locus-tag	class	description
GSF67_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GSF67_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GSF67_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GSF67_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GSF67_RS00025	COG1420	regulation of RNA biosynthetic process
GSF67_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GSF67_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GSF67_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GSF67_RS00050	COG1137	ATPase activity
GSF67_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GSF67_RS00065	COG0616	signal peptide processing
GSF67_RS00070	COG0776	regulation of translation
GSF67_RS00080	COG0116	Belongs to the methyltransferase superfamily
GSF67_RS00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GSF67_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GSF67_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GSF67_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GSF67_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GSF67_RS00115	COG0728	peptidoglycan biosynthetic process
GSF67_RS00120	COG0346	lactoylglutathione lyase activity
GSF67_RS00125	COG0180	Tryptophanyl-tRNA synthetase
GSF67_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GSF67_RS00140	COG1214	PFAM Peptidase M22, glycoprotease
GSF67_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GSF67_RS00165	COG1702	phosphate starvation-inducible protein PhoH
GSF67_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GSF67_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GSF67_RS00185	COG1396	sequence-specific DNA binding
GSF67_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GSF67_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GSF67_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_RS00210	COG0242	peptide deformylase activity
GSF67_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GSF67_RS00220	COG0101	tRNA pseudouridine synthase activity
GSF67_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GSF67_RS00235	COG2171	N-acyltransferase activity
GSF67_RS00245	COG0840	transmembrane signaling receptor activity
GSF67_RS00255	COG0071	Belongs to the small heat shock protein (HSP20) family
GSF67_RS00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GSF67_RS00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GSF67_RS00295	COG0706	membrane insertase activity
GSF67_RS00300	COG0594	ribonuclease P activity
GSF67_RS00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GSF67_RS00310	COG0840	transmembrane signaling receptor activity
GSF67_RS00325	COG2226	methyltransferase
GSF67_RS00330	COG3842	ATPase activity
GSF67_RS00335	COG1175	transmembrane transport
GSF67_RS00340	COG0395	ABC-type sugar transport system, permease component
GSF67_RS00355	COG0427	acetyl-CoA hydrolase
GSF67_RS00365	COG3938	Belongs to the proline racemase family
GSF67_RS00370	COG0418	dihydroorotase activity
GSF67_RS00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GSF67_RS00395	COG0166	Belongs to the GPI family
GSF67_RS00400	COG0318	PFAM AMP-dependent synthetase and ligase
GSF67_RS00405	COG3842	ATPase activity
GSF67_RS00410	COG1840	ABC-type Fe3 transport system, periplasmic component
GSF67_RS00415	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GSF67_RS00420	COG4774	siderophore transport
GSF67_RS00460	COG2326	polyphosphate kinase activity
GSF67_RS00465	COG5002	protein histidine kinase activity
GSF67_RS00470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GSF67_RS00475	COG0573	inorganic phosphate transmembrane transporter activity
GSF67_RS00485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GSF67_RS00490	COG0704	Plays a role in the regulation of phosphate uptake
GSF67_RS00495	COG0745	RESPONSE REGULATOR receiver
GSF67_RS00510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GSF67_RS00515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GSF67_RS00525	COG2967	ApaG domain
GSF67_RS00535	COG0717	Belongs to the dCTP deaminase family
GSF67_RS00545	COG0582	viral genome integration into host DNA
GSF67_RS00560	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSF67_RS00585	COG3501	Rhs element vgr protein
GSF67_RS00660	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GSF67_RS00680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GSF67_RS00735	COG0167	dihydroorotate dehydrogenase activity
GSF67_RS00750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GSF67_RS00770	COG1959	2 iron, 2 sulfur cluster binding
GSF67_RS00775	COG1201	RNA secondary structure unwinding
GSF67_RS00795	COG0730	response to heat
GSF67_RS00805	COG1960	acyl-CoA dehydrogenase activity
GSF67_RS00810	COG0183	Belongs to the thiolase family
GSF67_RS00815	COG1250	3-hydroxyacyl-CoA dehydrogenase
GSF67_RS00815	COG1024	Enoyl-CoA hydratase
GSF67_RS00835	COG1320	monovalent cation:proton antiporter activity
GSF67_RS00840	COG2212	antiporter activity
GSF67_RS00845	COG1863	multisubunit Na H antiporter MnhE subunit
GSF67_RS00850	COG0651	ATP synthesis coupled electron transport
GSF67_RS00855	COG1006	Multisubunit Na H antiporter MnhC subunit
GSF67_RS00860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GSF67_RS00860	COG2111	Na H antiporter
GSF67_RS00870	COG0840	transmembrane signaling receptor activity
GSF67_RS00880	COG0745	RESPONSE REGULATOR receiver
GSF67_RS00885	COG2198	Histidine kinase
GSF67_RS00885	COG0643	Histidine kinase
GSF67_RS00890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GSF67_RS00895	COG2201	protein-glutamate methylesterase activity
GSF67_RS00900	COG0745	RESPONSE REGULATOR receiver
GSF67_RS00905	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GSF67_RS00915	COG1766	The M ring may be actively involved in energy transduction
GSF67_RS00920	COG2771	luxR family
GSF67_RS00930	COG2972	Histidine kinase
GSF67_RS00930	COG0840	transmembrane signaling receptor activity
GSF67_RS00935	COG2205	protein histidine kinase activity
GSF67_RS00935	COG2198	Histidine kinase
GSF67_RS00935	COG0784	Response regulator, receiver
GSF67_RS00945	COG1970	mechanosensitive ion channel activity
GSF67_RS00950	COG0436	Aminotransferase
GSF67_RS00965	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GSF67_RS00970	COG0424	maF-like protein
GSF67_RS00975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GSF67_RS00985	COG5328	Belongs to the UPF0262 family
GSF67_RS00990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GSF67_RS01000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GSF67_RS01330	COG1338	Plays a role in the flagellum-specific transport system
GSF67_RS01340	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GSF67_RS01350	COG1706	bacterial-type flagellum-dependent cell motility
GSF67_RS01355	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GSF67_RS01360	COG4786	Flagellar basal body rod
GSF67_RS01365	COG1677	Flagellar hook-basal body complex protein FliE
GSF67_RS01370	COG1558	bacterial-type flagellum-dependent cell motility
GSF67_RS01375	COG1815	bacterial-type flagellum-dependent cell motility
GSF67_RS01385	COG1157	protein secretion by the type III secretion system
GSF67_RS01390	COG4786	Flagellar basal body rod
GSF67_RS01400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GSF67_RS01405	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GSF67_RS01410	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GSF67_RS01415	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GSF67_RS01420	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GSF67_RS01440	COG1360	Flagellar Motor Protein
GSF67_RS01465	COG1749	Flagellar hook protein flgE
GSF67_RS01485	COG5443	negative regulation of bacterial-type flagellum assembly
GSF67_RS01490	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GSF67_RS01500	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GSF67_RS01540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GSF67_RS01545	COG1609	Transcriptional regulator
GSF67_RS01550	COG1653	transport
GSF67_RS01555	COG1175	transmembrane transport
GSF67_RS01560	COG0395	ABC-type sugar transport system, permease component
GSF67_RS01565	COG0366	Alpha amylase catalytic
GSF67_RS01570	COG3842	ATPase activity
GSF67_RS01585	COG0129	dihydroxy-acid dehydratase activity
GSF67_RS01590	COG0363	glucosamine-6-phosphate deaminase activity
GSF67_RS01595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GSF67_RS01600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS01610	COG2081	HI0933 family
GSF67_RS01625	COG2224	Isocitrate lyase
GSF67_RS01640	COG3842	ATPase activity
GSF67_RS01645	COG1176	ABC-type spermidine putrescine transport system, permease component I
GSF67_RS01650	COG1177	transmembrane transport
GSF67_RS01660	COG2205	protein histidine kinase activity
GSF67_RS01670	COG0248	Ppx GppA phosphatase
GSF67_RS01675	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GSF67_RS01680	COG0477	Major facilitator Superfamily
GSF67_RS01725	COG0521	Mo-molybdopterin cofactor biosynthetic process
GSF67_RS01730	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GSF67_RS01740	COG0142	geranyltranstransferase activity
GSF67_RS01765	COG0752	glycyl-tRNA synthetase alpha subunit
GSF67_RS01775	COG1704	LemA family
GSF67_RS01780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GSF67_RS01790	COG0751	glycine-tRNA ligase activity
GSF67_RS01795	COG1683	Conserved Protein
GSF67_RS01800	COG0840	transmembrane signaling receptor activity
GSF67_RS01810	COG0151	Belongs to the GarS family
GSF67_RS01815	COG2183	response to ionizing radiation
GSF67_RS01820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GSF67_RS01830	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GSF67_RS01845	COG0583	DNA-binding transcription factor activity
GSF67_RS01865	COG0306	phosphate transporter
GSF67_RS01875	COG0561	phosphatase activity
GSF67_RS01880	COG0438	transferase activity, transferring glycosyl groups
GSF67_RS01885	COG2186	Transcriptional regulator
GSF67_RS01895	COG0583	DNA-binding transcription factor activity
GSF67_RS01900	COG0277	FAD linked oxidase domain protein
GSF67_RS01905	COG0277	FAD linked oxidase domain protein
GSF67_RS01910	COG0247	lactate metabolic process
GSF67_RS01920	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_RS01925	COG2818	Glycosylase
GSF67_RS01935	COG2855	membrane
GSF67_RS01940	COG0583	DNA-binding transcription factor activity
GSF67_RS01960	COG0124	histidyl-tRNA synthetase
GSF67_RS01970	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GSF67_RS01975	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GSF67_RS01980	COG2259	Doxx family
GSF67_RS01990	COG0459	protein refolding
GSF67_RS01995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GSF67_RS02005	COG0196	riboflavin kinase activity
GSF67_RS02010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GSF67_RS02020	COG0590	tRNA wobble adenosine to inosine editing
GSF67_RS02025	COG1187	pseudouridine synthase activity
GSF67_RS02030	COG0742	ribosomal rna small subunit methyltransferase
GSF67_RS02035	COG1752	Esterase of the alpha-beta hydrolase superfamily
GSF67_RS02045	COG0312	modulator of DNA gyrase
GSF67_RS02050	COG0483	inositol monophosphate 1-phosphatase activity
GSF67_RS02060	COG1519	Transferase
GSF67_RS02070	COG1663	tetraacyldisaccharide 4'-kinase activity
GSF67_RS02080	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GSF67_RS02090	COG5001	Diguanylate cyclase
GSF67_RS02090	COG3300	MHYT domain
GSF67_RS02095	COG3386	PFAM SMP-30 Gluconolaconase
GSF67_RS02100	COG0800	Aldolase
GSF67_RS02105	COG3734	2-keto-3-deoxy-galactonokinase
GSF67_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS02120	COG2197	response regulator
GSF67_RS02125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSF67_RS02135	COG0598	Magnesium transport protein CorA
GSF67_RS02140	COG3158	transport of potassium into the cell
GSF67_RS02155	COG0356	it plays a direct role in the translocation of protons across the membrane
GSF67_RS02165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GSF67_RS02170	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GSF67_RS02185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GSF67_RS02205	COG0009	L-threonylcarbamoyladenylate synthase
GSF67_RS02215	COG4638	Rieske (2fe-2S)
GSF67_RS02240	COG1960	acyl-CoA dehydrogenase activity
GSF67_RS02255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GSF67_RS02260	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GSF67_RS02265	COG0840	transmembrane signaling receptor activity
GSF67_RS02275	COG1522	sequence-specific DNA binding
GSF67_RS02305	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GSF67_RS02310	COG1741	Belongs to the pirin family
GSF67_RS02315	COG1722	exodeoxyribonuclease VII activity
GSF67_RS02320	COG0123	including yeast histone deacetylase and acetoin utilization protein
GSF67_RS02325	COG1268	BioY protein
GSF67_RS02330	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GSF67_RS02335	COG1122	ATPase activity
GSF67_RS02340	COG3214	Protein conserved in bacteria
GSF67_RS02345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GSF67_RS02345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GSF67_RS02350	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GSF67_RS02370	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GSF67_RS02385	COG0259	pyridoxamine-phosphate oxidase activity
GSF67_RS02400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF67_RS02410	COG0312	modulator of DNA gyrase
GSF67_RS02425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GSF67_RS02430	COG0109	protoheme IX farnesyltransferase activity
GSF67_RS02435	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GSF67_RS02450	COG3346	SURF1 family
GSF67_RS02455	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GSF67_RS02460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GSF67_RS02465	COG0328	RNA-DNA hybrid ribonuclease activity
GSF67_RS02480	COG0678	peroxiredoxin activity
GSF67_RS02480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GSF67_RS02490	COG1678	Uncharacterized ACR, COG1678
GSF67_RS02510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSF67_RS02515	COG0612	Peptidase, M16
GSF67_RS02540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF67_RS02545	COG1802	Transcriptional regulator
GSF67_RS02560	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GSF67_RS02570	COG3609	addiction module antidote protein, CC2985 family
GSF67_RS02585	COG1194	a g-specific adenine glycosylase
GSF67_RS02595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GSF67_RS02600	COG1196	nuclear chromosome segregation
GSF67_RS02605	COG2514	catechol 2,3-dioxygenase activity
GSF67_RS02610	COG0574	Belongs to the PEP-utilizing enzyme family
GSF67_RS02610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GSF67_RS02645	COG0579	oxidoreductase
GSF67_RS02660	COG2895	sulfate adenylyltransferase (ATP) activity
GSF67_RS02665	COG0175	sulfate reduction
GSF67_RS02670	COG0175	sulfate reduction
GSF67_RS02675	COG1959	2 iron, 2 sulfur cluster binding
GSF67_RS02680	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GSF67_RS02685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GSF67_RS02690	COG4208	sulfate ABC transporter
GSF67_RS02695	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GSF67_RS02705	COG2199	diguanylate cyclase activity
GSF67_RS02705	COG2200	EAL domain
GSF67_RS02705	COG2203	Gaf domain
GSF67_RS02715	COG1309	transcriptional regulator
GSF67_RS02720	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_RS02725	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GSF67_RS02770	COG0477	Major facilitator Superfamily
GSF67_RS02780	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GSF67_RS02780	COG1793	dna ligase
GSF67_RS02800	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_RS02805	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_RS02810	COG1846	Transcriptional regulator
GSF67_RS02815	COG1764	response to oxidative stress
GSF67_RS02830	COG0488	(ABC) transporter
GSF67_RS02865	COG4221	oxidoreductase activity
GSF67_RS02880	COG0433	COG0433 Predicted ATPase
GSF67_RS02890	COG1733	regulation of RNA biosynthetic process
GSF67_RS02895	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GSF67_RS02905	COG1280	lysine exporter protein (LysE YggA)
GSF67_RS02910	COG0656	L-ascorbic acid biosynthetic process
GSF67_RS02915	COG3781	membrane
GSF67_RS02920	COG2378	regulation of single-species biofilm formation
GSF67_RS02930	COG4106	trans-aconitate 2-methyltransferase activity
GSF67_RS02935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GSF67_RS02940	COG0840	transmembrane signaling receptor activity
GSF67_RS02945	COG0583	DNA-binding transcription factor activity
GSF67_RS02960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GSF67_RS02970	COG2378	regulation of single-species biofilm formation
GSF67_RS02980	COG3909	cytochrome
GSF67_RS02985	COG2010	Cytochrome c
GSF67_RS03020	COG0789	Transcriptional regulator
GSF67_RS03045	COG4175	Glycine betaine
GSF67_RS03050	COG4176	ABC-type proline glycine betaine transport system permease component
GSF67_RS03075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_RS03085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GSF67_RS03085	COG2169	Transcriptional regulator
GSF67_RS03095	COG2514	catechol 2,3-dioxygenase activity
GSF67_RS03110	COG1272	protein, Hemolysin III
GSF67_RS03120	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GSF67_RS03130	COG2111	Na H antiporter
GSF67_RS03135	COG1006	Multisubunit Na H antiporter MnhC subunit
GSF67_RS03150	COG2212	antiporter activity
GSF67_RS03155	COG1320	monovalent cation:proton antiporter activity
GSF67_RS03160	COG4957	zinc ion binding
GSF67_RS03175	COG2166	iron-sulfur cluster assembly
GSF67_RS03185	COG2205	protein histidine kinase activity
GSF67_RS03240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GSF67_RS03245	COG2983	Belongs to the UPF0260 family
GSF67_RS03280	COG2337	Toxic component of a toxin-antitoxin (TA) module
GSF67_RS03290	COG2814	Major facilitator Superfamily
GSF67_RS03300	COG1621	beta-fructofuranosidase activity
GSF67_RS03305	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GSF67_RS03355	COG4695	Portal protein
GSF67_RS03445	COG0745	RESPONSE REGULATOR receiver
GSF67_RS03450	COG5002	protein histidine kinase activity
GSF67_RS03460	COG4235	cytochrome complex assembly
GSF67_RS03465	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GSF67_RS03470	COG1138	Cytochrome C-type biogenesis protein
GSF67_RS03475	COG3088	subunit of a heme lyase
GSF67_RS03480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GSF67_RS03490	COG2205	protein histidine kinase activity
GSF67_RS03495	COG3011	Protein conserved in bacteria
GSF67_RS03505	COG3713	MltA-interacting MipA family protein
GSF67_RS03510	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GSF67_RS03515	COG2202	Pas domain
GSF67_RS03515	COG2205	protein histidine kinase activity
GSF67_RS03525	COG0308	aminopeptidase N
GSF67_RS03530	COG0697	spore germination
GSF67_RS03545	COG0443	Heat shock 70 kDa protein
GSF67_RS03555	COG0300	oxidoreductase activity
GSF67_RS03585	COG0604	alcohol dehydrogenase
GSF67_RS03590	COG1733	regulation of RNA biosynthetic process
GSF67_RS03595	COG1968	undecaprenyl-diphosphatase activity
GSF67_RS03600	COG2239	Acts as a magnesium transporter
GSF67_RS03605	COG2814	Major facilitator Superfamily
GSF67_RS03635	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GSF67_RS03665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GSF67_RS03715	COG0741	lytic transglycosylase activity
GSF67_RS03725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_RS03730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GSF67_RS03735	COG0840	transmembrane signaling receptor activity
GSF67_RS03745	COG1758	RNA polymerase activity
GSF67_RS03765	COG0736	holo-[acyl-carrier-protein] synthase activity
GSF67_RS03770	COG0681	Belongs to the peptidase S26 family
GSF67_RS03775	COG0571	ribonuclease III activity
GSF67_RS03780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GSF67_RS03785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GSF67_RS03790	COG0784	Response regulator, receiver
GSF67_RS03795	COG1381	Involved in DNA repair and RecF pathway recombination
GSF67_RS03805	COG2226	methyltransferase
GSF67_RS03815	COG1418	mRNA catabolic process
GSF67_RS03825	COG0346	lactoylglutathione lyase activity
GSF67_RS03835	COG1116	anion transmembrane transporter activity
GSF67_RS03840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_RS03845	COG3443	Belongs to the bacterial solute-binding protein 9 family
GSF67_RS03850	COG0668	transmembrane transport
GSF67_RS03860	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GSF67_RS03885	COG1051	belongs to the nudix hydrolase family
GSF67_RS03890	COG1742	UPF0060 membrane protein
GSF67_RS03905	COG1183	phosphatidylcholine synthase activity
GSF67_RS03910	COG0688	phosphatidylethanolamine metabolic process
GSF67_RS03915	COG5265	(ABC) transporter
GSF67_RS03955	COG2852	Protein conserved in bacteria
GSF67_RS03960	COG0215	cysteine-tRNA ligase activity
GSF67_RS03965	COG4221	oxidoreductase activity
GSF67_RS03970	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GSF67_RS03975	COG1286	toxin biosynthetic process
GSF67_RS03995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GSF67_RS04005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GSF67_RS04015	COG5265	(ABC) transporter
GSF67_RS04020	COG0305	Participates in initiation and elongation during chromosome replication
GSF67_RS04040	COG0359	binds to the 23S rRNA
GSF67_RS04050	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GSF67_RS04055	COG0360	Binds together with S18 to 16S ribosomal RNA
GSF67_RS04060	COG0667	Aldo Keto reductase
GSF67_RS04065	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GSF67_RS04075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GSF67_RS04080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GSF67_RS04085	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GSF67_RS04090	COG1561	YicC-like family, N-terminal region
GSF67_RS04095	COG0194	GDP metabolic process
GSF67_RS04100	COG0400	carboxylic ester hydrolase activity
GSF67_RS04105	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GSF67_RS04110	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GSF67_RS04120	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GSF67_RS04135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GSF67_RS04155	COG5001	Diguanylate cyclase
GSF67_RS04155	COG3300	MHYT domain
GSF67_RS04160	COG4191	Histidine kinase
GSF67_RS04175	COG0488	(ABC) transporter
GSF67_RS04180	COG3706	GGDEF domain
GSF67_RS04190	COG0105	UTP biosynthetic process
GSF67_RS04210	COG0314	molybdopterin synthase activity
GSF67_RS04215	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GSF67_RS04220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GSF67_RS04225	COG0322	excinuclease ABC activity
GSF67_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS04240	COG0625	glutathione transferase activity
GSF67_RS04255	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GSF67_RS04260	COG0243	molybdopterin cofactor binding
GSF67_RS04275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GSF67_RS04280	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GSF67_RS04285	COG0628	permease
GSF67_RS04295	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GSF67_RS04300	COG0248	Ppx GppA phosphatase
GSF67_RS04325	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GSF67_RS04335	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GSF67_RS04340	COG0477	Major facilitator Superfamily
GSF67_RS04345	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GSF67_RS04355	COG4452	Inner membrane protein CreD
GSF67_RS04360	COG0659	secondary active sulfate transmembrane transporter activity
GSF67_RS04370	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GSF67_RS04380	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GSF67_RS04390	COG0113	porphobilinogen synthase activity
GSF67_RS04410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GSF67_RS04415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GSF67_RS04420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GSF67_RS04420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GSF67_RS04430	COG1280	lysine exporter protein (LysE YggA)
GSF67_RS04435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GSF67_RS04440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GSF67_RS04445	COG2814	Major facilitator Superfamily
GSF67_RS04450	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GSF67_RS04470	COG0416	fatty acid biosynthetic process
GSF67_RS04475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GSF67_RS04480	COG0776	regulation of translation
GSF67_RS04515	COG0601	transmembrane transport
GSF67_RS04520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS04525	COG0444	Belongs to the ABC transporter superfamily
GSF67_RS04545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GSF67_RS04550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GSF67_RS04565	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GSF67_RS04570	COG0583	DNA-binding transcription factor activity
GSF67_RS04575	COG0737	Belongs to the 5'-nucleotidase family
GSF67_RS04600	COG2897	thiosulfate sulfurtransferase activity
GSF67_RS04615	COG0415	Belongs to the DNA photolyase family
GSF67_RS04625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GSF67_RS04655	COG3932	Exopolysaccharide synthesis, ExoD
GSF67_RS04735	COG1612	heme a metabolic process
GSF67_RS04745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GSF67_RS04750	COG0010	Belongs to the arginase family
GSF67_RS04755	COG1396	sequence-specific DNA binding
GSF67_RS04760	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GSF67_RS04765	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GSF67_RS04770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GSF67_RS04780	COG1832	CoA-binding protein
GSF67_RS04805	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS04810	COG2124	cytochrome p450
GSF67_RS04815	COG2199	diguanylate cyclase activity
GSF67_RS04820	COG0740	serine-type endopeptidase activity
GSF67_RS04825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GSF67_RS04830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GSF67_RS04840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GSF67_RS04870	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSF67_RS04875	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSF67_RS04880	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSF67_RS04890	COG0649	NAD binding
GSF67_RS04900	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GSF67_RS04905	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GSF67_RS04915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GSF67_RS04920	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSF67_RS04930	COG0713	ATP synthesis coupled electron transport
GSF67_RS04945	COG1007	ATP synthesis coupled electron transport
GSF67_RS04965	COG0442	prolyl-tRNA aminoacylation
GSF67_RS04975	COG1136	(ABC) transporter
GSF67_RS04990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GSF67_RS05000	COG0784	Response regulator, receiver
GSF67_RS05010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GSF67_RS05015	COG0477	Major facilitator Superfamily
GSF67_RS05030	COG0557	exoribonuclease II activity
GSF67_RS05035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GSF67_RS05045	COG0758	DNA mediated transformation
GSF67_RS05050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GSF67_RS05060	COG0540	Belongs to the ATCase OTCase family
GSF67_RS05070	COG1960	acyl-CoA dehydrogenase activity
GSF67_RS05075	COG0456	acetyltransferase
GSF67_RS05105	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GSF67_RS05110	COG2824	Alkylphosphonate utilization operon protein PhnA
GSF67_RS05115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GSF67_RS05120	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GSF67_RS05125	COG0154	amidase activity
GSF67_RS05130	COG0456	acetyltransferase
GSF67_RS05135	COG3811	Belongs to the UPF0386 family
GSF67_RS05150	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GSF67_RS05160	COG0456	acetyltransferase
GSF67_RS05175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GSF67_RS05180	COG0439	Biotin carboxylase
GSF67_RS05185	COG0511	ligase activity, forming carbon-carbon bonds
GSF67_RS05190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GSF67_RS05200	COG0436	Aminotransferase
GSF67_RS05220	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS05225	COG1530	ribonuclease E activity
GSF67_RS05240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GSF67_RS05260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GSF67_RS05265	COG0384	phenazine biosynthesis protein PhzF
GSF67_RS05285	COG0633	Ferredoxin
GSF67_RS05295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GSF67_RS05300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GSF67_RS05305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GSF67_RS05315	COG3768	UPF0283 membrane protein
GSF67_RS05320	COG3106	COG3106 Predicted ATPase
GSF67_RS05350	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GSF67_RS05380	COG0537	adenosine 5'-monophosphoramidase activity
GSF67_RS05405	COG0052	Belongs to the universal ribosomal protein uS2 family
GSF67_RS05410	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GSF67_RS05415	COG0528	UMP kinase activity
GSF67_RS05420	COG0233	cytoplasmic translational termination
GSF67_RS05425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GSF67_RS05435	COG0750	zinc metalloprotease
GSF67_RS05440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GSF67_RS05445	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GSF67_RS05450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GSF67_RS05455	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GSF67_RS05460	COG3494	Protein of unknown function (DUF1009)
GSF67_RS05465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GSF67_RS05470	COG2186	Transcriptional regulator
GSF67_RS05480	COG0765	amino acid transport
GSF67_RS05495	COG0372	Belongs to the citrate synthase family
GSF67_RS05510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GSF67_RS05515	COG4598	ABC transporter
GSF67_RS05520	COG0765	amino acid transport
GSF67_RS05530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS05535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_RS05540	COG3842	ATPase activity
GSF67_RS05545	COG0395	ABC-type sugar transport system, permease component
GSF67_RS05555	COG2182	Extracellular solute-binding protein
GSF67_RS05565	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_RS05570	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS05575	COG1063	alcohol dehydrogenase
GSF67_RS05580	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GSF67_RS05600	COG0683	leucine binding
GSF67_RS05605	COG1960	acyl-CoA dehydrogenase activity
GSF67_RS05620	COG1024	Enoyl-CoA hydratase
GSF67_RS05635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GSF67_RS05655	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GSF67_RS05660	COG0148	phosphopyruvate hydratase activity
GSF67_RS05670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GSF67_RS05675	COG0508	dehydrogenase complex catalyzes the overall conversion of
GSF67_RS05675	COG0022	dehydrogenase e1 component
GSF67_RS05685	COG0508	dehydrogenase complex catalyzes the overall conversion of
GSF67_RS05695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GSF67_RS05705	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GSF67_RS05710	COG0697	spore germination
GSF67_RS05730	COG2867	negative regulation of translational initiation
GSF67_RS05735	COG1546	Belongs to the CinA family
GSF67_RS05740	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GSF67_RS05740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GSF67_RS05750	COG3852	Histidine kinase
GSF67_RS05755	COG2204	response regulator
GSF67_RS05760	COG5000	phosphorelay sensor kinase activity
GSF67_RS05765	COG2204	response regulator
GSF67_RS05770	COG0569	domain protein
GSF67_RS05775	COG1923	regulation of RNA biosynthetic process
GSF67_RS05780	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GSF67_RS05785	COG3956	TIGRFAM MazG family protein
GSF67_RS05795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GSF67_RS05795	COG1648	precorrin-2 dehydrogenase activity
GSF67_RS05810	COG0275	rRNA processing
GSF67_RS05835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GSF67_RS05835	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GSF67_RS05840	COG0509	glycine decarboxylation via glycine cleavage system
GSF67_RS05845	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GSF67_RS05870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GSF67_RS05880	COG0546	phosphoglycolate phosphatase activity
GSF67_RS05895	COG0251	oxidation-reduction process
GSF67_RS05900	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GSF67_RS05910	COG1671	Belongs to the UPF0178 family
GSF67_RS05920	COG0450	alkyl hydroperoxide reductase
GSF67_RS05960	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GSF67_RS05965	COG2801	Transposase and inactivated derivatives
GSF67_RS05970	COG0431	NADPH-dependent FMN reductase
GSF67_RS06000	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GSF67_RS06000	COG0321	lipoyl(octanoyl) transferase activity
GSF67_RS06005	COG0084	hydrolase, TatD family'
GSF67_RS06010	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSF67_RS06020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GSF67_RS06075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GSF67_RS06080	COG2095	MarC family integral membrane protein
GSF67_RS06085	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GSF67_RS06085	COG0517	IMP dehydrogenase activity
GSF67_RS06085	COG0617	tRNA 3'-terminal CCA addition
GSF67_RS06095	COG3609	addiction module antidote protein, CC2985 family
GSF67_RS06100	COG0629	single-stranded DNA binding
GSF67_RS06105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GSF67_RS06115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GSF67_RS06120	COG0179	Fumarylacetoacetate (FAA) hydrolase
GSF67_RS06135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GSF67_RS06140	COG1121	(ABC) transporter
GSF67_RS06160	COG0667	Aldo Keto reductase
GSF67_RS06170	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GSF67_RS06240	COG0668	transmembrane transport
GSF67_RS06265	COG2239	Acts as a magnesium transporter
GSF67_RS06270	COG0243	molybdopterin cofactor binding
GSF67_RS06280	COG0242	peptide deformylase activity
GSF67_RS06305	COG0321	lipoyl(octanoyl) transferase activity
GSF67_RS06310	COG1064	alcohol dehydrogenase
GSF67_RS06340	COG1862	Preprotein translocase
GSF67_RS06365	COG2124	cytochrome p450
GSF67_RS06380	COG0596	Alpha beta hydrolase
GSF67_RS06390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GSF67_RS06395	COG0626	cystathionine gamma-synthase activity
GSF67_RS06400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS06405	COG4597	amino acid ABC transporter
GSF67_RS06410	COG0765	amino acid transport
GSF67_RS06415	COG1126	abc transporter atp-binding protein
GSF67_RS06430	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GSF67_RS06445	COG0436	Aminotransferase
GSF67_RS06475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GSF67_RS06485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GSF67_RS06490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GSF67_RS06495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GSF67_RS06510	COG3243	poly(R)-hydroxyalkanoic acid synthase
GSF67_RS06515	COG1489	DNA binding
GSF67_RS06520	COG0024	Methionine aminopeptidase
GSF67_RS06570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSF67_RS06685	COG2963	transposase activity
GSF67_RS06695	COG4372	Transposase
GSF67_RS06745	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GSF67_RS06765	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GSF67_RS06770	COG0546	phosphoglycolate phosphatase activity
GSF67_RS06785	COG0114	fumarate hydratase activity
GSF67_RS06795	COG0504	CTP synthase activity
GSF67_RS06805	COG0149	triose-phosphate isomerase activity
GSF67_RS06815	COG0187	DNA topoisomerase II activity
GSF67_RS06880	COG0326	Molecular chaperone. Has ATPase activity
GSF67_RS06890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GSF67_RS06915	COG1309	transcriptional regulator
GSF67_RS06930	COG0740	serine-type endopeptidase activity
GSF67_RS06940	COG0640	Transcriptional regulator
GSF67_RS06945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GSF67_RS06950	COG0745	RESPONSE REGULATOR receiver
GSF67_RS06960	COG3264	Mechanosensitive ion channel
GSF67_RS06960	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GSF67_RS07025	COG1127	ABC transporter
GSF67_RS07030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GSF67_RS07035	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_RS07055	COG0280	phosphate acetyltransferase
GSF67_RS07055	COG0281	malic enzyme
GSF67_RS07065	COG0778	Nitroreductase
GSF67_RS07070	COG0823	Involved in the tonB-independent uptake of proteins
GSF67_RS07080	COG1368	sulfuric ester hydrolase activity
GSF67_RS07100	COG4977	sequence-specific DNA binding
GSF67_RS07115	COG0544	peptidyl-prolyl cis-trans isomerase activity
GSF67_RS07135	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GSF67_RS07140	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GSF67_RS07170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GSF67_RS07170	COG0512	Glutamine amidotransferase of anthranilate synthase
GSF67_RS07175	COG0343	queuine tRNA-ribosyltransferase activity
GSF67_RS07180	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GSF67_RS07195	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GSF67_RS07210	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GSF67_RS07215	COG0134	indole-3-glycerol-phosphate synthase activity
GSF67_RS07220	COG0315	cyclic pyranopterin monophosphate synthase activity
GSF67_RS07225	COG0303	'Molybdopterin
GSF67_RS07230	COG3706	GGDEF domain
GSF67_RS07240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GSF67_RS07240	COG0475	glutathione-regulated potassium exporter activity
GSF67_RS07250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GSF67_RS07255	COG0697	spore germination
GSF67_RS07260	COG2814	Major facilitator Superfamily
GSF67_RS07265	COG0746	molybdenum cofactor guanylyltransferase activity
GSF67_RS07270	COG1763	Mo-molybdopterin cofactor biosynthetic process
GSF67_RS07275	COG0739	heme binding
GSF67_RS07280	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GSF67_RS07285	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GSF67_RS07290	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GSF67_RS07295	COG0805	protein transport
GSF67_RS07300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GSF67_RS07305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GSF67_RS07310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GSF67_RS07315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GSF67_RS07320	COG1472	Belongs to the glycosyl hydrolase 3 family
GSF67_RS07330	COG0018	arginyl-trna synthetase
GSF67_RS07335	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GSF67_RS07340	COG0316	Belongs to the HesB IscA family
GSF67_RS07350	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GSF67_RS07365	COG0525	valine-tRNA ligase activity
GSF67_RS07375	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GSF67_RS07405	COG0655	NAD(P)H dehydrogenase (quinone) activity
GSF67_RS07410	COG1546	Belongs to the CinA family
GSF67_RS07410	COG1058	Belongs to the CinA family
GSF67_RS07415	COG0589	response to stress
GSF67_RS07420	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GSF67_RS07425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GSF67_RS07440	COG1914	H( )-stimulated, divalent metal cation uptake system
GSF67_RS07450	COG1132	(ABC) transporter
GSF67_RS07455	COG0628	permease
GSF67_RS07475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GSF67_RS07490	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GSF67_RS07500	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GSF67_RS07510	COG0302	gtp cyclohydrolase
GSF67_RS07515	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GSF67_RS07520	COG1752	Esterase of the alpha-beta hydrolase superfamily
GSF67_RS07525	COG0517	IMP dehydrogenase activity
GSF67_RS07525	COG0516	GMP reductase activity
GSF67_RS07555	COG1760	l-serine dehydratase
GSF67_RS07590	COG0583	DNA-binding transcription factor activity
GSF67_RS07605	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GSF67_RS07605	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GSF67_RS07610	COG0347	Belongs to the P(II) protein family
GSF67_RS07615	COG0174	glutamine synthetase
GSF67_RS07645	COG0697	spore germination
GSF67_RS07655	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GSF67_RS07665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GSF67_RS07695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GSF67_RS07700	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GSF67_RS07705	COG2186	Transcriptional regulator
GSF67_RS07725	COG1129	ABC transporter
GSF67_RS07730	COG1183	phosphatidylcholine synthase activity
GSF67_RS07735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GSF67_RS07740	COG0679	Auxin Efflux Carrier
GSF67_RS07745	COG0785	Cytochrome C biogenesis protein
GSF67_RS07775	COG1278	Cold shock
GSF67_RS07915	COG0433	COG0433 Predicted ATPase
GSF67_RS07945	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GSF67_RS07970	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GSF67_RS08005	COG1475	DNA binding
GSF67_RS08030	COG3750	Belongs to the UPF0335 family
GSF67_RS08235	COG0582	viral genome integration into host DNA
GSF67_RS08250	COG2267	carboxylic ester hydrolase activity
GSF67_RS08265	COG1136	(ABC) transporter
GSF67_RS08265	COG0577	efflux transmembrane transporter activity
GSF67_RS08270	COG1136	(ABC) transporter
GSF67_RS08270	COG0577	efflux transmembrane transporter activity
GSF67_RS08285	COG2151	metal-sulfur cluster biosynthetic enzyme
GSF67_RS08290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GSF67_RS08295	COG0719	Fe-S assembly protein
GSF67_RS08300	COG0396	ATPase activity
GSF67_RS08310	COG0719	Fe-S assembly protein
GSF67_RS08315	COG1104	cysteine desulfurase activity
GSF67_RS08320	COG2945	thiolester hydrolase activity
GSF67_RS08325	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GSF67_RS08330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GSF67_RS08340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GSF67_RS08345	COG2833	Protein of unknown function (DUF455)
GSF67_RS08350	COG0739	heme binding
GSF67_RS08355	COG0513	Belongs to the DEAD box helicase family
GSF67_RS08385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GSF67_RS08395	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GSF67_RS08400	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GSF67_RS08405	COG0047	phosphoribosylformylglycinamidine synthase activity
GSF67_RS08420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSF67_RS08430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GSF67_RS08450	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GSF67_RS08455	COG2814	Major facilitator Superfamily
GSF67_RS08460	COG0483	inositol monophosphate 1-phosphatase activity
GSF67_RS08465	COG0483	inositol monophosphate 1-phosphatase activity
GSF67_RS08470	COG0037	tRNA processing
GSF67_RS08475	COG2066	Belongs to the glutaminase family
GSF67_RS08480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GSF67_RS08485	COG0861	Integral membrane protein TerC family
GSF67_RS08500	COG1280	lysine exporter protein (LysE YggA)
GSF67_RS08510	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GSF67_RS08515	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GSF67_RS08525	COG0538	isocitrate dehydrogenase activity
GSF67_RS08540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GSF67_RS08545	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GSF67_RS08550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_RS08555	COG2313	pseudouridylate synthase activity
GSF67_RS08565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS08570	COG4215	(ABC) transporter
GSF67_RS08580	COG5425	PFAM Usg family protein
GSF67_RS08590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSF67_RS08595	COG1522	sequence-specific DNA binding
GSF67_RS08600	COG1573	uracil-dna glycosylase
GSF67_RS08610	COG2202	Pas domain
GSF67_RS08610	COG2205	protein histidine kinase activity
GSF67_RS08620	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GSF67_RS08625	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GSF67_RS08640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GSF67_RS08645	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS08650	COG1129	ABC transporter
GSF67_RS08660	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS08665	COG3959	Transketolase, thiamine diphosphate binding domain
GSF67_RS08670	COG3958	Transketolase
GSF67_RS08675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GSF67_RS08680	COG2390	Transcriptional regulator
GSF67_RS08690	COG0842	Transport permease protein
GSF67_RS08695	COG1131	(ABC) transporter
GSF67_RS08720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GSF67_RS08725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GSF67_RS08740	COG0129	dihydroxy-acid dehydratase activity
GSF67_RS08745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GSF67_RS08750	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GSF67_RS08760	COG3739	integral membrane protein
GSF67_RS08765	COG0203	ribosomal protein L17
GSF67_RS08770	COG0202	RNA polymerase activity
GSF67_RS08775	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GSF67_RS08780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GSF67_RS08785	COG0563	adenylate kinase activity
GSF67_RS08790	COG0201	protein transport
GSF67_RS08795	COG0200	Binds to the 23S rRNA
GSF67_RS08800	COG1841	ribosomal large subunit assembly
GSF67_RS08805	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GSF67_RS08810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GSF67_RS08815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GSF67_RS08820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GSF67_RS08825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GSF67_RS08830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GSF67_RS08835	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GSF67_RS08840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GSF67_RS08845	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GSF67_RS08850	COG0255	Belongs to the universal ribosomal protein uL29 family
GSF67_RS08855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GSF67_RS08860	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GSF67_RS08865	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GSF67_RS08870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GSF67_RS08875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GSF67_RS08880	COG0089	rRNA binding
GSF67_RS08885	COG0088	Forms part of the polypeptide exit tunnel
GSF67_RS08890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GSF67_RS08895	COG0051	transcription antitermination factor activity, RNA binding
GSF67_RS08900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GSF67_RS08905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GSF67_RS08910	COG0049	tRNA binding
GSF67_RS08915	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GSF67_RS08935	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GSF67_RS08940	COG0085	RNA polymerase activity
GSF67_RS08945	COG0222	ribosome binding
GSF67_RS08950	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GSF67_RS08955	COG0081	regulation of translation
GSF67_RS08960	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GSF67_RS08970	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GSF67_RS08980	COG1086	Polysaccharide biosynthesis protein
GSF67_RS08985	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GSF67_RS08990	COG0861	Integral membrane protein TerC family
GSF67_RS08995	COG3895	Periplasmic Protein
GSF67_RS09015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GSF67_RS09035	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GSF67_RS09070	COG0784	Response regulator, receiver
GSF67_RS09070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS09070	COG2205	protein histidine kinase activity
GSF67_RS09070	COG2198	Histidine kinase
GSF67_RS09075	COG0784	Response regulator, receiver
GSF67_RS09080	COG3920	Histidine kinase
GSF67_RS09080	COG2202	Pas domain
GSF67_RS09085	COG0784	Response regulator, receiver
GSF67_RS09090	COG4251	negative regulation of phosphorylation
GSF67_RS09105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GSF67_RS09135	COG2910	NAD(P)H-binding
GSF67_RS09140	COG1733	regulation of RNA biosynthetic process
GSF67_RS09145	COG0556	nucleotide-excision repair
GSF67_RS09150	COG2382	esterase
GSF67_RS09170	COG0484	heat shock protein binding
GSF67_RS09215	COG3706	GGDEF domain
GSF67_RS09225	COG3842	ATPase activity
GSF67_RS09235	COG1840	ABC-type Fe3 transport system, periplasmic component
GSF67_RS09240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSF67_RS09255	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GSF67_RS09265	COG2207	Transcriptional regulator
GSF67_RS09270	COG1064	alcohol dehydrogenase
GSF67_RS09275	COG1252	NADH dehydrogenase
GSF67_RS09280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GSF67_RS09285	COG2197	response regulator
GSF67_RS09290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GSF67_RS09320	COG0656	L-ascorbic acid biosynthetic process
GSF67_RS09335	COG0440	acetolactate synthase activity
GSF67_RS09340	COG0028	Belongs to the TPP enzyme family
GSF67_RS09350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GSF67_RS09355	COG3830	Belongs to the UPF0237 family
GSF67_RS09355	COG0560	Phosphoserine phosphatase
GSF67_RS09365	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS09380	COG0330	HflC and HflK could
GSF67_RS09385	COG0330	HflC and HflK could
GSF67_RS09395	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GSF67_RS09435	COG0277	FAD linked oxidase domain protein
GSF67_RS09440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GSF67_RS09495	COG1335	isochorismatase
GSF67_RS09515	COG0006	proline dipeptidase activity
GSF67_RS09525	COG2264	protein methyltransferase activity
GSF67_RS09530	COG1999	signal sequence binding
GSF67_RS09540	COG0835	chemotaxis
GSF67_RS09550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GSF67_RS09555	COG0583	DNA-binding transcription factor activity
GSF67_RS09565	COG1247	-acetyltransferase
GSF67_RS09575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GSF67_RS09580	COG0497	DNA recombination
GSF67_RS09585	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GSF67_RS09595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GSF67_RS09600	COG0849	cell division
GSF67_RS09605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GSF67_RS09610	COG1181	Belongs to the D-alanine--D-alanine ligase family
GSF67_RS09615	COG0477	Major facilitator Superfamily
GSF67_RS09620	COG3300	MHYT domain
GSF67_RS09620	COG5001	Diguanylate cyclase
GSF67_RS09625	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GSF67_RS09630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GSF67_RS09635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GSF67_RS09645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GSF67_RS09650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GSF67_RS09660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GSF67_RS09675	COG0275	rRNA processing
GSF67_RS09680	COG2001	Belongs to the MraZ family
GSF67_RS09685	COG3766	membrane
GSF67_RS09695	COG0754	glutathionylspermidine amidase activity
GSF67_RS09720	COG3023	N-Acetylmuramoyl-L-alanine amidase
GSF67_RS09750	COG4106	trans-aconitate 2-methyltransferase activity
GSF67_RS09770	COG2226	methyltransferase
GSF67_RS09780	COG2267	carboxylic ester hydrolase activity
GSF67_RS09785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GSF67_RS09800	COG0251	oxidation-reduction process
GSF67_RS09815	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_RS09820	COG2814	Major facilitator Superfamily
GSF67_RS09845	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_RS09860	COG0174	glutamine synthetase
GSF67_RS09865	COG0531	amino acid
GSF67_RS09875	COG1737	Transcriptional regulator
GSF67_RS09895	COG3842	ATPase activity
GSF67_RS09955	COG2968	Membrane
GSF67_RS09965	COG0432	Pfam Uncharacterised protein family UPF0047
GSF67_RS09980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GSF67_RS09985	COG0358	DNA primase activity
GSF67_RS10005	COG0505	Belongs to the CarA family
GSF67_RS10010	COG0534	Mate efflux family protein
GSF67_RS10025	COG2321	neutral zinc metallopeptidase
GSF67_RS10040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GSF67_RS10050	COG3706	GGDEF domain
GSF67_RS10065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GSF67_RS10075	COG1522	sequence-specific DNA binding
GSF67_RS10080	COG0492	ferredoxin-NADP+ reductase activity
GSF67_RS10085	COG0583	DNA-binding transcription factor activity
GSF67_RS10095	COG1902	pentaerythritol trinitrate reductase activity
GSF67_RS10120	COG0387	Pfam Sodium calcium exchanger
GSF67_RS10125	COG0436	Aminotransferase
GSF67_RS10130	COG2200	EAL domain
GSF67_RS10130	COG2199	diguanylate cyclase activity
GSF67_RS10145	COG1278	Cold shock
GSF67_RS10150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSF67_RS10160	COG1846	Transcriptional regulator
GSF67_RS10165	COG0745	RESPONSE REGULATOR receiver
GSF67_RS10170	COG2205	protein histidine kinase activity
GSF67_RS10175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSF67_RS10200	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GSF67_RS10225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GSF67_RS10235	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GSF67_RS10250	COG0840	transmembrane signaling receptor activity
GSF67_RS10255	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_RS10265	COG5001	Diguanylate cyclase
GSF67_RS10265	COG3300	MHYT domain
GSF67_RS10270	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GSF67_RS10275	COG5001	Diguanylate cyclase
GSF67_RS10285	COG0193	aminoacyl-tRNA hydrolase activity
GSF67_RS10295	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GSF67_RS10315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GSF67_RS10320	COG2857	Cytochrome c1
GSF67_RS10320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GSF67_RS10335	COG3021	interspecies interaction between organisms
GSF67_RS10340	COG1132	(ABC) transporter
GSF67_RS10345	COG1132	(ABC) transporter
GSF67_RS10350	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GSF67_RS10355	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GSF67_RS10370	COG0408	coproporphyrinogen oxidase activity
GSF67_RS10385	COG0617	tRNA 3'-terminal CCA addition
GSF67_RS10400	COG0714	Associated with various cellular activities
GSF67_RS10420	COG0454	-acetyltransferase
GSF67_RS10425	COG0477	Major facilitator Superfamily
GSF67_RS10435	COG0435	Glutathione S-transferase
GSF67_RS10440	COG0494	nUDIX hydrolase
GSF67_RS10450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GSF67_RS10455	COG3135	benzoate transporter
GSF67_RS10470	COG1595	DNA-templated transcription, initiation
GSF67_RS10480	COG0740	serine-type endopeptidase activity
GSF67_RS10495	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GSF67_RS10500	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GSF67_RS10525	COG4175	Glycine betaine
GSF67_RS10540	COG1435	thymidine kinase activity
GSF67_RS10560	COG2862	Uncharacterized protein family, UPF0114
GSF67_RS10575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GSF67_RS10575	COG0512	Glutamine amidotransferase of anthranilate synthase
GSF67_RS10590	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GSF67_RS10605	COG0366	Alpha amylase catalytic
GSF67_RS10610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_RS10630	COG1160	GTP binding
GSF67_RS10650	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GSF67_RS10660	COG0024	Methionine aminopeptidase
GSF67_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS10680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GSF67_RS10690	COG0583	DNA-binding transcription factor activity
GSF67_RS10705	COG0402	S-adenosylhomocysteine deaminase activity
GSF67_RS10720	COG1304	FMN binding
GSF67_RS10730	COG1309	transcriptional regulator
GSF67_RS10735	COG1686	Belongs to the peptidase S11 family
GSF67_RS10745	COG2351	hydroxyisourate hydrolase activity
GSF67_RS10750	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GSF67_RS10765	COG3195	allantoin biosynthetic process
GSF67_RS10765	COG3648	Uricase
GSF67_RS10775	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GSF67_RS10785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS10785	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GSF67_RS10795	COG0513	Belongs to the DEAD box helicase family
GSF67_RS10800	COG0697	spore germination
GSF67_RS10805	COG2259	Doxx family
GSF67_RS10810	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_RS10820	COG2308	Evidence 4 Homologs of previously reported genes of
GSF67_RS10830	COG1305	Transglutaminase-like
GSF67_RS10835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GSF67_RS10845	COG0456	acetyltransferase
GSF67_RS10860	COG4214	carbohydrate transport
GSF67_RS10865	COG1129	ABC transporter
GSF67_RS10870	COG4213	ABC transporter substrate-binding protein
GSF67_RS10995	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GSF67_RS11005	COG0840	transmembrane signaling receptor activity
GSF67_RS11010	COG2814	Major facilitator Superfamily
GSF67_RS11015	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GSF67_RS11015	COG0646	methionine synthase
GSF67_RS11025	COG4215	(ABC) transporter
GSF67_RS11030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS11060	COG1215	transferase activity, transferring glycosyl groups
GSF67_RS11090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GSF67_RS11095	COG2346	COG2346, Truncated hemoglobins
GSF67_RS11120	COG1309	transcriptional regulator
GSF67_RS11135	COG0494	nUDIX hydrolase
GSF67_RS11145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_RS11150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_RS11175	COG1234	tRNA 3'-trailer cleavage
GSF67_RS11180	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GSF67_RS11185	COG0830	nickel cation binding
GSF67_RS11190	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GSF67_RS11205	COG0804	urea catabolic process
GSF67_RS11210	COG1442	glycosyl transferase family 8
GSF67_RS11215	COG3755	Protein conserved in bacteria
GSF67_RS11225	COG0832	Belongs to the urease beta subunit family
GSF67_RS11230	COG3813	Protein conserved in bacteria
GSF67_RS11235	COG0831	urea catabolic process
GSF67_RS11240	COG0829	nickel cation binding
GSF67_RS11255	COG0411	ABC transporter
GSF67_RS11265	COG0559	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS11280	COG0174	glutamine synthetase
GSF67_RS11285	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS11290	COG0784	Response regulator, receiver
GSF67_RS11290	COG5002	protein histidine kinase activity
GSF67_RS11290	COG2198	Histidine kinase
GSF67_RS11340	COG1218	3'(2'),5'-bisphosphate nucleotidase
GSF67_RS11415	COG0564	pseudouridine synthase activity
GSF67_RS11425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GSF67_RS11435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GSF67_RS11460	COG0346	lactoylglutathione lyase activity
GSF67_RS11470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GSF67_RS11480	COG2832	Protein of unknown function (DUF454)
GSF67_RS11485	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GSF67_RS11490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_RS11495	COG4558	Periplasmic binding protein
GSF67_RS11505	COG3721	Heme iron utilization protein
GSF67_RS11520	COG2205	protein histidine kinase activity
GSF67_RS11560	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_RS11565	COG4605	iron ion homeostasis
GSF67_RS11570	COG4604	ABC transporter, ATP-binding protein
GSF67_RS11575	COG0783	Belongs to the Dps family
GSF67_RS11590	COG0583	DNA-binding transcription factor activity
GSF67_RS11600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_RS11620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GSF67_RS11625	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GSF67_RS11630	COG0288	reversible hydration of carbon dioxide
GSF67_RS11640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GSF67_RS11655	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GSF67_RS11660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GSF67_RS11665	COG0778	Nitroreductase
GSF67_RS11670	COG2267	carboxylic ester hydrolase activity
GSF67_RS11675	COG0251	oxidation-reduction process
GSF67_RS11680	COG1335	isochorismatase
GSF67_RS11685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS11695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_RS11710	COG1175	transmembrane transport
GSF67_RS11715	COG0395	ABC-type sugar transport system, permease component
GSF67_RS11720	COG3842	ATPase activity
GSF67_RS11725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_RS11735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GSF67_RS11750	COG4608	Belongs to the ABC transporter superfamily
GSF67_RS11755	COG0444	Belongs to the ABC transporter superfamily
GSF67_RS11765	COG0601	transmembrane transport
GSF67_RS11785	COG0392	lysyltransferase activity
GSF67_RS11785	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GSF67_RS11825	COG2159	amidohydrolase
GSF67_RS11830	COG1960	acyl-CoA dehydrogenase activity
GSF67_RS11855	COG2205	protein histidine kinase activity
GSF67_RS11860	COG0745	RESPONSE REGULATOR receiver
GSF67_RS11870	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSF67_RS11870	COG1902	pentaerythritol trinitrate reductase activity
GSF67_RS11885	COG3842	ATPase activity
GSF67_RS11890	COG3842	ATPase activity
GSF67_RS11900	COG0395	ABC-type sugar transport system, permease component
GSF67_RS11905	COG1175	transmembrane transport
GSF67_RS11915	COG1609	Transcriptional regulator
GSF67_RS11955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GSF67_RS11965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_RS11970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GSF67_RS11980	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GSF67_RS11990	COG1509	lysine 2,3-aminomutase activity
GSF67_RS12005	COG0583	DNA-binding transcription factor activity
GSF67_RS12010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS12020	COG0725	ABC transporter, periplasmic molybdate-binding protein
GSF67_RS12025	COG4149	molybdate abc transporter
GSF67_RS12030	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GSF67_RS12040	COG3191	aminopeptidase activity
GSF67_RS12045	COG2022	thiamine diphosphate biosynthetic process
GSF67_RS12060	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GSF67_RS12065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GSF67_RS12075	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GSF67_RS12100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GSF67_RS12125	COG0438	transferase activity, transferring glycosyl groups
GSF67_RS12145	COG4166	transmembrane transport
GSF67_RS12150	COG0601	transmembrane transport
GSF67_RS12155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS12165	COG0438	transferase activity, transferring glycosyl groups
GSF67_RS12170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GSF67_RS12175	COG3142	Participates in the control of copper homeostasis
GSF67_RS12180	COG2814	Major facilitator Superfamily
GSF67_RS12195	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS12200	COG1737	Transcriptional regulator
GSF67_RS12210	COG3842	ATPase activity
GSF67_RS12220	COG0395	ABC-type sugar transport system, permease component
GSF67_RS12225	COG1175	transmembrane transport
GSF67_RS12235	COG2188	Transcriptional regulator
GSF67_RS12240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GSF67_RS12245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GSF67_RS12250	COG1940	carbohydrate kinase activity
GSF67_RS12260	COG0671	phosphoesterase, PA-phosphatase related
GSF67_RS12265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GSF67_RS12270	COG0156	8-amino-7-oxononanoate synthase activity
GSF67_RS12280	COG0729	surface antigen
GSF67_RS12290	COG0835	chemotaxis
GSF67_RS12300	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GSF67_RS12305	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GSF67_RS12310	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GSF67_RS12315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GSF67_RS12320	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GSF67_RS12325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GSF67_RS12340	COG4974	Belongs to the 'phage' integrase family
GSF67_RS12365	COG1280	lysine exporter protein (LysE YggA)
GSF67_RS12375	COG0508	dehydrogenase complex catalyzes the overall conversion of
GSF67_RS12385	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GSF67_RS12390	COG0045	succinate-CoA ligase (ADP-forming) activity
GSF67_RS12395	COG0039	L-malate dehydrogenase activity
GSF67_RS12400	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GSF67_RS12435	COG2264	protein methyltransferase activity
GSF67_RS12450	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GSF67_RS12455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GSF67_RS12460	COG0181	hydroxymethylbilane synthase activity
GSF67_RS12500	COG1872	DUF167
GSF67_RS12505	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GSF67_RS12520	COG0339	signal peptide processing
GSF67_RS12525	COG1846	Transcriptional regulator
GSF67_RS12530	COG2814	Major facilitator Superfamily
GSF67_RS12535	COG0137	argininosuccinate synthase activity
GSF67_RS12545	COG1280	lysine exporter protein (LysE YggA)
GSF67_RS12550	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GSF67_RS12555	COG4120	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS12565	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GSF67_RS12580	COG2154	pterin-4-alpha-carbinolamine dehydratase
GSF67_RS12585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GSF67_RS12590	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GSF67_RS12600	COG4181	ATPase activity
GSF67_RS12610	COG0670	Belongs to the BI1 family
GSF67_RS12625	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GSF67_RS12630	COG4133	protoheme IX ABC transporter activity
GSF67_RS12635	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GSF67_RS12640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GSF67_RS12655	COG3706	GGDEF domain
GSF67_RS12665	COG2917	probably involved in intracellular septation
GSF67_RS12670	COG0552	protein localization to endoplasmic reticulum
GSF67_RS12675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GSF67_RS12680	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GSF67_RS12690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GSF67_RS12695	COG1605	Chorismate mutase
GSF67_RS12695	COG0287	Prephenate dehydrogenase
GSF67_RS12700	COG0228	four-way junction DNA binding
GSF67_RS12705	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GSF67_RS12710	COG0336	Belongs to the RNA methyltransferase TrmD family
GSF67_RS12720	COG0335	large ribosomal subunit rRNA binding
GSF67_RS12725	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
GSF67_RS12730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_RS12745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GSF67_RS12755	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GSF67_RS12785	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GSF67_RS12795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GSF67_RS12800	COG0142	geranyltranstransferase activity
GSF67_RS12805	COG2885	chlorophyll binding
GSF67_RS12810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GSF67_RS12815	COG2223	nitrite transmembrane transporter activity
GSF67_RS12820	COG1349	DNA-binding transcription factor activity
GSF67_RS12825	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GSF67_RS12830	COG2197	response regulator
GSF67_RS12835	COG1132	(ABC) transporter
GSF67_RS12845	COG3459	Glycosyltransferase 36 associated
GSF67_RS12850	COG1473	amidohydrolase
GSF67_RS12855	COG0579	oxidoreductase
GSF67_RS12865	COG0129	dihydroxy-acid dehydratase activity
GSF67_RS12870	COG2084	Dehydrogenase
GSF67_RS12875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_RS12880	COG0277	FAD linked oxidase domain protein
GSF67_RS12885	COG2186	Transcriptional regulator
GSF67_RS12895	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GSF67_RS12900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_RS12905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GSF67_RS12910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GSF67_RS12920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GSF67_RS12925	COG0495	leucyl-tRNA aminoacylation
GSF67_RS12940	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GSF67_RS12955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GSF67_RS12960	COG1946	Acyl-CoA thioesterase
GSF67_RS12965	COG0347	Belongs to the P(II) protein family
GSF67_RS12970	COG0004	ammonium transporteR
GSF67_RS12975	COG1674	ftsk spoiiie
GSF67_RS12980	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GSF67_RS12995	COG0745	RESPONSE REGULATOR receiver
GSF67_RS13005	COG1329	Transcriptional regulator
GSF67_RS13010	COG2902	Dehydrogenase
GSF67_RS13015	COG2270	Major facilitator Superfamily
GSF67_RS13030	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS13045	COG0494	nUDIX hydrolase
GSF67_RS13055	COG0793	Belongs to the peptidase S41A family
GSF67_RS13065	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GSF67_RS13070	COG0799	negative regulation of ribosome biogenesis
GSF67_RS13075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GSF67_RS13080	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GSF67_RS13085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GSF67_RS13090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GSF67_RS13105	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GSF67_RS13110	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GSF67_RS13135	COG0066	3-isopropylmalate dehydratase activity
GSF67_RS13140	COG0473	3-isopropylmalate dehydrogenase activity
GSF67_RS13145	COG1858	cytochrome C peroxidase
GSF67_RS13150	COG1797	cobyrinic acid a,c-diamide synthase activity
GSF67_RS13155	COG1648	precorrin-2 dehydrogenase activity
GSF67_RS13155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GSF67_RS13160	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GSF67_RS13225	COG1492	cobalamin metabolic process
GSF67_RS13240	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_RS13245	COG3254	rhamnose metabolic process
GSF67_RS13250	COG0246	Mannitol dehydrogenase
GSF67_RS13255	COG1063	alcohol dehydrogenase
GSF67_RS13275	COG4214	carbohydrate transport
GSF67_RS13280	COG1129	ABC transporter
GSF67_RS13285	COG2186	Transcriptional regulator
GSF67_RS13290	COG2721	sulfolactate sulfo-lyase activity
GSF67_RS13295	COG0138	bifunctional purine biosynthesis protein purh
GSF67_RS13305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GSF67_RS13305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GSF67_RS13310	COG0501	Belongs to the peptidase M48B family
GSF67_RS13330	COG0357	Ribosomal RNA small subunit methyltransferase G
GSF67_RS13335	COG0445	tRNA wobble uridine modification
GSF67_RS13340	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GSF67_RS13345	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GSF67_RS13355	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GSF67_RS13360	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GSF67_RS13365	COG0424	maF-like protein
GSF67_RS13370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GSF67_RS13375	COG0237	dephospho-CoA kinase activity
GSF67_RS13385	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GSF67_RS13390	COG3030	protein affecting phage T7 exclusion by the F plasmid
GSF67_RS13400	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GSF67_RS13425	COG0179	Fumarylacetoacetate (FAA) hydrolase
GSF67_RS13440	COG0135	phosphoribosylanthranilate isomerase activity
GSF67_RS13445	COG0133	tryptophan synthase activity
GSF67_RS13450	COG0159	tryptophan synthase activity
GSF67_RS13455	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GSF67_RS13470	COG1074	ATP-dependent DNA helicase activity
GSF67_RS13480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GSF67_RS13490	COG2205	protein histidine kinase activity
GSF67_RS13495	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GSF67_RS13500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GSF67_RS13505	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GSF67_RS13505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GSF67_RS13510	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GSF67_RS13515	COG0642	Histidine kinase
GSF67_RS13520	COG0745	RESPONSE REGULATOR receiver
GSF67_RS13525	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GSF67_RS13535	COG1072	(Pantothenic acid kinase))
GSF67_RS13540	COG0140	phosphoribosyl-ATP diphosphatase activity
GSF67_RS13545	COG0107	imidazoleglycerol-phosphate synthase activity
GSF67_RS13550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GSF67_RS13555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GSF67_RS13565	COG0131	Imidazoleglycerol-phosphate dehydratase
GSF67_RS13570	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GSF67_RS13575	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GSF67_RS13585	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GSF67_RS13600	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GSF67_RS13610	COG1643	Atp-dependent helicase
GSF67_RS13645	COG0514	ATP-dependent DNA helicase (RecQ)
GSF67_RS13670	COG1072	(Pantothenic acid kinase))
GSF67_RS13680	COG1780	Probably involved in ribonucleotide reductase function
GSF67_RS13700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GSF67_RS13730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_RS13740	COG2813	Specifically methylates the guanine in position
GSF67_RS13745	COG1185	polyribonucleotide nucleotidyltransferase activity
GSF67_RS13750	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GSF67_RS13755	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GSF67_RS13760	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GSF67_RS13765	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GSF67_RS13765	COG3064	Membrane
GSF67_RS13780	COG0779	Required for maturation of 30S ribosomal subunits
GSF67_RS13785	COG2814	Major facilitator Superfamily
GSF67_RS13790	COG2951	lytic endotransglycosylase activity
GSF67_RS13795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GSF67_RS13805	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GSF67_RS13810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GSF67_RS13825	COG2816	NAD+ diphosphatase activity
GSF67_RS13830	COG0077	Prephenate dehydratase
GSF67_RS13830	COG1605	Chorismate mutase
GSF67_RS13835	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GSF67_RS13840	COG3474	cytochrome
GSF67_RS13850	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GSF67_RS13855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GSF67_RS13865	COG1278	Cold shock
GSF67_RS13870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GSF67_RS13885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GSF67_RS13885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GSF67_RS13895	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GSF67_RS13925	COG2900	Belongs to the SlyX family
GSF67_RS13935	COG0484	heat shock protein binding
GSF67_RS13940	COG0443	Heat shock 70 kDa protein
GSF67_RS13955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GSF67_RS13980	COG0295	cytidine deaminase activity
GSF67_RS13985	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GSF67_RS13990	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GSF67_RS13995	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GSF67_RS14005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GSF67_RS14010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GSF67_RS14015	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GSF67_RS14025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GSF67_RS14030	COG1845	cytochrome c oxidase, subunit III
GSF67_RS14035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GSF67_RS14045	COG0477	Major facilitator Superfamily
GSF67_RS14050	COG0067	glutamate synthase
GSF67_RS14050	COG0070	glutamate synthase
GSF67_RS14050	COG0069	glutamate synthase activity
GSF67_RS14055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GSF67_RS14070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GSF67_RS14080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GSF67_RS14110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_RS14130	COG0848	biopolymer transport protein
GSF67_RS14140	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GSF67_RS14155	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GSF67_RS14160	COG3454	Phosphonate metabolism
GSF67_RS14165	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GSF67_RS14170	COG3639	organic phosphonate transmembrane transporter activity
GSF67_RS14175	COG3639	organic phosphonate transmembrane transporter activity
GSF67_RS14180	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GSF67_RS14185	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GSF67_RS14195	COG4778	phosphonate C-P lyase system protein PhnL
GSF67_RS14200	COG4107	phosphonate C-P lyase system protein PhnK
GSF67_RS14205	COG3627	carbon phosphorus lyase activity
GSF67_RS14210	COG3626	phosphonate metabolism
GSF67_RS14215	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GSF67_RS14220	COG3624	Phosphonate C-P lyase system protein PhnG
GSF67_RS14225	COG2188	Transcriptional regulator
GSF67_RS14230	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GSF67_RS14235	COG0837	glucose binding
GSF67_RS14240	COG1803	Methylglyoxal synthase
GSF67_RS14245	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GSF67_RS14250	COG4166	transmembrane transport
GSF67_RS14255	COG4174	ABC transporter (Permease)
GSF67_RS14260	COG4239	(ABC) transporter, permease
GSF67_RS14275	COG4172	Belongs to the ABC transporter superfamily
GSF67_RS14280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS14285	COG0174	glutamine synthetase
GSF67_RS14290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS14295	COG3265	gluconokinase activity
GSF67_RS14300	COG1174	glycine betaine transport
GSF67_RS14305	COG1125	glycine betaine transport
GSF67_RS14310	COG1174	glycine betaine transport
GSF67_RS14315	COG1732	Glycine betaine
GSF67_RS14325	COG1959	2 iron, 2 sulfur cluster binding
GSF67_RS14330	COG1840	ABC-type Fe3 transport system, periplasmic component
GSF67_RS14350	COG0697	spore germination
GSF67_RS14365	COG0791	NLP P60 protein
GSF67_RS14375	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GSF67_RS14380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GSF67_RS14415	COG4964	Belongs to the GSP D family
GSF67_RS14460	COG3422	double-strand break repair
GSF67_RS14465	COG3757	hydrolase, family 25
GSF67_RS14470	COG0697	spore germination
GSF67_RS14475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSF67_RS14525	COG0481	GTPase activity
GSF67_RS14530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GSF67_RS14545	COG1396	sequence-specific DNA binding
GSF67_RS14560	COG1917	Cupin 2, conserved barrel domain protein
GSF67_RS14560	COG2169	Transcriptional regulator
GSF67_RS14565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GSF67_RS14590	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GSF67_RS14595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GSF67_RS14600	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GSF67_RS14610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GSF67_RS14615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSF67_RS14615	COG0072	phenylalanine-tRNA ligase activity
GSF67_RS14620	COG0667	Aldo Keto reductase
GSF67_RS14635	COG0667	Aldo Keto reductase
GSF67_RS14640	COG4977	sequence-specific DNA binding
GSF67_RS14665	COG1570	exodeoxyribonuclease VII activity
GSF67_RS14670	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_RS14680	COG1846	Transcriptional regulator
GSF67_RS14685	COG0697	spore germination
GSF67_RS14690	COG2309	aminopeptidase activity
GSF67_RS14695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GSF67_RS14700	COG1393	Belongs to the ArsC family
GSF67_RS14725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GSF67_RS14725	COG0519	Catalyzes the synthesis of GMP from XMP
GSF67_RS14740	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GSF67_RS14770	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GSF67_RS14780	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GSF67_RS14790	COG1968	undecaprenyl-diphosphatase activity
GSF67_RS14810	COG0284	orotidine-5'-phosphate decarboxylase activity
GSF67_RS14820	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GSF67_RS14830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GSF67_RS14835	COG0792	nuclease activity
GSF67_RS14850	COG1175	transmembrane transport
GSF67_RS14855	COG0395	ABC-type sugar transport system, permease component
GSF67_RS14860	COG3842	ATPase activity
GSF67_RS14870	COG0189	ligase activity
GSF67_RS14875	COG0606	chelatase, subunit chli
GSF67_RS14880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GSF67_RS14885	COG1280	lysine exporter protein (LysE YggA)
GSF67_RS14890	COG0756	dUTP diphosphatase activity
GSF67_RS14895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GSF67_RS14900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GSF67_RS14915	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GSF67_RS14920	COG2226	methyltransferase
GSF67_RS14925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GSF67_RS14930	COG1024	Enoyl-CoA hydratase
GSF67_RS14935	COG0268	Binds directly to 16S ribosomal RNA
GSF67_RS14975	COG0438	transferase activity, transferring glycosyl groups
GSF67_RS14995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GSF67_RS15025	COG4566	intracellular signal transduction
GSF67_RS15030	COG2197	response regulator
GSF67_RS15035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GSF67_RS15040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_RS15045	COG4310	Domain of unknown function (DUF2172)
GSF67_RS15050	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GSF67_RS15060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GSF67_RS15065	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GSF67_RS15070	COG2197	response regulator
GSF67_RS15095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_RS15110	COG0483	inositol monophosphate 1-phosphatase activity
GSF67_RS15115	COG3842	ATPase activity
GSF67_RS15125	COG1840	ABC-type Fe3 transport system, periplasmic component
GSF67_RS15130	COG1840	ABC-type Fe3 transport system, periplasmic component
GSF67_RS15135	COG0745	RESPONSE REGULATOR receiver
GSF67_RS15140	COG4191	Histidine kinase
GSF67_RS15140	COG0784	Response regulator, receiver
GSF67_RS15170	COG0596	Alpha beta hydrolase
GSF67_RS15175	COG0745	RESPONSE REGULATOR receiver
GSF67_RS15185	COG1764	response to oxidative stress
GSF67_RS15195	COG0596	Alpha beta hydrolase
GSF67_RS15215	COG0783	Belongs to the Dps family
GSF67_RS15220	COG0243	molybdopterin cofactor binding
GSF67_RS15230	COG4566	intracellular signal transduction
GSF67_RS15245	COG2140	Oxalate decarboxylase
GSF67_RS15275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSF67_RS15280	COG1522	sequence-specific DNA binding
GSF67_RS15285	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_RS15290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GSF67_RS15295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSF67_RS15300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GSF67_RS15305	COG2423	ornithine cyclodeaminase activity
GSF67_RS15310	COG0006	proline dipeptidase activity
GSF67_RS15315	COG3608	succinylglutamate desuccinylase aspartoacylase
GSF67_RS15320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS15325	COG0765	amino acid transport
GSF67_RS15330	COG0765	amino acid transport
GSF67_RS15335	COG1126	abc transporter atp-binding protein
GSF67_RS15345	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_RS15360	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS15365	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS15370	COG1129	ABC transporter
GSF67_RS15390	COG3284	Transcriptional regulator
GSF67_RS15395	COG1063	alcohol dehydrogenase
GSF67_RS15405	COG0110	maltose O-acetyltransferase activity
GSF67_RS15415	COG0840	transmembrane signaling receptor activity
GSF67_RS15420	COG1049	propionate catabolic process, 2-methylcitrate cycle
GSF67_RS15445	COG0488	(ABC) transporter
GSF67_RS15450	COG5265	(ABC) transporter
GSF67_RS15455	COG3181	Tripartite tricarboxylate transporter family receptor
GSF67_RS15460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GSF67_RS15470	COG3237	CsbD-like
GSF67_RS15480	COG0405	Gamma-glutamyltransferase
GSF67_RS15490	COG0601	transmembrane transport
GSF67_RS15495	COG0747	negative chemotaxis
GSF67_RS15500	COG2186	Transcriptional regulator
GSF67_RS15505	COG2197	response regulator
GSF67_RS15510	COG3237	CsbD-like
GSF67_RS15530	COG0745	RESPONSE REGULATOR receiver
GSF67_RS15535	COG2205	protein histidine kinase activity
GSF67_RS15535	COG2770	Histidine kinase
GSF67_RS15540	COG2223	nitrite transmembrane transporter activity
GSF67_RS15550	COG3383	formate dehydrogenase (NAD+) activity
GSF67_RS15575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GSF67_RS15580	COG1802	Transcriptional regulator
GSF67_RS15585	COG4608	Belongs to the ABC transporter superfamily
GSF67_RS15590	COG0444	Belongs to the ABC transporter superfamily
GSF67_RS15595	COG0402	S-adenosylhomocysteine deaminase activity
GSF67_RS15605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS15620	COG0402	S-adenosylhomocysteine deaminase activity
GSF67_RS15635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_RS15645	COG0765	amino acid transport
GSF67_RS15655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS15670	COG3938	Belongs to the proline racemase family
GSF67_RS15680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS15690	COG0765	amino acid transport
GSF67_RS15705	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GSF67_RS15710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_RS15720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GSF67_RS15725	COG0784	Response regulator, receiver
GSF67_RS15740	COG0842	Transport permease protein
GSF67_RS15745	COG1129	ABC transporter
GSF67_RS15745	COG0842	Transport permease protein
GSF67_RS15750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_RS15755	COG1486	melibiose metabolic process
GSF67_RS15760	COG4172	Belongs to the ABC transporter superfamily
GSF67_RS15765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS15770	COG0601	transmembrane transport
GSF67_RS15775	COG0747	negative chemotaxis
GSF67_RS15780	COG1486	melibiose metabolic process
GSF67_RS15805	COG1940	carbohydrate kinase activity
GSF67_RS15810	COG2182	Extracellular solute-binding protein
GSF67_RS15815	COG1175	transmembrane transport
GSF67_RS15820	COG0395	ABC-type sugar transport system, permease component
GSF67_RS15825	COG0165	Argininosuccinate lyase
GSF67_RS15830	COG3842	ATPase activity
GSF67_RS15835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_RS15840	COG3119	arylsulfatase activity
GSF67_RS15855	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_RS15870	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GSF67_RS15900	COG1392	Phosphate transport regulator
GSF67_RS15905	COG0306	phosphate transporter
GSF67_RS15910	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GSF67_RS15920	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GSF67_RS15930	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS15935	COG3300	MHYT domain
GSF67_RS15935	COG5001	Diguanylate cyclase
GSF67_RS15945	COG0747	negative chemotaxis
GSF67_RS15950	COG1312	Catalyzes the dehydration of D-mannonate
GSF67_RS15955	COG2186	Transcriptional regulator
GSF67_RS15960	COG0601	transmembrane transport
GSF67_RS15965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS15970	COG0444	Belongs to the ABC transporter superfamily
GSF67_RS15990	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GSF67_RS15995	COG1088	dTDP-glucose 4,6-dehydratase activity
GSF67_RS16000	COG1091	dTDP-4-dehydrorhamnose reductase activity
GSF67_RS16005	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GSF67_RS16015	COG1215	transferase activity, transferring glycosyl groups
GSF67_RS16025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GSF67_RS16055	COG1132	(ABC) transporter
GSF67_RS16065	COG0583	DNA-binding transcription factor activity
GSF67_RS16070	COG0667	Aldo Keto reductase
GSF67_RS16075	COG0385	Bile acid
GSF67_RS16105	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GSF67_RS16110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GSF67_RS16120	COG1177	transmembrane transport
GSF67_RS16125	COG3842	ATPase activity
GSF67_RS16145	COG0300	oxidoreductase activity
GSF67_RS16165	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GSF67_RS16175	COG3842	ATPase activity
GSF67_RS16180	COG1175	transmembrane transport
GSF67_RS16185	COG0395	ABC-type sugar transport system, permease component
GSF67_RS16190	COG1609	Transcriptional regulator
GSF67_RS16200	COG0673	inositol 2-dehydrogenase activity
GSF67_RS16205	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_RS16215	COG1609	Transcriptional regulator
GSF67_RS16220	COG0183	Belongs to the thiolase family
GSF67_RS16225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GSF67_RS16235	COG1414	Transcriptional regulator
GSF67_RS16250	COG0583	DNA-binding transcription factor activity
GSF67_RS16260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GSF67_RS16265	COG3485	protocatechuate 3,4-dioxygenase
GSF67_RS16270	COG3485	protocatechuate 3,4-dioxygenase
GSF67_RS16280	COG0765	amino acid transport
GSF67_RS16285	COG0765	amino acid transport
GSF67_RS16290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS16295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS16300	COG1126	abc transporter atp-binding protein
GSF67_RS16305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GSF67_RS16310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GSF67_RS16335	COG0747	negative chemotaxis
GSF67_RS16345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS16360	COG0683	leucine binding
GSF67_RS16380	COG1137	ATPase activity
GSF67_RS16395	COG3962	Belongs to the TPP enzyme family
GSF67_RS16405	COG3718	enzyme involved in inositol metabolism
GSF67_RS16410	COG0673	inositol 2-dehydrogenase activity
GSF67_RS16415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_RS16420	COG1609	Transcriptional regulator
GSF67_RS16425	COG1846	Transcriptional regulator
GSF67_RS16435	COG0523	cobalamin synthesis protein
GSF67_RS16470	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GSF67_RS16490	COG0800	Aldolase
GSF67_RS16495	COG2954	triphosphatase activity
GSF67_RS16510	COG5001	Diguanylate cyclase
GSF67_RS16510	COG3300	MHYT domain
GSF67_RS16520	COG2011	ABC-type metal ion transport system permease component
GSF67_RS16525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GSF67_RS16530	COG0778	Nitroreductase
GSF67_RS16545	COG2115	Belongs to the xylose isomerase family
GSF67_RS16550	COG1070	Carbohydrate kinase
GSF67_RS16555	COG1609	Transcriptional regulator
GSF67_RS16570	COG1309	transcriptional regulator
GSF67_RS16575	COG1253	flavin adenine dinucleotide binding
GSF67_RS16580	COG0471	metal ion transport
GSF67_RS16580	COG3273	potassium ion transport
GSF67_RS16585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GSF67_RS16590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GSF67_RS16600	COG0803	Belongs to the bacterial solute-binding protein 9 family
GSF67_RS16605	COG1121	(ABC) transporter
GSF67_RS16610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GSF67_RS16615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GSF67_RS16625	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS16630	COG1414	Transcriptional regulator
GSF67_RS16635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GSF67_RS16645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GSF67_RS16665	COG1737	Transcriptional regulator
GSF67_RS16670	COG1069	ribulokinase activity
GSF67_RS16675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF67_RS16690	COG0395	ABC-type sugar transport system, permease component
GSF67_RS16695	COG1175	transmembrane transport
GSF67_RS16705	COG2390	Transcriptional regulator
GSF67_RS16710	COG4172	Belongs to the ABC transporter superfamily
GSF67_RS16715	COG1473	amidohydrolase
GSF67_RS16725	COG0601	transmembrane transport
GSF67_RS16740	COG0693	protein deglycase activity
GSF67_RS16745	COG0154	amidase activity
GSF67_RS16750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS16760	COG0747	negative chemotaxis
GSF67_RS16765	COG0583	DNA-binding transcription factor activity
GSF67_RS16770	COG4608	Belongs to the ABC transporter superfamily
GSF67_RS16775	COG0444	Belongs to the ABC transporter superfamily
GSF67_RS16785	COG0601	transmembrane transport
GSF67_RS16790	COG0747	negative chemotaxis
GSF67_RS16805	COG1473	amidohydrolase
GSF67_RS16815	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GSF67_RS16825	COG3842	ATPase activity
GSF67_RS16835	COG1176	ABC-type spermidine putrescine transport system, permease component I
GSF67_RS16845	COG1609	Transcriptional regulator
GSF67_RS16850	COG0583	DNA-binding transcription factor activity
GSF67_RS16855	COG1960	acyl-CoA dehydrogenase activity
GSF67_RS16870	COG3189	MarR family transcriptional regulator
GSF67_RS16895	COG0673	inositol 2-dehydrogenase activity
GSF67_RS16905	COG1609	Transcriptional regulator
GSF67_RS16910	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS16915	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS16920	COG1129	ABC transporter
GSF67_RS16925	COG1879	ABC-type sugar transport system periplasmic component
GSF67_RS16940	COG1609	Transcriptional regulator
GSF67_RS16945	COG0673	inositol 2-dehydrogenase activity
GSF67_RS16955	COG1653	transport
GSF67_RS16960	COG1175	transmembrane transport
GSF67_RS16965	COG0395	ABC-type sugar transport system, permease component
GSF67_RS16970	COG3842	ATPase activity
GSF67_RS16985	COG1253	flavin adenine dinucleotide binding
GSF67_RS16995	COG5001	Diguanylate cyclase
GSF67_RS17020	COG3501	Rhs element vgr protein
GSF67_RS17145	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS17155	COG1879	ABC-type sugar transport system periplasmic component
GSF67_RS17165	COG1063	alcohol dehydrogenase
GSF67_RS17170	COG1309	transcriptional regulator
GSF67_RS17185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GSF67_RS17195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GSF67_RS17195	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSF67_RS17205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS17210	COG0047	phosphoribosylformylglycinamidine synthase activity
GSF67_RS17230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GSF67_RS17235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GSF67_RS17250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSF67_RS17255	COG5002	protein histidine kinase activity
GSF67_RS17255	COG2205	protein histidine kinase activity
GSF67_RS17255	COG0784	Response regulator, receiver
GSF67_RS17260	COG4191	Histidine kinase
GSF67_RS17265	COG0668	transmembrane transport
GSF67_RS17285	COG4566	intracellular signal transduction
GSF67_RS17295	COG0668	transmembrane transport
GSF67_RS17300	COG2207	Transcriptional regulator
GSF67_RS17310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GSF67_RS17325	COG2814	Major facilitator Superfamily
GSF67_RS17330	COG0583	DNA-binding transcription factor activity
GSF67_RS17335	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GSF67_RS17340	COG0583	DNA-binding transcription factor activity
GSF67_RS17355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GSF67_RS17360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS17365	COG1126	abc transporter atp-binding protein
GSF67_RS17370	COG0765	amino acid transport
GSF67_RS17375	COG0765	amino acid transport
GSF67_RS17380	COG4221	oxidoreductase activity
GSF67_RS17390	COG0436	Aminotransferase
GSF67_RS17395	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GSF67_RS17400	COG1984	allophanate hydrolase subunit 2
GSF67_RS17415	COG0439	Biotin carboxylase
GSF67_RS17420	COG0511	ligase activity, forming carbon-carbon bonds
GSF67_RS17430	COG0583	DNA-binding transcription factor activity
GSF67_RS17445	COG1280	lysine exporter protein (LysE YggA)
GSF67_RS17455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSF67_RS17465	COG0583	DNA-binding transcription factor activity
GSF67_RS17470	COG2828	Protein conserved in bacteria
GSF67_RS17485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_RS17495	COG0601	transmembrane transport
GSF67_RS17500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS17505	COG4172	Belongs to the ABC transporter superfamily
GSF67_RS17515	COG3842	ATPase activity
GSF67_RS17520	COG1177	transmembrane transport
GSF67_RS17540	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_RS17545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS17555	COG2267	carboxylic ester hydrolase activity
GSF67_RS17565	COG1454	alcohol dehydrogenase
GSF67_RS17570	COG1126	abc transporter atp-binding protein
GSF67_RS17595	COG0174	glutamine synthetase
GSF67_RS17600	COG0069	glutamate synthase activity
GSF67_RS17605	COG2218	PFAM glutamate synthase alpha subunit domain protein
GSF67_RS17610	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GSF67_RS17620	COG4977	sequence-specific DNA binding
GSF67_RS17625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS17630	COG4311	Sarcosine oxidase, delta subunit
GSF67_RS17635	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSF67_RS17635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GSF67_RS17645	COG0300	oxidoreductase activity
GSF67_RS17675	COG1278	Cold shock
GSF67_RS17705	COG1881	PFAM PEBP family protein
GSF67_RS17735	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_RS17740	COG4172	Belongs to the ABC transporter superfamily
GSF67_RS17745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS17750	COG0601	transmembrane transport
GSF67_RS17755	COG0747	negative chemotaxis
GSF67_RS17770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_RS17805	COG0739	heme binding
GSF67_RS17805	COG0741	lytic transglycosylase activity
GSF67_RS17805	COG1196	nuclear chromosome segregation
GSF67_RS17810	COG0542	response to heat
GSF67_RS17820	COG2890	protein-(glutamine-N5) methyltransferase activity
GSF67_RS17825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GSF67_RS17835	COG0527	aspartate kinase activity
GSF67_RS17840	COG0513	Belongs to the DEAD box helicase family
GSF67_RS17850	COG0019	diaminopimelate decarboxylase activity
GSF67_RS17865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GSF67_RS17875	COG3920	Histidine kinase
GSF67_RS17885	COG0784	Response regulator, receiver
GSF67_RS17900	COG1522	sequence-specific DNA binding
GSF67_RS17910	COG1116	anion transmembrane transporter activity
GSF67_RS17915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_RS17920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSF67_RS17925	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_RS17930	COG0583	DNA-binding transcription factor activity
GSF67_RS17940	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GSF67_RS17945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_RS17950	COG0189	ligase activity
GSF67_RS17970	COG0693	protein deglycase activity
GSF67_RS18000	COG3685	Protein conserved in bacteria
GSF67_RS18005	COG4993	Dehydrogenase
GSF67_RS18025	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS18030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GSF67_RS18050	COG0559	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS18075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS18090	COG4608	Belongs to the ABC transporter superfamily
GSF67_RS18095	COG0444	Belongs to the ABC transporter superfamily
GSF67_RS18100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS18105	COG0601	transmembrane transport
GSF67_RS18110	COG0747	negative chemotaxis
GSF67_RS18115	COG0006	proline dipeptidase activity
GSF67_RS18120	COG4221	oxidoreductase activity
GSF67_RS18150	COG0539	negative regulation of cytoplasmic translation
GSF67_RS18155	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GSF67_RS18185	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GSF67_RS18190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GSF67_RS18220	COG1294	oxidase, subunit
GSF67_RS18230	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GSF67_RS18235	COG4988	ABC transporter
GSF67_RS18245	COG1063	alcohol dehydrogenase
GSF67_RS18250	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS18255	COG2084	Dehydrogenase
GSF67_RS18265	COG1522	sequence-specific DNA binding
GSF67_RS18270	COG1794	racemase activity, acting on amino acids and derivatives
GSF67_RS18280	COG0058	SHG alpha-glucan phosphorylase activity
GSF67_RS18285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GSF67_RS18290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GSF67_RS18295	COG0297	glycogen (starch) synthase activity
GSF67_RS18300	COG0033	Phosphoglucomutase
GSF67_RS18305	COG1523	belongs to the glycosyl hydrolase 13 family
GSF67_RS18330	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSF67_RS18330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GSF67_RS18345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS18350	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GSF67_RS18370	COG1215	transferase activity, transferring glycosyl groups
GSF67_RS18375	COG2327	Polysaccharide pyruvyl transferase
GSF67_RS18380	COG0463	Glycosyl transferase, family 2
GSF67_RS18385	COG2244	polysaccharide biosynthetic process
GSF67_RS18390	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GSF67_RS18395	COG2273	Hydrolase Family 16
GSF67_RS18400	COG0438	transferase activity, transferring glycosyl groups
GSF67_RS18410	COG1215	transferase activity, transferring glycosyl groups
GSF67_RS18415	COG1215	transferase activity, transferring glycosyl groups
GSF67_RS18420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GSF67_RS18425	COG3206	protein involved in exopolysaccharide biosynthesis
GSF67_RS18425	COG0489	protein tyrosine kinase activity
GSF67_RS18430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSF67_RS18435	COG4191	Histidine kinase
GSF67_RS18435	COG0784	Response regulator, receiver
GSF67_RS18445	COG4176	ABC-type proline glycine betaine transport system permease component
GSF67_RS18450	COG4175	Glycine betaine
GSF67_RS18450	COG0517	IMP dehydrogenase activity
GSF67_RS18465	COG0564	pseudouridine synthase activity
GSF67_RS18470	COG0500	methyltransferase
GSF67_RS18480	COG2133	pyrroloquinoline quinone binding
GSF67_RS18490	COG2197	response regulator
GSF67_RS18495	COG4585	Histidine kinase
GSF67_RS18500	COG1879	ABC-type sugar transport system periplasmic component
GSF67_RS18505	COG1129	ABC transporter
GSF67_RS18510	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS18520	COG3386	PFAM SMP-30 Gluconolaconase
GSF67_RS18525	COG2137	regulation of response to DNA damage stimulus
GSF67_RS18530	COG3474	cytochrome
GSF67_RS18540	COG1120	ATPase activity
GSF67_RS18555	COG4774	siderophore transport
GSF67_RS18560	COG0583	DNA-binding transcription factor activity
GSF67_RS18570	COG2194	sulfuric ester hydrolase activity
GSF67_RS18575	COG0745	RESPONSE REGULATOR receiver
GSF67_RS18580	COG0642	Histidine kinase
GSF67_RS18585	COG0477	Major facilitator Superfamily
GSF67_RS18605	COG0673	inositol 2-dehydrogenase activity
GSF67_RS18610	COG0697	spore germination
GSF67_RS18620	COG0010	Belongs to the arginase family
GSF67_RS18650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GSF67_RS18655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GSF67_RS18660	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GSF67_RS18670	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GSF67_RS18720	COG0477	Major facilitator Superfamily
GSF67_RS18725	COG0583	DNA-binding transcription factor activity
GSF67_RS18740	COG2814	Major facilitator Superfamily
GSF67_RS18755	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GSF67_RS18770	COG0346	lactoylglutathione lyase activity
GSF67_RS18775	COG0583	DNA-binding transcription factor activity
GSF67_RS18800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GSF67_RS18805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_RS18815	COG3842	ATPase activity
GSF67_RS18820	COG0395	ABC-type sugar transport system, permease component
GSF67_RS18825	COG1175	transmembrane transport
GSF67_RS18835	COG0673	inositol 2-dehydrogenase activity
GSF67_RS18840	COG0673	inositol 2-dehydrogenase activity
GSF67_RS18865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_RS18870	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_RS18875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS18885	COG4175	Glycine betaine
GSF67_RS18885	COG3448	diguanylate cyclase activity
GSF67_RS18895	COG4176	ABC-type proline glycine betaine transport system permease component
GSF67_RS18900	COG3938	Belongs to the proline racemase family
GSF67_RS18905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS18930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS18975	COG0402	S-adenosylhomocysteine deaminase activity
GSF67_RS18980	COG1228	amidohydrolase
GSF67_RS18985	COG2986	histidine ammonia-lyase
GSF67_RS18995	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GSF67_RS19030	COG1192	Involved in chromosome partitioning
GSF67_RS19035	COG1475	DNA binding
GSF67_RS19040	COG1414	Transcriptional regulator
GSF67_RS19055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GSF67_RS19060	COG4771	TonB-dependent receptor
GSF67_RS19070	COG0366	Alpha amylase catalytic
GSF67_RS19075	COG4770	biotin carboxylase activity
GSF67_RS19080	COG1984	allophanate hydrolase subunit 2
GSF67_RS19085	COG4336	lyase activity
GSF67_RS19090	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GSF67_RS19095	COG1914	H( )-stimulated, divalent metal cation uptake system
GSF67_RS19100	COG1802	Transcriptional regulator
GSF67_RS19105	COG3707	response regulator
GSF67_RS19115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSF67_RS19120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_RS19125	COG1116	anion transmembrane transporter activity
GSF67_RS19130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GSF67_RS19140	COG0243	molybdopterin cofactor binding
GSF67_RS19145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GSF67_RS19145	COG1648	precorrin-2 dehydrogenase activity
GSF67_RS19160	COG3842	ATPase activity
GSF67_RS19175	COG0395	ABC-type sugar transport system, permease component
GSF67_RS19190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GSF67_RS19205	COG0071	Belongs to the small heat shock protein (HSP20) family
GSF67_RS19240	COG1129	ABC transporter
GSF67_RS19245	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS19255	COG0667	Aldo Keto reductase
GSF67_RS19260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GSF67_RS19265	COG1830	Aldolase
GSF67_RS19275	COG1846	Transcriptional regulator
GSF67_RS19285	COG1304	FMN binding
GSF67_RS19290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_RS19295	COG0488	(ABC) transporter
GSF67_RS19310	COG2308	Evidence 4 Homologs of previously reported genes of
GSF67_RS19310	COG2307	Protein conserved in bacteria
GSF67_RS19360	COG4372	Transposase
GSF67_RS19370	COG2963	transposase activity
GSF67_RS19375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSF67_RS19405	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GSF67_RS19430	COG0583	DNA-binding transcription factor activity
GSF67_RS19465	COG1879	ABC-type sugar transport system periplasmic component
GSF67_RS19470	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS19480	COG1129	ABC transporter
GSF67_RS19485	COG2721	sulfolactate sulfo-lyase activity
GSF67_RS19500	COG3254	rhamnose metabolic process
GSF67_RS19505	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS19515	COG1335	isochorismatase
GSF67_RS19525	COG0667	Aldo Keto reductase
GSF67_RS19530	COG0583	DNA-binding transcription factor activity
GSF67_RS19535	COG1522	sequence-specific DNA binding
GSF67_RS19550	COG2814	Major facilitator Superfamily
GSF67_RS19555	COG2986	histidine ammonia-lyase
GSF67_RS19560	COG4175	Glycine betaine
GSF67_RS19560	COG0517	IMP dehydrogenase activity
GSF67_RS19565	COG4176	ABC-type proline glycine betaine transport system permease component
GSF67_RS19605	COG2186	Transcriptional regulator
GSF67_RS19610	COG1027	Aspartate ammonia-lyase
GSF67_RS19620	COG0252	asparaginase activity
GSF67_RS19630	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GSF67_RS19640	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GSF67_RS19645	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GSF67_RS19650	COG2205	protein histidine kinase activity
GSF67_RS19655	COG0745	RESPONSE REGULATOR receiver
GSF67_RS19665	COG0067	glutamate synthase
GSF67_RS19665	COG0069	glutamate synthase activity
GSF67_RS19665	COG0070	glutamate synthase
GSF67_RS19680	COG2205	protein histidine kinase activity
GSF67_RS19695	COG2951	lytic endotransglycosylase activity
GSF67_RS19700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GSF67_RS19725	COG0330	HflC and HflK could
GSF67_RS19730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GSF67_RS19735	COG0737	Belongs to the 5'-nucleotidase family
GSF67_RS19745	COG5310	Homospermidine synthase
GSF67_RS19755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GSF67_RS19760	COG1164	Oligoendopeptidase f
GSF67_RS19765	COG2204	response regulator
GSF67_RS19770	COG3108	Peptidase M15
GSF67_RS19775	COG0469	pyruvate kinase activity
GSF67_RS19795	COG3750	Belongs to the UPF0335 family
GSF67_RS19800	COG0457	Tetratricopeptide repeat
GSF67_RS19805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GSF67_RS19810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GSF67_RS19815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GSF67_RS19845	COG0483	inositol monophosphate 1-phosphatase activity
GSF67_RS19865	COG1132	(ABC) transporter
GSF67_RS19870	COG0254	rRNA binding
GSF67_RS19895	COG3588	fructose-bisphosphate aldolase
GSF67_RS19900	COG0126	phosphoglycerate kinase activity
GSF67_RS19935	COG1253	flavin adenine dinucleotide binding
GSF67_RS19945	COG1692	metallophosphoesterase
GSF67_RS19960	COG0217	transcriptional regulatory protein
GSF67_RS19965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS19970	COG0840	transmembrane signaling receptor activity
GSF67_RS19975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GSF67_RS19980	COG0632	four-way junction helicase activity
GSF67_RS19985	COG2255	four-way junction helicase activity
GSF67_RS19995	COG2318	DinB family
GSF67_RS20000	COG0494	nUDIX hydrolase
GSF67_RS20010	COG0824	Thioesterase
GSF67_RS20030	COG0823	Involved in the tonB-independent uptake of proteins
GSF67_RS20035	COG2885	chlorophyll binding
GSF67_RS20045	COG0037	tRNA processing
GSF67_RS20050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GSF67_RS20055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GSF67_RS20070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSF67_RS20085	COG0482	sulfurtransferase activity
GSF67_RS20095	COG0625	glutathione transferase activity
GSF67_RS20110	COG3118	belongs to the thioredoxin family
GSF67_RS20120	COG2835	tetraacyldisaccharide 4'-kinase activity
GSF67_RS20125	COG2373	Large extracellular alpha-helical protein
GSF67_RS20130	COG4953	penicillin-binding protein 1C
GSF67_RS20145	COG1120	ATPase activity
GSF67_RS20150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_RS20155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_RS20160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GSF67_RS20165	COG4774	siderophore transport
GSF67_RS20165	COG1629	transport
GSF67_RS20185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GSF67_RS20220	COG2226	methyltransferase
GSF67_RS20250	COG0534	Mate efflux family protein
GSF67_RS20260	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GSF67_RS20265	COG1959	2 iron, 2 sulfur cluster binding
GSF67_RS20270	COG1473	amidohydrolase
GSF67_RS20275	COG1686	Belongs to the peptidase S11 family
GSF67_RS20280	COG0523	cobalamin synthesis protein
GSF67_RS20285	COG0425	Belongs to the sulfur carrier protein TusA family
GSF67_RS20285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GSF67_RS20290	COG3034	peptidoglycan biosynthetic process
GSF67_RS20295	COG0825	malonyl-CoA metabolic process
GSF67_RS20300	COG4974	Belongs to the 'phage' integrase family
GSF67_RS20310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GSF67_RS20315	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GSF67_RS20345	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GSF67_RS20350	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GSF67_RS20365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSF67_RS20370	COG2226	methyltransferase
GSF67_RS20375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GSF67_RS20380	COG0287	Prephenate dehydrogenase
GSF67_RS20390	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GSF67_RS20410	COG2884	Cell division ATP-binding protein ftsE
GSF67_RS20450	COG0165	Argininosuccinate lyase
GSF67_RS20455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GSF67_RS20465	COG1250	3-hydroxyacyl-CoA dehydrogenase
GSF67_RS20475	COG2086	electron transfer activity
GSF67_RS20485	COG2096	Adenosyltransferase
GSF67_RS20495	COG0300	oxidoreductase activity
GSF67_RS20505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GSF67_RS20515	COG3800	Transcriptional regulator
GSF67_RS20515	COG1396	sequence-specific DNA binding
GSF67_RS20520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GSF67_RS20525	COG0625	glutathione transferase activity
GSF67_RS20535	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GSF67_RS20545	COG4770	biotin carboxylase activity
GSF67_RS20550	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GSF67_RS20550	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GSF67_RS20555	COG0346	lactoylglutathione lyase activity
GSF67_RS20570	COG4213	ABC transporter substrate-binding protein
GSF67_RS20575	COG4214	carbohydrate transport
GSF67_RS20580	COG1129	ABC transporter
GSF67_RS20590	COG1396	sequence-specific DNA binding
GSF67_RS20635	COG2273	Hydrolase Family 16
GSF67_RS20635	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GSF67_RS20640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GSF67_RS20655	COG0438	transferase activity, transferring glycosyl groups
GSF67_RS20660	COG0297	glycogen (starch) synthase activity
GSF67_RS20680	COG0489	protein tyrosine kinase activity
GSF67_RS20680	COG3206	protein involved in exopolysaccharide biosynthesis
GSF67_RS20690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GSF67_RS20705	COG2244	polysaccharide biosynthetic process
GSF67_RS20715	COG0438	transferase activity, transferring glycosyl groups
GSF67_RS20735	COG3273	potassium ion transport
GSF67_RS20735	COG0471	metal ion transport
GSF67_RS20740	COG2376	Dihydroxyacetone kinase
GSF67_RS20770	COG1129	ABC transporter
GSF67_RS20780	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS20800	COG0246	Mannitol dehydrogenase
GSF67_RS20805	COG1312	Catalyzes the dehydration of D-mannonate
GSF67_RS20845	COG0697	spore germination
GSF67_RS20850	COG0653	protein targeting
GSF67_RS20855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GSF67_RS20860	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GSF67_RS20870	COG0494	nUDIX hydrolase
GSF67_RS20885	COG2226	methyltransferase
GSF67_RS20890	COG1040	competence protein
GSF67_RS20900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GSF67_RS20910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GSF67_RS20930	COG4150	thiosulfate binding
GSF67_RS20940	COG4208	sulfate ABC transporter
GSF67_RS20945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GSF67_RS20950	COG4335	DNA alkylation repair
GSF67_RS20965	COG5001	Diguanylate cyclase
GSF67_RS20970	COG2264	protein methyltransferase activity
GSF67_RS20985	COG3254	rhamnose metabolic process
GSF67_RS20995	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS21000	COG1129	ABC transporter
GSF67_RS21010	COG1349	DNA-binding transcription factor activity
GSF67_RS21015	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS21015	COG3347	Dehydrogenase
GSF67_RS21020	COG4952	isomerase
GSF67_RS21025	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GSF67_RS21030	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GSF67_RS21035	COG1024	Enoyl-CoA hydratase
GSF67_RS21050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GSF67_RS21055	COG1960	acyl-CoA dehydrogenase activity
GSF67_RS21070	COG1960	acyl-CoA dehydrogenase activity
GSF67_RS21080	COG0022	dehydrogenase e1 component
GSF67_RS21090	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GSF67_RS21095	COG2391	methyltransferase activity
GSF67_RS21105	COG0640	Transcriptional regulator
GSF67_RS21110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSF67_RS21110	COG3453	Protein conserved in bacteria
GSF67_RS21120	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS21135	COG2186	Transcriptional regulator
GSF67_RS21145	COG0601	transmembrane transport
GSF67_RS21155	COG0444	Belongs to the ABC transporter superfamily
GSF67_RS21160	COG4608	Belongs to the ABC transporter superfamily
GSF67_RS21180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS21185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS21200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS21220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS21225	COG0583	DNA-binding transcription factor activity
GSF67_RS21235	COG0667	Aldo Keto reductase
GSF67_RS21270	COG1960	acyl-CoA dehydrogenase activity
GSF67_RS21275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS21290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS21295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GSF67_RS21305	COG1959	2 iron, 2 sulfur cluster binding
GSF67_RS21310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS21315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS21320	COG1473	amidohydrolase
GSF67_RS21330	COG1126	abc transporter atp-binding protein
GSF67_RS21345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS21350	COG1522	sequence-specific DNA binding
GSF67_RS21355	COG4172	Belongs to the ABC transporter superfamily
GSF67_RS21360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS21365	COG0601	transmembrane transport
GSF67_RS21395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS21400	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_RS21405	COG0473	3-isopropylmalate dehydrogenase activity
GSF67_RS21410	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_RS21420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSF67_RS21440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_RS21445	COG1120	ATPase activity
GSF67_RS21455	COG2226	methyltransferase
GSF67_RS21470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_RS21475	COG1120	ATPase activity
GSF67_RS21480	COG1595	DNA-templated transcription, initiation
GSF67_RS21500	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
GSF67_RS21505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_RS21510	COG0583	DNA-binding transcription factor activity
GSF67_RS21515	COG0601	transmembrane transport
GSF67_RS21540	COG1473	amidohydrolase
GSF67_RS21550	COG1129	ABC transporter
GSF67_RS21555	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS21560	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GSF67_RS21565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GSF67_RS21570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_RS21575	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GSF67_RS21590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS21600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS21605	COG2079	MmgE PrpD family protein
GSF67_RS21610	COG1126	abc transporter atp-binding protein
GSF67_RS21615	COG0765	amino acid transport
GSF67_RS21630	COG0281	malic enzyme
GSF67_RS21630	COG0280	phosphate acetyltransferase
GSF67_RS21635	COG0583	DNA-binding transcription factor activity
GSF67_RS21655	COG1175	transmembrane transport
GSF67_RS21660	COG0395	ABC-type sugar transport system, permease component
GSF67_RS21675	COG0673	inositol 2-dehydrogenase activity
GSF67_RS21680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GSF67_RS21685	COG0720	synthase
GSF67_RS21690	COG0602	queuosine metabolic process
GSF67_RS21695	COG0673	inositol 2-dehydrogenase activity
GSF67_RS21705	COG3842	ATPase activity
GSF67_RS21720	COG1653	transport
GSF67_RS21725	COG1609	Transcriptional regulator
GSF67_RS21740	COG2094	Belongs to the DNA glycosylase MPG family
GSF67_RS21750	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS21760	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_RS21760	COG1388	LysM domain
GSF67_RS21765	COG2972	Histidine kinase
GSF67_RS21765	COG0840	transmembrane signaling receptor activity
GSF67_RS21780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GSF67_RS21785	COG1596	polysaccharide export
GSF67_RS21790	COG3307	-O-antigen
GSF67_RS21820	COG2197	response regulator
GSF67_RS21855	COG2942	2-epimerase
GSF67_RS21865	COG1215	transferase activity, transferring glycosyl groups
GSF67_RS21885	COG1473	amidohydrolase
GSF67_RS21900	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS21905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GSF67_RS21915	COG1301	dicarboxylic acid transport
GSF67_RS21920	COG4191	Histidine kinase
GSF67_RS21925	COG2204	response regulator
GSF67_RS21940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS21945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GSF67_RS21950	COG1522	sequence-specific DNA binding
GSF67_RS21955	COG0351	phosphomethylpyrimidine kinase
GSF67_RS21960	COG0352	thiamine-phosphate diphosphorylase activity
GSF67_RS21965	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GSF67_RS21970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSF67_RS21975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_RS21980	COG1501	Belongs to the glycosyl hydrolase 31 family
GSF67_RS21985	COG0395	ABC-type sugar transport system, permease component
GSF67_RS21990	COG1175	transmembrane transport
GSF67_RS21995	COG1653	transport
GSF67_RS22000	COG3842	ATPase activity
GSF67_RS22015	COG4989	oxidoreductase activity
GSF67_RS22060	COG0601	transmembrane transport
GSF67_RS22070	COG3964	amidohydrolase
GSF67_RS22085	COG1921	L-seryl-tRNASec selenium transferase activity
GSF67_RS22090	COG4172	Belongs to the ABC transporter superfamily
GSF67_RS22095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_RS22100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GSF67_RS22115	COG1312	Catalyzes the dehydration of D-mannonate
GSF67_RS22120	COG1063	alcohol dehydrogenase
GSF67_RS22125	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_RS22135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GSF67_RS22140	COG2186	Transcriptional regulator
GSF67_RS22145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF67_RS22150	COG0850	regulation of cytokinetic process
GSF67_RS22155	COG2894	cell division
GSF67_RS22160	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GSF67_RS22170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS22175	COG5001	Diguanylate cyclase
GSF67_RS22190	COG0673	inositol 2-dehydrogenase activity
GSF67_RS22200	COG1653	transport
GSF67_RS22205	COG1175	transmembrane transport
GSF67_RS22210	COG0395	ABC-type sugar transport system, permease component
GSF67_RS22215	COG3842	ATPase activity
GSF67_RS22225	COG0673	inositol 2-dehydrogenase activity
GSF67_RS22255	COG0587	DNA-directed DNA polymerase activity
GSF67_RS22270	COG2186	Transcriptional regulator
GSF67_RS22275	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS22280	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS22285	COG1129	ABC transporter
GSF67_RS22290	COG1879	ABC-type sugar transport system periplasmic component
GSF67_RS22295	COG0129	dihydroxy-acid dehydratase activity
GSF67_RS22310	COG4608	Belongs to the ABC transporter superfamily
GSF67_RS22320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS22325	COG0601	transmembrane transport
GSF67_RS22330	COG0747	negative chemotaxis
GSF67_RS22340	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GSF67_RS22345	COG5001	Diguanylate cyclase
GSF67_RS22355	COG3257	ureidoglycine aminohydrolase activity
GSF67_RS22360	COG5002	protein histidine kinase activity
GSF67_RS22360	COG3447	MASE1 domain protein
GSF67_RS22360	COG5001	Diguanylate cyclase
GSF67_RS22365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_RS22370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GSF67_RS22380	COG1129	ABC transporter
GSF67_RS22385	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS22390	COG1879	ABC-type sugar transport system periplasmic component
GSF67_RS22395	COG0583	DNA-binding transcription factor activity
GSF67_RS22420	COG3047	cAMP biosynthetic process
GSF67_RS22435	COG3842	ATPase activity
GSF67_RS22440	COG0395	ABC-type sugar transport system, permease component
GSF67_RS22445	COG1175	transmembrane transport
GSF67_RS22450	COG1653	transport
GSF67_RS22455	COG0523	cobalamin synthesis protein
GSF67_RS22470	COG0523	cobalamin synthesis protein
GSF67_RS22475	COG1121	(ABC) transporter
GSF67_RS22485	COG0803	Belongs to the bacterial solute-binding protein 9 family
GSF67_RS22490	COG0328	RNA-DNA hybrid ribonuclease activity
GSF67_RS22500	COG0626	cystathionine gamma-synthase activity
GSF67_RS22505	COG2182	Extracellular solute-binding protein
GSF67_RS22510	COG1175	transmembrane transport
GSF67_RS22515	COG0395	ABC-type sugar transport system, permease component
GSF67_RS22530	COG0395	ABC-type sugar transport system, permease component
GSF67_RS22535	COG1175	transmembrane transport
GSF67_RS22540	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
GSF67_RS22545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_RS22555	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS22560	COG1063	alcohol dehydrogenase
GSF67_RS22565	COG1609	Transcriptional regulator
GSF67_RS22580	COG2084	Dehydrogenase
GSF67_RS22585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GSF67_RS22595	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_RS22600	COG0583	DNA-binding transcription factor activity
GSF67_RS22605	COG2223	nitrite transmembrane transporter activity
GSF67_RS22655	COG2186	Transcriptional regulator
GSF67_RS22660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_RS22665	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GSF67_RS22670	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS22675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_RS22680	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_RS22685	COG3618	amidohydrolase
GSF67_RS22690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GSF67_RS22710	COG1175	transmembrane transport
GSF67_RS22715	COG0395	ABC-type sugar transport system, permease component
GSF67_RS22720	COG3842	ATPase activity
GSF67_RS22735	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GSF67_RS22760	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GSF67_RS22770	COG1278	Cold shock
GSF67_RS22780	COG0673	inositol 2-dehydrogenase activity
GSF67_RS22795	COG0673	inositol 2-dehydrogenase activity
GSF67_RS22800	COG1309	transcriptional regulator
GSF67_RS22805	COG1653	transport
GSF67_RS22810	COG1175	transmembrane transport
GSF67_RS22815	COG0395	ABC-type sugar transport system, permease component
GSF67_RS22820	COG3842	ATPase activity
GSF67_RS22825	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_RS22830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_RS22840	COG1609	Transcriptional regulator
GSF67_RS22870	COG1175	transmembrane transport
GSF67_RS22875	COG0395	ABC-type sugar transport system, permease component
GSF67_RS22880	COG3842	ATPase activity
GSF67_RS22885	COG0395	ABC-type sugar transport system, permease component
GSF67_RS22895	COG1653	transport
GSF67_RS22930	COG3842	ATPase activity
GSF67_RS22940	COG1176	ABC-type spermidine putrescine transport system, permease component I
GSF67_RS22945	COG0395	ABC-type sugar transport system, permease component
GSF67_RS22955	COG1595	DNA-templated transcription, initiation
GSF67_RS22995	COG2233	PERMEase
GSF67_RS23000	COG1309	transcriptional regulator
GSF67_RS23005	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS23010	COG1794	racemase activity, acting on amino acids and derivatives
GSF67_RS23045	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GSF67_RS23050	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS23065	COG1609	Transcriptional regulator
GSF67_RS23070	COG3706	GGDEF domain
GSF67_RS23075	COG4178	(ABC) transporter
GSF67_RS23080	COG0025	NhaP-type Na H and K H
GSF67_RS23090	COG1215	transferase activity, transferring glycosyl groups
GSF67_RS23135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_RS23140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_RS23150	COG1446	asparaginase
GSF67_RS23165	COG0747	negative chemotaxis
GSF67_RS23190	COG0601	transmembrane transport
GSF67_RS23195	COG2197	response regulator
GSF67_RS23220	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_RS23230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_RS23240	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS23250	COG1653	transport
GSF67_RS23255	COG0395	ABC-type sugar transport system, permease component
GSF67_RS23260	COG4209	transmembrane transport
GSF67_RS23265	COG3842	ATPase activity
GSF67_RS23310	COG0640	Transcriptional regulator
GSF67_RS23345	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GSF67_RS23355	COG3547	Transposase (IS116 IS110 IS902 family)
GSF67_RS23400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GSF67_RS23470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_RS23475	COG1126	abc transporter atp-binding protein
GSF67_RS23490	COG0640	Transcriptional regulator
GSF67_RS23495	COG1475	DNA binding
GSF67_RS23500	COG1192	Involved in chromosome partitioning
GSF67_RS23525	COG2207	Transcriptional regulator
GSF67_RS23545	COG1566	PFAM secretion protein HlyD family protein
GSF67_RS23555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GSF67_RS23605	COG3920	Histidine kinase
GSF67_RS23630	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS23665	COG1278	Cold shock
GSF67_RS23680	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GSF67_RS23685	COG0784	Response regulator, receiver
GSF67_RS23685	COG4191	Histidine kinase
GSF67_RS23725	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GSF67_RS23730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GSF67_RS23735	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GSF67_RS23740	COG2080	2 iron, 2 sulfur cluster binding
GSF67_RS23745	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GSF67_RS23750	COG1309	transcriptional regulator
GSF67_RS23760	COG3685	Protein conserved in bacteria
GSF67_RS23775	COG0753	catalase activity
GSF67_RS23825	COG0765	amino acid transport
GSF67_RS23835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GSF67_RS23840	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_RS23845	COG0006	proline dipeptidase activity
GSF67_RS23850	COG0504	CTP synthase activity
GSF67_RS23860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSF67_RS23870	COG2801	Transposase and inactivated derivatives
GSF67_RS23875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GSF67_RS23930	COG3831	ATPase activity
GSF67_RS23935	COG0776	regulation of translation
GSF67_RS23940	COG5489	Protein of unknown function (DUF736)
GSF67_RS23950	COG0300	oxidoreductase activity
GSF67_RS24010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_RS24035	COG1335	isochorismatase
GSF67_RS24040	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GSF67_RS24060	COG0346	lactoylglutathione lyase activity
GSF67_RS24065	COG0583	DNA-binding transcription factor activity
GSF67_RS24070	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GSF67_RS24080	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GSF67_RS24090	COG2814	Major facilitator Superfamily
GSF67_RS24095	COG0583	DNA-binding transcription factor activity
GSF67_RS24100	COG2010	Cytochrome c
GSF67_RS24100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GSF67_RS24105	COG2080	2 iron, 2 sulfur cluster binding
GSF67_RS24110	COG2010	Cytochrome c
GSF67_RS24110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GSF67_RS24115	COG1902	pentaerythritol trinitrate reductase activity
GSF67_RS24125	COG0783	Belongs to the Dps family
GSF67_RS24135	COG4566	intracellular signal transduction
GSF67_RS24140	COG4566	intracellular signal transduction
GSF67_RS24160	COG1902	pentaerythritol trinitrate reductase activity
GSF67_RS24175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_RS24180	COG1116	anion transmembrane transporter activity
GSF67_RS24185	COG1309	transcriptional regulator
GSF67_RS24190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GSF67_RS24230	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_RS24285	COG1335	isochorismatase
GSF67_RS24295	COG0583	DNA-binding transcription factor activity
GSF67_RS24335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF67_RS24360	COG1175	transmembrane transport
GSF67_RS24365	COG0395	ABC-type sugar transport system, permease component
GSF67_RS24370	COG3842	ATPase activity
GSF67_RS24390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GSF67_RS24410	COG0300	oxidoreductase activity
GSF67_RS24430	COG1475	DNA binding
GSF67_RS24490	COG0587	DNA-directed DNA polymerase activity
GSF67_RS24520	COG3547	Transposase (IS116 IS110 IS902 family)
GSF67_RS24550	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GSF67_RS24560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GSF67_RS24565	COG3119	arylsulfatase activity
GSF67_RS24580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GSF67_RS24595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_RS24605	COG3547	Transposase (IS116 IS110 IS902 family)
GSF67_RS24645	COG1959	2 iron, 2 sulfur cluster binding
GSF67_RS24665	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS24720	COG3547	Transposase (IS116 IS110 IS902 family)
GSF67_RS24735	COG4372	Transposase
GSF67_RS24745	COG2963	transposase activity
GSF67_RS24760	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GSF67_RS24785	COG2132	Multicopper oxidase
GSF67_RS24805	COG2205	protein histidine kinase activity
GSF67_RS24860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSF67_RS24870	COG3903	Transcriptional regulator
GSF67_RS24870	COG3629	intracellular signal transduction
GSF67_RS24905	COG0798	PFAM Bile acid sodium symporter
GSF67_RS24920	COG0640	Transcriptional regulator
GSF67_RS24955	COG0640	Transcriptional regulator
GSF67_RS24960	COG1475	DNA binding
GSF67_RS24965	COG1192	Involved in chromosome partitioning
GSF67_RS24975	COG4962	Type ii secretion system protein e
GSF67_RS24990	COG3451	type IV secretory pathway VirB4
GSF67_RS24995	COG5314	conjugation
GSF67_RS25005	COG3846	protein secretion by the type IV secretion system
GSF67_RS25010	COG3701	Conjugal transfer protein
GSF67_RS25035	COG1609	Transcriptional regulator
GSF67_RS25040	COG3250	beta-galactosidase activity
GSF67_RS25045	COG2814	Major facilitator Superfamily
GSF67_RS25050	COG4770	biotin carboxylase activity
GSF67_RS25055	COG0395	ABC-type sugar transport system, permease component
GSF67_RS25060	COG1175	transmembrane transport
GSF67_RS25075	COG0346	lactoylglutathione lyase activity
GSF67_RS25080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSF67_RS25085	COG0277	FAD linked oxidase domain protein
GSF67_RS25100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GSF67_RS25135	COG2086	electron transfer activity
GSF67_RS25150	COG0840	transmembrane signaling receptor activity
GSF67_RS25185	COG3842	ATPase activity
GSF67_RS25190	COG1177	transmembrane transport
GSF67_RS25195	COG0596	Alpha beta hydrolase
GSF67_RS25200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GSF67_RS25205	COG0022	dehydrogenase e1 component
GSF67_RS25210	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS25245	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_RS25255	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS25260	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GSF67_RS25265	COG0022	dehydrogenase e1 component
GSF67_RS25275	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS25295	COG4336	lyase activity
GSF67_RS25310	COG1129	ABC transporter
GSF67_RS25315	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_RS25320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GSF67_RS25325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GSF67_RS25330	COG4770	biotin carboxylase activity
GSF67_RS25335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GSF67_RS25380	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GSF67_RS25385	COG2181	nitrate reductase activity
GSF67_RS25385	COG0247	lactate metabolic process
GSF67_RS25390	COG0583	DNA-binding transcription factor activity
GSF67_RS25415	COG2186	Transcriptional regulator
GSF67_RS25420	COG1414	Transcriptional regulator
GSF67_RS25430	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GSF67_RS25455	COG2801	Transposase and inactivated derivatives
GSF67_RS25460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GSF67_RS25475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GSF67_RS25485	COG3158	transport of potassium into the cell
GSF67_RS25490	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS25495	COG1414	Transcriptional regulator
GSF67_RS25500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GSF67_RS25505	COG3842	ATPase activity
GSF67_RS25510	COG0395	ABC-type sugar transport system, permease component
GSF67_RS25515	COG1175	transmembrane transport
GSF67_RS25525	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_RS25530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_RS25535	COG3734	2-keto-3-deoxy-galactonokinase
GSF67_RS25565	COG0071	Belongs to the small heat shock protein (HSP20) family
GSF67_RS25570	COG3831	ATPase activity
GSF67_RS25580	COG0596	Alpha beta hydrolase
GSF67_RS25585	COG1902	pentaerythritol trinitrate reductase activity
GSF67_RS25590	COG4221	oxidoreductase activity
GSF67_RS25605	COG2972	Histidine kinase
GSF67_RS25605	COG0840	transmembrane signaling receptor activity
GSF67_RS25625	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS25635	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_RS25640	COG0673	inositol 2-dehydrogenase activity
GSF67_RS25645	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_RS25650	COG1609	Transcriptional regulator
GSF67_RS25670	COG0534	Mate efflux family protein
GSF67_RS25690	COG2072	flavoprotein involved in K transport
GSF67_RS25695	COG3842	ATPase activity
GSF67_RS25700	COG1177	transmembrane transport
GSF67_RS25715	COG0583	DNA-binding transcription factor activity
GSF67_RS25780	COG0297	glycogen (starch) synthase activity
GSF67_RS25785	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GSF67_RS25815	COG3685	Protein conserved in bacteria
GSF67_RS25825	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_RS25850	COG2378	regulation of single-species biofilm formation
GSF67_RS25860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_RS25865	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GSF67_RS25890	COG0395	ABC-type sugar transport system, permease component
GSF67_RS25895	COG3547	Transposase (IS116 IS110 IS902 family)
GSF67_RS25900	COG3177	Filamentation induced by cAMP protein fic
GSF67_RS25910	COG2020	methyltransferase activity
GSF67_RS25915	COG4644	lycopene metabolic process
GSF67_RS25935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSF67_RS25940	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins