80_RS08510	COG2916	Histone family protein nucleoid-structuring protein H-NS
ADJ80_RS08515	COG1757	Na H antiporter
ADJ80_RS08520	COG0028	Belongs to the TPP enzyme family
ADJ80_RS08525	COG0440	acetolactate synthase activity
ADJ80_RS08550	COG2949	membrane
ADJ80_RS08555	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADJ80_RS08570	COG3099	Belongs to the UPF0263 family
ADJ80_RS08575	COG4178	(ABC) transporter
ADJ80_RS08580	COG4774	siderophore transport
ADJ80_RS08590	COG0307	riboflavin synthase, alpha
ADJ80_RS08595	COG1534	Rna-binding protein
ADJ80_RS08600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADJ80_RS08605	COG2027	D-alanyl-D-alanine carboxypeptidase
ADJ80_RS08615	COG0303	'Molybdopterin
ADJ80_RS08620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ADJ80_RS08630	COG4580	involved in the transport of maltose and maltodextrins
ADJ80_RS08640	COG3842	ATPase activity
ADJ80_RS08650	COG2182	Extracellular solute-binding protein
ADJ80_RS08655	COG1175	transmembrane transport
ADJ80_RS08660	COG3833	ABC-type maltose transport systems, permease component
ADJ80_RS08665	COG0366	Alpha amylase catalytic
ADJ80_RS08740	COG2909	trisaccharide binding
ADJ80_RS08745	COG0058	SHG alpha-glucan phosphorylase activity
ADJ80_RS08750	COG1640	4-alpha-glucanotransferase
ADJ80_RS08760	COG0163	prenyltransferase activity
ADJ80_RS08770	COG1286	toxin biosynthetic process
ADJ80_RS08780	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADJ80_RS08785	COG0857	belongs to the CobB CobQ family
ADJ80_RS08785	COG0280	phosphate acetyltransferase
ADJ80_RS08795	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ADJ80_RS08800	COG0617	tRNA 3'-terminal CCA addition
ADJ80_RS08805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ADJ80_RS08810	COG2333	competence protein COMEC
ADJ80_RS08810	COG0658	competence protein
ADJ80_RS08815	COG1132	(ABC) transporter
ADJ80_RS08820	COG1663	tetraacyldisaccharide 4'-kinase activity
ADJ80_RS08825	COG2835	tetraacyldisaccharide 4'-kinase activity
ADJ80_RS08835	COG0322	excinuclease ABC activity
ADJ80_RS08865	COG1176	ABC-type spermidine putrescine transport system, permease component I
ADJ80_RS08875	COG3842	ATPase activity
ADJ80_RS08885	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ADJ80_RS08890	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ADJ80_RS08905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADJ80_RS08930	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ADJ80_RS08940	COG0195	Participates in both transcription termination and antitermination
ADJ80_RS08955	COG3100	YcgL domain-containing protein
ADJ80_RS08970	COG2062	phosphohistidine phosphatase, SixA
ADJ80_RS08980	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ADJ80_RS08985	COG2962	Rard protein
ADJ80_RS08990	COG1522	sequence-specific DNA binding
ADJ80_RS08995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ADJ80_RS09010	COG2932	Transcriptional regulator
ADJ80_RS09015	COG0791	NLP P60 protein
ADJ80_RS09025	COG2890	protein-(glutamine-N5) methyltransferase activity
ADJ80_RS09035	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADJ80_RS09040	COG3133	Outer membrane lipoprotein
ADJ80_RS09045	COG3102	Protein conserved in bacteria
ADJ80_RS09055	COG5339	Protein conserved in bacteria
ADJ80_RS09060	COG0443	Heat shock 70 kDa protein
ADJ80_RS09065	COG0484	heat shock protein binding
ADJ80_RS09120	COG0626	cystathionine gamma-synthase activity
ADJ80_RS09125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADJ80_RS09145	COG2267	carboxylic ester hydrolase activity
ADJ80_RS09160	COG1858	cytochrome C peroxidase
ADJ80_RS09165	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ADJ80_RS09170	COG0318	PFAM AMP-dependent synthetase and ligase
ADJ80_RS09175	COG3065	identical protein binding
ADJ80_RS09180	COG1214	PFAM Peptidase M22, glycoprotease
ADJ80_RS09185	COG1199	ATP-dependent helicase activity
ADJ80_RS09190	COG0676	glucose-6-phosphate 1-epimerase activity
ADJ80_RS09200	COG3384	dioxygenase
ADJ80_RS09205	COG2249	NAD(P)H dehydrogenase (quinone) activity
ADJ80_RS09215	COG0281	malic enzyme
ADJ80_RS09225	COG0583	DNA-binding transcription factor activity
ADJ80_RS09245	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ADJ80_RS09255	COG3118	belongs to the thioredoxin family
ADJ80_RS09260	COG0492	ferredoxin-NADP+ reductase activity
ADJ80_RS09265	COG4988	ABC transporter
ADJ80_RS09270	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ADJ80_RS09275	COG1946	Acyl-CoA thioesterase
ADJ80_RS09280	COG0515	serine threonine protein kinase
ADJ80_RS09295	COG1216	Glycosyl transferase, family 2
ADJ80_RS09305	COG3306	glycosyltransferase involved in LPS biosynthesis
ADJ80_RS09315	COG5039	Polysaccharide pyruvyl transferase
ADJ80_RS09320	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ADJ80_RS09325	COG1793	dna ligase
ADJ80_RS09335	COG0210	DNA helicase
ADJ80_RS09340	COG2610	gluconate transmembrane transporter activity
ADJ80_RS09345	COG3265	gluconokinase activity
ADJ80_RS09350	COG1609	Transcriptional regulator
ADJ80_RS09370	COG0437	4 iron, 4 sulfur cluster binding
ADJ80_RS09375	COG2864	formate dehydrogenase
ADJ80_RS09380	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ADJ80_RS09385	COG4149	molybdate abc transporter
ADJ80_RS09390	COG0725	ABC transporter, periplasmic molybdate-binding protein
ADJ80_RS09395	COG2005	Transcriptional regulator
ADJ80_RS09405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADJ80_RS09410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADJ80_RS09410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADJ80_RS09415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADJ80_RS09425	COG0583	DNA-binding transcription factor activity
ADJ80_RS09430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADJ80_RS09440	COG1438	arginine binding
ADJ80_RS09445	COG1090	epimerase
ADJ80_RS09450	COG4657	Part of a membrane complex involved in electron transport
ADJ80_RS09460	COG4656	Part of a membrane complex involved in electron transport
ADJ80_RS09480	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADJ80_RS09485	COG0733	neurotransmitter:sodium symporter activity
ADJ80_RS09495	COG3959	Transketolase, thiamine diphosphate binding domain
ADJ80_RS09515	COG0488	(ABC) transporter
ADJ80_RS09525	COG1346	cytolysis
ADJ80_RS09535	COG0425	Belongs to the sulfur carrier protein TusA family
ADJ80_RS09540	COG2391	methyltransferase activity
ADJ80_RS09545	COG2391	methyltransferase activity
ADJ80_RS09580	COG1525	nuclease
ADJ80_RS09585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ADJ80_RS09590	COG2166	iron-sulfur cluster assembly
ADJ80_RS09595	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ADJ80_RS09595	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ADJ80_RS09600	COG1560	Kdo2-lipid A biosynthetic process
ADJ80_RS09605	COG3381	protein complex oligomerization
ADJ80_RS09610	COG2249	NAD(P)H dehydrogenase (quinone) activity
ADJ80_RS09620	COG0330	HflC and HflK could
ADJ80_RS09625	COG0737	Belongs to the 5'-nucleotidase family
ADJ80_RS09630	COG4607	ABC-type enterochelin transport system periplasmic component
ADJ80_RS09635	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADJ80_RS09640	COG4605	iron ion homeostasis
ADJ80_RS09645	COG4604	ABC transporter, ATP-binding protein
ADJ80_RS09650	COG3383	formate dehydrogenase (NAD+) activity
ADJ80_RS09655	COG3383	formate dehydrogenase (NAD+) activity
ADJ80_RS09665	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ADJ80_RS09675	COG3260	NADH ubiquinone oxidoreductase 20
ADJ80_RS09685	COG3261	NADH dehydrogenase
ADJ80_RS09685	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ADJ80_RS09690	COG0651	ATP synthesis coupled electron transport
ADJ80_RS09695	COG4237	Hydrogenase 4 membrane
ADJ80_RS09700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADJ80_RS09705	COG0650	Formate hydrogenlyase subunit 4
ADJ80_RS09710	COG0651	ATP synthesis coupled electron transport
ADJ80_RS09715	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADJ80_RS09720	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ADJ80_RS09725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADJ80_RS09750	COG0309	Hydrogenase expression formation protein (HypE)
ADJ80_RS09755	COG0409	Hydrogenase expression formation protein
ADJ80_RS09760	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ADJ80_RS09765	COG1122	ATPase activity
ADJ80_RS09770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADJ80_RS09775	COG0310	cobalt ion transport
ADJ80_RS09780	COG0310	cobalt ion transport
ADJ80_RS09785	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
ADJ80_RS09790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ADJ80_RS09795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADJ80_RS09800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ADJ80_RS09805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADJ80_RS09865	COG1840	ABC-type Fe3 transport system, periplasmic component
ADJ80_RS09870	COG1840	ABC-type Fe3 transport system, periplasmic component
ADJ80_RS09895	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ADJ80_RS09900	COG1959	2 iron, 2 sulfur cluster binding
ADJ80_RS09910	COG0822	iron-sulfur transferase activity
ADJ80_RS09920	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ADJ80_RS09925	COG0443	Heat shock 70 kDa protein
ADJ80_RS09930	COG0633	Ferredoxin
ADJ80_RS09935	COG2975	iron-sulfur cluster assembly
ADJ80_RS09940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADJ80_RS09940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADJ80_RS09945	COG0489	protein tyrosine kinase activity
ADJ80_RS09950	COG3683	transport system, periplasmic component
ADJ80_RS09955	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ADJ80_RS09970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADJ80_RS09975	COG0488	(ABC) transporter
ADJ80_RS09985	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
ADJ80_RS09990	COG1858	cytochrome C peroxidase
ADJ80_RS09995	COG0187	DNA topoisomerase II activity
ADJ80_RS10000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADJ80_RS10005	COG0783	Belongs to the Dps family
ADJ80_RS10010	COG1566	PFAM secretion protein HlyD family protein
ADJ80_RS10015	COG2814	Major facilitator Superfamily
ADJ80_RS10020	COG1840	ABC-type Fe3 transport system, periplasmic component
ADJ80_RS10030	COG3550	peptidyl-serine autophosphorylation
ADJ80_RS10060	COG2927	DNA polymerase III (CHI subunit)
ADJ80_RS10065	COG0114	fumarate hydratase activity
ADJ80_RS10070	COG2268	Band 7 protein
ADJ80_RS10085	COG0778	Nitroreductase
ADJ80_RS10090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ADJ80_RS10135	COG1136	(ABC) transporter
ADJ80_RS10165	COG0814	amino acid
ADJ80_RS10190	COG2926	Belongs to the UPF0265 family
ADJ80_RS10205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ADJ80_RS10210	COG2017	converts alpha-aldose to the beta-anomer
ADJ80_RS10215	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ADJ80_RS10220	COG1085	galactose-1-phosphate uridylyltransferase
ADJ80_RS10225	COG1609	Transcriptional regulator
ADJ80_RS10230	COG1879	ABC-type sugar transport system periplasmic component
ADJ80_RS10235	COG1129	ABC transporter
ADJ80_RS10240	COG4211	Belongs to the binding-protein-dependent transport system permease family
ADJ80_RS10245	COG2198	Histidine kinase
ADJ80_RS10245	COG5002	protein histidine kinase activity
ADJ80_RS10245	COG0784	Response regulator, receiver
ADJ80_RS10250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADJ80_RS10255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADJ80_RS10255	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ADJ80_RS10260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ADJ80_RS10270	COG0497	DNA recombination
ADJ80_RS10285	COG1607	acyl-coa hydrolase
ADJ80_RS10290	COG2350	Protein conserved in bacteria
ADJ80_RS10295	COG0741	lytic transglycosylase activity
ADJ80_RS10305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ADJ80_RS10325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADJ80_RS10330	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ADJ80_RS10340	COG1408	metallophosphoesterase
ADJ80_RS10345	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ADJ80_RS10350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADJ80_RS10355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADJ80_RS10360	COG1120	ATPase activity
ADJ80_RS10370	COG1053	succinate dehydrogenase
ADJ80_RS10375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADJ80_RS10385	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ADJ80_RS10390	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADJ80_RS10390	COG0506	proline dehydrogenase activity
ADJ80_RS10390	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADJ80_RS10405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADJ80_RS10410	COG0343	queuine tRNA-ribosyltransferase activity
ADJ80_RS10415	COG3945	hemerythrin HHE cation binding domain
ADJ80_RS10425	COG1862	Preprotein translocase
ADJ80_RS10430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADJ80_RS10435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADJ80_RS10440	COG1454	alcohol dehydrogenase
ADJ80_RS10440	COG1012	belongs to the aldehyde dehydrogenase family
ADJ80_RS10445	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADJ80_RS10450	COG1129	ABC transporter
ADJ80_RS10465	COG0673	inositol 2-dehydrogenase activity
ADJ80_RS10495	COG0151	Belongs to the GarS family
ADJ80_RS10500	COG0138	bifunctional purine biosynthesis protein purh
ADJ80_RS10515	COG2813	Specifically methylates the guanine in position
ADJ80_RS10520	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ADJ80_RS10525	COG0456	acetyltransferase
ADJ80_RS10530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ADJ80_RS10545	COG4795	General secretion pathway protein
ADJ80_RS10550	COG2165	general secretion pathway protein
ADJ80_RS10580	COG3064	Membrane
ADJ80_RS10585	COG0848	biopolymer transport protein
ADJ80_RS10590	COG0811	peptide transport
ADJ80_RS10595	COG0824	Thioesterase
ADJ80_RS10605	COG1294	oxidase, subunit
ADJ80_RS10610	COG1271	oxidase subunit
ADJ80_RS10625	COG0632	four-way junction helicase activity
ADJ80_RS10645	COG0494	nUDIX hydrolase
ADJ80_RS10655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ADJ80_RS10670	COG2271	Major facilitator Superfamily
ADJ80_RS10685	COG0346	lactoylglutathione lyase activity
ADJ80_RS10695	COG2056	Na+-H+ antiporter family
ADJ80_RS10710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADJ80_RS10715	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ADJ80_RS10725	COG0142	geranyltranstransferase activity
ADJ80_RS10740	COG0697	spore germination
ADJ80_RS10745	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADJ80_RS10760	COG4166	transmembrane transport
ADJ80_RS10765	COG0601	transmembrane transport
ADJ80_RS10770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADJ80_RS10775	COG0444	Belongs to the ABC transporter superfamily
ADJ80_RS10780	COG4608	Belongs to the ABC transporter superfamily
ADJ80_RS10785	COG0745	RESPONSE REGULATOR receiver
ADJ80_RS10790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ADJ80_RS10810	COG2259	Doxx family
ADJ80_RS10820	COG1530	ribonuclease E activity
ADJ80_RS10835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADJ80_RS10840	COG0626	cystathionine gamma-synthase activity
ADJ80_RS10860	COG0527	aspartate kinase activity
ADJ80_RS10875	COG5295	Hep Hag repeat protein
ADJ80_RS10885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADJ80_RS10895	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ADJ80_RS10900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ADJ80_RS10905	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ADJ80_RS10910	COG0475	glutathione-regulated potassium exporter activity
ADJ80_RS10910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ADJ80_RS10915	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ADJ80_RS10945	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ADJ80_RS10950	COG3161	chorismate lyase activity
ADJ80_RS10960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADJ80_RS10965	COG1758	RNA polymerase activity
ADJ80_RS10975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADJ80_RS10985	COG2867	negative regulation of translational initiation
ADJ80_RS10995	COG2850	peptidyl-arginine hydroxylation
ADJ80_RS11010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADJ80_RS11015	COG1137	ATPase activity
ADJ80_RS11020	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ADJ80_RS11025	COG3117	lipopolysaccharide transmembrane transporter activity
ADJ80_RS11030	COG1127	ABC transporter
ADJ80_RS11035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ADJ80_RS11040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ADJ80_RS11045	COG2854	intermembrane phospholipid transfer
ADJ80_RS11050	COG3113	response to antibiotic
ADJ80_RS11055	COG5007	Belongs to the BolA IbaG family
ADJ80_RS11065	COG3028	Belongs to the UPF0307 family
ADJ80_RS11070	COG0312	modulator of DNA gyrase
ADJ80_RS11075	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ADJ80_RS11080	COG1929	Belongs to the glycerate kinase type-1 family
ADJ80_RS11085	COG2610	gluconate transmembrane transporter activity
ADJ80_RS11090	COG3835	regulator
ADJ80_RS11105	COG0438	transferase activity, transferring glycosyl groups
ADJ80_RS11110	COG1132	(ABC) transporter
ADJ80_RS11120	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ADJ80_RS11125	COG0513	Belongs to the DEAD box helicase family
ADJ80_RS11130	COG4785	May be involved in cell division