locus-tag	class	description
FY134_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY134_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY134_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY134_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY134_RS00025	COG1420	regulation of RNA biosynthetic process
FY134_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY134_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY134_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY134_RS00050	COG1137	ATPase activity
FY134_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY134_RS00065	COG0616	signal peptide processing
FY134_RS00070	COG0776	regulation of translation
FY134_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY134_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY134_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY134_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY134_RS00115	COG0728	peptidoglycan biosynthetic process
FY134_RS00125	COG0180	Tryptophanyl-tRNA synthetase
FY134_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY134_RS00140	COG1214	PFAM Peptidase M22, glycoprotease
FY134_RS00145	COG0456	acetyltransferase
FY134_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY134_RS00165	COG1702	phosphate starvation-inducible protein PhoH
FY134_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY134_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY134_RS00185	COG1396	sequence-specific DNA binding
FY134_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY134_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY134_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_RS00210	COG0242	peptide deformylase activity
FY134_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY134_RS00220	COG0101	tRNA pseudouridine synthase activity
FY134_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY134_RS00235	COG2171	N-acyltransferase activity
FY134_RS00245	COG0840	transmembrane signaling receptor activity
FY134_RS00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY134_RS00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY134_RS00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY134_RS00295	COG0706	membrane insertase activity
FY134_RS00300	COG0594	ribonuclease P activity
FY134_RS00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY134_RS00310	COG0840	transmembrane signaling receptor activity
FY134_RS00325	COG2226	methyltransferase
FY134_RS00330	COG3842	ATPase activity
FY134_RS00335	COG1175	transmembrane transport
FY134_RS00340	COG0395	ABC-type sugar transport system, permease component
FY134_RS00355	COG0427	acetyl-CoA hydrolase
FY134_RS00365	COG3938	Belongs to the proline racemase family
FY134_RS00370	COG0418	dihydroorotase activity
FY134_RS00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY134_RS00395	COG0166	Belongs to the GPI family
FY134_RS00400	COG0318	PFAM AMP-dependent synthetase and ligase
FY134_RS00405	COG3842	ATPase activity
FY134_RS00410	COG1840	ABC-type Fe3 transport system, periplasmic component
FY134_RS00415	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY134_RS00420	COG4774	siderophore transport
FY134_RS00465	COG2326	polyphosphate kinase activity
FY134_RS00475	COG5002	protein histidine kinase activity
FY134_RS00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY134_RS00485	COG0573	inorganic phosphate transmembrane transporter activity
FY134_RS00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY134_RS00500	COG0704	Plays a role in the regulation of phosphate uptake
FY134_RS00505	COG0745	RESPONSE REGULATOR receiver
FY134_RS00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY134_RS00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY134_RS00530	COG2967	ApaG domain
FY134_RS00540	COG0717	Belongs to the dCTP deaminase family
FY134_RS00550	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FY134_RS00570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY134_RS00620	COG0167	dihydroorotate dehydrogenase activity
FY134_RS00635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY134_RS00655	COG1959	2 iron, 2 sulfur cluster binding
FY134_RS00660	COG1201	RNA secondary structure unwinding
FY134_RS00680	COG0730	response to heat
FY134_RS00690	COG1960	acyl-CoA dehydrogenase activity
FY134_RS00695	COG0183	Belongs to the thiolase family
FY134_RS00700	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY134_RS00700	COG1024	Enoyl-CoA hydratase
FY134_RS00720	COG1320	monovalent cation:proton antiporter activity
FY134_RS00725	COG2212	antiporter activity
FY134_RS00730	COG1863	multisubunit Na H antiporter MnhE subunit
FY134_RS00735	COG0651	ATP synthesis coupled electron transport
FY134_RS00740	COG1006	Multisubunit Na H antiporter MnhC subunit
FY134_RS00745	COG2111	Na H antiporter
FY134_RS00745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY134_RS00755	COG0840	transmembrane signaling receptor activity
FY134_RS00765	COG0745	RESPONSE REGULATOR receiver
FY134_RS00770	COG2198	Histidine kinase
FY134_RS00770	COG0643	Histidine kinase
FY134_RS00775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY134_RS00780	COG2201	protein-glutamate methylesterase activity
FY134_RS00785	COG0745	RESPONSE REGULATOR receiver
FY134_RS00790	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY134_RS00800	COG1766	The M ring may be actively involved in energy transduction
FY134_RS00805	COG2771	luxR family
FY134_RS00815	COG0840	transmembrane signaling receptor activity
FY134_RS00815	COG2972	Histidine kinase
FY134_RS00820	COG0784	Response regulator, receiver
FY134_RS00820	COG2198	Histidine kinase
FY134_RS00820	COG2205	protein histidine kinase activity
FY134_RS00830	COG1970	mechanosensitive ion channel activity
FY134_RS00835	COG0436	Aminotransferase
FY134_RS00850	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY134_RS00855	COG0424	maF-like protein
FY134_RS00860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY134_RS00870	COG5328	Belongs to the UPF0262 family
FY134_RS00875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY134_RS00885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY134_RS00920	COG1338	Plays a role in the flagellum-specific transport system
FY134_RS00930	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY134_RS00940	COG1706	bacterial-type flagellum-dependent cell motility
FY134_RS00945	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY134_RS00950	COG4786	Flagellar basal body rod
FY134_RS00955	COG1677	Flagellar hook-basal body complex protein FliE
FY134_RS00960	COG1558	bacterial-type flagellum-dependent cell motility
FY134_RS00965	COG1815	bacterial-type flagellum-dependent cell motility
FY134_RS00970	COG1280	lysine exporter protein (LysE YggA)
FY134_RS00980	COG1157	protein secretion by the type III secretion system
FY134_RS00985	COG4786	Flagellar basal body rod
FY134_RS00995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY134_RS01000	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY134_RS01005	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY134_RS01010	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY134_RS01015	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY134_RS01035	COG1360	Flagellar Motor Protein
FY134_RS01060	COG1749	Flagellar hook protein flgE
FY134_RS01080	COG5443	negative regulation of bacterial-type flagellum assembly
FY134_RS01085	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY134_RS01095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY134_RS01135	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY134_RS01140	COG1609	Transcriptional regulator
FY134_RS01145	COG1653	transport
FY134_RS01150	COG1175	transmembrane transport
FY134_RS01155	COG0395	ABC-type sugar transport system, permease component
FY134_RS01160	COG0366	Alpha amylase catalytic
FY134_RS01165	COG3842	ATPase activity
FY134_RS01175	COG3609	addiction module antidote protein, CC2985 family
FY134_RS01190	COG0129	dihydroxy-acid dehydratase activity
FY134_RS01195	COG0363	glucosamine-6-phosphate deaminase activity
FY134_RS01200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY134_RS01205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS01215	COG2081	HI0933 family
FY134_RS01235	COG2224	Isocitrate lyase
FY134_RS01250	COG3842	ATPase activity
FY134_RS01255	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY134_RS01260	COG1177	transmembrane transport
FY134_RS01270	COG2205	protein histidine kinase activity
FY134_RS01280	COG0248	Ppx GppA phosphatase
FY134_RS01285	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY134_RS01290	COG0477	Major facilitator Superfamily
FY134_RS01335	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY134_RS01340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY134_RS01350	COG0142	geranyltranstransferase activity
FY134_RS01375	COG0752	glycyl-tRNA synthetase alpha subunit
FY134_RS01385	COG1704	LemA family
FY134_RS01390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY134_RS01400	COG0751	glycine-tRNA ligase activity
FY134_RS01405	COG1683	Conserved Protein
FY134_RS01410	COG0840	transmembrane signaling receptor activity
FY134_RS01420	COG0151	Belongs to the GarS family
FY134_RS01425	COG2183	response to ionizing radiation
FY134_RS01430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY134_RS01440	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FY134_RS01455	COG0583	DNA-binding transcription factor activity
FY134_RS01475	COG0306	phosphate transporter
FY134_RS01485	COG0561	phosphatase activity
FY134_RS01490	COG0438	transferase activity, transferring glycosyl groups
FY134_RS01495	COG2186	Transcriptional regulator
FY134_RS01505	COG0583	DNA-binding transcription factor activity
FY134_RS01510	COG0277	FAD linked oxidase domain protein
FY134_RS01515	COG0277	FAD linked oxidase domain protein
FY134_RS01520	COG0247	lactate metabolic process
FY134_RS01530	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_RS01535	COG0519	Catalyzes the synthesis of GMP from XMP
FY134_RS01545	COG2855	membrane
FY134_RS01550	COG0583	DNA-binding transcription factor activity
FY134_RS01570	COG0124	histidyl-tRNA synthetase
FY134_RS01580	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY134_RS01585	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY134_RS01590	COG2259	Doxx family
FY134_RS01600	COG0459	protein refolding
FY134_RS01605	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY134_RS01615	COG0196	riboflavin kinase activity
FY134_RS01620	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY134_RS01630	COG0590	tRNA wobble adenosine to inosine editing
FY134_RS01635	COG1187	pseudouridine synthase activity
FY134_RS01640	COG0742	ribosomal rna small subunit methyltransferase
FY134_RS01645	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY134_RS01655	COG0312	modulator of DNA gyrase
FY134_RS01660	COG0483	inositol monophosphate 1-phosphatase activity
FY134_RS01670	COG1519	Transferase
FY134_RS01680	COG1663	tetraacyldisaccharide 4'-kinase activity
FY134_RS01690	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY134_RS01700	COG3300	MHYT domain
FY134_RS01700	COG5001	Diguanylate cyclase
FY134_RS01705	COG3386	PFAM SMP-30 Gluconolaconase
FY134_RS01710	COG0800	Aldolase
FY134_RS01715	COG3734	2-keto-3-deoxy-galactonokinase
FY134_RS01720	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS01730	COG2197	response regulator
FY134_RS01735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_RS01745	COG0598	Magnesium transport protein CorA
FY134_RS01750	COG3158	transport of potassium into the cell
FY134_RS01765	COG0356	it plays a direct role in the translocation of protons across the membrane
FY134_RS01775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY134_RS01780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY134_RS01795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY134_RS01815	COG0009	L-threonylcarbamoyladenylate synthase
FY134_RS01825	COG4638	Rieske (2fe-2S)
FY134_RS01850	COG1960	acyl-CoA dehydrogenase activity
FY134_RS01865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY134_RS01870	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY134_RS01875	COG0840	transmembrane signaling receptor activity
FY134_RS01885	COG1522	sequence-specific DNA binding
FY134_RS01915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY134_RS01920	COG1741	Belongs to the pirin family
FY134_RS01925	COG1722	exodeoxyribonuclease VII activity
FY134_RS01930	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY134_RS01935	COG1268	BioY protein
FY134_RS01940	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY134_RS01945	COG1122	ATPase activity
FY134_RS01950	COG3214	Protein conserved in bacteria
FY134_RS01955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY134_RS01955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY134_RS01960	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY134_RS01975	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY134_RS01990	COG0259	pyridoxamine-phosphate oxidase activity
FY134_RS02005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY134_RS02015	COG0312	modulator of DNA gyrase
FY134_RS02030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY134_RS02035	COG0109	protoheme IX farnesyltransferase activity
FY134_RS02045	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY134_RS02060	COG3346	SURF1 family
FY134_RS02065	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY134_RS02070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY134_RS02075	COG0328	RNA-DNA hybrid ribonuclease activity
FY134_RS02090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY134_RS02090	COG0678	peroxiredoxin activity
FY134_RS02100	COG1678	Uncharacterized ACR, COG1678
FY134_RS02120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY134_RS02125	COG0612	Peptidase, M16
FY134_RS02150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY134_RS02155	COG1802	Transcriptional regulator
FY134_RS02170	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY134_RS02180	COG1194	a g-specific adenine glycosylase
FY134_RS02190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY134_RS02195	COG1196	nuclear chromosome segregation
FY134_RS02200	COG2514	catechol 2,3-dioxygenase activity
FY134_RS02205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY134_RS02205	COG0574	Belongs to the PEP-utilizing enzyme family
FY134_RS02220	COG1823	symporter activity
FY134_RS02240	COG1309	transcriptional regulator
FY134_RS02250	COG0579	oxidoreductase
FY134_RS02265	COG2895	sulfate adenylyltransferase (ATP) activity
FY134_RS02270	COG0175	sulfate reduction
FY134_RS02275	COG0175	sulfate reduction
FY134_RS02280	COG1959	2 iron, 2 sulfur cluster binding
FY134_RS02285	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY134_RS02290	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY134_RS02295	COG4208	sulfate ABC transporter
FY134_RS02300	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY134_RS02310	COG2203	Gaf domain
FY134_RS02310	COG2199	diguanylate cyclase activity
FY134_RS02310	COG2200	EAL domain
FY134_RS02320	COG1309	transcriptional regulator
FY134_RS02325	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS02330	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY134_RS02365	COG0625	glutathione transferase activity
FY134_RS02375	COG0477	Major facilitator Superfamily
FY134_RS02385	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY134_RS02385	COG1793	dna ligase
FY134_RS02405	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_RS02410	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_RS02415	COG1846	Transcriptional regulator
FY134_RS02420	COG1764	response to oxidative stress
FY134_RS02435	COG0488	(ABC) transporter
FY134_RS02470	COG4221	oxidoreductase activity
FY134_RS02485	COG0433	COG0433 Predicted ATPase
FY134_RS02495	COG1733	regulation of RNA biosynthetic process
FY134_RS02500	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY134_RS02515	COG0656	L-ascorbic acid biosynthetic process
FY134_RS02520	COG2378	regulation of single-species biofilm formation
FY134_RS02530	COG4106	trans-aconitate 2-methyltransferase activity
FY134_RS02535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY134_RS02540	COG0840	transmembrane signaling receptor activity
FY134_RS02545	COG0583	DNA-binding transcription factor activity
FY134_RS02560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY134_RS02570	COG2378	regulation of single-species biofilm formation
FY134_RS02580	COG3909	cytochrome
FY134_RS02585	COG2010	Cytochrome c
FY134_RS02620	COG0789	Transcriptional regulator
FY134_RS02645	COG4175	Glycine betaine
FY134_RS02645	COG0517	IMP dehydrogenase activity
FY134_RS02650	COG4176	ABC-type proline glycine betaine transport system permease component
FY134_RS02670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_RS02680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY134_RS02680	COG2169	Transcriptional regulator
FY134_RS02690	COG2514	catechol 2,3-dioxygenase activity
FY134_RS02710	COG1272	protein, Hemolysin III
FY134_RS02720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY134_RS02725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY134_RS02725	COG2111	Na H antiporter
FY134_RS02730	COG2111	Na H antiporter
FY134_RS02735	COG1006	Multisubunit Na H antiporter MnhC subunit
FY134_RS02740	COG0651	ATP synthesis coupled electron transport
FY134_RS02745	COG1863	multisubunit Na H antiporter MnhE subunit
FY134_RS02750	COG2212	antiporter activity
FY134_RS02755	COG1320	monovalent cation:proton antiporter activity
FY134_RS02760	COG4957	zinc ion binding
FY134_RS02775	COG2166	iron-sulfur cluster assembly
FY134_RS02785	COG2205	protein histidine kinase activity
FY134_RS02825	COG0583	DNA-binding transcription factor activity
FY134_RS02845	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY134_RS02850	COG2983	Belongs to the UPF0260 family
FY134_RS02865	COG2217	Heavy metal translocating P-type atpase
FY134_RS02905	COG1621	beta-fructofuranosidase activity
FY134_RS02910	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY134_RS02960	COG4695	Portal protein
FY134_RS03180	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY134_RS03280	COG4235	cytochrome complex assembly
FY134_RS03285	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY134_RS03290	COG1138	Cytochrome C-type biogenesis protein
FY134_RS03295	COG3088	subunit of a heme lyase
FY134_RS03300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY134_RS03315	COG3011	Protein conserved in bacteria
FY134_RS03325	COG3713	MltA-interacting MipA family protein
FY134_RS03330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY134_RS03335	COG2205	protein histidine kinase activity
FY134_RS03335	COG2202	Pas domain
FY134_RS03345	COG0308	aminopeptidase N
FY134_RS03350	COG0697	spore germination
FY134_RS03365	COG0443	Heat shock 70 kDa protein
FY134_RS03405	COG0604	alcohol dehydrogenase
FY134_RS03410	COG1733	regulation of RNA biosynthetic process
FY134_RS03415	COG1968	undecaprenyl-diphosphatase activity
FY134_RS03420	COG2239	Acts as a magnesium transporter
FY134_RS03425	COG2814	Major facilitator Superfamily
FY134_RS03455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY134_RS03485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY134_RS03535	COG0741	lytic transglycosylase activity
FY134_RS03540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_RS03545	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY134_RS03550	COG0840	transmembrane signaling receptor activity
FY134_RS03560	COG1758	RNA polymerase activity
FY134_RS03580	COG0736	holo-[acyl-carrier-protein] synthase activity
FY134_RS03585	COG0681	Belongs to the peptidase S26 family
FY134_RS03590	COG0571	ribonuclease III activity
FY134_RS03595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY134_RS03600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY134_RS03605	COG0784	Response regulator, receiver
FY134_RS03610	COG1381	Involved in DNA repair and RecF pathway recombination
FY134_RS03620	COG2226	methyltransferase
FY134_RS03630	COG1418	mRNA catabolic process
FY134_RS03640	COG0346	lactoylglutathione lyase activity
FY134_RS03655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_RS03660	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY134_RS03665	COG0668	transmembrane transport
FY134_RS03675	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY134_RS03700	COG1051	belongs to the nudix hydrolase family
FY134_RS03705	COG1742	UPF0060 membrane protein
FY134_RS03725	COG1183	phosphatidylcholine synthase activity
FY134_RS03730	COG0688	phosphatidylethanolamine metabolic process
FY134_RS03735	COG5265	(ABC) transporter
FY134_RS03775	COG2852	Protein conserved in bacteria
FY134_RS03780	COG0215	cysteine-tRNA ligase activity
FY134_RS03785	COG4221	oxidoreductase activity
FY134_RS03790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY134_RS03795	COG1286	toxin biosynthetic process
FY134_RS03815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY134_RS03825	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY134_RS03835	COG0305	Participates in initiation and elongation during chromosome replication
FY134_RS03855	COG0359	binds to the 23S rRNA
FY134_RS03865	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY134_RS03870	COG0360	Binds together with S18 to 16S ribosomal RNA
FY134_RS03875	COG0667	Aldo Keto reductase
FY134_RS03880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY134_RS03890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY134_RS03895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY134_RS03900	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY134_RS03905	COG1561	YicC-like family, N-terminal region
FY134_RS03910	COG0194	GDP metabolic process
FY134_RS03915	COG0400	carboxylic ester hydrolase activity
FY134_RS03920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY134_RS03925	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY134_RS03935	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY134_RS03950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY134_RS03970	COG5001	Diguanylate cyclase
FY134_RS03970	COG3300	MHYT domain
FY134_RS03975	COG4191	Histidine kinase
FY134_RS03990	COG0488	(ABC) transporter
FY134_RS03995	COG3706	GGDEF domain
FY134_RS04005	COG0105	UTP biosynthetic process
FY134_RS04025	COG0314	molybdopterin synthase activity
FY134_RS04030	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FY134_RS04035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY134_RS04040	COG0322	excinuclease ABC activity
FY134_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS04055	COG0625	glutathione transferase activity
FY134_RS04075	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY134_RS04080	COG0243	molybdopterin cofactor binding
FY134_RS04095	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY134_RS04100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY134_RS04105	COG0628	permease
FY134_RS04115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY134_RS04120	COG0248	Ppx GppA phosphatase
FY134_RS04145	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY134_RS04155	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY134_RS04160	COG0477	Major facilitator Superfamily
FY134_RS04165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY134_RS04175	COG4452	Inner membrane protein CreD
FY134_RS04180	COG0659	secondary active sulfate transmembrane transporter activity
FY134_RS04190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY134_RS04195	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY134_RS04205	COG0113	porphobilinogen synthase activity
FY134_RS04225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY134_RS04230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY134_RS04235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY134_RS04235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY134_RS04245	COG1280	lysine exporter protein (LysE YggA)
FY134_RS04250	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY134_RS04255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY134_RS04260	COG2814	Major facilitator Superfamily
FY134_RS04265	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY134_RS04285	COG0416	fatty acid biosynthetic process
FY134_RS04290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY134_RS04295	COG0776	regulation of translation
FY134_RS04330	COG0601	transmembrane transport
FY134_RS04335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS04340	COG0444	Belongs to the ABC transporter superfamily
FY134_RS04350	COG0747	negative chemotaxis
FY134_RS04360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY134_RS04365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY134_RS04380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY134_RS04385	COG0583	DNA-binding transcription factor activity
FY134_RS04390	COG0737	Belongs to the 5'-nucleotidase family
FY134_RS04415	COG2897	thiosulfate sulfurtransferase activity
FY134_RS04430	COG0415	Belongs to the DNA photolyase family
FY134_RS04440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY134_RS04470	COG3932	Exopolysaccharide synthesis, ExoD
FY134_RS04575	COG4626	Terminase
FY134_RS04575	COG1802	Transcriptional regulator
FY134_RS04650	COG0297	glycogen (starch) synthase activity
FY134_RS04675	COG1612	heme a metabolic process
FY134_RS04685	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY134_RS04690	COG0010	Belongs to the arginase family
FY134_RS04695	COG1396	sequence-specific DNA binding
FY134_RS04700	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FY134_RS04705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY134_RS04710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY134_RS04720	COG1832	CoA-binding protein
FY134_RS04750	COG2124	cytochrome p450
FY134_RS04755	COG2199	diguanylate cyclase activity
FY134_RS04760	COG0740	serine-type endopeptidase activity
FY134_RS04765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY134_RS04770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY134_RS04780	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY134_RS04815	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY134_RS04820	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY134_RS04825	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY134_RS04835	COG0649	NAD binding
FY134_RS04845	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY134_RS04850	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY134_RS04860	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY134_RS04865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY134_RS04875	COG0713	ATP synthesis coupled electron transport
FY134_RS04890	COG1007	ATP synthesis coupled electron transport
FY134_RS04895	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY134_RS04895	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY134_RS04910	COG0442	prolyl-tRNA aminoacylation
FY134_RS04920	COG1136	(ABC) transporter
FY134_RS04935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY134_RS04955	COG0784	Response regulator, receiver
FY134_RS04965	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY134_RS04970	COG0477	Major facilitator Superfamily
FY134_RS04985	COG0557	exoribonuclease II activity
FY134_RS04990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY134_RS05000	COG0758	DNA mediated transformation
FY134_RS05005	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY134_RS05015	COG0540	Belongs to the ATCase OTCase family
FY134_RS05025	COG1960	acyl-CoA dehydrogenase activity
FY134_RS05030	COG0456	acetyltransferase
FY134_RS05060	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY134_RS05065	COG2824	Alkylphosphonate utilization operon protein PhnA
FY134_RS05070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY134_RS05075	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY134_RS05080	COG0154	amidase activity
FY134_RS05085	COG3811	Belongs to the UPF0386 family
FY134_RS05100	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY134_RS05110	COG0456	acetyltransferase
FY134_RS05125	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY134_RS05130	COG0439	Biotin carboxylase
FY134_RS05135	COG0511	ligase activity, forming carbon-carbon bonds
FY134_RS05140	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY134_RS05150	COG0436	Aminotransferase
FY134_RS05170	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS05175	COG1530	ribonuclease E activity
FY134_RS05185	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY134_RS05205	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY134_RS05210	COG0384	phenazine biosynthesis protein PhzF
FY134_RS05225	COG0633	Ferredoxin
FY134_RS05235	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FY134_RS05240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY134_RS05245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY134_RS05255	COG3768	UPF0283 membrane protein
FY134_RS05260	COG3106	COG3106 Predicted ATPase
FY134_RS05290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY134_RS05320	COG0537	adenosine 5'-monophosphoramidase activity
FY134_RS05345	COG0052	Belongs to the universal ribosomal protein uS2 family
FY134_RS05350	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY134_RS05355	COG0528	UMP kinase activity
FY134_RS05360	COG0233	cytoplasmic translational termination
FY134_RS05365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY134_RS05375	COG0750	zinc metalloprotease
FY134_RS05380	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY134_RS05385	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY134_RS05390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY134_RS05395	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY134_RS05400	COG3494	Protein of unknown function (DUF1009)
FY134_RS05405	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY134_RS05410	COG2186	Transcriptional regulator
FY134_RS05420	COG0765	amino acid transport
FY134_RS05425	COG0765	amino acid transport
FY134_RS05435	COG0372	Belongs to the citrate synthase family
FY134_RS05450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY134_RS05455	COG4598	ABC transporter
FY134_RS05460	COG0765	amino acid transport
FY134_RS05465	COG0765	amino acid transport
FY134_RS05470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS05475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_RS05480	COG3842	ATPase activity
FY134_RS05485	COG0395	ABC-type sugar transport system, permease component
FY134_RS05495	COG2182	Extracellular solute-binding protein
FY134_RS05505	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_RS05510	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS05515	COG1063	alcohol dehydrogenase
FY134_RS05520	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY134_RS05540	COG0683	leucine binding
FY134_RS05545	COG1960	acyl-CoA dehydrogenase activity
FY134_RS05560	COG1024	Enoyl-CoA hydratase
FY134_RS05575	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_RS05595	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY134_RS05600	COG0148	phosphopyruvate hydratase activity
FY134_RS05610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY134_RS05615	COG0022	dehydrogenase e1 component
FY134_RS05615	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY134_RS05625	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY134_RS05635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY134_RS05645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY134_RS05650	COG0697	spore germination
FY134_RS05670	COG2867	negative regulation of translational initiation
FY134_RS05675	COG1546	Belongs to the CinA family
FY134_RS05680	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY134_RS05680	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY134_RS05690	COG3852	Histidine kinase
FY134_RS05695	COG2204	response regulator
FY134_RS05700	COG5000	phosphorelay sensor kinase activity
FY134_RS05705	COG2204	response regulator
FY134_RS05715	COG1923	regulation of RNA biosynthetic process
FY134_RS05720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY134_RS05725	COG3956	TIGRFAM MazG family protein
FY134_RS05740	COG1648	precorrin-2 dehydrogenase activity
FY134_RS05740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY134_RS05755	COG0275	rRNA processing
FY134_RS05780	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY134_RS05780	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY134_RS05785	COG0509	glycine decarboxylation via glycine cleavage system
FY134_RS05790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_RS05815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY134_RS05840	COG0251	oxidation-reduction process
FY134_RS05845	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY134_RS05855	COG1671	Belongs to the UPF0178 family
FY134_RS05865	COG0450	alkyl hydroperoxide reductase
FY134_RS05905	COG2826	transposase and inactivated derivatives, IS30 family
FY134_RS05910	COG0431	NADPH-dependent FMN reductase
FY134_RS05920	COG0798	PFAM Bile acid sodium symporter
FY134_RS05940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY134_RS05940	COG0321	lipoyl(octanoyl) transferase activity
FY134_RS05945	COG0084	hydrolase, TatD family'
FY134_RS05950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY134_RS05960	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY134_RS06015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY134_RS06020	COG2095	MarC family integral membrane protein
FY134_RS06025	COG0617	tRNA 3'-terminal CCA addition
FY134_RS06025	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY134_RS06025	COG0517	IMP dehydrogenase activity
FY134_RS06035	COG3609	addiction module antidote protein, CC2985 family
FY134_RS06040	COG0629	single-stranded DNA binding
FY134_RS06045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY134_RS06055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY134_RS06060	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY134_RS06075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY134_RS06080	COG1121	(ABC) transporter
FY134_RS06100	COG0667	Aldo Keto reductase
FY134_RS06110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY134_RS06180	COG0668	transmembrane transport
FY134_RS06205	COG2239	Acts as a magnesium transporter
FY134_RS06210	COG0243	molybdopterin cofactor binding
FY134_RS06220	COG0242	peptide deformylase activity
FY134_RS06245	COG0321	lipoyl(octanoyl) transferase activity
FY134_RS06250	COG1064	alcohol dehydrogenase
FY134_RS06280	COG1862	Preprotein translocase
FY134_RS06305	COG2124	cytochrome p450
FY134_RS06325	COG0596	Alpha beta hydrolase
FY134_RS06335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY134_RS06340	COG0626	cystathionine gamma-synthase activity
FY134_RS06345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS06350	COG4597	amino acid ABC transporter
FY134_RS06355	COG0765	amino acid transport
FY134_RS06360	COG1126	abc transporter atp-binding protein
FY134_RS06375	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY134_RS06390	COG0436	Aminotransferase
FY134_RS06420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY134_RS06430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY134_RS06435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY134_RS06440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY134_RS06455	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY134_RS06460	COG1489	DNA binding
FY134_RS06465	COG0024	Methionine aminopeptidase
FY134_RS06470	COG2003	Belongs to the UPF0758 family
FY134_RS06485	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY134_RS06505	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY134_RS06510	COG0546	phosphoglycolate phosphatase activity
FY134_RS06525	COG0114	fumarate hydratase activity
FY134_RS06535	COG0504	CTP synthase activity
FY134_RS06545	COG0149	triose-phosphate isomerase activity
FY134_RS06555	COG0187	DNA topoisomerase II activity
FY134_RS06565	COG1309	transcriptional regulator
FY134_RS06570	COG2226	methyltransferase
FY134_RS06580	COG0740	serine-type endopeptidase activity
FY134_RS06590	COG0640	Transcriptional regulator
FY134_RS06595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY134_RS06600	COG0745	RESPONSE REGULATOR receiver
FY134_RS06610	COG3264	Mechanosensitive ion channel
FY134_RS06610	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY134_RS06675	COG1127	ABC transporter
FY134_RS06680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY134_RS06685	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_RS06700	COG0281	malic enzyme
FY134_RS06700	COG0280	phosphate acetyltransferase
FY134_RS06710	COG0778	Nitroreductase
FY134_RS06715	COG0823	Involved in the tonB-independent uptake of proteins
FY134_RS06725	COG1368	sulfuric ester hydrolase activity
FY134_RS06750	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY134_RS06770	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY134_RS06775	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY134_RS06810	COG0343	queuine tRNA-ribosyltransferase activity
FY134_RS06815	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY134_RS06830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY134_RS06850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY134_RS06855	COG0134	indole-3-glycerol-phosphate synthase activity
FY134_RS06860	COG0315	cyclic pyranopterin monophosphate synthase activity
FY134_RS06865	COG0303	'Molybdopterin
FY134_RS06870	COG3706	GGDEF domain
FY134_RS06880	COG0475	glutathione-regulated potassium exporter activity
FY134_RS06880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY134_RS06890	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY134_RS06895	COG0697	spore germination
FY134_RS06900	COG2814	Major facilitator Superfamily
FY134_RS06905	COG0746	molybdenum cofactor guanylyltransferase activity
FY134_RS06910	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY134_RS06915	COG0739	heme binding
FY134_RS06920	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY134_RS06925	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY134_RS06930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY134_RS06935	COG0805	protein transport
FY134_RS06940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY134_RS06945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY134_RS06950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY134_RS06955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY134_RS06960	COG1472	Belongs to the glycosyl hydrolase 3 family
FY134_RS06970	COG0018	arginyl-trna synthetase
FY134_RS06975	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY134_RS06980	COG0316	Belongs to the HesB IscA family
FY134_RS06990	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FY134_RS07005	COG0525	valine-tRNA ligase activity
FY134_RS07015	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY134_RS07045	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY134_RS07050	COG1058	Belongs to the CinA family
FY134_RS07050	COG1546	Belongs to the CinA family
FY134_RS07055	COG0589	response to stress
FY134_RS07060	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY134_RS07065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY134_RS07125	COG0084	hydrolase, TatD family'
FY134_RS07155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY134_RS07175	COG1914	H( )-stimulated, divalent metal cation uptake system
FY134_RS07185	COG1132	(ABC) transporter
FY134_RS07190	COG0628	permease
FY134_RS07210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY134_RS07225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY134_RS07235	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY134_RS07245	COG0302	gtp cyclohydrolase
FY134_RS07250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY134_RS07255	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY134_RS07260	COG0516	GMP reductase activity
FY134_RS07260	COG0517	IMP dehydrogenase activity
FY134_RS07290	COG1760	l-serine dehydratase
FY134_RS07325	COG0583	DNA-binding transcription factor activity
FY134_RS07335	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY134_RS07335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY134_RS07345	COG0347	Belongs to the P(II) protein family
FY134_RS07350	COG0174	glutamine synthetase
FY134_RS07380	COG0697	spore germination
FY134_RS07390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY134_RS07400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY134_RS07430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY134_RS07435	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY134_RS07440	COG2186	Transcriptional regulator
FY134_RS07450	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY134_RS07455	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY134_RS07460	COG3845	ABC transporter
FY134_RS07465	COG1183	phosphatidylcholine synthase activity
FY134_RS07470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY134_RS07475	COG0679	Auxin Efflux Carrier
FY134_RS07480	COG0785	Cytochrome C biogenesis protein
FY134_RS07510	COG1278	Cold shock
FY134_RS07560	COG2267	carboxylic ester hydrolase activity
FY134_RS07575	COG1136	(ABC) transporter
FY134_RS07575	COG0577	efflux transmembrane transporter activity
FY134_RS07580	COG1136	(ABC) transporter
FY134_RS07580	COG0577	efflux transmembrane transporter activity
FY134_RS07595	COG2151	metal-sulfur cluster biosynthetic enzyme
FY134_RS07600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY134_RS07605	COG0719	Fe-S assembly protein
FY134_RS07610	COG0396	ATPase activity
FY134_RS07620	COG0719	Fe-S assembly protein
FY134_RS07625	COG1104	cysteine desulfurase activity
FY134_RS07630	COG2945	thiolester hydrolase activity
FY134_RS07640	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY134_RS07645	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY134_RS07655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY134_RS07660	COG2833	Protein of unknown function (DUF455)
FY134_RS07665	COG0739	heme binding
FY134_RS07670	COG0513	Belongs to the DEAD box helicase family
FY134_RS07700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY134_RS07710	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY134_RS07715	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY134_RS07720	COG0047	phosphoribosylformylglycinamidine synthase activity
FY134_RS07735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY134_RS07745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY134_RS07765	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY134_RS07770	COG2814	Major facilitator Superfamily
FY134_RS07775	COG0483	inositol monophosphate 1-phosphatase activity
FY134_RS07780	COG0483	inositol monophosphate 1-phosphatase activity
FY134_RS07785	COG0037	tRNA processing
FY134_RS07790	COG2066	Belongs to the glutaminase family
FY134_RS07795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY134_RS07800	COG0861	Integral membrane protein TerC family
FY134_RS07815	COG1280	lysine exporter protein (LysE YggA)
FY134_RS07825	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY134_RS07830	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY134_RS07840	COG0538	isocitrate dehydrogenase activity
FY134_RS07855	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY134_RS07860	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY134_RS07865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_RS07870	COG2313	pseudouridylate synthase activity
FY134_RS07880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS07885	COG4215	(ABC) transporter
FY134_RS07895	COG5425	PFAM Usg family protein
FY134_RS07905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_RS07910	COG1522	sequence-specific DNA binding
FY134_RS07915	COG1573	uracil-dna glycosylase
FY134_RS07925	COG2205	protein histidine kinase activity
FY134_RS07925	COG2202	Pas domain
FY134_RS07935	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY134_RS07940	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY134_RS07955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY134_RS07960	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS07965	COG1129	ABC transporter
FY134_RS07975	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS07980	COG3959	Transketolase, thiamine diphosphate binding domain
FY134_RS07985	COG3958	Transketolase
FY134_RS07990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY134_RS07995	COG2390	Transcriptional regulator
FY134_RS08005	COG0842	Transport permease protein
FY134_RS08010	COG1131	(ABC) transporter
FY134_RS08040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY134_RS08045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY134_RS08060	COG0129	dihydroxy-acid dehydratase activity
FY134_RS08065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY134_RS08070	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY134_RS08080	COG0203	ribosomal protein L17
FY134_RS08085	COG0202	RNA polymerase activity
FY134_RS08090	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY134_RS08095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY134_RS08100	COG0563	adenylate kinase activity
FY134_RS08105	COG0201	protein transport
FY134_RS08110	COG0200	Binds to the 23S rRNA
FY134_RS08115	COG1841	ribosomal large subunit assembly
FY134_RS08120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY134_RS08125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY134_RS08130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY134_RS08135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY134_RS08140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY134_RS08145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY134_RS08150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY134_RS08155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY134_RS08160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY134_RS08165	COG0255	Belongs to the universal ribosomal protein uL29 family
FY134_RS08170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY134_RS08175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY134_RS08180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY134_RS08185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY134_RS08190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY134_RS08195	COG0089	rRNA binding
FY134_RS08200	COG0088	Forms part of the polypeptide exit tunnel
FY134_RS08205	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY134_RS08210	COG0051	transcription antitermination factor activity, RNA binding
FY134_RS08215	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY134_RS08220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY134_RS08225	COG0049	tRNA binding
FY134_RS08230	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY134_RS08250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY134_RS08255	COG0085	RNA polymerase activity
FY134_RS08260	COG0222	ribosome binding
FY134_RS08265	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY134_RS08270	COG0081	regulation of translation
FY134_RS08275	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY134_RS08285	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY134_RS08295	COG1086	Polysaccharide biosynthesis protein
FY134_RS08300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY134_RS08305	COG0861	Integral membrane protein TerC family
FY134_RS08310	COG3895	Periplasmic Protein
FY134_RS08330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY134_RS08350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY134_RS08385	COG0784	Response regulator, receiver
FY134_RS08385	COG2205	protein histidine kinase activity
FY134_RS08385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS08385	COG2198	Histidine kinase
FY134_RS08390	COG0784	Response regulator, receiver
FY134_RS08395	COG2202	Pas domain
FY134_RS08395	COG3920	Histidine kinase
FY134_RS08400	COG0784	Response regulator, receiver
FY134_RS08405	COG4251	negative regulation of phosphorylation
FY134_RS08420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY134_RS08450	COG2910	NAD(P)H-binding
FY134_RS08455	COG1733	regulation of RNA biosynthetic process
FY134_RS08460	COG0556	nucleotide-excision repair
FY134_RS08465	COG2382	esterase
FY134_RS08485	COG0484	heat shock protein binding
FY134_RS08500	COG3706	GGDEF domain
FY134_RS08510	COG3842	ATPase activity
FY134_RS08520	COG1840	ABC-type Fe3 transport system, periplasmic component
FY134_RS08525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY134_RS08535	COG4115	mRNA cleavage
FY134_RS08545	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY134_RS08555	COG2207	Transcriptional regulator
FY134_RS08560	COG1064	alcohol dehydrogenase
FY134_RS08565	COG1252	NADH dehydrogenase
FY134_RS08570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY134_RS08575	COG2197	response regulator
FY134_RS08580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY134_RS08610	COG0656	L-ascorbic acid biosynthetic process
FY134_RS08625	COG0440	acetolactate synthase activity
FY134_RS08630	COG0028	Belongs to the TPP enzyme family
FY134_RS08640	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY134_RS08645	COG0560	Phosphoserine phosphatase
FY134_RS08645	COG3830	Belongs to the UPF0237 family
FY134_RS08655	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS08665	COG0330	HflC and HflK could
FY134_RS08670	COG0330	HflC and HflK could
FY134_RS08680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY134_RS08715	COG0277	FAD linked oxidase domain protein
FY134_RS08720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY134_RS08775	COG1335	isochorismatase
FY134_RS08795	COG0006	proline dipeptidase activity
FY134_RS08805	COG2264	protein methyltransferase activity
FY134_RS08810	COG1999	signal sequence binding
FY134_RS08820	COG0835	chemotaxis
FY134_RS08835	COG0583	DNA-binding transcription factor activity
FY134_RS08845	COG1247	-acetyltransferase
FY134_RS08855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY134_RS08860	COG0497	DNA recombination
FY134_RS08865	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY134_RS08875	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY134_RS08880	COG0849	cell division
FY134_RS08885	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY134_RS08890	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY134_RS08895	COG0477	Major facilitator Superfamily
FY134_RS08900	COG3300	MHYT domain
FY134_RS08900	COG5001	Diguanylate cyclase
FY134_RS08905	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY134_RS08910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY134_RS08915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY134_RS08925	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY134_RS08930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY134_RS08940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY134_RS08955	COG0275	rRNA processing
FY134_RS08960	COG2001	Belongs to the MraZ family
FY134_RS08985	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY134_RS09015	COG4106	trans-aconitate 2-methyltransferase activity
FY134_RS09035	COG2226	methyltransferase
FY134_RS09045	COG2267	carboxylic ester hydrolase activity
FY134_RS09050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY134_RS09065	COG0251	oxidation-reduction process
FY134_RS09080	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_RS09085	COG2814	Major facilitator Superfamily
FY134_RS09110	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS09125	COG0174	glutamine synthetase
FY134_RS09130	COG0531	amino acid
FY134_RS09140	COG1737	Transcriptional regulator
FY134_RS09160	COG3842	ATPase activity
FY134_RS09225	COG2968	Membrane
FY134_RS09250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY134_RS09255	COG0358	DNA primase activity
FY134_RS09275	COG0505	Belongs to the CarA family
FY134_RS09290	COG0534	Mate efflux family protein
FY134_RS09305	COG2321	neutral zinc metallopeptidase
FY134_RS09320	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY134_RS09325	COG3706	GGDEF domain
FY134_RS09340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY134_RS09350	COG1522	sequence-specific DNA binding
FY134_RS09355	COG0492	ferredoxin-NADP+ reductase activity
FY134_RS09360	COG0583	DNA-binding transcription factor activity
FY134_RS09370	COG1902	pentaerythritol trinitrate reductase activity
FY134_RS09395	COG0387	Pfam Sodium calcium exchanger
FY134_RS09400	COG0436	Aminotransferase
FY134_RS09405	COG2199	diguanylate cyclase activity
FY134_RS09405	COG2200	EAL domain
FY134_RS09420	COG1278	Cold shock
FY134_RS09425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY134_RS09435	COG1846	Transcriptional regulator
FY134_RS09440	COG0745	RESPONSE REGULATOR receiver
FY134_RS09445	COG2205	protein histidine kinase activity
FY134_RS09450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY134_RS09470	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY134_RS09480	COG1496	oxidoreductase activity
FY134_RS09495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY134_RS09505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY134_RS09520	COG0840	transmembrane signaling receptor activity
FY134_RS09525	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS09530	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY134_RS09535	COG5001	Diguanylate cyclase
FY134_RS09535	COG3300	MHYT domain
FY134_RS09540	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY134_RS09545	COG5001	Diguanylate cyclase
FY134_RS09555	COG0193	aminoacyl-tRNA hydrolase activity
FY134_RS09565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY134_RS09585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY134_RS09590	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY134_RS09590	COG2857	Cytochrome c1
FY134_RS09610	COG1132	(ABC) transporter
FY134_RS09615	COG1132	(ABC) transporter
FY134_RS09620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FY134_RS09625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY134_RS09640	COG0408	coproporphyrinogen oxidase activity
FY134_RS09655	COG0617	tRNA 3'-terminal CCA addition
FY134_RS09670	COG0714	Associated with various cellular activities
FY134_RS09690	COG0454	-acetyltransferase
FY134_RS09695	COG0477	Major facilitator Superfamily
FY134_RS09705	COG0435	Glutathione S-transferase
FY134_RS09710	COG0494	nUDIX hydrolase
FY134_RS09720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY134_RS09735	COG3135	benzoate transporter
FY134_RS09750	COG1595	DNA-templated transcription, initiation
FY134_RS09760	COG0740	serine-type endopeptidase activity
FY134_RS09775	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY134_RS09780	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY134_RS09805	COG4175	Glycine betaine
FY134_RS09820	COG1435	thymidine kinase activity
FY134_RS09840	COG2862	Uncharacterized protein family, UPF0114
FY134_RS09845	COG1629	transport
FY134_RS09845	COG4771	TonB-dependent receptor
FY134_RS09855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY134_RS09855	COG0512	Glutamine amidotransferase of anthranilate synthase
FY134_RS09870	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY134_RS09885	COG0366	Alpha amylase catalytic
FY134_RS09890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_RS09915	COG1160	GTP binding
FY134_RS09935	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY134_RS09945	COG0024	Methionine aminopeptidase
FY134_RS09955	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS09965	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY134_RS09975	COG0583	DNA-binding transcription factor activity
FY134_RS09990	COG0402	S-adenosylhomocysteine deaminase activity
FY134_RS10005	COG1304	FMN binding
FY134_RS10015	COG1309	transcriptional regulator
FY134_RS10020	COG1686	Belongs to the peptidase S11 family
FY134_RS10030	COG2351	hydroxyisourate hydrolase activity
FY134_RS10035	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY134_RS10050	COG3195	allantoin biosynthetic process
FY134_RS10050	COG3648	Uricase
FY134_RS10060	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY134_RS10070	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY134_RS10070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS10080	COG0513	Belongs to the DEAD box helicase family
FY134_RS10085	COG0697	spore germination
FY134_RS10090	COG2259	Doxx family
FY134_RS10095	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_RS10105	COG2308	Evidence 4 Homologs of previously reported genes of
FY134_RS10115	COG1305	Transglutaminase-like
FY134_RS10130	COG0456	acetyltransferase
FY134_RS10145	COG4214	carbohydrate transport
FY134_RS10150	COG1129	ABC transporter
FY134_RS10155	COG4213	ABC transporter substrate-binding protein
FY134_RS10280	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY134_RS10290	COG0840	transmembrane signaling receptor activity
FY134_RS10295	COG2814	Major facilitator Superfamily
FY134_RS10300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY134_RS10300	COG0646	methionine synthase
FY134_RS10310	COG4215	(ABC) transporter
FY134_RS10315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS10340	COG1215	transferase activity, transferring glycosyl groups
FY134_RS10370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY134_RS10375	COG2346	COG2346, Truncated hemoglobins
FY134_RS10395	COG1309	transcriptional regulator
FY134_RS10410	COG0494	nUDIX hydrolase
FY134_RS10420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_RS10425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_RS10450	COG1234	tRNA 3'-trailer cleavage
FY134_RS10455	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY134_RS10460	COG0830	nickel cation binding
FY134_RS10465	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY134_RS10480	COG0804	urea catabolic process
FY134_RS10485	COG1442	glycosyl transferase family 8
FY134_RS10490	COG3755	Protein conserved in bacteria
FY134_RS10500	COG0832	Belongs to the urease beta subunit family
FY134_RS10505	COG3813	Protein conserved in bacteria
FY134_RS10510	COG0831	urea catabolic process
FY134_RS10515	COG0829	nickel cation binding
FY134_RS10535	COG0411	ABC transporter
FY134_RS10545	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY134_RS10560	COG0174	glutamine synthetase
FY134_RS10565	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS10570	COG5002	protein histidine kinase activity
FY134_RS10570	COG2198	Histidine kinase
FY134_RS10570	COG0784	Response regulator, receiver
FY134_RS10620	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY134_RS10695	COG0564	pseudouridine synthase activity
FY134_RS10705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY134_RS10715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY134_RS10740	COG0346	lactoylglutathione lyase activity
FY134_RS10750	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY134_RS10760	COG2832	Protein of unknown function (DUF454)
FY134_RS10765	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY134_RS10770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_RS10775	COG4558	Periplasmic binding protein
FY134_RS10785	COG3721	Heme iron utilization protein
FY134_RS10800	COG2205	protein histidine kinase activity
FY134_RS10840	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_RS10845	COG4605	iron ion homeostasis
FY134_RS10850	COG4604	ABC transporter, ATP-binding protein
FY134_RS10855	COG0783	Belongs to the Dps family
FY134_RS10870	COG0583	DNA-binding transcription factor activity
FY134_RS10875	COG0657	acetylesterase activity
FY134_RS10880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_RS10900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY134_RS10905	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY134_RS10910	COG0288	reversible hydration of carbon dioxide
FY134_RS10920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY134_RS10935	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY134_RS10940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY134_RS10945	COG0778	Nitroreductase
FY134_RS10950	COG2267	carboxylic ester hydrolase activity
FY134_RS10955	COG0251	oxidation-reduction process
FY134_RS10960	COG1335	isochorismatase
FY134_RS10965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS10975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_RS10985	COG1653	transport
FY134_RS10990	COG1175	transmembrane transport
FY134_RS10995	COG0395	ABC-type sugar transport system, permease component
FY134_RS11000	COG3842	ATPase activity
FY134_RS11005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_RS11015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY134_RS11030	COG4608	Belongs to the ABC transporter superfamily
FY134_RS11035	COG0444	Belongs to the ABC transporter superfamily
FY134_RS11040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS11045	COG0601	transmembrane transport
FY134_RS11065	COG0392	lysyltransferase activity
FY134_RS11065	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FY134_RS11105	COG2159	amidohydrolase
FY134_RS11110	COG1960	acyl-CoA dehydrogenase activity
FY134_RS11140	COG0745	RESPONSE REGULATOR receiver
FY134_RS11150	COG1902	pentaerythritol trinitrate reductase activity
FY134_RS11150	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY134_RS11185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY134_RS11195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_RS11200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY134_RS11210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY134_RS11220	COG1509	lysine 2,3-aminomutase activity
FY134_RS11235	COG0583	DNA-binding transcription factor activity
FY134_RS11240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS11245	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY134_RS11250	COG4149	molybdate abc transporter
FY134_RS11255	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY134_RS11265	COG3191	aminopeptidase activity
FY134_RS11270	COG2022	thiamine diphosphate biosynthetic process
FY134_RS11285	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY134_RS11290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY134_RS11300	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY134_RS11325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY134_RS11350	COG0438	transferase activity, transferring glycosyl groups
FY134_RS11370	COG4166	transmembrane transport
FY134_RS11380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS11390	COG0438	transferase activity, transferring glycosyl groups
FY134_RS11395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY134_RS11400	COG3142	Participates in the control of copper homeostasis
FY134_RS11420	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS11425	COG1737	Transcriptional regulator
FY134_RS11435	COG3842	ATPase activity
FY134_RS11445	COG0395	ABC-type sugar transport system, permease component
FY134_RS11450	COG1175	transmembrane transport
FY134_RS11460	COG2188	Transcriptional regulator
FY134_RS11465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY134_RS11470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY134_RS11475	COG1940	carbohydrate kinase activity
FY134_RS11485	COG0671	phosphoesterase, PA-phosphatase related
FY134_RS11490	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY134_RS11495	COG0156	8-amino-7-oxononanoate synthase activity
FY134_RS11505	COG0729	surface antigen
FY134_RS11515	COG0835	chemotaxis
FY134_RS11525	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY134_RS11530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY134_RS11535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY134_RS11540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY134_RS11545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY134_RS11550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY134_RS11565	COG4974	Belongs to the 'phage' integrase family
FY134_RS11590	COG1280	lysine exporter protein (LysE YggA)
FY134_RS11600	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY134_RS11610	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY134_RS11615	COG0045	succinate-CoA ligase (ADP-forming) activity
FY134_RS11620	COG0039	L-malate dehydrogenase activity
FY134_RS11625	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY134_RS11660	COG2264	protein methyltransferase activity
FY134_RS11675	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY134_RS11680	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY134_RS11685	COG0181	hydroxymethylbilane synthase activity
FY134_RS11725	COG1872	DUF167
FY134_RS11730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY134_RS11745	COG1217	gtp-binding protein TYPA
FY134_RS11750	COG0339	signal peptide processing
FY134_RS11755	COG1846	Transcriptional regulator
FY134_RS11765	COG0137	argininosuccinate synthase activity
FY134_RS11775	COG1280	lysine exporter protein (LysE YggA)
FY134_RS11780	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY134_RS11785	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY134_RS11795	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY134_RS11810	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY134_RS11815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY134_RS11820	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY134_RS11830	COG4181	ATPase activity
FY134_RS11840	COG0670	Belongs to the BI1 family
FY134_RS11855	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY134_RS11860	COG4133	protoheme IX ABC transporter activity
FY134_RS11865	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY134_RS11870	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY134_RS11895	COG2917	probably involved in intracellular septation
FY134_RS11900	COG0552	protein localization to endoplasmic reticulum
FY134_RS11905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY134_RS11910	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY134_RS11920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY134_RS11925	COG1605	Chorismate mutase
FY134_RS11925	COG0287	Prephenate dehydrogenase
FY134_RS11930	COG0228	four-way junction DNA binding
FY134_RS11935	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY134_RS11940	COG0336	Belongs to the RNA methyltransferase TrmD family
FY134_RS11950	COG0335	large ribosomal subunit rRNA binding
FY134_RS11955	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY134_RS11960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_RS11975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY134_RS11985	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY134_RS12005	COG0488	(ABC) transporter
FY134_RS12015	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY134_RS12025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY134_RS12030	COG0142	geranyltranstransferase activity
FY134_RS12035	COG2885	chlorophyll binding
FY134_RS12040	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY134_RS12045	COG2223	nitrite transmembrane transporter activity
FY134_RS12050	COG1349	DNA-binding transcription factor activity
FY134_RS12055	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY134_RS12060	COG2197	response regulator
FY134_RS12065	COG1132	(ABC) transporter
FY134_RS12075	COG3459	Glycosyltransferase 36 associated
FY134_RS12080	COG1473	amidohydrolase
FY134_RS12090	COG0579	oxidoreductase
FY134_RS12100	COG0129	dihydroxy-acid dehydratase activity
FY134_RS12105	COG2084	Dehydrogenase
FY134_RS12110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_RS12115	COG0277	FAD linked oxidase domain protein
FY134_RS12120	COG2186	Transcriptional regulator
FY134_RS12130	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY134_RS12135	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY134_RS12140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_RS12145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY134_RS12155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY134_RS12160	COG0495	leucyl-tRNA aminoacylation
FY134_RS12175	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY134_RS12190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY134_RS12195	COG1946	Acyl-CoA thioesterase
FY134_RS12200	COG0347	Belongs to the P(II) protein family
FY134_RS12205	COG0004	ammonium transporteR
FY134_RS12210	COG1674	ftsk spoiiie
FY134_RS12215	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY134_RS12230	COG0745	RESPONSE REGULATOR receiver
FY134_RS12240	COG1329	Transcriptional regulator
FY134_RS12245	COG2902	Dehydrogenase
FY134_RS12250	COG2270	Major facilitator Superfamily
FY134_RS12265	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS12280	COG0494	nUDIX hydrolase
FY134_RS12290	COG0793	Belongs to the peptidase S41A family
FY134_RS12300	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY134_RS12305	COG0799	negative regulation of ribosome biogenesis
FY134_RS12310	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY134_RS12315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY134_RS12320	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY134_RS12325	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY134_RS12340	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY134_RS12345	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY134_RS12370	COG0066	3-isopropylmalate dehydratase activity
FY134_RS12375	COG0473	3-isopropylmalate dehydrogenase activity
FY134_RS12380	COG1858	cytochrome C peroxidase
FY134_RS12385	COG1797	cobyrinic acid a,c-diamide synthase activity
FY134_RS12390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY134_RS12390	COG1648	precorrin-2 dehydrogenase activity
FY134_RS12395	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY134_RS12460	COG1492	cobalamin metabolic process
FY134_RS12475	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_RS12480	COG3254	rhamnose metabolic process
FY134_RS12485	COG0246	Mannitol dehydrogenase
FY134_RS12490	COG1063	alcohol dehydrogenase
FY134_RS12510	COG4214	carbohydrate transport
FY134_RS12515	COG1129	ABC transporter
FY134_RS12520	COG2186	Transcriptional regulator
FY134_RS12525	COG2721	sulfolactate sulfo-lyase activity
FY134_RS12530	COG0138	bifunctional purine biosynthesis protein purh
FY134_RS12540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY134_RS12540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY134_RS12545	COG0501	Belongs to the peptidase M48B family
FY134_RS12565	COG0357	Ribosomal RNA small subunit methyltransferase G
FY134_RS12570	COG0445	tRNA wobble uridine modification
FY134_RS12575	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY134_RS12580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY134_RS12585	COG1981	membrane
FY134_RS12590	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY134_RS12595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY134_RS12600	COG0424	maF-like protein
FY134_RS12605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY134_RS12610	COG0237	dephospho-CoA kinase activity
FY134_RS12620	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY134_RS12625	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY134_RS12635	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY134_RS12660	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY134_RS12675	COG0135	phosphoribosylanthranilate isomerase activity
FY134_RS12680	COG0133	tryptophan synthase activity
FY134_RS12685	COG0159	tryptophan synthase activity
FY134_RS12690	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY134_RS12705	COG1074	ATP-dependent DNA helicase activity
FY134_RS12715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY134_RS12725	COG2205	protein histidine kinase activity
FY134_RS12730	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY134_RS12735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY134_RS12740	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY134_RS12740	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY134_RS12745	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY134_RS12750	COG0642	Histidine kinase
FY134_RS12755	COG0745	RESPONSE REGULATOR receiver
FY134_RS12760	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY134_RS12770	COG1072	(Pantothenic acid kinase))
FY134_RS12775	COG0140	phosphoribosyl-ATP diphosphatase activity
FY134_RS12780	COG0107	imidazoleglycerol-phosphate synthase activity
FY134_RS12785	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY134_RS12790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY134_RS12800	COG0131	Imidazoleglycerol-phosphate dehydratase
FY134_RS12805	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY134_RS12810	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY134_RS12820	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY134_RS12835	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY134_RS12845	COG1643	Atp-dependent helicase
FY134_RS12880	COG0514	ATP-dependent DNA helicase (RecQ)
FY134_RS12905	COG1072	(Pantothenic acid kinase))
FY134_RS12915	COG1780	Probably involved in ribonucleotide reductase function
FY134_RS12935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY134_RS12965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_RS12975	COG2813	Specifically methylates the guanine in position
FY134_RS12980	COG1185	polyribonucleotide nucleotidyltransferase activity
FY134_RS12985	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY134_RS12990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY134_RS12995	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY134_RS13000	COG3064	Membrane
FY134_RS13000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY134_RS13015	COG0779	Required for maturation of 30S ribosomal subunits
FY134_RS13020	COG2814	Major facilitator Superfamily
FY134_RS13025	COG2951	lytic endotransglycosylase activity
FY134_RS13030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY134_RS13040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY134_RS13045	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY134_RS13060	COG2816	NAD+ diphosphatase activity
FY134_RS13065	COG1605	Chorismate mutase
FY134_RS13065	COG0077	Prephenate dehydratase
FY134_RS13070	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY134_RS13075	COG3474	cytochrome
FY134_RS13085	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY134_RS13090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY134_RS13100	COG1278	Cold shock
FY134_RS13110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY134_RS13125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY134_RS13125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY134_RS13135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY134_RS13165	COG2900	Belongs to the SlyX family
FY134_RS13175	COG0484	heat shock protein binding
FY134_RS13180	COG0443	Heat shock 70 kDa protein
FY134_RS13195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY134_RS13200	COG1744	ABC transporter substrate-binding protein PnrA-like
FY134_RS13205	COG3845	ABC transporter
FY134_RS13210	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY134_RS13215	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY134_RS13220	COG0295	cytidine deaminase activity
FY134_RS13225	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY134_RS13230	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY134_RS13235	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY134_RS13245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY134_RS13250	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY134_RS13255	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY134_RS13265	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY134_RS13270	COG1845	cytochrome c oxidase, subunit III
FY134_RS13275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY134_RS13285	COG0477	Major facilitator Superfamily
FY134_RS13290	COG0070	glutamate synthase
FY134_RS13290	COG0069	glutamate synthase activity
FY134_RS13290	COG0067	glutamate synthase
FY134_RS13295	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY134_RS13310	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY134_RS13320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY134_RS13350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_RS13370	COG0848	biopolymer transport protein
FY134_RS13380	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY134_RS13395	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY134_RS13400	COG3454	Phosphonate metabolism
FY134_RS13405	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY134_RS13410	COG3639	organic phosphonate transmembrane transporter activity
FY134_RS13415	COG3639	organic phosphonate transmembrane transporter activity
FY134_RS13420	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FY134_RS13425	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY134_RS13435	COG4778	phosphonate C-P lyase system protein PhnL
FY134_RS13440	COG4107	phosphonate C-P lyase system protein PhnK
FY134_RS13445	COG3627	carbon phosphorus lyase activity
FY134_RS13450	COG3626	phosphonate metabolism
FY134_RS13455	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY134_RS13460	COG3624	Phosphonate C-P lyase system protein PhnG
FY134_RS13465	COG2188	Transcriptional regulator
FY134_RS13470	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY134_RS13475	COG0837	glucose binding
FY134_RS13480	COG1803	Methylglyoxal synthase
FY134_RS13485	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY134_RS13490	COG4166	transmembrane transport
FY134_RS13495	COG4174	ABC transporter (Permease)
FY134_RS13500	COG4239	(ABC) transporter, permease
FY134_RS13505	COG4172	Belongs to the ABC transporter superfamily
FY134_RS13510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS13515	COG0174	glutamine synthetase
FY134_RS13520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS13525	COG3265	gluconokinase activity
FY134_RS13530	COG1174	glycine betaine transport
FY134_RS13535	COG1125	glycine betaine transport
FY134_RS13540	COG1174	glycine betaine transport
FY134_RS13545	COG1732	Glycine betaine
FY134_RS13555	COG1959	2 iron, 2 sulfur cluster binding
FY134_RS13560	COG1840	ABC-type Fe3 transport system, periplasmic component
FY134_RS13580	COG0697	spore germination
FY134_RS13595	COG0791	NLP P60 protein
FY134_RS13605	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY134_RS13610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY134_RS13645	COG4964	Belongs to the GSP D family
FY134_RS13695	COG3757	hydrolase, family 25
FY134_RS13700	COG0697	spore germination
FY134_RS13705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY134_RS13735	COG0481	GTPase activity
FY134_RS13740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY134_RS13755	COG1396	sequence-specific DNA binding
FY134_RS13770	COG1917	Cupin 2, conserved barrel domain protein
FY134_RS13770	COG2169	Transcriptional regulator
FY134_RS13775	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY134_RS13800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY134_RS13805	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY134_RS13810	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY134_RS13820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY134_RS13825	COG0072	phenylalanine-tRNA ligase activity
FY134_RS13825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY134_RS13830	COG0667	Aldo Keto reductase
FY134_RS13845	COG0667	Aldo Keto reductase
FY134_RS13850	COG4977	sequence-specific DNA binding
FY134_RS13875	COG1570	exodeoxyribonuclease VII activity
FY134_RS13880	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_RS13890	COG1846	Transcriptional regulator
FY134_RS13895	COG0697	spore germination
FY134_RS13900	COG2309	aminopeptidase activity
FY134_RS13905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY134_RS13910	COG1393	Belongs to the ArsC family
FY134_RS13925	COG1309	transcriptional regulator
FY134_RS13935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY134_RS13935	COG0519	Catalyzes the synthesis of GMP from XMP
FY134_RS13950	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY134_RS13980	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY134_RS13990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY134_RS14000	COG1968	undecaprenyl-diphosphatase activity
FY134_RS14020	COG0284	orotidine-5'-phosphate decarboxylase activity
FY134_RS14030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY134_RS14040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY134_RS14045	COG0792	nuclease activity
FY134_RS14060	COG1175	transmembrane transport
FY134_RS14065	COG0395	ABC-type sugar transport system, permease component
FY134_RS14070	COG3842	ATPase activity
FY134_RS14080	COG0189	ligase activity
FY134_RS14120	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY134_RS14175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY134_RS14190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY134_RS14195	COG1280	lysine exporter protein (LysE YggA)
FY134_RS14200	COG0756	dUTP diphosphatase activity
FY134_RS14205	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY134_RS14210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY134_RS14225	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY134_RS14230	COG2226	methyltransferase
FY134_RS14235	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY134_RS14240	COG1024	Enoyl-CoA hydratase
FY134_RS14245	COG0268	Binds directly to 16S ribosomal RNA
FY134_RS14270	COG0640	Transcriptional regulator
FY134_RS14325	COG3842	ATPase activity
FY134_RS14330	COG4209	transmembrane transport
FY134_RS14335	COG0395	ABC-type sugar transport system, permease component
FY134_RS14340	COG1653	transport
FY134_RS14350	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS14360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_RS14370	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_RS14395	COG1940	carbohydrate kinase activity
FY134_RS14395	COG1846	Transcriptional regulator
FY134_RS14400	COG2197	response regulator
FY134_RS14405	COG0601	transmembrane transport
FY134_RS14410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS14430	COG0747	negative chemotaxis
FY134_RS14445	COG1446	asparaginase
FY134_RS14455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS14460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS14465	COG0601	transmembrane transport
FY134_RS14505	COG1215	transferase activity, transferring glycosyl groups
FY134_RS14515	COG0025	NhaP-type Na H and K H
FY134_RS14520	COG4178	(ABC) transporter
FY134_RS14530	COG1609	Transcriptional regulator
FY134_RS14545	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS14550	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FY134_RS14585	COG1794	racemase activity, acting on amino acids and derivatives
FY134_RS14590	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS14595	COG1309	transcriptional regulator
FY134_RS14600	COG2233	PERMEase
FY134_RS14640	COG1595	DNA-templated transcription, initiation
FY134_RS14650	COG0395	ABC-type sugar transport system, permease component
FY134_RS14655	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY134_RS14665	COG3842	ATPase activity
FY134_RS14700	COG1653	transport
FY134_RS14715	COG3842	ATPase activity
FY134_RS14720	COG0395	ABC-type sugar transport system, permease component
FY134_RS14725	COG1175	transmembrane transport
FY134_RS14755	COG1609	Transcriptional regulator
FY134_RS14765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_RS14770	COG1082	Xylose isomerase domain protein TIM barrel
FY134_RS14775	COG3842	ATPase activity
FY134_RS14780	COG0395	ABC-type sugar transport system, permease component
FY134_RS14785	COG1175	transmembrane transport
FY134_RS14790	COG1653	transport
FY134_RS14795	COG1309	transcriptional regulator
FY134_RS14800	COG0673	inositol 2-dehydrogenase activity
FY134_RS14815	COG0673	inositol 2-dehydrogenase activity
FY134_RS14825	COG1278	Cold shock
FY134_RS14835	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY134_RS14860	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY134_RS14875	COG3842	ATPase activity
FY134_RS14880	COG0395	ABC-type sugar transport system, permease component
FY134_RS14885	COG1175	transmembrane transport
FY134_RS14905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_RS14910	COG3618	amidohydrolase
FY134_RS14915	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_RS14920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_RS14925	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS14930	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY134_RS14935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_RS14940	COG2186	Transcriptional regulator
FY134_RS14990	COG2223	nitrite transmembrane transporter activity
FY134_RS14995	COG0583	DNA-binding transcription factor activity
FY134_RS15000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY134_RS15010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_RS15030	COG1609	Transcriptional regulator
FY134_RS15035	COG1063	alcohol dehydrogenase
FY134_RS15040	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS15050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_RS15055	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY134_RS15060	COG1175	transmembrane transport
FY134_RS15065	COG0395	ABC-type sugar transport system, permease component
FY134_RS15080	COG0395	ABC-type sugar transport system, permease component
FY134_RS15085	COG1175	transmembrane transport
FY134_RS15090	COG2182	Extracellular solute-binding protein
FY134_RS15095	COG0626	cystathionine gamma-synthase activity
FY134_RS15105	COG0328	RNA-DNA hybrid ribonuclease activity
FY134_RS15110	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY134_RS15120	COG1121	(ABC) transporter
FY134_RS15125	COG0523	cobalamin synthesis protein
FY134_RS15140	COG0523	cobalamin synthesis protein
FY134_RS15145	COG1653	transport
FY134_RS15150	COG1175	transmembrane transport
FY134_RS15155	COG0395	ABC-type sugar transport system, permease component
FY134_RS15160	COG3842	ATPase activity
FY134_RS15175	COG3047	cAMP biosynthetic process
FY134_RS15200	COG0583	DNA-binding transcription factor activity
FY134_RS15205	COG1879	ABC-type sugar transport system periplasmic component
FY134_RS15210	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS15215	COG1129	ABC transporter
FY134_RS15225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY134_RS15230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_RS15235	COG3447	MASE1 domain protein
FY134_RS15235	COG5002	protein histidine kinase activity
FY134_RS15235	COG5001	Diguanylate cyclase
FY134_RS15240	COG3257	ureidoglycine aminohydrolase activity
FY134_RS15250	COG5001	Diguanylate cyclase
FY134_RS15255	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY134_RS15265	COG0747	negative chemotaxis
FY134_RS15270	COG0601	transmembrane transport
FY134_RS15275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS15285	COG4608	Belongs to the ABC transporter superfamily
FY134_RS15300	COG0129	dihydroxy-acid dehydratase activity
FY134_RS15305	COG1879	ABC-type sugar transport system periplasmic component
FY134_RS15310	COG1129	ABC transporter
FY134_RS15315	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS15320	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS15325	COG2186	Transcriptional regulator
FY134_RS15335	COG0587	DNA-directed DNA polymerase activity
FY134_RS15365	COG0673	inositol 2-dehydrogenase activity
FY134_RS15375	COG3842	ATPase activity
FY134_RS15380	COG0395	ABC-type sugar transport system, permease component
FY134_RS15385	COG1175	transmembrane transport
FY134_RS15390	COG1653	transport
FY134_RS15400	COG0673	inositol 2-dehydrogenase activity
FY134_RS15415	COG5001	Diguanylate cyclase
FY134_RS15420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS15430	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY134_RS15435	COG2894	cell division
FY134_RS15440	COG0850	regulation of cytokinetic process
FY134_RS15445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY134_RS15450	COG2186	Transcriptional regulator
FY134_RS15455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_RS15465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY134_RS15470	COG1063	alcohol dehydrogenase
FY134_RS15475	COG1312	Catalyzes the dehydration of D-mannonate
FY134_RS15490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_RS15495	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY134_RS15495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY134_RS15500	COG4172	Belongs to the ABC transporter superfamily
FY134_RS15505	COG1921	L-seryl-tRNASec selenium transferase activity
FY134_RS15520	COG3964	amidohydrolase
FY134_RS15530	COG0601	transmembrane transport
FY134_RS15540	COG0438	transferase activity, transferring glycosyl groups
FY134_RS15575	COG4989	oxidoreductase activity
FY134_RS15590	COG3842	ATPase activity
FY134_RS15595	COG1653	transport
FY134_RS15600	COG1175	transmembrane transport
FY134_RS15605	COG0395	ABC-type sugar transport system, permease component
FY134_RS15610	COG1501	Belongs to the glycosyl hydrolase 31 family
FY134_RS15615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_RS15620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_RS15625	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY134_RS15630	COG0352	thiamine-phosphate diphosphorylase activity
FY134_RS15635	COG0351	phosphomethylpyrimidine kinase
FY134_RS15640	COG1522	sequence-specific DNA binding
FY134_RS15645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY134_RS15650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS15665	COG2204	response regulator
FY134_RS15670	COG4191	Histidine kinase
FY134_RS15675	COG1301	dicarboxylic acid transport
FY134_RS15685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY134_RS15690	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS15700	COG1473	amidohydrolase
FY134_RS15720	COG1215	transferase activity, transferring glycosyl groups
FY134_RS15730	COG2942	2-epimerase
FY134_RS15765	COG2197	response regulator
FY134_RS15795	COG3307	-O-antigen
FY134_RS15800	COG1596	polysaccharide export
FY134_RS15805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY134_RS15815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY134_RS15820	COG2972	Histidine kinase
FY134_RS15820	COG0840	transmembrane signaling receptor activity
FY134_RS15825	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_RS15825	COG1388	LysM domain
FY134_RS15835	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS15845	COG2094	Belongs to the DNA glycosylase MPG family
FY134_RS15860	COG1609	Transcriptional regulator
FY134_RS15865	COG1653	transport
FY134_RS15880	COG3842	ATPase activity
FY134_RS15890	COG0673	inositol 2-dehydrogenase activity
FY134_RS15895	COG0602	queuosine metabolic process
FY134_RS15900	COG0720	synthase
FY134_RS15905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY134_RS15910	COG0673	inositol 2-dehydrogenase activity
FY134_RS15925	COG0395	ABC-type sugar transport system, permease component
FY134_RS15930	COG1175	transmembrane transport
FY134_RS15950	COG0583	DNA-binding transcription factor activity
FY134_RS15955	COG0280	phosphate acetyltransferase
FY134_RS15955	COG0281	malic enzyme
FY134_RS15970	COG0765	amino acid transport
FY134_RS15980	COG2079	MmgE PrpD family protein
FY134_RS15985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS15995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS16010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY134_RS16015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY134_RS16020	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY134_RS16025	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY134_RS16030	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS16035	COG1129	ABC transporter
FY134_RS16050	COG1473	amidohydrolase
FY134_RS16070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS16075	COG0601	transmembrane transport
FY134_RS16080	COG0583	DNA-binding transcription factor activity
FY134_RS16085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_RS16090	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY134_RS16110	COG1595	DNA-templated transcription, initiation
FY134_RS16115	COG1120	ATPase activity
FY134_RS16120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_RS16135	COG2226	methyltransferase
FY134_RS16145	COG1120	ATPase activity
FY134_RS16150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_RS16170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY134_RS16180	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS16185	COG0473	3-isopropylmalate dehydrogenase activity
FY134_RS16190	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS16195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS16225	COG0601	transmembrane transport
FY134_RS16230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS16235	COG4172	Belongs to the ABC transporter superfamily
FY134_RS16240	COG1522	sequence-specific DNA binding
FY134_RS16245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS16255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS16260	COG1126	abc transporter atp-binding protein
FY134_RS16275	COG1473	amidohydrolase
FY134_RS16280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS16285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS16290	COG1959	2 iron, 2 sulfur cluster binding
FY134_RS16300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY134_RS16305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS16320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS16325	COG1960	acyl-CoA dehydrogenase activity
FY134_RS16360	COG0667	Aldo Keto reductase
FY134_RS16370	COG0583	DNA-binding transcription factor activity
FY134_RS16375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS16390	COG0747	negative chemotaxis
FY134_RS16395	COG1473	amidohydrolase
FY134_RS16400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS16415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS16420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS16440	COG4608	Belongs to the ABC transporter superfamily
FY134_RS16445	COG0444	Belongs to the ABC transporter superfamily
FY134_RS16455	COG0601	transmembrane transport
FY134_RS16465	COG2186	Transcriptional regulator
FY134_RS16480	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS16490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY134_RS16490	COG3453	Protein conserved in bacteria
FY134_RS16495	COG0640	Transcriptional regulator
FY134_RS16505	COG2391	methyltransferase activity
FY134_RS16510	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY134_RS16520	COG0022	dehydrogenase e1 component
FY134_RS16530	COG1960	acyl-CoA dehydrogenase activity
FY134_RS16535	COG0183	Belongs to the thiolase family
FY134_RS16545	COG1960	acyl-CoA dehydrogenase activity
FY134_RS16550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY134_RS16565	COG1024	Enoyl-CoA hydratase
FY134_RS16570	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY134_RS16575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY134_RS16580	COG4952	isomerase
FY134_RS16585	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS16585	COG3347	Dehydrogenase
FY134_RS16590	COG1349	DNA-binding transcription factor activity
FY134_RS16600	COG1129	ABC transporter
FY134_RS16605	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS16615	COG3254	rhamnose metabolic process
FY134_RS16630	COG2264	protein methyltransferase activity
FY134_RS16635	COG5001	Diguanylate cyclase
FY134_RS16650	COG4335	DNA alkylation repair
FY134_RS16655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY134_RS16660	COG4208	sulfate ABC transporter
FY134_RS16670	COG4150	thiosulfate binding
FY134_RS16675	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY134_RS16690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY134_RS16700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY134_RS16710	COG1040	competence protein
FY134_RS16715	COG2226	methyltransferase
FY134_RS16730	COG0494	nUDIX hydrolase
FY134_RS16740	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY134_RS16745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY134_RS16750	COG0653	protein targeting
FY134_RS16795	COG1312	Catalyzes the dehydration of D-mannonate
FY134_RS16800	COG0246	Mannitol dehydrogenase
FY134_RS16820	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS16830	COG1129	ABC transporter
FY134_RS16860	COG2376	Dihydroxyacetone kinase
FY134_RS16865	COG0471	metal ion transport
FY134_RS16865	COG3273	potassium ion transport
FY134_RS16885	COG0438	transferase activity, transferring glycosyl groups
FY134_RS16895	COG2244	polysaccharide biosynthetic process
FY134_RS16915	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY134_RS16925	COG3206	protein involved in exopolysaccharide biosynthesis
FY134_RS16925	COG0489	protein tyrosine kinase activity
FY134_RS16945	COG0438	transferase activity, transferring glycosyl groups
FY134_RS16950	COG0438	transferase activity, transferring glycosyl groups
FY134_RS16965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY134_RS16970	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY134_RS16970	COG2273	Hydrolase Family 16
FY134_RS17015	COG1396	sequence-specific DNA binding
FY134_RS17025	COG1129	ABC transporter
FY134_RS17030	COG4214	carbohydrate transport
FY134_RS17035	COG4213	ABC transporter substrate-binding protein
FY134_RS17050	COG0346	lactoylglutathione lyase activity
FY134_RS17055	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY134_RS17055	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY134_RS17060	COG4770	biotin carboxylase activity
FY134_RS17070	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY134_RS17080	COG0625	glutathione transferase activity
FY134_RS17085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY134_RS17090	COG1396	sequence-specific DNA binding
FY134_RS17090	COG3800	Transcriptional regulator
FY134_RS17100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY134_RS17110	COG0300	oxidoreductase activity
FY134_RS17120	COG2096	Adenosyltransferase
FY134_RS17130	COG2086	electron transfer activity
FY134_RS17140	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY134_RS17145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY134_RS17150	COG0165	Argininosuccinate lyase
FY134_RS17185	COG2884	Cell division ATP-binding protein ftsE
FY134_RS17205	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY134_RS17215	COG0287	Prephenate dehydrogenase
FY134_RS17220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY134_RS17225	COG2226	methyltransferase
FY134_RS17230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY134_RS17250	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY134_RS17255	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY134_RS17285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY134_RS17290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY134_RS17300	COG4974	Belongs to the 'phage' integrase family
FY134_RS17305	COG0825	malonyl-CoA metabolic process
FY134_RS17310	COG3034	peptidoglycan biosynthetic process
FY134_RS17315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY134_RS17315	COG0425	Belongs to the sulfur carrier protein TusA family
FY134_RS17320	COG0523	cobalamin synthesis protein
FY134_RS17325	COG1686	Belongs to the peptidase S11 family
FY134_RS17330	COG1473	amidohydrolase
FY134_RS17335	COG1959	2 iron, 2 sulfur cluster binding
FY134_RS17340	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FY134_RS17380	COG2226	methyltransferase
FY134_RS17415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY134_RS17435	COG1629	transport
FY134_RS17435	COG4774	siderophore transport
FY134_RS17440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FY134_RS17445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_RS17450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_RS17455	COG1120	ATPase activity
FY134_RS17470	COG4953	penicillin-binding protein 1C
FY134_RS17475	COG2373	Large extracellular alpha-helical protein
FY134_RS17480	COG2835	tetraacyldisaccharide 4'-kinase activity
FY134_RS17490	COG3118	belongs to the thioredoxin family
FY134_RS17505	COG0625	glutathione transferase activity
FY134_RS17515	COG0482	sulfurtransferase activity
FY134_RS17530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY134_RS17545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY134_RS17550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY134_RS17555	COG0037	tRNA processing
FY134_RS17565	COG2885	chlorophyll binding
FY134_RS17570	COG0823	Involved in the tonB-independent uptake of proteins
FY134_RS17590	COG0824	Thioesterase
FY134_RS17600	COG0494	nUDIX hydrolase
FY134_RS17605	COG2318	DinB family
FY134_RS17615	COG2255	four-way junction helicase activity
FY134_RS17620	COG0632	four-way junction helicase activity
FY134_RS17625	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY134_RS17630	COG0840	transmembrane signaling receptor activity
FY134_RS17635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS17640	COG0217	transcriptional regulatory protein
FY134_RS17655	COG1692	metallophosphoesterase
FY134_RS17665	COG1253	flavin adenine dinucleotide binding
FY134_RS17700	COG0126	phosphoglycerate kinase activity
FY134_RS17705	COG3588	fructose-bisphosphate aldolase
FY134_RS17730	COG0254	rRNA binding
FY134_RS17735	COG1132	(ABC) transporter
FY134_RS17755	COG0483	inositol monophosphate 1-phosphatase activity
FY134_RS17785	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY134_RS17790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY134_RS17795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY134_RS17800	COG0457	Tetratricopeptide repeat
FY134_RS17805	COG3750	Belongs to the UPF0335 family
FY134_RS17825	COG0469	pyruvate kinase activity
FY134_RS17830	COG3108	Peptidase M15
FY134_RS17835	COG2204	response regulator
FY134_RS17840	COG1164	Oligoendopeptidase f
FY134_RS17845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY134_RS17855	COG5310	Homospermidine synthase
FY134_RS17865	COG0737	Belongs to the 5'-nucleotidase family
FY134_RS17870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY134_RS17875	COG0330	HflC and HflK could
FY134_RS17905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY134_RS17910	COG2951	lytic endotransglycosylase activity
FY134_RS17925	COG2205	protein histidine kinase activity
FY134_RS17940	COG0070	glutamate synthase
FY134_RS17940	COG0069	glutamate synthase activity
FY134_RS17940	COG0067	glutamate synthase
FY134_RS17950	COG0745	RESPONSE REGULATOR receiver
FY134_RS17955	COG2205	protein histidine kinase activity
FY134_RS17960	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY134_RS17965	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY134_RS17975	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY134_RS17990	COG0252	asparaginase activity
FY134_RS18000	COG1027	Aspartate ammonia-lyase
FY134_RS18005	COG2186	Transcriptional regulator
FY134_RS18040	COG4176	ABC-type proline glycine betaine transport system permease component
FY134_RS18045	COG0517	IMP dehydrogenase activity
FY134_RS18045	COG4175	Glycine betaine
FY134_RS18050	COG2986	histidine ammonia-lyase
FY134_RS18055	COG2814	Major facilitator Superfamily
FY134_RS18070	COG1522	sequence-specific DNA binding
FY134_RS18075	COG0583	DNA-binding transcription factor activity
FY134_RS18080	COG0667	Aldo Keto reductase
FY134_RS18090	COG1335	isochorismatase
FY134_RS18100	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS18105	COG3254	rhamnose metabolic process
FY134_RS18120	COG2721	sulfolactate sulfo-lyase activity
FY134_RS18125	COG1129	ABC transporter
FY134_RS18135	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS18140	COG1879	ABC-type sugar transport system periplasmic component
FY134_RS18175	COG0583	DNA-binding transcription factor activity
FY134_RS18215	COG2307	Protein conserved in bacteria
FY134_RS18215	COG2308	Evidence 4 Homologs of previously reported genes of
FY134_RS18230	COG0488	(ABC) transporter
FY134_RS18235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_RS18240	COG1304	FMN binding
FY134_RS18250	COG1846	Transcriptional regulator
FY134_RS18260	COG1070	Carbohydrate kinase
FY134_RS18265	COG1830	Aldolase
FY134_RS18270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY134_RS18275	COG0667	Aldo Keto reductase
FY134_RS18285	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS18290	COG1129	ABC transporter
FY134_RS18295	COG1879	ABC-type sugar transport system periplasmic component
FY134_RS18430	COG0071	Belongs to the small heat shock protein (HSP20) family
FY134_RS18445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY134_RS18460	COG0395	ABC-type sugar transport system, permease component
FY134_RS18475	COG3842	ATPase activity
FY134_RS18490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY134_RS18490	COG1648	precorrin-2 dehydrogenase activity
FY134_RS18495	COG0243	molybdopterin cofactor binding
FY134_RS18505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY134_RS18510	COG1116	anion transmembrane transporter activity
FY134_RS18515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_RS18520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_RS18530	COG3707	response regulator
FY134_RS18535	COG1802	Transcriptional regulator
FY134_RS18540	COG1914	H( )-stimulated, divalent metal cation uptake system
FY134_RS18545	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY134_RS18550	COG4336	lyase activity
FY134_RS18555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY134_RS18560	COG4770	biotin carboxylase activity
FY134_RS18565	COG0366	Alpha amylase catalytic
FY134_RS18575	COG4771	TonB-dependent receptor
FY134_RS18600	COG1414	Transcriptional regulator
FY134_RS18605	COG1475	DNA binding
FY134_RS18610	COG1192	Involved in chromosome partitioning
FY134_RS18640	COG0596	Alpha beta hydrolase
FY134_RS18645	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY134_RS18655	COG2986	histidine ammonia-lyase
FY134_RS18660	COG1228	amidohydrolase
FY134_RS18665	COG0402	S-adenosylhomocysteine deaminase activity
FY134_RS18710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS18720	COG2423	ornithine cyclodeaminase activity
FY134_RS18735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS18740	COG3938	Belongs to the proline racemase family
FY134_RS18745	COG4176	ABC-type proline glycine betaine transport system permease component
FY134_RS18755	COG4175	Glycine betaine
FY134_RS18755	COG3448	diguanylate cyclase activity
FY134_RS18765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS18770	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS18775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_RS18805	COG0673	inositol 2-dehydrogenase activity
FY134_RS18810	COG0673	inositol 2-dehydrogenase activity
FY134_RS18820	COG1175	transmembrane transport
FY134_RS18825	COG0395	ABC-type sugar transport system, permease component
FY134_RS18830	COG3842	ATPase activity
FY134_RS18840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_RS18845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY134_RS18870	COG0583	DNA-binding transcription factor activity
FY134_RS18875	COG0346	lactoylglutathione lyase activity
FY134_RS18890	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY134_RS18905	COG2814	Major facilitator Superfamily
FY134_RS18920	COG0583	DNA-binding transcription factor activity
FY134_RS18925	COG0477	Major facilitator Superfamily
FY134_RS18975	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY134_RS18985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY134_RS18990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY134_RS18995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY134_RS19025	COG0010	Belongs to the arginase family
FY134_RS19035	COG0697	spore germination
FY134_RS19040	COG0673	inositol 2-dehydrogenase activity
FY134_RS19060	COG0477	Major facilitator Superfamily
FY134_RS19065	COG0642	Histidine kinase
FY134_RS19075	COG2194	sulfuric ester hydrolase activity
FY134_RS19085	COG0583	DNA-binding transcription factor activity
FY134_RS19090	COG4774	siderophore transport
FY134_RS19105	COG1120	ATPase activity
FY134_RS19115	COG3474	cytochrome
FY134_RS19120	COG2137	regulation of response to DNA damage stimulus
FY134_RS19125	COG3386	PFAM SMP-30 Gluconolaconase
FY134_RS19135	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS19140	COG1129	ABC transporter
FY134_RS19145	COG1879	ABC-type sugar transport system periplasmic component
FY134_RS19150	COG4585	Histidine kinase
FY134_RS19155	COG2197	response regulator
FY134_RS19165	COG2133	pyrroloquinoline quinone binding
FY134_RS19175	COG0500	methyltransferase
FY134_RS19180	COG0564	pseudouridine synthase activity
FY134_RS19195	COG0517	IMP dehydrogenase activity
FY134_RS19195	COG4175	Glycine betaine
FY134_RS19200	COG4176	ABC-type proline glycine betaine transport system permease component
FY134_RS19210	COG0784	Response regulator, receiver
FY134_RS19210	COG4191	Histidine kinase
FY134_RS19215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY134_RS19220	COG3206	protein involved in exopolysaccharide biosynthesis
FY134_RS19220	COG0489	protein tyrosine kinase activity
FY134_RS19225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY134_RS19230	COG1215	transferase activity, transferring glycosyl groups
FY134_RS19235	COG1215	transferase activity, transferring glycosyl groups
FY134_RS19240	COG1215	transferase activity, transferring glycosyl groups
FY134_RS19245	COG0438	transferase activity, transferring glycosyl groups
FY134_RS19250	COG2273	Hydrolase Family 16
FY134_RS19255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY134_RS19260	COG2244	polysaccharide biosynthetic process
FY134_RS19265	COG0463	Glycosyl transferase, family 2
FY134_RS19270	COG2327	Polysaccharide pyruvyl transferase
FY134_RS19275	COG1215	transferase activity, transferring glycosyl groups
FY134_RS19295	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY134_RS19300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS19315	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_RS19315	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY134_RS19340	COG0033	Phosphoglucomutase
FY134_RS19345	COG0297	glycogen (starch) synthase activity
FY134_RS19350	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY134_RS19355	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY134_RS19360	COG0058	SHG alpha-glucan phosphorylase activity
FY134_RS19370	COG1794	racemase activity, acting on amino acids and derivatives
FY134_RS19375	COG1522	sequence-specific DNA binding
FY134_RS19385	COG2084	Dehydrogenase
FY134_RS19390	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS19395	COG1063	alcohol dehydrogenase
FY134_RS19405	COG4988	ABC transporter
FY134_RS19410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY134_RS19420	COG1294	oxidase, subunit
FY134_RS19450	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY134_RS19455	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY134_RS19485	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY134_RS19490	COG0539	negative regulation of cytoplasmic translation
FY134_RS19520	COG4221	oxidoreductase activity
FY134_RS19525	COG0006	proline dipeptidase activity
FY134_RS19530	COG0747	negative chemotaxis
FY134_RS19535	COG0601	transmembrane transport
FY134_RS19540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS19545	COG0444	Belongs to the ABC transporter superfamily
FY134_RS19550	COG4608	Belongs to the ABC transporter superfamily
FY134_RS19565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS19590	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY134_RS19610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY134_RS19615	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS19635	COG4993	Dehydrogenase
FY134_RS19640	COG3685	Protein conserved in bacteria
FY134_RS19670	COG0693	protein deglycase activity
FY134_RS19690	COG0189	ligase activity
FY134_RS19695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_RS19700	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY134_RS19710	COG0583	DNA-binding transcription factor activity
FY134_RS19715	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS19720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_RS19725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_RS19730	COG1116	anion transmembrane transporter activity
FY134_RS19740	COG1522	sequence-specific DNA binding
FY134_RS19755	COG0784	Response regulator, receiver
FY134_RS19765	COG3920	Histidine kinase
FY134_RS19775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY134_RS19790	COG0019	diaminopimelate decarboxylase activity
FY134_RS19800	COG0513	Belongs to the DEAD box helicase family
FY134_RS19805	COG0527	aspartate kinase activity
FY134_RS19815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY134_RS19820	COG2890	protein-(glutamine-N5) methyltransferase activity
FY134_RS19830	COG0542	response to heat
FY134_RS19835	COG0739	heme binding
FY134_RS19835	COG0741	lytic transglycosylase activity
FY134_RS19835	COG1196	nuclear chromosome segregation
FY134_RS19870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_RS19880	COG2186	Transcriptional regulator
FY134_RS19885	COG0747	negative chemotaxis
FY134_RS19890	COG0601	transmembrane transport
FY134_RS19895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS19900	COG4172	Belongs to the ABC transporter superfamily
FY134_RS19905	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_RS19940	COG1881	PFAM PEBP family protein
FY134_RS19970	COG1278	Cold shock
FY134_RS19985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY134_RS20005	COG0300	oxidoreductase activity
FY134_RS20015	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY134_RS20015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_RS20020	COG4311	Sarcosine oxidase, delta subunit
FY134_RS20025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS20030	COG4977	sequence-specific DNA binding
FY134_RS20040	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY134_RS20045	COG2218	PFAM glutamate synthase alpha subunit domain protein
FY134_RS20050	COG0069	glutamate synthase activity
FY134_RS20055	COG0174	glutamine synthetase
FY134_RS20075	COG0765	amino acid transport
FY134_RS20080	COG1126	abc transporter atp-binding protein
FY134_RS20085	COG1454	alcohol dehydrogenase
FY134_RS20095	COG2267	carboxylic ester hydrolase activity
FY134_RS20105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS20110	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS20130	COG1177	transmembrane transport
FY134_RS20145	COG3842	ATPase activity
FY134_RS20150	COG0395	ABC-type sugar transport system, permease component
FY134_RS20155	COG1175	transmembrane transport
FY134_RS20165	COG3976	FMN-binding domain protein
FY134_RS20165	COG1053	succinate dehydrogenase
FY134_RS20170	COG1609	Transcriptional regulator
FY134_RS20180	COG4172	Belongs to the ABC transporter superfamily
FY134_RS20185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS20190	COG0601	transmembrane transport
FY134_RS20200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_RS20215	COG2828	Protein conserved in bacteria
FY134_RS20220	COG0583	DNA-binding transcription factor activity
FY134_RS20230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY134_RS20240	COG1280	lysine exporter protein (LysE YggA)
FY134_RS20250	COG0494	nUDIX hydrolase
FY134_RS20255	COG0583	DNA-binding transcription factor activity
FY134_RS20265	COG0511	ligase activity, forming carbon-carbon bonds
FY134_RS20270	COG0439	Biotin carboxylase
FY134_RS20285	COG1984	allophanate hydrolase subunit 2
FY134_RS20290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY134_RS20295	COG0436	Aminotransferase
FY134_RS20305	COG4221	oxidoreductase activity
FY134_RS20310	COG0765	amino acid transport
FY134_RS20315	COG0765	amino acid transport
FY134_RS20320	COG1126	abc transporter atp-binding protein
FY134_RS20325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS20330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY134_RS20345	COG0583	DNA-binding transcription factor activity
FY134_RS20355	COG0583	DNA-binding transcription factor activity
FY134_RS20360	COG2814	Major facilitator Superfamily
FY134_RS20375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY134_RS20385	COG2207	Transcriptional regulator
FY134_RS20390	COG0668	transmembrane transport
FY134_RS20400	COG4566	intracellular signal transduction
FY134_RS20420	COG0668	transmembrane transport
FY134_RS20425	COG4191	Histidine kinase
FY134_RS20430	COG0784	Response regulator, receiver
FY134_RS20430	COG2205	protein histidine kinase activity
FY134_RS20430	COG5002	protein histidine kinase activity
FY134_RS20435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY134_RS20450	COG0047	phosphoribosylformylglycinamidine synthase activity
FY134_RS20465	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_RS20465	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY134_RS20475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY134_RS20490	COG1309	transcriptional regulator
FY134_RS20495	COG1063	alcohol dehydrogenase
FY134_RS20505	COG1879	ABC-type sugar transport system periplasmic component
FY134_RS20515	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS20665	COG5001	Diguanylate cyclase
FY134_RS20675	COG1253	flavin adenine dinucleotide binding
FY134_RS20690	COG3842	ATPase activity
FY134_RS20695	COG0395	ABC-type sugar transport system, permease component
FY134_RS20700	COG1175	transmembrane transport
FY134_RS20705	COG1653	transport
FY134_RS20715	COG0673	inositol 2-dehydrogenase activity
FY134_RS20720	COG1609	Transcriptional regulator
FY134_RS20735	COG0583	DNA-binding transcription factor activity
FY134_RS20745	COG1879	ABC-type sugar transport system periplasmic component
FY134_RS20750	COG1129	ABC transporter
FY134_RS20755	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS20760	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS20765	COG1609	Transcriptional regulator
FY134_RS20775	COG0673	inositol 2-dehydrogenase activity
FY134_RS20800	COG3189	MarR family transcriptional regulator
FY134_RS20815	COG1960	acyl-CoA dehydrogenase activity
FY134_RS20820	COG0583	DNA-binding transcription factor activity
FY134_RS20825	COG1609	Transcriptional regulator
FY134_RS20835	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY134_RS20845	COG3842	ATPase activity
FY134_RS20855	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY134_RS20865	COG1473	amidohydrolase
FY134_RS20880	COG0747	negative chemotaxis
FY134_RS20885	COG0601	transmembrane transport
FY134_RS20890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS20895	COG0444	Belongs to the ABC transporter superfamily
FY134_RS20900	COG4608	Belongs to the ABC transporter superfamily
FY134_RS20905	COG0583	DNA-binding transcription factor activity
FY134_RS20910	COG0747	negative chemotaxis
FY134_RS20920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS20925	COG0154	amidase activity
FY134_RS20930	COG0693	protein deglycase activity
FY134_RS20940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS20945	COG0601	transmembrane transport
FY134_RS20955	COG1473	amidohydrolase
FY134_RS20960	COG4172	Belongs to the ABC transporter superfamily
FY134_RS20965	COG2390	Transcriptional regulator
FY134_RS20975	COG1175	transmembrane transport
FY134_RS20980	COG0395	ABC-type sugar transport system, permease component
FY134_RS20995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY134_RS21000	COG1069	ribulokinase activity
FY134_RS21005	COG1737	Transcriptional regulator
FY134_RS21025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY134_RS21035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY134_RS21040	COG1414	Transcriptional regulator
FY134_RS21045	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS21055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY134_RS21060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY134_RS21065	COG1121	(ABC) transporter
FY134_RS21070	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY134_RS21080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY134_RS21085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY134_RS21090	COG3273	potassium ion transport
FY134_RS21090	COG0471	metal ion transport
FY134_RS21095	COG1253	flavin adenine dinucleotide binding
FY134_RS21100	COG1309	transcriptional regulator
FY134_RS21115	COG1609	Transcriptional regulator
FY134_RS21120	COG1070	Carbohydrate kinase
FY134_RS21125	COG2115	Belongs to the xylose isomerase family
FY134_RS21135	COG0778	Nitroreductase
FY134_RS21140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY134_RS21145	COG2011	ABC-type metal ion transport system permease component
FY134_RS21155	COG3300	MHYT domain
FY134_RS21155	COG5001	Diguanylate cyclase
FY134_RS21160	COG1054	Belongs to the UPF0176 family
FY134_RS21170	COG2954	triphosphatase activity
FY134_RS21175	COG0800	Aldolase
FY134_RS21200	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY134_RS21225	COG2814	Major facilitator Superfamily
FY134_RS21235	COG0523	cobalamin synthesis protein
FY134_RS21245	COG1846	Transcriptional regulator
FY134_RS21250	COG1609	Transcriptional regulator
FY134_RS21260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_RS21265	COG0673	inositol 2-dehydrogenase activity
FY134_RS21270	COG3718	enzyme involved in inositol metabolism
FY134_RS21280	COG3962	Belongs to the TPP enzyme family
FY134_RS21285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_RS21315	COG0683	leucine binding
FY134_RS21330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS21340	COG0747	negative chemotaxis
FY134_RS21345	COG4172	Belongs to the ABC transporter superfamily
FY134_RS21355	COG1082	Xylose isomerase domain protein TIM barrel
FY134_RS21355	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FY134_RS21365	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY134_RS21370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY134_RS21375	COG1126	abc transporter atp-binding protein
FY134_RS21380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS21385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS21390	COG0765	amino acid transport
FY134_RS21395	COG0765	amino acid transport
FY134_RS21405	COG3485	protocatechuate 3,4-dioxygenase
FY134_RS21410	COG3485	protocatechuate 3,4-dioxygenase
FY134_RS21415	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY134_RS21425	COG0583	DNA-binding transcription factor activity
FY134_RS21440	COG1414	Transcriptional regulator
FY134_RS21450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY134_RS21455	COG0183	Belongs to the thiolase family
FY134_RS21460	COG1609	Transcriptional regulator
FY134_RS21475	COG1082	Xylose isomerase domain protein TIM barrel
FY134_RS21480	COG0673	inositol 2-dehydrogenase activity
FY134_RS21490	COG1609	Transcriptional regulator
FY134_RS21495	COG0395	ABC-type sugar transport system, permease component
FY134_RS21500	COG1175	transmembrane transport
FY134_RS21505	COG3842	ATPase activity
FY134_RS21515	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY134_RS21550	COG3842	ATPase activity
FY134_RS21555	COG4149	molybdate abc transporter
FY134_RS21565	COG0584	glycerophosphoryl diester phosphodiesterase
FY134_RS21570	COG0483	inositol monophosphate 1-phosphatase activity
FY134_RS21575	COG0300	oxidoreductase activity
FY134_RS21585	COG1940	carbohydrate kinase activity
FY134_RS21585	COG1846	Transcriptional regulator
FY134_RS21595	COG3842	ATPase activity
FY134_RS21615	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY134_RS21650	COG0385	Bile acid
FY134_RS21655	COG0667	Aldo Keto reductase
FY134_RS21660	COG0583	DNA-binding transcription factor activity
FY134_RS21670	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY134_RS21680	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS21690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_RS21705	COG1132	(ABC) transporter
FY134_RS21730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY134_RS21745	COG0463	Glycosyl transferase, family 2
FY134_RS21765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FY134_RS21775	COG4106	trans-aconitate 2-methyltransferase activity
FY134_RS21780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY134_RS21785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY134_RS21795	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY134_RS21800	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY134_RS21805	COG1088	dTDP-glucose 4,6-dehydratase activity
FY134_RS21810	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY134_RS21825	COG0444	Belongs to the ABC transporter superfamily
FY134_RS21830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS21835	COG0601	transmembrane transport
FY134_RS21840	COG2186	Transcriptional regulator
FY134_RS21845	COG1312	Catalyzes the dehydration of D-mannonate
FY134_RS21850	COG0747	negative chemotaxis
FY134_RS21860	COG5001	Diguanylate cyclase
FY134_RS21860	COG3300	MHYT domain
FY134_RS21865	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS21875	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY134_RS21885	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY134_RS21890	COG0306	phosphate transporter
FY134_RS21895	COG1392	Phosphate transport regulator
FY134_RS21915	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY134_RS21930	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS21945	COG3119	arylsulfatase activity
FY134_RS21950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_RS21955	COG3842	ATPase activity
FY134_RS21960	COG0165	Argininosuccinate lyase
FY134_RS21965	COG0395	ABC-type sugar transport system, permease component
FY134_RS21970	COG1175	transmembrane transport
FY134_RS21975	COG2182	Extracellular solute-binding protein
FY134_RS21980	COG1940	carbohydrate kinase activity
FY134_RS22005	COG1486	melibiose metabolic process
FY134_RS22010	COG0747	negative chemotaxis
FY134_RS22015	COG0601	transmembrane transport
FY134_RS22020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS22025	COG4172	Belongs to the ABC transporter superfamily
FY134_RS22030	COG1486	melibiose metabolic process
FY134_RS22035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_RS22040	COG1129	ABC transporter
FY134_RS22040	COG0842	Transport permease protein
FY134_RS22045	COG0842	Transport permease protein
FY134_RS22060	COG0784	Response regulator, receiver
FY134_RS22065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY134_RS22075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_RS22080	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY134_RS22095	COG0765	amino acid transport
FY134_RS22105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS22115	COG3938	Belongs to the proline racemase family
FY134_RS22130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS22135	COG0765	amino acid transport
FY134_RS22140	COG0765	amino acid transport
FY134_RS22150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_RS22165	COG0402	S-adenosylhomocysteine deaminase activity
FY134_RS22175	COG0601	transmembrane transport
FY134_RS22180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS22190	COG0402	S-adenosylhomocysteine deaminase activity
FY134_RS22195	COG0444	Belongs to the ABC transporter superfamily
FY134_RS22200	COG4608	Belongs to the ABC transporter superfamily
FY134_RS22205	COG1802	Transcriptional regulator
FY134_RS22210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY134_RS22235	COG3383	formate dehydrogenase (NAD+) activity
FY134_RS22245	COG2223	nitrite transmembrane transporter activity
FY134_RS22275	COG3237	CsbD-like
FY134_RS22280	COG2197	response regulator
FY134_RS22285	COG2186	Transcriptional regulator
FY134_RS22290	COG0747	negative chemotaxis
FY134_RS22295	COG0601	transmembrane transport
FY134_RS22300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS22305	COG0405	Gamma-glutamyltransferase
FY134_RS22315	COG0483	inositol monophosphate 1-phosphatase activity
FY134_RS22325	COG3842	ATPase activity
FY134_RS22350	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY134_RS22355	COG3181	Tripartite tricarboxylate transporter family receptor
FY134_RS22360	COG5265	(ABC) transporter
FY134_RS22365	COG0488	(ABC) transporter
FY134_RS22390	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY134_RS22395	COG0840	transmembrane signaling receptor activity
FY134_RS22405	COG0110	maltose O-acetyltransferase activity
FY134_RS22415	COG1063	alcohol dehydrogenase
FY134_RS22420	COG3284	Transcriptional regulator
FY134_RS22440	COG1129	ABC transporter
FY134_RS22445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS22450	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS22465	COG1082	Xylose isomerase domain protein TIM barrel
FY134_RS22475	COG1126	abc transporter atp-binding protein
FY134_RS22480	COG0765	amino acid transport
FY134_RS22485	COG0765	amino acid transport
FY134_RS22490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS22495	COG3608	succinylglutamate desuccinylase aspartoacylase
FY134_RS22500	COG0006	proline dipeptidase activity
FY134_RS22505	COG2423	ornithine cyclodeaminase activity
FY134_RS22510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY134_RS22515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY134_RS22520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY134_RS22525	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS22530	COG1522	sequence-specific DNA binding
FY134_RS22535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY134_RS22565	COG2140	Oxalate decarboxylase
FY134_RS22580	COG4566	intracellular signal transduction
FY134_RS22590	COG0243	molybdopterin cofactor binding
FY134_RS22595	COG0783	Belongs to the Dps family
FY134_RS22615	COG0596	Alpha beta hydrolase
FY134_RS22625	COG1764	response to oxidative stress
FY134_RS22640	COG0596	Alpha beta hydrolase
FY134_RS22675	COG4191	Histidine kinase
FY134_RS22675	COG0784	Response regulator, receiver
FY134_RS22685	COG1840	ABC-type Fe3 transport system, periplasmic component
FY134_RS22690	COG1840	ABC-type Fe3 transport system, periplasmic component
FY134_RS22700	COG3842	ATPase activity
FY134_RS22705	COG0483	inositol monophosphate 1-phosphatase activity
FY134_RS22720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_RS22750	COG2197	response regulator
FY134_RS22755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY134_RS22760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY134_RS22770	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY134_RS22775	COG4310	Domain of unknown function (DUF2172)
FY134_RS22780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_RS22785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FY134_RS22790	COG2197	response regulator
FY134_RS22795	COG4566	intracellular signal transduction
FY134_RS22825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY134_RS22845	COG0438	transferase activity, transferring glycosyl groups
FY134_RS22860	COG1522	sequence-specific DNA binding
FY134_RS22880	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS22895	COG1414	Transcriptional regulator
FY134_RS22905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_RS22930	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FY134_RS22960	COG1349	DNA-binding transcription factor activity
FY134_RS22965	COG1879	ABC-type sugar transport system periplasmic component
FY134_RS22970	COG1129	ABC transporter
FY134_RS22975	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS22980	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS23000	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS23005	COG1280	lysine exporter protein (LysE YggA)
FY134_RS23020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY134_RS23080	COG4529	Protein conserved in bacteria
FY134_RS23130	COG3422	double-strand break repair
FY134_RS23145	COG1192	Involved in chromosome partitioning
FY134_RS23150	COG1475	DNA binding
FY134_RS23155	COG0640	Transcriptional regulator
FY134_RS23170	COG1126	abc transporter atp-binding protein
FY134_RS23180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS23185	COG1609	Transcriptional regulator
FY134_RS23205	COG1733	regulation of RNA biosynthetic process
FY134_RS23325	COG4691	Plasmid stability protein
FY134_RS23330	COG1487	ribonuclease activity
FY134_RS23345	COG0534	Mate efflux family protein
FY134_RS23350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY134_RS23365	COG0596	Alpha beta hydrolase
FY134_RS23410	COG3920	Histidine kinase
FY134_RS23425	COG0784	Response regulator, receiver
FY134_RS23450	COG4095	Psort location CytoplasmicMembrane, score
FY134_RS23485	COG0753	catalase activity
FY134_RS23490	COG3685	Protein conserved in bacteria
FY134_RS23525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY134_RS23530	COG0297	glycogen (starch) synthase activity
FY134_RS23610	COG1609	Transcriptional regulator
FY134_RS23635	COG0673	inositol 2-dehydrogenase activity
FY134_RS23640	COG4608	Belongs to the ABC transporter superfamily
FY134_RS23650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS23655	COG0601	transmembrane transport
FY134_RS23660	COG0747	negative chemotaxis
FY134_RS23665	COG1802	Transcriptional regulator
FY134_RS23675	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_RS23780	COG1175	transmembrane transport
FY134_RS23785	COG0395	ABC-type sugar transport system, permease component
FY134_RS23795	COG3842	ATPase activity
FY134_RS23800	COG1737	Transcriptional regulator
FY134_RS23805	COG1846	Transcriptional regulator
FY134_RS23820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_RS23830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS23835	COG0601	transmembrane transport
FY134_RS23840	COG0747	negative chemotaxis
FY134_RS23850	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY134_RS23855	COG1454	alcohol dehydrogenase
FY134_RS23865	COG3395	kinase activity
FY134_RS23880	COG2020	methyltransferase activity
FY134_RS23890	COG3118	belongs to the thioredoxin family
FY134_RS23890	COG0492	ferredoxin-NADP+ reductase activity
FY134_RS23895	COG1309	transcriptional regulator
FY134_RS23920	COG3177	Filamentation induced by cAMP protein fic
FY134_RS23925	COG1309	transcriptional regulator
FY134_RS23950	COG0372	Belongs to the citrate synthase family
FY134_RS24000	COG4423	Transcription factor
FY134_RS24015	COG0840	transmembrane signaling receptor activity
FY134_RS24030	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY134_RS24035	COG1070	Carbohydrate kinase
FY134_RS24045	COG1175	transmembrane transport
FY134_RS24055	COG3842	ATPase activity
FY134_RS24065	COG2390	Transcriptional regulator
FY134_RS24130	COG0714	Associated with various cellular activities
FY134_RS24135	COG3256	nitric oxide reductase
FY134_RS24150	COG1845	cytochrome c oxidase, subunit III
FY134_RS24165	COG0163	prenyltransferase activity
FY134_RS24170	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY134_RS24175	COG3189	MarR family transcriptional regulator
FY134_RS24185	COG0826	peptidase U32
FY134_RS24210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY134_RS24220	COG4459	periplasmic nitrate reductase
FY134_RS24235	COG0243	molybdopterin cofactor binding
FY134_RS24245	COG3005	denitrification pathway
FY134_RS24285	COG2268	Band 7 protein
FY134_RS24305	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS24310	COG0583	DNA-binding transcription factor activity
FY134_RS24335	COG0583	DNA-binding transcription factor activity
FY134_RS24350	COG1177	transmembrane transport
FY134_RS24355	COG3842	ATPase activity
FY134_RS24360	COG2072	flavoprotein involved in K transport
FY134_RS24380	COG0534	Mate efflux family protein
FY134_RS24405	COG1609	Transcriptional regulator
FY134_RS24410	COG1082	Xylose isomerase domain protein TIM barrel
FY134_RS24415	COG0673	inositol 2-dehydrogenase activity
FY134_RS24425	COG1082	Xylose isomerase domain protein TIM barrel
FY134_RS24435	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS24455	COG0840	transmembrane signaling receptor activity
FY134_RS24455	COG2972	Histidine kinase
FY134_RS24470	COG4221	oxidoreductase activity
FY134_RS24475	COG1902	pentaerythritol trinitrate reductase activity
FY134_RS24480	COG0596	Alpha beta hydrolase
FY134_RS24490	COG3831	ATPase activity
FY134_RS24495	COG0071	Belongs to the small heat shock protein (HSP20) family
FY134_RS24510	COG0577	efflux transmembrane transporter activity
FY134_RS24525	COG3734	2-keto-3-deoxy-galactonokinase
FY134_RS24530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_RS24535	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_RS24545	COG1175	transmembrane transport
FY134_RS24550	COG0395	ABC-type sugar transport system, permease component
FY134_RS24555	COG3842	ATPase activity
FY134_RS24560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY134_RS24565	COG1414	Transcriptional regulator
FY134_RS24570	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS24575	COG3158	transport of potassium into the cell
FY134_RS24585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY134_RS24600	COG2826	transposase and inactivated derivatives, IS30 family
FY134_RS24620	COG0504	CTP synthase activity
FY134_RS24625	COG0006	proline dipeptidase activity
FY134_RS24630	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_RS24635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY134_RS24645	COG0765	amino acid transport
FY134_RS24650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS24695	COG0753	catalase activity
FY134_RS24710	COG3685	Protein conserved in bacteria
FY134_RS24720	COG1309	transcriptional regulator
FY134_RS24725	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FY134_RS24730	COG2080	2 iron, 2 sulfur cluster binding
FY134_RS24735	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FY134_RS24740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY134_RS24790	COG0784	Response regulator, receiver
FY134_RS24790	COG4191	Histidine kinase
FY134_RS24795	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FY134_RS24810	COG1278	Cold shock
FY134_RS24875	COG3920	Histidine kinase
FY134_RS24920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY134_RS24930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY134_RS24940	COG1566	PFAM secretion protein HlyD family protein
FY134_RS24960	COG2207	Transcriptional regulator
FY134_RS24985	COG1192	Involved in chromosome partitioning
FY134_RS24990	COG1475	DNA binding
FY134_RS24995	COG0640	Transcriptional regulator
FY134_RS25000	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY134_RS25045	COG0583	DNA-binding transcription factor activity
FY134_RS25055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_RS25060	COG1116	anion transmembrane transporter activity
FY134_RS25065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_RS25075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS25080	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS25110	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS25115	COG1129	ABC transporter
FY134_RS25140	COG4172	Belongs to the ABC transporter superfamily
FY134_RS25145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS25150	COG0601	transmembrane transport
FY134_RS25160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS25165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_RS25170	COG0583	DNA-binding transcription factor activity
FY134_RS25180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY134_RS25195	COG1132	(ABC) transporter
FY134_RS25200	COG4172	Belongs to the ABC transporter superfamily
FY134_RS25205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS25225	COG1082	Xylose isomerase domain protein TIM barrel
FY134_RS25230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY134_RS25235	COG0019	diaminopimelate decarboxylase activity
FY134_RS25245	COG1475	DNA binding
FY134_RS25255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY134_RS25350	COG1475	DNA binding
FY134_RS25375	COG2824	Alkylphosphonate utilization operon protein PhnA
FY134_RS25420	COG5489	Protein of unknown function (DUF736)
FY134_RS25510	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY134_RS25520	COG0747	negative chemotaxis
FY134_RS25525	COG0444	Belongs to the ABC transporter superfamily
FY134_RS25540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS25545	COG0584	glycerophosphoryl diester phosphodiesterase
FY134_RS25550	COG0483	inositol monophosphate 1-phosphatase activity
FY134_RS25615	COG3161	chorismate lyase activity
FY134_RS25840	COG2222	sugar isomerase
FY134_RS25850	COG0006	proline dipeptidase activity
FY134_RS25870	COG1177	transmembrane transport
FY134_RS25875	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY134_RS25880	COG3842	ATPase activity
FY134_RS25910	COG3842	ATPase activity
FY134_RS25915	COG0006	proline dipeptidase activity
FY134_RS25935	COG0300	oxidoreductase activity
FY134_RS25940	COG0129	dihydroxy-acid dehydratase activity
FY134_RS25945	COG0667	Aldo Keto reductase
FY134_RS25955	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS25965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS25970	COG0601	transmembrane transport
FY134_RS25975	COG4172	Belongs to the ABC transporter superfamily
FY134_RS25985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_RS26020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_RS26055	COG3701	Conjugal transfer protein
FY134_RS26060	COG3846	protein secretion by the type IV secretion system
FY134_RS26070	COG5314	conjugation
FY134_RS26075	COG3451	type IV secretory pathway VirB4
FY134_RS26090	COG4962	Type ii secretion system protein e
FY134_RS26100	COG1192	Involved in chromosome partitioning
FY134_RS26105	COG1475	DNA binding
FY134_RS26110	COG0640	Transcriptional regulator
FY134_RS26175	COG3621	Patatin-like phospholipase
FY134_RS26200	COG1802	Transcriptional regulator
FY134_RS26205	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY134_RS26210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_RS26215	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FY134_RS26225	COG3971	2-oxopent-4-enoate hydratase activity
FY134_RS26230	COG3485	protocatechuate 3,4-dioxygenase
FY134_RS26235	COG0683	leucine binding
FY134_RS26260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_RS26270	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY134_RS26275	COG3959	Transketolase, thiamine diphosphate binding domain
FY134_RS26280	COG3958	Transketolase
FY134_RS26290	COG1063	alcohol dehydrogenase
FY134_RS26295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY134_RS26305	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS26320	COG1802	Transcriptional regulator
FY134_RS26330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_RS26345	COG2186	Transcriptional regulator
FY134_RS26355	COG1126	abc transporter atp-binding protein
FY134_RS26365	COG0765	amino acid transport
FY134_RS26370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_RS26385	COG0436	Aminotransferase
FY134_RS26390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_RS26410	COG1609	Transcriptional regulator
FY134_RS26415	COG0673	inositol 2-dehydrogenase activity
FY134_RS26425	COG0673	inositol 2-dehydrogenase activity
FY134_RS26440	COG3718	enzyme involved in inositol metabolism
FY134_RS26450	COG3962	Belongs to the TPP enzyme family
FY134_RS26455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_RS26465	COG0673	inositol 2-dehydrogenase activity
FY134_RS26470	COG1082	Xylose isomerase domain protein TIM barrel
FY134_RS26480	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_RS26485	COG1129	ABC transporter
FY134_RS26495	COG1609	Transcriptional regulator
FY134_RS26500	COG1309	transcriptional regulator
FY134_RS26505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_RS26530	COG0626	cystathionine gamma-synthase activity
FY134_RS26555	COG4598	ABC transporter
FY134_RS26560	COG0583	DNA-binding transcription factor activity
FY134_RS26570	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY134_RS26640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_RS26645	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS26665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_RS26670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY134_RS26695	COG1126	abc transporter atp-binding protein
FY134_RS26715	COG1960	acyl-CoA dehydrogenase activity
FY134_RS26725	COG1309	transcriptional regulator
FY134_RS26745	COG1137	ATPase activity
FY134_RS26765	COG3485	protocatechuate 3,4-dioxygenase
FY134_RS26780	COG1309	transcriptional regulator
FY134_RS26800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY134_RS26815	COG1960	acyl-CoA dehydrogenase activity
FY134_RS26835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY134_RS26870	COG0583	DNA-binding transcription factor activity
FY134_RS26905	COG0708	Exodeoxyribonuclease III
FY134_RS26930	COG0587	DNA-directed DNA polymerase activity
FY134_RS26950	COG5489	Protein of unknown function (DUF736)
FY134_RS26955	COG4974	Belongs to the 'phage' integrase family
FY134_RS26975	COG0494	nUDIX hydrolase
FY134_RS27000	COG0776	regulation of translation
FY134_RS27005	COG3831	ATPase activity
FY134_RS27070	COG0395	ABC-type sugar transport system, permease component
FY134_RS27075	COG1175	transmembrane transport
FY134_RS27110	COG0640	Transcriptional regulator
FY134_RS27115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY134_RS27120	COG1335	isochorismatase
FY134_RS27130	COG3836	Belongs to the HpcH HpaI aldolase family
FY134_RS27135	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_RS27155	COG0436	Aminotransferase
FY134_RS27170	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY134_RS27195	COG1012	belongs to the aldehyde dehydrogenase family
FY134_RS27200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FY134_RS27240	COG3701	Conjugal transfer protein
FY134_RS27245	COG3846	protein secretion by the type IV secretion system
FY134_RS27255	COG5314	conjugation
FY134_RS27260	COG3451	type IV secretory pathway VirB4
FY134_RS27275	COG4962	Type ii secretion system protein e
FY134_RS27285	COG1192	Involved in chromosome partitioning
FY134_RS27290	COG1475	DNA binding
FY134_RS27295	COG0640	Transcriptional regulator
FY134_RS27305	COG1473	amidohydrolase
FY134_RS27370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY134_RS27415	COG3620	sequence-specific DNA binding
FY134_RS27420	COG3550	peptidyl-serine autophosphorylation
FY134_RS27445	COG2390	Transcriptional regulator
FY134_RS27445	COG4584	PFAM Integrase catalytic
FY134_RS27450	COG4584	PFAM Integrase catalytic
FY134_RS27450	COG2390	Transcriptional regulator
FY134_RS27465	COG1858	cytochrome C peroxidase
FY134_RS27475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FY134_RS27480	COG0583	DNA-binding transcription factor activity
FY134_RS27490	COG1733	regulation of RNA biosynthetic process
FY134_RS27510	COG1196	nuclear chromosome segregation
FY134_RS27510	COG0741	lytic transglycosylase activity
FY134_RS27510	COG0739	heme binding
FY134_RS27525	COG3451	type IV secretory pathway VirB4
FY134_RS27555	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY134_RS27570	COG1192	Involved in chromosome partitioning
FY134_RS27575	COG3505	Type IV secretory pathway VirD4
FY134_RS27680	COG3436	PFAM IS66 Orf2 family protein
FY134_RS27690	COG1940	carbohydrate kinase activity
FY134_RS27695	COG1653	transport
FY134_RS27700	COG1175	transmembrane transport
FY134_RS27705	COG0395	ABC-type sugar transport system, permease component
FY134_RS27720	COG3842	ATPase activity
FY134_RS27725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY134_RS27745	COG3831	ATPase activity
FY134_RS27830	COG3701	Conjugal transfer protein
FY134_RS27835	COG3846	protein secretion by the type IV secretion system
FY134_RS27845	COG5314	conjugation
FY134_RS27850	COG3451	type IV secretory pathway VirB4
FY134_RS27865	COG4962	Type ii secretion system protein e