locus-tag	class	description
CFBP5473_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFBP5473_RS00010	COG0640	Transcriptional regulator
CFBP5473_RS00025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFBP5473_RS00030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFBP5473_RS00035	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFBP5473_RS00045	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFBP5473_RS00050	COG1845	cytochrome c oxidase, subunit III
CFBP5473_RS00055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP5473_RS00060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFBP5473_RS00065	COG0477	Major facilitator Superfamily
CFBP5473_RS00085	COG3618	amidohydrolase
CFBP5473_RS00090	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP5473_RS00100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP5473_RS00125	COG3265	gluconokinase activity
CFBP5473_RS00135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5473_RS00140	COG0174	glutamine synthetase
CFBP5473_RS00145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5473_RS00150	COG4172	Belongs to the ABC transporter superfamily
CFBP5473_RS00165	COG4239	(ABC) transporter, permease
CFBP5473_RS00170	COG4174	ABC transporter (Permease)
CFBP5473_RS00175	COG4166	transmembrane transport
CFBP5473_RS00180	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CFBP5473_RS00185	COG1803	Methylglyoxal synthase
CFBP5473_RS00190	COG0837	glucose binding
CFBP5473_RS00195	COG1132	(ABC) transporter
CFBP5473_RS00200	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFBP5473_RS00205	COG0588	phosphoglycerate mutase activity
CFBP5473_RS00210	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP5473_RS00235	COG0572	uridine kinase
CFBP5473_RS00245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFBP5473_RS00255	COG0456	acetyltransferase
CFBP5473_RS00270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5473_RS00280	COG2813	Specifically methylates the guanine in position
CFBP5473_RS00285	COG1185	polyribonucleotide nucleotidyltransferase activity
CFBP5473_RS00290	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFBP5473_RS00295	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFBP5473_RS00300	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFBP5473_RS00305	COG3064	Membrane
CFBP5473_RS00305	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFBP5473_RS00320	COG0779	Required for maturation of 30S ribosomal subunits
CFBP5473_RS00325	COG2814	Major facilitator Superfamily
CFBP5473_RS00330	COG2951	lytic endotransglycosylase activity
CFBP5473_RS00335	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFBP5473_RS00345	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFBP5473_RS00350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFBP5473_RS00365	COG2816	NAD+ diphosphatase activity
CFBP5473_RS00375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFBP5473_RS00380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFBP5473_RS00385	COG0756	dUTP diphosphatase activity
CFBP5473_RS00395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFBP5473_RS00400	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CFBP5473_RS00405	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFBP5473_RS00420	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS00425	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS00430	COG3845	ABC transporter
CFBP5473_RS00435	COG1744	ABC transporter substrate-binding protein PnrA-like
CFBP5473_RS00440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP5473_RS00455	COG2856	Zn peptidase
CFBP5473_RS00475	COG3474	cytochrome
CFBP5473_RS00480	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CFBP5473_RS00485	COG0077	Prephenate dehydratase
CFBP5473_RS00485	COG1605	Chorismate mutase
CFBP5473_RS00490	COG0481	GTPase activity
CFBP5473_RS00510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5473_RS00515	COG0697	spore germination
CFBP5473_RS00520	COG3757	hydrolase, family 25
CFBP5473_RS00525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP5473_RS00530	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFBP5473_RS00535	COG1278	Cold shock
CFBP5473_RS00550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP5473_RS00550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP5473_RS00555	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CFBP5473_RS00585	COG2900	Belongs to the SlyX family
CFBP5473_RS00595	COG0484	heat shock protein binding
CFBP5473_RS00600	COG0443	Heat shock 70 kDa protein
CFBP5473_RS00615	COG1136	(ABC) transporter
CFBP5473_RS00630	COG0784	Response regulator, receiver
CFBP5473_RS00635	COG0784	Response regulator, receiver
CFBP5473_RS00635	COG4191	Histidine kinase
CFBP5473_RS00640	COG4251	negative regulation of phosphorylation
CFBP5473_RS00680	COG4964	Belongs to the GSP D family
CFBP5473_RS00715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP5473_RS00720	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFBP5473_RS00730	COG0791	NLP P60 protein
CFBP5473_RS00745	COG0697	spore germination
CFBP5473_RS00750	COG0402	S-adenosylhomocysteine deaminase activity
CFBP5473_RS00755	COG1228	amidohydrolase
CFBP5473_RS00760	COG2986	histidine ammonia-lyase
CFBP5473_RS00770	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFBP5473_RS00795	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5473_RS00800	COG1959	2 iron, 2 sulfur cluster binding
CFBP5473_RS00820	COG1732	Glycine betaine
CFBP5473_RS00825	COG1174	glycine betaine transport
CFBP5473_RS00830	COG1125	glycine betaine transport
CFBP5473_RS00835	COG1174	glycine betaine transport
CFBP5473_RS00840	COG2188	Transcriptional regulator
CFBP5473_RS00850	COG0848	biopolymer transport protein
CFBP5473_RS00860	COG2188	Transcriptional regulator
CFBP5473_RS00865	COG3624	Phosphonate C-P lyase system protein PhnG
CFBP5473_RS00870	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CFBP5473_RS00875	COG3626	phosphonate metabolism
CFBP5473_RS00880	COG3627	carbon phosphorus lyase activity
CFBP5473_RS00885	COG4107	phosphonate C-P lyase system protein PhnK
CFBP5473_RS00890	COG4778	phosphonate C-P lyase system protein PhnL
CFBP5473_RS00900	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFBP5473_RS00905	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CFBP5473_RS00910	COG3639	organic phosphonate transmembrane transporter activity
CFBP5473_RS00915	COG3639	organic phosphonate transmembrane transporter activity
CFBP5473_RS00920	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP5473_RS00925	COG3454	Phosphonate metabolism
CFBP5473_RS00930	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP5473_RS00975	COG1643	Atp-dependent helicase
CFBP5473_RS00985	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CFBP5473_RS01000	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFBP5473_RS01010	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFBP5473_RS01015	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFBP5473_RS01020	COG0131	Imidazoleglycerol-phosphate dehydratase
CFBP5473_RS01030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFBP5473_RS01035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFBP5473_RS01040	COG0107	imidazoleglycerol-phosphate synthase activity
CFBP5473_RS01045	COG0140	phosphoribosyl-ATP diphosphatase activity
CFBP5473_RS01050	COG1072	(Pantothenic acid kinase))
CFBP5473_RS01060	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CFBP5473_RS01065	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS01070	COG0642	Histidine kinase
CFBP5473_RS01075	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFBP5473_RS01080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP5473_RS01080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFBP5473_RS01085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP5473_RS01090	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CFBP5473_RS01095	COG2205	protein histidine kinase activity
CFBP5473_RS01100	COG3178	'Phosphotransferase
CFBP5473_RS01105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFBP5473_RS01125	COG0285	dihydrofolate synthase activity
CFBP5473_RS01130	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFBP5473_RS01135	COG0159	tryptophan synthase activity
CFBP5473_RS01140	COG0133	tryptophan synthase activity
CFBP5473_RS01145	COG0135	phosphoribosylanthranilate isomerase activity
CFBP5473_RS01160	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFBP5473_RS01200	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CFBP5473_RS01210	COG0237	dephospho-CoA kinase activity
CFBP5473_RS01215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP5473_RS01220	COG0424	maF-like protein
CFBP5473_RS01225	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CFBP5473_RS01230	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFBP5473_RS01235	COG1981	membrane
CFBP5473_RS01240	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFBP5473_RS01245	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFBP5473_RS01250	COG0445	tRNA wobble uridine modification
CFBP5473_RS01255	COG0357	Ribosomal RNA small subunit methyltransferase G
CFBP5473_RS01275	COG0501	Belongs to the peptidase M48B family
CFBP5473_RS01290	COG0138	bifunctional purine biosynthesis protein purh
CFBP5473_RS01295	COG2721	sulfolactate sulfo-lyase activity
CFBP5473_RS01305	COG1129	ABC transporter
CFBP5473_RS01310	COG4214	carbohydrate transport
CFBP5473_RS01330	COG1063	alcohol dehydrogenase
CFBP5473_RS01335	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5473_RS01350	COG1492	cobalamin metabolic process
CFBP5473_RS01415	COG1473	amidohydrolase
CFBP5473_RS01420	COG3459	Glycosyltransferase 36 associated
CFBP5473_RS01430	COG0495	leucyl-tRNA aminoacylation
CFBP5473_RS01445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFBP5473_RS01460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP5473_RS01465	COG1946	Acyl-CoA thioesterase
CFBP5473_RS01470	COG0347	Belongs to the P(II) protein family
CFBP5473_RS01475	COG0004	ammonium transporteR
CFBP5473_RS01480	COG1674	ftsk spoiiie
CFBP5473_RS01485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CFBP5473_RS01510	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS01520	COG1329	Transcriptional regulator
CFBP5473_RS01525	COG2902	Dehydrogenase
CFBP5473_RS01530	COG2270	Major facilitator Superfamily
CFBP5473_RS01540	COG0183	Belongs to the thiolase family
CFBP5473_RS01545	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS01560	COG0494	nUDIX hydrolase
CFBP5473_RS01570	COG0793	Belongs to the peptidase S41A family
CFBP5473_RS01580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFBP5473_RS01585	COG0799	negative regulation of ribosome biogenesis
CFBP5473_RS01590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFBP5473_RS01595	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFBP5473_RS01600	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFBP5473_RS01605	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFBP5473_RS01615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP5473_RS01620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFBP5473_RS01625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFBP5473_RS01650	COG0066	3-isopropylmalate dehydratase activity
CFBP5473_RS01655	COG0473	3-isopropylmalate dehydrogenase activity
CFBP5473_RS01660	COG1858	cytochrome C peroxidase
CFBP5473_RS01670	COG0625	glutathione transferase activity
CFBP5473_RS01675	COG1797	cobyrinic acid a,c-diamide synthase activity
CFBP5473_RS01680	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CFBP5473_RS01685	COG0579	oxidoreductase
CFBP5473_RS01705	COG2084	Dehydrogenase
CFBP5473_RS01710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5473_RS01715	COG0277	FAD linked oxidase domain protein
CFBP5473_RS01720	COG2186	Transcriptional regulator
CFBP5473_RS01730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP5473_RS01735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5473_RS01740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5473_RS01745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP5473_RS01755	COG1132	(ABC) transporter
CFBP5473_RS01760	COG2197	response regulator
CFBP5473_RS01765	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFBP5473_RS01770	COG1349	DNA-binding transcription factor activity
CFBP5473_RS01775	COG0738	Major facilitator superfamily
CFBP5473_RS01780	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFBP5473_RS01785	COG2885	chlorophyll binding
CFBP5473_RS01790	COG0335	large ribosomal subunit rRNA binding
CFBP5473_RS01805	COG0336	Belongs to the RNA methyltransferase TrmD family
CFBP5473_RS01810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFBP5473_RS01815	COG0228	four-way junction DNA binding
CFBP5473_RS01820	COG0287	Prephenate dehydrogenase
CFBP5473_RS01820	COG1605	Chorismate mutase
CFBP5473_RS01825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFBP5473_RS01845	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFBP5473_RS01865	COG0488	(ABC) transporter
CFBP5473_RS01875	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CFBP5473_RS01885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFBP5473_RS01890	COG0142	geranyltranstransferase activity
CFBP5473_RS01900	COG0765	amino acid transport
CFBP5473_RS01915	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFBP5473_RS01920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFBP5473_RS01925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP5473_RS01930	COG0552	protein localization to endoplasmic reticulum
CFBP5473_RS01935	COG2917	probably involved in intracellular septation
CFBP5473_RS01955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP5473_RS01960	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP5473_RS01965	COG4133	protoheme IX ABC transporter activity
CFBP5473_RS01970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFBP5473_RS01985	COG0670	Belongs to the BI1 family
CFBP5473_RS01990	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CFBP5473_RS01995	COG4181	ATPase activity
CFBP5473_RS02005	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CFBP5473_RS02010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFBP5473_RS02015	COG2154	pterin-4-alpha-carbinolamine dehydratase
CFBP5473_RS02030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CFBP5473_RS02040	COG4120	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS02045	COG1122	ATPase activity
CFBP5473_RS02050	COG1280	lysine exporter protein (LysE YggA)
CFBP5473_RS02060	COG0137	argininosuccinate synthase activity
CFBP5473_RS02075	COG0339	signal peptide processing
CFBP5473_RS02080	COG1217	gtp-binding protein TYPA
CFBP5473_RS02090	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFBP5473_RS02095	COG1872	DUF167
CFBP5473_RS02140	COG0181	hydroxymethylbilane synthase activity
CFBP5473_RS02145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFBP5473_RS02150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFBP5473_RS02205	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFBP5473_RS02210	COG0039	L-malate dehydrogenase activity
CFBP5473_RS02215	COG0045	succinate-CoA ligase (ADP-forming) activity
CFBP5473_RS02220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFBP5473_RS02225	COG0567	Dehydrogenase, E1 component
CFBP5473_RS02230	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP5473_RS02250	COG3038	cytochrome b561
CFBP5473_RS02260	COG4974	Belongs to the 'phage' integrase family
CFBP5473_RS02275	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFBP5473_RS02280	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFBP5473_RS02285	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFBP5473_RS02290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFBP5473_RS02295	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFBP5473_RS02300	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFBP5473_RS02305	COG2204	response regulator
CFBP5473_RS02310	COG5002	protein histidine kinase activity
CFBP5473_RS02315	COG2223	nitrite transmembrane transporter activity
CFBP5473_RS02325	COG0835	chemotaxis
CFBP5473_RS02340	COG0729	surface antigen
CFBP5473_RS02350	COG0156	8-amino-7-oxononanoate synthase activity
CFBP5473_RS02355	COG3443	Belongs to the bacterial solute-binding protein 9 family
CFBP5473_RS02360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFBP5473_RS02365	COG0671	phosphoesterase, PA-phosphatase related
CFBP5473_RS02405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS02410	COG0601	transmembrane transport
CFBP5473_RS02415	COG0747	negative chemotaxis
CFBP5473_RS02455	COG1234	tRNA 3'-trailer cleavage
CFBP5473_RS02460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP5473_RS02465	COG1132	(ABC) transporter
CFBP5473_RS02480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP5473_RS02490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5473_RS02495	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFBP5473_RS02510	COG2022	thiamine diphosphate biosynthetic process
CFBP5473_RS02520	COG2005	Transcriptional regulator
CFBP5473_RS02520	COG3585	molybdate ion transport
CFBP5473_RS02525	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CFBP5473_RS02530	COG4149	molybdate abc transporter
CFBP5473_RS02535	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFBP5473_RS02540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5473_RS02560	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CFBP5473_RS02565	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFBP5473_RS02575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP5473_RS02585	COG1309	transcriptional regulator
CFBP5473_RS02590	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP5473_RS02625	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP5473_RS02650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP5473_RS02655	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFBP5473_RS02670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFBP5473_RS02675	COG1414	Transcriptional regulator
CFBP5473_RS02680	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS02685	COG5487	UPF0391 membrane protein
CFBP5473_RS02690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP5473_RS02695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP5473_RS02700	COG1121	(ABC) transporter
CFBP5473_RS02720	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFBP5473_RS02725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP5473_RS02735	COG1253	flavin adenine dinucleotide binding
CFBP5473_RS02765	COG2011	ABC-type metal ion transport system permease component
CFBP5473_RS02770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFBP5473_RS02775	COG0778	Nitroreductase
CFBP5473_RS02780	COG2801	Transposase and inactivated derivatives
CFBP5473_RS02780	COG3415	Transposase
CFBP5473_RS02785	COG2115	Belongs to the xylose isomerase family
CFBP5473_RS02790	COG1070	Carbohydrate kinase
CFBP5473_RS02800	COG1054	Belongs to the UPF0176 family
CFBP5473_RS02810	COG2954	triphosphatase activity
CFBP5473_RS02815	COG0800	Aldolase
CFBP5473_RS02835	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CFBP5473_RS02845	COG0583	DNA-binding transcription factor activity
CFBP5473_RS02860	COG0840	transmembrane signaling receptor activity
CFBP5473_RS02860	COG2972	Histidine kinase
CFBP5473_RS02865	COG3047	cAMP biosynthetic process
CFBP5473_RS02890	COG0523	cobalamin synthesis protein
CFBP5473_RS02900	COG1846	Transcriptional regulator
CFBP5473_RS02905	COG1609	Transcriptional regulator
CFBP5473_RS02910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5473_RS02915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFBP5473_RS02920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP5473_RS02930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP5473_RS02965	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP5473_RS02970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5473_RS02985	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP5473_RS02985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP5473_RS03015	COG0033	Phosphoglucomutase
CFBP5473_RS03020	COG0297	glycogen (starch) synthase activity
CFBP5473_RS03025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CFBP5473_RS03030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFBP5473_RS03035	COG0058	SHG alpha-glucan phosphorylase activity
CFBP5473_RS03050	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP5473_RS03050	COG2307	Protein conserved in bacteria
CFBP5473_RS03105	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP5473_RS03110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CFBP5473_RS03115	COG0330	HflC and HflK could
CFBP5473_RS03140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP5473_RS03145	COG2951	lytic endotransglycosylase activity
CFBP5473_RS03165	COG1487	ribonuclease activity
CFBP5473_RS03175	COG0070	glutamate synthase
CFBP5473_RS03175	COG0069	glutamate synthase activity
CFBP5473_RS03175	COG0067	glutamate synthase
CFBP5473_RS03205	COG0737	Belongs to the 5'-nucleotidase family
CFBP5473_RS03215	COG5310	Homospermidine synthase
CFBP5473_RS03225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP5473_RS03240	COG3108	Peptidase M15
CFBP5473_RS03250	COG0469	pyruvate kinase activity
CFBP5473_RS03270	COG3750	Belongs to the UPF0335 family
CFBP5473_RS03290	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5473_RS03320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFBP5473_RS03325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFBP5473_RS03330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFBP5473_RS03335	COG0457	Tetratricopeptide repeat
CFBP5473_RS03340	COG0625	glutathione transferase activity
CFBP5473_RS03350	COG1132	(ABC) transporter
CFBP5473_RS03355	COG0254	rRNA binding
CFBP5473_RS03385	COG3588	fructose-bisphosphate aldolase
CFBP5473_RS03390	COG0126	phosphoglycerate kinase activity
CFBP5473_RS03395	COG3263	regulation of cellular component size
CFBP5473_RS03410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP5473_RS03455	COG1253	flavin adenine dinucleotide binding
CFBP5473_RS03465	COG1692	metallophosphoesterase
CFBP5473_RS03480	COG0217	transcriptional regulatory protein
CFBP5473_RS03490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS03495	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CFBP5473_RS03500	COG0632	four-way junction helicase activity
CFBP5473_RS03515	COG2255	four-way junction helicase activity
CFBP5473_RS03520	COG1408	metallophosphoesterase
CFBP5473_RS03535	COG0494	nUDIX hydrolase
CFBP5473_RS03545	COG0824	Thioesterase
CFBP5473_RS03565	COG0823	Involved in the tonB-independent uptake of proteins
CFBP5473_RS03570	COG2885	chlorophyll binding
CFBP5473_RS03580	COG0037	tRNA processing
CFBP5473_RS03585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP5473_RS03590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP5473_RS03595	COG3300	MHYT domain
CFBP5473_RS03595	COG5001	Diguanylate cyclase
CFBP5473_RS03610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP5473_RS03630	COG0482	sulfurtransferase activity
CFBP5473_RS03640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP5473_RS03660	COG0783	Belongs to the Dps family
CFBP5473_RS03710	COG3721	Heme iron utilization protein
CFBP5473_RS03720	COG4558	Periplasmic binding protein
CFBP5473_RS03725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5473_RS03730	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFBP5473_RS03735	COG2832	Protein of unknown function (DUF454)
CFBP5473_RS03745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFBP5473_RS03765	COG0346	lactoylglutathione lyase activity
CFBP5473_RS03775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5473_RS03775	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFBP5473_RS03780	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFBP5473_RS03780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5473_RS03785	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP5473_RS03810	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CFBP5473_RS03815	COG2351	hydroxyisourate hydrolase activity
CFBP5473_RS03830	COG4115	mRNA cleavage
CFBP5473_RS03835	COG1686	Belongs to the peptidase S11 family
CFBP5473_RS03840	COG1304	FMN binding
CFBP5473_RS03845	COG0840	transmembrane signaling receptor activity
CFBP5473_RS03850	COG0402	S-adenosylhomocysteine deaminase activity
CFBP5473_RS03860	COG0583	DNA-binding transcription factor activity
CFBP5473_RS03870	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP5473_RS03875	COG3657	addiction module killer protein
CFBP5473_RS03900	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS03905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP5473_RS03920	COG0024	Methionine aminopeptidase
CFBP5473_RS03925	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CFBP5473_RS03950	COG1160	GTP binding
CFBP5473_RS03970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5473_RS03975	COG0366	Alpha amylase catalytic
CFBP5473_RS03985	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP5473_RS04005	COG4175	Glycine betaine
CFBP5473_RS04020	COG1435	thymidine kinase activity
CFBP5473_RS04025	COG3794	PFAM blue (type 1) copper domain protein
CFBP5473_RS04040	COG2197	response regulator
CFBP5473_RS04060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFBP5473_RS04060	COG0512	Glutamine amidotransferase of anthranilate synthase
CFBP5473_RS04070	COG2801	Transposase and inactivated derivatives
CFBP5473_RS04070	COG3415	Transposase
CFBP5473_RS04090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFBP5473_RS04095	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFBP5473_RS04100	COG3416	Protein conserved in bacteria
CFBP5473_RS04110	COG0740	serine-type endopeptidase activity
CFBP5473_RS04130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP5473_RS04140	COG0564	pseudouridine synthase activity
CFBP5473_RS04150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP5473_RS04160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFBP5473_RS04230	COG1218	3'(2'),5'-bisphosphate nucleotidase
CFBP5473_RS04265	COG1660	Displays ATPase and GTPase activities
CFBP5473_RS04280	COG5002	protein histidine kinase activity
CFBP5473_RS04280	COG2198	Histidine kinase
CFBP5473_RS04280	COG0784	Response regulator, receiver
CFBP5473_RS04285	COG0174	glutamine synthetase
CFBP5473_RS04300	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS04330	COG0829	nickel cation binding
CFBP5473_RS04335	COG0831	urea catabolic process
CFBP5473_RS04340	COG3813	Protein conserved in bacteria
CFBP5473_RS04345	COG0832	Belongs to the urease beta subunit family
CFBP5473_RS04355	COG3755	Protein conserved in bacteria
CFBP5473_RS04360	COG0804	urea catabolic process
CFBP5473_RS04375	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CFBP5473_RS04380	COG0830	nickel cation binding
CFBP5473_RS04385	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFBP5473_RS04390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP5473_RS04405	COG1309	transcriptional regulator
CFBP5473_RS04420	COG2346	COG2346, Truncated hemoglobins
CFBP5473_RS04425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP5473_RS04475	COG1129	ABC transporter
CFBP5473_RS04480	COG4214	carbohydrate transport
CFBP5473_RS04485	COG4213	ABC transporter substrate-binding protein
CFBP5473_RS04510	COG4213	ABC transporter substrate-binding protein
CFBP5473_RS04520	COG4214	carbohydrate transport
CFBP5473_RS04540	COG1305	Transglutaminase-like
CFBP5473_RS04550	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP5473_RS04555	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5473_RS04565	COG2259	Doxx family
CFBP5473_RS04570	COG0784	Response regulator, receiver
CFBP5473_RS04570	COG5002	protein histidine kinase activity
CFBP5473_RS04570	COG2205	protein histidine kinase activity
CFBP5473_RS04575	COG0513	Belongs to the DEAD box helicase family
CFBP5473_RS04595	COG3135	benzoate transporter
CFBP5473_RS04600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFBP5473_RS04605	COG2801	Transposase and inactivated derivatives
CFBP5473_RS04605	COG3415	Transposase
CFBP5473_RS04615	COG0494	nUDIX hydrolase
CFBP5473_RS04620	COG0435	Glutathione S-transferase
CFBP5473_RS04630	COG0477	Major facilitator Superfamily
CFBP5473_RS04640	COG0454	-acetyltransferase
CFBP5473_RS04660	COG0714	Associated with various cellular activities
CFBP5473_RS04690	COG0408	coproporphyrinogen oxidase activity
CFBP5473_RS04715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFBP5473_RS04720	COG1132	(ABC) transporter
CFBP5473_RS04725	COG0840	transmembrane signaling receptor activity
CFBP5473_RS04730	COG1132	(ABC) transporter
CFBP5473_RS04750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CFBP5473_RS04750	COG2857	Cytochrome c1
CFBP5473_RS04755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFBP5473_RS04780	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS04805	COG0193	aminoacyl-tRNA hydrolase activity
CFBP5473_RS04820	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFBP5473_RS04830	COG5001	Diguanylate cyclase
CFBP5473_RS04830	COG3300	MHYT domain
CFBP5473_RS04840	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5473_RS04845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CFBP5473_RS04855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFBP5473_RS04870	COG1496	oxidoreductase activity
CFBP5473_RS04880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFBP5473_RS04900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP5473_RS04905	COG2205	protein histidine kinase activity
CFBP5473_RS04910	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS04915	COG1846	Transcriptional regulator
CFBP5473_RS04925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP5473_RS04940	COG1278	Cold shock
CFBP5473_RS04955	COG2199	diguanylate cyclase activity
CFBP5473_RS04955	COG2200	EAL domain
CFBP5473_RS04970	COG0387	Pfam Sodium calcium exchanger
CFBP5473_RS04990	COG1902	pentaerythritol trinitrate reductase activity
CFBP5473_RS05000	COG0583	DNA-binding transcription factor activity
CFBP5473_RS05005	COG0492	ferredoxin-NADP+ reductase activity
CFBP5473_RS05010	COG1522	sequence-specific DNA binding
CFBP5473_RS05020	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFBP5473_RS05025	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFBP5473_RS05030	COG1088	dTDP-glucose 4,6-dehydratase activity
CFBP5473_RS05035	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CFBP5473_RS05045	COG0463	Glycosyl transferase, family 2
CFBP5473_RS05050	COG0438	transferase activity, transferring glycosyl groups
CFBP5473_RS05055	COG0438	transferase activity, transferring glycosyl groups
CFBP5473_RS05060	COG0438	transferase activity, transferring glycosyl groups
CFBP5473_RS05065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFBP5473_RS05075	COG1573	uracil-dna glycosylase
CFBP5473_RS05085	COG0477	Major facilitator Superfamily
CFBP5473_RS05095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFBP5473_RS05105	COG2321	neutral zinc metallopeptidase
CFBP5473_RS05120	COG0534	Mate efflux family protein
CFBP5473_RS05125	COG0505	Belongs to the CarA family
CFBP5473_RS05145	COG0358	DNA primase activity
CFBP5473_RS05150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP5473_RS05165	COG0432	Pfam Uncharacterised protein family UPF0047
CFBP5473_RS05175	COG2968	Membrane
CFBP5473_RS05210	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFBP5473_RS05220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFBP5473_RS05225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP5473_RS05235	COG0477	Major facilitator Superfamily
CFBP5473_RS05245	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CFBP5473_RS05255	COG3842	ATPase activity
CFBP5473_RS05285	COG0531	amino acid
CFBP5473_RS05290	COG0174	glutamine synthetase
CFBP5473_RS05325	COG2814	Major facilitator Superfamily
CFBP5473_RS05330	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5473_RS05365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP5473_RS05385	COG0840	transmembrane signaling receptor activity
CFBP5473_RS05440	COG3023	N-Acetylmuramoyl-L-alanine amidase
CFBP5473_RS05490	COG2001	Belongs to the MraZ family
CFBP5473_RS05495	COG0275	rRNA processing
CFBP5473_RS05510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFBP5473_RS05520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFBP5473_RS05525	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFBP5473_RS05535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFBP5473_RS05540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFBP5473_RS05545	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFBP5473_RS05550	COG0477	Major facilitator Superfamily
CFBP5473_RS05570	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFBP5473_RS05575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFBP5473_RS05580	COG0849	cell division
CFBP5473_RS05585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP5473_RS05595	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP5473_RS05600	COG0497	DNA recombination
CFBP5473_RS05610	COG1280	lysine exporter protein (LysE YggA)
CFBP5473_RS05625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFBP5473_RS05635	COG1247	-acetyltransferase
CFBP5473_RS05640	COG0697	spore germination
CFBP5473_RS05660	COG0835	chemotaxis
CFBP5473_RS05675	COG2264	protein methyltransferase activity
CFBP5473_RS05680	COG0006	proline dipeptidase activity
CFBP5473_RS05700	COG1335	isochorismatase
CFBP5473_RS05735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5473_RS05745	COG0277	FAD linked oxidase domain protein
CFBP5473_RS05800	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFBP5473_RS05810	COG0330	HflC and HflK could
CFBP5473_RS05815	COG0330	HflC and HflK could
CFBP5473_RS05840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS05845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5473_RS05855	COG1116	anion transmembrane transporter activity
CFBP5473_RS05865	COG0560	Phosphoserine phosphatase
CFBP5473_RS05870	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFBP5473_RS05885	COG0028	Belongs to the TPP enzyme family
CFBP5473_RS05890	COG0440	acetolactate synthase activity
CFBP5473_RS05900	COG0840	transmembrane signaling receptor activity
CFBP5473_RS05905	COG0656	L-ascorbic acid biosynthetic process
CFBP5473_RS05915	COG0840	transmembrane signaling receptor activity
CFBP5473_RS05920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP5473_RS05930	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFBP5473_RS05940	COG1064	alcohol dehydrogenase
CFBP5473_RS05945	COG2207	Transcriptional regulator
CFBP5473_RS05950	COG0702	epimerase
CFBP5473_RS05955	COG1733	regulation of RNA biosynthetic process
CFBP5473_RS05965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFBP5473_RS05980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5473_RS05985	COG0384	phenazine biosynthesis protein PhzF
CFBP5473_RS06030	COG0484	heat shock protein binding
CFBP5473_RS06050	COG2382	esterase
CFBP5473_RS06055	COG0556	nucleotide-excision repair
CFBP5473_RS06105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP5473_RS06130	COG0861	Integral membrane protein TerC family
CFBP5473_RS06135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP5473_RS06155	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFBP5473_RS06165	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFBP5473_RS06170	COG0081	regulation of translation
CFBP5473_RS06175	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFBP5473_RS06180	COG0222	ribosome binding
CFBP5473_RS06185	COG0085	RNA polymerase activity
CFBP5473_RS06190	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFBP5473_RS06200	COG0583	DNA-binding transcription factor activity
CFBP5473_RS06230	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFBP5473_RS06235	COG0049	tRNA binding
CFBP5473_RS06240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFBP5473_RS06245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP5473_RS06250	COG0051	transcription antitermination factor activity, RNA binding
CFBP5473_RS06255	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFBP5473_RS06260	COG0088	Forms part of the polypeptide exit tunnel
CFBP5473_RS06265	COG0089	rRNA binding
CFBP5473_RS06270	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFBP5473_RS06275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFBP5473_RS06280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFBP5473_RS06285	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFBP5473_RS06290	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFBP5473_RS06295	COG0255	Belongs to the universal ribosomal protein uL29 family
CFBP5473_RS06300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFBP5473_RS06305	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFBP5473_RS06310	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFBP5473_RS06315	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFBP5473_RS06320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFBP5473_RS06325	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFBP5473_RS06330	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFBP5473_RS06335	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFBP5473_RS06340	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFBP5473_RS06345	COG1841	ribosomal large subunit assembly
CFBP5473_RS06350	COG0200	Binds to the 23S rRNA
CFBP5473_RS06355	COG0201	protein transport
CFBP5473_RS06360	COG0563	adenylate kinase activity
CFBP5473_RS06365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFBP5473_RS06370	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFBP5473_RS06375	COG0202	RNA polymerase activity
CFBP5473_RS06380	COG0203	ribosomal protein L17
CFBP5473_RS06410	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CFBP5473_RS06415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFBP5473_RS06420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5473_RS06430	COG0129	dihydroxy-acid dehydratase activity
CFBP5473_RS06465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP5473_RS06470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFBP5473_RS06495	COG1131	(ABC) transporter
CFBP5473_RS06500	COG0842	Transport permease protein
CFBP5473_RS06535	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CFBP5473_RS06540	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CFBP5473_RS06545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CFBP5473_RS06550	COG2202	Pas domain
CFBP5473_RS06550	COG2205	protein histidine kinase activity
CFBP5473_RS06560	COG1573	uracil-dna glycosylase
CFBP5473_RS06565	COG1522	sequence-specific DNA binding
CFBP5473_RS06575	COG5425	PFAM Usg family protein
CFBP5473_RS06590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5473_RS06600	COG2313	pseudouridylate synthase activity
CFBP5473_RS06605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5473_RS06610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFBP5473_RS06615	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFBP5473_RS06630	COG0321	lipoyl(octanoyl) transferase activity
CFBP5473_RS06650	COG0538	isocitrate dehydrogenase activity
CFBP5473_RS06660	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CFBP5473_RS06665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFBP5473_RS06680	COG1280	lysine exporter protein (LysE YggA)
CFBP5473_RS06705	COG0861	Integral membrane protein TerC family
CFBP5473_RS06710	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFBP5473_RS06715	COG0546	phosphoglycolate phosphatase activity
CFBP5473_RS06720	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFBP5473_RS06735	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CFBP5473_RS06740	COG2852	Protein conserved in bacteria
CFBP5473_RS06745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFBP5473_RS06755	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CFBP5473_RS06765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5473_RS06780	COG0047	phosphoribosylformylglycinamidine synthase activity
CFBP5473_RS06785	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP5473_RS06790	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP5473_RS06810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFBP5473_RS06830	COG0513	Belongs to the DEAD box helicase family
CFBP5473_RS06835	COG0739	heme binding
CFBP5473_RS06840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFBP5473_RS06850	COG0525	valine-tRNA ligase activity
CFBP5473_RS06875	COG0840	transmembrane signaling receptor activity
CFBP5473_RS06885	COG0316	Belongs to the HesB IscA family
CFBP5473_RS06890	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CFBP5473_RS06895	COG0018	arginyl-trna synthetase
CFBP5473_RS06905	COG1472	Belongs to the glycosyl hydrolase 3 family
CFBP5473_RS06910	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFBP5473_RS06915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFBP5473_RS06920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP5473_RS06925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP5473_RS06930	COG0805	protein transport
CFBP5473_RS06935	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP5473_RS06940	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CFBP5473_RS06945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP5473_RS06955	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFBP5473_RS06960	COG0746	molybdenum cofactor guanylyltransferase activity
CFBP5473_RS06965	COG2814	Major facilitator Superfamily
CFBP5473_RS06970	COG0697	spore germination
CFBP5473_RS06975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFBP5473_RS06985	COG0475	glutathione-regulated potassium exporter activity
CFBP5473_RS06985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP5473_RS06995	COG3706	GGDEF domain
CFBP5473_RS07000	COG0114	fumarate hydratase activity
CFBP5473_RS07005	COG2989	Protein conserved in bacteria
CFBP5473_RS07010	COG2066	Belongs to the glutaminase family
CFBP5473_RS07015	COG0037	tRNA processing
CFBP5473_RS07020	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5473_RS07025	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5473_RS07030	COG2814	Major facilitator Superfamily
CFBP5473_RS07060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP5473_RS07070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFBP5473_RS07085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFBP5473_RS07090	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFBP5473_RS07105	COG2945	thiolester hydrolase activity
CFBP5473_RS07110	COG1104	cysteine desulfurase activity
CFBP5473_RS07115	COG0719	Fe-S assembly protein
CFBP5473_RS07120	COG0396	ATPase activity
CFBP5473_RS07125	COG0719	Fe-S assembly protein
CFBP5473_RS07130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFBP5473_RS07135	COG2151	metal-sulfur cluster biosynthetic enzyme
CFBP5473_RS07140	COG0316	Belongs to the HesB IscA family
CFBP5473_RS07150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFBP5473_RS07155	COG0577	efflux transmembrane transporter activity
CFBP5473_RS07155	COG1136	(ABC) transporter
CFBP5473_RS07160	COG0577	efflux transmembrane transporter activity
CFBP5473_RS07160	COG1136	(ABC) transporter
CFBP5473_RS07165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5473_RS07195	COG0537	adenosine 5'-monophosphoramidase activity
CFBP5473_RS07220	COG0052	Belongs to the universal ribosomal protein uS2 family
CFBP5473_RS07225	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFBP5473_RS07230	COG0528	UMP kinase activity
CFBP5473_RS07235	COG0233	cytoplasmic translational termination
CFBP5473_RS07240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFBP5473_RS07250	COG0750	zinc metalloprotease
CFBP5473_RS07255	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP5473_RS07260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP5473_RS07265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP5473_RS07270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP5473_RS07275	COG3494	Protein of unknown function (DUF1009)
CFBP5473_RS07280	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP5473_RS07295	COG1530	ribonuclease E activity
CFBP5473_RS07305	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP5473_RS07325	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFBP5473_RS07330	COG0384	phenazine biosynthesis protein PhzF
CFBP5473_RS07365	COG3264	Mechanosensitive ion channel
CFBP5473_RS07365	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CFBP5473_RS07380	COG0303	'Molybdopterin
CFBP5473_RS07390	COG0315	cyclic pyranopterin monophosphate synthase activity
CFBP5473_RS07395	COG0134	indole-3-glycerol-phosphate synthase activity
CFBP5473_RS07400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFBP5473_RS07420	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFBP5473_RS07435	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFBP5473_RS07440	COG0343	queuine tRNA-ribosyltransferase activity
CFBP5473_RS07445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFBP5473_RS07445	COG0512	Glutamine amidotransferase of anthranilate synthase
CFBP5473_RS07455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFBP5473_RS07465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFBP5473_RS07475	COG0697	spore germination
CFBP5473_RS07500	COG0174	glutamine synthetase
CFBP5473_RS07505	COG0347	Belongs to the P(II) protein family
CFBP5473_RS07510	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFBP5473_RS07510	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFBP5473_RS07520	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS07535	COG0583	DNA-binding transcription factor activity
CFBP5473_RS07560	COG1760	l-serine dehydratase
CFBP5473_RS07600	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP5473_RS07605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFBP5473_RS07610	COG0302	gtp cyclohydrolase
CFBP5473_RS07620	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFBP5473_RS07630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFBP5473_RS07670	COG0628	permease
CFBP5473_RS07675	COG1132	(ABC) transporter
CFBP5473_RS07680	COG0523	cobalamin synthesis protein
CFBP5473_RS07690	COG1121	(ABC) transporter
CFBP5473_RS07695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP5473_RS07705	COG3609	addiction module antidote protein, CC2985 family
CFBP5473_RS07725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFBP5473_RS07740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFBP5473_RS07745	COG0629	single-stranded DNA binding
CFBP5473_RS07760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFBP5473_RS07765	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP5473_RS07765	COG0022	dehydrogenase e1 component
CFBP5473_RS07770	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP5473_RS07780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFBP5473_RS07800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFBP5473_RS07815	COG0697	spore germination
CFBP5473_RS07820	COG2207	Transcriptional regulator
CFBP5473_RS07850	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFBP5473_RS07850	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFBP5473_RS07860	COG3852	Histidine kinase
CFBP5473_RS07865	COG2204	response regulator
CFBP5473_RS07870	COG5000	phosphorelay sensor kinase activity
CFBP5473_RS07875	COG2204	response regulator
CFBP5473_RS07880	COG0569	domain protein
CFBP5473_RS07885	COG1923	regulation of RNA biosynthetic process
CFBP5473_RS07890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFBP5473_RS07900	COG3956	TIGRFAM MazG family protein
CFBP5473_RS07910	COG1648	precorrin-2 dehydrogenase activity
CFBP5473_RS07910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP5473_RS07950	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP5473_RS07950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP5473_RS07955	COG0509	glycine decarboxylation via glycine cleavage system
CFBP5473_RS07960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP5473_RS07990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFBP5473_RS08000	COG0546	phosphoglycolate phosphatase activity
CFBP5473_RS08015	COG2814	Major facilitator Superfamily
CFBP5473_RS08030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5473_RS08040	COG0321	lipoyl(octanoyl) transferase activity
CFBP5473_RS08040	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CFBP5473_RS08045	COG0084	hydrolase, TatD family'
CFBP5473_RS08050	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP5473_RS08065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFBP5473_RS08070	COG1686	Belongs to the peptidase S11 family
CFBP5473_RS08095	COG3237	CsbD-like
CFBP5473_RS08100	COG2197	response regulator
CFBP5473_RS08105	COG1671	Belongs to the UPF0178 family
CFBP5473_RS08115	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CFBP5473_RS08120	COG1864	DNA RNA non-specific endonuclease
CFBP5473_RS08120	COG3591	Belongs to the peptidase S1B family
CFBP5473_RS08175	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP5473_RS08180	COG2095	MarC family integral membrane protein
CFBP5473_RS08185	COG1125	glycine betaine transport
CFBP5473_RS08185	COG0517	IMP dehydrogenase activity
CFBP5473_RS08195	COG0346	lactoylglutathione lyase activity
CFBP5473_RS08200	COG1278	Cold shock
CFBP5473_RS08240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFBP5473_RS08245	COG2197	response regulator
CFBP5473_RS08265	COG0504	CTP synthase activity
CFBP5473_RS08275	COG0149	triose-phosphate isomerase activity
CFBP5473_RS08285	COG0187	DNA topoisomerase II activity
CFBP5473_RS08290	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CFBP5473_RS08300	COG0667	Aldo Keto reductase
CFBP5473_RS08315	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFBP5473_RS08370	COG3161	chorismate lyase activity
CFBP5473_RS08390	COG5001	Diguanylate cyclase
CFBP5473_RS08390	COG3300	MHYT domain
CFBP5473_RS08405	COG2239	Acts as a magnesium transporter
CFBP5473_RS08410	COG0243	molybdopterin cofactor binding
CFBP5473_RS08420	COG0242	peptide deformylase activity
CFBP5473_RS08440	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS08450	COG3845	ABC transporter
CFBP5473_RS08455	COG1183	phosphatidylcholine synthase activity
CFBP5473_RS08460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP5473_RS08465	COG0679	Auxin Efflux Carrier
CFBP5473_RS08470	COG0785	Cytochrome C biogenesis protein
CFBP5473_RS08485	COG0148	phosphopyruvate hydratase activity
CFBP5473_RS08490	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CFBP5473_RS08495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFBP5473_RS08515	COG0372	Belongs to the citrate synthase family
CFBP5473_RS08525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CFBP5473_RS08525	COG3218	ABC-type transport auxiliary lipoprotein component
CFBP5473_RS08535	COG1127	ABC transporter
CFBP5473_RS08540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFBP5473_RS08545	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5473_RS08555	COG0280	phosphate acetyltransferase
CFBP5473_RS08555	COG0281	malic enzyme
CFBP5473_RS08565	COG0778	Nitroreductase
CFBP5473_RS08570	COG0823	Involved in the tonB-independent uptake of proteins
CFBP5473_RS08580	COG1368	sulfuric ester hydrolase activity
CFBP5473_RS08605	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFBP5473_RS08660	COG1862	Preprotein translocase
CFBP5473_RS08685	COG3106	COG3106 Predicted ATPase
CFBP5473_RS08690	COG3768	UPF0283 membrane protein
CFBP5473_RS08700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFBP5473_RS08705	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFBP5473_RS08710	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFBP5473_RS08720	COG0633	Ferredoxin
CFBP5473_RS08740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP5473_RS08765	COG0655	NAD(P)H dehydrogenase (quinone) activity
CFBP5473_RS08770	COG1058	Belongs to the CinA family
CFBP5473_RS08770	COG1546	Belongs to the CinA family
CFBP5473_RS08775	COG0589	response to stress
CFBP5473_RS08780	COG1126	abc transporter atp-binding protein
CFBP5473_RS08785	COG0765	amino acid transport
CFBP5473_RS08790	COG4597	amino acid ABC transporter
CFBP5473_RS08795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5473_RS08800	COG0626	cystathionine gamma-synthase activity
CFBP5473_RS08815	COG2267	carboxylic ester hydrolase activity
CFBP5473_RS08840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFBP5473_RS08850	COG1238	metal cluster binding
CFBP5473_RS08865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFBP5473_RS08875	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS08880	COG0784	Response regulator, receiver
CFBP5473_RS08880	COG4191	Histidine kinase
CFBP5473_RS08885	COG3920	Histidine kinase
CFBP5473_RS08890	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS08895	COG0436	Aminotransferase
CFBP5473_RS08905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP5473_RS08910	COG0511	ligase activity, forming carbon-carbon bonds
CFBP5473_RS08915	COG0439	Biotin carboxylase
CFBP5473_RS08920	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CFBP5473_RS08945	COG0456	acetyltransferase
CFBP5473_RS08950	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP5473_RS08970	COG0456	acetyltransferase
CFBP5473_RS08975	COG0154	amidase activity
CFBP5473_RS08980	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP5473_RS08990	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CFBP5473_RS08995	COG2824	Alkylphosphonate utilization operon protein PhnA
CFBP5473_RS09000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFBP5473_RS09025	COG1960	acyl-CoA dehydrogenase activity
CFBP5473_RS09030	COG0540	Belongs to the ATCase OTCase family
CFBP5473_RS09040	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CFBP5473_RS09045	COG0758	DNA mediated transformation
CFBP5473_RS09055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFBP5473_RS09060	COG0557	exoribonuclease II activity
CFBP5473_RS09080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFBP5473_RS09095	COG0784	Response regulator, receiver
CFBP5473_RS09110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP5473_RS09130	COG1136	(ABC) transporter
CFBP5473_RS09140	COG0442	prolyl-tRNA aminoacylation
CFBP5473_RS09150	COG0346	lactoylglutathione lyase activity
CFBP5473_RS09165	COG1007	ATP synthesis coupled electron transport
CFBP5473_RS09190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5473_RS09195	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CFBP5473_RS09205	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CFBP5473_RS09210	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CFBP5473_RS09220	COG0649	NAD binding
CFBP5473_RS09230	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5473_RS09235	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5473_RS09240	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5473_RS09260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5473_RS09265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5473_RS09270	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5473_RS09275	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP5473_RS09285	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFBP5473_RS09290	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFBP5473_RS09295	COG0740	serine-type endopeptidase activity
CFBP5473_RS09305	COG0405	Gamma-glutamyltransferase
CFBP5473_RS09315	COG2124	cytochrome p450
CFBP5473_RS09335	COG1832	CoA-binding protein
CFBP5473_RS09345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFBP5473_RS09350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFBP5473_RS09355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP5473_RS09355	COG2755	lipolytic protein G-D-S-L family
CFBP5473_RS09360	COG0010	Belongs to the arginase family
CFBP5473_RS09365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFBP5473_RS09375	COG1612	heme a metabolic process
CFBP5473_RS09410	COG2963	transposase activity
CFBP5473_RS09415	COG3436	PFAM IS66 Orf2 family protein
CFBP5473_RS09420	COG4372	Transposase
CFBP5473_RS09445	COG1238	metal cluster binding
CFBP5473_RS09450	COG3932	Exopolysaccharide synthesis, ExoD
CFBP5473_RS09465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP5473_RS09510	COG0415	Belongs to the DNA photolyase family
CFBP5473_RS09520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFBP5473_RS09525	COG2897	thiosulfate sulfurtransferase activity
CFBP5473_RS09545	COG0737	Belongs to the 5'-nucleotidase family
CFBP5473_RS09560	COG0436	Aminotransferase
CFBP5473_RS09595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP5473_RS09600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP5473_RS09605	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP5473_RS09610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5473_RS09615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP5473_RS09625	COG1309	transcriptional regulator
CFBP5473_RS09650	COG3243	poly(R)-hydroxyalkanoic acid synthase
CFBP5473_RS09655	COG1489	DNA binding
CFBP5473_RS09660	COG0024	Methionine aminopeptidase
CFBP5473_RS09665	COG2003	Belongs to the UPF0758 family
CFBP5473_RS09680	COG0583	DNA-binding transcription factor activity
CFBP5473_RS09685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFBP5473_RS09695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFBP5473_RS09700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFBP5473_RS09725	COG0776	regulation of translation
CFBP5473_RS09730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFBP5473_RS09735	COG0416	fatty acid biosynthetic process
CFBP5473_RS09775	COG0105	UTP biosynthetic process
CFBP5473_RS09785	COG5002	protein histidine kinase activity
CFBP5473_RS09785	COG5001	Diguanylate cyclase
CFBP5473_RS09785	COG3447	MASE1 domain protein
CFBP5473_RS09790	COG0488	(ABC) transporter
CFBP5473_RS09800	COG0726	polysaccharide deacetylase
CFBP5473_RS09820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP5473_RS09835	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CFBP5473_RS09845	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP5473_RS09850	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFBP5473_RS09865	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CFBP5473_RS09870	COG0194	GDP metabolic process
CFBP5473_RS09875	COG1561	YicC-like family, N-terminal region
CFBP5473_RS09880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFBP5473_RS09885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP5473_RS09890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5473_RS09900	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CFBP5473_RS09905	COG0667	Aldo Keto reductase
CFBP5473_RS09925	COG0360	Binds together with S18 to 16S ribosomal RNA
CFBP5473_RS09930	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFBP5473_RS09940	COG0359	binds to the 23S rRNA
CFBP5473_RS09980	COG5265	(ABC) transporter
CFBP5473_RS09985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP5473_RS10005	COG1286	toxin biosynthetic process
CFBP5473_RS10010	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFBP5473_RS10025	COG4221	oxidoreductase activity
CFBP5473_RS10030	COG0215	cysteine-tRNA ligase activity
CFBP5473_RS10045	COG2852	Protein conserved in bacteria
CFBP5473_RS10080	COG1652	LysM domain
CFBP5473_RS10085	COG5265	(ABC) transporter
CFBP5473_RS10090	COG0688	phosphatidylethanolamine metabolic process
CFBP5473_RS10095	COG1183	phosphatidylcholine synthase activity
CFBP5473_RS10100	COG3706	GGDEF domain
CFBP5473_RS10110	COG1742	UPF0060 membrane protein
CFBP5473_RS10120	COG0494	nUDIX hydrolase
CFBP5473_RS10145	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CFBP5473_RS10160	COG0668	transmembrane transport
CFBP5473_RS10175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5473_RS10190	COG0346	lactoylglutathione lyase activity
CFBP5473_RS10200	COG1418	mRNA catabolic process
CFBP5473_RS10220	COG1381	Involved in DNA repair and RecF pathway recombination
CFBP5473_RS10225	COG0784	Response regulator, receiver
CFBP5473_RS10230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP5473_RS10235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFBP5473_RS10240	COG0571	ribonuclease III activity
CFBP5473_RS10245	COG0681	Belongs to the peptidase S26 family
CFBP5473_RS10250	COG0736	holo-[acyl-carrier-protein] synthase activity
CFBP5473_RS10270	COG1758	RNA polymerase activity
CFBP5473_RS10280	COG0840	transmembrane signaling receptor activity
CFBP5473_RS10290	COG5001	Diguanylate cyclase
CFBP5473_RS10300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFBP5473_RS10305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5473_RS10310	COG0741	lytic transglycosylase activity
CFBP5473_RS10350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP5473_RS10385	COG2382	esterase
CFBP5473_RS10400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFBP5473_RS10420	COG0463	Glycosyl transferase, family 2
CFBP5473_RS10440	COG2814	Major facilitator Superfamily
CFBP5473_RS10445	COG2239	Acts as a magnesium transporter
CFBP5473_RS10460	COG1968	undecaprenyl-diphosphatase activity
CFBP5473_RS10470	COG1733	regulation of RNA biosynthetic process
CFBP5473_RS10485	COG2944	sequence-specific DNA binding
CFBP5473_RS10510	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS10535	COG0443	Heat shock 70 kDa protein
CFBP5473_RS10570	COG0840	transmembrane signaling receptor activity
CFBP5473_RS10575	COG0308	aminopeptidase N
CFBP5473_RS10580	COG2205	protein histidine kinase activity
CFBP5473_RS10580	COG2202	Pas domain
CFBP5473_RS10585	COG1408	metallophosphoesterase
CFBP5473_RS10600	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFBP5473_RS10605	COG2205	protein histidine kinase activity
CFBP5473_RS10610	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS10615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP5473_RS10620	COG3088	subunit of a heme lyase
CFBP5473_RS10625	COG1138	Cytochrome C-type biogenesis protein
CFBP5473_RS10630	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CFBP5473_RS10635	COG4235	cytochrome complex assembly
CFBP5473_RS10725	COG3415	Transposase
CFBP5473_RS10725	COG2801	Transposase and inactivated derivatives
CFBP5473_RS10755	COG4695	Portal protein
CFBP5473_RS10765	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CFBP5473_RS10810	COG1621	beta-fructofuranosidase activity
CFBP5473_RS10830	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFBP5473_RS10840	COG3041	Addiction module toxin RelE StbE family
CFBP5473_RS10845	COG3077	Addiction module antitoxin, RelB DinJ family
CFBP5473_RS10855	COG0789	Transcriptional regulator
CFBP5473_RS10875	COG2983	Belongs to the UPF0260 family
CFBP5473_RS10880	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP5473_RS10895	COG0583	DNA-binding transcription factor activity
CFBP5473_RS10910	COG2801	Transposase and inactivated derivatives
CFBP5473_RS10910	COG3415	Transposase
CFBP5473_RS10955	COG0840	transmembrane signaling receptor activity
CFBP5473_RS10960	COG0835	chemotaxis
CFBP5473_RS10970	COG2801	Transposase and inactivated derivatives
CFBP5473_RS10970	COG3415	Transposase
CFBP5473_RS10980	COG2205	protein histidine kinase activity
CFBP5473_RS10990	COG2166	iron-sulfur cluster assembly
CFBP5473_RS11015	COG4957	zinc ion binding
CFBP5473_RS11020	COG1320	monovalent cation:proton antiporter activity
CFBP5473_RS11025	COG2212	antiporter activity
CFBP5473_RS11030	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP5473_RS11035	COG0651	ATP synthesis coupled electron transport
CFBP5473_RS11040	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP5473_RS11045	COG2111	Na H antiporter
CFBP5473_RS11050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFBP5473_RS11050	COG2111	Na H antiporter
CFBP5473_RS11055	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP5473_RS11075	COG1272	protein, Hemolysin III
CFBP5473_RS11085	COG2514	catechol 2,3-dioxygenase activity
CFBP5473_RS11110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5473_RS11140	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5473_RS11170	COG0789	Transcriptional regulator
CFBP5473_RS11185	COG0456	acetyltransferase
CFBP5473_RS11210	COG0840	transmembrane signaling receptor activity
CFBP5473_RS11210	COG2972	Histidine kinase
CFBP5473_RS11215	COG2010	Cytochrome c
CFBP5473_RS11220	COG3909	cytochrome
CFBP5473_RS11235	COG0433	COG0433 Predicted ATPase
CFBP5473_RS11245	COG1733	regulation of RNA biosynthetic process
CFBP5473_RS11250	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CFBP5473_RS11255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP5473_RS11275	COG0583	DNA-binding transcription factor activity
CFBP5473_RS11300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP5473_RS11305	COG4106	trans-aconitate 2-methyltransferase activity
CFBP5473_RS11315	COG2378	regulation of single-species biofilm formation
CFBP5473_RS11325	COG0656	L-ascorbic acid biosynthetic process
CFBP5473_RS11370	COG1764	response to oxidative stress
CFBP5473_RS11375	COG1846	Transcriptional regulator
CFBP5473_RS11380	COG3609	addiction module antidote protein, CC2985 family
CFBP5473_RS11395	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5473_RS11400	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5473_RS11410	COG1793	dna ligase
CFBP5473_RS11425	COG0477	Major facilitator Superfamily
CFBP5473_RS11435	COG5001	Diguanylate cyclase
CFBP5473_RS11435	COG3300	MHYT domain
CFBP5473_RS11470	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CFBP5473_RS11475	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5473_RS11480	COG1309	transcriptional regulator
CFBP5473_RS11490	COG2199	diguanylate cyclase activity
CFBP5473_RS11490	COG2203	Gaf domain
CFBP5473_RS11490	COG2200	EAL domain
CFBP5473_RS11510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP5473_RS11515	COG4208	sulfate ABC transporter
CFBP5473_RS11520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP5473_RS11525	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CFBP5473_RS11530	COG0175	sulfate reduction
CFBP5473_RS11535	COG0175	sulfate reduction
CFBP5473_RS11540	COG2895	sulfate adenylyltransferase (ATP) activity
CFBP5473_RS11555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFBP5473_RS11580	COG0579	oxidoreductase
CFBP5473_RS11600	COG1487	ribonuclease activity
CFBP5473_RS11620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFBP5473_RS11620	COG0574	Belongs to the PEP-utilizing enzyme family
CFBP5473_RS11625	COG2514	catechol 2,3-dioxygenase activity
CFBP5473_RS11645	COG0840	transmembrane signaling receptor activity
CFBP5473_RS11650	COG1196	nuclear chromosome segregation
CFBP5473_RS11655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFBP5473_RS11680	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CFBP5473_RS11695	COG1268	BioY protein
CFBP5473_RS11705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5473_RS11720	COG0612	Peptidase, M16
CFBP5473_RS11725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP5473_RS11745	COG1678	Uncharacterized ACR, COG1678
CFBP5473_RS11755	COG0678	peroxiredoxin activity
CFBP5473_RS11755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFBP5473_RS11765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP5473_RS11770	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFBP5473_RS11775	COG3385	transposase activity
CFBP5473_RS11785	COG0328	RNA-DNA hybrid ribonuclease activity
CFBP5473_RS11790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFBP5473_RS11795	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CFBP5473_RS11800	COG3346	SURF1 family
CFBP5473_RS11815	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CFBP5473_RS11825	COG0109	protoheme IX farnesyltransferase activity
CFBP5473_RS11830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP5473_RS11845	COG0312	modulator of DNA gyrase
CFBP5473_RS11865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5473_RS11875	COG0259	pyridoxamine-phosphate oxidase activity
CFBP5473_RS11885	COG0484	heat shock protein binding
CFBP5473_RS11890	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP5473_RS11905	COG5001	Diguanylate cyclase
CFBP5473_RS11910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFBP5473_RS11920	COG3214	Protein conserved in bacteria
CFBP5473_RS11925	COG1122	ATPase activity
CFBP5473_RS11930	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFBP5473_RS11935	COG1268	BioY protein
CFBP5473_RS11940	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFBP5473_RS11945	COG1722	exodeoxyribonuclease VII activity
CFBP5473_RS11955	COG1741	Belongs to the pirin family
CFBP5473_RS11960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFBP5473_RS11985	COG0840	transmembrane signaling receptor activity
CFBP5473_RS11995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFBP5473_RS12010	COG1960	acyl-CoA dehydrogenase activity
CFBP5473_RS12035	COG4638	Rieske (2fe-2S)
CFBP5473_RS12045	COG0009	L-threonylcarbamoyladenylate synthase
CFBP5473_RS12060	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CFBP5473_RS12065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP5473_RS12070	COG2183	response to ionizing radiation
CFBP5473_RS12075	COG0151	Belongs to the GarS family
CFBP5473_RS12085	COG0840	transmembrane signaling receptor activity
CFBP5473_RS12090	COG1683	Conserved Protein
CFBP5473_RS12105	COG0751	glycine-tRNA ligase activity
CFBP5473_RS12115	COG0752	glycyl-tRNA synthetase alpha subunit
CFBP5473_RS12120	COG1704	LemA family
CFBP5473_RS12125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFBP5473_RS12145	COG2827	Endonuclease containing a URI domain
CFBP5473_RS12160	COG0142	geranyltranstransferase activity
CFBP5473_RS12170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFBP5473_RS12175	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFBP5473_RS12190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFBP5473_RS12195	COG0840	transmembrane signaling receptor activity
CFBP5473_RS12200	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP5473_RS12205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP5473_RS12215	COG0356	it plays a direct role in the translocation of protons across the membrane
CFBP5473_RS12230	COG3158	transport of potassium into the cell
CFBP5473_RS12250	COG2197	response regulator
CFBP5473_RS12255	COG1414	Transcriptional regulator
CFBP5473_RS12260	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS12265	COG3734	2-keto-3-deoxy-galactonokinase
CFBP5473_RS12270	COG0800	Aldolase
CFBP5473_RS12275	COG3386	PFAM SMP-30 Gluconolaconase
CFBP5473_RS12280	COG5001	Diguanylate cyclase
CFBP5473_RS12280	COG3300	MHYT domain
CFBP5473_RS12285	COG0784	Response regulator, receiver
CFBP5473_RS12285	COG5002	protein histidine kinase activity
CFBP5473_RS12285	COG2198	Histidine kinase
CFBP5473_RS12290	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFBP5473_RS12300	COG3685	Protein conserved in bacteria
CFBP5473_RS12310	COG1663	tetraacyldisaccharide 4'-kinase activity
CFBP5473_RS12320	COG1519	Transferase
CFBP5473_RS12330	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5473_RS12335	COG0312	modulator of DNA gyrase
CFBP5473_RS12340	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP5473_RS12345	COG0742	ribosomal rna small subunit methyltransferase
CFBP5473_RS12350	COG1187	pseudouridine synthase activity
CFBP5473_RS12355	COG0590	tRNA wobble adenosine to inosine editing
CFBP5473_RS12365	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFBP5473_RS12370	COG0196	riboflavin kinase activity
CFBP5473_RS12385	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFBP5473_RS12390	COG0459	protein refolding
CFBP5473_RS12400	COG2259	Doxx family
CFBP5473_RS12410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFBP5473_RS12415	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFBP5473_RS12420	COG0124	histidyl-tRNA synthetase
CFBP5473_RS12445	COG0583	DNA-binding transcription factor activity
CFBP5473_RS12450	COG2855	membrane
CFBP5473_RS12460	COG2818	Glycosylase
CFBP5473_RS12465	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5473_RS12470	COG0247	lactate metabolic process
CFBP5473_RS12475	COG0277	FAD linked oxidase domain protein
CFBP5473_RS12485	COG0277	FAD linked oxidase domain protein
CFBP5473_RS12490	COG0583	DNA-binding transcription factor activity
CFBP5473_RS12495	COG0438	transferase activity, transferring glycosyl groups
CFBP5473_RS12500	COG0561	phosphatase activity
CFBP5473_RS12510	COG0306	phosphate transporter
CFBP5473_RS12530	COG0583	DNA-binding transcription factor activity
CFBP5473_RS12540	COG0583	DNA-binding transcription factor activity
CFBP5473_RS12545	COG0412	Dienelactone hydrolase
CFBP5473_RS12565	COG0477	Major facilitator Superfamily
CFBP5473_RS12570	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CFBP5473_RS12575	COG0248	Ppx GppA phosphatase
CFBP5473_RS12585	COG2205	protein histidine kinase activity
CFBP5473_RS12595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP5473_RS12600	COG1177	transmembrane transport
CFBP5473_RS12605	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5473_RS12610	COG3842	ATPase activity
CFBP5473_RS12640	COG2081	HI0933 family
CFBP5473_RS12650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5473_RS12655	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFBP5473_RS12660	COG0363	glucosamine-6-phosphate deaminase activity
CFBP5473_RS12665	COG0129	dihydroxy-acid dehydratase activity
CFBP5473_RS12675	COG3842	ATPase activity
CFBP5473_RS12680	COG0366	Alpha amylase catalytic
CFBP5473_RS12685	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS12690	COG1175	transmembrane transport
CFBP5473_RS12695	COG1653	transport
CFBP5473_RS12700	COG1609	Transcriptional regulator
CFBP5473_RS12705	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFBP5473_RS12715	COG1815	bacterial-type flagellum-dependent cell motility
CFBP5473_RS12720	COG1558	bacterial-type flagellum-dependent cell motility
CFBP5473_RS12725	COG1677	Flagellar hook-basal body complex protein FliE
CFBP5473_RS12730	COG4786	Flagellar basal body rod
CFBP5473_RS12735	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CFBP5473_RS12740	COG1706	bacterial-type flagellum-dependent cell motility
CFBP5473_RS12750	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CFBP5473_RS12760	COG1338	Plays a role in the flagellum-specific transport system
CFBP5473_RS12790	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP5473_RS12800	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CFBP5473_RS12805	COG0424	maF-like protein
CFBP5473_RS12810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFBP5473_RS12820	COG5328	Belongs to the UPF0262 family
CFBP5473_RS12825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFBP5473_RS12835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFBP5473_RS12890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP5473_RS13005	COG4794	Type iii secretion
CFBP5473_RS13015	COG5443	negative regulation of bacterial-type flagellum assembly
CFBP5473_RS13020	COG5442	Flagellar protein FlaF
CFBP5473_RS13030	COG1256	bacterial-type flagellum assembly
CFBP5473_RS13035	COG1749	Flagellar hook protein flgE
CFBP5473_RS13060	COG1360	Flagellar Motor Protein
CFBP5473_RS13070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP5473_RS13075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP5473_RS13080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP5473_RS13085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP5473_RS13100	COG1157	protein secretion by the type III secretion system
CFBP5473_RS13105	COG4786	Flagellar basal body rod
CFBP5473_RS13110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CFBP5473_RS13115	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP5473_RS13120	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP5473_RS13125	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP5473_RS13130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP5473_RS13140	COG0436	Aminotransferase
CFBP5473_RS13145	COG1970	mechanosensitive ion channel activity
CFBP5473_RS13150	COG2198	Histidine kinase
CFBP5473_RS13150	COG2205	protein histidine kinase activity
CFBP5473_RS13150	COG0784	Response regulator, receiver
CFBP5473_RS13155	COG0840	transmembrane signaling receptor activity
CFBP5473_RS13155	COG2972	Histidine kinase
CFBP5473_RS13165	COG2771	luxR family
CFBP5473_RS13170	COG1766	The M ring may be actively involved in energy transduction
CFBP5473_RS13195	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CFBP5473_RS13200	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS13205	COG2201	protein-glutamate methylesterase activity
CFBP5473_RS13210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CFBP5473_RS13215	COG0643	Histidine kinase
CFBP5473_RS13215	COG2198	Histidine kinase
CFBP5473_RS13220	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS13230	COG0840	transmembrane signaling receptor activity
CFBP5473_RS13240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFBP5473_RS13240	COG2111	Na H antiporter
CFBP5473_RS13245	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP5473_RS13250	COG0651	ATP synthesis coupled electron transport
CFBP5473_RS13255	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP5473_RS13260	COG2212	antiporter activity
CFBP5473_RS13265	COG1320	monovalent cation:proton antiporter activity
CFBP5473_RS13290	COG2205	protein histidine kinase activity
CFBP5473_RS13295	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS13315	COG1215	transferase activity, transferring glycosyl groups
CFBP5473_RS13320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFBP5473_RS13330	COG3012	SEC-C Motif Domain Protein
CFBP5473_RS13335	COG4372	Transposase
CFBP5473_RS13340	COG3436	PFAM IS66 Orf2 family protein
CFBP5473_RS13360	COG0582	viral genome integration into host DNA
CFBP5473_RS13375	COG2963	transposase activity
CFBP5473_RS13380	COG3436	PFAM IS66 Orf2 family protein
CFBP5473_RS13385	COG4372	Transposase
CFBP5473_RS13450	COG1024	Enoyl-CoA hydratase
CFBP5473_RS13450	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP5473_RS13455	COG0183	Belongs to the thiolase family
CFBP5473_RS13460	COG1960	acyl-CoA dehydrogenase activity
CFBP5473_RS13470	COG0730	response to heat
CFBP5473_RS13495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CFBP5473_RS13505	COG1201	RNA secondary structure unwinding
CFBP5473_RS13515	COG0167	dihydroorotate dehydrogenase activity
CFBP5473_RS13550	COG1132	(ABC) transporter
CFBP5473_RS13630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP5473_RS13660	COG0582	viral genome integration into host DNA
CFBP5473_RS13670	COG0717	Belongs to the dCTP deaminase family
CFBP5473_RS13680	COG2967	ApaG domain
CFBP5473_RS13695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFBP5473_RS13700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFBP5473_RS13715	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS13720	COG0704	Plays a role in the regulation of phosphate uptake
CFBP5473_RS13725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFBP5473_RS13735	COG0573	inorganic phosphate transmembrane transporter activity
CFBP5473_RS13740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFBP5473_RS13745	COG5002	protein histidine kinase activity
CFBP5473_RS13750	COG2326	polyphosphate kinase activity
CFBP5473_RS13770	COG3177	Filamentation induced by cAMP protein fic
CFBP5473_RS13775	COG4952	isomerase
CFBP5473_RS13785	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS13785	COG3347	Dehydrogenase
CFBP5473_RS13790	COG1349	DNA-binding transcription factor activity
CFBP5473_RS13800	COG1129	ABC transporter
CFBP5473_RS13805	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS13810	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS13815	COG3254	rhamnose metabolic process
CFBP5473_RS13830	COG3806	Anti-sigma factor
CFBP5473_RS13835	COG1595	DNA-templated transcription, initiation
CFBP5473_RS13850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP5473_RS13875	COG4774	siderophore transport
CFBP5473_RS13885	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5473_RS13890	COG3842	ATPase activity
CFBP5473_RS13895	COG0318	PFAM AMP-dependent synthetase and ligase
CFBP5473_RS13900	COG0166	Belongs to the GPI family
CFBP5473_RS13910	COG2207	Transcriptional regulator
CFBP5473_RS13915	COG1823	symporter activity
CFBP5473_RS13935	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFBP5473_RS13940	COG0418	dihydroorotase activity
CFBP5473_RS13945	COG3938	Belongs to the proline racemase family
CFBP5473_RS13970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5473_RS13995	COG0840	transmembrane signaling receptor activity
CFBP5473_RS14000	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFBP5473_RS14005	COG0594	ribonuclease P activity
CFBP5473_RS14010	COG0706	membrane insertase activity
CFBP5473_RS14015	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CFBP5473_RS14025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFBP5473_RS14050	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP5473_RS14055	COG1957	nucleoside hydrolase
CFBP5473_RS14060	COG3415	Transposase
CFBP5473_RS14060	COG2801	Transposase and inactivated derivatives
CFBP5473_RS14075	COG2171	N-acyltransferase activity
CFBP5473_RS14080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP5473_RS14095	COG1393	Belongs to the ArsC family
CFBP5473_RS14100	COG0101	tRNA pseudouridine synthase activity
CFBP5473_RS14105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFBP5473_RS14110	COG0242	peptide deformylase activity
CFBP5473_RS14120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5473_RS14130	COG0494	nUDIX hydrolase
CFBP5473_RS14135	COG1349	DNA-binding transcription factor activity
CFBP5473_RS14140	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFBP5473_RS14145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFBP5473_RS14150	COG1396	sequence-specific DNA binding
CFBP5473_RS14155	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CFBP5473_RS14160	COG1253	flavin adenine dinucleotide binding
CFBP5473_RS14165	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFBP5473_RS14170	COG1702	phosphate starvation-inducible protein PhoH
CFBP5473_RS14175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP5473_RS14190	COG0456	acetyltransferase
CFBP5473_RS14190	COG0454	-acetyltransferase
CFBP5473_RS14200	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CFBP5473_RS14210	COG0180	Tryptophanyl-tRNA synthetase
CFBP5473_RS14215	COG0728	peptidoglycan biosynthetic process
CFBP5473_RS14220	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFBP5473_RS14225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFBP5473_RS14230	COG0583	DNA-binding transcription factor activity
CFBP5473_RS14245	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFBP5473_RS14250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP5473_RS14255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CFBP5473_RS14265	COG0776	regulation of translation
CFBP5473_RS14270	COG0616	signal peptide processing
CFBP5473_RS14280	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CFBP5473_RS14285	COG1137	ATPase activity
CFBP5473_RS14295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFBP5473_RS14300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP5473_RS14305	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFBP5473_RS14310	COG1420	regulation of RNA biosynthetic process
CFBP5473_RS14315	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFBP5473_RS14320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFBP5473_RS14325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP5473_RS14335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFBP5473_RS14340	COG2226	methyltransferase
CFBP5473_RS14345	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFBP5473_RS14350	COG1024	Enoyl-CoA hydratase
CFBP5473_RS14355	COG0268	Binds directly to 16S ribosomal RNA
CFBP5473_RS14360	COG3335	DDE superfamily endonuclease
CFBP5473_RS14385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFBP5473_RS14460	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS14475	COG0475	glutathione-regulated potassium exporter activity
CFBP5473_RS14485	COG4372	Transposase
CFBP5473_RS14495	COG2963	transposase activity
CFBP5473_RS14505	COG2207	Transcriptional regulator
CFBP5473_RS14520	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5473_RS14530	COG1802	Transcriptional regulator
CFBP5473_RS14535	COG0747	negative chemotaxis
CFBP5473_RS14540	COG0601	transmembrane transport
CFBP5473_RS14545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS14565	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS14585	COG5002	protein histidine kinase activity
CFBP5473_RS14595	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CFBP5473_RS14620	COG3920	Histidine kinase
CFBP5473_RS14625	COG0784	Response regulator, receiver
CFBP5473_RS14625	COG4191	Histidine kinase
CFBP5473_RS14640	COG1487	ribonuclease activity
CFBP5473_RS14645	COG4691	Plasmid stability protein
CFBP5473_RS14660	COG1780	Probably involved in ribonucleotide reductase function
CFBP5473_RS14665	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFBP5473_RS14675	COG1120	ATPase activity
CFBP5473_RS14680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5473_RS14685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5473_RS14700	COG3920	Histidine kinase
CFBP5473_RS14700	COG2202	Pas domain
CFBP5473_RS14705	COG0784	Response regulator, receiver
CFBP5473_RS14710	COG4191	Histidine kinase
CFBP5473_RS14710	COG0784	Response regulator, receiver
CFBP5473_RS14715	COG0784	Response regulator, receiver
CFBP5473_RS14715	COG4191	Histidine kinase
CFBP5473_RS14720	COG0628	permease
CFBP5473_RS14725	COG5001	Diguanylate cyclase
CFBP5473_RS14735	COG0840	transmembrane signaling receptor activity
CFBP5473_RS14745	COG1733	regulation of RNA biosynthetic process
CFBP5473_RS14755	COG3387	PFAM Glycoside hydrolase 15-related
CFBP5473_RS14760	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS14765	COG3386	PFAM SMP-30 Gluconolaconase
CFBP5473_RS14785	COG1595	DNA-templated transcription, initiation
CFBP5473_RS14820	COG3077	Addiction module antitoxin, RelB DinJ family
CFBP5473_RS14840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CFBP5473_RS14840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP5473_RS14870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5473_RS14875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFBP5473_RS14880	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CFBP5473_RS14885	COG2080	2 iron, 2 sulfur cluster binding
CFBP5473_RS14890	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFBP5473_RS14895	COG1309	transcriptional regulator
CFBP5473_RS14905	COG3842	ATPase activity
CFBP5473_RS14915	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5473_RS14945	COG4172	Belongs to the ABC transporter superfamily
CFBP5473_RS14950	COG1921	L-seryl-tRNASec selenium transferase activity
CFBP5473_RS14965	COG3964	amidohydrolase
CFBP5473_RS14975	COG0601	transmembrane transport
CFBP5473_RS14980	COG0747	negative chemotaxis
CFBP5473_RS14985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP5473_RS14985	COG3453	Protein conserved in bacteria
CFBP5473_RS14990	COG0515	serine threonine protein kinase
CFBP5473_RS14990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CFBP5473_RS15000	COG0747	negative chemotaxis
CFBP5473_RS15005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS15010	COG0601	transmembrane transport
CFBP5473_RS15025	COG4172	Belongs to the ABC transporter superfamily
CFBP5473_RS15030	COG1802	Transcriptional regulator
CFBP5473_RS15040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CFBP5473_RS15055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CFBP5473_RS15075	COG3842	ATPase activity
CFBP5473_RS15085	COG1175	transmembrane transport
CFBP5473_RS15100	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS15105	COG1609	Transcriptional regulator
CFBP5473_RS15120	COG0583	DNA-binding transcription factor activity
CFBP5473_RS15135	COG1177	transmembrane transport
CFBP5473_RS15140	COG3842	ATPase activity
CFBP5473_RS15145	COG2072	flavoprotein involved in K transport
CFBP5473_RS15180	COG2017	converts alpha-aldose to the beta-anomer
CFBP5473_RS15185	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5473_RS15190	COG4172	Belongs to the ABC transporter superfamily
CFBP5473_RS15195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS15200	COG0601	transmembrane transport
CFBP5473_RS15205	COG0747	negative chemotaxis
CFBP5473_RS15220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5473_RS15225	COG0514	ATP-dependent DNA helicase (RecQ)
CFBP5473_RS15235	COG0110	maltose O-acetyltransferase activity
CFBP5473_RS15255	COG3842	ATPase activity
CFBP5473_RS15265	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS15270	COG1175	transmembrane transport
CFBP5473_RS15285	COG2186	Transcriptional regulator
CFBP5473_RS15295	COG4172	Belongs to the ABC transporter superfamily
CFBP5473_RS15300	COG0405	Gamma-glutamyltransferase
CFBP5473_RS15305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS15310	COG0601	transmembrane transport
CFBP5473_RS15315	COG0747	negative chemotaxis
CFBP5473_RS15320	COG2188	Transcriptional regulator
CFBP5473_RS15325	COG0577	efflux transmembrane transporter activity
CFBP5473_RS15325	COG1136	(ABC) transporter
CFBP5473_RS15330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5473_RS15450	COG0515	serine threonine protein kinase
CFBP5473_RS15460	COG3300	MHYT domain
CFBP5473_RS15460	COG5001	Diguanylate cyclase
CFBP5473_RS15470	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP5473_RS15475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP5473_RS15480	COG4770	biotin carboxylase activity
CFBP5473_RS15490	COG0747	negative chemotaxis
CFBP5473_RS15500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS15515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5473_RS15520	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5473_RS15525	COG4172	Belongs to the ABC transporter superfamily
CFBP5473_RS15530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS15535	COG0601	transmembrane transport
CFBP5473_RS15540	COG4166	transmembrane transport
CFBP5473_RS15555	COG3842	ATPase activity
CFBP5473_RS15560	COG3842	ATPase activity
CFBP5473_RS15570	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS15585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS15590	COG4175	Glycine betaine
CFBP5473_RS15590	COG0517	IMP dehydrogenase activity
CFBP5473_RS15595	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5473_RS15610	COG0450	alkyl hydroperoxide reductase
CFBP5473_RS15615	COG0488	(ABC) transporter
CFBP5473_RS15620	COG3706	GGDEF domain
CFBP5473_RS15630	COG1120	ATPase activity
CFBP5473_RS15640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CFBP5473_RS15665	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP5473_RS15680	COG0297	glycogen (starch) synthase activity
CFBP5473_RS15690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP5473_RS15700	COG4529	Protein conserved in bacteria
CFBP5473_RS15720	COG0577	efflux transmembrane transporter activity
CFBP5473_RS15750	COG2197	response regulator
CFBP5473_RS15795	COG0129	dihydroxy-acid dehydratase activity
CFBP5473_RS15800	COG1879	ABC-type sugar transport system periplasmic component
CFBP5473_RS15805	COG1129	ABC transporter
CFBP5473_RS15810	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS15815	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS15820	COG2186	Transcriptional regulator
CFBP5473_RS15825	COG0587	DNA-directed DNA polymerase activity
CFBP5473_RS15840	COG3307	-O-antigen
CFBP5473_RS15845	COG1596	polysaccharide export
CFBP5473_RS15855	COG0693	protein deglycase activity
CFBP5473_RS15875	COG3485	protocatechuate 3,4-dioxygenase
CFBP5473_RS15880	COG3485	protocatechuate 3,4-dioxygenase
CFBP5473_RS15885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFBP5473_RS15895	COG0583	DNA-binding transcription factor activity
CFBP5473_RS15910	COG1414	Transcriptional regulator
CFBP5473_RS15920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFBP5473_RS15925	COG0183	Belongs to the thiolase family
CFBP5473_RS15940	COG5001	Diguanylate cyclase
CFBP5473_RS15945	COG0683	leucine binding
CFBP5473_RS15970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP5473_RS15985	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP5473_RS15990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CFBP5473_RS16025	COG1960	acyl-CoA dehydrogenase activity
CFBP5473_RS16040	COG1024	Enoyl-CoA hydratase
CFBP5473_RS16055	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CFBP5473_RS16055	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5473_RS16065	COG1940	carbohydrate kinase activity
CFBP5473_RS16070	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFBP5473_RS16075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP5473_RS16080	COG2188	Transcriptional regulator
CFBP5473_RS16090	COG1175	transmembrane transport
CFBP5473_RS16095	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS16105	COG3842	ATPase activity
CFBP5473_RS16120	COG0251	oxidation-reduction process
CFBP5473_RS16125	COG1737	Transcriptional regulator
CFBP5473_RS16130	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS16150	COG3142	Participates in the control of copper homeostasis
CFBP5473_RS16155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP5473_RS16175	COG2203	Gaf domain
CFBP5473_RS16175	COG3706	GGDEF domain
CFBP5473_RS16175	COG4251	negative regulation of phosphorylation
CFBP5473_RS16175	COG5001	Diguanylate cyclase
CFBP5473_RS16185	COG2897	thiosulfate sulfurtransferase activity
CFBP5473_RS16190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS16205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5473_RS16210	COG1126	abc transporter atp-binding protein
CFBP5473_RS16220	COG1473	amidohydrolase
CFBP5473_RS16225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS16230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS16240	COG1312	Catalyzes the dehydration of D-mannonate
CFBP5473_RS16250	COG3842	ATPase activity
CFBP5473_RS16255	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS16260	COG1175	transmembrane transport
CFBP5473_RS16265	COG1653	transport
CFBP5473_RS16270	COG2017	converts alpha-aldose to the beta-anomer
CFBP5473_RS16315	COG1116	anion transmembrane transporter activity
CFBP5473_RS16320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5473_RS16325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5473_RS16330	COG1464	Belongs to the NlpA lipoprotein family
CFBP5473_RS16340	COG2011	ABC-type metal ion transport system permease component
CFBP5473_RS16355	COG1737	Transcriptional regulator
CFBP5473_RS16360	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS16365	COG1129	ABC transporter
CFBP5473_RS16385	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS16390	COG1175	transmembrane transport
CFBP5473_RS16400	COG3842	ATPase activity
CFBP5473_RS16425	COG1879	ABC-type sugar transport system periplasmic component
CFBP5473_RS16430	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS16435	COG2376	Dihydroxyacetone kinase
CFBP5473_RS16445	COG2376	Dihydroxyacetone kinase
CFBP5473_RS16450	COG1461	Dihydroxyacetone kinase
CFBP5473_RS16465	COG0747	negative chemotaxis
CFBP5473_RS16485	COG4608	Belongs to the ABC transporter superfamily
CFBP5473_RS16490	COG0667	Aldo Keto reductase
CFBP5473_RS16500	COG0583	DNA-binding transcription factor activity
CFBP5473_RS16505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS16525	COG1473	amidohydrolase
CFBP5473_RS16530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS16545	COG0778	Nitroreductase
CFBP5473_RS16565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS16575	COG1116	anion transmembrane transporter activity
CFBP5473_RS16580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5473_RS16585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5473_RS16595	COG0747	negative chemotaxis
CFBP5473_RS16600	COG0601	transmembrane transport
CFBP5473_RS16610	COG0444	Belongs to the ABC transporter superfamily
CFBP5473_RS16625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5473_RS16630	COG1116	anion transmembrane transporter activity
CFBP5473_RS16635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS16640	COG2814	Major facilitator Superfamily
CFBP5473_RS16645	COG0667	Aldo Keto reductase
CFBP5473_RS16650	COG0583	DNA-binding transcription factor activity
CFBP5473_RS16685	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS16695	COG2182	Extracellular solute-binding protein
CFBP5473_RS16700	COG0626	cystathionine gamma-synthase activity
CFBP5473_RS16710	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5473_RS16715	COG3842	ATPase activity
CFBP5473_RS16725	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5473_RS16730	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5473_RS16740	COG0784	Response regulator, receiver
CFBP5473_RS16740	COG4191	Histidine kinase
CFBP5473_RS16770	COG3609	addiction module antidote protein, CC2985 family
CFBP5473_RS16860	COG2814	Major facilitator Superfamily
CFBP5473_RS16865	COG2233	PERMEase
CFBP5473_RS16870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5473_RS16875	COG5001	Diguanylate cyclase
CFBP5473_RS16895	COG4989	oxidoreductase activity
CFBP5473_RS16900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS16910	COG3842	ATPase activity
CFBP5473_RS16915	COG1653	transport
CFBP5473_RS16925	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS16930	COG1501	Belongs to the glycosyl hydrolase 31 family
CFBP5473_RS16940	COG0765	amino acid transport
CFBP5473_RS16955	COG2186	Transcriptional regulator
CFBP5473_RS16985	COG3712	iron ion homeostasis
CFBP5473_RS16990	COG4774	siderophore transport
CFBP5473_RS16995	COG2814	Major facilitator Superfamily
CFBP5473_RS17000	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS17035	COG0438	transferase activity, transferring glycosyl groups
CFBP5473_RS17050	COG0438	transferase activity, transferring glycosyl groups
CFBP5473_RS17065	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP5473_RS17065	COG0489	protein tyrosine kinase activity
CFBP5473_RS17095	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFBP5473_RS17100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFBP5473_RS17105	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CFBP5473_RS17110	COG2080	2 iron, 2 sulfur cluster binding
CFBP5473_RS17115	COG1802	Transcriptional regulator
CFBP5473_RS17125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP5473_RS17130	COG0765	amino acid transport
CFBP5473_RS17135	COG0765	amino acid transport
CFBP5473_RS17140	COG1126	abc transporter atp-binding protein
CFBP5473_RS17145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP5473_RS17160	COG3046	protein related to deoxyribodipyrimidine photolyase
CFBP5473_RS17165	COG2155	Conserved Protein
CFBP5473_RS17190	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS17200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP5473_RS17205	COG0747	negative chemotaxis
CFBP5473_RS17210	COG0601	transmembrane transport
CFBP5473_RS17215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS17220	COG0444	Belongs to the ABC transporter superfamily
CFBP5473_RS17225	COG4608	Belongs to the ABC transporter superfamily
CFBP5473_RS17230	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS17240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFBP5473_RS17255	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5473_RS17260	COG3842	ATPase activity
CFBP5473_RS17280	COG2072	flavoprotein involved in K transport
CFBP5473_RS17285	COG1120	ATPase activity
CFBP5473_RS17290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5473_RS17300	COG2226	methyltransferase
CFBP5473_RS17305	COG3842	ATPase activity
CFBP5473_RS17310	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS17320	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS17325	COG1175	transmembrane transport
CFBP5473_RS17335	COG1309	transcriptional regulator
CFBP5473_RS17340	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS17365	COG5002	protein histidine kinase activity
CFBP5473_RS17365	COG2198	Histidine kinase
CFBP5473_RS17365	COG0784	Response regulator, receiver
CFBP5473_RS17380	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5473_RS17390	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS17395	COG2094	Belongs to the DNA glycosylase MPG family
CFBP5473_RS17405	COG0602	queuosine metabolic process
CFBP5473_RS17410	COG0720	synthase
CFBP5473_RS17415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFBP5473_RS17420	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS17430	COG3842	ATPase activity
CFBP5473_RS17435	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS17440	COG1175	transmembrane transport
CFBP5473_RS17465	COG2198	Histidine kinase
CFBP5473_RS17465	COG0643	Histidine kinase
CFBP5473_RS17470	COG0835	chemotaxis
CFBP5473_RS17475	COG0840	transmembrane signaling receptor activity
CFBP5473_RS17485	COG0840	transmembrane signaling receptor activity
CFBP5473_RS17490	COG0840	transmembrane signaling receptor activity
CFBP5473_RS17495	COG0835	chemotaxis
CFBP5473_RS17500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CFBP5473_RS17505	COG2201	protein-glutamate methylesterase activity
CFBP5473_RS17510	COG1192	Involved in chromosome partitioning
CFBP5473_RS17520	COG0281	malic enzyme
CFBP5473_RS17520	COG0280	phosphate acetyltransferase
CFBP5473_RS17525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CFBP5473_RS17535	COG1879	ABC-type sugar transport system periplasmic component
CFBP5473_RS17540	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS17545	COG1129	ABC transporter
CFBP5473_RS17550	COG1609	Transcriptional regulator
CFBP5473_RS17565	COG1215	transferase activity, transferring glycosyl groups
CFBP5473_RS17570	COG2327	Polysaccharide pyruvyl transferase
CFBP5473_RS17575	COG0463	Glycosyl transferase, family 2
CFBP5473_RS17580	COG2244	polysaccharide biosynthetic process
CFBP5473_RS17585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP5473_RS17590	COG2273	Hydrolase Family 16
CFBP5473_RS17595	COG0438	transferase activity, transferring glycosyl groups
CFBP5473_RS17600	COG1215	transferase activity, transferring glycosyl groups
CFBP5473_RS17605	COG1215	transferase activity, transferring glycosyl groups
CFBP5473_RS17610	COG1215	transferase activity, transferring glycosyl groups
CFBP5473_RS17615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP5473_RS17620	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP5473_RS17620	COG0489	protein tyrosine kinase activity
CFBP5473_RS17625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP5473_RS17630	COG0784	Response regulator, receiver
CFBP5473_RS17630	COG4191	Histidine kinase
CFBP5473_RS17645	COG0564	pseudouridine synthase activity
CFBP5473_RS17650	COG0500	methyltransferase
CFBP5473_RS17660	COG2133	pyrroloquinoline quinone binding
CFBP5473_RS17675	COG2194	sulfuric ester hydrolase activity
CFBP5473_RS17680	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS17690	COG0477	Major facilitator Superfamily
CFBP5473_RS17700	COG0840	transmembrane signaling receptor activity
CFBP5473_RS17710	COG4774	siderophore transport
CFBP5473_RS17720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5473_RS17725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5473_RS17730	COG1120	ATPase activity
CFBP5473_RS17740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5473_RS17750	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CFBP5473_RS17755	COG2894	cell division
CFBP5473_RS17760	COG0850	regulation of cytokinetic process
CFBP5473_RS17820	COG2211	Major facilitator Superfamily
CFBP5473_RS17830	COG2137	regulation of response to DNA damage stimulus
CFBP5473_RS17860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFBP5473_RS17860	COG0425	Belongs to the sulfur carrier protein TusA family
CFBP5473_RS17875	COG0189	ligase activity
CFBP5473_RS17890	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFBP5473_RS17890	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFBP5473_RS17900	COG2890	protein-(glutamine-N5) methyltransferase activity
CFBP5473_RS17905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFBP5473_RS17915	COG0527	aspartate kinase activity
CFBP5473_RS17930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP5473_RS17940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP5473_RS17945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFBP5473_RS17950	COG1040	competence protein
CFBP5473_RS17955	COG2226	methyltransferase
CFBP5473_RS17970	COG0494	nUDIX hydrolase
CFBP5473_RS17980	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFBP5473_RS17985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFBP5473_RS17990	COG0653	protein targeting
CFBP5473_RS17995	COG1653	transport
CFBP5473_RS18000	COG1175	transmembrane transport
CFBP5473_RS18005	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS18010	COG3842	ATPase activity
CFBP5473_RS18030	COG0022	dehydrogenase e1 component
CFBP5473_RS18040	COG1960	acyl-CoA dehydrogenase activity
CFBP5473_RS18055	COG0438	transferase activity, transferring glycosyl groups
CFBP5473_RS18090	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP5473_RS18090	COG0489	protein tyrosine kinase activity
CFBP5473_RS18095	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS18120	COG0165	Argininosuccinate lyase
CFBP5473_RS18125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFBP5473_RS18130	COG0625	glutathione transferase activity
CFBP5473_RS18135	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP5473_RS18145	COG2086	electron transfer activity
CFBP5473_RS18150	COG0705	Rhomboid family
CFBP5473_RS18165	COG0300	oxidoreductase activity
CFBP5473_RS18175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP5473_RS18205	COG0825	malonyl-CoA metabolic process
CFBP5473_RS18210	COG4974	Belongs to the 'phage' integrase family
CFBP5473_RS18220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFBP5473_RS18225	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFBP5473_RS18270	COG2884	Cell division ATP-binding protein ftsE
CFBP5473_RS18285	COG0542	response to heat
CFBP5473_RS18300	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP5473_RS18305	COG2207	Transcriptional regulator
CFBP5473_RS18315	COG0840	transmembrane signaling receptor activity
CFBP5473_RS18315	COG2972	Histidine kinase
CFBP5473_RS18325	COG1396	sequence-specific DNA binding
CFBP5473_RS18330	COG3842	ATPase activity
CFBP5473_RS18335	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS18340	COG1175	transmembrane transport
CFBP5473_RS18345	COG1653	transport
CFBP5473_RS18350	COG0792	nuclease activity
CFBP5473_RS18355	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFBP5473_RS18365	COG3963	phosphatidate phosphatase activity
CFBP5473_RS18375	COG0284	orotidine-5'-phosphate decarboxylase activity
CFBP5473_RS18395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFBP5473_RS18405	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CFBP5473_RS18410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFBP5473_RS18410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFBP5473_RS18450	COG0519	Catalyzes the synthesis of GMP from XMP
CFBP5473_RS18450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFBP5473_RS18465	COG1393	Belongs to the ArsC family
CFBP5473_RS18475	COG2309	aminopeptidase activity
CFBP5473_RS18485	COG0372	Belongs to the citrate synthase family
CFBP5473_RS18490	COG0697	spore germination
CFBP5473_RS18495	COG1846	Transcriptional regulator
CFBP5473_RS18500	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5473_RS18505	COG1570	exodeoxyribonuclease VII activity
CFBP5473_RS18535	COG0667	Aldo Keto reductase
CFBP5473_RS18550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP5473_RS18560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5473_RS18610	COG2814	Major facilitator Superfamily
CFBP5473_RS18650	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP5473_RS18690	COG0739	heme binding
CFBP5473_RS18690	COG1196	nuclear chromosome segregation
CFBP5473_RS18690	COG0741	lytic transglycosylase activity
CFBP5473_RS18695	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP5473_RS18700	COG4208	sulfate ABC transporter
CFBP5473_RS18710	COG4150	thiosulfate binding
CFBP5473_RS18730	COG0019	diaminopimelate decarboxylase activity
CFBP5473_RS18745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFBP5473_RS18765	COG0784	Response regulator, receiver
CFBP5473_RS18780	COG1522	sequence-specific DNA binding
CFBP5473_RS18790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP5473_RS18800	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5473_RS18805	COG3842	ATPase activity
CFBP5473_RS18820	COG0583	DNA-binding transcription factor activity
CFBP5473_RS18825	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5473_RS18830	COG0583	DNA-binding transcription factor activity
CFBP5473_RS18840	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFBP5473_RS18845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5473_RS18860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5473_RS18870	COG4993	Dehydrogenase
CFBP5473_RS18875	COG1253	flavin adenine dinucleotide binding
CFBP5473_RS18880	COG0252	asparaginase activity
CFBP5473_RS18890	COG1027	Aspartate ammonia-lyase
CFBP5473_RS18895	COG2186	Transcriptional regulator
CFBP5473_RS18900	COG3707	response regulator
CFBP5473_RS18905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5473_RS18910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5473_RS18915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5473_RS18920	COG1116	anion transmembrane transporter activity
CFBP5473_RS18925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFBP5473_RS18935	COG0243	molybdopterin cofactor binding
CFBP5473_RS18940	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS18950	COG4221	oxidoreductase activity
CFBP5473_RS18960	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP5473_RS18970	COG0539	negative regulation of cytoplasmic translation
CFBP5473_RS18975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CFBP5473_RS18990	COG0288	reversible hydration of carbon dioxide
CFBP5473_RS19000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFBP5473_RS19015	COG0246	Mannitol dehydrogenase
CFBP5473_RS19020	COG1312	Catalyzes the dehydration of D-mannonate
CFBP5473_RS19025	COG1063	alcohol dehydrogenase
CFBP5473_RS19030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5473_RS19040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5473_RS19065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP5473_RS19070	COG2267	carboxylic ester hydrolase activity
CFBP5473_RS19075	COG0251	oxidation-reduction process
CFBP5473_RS19080	COG1335	isochorismatase
CFBP5473_RS19085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS19090	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS19095	COG3181	Tripartite tricarboxylate transporter family receptor
CFBP5473_RS19100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP5473_RS19100	COG0072	phenylalanine-tRNA ligase activity
CFBP5473_RS19115	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFBP5473_RS19125	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFBP5473_RS19130	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFBP5473_RS19135	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFBP5473_RS19150	COG1309	transcriptional regulator
CFBP5473_RS19155	COG0251	oxidation-reduction process
CFBP5473_RS19180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP5473_RS19190	COG1192	Involved in chromosome partitioning
CFBP5473_RS19195	COG1475	DNA binding
CFBP5473_RS19200	COG1414	Transcriptional regulator
CFBP5473_RS19210	COG0189	ligase activity
CFBP5473_RS19215	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP5473_RS19230	COG3304	Inner membrane component domain
CFBP5473_RS19280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFBP5473_RS19280	COG0784	Response regulator, receiver
CFBP5473_RS19285	COG0606	chelatase, subunit chli
CFBP5473_RS19305	COG0583	DNA-binding transcription factor activity
CFBP5473_RS19310	COG4953	penicillin-binding protein 1C
CFBP5473_RS19315	COG2373	Large extracellular alpha-helical protein
CFBP5473_RS19320	COG1473	amidohydrolase
CFBP5473_RS19330	COG0765	amino acid transport
CFBP5473_RS19350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP5473_RS19360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5473_RS19365	COG1116	anion transmembrane transporter activity
CFBP5473_RS19380	COG0583	DNA-binding transcription factor activity
CFBP5473_RS19395	COG0784	Response regulator, receiver
CFBP5473_RS19395	COG4191	Histidine kinase
CFBP5473_RS19410	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS19415	COG2835	tetraacyldisaccharide 4'-kinase activity
CFBP5473_RS19445	COG0477	Major facilitator Superfamily
CFBP5473_RS19460	COG1960	acyl-CoA dehydrogenase activity
CFBP5473_RS19465	COG0583	DNA-binding transcription factor activity
CFBP5473_RS19475	COG0747	negative chemotaxis
CFBP5473_RS19480	COG0601	transmembrane transport
CFBP5473_RS19485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS19490	COG0444	Belongs to the ABC transporter superfamily
CFBP5473_RS19495	COG4608	Belongs to the ABC transporter superfamily
CFBP5473_RS19510	COG0747	negative chemotaxis
CFBP5473_RS19525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS19530	COG2390	Transcriptional regulator
CFBP5473_RS19540	COG1175	transmembrane transport
CFBP5473_RS19545	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS19565	COG1069	ribulokinase activity
CFBP5473_RS19575	COG0436	Aminotransferase
CFBP5473_RS19580	COG2942	2-epimerase
CFBP5473_RS19590	COG1215	transferase activity, transferring glycosyl groups
CFBP5473_RS19610	COG1959	2 iron, 2 sulfur cluster binding
CFBP5473_RS19615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP5473_RS19620	COG0183	Belongs to the thiolase family
CFBP5473_RS19635	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5473_RS19645	COG3842	ATPase activity
CFBP5473_RS19655	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP5473_RS19660	COG1473	amidohydrolase
CFBP5473_RS19665	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CFBP5473_RS19670	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP5473_RS19680	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP5473_RS19700	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS19705	COG0243	molybdopterin cofactor binding
CFBP5473_RS19725	COG2226	methyltransferase
CFBP5473_RS19760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP5473_RS19765	COG2010	Cytochrome c
CFBP5473_RS19765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFBP5473_RS19800	COG4214	carbohydrate transport
CFBP5473_RS19810	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS19830	COG3718	enzyme involved in inositol metabolism
CFBP5473_RS19840	COG3962	Belongs to the TPP enzyme family
CFBP5473_RS19850	COG1737	Transcriptional regulator
CFBP5473_RS19855	COG4770	biotin carboxylase activity
CFBP5473_RS19860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP5473_RS19875	COG1301	dicarboxylic acid transport
CFBP5473_RS19880	COG4191	Histidine kinase
CFBP5473_RS19885	COG2204	response regulator
CFBP5473_RS19895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5473_RS19900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP5473_RS19905	COG1522	sequence-specific DNA binding
CFBP5473_RS19910	COG0351	phosphomethylpyrimidine kinase
CFBP5473_RS19915	COG0352	thiamine-phosphate diphosphorylase activity
CFBP5473_RS19920	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CFBP5473_RS19935	COG3395	kinase activity
CFBP5473_RS19940	COG1454	alcohol dehydrogenase
CFBP5473_RS19945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5473_RS19950	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP5473_RS19960	COG0747	negative chemotaxis
CFBP5473_RS19965	COG0601	transmembrane transport
CFBP5473_RS19970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS19985	COG0006	proline dipeptidase activity
CFBP5473_RS19995	COG0392	lysyltransferase activity
CFBP5473_RS19995	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFBP5473_RS20025	COG1473	amidohydrolase
CFBP5473_RS20030	COG1686	Belongs to the peptidase S11 family
CFBP5473_RS20035	COG0523	cobalamin synthesis protein
CFBP5473_RS20040	COG0287	Prephenate dehydrogenase
CFBP5473_RS20045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP5473_RS20050	COG2226	methyltransferase
CFBP5473_RS20055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP5473_RS20065	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS20070	COG1129	ABC transporter
CFBP5473_RS20080	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS20085	COG3959	Transketolase, thiamine diphosphate binding domain
CFBP5473_RS20090	COG3958	Transketolase
CFBP5473_RS20095	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP5473_RS20100	COG2390	Transcriptional regulator
CFBP5473_RS20110	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CFBP5473_RS20120	COG3119	arylsulfatase activity
CFBP5473_RS20130	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFBP5473_RS20135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFBP5473_RS20150	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP5473_RS20155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP5473_RS20160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5473_RS20170	COG1126	abc transporter atp-binding protein
CFBP5473_RS20175	COG0765	amino acid transport
CFBP5473_RS20180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5473_RS20185	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CFBP5473_RS20205	COG4702	Belongs to the UPF0303 family
CFBP5473_RS20230	COG0784	Response regulator, receiver
CFBP5473_RS20230	COG4191	Histidine kinase
CFBP5473_RS20240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP5473_RS20245	COG1278	Cold shock
CFBP5473_RS20260	COG0598	Magnesium transport protein CorA
CFBP5473_RS20270	COG0183	Belongs to the thiolase family
CFBP5473_RS20275	COG3396	Phenylacetate-CoA oxygenase
CFBP5473_RS20280	COG3460	Phenylacetate-CoA oxygenase
CFBP5473_RS20285	COG3396	Phenylacetate-CoA oxygenase
CFBP5473_RS20290	COG2151	metal-sulfur cluster biosynthetic enzyme
CFBP5473_RS20295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFBP5473_RS20300	COG2030	dehydratase
CFBP5473_RS20300	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5473_RS20310	COG1309	transcriptional regulator
CFBP5473_RS20320	COG2050	protein possibly involved in aromatic compounds catabolism
CFBP5473_RS20325	COG1024	Enoyl-CoA hydratase
CFBP5473_RS20335	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS20365	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5473_RS20395	COG3210	domain, Protein
CFBP5473_RS20400	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS20405	COG2205	protein histidine kinase activity
CFBP5473_RS20410	COG0406	alpha-ribazole phosphatase activity
CFBP5473_RS20415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFBP5473_RS20435	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS20445	COG3842	ATPase activity
CFBP5473_RS20450	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5473_RS20465	COG0010	Belongs to the arginase family
CFBP5473_RS20470	COG2423	ornithine cyclodeaminase activity
CFBP5473_RS20475	COG0697	spore germination
CFBP5473_RS20480	COG2217	Heavy metal translocating P-type atpase
CFBP5473_RS20490	COG0314	molybdopterin synthase activity
CFBP5473_RS20500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFBP5473_RS20505	COG0322	excinuclease ABC activity
CFBP5473_RS20510	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS20525	COG0625	glutathione transferase activity
CFBP5473_RS20540	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CFBP5473_RS20545	COG0243	molybdopterin cofactor binding
CFBP5473_RS20550	COG0494	nUDIX hydrolase
CFBP5473_RS20565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFBP5473_RS20570	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFBP5473_RS20575	COG0628	permease
CFBP5473_RS20585	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CFBP5473_RS20590	COG0248	Ppx GppA phosphatase
CFBP5473_RS20595	COG1285	pathogenesis
CFBP5473_RS20605	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CFBP5473_RS20610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFBP5473_RS20615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFBP5473_RS20625	COG0659	secondary active sulfate transmembrane transporter activity
CFBP5473_RS20635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP5473_RS20650	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CFBP5473_RS20660	COG0113	porphobilinogen synthase activity
CFBP5473_RS20680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFBP5473_RS20685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFBP5473_RS20690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP5473_RS20690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP5473_RS20700	COG1280	lysine exporter protein (LysE YggA)
CFBP5473_RS20705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFBP5473_RS20710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFBP5473_RS20715	COG2814	Major facilitator Superfamily
CFBP5473_RS20720	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CFBP5473_RS20730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5473_RS20745	COG1175	transmembrane transport
CFBP5473_RS20750	COG3833	ABC-type maltose transport systems, permease component
CFBP5473_RS20755	COG3842	ATPase activity
CFBP5473_RS20760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5473_RS20765	COG5001	Diguanylate cyclase
CFBP5473_RS20765	COG3300	MHYT domain
CFBP5473_RS20775	COG3257	ureidoglycine aminohydrolase activity
CFBP5473_RS20785	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CFBP5473_RS20785	COG2273	Hydrolase Family 16
CFBP5473_RS20800	COG2223	nitrite transmembrane transporter activity
CFBP5473_RS20805	COG0025	NhaP-type Na H and K H
CFBP5473_RS20815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFBP5473_RS20825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5473_RS20830	COG0657	acetylesterase activity
CFBP5473_RS20835	COG0583	DNA-binding transcription factor activity
CFBP5473_RS20840	COG1063	alcohol dehydrogenase
CFBP5473_RS20850	COG3708	Transcriptional regulator
CFBP5473_RS20850	COG2207	Transcriptional regulator
CFBP5473_RS20855	COG1879	ABC-type sugar transport system periplasmic component
CFBP5473_RS20865	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS20885	COG0789	Transcriptional regulator
CFBP5473_RS20890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFBP5473_RS20910	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS20915	COG1175	transmembrane transport
CFBP5473_RS20920	COG1653	transport
CFBP5473_RS20985	COG0583	DNA-binding transcription factor activity
CFBP5473_RS20990	COG0667	Aldo Keto reductase
CFBP5473_RS20995	COG2814	Major facilitator Superfamily
CFBP5473_RS21000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS21005	COG1116	anion transmembrane transporter activity
CFBP5473_RS21010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5473_RS21025	COG0444	Belongs to the ABC transporter superfamily
CFBP5473_RS21035	COG0601	transmembrane transport
CFBP5473_RS21040	COG0747	negative chemotaxis
CFBP5473_RS21075	COG1192	Involved in chromosome partitioning
CFBP5473_RS21080	COG1475	DNA binding
CFBP5473_RS21085	COG0640	Transcriptional regulator
CFBP5473_RS21090	COG1686	Belongs to the peptidase S11 family
CFBP5473_RS21105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5473_RS21110	COG2828	Protein conserved in bacteria
CFBP5473_RS21115	COG0583	DNA-binding transcription factor activity
CFBP5473_RS21185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP5473_RS21190	COG4644	lycopene metabolic process
CFBP5473_RS21225	COG4372	Transposase
CFBP5473_RS21230	COG3436	PFAM IS66 Orf2 family protein
CFBP5473_RS21235	COG2963	transposase activity
CFBP5473_RS21245	COG3209	COG3209 Rhs family protein
CFBP5473_RS21355	COG4944	Protein of unknown function (DUF1109)
CFBP5473_RS21370	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CFBP5473_RS21375	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFBP5473_RS21400	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CFBP5473_RS21410	COG3436	PFAM IS66 Orf2 family protein
CFBP5473_RS21415	COG4372	Transposase
CFBP5473_RS21420	COG3012	SEC-C Motif Domain Protein
CFBP5473_RS21425	COG0840	transmembrane signaling receptor activity
CFBP5473_RS21440	COG3177	Filamentation induced by cAMP protein fic
CFBP5473_RS21470	COG0784	Response regulator, receiver
CFBP5473_RS21475	COG3920	Histidine kinase
CFBP5473_RS21485	COG0784	Response regulator, receiver
CFBP5473_RS21485	COG4191	Histidine kinase
CFBP5473_RS21500	COG2202	Pas domain
CFBP5473_RS21500	COG3920	Histidine kinase
CFBP5473_RS21510	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFBP5473_RS21530	COG0385	Bile acid
CFBP5473_RS21535	COG3920	Histidine kinase
CFBP5473_RS21540	COG0784	Response regulator, receiver
CFBP5473_RS21540	COG4191	Histidine kinase
CFBP5473_RS21580	COG0587	DNA-directed DNA polymerase activity
CFBP5473_RS21590	COG3850	Histidine kinase
CFBP5473_RS21590	COG5002	protein histidine kinase activity
CFBP5473_RS21595	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS21610	COG2207	Transcriptional regulator
CFBP5473_RS21630	COG1278	Cold shock
CFBP5473_RS21645	COG0511	ligase activity, forming carbon-carbon bonds
CFBP5473_RS21650	COG0439	Biotin carboxylase
CFBP5473_RS21665	COG1984	allophanate hydrolase subunit 2
CFBP5473_RS21670	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP5473_RS21675	COG0436	Aminotransferase
CFBP5473_RS21685	COG4221	oxidoreductase activity
CFBP5473_RS21690	COG0765	amino acid transport
CFBP5473_RS21695	COG0765	amino acid transport
CFBP5473_RS21700	COG1126	abc transporter atp-binding protein
CFBP5473_RS21705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5473_RS21710	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP5473_RS21715	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS21720	COG3265	gluconokinase activity
CFBP5473_RS21725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5473_RS21730	COG1063	alcohol dehydrogenase
CFBP5473_RS21735	COG0583	DNA-binding transcription factor activity
CFBP5473_RS21740	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS21745	COG3959	Transketolase, thiamine diphosphate binding domain
CFBP5473_RS21750	COG3958	Transketolase
CFBP5473_RS21755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5473_RS21760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5473_RS21765	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5473_RS21770	COG1129	ABC transporter
CFBP5473_RS21775	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS21780	COG1879	ABC-type sugar transport system periplasmic component
CFBP5473_RS21785	COG3618	amidohydrolase
CFBP5473_RS21795	COG1609	Transcriptional regulator
CFBP5473_RS21805	COG1129	ABC transporter
CFBP5473_RS21810	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS21820	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5473_RS21825	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS21840	COG3962	Belongs to the TPP enzyme family
CFBP5473_RS21850	COG3718	enzyme involved in inositol metabolism
CFBP5473_RS21865	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS21870	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS21880	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS21885	COG1609	Transcriptional regulator
CFBP5473_RS21895	COG0840	transmembrane signaling receptor activity
CFBP5473_RS21915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5473_RS21925	COG2814	Major facilitator Superfamily
CFBP5473_RS21930	COG2801	Transposase and inactivated derivatives
CFBP5473_RS21970	COG0601	transmembrane transport
CFBP5473_RS21975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS21985	COG2843	Capsule synthesis protein
CFBP5473_RS21990	COG0154	amidase activity
CFBP5473_RS22000	COG5489	Protein of unknown function (DUF736)
CFBP5473_RS22010	COG3831	ATPase activity
CFBP5473_RS22015	COG3505	Type IV secretory pathway VirD4
CFBP5473_RS22030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP5473_RS22035	COG4959	Type IV secretory pathway protease TraF
CFBP5473_RS22040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP5473_RS22060	COG1476	TRANSCRIPTIONal
CFBP5473_RS22075	COG2948	multi-organism process
CFBP5473_RS22085	COG3504	Conjugal transfer protein
CFBP5473_RS22090	COG3701	Conjugal transfer protein
CFBP5473_RS22095	COG3846	protein secretion by the type IV secretion system
CFBP5473_RS22105	COG5314	conjugation
CFBP5473_RS22110	COG3451	type IV secretory pathway VirB4
CFBP5473_RS22115	COG5268	conjugation
CFBP5473_RS22120	COG3838	Conjugal transfer protein Trbc
CFBP5473_RS22125	COG4962	Type ii secretion system protein e
CFBP5473_RS22170	COG1902	pentaerythritol trinitrate reductase activity
CFBP5473_RS22180	COG0583	DNA-binding transcription factor activity
CFBP5473_RS22195	COG0583	DNA-binding transcription factor activity
CFBP5473_RS22215	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS22240	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP5473_RS22270	COG0210	DNA helicase
CFBP5473_RS22285	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5473_RS22290	COG0584	glycerophosphoryl diester phosphodiesterase
CFBP5473_RS22300	COG4149	molybdate abc transporter
CFBP5473_RS22305	COG3842	ATPase activity
CFBP5473_RS22330	COG0753	catalase activity
CFBP5473_RS22345	COG0673	inositol 2-dehydrogenase activity
CFBP5473_RS22350	COG0438	transferase activity, transferring glycosyl groups
CFBP5473_RS22360	COG2205	protein histidine kinase activity
CFBP5473_RS22370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFBP5473_RS22380	COG2076	Multidrug Resistance protein
CFBP5473_RS22395	COG2076	Multidrug Resistance protein
CFBP5473_RS22405	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5473_RS22415	COG2186	Transcriptional regulator
CFBP5473_RS22425	COG0444	Belongs to the ABC transporter superfamily
CFBP5473_RS22430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS22435	COG0601	transmembrane transport
CFBP5473_RS22440	COG0747	negative chemotaxis
CFBP5473_RS22445	COG3300	MHYT domain
CFBP5473_RS22445	COG5001	Diguanylate cyclase
CFBP5473_RS22450	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CFBP5473_RS22480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS22485	COG4172	Belongs to the ABC transporter superfamily
CFBP5473_RS22490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS22500	COG0431	NADPH-dependent FMN reductase
CFBP5473_RS22505	COG0306	phosphate transporter
CFBP5473_RS22510	COG1392	Phosphate transport regulator
CFBP5473_RS22520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFBP5473_RS22540	COG0583	DNA-binding transcription factor activity
CFBP5473_RS22545	COG0667	Aldo Keto reductase
CFBP5473_RS22550	COG1396	sequence-specific DNA binding
CFBP5473_RS22565	COG2030	dehydratase
CFBP5473_RS22575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP5473_RS22580	COG1960	acyl-CoA dehydrogenase activity
CFBP5473_RS22585	COG0583	DNA-binding transcription factor activity
CFBP5473_RS22595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5473_RS22615	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFBP5473_RS22630	COG3842	ATPase activity
CFBP5473_RS22635	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS22640	COG1175	transmembrane transport
CFBP5473_RS22660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5473_RS22665	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS22670	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CFBP5473_RS22690	COG2972	Histidine kinase
CFBP5473_RS22690	COG0840	transmembrane signaling receptor activity
CFBP5473_RS22695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFBP5473_RS22705	COG1802	Transcriptional regulator
CFBP5473_RS22710	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS22720	COG3842	ATPase activity
CFBP5473_RS22725	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5473_RS22730	COG1177	transmembrane transport
CFBP5473_RS22735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP5473_RS22740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CFBP5473_RS22745	COG2273	Hydrolase Family 16
CFBP5473_RS22750	COG0438	transferase activity, transferring glycosyl groups
CFBP5473_RS22755	COG1215	transferase activity, transferring glycosyl groups
CFBP5473_RS22760	COG1215	transferase activity, transferring glycosyl groups
CFBP5473_RS22765	COG1215	transferase activity, transferring glycosyl groups
CFBP5473_RS22775	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP5473_RS22775	COG0489	protein tyrosine kinase activity
CFBP5473_RS22805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFBP5473_RS22810	COG2755	lipolytic protein G-D-S-L family
CFBP5473_RS22810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP5473_RS22820	COG2244	polysaccharide biosynthetic process
CFBP5473_RS22840	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5473_RS22845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5473_RS22870	COG0840	transmembrane signaling receptor activity
CFBP5473_RS22875	COG4178	(ABC) transporter
CFBP5473_RS22885	COG1959	2 iron, 2 sulfur cluster binding
CFBP5473_RS22885	COG1295	ribonuclease BN
CFBP5473_RS22890	COG2200	EAL domain
CFBP5473_RS22900	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5473_RS22905	COG0572	uridine kinase
CFBP5473_RS22915	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS22920	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS22925	COG1129	ABC transporter
CFBP5473_RS22940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS22955	COG1192	Involved in chromosome partitioning
CFBP5473_RS22960	COG1475	DNA binding
CFBP5473_RS22965	COG0640	Transcriptional regulator
CFBP5473_RS22995	COG1484	DNA-dependent DNA replication
CFBP5473_RS23010	COG0653	protein targeting
CFBP5473_RS23035	COG3547	Transposase (IS116 IS110 IS902 family)
CFBP5473_RS23070	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS23180	COG0747	negative chemotaxis
CFBP5473_RS23190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5473_RS23195	COG4172	Belongs to the ABC transporter superfamily
CFBP5473_RS23245	COG1475	DNA binding
CFBP5473_RS23290	COG1064	alcohol dehydrogenase
CFBP5473_RS23320	COG1733	regulation of RNA biosynthetic process
CFBP5473_RS23340	COG5489	Protein of unknown function (DUF736)
CFBP5473_RS23430	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5473_RS23435	COG0584	glycerophosphoryl diester phosphodiesterase
CFBP5473_RS23445	COG1177	transmembrane transport
CFBP5473_RS23450	COG1175	transmembrane transport
CFBP5473_RS23455	COG3842	ATPase activity
CFBP5473_RS23460	COG1940	carbohydrate kinase activity
CFBP5473_RS23465	COG3012	SEC-C Motif Domain Protein
CFBP5473_RS23470	COG4372	Transposase
CFBP5473_RS23475	COG3436	PFAM IS66 Orf2 family protein
CFBP5473_RS23500	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CFBP5473_RS23540	COG0436	Aminotransferase
CFBP5473_RS23600	COG3012	SEC-C Motif Domain Protein
CFBP5473_RS23660	COG3335	DDE superfamily endonuclease
CFBP5473_RS23720	COG0745	RESPONSE REGULATOR receiver
CFBP5473_RS23730	COG1192	Involved in chromosome partitioning
CFBP5473_RS23740	COG3843	relaxase mobilization nuclease domain protein
CFBP5473_RS23750	COG3505	Type IV secretory pathway VirD4
CFBP5473_RS23805	COG3436	PFAM IS66 Orf2 family protein
CFBP5473_RS23810	COG2963	transposase activity
CFBP5473_RS23830	COG4372	Transposase
CFBP5473_RS23835	COG3436	PFAM IS66 Orf2 family protein
CFBP5473_RS23840	COG2963	transposase activity
CFBP5473_RS23865	COG1231	oxidoreductase activity
CFBP5473_RS23885	COG2222	sugar isomerase
CFBP5473_RS23895	COG0006	proline dipeptidase activity
CFBP5473_RS23980	COG1522	sequence-specific DNA binding
CFBP5473_RS23985	COG0460	homoserine dehydrogenase
CFBP5473_RS23995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFBP5473_RS24005	COG2040	homocysteine
CFBP5473_RS24025	COG3842	ATPase activity
CFBP5473_RS24030	COG0006	proline dipeptidase activity
CFBP5473_RS24035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5473_RS24050	COG0765	amino acid transport
CFBP5473_RS24055	COG0765	amino acid transport
CFBP5473_RS24060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5473_RS24075	COG2826	transposase and inactivated derivatives, IS30 family
CFBP5473_RS24090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5473_RS24110	COG1733	regulation of RNA biosynthetic process
CFBP5473_RS24140	COG0604	alcohol dehydrogenase
CFBP5473_RS24140	COG3321	synthase
CFBP5473_RS24140	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS24150	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5473_RS24190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5473_RS24215	COG4584	PFAM Integrase catalytic
CFBP5473_RS24215	COG2390	Transcriptional regulator
CFBP5473_RS24220	COG1484	DNA-dependent DNA replication
CFBP5473_RS24225	COG1733	regulation of RNA biosynthetic process
CFBP5473_RS24350	COG1609	Transcriptional regulator
CFBP5473_RS24370	COG3845	ABC transporter
CFBP5473_RS24375	COG4603	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS24380	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS24405	COG2963	transposase activity
CFBP5473_RS24410	COG3436	PFAM IS66 Orf2 family protein
CFBP5473_RS24415	COG4372	Transposase
CFBP5473_RS24430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5473_RS24435	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CFBP5473_RS24445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5473_RS24455	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5473_RS24465	COG3284	Transcriptional regulator
CFBP5473_RS24470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP5473_RS24480	COG2223	nitrite transmembrane transporter activity
CFBP5473_RS24485	COG1760	l-serine dehydratase
CFBP5473_RS24500	COG3842	ATPase activity
CFBP5473_RS24505	COG3833	ABC-type maltose transport systems, permease component
CFBP5473_RS24525	COG3547	Transposase (IS116 IS110 IS902 family)
CFBP5473_RS24555	COG0823	Involved in the tonB-independent uptake of proteins
CFBP5473_RS24570	COG3842	ATPase activity
CFBP5473_RS24575	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS24580	COG1175	transmembrane transport
CFBP5473_RS24585	COG1653	transport
CFBP5473_RS24590	COG1609	Transcriptional regulator
CFBP5473_RS24610	COG3842	ATPase activity
CFBP5473_RS24615	COG0656	L-ascorbic acid biosynthetic process
CFBP5473_RS24620	COG0395	ABC-type sugar transport system, permease component
CFBP5473_RS24635	COG1312	Catalyzes the dehydration of D-mannonate
CFBP5473_RS24640	COG1414	Transcriptional regulator
CFBP5473_RS24645	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5473_RS24655	COG4702	Belongs to the UPF0303 family
CFBP5473_RS24665	COG1063	alcohol dehydrogenase
CFBP5473_RS24670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5473_RS24675	COG3265	gluconokinase activity
CFBP5473_RS24680	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS24690	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS24710	COG0436	Aminotransferase
CFBP5473_RS24725	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS24780	COG2301	Belongs to the HpcH HpaI aldolase family
CFBP5473_RS24785	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CFBP5473_RS24790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP5473_RS24795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP5473_RS24810	COG1802	Transcriptional regulator
CFBP5473_RS24835	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP5473_RS24845	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5473_RS24855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP5473_RS24860	COG1846	Transcriptional regulator
CFBP5473_RS24870	COG2897	thiosulfate sulfurtransferase activity
CFBP5473_RS24875	COG1116	anion transmembrane transporter activity
CFBP5473_RS24875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5473_RS24880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5473_RS24930	COG3701	Conjugal transfer protein
CFBP5473_RS24935	COG3846	protein secretion by the type IV secretion system
CFBP5473_RS24945	COG5314	conjugation
CFBP5473_RS24950	COG3451	type IV secretory pathway VirB4
CFBP5473_RS24965	COG4962	Type ii secretion system protein e