locus-tag	class	description
B0909_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B0909_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B0909_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B0909_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B0909_RS00025	COG1420	regulation of RNA biosynthetic process
B0909_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B0909_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B0909_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B0909_RS00050	COG1137	ATPase activity
B0909_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B0909_RS00065	COG0616	signal peptide processing
B0909_RS00070	COG0776	regulation of translation
B0909_RS00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B0909_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B0909_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B0909_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B0909_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B0909_RS00115	COG0728	peptidoglycan biosynthetic process
B0909_RS00125	COG0180	Tryptophanyl-tRNA synthetase
B0909_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B0909_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B0909_RS00165	COG1702	phosphate starvation-inducible protein PhoH
B0909_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B0909_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B0909_RS00185	COG1396	sequence-specific DNA binding
B0909_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B0909_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B0909_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0909_RS00210	COG0242	peptide deformylase activity
B0909_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B0909_RS00220	COG0101	tRNA pseudouridine synthase activity
B0909_RS00225	COG1393	Belongs to the ArsC family
B0909_RS00235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B0909_RS00240	COG2171	N-acyltransferase activity
B0909_RS00250	COG2972	Histidine kinase
B0909_RS00250	COG0840	transmembrane signaling receptor activity
B0909_RS00260	COG0071	Belongs to the small heat shock protein (HSP20) family
B0909_RS00285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B0909_RS00300	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B0909_RS00305	COG0706	membrane insertase activity
B0909_RS00310	COG0594	ribonuclease P activity
B0909_RS00315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B0909_RS00345	COG2226	methyltransferase
B0909_RS00350	COG3842	ATPase activity
B0909_RS00355	COG1175	transmembrane transport
B0909_RS00360	COG0395	ABC-type sugar transport system, permease component
B0909_RS00375	COG0427	acetyl-CoA hydrolase
B0909_RS00385	COG3938	Belongs to the proline racemase family
B0909_RS00390	COG0418	dihydroorotase activity
B0909_RS00395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B0909_RS00415	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B0909_RS00420	COG0166	Belongs to the GPI family
B0909_RS00425	COG0318	PFAM AMP-dependent synthetase and ligase
B0909_RS00430	COG3842	ATPase activity
B0909_RS00435	COG1840	ABC-type Fe3 transport system, periplasmic component
B0909_RS00440	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B0909_RS00445	COG4774	siderophore transport
B0909_RS00485	COG2326	polyphosphate kinase activity
B0909_RS00490	COG5002	protein histidine kinase activity
B0909_RS00495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B0909_RS00500	COG0573	inorganic phosphate transmembrane transporter activity
B0909_RS00510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B0909_RS00515	COG0704	Plays a role in the regulation of phosphate uptake
B0909_RS00520	COG0745	RESPONSE REGULATOR receiver
B0909_RS00535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B0909_RS00540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B0909_RS00550	COG2967	ApaG domain
B0909_RS00560	COG0717	Belongs to the dCTP deaminase family
B0909_RS00570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B0909_RS00620	COG0167	dihydroorotate dehydrogenase activity
B0909_RS00635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B0909_RS00655	COG1959	2 iron, 2 sulfur cluster binding
B0909_RS00660	COG1201	RNA secondary structure unwinding
B0909_RS00680	COG0730	response to heat
B0909_RS00695	COG1960	acyl-CoA dehydrogenase activity
B0909_RS00700	COG0183	Belongs to the thiolase family
B0909_RS00705	COG1250	3-hydroxyacyl-CoA dehydrogenase
B0909_RS00705	COG1024	Enoyl-CoA hydratase
B0909_RS00735	COG1320	monovalent cation:proton antiporter activity
B0909_RS00740	COG2212	antiporter activity
B0909_RS00745	COG1863	multisubunit Na H antiporter MnhE subunit
B0909_RS00750	COG0651	ATP synthesis coupled electron transport
B0909_RS00755	COG1006	Multisubunit Na H antiporter MnhC subunit
B0909_RS00760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B0909_RS00760	COG2111	Na H antiporter
B0909_RS00770	COG0840	transmembrane signaling receptor activity
B0909_RS00780	COG0745	RESPONSE REGULATOR receiver
B0909_RS00785	COG0643	Histidine kinase
B0909_RS00785	COG2198	Histidine kinase
B0909_RS00790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B0909_RS00795	COG2201	protein-glutamate methylesterase activity
B0909_RS00800	COG0745	RESPONSE REGULATOR receiver
B0909_RS00805	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
B0909_RS00815	COG1766	The M ring may be actively involved in energy transduction
B0909_RS00820	COG2771	luxR family
B0909_RS00830	COG0840	transmembrane signaling receptor activity
B0909_RS00830	COG2972	Histidine kinase
B0909_RS00835	COG0784	Response regulator, receiver
B0909_RS00835	COG2205	protein histidine kinase activity
B0909_RS00835	COG2198	Histidine kinase
B0909_RS00840	COG1970	mechanosensitive ion channel activity
B0909_RS00845	COG0436	Aminotransferase
B0909_RS00860	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
B0909_RS00865	COG0424	maF-like protein
B0909_RS00870	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B0909_RS00880	COG5328	Belongs to the UPF0262 family
B0909_RS00885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B0909_RS00895	COG1881	PFAM PEBP family protein
B0909_RS00905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B0909_RS00940	COG1338	Plays a role in the flagellum-specific transport system
B0909_RS00950	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
B0909_RS00960	COG1706	bacterial-type flagellum-dependent cell motility
B0909_RS00965	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
B0909_RS00970	COG4786	Flagellar basal body rod
B0909_RS00975	COG1677	Flagellar hook-basal body complex protein FliE
B0909_RS00980	COG1558	bacterial-type flagellum-dependent cell motility
B0909_RS00985	COG1815	bacterial-type flagellum-dependent cell motility
B0909_RS00990	COG1280	lysine exporter protein (LysE YggA)
B0909_RS01000	COG1157	protein secretion by the type III secretion system
B0909_RS01005	COG4786	Flagellar basal body rod
B0909_RS01015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B0909_RS01020	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B0909_RS01025	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B0909_RS01030	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B0909_RS01035	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B0909_RS01050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B0909_RS01060	COG1360	Flagellar Motor Protein
B0909_RS01085	COG1749	Flagellar hook protein flgE
B0909_RS01105	COG5443	negative regulation of bacterial-type flagellum assembly
B0909_RS01110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B0909_RS01120	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B0909_RS01160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B0909_RS01165	COG1609	Transcriptional regulator
B0909_RS01170	COG1653	transport
B0909_RS01175	COG1175	transmembrane transport
B0909_RS01180	COG0395	ABC-type sugar transport system, permease component
B0909_RS01185	COG0366	Alpha amylase catalytic
B0909_RS01190	COG3842	ATPase activity
B0909_RS01205	COG0129	dihydroxy-acid dehydratase activity
B0909_RS01210	COG0363	glucosamine-6-phosphate deaminase activity
B0909_RS01215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B0909_RS01220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS01230	COG2081	HI0933 family
B0909_RS01255	COG2224	Isocitrate lyase
B0909_RS01270	COG3842	ATPase activity
B0909_RS01275	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0909_RS01280	COG1177	transmembrane transport
B0909_RS01295	COG2205	protein histidine kinase activity
B0909_RS01415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B0909_RS01435	COG0248	Ppx GppA phosphatase
B0909_RS01440	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B0909_RS01445	COG0477	Major facilitator Superfamily
B0909_RS01480	COG0521	Mo-molybdopterin cofactor biosynthetic process
B0909_RS01485	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B0909_RS01495	COG0142	geranyltranstransferase activity
B0909_RS01520	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B0909_RS01525	COG0752	glycyl-tRNA synthetase alpha subunit
B0909_RS01530	COG1704	LemA family
B0909_RS01535	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B0909_RS01545	COG0751	glycine-tRNA ligase activity
B0909_RS01560	COG0840	transmembrane signaling receptor activity
B0909_RS01570	COG0151	Belongs to the GarS family
B0909_RS01575	COG2183	response to ionizing radiation
B0909_RS01580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B0909_RS01590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B0909_RS01605	COG0583	DNA-binding transcription factor activity
B0909_RS01625	COG0306	phosphate transporter
B0909_RS01635	COG0561	phosphatase activity
B0909_RS01640	COG0438	transferase activity, transferring glycosyl groups
B0909_RS01645	COG2186	Transcriptional regulator
B0909_RS01655	COG0583	DNA-binding transcription factor activity
B0909_RS01660	COG0277	FAD linked oxidase domain protein
B0909_RS01670	COG0277	FAD linked oxidase domain protein
B0909_RS01675	COG0247	lactate metabolic process
B0909_RS01685	COG1376	ErfK ybiS ycfS ynhG family protein
B0909_RS01690	COG2818	Glycosylase
B0909_RS01700	COG2855	membrane
B0909_RS01705	COG0583	DNA-binding transcription factor activity
B0909_RS01735	COG0124	histidyl-tRNA synthetase
B0909_RS01745	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B0909_RS01750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B0909_RS01755	COG2259	Doxx family
B0909_RS01775	COG0459	protein refolding
B0909_RS01780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B0909_RS01790	COG0196	riboflavin kinase activity
B0909_RS01795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B0909_RS01805	COG0590	tRNA wobble adenosine to inosine editing
B0909_RS01810	COG1187	pseudouridine synthase activity
B0909_RS01815	COG0742	ribosomal rna small subunit methyltransferase
B0909_RS01820	COG1752	Esterase of the alpha-beta hydrolase superfamily
B0909_RS01830	COG0312	modulator of DNA gyrase
B0909_RS01835	COG0483	inositol monophosphate 1-phosphatase activity
B0909_RS01845	COG1519	Transferase
B0909_RS01855	COG1663	tetraacyldisaccharide 4'-kinase activity
B0909_RS01865	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B0909_RS01875	COG3300	MHYT domain
B0909_RS01875	COG5001	Diguanylate cyclase
B0909_RS01880	COG3386	PFAM SMP-30 Gluconolaconase
B0909_RS01885	COG0800	Aldolase
B0909_RS01890	COG3734	2-keto-3-deoxy-galactonokinase
B0909_RS01895	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS01905	COG2197	response regulator
B0909_RS01910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0909_RS01920	COG0598	Magnesium transport protein CorA
B0909_RS01925	COG3158	transport of potassium into the cell
B0909_RS01940	COG0356	it plays a direct role in the translocation of protons across the membrane
B0909_RS01950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B0909_RS01955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B0909_RS01965	COG0789	Transcriptional regulator
B0909_RS01970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B0909_RS01995	COG0009	L-threonylcarbamoyladenylate synthase
B0909_RS02005	COG4638	Rieske (2fe-2S)
B0909_RS02030	COG1960	acyl-CoA dehydrogenase activity
B0909_RS02045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B0909_RS02055	COG0840	transmembrane signaling receptor activity
B0909_RS02055	COG2972	Histidine kinase
B0909_RS02065	COG1522	sequence-specific DNA binding
B0909_RS02095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B0909_RS02100	COG1741	Belongs to the pirin family
B0909_RS02105	COG1722	exodeoxyribonuclease VII activity
B0909_RS02110	COG0123	including yeast histone deacetylase and acetoin utilization protein
B0909_RS02115	COG1268	BioY protein
B0909_RS02120	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B0909_RS02125	COG1122	ATPase activity
B0909_RS02130	COG3214	Protein conserved in bacteria
B0909_RS02135	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B0909_RS02135	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B0909_RS02140	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B0909_RS02155	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B0909_RS02170	COG0259	pyridoxamine-phosphate oxidase activity
B0909_RS02190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B0909_RS02200	COG0312	modulator of DNA gyrase
B0909_RS02215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B0909_RS02220	COG0109	protoheme IX farnesyltransferase activity
B0909_RS02230	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
B0909_RS02245	COG3346	SURF1 family
B0909_RS02250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B0909_RS02255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B0909_RS02260	COG0328	RNA-DNA hybrid ribonuclease activity
B0909_RS02270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B0909_RS02270	COG0678	peroxiredoxin activity
B0909_RS02280	COG1678	Uncharacterized ACR, COG1678
B0909_RS02285	COG3237	CsbD-like
B0909_RS02295	COG5001	Diguanylate cyclase
B0909_RS02295	COG3300	MHYT domain
B0909_RS02300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B0909_RS02305	COG0612	Peptidase, M16
B0909_RS02320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B0909_RS02325	COG1802	Transcriptional regulator
B0909_RS02345	COG2189	Belongs to the N(4) N(6)-methyltransferase family
B0909_RS02355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B0909_RS02380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B0909_RS02385	COG1196	nuclear chromosome segregation
B0909_RS02390	COG2514	catechol 2,3-dioxygenase activity
B0909_RS02395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B0909_RS02395	COG0574	Belongs to the PEP-utilizing enzyme family
B0909_RS02410	COG1823	symporter activity
B0909_RS02435	COG0579	oxidoreductase
B0909_RS02455	COG2895	sulfate adenylyltransferase (ATP) activity
B0909_RS02460	COG0175	sulfate reduction
B0909_RS02465	COG0175	sulfate reduction
B0909_RS02470	COG1959	2 iron, 2 sulfur cluster binding
B0909_RS02475	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B0909_RS02480	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B0909_RS02485	COG4208	sulfate ABC transporter
B0909_RS02490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B0909_RS02510	COG2199	diguanylate cyclase activity
B0909_RS02510	COG2200	EAL domain
B0909_RS02510	COG2203	Gaf domain
B0909_RS02525	COG1309	transcriptional regulator
B0909_RS02530	COG1012	belongs to the aldehyde dehydrogenase family
B0909_RS02535	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
B0909_RS02580	COG0477	Major facilitator Superfamily
B0909_RS02600	COG1793	dna ligase
B0909_RS02615	COG1376	ErfK ybiS ycfS ynhG family protein
B0909_RS02620	COG1376	ErfK ybiS ycfS ynhG family protein
B0909_RS02625	COG1846	Transcriptional regulator
B0909_RS02630	COG1764	response to oxidative stress
B0909_RS02670	COG0488	(ABC) transporter
B0909_RS02685	COG0433	COG0433 Predicted ATPase
B0909_RS02700	COG1733	regulation of RNA biosynthetic process
B0909_RS02705	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
B0909_RS02725	COG0656	L-ascorbic acid biosynthetic process
B0909_RS02730	COG3781	membrane
B0909_RS02735	COG2378	regulation of single-species biofilm formation
B0909_RS02745	COG4106	trans-aconitate 2-methyltransferase activity
B0909_RS02750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B0909_RS02755	COG0583	DNA-binding transcription factor activity
B0909_RS02770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B0909_RS02790	COG3909	cytochrome
B0909_RS02795	COG2010	Cytochrome c
B0909_RS02830	COG0789	Transcriptional regulator
B0909_RS02855	COG0517	IMP dehydrogenase activity
B0909_RS02855	COG4175	Glycine betaine
B0909_RS02860	COG4176	ABC-type proline glycine betaine transport system permease component
B0909_RS02890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0909_RS02900	COG2169	Transcriptional regulator
B0909_RS02900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B0909_RS02915	COG2514	catechol 2,3-dioxygenase activity
B0909_RS02930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B0909_RS02935	COG1272	protein, Hemolysin III
B0909_RS02945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B0909_RS02950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B0909_RS02950	COG2111	Na H antiporter
B0909_RS02955	COG2111	Na H antiporter
B0909_RS02960	COG1006	Multisubunit Na H antiporter MnhC subunit
B0909_RS02965	COG0651	ATP synthesis coupled electron transport
B0909_RS02970	COG1863	multisubunit Na H antiporter MnhE subunit
B0909_RS02975	COG2212	antiporter activity
B0909_RS02980	COG1320	monovalent cation:proton antiporter activity
B0909_RS02985	COG4957	zinc ion binding
B0909_RS03000	COG2166	iron-sulfur cluster assembly
B0909_RS03010	COG2205	protein histidine kinase activity
B0909_RS03070	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B0909_RS03075	COG2983	Belongs to the UPF0260 family
B0909_RS03090	COG3077	Addiction module antitoxin, RelB DinJ family
B0909_RS03130	COG2814	Major facilitator Superfamily
B0909_RS03140	COG1621	beta-fructofuranosidase activity
B0909_RS03145	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B0909_RS03165	COG0110	maltose O-acetyltransferase activity
B0909_RS03215	COG4695	Portal protein
B0909_RS03330	COG4235	cytochrome complex assembly
B0909_RS03335	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
B0909_RS03340	COG1138	Cytochrome C-type biogenesis protein
B0909_RS03345	COG3088	subunit of a heme lyase
B0909_RS03350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B0909_RS03365	COG3011	Protein conserved in bacteria
B0909_RS03370	COG3713	MltA-interacting MipA family protein
B0909_RS03375	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B0909_RS03380	COG2205	protein histidine kinase activity
B0909_RS03380	COG2202	Pas domain
B0909_RS03390	COG0308	aminopeptidase N
B0909_RS03395	COG0697	spore germination
B0909_RS03415	COG0443	Heat shock 70 kDa protein
B0909_RS03420	COG5001	Diguanylate cyclase
B0909_RS03420	COG3447	MASE1 domain protein
B0909_RS03420	COG5002	protein histidine kinase activity
B0909_RS03425	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS03445	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B0909_RS03470	COG1733	regulation of RNA biosynthetic process
B0909_RS03480	COG1968	undecaprenyl-diphosphatase activity
B0909_RS03485	COG2239	Acts as a magnesium transporter
B0909_RS03490	COG2814	Major facilitator Superfamily
B0909_RS03515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B0909_RS03545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B0909_RS03590	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B0909_RS03595	COG0741	lytic transglycosylase activity
B0909_RS03605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0909_RS03610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B0909_RS03615	COG0840	transmembrane signaling receptor activity
B0909_RS03625	COG1758	RNA polymerase activity
B0909_RS03650	COG0736	holo-[acyl-carrier-protein] synthase activity
B0909_RS03655	COG0681	Belongs to the peptidase S26 family
B0909_RS03660	COG0571	ribonuclease III activity
B0909_RS03665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B0909_RS03670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B0909_RS03675	COG0784	Response regulator, receiver
B0909_RS03680	COG1381	Involved in DNA repair and RecF pathway recombination
B0909_RS03690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B0909_RS03700	COG1418	mRNA catabolic process
B0909_RS03710	COG0346	lactoylglutathione lyase activity
B0909_RS03720	COG1116	anion transmembrane transporter activity
B0909_RS03725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0909_RS03730	COG3443	Belongs to the bacterial solute-binding protein 9 family
B0909_RS03735	COG0668	transmembrane transport
B0909_RS03745	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
B0909_RS03775	COG1742	UPF0060 membrane protein
B0909_RS03790	COG1183	phosphatidylcholine synthase activity
B0909_RS03795	COG0688	phosphatidylethanolamine metabolic process
B0909_RS03800	COG5265	(ABC) transporter
B0909_RS03845	COG2852	Protein conserved in bacteria
B0909_RS03850	COG0215	cysteine-tRNA ligase activity
B0909_RS03870	COG4221	oxidoreductase activity
B0909_RS03875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B0909_RS03880	COG1286	toxin biosynthetic process
B0909_RS03900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B0909_RS03910	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B0909_RS03920	COG5265	(ABC) transporter
B0909_RS03925	COG0305	Participates in initiation and elongation during chromosome replication
B0909_RS03950	COG0359	binds to the 23S rRNA
B0909_RS03960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B0909_RS03965	COG0360	Binds together with S18 to 16S ribosomal RNA
B0909_RS03975	COG0667	Aldo Keto reductase
B0909_RS03980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B0909_RS03990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B0909_RS03995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B0909_RS04000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B0909_RS04005	COG1561	YicC-like family, N-terminal region
B0909_RS04010	COG0194	GDP metabolic process
B0909_RS04015	COG0400	carboxylic ester hydrolase activity
B0909_RS04020	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B0909_RS04025	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B0909_RS04035	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B0909_RS04050	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B0909_RS04070	COG5001	Diguanylate cyclase
B0909_RS04075	COG4191	Histidine kinase
B0909_RS04080	COG4566	intracellular signal transduction
B0909_RS04090	COG0488	(ABC) transporter
B0909_RS04095	COG3706	GGDEF domain
B0909_RS04105	COG0105	UTP biosynthetic process
B0909_RS04125	COG0314	molybdopterin synthase activity
B0909_RS04135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B0909_RS04140	COG0322	excinuclease ABC activity
B0909_RS04145	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS04155	COG0625	glutathione transferase activity
B0909_RS04170	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B0909_RS04175	COG0243	molybdopterin cofactor binding
B0909_RS04195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B0909_RS04200	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B0909_RS04210	COG0628	permease
B0909_RS04220	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B0909_RS04225	COG0248	Ppx GppA phosphatase
B0909_RS04250	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B0909_RS04260	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B0909_RS04265	COG0477	Major facilitator Superfamily
B0909_RS04270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B0909_RS04275	COG4452	Inner membrane protein CreD
B0909_RS04280	COG0840	transmembrane signaling receptor activity
B0909_RS04285	COG0659	secondary active sulfate transmembrane transporter activity
B0909_RS04295	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B0909_RS04300	COG3654	unkown
B0909_RS04305	COG2336	PFAM SpoVT AbrB
B0909_RS04310	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B0909_RS04320	COG0113	porphobilinogen synthase activity
B0909_RS04345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B0909_RS04350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B0909_RS04355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B0909_RS04355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B0909_RS04365	COG1280	lysine exporter protein (LysE YggA)
B0909_RS04370	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B0909_RS04375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B0909_RS04380	COG2814	Major facilitator Superfamily
B0909_RS04385	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
B0909_RS04405	COG0416	fatty acid biosynthetic process
B0909_RS04410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B0909_RS04415	COG0776	regulation of translation
B0909_RS04450	COG0601	transmembrane transport
B0909_RS04455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS04460	COG0444	Belongs to the ABC transporter superfamily
B0909_RS04465	COG4608	Belongs to the ABC transporter superfamily
B0909_RS04480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B0909_RS04485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B0909_RS04500	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B0909_RS04505	COG0583	DNA-binding transcription factor activity
B0909_RS04520	COG0737	Belongs to the 5'-nucleotidase family
B0909_RS04545	COG2897	thiosulfate sulfurtransferase activity
B0909_RS04560	COG0415	Belongs to the DNA photolyase family
B0909_RS04570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B0909_RS04600	COG3932	Exopolysaccharide synthesis, ExoD
B0909_RS04605	COG1238	metal cluster binding
B0909_RS04680	COG1612	heme a metabolic process
B0909_RS04690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B0909_RS04695	COG0010	Belongs to the arginase family
B0909_RS04700	COG1396	sequence-specific DNA binding
B0909_RS04705	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
B0909_RS04710	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B0909_RS04715	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B0909_RS04725	COG1832	CoA-binding protein
B0909_RS04745	COG2124	cytochrome p450
B0909_RS04750	COG2199	diguanylate cyclase activity
B0909_RS04755	COG0740	serine-type endopeptidase activity
B0909_RS04760	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B0909_RS04775	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B0909_RS04785	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B0909_RS04805	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B0909_RS04810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B0909_RS04815	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B0909_RS04825	COG0649	NAD binding
B0909_RS04835	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
B0909_RS04840	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B0909_RS04850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B0909_RS04855	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B0909_RS04865	COG0713	ATP synthesis coupled electron transport
B0909_RS04880	COG1007	ATP synthesis coupled electron transport
B0909_RS04905	COG0442	prolyl-tRNA aminoacylation
B0909_RS04915	COG1136	(ABC) transporter
B0909_RS04935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B0909_RS04945	COG0784	Response regulator, receiver
B0909_RS04955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B0909_RS04960	COG0477	Major facilitator Superfamily
B0909_RS04975	COG0557	exoribonuclease II activity
B0909_RS04980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B0909_RS04990	COG0758	DNA mediated transformation
B0909_RS04995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B0909_RS05005	COG0540	Belongs to the ATCase OTCase family
B0909_RS05015	COG1960	acyl-CoA dehydrogenase activity
B0909_RS05020	COG0456	acetyltransferase
B0909_RS05045	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B0909_RS05050	COG2824	Alkylphosphonate utilization operon protein PhnA
B0909_RS05055	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B0909_RS05060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B0909_RS05065	COG0154	amidase activity
B0909_RS05070	COG0456	acetyltransferase
B0909_RS05075	COG3811	Belongs to the UPF0386 family
B0909_RS05090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B0909_RS05100	COG0456	acetyltransferase
B0909_RS05115	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B0909_RS05120	COG0439	Biotin carboxylase
B0909_RS05125	COG0511	ligase activity, forming carbon-carbon bonds
B0909_RS05130	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B0909_RS05140	COG0436	Aminotransferase
B0909_RS05160	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS05165	COG1530	ribonuclease E activity
B0909_RS05180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B0909_RS05200	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B0909_RS05205	COG0384	phenazine biosynthesis protein PhzF
B0909_RS05220	COG0633	Ferredoxin
B0909_RS05235	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B0909_RS05240	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B0909_RS05250	COG3768	UPF0283 membrane protein
B0909_RS05255	COG3106	COG3106 Predicted ATPase
B0909_RS05280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B0909_RS05320	COG0537	adenosine 5'-monophosphoramidase activity
B0909_RS05345	COG0052	Belongs to the universal ribosomal protein uS2 family
B0909_RS05350	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B0909_RS05355	COG0528	UMP kinase activity
B0909_RS05360	COG0233	cytoplasmic translational termination
B0909_RS05365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B0909_RS05375	COG0750	zinc metalloprotease
B0909_RS05380	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B0909_RS05385	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B0909_RS05390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B0909_RS05395	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B0909_RS05400	COG3494	Protein of unknown function (DUF1009)
B0909_RS05405	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B0909_RS05410	COG2186	Transcriptional regulator
B0909_RS05420	COG0765	amino acid transport
B0909_RS05425	COG0765	amino acid transport
B0909_RS05435	COG0372	Belongs to the citrate synthase family
B0909_RS05450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B0909_RS05460	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B0909_RS05465	COG0148	phosphopyruvate hydratase activity
B0909_RS05475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B0909_RS05480	COG0508	dehydrogenase complex catalyzes the overall conversion of
B0909_RS05480	COG0022	dehydrogenase e1 component
B0909_RS05485	COG0508	dehydrogenase complex catalyzes the overall conversion of
B0909_RS05495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B0909_RS05505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B0909_RS05510	COG0697	spore germination
B0909_RS05535	COG2867	negative regulation of translational initiation
B0909_RS05540	COG1546	Belongs to the CinA family
B0909_RS05545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B0909_RS05545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B0909_RS05555	COG3852	Histidine kinase
B0909_RS05560	COG2204	response regulator
B0909_RS05565	COG5000	phosphorelay sensor kinase activity
B0909_RS05570	COG2204	response regulator
B0909_RS05575	COG0569	domain protein
B0909_RS05580	COG1923	regulation of RNA biosynthetic process
B0909_RS05585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B0909_RS05590	COG3956	TIGRFAM MazG family protein
B0909_RS05605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B0909_RS05605	COG1648	precorrin-2 dehydrogenase activity
B0909_RS05640	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B0909_RS05640	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B0909_RS05645	COG0509	glycine decarboxylation via glycine cleavage system
B0909_RS05650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B0909_RS05680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B0909_RS05705	COG0251	oxidation-reduction process
B0909_RS05710	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B0909_RS05720	COG1671	Belongs to the UPF0178 family
B0909_RS05735	COG0450	alkyl hydroperoxide reductase
B0909_RS05745	COG0477	Major facilitator Superfamily
B0909_RS05750	COG0625	glutathione transferase activity
B0909_RS05755	COG1280	lysine exporter protein (LysE YggA)
B0909_RS05780	COG2226	methyltransferase
B0909_RS05790	COG0601	transmembrane transport
B0909_RS05805	COG0583	DNA-binding transcription factor activity
B0909_RS05820	COG0321	lipoyl(octanoyl) transferase activity
B0909_RS05820	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B0909_RS05825	COG0084	hydrolase, TatD family'
B0909_RS05830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B0909_RS05840	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B0909_RS05895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B0909_RS05900	COG2095	MarC family integral membrane protein
B0909_RS05905	COG0517	IMP dehydrogenase activity
B0909_RS05905	COG0617	tRNA 3'-terminal CCA addition
B0909_RS05905	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B0909_RS05915	COG0629	single-stranded DNA binding
B0909_RS05920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B0909_RS05935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B0909_RS05940	COG0179	Fumarylacetoacetate (FAA) hydrolase
B0909_RS05955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B0909_RS05960	COG1121	(ABC) transporter
B0909_RS05970	COG1609	Transcriptional regulator
B0909_RS05980	COG0667	Aldo Keto reductase
B0909_RS05990	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B0909_RS06070	COG2239	Acts as a magnesium transporter
B0909_RS06075	COG0243	molybdopterin cofactor binding
B0909_RS06085	COG0242	peptide deformylase activity
B0909_RS06100	COG2202	Pas domain
B0909_RS06100	COG2205	protein histidine kinase activity
B0909_RS06410	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B0909_RS06540	COG0321	lipoyl(octanoyl) transferase activity
B0909_RS06545	COG1064	alcohol dehydrogenase
B0909_RS06575	COG1862	Preprotein translocase
B0909_RS06595	COG2124	cytochrome p450
B0909_RS06610	COG0596	Alpha beta hydrolase
B0909_RS06770	COG3772	lysozyme
B0909_RS06790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B0909_RS06795	COG0626	cystathionine gamma-synthase activity
B0909_RS06800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0909_RS06805	COG4597	amino acid ABC transporter
B0909_RS06810	COG0765	amino acid transport
B0909_RS06815	COG1126	abc transporter atp-binding protein
B0909_RS06835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B0909_RS06850	COG0436	Aminotransferase
B0909_RS06880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B0909_RS06890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B0909_RS06895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B0909_RS06900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B0909_RS06915	COG3243	poly(R)-hydroxyalkanoic acid synthase
B0909_RS06920	COG1489	DNA binding
B0909_RS06925	COG0024	Methionine aminopeptidase
B0909_RS06930	COG2003	Belongs to the UPF0758 family
B0909_RS06945	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B0909_RS06960	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B0909_RS06965	COG0546	phosphoglycolate phosphatase activity
B0909_RS06975	COG0114	fumarate hydratase activity
B0909_RS06985	COG0504	CTP synthase activity
B0909_RS06995	COG0149	triose-phosphate isomerase activity
B0909_RS07005	COG0187	DNA topoisomerase II activity
B0909_RS07015	COG0740	serine-type endopeptidase activity
B0909_RS07025	COG0640	Transcriptional regulator
B0909_RS07030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B0909_RS07035	COG0745	RESPONSE REGULATOR receiver
B0909_RS07045	COG3264	Mechanosensitive ion channel
B0909_RS07045	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
B0909_RS07105	COG1127	ABC transporter
B0909_RS07110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B0909_RS07115	COG4948	Mandelate Racemase Muconate Lactonizing
B0909_RS07125	COG0281	malic enzyme
B0909_RS07125	COG0280	phosphate acetyltransferase
B0909_RS07135	COG0778	Nitroreductase
B0909_RS07140	COG0823	Involved in the tonB-independent uptake of proteins
B0909_RS07155	COG1368	sulfuric ester hydrolase activity
B0909_RS07180	COG0544	peptidyl-prolyl cis-trans isomerase activity
B0909_RS07205	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B0909_RS07225	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B0909_RS07250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B0909_RS07250	COG0512	Glutamine amidotransferase of anthranilate synthase
B0909_RS07255	COG0343	queuine tRNA-ribosyltransferase activity
B0909_RS07260	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B0909_RS07275	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B0909_RS07300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B0909_RS07305	COG0134	indole-3-glycerol-phosphate synthase activity
B0909_RS07310	COG0315	cyclic pyranopterin monophosphate synthase activity
B0909_RS07315	COG0303	'Molybdopterin
B0909_RS07320	COG3706	GGDEF domain
B0909_RS07330	COG0475	glutathione-regulated potassium exporter activity
B0909_RS07330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B0909_RS07340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B0909_RS07345	COG0697	spore germination
B0909_RS07350	COG2814	Major facilitator Superfamily
B0909_RS07355	COG0746	molybdenum cofactor guanylyltransferase activity
B0909_RS07360	COG1763	Mo-molybdopterin cofactor biosynthetic process
B0909_RS07370	COG0739	heme binding
B0909_RS07375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B0909_RS07380	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B0909_RS07385	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B0909_RS07390	COG0805	protein transport
B0909_RS07395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B0909_RS07400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B0909_RS07405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B0909_RS07410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B0909_RS07415	COG1472	Belongs to the glycosyl hydrolase 3 family
B0909_RS07425	COG0018	arginyl-trna synthetase
B0909_RS07430	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B0909_RS07435	COG0316	Belongs to the HesB IscA family
B0909_RS07460	COG0525	valine-tRNA ligase activity
B0909_RS07470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B0909_RS07500	COG0655	NAD(P)H dehydrogenase (quinone) activity
B0909_RS07505	COG1058	Belongs to the CinA family
B0909_RS07505	COG1546	Belongs to the CinA family
B0909_RS07510	COG0589	response to stress
B0909_RS07515	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
B0909_RS07520	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B0909_RS07535	COG1914	H( )-stimulated, divalent metal cation uptake system
B0909_RS07550	COG1132	(ABC) transporter
B0909_RS07555	COG0628	permease
B0909_RS07590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B0909_RS07600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B0909_RS07610	COG0302	gtp cyclohydrolase
B0909_RS07615	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B0909_RS07620	COG1752	Esterase of the alpha-beta hydrolase superfamily
B0909_RS07630	COG0517	IMP dehydrogenase activity
B0909_RS07630	COG0516	GMP reductase activity
B0909_RS07665	COG1760	l-serine dehydratase
B0909_RS07700	COG0583	DNA-binding transcription factor activity
B0909_RS07715	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B0909_RS07715	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B0909_RS07720	COG0347	Belongs to the P(II) protein family
B0909_RS07725	COG0174	glutamine synthetase
B0909_RS07755	COG0697	spore germination
B0909_RS07770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B0909_RS07780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B0909_RS07810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B0909_RS07815	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B0909_RS07820	COG2186	Transcriptional regulator
B0909_RS07830	COG1079	Belongs to the binding-protein-dependent transport system permease family
B0909_RS07835	COG4603	Belongs to the binding-protein-dependent transport system permease family
B0909_RS07840	COG3845	ABC transporter
B0909_RS07845	COG1183	phosphatidylcholine synthase activity
B0909_RS07850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B0909_RS07855	COG0679	Auxin Efflux Carrier
B0909_RS07860	COG0785	Cytochrome C biogenesis protein
B0909_RS07880	COG4221	oxidoreductase activity
B0909_RS07885	COG0583	DNA-binding transcription factor activity
B0909_RS07915	COG1278	Cold shock
B0909_RS07975	COG1136	(ABC) transporter
B0909_RS07975	COG0577	efflux transmembrane transporter activity
B0909_RS07980	COG0577	efflux transmembrane transporter activity
B0909_RS07980	COG1136	(ABC) transporter
B0909_RS08005	COG2151	metal-sulfur cluster biosynthetic enzyme
B0909_RS08010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B0909_RS08015	COG0719	Fe-S assembly protein
B0909_RS08020	COG0396	ATPase activity
B0909_RS08030	COG0719	Fe-S assembly protein
B0909_RS08035	COG1104	cysteine desulfurase activity
B0909_RS08040	COG2945	thiolester hydrolase activity
B0909_RS08050	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B0909_RS08055	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B0909_RS08065	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B0909_RS08070	COG2833	Protein of unknown function (DUF455)
B0909_RS08075	COG0739	heme binding
B0909_RS08080	COG0513	Belongs to the DEAD box helicase family
B0909_RS08105	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B0909_RS08115	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B0909_RS08120	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B0909_RS08125	COG0047	phosphoribosylformylglycinamidine synthase activity
B0909_RS08140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B0909_RS08145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B0909_RS08165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B0909_RS08170	COG2814	Major facilitator Superfamily
B0909_RS08175	COG0483	inositol monophosphate 1-phosphatase activity
B0909_RS08180	COG0483	inositol monophosphate 1-phosphatase activity
B0909_RS08185	COG0037	tRNA processing
B0909_RS08190	COG2066	Belongs to the glutaminase family
B0909_RS08195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B0909_RS08200	COG0861	Integral membrane protein TerC family
B0909_RS08215	COG1280	lysine exporter protein (LysE YggA)
B0909_RS08230	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B0909_RS08235	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
B0909_RS08245	COG0538	isocitrate dehydrogenase activity
B0909_RS08270	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B0909_RS08275	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B0909_RS08280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0909_RS08285	COG2313	pseudouridylate synthase activity
B0909_RS08300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0909_RS08305	COG4215	(ABC) transporter
B0909_RS08315	COG5425	PFAM Usg family protein
B0909_RS08325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0909_RS08330	COG1522	sequence-specific DNA binding
B0909_RS08335	COG1573	uracil-dna glycosylase
B0909_RS08345	COG2202	Pas domain
B0909_RS08345	COG2205	protein histidine kinase activity
B0909_RS08350	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B0909_RS08355	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B0909_RS08360	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B0909_RS08375	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B0909_RS08380	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS08385	COG1129	ABC transporter
B0909_RS08395	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS08400	COG3959	Transketolase, thiamine diphosphate binding domain
B0909_RS08405	COG3958	Transketolase
B0909_RS08410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B0909_RS08415	COG2390	Transcriptional regulator
B0909_RS08425	COG0842	Transport permease protein
B0909_RS08430	COG1131	(ABC) transporter
B0909_RS08455	COG0840	transmembrane signaling receptor activity
B0909_RS08455	COG0840	transmembrane signaling receptor activity
B0909_RS08465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B0909_RS08470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B0909_RS08495	COG0129	dihydroxy-acid dehydratase activity
B0909_RS08500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B0909_RS08505	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
B0909_RS08515	COG0203	ribosomal protein L17
B0909_RS08520	COG0202	RNA polymerase activity
B0909_RS08525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B0909_RS08530	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B0909_RS08535	COG0563	adenylate kinase activity
B0909_RS08540	COG0201	protein transport
B0909_RS08545	COG0200	Binds to the 23S rRNA
B0909_RS08550	COG1841	ribosomal large subunit assembly
B0909_RS08555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B0909_RS08560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B0909_RS08565	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B0909_RS08570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B0909_RS08575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B0909_RS08580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B0909_RS08585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B0909_RS08590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B0909_RS08595	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B0909_RS08600	COG0255	Belongs to the universal ribosomal protein uL29 family
B0909_RS08605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B0909_RS08610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B0909_RS08615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B0909_RS08620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B0909_RS08625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B0909_RS08630	COG0089	rRNA binding
B0909_RS08635	COG0088	Forms part of the polypeptide exit tunnel
B0909_RS08640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B0909_RS08645	COG0051	transcription antitermination factor activity, RNA binding
B0909_RS08650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B0909_RS08655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B0909_RS08660	COG0049	tRNA binding
B0909_RS08665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B0909_RS08685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B0909_RS08690	COG0085	RNA polymerase activity
B0909_RS08695	COG0222	ribosome binding
B0909_RS08700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B0909_RS08705	COG0081	regulation of translation
B0909_RS08710	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B0909_RS08720	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B0909_RS08735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B0909_RS08740	COG0861	Integral membrane protein TerC family
B0909_RS08775	COG1132	(ABC) transporter
B0909_RS08800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B0909_RS08805	COG1607	acyl-coa hydrolase
B0909_RS08830	COG2910	NAD(P)H-binding
B0909_RS08835	COG1733	regulation of RNA biosynthetic process
B0909_RS08850	COG0556	nucleotide-excision repair
B0909_RS08860	COG2382	esterase
B0909_RS08880	COG0484	heat shock protein binding
B0909_RS08905	COG3842	ATPase activity
B0909_RS08910	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B0909_RS08915	COG1840	ABC-type Fe3 transport system, periplasmic component
B0909_RS08920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B0909_RS08935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B0909_RS08945	COG1733	regulation of RNA biosynthetic process
B0909_RS08955	COG2207	Transcriptional regulator
B0909_RS08960	COG1064	alcohol dehydrogenase
B0909_RS08970	COG1252	NADH dehydrogenase
B0909_RS08975	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B0909_RS08985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B0909_RS08990	COG1090	epimerase
B0909_RS09030	COG0656	L-ascorbic acid biosynthetic process
B0909_RS09045	COG0440	acetolactate synthase activity
B0909_RS09050	COG0028	Belongs to the TPP enzyme family
B0909_RS09060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B0909_RS09065	COG3830	Belongs to the UPF0237 family
B0909_RS09065	COG0560	Phosphoserine phosphatase
B0909_RS09075	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS09085	COG0330	HflC and HflK could
B0909_RS09090	COG0330	HflC and HflK could
B0909_RS09100	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B0909_RS09140	COG0277	FAD linked oxidase domain protein
B0909_RS09145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B0909_RS09185	COG1335	isochorismatase
B0909_RS09215	COG2264	protein methyltransferase activity
B0909_RS09220	COG1999	signal sequence binding
B0909_RS09230	COG0835	chemotaxis
B0909_RS09240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B0909_RS09245	COG0583	DNA-binding transcription factor activity
B0909_RS09250	COG0697	spore germination
B0909_RS09255	COG1247	-acetyltransferase
B0909_RS09265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B0909_RS09270	COG0497	DNA recombination
B0909_RS09275	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B0909_RS09285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B0909_RS09290	COG0849	cell division
B0909_RS09295	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B0909_RS09300	COG1181	Belongs to the D-alanine--D-alanine ligase family
B0909_RS09305	COG0477	Major facilitator Superfamily
B0909_RS09310	COG5001	Diguanylate cyclase
B0909_RS09310	COG3300	MHYT domain
B0909_RS09315	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B0909_RS09320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B0909_RS09325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B0909_RS09335	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B0909_RS09340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B0909_RS09350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B0909_RS09365	COG0275	rRNA processing
B0909_RS09370	COG2001	Belongs to the MraZ family
B0909_RS09405	COG3023	N-Acetylmuramoyl-L-alanine amidase
B0909_RS09410	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B0909_RS09435	COG4106	trans-aconitate 2-methyltransferase activity
B0909_RS09455	COG2226	methyltransferase
B0909_RS09465	COG2267	carboxylic ester hydrolase activity
B0909_RS09470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B0909_RS09485	COG0251	oxidation-reduction process
B0909_RS09500	COG1376	ErfK ybiS ycfS ynhG family protein
B0909_RS09505	COG2814	Major facilitator Superfamily
B0909_RS09530	COG1012	belongs to the aldehyde dehydrogenase family
B0909_RS09535	COG0174	glutamine synthetase
B0909_RS09540	COG0531	amino acid
B0909_RS09550	COG1737	Transcriptional regulator
B0909_RS09575	COG3842	ATPase activity
B0909_RS09595	COG0477	Major facilitator Superfamily
B0909_RS09635	COG2968	Membrane
B0909_RS09645	COG0432	Pfam Uncharacterised protein family UPF0047
B0909_RS09665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B0909_RS09670	COG0358	DNA primase activity
B0909_RS09680	COG0505	Belongs to the CarA family
B0909_RS09685	COG0534	Mate efflux family protein
B0909_RS09705	COG2321	neutral zinc metallopeptidase
B0909_RS09720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B0909_RS09730	COG3706	GGDEF domain
B0909_RS09735	COG1573	uracil-dna glycosylase
B0909_RS09745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B0909_RS09755	COG1522	sequence-specific DNA binding
B0909_RS09760	COG0492	ferredoxin-NADP+ reductase activity
B0909_RS09765	COG0583	DNA-binding transcription factor activity
B0909_RS09775	COG1902	pentaerythritol trinitrate reductase activity
B0909_RS09805	COG0387	Pfam Sodium calcium exchanger
B0909_RS09810	COG0436	Aminotransferase
B0909_RS09815	COG2200	EAL domain
B0909_RS09815	COG2199	diguanylate cyclase activity
B0909_RS09830	COG1278	Cold shock
B0909_RS09835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B0909_RS09850	COG1846	Transcriptional regulator
B0909_RS09855	COG0745	RESPONSE REGULATOR receiver
B0909_RS09860	COG2205	protein histidine kinase activity
B0909_RS09865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B0909_RS09885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B0909_RS09895	COG1496	oxidoreductase activity
B0909_RS09910	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B0909_RS09935	COG0840	transmembrane signaling receptor activity
B0909_RS09940	COG1012	belongs to the aldehyde dehydrogenase family
B0909_RS09950	COG3300	MHYT domain
B0909_RS09950	COG5001	Diguanylate cyclase
B0909_RS09955	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B0909_RS09960	COG5001	Diguanylate cyclase
B0909_RS09970	COG0193	aminoacyl-tRNA hydrolase activity
B0909_RS09980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B0909_RS10000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B0909_RS10005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B0909_RS10010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B0909_RS10010	COG2857	Cytochrome c1
B0909_RS10030	COG0840	transmembrane signaling receptor activity
B0909_RS10035	COG1132	(ABC) transporter
B0909_RS10045	COG1132	(ABC) transporter
B0909_RS10050	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B0909_RS10060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B0909_RS10075	COG0408	coproporphyrinogen oxidase activity
B0909_RS10090	COG0617	tRNA 3'-terminal CCA addition
B0909_RS10095	COG0494	nUDIX hydrolase
B0909_RS10105	COG0714	Associated with various cellular activities
B0909_RS10125	COG0454	-acetyltransferase
B0909_RS10140	COG0477	Major facilitator Superfamily
B0909_RS10150	COG0435	Glutathione S-transferase
B0909_RS10155	COG0494	nUDIX hydrolase
B0909_RS10170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B0909_RS10180	COG3135	benzoate transporter
B0909_RS10205	COG0740	serine-type endopeptidase activity
B0909_RS10220	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B0909_RS10225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B0909_RS10255	COG4175	Glycine betaine
B0909_RS10270	COG1435	thymidine kinase activity
B0909_RS10290	COG2862	Uncharacterized protein family, UPF0114
B0909_RS10295	COG4771	TonB-dependent receptor
B0909_RS10295	COG1629	transport
B0909_RS10310	COG0512	Glutamine amidotransferase of anthranilate synthase
B0909_RS10310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B0909_RS10325	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B0909_RS10335	COG0366	Alpha amylase catalytic
B0909_RS10340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0909_RS10360	COG1160	GTP binding
B0909_RS10380	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
B0909_RS10390	COG0024	Methionine aminopeptidase
B0909_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS10420	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B0909_RS10430	COG0583	DNA-binding transcription factor activity
B0909_RS10445	COG0402	S-adenosylhomocysteine deaminase activity
B0909_RS10455	COG1304	FMN binding
B0909_RS10465	COG1309	transcriptional regulator
B0909_RS10470	COG1686	Belongs to the peptidase S11 family
B0909_RS10480	COG2351	hydroxyisourate hydrolase activity
B0909_RS10485	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
B0909_RS10500	COG3195	allantoin biosynthetic process
B0909_RS10500	COG3648	Uricase
B0909_RS10510	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
B0909_RS10515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS10515	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B0909_RS10520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS10520	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B0909_RS10525	COG0784	Response regulator, receiver
B0909_RS10525	COG2205	protein histidine kinase activity
B0909_RS10525	COG5002	protein histidine kinase activity
B0909_RS10530	COG0513	Belongs to the DEAD box helicase family
B0909_RS10540	COG2259	Doxx family
B0909_RS10545	COG1376	ErfK ybiS ycfS ynhG family protein
B0909_RS10555	COG2308	Evidence 4 Homologs of previously reported genes of
B0909_RS10565	COG1305	Transglutaminase-like
B0909_RS10595	COG4214	carbohydrate transport
B0909_RS10605	COG4213	ABC transporter substrate-binding protein
B0909_RS10645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B0909_RS10655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B0909_RS10710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0909_RS10725	COG4974	Belongs to the 'phage' integrase family
B0909_RS10730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0909_RS10755	COG1396	sequence-specific DNA binding
B0909_RS10760	COG1247	-acetyltransferase
B0909_RS10765	COG3238	Protein conserved in bacteria
B0909_RS10770	COG0840	transmembrane signaling receptor activity
B0909_RS10775	COG2814	Major facilitator Superfamily
B0909_RS10785	COG0646	methionine synthase
B0909_RS10785	COG1410	methionine synthase
B0909_RS10830	COG1215	transferase activity, transferring glycosyl groups
B0909_RS10865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B0909_RS10870	COG2346	COG2346, Truncated hemoglobins
B0909_RS10890	COG1309	transcriptional regulator
B0909_RS10905	COG0494	nUDIX hydrolase
B0909_RS10920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0909_RS10925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0909_RS10955	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B0909_RS10960	COG0830	nickel cation binding
B0909_RS10965	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
B0909_RS10980	COG0804	urea catabolic process
B0909_RS10985	COG1442	glycosyl transferase family 8
B0909_RS10990	COG3755	Protein conserved in bacteria
B0909_RS11000	COG0832	Belongs to the urease beta subunit family
B0909_RS11005	COG3813	Protein conserved in bacteria
B0909_RS11010	COG0831	urea catabolic process
B0909_RS11015	COG0829	nickel cation binding
B0909_RS11035	COG0411	ABC transporter
B0909_RS11045	COG0559	Belongs to the binding-protein-dependent transport system permease family
B0909_RS11060	COG0174	glutamine synthetase
B0909_RS11065	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS11070	COG2198	Histidine kinase
B0909_RS11070	COG5002	protein histidine kinase activity
B0909_RS11070	COG0784	Response regulator, receiver
B0909_RS11120	COG1218	3'(2'),5'-bisphosphate nucleotidase
B0909_RS11205	COG0564	pseudouridine synthase activity
B0909_RS11215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B0909_RS11230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B0909_RS11260	COG0346	lactoylglutathione lyase activity
B0909_RS11270	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B0909_RS11280	COG2832	Protein of unknown function (DUF454)
B0909_RS11285	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B0909_RS11290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS11295	COG4558	Periplasmic binding protein
B0909_RS11305	COG3721	Heme iron utilization protein
B0909_RS11325	COG2205	protein histidine kinase activity
B0909_RS11370	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS11375	COG4605	iron ion homeostasis
B0909_RS11380	COG4604	ABC transporter, ATP-binding protein
B0909_RS11385	COG0783	Belongs to the Dps family
B0909_RS11400	COG0656	L-ascorbic acid biosynthetic process
B0909_RS11405	COG2814	Major facilitator Superfamily
B0909_RS11415	COG0583	DNA-binding transcription factor activity
B0909_RS11420	COG0657	acetylesterase activity
B0909_RS11425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0909_RS11445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B0909_RS11450	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B0909_RS11455	COG0288	reversible hydration of carbon dioxide
B0909_RS11465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B0909_RS11485	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B0909_RS11490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B0909_RS11495	COG0778	Nitroreductase
B0909_RS11500	COG2267	carboxylic ester hydrolase activity
B0909_RS11505	COG0251	oxidation-reduction process
B0909_RS11510	COG1335	isochorismatase
B0909_RS11515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS11525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0909_RS11540	COG1175	transmembrane transport
B0909_RS11545	COG0395	ABC-type sugar transport system, permease component
B0909_RS11550	COG3842	ATPase activity
B0909_RS11555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0909_RS11565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B0909_RS11580	COG4608	Belongs to the ABC transporter superfamily
B0909_RS11585	COG0444	Belongs to the ABC transporter superfamily
B0909_RS11590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS11595	COG0601	transmembrane transport
B0909_RS11655	COG1960	acyl-CoA dehydrogenase activity
B0909_RS11685	COG0745	RESPONSE REGULATOR receiver
B0909_RS11695	COG0446	pyridine nucleotide-disulphide oxidoreductase
B0909_RS11695	COG1902	pentaerythritol trinitrate reductase activity
B0909_RS11710	COG4232	protein-disulfide reductase activity
B0909_RS11715	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B0909_RS11715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B0909_RS11725	COG1388	LysM domain
B0909_RS11725	COG1376	ErfK ybiS ycfS ynhG family protein
B0909_RS11735	COG2207	Transcriptional regulator
B0909_RS11735	COG3708	Transcriptional regulator
B0909_RS11745	COG0583	DNA-binding transcription factor activity
B0909_RS11755	COG1335	isochorismatase
B0909_RS11765	COG0583	DNA-binding transcription factor activity
B0909_RS11770	COG0583	DNA-binding transcription factor activity
B0909_RS11775	COG1335	isochorismatase
B0909_RS11795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B0909_RS11805	COG2423	ornithine cyclodeaminase activity
B0909_RS11810	COG0251	oxidation-reduction process
B0909_RS11815	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B0909_RS11820	COG0477	Major facilitator Superfamily
B0909_RS11835	COG0583	DNA-binding transcription factor activity
B0909_RS11845	COG1902	pentaerythritol trinitrate reductase activity
B0909_RS11850	COG1609	Transcriptional regulator
B0909_RS11855	COG0747	negative chemotaxis
B0909_RS11865	COG0601	transmembrane transport
B0909_RS11870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS11880	COG3622	Belongs to the hyi family
B0909_RS11885	COG2084	Dehydrogenase
B0909_RS11915	COG1609	Transcriptional regulator
B0909_RS11920	COG1053	succinate dehydrogenase
B0909_RS11920	COG3976	FMN-binding domain protein
B0909_RS11930	COG1175	transmembrane transport
B0909_RS11935	COG0395	ABC-type sugar transport system, permease component
B0909_RS11940	COG3842	ATPase activity
B0909_RS11990	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B0909_RS12000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0909_RS12005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B0909_RS12015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B0909_RS12040	COG0583	DNA-binding transcription factor activity
B0909_RS12045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS12050	COG0725	ABC transporter, periplasmic molybdate-binding protein
B0909_RS12055	COG4149	molybdate abc transporter
B0909_RS12060	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B0909_RS12070	COG3191	aminopeptidase activity
B0909_RS12075	COG2022	thiamine diphosphate biosynthetic process
B0909_RS12090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B0909_RS12095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B0909_RS12105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B0909_RS12130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B0909_RS12130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B0909_RS12155	COG0438	transferase activity, transferring glycosyl groups
B0909_RS12175	COG4166	transmembrane transport
B0909_RS12180	COG0601	transmembrane transport
B0909_RS12185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS12200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B0909_RS12205	COG3142	Participates in the control of copper homeostasis
B0909_RS12210	COG2814	Major facilitator Superfamily
B0909_RS12225	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS12230	COG1737	Transcriptional regulator
B0909_RS12240	COG3842	ATPase activity
B0909_RS12250	COG0395	ABC-type sugar transport system, permease component
B0909_RS12255	COG1175	transmembrane transport
B0909_RS12270	COG2188	Transcriptional regulator
B0909_RS12275	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B0909_RS12280	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B0909_RS12285	COG1940	carbohydrate kinase activity
B0909_RS12295	COG0671	phosphoesterase, PA-phosphatase related
B0909_RS12300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B0909_RS12305	COG0156	8-amino-7-oxononanoate synthase activity
B0909_RS12315	COG0729	surface antigen
B0909_RS12325	COG0835	chemotaxis
B0909_RS12335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B0909_RS12340	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B0909_RS12345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B0909_RS12350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B0909_RS12355	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B0909_RS12360	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B0909_RS12375	COG4974	Belongs to the 'phage' integrase family
B0909_RS12400	COG1280	lysine exporter protein (LysE YggA)
B0909_RS12410	COG0508	dehydrogenase complex catalyzes the overall conversion of
B0909_RS12415	COG0567	Dehydrogenase, E1 component
B0909_RS12420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B0909_RS12425	COG0045	succinate-CoA ligase (ADP-forming) activity
B0909_RS12430	COG0039	L-malate dehydrogenase activity
B0909_RS12435	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B0909_RS12475	COG2264	protein methyltransferase activity
B0909_RS12490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B0909_RS12495	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B0909_RS12500	COG0181	hydroxymethylbilane synthase activity
B0909_RS12535	COG1872	DUF167
B0909_RS12540	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B0909_RS12550	COG1217	gtp-binding protein TYPA
B0909_RS12555	COG0339	signal peptide processing
B0909_RS12565	COG1846	Transcriptional regulator
B0909_RS12570	COG2814	Major facilitator Superfamily
B0909_RS12575	COG0137	argininosuccinate synthase activity
B0909_RS12585	COG1280	lysine exporter protein (LysE YggA)
B0909_RS12590	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
B0909_RS12595	COG4120	Belongs to the binding-protein-dependent transport system permease family
B0909_RS12605	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B0909_RS12620	COG2154	pterin-4-alpha-carbinolamine dehydratase
B0909_RS12625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B0909_RS12630	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B0909_RS12640	COG4181	ATPase activity
B0909_RS12650	COG0670	Belongs to the BI1 family
B0909_RS12665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B0909_RS12670	COG4133	protoheme IX ABC transporter activity
B0909_RS12680	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B0909_RS12685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B0909_RS12710	COG2917	probably involved in intracellular septation
B0909_RS12715	COG0552	protein localization to endoplasmic reticulum
B0909_RS12720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B0909_RS12725	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B0909_RS12740	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B0909_RS12745	COG1605	Chorismate mutase
B0909_RS12745	COG0287	Prephenate dehydrogenase
B0909_RS12750	COG0228	four-way junction DNA binding
B0909_RS12755	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B0909_RS12760	COG0336	Belongs to the RNA methyltransferase TrmD family
B0909_RS12770	COG0335	large ribosomal subunit rRNA binding
B0909_RS12780	COG0765	amino acid transport
B0909_RS12795	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B0909_RS12820	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
B0909_RS12840	COG0488	(ABC) transporter
B0909_RS12850	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B0909_RS12860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B0909_RS12865	COG0142	geranyltranstransferase activity
B0909_RS12870	COG2885	chlorophyll binding
B0909_RS12875	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B0909_RS12880	COG2223	nitrite transmembrane transporter activity
B0909_RS12885	COG1349	DNA-binding transcription factor activity
B0909_RS12890	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B0909_RS12895	COG2197	response regulator
B0909_RS12900	COG1132	(ABC) transporter
B0909_RS12910	COG3459	Glycosyltransferase 36 associated
B0909_RS12915	COG1473	amidohydrolase
B0909_RS12925	COG0579	oxidoreductase
B0909_RS12935	COG0129	dihydroxy-acid dehydratase activity
B0909_RS12940	COG2084	Dehydrogenase
B0909_RS12945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0909_RS12950	COG0277	FAD linked oxidase domain protein
B0909_RS12955	COG2186	Transcriptional regulator
B0909_RS12965	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B0909_RS12970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0909_RS12975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0909_RS12980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B0909_RS12990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B0909_RS12995	COG0495	leucyl-tRNA aminoacylation
B0909_RS13010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B0909_RS13015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B0909_RS13030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B0909_RS13035	COG1946	Acyl-CoA thioesterase
B0909_RS13040	COG0347	Belongs to the P(II) protein family
B0909_RS13045	COG0004	ammonium transporteR
B0909_RS13050	COG1674	ftsk spoiiie
B0909_RS13055	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B0909_RS13070	COG0745	RESPONSE REGULATOR receiver
B0909_RS13080	COG1329	Transcriptional regulator
B0909_RS13085	COG2902	Dehydrogenase
B0909_RS13090	COG2270	Major facilitator Superfamily
B0909_RS13105	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS13120	COG0494	nUDIX hydrolase
B0909_RS13130	COG0793	Belongs to the peptidase S41A family
B0909_RS13140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B0909_RS13145	COG0799	negative regulation of ribosome biogenesis
B0909_RS13150	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B0909_RS13155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B0909_RS13160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B0909_RS13165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B0909_RS13180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B0909_RS13185	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B0909_RS13210	COG0066	3-isopropylmalate dehydratase activity
B0909_RS13215	COG0473	3-isopropylmalate dehydrogenase activity
B0909_RS13220	COG1858	cytochrome C peroxidase
B0909_RS13225	COG1797	cobyrinic acid a,c-diamide synthase activity
B0909_RS13230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B0909_RS13230	COG1648	precorrin-2 dehydrogenase activity
B0909_RS13235	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
B0909_RS13300	COG1492	cobalamin metabolic process
B0909_RS13315	COG4948	Mandelate Racemase Muconate Lactonizing
B0909_RS13320	COG3254	rhamnose metabolic process
B0909_RS13325	COG0246	Mannitol dehydrogenase
B0909_RS13330	COG1063	alcohol dehydrogenase
B0909_RS13350	COG4214	carbohydrate transport
B0909_RS13355	COG1129	ABC transporter
B0909_RS13360	COG2186	Transcriptional regulator
B0909_RS13365	COG2721	sulfolactate sulfo-lyase activity
B0909_RS13370	COG0138	bifunctional purine biosynthesis protein purh
B0909_RS13380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B0909_RS13380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B0909_RS13385	COG0501	Belongs to the peptidase M48B family
B0909_RS13405	COG0357	Ribosomal RNA small subunit methyltransferase G
B0909_RS13410	COG0445	tRNA wobble uridine modification
B0909_RS13415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B0909_RS13420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B0909_RS13425	COG1981	membrane
B0909_RS13430	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B0909_RS13440	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B0909_RS13445	COG0424	maF-like protein
B0909_RS13450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B0909_RS13455	COG0237	dephospho-CoA kinase activity
B0909_RS13465	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B0909_RS13470	COG3030	protein affecting phage T7 exclusion by the F plasmid
B0909_RS13480	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B0909_RS13505	COG0179	Fumarylacetoacetate (FAA) hydrolase
B0909_RS13520	COG0135	phosphoribosylanthranilate isomerase activity
B0909_RS13525	COG0133	tryptophan synthase activity
B0909_RS13530	COG0159	tryptophan synthase activity
B0909_RS13535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B0909_RS13550	COG1074	ATP-dependent DNA helicase activity
B0909_RS13560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B0909_RS13570	COG2205	protein histidine kinase activity
B0909_RS13580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B0909_RS13585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B0909_RS13590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B0909_RS13590	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B0909_RS13595	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B0909_RS13600	COG0642	Histidine kinase
B0909_RS13605	COG0745	RESPONSE REGULATOR receiver
B0909_RS13610	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B0909_RS13620	COG1652	LysM domain
B0909_RS13625	COG1072	(Pantothenic acid kinase))
B0909_RS13630	COG0140	phosphoribosyl-ATP diphosphatase activity
B0909_RS13635	COG0107	imidazoleglycerol-phosphate synthase activity
B0909_RS13640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B0909_RS13645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B0909_RS13655	COG0131	Imidazoleglycerol-phosphate dehydratase
B0909_RS13660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B0909_RS13665	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B0909_RS13675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B0909_RS13690	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B0909_RS13700	COG1643	Atp-dependent helicase
B0909_RS13745	COG0514	ATP-dependent DNA helicase (RecQ)
B0909_RS13770	COG1072	(Pantothenic acid kinase))
B0909_RS13780	COG1780	Probably involved in ribonucleotide reductase function
B0909_RS13800	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B0909_RS13830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0909_RS13840	COG2813	Specifically methylates the guanine in position
B0909_RS13845	COG1185	polyribonucleotide nucleotidyltransferase activity
B0909_RS13850	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B0909_RS13855	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B0909_RS13860	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B0909_RS13865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B0909_RS13865	COG3064	Membrane
B0909_RS13880	COG0779	Required for maturation of 30S ribosomal subunits
B0909_RS13885	COG2814	Major facilitator Superfamily
B0909_RS13890	COG2951	lytic endotransglycosylase activity
B0909_RS13895	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B0909_RS13905	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B0909_RS13910	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B0909_RS13925	COG2816	NAD+ diphosphatase activity
B0909_RS13930	COG0077	Prephenate dehydratase
B0909_RS13930	COG1605	Chorismate mutase
B0909_RS13935	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B0909_RS13940	COG3474	cytochrome
B0909_RS13950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B0909_RS13955	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B0909_RS13965	COG1278	Cold shock
B0909_RS13975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B0909_RS13985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B0909_RS13985	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B0909_RS13995	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B0909_RS14030	COG2900	Belongs to the SlyX family
B0909_RS14040	COG0484	heat shock protein binding
B0909_RS14045	COG0443	Heat shock 70 kDa protein
B0909_RS14070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B0909_RS14075	COG1744	ABC transporter substrate-binding protein PnrA-like
B0909_RS14080	COG3845	ABC transporter
B0909_RS14085	COG1079	Belongs to the binding-protein-dependent transport system permease family
B0909_RS14090	COG1079	Belongs to the binding-protein-dependent transport system permease family
B0909_RS14095	COG0295	cytidine deaminase activity
B0909_RS14100	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B0909_RS14105	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B0909_RS14110	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B0909_RS14120	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B0909_RS14125	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B0909_RS14130	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B0909_RS14140	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B0909_RS14145	COG1845	cytochrome c oxidase, subunit III
B0909_RS14150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B0909_RS14160	COG0477	Major facilitator Superfamily
B0909_RS14165	COG0069	glutamate synthase activity
B0909_RS14165	COG0070	glutamate synthase
B0909_RS14165	COG0067	glutamate synthase
B0909_RS14170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B0909_RS14185	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B0909_RS14195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B0909_RS14230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0909_RS14250	COG0848	biopolymer transport protein
B0909_RS14260	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B0909_RS14275	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
B0909_RS14280	COG3454	Phosphonate metabolism
B0909_RS14285	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
B0909_RS14290	COG3639	organic phosphonate transmembrane transporter activity
B0909_RS14295	COG3639	organic phosphonate transmembrane transporter activity
B0909_RS14300	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B0909_RS14305	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B0909_RS14315	COG4778	phosphonate C-P lyase system protein PhnL
B0909_RS14320	COG4107	phosphonate C-P lyase system protein PhnK
B0909_RS14325	COG3627	carbon phosphorus lyase activity
B0909_RS14330	COG3626	phosphonate metabolism
B0909_RS14335	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
B0909_RS14340	COG3624	Phosphonate C-P lyase system protein PhnG
B0909_RS14345	COG2188	Transcriptional regulator
B0909_RS14350	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B0909_RS14355	COG0837	glucose binding
B0909_RS14360	COG1803	Methylglyoxal synthase
B0909_RS14365	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
B0909_RS14370	COG4166	transmembrane transport
B0909_RS14375	COG4174	ABC transporter (Permease)
B0909_RS14380	COG4239	(ABC) transporter, permease
B0909_RS14385	COG4172	Belongs to the ABC transporter superfamily
B0909_RS14390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS14395	COG0174	glutamine synthetase
B0909_RS14400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS14405	COG3265	gluconokinase activity
B0909_RS14410	COG1174	glycine betaine transport
B0909_RS14415	COG1125	glycine betaine transport
B0909_RS14420	COG1174	glycine betaine transport
B0909_RS14425	COG1732	Glycine betaine
B0909_RS14435	COG1959	2 iron, 2 sulfur cluster binding
B0909_RS14440	COG1840	ABC-type Fe3 transport system, periplasmic component
B0909_RS14445	COG0501	Belongs to the peptidase M48B family
B0909_RS14450	COG4269	membrane
B0909_RS14465	COG0697	spore germination
B0909_RS14480	COG0791	NLP P60 protein
B0909_RS14490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B0909_RS14530	COG4964	Belongs to the GSP D family
B0909_RS14580	COG3422	double-strand break repair
B0909_RS14585	COG3757	hydrolase, family 25
B0909_RS14590	COG0697	spore germination
B0909_RS14595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B0909_RS14625	COG0481	GTPase activity
B0909_RS14630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B0909_RS14645	COG1396	sequence-specific DNA binding
B0909_RS14660	COG2169	Transcriptional regulator
B0909_RS14660	COG1917	Cupin 2, conserved barrel domain protein
B0909_RS14665	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0909_RS14690	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B0909_RS14695	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B0909_RS14700	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B0909_RS14710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B0909_RS14715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B0909_RS14715	COG0072	phenylalanine-tRNA ligase activity
B0909_RS14720	COG0667	Aldo Keto reductase
B0909_RS14740	COG4977	sequence-specific DNA binding
B0909_RS14765	COG1570	exodeoxyribonuclease VII activity
B0909_RS14770	COG4948	Mandelate Racemase Muconate Lactonizing
B0909_RS14780	COG1846	Transcriptional regulator
B0909_RS14785	COG0697	spore germination
B0909_RS14790	COG2309	aminopeptidase activity
B0909_RS14800	COG1393	Belongs to the ArsC family
B0909_RS14845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B0909_RS14850	COG1111	helicase
B0909_RS14850	COG1205	dead DEAH box helicase
B0909_RS14870	COG0519	Catalyzes the synthesis of GMP from XMP
B0909_RS14870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B0909_RS14885	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
B0909_RS14915	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B0909_RS14925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B0909_RS14935	COG1968	undecaprenyl-diphosphatase activity
B0909_RS14960	COG0284	orotidine-5'-phosphate decarboxylase activity
B0909_RS14970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B0909_RS14980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B0909_RS14985	COG0792	nuclease activity
B0909_RS15000	COG1175	transmembrane transport
B0909_RS15005	COG0395	ABC-type sugar transport system, permease component
B0909_RS15010	COG3842	ATPase activity
B0909_RS15020	COG0189	ligase activity
B0909_RS15025	COG0606	chelatase, subunit chli
B0909_RS15030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B0909_RS15035	COG1280	lysine exporter protein (LysE YggA)
B0909_RS15040	COG0756	dUTP diphosphatase activity
B0909_RS15045	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B0909_RS15050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B0909_RS15065	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B0909_RS15070	COG2226	methyltransferase
B0909_RS15075	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B0909_RS15080	COG1024	Enoyl-CoA hydratase
B0909_RS15085	COG0268	Binds directly to 16S ribosomal RNA
B0909_RS15130	COG0583	DNA-binding transcription factor activity
B0909_RS15150	COG2072	flavoprotein involved in K transport
B0909_RS15155	COG0657	acetylesterase activity
B0909_RS15165	COG2130	NADP-dependent
B0909_RS15185	COG2801	Transposase and inactivated derivatives
B0909_RS15255	COG1120	ATPase activity
B0909_RS15260	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS15265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS15330	COG1012	belongs to the aldehyde dehydrogenase family
B0909_RS15350	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS15355	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS15360	COG1129	ABC transporter
B0909_RS15365	COG1879	ABC-type sugar transport system periplasmic component
B0909_RS15370	COG1349	DNA-binding transcription factor activity
B0909_RS15395	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B0909_RS15495	COG1368	sulfuric ester hydrolase activity
B0909_RS15500	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS15575	COG1082	Xylose isomerase domain protein TIM barrel
B0909_RS15595	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS15600	COG1129	ABC transporter
B0909_RS15620	COG3284	Transcriptional regulator
B0909_RS15625	COG1063	alcohol dehydrogenase
B0909_RS15635	COG0488	(ABC) transporter
B0909_RS15640	COG5265	(ABC) transporter
B0909_RS15645	COG3181	Tripartite tricarboxylate transporter family receptor
B0909_RS15660	COG3842	ATPase activity
B0909_RS15670	COG1840	ABC-type Fe3 transport system, periplasmic component
B0909_RS15675	COG1840	ABC-type Fe3 transport system, periplasmic component
B0909_RS15700	COG0405	Gamma-glutamyltransferase
B0909_RS15705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS15710	COG0601	transmembrane transport
B0909_RS15715	COG0747	negative chemotaxis
B0909_RS15720	COG2186	Transcriptional regulator
B0909_RS15730	COG4948	Mandelate Racemase Muconate Lactonizing
B0909_RS15735	COG4172	Belongs to the ABC transporter superfamily
B0909_RS15740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS15745	COG0601	transmembrane transport
B0909_RS15750	COG0747	negative chemotaxis
B0909_RS15755	COG2186	Transcriptional regulator
B0909_RS15765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0909_RS15770	COG2223	nitrite transmembrane transporter activity
B0909_RS15780	COG3383	formate dehydrogenase (NAD+) activity
B0909_RS15805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B0909_RS15810	COG1802	Transcriptional regulator
B0909_RS15815	COG4608	Belongs to the ABC transporter superfamily
B0909_RS15820	COG0444	Belongs to the ABC transporter superfamily
B0909_RS15825	COG0402	S-adenosylhomocysteine deaminase activity
B0909_RS15835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS15840	COG0601	transmembrane transport
B0909_RS15850	COG0402	S-adenosylhomocysteine deaminase activity
B0909_RS15865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B0909_RS15875	COG0765	amino acid transport
B0909_RS15880	COG0765	amino acid transport
B0909_RS15885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0909_RS15895	COG1609	Transcriptional regulator
B0909_RS15900	COG3938	Belongs to the proline racemase family
B0909_RS15910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS15920	COG0765	amino acid transport
B0909_RS15935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B0909_RS15940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0909_RS15950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B0909_RS15955	COG0784	Response regulator, receiver
B0909_RS15980	COG1486	melibiose metabolic process
B0909_RS15985	COG4172	Belongs to the ABC transporter superfamily
B0909_RS15990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS15995	COG0601	transmembrane transport
B0909_RS16000	COG0747	negative chemotaxis
B0909_RS16005	COG1486	melibiose metabolic process
B0909_RS16030	COG1940	carbohydrate kinase activity
B0909_RS16035	COG2182	Extracellular solute-binding protein
B0909_RS16040	COG1175	transmembrane transport
B0909_RS16045	COG0395	ABC-type sugar transport system, permease component
B0909_RS16050	COG0165	Argininosuccinate lyase
B0909_RS16055	COG3842	ATPase activity
B0909_RS16060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0909_RS16065	COG3119	arylsulfatase activity
B0909_RS16075	COG0583	DNA-binding transcription factor activity
B0909_RS16080	COG1012	belongs to the aldehyde dehydrogenase family
B0909_RS16125	COG1120	ATPase activity
B0909_RS16130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS16135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS16145	COG4774	siderophore transport
B0909_RS16155	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
B0909_RS16200	COG5002	protein histidine kinase activity
B0909_RS16205	COG0745	RESPONSE REGULATOR receiver
B0909_RS16225	COG1392	Phosphate transport regulator
B0909_RS16230	COG0306	phosphate transporter
B0909_RS16235	COG3300	MHYT domain
B0909_RS16235	COG5001	Diguanylate cyclase
B0909_RS16250	COG1312	Catalyzes the dehydration of D-mannonate
B0909_RS16255	COG2186	Transcriptional regulator
B0909_RS16260	COG0601	transmembrane transport
B0909_RS16265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS16270	COG0444	Belongs to the ABC transporter superfamily
B0909_RS16295	COG4774	siderophore transport
B0909_RS16300	COG1120	ATPase activity
B0909_RS16305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS16310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS16325	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
B0909_RS16330	COG1088	dTDP-glucose 4,6-dehydratase activity
B0909_RS16335	COG1091	dTDP-4-dehydrorhamnose reductase activity
B0909_RS16340	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B0909_RS16350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B0909_RS16355	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B0909_RS16360	COG1132	(ABC) transporter
B0909_RS16375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0909_RS16385	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS16395	COG0179	Fumarylacetoacetate (FAA) hydrolase
B0909_RS16405	COG0583	DNA-binding transcription factor activity
B0909_RS16410	COG0667	Aldo Keto reductase
B0909_RS16415	COG0385	Bile acid
B0909_RS16425	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B0909_RS16440	COG0300	oxidoreductase activity
B0909_RS16445	COG0483	inositol monophosphate 1-phosphatase activity
B0909_RS16450	COG0584	glycerophosphoryl diester phosphodiesterase
B0909_RS16460	COG4149	molybdate abc transporter
B0909_RS16465	COG3842	ATPase activity
B0909_RS16475	COG1940	carbohydrate kinase activity
B0909_RS16485	COG3712	iron ion homeostasis
B0909_RS16490	COG4774	siderophore transport
B0909_RS16495	COG2814	Major facilitator Superfamily
B0909_RS16515	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B0909_RS16530	COG1175	transmembrane transport
B0909_RS16535	COG0395	ABC-type sugar transport system, permease component
B0909_RS16540	COG1609	Transcriptional regulator
B0909_RS16550	COG0673	inositol 2-dehydrogenase activity
B0909_RS16555	COG1082	Xylose isomerase domain protein TIM barrel
B0909_RS16570	COG1609	Transcriptional regulator
B0909_RS16580	COG0183	Belongs to the thiolase family
B0909_RS16585	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B0909_RS16595	COG1414	Transcriptional regulator
B0909_RS16610	COG0583	DNA-binding transcription factor activity
B0909_RS16620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B0909_RS16625	COG3485	protocatechuate 3,4-dioxygenase
B0909_RS16630	COG3485	protocatechuate 3,4-dioxygenase
B0909_RS16640	COG0765	amino acid transport
B0909_RS16645	COG0765	amino acid transport
B0909_RS16650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0909_RS16655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0909_RS16660	COG1126	abc transporter atp-binding protein
B0909_RS16665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B0909_RS16670	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B0909_RS16700	COG0747	negative chemotaxis
B0909_RS16710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS16720	COG2207	Transcriptional regulator
B0909_RS16730	COG0683	leucine binding
B0909_RS16775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0909_RS16780	COG3962	Belongs to the TPP enzyme family
B0909_RS16795	COG3718	enzyme involved in inositol metabolism
B0909_RS16805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B0909_RS16815	COG1609	Transcriptional regulator
B0909_RS16820	COG1846	Transcriptional regulator
B0909_RS16830	COG0523	cobalamin synthesis protein
B0909_RS16875	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
B0909_RS16900	COG0800	Aldolase
B0909_RS16905	COG2954	triphosphatase activity
B0909_RS16915	COG1054	Belongs to the UPF0176 family
B0909_RS16920	COG3300	MHYT domain
B0909_RS16920	COG5001	Diguanylate cyclase
B0909_RS16930	COG2011	ABC-type metal ion transport system permease component
B0909_RS16935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B0909_RS16940	COG0778	Nitroreductase
B0909_RS16980	COG0583	DNA-binding transcription factor activity
B0909_RS16985	COG1879	ABC-type sugar transport system periplasmic component
B0909_RS16990	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS16995	COG1129	ABC transporter
B0909_RS17005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B0909_RS17010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0909_RS17015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B0909_RS17020	COG1309	transcriptional regulator
B0909_RS17030	COG3257	ureidoglycine aminohydrolase activity
B0909_RS17040	COG5001	Diguanylate cyclase
B0909_RS17045	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B0909_RS17055	COG0747	negative chemotaxis
B0909_RS17060	COG0601	transmembrane transport
B0909_RS17065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS17070	COG0444	Belongs to the ABC transporter superfamily
B0909_RS17075	COG4608	Belongs to the ABC transporter superfamily
B0909_RS17080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B0909_RS17095	COG0346	lactoylglutathione lyase activity
B0909_RS17105	COG0129	dihydroxy-acid dehydratase activity
B0909_RS17110	COG1879	ABC-type sugar transport system periplasmic component
B0909_RS17115	COG1129	ABC transporter
B0909_RS17120	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS17125	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS17130	COG2186	Transcriptional regulator
B0909_RS17145	COG0523	cobalamin synthesis protein
B0909_RS17150	COG1653	transport
B0909_RS17155	COG1175	transmembrane transport
B0909_RS17160	COG0395	ABC-type sugar transport system, permease component
B0909_RS17165	COG3842	ATPase activity
B0909_RS17175	COG3047	cAMP biosynthetic process
B0909_RS17180	COG2115	Belongs to the xylose isomerase family
B0909_RS17190	COG1070	Carbohydrate kinase
B0909_RS17195	COG1609	Transcriptional regulator
B0909_RS17210	COG1309	transcriptional regulator
B0909_RS17215	COG1253	flavin adenine dinucleotide binding
B0909_RS17220	COG2827	Endonuclease containing a URI domain
B0909_RS17225	COG0471	metal ion transport
B0909_RS17225	COG3273	potassium ion transport
B0909_RS17230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B0909_RS17240	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B0909_RS17245	COG1752	Esterase of the alpha-beta hydrolase superfamily
B0909_RS17255	COG0803	Belongs to the bacterial solute-binding protein 9 family
B0909_RS17260	COG1121	(ABC) transporter
B0909_RS17265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B0909_RS17270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B0909_RS17280	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS17285	COG1414	Transcriptional regulator
B0909_RS17290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B0909_RS17305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B0909_RS17330	COG1069	ribulokinase activity
B0909_RS17355	COG0395	ABC-type sugar transport system, permease component
B0909_RS17360	COG1175	transmembrane transport
B0909_RS17370	COG2390	Transcriptional regulator
B0909_RS17375	COG4172	Belongs to the ABC transporter superfamily
B0909_RS17380	COG1473	amidohydrolase
B0909_RS17390	COG0601	transmembrane transport
B0909_RS17395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS17410	COG0693	protein deglycase activity
B0909_RS17415	COG0154	amidase activity
B0909_RS17420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS17430	COG0747	negative chemotaxis
B0909_RS17435	COG0583	DNA-binding transcription factor activity
B0909_RS17445	COG0444	Belongs to the ABC transporter superfamily
B0909_RS17450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS17455	COG0601	transmembrane transport
B0909_RS17460	COG0747	negative chemotaxis
B0909_RS17475	COG1473	amidohydrolase
B0909_RS17480	COG2814	Major facilitator Superfamily
B0909_RS17485	COG0583	DNA-binding transcription factor activity
B0909_RS17490	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B0909_RS17500	COG3842	ATPase activity
B0909_RS17520	COG1609	Transcriptional regulator
B0909_RS17525	COG0583	DNA-binding transcription factor activity
B0909_RS17530	COG1960	acyl-CoA dehydrogenase activity
B0909_RS17535	COG1629	transport
B0909_RS17535	COG4774	siderophore transport
B0909_RS17545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS17550	COG1120	ATPase activity
B0909_RS17555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS17560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS17570	COG2375	cellular response to nickel ion
B0909_RS17580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B0909_RS17585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B0909_RS17585	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B0909_RS17595	COG1169	isochorismate synthase
B0909_RS17600	COG1021	2,3-dihydroxybenzoate-AMP ligase
B0909_RS17605	COG1535	isochorismatase
B0909_RS17605	COG3433	isochorismatase activity
B0909_RS17610	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS17625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0909_RS17630	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
B0909_RS17635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B0909_RS17640	COG0583	DNA-binding transcription factor activity
B0909_RS17645	COG3005	denitrification pathway
B0909_RS17655	COG0243	molybdopterin cofactor binding
B0909_RS17670	COG4459	periplasmic nitrate reductase
B0909_RS17680	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B0909_RS17705	COG0826	peptidase U32
B0909_RS17715	COG3189	MarR family transcriptional regulator
B0909_RS17720	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B0909_RS17755	COG3256	nitric oxide reductase
B0909_RS17760	COG0714	Associated with various cellular activities
B0909_RS17820	COG0673	inositol 2-dehydrogenase activity
B0909_RS17830	COG1609	Transcriptional regulator
B0909_RS17835	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS17840	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS17845	COG1129	ABC transporter
B0909_RS17850	COG1879	ABC-type sugar transport system periplasmic component
B0909_RS17870	COG0668	transmembrane transport
B0909_RS17885	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B0909_RS17885	COG0446	pyridine nucleotide-disulphide oxidoreductase
B0909_RS17895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS17925	COG1177	transmembrane transport
B0909_RS17930	COG3842	ATPase activity
B0909_RS17950	COG1082	Xylose isomerase domain protein TIM barrel
B0909_RS17955	COG1609	Transcriptional regulator
B0909_RS17960	COG0673	inositol 2-dehydrogenase activity
B0909_RS17975	COG0583	DNA-binding transcription factor activity
B0909_RS18005	COG1609	Transcriptional regulator
B0909_RS18010	COG0673	inositol 2-dehydrogenase activity
B0909_RS18025	COG1175	transmembrane transport
B0909_RS18030	COG0395	ABC-type sugar transport system, permease component
B0909_RS18035	COG3842	ATPase activity
B0909_RS18050	COG2188	Transcriptional regulator
B0909_RS18070	COG0586	Pfam SNARE associated Golgi protein
B0909_RS18075	COG1253	flavin adenine dinucleotide binding
B0909_RS18085	COG0483	inositol monophosphate 1-phosphatase activity
B0909_RS18105	COG3842	ATPase activity
B0909_RS18110	COG1178	ABC-type Fe3 transport system permease component
B0909_RS18140	COG3300	MHYT domain
B0909_RS18140	COG5001	Diguanylate cyclase
B0909_RS18260	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS18270	COG1879	ABC-type sugar transport system periplasmic component
B0909_RS18280	COG1063	alcohol dehydrogenase
B0909_RS18295	COG1136	(ABC) transporter
B0909_RS18310	COG1309	transcriptional regulator
B0909_RS18325	COG1522	sequence-specific DNA binding
B0909_RS18335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B0909_RS18340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B0909_RS18345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B0909_RS18350	COG2423	ornithine cyclodeaminase activity
B0909_RS18355	COG0006	proline dipeptidase activity
B0909_RS18360	COG3608	succinylglutamate desuccinylase aspartoacylase
B0909_RS18365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0909_RS18370	COG0765	amino acid transport
B0909_RS18375	COG0765	amino acid transport
B0909_RS18380	COG1126	abc transporter atp-binding protein
B0909_RS18385	COG0583	DNA-binding transcription factor activity
B0909_RS18390	COG4221	oxidoreductase activity
B0909_RS18430	COG1929	Belongs to the glycerate kinase type-1 family
B0909_RS18435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B0909_RS18440	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS18450	COG0583	DNA-binding transcription factor activity
B0909_RS18475	COG2814	Major facilitator Superfamily
B0909_RS18500	COG2132	Multicopper oxidase
B0909_RS18505	COG0583	DNA-binding transcription factor activity
B0909_RS18510	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B0909_RS18515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0909_RS18520	COG4597	amino acid ABC transporter
B0909_RS18525	COG0765	amino acid transport
B0909_RS18530	COG1126	abc transporter atp-binding protein
B0909_RS18545	COG1609	Transcriptional regulator
B0909_RS18555	COG0673	inositol 2-dehydrogenase activity
B0909_RS18560	COG0363	glucosamine-6-phosphate deaminase activity
B0909_RS18565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B0909_RS18570	COG3842	ATPase activity
B0909_RS18580	COG1175	transmembrane transport
B0909_RS18585	COG0395	ABC-type sugar transport system, permease component
B0909_RS18590	COG1312	Catalyzes the dehydration of D-mannonate
B0909_RS18595	COG0246	Mannitol dehydrogenase
B0909_RS18605	COG1126	abc transporter atp-binding protein
B0909_RS18610	COG0765	amino acid transport
B0909_RS18625	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B0909_RS18635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B0909_RS18650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B0909_RS18660	COG4948	Mandelate Racemase Muconate Lactonizing
B0909_RS18665	COG1414	Transcriptional regulator
B0909_RS18720	COG0739	heme binding
B0909_RS18720	COG1196	nuclear chromosome segregation
B0909_RS18720	COG0741	lytic transglycosylase activity
B0909_RS18725	COG0542	response to heat
B0909_RS18735	COG2890	protein-(glutamine-N5) methyltransferase activity
B0909_RS18740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B0909_RS18750	COG0527	aspartate kinase activity
B0909_RS18770	COG1309	transcriptional regulator
B0909_RS18780	COG0019	diaminopimelate decarboxylase activity
B0909_RS18795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B0909_RS18805	COG3920	Histidine kinase
B0909_RS18815	COG0784	Response regulator, receiver
B0909_RS18830	COG1522	sequence-specific DNA binding
B0909_RS18840	COG1116	anion transmembrane transporter activity
B0909_RS18845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0909_RS18850	COG1012	belongs to the aldehyde dehydrogenase family
B0909_RS18855	COG0583	DNA-binding transcription factor activity
B0909_RS18860	COG0435	Glutathione S-transferase
B0909_RS18870	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B0909_RS18875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0909_RS18880	COG0189	ligase activity
B0909_RS18900	COG4993	Dehydrogenase
B0909_RS18920	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS18925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B0909_RS18970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS18985	COG0246	Mannitol dehydrogenase
B0909_RS18990	COG4608	Belongs to the ABC transporter superfamily
B0909_RS18995	COG0444	Belongs to the ABC transporter superfamily
B0909_RS19000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS19005	COG0601	transmembrane transport
B0909_RS19010	COG0747	negative chemotaxis
B0909_RS19025	COG4221	oxidoreductase activity
B0909_RS19055	COG0539	negative regulation of cytoplasmic translation
B0909_RS19060	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B0909_RS19090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B0909_RS19095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B0909_RS19125	COG1294	oxidase, subunit
B0909_RS19135	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B0909_RS19140	COG4988	ABC transporter
B0909_RS19150	COG1063	alcohol dehydrogenase
B0909_RS19155	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS19160	COG2084	Dehydrogenase
B0909_RS19175	COG1522	sequence-specific DNA binding
B0909_RS19180	COG1794	racemase activity, acting on amino acids and derivatives
B0909_RS19195	COG0058	SHG alpha-glucan phosphorylase activity
B0909_RS19200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B0909_RS19205	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B0909_RS19210	COG0297	glycogen (starch) synthase activity
B0909_RS19215	COG0033	Phosphoglucomutase
B0909_RS19230	COG1733	regulation of RNA biosynthetic process
B0909_RS19245	COG0446	pyridine nucleotide-disulphide oxidoreductase
B0909_RS19245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B0909_RS19260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS19270	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B0909_RS19290	COG1215	transferase activity, transferring glycosyl groups
B0909_RS19295	COG2327	Polysaccharide pyruvyl transferase
B0909_RS19300	COG0463	Glycosyl transferase, family 2
B0909_RS19305	COG2244	polysaccharide biosynthetic process
B0909_RS19310	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B0909_RS19315	COG2273	Hydrolase Family 16
B0909_RS19325	COG1215	transferase activity, transferring glycosyl groups
B0909_RS19330	COG1215	transferase activity, transferring glycosyl groups
B0909_RS19335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B0909_RS19340	COG3206	protein involved in exopolysaccharide biosynthesis
B0909_RS19340	COG0489	protein tyrosine kinase activity
B0909_RS19345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B0909_RS19355	COG4176	ABC-type proline glycine betaine transport system permease component
B0909_RS19360	COG4175	Glycine betaine
B0909_RS19360	COG0517	IMP dehydrogenase activity
B0909_RS19375	COG0564	pseudouridine synthase activity
B0909_RS19380	COG0500	methyltransferase
B0909_RS19390	COG2133	pyrroloquinoline quinone binding
B0909_RS19400	COG2197	response regulator
B0909_RS19405	COG4585	Histidine kinase
B0909_RS19415	COG1879	ABC-type sugar transport system periplasmic component
B0909_RS19420	COG1129	ABC transporter
B0909_RS19425	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS19435	COG3386	PFAM SMP-30 Gluconolaconase
B0909_RS19440	COG2137	regulation of response to DNA damage stimulus
B0909_RS19445	COG3474	cytochrome
B0909_RS19455	COG1120	ATPase activity
B0909_RS19470	COG4774	siderophore transport
B0909_RS19475	COG0583	DNA-binding transcription factor activity
B0909_RS19485	COG2194	sulfuric ester hydrolase activity
B0909_RS19500	COG0477	Major facilitator Superfamily
B0909_RS19520	COG0673	inositol 2-dehydrogenase activity
B0909_RS19530	COG0697	spore germination
B0909_RS19540	COG0010	Belongs to the arginase family
B0909_RS19555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B0909_RS19560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B0909_RS19565	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B0909_RS19575	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B0909_RS19600	COG0745	RESPONSE REGULATOR receiver
B0909_RS19605	COG2205	protein histidine kinase activity
B0909_RS19645	COG0477	Major facilitator Superfamily
B0909_RS19650	COG0583	DNA-binding transcription factor activity
B0909_RS19680	COG2268	Band 7 protein
B0909_RS19685	COG1309	transcriptional regulator
B0909_RS19705	COG0356	it plays a direct role in the translocation of protons across the membrane
B0909_RS19710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B0909_RS19720	COG2706	6-phosphogluconolactonase activity
B0909_RS19760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0909_RS19770	COG0583	DNA-binding transcription factor activity
B0909_RS19780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B0909_RS19785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0909_RS19790	COG2274	protein secretion by the type I secretion system
B0909_RS19810	COG1538	Outer membrane efflux protein
B0909_RS19815	COG2986	histidine ammonia-lyase
B0909_RS19820	COG4175	Glycine betaine
B0909_RS19820	COG0517	IMP dehydrogenase activity
B0909_RS19825	COG4176	ABC-type proline glycine betaine transport system permease component
B0909_RS19865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0909_RS19870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B0909_RS19875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0909_RS19880	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS19885	COG4948	Mandelate Racemase Muconate Lactonizing
B0909_RS19895	COG4948	Mandelate Racemase Muconate Lactonizing
B0909_RS19900	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS19905	COG1063	alcohol dehydrogenase
B0909_RS19915	COG3842	ATPase activity
B0909_RS19920	COG0395	ABC-type sugar transport system, permease component
B0909_RS19945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B0909_RS19955	COG3938	Belongs to the proline racemase family
B0909_RS19960	COG4176	ABC-type proline glycine betaine transport system permease component
B0909_RS19965	COG4176	ABC-type proline glycine betaine transport system permease component
B0909_RS19970	COG4175	Glycine betaine
B0909_RS19970	COG3448	diguanylate cyclase activity
B0909_RS19985	COG1012	belongs to the aldehyde dehydrogenase family
B0909_RS19990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0909_RS19995	COG1802	Transcriptional regulator
B0909_RS20020	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0909_RS20025	COG3842	ATPase activity
B0909_RS20045	COG2072	flavoprotein involved in K transport
B0909_RS20055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0909_RS20060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0909_RS20065	COG1116	anion transmembrane transporter activity
B0909_RS20075	COG1522	sequence-specific DNA binding
B0909_RS20080	COG1733	regulation of RNA biosynthetic process
B0909_RS20100	COG2382	esterase
B0909_RS20110	COG0789	Transcriptional regulator
B0909_RS20115	COG2814	Major facilitator Superfamily
B0909_RS20215	COG0402	S-adenosylhomocysteine deaminase activity
B0909_RS20220	COG1228	amidohydrolase
B0909_RS20225	COG2986	histidine ammonia-lyase
B0909_RS20240	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B0909_RS20270	COG1192	Involved in chromosome partitioning
B0909_RS20275	COG1475	DNA binding
B0909_RS20280	COG1414	Transcriptional regulator
B0909_RS20290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B0909_RS20295	COG4771	TonB-dependent receptor
B0909_RS20305	COG0366	Alpha amylase catalytic
B0909_RS20310	COG4770	biotin carboxylase activity
B0909_RS20315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B0909_RS20320	COG4336	lyase activity
B0909_RS20325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B0909_RS20330	COG1914	H( )-stimulated, divalent metal cation uptake system
B0909_RS20335	COG1802	Transcriptional regulator
B0909_RS20340	COG3707	response regulator
B0909_RS20350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0909_RS20355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0909_RS20360	COG1116	anion transmembrane transporter activity
B0909_RS20365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B0909_RS20380	COG0243	molybdopterin cofactor binding
B0909_RS20385	COG1648	precorrin-2 dehydrogenase activity
B0909_RS20385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B0909_RS20400	COG3842	ATPase activity
B0909_RS20415	COG0395	ABC-type sugar transport system, permease component
B0909_RS20430	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B0909_RS20445	COG0071	Belongs to the small heat shock protein (HSP20) family
B0909_RS20475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B0909_RS20480	COG1879	ABC-type sugar transport system periplasmic component
B0909_RS20485	COG1129	ABC transporter
B0909_RS20500	COG0667	Aldo Keto reductase
B0909_RS20505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B0909_RS20510	COG1830	Aldolase
B0909_RS20515	COG1070	Carbohydrate kinase
B0909_RS20530	COG2076	Multidrug Resistance protein
B0909_RS20540	COG1647	Serine aminopeptidase, S33
B0909_RS20560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B0909_RS20565	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
B0909_RS20605	COG3842	ATPase activity
B0909_RS20610	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0909_RS20615	COG1177	transmembrane transport
B0909_RS20630	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B0909_RS20640	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B0909_RS20655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0909_RS20665	COG4172	Belongs to the ABC transporter superfamily
B0909_RS20670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS20675	COG0601	transmembrane transport
B0909_RS20680	COG4166	transmembrane transport
B0909_RS20685	COG0395	ABC-type sugar transport system, permease component
B0909_RS20755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0909_RS20760	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0909_RS20760	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B0909_RS20770	COG1032	radical SAM domain protein
B0909_RS20785	COG0372	Belongs to the citrate synthase family
B0909_RS20790	COG0372	Belongs to the citrate synthase family
B0909_RS20850	COG4221	oxidoreductase activity
B0909_RS20855	COG0436	Aminotransferase
B0909_RS20865	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B0909_RS20875	COG3842	ATPase activity
B0909_RS20880	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B0909_RS20885	COG1984	allophanate hydrolase subunit 2
B0909_RS20890	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B0909_RS20900	COG0439	Biotin carboxylase
B0909_RS20905	COG0511	ligase activity, forming carbon-carbon bonds
B0909_RS20910	COG0697	spore germination
B0909_RS20915	COG0697	spore germination
B0909_RS20930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B0909_RS20945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0909_RS20955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B0909_RS20960	COG4221	oxidoreductase activity
B0909_RS20965	COG0765	amino acid transport
B0909_RS20970	COG0765	amino acid transport
B0909_RS20980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0909_RS20985	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B0909_RS20990	COG1063	alcohol dehydrogenase
B0909_RS21000	COG0765	amino acid transport
B0909_RS21005	COG0765	amino acid transport
B0909_RS21030	COG1846	Transcriptional regulator
B0909_RS21040	COG1304	FMN binding
B0909_RS21065	COG3842	ATPase activity
B0909_RS21075	COG0395	ABC-type sugar transport system, permease component
B0909_RS21080	COG1175	transmembrane transport
B0909_RS21095	COG2186	Transcriptional regulator
B0909_RS21100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B0909_RS21105	COG0488	(ABC) transporter
B0909_RS21120	COG2307	Protein conserved in bacteria
B0909_RS21120	COG2308	Evidence 4 Homologs of previously reported genes of
B0909_RS21165	COG1454	alcohol dehydrogenase
B0909_RS21170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B0909_RS21180	COG0747	negative chemotaxis
B0909_RS21185	COG0601	transmembrane transport
B0909_RS21190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS21200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0909_RS21215	COG2957	Belongs to the agmatine deiminase family
B0909_RS21220	COG1082	Xylose isomerase domain protein TIM barrel
B0909_RS21225	COG1082	Xylose isomerase domain protein TIM barrel
B0909_RS21230	COG0673	inositol 2-dehydrogenase activity
B0909_RS21235	COG1082	Xylose isomerase domain protein TIM barrel
B0909_RS21255	COG1609	Transcriptional regulator
B0909_RS21265	COG0446	pyridine nucleotide-disulphide oxidoreductase
B0909_RS21265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B0909_RS21270	COG4311	Sarcosine oxidase, delta subunit
B0909_RS21275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS21280	COG4977	sequence-specific DNA binding
B0909_RS21290	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B0909_RS21295	COG2218	PFAM glutamate synthase alpha subunit domain protein
B0909_RS21300	COG0069	glutamate synthase activity
B0909_RS21305	COG0174	glutamine synthetase
B0909_RS21325	COG0765	amino acid transport
B0909_RS21330	COG1126	abc transporter atp-binding protein
B0909_RS21345	COG2267	carboxylic ester hydrolase activity
B0909_RS21355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS21360	COG1012	belongs to the aldehyde dehydrogenase family
B0909_RS21380	COG1177	transmembrane transport
B0909_RS21385	COG3842	ATPase activity
B0909_RS21395	COG1309	transcriptional regulator
B0909_RS21410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B0909_RS21415	COG2186	Transcriptional regulator
B0909_RS21420	COG1027	Aspartate ammonia-lyase
B0909_RS21430	COG0252	asparaginase activity
B0909_RS21440	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B0909_RS21445	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B0909_RS21450	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B0909_RS21455	COG2205	protein histidine kinase activity
B0909_RS21470	COG0070	glutamate synthase
B0909_RS21470	COG0069	glutamate synthase activity
B0909_RS21470	COG0067	glutamate synthase
B0909_RS21480	COG2205	protein histidine kinase activity
B0909_RS21495	COG2951	lytic endotransglycosylase activity
B0909_RS21500	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B0909_RS21530	COG0330	HflC and HflK could
B0909_RS21535	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B0909_RS21540	COG0737	Belongs to the 5'-nucleotidase family
B0909_RS21550	COG5310	Homospermidine synthase
B0909_RS21560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B0909_RS21565	COG1164	Oligoendopeptidase f
B0909_RS21570	COG2204	response regulator
B0909_RS21575	COG3108	Peptidase M15
B0909_RS21580	COG0469	pyruvate kinase activity
B0909_RS21600	COG3750	Belongs to the UPF0335 family
B0909_RS21605	COG0457	Tetratricopeptide repeat
B0909_RS21610	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B0909_RS21615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B0909_RS21620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B0909_RS21650	COG0483	inositol monophosphate 1-phosphatase activity
B0909_RS21670	COG1132	(ABC) transporter
B0909_RS21675	COG0254	rRNA binding
B0909_RS21695	COG3588	fructose-bisphosphate aldolase
B0909_RS21700	COG0126	phosphoglycerate kinase activity
B0909_RS21750	COG1253	flavin adenine dinucleotide binding
B0909_RS21760	COG1692	metallophosphoesterase
B0909_RS21775	COG0217	transcriptional regulatory protein
B0909_RS21780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS21785	COG0840	transmembrane signaling receptor activity
B0909_RS21790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B0909_RS21795	COG0632	four-way junction helicase activity
B0909_RS21800	COG2255	four-way junction helicase activity
B0909_RS21815	COG0494	nUDIX hydrolase
B0909_RS21825	COG0824	Thioesterase
B0909_RS21845	COG0823	Involved in the tonB-independent uptake of proteins
B0909_RS21850	COG2885	chlorophyll binding
B0909_RS21860	COG0037	tRNA processing
B0909_RS21865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B0909_RS21870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B0909_RS21885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B0909_RS21900	COG0482	sulfurtransferase activity
B0909_RS21920	COG3118	belongs to the thioredoxin family
B0909_RS21930	COG2835	tetraacyldisaccharide 4'-kinase activity
B0909_RS21935	COG2373	Large extracellular alpha-helical protein
B0909_RS21940	COG4953	penicillin-binding protein 1C
B0909_RS21955	COG1129	ABC transporter
B0909_RS21960	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS21980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B0909_RS21990	COG1012	belongs to the aldehyde dehydrogenase family
B0909_RS21995	COG0673	inositol 2-dehydrogenase activity
B0909_RS22000	COG3962	Belongs to the TPP enzyme family
B0909_RS22010	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS22020	COG0673	inositol 2-dehydrogenase activity
B0909_RS22075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0909_RS22080	COG1609	Transcriptional regulator
B0909_RS22085	COG4209	transmembrane transport
B0909_RS22090	COG0395	ABC-type sugar transport system, permease component
B0909_RS22105	COG3842	ATPase activity
B0909_RS22125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0909_RS22130	COG1136	(ABC) transporter
B0909_RS22130	COG0577	efflux transmembrane transporter activity
B0909_RS22140	COG1733	regulation of RNA biosynthetic process
B0909_RS22155	COG2072	flavoprotein involved in K transport
B0909_RS22160	COG0583	DNA-binding transcription factor activity
B0909_RS22165	COG1472	Belongs to the glycosyl hydrolase 3 family
B0909_RS22170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B0909_RS22180	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0909_RS22185	COG3842	ATPase activity
B0909_RS22220	COG4691	Plasmid stability protein
B0909_RS22250	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0909_RS22255	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0909_RS22300	COG1473	amidohydrolase
B0909_RS22305	COG1686	Belongs to the peptidase S11 family
B0909_RS22310	COG0523	cobalamin synthesis protein
B0909_RS22315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B0909_RS22315	COG0425	Belongs to the sulfur carrier protein TusA family
B0909_RS22320	COG3034	peptidoglycan biosynthetic process
B0909_RS22325	COG0825	malonyl-CoA metabolic process
B0909_RS22330	COG4974	Belongs to the 'phage' integrase family
B0909_RS22345	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B0909_RS22350	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B0909_RS22385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B0909_RS22390	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B0909_RS22405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B0909_RS22410	COG2226	methyltransferase
B0909_RS22415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B0909_RS22420	COG0287	Prephenate dehydrogenase
B0909_RS22430	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
B0909_RS22450	COG2884	Cell division ATP-binding protein ftsE
B0909_RS22485	COG0165	Argininosuccinate lyase
B0909_RS22490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B0909_RS22500	COG1250	3-hydroxyacyl-CoA dehydrogenase
B0909_RS22510	COG2086	electron transfer activity
B0909_RS22530	COG0300	oxidoreductase activity
B0909_RS22540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B0909_RS22550	COG3800	Transcriptional regulator
B0909_RS22550	COG1396	sequence-specific DNA binding
B0909_RS22555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B0909_RS22560	COG0625	glutathione transferase activity
B0909_RS22570	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
B0909_RS22580	COG4770	biotin carboxylase activity
B0909_RS22585	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B0909_RS22585	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B0909_RS22590	COG0346	lactoylglutathione lyase activity
B0909_RS22605	COG4213	ABC transporter substrate-binding protein
B0909_RS22615	COG4214	carbohydrate transport
B0909_RS22620	COG1129	ABC transporter
B0909_RS22625	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B0909_RS22635	COG1396	sequence-specific DNA binding
B0909_RS22690	COG3833	ABC-type maltose transport systems, permease component
B0909_RS22695	COG3842	ATPase activity
B0909_RS22710	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
B0909_RS22710	COG2273	Hydrolase Family 16
B0909_RS22730	COG0438	transferase activity, transferring glycosyl groups
B0909_RS22735	COG0438	transferase activity, transferring glycosyl groups
B0909_RS22740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B0909_RS22760	COG0489	protein tyrosine kinase activity
B0909_RS22760	COG3206	protein involved in exopolysaccharide biosynthesis
B0909_RS22770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B0909_RS22785	COG2244	polysaccharide biosynthetic process
B0909_RS22800	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B0909_RS22830	COG1733	regulation of RNA biosynthetic process
B0909_RS22865	COG0653	protein targeting
B0909_RS22870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B0909_RS22875	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B0909_RS22885	COG0494	nUDIX hydrolase
B0909_RS22900	COG2226	methyltransferase
B0909_RS22905	COG1040	competence protein
B0909_RS22915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B0909_RS22930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B0909_RS22945	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B0909_RS22960	COG4208	sulfate ABC transporter
B0909_RS22965	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B0909_RS22970	COG4335	DNA alkylation repair
B0909_RS22990	COG5001	Diguanylate cyclase
B0909_RS22995	COG2264	protein methyltransferase activity
B0909_RS23010	COG3254	rhamnose metabolic process
B0909_RS23020	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS23025	COG1129	ABC transporter
B0909_RS23035	COG1349	DNA-binding transcription factor activity
B0909_RS23040	COG3347	Dehydrogenase
B0909_RS23040	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS23045	COG4952	isomerase
B0909_RS23050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B0909_RS23055	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B0909_RS23060	COG1024	Enoyl-CoA hydratase
B0909_RS23075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B0909_RS23080	COG1960	acyl-CoA dehydrogenase activity
B0909_RS23090	COG0183	Belongs to the thiolase family
B0909_RS23095	COG1960	acyl-CoA dehydrogenase activity
B0909_RS23105	COG0022	dehydrogenase e1 component
B0909_RS23120	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B0909_RS23125	COG2391	methyltransferase activity
B0909_RS23135	COG0640	Transcriptional regulator
B0909_RS23140	COG3453	Protein conserved in bacteria
B0909_RS23140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B0909_RS23145	COG2186	Transcriptional regulator
B0909_RS23155	COG0601	transmembrane transport
B0909_RS23165	COG0444	Belongs to the ABC transporter superfamily
B0909_RS23170	COG4608	Belongs to the ABC transporter superfamily
B0909_RS23190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS23195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS23210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS23215	COG1473	amidohydrolase
B0909_RS23220	COG0747	negative chemotaxis
B0909_RS23250	COG2994	toxin metabolic process
B0909_RS23265	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
B0909_RS23270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0909_RS23290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS23295	COG0583	DNA-binding transcription factor activity
B0909_RS23305	COG0667	Aldo Keto reductase
B0909_RS23340	COG1960	acyl-CoA dehydrogenase activity
B0909_RS23370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B0909_RS23380	COG1959	2 iron, 2 sulfur cluster binding
B0909_RS23385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS23390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS23395	COG1473	amidohydrolase
B0909_RS23405	COG1126	abc transporter atp-binding protein
B0909_RS23410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0909_RS23420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS23425	COG1522	sequence-specific DNA binding
B0909_RS23430	COG4172	Belongs to the ABC transporter superfamily
B0909_RS23435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS23475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS23480	COG1012	belongs to the aldehyde dehydrogenase family
B0909_RS23485	COG0473	3-isopropylmalate dehydrogenase activity
B0909_RS23490	COG1012	belongs to the aldehyde dehydrogenase family
B0909_RS23500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B0909_RS23505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B0909_RS23520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS23525	COG1120	ATPase activity
B0909_RS23535	COG2226	methyltransferase
B0909_RS23550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B0909_RS23555	COG1120	ATPase activity
B0909_RS23560	COG1595	DNA-templated transcription, initiation
B0909_RS23580	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
B0909_RS23585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0909_RS23605	COG0673	inositol 2-dehydrogenase activity
B0909_RS23610	COG0673	inositol 2-dehydrogenase activity
B0909_RS23620	COG1175	transmembrane transport
B0909_RS23625	COG0395	ABC-type sugar transport system, permease component
B0909_RS23630	COG3842	ATPase activity
B0909_RS23640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0909_RS23645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B0909_RS23650	COG2197	response regulator
B0909_RS23655	COG0601	transmembrane transport
B0909_RS23660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS23680	COG0747	negative chemotaxis
B0909_RS23695	COG1446	asparaginase
B0909_RS23700	COG0583	DNA-binding transcription factor activity
B0909_RS23705	COG0601	transmembrane transport
B0909_RS23715	COG4172	Belongs to the ABC transporter superfamily
B0909_RS23730	COG1473	amidohydrolase
B0909_RS23745	COG1129	ABC transporter
B0909_RS23750	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS23755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B0909_RS23760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B0909_RS23770	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B0909_RS23790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS23800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS23805	COG2079	MmgE PrpD family protein
B0909_RS23810	COG1126	abc transporter atp-binding protein
B0909_RS23815	COG0765	amino acid transport
B0909_RS23830	COG0280	phosphate acetyltransferase
B0909_RS23830	COG0281	malic enzyme
B0909_RS23850	COG1175	transmembrane transport
B0909_RS23855	COG0395	ABC-type sugar transport system, permease component
B0909_RS23870	COG0673	inositol 2-dehydrogenase activity
B0909_RS23875	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B0909_RS23880	COG0720	synthase
B0909_RS23885	COG0602	queuosine metabolic process
B0909_RS23890	COG0673	inositol 2-dehydrogenase activity
B0909_RS23900	COG3842	ATPase activity
B0909_RS23915	COG1653	transport
B0909_RS23920	COG1609	Transcriptional regulator
B0909_RS23935	COG2094	Belongs to the DNA glycosylase MPG family
B0909_RS23945	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS23955	COG1376	ErfK ybiS ycfS ynhG family protein
B0909_RS23960	COG0840	transmembrane signaling receptor activity
B0909_RS23960	COG2972	Histidine kinase
B0909_RS23965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B0909_RS23980	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B0909_RS23985	COG1596	polysaccharide export
B0909_RS23990	COG3307	-O-antigen
B0909_RS24035	COG2197	response regulator
B0909_RS24045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0909_RS24070	COG2942	2-epimerase
B0909_RS24080	COG1215	transferase activity, transferring glycosyl groups
B0909_RS24100	COG1473	amidohydrolase
B0909_RS24110	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS24115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B0909_RS24125	COG1301	dicarboxylic acid transport
B0909_RS24130	COG4191	Histidine kinase
B0909_RS24135	COG2204	response regulator
B0909_RS24145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B0909_RS24150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B0909_RS24155	COG1522	sequence-specific DNA binding
B0909_RS24165	COG0351	phosphomethylpyrimidine kinase
B0909_RS24170	COG0352	thiamine-phosphate diphosphorylase activity
B0909_RS24175	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B0909_RS24180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B0909_RS24185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0909_RS24195	COG1501	Belongs to the glycosyl hydrolase 31 family
B0909_RS24200	COG0395	ABC-type sugar transport system, permease component
B0909_RS24205	COG1175	transmembrane transport
B0909_RS24210	COG1653	transport
B0909_RS24215	COG3842	ATPase activity
B0909_RS24230	COG4989	oxidoreductase activity
B0909_RS24260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0909_RS24265	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
B0909_RS24270	COG0438	transferase activity, transferring glycosyl groups
B0909_RS24275	COG0747	negative chemotaxis
B0909_RS24280	COG0601	transmembrane transport
B0909_RS24290	COG3964	amidohydrolase
B0909_RS24305	COG1921	L-seryl-tRNASec selenium transferase activity
B0909_RS24315	COG0625	glutathione transferase activity
B0909_RS24330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B0909_RS24335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0909_RS24335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B0909_RS24340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0909_RS24360	COG1312	Catalyzes the dehydration of D-mannonate
B0909_RS24365	COG1063	alcohol dehydrogenase
B0909_RS24370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0909_RS24380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0909_RS24385	COG2186	Transcriptional regulator
B0909_RS24395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B0909_RS24400	COG0850	regulation of cytokinetic process
B0909_RS24405	COG2894	cell division
B0909_RS24410	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B0909_RS24420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B0909_RS24425	COG5001	Diguanylate cyclase
B0909_RS24440	COG0673	inositol 2-dehydrogenase activity
B0909_RS24450	COG1653	transport
B0909_RS24455	COG1175	transmembrane transport
B0909_RS24460	COG0395	ABC-type sugar transport system, permease component
B0909_RS24465	COG3842	ATPase activity
B0909_RS24475	COG0673	inositol 2-dehydrogenase activity
B0909_RS24505	COG0587	DNA-directed DNA polymerase activity
B0909_RS24510	COG2226	methyltransferase
B0909_RS24525	COG0523	cobalamin synthesis protein
B0909_RS24530	COG1121	(ABC) transporter
B0909_RS24540	COG0803	Belongs to the bacterial solute-binding protein 9 family
B0909_RS24545	COG0328	RNA-DNA hybrid ribonuclease activity
B0909_RS24555	COG0626	cystathionine gamma-synthase activity
B0909_RS24560	COG2182	Extracellular solute-binding protein
B0909_RS24565	COG1175	transmembrane transport
B0909_RS24570	COG0395	ABC-type sugar transport system, permease component
B0909_RS24585	COG0395	ABC-type sugar transport system, permease component
B0909_RS24590	COG1175	transmembrane transport
B0909_RS24595	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
B0909_RS24600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B0909_RS24610	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS24615	COG1063	alcohol dehydrogenase
B0909_RS24620	COG1609	Transcriptional regulator
B0909_RS24635	COG2084	Dehydrogenase
B0909_RS24640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B0909_RS24650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B0909_RS24655	COG0583	DNA-binding transcription factor activity
B0909_RS24660	COG2223	nitrite transmembrane transporter activity
B0909_RS24665	COG4977	sequence-specific DNA binding
B0909_RS24695	COG0667	Aldo Keto reductase
B0909_RS24710	COG2186	Transcriptional regulator
B0909_RS24715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B0909_RS24720	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
B0909_RS24725	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS24730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0909_RS24735	COG4948	Mandelate Racemase Muconate Lactonizing
B0909_RS24740	COG3618	amidohydrolase
B0909_RS24750	COG1175	transmembrane transport
B0909_RS24755	COG0395	ABC-type sugar transport system, permease component
B0909_RS24760	COG3842	ATPase activity
B0909_RS24775	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B0909_RS24800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B0909_RS24805	COG0577	efflux transmembrane transporter activity
B0909_RS24805	COG1136	(ABC) transporter
B0909_RS24820	COG1278	Cold shock
B0909_RS24825	COG0673	inositol 2-dehydrogenase activity
B0909_RS24840	COG0673	inositol 2-dehydrogenase activity
B0909_RS24845	COG1309	transcriptional regulator
B0909_RS24850	COG1653	transport
B0909_RS24855	COG1175	transmembrane transport
B0909_RS24860	COG0395	ABC-type sugar transport system, permease component
B0909_RS24865	COG3842	ATPase activity
B0909_RS24870	COG1082	Xylose isomerase domain protein TIM barrel
B0909_RS24875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B0909_RS24885	COG1609	Transcriptional regulator
B0909_RS24915	COG1175	transmembrane transport
B0909_RS24920	COG0395	ABC-type sugar transport system, permease component
B0909_RS24925	COG3842	ATPase activity
B0909_RS24930	COG0395	ABC-type sugar transport system, permease component
B0909_RS24935	COG1175	transmembrane transport
B0909_RS24940	COG1653	transport
B0909_RS24970	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B0909_RS25000	COG3842	ATPase activity
B0909_RS25010	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0909_RS25015	COG0395	ABC-type sugar transport system, permease component
B0909_RS25045	COG5001	Diguanylate cyclase
B0909_RS25050	COG2233	PERMEase
B0909_RS25055	COG0583	DNA-binding transcription factor activity
B0909_RS25060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B0909_RS25070	COG0583	DNA-binding transcription factor activity
B0909_RS25075	COG2828	Protein conserved in bacteria
B0909_RS25090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B0909_RS25095	COG3734	2-keto-3-deoxy-galactonokinase
B0909_RS25100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B0909_RS25105	COG4948	Mandelate Racemase Muconate Lactonizing
B0909_RS25115	COG1175	transmembrane transport
B0909_RS25120	COG0395	ABC-type sugar transport system, permease component
B0909_RS25125	COG3842	ATPase activity
B0909_RS25130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B0909_RS25135	COG1414	Transcriptional regulator
B0909_RS25140	COG1028	Short-chain dehydrogenase reductase Sdr
B0909_RS25145	COG0483	inositol monophosphate 1-phosphatase activity
B0909_RS25155	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B0909_RS25160	COG0395	ABC-type sugar transport system, permease component
B0909_RS25175	COG0840	transmembrane signaling receptor activity
B0909_RS25205	COG1175	transmembrane transport
B0909_RS25210	COG3842	ATPase activity
B0909_RS25280	COG0640	Transcriptional regulator
B0909_RS25365	COG1595	DNA-templated transcription, initiation
B0909_RS25370	COG0110	maltose O-acetyltransferase activity
B0909_RS25395	COG0583	DNA-binding transcription factor activity
B0909_RS25405	COG2814	Major facilitator Superfamily
B0909_RS25425	COG0270	DNA (cytosine-5-)-methyltransferase activity
B0909_RS25445	COG1349	DNA-binding transcription factor activity
B0909_RS25450	COG0840	transmembrane signaling receptor activity
B0909_RS25450	COG2972	Histidine kinase
B0909_RS25455	COG1940	carbohydrate kinase activity
B0909_RS25465	COG1879	ABC-type sugar transport system periplasmic component
B0909_RS25475	COG1172	Belongs to the binding-protein-dependent transport system permease family
B0909_RS25490	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B0909_RS25500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B0909_RS25505	COG0563	adenylate kinase activity
B0909_RS25510	COG0840	transmembrane signaling receptor activity
B0909_RS25510	COG2972	Histidine kinase
B0909_RS25520	COG0191	fructose-bisphosphate aldolase activity
B0909_RS25525	COG0149	triose-phosphate isomerase activity
B0909_RS25535	COG1396	sequence-specific DNA binding
B0909_RS25575	COG1475	DNA binding
B0909_RS25615	COG4227	nucleotidyltransferase activity
B0909_RS25620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B0909_RS25630	COG5489	Protein of unknown function (DUF736)
B0909_RS25635	COG3831	ATPase activity
B0909_RS25645	COG1879	ABC-type sugar transport system periplasmic component
B0909_RS25650	COG0840	transmembrane signaling receptor activity
B0909_RS25665	COG3505	Type IV secretory pathway VirD4
B0909_RS25680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B0909_RS25685	COG4959	Type IV secretory pathway protease TraF
B0909_RS25690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B0909_RS25710	COG2771	luxR family
B0909_RS25715	COG2948	multi-organism process
B0909_RS25725	COG3504	Conjugal transfer protein
B0909_RS25730	COG3701	Conjugal transfer protein
B0909_RS25735	COG3846	protein secretion by the type IV secretion system
B0909_RS25745	COG5314	conjugation
B0909_RS25750	COG3451	type IV secretory pathway VirB4
B0909_RS25755	COG5268	conjugation
B0909_RS25760	COG3838	Conjugal transfer protein Trbc
B0909_RS25765	COG4962	Type ii secretion system protein e
B0909_RS25770	COG3916	Acyl-homoserine-lactone synthase
B0909_RS25775	COG1192	Involved in chromosome partitioning
B0909_RS25780	COG1475	DNA binding
B0909_RS25785	COG0640	Transcriptional regulator
B0909_RS25825	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B0909_RS25845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B0909_RS25990	COG1192	Involved in chromosome partitioning
B0909_RS26040	COG4974	Belongs to the 'phage' integrase family
B0909_RS26045	COG0582	viral genome integration into host DNA
B0909_RS26050	COG4974	Belongs to the 'phage' integrase family
B0909_RS26060	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B0909_RS26140	COG0765	amino acid transport
B0909_RS26155	COG0145	ligase activity
B0909_RS26190	COG3842	ATPase activity
B0909_RS26195	COG1176	ABC-type spermidine putrescine transport system, permease component I
B0909_RS26200	COG1177	transmembrane transport
B0909_RS26210	COG1228	amidohydrolase
B0909_RS26220	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B0909_RS26285	COG4302	ethanolamine ammonia-lyase activity
B0909_RS26290	COG4303	Ethanolamine ammonia lyase large subunit
B0909_RS26300	COG0154	amidase activity
B0909_RS26315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B0909_RS26320	COG4172	Belongs to the ABC transporter superfamily
B0909_RS26325	COG1349	DNA-binding transcription factor activity
B0909_RS26330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls