locus-tag	class	description
EML485_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EML485_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EML485_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EML485_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EML485_RS00025	COG1420	regulation of RNA biosynthetic process
EML485_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EML485_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EML485_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EML485_RS00050	COG1137	ATPase activity
EML485_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EML485_RS00065	COG0616	signal peptide processing
EML485_RS00070	COG0776	regulation of translation
EML485_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EML485_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EML485_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EML485_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EML485_RS00115	COG0728	peptidoglycan biosynthetic process
EML485_RS00125	COG0180	Tryptophanyl-tRNA synthetase
EML485_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EML485_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EML485_RS00165	COG1702	phosphate starvation-inducible protein PhoH
EML485_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EML485_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EML485_RS00185	COG1396	sequence-specific DNA binding
EML485_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EML485_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EML485_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML485_RS00210	COG0242	peptide deformylase activity
EML485_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EML485_RS00220	COG0101	tRNA pseudouridine synthase activity
EML485_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML485_RS00235	COG2171	N-acyltransferase activity
EML485_RS00245	COG0840	transmembrane signaling receptor activity
EML485_RS00255	COG0071	Belongs to the small heat shock protein (HSP20) family
EML485_RS00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EML485_RS00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EML485_RS00295	COG0706	membrane insertase activity
EML485_RS00300	COG0594	ribonuclease P activity
EML485_RS00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EML485_RS00310	COG0840	transmembrane signaling receptor activity
EML485_RS00315	COG3850	Histidine kinase
EML485_RS00315	COG5002	protein histidine kinase activity
EML485_RS00325	COG2226	methyltransferase
EML485_RS00330	COG3842	ATPase activity
EML485_RS00335	COG1175	transmembrane transport
EML485_RS00340	COG0395	ABC-type sugar transport system, permease component
EML485_RS00355	COG0427	acetyl-CoA hydrolase
EML485_RS00365	COG3938	Belongs to the proline racemase family
EML485_RS00370	COG0418	dihydroorotase activity
EML485_RS00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EML485_RS00395	COG0166	Belongs to the GPI family
EML485_RS00400	COG0318	PFAM AMP-dependent synthetase and ligase
EML485_RS00405	COG3842	ATPase activity
EML485_RS00410	COG1840	ABC-type Fe3 transport system, periplasmic component
EML485_RS00415	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EML485_RS00420	COG4774	siderophore transport
EML485_RS00460	COG2326	polyphosphate kinase activity
EML485_RS00465	COG5002	protein histidine kinase activity
EML485_RS00470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EML485_RS00475	COG0573	inorganic phosphate transmembrane transporter activity
EML485_RS00485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EML485_RS00490	COG0704	Plays a role in the regulation of phosphate uptake
EML485_RS00495	COG0745	RESPONSE REGULATOR receiver
EML485_RS00505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EML485_RS00510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EML485_RS00520	COG2967	ApaG domain
EML485_RS00530	COG0717	Belongs to the dCTP deaminase family
EML485_RS00765	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EML485_RS00785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EML485_RS00835	COG0167	dihydroorotate dehydrogenase activity
EML485_RS00850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EML485_RS00870	COG1959	2 iron, 2 sulfur cluster binding
EML485_RS00875	COG1201	RNA secondary structure unwinding
EML485_RS00895	COG0730	response to heat
EML485_RS00905	COG1960	acyl-CoA dehydrogenase activity
EML485_RS00910	COG0183	Belongs to the thiolase family
EML485_RS00915	COG1024	Enoyl-CoA hydratase
EML485_RS00915	COG1250	3-hydroxyacyl-CoA dehydrogenase
EML485_RS00935	COG1320	monovalent cation:proton antiporter activity
EML485_RS00940	COG2212	antiporter activity
EML485_RS00945	COG1863	multisubunit Na H antiporter MnhE subunit
EML485_RS00950	COG0651	ATP synthesis coupled electron transport
EML485_RS00955	COG1006	Multisubunit Na H antiporter MnhC subunit
EML485_RS00960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EML485_RS00960	COG2111	Na H antiporter
EML485_RS00970	COG0840	transmembrane signaling receptor activity
EML485_RS00980	COG0745	RESPONSE REGULATOR receiver
EML485_RS00985	COG0643	Histidine kinase
EML485_RS00985	COG2198	Histidine kinase
EML485_RS00990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EML485_RS00995	COG2201	protein-glutamate methylesterase activity
EML485_RS01000	COG0745	RESPONSE REGULATOR receiver
EML485_RS01005	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EML485_RS01015	COG1766	The M ring may be actively involved in energy transduction
EML485_RS01020	COG2771	luxR family
EML485_RS01030	COG2972	Histidine kinase
EML485_RS01030	COG0840	transmembrane signaling receptor activity
EML485_RS01035	COG2205	protein histidine kinase activity
EML485_RS01035	COG2198	Histidine kinase
EML485_RS01035	COG0784	Response regulator, receiver
EML485_RS01040	COG1970	mechanosensitive ion channel activity
EML485_RS01045	COG0436	Aminotransferase
EML485_RS01060	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EML485_RS01065	COG0424	maF-like protein
EML485_RS01070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EML485_RS01080	COG5328	Belongs to the UPF0262 family
EML485_RS01085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EML485_RS01095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EML485_RS01110	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EML485_RS01130	COG1338	Plays a role in the flagellum-specific transport system
EML485_RS01140	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EML485_RS01150	COG1706	bacterial-type flagellum-dependent cell motility
EML485_RS01155	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EML485_RS01160	COG4786	Flagellar basal body rod
EML485_RS01165	COG1677	Flagellar hook-basal body complex protein FliE
EML485_RS01170	COG1558	bacterial-type flagellum-dependent cell motility
EML485_RS01175	COG1815	bacterial-type flagellum-dependent cell motility
EML485_RS01185	COG1157	protein secretion by the type III secretion system
EML485_RS01190	COG4786	Flagellar basal body rod
EML485_RS01200	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EML485_RS01205	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EML485_RS01210	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EML485_RS01215	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EML485_RS01220	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EML485_RS01240	COG1360	Flagellar Motor Protein
EML485_RS01265	COG1749	Flagellar hook protein flgE
EML485_RS01285	COG5443	negative regulation of bacterial-type flagellum assembly
EML485_RS01290	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EML485_RS01300	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EML485_RS01340	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EML485_RS01345	COG1609	Transcriptional regulator
EML485_RS01350	COG1653	transport
EML485_RS01355	COG1175	transmembrane transport
EML485_RS01360	COG0395	ABC-type sugar transport system, permease component
EML485_RS01365	COG0366	Alpha amylase catalytic
EML485_RS01370	COG3842	ATPase activity
EML485_RS01385	COG0129	dihydroxy-acid dehydratase activity
EML485_RS01390	COG0363	glucosamine-6-phosphate deaminase activity
EML485_RS01395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EML485_RS01400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS01410	COG2081	HI0933 family
EML485_RS01425	COG2224	Isocitrate lyase
EML485_RS01440	COG3842	ATPase activity
EML485_RS01445	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML485_RS01450	COG1177	transmembrane transport
EML485_RS01460	COG2205	protein histidine kinase activity
EML485_RS01470	COG0248	Ppx GppA phosphatase
EML485_RS01475	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EML485_RS01480	COG0477	Major facilitator Superfamily
EML485_RS01525	COG0521	Mo-molybdopterin cofactor biosynthetic process
EML485_RS01530	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EML485_RS01540	COG0142	geranyltranstransferase activity
EML485_RS01565	COG0752	glycyl-tRNA synthetase alpha subunit
EML485_RS01575	COG1704	LemA family
EML485_RS01580	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EML485_RS01590	COG0751	glycine-tRNA ligase activity
EML485_RS01595	COG1683	Conserved Protein
EML485_RS01600	COG0840	transmembrane signaling receptor activity
EML485_RS01610	COG0151	Belongs to the GarS family
EML485_RS01615	COG2183	response to ionizing radiation
EML485_RS01620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EML485_RS01630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EML485_RS01645	COG0583	DNA-binding transcription factor activity
EML485_RS01665	COG0306	phosphate transporter
EML485_RS01675	COG0561	phosphatase activity
EML485_RS01680	COG0438	transferase activity, transferring glycosyl groups
EML485_RS01685	COG2186	Transcriptional regulator
EML485_RS01695	COG0583	DNA-binding transcription factor activity
EML485_RS01700	COG0277	FAD linked oxidase domain protein
EML485_RS01705	COG0277	FAD linked oxidase domain protein
EML485_RS01710	COG0247	lactate metabolic process
EML485_RS01720	COG1376	ErfK ybiS ycfS ynhG family protein
EML485_RS01725	COG0519	Catalyzes the synthesis of GMP from XMP
EML485_RS01735	COG2855	membrane
EML485_RS01740	COG0583	DNA-binding transcription factor activity
EML485_RS01760	COG0124	histidyl-tRNA synthetase
EML485_RS01770	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EML485_RS01775	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EML485_RS01780	COG2259	Doxx family
EML485_RS01790	COG0459	protein refolding
EML485_RS01795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EML485_RS01805	COG0196	riboflavin kinase activity
EML485_RS01810	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EML485_RS01820	COG0590	tRNA wobble adenosine to inosine editing
EML485_RS01825	COG1187	pseudouridine synthase activity
EML485_RS01830	COG0742	ribosomal rna small subunit methyltransferase
EML485_RS01835	COG1752	Esterase of the alpha-beta hydrolase superfamily
EML485_RS01845	COG0312	modulator of DNA gyrase
EML485_RS01850	COG0483	inositol monophosphate 1-phosphatase activity
EML485_RS01870	COG1663	tetraacyldisaccharide 4'-kinase activity
EML485_RS01880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EML485_RS01890	COG5001	Diguanylate cyclase
EML485_RS01890	COG3300	MHYT domain
EML485_RS01895	COG3386	PFAM SMP-30 Gluconolaconase
EML485_RS01900	COG0800	Aldolase
EML485_RS01905	COG3734	2-keto-3-deoxy-galactonokinase
EML485_RS01910	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS01920	COG2197	response regulator
EML485_RS01925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML485_RS01935	COG0598	Magnesium transport protein CorA
EML485_RS01940	COG3158	transport of potassium into the cell
EML485_RS01955	COG0356	it plays a direct role in the translocation of protons across the membrane
EML485_RS01965	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EML485_RS01970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EML485_RS01985	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EML485_RS02005	COG0009	L-threonylcarbamoyladenylate synthase
EML485_RS02015	COG4638	Rieske (2fe-2S)
EML485_RS02040	COG1960	acyl-CoA dehydrogenase activity
EML485_RS02055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EML485_RS02060	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EML485_RS02065	COG0840	transmembrane signaling receptor activity
EML485_RS02105	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EML485_RS02110	COG1741	Belongs to the pirin family
EML485_RS02115	COG1722	exodeoxyribonuclease VII activity
EML485_RS02120	COG0123	including yeast histone deacetylase and acetoin utilization protein
EML485_RS02125	COG1268	BioY protein
EML485_RS02130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EML485_RS02135	COG1122	ATPase activity
EML485_RS02140	COG3214	Protein conserved in bacteria
EML485_RS02145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EML485_RS02145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EML485_RS02150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EML485_RS02170	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EML485_RS02185	COG0259	pyridoxamine-phosphate oxidase activity
EML485_RS02200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EML485_RS02210	COG0312	modulator of DNA gyrase
EML485_RS02225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EML485_RS02230	COG0109	protoheme IX farnesyltransferase activity
EML485_RS02235	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EML485_RS02250	COG3346	SURF1 family
EML485_RS02255	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EML485_RS02260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EML485_RS02265	COG0328	RNA-DNA hybrid ribonuclease activity
EML485_RS02280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EML485_RS02280	COG0678	peroxiredoxin activity
EML485_RS02290	COG1678	Uncharacterized ACR, COG1678
EML485_RS02310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EML485_RS02315	COG0612	Peptidase, M16
EML485_RS02330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EML485_RS02335	COG1802	Transcriptional regulator
EML485_RS02350	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EML485_RS02365	COG1194	a g-specific adenine glycosylase
EML485_RS02375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EML485_RS02380	COG1196	nuclear chromosome segregation
EML485_RS02385	COG2514	catechol 2,3-dioxygenase activity
EML485_RS02390	COG0574	Belongs to the PEP-utilizing enzyme family
EML485_RS02390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EML485_RS02405	COG1823	symporter activity
EML485_RS02435	COG0579	oxidoreductase
EML485_RS02450	COG2895	sulfate adenylyltransferase (ATP) activity
EML485_RS02455	COG0175	sulfate reduction
EML485_RS02460	COG0175	sulfate reduction
EML485_RS02465	COG1959	2 iron, 2 sulfur cluster binding
EML485_RS02470	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EML485_RS02475	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EML485_RS02480	COG4208	sulfate ABC transporter
EML485_RS02485	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EML485_RS02495	COG2203	Gaf domain
EML485_RS02495	COG2200	EAL domain
EML485_RS02495	COG2199	diguanylate cyclase activity
EML485_RS02505	COG1309	transcriptional regulator
EML485_RS02510	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS02515	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EML485_RS02560	COG0477	Major facilitator Superfamily
EML485_RS02570	COG1793	dna ligase
EML485_RS02570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EML485_RS02590	COG1376	ErfK ybiS ycfS ynhG family protein
EML485_RS02595	COG1376	ErfK ybiS ycfS ynhG family protein
EML485_RS02600	COG1846	Transcriptional regulator
EML485_RS02605	COG1764	response to oxidative stress
EML485_RS02620	COG0488	(ABC) transporter
EML485_RS02655	COG4221	oxidoreductase activity
EML485_RS02670	COG0433	COG0433 Predicted ATPase
EML485_RS02680	COG1733	regulation of RNA biosynthetic process
EML485_RS02685	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EML485_RS02700	COG0656	L-ascorbic acid biosynthetic process
EML485_RS02705	COG2378	regulation of single-species biofilm formation
EML485_RS02715	COG4106	trans-aconitate 2-methyltransferase activity
EML485_RS02720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EML485_RS02725	COG0840	transmembrane signaling receptor activity
EML485_RS02730	COG0583	DNA-binding transcription factor activity
EML485_RS02745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EML485_RS02755	COG2378	regulation of single-species biofilm formation
EML485_RS02765	COG3909	cytochrome
EML485_RS02770	COG2010	Cytochrome c
EML485_RS02800	COG0789	Transcriptional regulator
EML485_RS02825	COG4175	Glycine betaine
EML485_RS02825	COG0517	IMP dehydrogenase activity
EML485_RS02830	COG4176	ABC-type proline glycine betaine transport system permease component
EML485_RS02855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML485_RS02865	COG2169	Transcriptional regulator
EML485_RS02865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EML485_RS02875	COG2514	catechol 2,3-dioxygenase activity
EML485_RS02895	COG1272	protein, Hemolysin III
EML485_RS02905	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EML485_RS02910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EML485_RS02910	COG2111	Na H antiporter
EML485_RS02915	COG2111	Na H antiporter
EML485_RS02920	COG1006	Multisubunit Na H antiporter MnhC subunit
EML485_RS02925	COG0651	ATP synthesis coupled electron transport
EML485_RS02930	COG1863	multisubunit Na H antiporter MnhE subunit
EML485_RS02935	COG2212	antiporter activity
EML485_RS02940	COG1320	monovalent cation:proton antiporter activity
EML485_RS02945	COG4957	zinc ion binding
EML485_RS02960	COG2166	iron-sulfur cluster assembly
EML485_RS02970	COG2205	protein histidine kinase activity
EML485_RS03025	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EML485_RS03030	COG2983	Belongs to the UPF0260 family
EML485_RS03040	COG3041	Addiction module toxin RelE StbE family
EML485_RS03045	COG3077	Addiction module antitoxin, RelB DinJ family
EML485_RS03075	COG2337	Toxic component of a toxin-antitoxin (TA) module
EML485_RS03085	COG2814	Major facilitator Superfamily
EML485_RS03095	COG1621	beta-fructofuranosidase activity
EML485_RS03100	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EML485_RS03150	COG4695	Portal protein
EML485_RS03265	COG4235	cytochrome complex assembly
EML485_RS03270	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EML485_RS03275	COG1138	Cytochrome C-type biogenesis protein
EML485_RS03280	COG3088	subunit of a heme lyase
EML485_RS03285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EML485_RS03295	COG2205	protein histidine kinase activity
EML485_RS03300	COG3713	MltA-interacting MipA family protein
EML485_RS03305	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EML485_RS03310	COG2202	Pas domain
EML485_RS03310	COG2205	protein histidine kinase activity
EML485_RS03320	COG0308	aminopeptidase N
EML485_RS03325	COG0697	spore germination
EML485_RS03340	COG0443	Heat shock 70 kDa protein
EML485_RS03380	COG0604	alcohol dehydrogenase
EML485_RS03385	COG1733	regulation of RNA biosynthetic process
EML485_RS03390	COG1968	undecaprenyl-diphosphatase activity
EML485_RS03395	COG2239	Acts as a magnesium transporter
EML485_RS03400	COG2814	Major facilitator Superfamily
EML485_RS03430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EML485_RS03460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EML485_RS03510	COG0741	lytic transglycosylase activity
EML485_RS03515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML485_RS03520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EML485_RS03525	COG0840	transmembrane signaling receptor activity
EML485_RS03535	COG1758	RNA polymerase activity
EML485_RS03555	COG0736	holo-[acyl-carrier-protein] synthase activity
EML485_RS03560	COG0681	Belongs to the peptidase S26 family
EML485_RS03565	COG0571	ribonuclease III activity
EML485_RS03570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EML485_RS03575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EML485_RS03580	COG0784	Response regulator, receiver
EML485_RS03585	COG1381	Involved in DNA repair and RecF pathway recombination
EML485_RS03595	COG2226	methyltransferase
EML485_RS03605	COG1418	mRNA catabolic process
EML485_RS03615	COG0346	lactoylglutathione lyase activity
EML485_RS03630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML485_RS03635	COG3443	Belongs to the bacterial solute-binding protein 9 family
EML485_RS03640	COG0668	transmembrane transport
EML485_RS03650	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EML485_RS03675	COG1051	belongs to the nudix hydrolase family
EML485_RS03680	COG1742	UPF0060 membrane protein
EML485_RS03695	COG1183	phosphatidylcholine synthase activity
EML485_RS03700	COG0688	phosphatidylethanolamine metabolic process
EML485_RS03705	COG5265	(ABC) transporter
EML485_RS03710	COG1652	LysM domain
EML485_RS03745	COG2852	Protein conserved in bacteria
EML485_RS03750	COG0215	cysteine-tRNA ligase activity
EML485_RS03755	COG4221	oxidoreductase activity
EML485_RS03760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EML485_RS03765	COG1286	toxin biosynthetic process
EML485_RS03785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EML485_RS03795	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EML485_RS03805	COG0305	Participates in initiation and elongation during chromosome replication
EML485_RS03825	COG0359	binds to the 23S rRNA
EML485_RS03835	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EML485_RS03840	COG0360	Binds together with S18 to 16S ribosomal RNA
EML485_RS03845	COG0667	Aldo Keto reductase
EML485_RS03850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EML485_RS03860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EML485_RS03865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EML485_RS03870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EML485_RS03875	COG1561	YicC-like family, N-terminal region
EML485_RS03880	COG0194	GDP metabolic process
EML485_RS03885	COG0400	carboxylic ester hydrolase activity
EML485_RS03890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EML485_RS03895	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EML485_RS03905	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EML485_RS03920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EML485_RS03940	COG5001	Diguanylate cyclase
EML485_RS03940	COG3300	MHYT domain
EML485_RS03945	COG4191	Histidine kinase
EML485_RS03960	COG0488	(ABC) transporter
EML485_RS03965	COG3706	GGDEF domain
EML485_RS03975	COG0105	UTP biosynthetic process
EML485_RS03995	COG0314	molybdopterin synthase activity
EML485_RS04000	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EML485_RS04005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EML485_RS04010	COG0322	excinuclease ABC activity
EML485_RS04015	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS04025	COG0625	glutathione transferase activity
EML485_RS04040	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EML485_RS04045	COG0243	molybdopterin cofactor binding
EML485_RS04060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EML485_RS04065	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EML485_RS04070	COG0628	permease
EML485_RS04080	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EML485_RS04085	COG0248	Ppx GppA phosphatase
EML485_RS04110	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EML485_RS04120	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EML485_RS04125	COG0477	Major facilitator Superfamily
EML485_RS04130	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EML485_RS04140	COG4452	Inner membrane protein CreD
EML485_RS04145	COG0659	secondary active sulfate transmembrane transporter activity
EML485_RS04155	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EML485_RS04160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EML485_RS04170	COG0113	porphobilinogen synthase activity
EML485_RS04190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EML485_RS04195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EML485_RS04200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EML485_RS04200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EML485_RS04210	COG1280	lysine exporter protein (LysE YggA)
EML485_RS04215	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EML485_RS04220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EML485_RS04225	COG2814	Major facilitator Superfamily
EML485_RS04230	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EML485_RS04250	COG0416	fatty acid biosynthetic process
EML485_RS04255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EML485_RS04260	COG0776	regulation of translation
EML485_RS04355	COG0601	transmembrane transport
EML485_RS04360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS04365	COG0444	Belongs to the ABC transporter superfamily
EML485_RS04385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EML485_RS04390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EML485_RS04405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EML485_RS04410	COG0583	DNA-binding transcription factor activity
EML485_RS04415	COG0737	Belongs to the 5'-nucleotidase family
EML485_RS04440	COG2897	thiosulfate sulfurtransferase activity
EML485_RS04455	COG0415	Belongs to the DNA photolyase family
EML485_RS04465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EML485_RS04495	COG3932	Exopolysaccharide synthesis, ExoD
EML485_RS04550	COG0297	glycogen (starch) synthase activity
EML485_RS04575	COG1612	heme a metabolic process
EML485_RS04585	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EML485_RS04590	COG0010	Belongs to the arginase family
EML485_RS04595	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EML485_RS04600	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EML485_RS04610	COG1832	CoA-binding protein
EML485_RS04635	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS04640	COG2124	cytochrome p450
EML485_RS04645	COG2199	diguanylate cyclase activity
EML485_RS04650	COG0740	serine-type endopeptidase activity
EML485_RS04655	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EML485_RS04660	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EML485_RS04690	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EML485_RS04695	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EML485_RS04700	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EML485_RS04710	COG0649	NAD binding
EML485_RS04720	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EML485_RS04725	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EML485_RS04735	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EML485_RS04740	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EML485_RS04750	COG0713	ATP synthesis coupled electron transport
EML485_RS04765	COG1007	ATP synthesis coupled electron transport
EML485_RS04785	COG0442	prolyl-tRNA aminoacylation
EML485_RS04795	COG1136	(ABC) transporter
EML485_RS04810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EML485_RS04820	COG0784	Response regulator, receiver
EML485_RS04830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EML485_RS04835	COG0477	Major facilitator Superfamily
EML485_RS04850	COG0557	exoribonuclease II activity
EML485_RS04855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EML485_RS04865	COG0758	DNA mediated transformation
EML485_RS04870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EML485_RS04880	COG0540	Belongs to the ATCase OTCase family
EML485_RS04890	COG1960	acyl-CoA dehydrogenase activity
EML485_RS04895	COG0456	acetyltransferase
EML485_RS04925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EML485_RS04930	COG2824	Alkylphosphonate utilization operon protein PhnA
EML485_RS04935	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EML485_RS04940	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EML485_RS04945	COG0154	amidase activity
EML485_RS04950	COG0456	acetyltransferase
EML485_RS04955	COG3811	Belongs to the UPF0386 family
EML485_RS04970	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EML485_RS04980	COG0456	acetyltransferase
EML485_RS04995	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EML485_RS05000	COG0439	Biotin carboxylase
EML485_RS05005	COG0511	ligase activity, forming carbon-carbon bonds
EML485_RS05010	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EML485_RS05020	COG0436	Aminotransferase
EML485_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS05045	COG1530	ribonuclease E activity
EML485_RS05060	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EML485_RS05080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EML485_RS05085	COG0384	phenazine biosynthesis protein PhzF
EML485_RS05105	COG0633	Ferredoxin
EML485_RS05115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EML485_RS05120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EML485_RS05125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EML485_RS05135	COG3768	UPF0283 membrane protein
EML485_RS05140	COG3106	COG3106 Predicted ATPase
EML485_RS05170	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EML485_RS05200	COG0537	adenosine 5'-monophosphoramidase activity
EML485_RS05225	COG0052	Belongs to the universal ribosomal protein uS2 family
EML485_RS05230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EML485_RS05235	COG0528	UMP kinase activity
EML485_RS05240	COG0233	cytoplasmic translational termination
EML485_RS05245	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EML485_RS05255	COG0750	zinc metalloprotease
EML485_RS05260	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EML485_RS05265	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EML485_RS05270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EML485_RS05275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EML485_RS05280	COG3494	Protein of unknown function (DUF1009)
EML485_RS05285	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EML485_RS05290	COG2186	Transcriptional regulator
EML485_RS05300	COG0765	amino acid transport
EML485_RS05305	COG0765	amino acid transport
EML485_RS05315	COG0372	Belongs to the citrate synthase family
EML485_RS05330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EML485_RS05335	COG4598	ABC transporter
EML485_RS05340	COG0765	amino acid transport
EML485_RS05345	COG0765	amino acid transport
EML485_RS05350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS05355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EML485_RS05365	COG0395	ABC-type sugar transport system, permease component
EML485_RS05375	COG2182	Extracellular solute-binding protein
EML485_RS05385	COG4948	Mandelate Racemase Muconate Lactonizing
EML485_RS05390	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS05395	COG1063	alcohol dehydrogenase
EML485_RS05400	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EML485_RS05420	COG0683	leucine binding
EML485_RS05425	COG1960	acyl-CoA dehydrogenase activity
EML485_RS05440	COG1024	Enoyl-CoA hydratase
EML485_RS05455	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML485_RS05475	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EML485_RS05480	COG0148	phosphopyruvate hydratase activity
EML485_RS05490	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EML485_RS05495	COG0508	dehydrogenase complex catalyzes the overall conversion of
EML485_RS05495	COG0022	dehydrogenase e1 component
EML485_RS05505	COG0508	dehydrogenase complex catalyzes the overall conversion of
EML485_RS05515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EML485_RS05525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EML485_RS05530	COG0697	spore germination
EML485_RS05550	COG2867	negative regulation of translational initiation
EML485_RS05560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EML485_RS05560	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EML485_RS05570	COG3852	Histidine kinase
EML485_RS05575	COG2204	response regulator
EML485_RS05580	COG5000	phosphorelay sensor kinase activity
EML485_RS05585	COG2204	response regulator
EML485_RS05590	COG0569	domain protein
EML485_RS05595	COG1923	regulation of RNA biosynthetic process
EML485_RS05600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EML485_RS05605	COG3956	TIGRFAM MazG family protein
EML485_RS05615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EML485_RS05615	COG1648	precorrin-2 dehydrogenase activity
EML485_RS05630	COG0275	rRNA processing
EML485_RS05655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EML485_RS05655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EML485_RS05660	COG0509	glycine decarboxylation via glycine cleavage system
EML485_RS05665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML485_RS05690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EML485_RS05695	COG0564	pseudouridine synthase activity
EML485_RS05715	COG0251	oxidation-reduction process
EML485_RS05720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EML485_RS05730	COG1671	Belongs to the UPF0178 family
EML485_RS05740	COG0450	alkyl hydroperoxide reductase
EML485_RS05780	COG2826	transposase and inactivated derivatives, IS30 family
EML485_RS05785	COG0431	NADPH-dependent FMN reductase
EML485_RS05795	COG0798	PFAM Bile acid sodium symporter
EML485_RS05815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EML485_RS05815	COG0321	lipoyl(octanoyl) transferase activity
EML485_RS05820	COG0084	hydrolase, TatD family'
EML485_RS05825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EML485_RS05835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EML485_RS05890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EML485_RS05895	COG2095	MarC family integral membrane protein
EML485_RS05900	COG0517	IMP dehydrogenase activity
EML485_RS05900	COG0617	tRNA 3'-terminal CCA addition
EML485_RS05900	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EML485_RS05910	COG3609	addiction module antidote protein, CC2985 family
EML485_RS05915	COG0629	single-stranded DNA binding
EML485_RS05920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EML485_RS05930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EML485_RS05935	COG0179	Fumarylacetoacetate (FAA) hydrolase
EML485_RS05950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EML485_RS05955	COG1121	(ABC) transporter
EML485_RS05975	COG0667	Aldo Keto reductase
EML485_RS05985	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EML485_RS06055	COG0668	transmembrane transport
EML485_RS06080	COG2239	Acts as a magnesium transporter
EML485_RS06085	COG0243	molybdopterin cofactor binding
EML485_RS06095	COG0242	peptide deformylase activity
EML485_RS06120	COG0321	lipoyl(octanoyl) transferase activity
EML485_RS06125	COG1064	alcohol dehydrogenase
EML485_RS06155	COG1862	Preprotein translocase
EML485_RS06180	COG2124	cytochrome p450
EML485_RS06195	COG0596	Alpha beta hydrolase
EML485_RS06210	COG0626	cystathionine gamma-synthase activity
EML485_RS06215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS06220	COG4597	amino acid ABC transporter
EML485_RS06225	COG0765	amino acid transport
EML485_RS06230	COG1126	abc transporter atp-binding protein
EML485_RS06245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EML485_RS06260	COG0436	Aminotransferase
EML485_RS06290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EML485_RS06300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EML485_RS06305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EML485_RS06310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EML485_RS06325	COG3243	poly(R)-hydroxyalkanoic acid synthase
EML485_RS06330	COG1489	DNA binding
EML485_RS06335	COG0024	Methionine aminopeptidase
EML485_RS06340	COG2003	Belongs to the UPF0758 family
EML485_RS06355	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EML485_RS06370	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EML485_RS06375	COG0546	phosphoglycolate phosphatase activity
EML485_RS06385	COG0114	fumarate hydratase activity
EML485_RS06395	COG0504	CTP synthase activity
EML485_RS06405	COG0149	triose-phosphate isomerase activity
EML485_RS06415	COG0187	DNA topoisomerase II activity
EML485_RS06425	COG1309	transcriptional regulator
EML485_RS06430	COG2226	methyltransferase
EML485_RS06440	COG0740	serine-type endopeptidase activity
EML485_RS06450	COG0640	Transcriptional regulator
EML485_RS06455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EML485_RS06460	COG0745	RESPONSE REGULATOR receiver
EML485_RS06470	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EML485_RS06470	COG3264	Mechanosensitive ion channel
EML485_RS06530	COG1127	ABC transporter
EML485_RS06535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EML485_RS06540	COG4948	Mandelate Racemase Muconate Lactonizing
EML485_RS06555	COG0280	phosphate acetyltransferase
EML485_RS06555	COG0281	malic enzyme
EML485_RS06565	COG0778	Nitroreductase
EML485_RS06570	COG0823	Involved in the tonB-independent uptake of proteins
EML485_RS06580	COG1368	sulfuric ester hydrolase activity
EML485_RS06605	COG0544	peptidyl-prolyl cis-trans isomerase activity
EML485_RS06625	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EML485_RS06630	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EML485_RS06670	COG0343	queuine tRNA-ribosyltransferase activity
EML485_RS06675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EML485_RS06690	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EML485_RS06705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EML485_RS06710	COG0134	indole-3-glycerol-phosphate synthase activity
EML485_RS06715	COG0315	cyclic pyranopterin monophosphate synthase activity
EML485_RS06720	COG0303	'Molybdopterin
EML485_RS06725	COG3706	GGDEF domain
EML485_RS06735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EML485_RS06735	COG0475	glutathione-regulated potassium exporter activity
EML485_RS06745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EML485_RS06750	COG0697	spore germination
EML485_RS06755	COG2814	Major facilitator Superfamily
EML485_RS06760	COG0746	molybdenum cofactor guanylyltransferase activity
EML485_RS06765	COG1763	Mo-molybdopterin cofactor biosynthetic process
EML485_RS06770	COG0739	heme binding
EML485_RS06775	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EML485_RS06780	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EML485_RS06785	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EML485_RS06790	COG0805	protein transport
EML485_RS06795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EML485_RS06800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EML485_RS06805	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EML485_RS06810	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EML485_RS06815	COG1472	Belongs to the glycosyl hydrolase 3 family
EML485_RS06825	COG0018	arginyl-trna synthetase
EML485_RS06830	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EML485_RS06835	COG0316	Belongs to the HesB IscA family
EML485_RS06845	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EML485_RS06860	COG0525	valine-tRNA ligase activity
EML485_RS06870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EML485_RS06900	COG0655	NAD(P)H dehydrogenase (quinone) activity
EML485_RS06905	COG1546	Belongs to the CinA family
EML485_RS06905	COG1058	Belongs to the CinA family
EML485_RS06910	COG0589	response to stress
EML485_RS06915	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EML485_RS06920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EML485_RS06935	COG1914	H( )-stimulated, divalent metal cation uptake system
EML485_RS06945	COG1132	(ABC) transporter
EML485_RS06950	COG0628	permease
EML485_RS06970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EML485_RS06985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EML485_RS06995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EML485_RS07005	COG0302	gtp cyclohydrolase
EML485_RS07010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EML485_RS07015	COG1752	Esterase of the alpha-beta hydrolase superfamily
EML485_RS07020	COG0516	GMP reductase activity
EML485_RS07020	COG0517	IMP dehydrogenase activity
EML485_RS07050	COG1760	l-serine dehydratase
EML485_RS07085	COG0583	DNA-binding transcription factor activity
EML485_RS07095	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EML485_RS07095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EML485_RS07100	COG0347	Belongs to the P(II) protein family
EML485_RS07105	COG0174	glutamine synthetase
EML485_RS07135	COG0697	spore germination
EML485_RS07145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EML485_RS07155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EML485_RS07165	COG3668	Plasmid stabilization system
EML485_RS07170	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EML485_RS07185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EML485_RS07190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EML485_RS07195	COG2186	Transcriptional regulator
EML485_RS07205	COG1079	Belongs to the binding-protein-dependent transport system permease family
EML485_RS07210	COG4603	Belongs to the binding-protein-dependent transport system permease family
EML485_RS07215	COG3845	ABC transporter
EML485_RS07220	COG1183	phosphatidylcholine synthase activity
EML485_RS07225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EML485_RS07230	COG0679	Auxin Efflux Carrier
EML485_RS07235	COG0785	Cytochrome C biogenesis protein
EML485_RS07265	COG1278	Cold shock
EML485_RS07315	COG2267	carboxylic ester hydrolase activity
EML485_RS07330	COG1136	(ABC) transporter
EML485_RS07330	COG0577	efflux transmembrane transporter activity
EML485_RS07335	COG1136	(ABC) transporter
EML485_RS07335	COG0577	efflux transmembrane transporter activity
EML485_RS07350	COG2151	metal-sulfur cluster biosynthetic enzyme
EML485_RS07355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EML485_RS07360	COG0719	Fe-S assembly protein
EML485_RS07365	COG0396	ATPase activity
EML485_RS07370	COG0719	Fe-S assembly protein
EML485_RS07375	COG1104	cysteine desulfurase activity
EML485_RS07380	COG2945	thiolester hydrolase activity
EML485_RS07385	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EML485_RS07390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EML485_RS07400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EML485_RS07405	COG2833	Protein of unknown function (DUF455)
EML485_RS07410	COG0739	heme binding
EML485_RS07415	COG0513	Belongs to the DEAD box helicase family
EML485_RS07445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EML485_RS07455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EML485_RS07460	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EML485_RS07465	COG0047	phosphoribosylformylglycinamidine synthase activity
EML485_RS07480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EML485_RS07490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EML485_RS07510	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EML485_RS07515	COG2814	Major facilitator Superfamily
EML485_RS07520	COG0483	inositol monophosphate 1-phosphatase activity
EML485_RS07525	COG0483	inositol monophosphate 1-phosphatase activity
EML485_RS07530	COG0037	tRNA processing
EML485_RS07535	COG2066	Belongs to the glutaminase family
EML485_RS07540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EML485_RS07545	COG0861	Integral membrane protein TerC family
EML485_RS07560	COG1280	lysine exporter protein (LysE YggA)
EML485_RS07570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EML485_RS07575	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EML485_RS07585	COG0538	isocitrate dehydrogenase activity
EML485_RS07600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EML485_RS07605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EML485_RS07610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML485_RS07615	COG2313	pseudouridylate synthase activity
EML485_RS07625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS07630	COG4215	(ABC) transporter
EML485_RS07640	COG5425	PFAM Usg family protein
EML485_RS07650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML485_RS07655	COG1522	sequence-specific DNA binding
EML485_RS07660	COG1573	uracil-dna glycosylase
EML485_RS07670	COG2202	Pas domain
EML485_RS07670	COG2205	protein histidine kinase activity
EML485_RS07680	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EML485_RS07685	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EML485_RS07700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EML485_RS07705	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS07710	COG1129	ABC transporter
EML485_RS07720	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS07725	COG3959	Transketolase, thiamine diphosphate binding domain
EML485_RS07730	COG3958	Transketolase
EML485_RS07735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EML485_RS07740	COG2390	Transcriptional regulator
EML485_RS07750	COG0842	Transport permease protein
EML485_RS07755	COG1131	(ABC) transporter
EML485_RS07780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EML485_RS07785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EML485_RS07800	COG0129	dihydroxy-acid dehydratase activity
EML485_RS07805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EML485_RS07810	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EML485_RS07820	COG3739	integral membrane protein
EML485_RS07825	COG0203	ribosomal protein L17
EML485_RS07830	COG0202	RNA polymerase activity
EML485_RS07835	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EML485_RS07840	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EML485_RS07845	COG0563	adenylate kinase activity
EML485_RS07850	COG0201	protein transport
EML485_RS07855	COG0200	Binds to the 23S rRNA
EML485_RS07860	COG1841	ribosomal large subunit assembly
EML485_RS07865	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EML485_RS07870	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EML485_RS07875	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EML485_RS07880	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EML485_RS07885	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EML485_RS07890	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EML485_RS07895	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EML485_RS07900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EML485_RS07905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EML485_RS07910	COG0255	Belongs to the universal ribosomal protein uL29 family
EML485_RS07915	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EML485_RS07920	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EML485_RS07925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EML485_RS07930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EML485_RS07935	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EML485_RS07940	COG0089	rRNA binding
EML485_RS07945	COG0088	Forms part of the polypeptide exit tunnel
EML485_RS07950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EML485_RS07955	COG0051	transcription antitermination factor activity, RNA binding
EML485_RS07960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EML485_RS07965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EML485_RS07970	COG0049	tRNA binding
EML485_RS07975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EML485_RS07995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EML485_RS08000	COG0085	RNA polymerase activity
EML485_RS08005	COG0222	ribosome binding
EML485_RS08010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EML485_RS08015	COG0081	regulation of translation
EML485_RS08020	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EML485_RS08030	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EML485_RS08040	COG1086	Polysaccharide biosynthesis protein
EML485_RS08045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EML485_RS08050	COG0861	Integral membrane protein TerC family
EML485_RS08055	COG3895	Periplasmic Protein
EML485_RS08075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EML485_RS08095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EML485_RS08130	COG2205	protein histidine kinase activity
EML485_RS08130	COG2198	Histidine kinase
EML485_RS08130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS08130	COG0784	Response regulator, receiver
EML485_RS08135	COG0784	Response regulator, receiver
EML485_RS08140	COG3920	Histidine kinase
EML485_RS08140	COG2202	Pas domain
EML485_RS08145	COG0784	Response regulator, receiver
EML485_RS08150	COG4251	negative regulation of phosphorylation
EML485_RS08165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EML485_RS08195	COG2910	NAD(P)H-binding
EML485_RS08200	COG1733	regulation of RNA biosynthetic process
EML485_RS08205	COG0556	nucleotide-excision repair
EML485_RS08210	COG2382	esterase
EML485_RS08230	COG0484	heat shock protein binding
EML485_RS08245	COG3706	GGDEF domain
EML485_RS08255	COG3842	ATPase activity
EML485_RS08265	COG1840	ABC-type Fe3 transport system, periplasmic component
EML485_RS08270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EML485_RS08280	COG4115	mRNA cleavage
EML485_RS08290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EML485_RS08300	COG2207	Transcriptional regulator
EML485_RS08305	COG1064	alcohol dehydrogenase
EML485_RS08310	COG1252	NADH dehydrogenase
EML485_RS08315	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EML485_RS08320	COG2197	response regulator
EML485_RS08325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EML485_RS08355	COG0656	L-ascorbic acid biosynthetic process
EML485_RS08370	COG0440	acetolactate synthase activity
EML485_RS08375	COG0028	Belongs to the TPP enzyme family
EML485_RS08385	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EML485_RS08390	COG3830	Belongs to the UPF0237 family
EML485_RS08390	COG0560	Phosphoserine phosphatase
EML485_RS08400	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS08410	COG0330	HflC and HflK could
EML485_RS08415	COG0330	HflC and HflK could
EML485_RS08425	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EML485_RS08460	COG0277	FAD linked oxidase domain protein
EML485_RS08465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EML485_RS08520	COG1335	isochorismatase
EML485_RS08540	COG0006	proline dipeptidase activity
EML485_RS08550	COG2264	protein methyltransferase activity
EML485_RS08555	COG1999	signal sequence binding
EML485_RS08565	COG0835	chemotaxis
EML485_RS08575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EML485_RS08580	COG0583	DNA-binding transcription factor activity
EML485_RS08590	COG1247	-acetyltransferase
EML485_RS08600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EML485_RS08605	COG0497	DNA recombination
EML485_RS08610	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EML485_RS08620	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EML485_RS08625	COG0849	cell division
EML485_RS08630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EML485_RS08635	COG1181	Belongs to the D-alanine--D-alanine ligase family
EML485_RS08640	COG0477	Major facilitator Superfamily
EML485_RS08645	COG5001	Diguanylate cyclase
EML485_RS08645	COG3300	MHYT domain
EML485_RS08650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EML485_RS08655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EML485_RS08660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EML485_RS08670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EML485_RS08675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EML485_RS08685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EML485_RS08700	COG0275	rRNA processing
EML485_RS08705	COG2001	Belongs to the MraZ family
EML485_RS08710	COG3766	membrane
EML485_RS08755	COG3023	N-Acetylmuramoyl-L-alanine amidase
EML485_RS08785	COG4106	trans-aconitate 2-methyltransferase activity
EML485_RS08805	COG2226	methyltransferase
EML485_RS08815	COG2267	carboxylic ester hydrolase activity
EML485_RS08820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EML485_RS08835	COG0251	oxidation-reduction process
EML485_RS08850	COG1376	ErfK ybiS ycfS ynhG family protein
EML485_RS08855	COG2814	Major facilitator Superfamily
EML485_RS08880	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS08895	COG0174	glutamine synthetase
EML485_RS08900	COG0531	amino acid
EML485_RS08910	COG1737	Transcriptional regulator
EML485_RS08930	COG3842	ATPase activity
EML485_RS08990	COG2968	Membrane
EML485_RS09000	COG0432	Pfam Uncharacterised protein family UPF0047
EML485_RS09015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EML485_RS09020	COG0358	DNA primase activity
EML485_RS09030	COG0505	Belongs to the CarA family
EML485_RS09045	COG0534	Mate efflux family protein
EML485_RS09060	COG2321	neutral zinc metallopeptidase
EML485_RS09075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EML485_RS09085	COG3706	GGDEF domain
EML485_RS09100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EML485_RS09110	COG1522	sequence-specific DNA binding
EML485_RS09115	COG0492	ferredoxin-NADP+ reductase activity
EML485_RS09120	COG0583	DNA-binding transcription factor activity
EML485_RS09130	COG1902	pentaerythritol trinitrate reductase activity
EML485_RS09155	COG0387	Pfam Sodium calcium exchanger
EML485_RS09160	COG0436	Aminotransferase
EML485_RS09165	COG2199	diguanylate cyclase activity
EML485_RS09165	COG2200	EAL domain
EML485_RS09180	COG1278	Cold shock
EML485_RS09185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EML485_RS09195	COG1846	Transcriptional regulator
EML485_RS09200	COG0745	RESPONSE REGULATOR receiver
EML485_RS09205	COG2205	protein histidine kinase activity
EML485_RS09210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EML485_RS09230	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EML485_RS09240	COG1496	oxidoreductase activity
EML485_RS09255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EML485_RS09265	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EML485_RS09280	COG0840	transmembrane signaling receptor activity
EML485_RS09285	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS09290	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EML485_RS09295	COG3300	MHYT domain
EML485_RS09295	COG5001	Diguanylate cyclase
EML485_RS09300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EML485_RS09305	COG5001	Diguanylate cyclase
EML485_RS09315	COG0193	aminoacyl-tRNA hydrolase activity
EML485_RS09325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EML485_RS09345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EML485_RS09350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EML485_RS09350	COG2857	Cytochrome c1
EML485_RS09370	COG1132	(ABC) transporter
EML485_RS09375	COG1132	(ABC) transporter
EML485_RS09380	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EML485_RS09385	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EML485_RS09400	COG0408	coproporphyrinogen oxidase activity
EML485_RS09415	COG0617	tRNA 3'-terminal CCA addition
EML485_RS09420	COG0494	nUDIX hydrolase
EML485_RS09430	COG0714	Associated with various cellular activities
EML485_RS09450	COG0454	-acetyltransferase
EML485_RS09455	COG0477	Major facilitator Superfamily
EML485_RS09465	COG0435	Glutathione S-transferase
EML485_RS09470	COG0494	nUDIX hydrolase
EML485_RS09480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EML485_RS09485	COG3135	benzoate transporter
EML485_RS09500	COG1595	DNA-templated transcription, initiation
EML485_RS09510	COG0740	serine-type endopeptidase activity
EML485_RS09525	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EML485_RS09530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EML485_RS09555	COG4175	Glycine betaine
EML485_RS09570	COG1435	thymidine kinase activity
EML485_RS09590	COG2862	Uncharacterized protein family, UPF0114
EML485_RS09605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EML485_RS09605	COG0512	Glutamine amidotransferase of anthranilate synthase
EML485_RS09620	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EML485_RS09635	COG0366	Alpha amylase catalytic
EML485_RS09640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML485_RS09660	COG1160	GTP binding
EML485_RS09680	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EML485_RS09690	COG0024	Methionine aminopeptidase
EML485_RS09700	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS09710	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EML485_RS09720	COG0583	DNA-binding transcription factor activity
EML485_RS09735	COG0402	S-adenosylhomocysteine deaminase activity
EML485_RS09750	COG1304	FMN binding
EML485_RS09760	COG1309	transcriptional regulator
EML485_RS09765	COG1686	Belongs to the peptidase S11 family
EML485_RS09775	COG2351	hydroxyisourate hydrolase activity
EML485_RS09780	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EML485_RS09805	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EML485_RS09815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS09815	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EML485_RS09825	COG0513	Belongs to the DEAD box helicase family
EML485_RS09830	COG0697	spore germination
EML485_RS09835	COG2259	Doxx family
EML485_RS09840	COG1376	ErfK ybiS ycfS ynhG family protein
EML485_RS09850	COG2308	Evidence 4 Homologs of previously reported genes of
EML485_RS09860	COG1305	Transglutaminase-like
EML485_RS09865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EML485_RS09875	COG0456	acetyltransferase
EML485_RS09890	COG4214	carbohydrate transport
EML485_RS09895	COG1129	ABC transporter
EML485_RS09900	COG4213	ABC transporter substrate-binding protein
EML485_RS09935	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EML485_RS09945	COG0840	transmembrane signaling receptor activity
EML485_RS09950	COG2814	Major facilitator Superfamily
EML485_RS09955	COG0646	methionine synthase
EML485_RS09955	COG1410	methionine synthase
EML485_RS09965	COG4215	(ABC) transporter
EML485_RS09970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS09995	COG1215	transferase activity, transferring glycosyl groups
EML485_RS10025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EML485_RS10030	COG2346	COG2346, Truncated hemoglobins
EML485_RS10050	COG1309	transcriptional regulator
EML485_RS10065	COG0494	nUDIX hydrolase
EML485_RS10075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML485_RS10080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML485_RS10110	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EML485_RS10115	COG0830	nickel cation binding
EML485_RS10120	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EML485_RS10135	COG0804	urea catabolic process
EML485_RS10140	COG1442	glycosyl transferase family 8
EML485_RS10145	COG3755	Protein conserved in bacteria
EML485_RS10155	COG0832	Belongs to the urease beta subunit family
EML485_RS10160	COG3813	Protein conserved in bacteria
EML485_RS10165	COG0831	urea catabolic process
EML485_RS10170	COG0829	nickel cation binding
EML485_RS10195	COG0559	Belongs to the binding-protein-dependent transport system permease family
EML485_RS10210	COG0174	glutamine synthetase
EML485_RS10215	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS10220	COG0784	Response regulator, receiver
EML485_RS10220	COG5002	protein histidine kinase activity
EML485_RS10220	COG2198	Histidine kinase
EML485_RS10270	COG1218	3'(2'),5'-bisphosphate nucleotidase
EML485_RS10345	COG0564	pseudouridine synthase activity
EML485_RS10355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EML485_RS10365	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EML485_RS10390	COG0346	lactoylglutathione lyase activity
EML485_RS10400	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EML485_RS10410	COG2832	Protein of unknown function (DUF454)
EML485_RS10415	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EML485_RS10420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML485_RS10425	COG4558	Periplasmic binding protein
EML485_RS10435	COG3721	Heme iron utilization protein
EML485_RS10450	COG2205	protein histidine kinase activity
EML485_RS10490	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML485_RS10495	COG4605	iron ion homeostasis
EML485_RS10500	COG4604	ABC transporter, ATP-binding protein
EML485_RS10505	COG0783	Belongs to the Dps family
EML485_RS10520	COG0583	DNA-binding transcription factor activity
EML485_RS10525	COG0657	acetylesterase activity
EML485_RS10530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML485_RS10550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EML485_RS10555	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EML485_RS10560	COG0288	reversible hydration of carbon dioxide
EML485_RS10570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EML485_RS10585	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EML485_RS10590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EML485_RS10595	COG0778	Nitroreductase
EML485_RS10600	COG2267	carboxylic ester hydrolase activity
EML485_RS10605	COG0251	oxidation-reduction process
EML485_RS10610	COG1335	isochorismatase
EML485_RS10615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS10625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML485_RS10640	COG1175	transmembrane transport
EML485_RS10645	COG0395	ABC-type sugar transport system, permease component
EML485_RS10650	COG3842	ATPase activity
EML485_RS10655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML485_RS10665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EML485_RS10680	COG4608	Belongs to the ABC transporter superfamily
EML485_RS10685	COG0444	Belongs to the ABC transporter superfamily
EML485_RS10690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS10695	COG0601	transmembrane transport
EML485_RS10715	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EML485_RS10715	COG0392	lysyltransferase activity
EML485_RS10760	COG1960	acyl-CoA dehydrogenase activity
EML485_RS10790	COG0745	RESPONSE REGULATOR receiver
EML485_RS10800	COG0446	pyridine nucleotide-disulphide oxidoreductase
EML485_RS10800	COG1902	pentaerythritol trinitrate reductase activity
EML485_RS10835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EML485_RS10845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML485_RS10850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EML485_RS10860	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EML485_RS10870	COG1509	lysine 2,3-aminomutase activity
EML485_RS10885	COG0583	DNA-binding transcription factor activity
EML485_RS10890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS10895	COG0725	ABC transporter, periplasmic molybdate-binding protein
EML485_RS10900	COG4149	molybdate abc transporter
EML485_RS10905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EML485_RS10915	COG3191	aminopeptidase activity
EML485_RS10920	COG2022	thiamine diphosphate biosynthetic process
EML485_RS10935	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EML485_RS10940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EML485_RS10950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EML485_RS10975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EML485_RS11000	COG0438	transferase activity, transferring glycosyl groups
EML485_RS11020	COG4166	transmembrane transport
EML485_RS11025	COG0601	transmembrane transport
EML485_RS11030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS11040	COG0438	transferase activity, transferring glycosyl groups
EML485_RS11045	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EML485_RS11050	COG3142	Participates in the control of copper homeostasis
EML485_RS11070	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS11075	COG1737	Transcriptional regulator
EML485_RS11085	COG3842	ATPase activity
EML485_RS11095	COG0395	ABC-type sugar transport system, permease component
EML485_RS11100	COG1175	transmembrane transport
EML485_RS11110	COG2188	Transcriptional regulator
EML485_RS11115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EML485_RS11120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EML485_RS11125	COG1940	carbohydrate kinase activity
EML485_RS11135	COG0671	phosphoesterase, PA-phosphatase related
EML485_RS11140	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EML485_RS11145	COG0156	8-amino-7-oxononanoate synthase activity
EML485_RS11155	COG0729	surface antigen
EML485_RS11165	COG0835	chemotaxis
EML485_RS11175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EML485_RS11180	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EML485_RS11185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EML485_RS11190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EML485_RS11195	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EML485_RS11200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EML485_RS11215	COG4974	Belongs to the 'phage' integrase family
EML485_RS11240	COG1280	lysine exporter protein (LysE YggA)
EML485_RS11250	COG0508	dehydrogenase complex catalyzes the overall conversion of
EML485_RS11260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EML485_RS11265	COG0045	succinate-CoA ligase (ADP-forming) activity
EML485_RS11270	COG0039	L-malate dehydrogenase activity
EML485_RS11275	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EML485_RS11310	COG2264	protein methyltransferase activity
EML485_RS11325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EML485_RS11330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EML485_RS11335	COG0181	hydroxymethylbilane synthase activity
EML485_RS11375	COG1872	DUF167
EML485_RS11380	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EML485_RS11390	COG1217	gtp-binding protein TYPA
EML485_RS11395	COG0339	signal peptide processing
EML485_RS11400	COG1846	Transcriptional regulator
EML485_RS11410	COG0137	argininosuccinate synthase activity
EML485_RS11420	COG1280	lysine exporter protein (LysE YggA)
EML485_RS11425	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EML485_RS11430	COG4120	Belongs to the binding-protein-dependent transport system permease family
EML485_RS11440	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EML485_RS11455	COG2154	pterin-4-alpha-carbinolamine dehydratase
EML485_RS11460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EML485_RS11465	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EML485_RS11475	COG4181	ATPase activity
EML485_RS11485	COG0670	Belongs to the BI1 family
EML485_RS11500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EML485_RS11505	COG4133	protoheme IX ABC transporter activity
EML485_RS11510	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EML485_RS11515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EML485_RS11540	COG2917	probably involved in intracellular septation
EML485_RS11545	COG0552	protein localization to endoplasmic reticulum
EML485_RS11550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EML485_RS11555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EML485_RS11565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EML485_RS11570	COG1605	Chorismate mutase
EML485_RS11570	COG0287	Prephenate dehydrogenase
EML485_RS11575	COG0228	four-way junction DNA binding
EML485_RS11580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EML485_RS11585	COG0336	Belongs to the RNA methyltransferase TrmD family
EML485_RS11595	COG0335	large ribosomal subunit rRNA binding
EML485_RS11600	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
EML485_RS11605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML485_RS11620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EML485_RS11630	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EML485_RS11650	COG0488	(ABC) transporter
EML485_RS11660	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EML485_RS11670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EML485_RS11675	COG0142	geranyltranstransferase activity
EML485_RS11680	COG2885	chlorophyll binding
EML485_RS11685	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EML485_RS11690	COG2223	nitrite transmembrane transporter activity
EML485_RS11695	COG1349	DNA-binding transcription factor activity
EML485_RS11700	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EML485_RS11705	COG2197	response regulator
EML485_RS11710	COG1132	(ABC) transporter
EML485_RS11720	COG3459	Glycosyltransferase 36 associated
EML485_RS11725	COG1473	amidohydrolase
EML485_RS11730	COG0579	oxidoreductase
EML485_RS11740	COG0129	dihydroxy-acid dehydratase activity
EML485_RS11745	COG2084	Dehydrogenase
EML485_RS11750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML485_RS11755	COG0277	FAD linked oxidase domain protein
EML485_RS11760	COG2186	Transcriptional regulator
EML485_RS11770	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EML485_RS11775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EML485_RS11780	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EML485_RS11785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EML485_RS11795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EML485_RS11800	COG0495	leucyl-tRNA aminoacylation
EML485_RS11815	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EML485_RS11830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EML485_RS11835	COG1946	Acyl-CoA thioesterase
EML485_RS11840	COG0347	Belongs to the P(II) protein family
EML485_RS11845	COG0004	ammonium transporteR
EML485_RS11850	COG1674	ftsk spoiiie
EML485_RS11855	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EML485_RS11870	COG0745	RESPONSE REGULATOR receiver
EML485_RS11880	COG1329	Transcriptional regulator
EML485_RS11885	COG2902	Dehydrogenase
EML485_RS11890	COG2270	Major facilitator Superfamily
EML485_RS11905	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS11920	COG0494	nUDIX hydrolase
EML485_RS11930	COG0793	Belongs to the peptidase S41A family
EML485_RS11940	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EML485_RS11945	COG0799	negative regulation of ribosome biogenesis
EML485_RS11950	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EML485_RS11955	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EML485_RS11960	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EML485_RS11965	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EML485_RS11980	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EML485_RS11985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EML485_RS12010	COG0066	3-isopropylmalate dehydratase activity
EML485_RS12015	COG0473	3-isopropylmalate dehydrogenase activity
EML485_RS12020	COG1858	cytochrome C peroxidase
EML485_RS12025	COG1797	cobyrinic acid a,c-diamide synthase activity
EML485_RS12030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EML485_RS12030	COG1648	precorrin-2 dehydrogenase activity
EML485_RS12035	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EML485_RS12100	COG1492	cobalamin metabolic process
EML485_RS12115	COG4948	Mandelate Racemase Muconate Lactonizing
EML485_RS12120	COG3254	rhamnose metabolic process
EML485_RS12125	COG0246	Mannitol dehydrogenase
EML485_RS12130	COG1063	alcohol dehydrogenase
EML485_RS12150	COG4214	carbohydrate transport
EML485_RS12155	COG1129	ABC transporter
EML485_RS12160	COG2186	Transcriptional regulator
EML485_RS12165	COG2721	sulfolactate sulfo-lyase activity
EML485_RS12170	COG0138	bifunctional purine biosynthesis protein purh
EML485_RS12180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EML485_RS12180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EML485_RS12185	COG0501	Belongs to the peptidase M48B family
EML485_RS12205	COG0357	Ribosomal RNA small subunit methyltransferase G
EML485_RS12210	COG0445	tRNA wobble uridine modification
EML485_RS12215	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EML485_RS12220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EML485_RS12225	COG1981	membrane
EML485_RS12230	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EML485_RS12235	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EML485_RS12240	COG0424	maF-like protein
EML485_RS12245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EML485_RS12250	COG0237	dephospho-CoA kinase activity
EML485_RS12260	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EML485_RS12265	COG3030	protein affecting phage T7 exclusion by the F plasmid
EML485_RS12275	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EML485_RS12300	COG0179	Fumarylacetoacetate (FAA) hydrolase
EML485_RS12315	COG0135	phosphoribosylanthranilate isomerase activity
EML485_RS12320	COG0133	tryptophan synthase activity
EML485_RS12325	COG0159	tryptophan synthase activity
EML485_RS12330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EML485_RS12355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EML485_RS12365	COG2205	protein histidine kinase activity
EML485_RS12370	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EML485_RS12375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EML485_RS12380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EML485_RS12380	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EML485_RS12385	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EML485_RS12390	COG0642	Histidine kinase
EML485_RS12395	COG0745	RESPONSE REGULATOR receiver
EML485_RS12400	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EML485_RS12410	COG1072	(Pantothenic acid kinase))
EML485_RS12415	COG0140	phosphoribosyl-ATP diphosphatase activity
EML485_RS12420	COG0107	imidazoleglycerol-phosphate synthase activity
EML485_RS12425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EML485_RS12430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EML485_RS12440	COG0131	Imidazoleglycerol-phosphate dehydratase
EML485_RS12445	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EML485_RS12450	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EML485_RS12460	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EML485_RS12475	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EML485_RS12485	COG1643	Atp-dependent helicase
EML485_RS12520	COG0514	ATP-dependent DNA helicase (RecQ)
EML485_RS12545	COG1072	(Pantothenic acid kinase))
EML485_RS12555	COG1780	Probably involved in ribonucleotide reductase function
EML485_RS12575	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EML485_RS12605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML485_RS12615	COG2813	Specifically methylates the guanine in position
EML485_RS12620	COG1185	polyribonucleotide nucleotidyltransferase activity
EML485_RS12625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EML485_RS12630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EML485_RS12635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EML485_RS12640	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EML485_RS12640	COG3064	Membrane
EML485_RS12655	COG0779	Required for maturation of 30S ribosomal subunits
EML485_RS12660	COG2814	Major facilitator Superfamily
EML485_RS12665	COG2951	lytic endotransglycosylase activity
EML485_RS12670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EML485_RS12680	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EML485_RS12685	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EML485_RS12700	COG2816	NAD+ diphosphatase activity
EML485_RS12705	COG0077	Prephenate dehydratase
EML485_RS12705	COG1605	Chorismate mutase
EML485_RS12710	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EML485_RS12715	COG3474	cytochrome
EML485_RS12725	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EML485_RS12730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EML485_RS12735	COG1278	Cold shock
EML485_RS12740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML485_RS12755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EML485_RS12755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EML485_RS12765	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EML485_RS12795	COG2900	Belongs to the SlyX family
EML485_RS12805	COG0484	heat shock protein binding
EML485_RS12810	COG0443	Heat shock 70 kDa protein
EML485_RS12825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EML485_RS12830	COG1744	ABC transporter substrate-binding protein PnrA-like
EML485_RS12835	COG3845	ABC transporter
EML485_RS12840	COG1079	Belongs to the binding-protein-dependent transport system permease family
EML485_RS12845	COG1079	Belongs to the binding-protein-dependent transport system permease family
EML485_RS12850	COG0295	cytidine deaminase activity
EML485_RS12855	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EML485_RS12860	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EML485_RS12865	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EML485_RS12875	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EML485_RS12880	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EML485_RS12885	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EML485_RS12895	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EML485_RS12900	COG1845	cytochrome c oxidase, subunit III
EML485_RS12905	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EML485_RS12915	COG0477	Major facilitator Superfamily
EML485_RS12920	COG0069	glutamate synthase activity
EML485_RS12920	COG0067	glutamate synthase
EML485_RS12920	COG0070	glutamate synthase
EML485_RS12925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EML485_RS12940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EML485_RS12950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EML485_RS12980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML485_RS13000	COG0848	biopolymer transport protein
EML485_RS13010	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EML485_RS13025	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EML485_RS13030	COG3454	Phosphonate metabolism
EML485_RS13035	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EML485_RS13040	COG3639	organic phosphonate transmembrane transporter activity
EML485_RS13045	COG3639	organic phosphonate transmembrane transporter activity
EML485_RS13050	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EML485_RS13055	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EML485_RS13065	COG4778	phosphonate C-P lyase system protein PhnL
EML485_RS13070	COG4107	phosphonate C-P lyase system protein PhnK
EML485_RS13075	COG3627	carbon phosphorus lyase activity
EML485_RS13080	COG3626	phosphonate metabolism
EML485_RS13085	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EML485_RS13090	COG3624	Phosphonate C-P lyase system protein PhnG
EML485_RS13095	COG2188	Transcriptional regulator
EML485_RS13100	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EML485_RS13105	COG0837	glucose binding
EML485_RS13110	COG1803	Methylglyoxal synthase
EML485_RS13115	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
EML485_RS13120	COG4166	transmembrane transport
EML485_RS13125	COG4174	ABC transporter (Permease)
EML485_RS13130	COG4239	(ABC) transporter, permease
EML485_RS13135	COG4172	Belongs to the ABC transporter superfamily
EML485_RS13145	COG0174	glutamine synthetase
EML485_RS13150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS13155	COG3265	gluconokinase activity
EML485_RS13160	COG1174	glycine betaine transport
EML485_RS13165	COG1125	glycine betaine transport
EML485_RS13170	COG1174	glycine betaine transport
EML485_RS13175	COG1732	Glycine betaine
EML485_RS13185	COG1959	2 iron, 2 sulfur cluster binding
EML485_RS13190	COG1840	ABC-type Fe3 transport system, periplasmic component
EML485_RS13200	COG4269	membrane
EML485_RS13220	COG0697	spore germination
EML485_RS13235	COG0791	NLP P60 protein
EML485_RS13245	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EML485_RS13250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EML485_RS13285	COG4964	Belongs to the GSP D family
EML485_RS13330	COG3422	double-strand break repair
EML485_RS13335	COG3757	hydrolase, family 25
EML485_RS13340	COG0697	spore germination
EML485_RS13345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EML485_RS13375	COG0481	GTPase activity
EML485_RS13380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EML485_RS13395	COG1396	sequence-specific DNA binding
EML485_RS13410	COG2169	Transcriptional regulator
EML485_RS13410	COG1917	Cupin 2, conserved barrel domain protein
EML485_RS13415	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EML485_RS13440	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EML485_RS13445	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EML485_RS13450	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EML485_RS13460	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EML485_RS13465	COG0072	phenylalanine-tRNA ligase activity
EML485_RS13465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EML485_RS13470	COG0667	Aldo Keto reductase
EML485_RS13485	COG0667	Aldo Keto reductase
EML485_RS13490	COG4977	sequence-specific DNA binding
EML485_RS13515	COG1570	exodeoxyribonuclease VII activity
EML485_RS13520	COG4948	Mandelate Racemase Muconate Lactonizing
EML485_RS13530	COG1846	Transcriptional regulator
EML485_RS13535	COG0697	spore germination
EML485_RS13540	COG2309	aminopeptidase activity
EML485_RS13545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EML485_RS13550	COG1393	Belongs to the ArsC family
EML485_RS13565	COG1309	transcriptional regulator
EML485_RS13575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EML485_RS13575	COG0519	Catalyzes the synthesis of GMP from XMP
EML485_RS13590	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EML485_RS13620	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EML485_RS13630	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EML485_RS13640	COG1968	undecaprenyl-diphosphatase activity
EML485_RS13660	COG0284	orotidine-5'-phosphate decarboxylase activity
EML485_RS13670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EML485_RS13680	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EML485_RS13685	COG0792	nuclease activity
EML485_RS13700	COG1175	transmembrane transport
EML485_RS13705	COG0395	ABC-type sugar transport system, permease component
EML485_RS13710	COG3842	ATPase activity
EML485_RS13720	COG0189	ligase activity
EML485_RS13725	COG0606	chelatase, subunit chli
EML485_RS13730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EML485_RS13735	COG1280	lysine exporter protein (LysE YggA)
EML485_RS13740	COG0756	dUTP diphosphatase activity
EML485_RS13745	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EML485_RS13750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EML485_RS13765	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EML485_RS13770	COG2226	methyltransferase
EML485_RS13775	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EML485_RS13780	COG1024	Enoyl-CoA hydratase
EML485_RS13785	COG0268	Binds directly to 16S ribosomal RNA
EML485_RS13815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EML485_RS13825	COG0640	Transcriptional regulator
EML485_RS13870	COG3842	ATPase activity
EML485_RS13875	COG4209	transmembrane transport
EML485_RS13880	COG0395	ABC-type sugar transport system, permease component
EML485_RS13885	COG1653	transport
EML485_RS13895	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS13905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EML485_RS13915	COG4948	Mandelate Racemase Muconate Lactonizing
EML485_RS13945	COG2197	response regulator
EML485_RS13950	COG0601	transmembrane transport
EML485_RS13955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS13975	COG0747	negative chemotaxis
EML485_RS13990	COG1446	asparaginase
EML485_RS14000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS14005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS14010	COG0601	transmembrane transport
EML485_RS14050	COG1215	transferase activity, transferring glycosyl groups
EML485_RS14060	COG0025	NhaP-type Na H and K H
EML485_RS14065	COG4178	(ABC) transporter
EML485_RS14075	COG1609	Transcriptional regulator
EML485_RS14090	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS14095	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EML485_RS14130	COG1794	racemase activity, acting on amino acids and derivatives
EML485_RS14135	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS14140	COG1309	transcriptional regulator
EML485_RS14145	COG2233	PERMEase
EML485_RS14185	COG1595	DNA-templated transcription, initiation
EML485_RS14195	COG0395	ABC-type sugar transport system, permease component
EML485_RS14200	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML485_RS14210	COG3842	ATPase activity
EML485_RS14245	COG1653	transport
EML485_RS14255	COG0395	ABC-type sugar transport system, permease component
EML485_RS14260	COG3842	ATPase activity
EML485_RS14265	COG0395	ABC-type sugar transport system, permease component
EML485_RS14270	COG1175	transmembrane transport
EML485_RS14300	COG1609	Transcriptional regulator
EML485_RS14310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EML485_RS14315	COG1082	Xylose isomerase domain protein TIM barrel
EML485_RS14320	COG3842	ATPase activity
EML485_RS14325	COG0395	ABC-type sugar transport system, permease component
EML485_RS14330	COG1175	transmembrane transport
EML485_RS14335	COG1653	transport
EML485_RS14340	COG1309	transcriptional regulator
EML485_RS14345	COG0673	inositol 2-dehydrogenase activity
EML485_RS14360	COG0673	inositol 2-dehydrogenase activity
EML485_RS14370	COG1278	Cold shock
EML485_RS14380	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EML485_RS14405	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EML485_RS14420	COG3842	ATPase activity
EML485_RS14425	COG0395	ABC-type sugar transport system, permease component
EML485_RS14430	COG1175	transmembrane transport
EML485_RS14450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EML485_RS14455	COG3618	amidohydrolase
EML485_RS14460	COG4948	Mandelate Racemase Muconate Lactonizing
EML485_RS14465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML485_RS14470	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS14475	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EML485_RS14480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML485_RS14485	COG2186	Transcriptional regulator
EML485_RS14535	COG2223	nitrite transmembrane transporter activity
EML485_RS14540	COG0583	DNA-binding transcription factor activity
EML485_RS14545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EML485_RS14555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EML485_RS14560	COG2084	Dehydrogenase
EML485_RS14575	COG1609	Transcriptional regulator
EML485_RS14580	COG1063	alcohol dehydrogenase
EML485_RS14585	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS14595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML485_RS14600	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
EML485_RS14605	COG1175	transmembrane transport
EML485_RS14610	COG0395	ABC-type sugar transport system, permease component
EML485_RS14625	COG0395	ABC-type sugar transport system, permease component
EML485_RS14630	COG1175	transmembrane transport
EML485_RS14635	COG2182	Extracellular solute-binding protein
EML485_RS14640	COG0626	cystathionine gamma-synthase activity
EML485_RS14655	COG0803	Belongs to the bacterial solute-binding protein 9 family
EML485_RS14665	COG1121	(ABC) transporter
EML485_RS14670	COG0523	cobalamin synthesis protein
EML485_RS14685	COG0523	cobalamin synthesis protein
EML485_RS14690	COG1653	transport
EML485_RS14695	COG1175	transmembrane transport
EML485_RS14700	COG0395	ABC-type sugar transport system, permease component
EML485_RS14705	COG3842	ATPase activity
EML485_RS14720	COG3047	cAMP biosynthetic process
EML485_RS14745	COG0583	DNA-binding transcription factor activity
EML485_RS14750	COG1879	ABC-type sugar transport system periplasmic component
EML485_RS14755	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS14760	COG1129	ABC transporter
EML485_RS14770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EML485_RS14775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML485_RS14780	COG5002	protein histidine kinase activity
EML485_RS14780	COG5001	Diguanylate cyclase
EML485_RS14780	COG3447	MASE1 domain protein
EML485_RS14785	COG3257	ureidoglycine aminohydrolase activity
EML485_RS14795	COG5001	Diguanylate cyclase
EML485_RS14800	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EML485_RS14815	COG0747	negative chemotaxis
EML485_RS14820	COG0601	transmembrane transport
EML485_RS14825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS14835	COG4608	Belongs to the ABC transporter superfamily
EML485_RS14840	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EML485_RS14850	COG0129	dihydroxy-acid dehydratase activity
EML485_RS14860	COG1879	ABC-type sugar transport system periplasmic component
EML485_RS14865	COG1129	ABC transporter
EML485_RS14870	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS14875	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS14880	COG2186	Transcriptional regulator
EML485_RS14890	COG0587	DNA-directed DNA polymerase activity
EML485_RS14920	COG0673	inositol 2-dehydrogenase activity
EML485_RS14930	COG3842	ATPase activity
EML485_RS14935	COG0395	ABC-type sugar transport system, permease component
EML485_RS14940	COG1175	transmembrane transport
EML485_RS14945	COG1653	transport
EML485_RS14955	COG0673	inositol 2-dehydrogenase activity
EML485_RS14970	COG5001	Diguanylate cyclase
EML485_RS14975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS14985	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EML485_RS14990	COG2894	cell division
EML485_RS14995	COG0850	regulation of cytokinetic process
EML485_RS15000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EML485_RS15005	COG2186	Transcriptional regulator
EML485_RS15010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EML485_RS15020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EML485_RS15025	COG1063	alcohol dehydrogenase
EML485_RS15030	COG1312	Catalyzes the dehydration of D-mannonate
EML485_RS15045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EML485_RS15050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EML485_RS15055	COG4172	Belongs to the ABC transporter superfamily
EML485_RS15060	COG1921	L-seryl-tRNASec selenium transferase activity
EML485_RS15075	COG3964	amidohydrolase
EML485_RS15085	COG0601	transmembrane transport
EML485_RS15090	COG0747	negative chemotaxis
EML485_RS15095	COG0438	transferase activity, transferring glycosyl groups
EML485_RS15120	COG2911	Protein conserved in bacteria
EML485_RS15120	COG3210	domain, Protein
EML485_RS15130	COG4989	oxidoreductase activity
EML485_RS15145	COG3842	ATPase activity
EML485_RS15150	COG1653	transport
EML485_RS15155	COG1175	transmembrane transport
EML485_RS15160	COG0395	ABC-type sugar transport system, permease component
EML485_RS15165	COG1501	Belongs to the glycosyl hydrolase 31 family
EML485_RS15170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML485_RS15175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML485_RS15180	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EML485_RS15185	COG0352	thiamine-phosphate diphosphorylase activity
EML485_RS15190	COG0351	phosphomethylpyrimidine kinase
EML485_RS15195	COG1522	sequence-specific DNA binding
EML485_RS15200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EML485_RS15205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS15220	COG2204	response regulator
EML485_RS15225	COG4191	Histidine kinase
EML485_RS15230	COG1301	dicarboxylic acid transport
EML485_RS15240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EML485_RS15245	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS15255	COG1473	amidohydrolase
EML485_RS15275	COG1215	transferase activity, transferring glycosyl groups
EML485_RS15285	COG2942	2-epimerase
EML485_RS15320	COG2197	response regulator
EML485_RS15350	COG3307	-O-antigen
EML485_RS15355	COG1596	polysaccharide export
EML485_RS15360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EML485_RS15370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EML485_RS15375	COG2972	Histidine kinase
EML485_RS15375	COG0840	transmembrane signaling receptor activity
EML485_RS15380	COG1376	ErfK ybiS ycfS ynhG family protein
EML485_RS15380	COG1388	LysM domain
EML485_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS15400	COG2094	Belongs to the DNA glycosylase MPG family
EML485_RS15420	COG1653	transport
EML485_RS15435	COG3842	ATPase activity
EML485_RS15445	COG0673	inositol 2-dehydrogenase activity
EML485_RS15450	COG0602	queuosine metabolic process
EML485_RS15455	COG0720	synthase
EML485_RS15460	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EML485_RS15465	COG0673	inositol 2-dehydrogenase activity
EML485_RS15480	COG0395	ABC-type sugar transport system, permease component
EML485_RS15485	COG1175	transmembrane transport
EML485_RS15505	COG0583	DNA-binding transcription factor activity
EML485_RS15510	COG0280	phosphate acetyltransferase
EML485_RS15510	COG0281	malic enzyme
EML485_RS15525	COG0765	amino acid transport
EML485_RS15530	COG1126	abc transporter atp-binding protein
EML485_RS15535	COG2079	MmgE PrpD family protein
EML485_RS15540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS15565	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EML485_RS15570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EML485_RS15575	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EML485_RS15580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EML485_RS15585	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS15590	COG1129	ABC transporter
EML485_RS15600	COG1473	amidohydrolase
EML485_RS15620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS15625	COG0601	transmembrane transport
EML485_RS15630	COG0583	DNA-binding transcription factor activity
EML485_RS15635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML485_RS15640	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
EML485_RS15660	COG1595	DNA-templated transcription, initiation
EML485_RS15665	COG1120	ATPase activity
EML485_RS15670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML485_RS15685	COG2226	methyltransferase
EML485_RS15695	COG1120	ATPase activity
EML485_RS15700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML485_RS15720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML485_RS15730	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS15735	COG0473	3-isopropylmalate dehydrogenase activity
EML485_RS15740	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS15745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS15775	COG0601	transmembrane transport
EML485_RS15780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS15785	COG4172	Belongs to the ABC transporter superfamily
EML485_RS15790	COG1522	sequence-specific DNA binding
EML485_RS15795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS15805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS15810	COG1126	abc transporter atp-binding protein
EML485_RS15820	COG1473	amidohydrolase
EML485_RS15825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS15830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS15835	COG1959	2 iron, 2 sulfur cluster binding
EML485_RS15845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EML485_RS15850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS15865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS15870	COG1960	acyl-CoA dehydrogenase activity
EML485_RS15905	COG0667	Aldo Keto reductase
EML485_RS15915	COG0583	DNA-binding transcription factor activity
EML485_RS15920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS15940	COG1473	amidohydrolase
EML485_RS15945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS15960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS15965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS15985	COG4608	Belongs to the ABC transporter superfamily
EML485_RS15990	COG0444	Belongs to the ABC transporter superfamily
EML485_RS16000	COG0601	transmembrane transport
EML485_RS16010	COG2186	Transcriptional regulator
EML485_RS16035	COG3453	Protein conserved in bacteria
EML485_RS16035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EML485_RS16040	COG0640	Transcriptional regulator
EML485_RS16050	COG2391	methyltransferase activity
EML485_RS16055	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EML485_RS16065	COG0022	dehydrogenase e1 component
EML485_RS16075	COG1960	acyl-CoA dehydrogenase activity
EML485_RS16080	COG0183	Belongs to the thiolase family
EML485_RS16090	COG1960	acyl-CoA dehydrogenase activity
EML485_RS16095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EML485_RS16110	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EML485_RS16115	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EML485_RS16120	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EML485_RS16125	COG4952	isomerase
EML485_RS16130	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS16130	COG3347	Dehydrogenase
EML485_RS16135	COG1349	DNA-binding transcription factor activity
EML485_RS16145	COG1129	ABC transporter
EML485_RS16150	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS16160	COG3254	rhamnose metabolic process
EML485_RS16175	COG2264	protein methyltransferase activity
EML485_RS16180	COG5001	Diguanylate cyclase
EML485_RS16200	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EML485_RS16205	COG4208	sulfate ABC transporter
EML485_RS16215	COG4150	thiosulfate binding
EML485_RS16235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EML485_RS16245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EML485_RS16255	COG1040	competence protein
EML485_RS16260	COG2226	methyltransferase
EML485_RS16275	COG0494	nUDIX hydrolase
EML485_RS16285	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EML485_RS16290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EML485_RS16295	COG0653	protein targeting
EML485_RS16300	COG0697	spore germination
EML485_RS16340	COG1312	Catalyzes the dehydration of D-mannonate
EML485_RS16345	COG0246	Mannitol dehydrogenase
EML485_RS16365	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS16370	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS16375	COG1129	ABC transporter
EML485_RS16405	COG2376	Dihydroxyacetone kinase
EML485_RS16410	COG0471	metal ion transport
EML485_RS16410	COG3273	potassium ion transport
EML485_RS16430	COG0438	transferase activity, transferring glycosyl groups
EML485_RS16440	COG2244	polysaccharide biosynthetic process
EML485_RS16465	COG0489	protein tyrosine kinase activity
EML485_RS16465	COG3206	protein involved in exopolysaccharide biosynthesis
EML485_RS16485	COG0438	transferase activity, transferring glycosyl groups
EML485_RS16490	COG0438	transferase activity, transferring glycosyl groups
EML485_RS16505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EML485_RS16510	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EML485_RS16510	COG2273	Hydrolase Family 16
EML485_RS16555	COG1396	sequence-specific DNA binding
EML485_RS16565	COG1129	ABC transporter
EML485_RS16570	COG4214	carbohydrate transport
EML485_RS16575	COG4213	ABC transporter substrate-binding protein
EML485_RS16590	COG0346	lactoylglutathione lyase activity
EML485_RS16595	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EML485_RS16595	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EML485_RS16600	COG4770	biotin carboxylase activity
EML485_RS16610	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EML485_RS16620	COG0625	glutathione transferase activity
EML485_RS16625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EML485_RS16630	COG3800	Transcriptional regulator
EML485_RS16630	COG1396	sequence-specific DNA binding
EML485_RS16640	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EML485_RS16650	COG0300	oxidoreductase activity
EML485_RS16660	COG2096	Adenosyltransferase
EML485_RS16670	COG2086	electron transfer activity
EML485_RS16680	COG1250	3-hydroxyacyl-CoA dehydrogenase
EML485_RS16685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EML485_RS16690	COG0165	Argininosuccinate lyase
EML485_RS16725	COG2884	Cell division ATP-binding protein ftsE
EML485_RS16745	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EML485_RS16755	COG0287	Prephenate dehydrogenase
EML485_RS16760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EML485_RS16765	COG2226	methyltransferase
EML485_RS16770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EML485_RS16785	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EML485_RS16790	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EML485_RS16825	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EML485_RS16830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EML485_RS16840	COG4974	Belongs to the 'phage' integrase family
EML485_RS16845	COG0825	malonyl-CoA metabolic process
EML485_RS16850	COG3034	peptidoglycan biosynthetic process
EML485_RS16855	COG0425	Belongs to the sulfur carrier protein TusA family
EML485_RS16855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EML485_RS16860	COG0523	cobalamin synthesis protein
EML485_RS16865	COG1686	Belongs to the peptidase S11 family
EML485_RS16870	COG1473	amidohydrolase
EML485_RS16880	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EML485_RS16950	COG0456	acetyltransferase
EML485_RS16985	COG2267	carboxylic ester hydrolase activity
EML485_RS16995	COG1959	2 iron, 2 sulfur cluster binding
EML485_RS17000	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EML485_RS17040	COG2226	methyltransferase
EML485_RS17075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EML485_RS17095	COG4774	siderophore transport
EML485_RS17095	COG1629	transport
EML485_RS17100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EML485_RS17105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML485_RS17110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML485_RS17115	COG1120	ATPase activity
EML485_RS17130	COG4953	penicillin-binding protein 1C
EML485_RS17135	COG2373	Large extracellular alpha-helical protein
EML485_RS17140	COG2835	tetraacyldisaccharide 4'-kinase activity
EML485_RS17150	COG3118	belongs to the thioredoxin family
EML485_RS17165	COG0625	glutathione transferase activity
EML485_RS17175	COG0482	sulfurtransferase activity
EML485_RS17190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML485_RS17205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EML485_RS17210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EML485_RS17215	COG0037	tRNA processing
EML485_RS17225	COG2885	chlorophyll binding
EML485_RS17230	COG0823	Involved in the tonB-independent uptake of proteins
EML485_RS17250	COG0824	Thioesterase
EML485_RS17260	COG0494	nUDIX hydrolase
EML485_RS17275	COG2255	four-way junction helicase activity
EML485_RS17280	COG0632	four-way junction helicase activity
EML485_RS17285	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EML485_RS17290	COG0840	transmembrane signaling receptor activity
EML485_RS17295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS17300	COG0217	transcriptional regulatory protein
EML485_RS17315	COG1692	metallophosphoesterase
EML485_RS17325	COG1253	flavin adenine dinucleotide binding
EML485_RS17355	COG3263	regulation of cellular component size
EML485_RS17360	COG0126	phosphoglycerate kinase activity
EML485_RS17365	COG3588	fructose-bisphosphate aldolase
EML485_RS17390	COG0254	rRNA binding
EML485_RS17395	COG1132	(ABC) transporter
EML485_RS17415	COG0483	inositol monophosphate 1-phosphatase activity
EML485_RS17445	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EML485_RS17450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EML485_RS17455	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EML485_RS17460	COG0457	Tetratricopeptide repeat
EML485_RS17465	COG3750	Belongs to the UPF0335 family
EML485_RS17485	COG0469	pyruvate kinase activity
EML485_RS17490	COG3108	Peptidase M15
EML485_RS17495	COG2204	response regulator
EML485_RS17500	COG1164	Oligoendopeptidase f
EML485_RS17505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EML485_RS17515	COG5310	Homospermidine synthase
EML485_RS17525	COG0737	Belongs to the 5'-nucleotidase family
EML485_RS17530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EML485_RS17535	COG0330	HflC and HflK could
EML485_RS17560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EML485_RS17565	COG2951	lytic endotransglycosylase activity
EML485_RS17580	COG2205	protein histidine kinase activity
EML485_RS17595	COG0070	glutamate synthase
EML485_RS17595	COG0069	glutamate synthase activity
EML485_RS17595	COG0067	glutamate synthase
EML485_RS17605	COG0745	RESPONSE REGULATOR receiver
EML485_RS17610	COG2205	protein histidine kinase activity
EML485_RS17615	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EML485_RS17620	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EML485_RS17630	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EML485_RS17640	COG0252	asparaginase activity
EML485_RS17650	COG1027	Aspartate ammonia-lyase
EML485_RS17655	COG2186	Transcriptional regulator
EML485_RS17695	COG4176	ABC-type proline glycine betaine transport system permease component
EML485_RS17700	COG4175	Glycine betaine
EML485_RS17700	COG0517	IMP dehydrogenase activity
EML485_RS17705	COG2986	histidine ammonia-lyase
EML485_RS17710	COG2814	Major facilitator Superfamily
EML485_RS17725	COG1522	sequence-specific DNA binding
EML485_RS17730	COG0583	DNA-binding transcription factor activity
EML485_RS17735	COG0667	Aldo Keto reductase
EML485_RS17745	COG1335	isochorismatase
EML485_RS17755	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS17760	COG3254	rhamnose metabolic process
EML485_RS17775	COG2721	sulfolactate sulfo-lyase activity
EML485_RS17780	COG1129	ABC transporter
EML485_RS17790	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS17795	COG1879	ABC-type sugar transport system periplasmic component
EML485_RS17985	COG2308	Evidence 4 Homologs of previously reported genes of
EML485_RS17985	COG2307	Protein conserved in bacteria
EML485_RS18000	COG0488	(ABC) transporter
EML485_RS18005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EML485_RS18010	COG1304	FMN binding
EML485_RS18020	COG1846	Transcriptional regulator
EML485_RS18035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EML485_RS18040	COG0667	Aldo Keto reductase
EML485_RS18050	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS18055	COG1129	ABC transporter
EML485_RS18060	COG1879	ABC-type sugar transport system periplasmic component
EML485_RS18095	COG0071	Belongs to the small heat shock protein (HSP20) family
EML485_RS18110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EML485_RS18125	COG0395	ABC-type sugar transport system, permease component
EML485_RS18140	COG3842	ATPase activity
EML485_RS18155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EML485_RS18155	COG1648	precorrin-2 dehydrogenase activity
EML485_RS18160	COG0243	molybdopterin cofactor binding
EML485_RS18170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EML485_RS18175	COG1116	anion transmembrane transporter activity
EML485_RS18180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML485_RS18185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML485_RS18195	COG3707	response regulator
EML485_RS18200	COG1802	Transcriptional regulator
EML485_RS18205	COG1914	H( )-stimulated, divalent metal cation uptake system
EML485_RS18210	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EML485_RS18215	COG4336	lyase activity
EML485_RS18220	COG1984	allophanate hydrolase subunit 2
EML485_RS18225	COG4770	biotin carboxylase activity
EML485_RS18230	COG0366	Alpha amylase catalytic
EML485_RS18240	COG4771	TonB-dependent receptor
EML485_RS18265	COG1414	Transcriptional regulator
EML485_RS18270	COG1475	DNA binding
EML485_RS18275	COG1192	Involved in chromosome partitioning
EML485_RS18310	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EML485_RS18320	COG2986	histidine ammonia-lyase
EML485_RS18325	COG1228	amidohydrolase
EML485_RS18330	COG0402	S-adenosylhomocysteine deaminase activity
EML485_RS18380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS18390	COG2423	ornithine cyclodeaminase activity
EML485_RS18405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS18410	COG3938	Belongs to the proline racemase family
EML485_RS18415	COG4176	ABC-type proline glycine betaine transport system permease component
EML485_RS18425	COG3448	diguanylate cyclase activity
EML485_RS18425	COG4175	Glycine betaine
EML485_RS18435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS18440	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS18445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML485_RS18470	COG0673	inositol 2-dehydrogenase activity
EML485_RS18475	COG0673	inositol 2-dehydrogenase activity
EML485_RS18485	COG1175	transmembrane transport
EML485_RS18490	COG0395	ABC-type sugar transport system, permease component
EML485_RS18495	COG3842	ATPase activity
EML485_RS18505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML485_RS18510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EML485_RS18535	COG0583	DNA-binding transcription factor activity
EML485_RS18540	COG0346	lactoylglutathione lyase activity
EML485_RS18555	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EML485_RS18565	COG2814	Major facilitator Superfamily
EML485_RS18580	COG0583	DNA-binding transcription factor activity
EML485_RS18585	COG0477	Major facilitator Superfamily
EML485_RS18635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EML485_RS18645	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EML485_RS18650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EML485_RS18655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EML485_RS18685	COG0010	Belongs to the arginase family
EML485_RS18705	COG0697	spore germination
EML485_RS18710	COG0673	inositol 2-dehydrogenase activity
EML485_RS18730	COG0477	Major facilitator Superfamily
EML485_RS18735	COG0642	Histidine kinase
EML485_RS18745	COG2194	sulfuric ester hydrolase activity
EML485_RS18750	COG0583	DNA-binding transcription factor activity
EML485_RS18755	COG4774	siderophore transport
EML485_RS18770	COG1120	ATPase activity
EML485_RS18780	COG3474	cytochrome
EML485_RS18785	COG2137	regulation of response to DNA damage stimulus
EML485_RS18790	COG3386	PFAM SMP-30 Gluconolaconase
EML485_RS18800	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS18805	COG1129	ABC transporter
EML485_RS18810	COG1879	ABC-type sugar transport system periplasmic component
EML485_RS18815	COG4585	Histidine kinase
EML485_RS18820	COG2197	response regulator
EML485_RS18830	COG2133	pyrroloquinoline quinone binding
EML485_RS18840	COG0500	methyltransferase
EML485_RS18845	COG0564	pseudouridine synthase activity
EML485_RS18860	COG0517	IMP dehydrogenase activity
EML485_RS18860	COG4175	Glycine betaine
EML485_RS18865	COG4176	ABC-type proline glycine betaine transport system permease component
EML485_RS18875	COG0784	Response regulator, receiver
EML485_RS18875	COG4191	Histidine kinase
EML485_RS18880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML485_RS18885	COG0489	protein tyrosine kinase activity
EML485_RS18885	COG3206	protein involved in exopolysaccharide biosynthesis
EML485_RS18890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EML485_RS18895	COG1215	transferase activity, transferring glycosyl groups
EML485_RS18900	COG1215	transferase activity, transferring glycosyl groups
EML485_RS18905	COG1215	transferase activity, transferring glycosyl groups
EML485_RS18910	COG0438	transferase activity, transferring glycosyl groups
EML485_RS18915	COG2273	Hydrolase Family 16
EML485_RS18920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EML485_RS18925	COG2244	polysaccharide biosynthetic process
EML485_RS18930	COG0463	Glycosyl transferase, family 2
EML485_RS18935	COG2327	Polysaccharide pyruvyl transferase
EML485_RS18940	COG1215	transferase activity, transferring glycosyl groups
EML485_RS18960	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EML485_RS18965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS18980	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML485_RS18980	COG0446	pyridine nucleotide-disulphide oxidoreductase
EML485_RS19005	COG0033	Phosphoglucomutase
EML485_RS19010	COG0297	glycogen (starch) synthase activity
EML485_RS19015	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EML485_RS19020	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EML485_RS19025	COG0058	SHG alpha-glucan phosphorylase activity
EML485_RS19035	COG1794	racemase activity, acting on amino acids and derivatives
EML485_RS19040	COG1522	sequence-specific DNA binding
EML485_RS19050	COG2084	Dehydrogenase
EML485_RS19055	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS19060	COG1063	alcohol dehydrogenase
EML485_RS19070	COG4988	ABC transporter
EML485_RS19075	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EML485_RS19085	COG1294	oxidase, subunit
EML485_RS19115	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EML485_RS19120	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EML485_RS19150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EML485_RS19155	COG0539	negative regulation of cytoplasmic translation
EML485_RS19185	COG4221	oxidoreductase activity
EML485_RS19190	COG0006	proline dipeptidase activity
EML485_RS19195	COG0747	negative chemotaxis
EML485_RS19200	COG0601	transmembrane transport
EML485_RS19205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS19210	COG0444	Belongs to the ABC transporter superfamily
EML485_RS19215	COG4608	Belongs to the ABC transporter superfamily
EML485_RS19230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS19255	COG0559	Belongs to the binding-protein-dependent transport system permease family
EML485_RS19275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EML485_RS19280	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS19300	COG4993	Dehydrogenase
EML485_RS19305	COG3685	Protein conserved in bacteria
EML485_RS19335	COG0693	protein deglycase activity
EML485_RS19355	COG0189	ligase activity
EML485_RS19360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML485_RS19365	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EML485_RS19375	COG0583	DNA-binding transcription factor activity
EML485_RS19380	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS19385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML485_RS19390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML485_RS19395	COG1116	anion transmembrane transporter activity
EML485_RS19405	COG1522	sequence-specific DNA binding
EML485_RS19420	COG0784	Response regulator, receiver
EML485_RS19430	COG3920	Histidine kinase
EML485_RS19440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EML485_RS19455	COG0019	diaminopimelate decarboxylase activity
EML485_RS19465	COG0513	Belongs to the DEAD box helicase family
EML485_RS19470	COG0527	aspartate kinase activity
EML485_RS19480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EML485_RS19485	COG2890	protein-(glutamine-N5) methyltransferase activity
EML485_RS19495	COG0542	response to heat
EML485_RS19500	COG0741	lytic transglycosylase activity
EML485_RS19500	COG1196	nuclear chromosome segregation
EML485_RS19500	COG0739	heme binding
EML485_RS19540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML485_RS19550	COG2186	Transcriptional regulator
EML485_RS19555	COG0747	negative chemotaxis
EML485_RS19560	COG0601	transmembrane transport
EML485_RS19565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS19570	COG4172	Belongs to the ABC transporter superfamily
EML485_RS19575	COG4948	Mandelate Racemase Muconate Lactonizing
EML485_RS19610	COG1881	PFAM PEBP family protein
EML485_RS19645	COG3833	ABC-type maltose transport systems, permease component
EML485_RS19655	COG0584	glycerophosphoryl diester phosphodiesterase
EML485_RS19660	COG1278	Cold shock
EML485_RS19670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EML485_RS19690	COG0300	oxidoreductase activity
EML485_RS19700	COG0446	pyridine nucleotide-disulphide oxidoreductase
EML485_RS19700	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML485_RS19705	COG4311	Sarcosine oxidase, delta subunit
EML485_RS19710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS19715	COG4977	sequence-specific DNA binding
EML485_RS19725	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EML485_RS19730	COG2218	PFAM glutamate synthase alpha subunit domain protein
EML485_RS19735	COG0069	glutamate synthase activity
EML485_RS19740	COG0174	glutamine synthetase
EML485_RS19760	COG0765	amino acid transport
EML485_RS19765	COG1126	abc transporter atp-binding protein
EML485_RS19770	COG1454	alcohol dehydrogenase
EML485_RS19780	COG2267	carboxylic ester hydrolase activity
EML485_RS19790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS19795	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS19815	COG1177	transmembrane transport
EML485_RS19820	COG3842	ATPase activity
EML485_RS19835	COG3842	ATPase activity
EML485_RS19840	COG0395	ABC-type sugar transport system, permease component
EML485_RS19845	COG1175	transmembrane transport
EML485_RS19855	COG3976	FMN-binding domain protein
EML485_RS19855	COG1053	succinate dehydrogenase
EML485_RS19860	COG1609	Transcriptional regulator
EML485_RS19870	COG4172	Belongs to the ABC transporter superfamily
EML485_RS19875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS19880	COG0601	transmembrane transport
EML485_RS19890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML485_RS19905	COG2828	Protein conserved in bacteria
EML485_RS19910	COG0583	DNA-binding transcription factor activity
EML485_RS19920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EML485_RS19940	COG0494	nUDIX hydrolase
EML485_RS19945	COG0583	DNA-binding transcription factor activity
EML485_RS19955	COG0511	ligase activity, forming carbon-carbon bonds
EML485_RS19960	COG0439	Biotin carboxylase
EML485_RS19975	COG1984	allophanate hydrolase subunit 2
EML485_RS19980	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EML485_RS19985	COG0436	Aminotransferase
EML485_RS19995	COG4221	oxidoreductase activity
EML485_RS20000	COG0765	amino acid transport
EML485_RS20005	COG0765	amino acid transport
EML485_RS20010	COG1126	abc transporter atp-binding protein
EML485_RS20015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS20020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EML485_RS20035	COG0583	DNA-binding transcription factor activity
EML485_RS20045	COG0583	DNA-binding transcription factor activity
EML485_RS20050	COG2814	Major facilitator Superfamily
EML485_RS20065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EML485_RS20075	COG2207	Transcriptional regulator
EML485_RS20080	COG0668	transmembrane transport
EML485_RS20090	COG4566	intracellular signal transduction
EML485_RS20110	COG0668	transmembrane transport
EML485_RS20115	COG4191	Histidine kinase
EML485_RS20120	COG2205	protein histidine kinase activity
EML485_RS20120	COG0784	Response regulator, receiver
EML485_RS20120	COG5002	protein histidine kinase activity
EML485_RS20125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EML485_RS20135	COG0047	phosphoribosylformylglycinamidine synthase activity
EML485_RS20150	COG0446	pyridine nucleotide-disulphide oxidoreductase
EML485_RS20150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML485_RS20160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EML485_RS20175	COG1309	transcriptional regulator
EML485_RS20180	COG1063	alcohol dehydrogenase
EML485_RS20190	COG1879	ABC-type sugar transport system periplasmic component
EML485_RS20200	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS20350	COG5001	Diguanylate cyclase
EML485_RS20360	COG1253	flavin adenine dinucleotide binding
EML485_RS20375	COG3842	ATPase activity
EML485_RS20380	COG0395	ABC-type sugar transport system, permease component
EML485_RS20385	COG1175	transmembrane transport
EML485_RS20390	COG1653	transport
EML485_RS20400	COG0673	inositol 2-dehydrogenase activity
EML485_RS20405	COG1609	Transcriptional regulator
EML485_RS20420	COG0583	DNA-binding transcription factor activity
EML485_RS20430	COG1879	ABC-type sugar transport system periplasmic component
EML485_RS20435	COG1129	ABC transporter
EML485_RS20440	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS20445	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS20450	COG1609	Transcriptional regulator
EML485_RS20460	COG0673	inositol 2-dehydrogenase activity
EML485_RS20520	COG0714	Associated with various cellular activities
EML485_RS20525	COG3256	nitric oxide reductase
EML485_RS20555	COG0163	prenyltransferase activity
EML485_RS20560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EML485_RS20565	COG3189	MarR family transcriptional regulator
EML485_RS20575	COG0826	peptidase U32
EML485_RS20615	COG4459	periplasmic nitrate reductase
EML485_RS20630	COG0243	molybdopterin cofactor binding
EML485_RS20640	COG3005	denitrification pathway
EML485_RS20645	COG0583	DNA-binding transcription factor activity
EML485_RS20655	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
EML485_RS20660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML485_RS20675	COG1960	acyl-CoA dehydrogenase activity
EML485_RS20680	COG0583	DNA-binding transcription factor activity
EML485_RS20685	COG1609	Transcriptional regulator
EML485_RS20695	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML485_RS20705	COG3842	ATPase activity
EML485_RS20715	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EML485_RS20725	COG1473	amidohydrolase
EML485_RS20740	COG0747	negative chemotaxis
EML485_RS20745	COG0601	transmembrane transport
EML485_RS20750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS20755	COG0444	Belongs to the ABC transporter superfamily
EML485_RS20760	COG4608	Belongs to the ABC transporter superfamily
EML485_RS20770	COG0583	DNA-binding transcription factor activity
EML485_RS20775	COG0747	negative chemotaxis
EML485_RS20785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS20790	COG0154	amidase activity
EML485_RS20795	COG0693	protein deglycase activity
EML485_RS20805	COG1473	amidohydrolase
EML485_RS20810	COG4172	Belongs to the ABC transporter superfamily
EML485_RS20815	COG2390	Transcriptional regulator
EML485_RS20825	COG1175	transmembrane transport
EML485_RS20830	COG0395	ABC-type sugar transport system, permease component
EML485_RS20845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EML485_RS20850	COG1069	ribulokinase activity
EML485_RS20855	COG1737	Transcriptional regulator
EML485_RS20875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EML485_RS20895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EML485_RS20900	COG1414	Transcriptional regulator
EML485_RS20905	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS20915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EML485_RS20920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EML485_RS20925	COG1121	(ABC) transporter
EML485_RS20930	COG0803	Belongs to the bacterial solute-binding protein 9 family
EML485_RS20940	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EML485_RS20945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EML485_RS20950	COG3273	potassium ion transport
EML485_RS20950	COG0471	metal ion transport
EML485_RS20955	COG1253	flavin adenine dinucleotide binding
EML485_RS20960	COG1309	transcriptional regulator
EML485_RS20980	COG1609	Transcriptional regulator
EML485_RS20985	COG1070	Carbohydrate kinase
EML485_RS20990	COG2115	Belongs to the xylose isomerase family
EML485_RS21000	COG0778	Nitroreductase
EML485_RS21005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EML485_RS21010	COG2011	ABC-type metal ion transport system permease component
EML485_RS21020	COG5001	Diguanylate cyclase
EML485_RS21020	COG3300	MHYT domain
EML485_RS21025	COG1054	Belongs to the UPF0176 family
EML485_RS21035	COG2954	triphosphatase activity
EML485_RS21040	COG0800	Aldolase
EML485_RS21060	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EML485_RS21080	COG0523	cobalamin synthesis protein
EML485_RS21090	COG1846	Transcriptional regulator
EML485_RS21095	COG1609	Transcriptional regulator
EML485_RS21100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EML485_RS21105	COG0673	inositol 2-dehydrogenase activity
EML485_RS21110	COG3718	enzyme involved in inositol metabolism
EML485_RS21120	COG3962	Belongs to the TPP enzyme family
EML485_RS21125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML485_RS21140	COG0411	ABC transporter
EML485_RS21155	COG0683	leucine binding
EML485_RS21175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS21185	COG0747	negative chemotaxis
EML485_RS21200	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EML485_RS21200	COG1082	Xylose isomerase domain protein TIM barrel
EML485_RS21210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EML485_RS21215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EML485_RS21220	COG1126	abc transporter atp-binding protein
EML485_RS21225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS21230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS21235	COG0765	amino acid transport
EML485_RS21240	COG0765	amino acid transport
EML485_RS21250	COG3485	protocatechuate 3,4-dioxygenase
EML485_RS21255	COG3485	protocatechuate 3,4-dioxygenase
EML485_RS21260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EML485_RS21270	COG0583	DNA-binding transcription factor activity
EML485_RS21285	COG1414	Transcriptional regulator
EML485_RS21295	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EML485_RS21300	COG0183	Belongs to the thiolase family
EML485_RS21305	COG1609	Transcriptional regulator
EML485_RS21320	COG1082	Xylose isomerase domain protein TIM barrel
EML485_RS21325	COG0673	inositol 2-dehydrogenase activity
EML485_RS21335	COG1609	Transcriptional regulator
EML485_RS21340	COG0395	ABC-type sugar transport system, permease component
EML485_RS21345	COG1175	transmembrane transport
EML485_RS21350	COG3842	ATPase activity
EML485_RS21360	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EML485_RS21380	COG1940	carbohydrate kinase activity
EML485_RS21390	COG3842	ATPase activity
EML485_RS21395	COG4149	molybdate abc transporter
EML485_RS21405	COG0584	glycerophosphoryl diester phosphodiesterase
EML485_RS21410	COG0483	inositol monophosphate 1-phosphatase activity
EML485_RS21415	COG0300	oxidoreductase activity
EML485_RS21435	COG3842	ATPase activity
EML485_RS21455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EML485_RS21490	COG0667	Aldo Keto reductase
EML485_RS21495	COG0583	DNA-binding transcription factor activity
EML485_RS21505	COG0179	Fumarylacetoacetate (FAA) hydrolase
EML485_RS21515	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS21525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML485_RS21540	COG1132	(ABC) transporter
EML485_RS21575	COG1215	transferase activity, transferring glycosyl groups
EML485_RS21590	COG1215	transferase activity, transferring glycosyl groups
EML485_RS21600	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EML485_RS21605	COG1091	dTDP-4-dehydrorhamnose reductase activity
EML485_RS21610	COG1088	dTDP-glucose 4,6-dehydratase activity
EML485_RS21615	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EML485_RS21630	COG0444	Belongs to the ABC transporter superfamily
EML485_RS21635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS21640	COG0601	transmembrane transport
EML485_RS21645	COG2186	Transcriptional regulator
EML485_RS21650	COG1312	Catalyzes the dehydration of D-mannonate
EML485_RS21655	COG0747	negative chemotaxis
EML485_RS21665	COG5001	Diguanylate cyclase
EML485_RS21665	COG3300	MHYT domain
EML485_RS21670	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS21680	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EML485_RS21695	COG1392	Phosphate transport regulator
EML485_RS21720	COG5002	protein histidine kinase activity
EML485_RS21735	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EML485_RS21750	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS21765	COG3119	arylsulfatase activity
EML485_RS21770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML485_RS21775	COG3842	ATPase activity
EML485_RS21780	COG0165	Argininosuccinate lyase
EML485_RS21785	COG0395	ABC-type sugar transport system, permease component
EML485_RS21790	COG1175	transmembrane transport
EML485_RS21795	COG2182	Extracellular solute-binding protein
EML485_RS21800	COG1940	carbohydrate kinase activity
EML485_RS21825	COG1486	melibiose metabolic process
EML485_RS21830	COG0747	negative chemotaxis
EML485_RS21835	COG0601	transmembrane transport
EML485_RS21840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS21845	COG4172	Belongs to the ABC transporter superfamily
EML485_RS21850	COG1486	melibiose metabolic process
EML485_RS21855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML485_RS21860	COG1129	ABC transporter
EML485_RS21860	COG0842	Transport permease protein
EML485_RS21865	COG0842	Transport permease protein
EML485_RS21880	COG0784	Response regulator, receiver
EML485_RS21885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EML485_RS21895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML485_RS21900	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EML485_RS21915	COG0765	amino acid transport
EML485_RS21925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML485_RS21935	COG3938	Belongs to the proline racemase family
EML485_RS21950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS21955	COG0765	amino acid transport
EML485_RS21960	COG0765	amino acid transport
EML485_RS21970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EML485_RS21985	COG0402	S-adenosylhomocysteine deaminase activity
EML485_RS21995	COG0601	transmembrane transport
EML485_RS22000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS22010	COG0402	S-adenosylhomocysteine deaminase activity
EML485_RS22015	COG0444	Belongs to the ABC transporter superfamily
EML485_RS22020	COG4608	Belongs to the ABC transporter superfamily
EML485_RS22025	COG1802	Transcriptional regulator
EML485_RS22030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EML485_RS22055	COG3383	formate dehydrogenase (NAD+) activity
EML485_RS22065	COG2223	nitrite transmembrane transporter activity
EML485_RS22095	COG3237	CsbD-like
EML485_RS22100	COG2197	response regulator
EML485_RS22105	COG2186	Transcriptional regulator
EML485_RS22110	COG0747	negative chemotaxis
EML485_RS22115	COG0601	transmembrane transport
EML485_RS22120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS22125	COG0405	Gamma-glutamyltransferase
EML485_RS22135	COG3237	CsbD-like
EML485_RS22145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EML485_RS22150	COG3181	Tripartite tricarboxylate transporter family receptor
EML485_RS22155	COG5265	(ABC) transporter
EML485_RS22160	COG0488	(ABC) transporter
EML485_RS22185	COG1049	propionate catabolic process, 2-methylcitrate cycle
EML485_RS22190	COG0840	transmembrane signaling receptor activity
EML485_RS22200	COG0110	maltose O-acetyltransferase activity
EML485_RS22210	COG1063	alcohol dehydrogenase
EML485_RS22215	COG3284	Transcriptional regulator
EML485_RS22235	COG1129	ABC transporter
EML485_RS22240	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS22245	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS22260	COG1082	Xylose isomerase domain protein TIM barrel
EML485_RS22270	COG1126	abc transporter atp-binding protein
EML485_RS22275	COG0765	amino acid transport
EML485_RS22280	COG0765	amino acid transport
EML485_RS22285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS22290	COG3608	succinylglutamate desuccinylase aspartoacylase
EML485_RS22295	COG0006	proline dipeptidase activity
EML485_RS22300	COG2423	ornithine cyclodeaminase activity
EML485_RS22305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EML485_RS22310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EML485_RS22315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EML485_RS22320	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS22325	COG1522	sequence-specific DNA binding
EML485_RS22335	COG3046	protein related to deoxyribodipyrimidine photolyase
EML485_RS22365	COG2140	Oxalate decarboxylase
EML485_RS22380	COG4566	intracellular signal transduction
EML485_RS22390	COG0243	molybdopterin cofactor binding
EML485_RS22395	COG0783	Belongs to the Dps family
EML485_RS22415	COG4191	Histidine kinase
EML485_RS22415	COG0784	Response regulator, receiver
EML485_RS22425	COG1840	ABC-type Fe3 transport system, periplasmic component
EML485_RS22430	COG1840	ABC-type Fe3 transport system, periplasmic component
EML485_RS22440	COG3842	ATPase activity
EML485_RS22445	COG0483	inositol monophosphate 1-phosphatase activity
EML485_RS22460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML485_RS22485	COG2197	response regulator
EML485_RS22490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EML485_RS22495	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EML485_RS22505	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EML485_RS22510	COG4310	Domain of unknown function (DUF2172)
EML485_RS22515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML485_RS22520	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EML485_RS22525	COG2197	response regulator
EML485_RS22530	COG4566	intracellular signal transduction
EML485_RS22560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EML485_RS22580	COG0438	transferase activity, transferring glycosyl groups
EML485_RS22595	COG1522	sequence-specific DNA binding
EML485_RS22615	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS22630	COG1414	Transcriptional regulator
EML485_RS22640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EML485_RS22660	COG0582	viral genome integration into host DNA
EML485_RS22680	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EML485_RS22710	COG1349	DNA-binding transcription factor activity
EML485_RS22715	COG1879	ABC-type sugar transport system periplasmic component
EML485_RS22720	COG1129	ABC transporter
EML485_RS22725	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS22730	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS22750	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS22825	COG1846	Transcriptional regulator
EML485_RS22845	COG0667	Aldo Keto reductase
EML485_RS22855	COG0604	alcohol dehydrogenase
EML485_RS22865	COG1309	transcriptional regulator
EML485_RS22880	COG0667	Aldo Keto reductase
EML485_RS22885	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS22900	COG0662	Cupin 2, conserved barrel domain protein
EML485_RS22900	COG2207	Transcriptional regulator
EML485_RS22960	COG4584	PFAM Integrase catalytic
EML485_RS22980	COG1192	Involved in chromosome partitioning
EML485_RS22985	COG1475	DNA binding
EML485_RS22990	COG0640	Transcriptional regulator
EML485_RS23005	COG1126	abc transporter atp-binding protein
EML485_RS23010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS23015	COG1609	Transcriptional regulator
EML485_RS23095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EML485_RS23100	COG0210	DNA helicase
EML485_RS23160	COG3177	Filamentation induced by cAMP protein fic
EML485_RS23235	COG0071	Belongs to the small heat shock protein (HSP20) family
EML485_RS23270	COG1175	transmembrane transport
EML485_RS23275	COG0395	ABC-type sugar transport system, permease component
EML485_RS23285	COG3842	ATPase activity
EML485_RS23290	COG1737	Transcriptional regulator
EML485_RS23295	COG1846	Transcriptional regulator
EML485_RS23310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML485_RS23320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS23325	COG0601	transmembrane transport
EML485_RS23330	COG0747	negative chemotaxis
EML485_RS23340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EML485_RS23345	COG1454	alcohol dehydrogenase
EML485_RS23355	COG3395	kinase activity
EML485_RS23365	COG1609	Transcriptional regulator
EML485_RS23405	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EML485_RS23410	COG3920	Histidine kinase
EML485_RS23420	COG1215	transferase activity, transferring glycosyl groups
EML485_RS23465	COG0587	DNA-directed DNA polymerase activity
EML485_RS23485	COG5489	Protein of unknown function (DUF736)
EML485_RS23500	COG3831	ATPase activity
EML485_RS23505	COG3505	Type IV secretory pathway VirD4
EML485_RS23555	COG0156	8-amino-7-oxononanoate synthase activity
EML485_RS23560	COG0745	RESPONSE REGULATOR receiver
EML485_RS23570	COG0745	RESPONSE REGULATOR receiver
EML485_RS23575	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS23580	COG0028	Belongs to the TPP enzyme family
EML485_RS23585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EML485_RS23595	COG3842	ATPase activity
EML485_RS23600	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML485_RS23605	COG1177	transmembrane transport
EML485_RS23630	COG1414	Transcriptional regulator
EML485_RS23640	COG1454	alcohol dehydrogenase
EML485_RS23645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EML485_RS23675	COG1285	pathogenesis
EML485_RS23695	COG1733	regulation of RNA biosynthetic process
EML485_RS23735	COG3838	Conjugal transfer protein Trbc
EML485_RS23740	COG3702	type iv secretory pathway
EML485_RS23745	COG3451	type IV secretory pathway VirB4
EML485_RS23760	COG3704	protein secretion by the type IV secretion system
EML485_RS23770	COG3736	Type IV secretory pathway, component VirB8
EML485_RS23775	COG3504	Conjugal transfer protein
EML485_RS23780	COG2948	multi-organism process
EML485_RS23785	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EML485_RS23800	COG0745	RESPONSE REGULATOR receiver
EML485_RS23810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML485_RS23815	COG0577	efflux transmembrane transporter activity
EML485_RS23815	COG1136	(ABC) transporter
EML485_RS23825	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS23830	COG1063	alcohol dehydrogenase
EML485_RS23840	COG0583	DNA-binding transcription factor activity
EML485_RS23845	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS23850	COG0583	DNA-binding transcription factor activity
EML485_RS23865	COG2267	carboxylic ester hydrolase activity
EML485_RS23870	COG0673	inositol 2-dehydrogenase activity
EML485_RS23880	COG0789	Transcriptional regulator
EML485_RS23890	COG1376	ErfK ybiS ycfS ynhG family protein
EML485_RS23900	COG0667	Aldo Keto reductase
EML485_RS23905	COG0673	inositol 2-dehydrogenase activity
EML485_RS23930	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS23940	COG0583	DNA-binding transcription factor activity
EML485_RS23950	COG0583	DNA-binding transcription factor activity
EML485_RS23960	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS23965	COG1846	Transcriptional regulator
EML485_RS23980	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS23995	COG4176	ABC-type proline glycine betaine transport system permease component
EML485_RS24000	COG2113	Glycine betaine
EML485_RS24005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML485_RS24030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS24035	COG1012	belongs to the aldehyde dehydrogenase family
EML485_RS24065	COG0765	amino acid transport
EML485_RS24080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS24085	COG3608	succinylglutamate desuccinylase aspartoacylase
EML485_RS24090	COG1609	Transcriptional regulator
EML485_RS24110	COG0583	DNA-binding transcription factor activity
EML485_RS24125	COG1177	transmembrane transport
EML485_RS24130	COG3842	ATPase activity
EML485_RS24135	COG2072	flavoprotein involved in K transport
EML485_RS24155	COG0534	Mate efflux family protein
EML485_RS24175	COG1609	Transcriptional regulator
EML485_RS24180	COG1082	Xylose isomerase domain protein TIM barrel
EML485_RS24185	COG0673	inositol 2-dehydrogenase activity
EML485_RS24190	COG1082	Xylose isomerase domain protein TIM barrel
EML485_RS24200	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS24220	COG0840	transmembrane signaling receptor activity
EML485_RS24220	COG2972	Histidine kinase
EML485_RS24230	COG4221	oxidoreductase activity
EML485_RS24235	COG1902	pentaerythritol trinitrate reductase activity
EML485_RS24240	COG0596	Alpha beta hydrolase
EML485_RS24250	COG3831	ATPase activity
EML485_RS24255	COG0071	Belongs to the small heat shock protein (HSP20) family
EML485_RS24270	COG0577	efflux transmembrane transporter activity
EML485_RS24285	COG3734	2-keto-3-deoxy-galactonokinase
EML485_RS24290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML485_RS24295	COG4948	Mandelate Racemase Muconate Lactonizing
EML485_RS24305	COG1175	transmembrane transport
EML485_RS24310	COG0395	ABC-type sugar transport system, permease component
EML485_RS24315	COG3842	ATPase activity
EML485_RS24320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EML485_RS24325	COG1414	Transcriptional regulator
EML485_RS24330	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS24335	COG3158	transport of potassium into the cell
EML485_RS24345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EML485_RS24375	COG0504	CTP synthase activity
EML485_RS24380	COG0006	proline dipeptidase activity
EML485_RS24385	COG4948	Mandelate Racemase Muconate Lactonizing
EML485_RS24390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML485_RS24400	COG0765	amino acid transport
EML485_RS24405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML485_RS24450	COG0753	catalase activity
EML485_RS24465	COG3685	Protein conserved in bacteria
EML485_RS24475	COG1309	transcriptional regulator
EML485_RS24480	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EML485_RS24485	COG2080	2 iron, 2 sulfur cluster binding
EML485_RS24490	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EML485_RS24495	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EML485_RS24500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EML485_RS24540	COG4191	Histidine kinase
EML485_RS24540	COG0784	Response regulator, receiver
EML485_RS24545	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EML485_RS24560	COG1278	Cold shock
EML485_RS24600	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS24625	COG3920	Histidine kinase
EML485_RS24675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EML485_RS24685	COG1566	PFAM secretion protein HlyD family protein
EML485_RS24705	COG2207	Transcriptional regulator
EML485_RS24730	COG1192	Involved in chromosome partitioning
EML485_RS24735	COG1475	DNA binding
EML485_RS24740	COG0640	Transcriptional regulator
EML485_RS24745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EML485_RS24790	COG0583	DNA-binding transcription factor activity
EML485_RS24800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML485_RS24805	COG1116	anion transmembrane transporter activity
EML485_RS24810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML485_RS24820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS24825	COG1028	Short-chain dehydrogenase reductase Sdr
EML485_RS24855	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML485_RS24860	COG1129	ABC transporter
EML485_RS24885	COG4172	Belongs to the ABC transporter superfamily
EML485_RS24890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS24895	COG0601	transmembrane transport
EML485_RS24905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS24910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS24915	COG0583	DNA-binding transcription factor activity
EML485_RS24925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EML485_RS24935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML485_RS24940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML485_RS24945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML485_RS25025	COG1475	DNA binding
EML485_RS25045	COG2824	Alkylphosphonate utilization operon protein PhnA
EML485_RS25065	COG5489	Protein of unknown function (DUF736)
EML485_RS25090	COG0494	nUDIX hydrolase
EML485_RS25095	COG5489	Protein of unknown function (DUF736)
EML485_RS25185	COG1283	sodium-dependent phosphate transmembrane transporter activity
EML485_RS25200	COG0747	negative chemotaxis
EML485_RS25220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML485_RS25225	COG0584	glycerophosphoryl diester phosphodiesterase
EML485_RS25230	COG0483	inositol monophosphate 1-phosphatase activity
EML485_RS25290	COG3161	chorismate lyase activity
EML485_RS25435	COG3436	PFAM IS66 Orf2 family protein
EML485_RS25485	COG0583	DNA-binding transcription factor activity
EML485_RS25535	COG3701	Conjugal transfer protein
EML485_RS25540	COG3846	protein secretion by the type IV secretion system
EML485_RS25550	COG5314	conjugation
EML485_RS25555	COG3451	type IV secretory pathway VirB4
EML485_RS25570	COG4962	Type ii secretion system protein e