locus-tag	class	description
FDI40_gp001	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FDI40_gp004	COG0187	DNA topoisomerase II activity
FDI40_gp005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FDI40_gp018	COG0617	tRNA 3'-terminal CCA addition
FDI40_gp070	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FDI40_gp114	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDI40_gp122	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDI40_gp123	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDI40_gp135	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FDI40_gp135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDI40_gp242	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FDI40_gp246	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FDI40_gp253	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDI40_gp263	COG3864	Putative metallopeptidase domain
FDI40_gp282	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FDI40_gp293	COG0484	heat shock protein binding
FDI40_gp303	COG2816	NAD+ diphosphatase activity
FDI40_gp309	COG1702	phosphate starvation-inducible protein PhoH
FDI40_gp492	COG0542	response to heat
FDI40_gp586	COG3201	nicotinamide mononucleotide transporter
FDI40_gp676	COG0740	serine-type endopeptidase activity
FDI40_gp699	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDI40_gp708	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FDI40_gp709	COG1435	thymidine kinase activity