locus-tag	class	description
KXJ62_RS00005	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KXJ62_RS00010	COG0424	maF-like protein
KXJ62_RS00015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KXJ62_RS00020	COG0237	dephospho-CoA kinase activity
KXJ62_RS00030	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KXJ62_RS00035	COG3030	protein affecting phage T7 exclusion by the F plasmid
KXJ62_RS00045	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KXJ62_RS00070	COG0179	Fumarylacetoacetate (FAA) hydrolase
KXJ62_RS00085	COG0135	phosphoribosylanthranilate isomerase activity
KXJ62_RS00090	COG0133	tryptophan synthase activity
KXJ62_RS00095	COG0159	tryptophan synthase activity
KXJ62_RS00100	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KXJ62_RS00125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KXJ62_RS00135	COG2205	protein histidine kinase activity
KXJ62_RS00140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KXJ62_RS00145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KXJ62_RS00150	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KXJ62_RS00150	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KXJ62_RS00155	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KXJ62_RS00160	COG0642	Histidine kinase
KXJ62_RS00165	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS00170	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KXJ62_RS00180	COG1072	(Pantothenic acid kinase))
KXJ62_RS00185	COG0140	phosphoribosyl-ATP diphosphatase activity
KXJ62_RS00190	COG0107	imidazoleglycerol-phosphate synthase activity
KXJ62_RS00195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KXJ62_RS00200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KXJ62_RS00210	COG0131	Imidazoleglycerol-phosphate dehydratase
KXJ62_RS00215	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KXJ62_RS00220	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KXJ62_RS00230	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KXJ62_RS00245	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KXJ62_RS00255	COG1643	Atp-dependent helicase
KXJ62_RS00290	COG0514	ATP-dependent DNA helicase (RecQ)
KXJ62_RS00315	COG1072	(Pantothenic acid kinase))
KXJ62_RS00325	COG1780	Probably involved in ribonucleotide reductase function
KXJ62_RS00345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KXJ62_RS00375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ62_RS00385	COG2813	Specifically methylates the guanine in position
KXJ62_RS00390	COG1185	polyribonucleotide nucleotidyltransferase activity
KXJ62_RS00395	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KXJ62_RS00400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KXJ62_RS00405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KXJ62_RS00410	COG3064	Membrane
KXJ62_RS00410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KXJ62_RS00425	COG0779	Required for maturation of 30S ribosomal subunits
KXJ62_RS00430	COG2814	Major facilitator Superfamily
KXJ62_RS00435	COG2951	lytic endotransglycosylase activity
KXJ62_RS00440	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KXJ62_RS00450	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KXJ62_RS00455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KXJ62_RS00470	COG2816	NAD+ diphosphatase activity
KXJ62_RS00475	COG0077	Prephenate dehydratase
KXJ62_RS00475	COG1605	Chorismate mutase
KXJ62_RS00480	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KXJ62_RS00485	COG3474	cytochrome
KXJ62_RS00495	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KXJ62_RS00500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KXJ62_RS00505	COG1278	Cold shock
KXJ62_RS00510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KXJ62_RS00525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KXJ62_RS00525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KXJ62_RS00535	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KXJ62_RS00565	COG2900	Belongs to the SlyX family
KXJ62_RS00575	COG0484	heat shock protein binding
KXJ62_RS00580	COG0443	Heat shock 70 kDa protein
KXJ62_RS00595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KXJ62_RS00600	COG1744	ABC transporter substrate-binding protein PnrA-like
KXJ62_RS00605	COG3845	ABC transporter
KXJ62_RS00610	COG1079	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS00615	COG1079	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS00620	COG0295	cytidine deaminase activity
KXJ62_RS00625	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KXJ62_RS00630	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KXJ62_RS00635	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KXJ62_RS00645	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KXJ62_RS00650	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KXJ62_RS00655	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KXJ62_RS00665	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KXJ62_RS00670	COG1845	cytochrome c oxidase, subunit III
KXJ62_RS00675	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KXJ62_RS00685	COG0477	Major facilitator Superfamily
KXJ62_RS00690	COG0070	glutamate synthase
KXJ62_RS00690	COG0069	glutamate synthase activity
KXJ62_RS00690	COG0067	glutamate synthase
KXJ62_RS00695	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KXJ62_RS00710	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KXJ62_RS00720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KXJ62_RS00750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ62_RS00770	COG0848	biopolymer transport protein
KXJ62_RS00780	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KXJ62_RS00795	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KXJ62_RS00800	COG3454	Phosphonate metabolism
KXJ62_RS00805	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KXJ62_RS00810	COG3639	organic phosphonate transmembrane transporter activity
KXJ62_RS00815	COG3639	organic phosphonate transmembrane transporter activity
KXJ62_RS00820	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KXJ62_RS00825	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KXJ62_RS00835	COG4778	phosphonate C-P lyase system protein PhnL
KXJ62_RS00840	COG4107	phosphonate C-P lyase system protein PhnK
KXJ62_RS00845	COG3627	carbon phosphorus lyase activity
KXJ62_RS00850	COG3626	phosphonate metabolism
KXJ62_RS00855	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
KXJ62_RS00860	COG3624	Phosphonate C-P lyase system protein PhnG
KXJ62_RS00865	COG2188	Transcriptional regulator
KXJ62_RS00870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KXJ62_RS00875	COG0837	glucose binding
KXJ62_RS00880	COG1803	Methylglyoxal synthase
KXJ62_RS00885	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KXJ62_RS00890	COG4166	transmembrane transport
KXJ62_RS00895	COG4174	ABC transporter (Permease)
KXJ62_RS00900	COG4239	(ABC) transporter, permease
KXJ62_RS00905	COG4172	Belongs to the ABC transporter superfamily
KXJ62_RS00915	COG0174	glutamine synthetase
KXJ62_RS00920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS00925	COG3265	gluconokinase activity
KXJ62_RS00930	COG1174	glycine betaine transport
KXJ62_RS00935	COG1125	glycine betaine transport
KXJ62_RS00940	COG1174	glycine betaine transport
KXJ62_RS00945	COG1732	Glycine betaine
KXJ62_RS00955	COG1959	2 iron, 2 sulfur cluster binding
KXJ62_RS00960	COG1840	ABC-type Fe3 transport system, periplasmic component
KXJ62_RS00970	COG4269	membrane
KXJ62_RS00990	COG0697	spore germination
KXJ62_RS01005	COG0791	NLP P60 protein
KXJ62_RS01015	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KXJ62_RS01020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KXJ62_RS01055	COG4964	Belongs to the GSP D family
KXJ62_RS01100	COG3422	double-strand break repair
KXJ62_RS01105	COG3757	hydrolase, family 25
KXJ62_RS01110	COG0697	spore germination
KXJ62_RS01115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KXJ62_RS01145	COG0481	GTPase activity
KXJ62_RS01150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KXJ62_RS01165	COG1396	sequence-specific DNA binding
KXJ62_RS01180	COG1917	Cupin 2, conserved barrel domain protein
KXJ62_RS01180	COG2169	Transcriptional regulator
KXJ62_RS01185	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KXJ62_RS01210	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KXJ62_RS01215	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KXJ62_RS01220	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KXJ62_RS01230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KXJ62_RS01235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KXJ62_RS01235	COG0072	phenylalanine-tRNA ligase activity
KXJ62_RS01240	COG0667	Aldo Keto reductase
KXJ62_RS01255	COG0667	Aldo Keto reductase
KXJ62_RS01260	COG4977	sequence-specific DNA binding
KXJ62_RS01285	COG1570	exodeoxyribonuclease VII activity
KXJ62_RS01290	COG4948	Mandelate Racemase Muconate Lactonizing
KXJ62_RS01300	COG1846	Transcriptional regulator
KXJ62_RS01305	COG0697	spore germination
KXJ62_RS01310	COG2309	aminopeptidase activity
KXJ62_RS01315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KXJ62_RS01320	COG1393	Belongs to the ArsC family
KXJ62_RS01335	COG1309	transcriptional regulator
KXJ62_RS01345	COG0519	Catalyzes the synthesis of GMP from XMP
KXJ62_RS01345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KXJ62_RS01360	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KXJ62_RS01390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KXJ62_RS01400	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KXJ62_RS01410	COG1968	undecaprenyl-diphosphatase activity
KXJ62_RS01430	COG0284	orotidine-5'-phosphate decarboxylase activity
KXJ62_RS01440	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KXJ62_RS01450	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KXJ62_RS01455	COG0792	nuclease activity
KXJ62_RS01470	COG1175	transmembrane transport
KXJ62_RS01475	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS01480	COG3842	ATPase activity
KXJ62_RS01490	COG0189	ligase activity
KXJ62_RS01495	COG0606	chelatase, subunit chli
KXJ62_RS01500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KXJ62_RS01505	COG1280	lysine exporter protein (LysE YggA)
KXJ62_RS01510	COG0756	dUTP diphosphatase activity
KXJ62_RS01515	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KXJ62_RS01520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KXJ62_RS01535	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KXJ62_RS01540	COG2226	methyltransferase
KXJ62_RS01545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KXJ62_RS01550	COG1024	Enoyl-CoA hydratase
KXJ62_RS01555	COG0268	Binds directly to 16S ribosomal RNA
KXJ62_RS01560	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KXJ62_RS01565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KXJ62_RS01570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KXJ62_RS01575	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KXJ62_RS01580	COG1420	regulation of RNA biosynthetic process
KXJ62_RS01585	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KXJ62_RS01590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KXJ62_RS01595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KXJ62_RS01605	COG1137	ATPase activity
KXJ62_RS01610	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KXJ62_RS01620	COG0616	signal peptide processing
KXJ62_RS01625	COG0776	regulation of translation
KXJ62_RS01640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KXJ62_RS01645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KXJ62_RS01660	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KXJ62_RS01665	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KXJ62_RS01670	COG0728	peptidoglycan biosynthetic process
KXJ62_RS01680	COG0180	Tryptophanyl-tRNA synthetase
KXJ62_RS01690	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KXJ62_RS01715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KXJ62_RS01720	COG1702	phosphate starvation-inducible protein PhoH
KXJ62_RS01725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KXJ62_RS01735	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KXJ62_RS01740	COG1396	sequence-specific DNA binding
KXJ62_RS01745	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KXJ62_RS01750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KXJ62_RS01755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ62_RS01765	COG0242	peptide deformylase activity
KXJ62_RS01770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KXJ62_RS01775	COG0101	tRNA pseudouridine synthase activity
KXJ62_RS01785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KXJ62_RS01790	COG2171	N-acyltransferase activity
KXJ62_RS01800	COG0840	transmembrane signaling receptor activity
KXJ62_RS01810	COG0071	Belongs to the small heat shock protein (HSP20) family
KXJ62_RS01835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KXJ62_RS01845	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KXJ62_RS01850	COG0706	membrane insertase activity
KXJ62_RS01855	COG0594	ribonuclease P activity
KXJ62_RS01860	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KXJ62_RS01865	COG0840	transmembrane signaling receptor activity
KXJ62_RS01870	COG3850	Histidine kinase
KXJ62_RS01870	COG5002	protein histidine kinase activity
KXJ62_RS01880	COG2226	methyltransferase
KXJ62_RS01885	COG3842	ATPase activity
KXJ62_RS01890	COG1175	transmembrane transport
KXJ62_RS01895	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS01910	COG0427	acetyl-CoA hydrolase
KXJ62_RS01920	COG3938	Belongs to the proline racemase family
KXJ62_RS01925	COG0418	dihydroorotase activity
KXJ62_RS01930	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KXJ62_RS01950	COG0166	Belongs to the GPI family
KXJ62_RS01955	COG0318	PFAM AMP-dependent synthetase and ligase
KXJ62_RS01960	COG3842	ATPase activity
KXJ62_RS01965	COG1840	ABC-type Fe3 transport system, periplasmic component
KXJ62_RS01970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KXJ62_RS01975	COG4774	siderophore transport
KXJ62_RS02015	COG2326	polyphosphate kinase activity
KXJ62_RS02020	COG5002	protein histidine kinase activity
KXJ62_RS02025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KXJ62_RS02030	COG0573	inorganic phosphate transmembrane transporter activity
KXJ62_RS02040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KXJ62_RS02045	COG0704	Plays a role in the regulation of phosphate uptake
KXJ62_RS02050	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS02060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KXJ62_RS02065	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KXJ62_RS02075	COG2967	ApaG domain
KXJ62_RS02085	COG0717	Belongs to the dCTP deaminase family
KXJ62_RS02325	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KXJ62_RS02345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KXJ62_RS02400	COG0167	dihydroorotate dehydrogenase activity
KXJ62_RS02415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KXJ62_RS02435	COG1959	2 iron, 2 sulfur cluster binding
KXJ62_RS02440	COG1201	RNA secondary structure unwinding
KXJ62_RS02460	COG0730	response to heat
KXJ62_RS02470	COG1960	acyl-CoA dehydrogenase activity
KXJ62_RS02475	COG0183	Belongs to the thiolase family
KXJ62_RS02480	COG1250	3-hydroxyacyl-CoA dehydrogenase
KXJ62_RS02480	COG1024	Enoyl-CoA hydratase
KXJ62_RS02500	COG1320	monovalent cation:proton antiporter activity
KXJ62_RS02505	COG2212	antiporter activity
KXJ62_RS02510	COG1863	multisubunit Na H antiporter MnhE subunit
KXJ62_RS02515	COG0651	ATP synthesis coupled electron transport
KXJ62_RS02520	COG1006	Multisubunit Na H antiporter MnhC subunit
KXJ62_RS02525	COG2111	Na H antiporter
KXJ62_RS02525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KXJ62_RS02535	COG0840	transmembrane signaling receptor activity
KXJ62_RS02545	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS02550	COG2198	Histidine kinase
KXJ62_RS02550	COG0643	Histidine kinase
KXJ62_RS02555	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KXJ62_RS02560	COG2201	protein-glutamate methylesterase activity
KXJ62_RS02565	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS02570	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KXJ62_RS02580	COG1766	The M ring may be actively involved in energy transduction
KXJ62_RS02585	COG2771	luxR family
KXJ62_RS02595	COG0840	transmembrane signaling receptor activity
KXJ62_RS02595	COG2972	Histidine kinase
KXJ62_RS02600	COG2205	protein histidine kinase activity
KXJ62_RS02600	COG0784	Response regulator, receiver
KXJ62_RS02600	COG2198	Histidine kinase
KXJ62_RS02605	COG1970	mechanosensitive ion channel activity
KXJ62_RS02610	COG0436	Aminotransferase
KXJ62_RS02625	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KXJ62_RS02630	COG0424	maF-like protein
KXJ62_RS02635	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KXJ62_RS02645	COG5328	Belongs to the UPF0262 family
KXJ62_RS02650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KXJ62_RS02660	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KXJ62_RS02675	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KXJ62_RS02695	COG1338	Plays a role in the flagellum-specific transport system
KXJ62_RS02705	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KXJ62_RS02715	COG1706	bacterial-type flagellum-dependent cell motility
KXJ62_RS02720	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KXJ62_RS02725	COG4786	Flagellar basal body rod
KXJ62_RS02730	COG1677	Flagellar hook-basal body complex protein FliE
KXJ62_RS02735	COG1558	bacterial-type flagellum-dependent cell motility
KXJ62_RS02740	COG1815	bacterial-type flagellum-dependent cell motility
KXJ62_RS02750	COG1157	protein secretion by the type III secretion system
KXJ62_RS02755	COG4786	Flagellar basal body rod
KXJ62_RS02765	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KXJ62_RS02770	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KXJ62_RS02775	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KXJ62_RS02780	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KXJ62_RS02785	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KXJ62_RS02805	COG1360	Flagellar Motor Protein
KXJ62_RS02830	COG1749	Flagellar hook protein flgE
KXJ62_RS02850	COG5443	negative regulation of bacterial-type flagellum assembly
KXJ62_RS02855	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KXJ62_RS02865	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KXJ62_RS02905	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KXJ62_RS02910	COG1609	Transcriptional regulator
KXJ62_RS02915	COG1653	transport
KXJ62_RS02920	COG1175	transmembrane transport
KXJ62_RS02925	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS02930	COG0366	Alpha amylase catalytic
KXJ62_RS02935	COG3842	ATPase activity
KXJ62_RS02950	COG0129	dihydroxy-acid dehydratase activity
KXJ62_RS02955	COG0363	glucosamine-6-phosphate deaminase activity
KXJ62_RS02960	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KXJ62_RS02965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS02975	COG2081	HI0933 family
KXJ62_RS02990	COG2224	Isocitrate lyase
KXJ62_RS03005	COG3842	ATPase activity
KXJ62_RS03010	COG1176	ABC-type spermidine putrescine transport system, permease component I
KXJ62_RS03015	COG1177	transmembrane transport
KXJ62_RS03025	COG2205	protein histidine kinase activity
KXJ62_RS03035	COG0248	Ppx GppA phosphatase
KXJ62_RS03040	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KXJ62_RS03045	COG0477	Major facilitator Superfamily
KXJ62_RS03090	COG0521	Mo-molybdopterin cofactor biosynthetic process
KXJ62_RS03095	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KXJ62_RS03105	COG0142	geranyltranstransferase activity
KXJ62_RS03130	COG0752	glycyl-tRNA synthetase alpha subunit
KXJ62_RS03140	COG1704	LemA family
KXJ62_RS03145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KXJ62_RS03155	COG0751	glycine-tRNA ligase activity
KXJ62_RS03160	COG1683	Conserved Protein
KXJ62_RS03165	COG0840	transmembrane signaling receptor activity
KXJ62_RS03175	COG0151	Belongs to the GarS family
KXJ62_RS03180	COG2183	response to ionizing radiation
KXJ62_RS03185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KXJ62_RS03195	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KXJ62_RS03210	COG0583	DNA-binding transcription factor activity
KXJ62_RS03230	COG0306	phosphate transporter
KXJ62_RS03240	COG0561	phosphatase activity
KXJ62_RS03245	COG0438	transferase activity, transferring glycosyl groups
KXJ62_RS03250	COG2186	Transcriptional regulator
KXJ62_RS03260	COG0583	DNA-binding transcription factor activity
KXJ62_RS03265	COG0277	FAD linked oxidase domain protein
KXJ62_RS03270	COG0277	FAD linked oxidase domain protein
KXJ62_RS03275	COG0247	lactate metabolic process
KXJ62_RS03285	COG1376	ErfK ybiS ycfS ynhG family protein
KXJ62_RS03290	COG0519	Catalyzes the synthesis of GMP from XMP
KXJ62_RS03300	COG2855	membrane
KXJ62_RS03305	COG0583	DNA-binding transcription factor activity
KXJ62_RS03325	COG0124	histidyl-tRNA synthetase
KXJ62_RS03335	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KXJ62_RS03340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KXJ62_RS03345	COG2259	Doxx family
KXJ62_RS03355	COG0459	protein refolding
KXJ62_RS03360	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KXJ62_RS03370	COG0196	riboflavin kinase activity
KXJ62_RS03375	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KXJ62_RS03385	COG0590	tRNA wobble adenosine to inosine editing
KXJ62_RS03390	COG1187	pseudouridine synthase activity
KXJ62_RS03395	COG0742	ribosomal rna small subunit methyltransferase
KXJ62_RS03400	COG1752	Esterase of the alpha-beta hydrolase superfamily
KXJ62_RS03410	COG0312	modulator of DNA gyrase
KXJ62_RS03415	COG0483	inositol monophosphate 1-phosphatase activity
KXJ62_RS03435	COG1663	tetraacyldisaccharide 4'-kinase activity
KXJ62_RS03445	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KXJ62_RS03455	COG3300	MHYT domain
KXJ62_RS03455	COG5001	Diguanylate cyclase
KXJ62_RS03460	COG3386	PFAM SMP-30 Gluconolaconase
KXJ62_RS03465	COG0800	Aldolase
KXJ62_RS03470	COG3734	2-keto-3-deoxy-galactonokinase
KXJ62_RS03475	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS03485	COG2197	response regulator
KXJ62_RS03490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KXJ62_RS03500	COG0598	Magnesium transport protein CorA
KXJ62_RS03505	COG3158	transport of potassium into the cell
KXJ62_RS03520	COG0356	it plays a direct role in the translocation of protons across the membrane
KXJ62_RS03530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KXJ62_RS03535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KXJ62_RS03550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KXJ62_RS03570	COG0009	L-threonylcarbamoyladenylate synthase
KXJ62_RS03580	COG4638	Rieske (2fe-2S)
KXJ62_RS03605	COG1960	acyl-CoA dehydrogenase activity
KXJ62_RS03620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KXJ62_RS03625	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KXJ62_RS03630	COG0840	transmembrane signaling receptor activity
KXJ62_RS03670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KXJ62_RS03675	COG1741	Belongs to the pirin family
KXJ62_RS03680	COG1722	exodeoxyribonuclease VII activity
KXJ62_RS03685	COG0123	including yeast histone deacetylase and acetoin utilization protein
KXJ62_RS03690	COG1268	BioY protein
KXJ62_RS03695	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KXJ62_RS03700	COG1122	ATPase activity
KXJ62_RS03705	COG3214	Protein conserved in bacteria
KXJ62_RS03710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KXJ62_RS03710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KXJ62_RS03715	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KXJ62_RS03735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KXJ62_RS03750	COG0259	pyridoxamine-phosphate oxidase activity
KXJ62_RS03765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KXJ62_RS03775	COG0312	modulator of DNA gyrase
KXJ62_RS03790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KXJ62_RS03795	COG0109	protoheme IX farnesyltransferase activity
KXJ62_RS03800	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KXJ62_RS03815	COG3346	SURF1 family
KXJ62_RS03820	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KXJ62_RS03825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KXJ62_RS03830	COG0328	RNA-DNA hybrid ribonuclease activity
KXJ62_RS03845	COG0678	peroxiredoxin activity
KXJ62_RS03845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KXJ62_RS03855	COG1678	Uncharacterized ACR, COG1678
KXJ62_RS03875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KXJ62_RS03880	COG0612	Peptidase, M16
KXJ62_RS03895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KXJ62_RS03900	COG1802	Transcriptional regulator
KXJ62_RS03915	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KXJ62_RS03930	COG1194	a g-specific adenine glycosylase
KXJ62_RS03940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KXJ62_RS03945	COG1196	nuclear chromosome segregation
KXJ62_RS03950	COG2514	catechol 2,3-dioxygenase activity
KXJ62_RS03955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KXJ62_RS03955	COG0574	Belongs to the PEP-utilizing enzyme family
KXJ62_RS03970	COG1823	symporter activity
KXJ62_RS04000	COG0579	oxidoreductase
KXJ62_RS04015	COG2895	sulfate adenylyltransferase (ATP) activity
KXJ62_RS04020	COG0175	sulfate reduction
KXJ62_RS04025	COG0175	sulfate reduction
KXJ62_RS04030	COG1959	2 iron, 2 sulfur cluster binding
KXJ62_RS04035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KXJ62_RS04040	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KXJ62_RS04045	COG4208	sulfate ABC transporter
KXJ62_RS04050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KXJ62_RS04060	COG2200	EAL domain
KXJ62_RS04060	COG2199	diguanylate cyclase activity
KXJ62_RS04060	COG2203	Gaf domain
KXJ62_RS04070	COG1309	transcriptional regulator
KXJ62_RS04075	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS04080	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KXJ62_RS04125	COG0477	Major facilitator Superfamily
KXJ62_RS04135	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KXJ62_RS04135	COG1793	dna ligase
KXJ62_RS04155	COG1376	ErfK ybiS ycfS ynhG family protein
KXJ62_RS04160	COG1376	ErfK ybiS ycfS ynhG family protein
KXJ62_RS04165	COG1846	Transcriptional regulator
KXJ62_RS04170	COG1764	response to oxidative stress
KXJ62_RS04185	COG0488	(ABC) transporter
KXJ62_RS04220	COG4221	oxidoreductase activity
KXJ62_RS04235	COG0433	COG0433 Predicted ATPase
KXJ62_RS04245	COG1733	regulation of RNA biosynthetic process
KXJ62_RS04250	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KXJ62_RS04265	COG0656	L-ascorbic acid biosynthetic process
KXJ62_RS04270	COG2378	regulation of single-species biofilm formation
KXJ62_RS04280	COG4106	trans-aconitate 2-methyltransferase activity
KXJ62_RS04285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KXJ62_RS04290	COG0840	transmembrane signaling receptor activity
KXJ62_RS04295	COG0583	DNA-binding transcription factor activity
KXJ62_RS04310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KXJ62_RS04320	COG2378	regulation of single-species biofilm formation
KXJ62_RS04330	COG3909	cytochrome
KXJ62_RS04335	COG2010	Cytochrome c
KXJ62_RS04365	COG0789	Transcriptional regulator
KXJ62_RS04390	COG4175	Glycine betaine
KXJ62_RS04390	COG0517	IMP dehydrogenase activity
KXJ62_RS04395	COG4176	ABC-type proline glycine betaine transport system permease component
KXJ62_RS04420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ62_RS04430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KXJ62_RS04430	COG2169	Transcriptional regulator
KXJ62_RS04440	COG2514	catechol 2,3-dioxygenase activity
KXJ62_RS04460	COG1272	protein, Hemolysin III
KXJ62_RS04470	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KXJ62_RS04475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KXJ62_RS04475	COG2111	Na H antiporter
KXJ62_RS04480	COG2111	Na H antiporter
KXJ62_RS04485	COG1006	Multisubunit Na H antiporter MnhC subunit
KXJ62_RS04490	COG0651	ATP synthesis coupled electron transport
KXJ62_RS04495	COG1863	multisubunit Na H antiporter MnhE subunit
KXJ62_RS04500	COG2212	antiporter activity
KXJ62_RS04505	COG1320	monovalent cation:proton antiporter activity
KXJ62_RS04510	COG4957	zinc ion binding
KXJ62_RS04525	COG2166	iron-sulfur cluster assembly
KXJ62_RS04535	COG2205	protein histidine kinase activity
KXJ62_RS04590	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KXJ62_RS04595	COG2983	Belongs to the UPF0260 family
KXJ62_RS04605	COG3041	Addiction module toxin RelE StbE family
KXJ62_RS04610	COG3077	Addiction module antitoxin, RelB DinJ family
KXJ62_RS04640	COG2337	Toxic component of a toxin-antitoxin (TA) module
KXJ62_RS04650	COG2814	Major facilitator Superfamily
KXJ62_RS04660	COG1621	beta-fructofuranosidase activity
KXJ62_RS04665	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KXJ62_RS04715	COG4695	Portal protein
KXJ62_RS04830	COG4235	cytochrome complex assembly
KXJ62_RS04835	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KXJ62_RS04840	COG1138	Cytochrome C-type biogenesis protein
KXJ62_RS04845	COG3088	subunit of a heme lyase
KXJ62_RS04850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KXJ62_RS04860	COG2205	protein histidine kinase activity
KXJ62_RS04865	COG3713	MltA-interacting MipA family protein
KXJ62_RS04870	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KXJ62_RS04875	COG2205	protein histidine kinase activity
KXJ62_RS04875	COG2202	Pas domain
KXJ62_RS04885	COG0308	aminopeptidase N
KXJ62_RS04890	COG0697	spore germination
KXJ62_RS04905	COG0443	Heat shock 70 kDa protein
KXJ62_RS04945	COG0604	alcohol dehydrogenase
KXJ62_RS04950	COG1733	regulation of RNA biosynthetic process
KXJ62_RS04955	COG1968	undecaprenyl-diphosphatase activity
KXJ62_RS04960	COG2239	Acts as a magnesium transporter
KXJ62_RS04965	COG2814	Major facilitator Superfamily
KXJ62_RS04995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KXJ62_RS05025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KXJ62_RS05075	COG0741	lytic transglycosylase activity
KXJ62_RS05080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ62_RS05085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KXJ62_RS05090	COG0840	transmembrane signaling receptor activity
KXJ62_RS05100	COG1758	RNA polymerase activity
KXJ62_RS05120	COG0736	holo-[acyl-carrier-protein] synthase activity
KXJ62_RS05125	COG0681	Belongs to the peptidase S26 family
KXJ62_RS05130	COG0571	ribonuclease III activity
KXJ62_RS05135	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KXJ62_RS05140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KXJ62_RS05145	COG0784	Response regulator, receiver
KXJ62_RS05150	COG1381	Involved in DNA repair and RecF pathway recombination
KXJ62_RS05160	COG2226	methyltransferase
KXJ62_RS05170	COG1418	mRNA catabolic process
KXJ62_RS05180	COG0346	lactoylglutathione lyase activity
KXJ62_RS05195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ62_RS05200	COG3443	Belongs to the bacterial solute-binding protein 9 family
KXJ62_RS05205	COG0668	transmembrane transport
KXJ62_RS05215	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KXJ62_RS05240	COG1051	belongs to the nudix hydrolase family
KXJ62_RS05245	COG1742	UPF0060 membrane protein
KXJ62_RS05260	COG1183	phosphatidylcholine synthase activity
KXJ62_RS05265	COG0688	phosphatidylethanolamine metabolic process
KXJ62_RS05270	COG5265	(ABC) transporter
KXJ62_RS05275	COG1652	LysM domain
KXJ62_RS05310	COG2852	Protein conserved in bacteria
KXJ62_RS05315	COG0215	cysteine-tRNA ligase activity
KXJ62_RS05320	COG4221	oxidoreductase activity
KXJ62_RS05325	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KXJ62_RS05330	COG1286	toxin biosynthetic process
KXJ62_RS05350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KXJ62_RS05360	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KXJ62_RS05370	COG0305	Participates in initiation and elongation during chromosome replication
KXJ62_RS05390	COG0359	binds to the 23S rRNA
KXJ62_RS05400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KXJ62_RS05405	COG0360	Binds together with S18 to 16S ribosomal RNA
KXJ62_RS05410	COG0667	Aldo Keto reductase
KXJ62_RS05415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KXJ62_RS05425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KXJ62_RS05430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KXJ62_RS05435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KXJ62_RS05440	COG1561	YicC-like family, N-terminal region
KXJ62_RS05445	COG0194	GDP metabolic process
KXJ62_RS05450	COG0400	carboxylic ester hydrolase activity
KXJ62_RS05455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KXJ62_RS05460	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KXJ62_RS05470	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KXJ62_RS05485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KXJ62_RS05505	COG5001	Diguanylate cyclase
KXJ62_RS05505	COG3300	MHYT domain
KXJ62_RS05510	COG4191	Histidine kinase
KXJ62_RS05525	COG0488	(ABC) transporter
KXJ62_RS05530	COG3706	GGDEF domain
KXJ62_RS05540	COG0105	UTP biosynthetic process
KXJ62_RS05560	COG0314	molybdopterin synthase activity
KXJ62_RS05565	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KXJ62_RS05570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KXJ62_RS05575	COG0322	excinuclease ABC activity
KXJ62_RS05580	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS05590	COG0625	glutathione transferase activity
KXJ62_RS05605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KXJ62_RS05610	COG0243	molybdopterin cofactor binding
KXJ62_RS05625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KXJ62_RS05630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KXJ62_RS05635	COG0628	permease
KXJ62_RS05645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KXJ62_RS05650	COG0248	Ppx GppA phosphatase
KXJ62_RS05675	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KXJ62_RS05685	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KXJ62_RS05690	COG0477	Major facilitator Superfamily
KXJ62_RS05695	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KXJ62_RS05705	COG4452	Inner membrane protein CreD
KXJ62_RS05710	COG0659	secondary active sulfate transmembrane transporter activity
KXJ62_RS05720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KXJ62_RS05725	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KXJ62_RS05735	COG0113	porphobilinogen synthase activity
KXJ62_RS05755	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KXJ62_RS05760	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KXJ62_RS05765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KXJ62_RS05765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KXJ62_RS05775	COG1280	lysine exporter protein (LysE YggA)
KXJ62_RS05780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KXJ62_RS05785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KXJ62_RS05790	COG2814	Major facilitator Superfamily
KXJ62_RS05795	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KXJ62_RS05815	COG0416	fatty acid biosynthetic process
KXJ62_RS05820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KXJ62_RS05825	COG0776	regulation of translation
KXJ62_RS05920	COG0601	transmembrane transport
KXJ62_RS05925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS05930	COG0444	Belongs to the ABC transporter superfamily
KXJ62_RS05950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KXJ62_RS05955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KXJ62_RS05970	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KXJ62_RS05975	COG0583	DNA-binding transcription factor activity
KXJ62_RS05980	COG0737	Belongs to the 5'-nucleotidase family
KXJ62_RS06005	COG2897	thiosulfate sulfurtransferase activity
KXJ62_RS06020	COG0415	Belongs to the DNA photolyase family
KXJ62_RS06030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KXJ62_RS06060	COG3932	Exopolysaccharide synthesis, ExoD
KXJ62_RS06115	COG0297	glycogen (starch) synthase activity
KXJ62_RS06140	COG1612	heme a metabolic process
KXJ62_RS06150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KXJ62_RS06155	COG0010	Belongs to the arginase family
KXJ62_RS06160	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KXJ62_RS06165	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KXJ62_RS06175	COG1832	CoA-binding protein
KXJ62_RS06200	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS06205	COG2124	cytochrome p450
KXJ62_RS06210	COG2199	diguanylate cyclase activity
KXJ62_RS06215	COG0740	serine-type endopeptidase activity
KXJ62_RS06220	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KXJ62_RS06225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KXJ62_RS06255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KXJ62_RS06260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KXJ62_RS06265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KXJ62_RS06275	COG0649	NAD binding
KXJ62_RS06285	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KXJ62_RS06290	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KXJ62_RS06300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KXJ62_RS06305	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KXJ62_RS06315	COG0713	ATP synthesis coupled electron transport
KXJ62_RS06330	COG1007	ATP synthesis coupled electron transport
KXJ62_RS06350	COG0442	prolyl-tRNA aminoacylation
KXJ62_RS06360	COG1136	(ABC) transporter
KXJ62_RS06375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KXJ62_RS06385	COG0784	Response regulator, receiver
KXJ62_RS06395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KXJ62_RS06400	COG0477	Major facilitator Superfamily
KXJ62_RS06415	COG0557	exoribonuclease II activity
KXJ62_RS06420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KXJ62_RS06430	COG0758	DNA mediated transformation
KXJ62_RS06435	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KXJ62_RS06445	COG0540	Belongs to the ATCase OTCase family
KXJ62_RS06455	COG1960	acyl-CoA dehydrogenase activity
KXJ62_RS06460	COG0456	acetyltransferase
KXJ62_RS06490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KXJ62_RS06495	COG2824	Alkylphosphonate utilization operon protein PhnA
KXJ62_RS06500	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KXJ62_RS06505	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KXJ62_RS06510	COG0154	amidase activity
KXJ62_RS06515	COG0456	acetyltransferase
KXJ62_RS06520	COG3811	Belongs to the UPF0386 family
KXJ62_RS06535	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KXJ62_RS06545	COG0456	acetyltransferase
KXJ62_RS06560	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KXJ62_RS06565	COG0439	Biotin carboxylase
KXJ62_RS06570	COG0511	ligase activity, forming carbon-carbon bonds
KXJ62_RS06575	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KXJ62_RS06585	COG0436	Aminotransferase
KXJ62_RS06605	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS06610	COG1530	ribonuclease E activity
KXJ62_RS06625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KXJ62_RS06645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KXJ62_RS06650	COG0384	phenazine biosynthesis protein PhzF
KXJ62_RS06670	COG0633	Ferredoxin
KXJ62_RS06680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KXJ62_RS06685	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KXJ62_RS06690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KXJ62_RS06700	COG3768	UPF0283 membrane protein
KXJ62_RS06705	COG3106	COG3106 Predicted ATPase
KXJ62_RS06735	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KXJ62_RS06765	COG0537	adenosine 5'-monophosphoramidase activity
KXJ62_RS06790	COG0052	Belongs to the universal ribosomal protein uS2 family
KXJ62_RS06795	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KXJ62_RS06800	COG0528	UMP kinase activity
KXJ62_RS06805	COG0233	cytoplasmic translational termination
KXJ62_RS06810	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KXJ62_RS06820	COG0750	zinc metalloprotease
KXJ62_RS06825	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KXJ62_RS06830	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KXJ62_RS06835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KXJ62_RS06840	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KXJ62_RS06845	COG3494	Protein of unknown function (DUF1009)
KXJ62_RS06850	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KXJ62_RS06855	COG2186	Transcriptional regulator
KXJ62_RS06865	COG0765	amino acid transport
KXJ62_RS06870	COG0765	amino acid transport
KXJ62_RS06880	COG0372	Belongs to the citrate synthase family
KXJ62_RS06895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KXJ62_RS06900	COG4598	ABC transporter
KXJ62_RS06905	COG0765	amino acid transport
KXJ62_RS06910	COG0765	amino acid transport
KXJ62_RS06915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS06920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KXJ62_RS06930	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS06940	COG2182	Extracellular solute-binding protein
KXJ62_RS06950	COG4948	Mandelate Racemase Muconate Lactonizing
KXJ62_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS06960	COG1063	alcohol dehydrogenase
KXJ62_RS06965	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KXJ62_RS06985	COG0683	leucine binding
KXJ62_RS06990	COG1960	acyl-CoA dehydrogenase activity
KXJ62_RS07005	COG1024	Enoyl-CoA hydratase
KXJ62_RS07020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KXJ62_RS07040	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KXJ62_RS07045	COG0148	phosphopyruvate hydratase activity
KXJ62_RS07055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KXJ62_RS07060	COG0508	dehydrogenase complex catalyzes the overall conversion of
KXJ62_RS07060	COG0022	dehydrogenase e1 component
KXJ62_RS07070	COG0508	dehydrogenase complex catalyzes the overall conversion of
KXJ62_RS07080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KXJ62_RS07090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KXJ62_RS07095	COG0697	spore germination
KXJ62_RS07115	COG2867	negative regulation of translational initiation
KXJ62_RS07125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KXJ62_RS07125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KXJ62_RS07135	COG3852	Histidine kinase
KXJ62_RS07140	COG2204	response regulator
KXJ62_RS07145	COG5000	phosphorelay sensor kinase activity
KXJ62_RS07150	COG2204	response regulator
KXJ62_RS07155	COG0569	domain protein
KXJ62_RS07160	COG1923	regulation of RNA biosynthetic process
KXJ62_RS07165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KXJ62_RS07170	COG3956	TIGRFAM MazG family protein
KXJ62_RS07180	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KXJ62_RS07180	COG1648	precorrin-2 dehydrogenase activity
KXJ62_RS07195	COG0275	rRNA processing
KXJ62_RS07220	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KXJ62_RS07220	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KXJ62_RS07225	COG0509	glycine decarboxylation via glycine cleavage system
KXJ62_RS07230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KXJ62_RS07255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KXJ62_RS07260	COG0564	pseudouridine synthase activity
KXJ62_RS07280	COG0251	oxidation-reduction process
KXJ62_RS07285	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KXJ62_RS07295	COG1671	Belongs to the UPF0178 family
KXJ62_RS07305	COG0450	alkyl hydroperoxide reductase
KXJ62_RS07345	COG2826	transposase and inactivated derivatives, IS30 family
KXJ62_RS07350	COG0431	NADPH-dependent FMN reductase
KXJ62_RS07360	COG0798	PFAM Bile acid sodium symporter
KXJ62_RS07380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KXJ62_RS07380	COG0321	lipoyl(octanoyl) transferase activity
KXJ62_RS07385	COG0084	hydrolase, TatD family'
KXJ62_RS07390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KXJ62_RS07400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KXJ62_RS07455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KXJ62_RS07460	COG2095	MarC family integral membrane protein
KXJ62_RS07465	COG0517	IMP dehydrogenase activity
KXJ62_RS07465	COG0617	tRNA 3'-terminal CCA addition
KXJ62_RS07465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KXJ62_RS07475	COG3609	addiction module antidote protein, CC2985 family
KXJ62_RS07480	COG0629	single-stranded DNA binding
KXJ62_RS07485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KXJ62_RS07495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KXJ62_RS07500	COG0179	Fumarylacetoacetate (FAA) hydrolase
KXJ62_RS07515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KXJ62_RS07520	COG1121	(ABC) transporter
KXJ62_RS07540	COG0667	Aldo Keto reductase
KXJ62_RS07550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KXJ62_RS07620	COG0668	transmembrane transport
KXJ62_RS07645	COG2239	Acts as a magnesium transporter
KXJ62_RS07650	COG0243	molybdopterin cofactor binding
KXJ62_RS07660	COG0242	peptide deformylase activity
KXJ62_RS07685	COG0321	lipoyl(octanoyl) transferase activity
KXJ62_RS07690	COG1064	alcohol dehydrogenase
KXJ62_RS07720	COG1862	Preprotein translocase
KXJ62_RS07745	COG2124	cytochrome p450
KXJ62_RS07760	COG0596	Alpha beta hydrolase
KXJ62_RS07775	COG0626	cystathionine gamma-synthase activity
KXJ62_RS07780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS07785	COG4597	amino acid ABC transporter
KXJ62_RS07790	COG0765	amino acid transport
KXJ62_RS07795	COG1126	abc transporter atp-binding protein
KXJ62_RS07810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KXJ62_RS07825	COG0436	Aminotransferase
KXJ62_RS07855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KXJ62_RS07865	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KXJ62_RS07870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KXJ62_RS07875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KXJ62_RS07890	COG3243	poly(R)-hydroxyalkanoic acid synthase
KXJ62_RS07895	COG1489	DNA binding
KXJ62_RS07900	COG0024	Methionine aminopeptidase
KXJ62_RS07905	COG2003	Belongs to the UPF0758 family
KXJ62_RS07920	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KXJ62_RS07935	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KXJ62_RS07940	COG0546	phosphoglycolate phosphatase activity
KXJ62_RS07950	COG0114	fumarate hydratase activity
KXJ62_RS07960	COG0504	CTP synthase activity
KXJ62_RS07970	COG0149	triose-phosphate isomerase activity
KXJ62_RS07980	COG0187	DNA topoisomerase II activity
KXJ62_RS07990	COG1309	transcriptional regulator
KXJ62_RS07995	COG2226	methyltransferase
KXJ62_RS08005	COG0740	serine-type endopeptidase activity
KXJ62_RS08015	COG0640	Transcriptional regulator
KXJ62_RS08020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KXJ62_RS08025	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS08035	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KXJ62_RS08035	COG3264	Mechanosensitive ion channel
KXJ62_RS08095	COG1127	ABC transporter
KXJ62_RS08100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KXJ62_RS08105	COG4948	Mandelate Racemase Muconate Lactonizing
KXJ62_RS08120	COG0280	phosphate acetyltransferase
KXJ62_RS08120	COG0281	malic enzyme
KXJ62_RS08130	COG0778	Nitroreductase
KXJ62_RS08135	COG0823	Involved in the tonB-independent uptake of proteins
KXJ62_RS08145	COG1368	sulfuric ester hydrolase activity
KXJ62_RS08170	COG0544	peptidyl-prolyl cis-trans isomerase activity
KXJ62_RS08190	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KXJ62_RS08195	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KXJ62_RS08235	COG0343	queuine tRNA-ribosyltransferase activity
KXJ62_RS08240	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KXJ62_RS08255	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KXJ62_RS08270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KXJ62_RS08275	COG0134	indole-3-glycerol-phosphate synthase activity
KXJ62_RS08280	COG0315	cyclic pyranopterin monophosphate synthase activity
KXJ62_RS08285	COG0303	'Molybdopterin
KXJ62_RS08290	COG3706	GGDEF domain
KXJ62_RS08300	COG0475	glutathione-regulated potassium exporter activity
KXJ62_RS08300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KXJ62_RS08310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KXJ62_RS08315	COG0697	spore germination
KXJ62_RS08320	COG2814	Major facilitator Superfamily
KXJ62_RS08325	COG0746	molybdenum cofactor guanylyltransferase activity
KXJ62_RS08330	COG1763	Mo-molybdopterin cofactor biosynthetic process
KXJ62_RS08335	COG0739	heme binding
KXJ62_RS08340	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KXJ62_RS08345	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KXJ62_RS08350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KXJ62_RS08355	COG0805	protein transport
KXJ62_RS08360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KXJ62_RS08365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KXJ62_RS08370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KXJ62_RS08375	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KXJ62_RS08380	COG1472	Belongs to the glycosyl hydrolase 3 family
KXJ62_RS08390	COG0018	arginyl-trna synthetase
KXJ62_RS08395	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KXJ62_RS08400	COG0316	Belongs to the HesB IscA family
KXJ62_RS08410	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KXJ62_RS08425	COG0525	valine-tRNA ligase activity
KXJ62_RS08435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KXJ62_RS08465	COG0655	NAD(P)H dehydrogenase (quinone) activity
KXJ62_RS08470	COG1058	Belongs to the CinA family
KXJ62_RS08470	COG1546	Belongs to the CinA family
KXJ62_RS08475	COG0589	response to stress
KXJ62_RS08480	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KXJ62_RS08485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KXJ62_RS08500	COG1914	H( )-stimulated, divalent metal cation uptake system
KXJ62_RS08510	COG1132	(ABC) transporter
KXJ62_RS08515	COG0628	permease
KXJ62_RS08535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KXJ62_RS08550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KXJ62_RS08560	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KXJ62_RS08570	COG0302	gtp cyclohydrolase
KXJ62_RS08575	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KXJ62_RS08580	COG1752	Esterase of the alpha-beta hydrolase superfamily
KXJ62_RS08585	COG0516	GMP reductase activity
KXJ62_RS08585	COG0517	IMP dehydrogenase activity
KXJ62_RS08615	COG1760	l-serine dehydratase
KXJ62_RS08650	COG0583	DNA-binding transcription factor activity
KXJ62_RS08660	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KXJ62_RS08660	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KXJ62_RS08665	COG0347	Belongs to the P(II) protein family
KXJ62_RS08670	COG0174	glutamine synthetase
KXJ62_RS08700	COG0697	spore germination
KXJ62_RS08710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KXJ62_RS08720	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KXJ62_RS08730	COG3668	Plasmid stabilization system
KXJ62_RS08735	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KXJ62_RS08750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KXJ62_RS08755	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KXJ62_RS08760	COG2186	Transcriptional regulator
KXJ62_RS08770	COG1079	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS08775	COG4603	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS08780	COG3845	ABC transporter
KXJ62_RS08785	COG1183	phosphatidylcholine synthase activity
KXJ62_RS08790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KXJ62_RS08795	COG0679	Auxin Efflux Carrier
KXJ62_RS08800	COG0785	Cytochrome C biogenesis protein
KXJ62_RS08830	COG1278	Cold shock
KXJ62_RS08880	COG2267	carboxylic ester hydrolase activity
KXJ62_RS08895	COG0577	efflux transmembrane transporter activity
KXJ62_RS08895	COG1136	(ABC) transporter
KXJ62_RS08900	COG1136	(ABC) transporter
KXJ62_RS08900	COG0577	efflux transmembrane transporter activity
KXJ62_RS08915	COG2151	metal-sulfur cluster biosynthetic enzyme
KXJ62_RS08920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KXJ62_RS08925	COG0719	Fe-S assembly protein
KXJ62_RS08930	COG0396	ATPase activity
KXJ62_RS08935	COG0719	Fe-S assembly protein
KXJ62_RS08940	COG1104	cysteine desulfurase activity
KXJ62_RS08945	COG2945	thiolester hydrolase activity
KXJ62_RS08950	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KXJ62_RS08955	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KXJ62_RS08965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KXJ62_RS08970	COG2833	Protein of unknown function (DUF455)
KXJ62_RS08975	COG0739	heme binding
KXJ62_RS08980	COG0513	Belongs to the DEAD box helicase family
KXJ62_RS09010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KXJ62_RS09020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KXJ62_RS09025	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KXJ62_RS09030	COG0047	phosphoribosylformylglycinamidine synthase activity
KXJ62_RS09045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KXJ62_RS09055	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KXJ62_RS09075	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KXJ62_RS09080	COG2814	Major facilitator Superfamily
KXJ62_RS09085	COG0483	inositol monophosphate 1-phosphatase activity
KXJ62_RS09090	COG0483	inositol monophosphate 1-phosphatase activity
KXJ62_RS09095	COG0037	tRNA processing
KXJ62_RS09100	COG2066	Belongs to the glutaminase family
KXJ62_RS09105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KXJ62_RS09110	COG0861	Integral membrane protein TerC family
KXJ62_RS09125	COG1280	lysine exporter protein (LysE YggA)
KXJ62_RS09135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KXJ62_RS09140	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KXJ62_RS09150	COG0538	isocitrate dehydrogenase activity
KXJ62_RS09165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KXJ62_RS09170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KXJ62_RS09175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ62_RS09180	COG2313	pseudouridylate synthase activity
KXJ62_RS09190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS09195	COG4215	(ABC) transporter
KXJ62_RS09205	COG5425	PFAM Usg family protein
KXJ62_RS09215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KXJ62_RS09220	COG1522	sequence-specific DNA binding
KXJ62_RS09225	COG1573	uracil-dna glycosylase
KXJ62_RS09235	COG2202	Pas domain
KXJ62_RS09235	COG2205	protein histidine kinase activity
KXJ62_RS09245	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KXJ62_RS09250	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KXJ62_RS09265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KXJ62_RS09270	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS09275	COG1129	ABC transporter
KXJ62_RS09285	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS09290	COG3959	Transketolase, thiamine diphosphate binding domain
KXJ62_RS09295	COG3958	Transketolase
KXJ62_RS09300	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KXJ62_RS09305	COG2390	Transcriptional regulator
KXJ62_RS09315	COG0842	Transport permease protein
KXJ62_RS09320	COG1131	(ABC) transporter
KXJ62_RS09345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KXJ62_RS09350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KXJ62_RS09365	COG0129	dihydroxy-acid dehydratase activity
KXJ62_RS09370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KXJ62_RS09375	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KXJ62_RS09385	COG3739	integral membrane protein
KXJ62_RS09390	COG0203	ribosomal protein L17
KXJ62_RS09395	COG0202	RNA polymerase activity
KXJ62_RS09400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KXJ62_RS09405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KXJ62_RS09410	COG0563	adenylate kinase activity
KXJ62_RS09415	COG0201	protein transport
KXJ62_RS09420	COG0200	Binds to the 23S rRNA
KXJ62_RS09425	COG1841	ribosomal large subunit assembly
KXJ62_RS09430	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KXJ62_RS09435	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KXJ62_RS09440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KXJ62_RS09445	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KXJ62_RS09450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KXJ62_RS09455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KXJ62_RS09460	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KXJ62_RS09465	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KXJ62_RS09470	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KXJ62_RS09475	COG0255	Belongs to the universal ribosomal protein uL29 family
KXJ62_RS09480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KXJ62_RS09485	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KXJ62_RS09490	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KXJ62_RS09495	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KXJ62_RS09500	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KXJ62_RS09505	COG0089	rRNA binding
KXJ62_RS09510	COG0088	Forms part of the polypeptide exit tunnel
KXJ62_RS09515	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KXJ62_RS09520	COG0051	transcription antitermination factor activity, RNA binding
KXJ62_RS09525	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KXJ62_RS09530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KXJ62_RS09535	COG0049	tRNA binding
KXJ62_RS09540	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KXJ62_RS09560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KXJ62_RS09565	COG0085	RNA polymerase activity
KXJ62_RS09570	COG0222	ribosome binding
KXJ62_RS09575	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KXJ62_RS09580	COG0081	regulation of translation
KXJ62_RS09585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KXJ62_RS09595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KXJ62_RS09605	COG1086	Polysaccharide biosynthesis protein
KXJ62_RS09610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KXJ62_RS09615	COG0861	Integral membrane protein TerC family
KXJ62_RS09620	COG3895	Periplasmic Protein
KXJ62_RS09640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KXJ62_RS09660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KXJ62_RS09695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS09695	COG2198	Histidine kinase
KXJ62_RS09695	COG2205	protein histidine kinase activity
KXJ62_RS09695	COG0784	Response regulator, receiver
KXJ62_RS09700	COG0784	Response regulator, receiver
KXJ62_RS09705	COG2202	Pas domain
KXJ62_RS09705	COG3920	Histidine kinase
KXJ62_RS09710	COG0784	Response regulator, receiver
KXJ62_RS09715	COG4251	negative regulation of phosphorylation
KXJ62_RS09730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KXJ62_RS09760	COG2910	NAD(P)H-binding
KXJ62_RS09765	COG1733	regulation of RNA biosynthetic process
KXJ62_RS09770	COG0556	nucleotide-excision repair
KXJ62_RS09775	COG2382	esterase
KXJ62_RS09795	COG0484	heat shock protein binding
KXJ62_RS09810	COG3706	GGDEF domain
KXJ62_RS09820	COG3842	ATPase activity
KXJ62_RS09830	COG1840	ABC-type Fe3 transport system, periplasmic component
KXJ62_RS09835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KXJ62_RS09845	COG4115	mRNA cleavage
KXJ62_RS09855	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KXJ62_RS09865	COG2207	Transcriptional regulator
KXJ62_RS09870	COG1064	alcohol dehydrogenase
KXJ62_RS09875	COG1252	NADH dehydrogenase
KXJ62_RS09880	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KXJ62_RS09885	COG2197	response regulator
KXJ62_RS09890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KXJ62_RS09920	COG0656	L-ascorbic acid biosynthetic process
KXJ62_RS09935	COG0440	acetolactate synthase activity
KXJ62_RS09940	COG0028	Belongs to the TPP enzyme family
KXJ62_RS09950	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KXJ62_RS09955	COG0560	Phosphoserine phosphatase
KXJ62_RS09955	COG3830	Belongs to the UPF0237 family
KXJ62_RS09965	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS09975	COG0330	HflC and HflK could
KXJ62_RS09980	COG0330	HflC and HflK could
KXJ62_RS09990	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KXJ62_RS10025	COG0277	FAD linked oxidase domain protein
KXJ62_RS10030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ62_RS10085	COG1335	isochorismatase
KXJ62_RS10105	COG0006	proline dipeptidase activity
KXJ62_RS10115	COG2264	protein methyltransferase activity
KXJ62_RS10120	COG1999	signal sequence binding
KXJ62_RS10130	COG0835	chemotaxis
KXJ62_RS10140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KXJ62_RS10145	COG0583	DNA-binding transcription factor activity
KXJ62_RS10155	COG1247	-acetyltransferase
KXJ62_RS10165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KXJ62_RS10170	COG0497	DNA recombination
KXJ62_RS10175	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KXJ62_RS10185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KXJ62_RS10190	COG0849	cell division
KXJ62_RS10195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KXJ62_RS10200	COG1181	Belongs to the D-alanine--D-alanine ligase family
KXJ62_RS10205	COG0477	Major facilitator Superfamily
KXJ62_RS10210	COG5001	Diguanylate cyclase
KXJ62_RS10210	COG3300	MHYT domain
KXJ62_RS10215	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KXJ62_RS10220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KXJ62_RS10225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KXJ62_RS10235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KXJ62_RS10240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KXJ62_RS10250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KXJ62_RS10265	COG0275	rRNA processing
KXJ62_RS10270	COG2001	Belongs to the MraZ family
KXJ62_RS10275	COG3766	membrane
KXJ62_RS10320	COG3023	N-Acetylmuramoyl-L-alanine amidase
KXJ62_RS10350	COG4106	trans-aconitate 2-methyltransferase activity
KXJ62_RS10370	COG2226	methyltransferase
KXJ62_RS10380	COG2267	carboxylic ester hydrolase activity
KXJ62_RS10385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KXJ62_RS10400	COG0251	oxidation-reduction process
KXJ62_RS10415	COG1376	ErfK ybiS ycfS ynhG family protein
KXJ62_RS10420	COG2814	Major facilitator Superfamily
KXJ62_RS10445	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS10460	COG0174	glutamine synthetase
KXJ62_RS10465	COG0531	amino acid
KXJ62_RS10475	COG1737	Transcriptional regulator
KXJ62_RS10495	COG3842	ATPase activity
KXJ62_RS10555	COG2968	Membrane
KXJ62_RS10565	COG0432	Pfam Uncharacterised protein family UPF0047
KXJ62_RS10580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KXJ62_RS10585	COG0358	DNA primase activity
KXJ62_RS10595	COG0505	Belongs to the CarA family
KXJ62_RS10610	COG0534	Mate efflux family protein
KXJ62_RS10625	COG2321	neutral zinc metallopeptidase
KXJ62_RS10640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KXJ62_RS10650	COG3706	GGDEF domain
KXJ62_RS10665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KXJ62_RS10675	COG1522	sequence-specific DNA binding
KXJ62_RS10680	COG0492	ferredoxin-NADP+ reductase activity
KXJ62_RS10685	COG0583	DNA-binding transcription factor activity
KXJ62_RS10695	COG1902	pentaerythritol trinitrate reductase activity
KXJ62_RS10720	COG0387	Pfam Sodium calcium exchanger
KXJ62_RS10725	COG0436	Aminotransferase
KXJ62_RS10730	COG2199	diguanylate cyclase activity
KXJ62_RS10730	COG2200	EAL domain
KXJ62_RS10745	COG1278	Cold shock
KXJ62_RS10750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KXJ62_RS10760	COG1846	Transcriptional regulator
KXJ62_RS10765	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS10770	COG2205	protein histidine kinase activity
KXJ62_RS10775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KXJ62_RS10795	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KXJ62_RS10805	COG1496	oxidoreductase activity
KXJ62_RS10820	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KXJ62_RS10830	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KXJ62_RS10845	COG0840	transmembrane signaling receptor activity
KXJ62_RS10850	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS10855	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KXJ62_RS10860	COG5001	Diguanylate cyclase
KXJ62_RS10860	COG3300	MHYT domain
KXJ62_RS10865	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KXJ62_RS10870	COG5001	Diguanylate cyclase
KXJ62_RS10880	COG0193	aminoacyl-tRNA hydrolase activity
KXJ62_RS10890	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KXJ62_RS10910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KXJ62_RS10915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KXJ62_RS10915	COG2857	Cytochrome c1
KXJ62_RS10935	COG1132	(ABC) transporter
KXJ62_RS10940	COG1132	(ABC) transporter
KXJ62_RS10945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KXJ62_RS10950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KXJ62_RS10965	COG0408	coproporphyrinogen oxidase activity
KXJ62_RS10980	COG0617	tRNA 3'-terminal CCA addition
KXJ62_RS10985	COG0494	nUDIX hydrolase
KXJ62_RS10995	COG0714	Associated with various cellular activities
KXJ62_RS11015	COG0454	-acetyltransferase
KXJ62_RS11020	COG0477	Major facilitator Superfamily
KXJ62_RS11030	COG0435	Glutathione S-transferase
KXJ62_RS11035	COG0494	nUDIX hydrolase
KXJ62_RS11045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KXJ62_RS11050	COG3135	benzoate transporter
KXJ62_RS11065	COG1595	DNA-templated transcription, initiation
KXJ62_RS11075	COG0740	serine-type endopeptidase activity
KXJ62_RS11090	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KXJ62_RS11095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KXJ62_RS11120	COG4175	Glycine betaine
KXJ62_RS11135	COG1435	thymidine kinase activity
KXJ62_RS11155	COG2862	Uncharacterized protein family, UPF0114
KXJ62_RS11170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KXJ62_RS11170	COG0512	Glutamine amidotransferase of anthranilate synthase
KXJ62_RS11185	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KXJ62_RS11200	COG0366	Alpha amylase catalytic
KXJ62_RS11205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ62_RS11225	COG1160	GTP binding
KXJ62_RS11245	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KXJ62_RS11255	COG0024	Methionine aminopeptidase
KXJ62_RS11265	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS11275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KXJ62_RS11285	COG0583	DNA-binding transcription factor activity
KXJ62_RS11300	COG0402	S-adenosylhomocysteine deaminase activity
KXJ62_RS11315	COG1304	FMN binding
KXJ62_RS11325	COG1309	transcriptional regulator
KXJ62_RS11330	COG1686	Belongs to the peptidase S11 family
KXJ62_RS11340	COG2351	hydroxyisourate hydrolase activity
KXJ62_RS11345	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KXJ62_RS11370	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KXJ62_RS11380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS11380	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KXJ62_RS11390	COG0513	Belongs to the DEAD box helicase family
KXJ62_RS11395	COG0697	spore germination
KXJ62_RS11400	COG2259	Doxx family
KXJ62_RS11405	COG1376	ErfK ybiS ycfS ynhG family protein
KXJ62_RS11415	COG2308	Evidence 4 Homologs of previously reported genes of
KXJ62_RS11425	COG1305	Transglutaminase-like
KXJ62_RS11430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KXJ62_RS11440	COG0456	acetyltransferase
KXJ62_RS11455	COG4214	carbohydrate transport
KXJ62_RS11460	COG1129	ABC transporter
KXJ62_RS11465	COG4213	ABC transporter substrate-binding protein
KXJ62_RS11500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KXJ62_RS11510	COG0840	transmembrane signaling receptor activity
KXJ62_RS11515	COG2814	Major facilitator Superfamily
KXJ62_RS11520	COG0646	methionine synthase
KXJ62_RS11520	COG1410	methionine synthase
KXJ62_RS11530	COG4215	(ABC) transporter
KXJ62_RS11535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS11560	COG1215	transferase activity, transferring glycosyl groups
KXJ62_RS11590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KXJ62_RS11595	COG2346	COG2346, Truncated hemoglobins
KXJ62_RS11615	COG1309	transcriptional regulator
KXJ62_RS11630	COG0494	nUDIX hydrolase
KXJ62_RS11640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ62_RS11645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ62_RS11675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KXJ62_RS11680	COG0830	nickel cation binding
KXJ62_RS11685	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KXJ62_RS11700	COG0804	urea catabolic process
KXJ62_RS11705	COG1442	glycosyl transferase family 8
KXJ62_RS11710	COG3755	Protein conserved in bacteria
KXJ62_RS11720	COG0832	Belongs to the urease beta subunit family
KXJ62_RS11725	COG3813	Protein conserved in bacteria
KXJ62_RS11730	COG0831	urea catabolic process
KXJ62_RS11735	COG0829	nickel cation binding
KXJ62_RS11760	COG0559	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS11775	COG0174	glutamine synthetase
KXJ62_RS11780	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS11785	COG0784	Response regulator, receiver
KXJ62_RS11785	COG2198	Histidine kinase
KXJ62_RS11785	COG5002	protein histidine kinase activity
KXJ62_RS11835	COG1218	3'(2'),5'-bisphosphate nucleotidase
KXJ62_RS11910	COG0564	pseudouridine synthase activity
KXJ62_RS11920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KXJ62_RS11930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KXJ62_RS11955	COG0346	lactoylglutathione lyase activity
KXJ62_RS11965	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KXJ62_RS11975	COG2832	Protein of unknown function (DUF454)
KXJ62_RS11980	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KXJ62_RS11985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KXJ62_RS11990	COG4558	Periplasmic binding protein
KXJ62_RS12000	COG3721	Heme iron utilization protein
KXJ62_RS12015	COG2205	protein histidine kinase activity
KXJ62_RS12055	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KXJ62_RS12060	COG4605	iron ion homeostasis
KXJ62_RS12065	COG4604	ABC transporter, ATP-binding protein
KXJ62_RS12070	COG0783	Belongs to the Dps family
KXJ62_RS12085	COG0583	DNA-binding transcription factor activity
KXJ62_RS12090	COG0657	acetylesterase activity
KXJ62_RS12095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ62_RS12115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KXJ62_RS12120	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KXJ62_RS12125	COG0288	reversible hydration of carbon dioxide
KXJ62_RS12135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KXJ62_RS12150	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KXJ62_RS12155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KXJ62_RS12160	COG0778	Nitroreductase
KXJ62_RS12165	COG2267	carboxylic ester hydrolase activity
KXJ62_RS12170	COG0251	oxidation-reduction process
KXJ62_RS12175	COG1335	isochorismatase
KXJ62_RS12180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS12190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ62_RS12205	COG1175	transmembrane transport
KXJ62_RS12210	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS12215	COG3842	ATPase activity
KXJ62_RS12220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ62_RS12230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KXJ62_RS12245	COG4608	Belongs to the ABC transporter superfamily
KXJ62_RS12250	COG0444	Belongs to the ABC transporter superfamily
KXJ62_RS12255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS12260	COG0601	transmembrane transport
KXJ62_RS12280	COG0392	lysyltransferase activity
KXJ62_RS12280	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KXJ62_RS12325	COG1960	acyl-CoA dehydrogenase activity
KXJ62_RS12355	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS12365	COG1902	pentaerythritol trinitrate reductase activity
KXJ62_RS12365	COG0446	pyridine nucleotide-disulphide oxidoreductase
KXJ62_RS12400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KXJ62_RS12410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ62_RS12415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ62_RS12425	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KXJ62_RS12435	COG1509	lysine 2,3-aminomutase activity
KXJ62_RS12450	COG0583	DNA-binding transcription factor activity
KXJ62_RS12455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS12460	COG0725	ABC transporter, periplasmic molybdate-binding protein
KXJ62_RS12465	COG4149	molybdate abc transporter
KXJ62_RS12470	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KXJ62_RS12480	COG3191	aminopeptidase activity
KXJ62_RS12485	COG2022	thiamine diphosphate biosynthetic process
KXJ62_RS12500	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KXJ62_RS12505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KXJ62_RS12515	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KXJ62_RS12540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KXJ62_RS12565	COG0438	transferase activity, transferring glycosyl groups
KXJ62_RS12585	COG4166	transmembrane transport
KXJ62_RS12595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS12605	COG0438	transferase activity, transferring glycosyl groups
KXJ62_RS12610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KXJ62_RS12615	COG3142	Participates in the control of copper homeostasis
KXJ62_RS12635	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS12640	COG1737	Transcriptional regulator
KXJ62_RS12650	COG3842	ATPase activity
KXJ62_RS12660	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS12665	COG1175	transmembrane transport
KXJ62_RS12675	COG2188	Transcriptional regulator
KXJ62_RS12680	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KXJ62_RS12685	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KXJ62_RS12690	COG1940	carbohydrate kinase activity
KXJ62_RS12700	COG0671	phosphoesterase, PA-phosphatase related
KXJ62_RS12705	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KXJ62_RS12710	COG0156	8-amino-7-oxononanoate synthase activity
KXJ62_RS12720	COG0729	surface antigen
KXJ62_RS12730	COG0835	chemotaxis
KXJ62_RS12740	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KXJ62_RS12745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KXJ62_RS12750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KXJ62_RS12755	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KXJ62_RS12760	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KXJ62_RS12765	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KXJ62_RS12780	COG4974	Belongs to the 'phage' integrase family
KXJ62_RS12805	COG1280	lysine exporter protein (LysE YggA)
KXJ62_RS12815	COG0508	dehydrogenase complex catalyzes the overall conversion of
KXJ62_RS12825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KXJ62_RS12830	COG0045	succinate-CoA ligase (ADP-forming) activity
KXJ62_RS12835	COG0039	L-malate dehydrogenase activity
KXJ62_RS12840	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KXJ62_RS12875	COG2264	protein methyltransferase activity
KXJ62_RS12890	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KXJ62_RS12895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KXJ62_RS12900	COG0181	hydroxymethylbilane synthase activity
KXJ62_RS12940	COG1872	DUF167
KXJ62_RS12945	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KXJ62_RS12955	COG1217	gtp-binding protein TYPA
KXJ62_RS12960	COG0339	signal peptide processing
KXJ62_RS12965	COG1846	Transcriptional regulator
KXJ62_RS12975	COG0137	argininosuccinate synthase activity
KXJ62_RS12985	COG1280	lysine exporter protein (LysE YggA)
KXJ62_RS12990	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KXJ62_RS12995	COG4120	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS13005	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KXJ62_RS13020	COG2154	pterin-4-alpha-carbinolamine dehydratase
KXJ62_RS13025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KXJ62_RS13030	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KXJ62_RS13040	COG4181	ATPase activity
KXJ62_RS13050	COG0670	Belongs to the BI1 family
KXJ62_RS13065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KXJ62_RS13070	COG4133	protoheme IX ABC transporter activity
KXJ62_RS13075	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KXJ62_RS13080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KXJ62_RS13105	COG2917	probably involved in intracellular septation
KXJ62_RS13110	COG0552	protein localization to endoplasmic reticulum
KXJ62_RS13115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KXJ62_RS13120	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KXJ62_RS13130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KXJ62_RS13135	COG0287	Prephenate dehydrogenase
KXJ62_RS13135	COG1605	Chorismate mutase
KXJ62_RS13140	COG0228	four-way junction DNA binding
KXJ62_RS13145	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KXJ62_RS13150	COG0336	Belongs to the RNA methyltransferase TrmD family
KXJ62_RS13160	COG0335	large ribosomal subunit rRNA binding
KXJ62_RS13165	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
KXJ62_RS13170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ62_RS13185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KXJ62_RS13195	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KXJ62_RS13215	COG0488	(ABC) transporter
KXJ62_RS13225	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KXJ62_RS13235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KXJ62_RS13240	COG0142	geranyltranstransferase activity
KXJ62_RS13245	COG2885	chlorophyll binding
KXJ62_RS13250	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KXJ62_RS13255	COG2223	nitrite transmembrane transporter activity
KXJ62_RS13260	COG1349	DNA-binding transcription factor activity
KXJ62_RS13265	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KXJ62_RS13270	COG2197	response regulator
KXJ62_RS13275	COG1132	(ABC) transporter
KXJ62_RS13285	COG3459	Glycosyltransferase 36 associated
KXJ62_RS13290	COG1473	amidohydrolase
KXJ62_RS13295	COG0579	oxidoreductase
KXJ62_RS13305	COG0129	dihydroxy-acid dehydratase activity
KXJ62_RS13310	COG2084	Dehydrogenase
KXJ62_RS13315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KXJ62_RS13320	COG0277	FAD linked oxidase domain protein
KXJ62_RS13325	COG2186	Transcriptional regulator
KXJ62_RS13335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KXJ62_RS13340	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KXJ62_RS13345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KXJ62_RS13350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KXJ62_RS13360	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KXJ62_RS13365	COG0495	leucyl-tRNA aminoacylation
KXJ62_RS13380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KXJ62_RS13395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KXJ62_RS13400	COG1946	Acyl-CoA thioesterase
KXJ62_RS13405	COG0347	Belongs to the P(II) protein family
KXJ62_RS13410	COG0004	ammonium transporteR
KXJ62_RS13415	COG1674	ftsk spoiiie
KXJ62_RS13420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KXJ62_RS13435	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS13445	COG1329	Transcriptional regulator
KXJ62_RS13450	COG2902	Dehydrogenase
KXJ62_RS13455	COG2270	Major facilitator Superfamily
KXJ62_RS13470	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS13485	COG0494	nUDIX hydrolase
KXJ62_RS13495	COG0793	Belongs to the peptidase S41A family
KXJ62_RS13505	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KXJ62_RS13510	COG0799	negative regulation of ribosome biogenesis
KXJ62_RS13515	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KXJ62_RS13520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KXJ62_RS13525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KXJ62_RS13530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KXJ62_RS13545	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KXJ62_RS13550	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KXJ62_RS13575	COG0066	3-isopropylmalate dehydratase activity
KXJ62_RS13580	COG0473	3-isopropylmalate dehydrogenase activity
KXJ62_RS13585	COG1858	cytochrome C peroxidase
KXJ62_RS13590	COG1797	cobyrinic acid a,c-diamide synthase activity
KXJ62_RS13595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KXJ62_RS13595	COG1648	precorrin-2 dehydrogenase activity
KXJ62_RS13600	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KXJ62_RS13665	COG1492	cobalamin metabolic process
KXJ62_RS13680	COG4948	Mandelate Racemase Muconate Lactonizing
KXJ62_RS13685	COG3254	rhamnose metabolic process
KXJ62_RS13690	COG0246	Mannitol dehydrogenase
KXJ62_RS13695	COG1063	alcohol dehydrogenase
KXJ62_RS13715	COG4214	carbohydrate transport
KXJ62_RS13720	COG1129	ABC transporter
KXJ62_RS13725	COG2186	Transcriptional regulator
KXJ62_RS13730	COG2721	sulfolactate sulfo-lyase activity
KXJ62_RS13735	COG0138	bifunctional purine biosynthesis protein purh
KXJ62_RS13745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KXJ62_RS13745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KXJ62_RS13750	COG0501	Belongs to the peptidase M48B family
KXJ62_RS13770	COG0357	Ribosomal RNA small subunit methyltransferase G
KXJ62_RS13775	COG0445	tRNA wobble uridine modification
KXJ62_RS13780	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KXJ62_RS13785	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KXJ62_RS13790	COG1981	membrane
KXJ62_RS13795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KXJ62_RS13825	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KXJ62_RS13835	COG0640	Transcriptional regulator
KXJ62_RS13880	COG3842	ATPase activity
KXJ62_RS13885	COG4209	transmembrane transport
KXJ62_RS13890	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS13895	COG1653	transport
KXJ62_RS13905	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS13915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KXJ62_RS13925	COG4948	Mandelate Racemase Muconate Lactonizing
KXJ62_RS13950	COG1846	Transcriptional regulator
KXJ62_RS13950	COG1940	carbohydrate kinase activity
KXJ62_RS13955	COG2197	response regulator
KXJ62_RS13960	COG0601	transmembrane transport
KXJ62_RS13965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS13985	COG0747	negative chemotaxis
KXJ62_RS14000	COG1446	asparaginase
KXJ62_RS14010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS14015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS14020	COG0601	transmembrane transport
KXJ62_RS14060	COG1215	transferase activity, transferring glycosyl groups
KXJ62_RS14070	COG0025	NhaP-type Na H and K H
KXJ62_RS14075	COG4178	(ABC) transporter
KXJ62_RS14085	COG1609	Transcriptional regulator
KXJ62_RS14100	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS14105	COG1735	metal-dependent hydrolase with the TIM-barrel fold
KXJ62_RS14140	COG1794	racemase activity, acting on amino acids and derivatives
KXJ62_RS14145	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS14150	COG1309	transcriptional regulator
KXJ62_RS14155	COG2233	PERMEase
KXJ62_RS14195	COG1595	DNA-templated transcription, initiation
KXJ62_RS14205	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS14210	COG1176	ABC-type spermidine putrescine transport system, permease component I
KXJ62_RS14220	COG3842	ATPase activity
KXJ62_RS14255	COG1653	transport
KXJ62_RS14265	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS14270	COG3842	ATPase activity
KXJ62_RS14275	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS14280	COG1175	transmembrane transport
KXJ62_RS14310	COG1609	Transcriptional regulator
KXJ62_RS14320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KXJ62_RS14325	COG1082	Xylose isomerase domain protein TIM barrel
KXJ62_RS14330	COG3842	ATPase activity
KXJ62_RS14335	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS14340	COG1175	transmembrane transport
KXJ62_RS14345	COG1653	transport
KXJ62_RS14350	COG1309	transcriptional regulator
KXJ62_RS14355	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS14370	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS14380	COG1278	Cold shock
KXJ62_RS14390	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KXJ62_RS14415	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KXJ62_RS14430	COG3842	ATPase activity
KXJ62_RS14435	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS14440	COG1175	transmembrane transport
KXJ62_RS14460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KXJ62_RS14465	COG3618	amidohydrolase
KXJ62_RS14470	COG4948	Mandelate Racemase Muconate Lactonizing
KXJ62_RS14475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ62_RS14480	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS14485	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KXJ62_RS14490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KXJ62_RS14495	COG2186	Transcriptional regulator
KXJ62_RS14545	COG2223	nitrite transmembrane transporter activity
KXJ62_RS14550	COG0583	DNA-binding transcription factor activity
KXJ62_RS14555	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KXJ62_RS14565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KXJ62_RS14570	COG2084	Dehydrogenase
KXJ62_RS14585	COG1609	Transcriptional regulator
KXJ62_RS14590	COG1063	alcohol dehydrogenase
KXJ62_RS14595	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS14605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ62_RS14610	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
KXJ62_RS14615	COG1175	transmembrane transport
KXJ62_RS14620	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS14635	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS14640	COG1175	transmembrane transport
KXJ62_RS14645	COG2182	Extracellular solute-binding protein
KXJ62_RS14650	COG0626	cystathionine gamma-synthase activity
KXJ62_RS14665	COG0803	Belongs to the bacterial solute-binding protein 9 family
KXJ62_RS14675	COG1121	(ABC) transporter
KXJ62_RS14680	COG0523	cobalamin synthesis protein
KXJ62_RS14695	COG0523	cobalamin synthesis protein
KXJ62_RS14700	COG1653	transport
KXJ62_RS14705	COG1175	transmembrane transport
KXJ62_RS14710	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS14715	COG3842	ATPase activity
KXJ62_RS14730	COG3047	cAMP biosynthetic process
KXJ62_RS14755	COG0583	DNA-binding transcription factor activity
KXJ62_RS14760	COG1879	ABC-type sugar transport system periplasmic component
KXJ62_RS14765	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS14770	COG1129	ABC transporter
KXJ62_RS14780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ62_RS14785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ62_RS14790	COG5001	Diguanylate cyclase
KXJ62_RS14790	COG3447	MASE1 domain protein
KXJ62_RS14790	COG5002	protein histidine kinase activity
KXJ62_RS14795	COG3257	ureidoglycine aminohydrolase activity
KXJ62_RS14805	COG5001	Diguanylate cyclase
KXJ62_RS14810	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KXJ62_RS14825	COG0747	negative chemotaxis
KXJ62_RS14830	COG0601	transmembrane transport
KXJ62_RS14835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS14845	COG4608	Belongs to the ABC transporter superfamily
KXJ62_RS14850	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KXJ62_RS14860	COG0129	dihydroxy-acid dehydratase activity
KXJ62_RS14870	COG1879	ABC-type sugar transport system periplasmic component
KXJ62_RS14875	COG1129	ABC transporter
KXJ62_RS14880	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS14885	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS14890	COG2186	Transcriptional regulator
KXJ62_RS14900	COG0587	DNA-directed DNA polymerase activity
KXJ62_RS14930	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS14940	COG3842	ATPase activity
KXJ62_RS14945	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS14950	COG1175	transmembrane transport
KXJ62_RS14955	COG1653	transport
KXJ62_RS14965	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS14980	COG5001	Diguanylate cyclase
KXJ62_RS14985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS14995	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KXJ62_RS15000	COG2894	cell division
KXJ62_RS15005	COG0850	regulation of cytokinetic process
KXJ62_RS15010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KXJ62_RS15015	COG2186	Transcriptional regulator
KXJ62_RS15020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KXJ62_RS15030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KXJ62_RS15035	COG1063	alcohol dehydrogenase
KXJ62_RS15040	COG1312	Catalyzes the dehydration of D-mannonate
KXJ62_RS15055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KXJ62_RS15060	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KXJ62_RS15065	COG4172	Belongs to the ABC transporter superfamily
KXJ62_RS15070	COG1921	L-seryl-tRNASec selenium transferase activity
KXJ62_RS15085	COG3964	amidohydrolase
KXJ62_RS15095	COG0601	transmembrane transport
KXJ62_RS15100	COG0747	negative chemotaxis
KXJ62_RS15105	COG0438	transferase activity, transferring glycosyl groups
KXJ62_RS15130	COG2911	Protein conserved in bacteria
KXJ62_RS15130	COG3210	domain, Protein
KXJ62_RS15140	COG4989	oxidoreductase activity
KXJ62_RS15155	COG3842	ATPase activity
KXJ62_RS15160	COG1653	transport
KXJ62_RS15165	COG1175	transmembrane transport
KXJ62_RS15170	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS15175	COG1501	Belongs to the glycosyl hydrolase 31 family
KXJ62_RS15180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ62_RS15185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KXJ62_RS15190	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KXJ62_RS15195	COG0352	thiamine-phosphate diphosphorylase activity
KXJ62_RS15200	COG0351	phosphomethylpyrimidine kinase
KXJ62_RS15205	COG1522	sequence-specific DNA binding
KXJ62_RS15210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KXJ62_RS15215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS15230	COG2204	response regulator
KXJ62_RS15235	COG4191	Histidine kinase
KXJ62_RS15240	COG1301	dicarboxylic acid transport
KXJ62_RS15250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KXJ62_RS15255	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS15265	COG1473	amidohydrolase
KXJ62_RS15285	COG1215	transferase activity, transferring glycosyl groups
KXJ62_RS15295	COG2942	2-epimerase
KXJ62_RS15330	COG2197	response regulator
KXJ62_RS15360	COG3307	-O-antigen
KXJ62_RS15365	COG1596	polysaccharide export
KXJ62_RS15370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KXJ62_RS15380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KXJ62_RS15385	COG0840	transmembrane signaling receptor activity
KXJ62_RS15385	COG2972	Histidine kinase
KXJ62_RS15390	COG1376	ErfK ybiS ycfS ynhG family protein
KXJ62_RS15390	COG1388	LysM domain
KXJ62_RS15400	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS15410	COG2094	Belongs to the DNA glycosylase MPG family
KXJ62_RS15425	COG1609	Transcriptional regulator
KXJ62_RS15430	COG1653	transport
KXJ62_RS15445	COG3842	ATPase activity
KXJ62_RS15455	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS15460	COG0602	queuosine metabolic process
KXJ62_RS15465	COG0720	synthase
KXJ62_RS15470	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KXJ62_RS15475	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS15490	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS15495	COG1175	transmembrane transport
KXJ62_RS15515	COG0583	DNA-binding transcription factor activity
KXJ62_RS15520	COG0281	malic enzyme
KXJ62_RS15520	COG0280	phosphate acetyltransferase
KXJ62_RS15535	COG0765	amino acid transport
KXJ62_RS15540	COG1126	abc transporter atp-binding protein
KXJ62_RS15545	COG2079	MmgE PrpD family protein
KXJ62_RS15550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS15575	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KXJ62_RS15580	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KXJ62_RS15585	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KXJ62_RS15590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KXJ62_RS15595	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS15600	COG1129	ABC transporter
KXJ62_RS15610	COG1473	amidohydrolase
KXJ62_RS15630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS15635	COG0601	transmembrane transport
KXJ62_RS15640	COG0583	DNA-binding transcription factor activity
KXJ62_RS15645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ62_RS15650	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
KXJ62_RS15670	COG1595	DNA-templated transcription, initiation
KXJ62_RS15675	COG1120	ATPase activity
KXJ62_RS15680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KXJ62_RS15695	COG2226	methyltransferase
KXJ62_RS15705	COG1120	ATPase activity
KXJ62_RS15710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KXJ62_RS15730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KXJ62_RS15740	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS15745	COG0473	3-isopropylmalate dehydrogenase activity
KXJ62_RS15750	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS15755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS15785	COG0601	transmembrane transport
KXJ62_RS15790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS15795	COG4172	Belongs to the ABC transporter superfamily
KXJ62_RS15800	COG1522	sequence-specific DNA binding
KXJ62_RS15805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS15815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS15820	COG1126	abc transporter atp-binding protein
KXJ62_RS15835	COG1473	amidohydrolase
KXJ62_RS15840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS15845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS15850	COG1959	2 iron, 2 sulfur cluster binding
KXJ62_RS15860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KXJ62_RS15865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS15880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS15885	COG1960	acyl-CoA dehydrogenase activity
KXJ62_RS15920	COG0667	Aldo Keto reductase
KXJ62_RS15930	COG0583	DNA-binding transcription factor activity
KXJ62_RS15935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS15955	COG1473	amidohydrolase
KXJ62_RS15960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS15975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS15980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS16000	COG4608	Belongs to the ABC transporter superfamily
KXJ62_RS16005	COG0444	Belongs to the ABC transporter superfamily
KXJ62_RS16015	COG0601	transmembrane transport
KXJ62_RS16025	COG2186	Transcriptional regulator
KXJ62_RS16050	COG3453	Protein conserved in bacteria
KXJ62_RS16050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KXJ62_RS16055	COG0640	Transcriptional regulator
KXJ62_RS16065	COG2391	methyltransferase activity
KXJ62_RS16070	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KXJ62_RS16080	COG0022	dehydrogenase e1 component
KXJ62_RS16090	COG1960	acyl-CoA dehydrogenase activity
KXJ62_RS16095	COG0183	Belongs to the thiolase family
KXJ62_RS16105	COG1960	acyl-CoA dehydrogenase activity
KXJ62_RS16110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KXJ62_RS16125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KXJ62_RS16130	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KXJ62_RS16135	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KXJ62_RS16140	COG4952	isomerase
KXJ62_RS16145	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS16145	COG3347	Dehydrogenase
KXJ62_RS16150	COG1349	DNA-binding transcription factor activity
KXJ62_RS16160	COG1129	ABC transporter
KXJ62_RS16165	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS16175	COG3254	rhamnose metabolic process
KXJ62_RS16190	COG2264	protein methyltransferase activity
KXJ62_RS16195	COG5001	Diguanylate cyclase
KXJ62_RS16215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KXJ62_RS16220	COG4208	sulfate ABC transporter
KXJ62_RS16230	COG4150	thiosulfate binding
KXJ62_RS16250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KXJ62_RS16260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KXJ62_RS16270	COG1040	competence protein
KXJ62_RS16275	COG2226	methyltransferase
KXJ62_RS16290	COG0494	nUDIX hydrolase
KXJ62_RS16300	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KXJ62_RS16305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KXJ62_RS16310	COG0653	protein targeting
KXJ62_RS16315	COG0697	spore germination
KXJ62_RS16355	COG1312	Catalyzes the dehydration of D-mannonate
KXJ62_RS16360	COG0246	Mannitol dehydrogenase
KXJ62_RS16380	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS16385	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS16390	COG1129	ABC transporter
KXJ62_RS16420	COG2376	Dihydroxyacetone kinase
KXJ62_RS16425	COG3273	potassium ion transport
KXJ62_RS16425	COG0471	metal ion transport
KXJ62_RS16445	COG0438	transferase activity, transferring glycosyl groups
KXJ62_RS16455	COG2244	polysaccharide biosynthetic process
KXJ62_RS16480	COG0489	protein tyrosine kinase activity
KXJ62_RS16480	COG3206	protein involved in exopolysaccharide biosynthesis
KXJ62_RS16500	COG0438	transferase activity, transferring glycosyl groups
KXJ62_RS16505	COG0438	transferase activity, transferring glycosyl groups
KXJ62_RS16520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KXJ62_RS16525	COG2273	Hydrolase Family 16
KXJ62_RS16525	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
KXJ62_RS16570	COG1396	sequence-specific DNA binding
KXJ62_RS16580	COG1129	ABC transporter
KXJ62_RS16585	COG4214	carbohydrate transport
KXJ62_RS16590	COG4213	ABC transporter substrate-binding protein
KXJ62_RS16605	COG0346	lactoylglutathione lyase activity
KXJ62_RS16610	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KXJ62_RS16610	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KXJ62_RS16615	COG4770	biotin carboxylase activity
KXJ62_RS16625	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KXJ62_RS16635	COG0625	glutathione transferase activity
KXJ62_RS16640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KXJ62_RS16645	COG1396	sequence-specific DNA binding
KXJ62_RS16645	COG3800	Transcriptional regulator
KXJ62_RS16655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KXJ62_RS16665	COG0300	oxidoreductase activity
KXJ62_RS16675	COG2096	Adenosyltransferase
KXJ62_RS16685	COG2086	electron transfer activity
KXJ62_RS16695	COG1250	3-hydroxyacyl-CoA dehydrogenase
KXJ62_RS16700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KXJ62_RS16705	COG0165	Argininosuccinate lyase
KXJ62_RS16740	COG2884	Cell division ATP-binding protein ftsE
KXJ62_RS16760	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KXJ62_RS16770	COG0287	Prephenate dehydrogenase
KXJ62_RS16775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KXJ62_RS16780	COG2226	methyltransferase
KXJ62_RS16785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KXJ62_RS16800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KXJ62_RS16805	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KXJ62_RS16840	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KXJ62_RS16845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KXJ62_RS16855	COG4974	Belongs to the 'phage' integrase family
KXJ62_RS16860	COG0825	malonyl-CoA metabolic process
KXJ62_RS16865	COG3034	peptidoglycan biosynthetic process
KXJ62_RS16870	COG0425	Belongs to the sulfur carrier protein TusA family
KXJ62_RS16870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KXJ62_RS16875	COG0523	cobalamin synthesis protein
KXJ62_RS16880	COG1686	Belongs to the peptidase S11 family
KXJ62_RS16885	COG1473	amidohydrolase
KXJ62_RS16895	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KXJ62_RS16965	COG0456	acetyltransferase
KXJ62_RS17000	COG2267	carboxylic ester hydrolase activity
KXJ62_RS17010	COG1959	2 iron, 2 sulfur cluster binding
KXJ62_RS17015	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KXJ62_RS17055	COG2226	methyltransferase
KXJ62_RS17090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KXJ62_RS17110	COG4774	siderophore transport
KXJ62_RS17110	COG1629	transport
KXJ62_RS17115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KXJ62_RS17120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KXJ62_RS17125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KXJ62_RS17130	COG1120	ATPase activity
KXJ62_RS17145	COG4953	penicillin-binding protein 1C
KXJ62_RS17150	COG2373	Large extracellular alpha-helical protein
KXJ62_RS17155	COG2835	tetraacyldisaccharide 4'-kinase activity
KXJ62_RS17165	COG3118	belongs to the thioredoxin family
KXJ62_RS17180	COG0625	glutathione transferase activity
KXJ62_RS17190	COG0482	sulfurtransferase activity
KXJ62_RS17205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KXJ62_RS17220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KXJ62_RS17225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KXJ62_RS17230	COG0037	tRNA processing
KXJ62_RS17240	COG2885	chlorophyll binding
KXJ62_RS17245	COG0823	Involved in the tonB-independent uptake of proteins
KXJ62_RS17265	COG0824	Thioesterase
KXJ62_RS17270	COG0494	nUDIX hydrolase
KXJ62_RS17285	COG2255	four-way junction helicase activity
KXJ62_RS17290	COG0632	four-way junction helicase activity
KXJ62_RS17295	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KXJ62_RS17300	COG0840	transmembrane signaling receptor activity
KXJ62_RS17305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS17310	COG0217	transcriptional regulatory protein
KXJ62_RS17325	COG1692	metallophosphoesterase
KXJ62_RS17335	COG1253	flavin adenine dinucleotide binding
KXJ62_RS17365	COG3263	regulation of cellular component size
KXJ62_RS17370	COG0126	phosphoglycerate kinase activity
KXJ62_RS17375	COG3588	fructose-bisphosphate aldolase
KXJ62_RS17400	COG0254	rRNA binding
KXJ62_RS17405	COG1132	(ABC) transporter
KXJ62_RS17425	COG0483	inositol monophosphate 1-phosphatase activity
KXJ62_RS17455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KXJ62_RS17460	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KXJ62_RS17465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KXJ62_RS17470	COG0457	Tetratricopeptide repeat
KXJ62_RS17475	COG3750	Belongs to the UPF0335 family
KXJ62_RS17495	COG0469	pyruvate kinase activity
KXJ62_RS17500	COG3108	Peptidase M15
KXJ62_RS17505	COG2204	response regulator
KXJ62_RS17510	COG1164	Oligoendopeptidase f
KXJ62_RS17515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KXJ62_RS17525	COG5310	Homospermidine synthase
KXJ62_RS17535	COG0737	Belongs to the 5'-nucleotidase family
KXJ62_RS17540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KXJ62_RS17545	COG0330	HflC and HflK could
KXJ62_RS17570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KXJ62_RS17575	COG2951	lytic endotransglycosylase activity
KXJ62_RS17590	COG2205	protein histidine kinase activity
KXJ62_RS17605	COG0067	glutamate synthase
KXJ62_RS17605	COG0069	glutamate synthase activity
KXJ62_RS17605	COG0070	glutamate synthase
KXJ62_RS17615	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS17620	COG2205	protein histidine kinase activity
KXJ62_RS17625	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KXJ62_RS17630	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KXJ62_RS17640	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KXJ62_RS17650	COG0252	asparaginase activity
KXJ62_RS17660	COG1027	Aspartate ammonia-lyase
KXJ62_RS17665	COG2186	Transcriptional regulator
KXJ62_RS17705	COG4176	ABC-type proline glycine betaine transport system permease component
KXJ62_RS17710	COG0517	IMP dehydrogenase activity
KXJ62_RS17710	COG4175	Glycine betaine
KXJ62_RS17715	COG2986	histidine ammonia-lyase
KXJ62_RS17720	COG2814	Major facilitator Superfamily
KXJ62_RS17735	COG1522	sequence-specific DNA binding
KXJ62_RS17740	COG0583	DNA-binding transcription factor activity
KXJ62_RS17745	COG0667	Aldo Keto reductase
KXJ62_RS17755	COG1335	isochorismatase
KXJ62_RS17765	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS17770	COG3254	rhamnose metabolic process
KXJ62_RS17785	COG2721	sulfolactate sulfo-lyase activity
KXJ62_RS17790	COG1129	ABC transporter
KXJ62_RS17800	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS17805	COG1879	ABC-type sugar transport system periplasmic component
KXJ62_RS17840	COG0583	DNA-binding transcription factor activity
KXJ62_RS17990	COG2307	Protein conserved in bacteria
KXJ62_RS17990	COG2308	Evidence 4 Homologs of previously reported genes of
KXJ62_RS18005	COG0488	(ABC) transporter
KXJ62_RS18010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KXJ62_RS18015	COG1304	FMN binding
KXJ62_RS18025	COG1846	Transcriptional regulator
KXJ62_RS18035	COG1070	Carbohydrate kinase
KXJ62_RS18045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KXJ62_RS18050	COG0667	Aldo Keto reductase
KXJ62_RS18060	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS18065	COG1129	ABC transporter
KXJ62_RS18070	COG1879	ABC-type sugar transport system periplasmic component
KXJ62_RS18105	COG0071	Belongs to the small heat shock protein (HSP20) family
KXJ62_RS18120	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KXJ62_RS18135	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS18150	COG3842	ATPase activity
KXJ62_RS18165	COG1648	precorrin-2 dehydrogenase activity
KXJ62_RS18165	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KXJ62_RS18170	COG0243	molybdopterin cofactor binding
KXJ62_RS18180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KXJ62_RS18185	COG1116	anion transmembrane transporter activity
KXJ62_RS18190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ62_RS18195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KXJ62_RS18205	COG3707	response regulator
KXJ62_RS18210	COG1802	Transcriptional regulator
KXJ62_RS18215	COG1914	H( )-stimulated, divalent metal cation uptake system
KXJ62_RS18220	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KXJ62_RS18225	COG4336	lyase activity
KXJ62_RS18230	COG1984	allophanate hydrolase subunit 2
KXJ62_RS18235	COG4770	biotin carboxylase activity
KXJ62_RS18240	COG0366	Alpha amylase catalytic
KXJ62_RS18250	COG4771	TonB-dependent receptor
KXJ62_RS18275	COG1414	Transcriptional regulator
KXJ62_RS18280	COG1475	DNA binding
KXJ62_RS18285	COG1192	Involved in chromosome partitioning
KXJ62_RS18320	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KXJ62_RS18330	COG2986	histidine ammonia-lyase
KXJ62_RS18335	COG1228	amidohydrolase
KXJ62_RS18340	COG0402	S-adenosylhomocysteine deaminase activity
KXJ62_RS18385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS18395	COG2423	ornithine cyclodeaminase activity
KXJ62_RS18410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS18415	COG3938	Belongs to the proline racemase family
KXJ62_RS18420	COG4176	ABC-type proline glycine betaine transport system permease component
KXJ62_RS18430	COG3448	diguanylate cyclase activity
KXJ62_RS18430	COG4175	Glycine betaine
KXJ62_RS18440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS18445	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS18450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ62_RS18480	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS18485	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS18495	COG1175	transmembrane transport
KXJ62_RS18500	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS18505	COG3842	ATPase activity
KXJ62_RS18515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KXJ62_RS18520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KXJ62_RS18545	COG0583	DNA-binding transcription factor activity
KXJ62_RS18550	COG0346	lactoylglutathione lyase activity
KXJ62_RS18565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KXJ62_RS18575	COG2814	Major facilitator Superfamily
KXJ62_RS18590	COG0583	DNA-binding transcription factor activity
KXJ62_RS18595	COG0477	Major facilitator Superfamily
KXJ62_RS18645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KXJ62_RS18655	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KXJ62_RS18660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KXJ62_RS18665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KXJ62_RS18695	COG0010	Belongs to the arginase family
KXJ62_RS18715	COG0697	spore germination
KXJ62_RS18720	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS18740	COG0477	Major facilitator Superfamily
KXJ62_RS18745	COG0642	Histidine kinase
KXJ62_RS18755	COG2194	sulfuric ester hydrolase activity
KXJ62_RS18760	COG0583	DNA-binding transcription factor activity
KXJ62_RS18765	COG4774	siderophore transport
KXJ62_RS18780	COG1120	ATPase activity
KXJ62_RS18790	COG3474	cytochrome
KXJ62_RS18795	COG2137	regulation of response to DNA damage stimulus
KXJ62_RS18800	COG3386	PFAM SMP-30 Gluconolaconase
KXJ62_RS18810	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS18815	COG1129	ABC transporter
KXJ62_RS18820	COG1879	ABC-type sugar transport system periplasmic component
KXJ62_RS18825	COG4585	Histidine kinase
KXJ62_RS18830	COG2197	response regulator
KXJ62_RS18840	COG2133	pyrroloquinoline quinone binding
KXJ62_RS18850	COG0500	methyltransferase
KXJ62_RS18855	COG0564	pseudouridine synthase activity
KXJ62_RS18870	COG4175	Glycine betaine
KXJ62_RS18870	COG0517	IMP dehydrogenase activity
KXJ62_RS18875	COG4176	ABC-type proline glycine betaine transport system permease component
KXJ62_RS18885	COG4191	Histidine kinase
KXJ62_RS18885	COG0784	Response regulator, receiver
KXJ62_RS18890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KXJ62_RS18895	COG0489	protein tyrosine kinase activity
KXJ62_RS18895	COG3206	protein involved in exopolysaccharide biosynthesis
KXJ62_RS18900	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KXJ62_RS18905	COG1215	transferase activity, transferring glycosyl groups
KXJ62_RS18910	COG1215	transferase activity, transferring glycosyl groups
KXJ62_RS18915	COG1215	transferase activity, transferring glycosyl groups
KXJ62_RS18920	COG0438	transferase activity, transferring glycosyl groups
KXJ62_RS18925	COG2273	Hydrolase Family 16
KXJ62_RS18930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KXJ62_RS18935	COG2244	polysaccharide biosynthetic process
KXJ62_RS18940	COG0463	Glycosyl transferase, family 2
KXJ62_RS18945	COG2327	Polysaccharide pyruvyl transferase
KXJ62_RS18950	COG1215	transferase activity, transferring glycosyl groups
KXJ62_RS18970	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KXJ62_RS18975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS18990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KXJ62_RS18990	COG0446	pyridine nucleotide-disulphide oxidoreductase
KXJ62_RS19015	COG0033	Phosphoglucomutase
KXJ62_RS19020	COG0297	glycogen (starch) synthase activity
KXJ62_RS19025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KXJ62_RS19030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KXJ62_RS19035	COG0058	SHG alpha-glucan phosphorylase activity
KXJ62_RS19045	COG1794	racemase activity, acting on amino acids and derivatives
KXJ62_RS19050	COG1522	sequence-specific DNA binding
KXJ62_RS19060	COG2084	Dehydrogenase
KXJ62_RS19065	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS19070	COG1063	alcohol dehydrogenase
KXJ62_RS19080	COG4988	ABC transporter
KXJ62_RS19085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KXJ62_RS19095	COG1294	oxidase, subunit
KXJ62_RS19125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KXJ62_RS19130	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KXJ62_RS19160	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KXJ62_RS19165	COG0539	negative regulation of cytoplasmic translation
KXJ62_RS19195	COG4221	oxidoreductase activity
KXJ62_RS19200	COG0006	proline dipeptidase activity
KXJ62_RS19205	COG0747	negative chemotaxis
KXJ62_RS19210	COG0601	transmembrane transport
KXJ62_RS19215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS19220	COG0444	Belongs to the ABC transporter superfamily
KXJ62_RS19240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS19265	COG0559	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS19285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KXJ62_RS19290	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS19310	COG4993	Dehydrogenase
KXJ62_RS19315	COG3685	Protein conserved in bacteria
KXJ62_RS19345	COG0693	protein deglycase activity
KXJ62_RS19365	COG0189	ligase activity
KXJ62_RS19370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KXJ62_RS19375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KXJ62_RS19385	COG0583	DNA-binding transcription factor activity
KXJ62_RS19390	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS19395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KXJ62_RS19400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ62_RS19405	COG1116	anion transmembrane transporter activity
KXJ62_RS19415	COG1522	sequence-specific DNA binding
KXJ62_RS19430	COG0784	Response regulator, receiver
KXJ62_RS19440	COG3920	Histidine kinase
KXJ62_RS19450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KXJ62_RS19465	COG0019	diaminopimelate decarboxylase activity
KXJ62_RS19475	COG0513	Belongs to the DEAD box helicase family
KXJ62_RS19480	COG0527	aspartate kinase activity
KXJ62_RS19490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KXJ62_RS19495	COG2890	protein-(glutamine-N5) methyltransferase activity
KXJ62_RS19505	COG0542	response to heat
KXJ62_RS19510	COG0741	lytic transglycosylase activity
KXJ62_RS19510	COG1196	nuclear chromosome segregation
KXJ62_RS19510	COG0739	heme binding
KXJ62_RS19550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ62_RS19560	COG2186	Transcriptional regulator
KXJ62_RS19565	COG0747	negative chemotaxis
KXJ62_RS19570	COG0601	transmembrane transport
KXJ62_RS19575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS19580	COG4172	Belongs to the ABC transporter superfamily
KXJ62_RS19585	COG4948	Mandelate Racemase Muconate Lactonizing
KXJ62_RS19620	COG1881	PFAM PEBP family protein
KXJ62_RS19660	COG3833	ABC-type maltose transport systems, permease component
KXJ62_RS19670	COG0584	glycerophosphoryl diester phosphodiesterase
KXJ62_RS19675	COG1278	Cold shock
KXJ62_RS19690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KXJ62_RS19710	COG0300	oxidoreductase activity
KXJ62_RS19720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KXJ62_RS19720	COG0446	pyridine nucleotide-disulphide oxidoreductase
KXJ62_RS19725	COG4311	Sarcosine oxidase, delta subunit
KXJ62_RS19730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS19735	COG4977	sequence-specific DNA binding
KXJ62_RS19745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KXJ62_RS19750	COG2218	PFAM glutamate synthase alpha subunit domain protein
KXJ62_RS19755	COG0069	glutamate synthase activity
KXJ62_RS19760	COG0174	glutamine synthetase
KXJ62_RS19780	COG0765	amino acid transport
KXJ62_RS19785	COG1126	abc transporter atp-binding protein
KXJ62_RS19790	COG1454	alcohol dehydrogenase
KXJ62_RS19800	COG2267	carboxylic ester hydrolase activity
KXJ62_RS19810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS19815	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS19835	COG1177	transmembrane transport
KXJ62_RS19840	COG3842	ATPase activity
KXJ62_RS19855	COG3842	ATPase activity
KXJ62_RS19860	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS19865	COG1175	transmembrane transport
KXJ62_RS19875	COG1053	succinate dehydrogenase
KXJ62_RS19875	COG3976	FMN-binding domain protein
KXJ62_RS19880	COG1609	Transcriptional regulator
KXJ62_RS19890	COG4172	Belongs to the ABC transporter superfamily
KXJ62_RS19895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS19900	COG0601	transmembrane transport
KXJ62_RS19910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ62_RS19925	COG2828	Protein conserved in bacteria
KXJ62_RS19930	COG0583	DNA-binding transcription factor activity
KXJ62_RS19940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KXJ62_RS19960	COG0494	nUDIX hydrolase
KXJ62_RS19965	COG0583	DNA-binding transcription factor activity
KXJ62_RS19975	COG0511	ligase activity, forming carbon-carbon bonds
KXJ62_RS19980	COG0439	Biotin carboxylase
KXJ62_RS19995	COG1984	allophanate hydrolase subunit 2
KXJ62_RS20000	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KXJ62_RS20005	COG0436	Aminotransferase
KXJ62_RS20015	COG4221	oxidoreductase activity
KXJ62_RS20020	COG0765	amino acid transport
KXJ62_RS20025	COG0765	amino acid transport
KXJ62_RS20030	COG1126	abc transporter atp-binding protein
KXJ62_RS20035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS20040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KXJ62_RS20055	COG0583	DNA-binding transcription factor activity
KXJ62_RS20065	COG0583	DNA-binding transcription factor activity
KXJ62_RS20070	COG2814	Major facilitator Superfamily
KXJ62_RS20085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KXJ62_RS20095	COG2207	Transcriptional regulator
KXJ62_RS20100	COG0668	transmembrane transport
KXJ62_RS20110	COG4566	intracellular signal transduction
KXJ62_RS20130	COG0668	transmembrane transport
KXJ62_RS20135	COG4191	Histidine kinase
KXJ62_RS20140	COG0784	Response regulator, receiver
KXJ62_RS20140	COG2205	protein histidine kinase activity
KXJ62_RS20140	COG5002	protein histidine kinase activity
KXJ62_RS20145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KXJ62_RS20160	COG0047	phosphoribosylformylglycinamidine synthase activity
KXJ62_RS20175	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KXJ62_RS20175	COG0446	pyridine nucleotide-disulphide oxidoreductase
KXJ62_RS20185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KXJ62_RS20200	COG1309	transcriptional regulator
KXJ62_RS20205	COG1063	alcohol dehydrogenase
KXJ62_RS20215	COG1879	ABC-type sugar transport system periplasmic component
KXJ62_RS20225	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS20375	COG5001	Diguanylate cyclase
KXJ62_RS20385	COG1253	flavin adenine dinucleotide binding
KXJ62_RS20400	COG3842	ATPase activity
KXJ62_RS20405	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS20410	COG1175	transmembrane transport
KXJ62_RS20415	COG1653	transport
KXJ62_RS20425	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS20430	COG1609	Transcriptional regulator
KXJ62_RS20445	COG0583	DNA-binding transcription factor activity
KXJ62_RS20455	COG1879	ABC-type sugar transport system periplasmic component
KXJ62_RS20460	COG1129	ABC transporter
KXJ62_RS20465	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS20470	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS20475	COG1609	Transcriptional regulator
KXJ62_RS20485	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS20545	COG0714	Associated with various cellular activities
KXJ62_RS20550	COG3256	nitric oxide reductase
KXJ62_RS20580	COG0163	prenyltransferase activity
KXJ62_RS20585	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KXJ62_RS20590	COG3189	MarR family transcriptional regulator
KXJ62_RS20600	COG0826	peptidase U32
KXJ62_RS20640	COG4459	periplasmic nitrate reductase
KXJ62_RS20655	COG0243	molybdopterin cofactor binding
KXJ62_RS20665	COG3005	denitrification pathway
KXJ62_RS20670	COG0583	DNA-binding transcription factor activity
KXJ62_RS20685	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
KXJ62_RS20690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ62_RS20705	COG1960	acyl-CoA dehydrogenase activity
KXJ62_RS20710	COG0583	DNA-binding transcription factor activity
KXJ62_RS20715	COG1609	Transcriptional regulator
KXJ62_RS20725	COG1176	ABC-type spermidine putrescine transport system, permease component I
KXJ62_RS20735	COG3842	ATPase activity
KXJ62_RS20745	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KXJ62_RS20755	COG1473	amidohydrolase
KXJ62_RS20770	COG0747	negative chemotaxis
KXJ62_RS20775	COG0601	transmembrane transport
KXJ62_RS20780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS20785	COG0444	Belongs to the ABC transporter superfamily
KXJ62_RS20790	COG4608	Belongs to the ABC transporter superfamily
KXJ62_RS20800	COG0583	DNA-binding transcription factor activity
KXJ62_RS20805	COG0747	negative chemotaxis
KXJ62_RS20815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS20820	COG0154	amidase activity
KXJ62_RS20825	COG0693	protein deglycase activity
KXJ62_RS20835	COG1473	amidohydrolase
KXJ62_RS20840	COG4172	Belongs to the ABC transporter superfamily
KXJ62_RS20845	COG2390	Transcriptional regulator
KXJ62_RS20855	COG1175	transmembrane transport
KXJ62_RS20860	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS20875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KXJ62_RS20880	COG1069	ribulokinase activity
KXJ62_RS20885	COG1737	Transcriptional regulator
KXJ62_RS20905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KXJ62_RS20925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KXJ62_RS20930	COG1414	Transcriptional regulator
KXJ62_RS20935	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS20945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KXJ62_RS20950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KXJ62_RS20955	COG1121	(ABC) transporter
KXJ62_RS20960	COG0803	Belongs to the bacterial solute-binding protein 9 family
KXJ62_RS20970	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KXJ62_RS20975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KXJ62_RS20980	COG3273	potassium ion transport
KXJ62_RS20980	COG0471	metal ion transport
KXJ62_RS20985	COG1253	flavin adenine dinucleotide binding
KXJ62_RS20990	COG1309	transcriptional regulator
KXJ62_RS21010	COG1609	Transcriptional regulator
KXJ62_RS21015	COG1070	Carbohydrate kinase
KXJ62_RS21020	COG2115	Belongs to the xylose isomerase family
KXJ62_RS21030	COG0778	Nitroreductase
KXJ62_RS21035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KXJ62_RS21040	COG2011	ABC-type metal ion transport system permease component
KXJ62_RS21050	COG5001	Diguanylate cyclase
KXJ62_RS21050	COG3300	MHYT domain
KXJ62_RS21055	COG1054	Belongs to the UPF0176 family
KXJ62_RS21065	COG2954	triphosphatase activity
KXJ62_RS21070	COG0800	Aldolase
KXJ62_RS21090	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
KXJ62_RS21110	COG0523	cobalamin synthesis protein
KXJ62_RS21120	COG1846	Transcriptional regulator
KXJ62_RS21125	COG1609	Transcriptional regulator
KXJ62_RS21130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KXJ62_RS21135	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS21140	COG3718	enzyme involved in inositol metabolism
KXJ62_RS21150	COG3962	Belongs to the TPP enzyme family
KXJ62_RS21155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ62_RS21170	COG0411	ABC transporter
KXJ62_RS21185	COG0683	leucine binding
KXJ62_RS21205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS21215	COG0747	negative chemotaxis
KXJ62_RS21230	COG1082	Xylose isomerase domain protein TIM barrel
KXJ62_RS21230	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KXJ62_RS21240	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KXJ62_RS21245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KXJ62_RS21250	COG1126	abc transporter atp-binding protein
KXJ62_RS21255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS21260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS21265	COG0765	amino acid transport
KXJ62_RS21270	COG0765	amino acid transport
KXJ62_RS21280	COG3485	protocatechuate 3,4-dioxygenase
KXJ62_RS21285	COG3485	protocatechuate 3,4-dioxygenase
KXJ62_RS21290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KXJ62_RS21300	COG0583	DNA-binding transcription factor activity
KXJ62_RS21315	COG1414	Transcriptional regulator
KXJ62_RS21325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KXJ62_RS21330	COG0183	Belongs to the thiolase family
KXJ62_RS21335	COG1609	Transcriptional regulator
KXJ62_RS21350	COG1082	Xylose isomerase domain protein TIM barrel
KXJ62_RS21355	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS21365	COG1609	Transcriptional regulator
KXJ62_RS21370	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS21375	COG1175	transmembrane transport
KXJ62_RS21380	COG3842	ATPase activity
KXJ62_RS21390	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KXJ62_RS21415	COG1940	carbohydrate kinase activity
KXJ62_RS21425	COG3842	ATPase activity
KXJ62_RS21430	COG4149	molybdate abc transporter
KXJ62_RS21440	COG0584	glycerophosphoryl diester phosphodiesterase
KXJ62_RS21445	COG0483	inositol monophosphate 1-phosphatase activity
KXJ62_RS21450	COG0300	oxidoreductase activity
KXJ62_RS21470	COG3842	ATPase activity
KXJ62_RS21490	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KXJ62_RS21525	COG0667	Aldo Keto reductase
KXJ62_RS21530	COG0583	DNA-binding transcription factor activity
KXJ62_RS21540	COG0179	Fumarylacetoacetate (FAA) hydrolase
KXJ62_RS21550	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS21560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ62_RS21575	COG1132	(ABC) transporter
KXJ62_RS21615	COG1215	transferase activity, transferring glycosyl groups
KXJ62_RS21630	COG1215	transferase activity, transferring glycosyl groups
KXJ62_RS21640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KXJ62_RS21645	COG1091	dTDP-4-dehydrorhamnose reductase activity
KXJ62_RS21650	COG1088	dTDP-glucose 4,6-dehydratase activity
KXJ62_RS21655	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KXJ62_RS21670	COG0444	Belongs to the ABC transporter superfamily
KXJ62_RS21675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS21680	COG0601	transmembrane transport
KXJ62_RS21685	COG2186	Transcriptional regulator
KXJ62_RS21690	COG1312	Catalyzes the dehydration of D-mannonate
KXJ62_RS21695	COG0747	negative chemotaxis
KXJ62_RS21705	COG5001	Diguanylate cyclase
KXJ62_RS21705	COG3300	MHYT domain
KXJ62_RS21710	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS21720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KXJ62_RS21735	COG1392	Phosphate transport regulator
KXJ62_RS21760	COG5002	protein histidine kinase activity
KXJ62_RS21775	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KXJ62_RS21790	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS21805	COG3119	arylsulfatase activity
KXJ62_RS21810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ62_RS21815	COG3842	ATPase activity
KXJ62_RS21820	COG0165	Argininosuccinate lyase
KXJ62_RS21825	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS21830	COG1175	transmembrane transport
KXJ62_RS21835	COG2182	Extracellular solute-binding protein
KXJ62_RS21840	COG1940	carbohydrate kinase activity
KXJ62_RS21865	COG1486	melibiose metabolic process
KXJ62_RS21870	COG0747	negative chemotaxis
KXJ62_RS21875	COG0601	transmembrane transport
KXJ62_RS21880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS21885	COG4172	Belongs to the ABC transporter superfamily
KXJ62_RS21890	COG1486	melibiose metabolic process
KXJ62_RS21895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ62_RS21900	COG0842	Transport permease protein
KXJ62_RS21900	COG1129	ABC transporter
KXJ62_RS21905	COG0842	Transport permease protein
KXJ62_RS21920	COG0784	Response regulator, receiver
KXJ62_RS21925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KXJ62_RS21935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ62_RS21940	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KXJ62_RS21955	COG0765	amino acid transport
KXJ62_RS21965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ62_RS21975	COG3938	Belongs to the proline racemase family
KXJ62_RS21990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS21995	COG0765	amino acid transport
KXJ62_RS22000	COG0765	amino acid transport
KXJ62_RS22010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KXJ62_RS22025	COG0402	S-adenosylhomocysteine deaminase activity
KXJ62_RS22035	COG0601	transmembrane transport
KXJ62_RS22040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS22050	COG0402	S-adenosylhomocysteine deaminase activity
KXJ62_RS22055	COG0444	Belongs to the ABC transporter superfamily
KXJ62_RS22060	COG4608	Belongs to the ABC transporter superfamily
KXJ62_RS22065	COG1802	Transcriptional regulator
KXJ62_RS22070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KXJ62_RS22095	COG3383	formate dehydrogenase (NAD+) activity
KXJ62_RS22105	COG2223	nitrite transmembrane transporter activity
KXJ62_RS22135	COG3237	CsbD-like
KXJ62_RS22140	COG2197	response regulator
KXJ62_RS22145	COG2186	Transcriptional regulator
KXJ62_RS22150	COG0747	negative chemotaxis
KXJ62_RS22155	COG0601	transmembrane transport
KXJ62_RS22160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS22165	COG0405	Gamma-glutamyltransferase
KXJ62_RS22175	COG3237	CsbD-like
KXJ62_RS22185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KXJ62_RS22190	COG3181	Tripartite tricarboxylate transporter family receptor
KXJ62_RS22195	COG5265	(ABC) transporter
KXJ62_RS22200	COG0488	(ABC) transporter
KXJ62_RS22225	COG1049	propionate catabolic process, 2-methylcitrate cycle
KXJ62_RS22230	COG0840	transmembrane signaling receptor activity
KXJ62_RS22240	COG0110	maltose O-acetyltransferase activity
KXJ62_RS22250	COG1063	alcohol dehydrogenase
KXJ62_RS22255	COG3284	Transcriptional regulator
KXJ62_RS22275	COG1129	ABC transporter
KXJ62_RS22280	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS22285	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS22300	COG1082	Xylose isomerase domain protein TIM barrel
KXJ62_RS22310	COG1126	abc transporter atp-binding protein
KXJ62_RS22315	COG0765	amino acid transport
KXJ62_RS22320	COG0765	amino acid transport
KXJ62_RS22325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS22330	COG3608	succinylglutamate desuccinylase aspartoacylase
KXJ62_RS22335	COG0006	proline dipeptidase activity
KXJ62_RS22340	COG2423	ornithine cyclodeaminase activity
KXJ62_RS22345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KXJ62_RS22350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KXJ62_RS22355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KXJ62_RS22360	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS22365	COG1522	sequence-specific DNA binding
KXJ62_RS22375	COG3046	protein related to deoxyribodipyrimidine photolyase
KXJ62_RS22405	COG2140	Oxalate decarboxylase
KXJ62_RS22420	COG4566	intracellular signal transduction
KXJ62_RS22430	COG0243	molybdopterin cofactor binding
KXJ62_RS22435	COG0783	Belongs to the Dps family
KXJ62_RS22455	COG4191	Histidine kinase
KXJ62_RS22455	COG0784	Response regulator, receiver
KXJ62_RS22465	COG1840	ABC-type Fe3 transport system, periplasmic component
KXJ62_RS22470	COG1840	ABC-type Fe3 transport system, periplasmic component
KXJ62_RS22480	COG3842	ATPase activity
KXJ62_RS22485	COG0483	inositol monophosphate 1-phosphatase activity
KXJ62_RS22500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KXJ62_RS22530	COG2197	response regulator
KXJ62_RS22535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KXJ62_RS22540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KXJ62_RS22550	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KXJ62_RS22555	COG4310	Domain of unknown function (DUF2172)
KXJ62_RS22560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KXJ62_RS22565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KXJ62_RS22570	COG2197	response regulator
KXJ62_RS22575	COG4566	intracellular signal transduction
KXJ62_RS22605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KXJ62_RS22625	COG0438	transferase activity, transferring glycosyl groups
KXJ62_RS22640	COG1522	sequence-specific DNA binding
KXJ62_RS22660	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS22675	COG1414	Transcriptional regulator
KXJ62_RS22685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KXJ62_RS22705	COG0582	viral genome integration into host DNA
KXJ62_RS22725	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KXJ62_RS22755	COG1349	DNA-binding transcription factor activity
KXJ62_RS22760	COG1879	ABC-type sugar transport system periplasmic component
KXJ62_RS22765	COG1129	ABC transporter
KXJ62_RS22770	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS22775	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS22795	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS22870	COG1846	Transcriptional regulator
KXJ62_RS22890	COG0667	Aldo Keto reductase
KXJ62_RS22895	COG0604	alcohol dehydrogenase
KXJ62_RS22905	COG1309	transcriptional regulator
KXJ62_RS22920	COG0667	Aldo Keto reductase
KXJ62_RS22925	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS22940	COG0662	Cupin 2, conserved barrel domain protein
KXJ62_RS22940	COG2207	Transcriptional regulator
KXJ62_RS23020	COG1192	Involved in chromosome partitioning
KXJ62_RS23025	COG1475	DNA binding
KXJ62_RS23030	COG0640	Transcriptional regulator
KXJ62_RS23045	COG1126	abc transporter atp-binding protein
KXJ62_RS23055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS23060	COG1609	Transcriptional regulator
KXJ62_RS23145	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KXJ62_RS23150	COG0210	DNA helicase
KXJ62_RS23215	COG3177	Filamentation induced by cAMP protein fic
KXJ62_RS23290	COG0071	Belongs to the small heat shock protein (HSP20) family
KXJ62_RS23325	COG1175	transmembrane transport
KXJ62_RS23330	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS23340	COG3842	ATPase activity
KXJ62_RS23345	COG1737	Transcriptional regulator
KXJ62_RS23350	COG1846	Transcriptional regulator
KXJ62_RS23365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ62_RS23375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS23380	COG0601	transmembrane transport
KXJ62_RS23385	COG0747	negative chemotaxis
KXJ62_RS23395	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KXJ62_RS23400	COG1454	alcohol dehydrogenase
KXJ62_RS23410	COG3395	kinase activity
KXJ62_RS23425	COG1609	Transcriptional regulator
KXJ62_RS23465	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KXJ62_RS23470	COG3920	Histidine kinase
KXJ62_RS23485	COG1215	transferase activity, transferring glycosyl groups
KXJ62_RS23530	COG0587	DNA-directed DNA polymerase activity
KXJ62_RS23550	COG5489	Protein of unknown function (DUF736)
KXJ62_RS23560	COG0776	regulation of translation
KXJ62_RS23565	COG3831	ATPase activity
KXJ62_RS23570	COG3505	Type IV secretory pathway VirD4
KXJ62_RS23620	COG0156	8-amino-7-oxononanoate synthase activity
KXJ62_RS23625	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS23635	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS23640	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS23645	COG0028	Belongs to the TPP enzyme family
KXJ62_RS23650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KXJ62_RS23660	COG3842	ATPase activity
KXJ62_RS23665	COG1176	ABC-type spermidine putrescine transport system, permease component I
KXJ62_RS23670	COG1177	transmembrane transport
KXJ62_RS23695	COG1414	Transcriptional regulator
KXJ62_RS23705	COG1454	alcohol dehydrogenase
KXJ62_RS23710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KXJ62_RS23740	COG1285	pathogenesis
KXJ62_RS23760	COG1733	regulation of RNA biosynthetic process
KXJ62_RS23805	COG3838	Conjugal transfer protein Trbc
KXJ62_RS23810	COG3702	type iv secretory pathway
KXJ62_RS23815	COG3451	type IV secretory pathway VirB4
KXJ62_RS23830	COG3704	protein secretion by the type IV secretion system
KXJ62_RS23840	COG3736	Type IV secretory pathway, component VirB8
KXJ62_RS23845	COG3504	Conjugal transfer protein
KXJ62_RS23850	COG2948	multi-organism process
KXJ62_RS23855	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
KXJ62_RS23870	COG0745	RESPONSE REGULATOR receiver
KXJ62_RS23880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ62_RS23885	COG1136	(ABC) transporter
KXJ62_RS23885	COG0577	efflux transmembrane transporter activity
KXJ62_RS23895	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS23900	COG1063	alcohol dehydrogenase
KXJ62_RS23910	COG0583	DNA-binding transcription factor activity
KXJ62_RS23915	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS23920	COG0583	DNA-binding transcription factor activity
KXJ62_RS23935	COG2267	carboxylic ester hydrolase activity
KXJ62_RS23940	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS23950	COG0789	Transcriptional regulator
KXJ62_RS23960	COG1376	ErfK ybiS ycfS ynhG family protein
KXJ62_RS23970	COG0667	Aldo Keto reductase
KXJ62_RS23975	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS24000	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS24010	COG0583	DNA-binding transcription factor activity
KXJ62_RS24020	COG0583	DNA-binding transcription factor activity
KXJ62_RS24030	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS24035	COG1846	Transcriptional regulator
KXJ62_RS24050	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS24065	COG4176	ABC-type proline glycine betaine transport system permease component
KXJ62_RS24070	COG2113	Glycine betaine
KXJ62_RS24075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KXJ62_RS24100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ62_RS24105	COG1012	belongs to the aldehyde dehydrogenase family
KXJ62_RS24135	COG0765	amino acid transport
KXJ62_RS24150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS24155	COG3608	succinylglutamate desuccinylase aspartoacylase
KXJ62_RS24160	COG1609	Transcriptional regulator
KXJ62_RS24170	COG0583	DNA-binding transcription factor activity
KXJ62_RS24185	COG1335	isochorismatase
KXJ62_RS24190	COG1177	transmembrane transport
KXJ62_RS24195	COG1176	ABC-type spermidine putrescine transport system, permease component I
KXJ62_RS24200	COG3842	ATPase activity
KXJ62_RS24225	COG0747	negative chemotaxis
KXJ62_RS24230	COG0601	transmembrane transport
KXJ62_RS24235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS24240	COG0444	Belongs to the ABC transporter superfamily
KXJ62_RS24245	COG4608	Belongs to the ABC transporter superfamily
KXJ62_RS24265	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KXJ62_RS24270	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS24295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KXJ62_RS24300	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KXJ62_RS24315	COG2378	regulation of single-species biofilm formation
KXJ62_RS24325	COG1846	Transcriptional regulator
KXJ62_RS24340	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS24350	COG3685	Protein conserved in bacteria
KXJ62_RS24380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KXJ62_RS24385	COG0297	glycogen (starch) synthase activity
KXJ62_RS24405	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KXJ62_RS24430	COG1309	transcriptional regulator
KXJ62_RS24440	COG0596	Alpha beta hydrolase
KXJ62_RS24465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KXJ62_RS24470	COG0583	DNA-binding transcription factor activity
KXJ62_RS24480	COG0372	Belongs to the citrate synthase family
KXJ62_RS24505	COG4774	siderophore transport
KXJ62_RS24510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KXJ62_RS24520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KXJ62_RS24525	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KXJ62_RS24530	COG1120	ATPase activity
KXJ62_RS24550	COG0640	Transcriptional regulator
KXJ62_RS24555	COG0431	NADPH-dependent FMN reductase
KXJ62_RS24565	COG0604	alcohol dehydrogenase
KXJ62_RS24575	COG0583	DNA-binding transcription factor activity
KXJ62_RS24580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KXJ62_RS24585	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KXJ62_RS24605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KXJ62_RS24635	COG2207	Transcriptional regulator
KXJ62_RS24640	COG0697	spore germination
KXJ62_RS24645	COG4977	sequence-specific DNA binding
KXJ62_RS24650	COG3246	L-lysine catabolic process to acetate
KXJ62_RS24655	COG0747	negative chemotaxis
KXJ62_RS24660	COG0824	Thioesterase
KXJ62_RS24660	COG1250	3-hydroxyacyl-CoA dehydrogenase
KXJ62_RS24665	COG0601	transmembrane transport
KXJ62_RS24670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS24680	COG0657	acetylesterase activity
KXJ62_RS24695	COG3177	Filamentation induced by cAMP protein fic
KXJ62_RS24730	COG1280	lysine exporter protein (LysE YggA)
KXJ62_RS24735	COG3422	double-strand break repair
KXJ62_RS24745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KXJ62_RS24780	COG3436	PFAM IS66 Orf2 family protein
KXJ62_RS24805	COG3920	Histidine kinase
KXJ62_RS24820	COG0784	Response regulator, receiver
KXJ62_RS24830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KXJ62_RS24845	COG1309	transcriptional regulator
KXJ62_RS24855	COG3177	Filamentation induced by cAMP protein fic
KXJ62_RS24860	COG1309	transcriptional regulator
KXJ62_RS24880	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS24885	COG0583	DNA-binding transcription factor activity
KXJ62_RS24890	COG1609	Transcriptional regulator
KXJ62_RS24895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ62_RS24900	COG0477	Major facilitator Superfamily
KXJ62_RS24910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ62_RS24920	COG3842	ATPase activity
KXJ62_RS24925	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS24955	COG2186	Transcriptional regulator
KXJ62_RS24965	COG0765	amino acid transport
KXJ62_RS24970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS24975	COG3842	ATPase activity
KXJ62_RS24990	COG1177	transmembrane transport
KXJ62_RS25000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KXJ62_RS25020	COG0583	DNA-binding transcription factor activity
KXJ62_RS25035	COG1177	transmembrane transport
KXJ62_RS25040	COG3842	ATPase activity
KXJ62_RS25045	COG2072	flavoprotein involved in K transport
KXJ62_RS25065	COG0534	Mate efflux family protein
KXJ62_RS25085	COG1609	Transcriptional regulator
KXJ62_RS25090	COG1082	Xylose isomerase domain protein TIM barrel
KXJ62_RS25095	COG0673	inositol 2-dehydrogenase activity
KXJ62_RS25105	COG1082	Xylose isomerase domain protein TIM barrel
KXJ62_RS25115	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS25135	COG0840	transmembrane signaling receptor activity
KXJ62_RS25145	COG4221	oxidoreductase activity
KXJ62_RS25150	COG1902	pentaerythritol trinitrate reductase activity
KXJ62_RS25155	COG0596	Alpha beta hydrolase
KXJ62_RS25165	COG3831	ATPase activity
KXJ62_RS25170	COG0071	Belongs to the small heat shock protein (HSP20) family
KXJ62_RS25185	COG0577	efflux transmembrane transporter activity
KXJ62_RS25200	COG3734	2-keto-3-deoxy-galactonokinase
KXJ62_RS25205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ62_RS25210	COG4948	Mandelate Racemase Muconate Lactonizing
KXJ62_RS25220	COG1175	transmembrane transport
KXJ62_RS25225	COG0395	ABC-type sugar transport system, permease component
KXJ62_RS25230	COG3842	ATPase activity
KXJ62_RS25235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KXJ62_RS25240	COG1414	Transcriptional regulator
KXJ62_RS25245	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ62_RS25250	COG3158	transport of potassium into the cell
KXJ62_RS25260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KXJ62_RS25290	COG0504	CTP synthase activity
KXJ62_RS25295	COG0006	proline dipeptidase activity
KXJ62_RS25300	COG4948	Mandelate Racemase Muconate Lactonizing
KXJ62_RS25305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KXJ62_RS25315	COG0765	amino acid transport
KXJ62_RS25320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KXJ62_RS25365	COG0753	catalase activity
KXJ62_RS25380	COG3685	Protein conserved in bacteria
KXJ62_RS25390	COG1309	transcriptional regulator
KXJ62_RS25395	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KXJ62_RS25400	COG2080	2 iron, 2 sulfur cluster binding
KXJ62_RS25405	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KXJ62_RS25410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KXJ62_RS25455	COG4191	Histidine kinase
KXJ62_RS25455	COG0784	Response regulator, receiver
KXJ62_RS25460	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KXJ62_RS25475	COG1278	Cold shock
KXJ62_RS25515	COG1172	Belongs to the binding-protein-dependent transport system permease family
KXJ62_RS25540	COG3920	Histidine kinase
KXJ62_RS25590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KXJ62_RS25600	COG1566	PFAM secretion protein HlyD family protein
KXJ62_RS25620	COG2207	Transcriptional regulator
KXJ62_RS25645	COG1192	Involved in chromosome partitioning
KXJ62_RS25650	COG1475	DNA binding
KXJ62_RS25655	COG0640	Transcriptional regulator
KXJ62_RS25660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KXJ62_RS25805	COG1475	DNA binding
KXJ62_RS25830	COG2824	Alkylphosphonate utilization operon protein PhnA
KXJ62_RS25855	COG5489	Protein of unknown function (DUF736)
KXJ62_RS25940	COG4172	Belongs to the ABC transporter superfamily
KXJ62_RS25945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KXJ62_RS25950	COG0601	transmembrane transport
KXJ62_RS25970	COG0010	Belongs to the arginase family
KXJ62_RS26030	COG1283	sodium-dependent phosphate transmembrane transporter activity
KXJ62_RS26035	COG0483	inositol monophosphate 1-phosphatase activity
KXJ62_RS26040	COG0584	glycerophosphoryl diester phosphodiesterase
KXJ62_RS26050	COG1176	ABC-type spermidine putrescine transport system, permease component I
KXJ62_RS26055	COG1175	transmembrane transport
KXJ62_RS26060	COG3842	ATPase activity
KXJ62_RS26080	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KXJ62_RS26090	COG1228	amidohydrolase
KXJ62_RS26100	COG1177	transmembrane transport
KXJ62_RS26110	COG3842	ATPase activity
KXJ62_RS26135	COG2986	histidine ammonia-lyase
KXJ62_RS26160	COG0765	amino acid transport
KXJ62_RS26175	COG2079	MmgE PrpD family protein
KXJ62_RS26180	COG0583	DNA-binding transcription factor activity
KXJ62_RS26200	COG3701	Conjugal transfer protein
KXJ62_RS26205	COG3846	protein secretion by the type IV secretion system
KXJ62_RS26215	COG5314	conjugation
KXJ62_RS26220	COG3451	type IV secretory pathway VirB4
KXJ62_RS26235	COG4962	Type ii secretion system protein e