locus-tag	class	description
F3X89_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F3X89_RS00020	COG0697	spore germination
F3X89_RS00025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3X89_RS00030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F3X89_RS00040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F3X89_RS00045	COG1420	regulation of RNA biosynthetic process
F3X89_RS00055	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F3X89_RS00060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3X89_RS00065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F3X89_RS00075	COG1137	ATPase activity
F3X89_RS00080	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F3X89_RS00090	COG0616	signal peptide processing
F3X89_RS00095	COG0776	regulation of translation
F3X89_RS00120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F3X89_RS00125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3X89_RS00130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F3X89_RS00150	COG0280	phosphate acetyltransferase
F3X89_RS00150	COG0281	malic enzyme
F3X89_RS00155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F3X89_RS00185	COG0180	Tryptophanyl-tRNA synthetase
F3X89_RS00195	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F3X89_RS00220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F3X89_RS00225	COG1702	phosphate starvation-inducible protein PhoH
F3X89_RS00230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F3X89_RS00240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F3X89_RS00245	COG1396	sequence-specific DNA binding
F3X89_RS00250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F3X89_RS00255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F3X89_RS00265	COG0071	Belongs to the small heat shock protein (HSP20) family
F3X89_RS00275	COG0840	transmembrane signaling receptor activity
F3X89_RS00280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_RS00290	COG0242	peptide deformylase activity
F3X89_RS00305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F3X89_RS00310	COG0101	tRNA pseudouridine synthase activity
F3X89_RS00315	COG0579	oxidoreductase
F3X89_RS00325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_RS00330	COG2171	N-acyltransferase activity
F3X89_RS00340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3X89_RS00360	COG0300	oxidoreductase activity
F3X89_RS00365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F3X89_RS00380	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
F3X89_RS00385	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F3X89_RS00390	COG3708	Transcriptional regulator
F3X89_RS00390	COG2207	Transcriptional regulator
F3X89_RS00400	COG0706	membrane insertase activity
F3X89_RS00405	COG0594	ribonuclease P activity
F3X89_RS00410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F3X89_RS00415	COG2972	Histidine kinase
F3X89_RS00415	COG0840	transmembrane signaling receptor activity
F3X89_RS00440	COG1733	regulation of RNA biosynthetic process
F3X89_RS00460	COG0477	Major facilitator Superfamily
F3X89_RS00480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F3X89_RS00490	COG0583	DNA-binding transcription factor activity
F3X89_RS00495	COG0300	oxidoreductase activity
F3X89_RS00500	COG0667	Aldo Keto reductase
F3X89_RS00510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS00515	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS00520	COG3938	Belongs to the proline racemase family
F3X89_RS00550	COG1072	(Pantothenic acid kinase))
F3X89_RS00555	COG0418	dihydroorotase activity
F3X89_RS00565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F3X89_RS00575	COG0166	Belongs to the GPI family
F3X89_RS00580	COG0318	PFAM AMP-dependent synthetase and ligase
F3X89_RS00590	COG0346	lactoylglutathione lyase activity
F3X89_RS00595	COG3795	YCII-related domain
F3X89_RS00600	COG1174	glycine betaine transport
F3X89_RS00605	COG1125	glycine betaine transport
F3X89_RS00610	COG1174	glycine betaine transport
F3X89_RS00615	COG1732	Glycine betaine
F3X89_RS00620	COG0583	DNA-binding transcription factor activity
F3X89_RS00655	COG2326	polyphosphate kinase activity
F3X89_RS00660	COG5002	protein histidine kinase activity
F3X89_RS00670	COG0573	inorganic phosphate transmembrane transporter activity
F3X89_RS00675	COG0581	inorganic phosphate transmembrane transporter activity
F3X89_RS00680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F3X89_RS00685	COG0704	Plays a role in the regulation of phosphate uptake
F3X89_RS00690	COG0745	RESPONSE REGULATOR receiver
F3X89_RS00700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3X89_RS00705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F3X89_RS00710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
F3X89_RS00715	COG2967	ApaG domain
F3X89_RS00725	COG0717	Belongs to the dCTP deaminase family
F3X89_RS00735	COG0110	maltose O-acetyltransferase activity
F3X89_RS00770	COG0167	dihydroorotate dehydrogenase activity
F3X89_RS00775	COG0534	Mate efflux family protein
F3X89_RS00795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3X89_RS00805	COG0174	glutamine synthetase
F3X89_RS00810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3X89_RS00815	COG1959	2 iron, 2 sulfur cluster binding
F3X89_RS00820	COG1201	RNA secondary structure unwinding
F3X89_RS00845	COG0730	response to heat
F3X89_RS00860	COG1960	acyl-CoA dehydrogenase activity
F3X89_RS00865	COG0183	Belongs to the thiolase family
F3X89_RS00870	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3X89_RS00870	COG1024	Enoyl-CoA hydratase
F3X89_RS00885	COG1970	mechanosensitive ion channel activity
F3X89_RS00890	COG0436	Aminotransferase
F3X89_RS00925	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS00935	COG1024	Enoyl-CoA hydratase
F3X89_RS00965	COG4651	solute:proton antiporter activity
F3X89_RS00965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3X89_RS00975	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F3X89_RS00980	COG0840	transmembrane signaling receptor activity
F3X89_RS00990	COG0745	RESPONSE REGULATOR receiver
F3X89_RS00995	COG2198	Histidine kinase
F3X89_RS00995	COG0643	Histidine kinase
F3X89_RS01000	COG0835	chemotaxis
F3X89_RS01005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F3X89_RS01010	COG2201	protein-glutamate methylesterase activity
F3X89_RS01015	COG0745	RESPONSE REGULATOR receiver
F3X89_RS01020	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
F3X89_RS01030	COG1766	The M ring may be actively involved in energy transduction
F3X89_RS01035	COG2771	luxR family
F3X89_RS01050	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3X89_RS01055	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3X89_RS01060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3X89_RS01065	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3X89_RS01070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F3X89_RS01075	COG4786	Flagellar basal body rod
F3X89_RS01080	COG1157	protein secretion by the type III secretion system
F3X89_RS01090	COG1815	bacterial-type flagellum-dependent cell motility
F3X89_RS01095	COG1558	bacterial-type flagellum-dependent cell motility
F3X89_RS01100	COG1677	Flagellar hook-basal body complex protein FliE
F3X89_RS01105	COG4786	Flagellar basal body rod
F3X89_RS01110	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
F3X89_RS01115	COG1706	bacterial-type flagellum-dependent cell motility
F3X89_RS01125	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
F3X89_RS01135	COG1338	Plays a role in the flagellum-specific transport system
F3X89_RS01155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3X89_RS01165	COG0076	glutamate decarboxylase activity
F3X89_RS01175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3X89_RS01210	COG1749	Flagellar hook protein flgE
F3X89_RS01230	COG5443	negative regulation of bacterial-type flagellum assembly
F3X89_RS01240	COG4794	Type iii secretion
F3X89_RS01245	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3X89_RS01250	COG1684	flagellar biosynthetic protein fliR
F3X89_RS01285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F3X89_RS01290	COG1609	Transcriptional regulator
F3X89_RS01295	COG1653	transport
F3X89_RS01300	COG1175	transmembrane transport
F3X89_RS01305	COG0395	ABC-type sugar transport system, permease component
F3X89_RS01310	COG0366	Alpha amylase catalytic
F3X89_RS01315	COG3842	ATPase activity
F3X89_RS01335	COG0129	dihydroxy-acid dehydratase activity
F3X89_RS01340	COG0363	glucosamine-6-phosphate deaminase activity
F3X89_RS01345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F3X89_RS01350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS01360	COG2081	HI0933 family
F3X89_RS01375	COG0840	transmembrane signaling receptor activity
F3X89_RS01375	COG2972	Histidine kinase
F3X89_RS01390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3X89_RS01395	COG3842	ATPase activity
F3X89_RS01400	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_RS01405	COG1177	transmembrane transport
F3X89_RS01415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3X89_RS01420	COG0513	Belongs to the DEAD box helicase family
F3X89_RS01430	COG2205	protein histidine kinase activity
F3X89_RS01470	COG4269	membrane
F3X89_RS01480	COG1959	2 iron, 2 sulfur cluster binding
F3X89_RS01485	COG0747	negative chemotaxis
F3X89_RS01490	COG0601	transmembrane transport
F3X89_RS01495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS01500	COG0444	Belongs to the ABC transporter superfamily
F3X89_RS01505	COG4608	Belongs to the ABC transporter superfamily
F3X89_RS01510	COG3265	gluconokinase activity
F3X89_RS01515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS01520	COG1755	Isoprenylcysteine carboxyl methyltransferase
F3X89_RS01535	COG1595	DNA-templated transcription, initiation
F3X89_RS01550	COG0583	DNA-binding transcription factor activity
F3X89_RS01560	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F3X89_RS01570	COG0477	Major facilitator Superfamily
F3X89_RS01600	COG0583	DNA-binding transcription factor activity
F3X89_RS01610	COG0488	(ABC) transporter
F3X89_RS01640	COG0306	phosphate transporter
F3X89_RS01655	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F3X89_RS01660	COG0583	DNA-binding transcription factor activity
F3X89_RS01665	COG0277	FAD linked oxidase domain protein
F3X89_RS01670	COG0277	FAD linked oxidase domain protein
F3X89_RS01675	COG0247	lactate metabolic process
F3X89_RS01690	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_RS01695	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_RS01700	COG2818	Glycosylase
F3X89_RS01715	COG0667	Aldo Keto reductase
F3X89_RS01720	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS01720	COG0604	alcohol dehydrogenase
F3X89_RS01720	COG3321	synthase
F3X89_RS01725	COG0583	DNA-binding transcription factor activity
F3X89_RS01750	COG0124	histidyl-tRNA synthetase
F3X89_RS01755	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
F3X89_RS01760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F3X89_RS01775	COG2259	Doxx family
F3X89_RS01780	COG0625	glutathione transferase activity
F3X89_RS01795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F3X89_RS01810	COG0196	riboflavin kinase activity
F3X89_RS01845	COG0590	tRNA wobble adenosine to inosine editing
F3X89_RS01850	COG1187	pseudouridine synthase activity
F3X89_RS01855	COG0742	ribosomal rna small subunit methyltransferase
F3X89_RS01865	COG0475	glutathione-regulated potassium exporter activity
F3X89_RS01865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3X89_RS01870	COG0312	modulator of DNA gyrase
F3X89_RS01875	COG0483	inositol monophosphate 1-phosphatase activity
F3X89_RS01885	COG1519	Transferase
F3X89_RS01895	COG1663	tetraacyldisaccharide 4'-kinase activity
F3X89_RS01905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F3X89_RS01910	COG0745	RESPONSE REGULATOR receiver
F3X89_RS01915	COG3300	MHYT domain
F3X89_RS01915	COG5001	Diguanylate cyclase
F3X89_RS01920	COG1522	sequence-specific DNA binding
F3X89_RS01925	COG0137	argininosuccinate synthase activity
F3X89_RS01935	COG3386	PFAM SMP-30 Gluconolaconase
F3X89_RS01940	COG0800	Aldolase
F3X89_RS01945	COG3734	2-keto-3-deoxy-galactonokinase
F3X89_RS01950	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS01955	COG1414	Transcriptional regulator
F3X89_RS01960	COG2197	response regulator
F3X89_RS01965	COG0489	protein tyrosine kinase activity
F3X89_RS01970	COG0598	Magnesium transport protein CorA
F3X89_RS01975	COG3158	transport of potassium into the cell
F3X89_RS01990	COG0356	it plays a direct role in the translocation of protons across the membrane
F3X89_RS01995	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F3X89_RS02000	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F3X89_RS02005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F3X89_RS02015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F3X89_RS02035	COG0521	Mo-molybdopterin cofactor biosynthetic process
F3X89_RS02040	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
F3X89_RS02050	COG0142	geranyltranstransferase activity
F3X89_RS02070	COG1396	sequence-specific DNA binding
F3X89_RS02105	COG0752	glycyl-tRNA synthetase alpha subunit
F3X89_RS02110	COG1704	LemA family
F3X89_RS02115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F3X89_RS02130	COG0751	glycine-tRNA ligase activity
F3X89_RS02135	COG1683	Conserved Protein
F3X89_RS02140	COG0840	transmembrane signaling receptor activity
F3X89_RS02150	COG0151	Belongs to the GarS family
F3X89_RS02155	COG2183	response to ionizing radiation
F3X89_RS02160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3X89_RS02180	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F3X89_RS02205	COG0277	FAD linked oxidase domain protein
F3X89_RS02210	COG0009	L-threonylcarbamoyladenylate synthase
F3X89_RS02225	COG4638	Rieske (2fe-2S)
F3X89_RS02250	COG1960	acyl-CoA dehydrogenase activity
F3X89_RS02260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F3X89_RS02270	COG0840	transmembrane signaling receptor activity
F3X89_RS02280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F3X89_RS02285	COG1741	Belongs to the pirin family
F3X89_RS02290	COG1722	exodeoxyribonuclease VII activity
F3X89_RS02295	COG0123	including yeast histone deacetylase and acetoin utilization protein
F3X89_RS02310	COG1268	BioY protein
F3X89_RS02315	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F3X89_RS02320	COG1122	ATPase activity
F3X89_RS02325	COG3214	Protein conserved in bacteria
F3X89_RS02330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3X89_RS02330	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3X89_RS02335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F3X89_RS02345	COG0406	alpha-ribazole phosphatase activity
F3X89_RS02350	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3X89_RS02355	COG0484	heat shock protein binding
F3X89_RS02365	COG0259	pyridoxamine-phosphate oxidase activity
F3X89_RS02375	COG1686	Belongs to the peptidase S11 family
F3X89_RS02385	COG0312	modulator of DNA gyrase
F3X89_RS02395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3X89_RS02400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3X89_RS02405	COG0109	protoheme IX farnesyltransferase activity
F3X89_RS02415	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
F3X89_RS02425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3X89_RS02430	COG0640	Transcriptional regulator
F3X89_RS02455	COG3346	SURF1 family
F3X89_RS02460	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F3X89_RS02465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F3X89_RS02470	COG0328	RNA-DNA hybrid ribonuclease activity
F3X89_RS02485	COG0803	Belongs to the bacterial solute-binding protein 9 family
F3X89_RS02495	COG1121	(ABC) transporter
F3X89_RS02500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F3X89_RS02500	COG0678	peroxiredoxin activity
F3X89_RS02510	COG1678	Uncharacterized ACR, COG1678
F3X89_RS02530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3X89_RS02535	COG0612	Peptidase, M16
F3X89_RS02550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3X89_RS02560	COG1268	BioY protein
F3X89_RS02570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3X89_RS02590	COG2189	Belongs to the N(4) N(6)-methyltransferase family
F3X89_RS02605	COG1194	a g-specific adenine glycosylase
F3X89_RS02615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3X89_RS02620	COG1196	nuclear chromosome segregation
F3X89_RS02625	COG1253	flavin adenine dinucleotide binding
F3X89_RS02640	COG0574	Belongs to the PEP-utilizing enzyme family
F3X89_RS02640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3X89_RS02680	COG0463	Glycosyl transferase, family 2
F3X89_RS02705	COG1956	GAF domain-containing protein
F3X89_RS02715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F3X89_RS02735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F3X89_RS02750	COG0477	Major facilitator Superfamily
F3X89_RS02760	COG2895	sulfate adenylyltransferase (ATP) activity
F3X89_RS02765	COG0175	sulfate reduction
F3X89_RS02770	COG0175	sulfate reduction
F3X89_RS02775	COG1959	2 iron, 2 sulfur cluster binding
F3X89_RS02795	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
F3X89_RS02800	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS02805	COG0625	glutathione transferase activity
F3X89_RS02810	COG1309	transcriptional regulator
F3X89_RS02825	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F3X89_RS02830	COG1063	alcohol dehydrogenase
F3X89_RS02850	COG1349	DNA-binding transcription factor activity
F3X89_RS02860	COG0625	glutathione transferase activity
F3X89_RS02880	COG0583	DNA-binding transcription factor activity
F3X89_RS02895	COG1960	acyl-CoA dehydrogenase activity
F3X89_RS02900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3X89_RS02940	COG1793	dna ligase
F3X89_RS02965	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_RS02970	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_RS02975	COG1846	Transcriptional regulator
F3X89_RS02980	COG1764	response to oxidative stress
F3X89_RS02995	COG1846	Transcriptional regulator
F3X89_RS03010	COG0433	COG0433 Predicted ATPase
F3X89_RS03025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F3X89_RS03030	COG4106	trans-aconitate 2-methyltransferase activity
F3X89_RS03040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3X89_RS03045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3X89_RS03055	COG2814	Major facilitator Superfamily
F3X89_RS03090	COG1278	Cold shock
F3X89_RS03095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3X89_RS03105	COG2207	Transcriptional regulator
F3X89_RS03110	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS03130	COG2010	Cytochrome c
F3X89_RS03165	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F3X89_RS03200	COG0484	heat shock protein binding
F3X89_RS03215	COG2514	catechol 2,3-dioxygenase activity
F3X89_RS03220	COG1272	protein, Hemolysin III
F3X89_RS03235	COG2111	Na H antiporter
F3X89_RS03235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3X89_RS03240	COG2111	Na H antiporter
F3X89_RS03245	COG1006	Multisubunit Na H antiporter MnhC subunit
F3X89_RS03250	COG0651	ATP synthesis coupled electron transport
F3X89_RS03255	COG1863	multisubunit Na H antiporter MnhE subunit
F3X89_RS03260	COG2212	antiporter activity
F3X89_RS03265	COG1320	monovalent cation:proton antiporter activity
F3X89_RS03270	COG4957	zinc ion binding
F3X89_RS03275	COG2166	iron-sulfur cluster assembly
F3X89_RS03285	COG2205	protein histidine kinase activity
F3X89_RS03325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3X89_RS03330	COG2983	Belongs to the UPF0260 family
F3X89_RS03360	COG4235	cytochrome complex assembly
F3X89_RS03365	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F3X89_RS03370	COG1138	Cytochrome C-type biogenesis protein
F3X89_RS03375	COG3088	subunit of a heme lyase
F3X89_RS03380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3X89_RS03385	COG0745	RESPONSE REGULATOR receiver
F3X89_RS03390	COG2205	protein histidine kinase activity
F3X89_RS03395	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F3X89_RS03400	COG2202	Pas domain
F3X89_RS03400	COG2205	protein histidine kinase activity
F3X89_RS03405	COG0308	aminopeptidase N
F3X89_RS03410	COG0840	transmembrane signaling receptor activity
F3X89_RS03410	COG3290	protein histidine kinase activity
F3X89_RS03430	COG1573	uracil-dna glycosylase
F3X89_RS03435	COG0443	Heat shock 70 kDa protein
F3X89_RS03445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS03450	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS03475	COG2239	Acts as a magnesium transporter
F3X89_RS03485	COG1733	regulation of RNA biosynthetic process
F3X89_RS03490	COG2814	Major facilitator Superfamily
F3X89_RS03500	COG0174	glutamine synthetase
F3X89_RS03515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F3X89_RS03520	COG0463	Glycosyl transferase, family 2
F3X89_RS03530	COG4941	Belongs to the sigma-70 factor family
F3X89_RS03540	COG3795	YCII-related domain
F3X89_RS03555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F3X89_RS03580	COG0457	Tetratricopeptide repeat
F3X89_RS03580	COG0705	Rhomboid family
F3X89_RS03585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F3X89_RS03610	COG3718	enzyme involved in inositol metabolism
F3X89_RS03615	COG1082	Xylose isomerase domain protein TIM barrel
F3X89_RS03620	COG3962	Belongs to the TPP enzyme family
F3X89_RS03625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_RS03780	COG0740	serine-type endopeptidase activity
F3X89_RS03890	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F3X89_RS03955	COG0798	PFAM Bile acid sodium symporter
F3X89_RS03965	COG0640	Transcriptional regulator
F3X89_RS03990	COG0741	lytic transglycosylase activity
F3X89_RS03995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_RS04000	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F3X89_RS04010	COG1758	RNA polymerase activity
F3X89_RS04030	COG0736	holo-[acyl-carrier-protein] synthase activity
F3X89_RS04035	COG0681	Belongs to the peptidase S26 family
F3X89_RS04040	COG0571	ribonuclease III activity
F3X89_RS04045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F3X89_RS04055	COG1381	Involved in DNA repair and RecF pathway recombination
F3X89_RS04065	COG1418	mRNA catabolic process
F3X89_RS04080	COG2032	superoxide dismutase activity
F3X89_RS04095	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F3X89_RS04100	COG0354	folic acid binding
F3X89_RS04125	COG1742	UPF0060 membrane protein
F3X89_RS04140	COG1183	phosphatidylcholine synthase activity
F3X89_RS04145	COG0688	phosphatidylethanolamine metabolic process
F3X89_RS04150	COG0671	phosphoesterase, PA-phosphatase related
F3X89_RS04155	COG5265	(ABC) transporter
F3X89_RS04175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3X89_RS04200	COG0215	cysteine-tRNA ligase activity
F3X89_RS04205	COG4221	oxidoreductase activity
F3X89_RS04210	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F3X89_RS04215	COG1286	toxin biosynthetic process
F3X89_RS04225	COG1280	lysine exporter protein (LysE YggA)
F3X89_RS04230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3X89_RS04235	COG0305	Participates in initiation and elongation during chromosome replication
F3X89_RS04255	COG0359	binds to the 23S rRNA
F3X89_RS04265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F3X89_RS04270	COG0360	Binds together with S18 to 16S ribosomal RNA
F3X89_RS04290	COG0667	Aldo Keto reductase
F3X89_RS04295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F3X89_RS04305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3X89_RS04310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3X89_RS04315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F3X89_RS04320	COG1561	YicC-like family, N-terminal region
F3X89_RS04325	COG0194	GDP metabolic process
F3X89_RS04330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F3X89_RS04335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F3X89_RS04345	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F3X89_RS04360	COG0671	phosphoesterase, PA-phosphatase related
F3X89_RS04365	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F3X89_RS04375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F3X89_RS04390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3X89_RS04390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F3X89_RS04395	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F3X89_RS04400	COG1505	serine-type exopeptidase activity
F3X89_RS04410	COG0488	(ABC) transporter
F3X89_RS04425	COG0105	UTP biosynthetic process
F3X89_RS04445	COG0314	molybdopterin synthase activity
F3X89_RS04455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3X89_RS04460	COG0322	excinuclease ABC activity
F3X89_RS04465	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS04475	COG0625	glutathione transferase activity
F3X89_RS04480	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F3X89_RS04485	COG0243	molybdopterin cofactor binding
F3X89_RS04495	COG3454	Phosphonate metabolism
F3X89_RS04500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F3X89_RS04505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F3X89_RS04510	COG0628	permease
F3X89_RS04520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F3X89_RS04525	COG0248	Ppx GppA phosphatase
F3X89_RS04535	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3X89_RS04540	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F3X89_RS04545	COG2132	Multicopper oxidase
F3X89_RS04555	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F3X89_RS04575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3X89_RS04580	COG3654	unkown
F3X89_RS04595	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
F3X89_RS04605	COG0113	porphobilinogen synthase activity
F3X89_RS04625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F3X89_RS04630	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F3X89_RS04635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3X89_RS04635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3X89_RS04645	COG0454	-acetyltransferase
F3X89_RS04660	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F3X89_RS04665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F3X89_RS04670	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
F3X89_RS04690	COG0416	fatty acid biosynthetic process
F3X89_RS04695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3X89_RS04700	COG0776	regulation of translation
F3X89_RS04755	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
F3X89_RS04760	COG4423	Transcription factor
F3X89_RS04770	COG0438	transferase activity, transferring glycosyl groups
F3X89_RS04810	COG1612	heme a metabolic process
F3X89_RS04820	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F3X89_RS04825	COG0010	Belongs to the arginase family
F3X89_RS04840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F3X89_RS04845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F3X89_RS04860	COG1832	CoA-binding protein
F3X89_RS04880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F3X89_RS04885	COG0573	inorganic phosphate transmembrane transporter activity
F3X89_RS04895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F3X89_RS04905	COG3706	GGDEF domain
F3X89_RS04910	COG0740	serine-type endopeptidase activity
F3X89_RS04915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F3X89_RS04920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F3X89_RS04925	COG0776	regulation of translation
F3X89_RS04930	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS04935	COG0667	Aldo Keto reductase
F3X89_RS04940	COG0420	3'-5' exonuclease activity
F3X89_RS04945	COG4717	serine-type aminopeptidase activity
F3X89_RS04955	COG1216	Glycosyl transferase, family 2
F3X89_RS04955	COG0438	transferase activity, transferring glycosyl groups
F3X89_RS04980	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3X89_RS04985	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3X89_RS04990	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3X89_RS04995	COG0649	NAD binding
F3X89_RS05005	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F3X89_RS05010	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F3X89_RS05015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F3X89_RS05015	COG3743	rRNA binding
F3X89_RS05025	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
F3X89_RS05030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3X89_RS05040	COG0713	ATP synthesis coupled electron transport
F3X89_RS05055	COG1007	ATP synthesis coupled electron transport
F3X89_RS05070	COG0346	lactoylglutathione lyase activity
F3X89_RS05080	COG0442	prolyl-tRNA aminoacylation
F3X89_RS05090	COG1136	(ABC) transporter
F3X89_RS05120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3X89_RS05140	COG0784	Response regulator, receiver
F3X89_RS05150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F3X89_RS05155	COG2814	Major facilitator Superfamily
F3X89_RS05170	COG0557	exoribonuclease II activity
F3X89_RS05175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3X89_RS05180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F3X89_RS05180	COG0758	DNA mediated transformation
F3X89_RS05185	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
F3X89_RS05195	COG0540	Belongs to the ATCase OTCase family
F3X89_RS05200	COG1960	acyl-CoA dehydrogenase activity
F3X89_RS05205	COG3609	addiction module antidote protein, CC2985 family
F3X89_RS05215	COG0456	acetyltransferase
F3X89_RS05235	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F3X89_RS05240	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F3X89_RS05245	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F3X89_RS05250	COG0154	amidase activity
F3X89_RS05265	COG3811	Belongs to the UPF0386 family
F3X89_RS05275	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F3X89_RS05295	COG4765	Protein conserved in bacteria
F3X89_RS05310	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F3X89_RS05325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F3X89_RS05335	COG0436	Aminotransferase
F3X89_RS05340	COG1530	ribonuclease E activity
F3X89_RS05345	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3X89_RS05350	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3X89_RS05360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F3X89_RS05390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3X89_RS05410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F3X89_RS05415	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F3X89_RS05440	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3X89_RS05450	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F3X89_RS05455	COG0081	regulation of translation
F3X89_RS05460	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F3X89_RS05465	COG0222	ribosome binding
F3X89_RS05470	COG0085	RNA polymerase activity
F3X89_RS05475	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F3X89_RS05485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F3X89_RS05490	COG0049	tRNA binding
F3X89_RS05495	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F3X89_RS05500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F3X89_RS05505	COG0051	transcription antitermination factor activity, RNA binding
F3X89_RS05510	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F3X89_RS05515	COG0088	Forms part of the polypeptide exit tunnel
F3X89_RS05520	COG0089	rRNA binding
F3X89_RS05525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F3X89_RS05530	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F3X89_RS05535	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F3X89_RS05540	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F3X89_RS05545	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F3X89_RS05550	COG0255	Belongs to the universal ribosomal protein uL29 family
F3X89_RS05555	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F3X89_RS05560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
F3X89_RS05565	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F3X89_RS05570	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F3X89_RS05575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F3X89_RS05580	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F3X89_RS05585	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F3X89_RS05590	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F3X89_RS05595	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F3X89_RS05600	COG1841	ribosomal large subunit assembly
F3X89_RS05605	COG0200	Binds to the 23S rRNA
F3X89_RS05610	COG0201	protein transport
F3X89_RS05615	COG0563	adenylate kinase activity
F3X89_RS05620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F3X89_RS05625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F3X89_RS05630	COG0202	RNA polymerase activity
F3X89_RS05635	COG0203	ribosomal protein L17
F3X89_RS05640	COG3739	integral membrane protein
F3X89_RS05655	COG1289	transmembrane transporter activity
F3X89_RS05665	COG1566	PFAM secretion protein HlyD family protein
F3X89_RS05670	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
F3X89_RS05675	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F3X89_RS05680	COG0129	dihydroxy-acid dehydratase activity
F3X89_RS05695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F3X89_RS05715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_RS05735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F3X89_RS05760	COG0488	(ABC) transporter
F3X89_RS05765	COG1253	flavin adenine dinucleotide binding
F3X89_RS05790	COG0789	Transcriptional regulator
F3X89_RS05805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3X89_RS05815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3X89_RS05820	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
F3X89_RS05830	COG1546	Belongs to the CinA family
F3X89_RS05830	COG1058	Belongs to the CinA family
F3X89_RS05835	COG0655	NAD(P)H dehydrogenase (quinone) activity
F3X89_RS05845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F3X89_RS05860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3X89_RS05875	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS05885	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F3X89_RS05890	COG0583	DNA-binding transcription factor activity
F3X89_RS05895	COG0737	Belongs to the 5'-nucleotidase family
F3X89_RS05910	COG1522	sequence-specific DNA binding
F3X89_RS05915	COG0686	Belongs to the AlaDH PNT family
F3X89_RS05930	COG2897	thiosulfate sulfurtransferase activity
F3X89_RS05935	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F3X89_RS05940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3X89_RS05945	COG0300	oxidoreductase activity
F3X89_RS05950	COG3842	ATPase activity
F3X89_RS05955	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
F3X89_RS05960	COG0395	ABC-type sugar transport system, permease component
F3X89_RS05965	COG1175	transmembrane transport
F3X89_RS05970	COG1653	transport
F3X89_RS06025	COG2755	lipolytic protein G-D-S-L family
F3X89_RS06025	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3X89_RS06030	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F3X89_RS06040	COG0525	valine-tRNA ligase activity
F3X89_RS06060	COG0316	Belongs to the HesB IscA family
F3X89_RS06065	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F3X89_RS06070	COG0018	arginyl-trna synthetase
F3X89_RS06080	COG1472	Belongs to the glycosyl hydrolase 3 family
F3X89_RS06085	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F3X89_RS06095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3X89_RS06100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3X89_RS06105	COG0805	protein transport
F3X89_RS06110	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F3X89_RS06115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F3X89_RS06120	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F3X89_RS06125	COG0739	heme binding
F3X89_RS06135	COG1862	Preprotein translocase
F3X89_RS06160	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
F3X89_RS06190	COG0544	peptidyl-prolyl cis-trans isomerase activity
F3X89_RS06210	COG2003	Belongs to the UPF0758 family
F3X89_RS06215	COG0024	Methionine aminopeptidase
F3X89_RS06220	COG1489	DNA binding
F3X89_RS06225	COG3243	poly(R)-hydroxyalkanoic acid synthase
F3X89_RS06235	COG0436	Aminotransferase
F3X89_RS06310	COG1278	Cold shock
F3X89_RS06345	COG1280	lysine exporter protein (LysE YggA)
F3X89_RS06350	COG1522	sequence-specific DNA binding
F3X89_RS06360	COG1126	abc transporter atp-binding protein
F3X89_RS06365	COG0765	amino acid transport
F3X89_RS06370	COG4597	amino acid ABC transporter
F3X89_RS06375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_RS06380	COG0626	cystathionine gamma-synthase activity
F3X89_RS06395	COG0596	Alpha beta hydrolase
F3X89_RS06420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F3X89_RS06430	COG0537	adenosine 5'-monophosphoramidase activity
F3X89_RS06455	COG0052	Belongs to the universal ribosomal protein uS2 family
F3X89_RS06460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F3X89_RS06465	COG0528	UMP kinase activity
F3X89_RS06470	COG0233	cytoplasmic translational termination
F3X89_RS06475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F3X89_RS06485	COG0750	zinc metalloprotease
F3X89_RS06490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3X89_RS06495	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3X89_RS06500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F3X89_RS06505	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3X89_RS06510	COG3494	Protein of unknown function (DUF1009)
F3X89_RS06515	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3X89_RS06530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F3X89_RS06540	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F3X89_RS06545	COG0148	phosphopyruvate hydratase activity
F3X89_RS06555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F3X89_RS06560	COG0022	dehydrogenase e1 component
F3X89_RS06560	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3X89_RS06565	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3X89_RS06575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3X89_RS06590	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F3X89_RS06605	COG2867	negative regulation of translational initiation
F3X89_RS06610	COG1546	Belongs to the CinA family
F3X89_RS06615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
F3X89_RS06615	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
F3X89_RS06625	COG3852	Histidine kinase
F3X89_RS06630	COG2204	response regulator
F3X89_RS06635	COG5000	phosphorelay sensor kinase activity
F3X89_RS06640	COG2204	response regulator
F3X89_RS06645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3X89_RS06650	COG1923	regulation of RNA biosynthetic process
F3X89_RS06655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F3X89_RS06660	COG3956	TIGRFAM MazG family protein
F3X89_RS06680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3X89_RS06725	COG0785	Cytochrome C biogenesis protein
F3X89_RS06730	COG0679	Auxin Efflux Carrier
F3X89_RS06735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3X89_RS06740	COG1183	phosphatidylcholine synthase activity
F3X89_RS06750	COG3845	ABC transporter
F3X89_RS06755	COG4603	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS06760	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS06770	COG1879	ABC-type sugar transport system periplasmic component
F3X89_RS06775	COG1129	ABC transporter
F3X89_RS06780	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS06785	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS06790	COG2186	Transcriptional regulator
F3X89_RS06795	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F3X89_RS06800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F3X89_RS06820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F3X89_RS06830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F3X89_RS06845	COG0583	DNA-binding transcription factor activity
F3X89_RS06870	COG0174	glutamine synthetase
F3X89_RS06875	COG0347	Belongs to the P(II) protein family
F3X89_RS06880	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F3X89_RS06880	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F3X89_RS06890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F3X89_RS06895	COG0629	single-stranded DNA binding
F3X89_RS06900	COG2095	MarC family integral membrane protein
F3X89_RS06905	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3X89_RS06930	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F3X89_RS06945	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F3X89_RS06950	COG0343	queuine tRNA-ribosyltransferase activity
F3X89_RS06975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3X89_RS06990	COG1132	(ABC) transporter
F3X89_RS06995	COG1132	(ABC) transporter
F3X89_RS07000	COG0583	DNA-binding transcription factor activity
F3X89_RS07025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F3X89_RS07025	COG0321	lipoyl(octanoyl) transferase activity
F3X89_RS07030	COG0084	hydrolase, TatD family'
F3X89_RS07035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3X89_RS07040	COG0730	response to heat
F3X89_RS07050	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F3X89_RS07080	COG2094	Belongs to the DNA glycosylase MPG family
F3X89_RS07110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F3X89_RS07115	COG0134	indole-3-glycerol-phosphate synthase activity
F3X89_RS07120	COG0315	cyclic pyranopterin monophosphate synthase activity
F3X89_RS07130	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
F3X89_RS07140	COG0372	Belongs to the citrate synthase family
F3X89_RS07145	COG0372	Belongs to the citrate synthase family
F3X89_RS07150	COG0583	DNA-binding transcription factor activity
F3X89_RS07170	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
F3X89_RS07185	COG0504	CTP synthase activity
F3X89_RS07190	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3X89_RS07195	COG0149	triose-phosphate isomerase activity
F3X89_RS07205	COG0187	DNA topoisomerase II activity
F3X89_RS07215	COG0628	permease
F3X89_RS07250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F3X89_RS07260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F3X89_RS07270	COG0302	gtp cyclohydrolase
F3X89_RS07275	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F3X89_RS07280	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3X89_RS07305	COG2267	carboxylic ester hydrolase activity
F3X89_RS07320	COG1686	Belongs to the peptidase S11 family
F3X89_RS07340	COG1760	l-serine dehydratase
F3X89_RS07365	COG2239	Acts as a magnesium transporter
F3X89_RS07370	COG0242	peptide deformylase activity
F3X89_RS07385	COG0321	lipoyl(octanoyl) transferase activity
F3X89_RS07400	COG4770	biotin carboxylase activity
F3X89_RS07405	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F3X89_RS07410	COG1671	Belongs to the UPF0178 family
F3X89_RS07415	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
F3X89_RS07425	COG2259	Doxx family
F3X89_RS07430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3X89_RS07445	COG0546	phosphoglycolate phosphatase activity
F3X89_RS07465	COG0509	glycine decarboxylation via glycine cleavage system
F3X89_RS07470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F3X89_RS07470	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F3X89_RS07480	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3X89_RS07495	COG0316	Belongs to the HesB IscA family
F3X89_RS07500	COG2151	metal-sulfur cluster biosynthetic enzyme
F3X89_RS07505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F3X89_RS07510	COG0719	Fe-S assembly protein
F3X89_RS07515	COG0396	ATPase activity
F3X89_RS07525	COG0719	Fe-S assembly protein
F3X89_RS07535	COG2945	thiolester hydrolase activity
F3X89_RS07550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F3X89_RS07565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F3X89_RS07570	COG2833	Protein of unknown function (DUF455)
F3X89_RS07575	COG0741	lytic transglycosylase activity
F3X89_RS07575	COG0739	heme binding
F3X89_RS07575	COG1196	nuclear chromosome segregation
F3X89_RS07580	COG0513	Belongs to the DEAD box helicase family
F3X89_RS07585	COG1051	belongs to the nudix hydrolase family
F3X89_RS07595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F3X89_RS07600	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F3X89_RS07600	COG3608	succinylglutamate desuccinylase aspartoacylase
F3X89_RS07615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F3X89_RS07620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3X89_RS07640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F3X89_RS07660	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F3X89_RS07665	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3X89_RS07670	COG0047	phosphoribosylformylglycinamidine synthase activity
F3X89_RS07680	COG1660	Displays ATPase and GTPase activities
F3X89_RS07690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3X89_RS07700	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3X89_RS07725	COG2814	Major facilitator Superfamily
F3X89_RS07730	COG2814	Major facilitator Superfamily
F3X89_RS07740	COG0483	inositol monophosphate 1-phosphatase activity
F3X89_RS07745	COG0483	inositol monophosphate 1-phosphatase activity
F3X89_RS07750	COG0037	tRNA processing
F3X89_RS07755	COG2066	Belongs to the glutaminase family
F3X89_RS07760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F3X89_RS07770	COG1304	FMN binding
F3X89_RS07780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F3X89_RS07795	COG0538	isocitrate dehydrogenase activity
F3X89_RS07810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F3X89_RS07815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F3X89_RS07825	COG2313	pseudouridylate synthase activity
F3X89_RS07860	COG3106	COG3106 Predicted ATPase
F3X89_RS07865	COG3768	UPF0283 membrane protein
F3X89_RS07885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F3X89_RS07895	COG0633	Ferredoxin
F3X89_RS07925	COG3507	Belongs to the glycosyl hydrolase 43 family
F3X89_RS07930	COG0667	Aldo Keto reductase
F3X89_RS07935	COG0673	inositol 2-dehydrogenase activity
F3X89_RS07955	COG0395	ABC-type sugar transport system, permease component
F3X89_RS07960	COG1175	transmembrane transport
F3X89_RS07975	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F3X89_RS07985	COG0456	acetyltransferase
F3X89_RS08000	COG1127	ABC transporter
F3X89_RS08005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F3X89_RS08010	COG2814	Major facilitator Superfamily
F3X89_RS08025	COG0280	phosphate acetyltransferase
F3X89_RS08025	COG0281	malic enzyme
F3X89_RS08040	COG0823	Involved in the tonB-independent uptake of proteins
F3X89_RS08050	COG1368	sulfuric ester hydrolase activity
F3X89_RS08075	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
F3X89_RS08090	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F3X89_RS08095	COG0546	phosphoglycolate phosphatase activity
F3X89_RS08100	COG2989	Protein conserved in bacteria
F3X89_RS08105	COG0114	fumarate hydratase activity
F3X89_RS08115	COG3706	GGDEF domain
F3X89_RS08130	COG1846	Transcriptional regulator
F3X89_RS08145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F3X89_RS08155	COG0840	transmembrane signaling receptor activity
F3X89_RS08155	COG2972	Histidine kinase
F3X89_RS08160	COG0697	spore germination
F3X89_RS08165	COG0746	molybdenum cofactor guanylyltransferase activity
F3X89_RS08170	COG1763	Mo-molybdopterin cofactor biosynthetic process
F3X89_RS08180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_RS08195	COG5425	PFAM Usg family protein
F3X89_RS08210	COG0640	Transcriptional regulator
F3X89_RS08220	COG1116	anion transmembrane transporter activity
F3X89_RS08225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS08230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS08235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_RS08240	COG2084	Dehydrogenase
F3X89_RS08245	COG1522	sequence-specific DNA binding
F3X89_RS08250	COG1573	uracil-dna glycosylase
F3X89_RS08260	COG2202	Pas domain
F3X89_RS08260	COG2205	protein histidine kinase activity
F3X89_RS08270	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F3X89_RS08275	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
F3X89_RS08290	COG0697	spore germination
F3X89_RS08305	COG0842	Transport permease protein
F3X89_RS08310	COG1131	(ABC) transporter
F3X89_RS08325	COG1607	acyl-coa hydrolase
F3X89_RS08355	COG2814	Major facilitator Superfamily
F3X89_RS08360	COG0556	nucleotide-excision repair
F3X89_RS08375	COG1278	Cold shock
F3X89_RS08380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3X89_RS08385	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3X89_RS08400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3X89_RS08405	COG1121	(ABC) transporter
F3X89_RS08415	COG0523	cobalamin synthesis protein
F3X89_RS08440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3X89_RS08455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3X89_RS08515	COG1917	Cupin 2, conserved barrel domain protein
F3X89_RS08540	COG1492	cobalamin metabolic process
F3X89_RS08555	COG4176	ABC-type proline glycine betaine transport system permease component
F3X89_RS08560	COG4175	Glycine betaine
F3X89_RS08560	COG0517	IMP dehydrogenase activity
F3X89_RS08565	COG0646	methionine synthase
F3X89_RS08565	COG1410	methionine synthase
F3X89_RS08575	COG0463	Glycosyl transferase, family 2
F3X89_RS08590	COG5598	trimethylamine methyltransferase
F3X89_RS08595	COG5012	cobalamin binding
F3X89_RS08625	COG0646	methionine synthase
F3X89_RS08625	COG1410	methionine synthase
F3X89_RS08645	COG0583	DNA-binding transcription factor activity
F3X89_RS08670	COG0745	RESPONSE REGULATOR receiver
F3X89_RS08675	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
F3X89_RS08675	COG3264	Mechanosensitive ion channel
F3X89_RS08700	COG1959	2 iron, 2 sulfur cluster binding
F3X89_RS08715	COG0384	phenazine biosynthesis protein PhzF
F3X89_RS08730	COG3842	ATPase activity
F3X89_RS08745	COG0667	Aldo Keto reductase
F3X89_RS08750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3X89_RS08765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3X89_RS08775	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F3X89_RS08785	COG2207	Transcriptional regulator
F3X89_RS08790	COG1064	alcohol dehydrogenase
F3X89_RS08795	COG1252	NADH dehydrogenase
F3X89_RS08805	COG1522	sequence-specific DNA binding
F3X89_RS08810	COG1794	racemase activity, acting on amino acids and derivatives
F3X89_RS08820	COG0456	acetyltransferase
F3X89_RS08830	COG2814	Major facilitator Superfamily
F3X89_RS08835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3X89_RS08840	COG1733	regulation of RNA biosynthetic process
F3X89_RS08850	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F3X89_RS08855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3X89_RS08890	COG0656	L-ascorbic acid biosynthetic process
F3X89_RS08900	COG0440	acetolactate synthase activity
F3X89_RS08905	COG0028	Belongs to the TPP enzyme family
F3X89_RS08915	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F3X89_RS08920	COG0560	Phosphoserine phosphatase
F3X89_RS08930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3X89_RS08940	COG0330	HflC and HflK could
F3X89_RS08955	COG0463	Glycosyl transferase, family 2
F3X89_RS08965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3X89_RS08975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F3X89_RS08995	COG0410	ABC transporter
F3X89_RS09010	COG0583	DNA-binding transcription factor activity
F3X89_RS09025	COG3238	Protein conserved in bacteria
F3X89_RS09035	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F3X89_RS09065	COG0277	FAD linked oxidase domain protein
F3X89_RS09070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_RS09075	COG0765	amino acid transport
F3X89_RS09080	COG0765	amino acid transport
F3X89_RS09100	COG2885	chlorophyll binding
F3X89_RS09105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3X89_RS09110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3X89_RS09115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS09120	COG0210	DNA helicase
F3X89_RS09135	COG1335	isochorismatase
F3X89_RS09150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F3X89_RS09155	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F3X89_RS09175	COG0006	proline dipeptidase activity
F3X89_RS09185	COG2264	protein methyltransferase activity
F3X89_RS09195	COG1999	signal sequence binding
F3X89_RS09200	COG0835	chemotaxis
F3X89_RS09215	COG1247	-acetyltransferase
F3X89_RS09220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F3X89_RS09230	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3X89_RS09240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3X89_RS09245	COG0849	cell division
F3X89_RS09250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F3X89_RS09255	COG1181	Belongs to the D-alanine--D-alanine ligase family
F3X89_RS09260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F3X89_RS09265	COG0477	Major facilitator Superfamily
F3X89_RS09270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F3X89_RS09275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F3X89_RS09280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F3X89_RS09290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F3X89_RS09295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F3X89_RS09305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F3X89_RS09320	COG0275	rRNA processing
F3X89_RS09325	COG2001	Belongs to the MraZ family
F3X89_RS09345	COG3023	N-Acetylmuramoyl-L-alanine amidase
F3X89_RS09360	COG1280	lysine exporter protein (LysE YggA)
F3X89_RS09380	COG4106	trans-aconitate 2-methyltransferase activity
F3X89_RS09395	COG0697	spore germination
F3X89_RS09405	COG2226	methyltransferase
F3X89_RS09430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F3X89_RS09435	COG0028	Belongs to the TPP enzyme family
F3X89_RS09440	COG0251	oxidation-reduction process
F3X89_RS09455	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_RS09465	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS09470	COG0174	glutamine synthetase
F3X89_RS09500	COG2011	ABC-type metal ion transport system permease component
F3X89_RS09505	COG3842	ATPase activity
F3X89_RS09510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F3X89_RS09520	COG1609	Transcriptional regulator
F3X89_RS09530	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F3X89_RS09540	COG0673	inositol 2-dehydrogenase activity
F3X89_RS09545	COG0395	ABC-type sugar transport system, permease component
F3X89_RS09550	COG1175	transmembrane transport
F3X89_RS09560	COG2971	BadF BadG BcrA BcrD
F3X89_RS09565	COG2188	Transcriptional regulator
F3X89_RS09580	COG4702	Belongs to the UPF0303 family
F3X89_RS09595	COG0438	transferase activity, transferring glycosyl groups
F3X89_RS09650	COG2264	protein methyltransferase activity
F3X89_RS09705	COG2968	Membrane
F3X89_RS09720	COG0432	Pfam Uncharacterised protein family UPF0047
F3X89_RS09725	COG5507	3-demethylubiquinone-9 3-methyltransferase
F3X89_RS09745	COG0072	phenylalanine-tRNA ligase activity
F3X89_RS09745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3X89_RS09750	COG2207	Transcriptional regulator
F3X89_RS09750	COG1917	Cupin 2, conserved barrel domain protein
F3X89_RS09770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3X89_RS09775	COG1063	alcohol dehydrogenase
F3X89_RS09785	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS09790	COG0514	ATP-dependent DNA helicase (RecQ)
F3X89_RS09795	COG0358	DNA primase activity
F3X89_RS09810	COG0505	Belongs to the CarA family
F3X89_RS09820	COG0534	Mate efflux family protein
F3X89_RS09830	COG2321	neutral zinc metallopeptidase
F3X89_RS09845	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F3X89_RS09850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3X89_RS09870	COG1522	sequence-specific DNA binding
F3X89_RS09875	COG0492	ferredoxin-NADP+ reductase activity
F3X89_RS09880	COG0583	DNA-binding transcription factor activity
F3X89_RS09890	COG1902	pentaerythritol trinitrate reductase activity
F3X89_RS09900	COG0300	oxidoreductase activity
F3X89_RS09905	COG0583	DNA-binding transcription factor activity
F3X89_RS09915	COG0387	Pfam Sodium calcium exchanger
F3X89_RS09925	COG2133	pyrroloquinoline quinone binding
F3X89_RS09935	COG1278	Cold shock
F3X89_RS09945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3X89_RS09960	COG1846	Transcriptional regulator
F3X89_RS09965	COG0745	RESPONSE REGULATOR receiver
F3X89_RS09970	COG2205	protein histidine kinase activity
F3X89_RS09980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3X89_RS10000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
F3X89_RS10010	COG1496	oxidoreductase activity
F3X89_RS10025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F3X89_RS10045	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F3X89_RS10060	COG0193	aminoacyl-tRNA hydrolase activity
F3X89_RS10070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F3X89_RS10090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F3X89_RS10095	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F3X89_RS10095	COG2857	Cytochrome c1
F3X89_RS10115	COG1132	(ABC) transporter
F3X89_RS10120	COG1132	(ABC) transporter
F3X89_RS10125	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F3X89_RS10145	COG0408	coproporphyrinogen oxidase activity
F3X89_RS10160	COG0617	tRNA 3'-terminal CCA addition
F3X89_RS10175	COG0714	Associated with various cellular activities
F3X89_RS10195	COG0454	-acetyltransferase
F3X89_RS10210	COG0435	Glutathione S-transferase
F3X89_RS10250	COG1132	(ABC) transporter
F3X89_RS10255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3X89_RS10260	COG3135	benzoate transporter
F3X89_RS10265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3X89_RS10275	COG0740	serine-type endopeptidase activity
F3X89_RS10285	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F3X89_RS10290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F3X89_RS10295	COG0778	Nitroreductase
F3X89_RS10305	COG0512	Glutamine amidotransferase of anthranilate synthase
F3X89_RS10305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3X89_RS10310	COG0488	(ABC) transporter
F3X89_RS10325	COG2759	Belongs to the formate--tetrahydrofolate ligase family
F3X89_RS10330	COG2862	Uncharacterized protein family, UPF0114
F3X89_RS10345	COG2197	response regulator
F3X89_RS10370	COG1435	thymidine kinase activity
F3X89_RS10380	COG4176	ABC-type proline glycine betaine transport system permease component
F3X89_RS10385	COG4175	Glycine betaine
F3X89_RS10400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3X89_RS10405	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3X89_RS10410	COG0366	Alpha amylase catalytic
F3X89_RS10420	COG0601	transmembrane transport
F3X89_RS10425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS10435	COG4608	Belongs to the ABC transporter superfamily
F3X89_RS10440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_RS10460	COG1846	Transcriptional regulator
F3X89_RS10465	COG1160	GTP binding
F3X89_RS10485	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F3X89_RS10495	COG0024	Methionine aminopeptidase
F3X89_RS10515	COG4941	Belongs to the sigma-70 factor family
F3X89_RS10520	COG3795	YCII-related domain
F3X89_RS10530	COG1619	proteins homologs of microcin C7 resistance protein MccF
F3X89_RS10540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F3X89_RS10545	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS10555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3X89_RS10565	COG0583	DNA-binding transcription factor activity
F3X89_RS10580	COG0402	S-adenosylhomocysteine deaminase activity
F3X89_RS10595	COG2351	hydroxyisourate hydrolase activity
F3X89_RS10600	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
F3X89_RS10610	COG3648	Uricase
F3X89_RS10610	COG3195	allantoin biosynthetic process
F3X89_RS10620	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3X89_RS10625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS10630	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F3X89_RS10630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS10635	COG2205	protein histidine kinase activity
F3X89_RS10635	COG5002	protein histidine kinase activity
F3X89_RS10635	COG0784	Response regulator, receiver
F3X89_RS10640	COG5598	trimethylamine methyltransferase
F3X89_RS10650	COG0513	Belongs to the DEAD box helicase family
F3X89_RS10665	COG2308	Evidence 4 Homologs of previously reported genes of
F3X89_RS10685	COG1132	(ABC) transporter
F3X89_RS10690	COG0129	dihydroxy-acid dehydratase activity
F3X89_RS10695	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS10705	COG4214	carbohydrate transport
F3X89_RS10735	COG0673	inositol 2-dehydrogenase activity
F3X89_RS10745	COG4213	ABC transporter substrate-binding protein
F3X89_RS10750	COG4214	carbohydrate transport
F3X89_RS10755	COG1129	ABC transporter
F3X89_RS10800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F3X89_RS10820	COG0671	phosphoesterase, PA-phosphatase related
F3X89_RS10830	COG2194	sulfuric ester hydrolase activity
F3X89_RS10855	COG0406	alpha-ribazole phosphatase activity
F3X89_RS10900	COG0022	dehydrogenase e1 component
F3X89_RS10910	COG0038	chloride channel
F3X89_RS10930	COG2076	Multidrug Resistance protein
F3X89_RS10940	COG3842	ATPase activity
F3X89_RS10945	COG3833	ABC-type maltose transport systems, permease component
F3X89_RS10965	COG0673	inositol 2-dehydrogenase activity
F3X89_RS11020	COG4558	Periplasmic binding protein
F3X89_RS11025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3X89_RS11030	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F3X89_RS11055	COG0784	Response regulator, receiver
F3X89_RS11060	COG3920	Histidine kinase
F3X89_RS11060	COG2202	Pas domain
F3X89_RS11065	COG0493	'glutamate synthase
F3X89_RS11075	COG1309	transcriptional regulator
F3X89_RS11105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS11110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS11115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_RS11120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS11130	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F3X89_RS11135	COG0830	nickel cation binding
F3X89_RS11140	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
F3X89_RS11145	COG3706	GGDEF domain
F3X89_RS11155	COG0804	urea catabolic process
F3X89_RS11160	COG1442	glycosyl transferase family 8
F3X89_RS11165	COG0832	Belongs to the urease beta subunit family
F3X89_RS11170	COG0831	urea catabolic process
F3X89_RS11175	COG0829	nickel cation binding
F3X89_RS11185	COG0411	ABC transporter
F3X89_RS11205	COG0784	Response regulator, receiver
F3X89_RS11205	COG2198	Histidine kinase
F3X89_RS11205	COG5002	protein histidine kinase activity
F3X89_RS11210	COG0745	RESPONSE REGULATOR receiver
F3X89_RS11215	COG0683	leucine binding
F3X89_RS11250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3X89_RS11255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3X89_RS11255	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3X89_RS11260	COG4311	Sarcosine oxidase, delta subunit
F3X89_RS11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS11325	COG0564	pseudouridine synthase activity
F3X89_RS11330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3X89_RS11340	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F3X89_RS11350	COG0402	S-adenosylhomocysteine deaminase activity
F3X89_RS11355	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F3X89_RS11360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3X89_RS11365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3X89_RS11380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_RS11390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS11395	COG0402	S-adenosylhomocysteine deaminase activity
F3X89_RS11405	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3X89_RS11425	COG0346	lactoylglutathione lyase activity
F3X89_RS11430	COG0251	oxidation-reduction process
F3X89_RS11455	COG0346	lactoylglutathione lyase activity
F3X89_RS11460	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F3X89_RS11465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3X89_RS11480	COG1349	DNA-binding transcription factor activity
F3X89_RS11485	COG0583	DNA-binding transcription factor activity
F3X89_RS11490	COG2855	membrane
F3X89_RS11495	COG5001	Diguanylate cyclase
F3X89_RS11495	COG3300	MHYT domain
F3X89_RS11500	COG0129	dihydroxy-acid dehydratase activity
F3X89_RS11505	COG2084	Dehydrogenase
F3X89_RS11510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3X89_RS11530	COG0583	DNA-binding transcription factor activity
F3X89_RS11540	COG1595	DNA-templated transcription, initiation
F3X89_RS11550	COG0697	spore germination
F3X89_RS11560	COG1846	Transcriptional regulator
F3X89_RS11580	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3X89_RS11585	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS11590	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS11630	COG0477	Major facilitator Superfamily
F3X89_RS11640	COG1278	Cold shock
F3X89_RS11650	COG0346	lactoylglutathione lyase activity
F3X89_RS11660	COG4948	Mandelate Racemase Muconate Lactonizing
F3X89_RS11695	COG2011	ABC-type metal ion transport system permease component
F3X89_RS11705	COG4521	taurine ABC transporter
F3X89_RS11715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS11720	COG0330	HflC and HflK could
F3X89_RS11725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_RS11735	COG2814	Major facilitator Superfamily
F3X89_RS11770	COG0482	sulfurtransferase activity
F3X89_RS11785	COG4589	Belongs to the CDS family
F3X89_RS11795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_RS11835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3X89_RS11840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3X89_RS11845	COG0037	tRNA processing
F3X89_RS11855	COG2885	chlorophyll binding
F3X89_RS11860	COG0823	Involved in the tonB-independent uptake of proteins
F3X89_RS11885	COG0824	Thioesterase
F3X89_RS11905	COG1268	BioY protein
F3X89_RS11910	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F3X89_RS11915	COG2318	DinB family
F3X89_RS11920	COG0494	nUDIX hydrolase
F3X89_RS11925	COG1408	metallophosphoesterase
F3X89_RS11930	COG2255	four-way junction helicase activity
F3X89_RS11935	COG0632	four-way junction helicase activity
F3X89_RS11950	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
F3X89_RS11955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS11960	COG0217	transcriptional regulatory protein
F3X89_RS11970	COG1692	metallophosphoesterase
F3X89_RS11980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3X89_RS12005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3X89_RS12015	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS12020	COG0300	oxidoreductase activity
F3X89_RS12070	COG0126	phosphoglycerate kinase activity
F3X89_RS12075	COG3588	fructose-bisphosphate aldolase
F3X89_RS12080	COG0384	phenazine biosynthesis protein PhzF
F3X89_RS12110	COG0254	rRNA binding
F3X89_RS12120	COG3422	double-strand break repair
F3X89_RS12145	COG0483	inositol monophosphate 1-phosphatase activity
F3X89_RS12175	COG0640	Transcriptional regulator
F3X89_RS12190	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F3X89_RS12195	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F3X89_RS12200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F3X89_RS12205	COG0457	Tetratricopeptide repeat
F3X89_RS12210	COG0596	Alpha beta hydrolase
F3X89_RS12215	COG0583	DNA-binding transcription factor activity
F3X89_RS12245	COG0469	pyruvate kinase activity
F3X89_RS12265	COG3750	Belongs to the UPF0335 family
F3X89_RS12295	COG2372	response to copper ion
F3X89_RS12300	COG0726	polysaccharide deacetylase
F3X89_RS12320	COG3108	Peptidase M15
F3X89_RS12335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3X89_RS12335	COG0512	Glutamine amidotransferase of anthranilate synthase
F3X89_RS12355	COG5310	Homospermidine synthase
F3X89_RS12370	COG0737	Belongs to the 5'-nucleotidase family
F3X89_RS12375	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F3X89_RS12380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3X89_RS12385	COG0330	HflC and HflK could
F3X89_RS12395	COG0517	IMP dehydrogenase activity
F3X89_RS12395	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F3X89_RS12405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3X89_RS12410	COG2951	lytic endotransglycosylase activity
F3X89_RS12430	COG0069	glutamate synthase activity
F3X89_RS12430	COG0067	glutamate synthase
F3X89_RS12430	COG0070	glutamate synthase
F3X89_RS12450	COG0071	Belongs to the small heat shock protein (HSP20) family
F3X89_RS12460	COG1522	sequence-specific DNA binding
F3X89_RS12465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3X89_RS12520	COG0662	Cupin 2, conserved barrel domain protein
F3X89_RS12520	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
F3X89_RS12530	COG2308	Evidence 4 Homologs of previously reported genes of
F3X89_RS12530	COG2307	Protein conserved in bacteria
F3X89_RS12545	COG0058	SHG alpha-glucan phosphorylase activity
F3X89_RS12550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F3X89_RS12555	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F3X89_RS12560	COG0297	glycogen (starch) synthase activity
F3X89_RS12565	COG0033	Phosphoglucomutase
F3X89_RS12570	COG1523	belongs to the glycosyl hydrolase 13 family
F3X89_RS12585	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3X89_RS12585	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3X89_RS12600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS12610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3X89_RS12620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS12625	COG2202	Pas domain
F3X89_RS12625	COG3920	Histidine kinase
F3X89_RS12650	COG5001	Diguanylate cyclase
F3X89_RS12655	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F3X89_RS12660	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F3X89_RS12665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3X89_RS12670	COG1609	Transcriptional regulator
F3X89_RS12675	COG1846	Transcriptional regulator
F3X89_RS12685	COG0523	cobalamin synthesis protein
F3X89_RS12695	COG1045	serine acetyltransferase
F3X89_RS12720	COG0583	DNA-binding transcription factor activity
F3X89_RS12730	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F3X89_RS12745	COG0800	Aldolase
F3X89_RS12750	COG2954	triphosphatase activity
F3X89_RS12760	COG1054	Belongs to the UPF0176 family
F3X89_RS12770	COG0431	NADPH-dependent FMN reductase
F3X89_RS12785	COG0673	inositol 2-dehydrogenase activity
F3X89_RS12795	COG1879	ABC-type sugar transport system periplasmic component
F3X89_RS12800	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS12810	COG1609	Transcriptional regulator
F3X89_RS12820	COG2115	Belongs to the xylose isomerase family
F3X89_RS12825	COG1070	Carbohydrate kinase
F3X89_RS12830	COG1609	Transcriptional regulator
F3X89_RS12855	COG1253	flavin adenine dinucleotide binding
F3X89_RS12865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F3X89_RS12870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F3X89_RS12875	COG0673	inositol 2-dehydrogenase activity
F3X89_RS12880	COG1082	Xylose isomerase domain protein TIM barrel
F3X89_RS12885	COG1082	Xylose isomerase domain protein TIM barrel
F3X89_RS12905	COG0583	DNA-binding transcription factor activity
F3X89_RS12910	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3X89_RS12915	COG3842	ATPase activity
F3X89_RS12920	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_RS12925	COG1177	transmembrane transport
F3X89_RS12945	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS12965	COG3254	rhamnose metabolic process
F3X89_RS12970	COG4948	Mandelate Racemase Muconate Lactonizing
F3X89_RS12975	COG3842	ATPase activity
F3X89_RS12980	COG0395	ABC-type sugar transport system, permease component
F3X89_RS12985	COG1175	transmembrane transport
F3X89_RS13015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3X89_RS13035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3X89_RS13045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F3X89_RS13065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3X89_RS13080	COG0395	ABC-type sugar transport system, permease component
F3X89_RS13085	COG1175	transmembrane transport
F3X89_RS13095	COG2390	Transcriptional regulator
F3X89_RS13115	COG1940	carbohydrate kinase activity
F3X89_RS13120	COG3142	Participates in the control of copper homeostasis
F3X89_RS13135	COG2719	SpoVR family
F3X89_RS13140	COG2718	Belongs to the UPF0229 family
F3X89_RS13145	COG2766	serine protein kinase
F3X89_RS13160	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F3X89_RS13165	COG0424	maF-like protein
F3X89_RS13170	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F3X89_RS13180	COG5328	Belongs to the UPF0262 family
F3X89_RS13185	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F3X89_RS13195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F3X89_RS13220	COG2514	catechol 2,3-dioxygenase activity
F3X89_RS13225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F3X89_RS13235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS13255	COG1764	response to oxidative stress
F3X89_RS13260	COG2186	Transcriptional regulator
F3X89_RS13265	COG4948	Mandelate Racemase Muconate Lactonizing
F3X89_RS13270	COG0670	Belongs to the BI1 family
F3X89_RS13285	COG3781	membrane
F3X89_RS13290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F3X89_RS13295	COG2900	Belongs to the SlyX family
F3X89_RS13305	COG3842	ATPase activity
F3X89_RS13310	COG1175	transmembrane transport
F3X89_RS13325	COG1609	Transcriptional regulator
F3X89_RS13385	COG1396	sequence-specific DNA binding
F3X89_RS13405	COG1222	aaa ATPase
F3X89_RS13435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F3X89_RS13435	COG0784	Response regulator, receiver
F3X89_RS13470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3X89_RS13475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3X89_RS13490	COG4221	oxidoreductase activity
F3X89_RS13495	COG4191	Histidine kinase
F3X89_RS13500	COG4566	intracellular signal transduction
F3X89_RS13505	COG4566	intracellular signal transduction
F3X89_RS13510	COG4566	intracellular signal transduction
F3X89_RS13515	COG0583	DNA-binding transcription factor activity
F3X89_RS13520	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS13575	COG0542	response to heat
F3X89_RS13585	COG2890	protein-(glutamine-N5) methyltransferase activity
F3X89_RS13590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F3X89_RS13600	COG0527	aspartate kinase activity
F3X89_RS13605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3X89_RS13620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3X89_RS13635	COG2226	methyltransferase
F3X89_RS13650	COG0494	nUDIX hydrolase
F3X89_RS13660	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F3X89_RS13665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3X89_RS13670	COG0653	protein targeting
F3X89_RS13675	COG0583	DNA-binding transcription factor activity
F3X89_RS13680	COG1942	4-Oxalocrotonate Tautomerase
F3X89_RS13685	COG0625	glutathione transferase activity
F3X89_RS13700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3X89_RS13715	COG0681	Belongs to the peptidase S26 family
F3X89_RS13720	COG0667	Aldo Keto reductase
F3X89_RS13725	COG2264	protein methyltransferase activity
F3X89_RS13775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F3X89_RS13780	COG1295	ribonuclease BN
F3X89_RS13785	COG0300	oxidoreductase activity
F3X89_RS13800	COG2086	electron transfer activity
F3X89_RS13810	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3X89_RS13815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3X89_RS13820	COG0165	Argininosuccinate lyase
F3X89_RS13855	COG2884	Cell division ATP-binding protein ftsE
F3X89_RS13875	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F3X89_RS13895	COG0287	Prephenate dehydrogenase
F3X89_RS13900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F3X89_RS13905	COG2226	methyltransferase
F3X89_RS13910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3X89_RS13920	COG2382	esterase
F3X89_RS13935	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F3X89_RS13970	COG4536	flavin adenine dinucleotide binding
F3X89_RS13975	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
F3X89_RS13980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F3X89_RS13990	COG4974	Belongs to the 'phage' integrase family
F3X89_RS13995	COG0825	malonyl-CoA metabolic process
F3X89_RS14000	COG3034	peptidoglycan biosynthetic process
F3X89_RS14010	COG0523	cobalamin synthesis protein
F3X89_RS14015	COG1686	Belongs to the peptidase S11 family
F3X89_RS14020	COG1473	amidohydrolase
F3X89_RS14050	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F3X89_RS14060	COG0156	8-amino-7-oxononanoate synthase activity
F3X89_RS14085	COG0729	surface antigen
F3X89_RS14110	COG0010	Belongs to the arginase family
F3X89_RS14115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3X89_RS14120	COG0835	chemotaxis
F3X89_RS14125	COG2223	nitrite transmembrane transporter activity
F3X89_RS14135	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F3X89_RS14140	COG3383	formate dehydrogenase (NAD+) activity
F3X89_RS14165	COG0640	Transcriptional regulator
F3X89_RS14200	COG4948	Mandelate Racemase Muconate Lactonizing
F3X89_RS14205	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS14210	COG1454	alcohol dehydrogenase
F3X89_RS14220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F3X89_RS14225	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F3X89_RS14230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F3X89_RS14235	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F3X89_RS14240	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F3X89_RS14275	COG4974	Belongs to the 'phage' integrase family
F3X89_RS14290	COG0612	Peptidase, M16
F3X89_RS14300	COG1280	lysine exporter protein (LysE YggA)
F3X89_RS14305	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS14320	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3X89_RS14335	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3X89_RS14340	COG0045	succinate-CoA ligase (ADP-forming) activity
F3X89_RS14345	COG0039	L-malate dehydrogenase activity
F3X89_RS14350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F3X89_RS14385	COG2264	protein methyltransferase activity
F3X89_RS14395	COG2350	Protein conserved in bacteria
F3X89_RS14400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F3X89_RS14405	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F3X89_RS14410	COG0181	hydroxymethylbilane synthase activity
F3X89_RS14455	COG1872	DUF167
F3X89_RS14460	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F3X89_RS14470	COG1217	gtp-binding protein TYPA
F3X89_RS14480	COG0339	signal peptide processing
F3X89_RS14495	COG0137	argininosuccinate synthase activity
F3X89_RS14505	COG1280	lysine exporter protein (LysE YggA)
F3X89_RS14515	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F3X89_RS14530	COG2154	pterin-4-alpha-carbinolamine dehydratase
F3X89_RS14535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F3X89_RS14540	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F3X89_RS14550	COG4181	ATPase activity
F3X89_RS14560	COG0670	Belongs to the BI1 family
F3X89_RS14585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3X89_RS14590	COG4133	protoheme IX ABC transporter activity
F3X89_RS14595	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3X89_RS14600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3X89_RS14620	COG2917	probably involved in intracellular septation
F3X89_RS14625	COG0552	protein localization to endoplasmic reticulum
F3X89_RS14630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F3X89_RS14635	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F3X89_RS14655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F3X89_RS14660	COG1605	Chorismate mutase
F3X89_RS14660	COG0287	Prephenate dehydrogenase
F3X89_RS14665	COG0228	four-way junction DNA binding
F3X89_RS14670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F3X89_RS14675	COG0336	Belongs to the RNA methyltransferase TrmD family
F3X89_RS14705	COG1522	sequence-specific DNA binding
F3X89_RS14715	COG0110	maltose O-acetyltransferase activity
F3X89_RS14720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F3X89_RS14725	COG0335	large ribosomal subunit rRNA binding
F3X89_RS14735	COG0765	amino acid transport
F3X89_RS14740	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F3X89_RS14745	COG0697	spore germination
F3X89_RS14750	COG1846	Transcriptional regulator
F3X89_RS14770	COG0656	L-ascorbic acid biosynthetic process
F3X89_RS14780	COG0745	RESPONSE REGULATOR receiver
F3X89_RS14795	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F3X89_RS14800	COG1674	ftsk spoiiie
F3X89_RS14805	COG0004	ammonium transporteR
F3X89_RS14810	COG0347	Belongs to the P(II) protein family
F3X89_RS14815	COG1946	Acyl-CoA thioesterase
F3X89_RS14820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3X89_RS14825	COG1733	regulation of RNA biosynthetic process
F3X89_RS14835	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS14840	COG2835	tetraacyldisaccharide 4'-kinase activity
F3X89_RS14850	COG3118	belongs to the thioredoxin family
F3X89_RS14875	COG0395	ABC-type sugar transport system, permease component
F3X89_RS14880	COG1175	transmembrane transport
F3X89_RS14890	COG3250	beta-galactosidase activity
F3X89_RS14895	COG1609	Transcriptional regulator
F3X89_RS14915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS14925	COG0745	RESPONSE REGULATOR receiver
F3X89_RS14930	COG2205	protein histidine kinase activity
F3X89_RS14980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3X89_RS14985	COG2076	Multidrug Resistance protein
F3X89_RS14995	COG1647	Serine aminopeptidase, S33
F3X89_RS15005	COG2076	Multidrug Resistance protein
F3X89_RS15015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3X89_RS15020	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
F3X89_RS15035	COG3618	amidohydrolase
F3X89_RS15040	COG2814	Major facilitator Superfamily
F3X89_RS15045	COG2188	Transcriptional regulator
F3X89_RS15050	COG0583	DNA-binding transcription factor activity
F3X89_RS15060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3X89_RS15065	COG0697	spore germination
F3X89_RS15075	COG1309	transcriptional regulator
F3X89_RS15095	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F3X89_RS15110	COG0438	transferase activity, transferring glycosyl groups
F3X89_RS15145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS15150	COG1116	anion transmembrane transporter activity
F3X89_RS15155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_RS15165	COG1396	sequence-specific DNA binding
F3X89_RS15200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS15205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3X89_RS15215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3X89_RS15265	COG2814	Major facilitator Superfamily
F3X89_RS15270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F3X89_RS15285	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F3X89_RS15290	COG2986	histidine ammonia-lyase
F3X89_RS15295	COG1228	amidohydrolase
F3X89_RS15300	COG0402	S-adenosylhomocysteine deaminase activity
F3X89_RS15305	COG2188	Transcriptional regulator
F3X89_RS15315	COG2986	histidine ammonia-lyase
F3X89_RS15335	COG0025	NhaP-type Na H and K H
F3X89_RS15365	COG1321	iron dependent repressor
F3X89_RS15370	COG1914	H( )-stimulated, divalent metal cation uptake system
F3X89_RS15375	COG0739	heme binding
F3X89_RS15390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3X89_RS15395	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
F3X89_RS15400	COG2080	2 iron, 2 sulfur cluster binding
F3X89_RS15405	COG1309	transcriptional regulator
F3X89_RS15415	COG3842	ATPase activity
F3X89_RS15420	COG0395	ABC-type sugar transport system, permease component
F3X89_RS15425	COG1175	transmembrane transport
F3X89_RS15465	COG3842	ATPase activity
F3X89_RS15475	COG0395	ABC-type sugar transport system, permease component
F3X89_RS15490	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
F3X89_RS15495	COG2182	Extracellular solute-binding protein
F3X89_RS15510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_RS15520	COG0673	inositol 2-dehydrogenase activity
F3X89_RS15530	COG0673	inositol 2-dehydrogenase activity
F3X89_RS15535	COG1309	transcriptional regulator
F3X89_RS15545	COG1175	transmembrane transport
F3X89_RS15550	COG0395	ABC-type sugar transport system, permease component
F3X89_RS15555	COG0673	inositol 2-dehydrogenase activity
F3X89_RS15560	COG0673	inositol 2-dehydrogenase activity
F3X89_RS15580	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F3X89_RS15590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3X89_RS15595	COG1509	lysine 2,3-aminomutase activity
F3X89_RS15600	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F3X89_RS15605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F3X89_RS15625	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
F3X89_RS15650	COG2188	Transcriptional regulator
F3X89_RS15655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F3X89_RS15660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3X89_RS15675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS15680	COG0488	(ABC) transporter
F3X89_RS15695	COG0477	Major facilitator Superfamily
F3X89_RS15710	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
F3X89_RS15725	COG1329	Transcriptional regulator
F3X89_RS15730	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F3X89_RS15765	COG0183	Belongs to the thiolase family
F3X89_RS15770	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
F3X89_RS15775	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F3X89_RS15785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3X89_RS15790	COG0142	geranyltranstransferase activity
F3X89_RS15800	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
F3X89_RS15805	COG2223	nitrite transmembrane transporter activity
F3X89_RS15810	COG0697	spore germination
F3X89_RS15825	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS15830	COG0583	DNA-binding transcription factor activity
F3X89_RS15835	COG0662	Cupin 2, conserved barrel domain protein
F3X89_RS15850	COG0740	serine-type endopeptidase activity
F3X89_RS15855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_RS15860	COG0765	amino acid transport
F3X89_RS15865	COG1126	abc transporter atp-binding protein
F3X89_RS15875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS15880	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
F3X89_RS15890	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
F3X89_RS15900	COG1132	(ABC) transporter
F3X89_RS15915	COG3459	Glycosyltransferase 36 associated
F3X89_RS15940	COG0444	Belongs to the ABC transporter superfamily
F3X89_RS15945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS15950	COG0601	transmembrane transport
F3X89_RS15965	COG1280	lysine exporter protein (LysE YggA)
F3X89_RS15970	COG4447	cellulose binding
F3X89_RS15970	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
F3X89_RS16015	COG3550	peptidyl-serine autophosphorylation
F3X89_RS16075	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS16080	COG1129	ABC transporter
F3X89_RS16130	COG3038	cytochrome b561
F3X89_RS16145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3X89_RS16155	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
F3X89_RS16160	COG2948	multi-organism process
F3X89_RS16165	COG3504	Conjugal transfer protein
F3X89_RS16170	COG3736	Type IV secretory pathway, component VirB8
F3X89_RS16175	COG3704	protein secretion by the type IV secretion system
F3X89_RS16190	COG3451	type IV secretory pathway VirB4
F3X89_RS16195	COG3702	type iv secretory pathway
F3X89_RS16200	COG3838	Conjugal transfer protein Trbc
F3X89_RS16245	COG1396	sequence-specific DNA binding
F3X89_RS16250	COG1476	TRANSCRIPTIONal
F3X89_RS16255	COG1396	sequence-specific DNA binding
F3X89_RS16295	COG3505	Type IV secretory pathway VirD4
F3X89_RS16300	COG0438	transferase activity, transferring glycosyl groups
F3X89_RS16305	COG0438	transferase activity, transferring glycosyl groups
F3X89_RS16330	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
F3X89_RS16330	COG0662	Cupin 2, conserved barrel domain protein
F3X89_RS16355	COG1216	Glycosyl transferase, family 2
F3X89_RS16355	COG0438	transferase activity, transferring glycosyl groups
F3X89_RS16410	COG3220	belongs to the UPF0276 family
F3X89_RS16450	COG4650	regulator
F3X89_RS16460	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F3X89_RS16465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F3X89_RS16480	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F3X89_RS16485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F3X89_RS16490	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
F3X89_RS16495	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F3X89_RS16500	COG0725	ABC transporter, periplasmic molybdate-binding protein
F3X89_RS16505	COG4149	molybdate abc transporter
F3X89_RS16510	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F3X89_RS16515	COG2005	Transcriptional regulator
F3X89_RS16515	COG3585	molybdate ion transport
F3X89_RS16520	COG0799	negative regulation of ribosome biogenesis
F3X89_RS16525	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F3X89_RS16535	COG0793	Belongs to the peptidase S41A family
F3X89_RS16545	COG0494	nUDIX hydrolase
F3X89_RS16560	COG0587	DNA-directed DNA polymerase activity
F3X89_RS16580	COG2301	Belongs to the HpcH HpaI aldolase family
F3X89_RS16590	COG0066	3-isopropylmalate dehydratase activity
F3X89_RS16600	COG0473	3-isopropylmalate dehydrogenase activity
F3X89_RS16605	COG0671	phosphoesterase, PA-phosphatase related
F3X89_RS16615	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS16620	COG0783	Belongs to the Dps family
F3X89_RS16630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F3X89_RS16640	COG0288	reversible hydration of carbon dioxide
F3X89_RS16650	COG2902	Dehydrogenase
F3X89_RS16655	COG2270	Major facilitator Superfamily
F3X89_RS16660	COG0138	bifunctional purine biosynthesis protein purh
F3X89_RS16670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F3X89_RS16670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F3X89_RS16675	COG0501	Belongs to the peptidase M48B family
F3X89_RS16685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3X89_RS16700	COG0495	leucyl-tRNA aminoacylation
F3X89_RS16725	COG0357	Ribosomal RNA small subunit methyltransferase G
F3X89_RS16730	COG0445	tRNA wobble uridine modification
F3X89_RS16735	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F3X89_RS16740	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F3X89_RS16745	COG1981	membrane
F3X89_RS16750	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F3X89_RS16755	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
F3X89_RS16760	COG0424	maF-like protein
F3X89_RS16765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3X89_RS16770	COG0237	dephospho-CoA kinase activity
F3X89_RS16785	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F3X89_RS16800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F3X89_RS16855	COG0135	phosphoribosylanthranilate isomerase activity
F3X89_RS16860	COG0133	tryptophan synthase activity
F3X89_RS16865	COG0159	tryptophan synthase activity
F3X89_RS16870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F3X89_RS16885	COG1074	ATP-dependent DNA helicase activity
F3X89_RS16895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3X89_RS16900	COG3178	'Phosphotransferase
F3X89_RS16905	COG2205	protein histidine kinase activity
F3X89_RS16910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F3X89_RS16915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3X89_RS16920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3X89_RS16920	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3X89_RS16930	COG0642	Histidine kinase
F3X89_RS16935	COG0745	RESPONSE REGULATOR receiver
F3X89_RS16940	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
F3X89_RS16960	COG1072	(Pantothenic acid kinase))
F3X89_RS16965	COG0140	phosphoribosyl-ATP diphosphatase activity
F3X89_RS16970	COG0107	imidazoleglycerol-phosphate synthase activity
F3X89_RS16975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F3X89_RS16980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F3X89_RS16990	COG0131	Imidazoleglycerol-phosphate dehydratase
F3X89_RS16995	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
F3X89_RS17000	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
F3X89_RS17020	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F3X89_RS17040	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
F3X89_RS17050	COG1643	Atp-dependent helicase
F3X89_RS17055	COG2423	ornithine cyclodeaminase activity
F3X89_RS17165	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS17170	COG0673	inositol 2-dehydrogenase activity
F3X89_RS17175	COG3962	Belongs to the TPP enzyme family
F3X89_RS17195	COG0673	inositol 2-dehydrogenase activity
F3X89_RS17210	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS17215	COG1129	ABC transporter
F3X89_RS17225	COG0673	inositol 2-dehydrogenase activity
F3X89_RS17230	COG1082	Xylose isomerase domain protein TIM barrel
F3X89_RS17260	COG0395	ABC-type sugar transport system, permease component
F3X89_RS17280	COG3622	Belongs to the hyi family
F3X89_RS17285	COG1276	copper resistance
F3X89_RS17290	COG2372	response to copper ion
F3X89_RS17295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F3X89_RS17300	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS17305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3X89_RS17325	COG0539	negative regulation of cytoplasmic translation
F3X89_RS17330	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F3X89_RS17335	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F3X89_RS17350	COG2815	serine threonine protein kinase
F3X89_RS17350	COG0515	serine threonine protein kinase
F3X89_RS17355	COG0631	protein serine/threonine phosphatase activity
F3X89_RS17475	COG2860	membrane
F3X89_RS17485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F3X89_RS17495	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3X89_RS17500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3X89_RS17515	COG1185	polyribonucleotide nucleotidyltransferase activity
F3X89_RS17520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F3X89_RS17525	COG2267	carboxylic ester hydrolase activity
F3X89_RS17530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F3X89_RS17535	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F3X89_RS17540	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F3X89_RS17555	COG0779	Required for maturation of 30S ribosomal subunits
F3X89_RS17560	COG2951	lytic endotransglycosylase activity
F3X89_RS17565	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F3X89_RS17580	COG1522	sequence-specific DNA binding
F3X89_RS17585	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
F3X89_RS17590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F3X89_RS17605	COG2816	NAD+ diphosphatase activity
F3X89_RS17610	COG2378	regulation of single-species biofilm formation
F3X89_RS17625	COG0077	Prephenate dehydratase
F3X89_RS17625	COG1605	Chorismate mutase
F3X89_RS17630	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
F3X89_RS17635	COG3474	cytochrome
F3X89_RS17650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_RS17670	COG2226	methyltransferase
F3X89_RS17685	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F3X89_RS17690	COG0484	heat shock protein binding
F3X89_RS17695	COG0443	Heat shock 70 kDa protein
F3X89_RS17700	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3X89_RS17725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F3X89_RS17735	COG1187	pseudouridine synthase activity
F3X89_RS17745	COG2205	protein histidine kinase activity
F3X89_RS17785	COG2972	Histidine kinase
F3X89_RS17785	COG0840	transmembrane signaling receptor activity
F3X89_RS17790	COG3842	ATPase activity
F3X89_RS17800	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_RS17810	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3X89_RS17820	COG2199	diguanylate cyclase activity
F3X89_RS17820	COG2200	EAL domain
F3X89_RS17830	COG4957	zinc ion binding
F3X89_RS17835	COG0306	phosphate transporter
F3X89_RS17870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F3X89_RS17875	COG1845	cytochrome c oxidase, subunit III
F3X89_RS17880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3X89_RS17885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3X89_RS17890	COG0477	Major facilitator Superfamily
F3X89_RS17905	COG3842	ATPase activity
F3X89_RS17910	COG1473	amidohydrolase
F3X89_RS17915	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3X89_RS17925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_RS17930	COG3300	MHYT domain
F3X89_RS17930	COG5001	Diguanylate cyclase
F3X89_RS17940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3X89_RS17940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3X89_RS17945	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3X89_RS17950	COG3454	Phosphonate metabolism
F3X89_RS17955	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3X89_RS17960	COG3639	organic phosphonate transmembrane transporter activity
F3X89_RS17975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F3X89_RS17990	COG4778	phosphonate C-P lyase system protein PhnL
F3X89_RS17995	COG4107	phosphonate C-P lyase system protein PhnK
F3X89_RS18000	COG3627	carbon phosphorus lyase activity
F3X89_RS18005	COG3626	phosphonate metabolism
F3X89_RS18010	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F3X89_RS18015	COG3624	Phosphonate C-P lyase system protein PhnG
F3X89_RS18020	COG2188	Transcriptional regulator
F3X89_RS18030	COG0588	phosphoglycerate mutase activity
F3X89_RS18035	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F3X89_RS18040	COG1132	(ABC) transporter
F3X89_RS18045	COG0837	glucose binding
F3X89_RS18050	COG1803	Methylglyoxal synthase
F3X89_RS18055	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
F3X89_RS18065	COG4166	transmembrane transport
F3X89_RS18070	COG4174	ABC transporter (Permease)
F3X89_RS18075	COG4239	(ABC) transporter, permease
F3X89_RS18080	COG4172	Belongs to the ABC transporter superfamily
F3X89_RS18085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_RS18090	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F3X89_RS18110	COG0668	transmembrane transport
F3X89_RS18125	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS18130	COG1902	pentaerythritol trinitrate reductase activity
F3X89_RS18135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F3X89_RS18165	COG0583	DNA-binding transcription factor activity
F3X89_RS18175	COG2814	Major facilitator Superfamily
F3X89_RS18185	COG0667	Aldo Keto reductase
F3X89_RS18190	COG0583	DNA-binding transcription factor activity
F3X89_RS18215	COG1744	ABC transporter substrate-binding protein PnrA-like
F3X89_RS18220	COG3845	ABC transporter
F3X89_RS18225	COG4603	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS18230	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS18240	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F3X89_RS18245	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F3X89_RS18250	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
F3X89_RS18260	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F3X89_RS18265	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F3X89_RS18270	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F3X89_RS18310	COG4964	Belongs to the GSP D family
F3X89_RS18350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F3X89_RS18370	COG0154	amidase activity
F3X89_RS18375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS18385	COG0747	negative chemotaxis
F3X89_RS18405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3X89_RS18410	COG3038	cytochrome b561
F3X89_RS18425	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
F3X89_RS18450	COG0673	inositol 2-dehydrogenase activity
F3X89_RS18460	COG0395	ABC-type sugar transport system, permease component
F3X89_RS18470	COG3842	ATPase activity
F3X89_RS18495	COG1737	Transcriptional regulator
F3X89_RS18525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3X89_RS18545	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F3X89_RS18555	COG0481	GTPase activity
F3X89_RS18580	COG5006	permease, DMT superfamily
F3X89_RS18605	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F3X89_RS18610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F3X89_RS18615	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F3X89_RS18620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F3X89_RS18625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3X89_RS18625	COG0072	phenylalanine-tRNA ligase activity
F3X89_RS18635	COG4953	penicillin-binding protein 1C
F3X89_RS18645	COG0667	Aldo Keto reductase
F3X89_RS18650	COG0583	DNA-binding transcription factor activity
F3X89_RS18665	COG0667	Aldo Keto reductase
F3X89_RS18670	COG4977	sequence-specific DNA binding
F3X89_RS18705	COG1570	exodeoxyribonuclease VII activity
F3X89_RS18710	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3X89_RS18715	COG2309	aminopeptidase activity
F3X89_RS18735	COG1393	Belongs to the ArsC family
F3X89_RS18780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3X89_RS18790	COG0583	DNA-binding transcription factor activity
F3X89_RS18795	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3X89_RS18805	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS18815	COG3663	DNA glycosylase
F3X89_RS18840	COG0583	DNA-binding transcription factor activity
F3X89_RS18845	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS18855	COG2020	methyltransferase activity
F3X89_RS18870	COG1309	transcriptional regulator
F3X89_RS18875	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F3X89_RS18875	COG0519	Catalyzes the synthesis of GMP from XMP
F3X89_RS18925	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F3X89_RS18935	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F3X89_RS18945	COG1968	undecaprenyl-diphosphatase activity
F3X89_RS18965	COG0284	orotidine-5'-phosphate decarboxylase activity
F3X89_RS18975	COG3963	phosphatidate phosphatase activity
F3X89_RS18985	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F3X89_RS18990	COG0792	nuclease activity
F3X89_RS19005	COG0189	ligase activity
F3X89_RS19020	COG1280	lysine exporter protein (LysE YggA)
F3X89_RS19025	COG1335	isochorismatase
F3X89_RS19030	COG1280	lysine exporter protein (LysE YggA)
F3X89_RS19050	COG1522	sequence-specific DNA binding
F3X89_RS19060	COG0756	dUTP diphosphatase activity
F3X89_RS19065	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F3X89_RS19090	COG0667	Aldo Keto reductase
F3X89_RS19095	COG0583	DNA-binding transcription factor activity
F3X89_RS19100	COG1720	tRNA m6t6A37 methyltransferase activity
F3X89_RS19105	COG3585	molybdate ion transport
F3X89_RS19110	COG3119	arylsulfatase activity
F3X89_RS19115	COG0583	DNA-binding transcription factor activity
F3X89_RS19120	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
F3X89_RS19125	COG1877	trehalose-phosphatase activity
F3X89_RS19135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F3X89_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS19150	COG0583	DNA-binding transcription factor activity
F3X89_RS19155	COG0583	DNA-binding transcription factor activity
F3X89_RS19160	COG2814	Major facilitator Superfamily
F3X89_RS19185	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F3X89_RS19205	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F3X89_RS19210	COG2986	histidine ammonia-lyase
F3X89_RS19220	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F3X89_RS19225	COG2226	methyltransferase
F3X89_RS19230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F3X89_RS19235	COG1024	Enoyl-CoA hydratase
F3X89_RS19240	COG0268	Binds directly to 16S ribosomal RNA
F3X89_RS19245	COG1192	Involved in chromosome partitioning
F3X89_RS19250	COG1475	DNA binding
F3X89_RS19255	COG0640	Transcriptional regulator
F3X89_RS19270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS19280	COG0583	DNA-binding transcription factor activity
F3X89_RS19330	COG0745	RESPONSE REGULATOR receiver
F3X89_RS19340	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS19345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS19360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS19410	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS19420	COG0840	transmembrane signaling receptor activity
F3X89_RS19435	COG1902	pentaerythritol trinitrate reductase activity
F3X89_RS19440	COG0427	acetyl-CoA hydrolase
F3X89_RS19445	COG3547	Transposase (IS116 IS110 IS902 family)
F3X89_RS19455	COG4208	sulfate ABC transporter
F3X89_RS19460	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_RS19470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS19480	COG3842	ATPase activity
F3X89_RS19485	COG0583	DNA-binding transcription factor activity
F3X89_RS19490	COG1126	abc transporter atp-binding protein
F3X89_RS19495	COG0765	amino acid transport
F3X89_RS19500	COG0765	amino acid transport
F3X89_RS19515	COG0667	Aldo Keto reductase
F3X89_RS19520	COG0583	DNA-binding transcription factor activity
F3X89_RS19530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3X89_RS19535	COG2267	carboxylic ester hydrolase activity
F3X89_RS19540	COG0251	oxidation-reduction process
F3X89_RS19545	COG1335	isochorismatase
F3X89_RS19550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS19555	COG5265	(ABC) transporter
F3X89_RS19570	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS19575	COG1846	Transcriptional regulator
F3X89_RS19575	COG1940	carbohydrate kinase activity
F3X89_RS19580	COG1082	Xylose isomerase domain protein TIM barrel
F3X89_RS19585	COG1917	Cupin 2, conserved barrel domain protein
F3X89_RS19585	COG2207	Transcriptional regulator
F3X89_RS19595	COG1175	transmembrane transport
F3X89_RS19610	COG1063	alcohol dehydrogenase
F3X89_RS19615	COG3842	ATPase activity
F3X89_RS19620	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS19640	COG0504	CTP synthase activity
F3X89_RS19645	COG0006	proline dipeptidase activity
F3X89_RS19650	COG4948	Mandelate Racemase Muconate Lactonizing
F3X89_RS19655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_RS19660	COG1126	abc transporter atp-binding protein
F3X89_RS19665	COG0765	amino acid transport
F3X89_RS19670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_RS19675	COG2186	Transcriptional regulator
F3X89_RS19680	COG1177	transmembrane transport
F3X89_RS19690	COG3842	ATPase activity
F3X89_RS19705	COG1024	Enoyl-CoA hydratase
F3X89_RS19715	COG0277	FAD linked oxidase domain protein
F3X89_RS19725	COG0604	alcohol dehydrogenase
F3X89_RS19730	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
F3X89_RS19735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS19760	COG1802	Transcriptional regulator
F3X89_RS19765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_RS19770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS19790	COG0765	amino acid transport
F3X89_RS19795	COG0765	amino acid transport
F3X89_RS19800	COG1126	abc transporter atp-binding protein
F3X89_RS19815	COG0444	Belongs to the ABC transporter superfamily
F3X89_RS19820	COG4608	Belongs to the ABC transporter superfamily
F3X89_RS19825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS19835	COG0747	negative chemotaxis
F3X89_RS19840	COG3257	ureidoglycine aminohydrolase activity
F3X89_RS19845	COG0583	DNA-binding transcription factor activity
F3X89_RS19850	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS19860	COG1335	isochorismatase
F3X89_RS19865	COG0583	DNA-binding transcription factor activity
F3X89_RS19870	COG0583	DNA-binding transcription factor activity
F3X89_RS19890	COG0697	spore germination
F3X89_RS19905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS19910	COG0683	leucine binding
F3X89_RS19925	COG0411	ABC transporter
F3X89_RS19940	COG1802	Transcriptional regulator
F3X89_RS19955	COG1126	abc transporter atp-binding protein
F3X89_RS19960	COG0765	amino acid transport
F3X89_RS19965	COG0765	amino acid transport
F3X89_RS19975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS19985	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS19990	COG2197	response regulator
F3X89_RS19995	COG0601	transmembrane transport
F3X89_RS20000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS20020	COG0747	negative chemotaxis
F3X89_RS20045	COG4191	Histidine kinase
F3X89_RS20045	COG0784	Response regulator, receiver
F3X89_RS20050	COG2197	response regulator
F3X89_RS20055	COG3237	CsbD-like
F3X89_RS20065	COG3920	Histidine kinase
F3X89_RS20090	COG0765	amino acid transport
F3X89_RS20095	COG4597	amino acid ABC transporter
F3X89_RS20100	COG4598	ABC transporter
F3X89_RS20115	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS20120	COG4603	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS20125	COG3845	ABC transporter
F3X89_RS20140	COG0793	Belongs to the peptidase S41A family
F3X89_RS20145	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS20155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3X89_RS20165	COG1177	transmembrane transport
F3X89_RS20170	COG3842	ATPase activity
F3X89_RS20180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_RS20185	COG0583	DNA-binding transcription factor activity
F3X89_RS20235	COG0583	DNA-binding transcription factor activity
F3X89_RS20245	COG0583	DNA-binding transcription factor activity
F3X89_RS20250	COG3384	dioxygenase
F3X89_RS20270	COG0025	NhaP-type Na H and K H
F3X89_RS20285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS20290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3X89_RS20310	COG2022	thiamine diphosphate biosynthetic process
F3X89_RS20325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
F3X89_RS20330	COG1609	Transcriptional regulator
F3X89_RS20340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_RS20345	COG0765	amino acid transport
F3X89_RS20350	COG0765	amino acid transport
F3X89_RS20360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3X89_RS20370	COG0583	DNA-binding transcription factor activity
F3X89_RS20385	COG0765	amino acid transport
F3X89_RS20390	COG1126	abc transporter atp-binding protein
F3X89_RS20395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS20400	COG1522	sequence-specific DNA binding
F3X89_RS20415	COG0667	Aldo Keto reductase
F3X89_RS20420	COG2814	Major facilitator Superfamily
F3X89_RS20430	COG0583	DNA-binding transcription factor activity
F3X89_RS20440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3X89_RS20445	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
F3X89_RS20450	COG2080	2 iron, 2 sulfur cluster binding
F3X89_RS20485	COG3153	acetyltransferase
F3X89_RS20510	COG0698	ribose 5-phosphate isomerase
F3X89_RS20515	COG0149	triose-phosphate isomerase activity
F3X89_RS20550	COG1129	ABC transporter
F3X89_RS20555	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS20560	COG1879	ABC-type sugar transport system periplasmic component
F3X89_RS20565	COG1349	DNA-binding transcription factor activity
F3X89_RS20575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F3X89_RS20585	COG0511	ligase activity, forming carbon-carbon bonds
F3X89_RS20590	COG0439	Biotin carboxylase
F3X89_RS20600	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F3X89_RS20605	COG1984	allophanate hydrolase subunit 2
F3X89_RS20610	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F3X89_RS20615	COG0436	Aminotransferase
F3X89_RS20625	COG4221	oxidoreductase activity
F3X89_RS20630	COG0765	amino acid transport
F3X89_RS20635	COG0765	amino acid transport
F3X89_RS20650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3X89_RS20660	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F3X89_RS20690	COG3842	ATPase activity
F3X89_RS20695	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_RS20710	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS20720	COG3842	ATPase activity
F3X89_RS20725	COG0726	polysaccharide deacetylase
F3X89_RS20735	COG0523	cobalamin synthesis protein
F3X89_RS20745	COG0154	amidase activity
F3X89_RS20750	COG2909	trisaccharide binding
F3X89_RS20765	COG3842	ATPase activity
F3X89_RS20775	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_RS20780	COG1177	transmembrane transport
F3X89_RS20785	COG1129	ABC transporter
F3X89_RS20790	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS20795	COG1879	ABC-type sugar transport system periplasmic component
F3X89_RS20800	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS20805	COG2376	Dihydroxyacetone kinase
F3X89_RS20815	COG2376	Dihydroxyacetone kinase
F3X89_RS20840	COG2207	Transcriptional regulator
F3X89_RS20845	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS20855	COG1335	isochorismatase
F3X89_RS20865	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS20940	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS20945	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
F3X89_RS20950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F3X89_RS20970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3X89_RS20975	COG0784	Response regulator, receiver
F3X89_RS20975	COG4191	Histidine kinase
F3X89_RS20985	COG1294	oxidase, subunit
F3X89_RS20990	COG1271	oxidase subunit
F3X89_RS20995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F3X89_RS21000	COG4988	ABC transporter
F3X89_RS21010	COG0517	IMP dehydrogenase activity
F3X89_RS21010	COG0516	GMP reductase activity
F3X89_RS21045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3X89_RS21050	COG3609	addiction module antidote protein, CC2985 family
F3X89_RS21055	COG3668	Plasmid stabilization system
F3X89_RS21095	COG2208	phosphoserine phosphatase activity
F3X89_RS21100	COG2226	methyltransferase
F3X89_RS21110	COG5001	Diguanylate cyclase
F3X89_RS21110	COG3300	MHYT domain
F3X89_RS21115	COG0745	RESPONSE REGULATOR receiver
F3X89_RS21115	COG3292	Two component regulator propeller
F3X89_RS21115	COG2205	protein histidine kinase activity
F3X89_RS21125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3X89_RS21135	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F3X89_RS21175	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
F3X89_RS21175	COG2273	Hydrolase Family 16
F3X89_RS21200	COG2197	response regulator
F3X89_RS21205	COG2890	protein-(glutamine-N5) methyltransferase activity
F3X89_RS21210	COG0367	asparagine synthase
F3X89_RS21220	COG0318	PFAM AMP-dependent synthetase and ligase
F3X89_RS21225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F3X89_RS21230	COG3321	synthase
F3X89_RS21230	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F3X89_RS21230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3X89_RS21230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3X89_RS21240	COG5001	Diguanylate cyclase
F3X89_RS21240	COG3300	MHYT domain
F3X89_RS21250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F3X89_RS21280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS21285	COG1116	anion transmembrane transporter activity
F3X89_RS21290	COG4191	Histidine kinase
F3X89_RS21300	COG1609	Transcriptional regulator
F3X89_RS21305	COG2271	Major facilitator Superfamily
F3X89_RS21310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_RS21315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_RS21365	COG4774	siderophore transport
F3X89_RS21370	COG2814	Major facilitator Superfamily
F3X89_RS21385	COG1473	amidohydrolase
F3X89_RS21400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS21410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS21455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS21470	COG0667	Aldo Keto reductase
F3X89_RS21485	COG0747	negative chemotaxis
F3X89_RS21490	COG0583	DNA-binding transcription factor activity
F3X89_RS21495	COG0778	Nitroreductase
F3X89_RS21515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS21530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_RS21535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS21540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS21545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS21550	COG0454	-acetyltransferase
F3X89_RS21555	COG0747	negative chemotaxis
F3X89_RS21560	COG0747	negative chemotaxis
F3X89_RS21580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS21635	COG1653	transport
F3X89_RS21640	COG2188	Transcriptional regulator
F3X89_RS21660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS21665	COG0601	transmembrane transport
F3X89_RS21670	COG0747	negative chemotaxis
F3X89_RS21675	COG2186	Transcriptional regulator
F3X89_RS21680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_RS21685	COG0747	negative chemotaxis
F3X89_RS21690	COG0601	transmembrane transport
F3X89_RS21695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS21700	COG0444	Belongs to the ABC transporter superfamily
F3X89_RS21705	COG4608	Belongs to the ABC transporter superfamily
F3X89_RS21710	COG0483	inositol monophosphate 1-phosphatase activity
F3X89_RS21715	COG0584	glycerophosphoryl diester phosphodiesterase
F3X89_RS21720	COG1940	carbohydrate kinase activity
F3X89_RS21725	COG3300	MHYT domain
F3X89_RS21725	COG5001	Diguanylate cyclase
F3X89_RS21745	COG3755	Protein conserved in bacteria
F3X89_RS21765	COG0840	transmembrane signaling receptor activity
F3X89_RS21770	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS21775	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS21780	COG1129	ABC transporter
F3X89_RS21795	COG0477	Major facilitator Superfamily
F3X89_RS21800	COG1309	transcriptional regulator
F3X89_RS21805	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3X89_RS21815	COG3344	reverse transcriptase
F3X89_RS21835	COG1396	sequence-specific DNA binding
F3X89_RS21845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3X89_RS21870	COG3177	Filamentation induced by cAMP protein fic
F3X89_RS21900	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
F3X89_RS22005	COG4467	Involved in initiation control of chromosome replication
F3X89_RS22040	COG1802	Transcriptional regulator
F3X89_RS22045	COG3938	Belongs to the proline racemase family
F3X89_RS22065	COG1126	abc transporter atp-binding protein
F3X89_RS22070	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS22080	COG0673	inositol 2-dehydrogenase activity
F3X89_RS22085	COG0395	ABC-type sugar transport system, permease component
F3X89_RS22090	COG1175	transmembrane transport
F3X89_RS22100	COG1653	transport
F3X89_RS22105	COG1335	isochorismatase
F3X89_RS22130	COG1744	ABC transporter substrate-binding protein PnrA-like
F3X89_RS22135	COG3845	ABC transporter
F3X89_RS22145	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS22165	COG0583	DNA-binding transcription factor activity
F3X89_RS22175	COG2963	transposase activity
F3X89_RS22180	COG3436	PFAM IS66 Orf2 family protein
F3X89_RS22190	COG4974	Belongs to the 'phage' integrase family
F3X89_RS22195	COG0582	viral genome integration into host DNA
F3X89_RS22200	COG4974	Belongs to the 'phage' integrase family
F3X89_RS22215	COG1454	alcohol dehydrogenase
F3X89_RS22235	COG0583	DNA-binding transcription factor activity
F3X89_RS22250	COG2226	methyltransferase
F3X89_RS22285	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F3X89_RS22320	COG2375	cellular response to nickel ion
F3X89_RS22320	COG1132	(ABC) transporter
F3X89_RS22330	COG4774	siderophore transport
F3X89_RS22335	COG1309	transcriptional regulator
F3X89_RS22345	COG1982	Orn Lys Arg decarboxylase major
F3X89_RS22360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3X89_RS22360	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
F3X89_RS22365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3X89_RS22370	COG1169	isochorismate synthase
F3X89_RS22375	COG1021	2,3-dihydroxybenzoate-AMP ligase
F3X89_RS22385	COG1169	isochorismate synthase
F3X89_RS22435	COG1335	isochorismatase
F3X89_RS22440	COG3845	ABC transporter
F3X89_RS22455	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS22490	COG2814	Major facilitator Superfamily
F3X89_RS22495	COG0656	L-ascorbic acid biosynthetic process
F3X89_RS22500	COG0667	Aldo Keto reductase
F3X89_RS22525	COG1073	alpha beta
F3X89_RS22575	COG0339	signal peptide processing
F3X89_RS22620	COG1396	sequence-specific DNA binding
F3X89_RS22710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS22720	COG0747	negative chemotaxis
F3X89_RS22725	COG1737	Transcriptional regulator
F3X89_RS22735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS22745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_RS22750	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F3X89_RS22755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS22770	COG1024	Enoyl-CoA hydratase
F3X89_RS22775	COG0583	DNA-binding transcription factor activity
F3X89_RS22780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F3X89_RS22790	COG0583	DNA-binding transcription factor activity
F3X89_RS22795	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3X89_RS22800	COG3842	ATPase activity
F3X89_RS22805	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_RS22810	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F3X89_RS22815	COG2072	flavoprotein involved in K transport
F3X89_RS22835	COG0402	S-adenosylhomocysteine deaminase activity
F3X89_RS22850	COG0583	DNA-binding transcription factor activity
F3X89_RS22855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS22870	COG3547	Transposase (IS116 IS110 IS902 family)
F3X89_RS22890	COG1846	Transcriptional regulator
F3X89_RS22910	COG5001	Diguanylate cyclase
F3X89_RS22910	COG3300	MHYT domain
F3X89_RS22930	COG0583	DNA-binding transcription factor activity
F3X89_RS22935	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS22940	COG3959	Transketolase, thiamine diphosphate binding domain
F3X89_RS22945	COG3958	Transketolase
F3X89_RS22950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3X89_RS22955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3X89_RS22960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3X89_RS22965	COG1129	ABC transporter
F3X89_RS22970	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS22975	COG1879	ABC-type sugar transport system periplasmic component
F3X89_RS22980	COG3618	amidohydrolase
F3X89_RS22985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3X89_RS22990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F3X89_RS22995	COG0583	DNA-binding transcription factor activity
F3X89_RS23025	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS23030	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS23035	COG4177	L-phenylalanine transmembrane transporter activity
F3X89_RS23040	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS23050	COG1137	ATPase activity
F3X89_RS23075	COG1024	Enoyl-CoA hydratase
F3X89_RS23155	COG2072	flavoprotein involved in K transport
F3X89_RS23165	COG1845	cytochrome c oxidase, subunit III
F3X89_RS23170	COG1845	cytochrome c oxidase, subunit III
F3X89_RS23175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3X89_RS23180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3X89_RS23215	COG4221	oxidoreductase activity
F3X89_RS23220	COG1309	transcriptional regulator
F3X89_RS23230	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F3X89_RS23240	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F3X89_RS23260	COG1349	DNA-binding transcription factor activity
F3X89_RS23275	COG2072	flavoprotein involved in K transport
F3X89_RS23300	COG1335	isochorismatase
F3X89_RS23315	COG0434	BtpA family
F3X89_RS23320	COG1070	Carbohydrate kinase
F3X89_RS23350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_RS23355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS23370	COG1733	regulation of RNA biosynthetic process
F3X89_RS23400	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS23405	COG3321	synthase
F3X89_RS23405	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS23405	COG0604	alcohol dehydrogenase
F3X89_RS23410	COG1073	alpha beta
F3X89_RS23420	COG1335	isochorismatase
F3X89_RS23430	COG0583	DNA-binding transcription factor activity
F3X89_RS23435	COG1741	Belongs to the pirin family
F3X89_RS23455	COG1228	amidohydrolase
F3X89_RS23470	COG2207	Transcriptional regulator
F3X89_RS23490	COG2814	Major facilitator Superfamily
F3X89_RS23500	COG3547	Transposase (IS116 IS110 IS902 family)
F3X89_RS23505	COG2072	flavoprotein involved in K transport
F3X89_RS23525	COG1472	Belongs to the glycosyl hydrolase 3 family
F3X89_RS23540	COG0395	ABC-type sugar transport system, permease component
F3X89_RS23545	COG1175	transmembrane transport
F3X89_RS23550	COG1653	transport
F3X89_RS23570	COG0601	transmembrane transport
F3X89_RS23580	COG4608	Belongs to the ABC transporter superfamily
F3X89_RS23590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_RS23655	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS23670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_RS23675	COG0159	tryptophan synthase activity
F3X89_RS23685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_RS23690	COG3842	ATPase activity
F3X89_RS23695	COG3833	ABC-type maltose transport systems, permease component
F3X89_RS23700	COG1175	transmembrane transport
F3X89_RS23715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_RS23725	COG1595	DNA-templated transcription, initiation
F3X89_RS23760	COG0444	Belongs to the ABC transporter superfamily
F3X89_RS23765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_RS23780	COG0747	negative chemotaxis
F3X89_RS23785	COG2186	Transcriptional regulator
F3X89_RS23810	COG3842	ATPase activity
F3X89_RS23845	COG2272	Belongs to the type-B carboxylesterase lipase family
F3X89_RS23860	COG2211	Major facilitator Superfamily
F3X89_RS23880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3X89_RS23890	COG1280	lysine exporter protein (LysE YggA)
F3X89_RS23895	COG2197	response regulator
F3X89_RS23905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F3X89_RS23910	COG0720	synthase
F3X89_RS23915	COG0602	queuosine metabolic process
F3X89_RS23930	COG2267	carboxylic ester hydrolase activity
F3X89_RS23940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS23945	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS23965	COG1177	transmembrane transport
F3X89_RS23970	COG3842	ATPase activity
F3X89_RS23980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS23995	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS24005	COG0410	ABC transporter
F3X89_RS24015	COG2706	6-phosphogluconolactonase activity
F3X89_RS24020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_RS24025	COG1312	Catalyzes the dehydration of D-mannonate
F3X89_RS24030	COG2186	Transcriptional regulator
F3X89_RS24040	COG0601	transmembrane transport
F3X89_RS24045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS24100	COG4774	siderophore transport
F3X89_RS24115	COG1473	amidohydrolase
F3X89_RS24120	COG0747	negative chemotaxis
F3X89_RS24125	COG0601	transmembrane transport
F3X89_RS24130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS24135	COG4172	Belongs to the ABC transporter superfamily
F3X89_RS24145	COG3386	PFAM SMP-30 Gluconolaconase
F3X89_RS24155	COG1063	alcohol dehydrogenase
F3X89_RS24160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3X89_RS24165	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS24170	COG2084	Dehydrogenase
F3X89_RS24180	COG1609	Transcriptional regulator
F3X89_RS24190	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS24195	COG1129	ABC transporter
F3X89_RS24205	COG0840	transmembrane signaling receptor activity
F3X89_RS24225	COG4214	carbohydrate transport
F3X89_RS24235	COG1070	Carbohydrate kinase
F3X89_RS24240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS24245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS24250	COG0601	transmembrane transport
F3X89_RS24275	COG4172	Belongs to the ABC transporter superfamily
F3X89_RS24280	COG3842	ATPase activity
F3X89_RS24290	COG0516	GMP reductase activity
F3X89_RS24305	COG0673	inositol 2-dehydrogenase activity
F3X89_RS24315	COG0395	ABC-type sugar transport system, permease component
F3X89_RS24330	COG0673	inositol 2-dehydrogenase activity
F3X89_RS24345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_RS24350	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
F3X89_RS24355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3X89_RS24360	COG2390	Transcriptional regulator
F3X89_RS24370	COG1940	carbohydrate kinase activity
F3X89_RS24375	COG1879	ABC-type sugar transport system periplasmic component
F3X89_RS24405	COG0765	amino acid transport
F3X89_RS24410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_RS24420	COG1126	abc transporter atp-binding protein
F3X89_RS24440	COG1522	sequence-specific DNA binding
F3X89_RS24495	COG0864	Transcriptional regulator
F3X89_RS24505	COG1609	Transcriptional regulator
F3X89_RS24530	COG0697	spore germination
F3X89_RS24535	COG3206	protein involved in exopolysaccharide biosynthesis
F3X89_RS24535	COG0489	protein tyrosine kinase activity
F3X89_RS24540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3X89_RS24545	COG1215	transferase activity, transferring glycosyl groups
F3X89_RS24550	COG1215	transferase activity, transferring glycosyl groups
F3X89_RS24555	COG1215	transferase activity, transferring glycosyl groups
F3X89_RS24560	COG0438	transferase activity, transferring glycosyl groups
F3X89_RS24565	COG2273	Hydrolase Family 16
F3X89_RS24570	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3X89_RS24580	COG2244	polysaccharide biosynthetic process
F3X89_RS24585	COG0463	Glycosyl transferase, family 2
F3X89_RS24590	COG2327	Polysaccharide pyruvyl transferase
F3X89_RS24595	COG1215	transferase activity, transferring glycosyl groups
F3X89_RS24610	COG1596	polysaccharide export
F3X89_RS24615	COG3307	-O-antigen
F3X89_RS24620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3X89_RS24630	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS24650	COG2721	sulfolactate sulfo-lyase activity
F3X89_RS24665	COG2207	Transcriptional regulator
F3X89_RS24670	COG1486	melibiose metabolic process
F3X89_RS24675	COG0747	negative chemotaxis
F3X89_RS24680	COG0601	transmembrane transport
F3X89_RS24685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS24690	COG4172	Belongs to the ABC transporter superfamily
F3X89_RS24695	COG1486	melibiose metabolic process
F3X89_RS24715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3X89_RS24715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3X89_RS24720	COG1132	(ABC) transporter
F3X89_RS24740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS24750	COG0747	negative chemotaxis
F3X89_RS24780	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3X89_RS24795	COG1234	tRNA 3'-trailer cleavage
F3X89_RS24820	COG0559	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS24830	COG0683	leucine binding
F3X89_RS24840	COG3485	protocatechuate 3,4-dioxygenase
F3X89_RS24845	COG3485	protocatechuate 3,4-dioxygenase
F3X89_RS24850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3X89_RS24855	COG2267	carboxylic ester hydrolase activity
F3X89_RS24860	COG0583	DNA-binding transcription factor activity
F3X89_RS24875	COG1414	Transcriptional regulator
F3X89_RS24885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3X89_RS24895	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS24930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3X89_RS24945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3X89_RS24950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F3X89_RS24955	COG4208	sulfate ABC transporter
F3X89_RS24965	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F3X89_RS24970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3X89_RS24980	COG2205	protein histidine kinase activity
F3X89_RS24985	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F3X89_RS24990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F3X89_RS24995	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F3X89_RS25030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS25035	COG0444	Belongs to the ABC transporter superfamily
F3X89_RS25040	COG4608	Belongs to the ABC transporter superfamily
F3X89_RS25055	COG2197	response regulator
F3X89_RS25060	COG2205	protein histidine kinase activity
F3X89_RS25060	COG0784	Response regulator, receiver
F3X89_RS25075	COG0235	Class ii aldolase
F3X89_RS25080	COG3395	kinase activity
F3X89_RS25085	COG3622	Belongs to the hyi family
F3X89_RS25090	COG2084	Dehydrogenase
F3X89_RS25100	COG1609	Transcriptional regulator
F3X89_RS25110	COG0765	amino acid transport
F3X89_RS25115	COG0765	amino acid transport
F3X89_RS25125	COG0251	oxidation-reduction process
F3X89_RS25140	COG0235	Class ii aldolase
F3X89_RS25150	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS25155	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS25160	COG1129	ABC transporter
F3X89_RS25170	COG1609	Transcriptional regulator
F3X89_RS25190	COG1215	transferase activity, transferring glycosyl groups
F3X89_RS25230	COG1278	Cold shock
F3X89_RS25245	COG0659	secondary active sulfate transmembrane transporter activity
F3X89_RS25275	COG2205	protein histidine kinase activity
F3X89_RS25280	COG1396	sequence-specific DNA binding
F3X89_RS25315	COG1596	polysaccharide export
F3X89_RS25320	COG0438	transferase activity, transferring glycosyl groups
F3X89_RS25355	COG1215	transferase activity, transferring glycosyl groups
F3X89_RS25395	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
F3X89_RS25420	COG0583	DNA-binding transcription factor activity
F3X89_RS25425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS25430	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS25435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS25470	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS25480	COG1473	amidohydrolase
F3X89_RS25495	COG0601	transmembrane transport
F3X89_RS25510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3X89_RS25525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3X89_RS25535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS25540	COG0601	transmembrane transport
F3X89_RS25545	COG0747	negative chemotaxis
F3X89_RS25550	COG0306	phosphate transporter
F3X89_RS25555	COG1392	Phosphate transport regulator
F3X89_RS25560	COG3842	ATPase activity
F3X89_RS25565	COG0395	ABC-type sugar transport system, permease component
F3X89_RS25570	COG1175	transmembrane transport
F3X89_RS25575	COG1653	transport
F3X89_RS25580	COG0697	spore germination
F3X89_RS25605	COG0747	negative chemotaxis
F3X89_RS25615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS25625	COG1733	regulation of RNA biosynthetic process
F3X89_RS25635	COG1132	(ABC) transporter
F3X89_RS25640	COG0463	Glycosyl transferase, family 2
F3X89_RS25645	COG1216	Glycosyl transferase, family 2
F3X89_RS25650	COG2755	lipolytic protein G-D-S-L family
F3X89_RS25650	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3X89_RS25660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS25665	COG2079	MmgE PrpD family protein
F3X89_RS25670	COG1126	abc transporter atp-binding protein
F3X89_RS25675	COG0765	amino acid transport
F3X89_RS25700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3X89_RS25705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3X89_RS25710	COG1120	ATPase activity
F3X89_RS25720	COG3300	MHYT domain
F3X89_RS25720	COG5001	Diguanylate cyclase
F3X89_RS25740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS25745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3X89_RS25755	COG0583	DNA-binding transcription factor activity
F3X89_RS25770	COG0657	acetylesterase activity
F3X89_RS25780	COG4166	transmembrane transport
F3X89_RS25795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS25800	COG0601	transmembrane transport
F3X89_RS25805	COG0747	negative chemotaxis
F3X89_RS25820	COG1960	acyl-CoA dehydrogenase activity
F3X89_RS25825	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3X89_RS25825	COG0824	Thioesterase
F3X89_RS25830	COG3246	L-lysine catabolic process to acetate
F3X89_RS25840	COG0583	DNA-binding transcription factor activity
F3X89_RS25850	COG1609	Transcriptional regulator
F3X89_RS25855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_RS25860	COG1126	abc transporter atp-binding protein
F3X89_RS25865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS25885	COG3842	ATPase activity
F3X89_RS25895	COG0395	ABC-type sugar transport system, permease component
F3X89_RS25910	COG1461	Dihydroxyacetone kinase
F3X89_RS25915	COG2376	Dihydroxyacetone kinase
F3X89_RS25925	COG0673	inositol 2-dehydrogenase activity
F3X89_RS25930	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS25935	COG1129	ABC transporter
F3X89_RS25945	COG1879	ABC-type sugar transport system periplasmic component
F3X89_RS25950	COG0287	Prephenate dehydrogenase
F3X89_RS25960	COG1850	ribulose-bisphosphate carboxylase activity
F3X89_RS25965	COG2186	Transcriptional regulator
F3X89_RS25975	COG1968	undecaprenyl-diphosphatase activity
F3X89_RS25980	COG2824	Alkylphosphonate utilization operon protein PhnA
F3X89_RS25995	COG0352	thiamine-phosphate diphosphorylase activity
F3X89_RS26000	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
F3X89_RS26010	COG0625	glutathione transferase activity
F3X89_RS26025	COG2204	response regulator
F3X89_RS26030	COG4191	Histidine kinase
F3X89_RS26035	COG1301	dicarboxylic acid transport
F3X89_RS26040	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
F3X89_RS26045	COG1136	(ABC) transporter
F3X89_RS26045	COG0577	efflux transmembrane transporter activity
F3X89_RS26055	COG1136	(ABC) transporter
F3X89_RS26065	COG2169	Transcriptional regulator
F3X89_RS26070	COG1414	Transcriptional regulator
F3X89_RS26080	COG0747	negative chemotaxis
F3X89_RS26100	COG4774	siderophore transport
F3X89_RS26110	COG2819	hydrolase of the alpha beta superfamily
F3X89_RS26115	COG1120	ATPase activity
F3X89_RS26120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3X89_RS26130	COG1522	sequence-specific DNA binding
F3X89_RS26135	COG4172	Belongs to the ABC transporter superfamily
F3X89_RS26140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS26145	COG0601	transmembrane transport
F3X89_RS26175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS26180	COG0251	oxidation-reduction process
F3X89_RS26200	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS26210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_RS26215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_RS26225	COG0454	-acetyltransferase
F3X89_RS26240	COG1414	Transcriptional regulator
F3X89_RS26250	COG3547	Transposase (IS116 IS110 IS902 family)
F3X89_RS26260	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F3X89_RS26345	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F3X89_RS26370	COG1136	(ABC) transporter
F3X89_RS26370	COG0577	efflux transmembrane transporter activity
F3X89_RS26375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS26390	COG0436	Aminotransferase
F3X89_RS26400	COG0583	DNA-binding transcription factor activity
F3X89_RS26415	COG0765	amino acid transport
F3X89_RS26420	COG0765	amino acid transport
F3X89_RS26425	COG1126	abc transporter atp-binding protein
F3X89_RS26445	COG2197	response regulator
F3X89_RS26450	COG4585	Histidine kinase
F3X89_RS26460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_RS26470	COG0006	proline dipeptidase activity
F3X89_RS26475	COG3842	ATPase activity
F3X89_RS26480	COG0395	ABC-type sugar transport system, permease component
F3X89_RS26495	COG0626	cystathionine gamma-synthase activity
F3X89_RS26500	COG2186	Transcriptional regulator
F3X89_RS26505	COG0657	acetylesterase activity
F3X89_RS26505	COG2755	lipolytic protein G-D-S-L family
F3X89_RS26525	COG3842	ATPase activity
F3X89_RS26535	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_RS26540	COG0395	ABC-type sugar transport system, permease component
F3X89_RS26560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS26565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS26570	COG1473	amidohydrolase
F3X89_RS26580	COG1126	abc transporter atp-binding protein
F3X89_RS26585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_RS26595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_RS26600	COG1215	transferase activity, transferring glycosyl groups
F3X89_RS26610	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS26615	COG1129	ABC transporter
F3X89_RS26620	COG4213	ABC transporter substrate-binding protein
F3X89_RS26635	COG4993	Dehydrogenase
F3X89_RS26655	COG1846	Transcriptional regulator
F3X89_RS26655	COG1940	carbohydrate kinase activity
F3X89_RS26670	COG0395	ABC-type sugar transport system, permease component
F3X89_RS26730	COG0277	FAD linked oxidase domain protein
F3X89_RS26760	COG3344	reverse transcriptase
F3X89_RS26770	COG1902	pentaerythritol trinitrate reductase activity
F3X89_RS26775	COG4221	oxidoreductase activity
F3X89_RS26815	COG0667	Aldo Keto reductase
F3X89_RS26830	COG1902	pentaerythritol trinitrate reductase activity
F3X89_RS26830	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3X89_RS26840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3X89_RS26850	COG4176	ABC-type proline glycine betaine transport system permease component
F3X89_RS26855	COG0517	IMP dehydrogenase activity
F3X89_RS26855	COG4175	Glycine betaine
F3X89_RS26860	COG1278	Cold shock
F3X89_RS26865	COG5342	invasion associated locus B
F3X89_RS26905	COG1349	DNA-binding transcription factor activity
F3X89_RS26915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_RS26930	COG1175	transmembrane transport
F3X89_RS26935	COG0395	ABC-type sugar transport system, permease component
F3X89_RS26940	COG2204	response regulator
F3X89_RS26945	COG4191	Histidine kinase
F3X89_RS26960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3X89_RS26970	COG1609	Transcriptional regulator
F3X89_RS26980	COG1175	transmembrane transport
F3X89_RS26985	COG0395	ABC-type sugar transport system, permease component
F3X89_RS27005	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3X89_RS27010	COG0625	glutathione transferase activity
F3X89_RS27030	COG3845	ABC transporter
F3X89_RS27040	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS27055	COG0243	molybdopterin cofactor binding
F3X89_RS27065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F3X89_RS27070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3X89_RS27080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS27085	COG0601	transmembrane transport
F3X89_RS27090	COG0747	negative chemotaxis
F3X89_RS27095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F3X89_RS27100	COG2971	BadF BadG BcrA BcrD
F3X89_RS27105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F3X89_RS27110	COG1737	Transcriptional regulator
F3X89_RS27115	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS27125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F3X89_RS27130	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F3X89_RS27155	COG1116	anion transmembrane transporter activity
F3X89_RS27160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_RS27170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3X89_RS27175	COG0747	negative chemotaxis
F3X89_RS27180	COG4608	Belongs to the ABC transporter superfamily
F3X89_RS27200	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS27205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS27210	COG0601	transmembrane transport
F3X89_RS27225	COG0584	glycerophosphoryl diester phosphodiesterase
F3X89_RS27230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS27240	COG4172	Belongs to the ABC transporter superfamily
F3X89_RS27255	COG1609	Transcriptional regulator
F3X89_RS27270	COG2137	regulation of response to DNA damage stimulus
F3X89_RS27275	COG1802	Transcriptional regulator
F3X89_RS27280	COG1126	abc transporter atp-binding protein
F3X89_RS27285	COG0765	amino acid transport
F3X89_RS27290	COG0765	amino acid transport
F3X89_RS27300	COG1063	alcohol dehydrogenase
F3X89_RS27305	COG0246	Mannitol dehydrogenase
F3X89_RS27310	COG1312	Catalyzes the dehydration of D-mannonate
F3X89_RS27315	COG1802	Transcriptional regulator
F3X89_RS27320	COG0667	Aldo Keto reductase
F3X89_RS27330	COG1473	amidohydrolase
F3X89_RS27355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F3X89_RS27360	COG0667	Aldo Keto reductase
F3X89_RS27365	COG0583	DNA-binding transcription factor activity
F3X89_RS27370	COG0450	alkyl hydroperoxide reductase
F3X89_RS27390	COG2273	Hydrolase Family 16
F3X89_RS27390	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
F3X89_RS27395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_RS27400	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
F3X89_RS27405	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F3X89_RS27410	COG2894	cell division
F3X89_RS27415	COG0850	regulation of cytokinetic process
F3X89_RS27420	COG0668	transmembrane transport
F3X89_RS27430	COG0252	asparaginase activity
F3X89_RS27440	COG1027	Aspartate ammonia-lyase
F3X89_RS27445	COG2186	Transcriptional regulator
F3X89_RS27475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_RS27480	COG4172	Belongs to the ABC transporter superfamily
F3X89_RS27485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS27500	COG1802	Transcriptional regulator
F3X89_RS27505	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F3X89_RS27510	COG1522	sequence-specific DNA binding
F3X89_RS27520	COG0318	PFAM AMP-dependent synthetase and ligase
F3X89_RS27535	COG1802	Transcriptional regulator
F3X89_RS27540	COG1984	allophanate hydrolase subunit 2
F3X89_RS27545	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F3X89_RS27550	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F3X89_RS27565	COG0765	amino acid transport
F3X89_RS27570	COG0765	amino acid transport
F3X89_RS27580	COG0010	Belongs to the arginase family
F3X89_RS27600	COG2072	flavoprotein involved in K transport
F3X89_RS27605	COG1126	abc transporter atp-binding protein
F3X89_RS27610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_RS27615	COG0765	amino acid transport
F3X89_RS27620	COG0765	amino acid transport
F3X89_RS27630	COG1921	L-seryl-tRNASec selenium transferase activity
F3X89_RS27645	COG3964	amidohydrolase
F3X89_RS27655	COG0601	transmembrane transport
F3X89_RS27660	COG0747	negative chemotaxis
F3X89_RS27685	COG0028	Belongs to the TPP enzyme family
F3X89_RS27690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3X89_RS27705	COG2837	iron assimilation
F3X89_RS27720	COG0542	response to heat
F3X89_RS27725	COG4191	Histidine kinase
F3X89_RS27740	COG0484	heat shock protein binding
F3X89_RS27750	COG0303	'Molybdopterin
F3X89_RS27755	COG0668	transmembrane transport
F3X89_RS27760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F3X89_RS27780	COG1294	oxidase, subunit
F3X89_RS27785	COG1271	oxidase subunit
F3X89_RS27790	COG0243	molybdopterin cofactor binding
F3X89_RS27795	COG3781	membrane
F3X89_RS27830	COG0300	oxidoreductase activity
F3X89_RS27855	COG0667	Aldo Keto reductase
F3X89_RS27865	COG1902	pentaerythritol trinitrate reductase activity
F3X89_RS27880	COG1840	ABC-type Fe3 transport system, periplasmic component
F3X89_RS27890	COG3842	ATPase activity
F3X89_RS27920	COG1215	transferase activity, transferring glycosyl groups
F3X89_RS27930	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F3X89_RS27940	COG4251	negative regulation of phosphorylation
F3X89_RS27940	COG3706	GGDEF domain
F3X89_RS27940	COG2203	Gaf domain
F3X89_RS27940	COG5001	Diguanylate cyclase
F3X89_RS27945	COG1609	Transcriptional regulator
F3X89_RS27955	COG1129	ABC transporter
F3X89_RS27960	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS28015	COG1459	type II secretion system
F3X89_RS28020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F3X89_RS28045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_RS28075	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_RS28090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_RS28095	COG1473	amidohydrolase
F3X89_RS28120	COG0436	Aminotransferase
F3X89_RS28130	COG4302	ethanolamine ammonia-lyase activity
F3X89_RS28135	COG4303	Ethanolamine ammonia lyase large subunit
F3X89_RS28155	COG0235	Class ii aldolase
F3X89_RS28165	COG3239	Fatty acid desaturase
F3X89_RS28180	COG1116	anion transmembrane transporter activity
F3X89_RS28190	COG3665	Urea carboxylase-associated protein
F3X89_RS28195	COG4770	biotin carboxylase activity
F3X89_RS28205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3X89_RS28235	COG0596	Alpha beta hydrolase
F3X89_RS28345	COG0583	DNA-binding transcription factor activity
F3X89_RS28350	COG5383	Protein conserved in bacteria
F3X89_RS28355	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_RS28360	COG0436	Aminotransferase
F3X89_RS28365	COG0277	FAD linked oxidase domain protein
F3X89_RS28365	COG0247	lactate metabolic process
F3X89_RS28375	COG1522	sequence-specific DNA binding
F3X89_RS28380	COG0154	amidase activity
F3X89_RS28385	COG1231	oxidoreductase activity
F3X89_RS28395	COG2222	sugar isomerase
F3X89_RS28400	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_RS28405	COG0006	proline dipeptidase activity
F3X89_RS28415	COG0667	Aldo Keto reductase
F3X89_RS28425	COG0300	oxidoreductase activity
F3X89_RS28445	COG0006	proline dipeptidase activity
F3X89_RS28450	COG3842	ATPase activity
F3X89_RS28470	COG0840	transmembrane signaling receptor activity
F3X89_RS28470	COG2972	Histidine kinase
F3X89_RS28490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3X89_RS28495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
F3X89_RS28500	COG2080	2 iron, 2 sulfur cluster binding
F3X89_RS28505	COG2814	Major facilitator Superfamily
F3X89_RS28545	COG1064	alcohol dehydrogenase
F3X89_RS28555	COG0655	NAD(P)H dehydrogenase (quinone) activity
F3X89_RS28560	COG0583	DNA-binding transcription factor activity
F3X89_RS28565	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
F3X89_RS28600	COG4302	ethanolamine ammonia-lyase activity
F3X89_RS28605	COG4303	Ethanolamine ammonia lyase large subunit
F3X89_RS28615	COG0154	amidase activity
F3X89_RS28630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS28635	COG4172	Belongs to the ABC transporter superfamily
F3X89_RS28640	COG1349	DNA-binding transcription factor activity
F3X89_RS28645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_RS28665	COG1940	carbohydrate kinase activity
F3X89_RS28675	COG1879	ABC-type sugar transport system periplasmic component
F3X89_RS28685	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_RS28700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F3X89_RS28710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3X89_RS28715	COG0563	adenylate kinase activity
F3X89_RS28720	COG2972	Histidine kinase
F3X89_RS28720	COG0840	transmembrane signaling receptor activity
F3X89_RS28730	COG0191	fructose-bisphosphate aldolase activity
F3X89_RS28735	COG0149	triose-phosphate isomerase activity
F3X89_RS28780	COG1475	DNA binding
F3X89_RS28820	COG4227	nucleotidyltransferase activity
F3X89_RS28830	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F3X89_RS28835	COG5489	Protein of unknown function (DUF736)
F3X89_RS28840	COG2161	toxin-antitoxin pair type II binding
F3X89_RS28855	COG5489	Protein of unknown function (DUF736)
F3X89_RS28865	COG3831	ATPase activity
F3X89_RS28875	COG1879	ABC-type sugar transport system periplasmic component
F3X89_RS28880	COG0840	transmembrane signaling receptor activity
F3X89_RS28890	COG3505	Type IV secretory pathway VirD4
F3X89_RS28905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3X89_RS28910	COG4959	Type IV secretory pathway protease TraF
F3X89_RS28915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3X89_RS28935	COG1476	TRANSCRIPTIONal
F3X89_RS28945	COG2771	luxR family
F3X89_RS28950	COG2948	multi-organism process
F3X89_RS28960	COG3504	Conjugal transfer protein
F3X89_RS28965	COG3701	Conjugal transfer protein
F3X89_RS28970	COG3846	protein secretion by the type IV secretion system
F3X89_RS28980	COG5314	conjugation
F3X89_RS28990	COG5268	conjugation
F3X89_RS28995	COG3838	Conjugal transfer protein Trbc
F3X89_RS29000	COG4962	Type ii secretion system protein e
F3X89_RS29005	COG3916	Acyl-homoserine-lactone synthase
F3X89_RS29010	COG1192	Involved in chromosome partitioning
F3X89_RS29015	COG1475	DNA binding
F3X89_RS29020	COG0640	Transcriptional regulator
F3X89_RS29025	COG2963	transposase activity
F3X89_RS29060	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F3X89_RS29170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F3X89_RS29180	COG3436	PFAM IS66 Orf2 family protein
F3X89_RS29185	COG2963	transposase activity
F3X89_RS29190	COG3161	chorismate lyase activity
F3X89_RS29195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F3X89_RS29265	COG0745	RESPONSE REGULATOR receiver
F3X89_RS29275	COG1192	Involved in chromosome partitioning
F3X89_RS29285	COG3843	relaxase mobilization nuclease domain protein
F3X89_RS29290	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
F3X89_RS29295	COG3505	Type IV secretory pathway VirD4
F3X89_RS29330	COG0747	negative chemotaxis
F3X89_RS29350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_RS29355	COG0584	glycerophosphoryl diester phosphodiesterase