locus-tag	class	description
J5276_RS00020	COG0501	Belongs to the peptidase M48B family
J5276_RS00025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J5276_RS00025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5276_RS00035	COG0138	bifunctional purine biosynthesis protein purh
J5276_RS00040	COG2721	sulfolactate sulfo-lyase activity
J5276_RS00045	COG2186	Transcriptional regulator
J5276_RS00050	COG1129	ABC transporter
J5276_RS00055	COG4214	carbohydrate transport
J5276_RS00075	COG1063	alcohol dehydrogenase
J5276_RS00080	COG0246	Mannitol dehydrogenase
J5276_RS00085	COG3254	rhamnose metabolic process
J5276_RS00090	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_RS00105	COG1492	cobalamin metabolic process
J5276_RS00170	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
J5276_RS00175	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5276_RS00175	COG1648	precorrin-2 dehydrogenase activity
J5276_RS00180	COG1797	cobyrinic acid a,c-diamide synthase activity
J5276_RS00185	COG1858	cytochrome C peroxidase
J5276_RS00190	COG0473	3-isopropylmalate dehydrogenase activity
J5276_RS00195	COG0066	3-isopropylmalate dehydratase activity
J5276_RS00220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5276_RS00225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J5276_RS00240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5276_RS00245	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5276_RS00250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J5276_RS00255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5276_RS00265	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5276_RS00275	COG0793	Belongs to the peptidase S41A family
J5276_RS00285	COG0494	nUDIX hydrolase
J5276_RS00300	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS00315	COG2270	Major facilitator Superfamily
J5276_RS00320	COG2902	Dehydrogenase
J5276_RS00325	COG1329	Transcriptional regulator
J5276_RS00335	COG0745	RESPONSE REGULATOR receiver
J5276_RS00350	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J5276_RS00355	COG1674	ftsk spoiiie
J5276_RS00360	COG0004	ammonium transporteR
J5276_RS00365	COG0347	Belongs to the P(II) protein family
J5276_RS00370	COG1946	Acyl-CoA thioesterase
J5276_RS00375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5276_RS00385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5276_RS00390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5276_RS00405	COG0495	leucyl-tRNA aminoacylation
J5276_RS00420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J5276_RS00425	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_RS00430	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5276_RS00435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5276_RS00445	COG2186	Transcriptional regulator
J5276_RS00450	COG0277	FAD linked oxidase domain protein
J5276_RS00455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_RS00460	COG2084	Dehydrogenase
J5276_RS00465	COG0129	dihydroxy-acid dehydratase activity
J5276_RS00475	COG0579	oxidoreductase
J5276_RS00480	COG1473	amidohydrolase
J5276_RS00485	COG3459	Glycosyltransferase 36 associated
J5276_RS00490	COG1132	(ABC) transporter
J5276_RS00495	COG2197	response regulator
J5276_RS00500	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J5276_RS00505	COG1349	DNA-binding transcription factor activity
J5276_RS00510	COG2223	nitrite transmembrane transporter activity
J5276_RS00515	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J5276_RS00520	COG2885	chlorophyll binding
J5276_RS00525	COG0142	geranyltranstransferase activity
J5276_RS00530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5276_RS00540	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J5276_RS00550	COG0488	(ABC) transporter
J5276_RS00570	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J5276_RS00580	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5276_RS00595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_RS00600	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
J5276_RS00605	COG0335	large ribosomal subunit rRNA binding
J5276_RS00615	COG0336	Belongs to the RNA methyltransferase TrmD family
J5276_RS00620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J5276_RS00625	COG0228	four-way junction DNA binding
J5276_RS00630	COG0287	Prephenate dehydrogenase
J5276_RS00630	COG1605	Chorismate mutase
J5276_RS00635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J5276_RS00645	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5276_RS00650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5276_RS00655	COG0552	protein localization to endoplasmic reticulum
J5276_RS00660	COG2917	probably involved in intracellular septation
J5276_RS00685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5276_RS00690	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5276_RS00695	COG4133	protoheme IX ABC transporter activity
J5276_RS00700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5276_RS00715	COG0670	Belongs to the BI1 family
J5276_RS00725	COG4181	ATPase activity
J5276_RS00735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J5276_RS00740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5276_RS00745	COG2154	pterin-4-alpha-carbinolamine dehydratase
J5276_RS00760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5276_RS00770	COG4120	Belongs to the binding-protein-dependent transport system permease family
J5276_RS00775	COG1122	ATPase activity
J5276_RS00780	COG1280	lysine exporter protein (LysE YggA)
J5276_RS00790	COG0137	argininosuccinate synthase activity
J5276_RS00800	COG1846	Transcriptional regulator
J5276_RS00810	COG0339	signal peptide processing
J5276_RS00815	COG1217	gtp-binding protein TYPA
J5276_RS00825	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J5276_RS00830	COG1872	DUF167
J5276_RS00870	COG0181	hydroxymethylbilane synthase activity
J5276_RS00875	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5276_RS00880	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5276_RS00895	COG2264	protein methyltransferase activity
J5276_RS00930	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J5276_RS00935	COG0039	L-malate dehydrogenase activity
J5276_RS00940	COG0045	succinate-CoA ligase (ADP-forming) activity
J5276_RS00945	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J5276_RS00950	COG0567	Dehydrogenase, E1 component
J5276_RS00955	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5276_RS00965	COG1280	lysine exporter protein (LysE YggA)
J5276_RS00990	COG4974	Belongs to the 'phage' integrase family
J5276_RS01005	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J5276_RS01010	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5276_RS01015	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5276_RS01020	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J5276_RS01025	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5276_RS01030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J5276_RS01040	COG0835	chemotaxis
J5276_RS01050	COG0729	surface antigen
J5276_RS01060	COG0156	8-amino-7-oxononanoate synthase activity
J5276_RS01065	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5276_RS01070	COG0671	phosphoesterase, PA-phosphatase related
J5276_RS01080	COG1940	carbohydrate kinase activity
J5276_RS01085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J5276_RS01090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J5276_RS01095	COG2188	Transcriptional regulator
J5276_RS01110	COG0395	ABC-type sugar transport system, permease component
J5276_RS01120	COG3842	ATPase activity
J5276_RS01130	COG1737	Transcriptional regulator
J5276_RS01135	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS01150	COG2814	Major facilitator Superfamily
J5276_RS01155	COG3142	Participates in the control of copper homeostasis
J5276_RS01160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5276_RS01165	COG0438	transferase activity, transferring glycosyl groups
J5276_RS01175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS01180	COG0601	transmembrane transport
J5276_RS01185	COG4166	transmembrane transport
J5276_RS01205	COG0438	transferase activity, transferring glycosyl groups
J5276_RS01230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5276_RS01235	COG1132	(ABC) transporter
J5276_RS01255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5276_RS01265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5276_RS01270	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J5276_RS01285	COG2022	thiamine diphosphate biosynthetic process
J5276_RS01300	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J5276_RS01305	COG4149	molybdate abc transporter
J5276_RS01310	COG0725	ABC transporter, periplasmic molybdate-binding protein
J5276_RS01315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS01320	COG0583	DNA-binding transcription factor activity
J5276_RS01340	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J5276_RS01345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5276_RS01355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5276_RS01360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_RS01370	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5276_RS01405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J5276_RS01405	COG1017	nitric oxide dioxygenase activity
J5276_RS01415	COG0277	FAD linked oxidase domain protein
J5276_RS01475	COG0643	Histidine kinase
J5276_RS01475	COG2198	Histidine kinase
J5276_RS01480	COG0835	chemotaxis
J5276_RS01485	COG0840	transmembrane signaling receptor activity
J5276_RS01490	COG0835	chemotaxis
J5276_RS01495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J5276_RS01500	COG2201	protein-glutamate methylesterase activity
J5276_RS01505	COG1192	Involved in chromosome partitioning
J5276_RS01525	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_RS01530	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_RS01540	COG3842	ATPase activity
J5276_RS01545	COG1902	pentaerythritol trinitrate reductase activity
J5276_RS01545	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5276_RS01555	COG0745	RESPONSE REGULATOR receiver
J5276_RS01585	COG1960	acyl-CoA dehydrogenase activity
J5276_RS01590	COG2159	amidohydrolase
J5276_RS01630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J5276_RS01630	COG0392	lysyltransferase activity
J5276_RS01650	COG0601	transmembrane transport
J5276_RS01655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS01660	COG0444	Belongs to the ABC transporter superfamily
J5276_RS01665	COG4608	Belongs to the ABC transporter superfamily
J5276_RS01680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J5276_RS01690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_RS01695	COG3842	ATPase activity
J5276_RS01700	COG0395	ABC-type sugar transport system, permease component
J5276_RS01705	COG1175	transmembrane transport
J5276_RS01720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_RS01730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS01735	COG1335	isochorismatase
J5276_RS01740	COG0251	oxidation-reduction process
J5276_RS01745	COG2267	carboxylic ester hydrolase activity
J5276_RS01750	COG0778	Nitroreductase
J5276_RS01755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5276_RS01760	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J5276_RS01775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5276_RS01785	COG0288	reversible hydration of carbon dioxide
J5276_RS01790	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J5276_RS01795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5276_RS01815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_RS01820	COG0657	acetylesterase activity
J5276_RS01825	COG0583	DNA-binding transcription factor activity
J5276_RS01835	COG2814	Major facilitator Superfamily
J5276_RS01840	COG0656	L-ascorbic acid biosynthetic process
J5276_RS01845	COG0840	transmembrane signaling receptor activity
J5276_RS01845	COG2972	Histidine kinase
J5276_RS01860	COG0783	Belongs to the Dps family
J5276_RS01865	COG4604	ABC transporter, ATP-binding protein
J5276_RS01870	COG4605	iron ion homeostasis
J5276_RS01875	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS01915	COG2205	protein histidine kinase activity
J5276_RS01935	COG3721	Heme iron utilization protein
J5276_RS01945	COG4558	Periplasmic binding protein
J5276_RS01950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS01955	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J5276_RS01960	COG2832	Protein of unknown function (DUF454)
J5276_RS01970	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J5276_RS01980	COG0346	lactoylglutathione lyase activity
J5276_RS02005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5276_RS02015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5276_RS02030	COG0564	pseudouridine synthase activity
J5276_RS02105	COG1218	3'(2'),5'-bisphosphate nucleotidase
J5276_RS02150	COG0784	Response regulator, receiver
J5276_RS02150	COG2198	Histidine kinase
J5276_RS02150	COG5002	protein histidine kinase activity
J5276_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS02160	COG0174	glutamine synthetase
J5276_RS02175	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5276_RS02185	COG0411	ABC transporter
J5276_RS02200	COG0829	nickel cation binding
J5276_RS02205	COG0831	urea catabolic process
J5276_RS02210	COG3813	Protein conserved in bacteria
J5276_RS02215	COG0832	Belongs to the urease beta subunit family
J5276_RS02225	COG3755	Protein conserved in bacteria
J5276_RS02230	COG1442	glycosyl transferase family 8
J5276_RS02235	COG0804	urea catabolic process
J5276_RS02250	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
J5276_RS02255	COG0830	nickel cation binding
J5276_RS02260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J5276_RS02290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_RS02295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_RS02305	COG0494	nUDIX hydrolase
J5276_RS02320	COG1309	transcriptional regulator
J5276_RS02340	COG2346	COG2346, Truncated hemoglobins
J5276_RS02345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5276_RS02360	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J5276_RS02375	COG1215	transferase activity, transferring glycosyl groups
J5276_RS02405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS02425	COG0840	transmembrane signaling receptor activity
J5276_RS02460	COG4213	ABC transporter substrate-binding protein
J5276_RS02465	COG1129	ABC transporter
J5276_RS02470	COG4214	carbohydrate transport
J5276_RS02500	COG1305	Transglutaminase-like
J5276_RS02510	COG2308	Evidence 4 Homologs of previously reported genes of
J5276_RS02520	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_RS02525	COG2259	Doxx family
J5276_RS02535	COG0513	Belongs to the DEAD box helicase family
J5276_RS02540	COG0784	Response regulator, receiver
J5276_RS02540	COG2205	protein histidine kinase activity
J5276_RS02540	COG5002	protein histidine kinase activity
J5276_RS02545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS02545	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J5276_RS02555	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
J5276_RS02580	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
J5276_RS02585	COG2351	hydroxyisourate hydrolase activity
J5276_RS02595	COG1686	Belongs to the peptidase S11 family
J5276_RS02600	COG1309	transcriptional regulator
J5276_RS02625	COG0402	S-adenosylhomocysteine deaminase activity
J5276_RS02640	COG0583	DNA-binding transcription factor activity
J5276_RS02650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J5276_RS02660	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS02670	COG0024	Methionine aminopeptidase
J5276_RS02680	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
J5276_RS02700	COG1160	GTP binding
J5276_RS02715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_RS02720	COG0366	Alpha amylase catalytic
J5276_RS02730	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J5276_RS02740	COG0512	Glutamine amidotransferase of anthranilate synthase
J5276_RS02740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5276_RS02755	COG2862	Uncharacterized protein family, UPF0114
J5276_RS02775	COG1435	thymidine kinase activity
J5276_RS02790	COG4175	Glycine betaine
J5276_RS02815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J5276_RS02820	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5276_RS02835	COG0740	serine-type endopeptidase activity
J5276_RS02850	COG4944	Protein of unknown function (DUF1109)
J5276_RS02855	COG3135	benzoate transporter
J5276_RS02860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5276_RS02875	COG0435	Glutathione S-transferase
J5276_RS02885	COG0477	Major facilitator Superfamily
J5276_RS02890	COG0454	-acetyltransferase
J5276_RS02910	COG0714	Associated with various cellular activities
J5276_RS02925	COG0617	tRNA 3'-terminal CCA addition
J5276_RS02940	COG0408	coproporphyrinogen oxidase activity
J5276_RS02955	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J5276_RS02965	COG1132	(ABC) transporter
J5276_RS02970	COG1132	(ABC) transporter
J5276_RS02990	COG2857	Cytochrome c1
J5276_RS02990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J5276_RS03000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J5276_RS03005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J5276_RS03025	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J5276_RS03035	COG0193	aminoacyl-tRNA hydrolase activity
J5276_RS03045	COG5001	Diguanylate cyclase
J5276_RS03050	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5276_RS03055	COG5001	Diguanylate cyclase
J5276_RS03055	COG3300	MHYT domain
J5276_RS03065	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS03070	COG0840	transmembrane signaling receptor activity
J5276_RS03085	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J5276_RS03095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5276_RS03110	COG1496	oxidoreductase activity
J5276_RS03120	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J5276_RS03140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5276_RS03145	COG2205	protein histidine kinase activity
J5276_RS03150	COG0745	RESPONSE REGULATOR receiver
J5276_RS03155	COG1846	Transcriptional regulator
J5276_RS03165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5276_RS03170	COG1278	Cold shock
J5276_RS03185	COG2199	diguanylate cyclase activity
J5276_RS03185	COG2200	EAL domain
J5276_RS03190	COG0436	Aminotransferase
J5276_RS03195	COG0387	Pfam Sodium calcium exchanger
J5276_RS03220	COG1902	pentaerythritol trinitrate reductase activity
J5276_RS03230	COG0583	DNA-binding transcription factor activity
J5276_RS03235	COG0492	ferredoxin-NADP+ reductase activity
J5276_RS03240	COG1522	sequence-specific DNA binding
J5276_RS03250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5276_RS03260	COG1573	uracil-dna glycosylase
J5276_RS03265	COG3706	GGDEF domain
J5276_RS03270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5276_RS03285	COG2321	neutral zinc metallopeptidase
J5276_RS03300	COG0534	Mate efflux family protein
J5276_RS03305	COG0505	Belongs to the CarA family
J5276_RS03315	COG0358	DNA primase activity
J5276_RS03320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5276_RS03335	COG0432	Pfam Uncharacterised protein family UPF0047
J5276_RS03345	COG2968	Membrane
J5276_RS03405	COG3842	ATPase activity
J5276_RS03425	COG1737	Transcriptional regulator
J5276_RS03435	COG0531	amino acid
J5276_RS03440	COG0174	glutamine synthetase
J5276_RS03445	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS03470	COG2814	Major facilitator Superfamily
J5276_RS03475	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_RS03490	COG0251	oxidation-reduction process
J5276_RS03505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5276_RS03510	COG2267	carboxylic ester hydrolase activity
J5276_RS03520	COG2226	methyltransferase
J5276_RS03540	COG4106	trans-aconitate 2-methyltransferase activity
J5276_RS03570	COG3023	N-Acetylmuramoyl-L-alanine amidase
J5276_RS03595	COG2001	Belongs to the MraZ family
J5276_RS03600	COG0275	rRNA processing
J5276_RS03615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5276_RS03625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5276_RS03630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5276_RS03640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5276_RS03645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5276_RS03650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J5276_RS03660	COG0477	Major facilitator Superfamily
J5276_RS03665	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5276_RS03670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J5276_RS03675	COG0849	cell division
J5276_RS03680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J5276_RS03690	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5276_RS03695	COG0497	DNA recombination
J5276_RS03700	COG1280	lysine exporter protein (LysE YggA)
J5276_RS03705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5276_RS03715	COG1247	-acetyltransferase
J5276_RS03725	COG0583	DNA-binding transcription factor activity
J5276_RS03730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J5276_RS03740	COG0835	chemotaxis
J5276_RS03750	COG1999	signal sequence binding
J5276_RS03755	COG2264	protein methyltransferase activity
J5276_RS03765	COG0006	proline dipeptidase activity
J5276_RS03785	COG1335	isochorismatase
J5276_RS03840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5276_RS03845	COG0277	FAD linked oxidase domain protein
J5276_RS03885	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J5276_RS03895	COG0330	HflC and HflK could
J5276_RS03900	COG0330	HflC and HflK could
J5276_RS03920	COG3830	Belongs to the UPF0237 family
J5276_RS03920	COG0560	Phosphoserine phosphatase
J5276_RS03925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5276_RS03935	COG0028	Belongs to the TPP enzyme family
J5276_RS03940	COG0440	acetolactate synthase activity
J5276_RS03955	COG0656	L-ascorbic acid biosynthetic process
J5276_RS03995	COG1090	epimerase
J5276_RS04000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J5276_RS04005	COG2197	response regulator
J5276_RS04010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5276_RS04015	COG1252	NADH dehydrogenase
J5276_RS04020	COG1064	alcohol dehydrogenase
J5276_RS04025	COG2207	Transcriptional regulator
J5276_RS04035	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5276_RS04050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5276_RS04055	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_RS04065	COG3842	ATPase activity
J5276_RS04075	COG3706	GGDEF domain
J5276_RS04090	COG0484	heat shock protein binding
J5276_RS04110	COG2382	esterase
J5276_RS04115	COG0556	nucleotide-excision repair
J5276_RS04125	COG1733	regulation of RNA biosynthetic process
J5276_RS04130	COG2910	NAD(P)H-binding
J5276_RS04155	COG1607	acyl-coa hydrolase
J5276_RS04160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5276_RS04190	COG0861	Integral membrane protein TerC family
J5276_RS04195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5276_RS04210	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J5276_RS04220	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J5276_RS04225	COG0081	regulation of translation
J5276_RS04230	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5276_RS04235	COG0222	ribosome binding
J5276_RS04245	COG0085	RNA polymerase activity
J5276_RS04250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5276_RS04265	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J5276_RS04270	COG0049	tRNA binding
J5276_RS04275	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5276_RS04280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5276_RS04285	COG0051	transcription antitermination factor activity, RNA binding
J5276_RS04290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5276_RS04295	COG0088	Forms part of the polypeptide exit tunnel
J5276_RS04300	COG0089	rRNA binding
J5276_RS04305	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5276_RS04310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5276_RS04315	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5276_RS04320	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5276_RS04325	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J5276_RS04330	COG0255	Belongs to the universal ribosomal protein uL29 family
J5276_RS04335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5276_RS04340	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5276_RS04345	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5276_RS04350	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J5276_RS04355	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5276_RS04360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J5276_RS04365	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5276_RS04370	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J5276_RS04375	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J5276_RS04380	COG1841	ribosomal large subunit assembly
J5276_RS04385	COG0200	Binds to the 23S rRNA
J5276_RS04390	COG0201	protein transport
J5276_RS04395	COG0563	adenylate kinase activity
J5276_RS04400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5276_RS04405	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5276_RS04410	COG0202	RNA polymerase activity
J5276_RS04415	COG0203	ribosomal protein L17
J5276_RS04425	COG3739	integral membrane protein
J5276_RS04435	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
J5276_RS04440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J5276_RS04445	COG0129	dihydroxy-acid dehydratase activity
J5276_RS04460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5276_RS04465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5276_RS04475	COG0840	transmembrane signaling receptor activity
J5276_RS04475	COG0840	transmembrane signaling receptor activity
J5276_RS04485	COG0730	response to heat
J5276_RS04490	COG1131	(ABC) transporter
J5276_RS04495	COG0842	Transport permease protein
J5276_RS04510	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J5276_RS04515	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J5276_RS04525	COG2202	Pas domain
J5276_RS04525	COG2205	protein histidine kinase activity
J5276_RS04535	COG1573	uracil-dna glycosylase
J5276_RS04540	COG1522	sequence-specific DNA binding
J5276_RS04545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5276_RS04555	COG5425	PFAM Usg family protein
J5276_RS04565	COG4215	(ABC) transporter
J5276_RS04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS04580	COG2313	pseudouridylate synthase activity
J5276_RS04585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_RS04590	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J5276_RS04595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5276_RS04610	COG0538	isocitrate dehydrogenase activity
J5276_RS04620	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J5276_RS04625	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J5276_RS04635	COG1280	lysine exporter protein (LysE YggA)
J5276_RS04655	COG0861	Integral membrane protein TerC family
J5276_RS04660	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J5276_RS04665	COG2066	Belongs to the glutaminase family
J5276_RS04670	COG0037	tRNA processing
J5276_RS04675	COG0483	inositol monophosphate 1-phosphatase activity
J5276_RS04680	COG0483	inositol monophosphate 1-phosphatase activity
J5276_RS04685	COG2814	Major facilitator Superfamily
J5276_RS04690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J5276_RS04710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5276_RS04720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5276_RS04735	COG0047	phosphoribosylformylglycinamidine synthase activity
J5276_RS04740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5276_RS04745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5276_RS04755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J5276_RS04780	COG0513	Belongs to the DEAD box helicase family
J5276_RS04785	COG0739	heme binding
J5276_RS04790	COG2833	Protein of unknown function (DUF455)
J5276_RS04795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J5276_RS04805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5276_RS04810	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J5276_RS04815	COG2945	thiolester hydrolase activity
J5276_RS04820	COG1104	cysteine desulfurase activity
J5276_RS04825	COG0719	Fe-S assembly protein
J5276_RS04830	COG0396	ATPase activity
J5276_RS04835	COG0719	Fe-S assembly protein
J5276_RS04840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J5276_RS04845	COG2151	metal-sulfur cluster biosynthetic enzyme
J5276_RS04860	COG0577	efflux transmembrane transporter activity
J5276_RS04860	COG1136	(ABC) transporter
J5276_RS04865	COG0577	efflux transmembrane transporter activity
J5276_RS04865	COG1136	(ABC) transporter
J5276_RS04920	COG1278	Cold shock
J5276_RS04925	COG0346	lactoylglutathione lyase activity
J5276_RS05080	COG1061	Type III restriction enzyme res subunit
J5276_RS05180	COG0616	signal peptide processing
J5276_RS05240	COG3685	Protein conserved in bacteria
J5276_RS05375	COG0785	Cytochrome C biogenesis protein
J5276_RS05380	COG0679	Auxin Efflux Carrier
J5276_RS05385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5276_RS05390	COG1183	phosphatidylcholine synthase activity
J5276_RS05395	COG3845	ABC transporter
J5276_RS05400	COG4603	Belongs to the binding-protein-dependent transport system permease family
J5276_RS05405	COG1079	Belongs to the binding-protein-dependent transport system permease family
J5276_RS05415	COG2186	Transcriptional regulator
J5276_RS05420	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5276_RS05425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J5276_RS05455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5276_RS05465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5276_RS05475	COG0697	spore germination
J5276_RS05505	COG0174	glutamine synthetase
J5276_RS05510	COG0347	Belongs to the P(II) protein family
J5276_RS05520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5276_RS05520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5276_RS05535	COG0583	DNA-binding transcription factor activity
J5276_RS05570	COG1760	l-serine dehydratase
J5276_RS05600	COG0516	GMP reductase activity
J5276_RS05600	COG0517	IMP dehydrogenase activity
J5276_RS05605	COG1752	Esterase of the alpha-beta hydrolase superfamily
J5276_RS05610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5276_RS05615	COG0302	gtp cyclohydrolase
J5276_RS05625	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5276_RS05635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J5276_RS05670	COG0628	permease
J5276_RS05675	COG1132	(ABC) transporter
J5276_RS05685	COG1914	H( )-stimulated, divalent metal cation uptake system
J5276_RS05700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5276_RS05710	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J5276_RS05715	COG0589	response to stress
J5276_RS05720	COG1058	Belongs to the CinA family
J5276_RS05720	COG1546	Belongs to the CinA family
J5276_RS05725	COG0655	NAD(P)H dehydrogenase (quinone) activity
J5276_RS05910	COG1372	Participates in initiation and elongation during chromosome replication
J5276_RS05910	COG0305	Participates in initiation and elongation during chromosome replication
J5276_RS05935	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5276_RS05985	COG5410	chromosome segregation
J5276_RS06080	COG3645	SOS response
J5276_RS06080	COG3646	Phage regulatory protein
J5276_RS06120	COG0318	PFAM AMP-dependent synthetase and ligase
J5276_RS06125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5276_RS06285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J5276_RS06295	COG0525	valine-tRNA ligase activity
J5276_RS06320	COG0316	Belongs to the HesB IscA family
J5276_RS06325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5276_RS06330	COG0018	arginyl-trna synthetase
J5276_RS06340	COG1472	Belongs to the glycosyl hydrolase 3 family
J5276_RS06345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J5276_RS06350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J5276_RS06355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5276_RS06360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5276_RS06365	COG0805	protein transport
J5276_RS06370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5276_RS06375	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J5276_RS06380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J5276_RS06385	COG0739	heme binding
J5276_RS06390	COG1763	Mo-molybdopterin cofactor biosynthetic process
J5276_RS06395	COG0746	molybdenum cofactor guanylyltransferase activity
J5276_RS06400	COG2814	Major facilitator Superfamily
J5276_RS06410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J5276_RS06420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5276_RS06420	COG0475	glutathione-regulated potassium exporter activity
J5276_RS06430	COG3706	GGDEF domain
J5276_RS06435	COG0303	'Molybdopterin
J5276_RS06440	COG0315	cyclic pyranopterin monophosphate synthase activity
J5276_RS06445	COG0134	indole-3-glycerol-phosphate synthase activity
J5276_RS06450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5276_RS06465	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J5276_RS06480	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5276_RS06485	COG0343	queuine tRNA-ribosyltransferase activity
J5276_RS06490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5276_RS06490	COG0512	Glutamine amidotransferase of anthranilate synthase
J5276_RS06515	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J5276_RS06535	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
J5276_RS06555	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5276_RS06585	COG1368	sulfuric ester hydrolase activity
J5276_RS06600	COG0823	Involved in the tonB-independent uptake of proteins
J5276_RS06605	COG0778	Nitroreductase
J5276_RS06615	COG0281	malic enzyme
J5276_RS06615	COG0280	phosphate acetyltransferase
J5276_RS06625	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_RS06630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J5276_RS06635	COG1127	ABC transporter
J5276_RS06700	COG3264	Mechanosensitive ion channel
J5276_RS06700	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J5276_RS06715	COG0745	RESPONSE REGULATOR receiver
J5276_RS06720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5276_RS06725	COG0640	Transcriptional regulator
J5276_RS06735	COG0740	serine-type endopeptidase activity
J5276_RS06740	COG0187	DNA topoisomerase II activity
J5276_RS06750	COG0149	triose-phosphate isomerase activity
J5276_RS06760	COG0504	CTP synthase activity
J5276_RS06770	COG0114	fumarate hydratase activity
J5276_RS06780	COG0546	phosphoglycolate phosphatase activity
J5276_RS06785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J5276_RS06800	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
J5276_RS06815	COG2003	Belongs to the UPF0758 family
J5276_RS06820	COG0024	Methionine aminopeptidase
J5276_RS06825	COG1489	DNA binding
J5276_RS06830	COG3243	poly(R)-hydroxyalkanoic acid synthase
J5276_RS06845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5276_RS06850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5276_RS06855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5276_RS06865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5276_RS06895	COG0436	Aminotransferase
J5276_RS06910	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5276_RS06925	COG1126	abc transporter atp-binding protein
J5276_RS06930	COG0765	amino acid transport
J5276_RS06935	COG4597	amino acid ABC transporter
J5276_RS06940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS06945	COG0626	cystathionine gamma-synthase activity
J5276_RS06960	COG0596	Alpha beta hydrolase
J5276_RS06975	COG2124	cytochrome p450
J5276_RS06995	COG1862	Preprotein translocase
J5276_RS07025	COG1064	alcohol dehydrogenase
J5276_RS07030	COG0321	lipoyl(octanoyl) transferase activity
J5276_RS07055	COG0242	peptide deformylase activity
J5276_RS07065	COG0243	molybdopterin cofactor binding
J5276_RS07070	COG2239	Acts as a magnesium transporter
J5276_RS07145	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J5276_RS07155	COG0667	Aldo Keto reductase
J5276_RS07175	COG1121	(ABC) transporter
J5276_RS07180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5276_RS07195	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5276_RS07200	COG3685	Protein conserved in bacteria
J5276_RS07210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5276_RS07220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5276_RS07225	COG0629	single-stranded DNA binding
J5276_RS07230	COG0517	IMP dehydrogenase activity
J5276_RS07230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J5276_RS07230	COG0617	tRNA 3'-terminal CCA addition
J5276_RS07235	COG2095	MarC family integral membrane protein
J5276_RS07240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J5276_RS07290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J5276_RS07300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5276_RS07305	COG0084	hydrolase, TatD family'
J5276_RS07310	COG0321	lipoyl(octanoyl) transferase activity
J5276_RS07310	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J5276_RS07320	COG2226	methyltransferase
J5276_RS07330	COG0328	RNA-DNA hybrid ribonuclease activity
J5276_RS07335	COG1879	ABC-type sugar transport system periplasmic component
J5276_RS07340	COG1129	ABC transporter
J5276_RS07345	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS07350	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS07355	COG1609	Transcriptional regulator
J5276_RS07365	COG0673	inositol 2-dehydrogenase activity
J5276_RS07395	COG0784	Response regulator, receiver
J5276_RS07395	COG4191	Histidine kinase
J5276_RS07400	COG2202	Pas domain
J5276_RS07400	COG3920	Histidine kinase
J5276_RS07405	COG0784	Response regulator, receiver
J5276_RS07410	COG0784	Response regulator, receiver
J5276_RS07410	COG4191	Histidine kinase
J5276_RS07415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_RS07430	COG2828	Protein conserved in bacteria
J5276_RS07435	COG0583	DNA-binding transcription factor activity
J5276_RS07445	COG2801	Transposase and inactivated derivatives
J5276_RS07480	COG0625	glutathione transferase activity
J5276_RS07485	COG0450	alkyl hydroperoxide reductase
J5276_RS07495	COG1671	Belongs to the UPF0178 family
J5276_RS07505	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
J5276_RS07510	COG0251	oxidation-reduction process
J5276_RS07515	COG1309	transcriptional regulator
J5276_RS07530	COG0546	phosphoglycolate phosphatase activity
J5276_RS07535	COG0564	pseudouridine synthase activity
J5276_RS07540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5276_RS07570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J5276_RS07575	COG0509	glycine decarboxylation via glycine cleavage system
J5276_RS07580	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5276_RS07580	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5276_RS07620	COG1648	precorrin-2 dehydrogenase activity
J5276_RS07620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5276_RS07630	COG3956	TIGRFAM MazG family protein
J5276_RS07635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5276_RS07640	COG1923	regulation of RNA biosynthetic process
J5276_RS07645	COG0569	domain protein
J5276_RS07650	COG2204	response regulator
J5276_RS07655	COG5000	phosphorelay sensor kinase activity
J5276_RS07660	COG2204	response regulator
J5276_RS07665	COG3852	Histidine kinase
J5276_RS07675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5276_RS07675	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5276_RS07680	COG1546	Belongs to the CinA family
J5276_RS07685	COG2867	negative regulation of translational initiation
J5276_RS07705	COG0697	spore germination
J5276_RS07710	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5276_RS07720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5276_RS07730	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5276_RS07735	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5276_RS07735	COG0022	dehydrogenase e1 component
J5276_RS07740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J5276_RS07750	COG0148	phosphopyruvate hydratase activity
J5276_RS07755	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5276_RS07765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J5276_RS07780	COG0582	viral genome integration into host DNA
J5276_RS07805	COG1802	Transcriptional regulator
J5276_RS07805	COG4626	Terminase
J5276_RS07850	COG0372	Belongs to the citrate synthase family
J5276_RS07855	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5276_RS07860	COG3494	Protein of unknown function (DUF1009)
J5276_RS07865	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5276_RS07870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5276_RS07875	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5276_RS07880	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5276_RS07885	COG0750	zinc metalloprotease
J5276_RS07895	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J5276_RS07900	COG0233	cytoplasmic translational termination
J5276_RS07905	COG0528	UMP kinase activity
J5276_RS07910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5276_RS07915	COG0052	Belongs to the universal ribosomal protein uS2 family
J5276_RS07940	COG0537	adenosine 5'-monophosphoramidase activity
J5276_RS07975	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J5276_RS08005	COG3106	COG3106 Predicted ATPase
J5276_RS08010	COG3768	UPF0283 membrane protein
J5276_RS08020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5276_RS08025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J5276_RS08030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J5276_RS08040	COG0633	Ferredoxin
J5276_RS08055	COG0384	phenazine biosynthesis protein PhzF
J5276_RS08060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J5276_RS08080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5276_RS08090	COG1530	ribonuclease E activity
J5276_RS08095	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS08115	COG0436	Aminotransferase
J5276_RS08125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J5276_RS08130	COG0511	ligase activity, forming carbon-carbon bonds
J5276_RS08140	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5276_RS08155	COG0456	acetyltransferase
J5276_RS08165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5276_RS08180	COG3811	Belongs to the UPF0386 family
J5276_RS08185	COG0154	amidase activity
J5276_RS08190	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5276_RS08195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
J5276_RS08200	COG2824	Alkylphosphonate utilization operon protein PhnA
J5276_RS08205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J5276_RS08225	COG0456	acetyltransferase
J5276_RS08230	COG1960	acyl-CoA dehydrogenase activity
J5276_RS08235	COG0540	Belongs to the ATCase OTCase family
J5276_RS08245	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J5276_RS08250	COG0758	DNA mediated transformation
J5276_RS08260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J5276_RS08265	COG0557	exoribonuclease II activity
J5276_RS08280	COG0477	Major facilitator Superfamily
J5276_RS08285	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J5276_RS08295	COG0784	Response regulator, receiver
J5276_RS08305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5276_RS08320	COG1136	(ABC) transporter
J5276_RS08330	COG0442	prolyl-tRNA aminoacylation
J5276_RS08345	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J5276_RS08345	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J5276_RS08350	COG1007	ATP synthesis coupled electron transport
J5276_RS08365	COG0713	ATP synthesis coupled electron transport
J5276_RS08375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5276_RS08380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J5276_RS08390	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J5276_RS08395	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J5276_RS08405	COG0649	NAD binding
J5276_RS08415	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5276_RS08420	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5276_RS08425	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5276_RS08460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J5276_RS08465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J5276_RS08470	COG0740	serine-type endopeptidase activity
J5276_RS08475	COG2199	diguanylate cyclase activity
J5276_RS08495	COG1832	CoA-binding protein
J5276_RS08510	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5276_RS08515	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5276_RS08520	COG0010	Belongs to the arginase family
J5276_RS08525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5276_RS08535	COG1612	heme a metabolic process
J5276_RS08605	COG1528	Iron-storage protein
J5276_RS08615	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J5276_RS08620	COG4139	cobalamin transport
J5276_RS08635	COG1238	metal cluster binding
J5276_RS08640	COG3932	Exopolysaccharide synthesis, ExoD
J5276_RS08685	COG1196	nuclear chromosome segregation
J5276_RS08770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5276_RS08780	COG0415	Belongs to the DNA photolyase family
J5276_RS08795	COG2897	thiosulfate sulfurtransferase activity
J5276_RS08820	COG0737	Belongs to the 5'-nucleotidase family
J5276_RS08830	COG0583	DNA-binding transcription factor activity
J5276_RS08835	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J5276_RS08850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5276_RS08855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5276_RS08865	COG0747	negative chemotaxis
J5276_RS08875	COG0444	Belongs to the ABC transporter superfamily
J5276_RS08880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS08885	COG0601	transmembrane transport
J5276_RS08920	COG0776	regulation of translation
J5276_RS08925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5276_RS08930	COG0416	fatty acid biosynthetic process
J5276_RS08950	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J5276_RS08955	COG2814	Major facilitator Superfamily
J5276_RS08960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5276_RS08965	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J5276_RS08970	COG1280	lysine exporter protein (LysE YggA)
J5276_RS08980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5276_RS08980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5276_RS08985	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5276_RS08990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5276_RS09010	COG0113	porphobilinogen synthase activity
J5276_RS09020	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J5276_RS09025	COG2336	PFAM SpoVT AbrB
J5276_RS09030	COG3654	unkown
J5276_RS09035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J5276_RS09045	COG0659	secondary active sulfate transmembrane transporter activity
J5276_RS09050	COG4452	Inner membrane protein CreD
J5276_RS09055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5276_RS09060	COG0477	Major facilitator Superfamily
J5276_RS09065	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J5276_RS09075	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
J5276_RS09100	COG0248	Ppx GppA phosphatase
J5276_RS09105	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5276_RS09115	COG0628	permease
J5276_RS09120	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5276_RS09125	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5276_RS09140	COG0243	molybdopterin cofactor binding
J5276_RS09145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J5276_RS09160	COG0625	glutathione transferase activity
J5276_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS09175	COG0322	excinuclease ABC activity
J5276_RS09180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J5276_RS09190	COG0314	molybdopterin synthase activity
J5276_RS09210	COG0105	UTP biosynthetic process
J5276_RS09220	COG3706	GGDEF domain
J5276_RS09225	COG0488	(ABC) transporter
J5276_RS09250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J5276_RS09265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J5276_RS09275	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5276_RS09280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5276_RS09290	COG0194	GDP metabolic process
J5276_RS09295	COG1561	YicC-like family, N-terminal region
J5276_RS09300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J5276_RS09305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5276_RS09310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5276_RS09320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J5276_RS09325	COG0667	Aldo Keto reductase
J5276_RS09330	COG0360	Binds together with S18 to 16S ribosomal RNA
J5276_RS09335	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J5276_RS09345	COG0359	binds to the 23S rRNA
J5276_RS09370	COG0305	Participates in initiation and elongation during chromosome replication
J5276_RS09380	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J5276_RS09390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5276_RS09405	COG1286	toxin biosynthetic process
J5276_RS09410	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J5276_RS09415	COG4221	oxidoreductase activity
J5276_RS09420	COG0215	cysteine-tRNA ligase activity
J5276_RS09425	COG2852	Protein conserved in bacteria
J5276_RS09470	COG5265	(ABC) transporter
J5276_RS09475	COG0688	phosphatidylethanolamine metabolic process
J5276_RS09480	COG1183	phosphatidylcholine synthase activity
J5276_RS09495	COG1742	UPF0060 membrane protein
J5276_RS09520	COG0354	folic acid binding
J5276_RS09525	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J5276_RS09535	COG0668	transmembrane transport
J5276_RS09540	COG3443	Belongs to the bacterial solute-binding protein 9 family
J5276_RS09545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_RS09560	COG0346	lactoylglutathione lyase activity
J5276_RS09570	COG1418	mRNA catabolic process
J5276_RS09580	COG2226	methyltransferase
J5276_RS09590	COG1381	Involved in DNA repair and RecF pathway recombination
J5276_RS09595	COG0784	Response regulator, receiver
J5276_RS09600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5276_RS09605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J5276_RS09610	COG0571	ribonuclease III activity
J5276_RS09615	COG0681	Belongs to the peptidase S26 family
J5276_RS09620	COG0736	holo-[acyl-carrier-protein] synthase activity
J5276_RS09640	COG1758	RNA polymerase activity
J5276_RS09650	COG0840	transmembrane signaling receptor activity
J5276_RS09655	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5276_RS09660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_RS09665	COG0741	lytic transglycosylase activity
J5276_RS09690	COG0582	viral genome integration into host DNA
J5276_RS09760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5276_RS09790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J5276_RS09820	COG2814	Major facilitator Superfamily
J5276_RS09825	COG2239	Acts as a magnesium transporter
J5276_RS09830	COG1968	undecaprenyl-diphosphatase activity
J5276_RS09835	COG1733	regulation of RNA biosynthetic process
J5276_RS09840	COG0604	alcohol dehydrogenase
J5276_RS09865	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS09875	COG0443	Heat shock 70 kDa protein
J5276_RS09895	COG0308	aminopeptidase N
J5276_RS09905	COG2202	Pas domain
J5276_RS09905	COG2205	protein histidine kinase activity
J5276_RS09910	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J5276_RS09920	COG3011	Protein conserved in bacteria
J5276_RS09930	COG0745	RESPONSE REGULATOR receiver
J5276_RS09935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5276_RS09940	COG3088	subunit of a heme lyase
J5276_RS09945	COG1138	Cytochrome C-type biogenesis protein
J5276_RS09950	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J5276_RS09955	COG4235	cytochrome complex assembly
J5276_RS10060	COG4695	Portal protein
J5276_RS10110	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J5276_RS10115	COG3920	Histidine kinase
J5276_RS10115	COG2202	Pas domain
J5276_RS10120	COG1621	beta-fructofuranosidase activity
J5276_RS10155	COG2983	Belongs to the UPF0260 family
J5276_RS10160	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5276_RS10215	COG2205	protein histidine kinase activity
J5276_RS10225	COG2166	iron-sulfur cluster assembly
J5276_RS10240	COG4957	zinc ion binding
J5276_RS10245	COG1320	monovalent cation:proton antiporter activity
J5276_RS10250	COG2212	antiporter activity
J5276_RS10255	COG1863	multisubunit Na H antiporter MnhE subunit
J5276_RS10260	COG0651	ATP synthesis coupled electron transport
J5276_RS10265	COG1006	Multisubunit Na H antiporter MnhC subunit
J5276_RS10270	COG2111	Na H antiporter
J5276_RS10275	COG2111	Na H antiporter
J5276_RS10275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J5276_RS10280	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5276_RS10285	COG1280	lysine exporter protein (LysE YggA)
J5276_RS10295	COG1272	protein, Hemolysin III
J5276_RS10310	COG2514	catechol 2,3-dioxygenase activity
J5276_RS10320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5276_RS10320	COG2169	Transcriptional regulator
J5276_RS10330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_RS10350	COG4176	ABC-type proline glycine betaine transport system permease component
J5276_RS10380	COG0789	Transcriptional regulator
J5276_RS10410	COG2010	Cytochrome c
J5276_RS10415	COG3909	cytochrome
J5276_RS10435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J5276_RS10450	COG0583	DNA-binding transcription factor activity
J5276_RS10455	COG0840	transmembrane signaling receptor activity
J5276_RS10460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J5276_RS10465	COG4106	trans-aconitate 2-methyltransferase activity
J5276_RS10475	COG2378	regulation of single-species biofilm formation
J5276_RS10480	COG0656	L-ascorbic acid biosynthetic process
J5276_RS10485	COG1280	lysine exporter protein (LysE YggA)
J5276_RS10495	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
J5276_RS10500	COG1733	regulation of RNA biosynthetic process
J5276_RS10510	COG0433	COG0433 Predicted ATPase
J5276_RS10520	COG4221	oxidoreductase activity
J5276_RS10525	COG0583	DNA-binding transcription factor activity
J5276_RS10560	COG0488	(ABC) transporter
J5276_RS10575	COG1764	response to oxidative stress
J5276_RS10580	COG1846	Transcriptional regulator
J5276_RS10595	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_RS10600	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_RS10615	COG1793	dna ligase
J5276_RS10615	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5276_RS10625	COG0477	Major facilitator Superfamily
J5276_RS10670	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
J5276_RS10675	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS10680	COG1309	transcriptional regulator
J5276_RS10690	COG2203	Gaf domain
J5276_RS10690	COG2200	EAL domain
J5276_RS10690	COG2199	diguanylate cyclase activity
J5276_RS10700	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5276_RS10705	COG4208	sulfate ABC transporter
J5276_RS10710	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J5276_RS10715	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J5276_RS10720	COG1959	2 iron, 2 sulfur cluster binding
J5276_RS10725	COG0175	sulfate reduction
J5276_RS10730	COG0175	sulfate reduction
J5276_RS10735	COG2895	sulfate adenylyltransferase (ATP) activity
J5276_RS10765	COG0579	oxidoreductase
J5276_RS10785	COG1823	symporter activity
J5276_RS10800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5276_RS10800	COG0574	Belongs to the PEP-utilizing enzyme family
J5276_RS10805	COG2514	catechol 2,3-dioxygenase activity
J5276_RS10810	COG1196	nuclear chromosome segregation
J5276_RS10815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J5276_RS10835	COG2189	Belongs to the N(4) N(6)-methyltransferase family
J5276_RS10855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5276_RS10870	COG0612	Peptidase, M16
J5276_RS10875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5276_RS10895	COG1678	Uncharacterized ACR, COG1678
J5276_RS10905	COG0678	peroxiredoxin activity
J5276_RS10905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J5276_RS10915	COG0328	RNA-DNA hybrid ribonuclease activity
J5276_RS10920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J5276_RS10925	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5276_RS10930	COG3346	SURF1 family
J5276_RS10945	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J5276_RS10950	COG0109	protoheme IX farnesyltransferase activity
J5276_RS10955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J5276_RS10970	COG0312	modulator of DNA gyrase
J5276_RS10980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5276_RS10995	COG0259	pyridoxamine-phosphate oxidase activity
J5276_RS11010	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J5276_RS11030	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5276_RS11035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5276_RS11035	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5276_RS11040	COG3214	Protein conserved in bacteria
J5276_RS11045	COG1122	ATPase activity
J5276_RS11050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J5276_RS11055	COG1268	BioY protein
J5276_RS11060	COG0123	including yeast histone deacetylase and acetoin utilization protein
J5276_RS11065	COG1722	exodeoxyribonuclease VII activity
J5276_RS11070	COG1741	Belongs to the pirin family
J5276_RS11075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5276_RS11100	COG0840	transmembrane signaling receptor activity
J5276_RS11105	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J5276_RS11110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J5276_RS11125	COG1960	acyl-CoA dehydrogenase activity
J5276_RS11150	COG4638	Rieske (2fe-2S)
J5276_RS11160	COG0009	L-threonylcarbamoyladenylate synthase
J5276_RS11180	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J5276_RS11190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J5276_RS11195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J5276_RS11205	COG0356	it plays a direct role in the translocation of protons across the membrane
J5276_RS11220	COG3158	transport of potassium into the cell
J5276_RS11225	COG0598	Magnesium transport protein CorA
J5276_RS11240	COG2197	response regulator
J5276_RS11250	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS11255	COG3734	2-keto-3-deoxy-galactonokinase
J5276_RS11260	COG0800	Aldolase
J5276_RS11265	COG3386	PFAM SMP-30 Gluconolaconase
J5276_RS11270	COG5001	Diguanylate cyclase
J5276_RS11270	COG3300	MHYT domain
J5276_RS11275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS11275	COG2205	protein histidine kinase activity
J5276_RS11280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5276_RS11290	COG1663	tetraacyldisaccharide 4'-kinase activity
J5276_RS11300	COG1519	Transferase
J5276_RS11315	COG0312	modulator of DNA gyrase
J5276_RS11325	COG1752	Esterase of the alpha-beta hydrolase superfamily
J5276_RS11330	COG0742	ribosomal rna small subunit methyltransferase
J5276_RS11335	COG1187	pseudouridine synthase activity
J5276_RS11340	COG0590	tRNA wobble adenosine to inosine editing
J5276_RS11350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5276_RS11355	COG0196	riboflavin kinase activity
J5276_RS11365	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5276_RS11370	COG0459	protein refolding
J5276_RS11380	COG2259	Doxx family
J5276_RS11385	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J5276_RS11390	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
J5276_RS11400	COG0124	histidyl-tRNA synthetase
J5276_RS11420	COG0583	DNA-binding transcription factor activity
J5276_RS11425	COG2855	membrane
J5276_RS11435	COG2818	Glycosylase
J5276_RS11440	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_RS11450	COG0247	lactate metabolic process
J5276_RS11455	COG0277	FAD linked oxidase domain protein
J5276_RS11460	COG0277	FAD linked oxidase domain protein
J5276_RS11465	COG0583	DNA-binding transcription factor activity
J5276_RS11475	COG2186	Transcriptional regulator
J5276_RS11480	COG0438	transferase activity, transferring glycosyl groups
J5276_RS11485	COG0561	phosphatase activity
J5276_RS11495	COG0306	phosphate transporter
J5276_RS11515	COG0583	DNA-binding transcription factor activity
J5276_RS11540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J5276_RS11545	COG2183	response to ionizing radiation
J5276_RS11550	COG0151	Belongs to the GarS family
J5276_RS11560	COG0840	transmembrane signaling receptor activity
J5276_RS11580	COG0751	glycine-tRNA ligase activity
J5276_RS11590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5276_RS11595	COG1704	LemA family
J5276_RS11600	COG0752	glycyl-tRNA synthetase alpha subunit
J5276_RS11625	COG0142	geranyltranstransferase activity
J5276_RS11635	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J5276_RS11640	COG0521	Mo-molybdopterin cofactor biosynthetic process
J5276_RS11670	COG0477	Major facilitator Superfamily
J5276_RS11675	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J5276_RS11680	COG0248	Ppx GppA phosphatase
J5276_RS11690	COG2205	protein histidine kinase activity
J5276_RS11700	COG1177	transmembrane transport
J5276_RS11705	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_RS11710	COG3842	ATPase activity
J5276_RS11725	COG2224	Isocitrate lyase
J5276_RS11745	COG2081	HI0933 family
J5276_RS11755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS11765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J5276_RS11770	COG0363	glucosamine-6-phosphate deaminase activity
J5276_RS11775	COG0129	dihydroxy-acid dehydratase activity
J5276_RS11790	COG3842	ATPase activity
J5276_RS11795	COG0366	Alpha amylase catalytic
J5276_RS11800	COG0395	ABC-type sugar transport system, permease component
J5276_RS11805	COG1175	transmembrane transport
J5276_RS11810	COG1653	transport
J5276_RS11815	COG1609	Transcriptional regulator
J5276_RS11820	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5276_RS11860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J5276_RS11870	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J5276_RS11875	COG5443	negative regulation of bacterial-type flagellum assembly
J5276_RS11895	COG1749	Flagellar hook protein flgE
J5276_RS11920	COG1360	Flagellar Motor Protein
J5276_RS11940	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J5276_RS11945	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J5276_RS11950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J5276_RS11955	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J5276_RS11960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J5276_RS11970	COG4786	Flagellar basal body rod
J5276_RS11975	COG1157	protein secretion by the type III secretion system
J5276_RS11985	COG1815	bacterial-type flagellum-dependent cell motility
J5276_RS11990	COG1558	bacterial-type flagellum-dependent cell motility
J5276_RS11995	COG1677	Flagellar hook-basal body complex protein FliE
J5276_RS12000	COG4786	Flagellar basal body rod
J5276_RS12005	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
J5276_RS12010	COG1706	bacterial-type flagellum-dependent cell motility
J5276_RS12020	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J5276_RS12030	COG1338	Plays a role in the flagellum-specific transport system
J5276_RS12045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5276_RS12060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5276_RS12070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5276_RS12075	COG5328	Belongs to the UPF0262 family
J5276_RS12085	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5276_RS12090	COG0424	maF-like protein
J5276_RS12095	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J5276_RS12110	COG0436	Aminotransferase
J5276_RS12115	COG1970	mechanosensitive ion channel activity
J5276_RS12165	COG2801	Transposase and inactivated derivatives
J5276_RS12265	COG4373	Mu-like prophage FluMu protein gp28
J5276_RS12270	COG4383	Mu-like prophage protein gp29
J5276_RS12295	COG4397	Mu-like prophage major head subunit gpT
J5276_RS12365	COG3299	homolog of phage Mu protein gp47
J5276_RS12405	COG0840	transmembrane signaling receptor activity
J5276_RS12405	COG2972	Histidine kinase
J5276_RS12415	COG2771	luxR family
J5276_RS12420	COG1766	The M ring may be actively involved in energy transduction
J5276_RS12430	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
J5276_RS12435	COG0745	RESPONSE REGULATOR receiver
J5276_RS12440	COG2201	protein-glutamate methylesterase activity
J5276_RS12445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J5276_RS12450	COG0643	Histidine kinase
J5276_RS12450	COG2198	Histidine kinase
J5276_RS12455	COG0745	RESPONSE REGULATOR receiver
J5276_RS12465	COG0840	transmembrane signaling receptor activity
J5276_RS12475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J5276_RS12475	COG2111	Na H antiporter
J5276_RS12480	COG1006	Multisubunit Na H antiporter MnhC subunit
J5276_RS12485	COG0651	ATP synthesis coupled electron transport
J5276_RS12490	COG1863	multisubunit Na H antiporter MnhE subunit
J5276_RS12495	COG2212	antiporter activity
J5276_RS12500	COG1320	monovalent cation:proton antiporter activity
J5276_RS12515	COG1024	Enoyl-CoA hydratase
J5276_RS12515	COG1250	3-hydroxyacyl-CoA dehydrogenase
J5276_RS12520	COG0183	Belongs to the thiolase family
J5276_RS12525	COG1960	acyl-CoA dehydrogenase activity
J5276_RS12555	COG1201	RNA secondary structure unwinding
J5276_RS12560	COG1959	2 iron, 2 sulfur cluster binding
J5276_RS12565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J5276_RS12580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5276_RS12595	COG0167	dihydroorotate dehydrogenase activity
J5276_RS12645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J5276_RS12655	COG0717	Belongs to the dCTP deaminase family
J5276_RS12665	COG2967	ApaG domain
J5276_RS12675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5276_RS12680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5276_RS12690	COG0745	RESPONSE REGULATOR receiver
J5276_RS12695	COG0704	Plays a role in the regulation of phosphate uptake
J5276_RS12700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5276_RS12710	COG0573	inorganic phosphate transmembrane transporter activity
J5276_RS12715	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J5276_RS12720	COG5002	protein histidine kinase activity
J5276_RS12725	COG2326	polyphosphate kinase activity
J5276_RS12765	COG4774	siderophore transport
J5276_RS12770	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J5276_RS12775	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_RS12780	COG3842	ATPase activity
J5276_RS12785	COG0318	PFAM AMP-dependent synthetase and ligase
J5276_RS12790	COG0166	Belongs to the GPI family
J5276_RS12795	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5276_RS12815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5276_RS12820	COG0418	dihydroorotase activity
J5276_RS12825	COG3938	Belongs to the proline racemase family
J5276_RS12835	COG0427	acetyl-CoA hydrolase
J5276_RS12850	COG0395	ABC-type sugar transport system, permease component
J5276_RS12855	COG1175	transmembrane transport
J5276_RS12860	COG3842	ATPase activity
J5276_RS12865	COG2226	methyltransferase
J5276_RS12880	COG0840	transmembrane signaling receptor activity
J5276_RS12885	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J5276_RS12890	COG0594	ribonuclease P activity
J5276_RS12895	COG0706	membrane insertase activity
J5276_RS12900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J5276_RS12910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5276_RS12935	COG0071	Belongs to the small heat shock protein (HSP20) family
J5276_RS12945	COG0840	transmembrane signaling receptor activity
J5276_RS12955	COG2171	N-acyltransferase activity
J5276_RS12960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5276_RS12970	COG0101	tRNA pseudouridine synthase activity
J5276_RS12975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5276_RS12980	COG0242	peptide deformylase activity
J5276_RS12990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_RS12995	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5276_RS13000	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5276_RS13005	COG1396	sequence-specific DNA binding
J5276_RS13010	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J5276_RS13020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5276_RS13025	COG1702	phosphate starvation-inducible protein PhoH
J5276_RS13030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5276_RS13045	COG0456	acetyltransferase
J5276_RS13045	COG1214	PFAM Peptidase M22, glycoprotease
J5276_RS13050	COG1214	PFAM Peptidase M22, glycoprotease
J5276_RS13055	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J5276_RS13065	COG0180	Tryptophanyl-tRNA synthetase
J5276_RS13075	COG0728	peptidoglycan biosynthetic process
J5276_RS13080	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J5276_RS13085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5276_RS13100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J5276_RS13105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5276_RS13120	COG0776	regulation of translation
J5276_RS13125	COG0616	signal peptide processing
J5276_RS13135	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J5276_RS13140	COG1137	ATPase activity
J5276_RS13150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J5276_RS13155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5276_RS13160	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5276_RS13165	COG1420	regulation of RNA biosynthetic process
J5276_RS13170	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J5276_RS13175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5276_RS13180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5276_RS13185	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5276_RS13190	COG0268	Binds directly to 16S ribosomal RNA
J5276_RS13195	COG1024	Enoyl-CoA hydratase
J5276_RS13200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J5276_RS13205	COG2226	methyltransferase
J5276_RS13210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J5276_RS13225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5276_RS13230	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J5276_RS13235	COG0756	dUTP diphosphatase activity
J5276_RS13240	COG1280	lysine exporter protein (LysE YggA)
J5276_RS13245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J5276_RS13255	COG0189	ligase activity
J5276_RS13265	COG3842	ATPase activity
J5276_RS13270	COG0395	ABC-type sugar transport system, permease component
J5276_RS13275	COG1175	transmembrane transport
J5276_RS13290	COG0792	nuclease activity
J5276_RS13295	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5276_RS13305	COG3963	phosphatidate phosphatase activity
J5276_RS13315	COG0284	orotidine-5'-phosphate decarboxylase activity
J5276_RS13330	COG1968	undecaprenyl-diphosphatase activity
J5276_RS13340	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5276_RS13350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J5276_RS13380	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
J5276_RS13395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5276_RS13395	COG0519	Catalyzes the synthesis of GMP from XMP
J5276_RS13415	COG0477	Major facilitator Superfamily
J5276_RS13480	COG0583	DNA-binding transcription factor activity
J5276_RS13490	COG2948	multi-organism process
J5276_RS13505	COG3846	protein secretion by the type IV secretion system
J5276_RS13520	COG3451	type IV secretory pathway VirB4
J5276_RS13535	COG4962	Type ii secretion system protein e
J5276_RS13560	COG0741	lytic transglycosylase activity
J5276_RS13585	COG1192	Involved in chromosome partitioning
J5276_RS13615	COG5489	Protein of unknown function (DUF736)
J5276_RS13730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5276_RS13765	COG1393	Belongs to the ArsC family
J5276_RS13775	COG2309	aminopeptidase activity
J5276_RS13780	COG0697	spore germination
J5276_RS13785	COG1846	Transcriptional regulator
J5276_RS13795	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_RS13800	COG1570	exodeoxyribonuclease VII activity
J5276_RS13825	COG4977	sequence-specific DNA binding
J5276_RS13845	COG0667	Aldo Keto reductase
J5276_RS13850	COG0072	phenylalanine-tRNA ligase activity
J5276_RS13850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5276_RS13855	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J5276_RS13865	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J5276_RS13870	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5276_RS13875	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J5276_RS13900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5276_RS13905	COG2169	Transcriptional regulator
J5276_RS13905	COG1917	Cupin 2, conserved barrel domain protein
J5276_RS13935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5276_RS13940	COG0481	GTPase activity
J5276_RS13970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5276_RS13975	COG0697	spore germination
J5276_RS13980	COG3757	hydrolase, family 25
J5276_RS13985	COG3422	double-strand break repair
J5276_RS13990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5276_RS14030	COG4964	Belongs to the GSP D family
J5276_RS14065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J5276_RS14070	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J5276_RS14080	COG0791	NLP P60 protein
J5276_RS14095	COG0697	spore germination
J5276_RS14115	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_RS14120	COG1959	2 iron, 2 sulfur cluster binding
J5276_RS14130	COG1732	Glycine betaine
J5276_RS14135	COG1174	glycine betaine transport
J5276_RS14140	COG1125	glycine betaine transport
J5276_RS14145	COG1174	glycine betaine transport
J5276_RS14150	COG3265	gluconokinase activity
J5276_RS14155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS14160	COG0174	glutamine synthetase
J5276_RS14165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS14170	COG4172	Belongs to the ABC transporter superfamily
J5276_RS14175	COG4239	(ABC) transporter, permease
J5276_RS14180	COG4174	ABC transporter (Permease)
J5276_RS14185	COG4166	transmembrane transport
J5276_RS14190	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
J5276_RS14195	COG1803	Methylglyoxal synthase
J5276_RS14200	COG0837	glucose binding
J5276_RS14205	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5276_RS14210	COG2188	Transcriptional regulator
J5276_RS14215	COG3624	Phosphonate C-P lyase system protein PhnG
J5276_RS14220	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
J5276_RS14225	COG3626	phosphonate metabolism
J5276_RS14230	COG3627	carbon phosphorus lyase activity
J5276_RS14235	COG4107	phosphonate C-P lyase system protein PhnK
J5276_RS14240	COG4778	phosphonate C-P lyase system protein PhnL
J5276_RS14250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
J5276_RS14260	COG3639	organic phosphonate transmembrane transporter activity
J5276_RS14265	COG3639	organic phosphonate transmembrane transporter activity
J5276_RS14270	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
J5276_RS14275	COG3454	Phosphonate metabolism
J5276_RS14280	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
J5276_RS14295	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J5276_RS14305	COG0848	biopolymer transport protein
J5276_RS14325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_RS14360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5276_RS14370	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J5276_RS14385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5276_RS14390	COG0067	glutamate synthase
J5276_RS14390	COG0069	glutamate synthase activity
J5276_RS14390	COG0070	glutamate synthase
J5276_RS14395	COG0477	Major facilitator Superfamily
J5276_RS14400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J5276_RS14405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J5276_RS14410	COG1845	cytochrome c oxidase, subunit III
J5276_RS14415	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J5276_RS14425	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J5276_RS14430	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J5276_RS14435	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J5276_RS14445	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J5276_RS14450	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J5276_RS14460	COG0295	cytidine deaminase activity
J5276_RS14465	COG1079	Belongs to the binding-protein-dependent transport system permease family
J5276_RS14470	COG1079	Belongs to the binding-protein-dependent transport system permease family
J5276_RS14475	COG3845	ABC transporter
J5276_RS14480	COG1744	ABC transporter substrate-binding protein PnrA-like
J5276_RS14485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5276_RS14500	COG0443	Heat shock 70 kDa protein
J5276_RS14505	COG0484	heat shock protein binding
J5276_RS14515	COG2900	Belongs to the SlyX family
J5276_RS14545	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J5276_RS14555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5276_RS14555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5276_RS14565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5276_RS14570	COG1278	Cold shock
J5276_RS14575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5276_RS14580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5276_RS14590	COG3474	cytochrome
J5276_RS14595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5276_RS14600	COG0077	Prephenate dehydratase
J5276_RS14600	COG1605	Chorismate mutase
J5276_RS14605	COG2816	NAD+ diphosphatase activity
J5276_RS14620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J5276_RS14625	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J5276_RS14635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J5276_RS14640	COG2951	lytic endotransglycosylase activity
J5276_RS14645	COG2814	Major facilitator Superfamily
J5276_RS14650	COG0779	Required for maturation of 30S ribosomal subunits
J5276_RS14665	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5276_RS14665	COG3064	Membrane
J5276_RS14670	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5276_RS14675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5276_RS14680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5276_RS14685	COG1185	polyribonucleotide nucleotidyltransferase activity
J5276_RS14700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_RS14725	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J5276_RS14745	COG1780	Probably involved in ribonucleotide reductase function
J5276_RS14755	COG1072	(Pantothenic acid kinase))
J5276_RS14780	COG0514	ATP-dependent DNA helicase (RecQ)
J5276_RS14815	COG1643	Atp-dependent helicase
J5276_RS14825	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
J5276_RS14840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J5276_RS14850	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J5276_RS14855	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J5276_RS14860	COG0131	Imidazoleglycerol-phosphate dehydratase
J5276_RS14870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5276_RS14875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J5276_RS14880	COG0107	imidazoleglycerol-phosphate synthase activity
J5276_RS14885	COG0140	phosphoribosyl-ATP diphosphatase activity
J5276_RS14890	COG1072	(Pantothenic acid kinase))
J5276_RS14895	COG1652	LysM domain
J5276_RS14905	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J5276_RS14910	COG0745	RESPONSE REGULATOR receiver
J5276_RS14915	COG0642	Histidine kinase
J5276_RS14920	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J5276_RS14925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5276_RS14925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J5276_RS14930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5276_RS14935	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J5276_RS14940	COG2205	protein histidine kinase activity
J5276_RS14945	COG0802	atpase or kinase
J5276_RS14950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5276_RS14960	COG1074	ATP-dependent DNA helicase activity
J5276_RS14970	COG0285	dihydrofolate synthase activity
J5276_RS14975	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J5276_RS14980	COG0159	tryptophan synthase activity
J5276_RS14985	COG0133	tryptophan synthase activity
J5276_RS14990	COG0135	phosphoribosylanthranilate isomerase activity
J5276_RS15005	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5276_RS15030	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J5276_RS15040	COG3030	protein affecting phage T7 exclusion by the F plasmid
J5276_RS15045	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J5276_RS15055	COG0237	dephospho-CoA kinase activity
J5276_RS15060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5276_RS15065	COG0424	maF-like protein
J5276_RS15070	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J5276_RS15075	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J5276_RS15080	COG1981	membrane
J5276_RS15085	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5276_RS15090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5276_RS15095	COG0445	tRNA wobble uridine modification
J5276_RS15100	COG0357	Ribosomal RNA small subunit methyltransferase G
J5276_RS15155	COG3547	Transposase (IS116 IS110 IS902 family)
J5276_RS15205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J5276_RS15210	COG0358	DNA primase activity
J5276_RS15275	COG2814	Major facilitator Superfamily
J5276_RS15305	COG0596	Alpha beta hydrolase
J5276_RS15330	COG1764	response to oxidative stress
J5276_RS15340	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
J5276_RS15350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS15395	COG1522	sequence-specific DNA binding
J5276_RS15405	COG0071	Belongs to the small heat shock protein (HSP20) family
J5276_RS15420	COG0438	transferase activity, transferring glycosyl groups
J5276_RS15440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5276_RS15475	COG2197	response regulator
J5276_RS15480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5276_RS15485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5276_RS15490	COG4310	Domain of unknown function (DUF2172)
J5276_RS15495	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
J5276_RS15505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5276_RS15510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J5276_RS15515	COG2197	response regulator
J5276_RS15540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_RS15580	COG4178	(ABC) transporter
J5276_RS15600	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J5276_RS15610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J5276_RS15620	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J5276_RS15635	COG1177	transmembrane transport
J5276_RS15640	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_RS15645	COG3842	ATPase activity
J5276_RS15675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS15680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS15685	COG0601	transmembrane transport
J5276_RS15690	COG0747	negative chemotaxis
J5276_RS15720	COG1522	sequence-specific DNA binding
J5276_RS15735	COG0477	Major facilitator Superfamily
J5276_RS15740	COG0583	DNA-binding transcription factor activity
J5276_RS15755	COG0583	DNA-binding transcription factor activity
J5276_RS15765	COG0747	negative chemotaxis
J5276_RS15770	COG0601	transmembrane transport
J5276_RS15775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS15790	COG1278	Cold shock
J5276_RS15810	COG2198	Histidine kinase
J5276_RS15810	COG0784	Response regulator, receiver
J5276_RS15810	COG5002	protein histidine kinase activity
J5276_RS15820	COG0405	Gamma-glutamyltransferase
J5276_RS15825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS15830	COG0601	transmembrane transport
J5276_RS15835	COG0747	negative chemotaxis
J5276_RS15840	COG2186	Transcriptional regulator
J5276_RS15880	COG1595	DNA-templated transcription, initiation
J5276_RS15890	COG0395	ABC-type sugar transport system, permease component
J5276_RS15895	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_RS15905	COG3842	ATPase activity
J5276_RS15915	COG0765	amino acid transport
J5276_RS15920	COG0765	amino acid transport
J5276_RS15925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS15930	COG2186	Transcriptional regulator
J5276_RS15945	COG1063	alcohol dehydrogenase
J5276_RS15950	COG3284	Transcriptional regulator
J5276_RS15975	COG1653	transport
J5276_RS15980	COG1175	transmembrane transport
J5276_RS15985	COG0395	ABC-type sugar transport system, permease component
J5276_RS15990	COG3842	ATPase activity
J5276_RS16000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5276_RS16005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_RS16010	COG1116	anion transmembrane transporter activity
J5276_RS16015	COG0395	ABC-type sugar transport system, permease component
J5276_RS16020	COG1175	transmembrane transport
J5276_RS16050	COG1609	Transcriptional regulator
J5276_RS16065	COG1082	Xylose isomerase domain protein TIM barrel
J5276_RS16070	COG3842	ATPase activity
J5276_RS16075	COG0395	ABC-type sugar transport system, permease component
J5276_RS16080	COG1175	transmembrane transport
J5276_RS16085	COG1653	transport
J5276_RS16090	COG1309	transcriptional regulator
J5276_RS16095	COG0673	inositol 2-dehydrogenase activity
J5276_RS16110	COG0673	inositol 2-dehydrogenase activity
J5276_RS16115	COG1278	Cold shock
J5276_RS16125	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5276_RS16160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5276_RS16165	COG0577	efflux transmembrane transporter activity
J5276_RS16165	COG1136	(ABC) transporter
J5276_RS16170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_RS16190	COG2205	protein histidine kinase activity
J5276_RS16195	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
J5276_RS16210	COG3842	ATPase activity
J5276_RS16215	COG0395	ABC-type sugar transport system, permease component
J5276_RS16220	COG1175	transmembrane transport
J5276_RS16240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_RS16245	COG3618	amidohydrolase
J5276_RS16250	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_RS16255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_RS16260	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS16265	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
J5276_RS16270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_RS16275	COG2186	Transcriptional regulator
J5276_RS16290	COG0667	Aldo Keto reductase
J5276_RS16320	COG4977	sequence-specific DNA binding
J5276_RS16325	COG2223	nitrite transmembrane transporter activity
J5276_RS16330	COG0583	DNA-binding transcription factor activity
J5276_RS16335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5276_RS16345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_RS16350	COG2084	Dehydrogenase
J5276_RS16365	COG1609	Transcriptional regulator
J5276_RS16370	COG1063	alcohol dehydrogenase
J5276_RS16375	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS16385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_RS16390	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
J5276_RS16395	COG1175	transmembrane transport
J5276_RS16400	COG0395	ABC-type sugar transport system, permease component
J5276_RS16415	COG0395	ABC-type sugar transport system, permease component
J5276_RS16425	COG2182	Extracellular solute-binding protein
J5276_RS16430	COG0626	cystathionine gamma-synthase activity
J5276_RS16440	COG0803	Belongs to the bacterial solute-binding protein 9 family
J5276_RS16450	COG1121	(ABC) transporter
J5276_RS16455	COG0523	cobalamin synthesis protein
J5276_RS16470	COG0523	cobalamin synthesis protein
J5276_RS16475	COG1653	transport
J5276_RS16480	COG1175	transmembrane transport
J5276_RS16485	COG0395	ABC-type sugar transport system, permease component
J5276_RS16490	COG3842	ATPase activity
J5276_RS16500	COG3047	cAMP biosynthetic process
J5276_RS16525	COG0583	DNA-binding transcription factor activity
J5276_RS16530	COG1879	ABC-type sugar transport system periplasmic component
J5276_RS16535	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS16540	COG1129	ABC transporter
J5276_RS16545	COG5002	protein histidine kinase activity
J5276_RS16545	COG5001	Diguanylate cyclase
J5276_RS16545	COG3447	MASE1 domain protein
J5276_RS16550	COG3257	ureidoglycine aminohydrolase activity
J5276_RS16560	COG5001	Diguanylate cyclase
J5276_RS16565	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J5276_RS16575	COG0747	negative chemotaxis
J5276_RS16580	COG0601	transmembrane transport
J5276_RS16585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS16595	COG4608	Belongs to the ABC transporter superfamily
J5276_RS16600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5276_RS16610	COG0129	dihydroxy-acid dehydratase activity
J5276_RS16615	COG1879	ABC-type sugar transport system periplasmic component
J5276_RS16620	COG1129	ABC transporter
J5276_RS16625	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS16630	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS16635	COG2186	Transcriptional regulator
J5276_RS16650	COG0587	DNA-directed DNA polymerase activity
J5276_RS16680	COG0673	inositol 2-dehydrogenase activity
J5276_RS16690	COG3842	ATPase activity
J5276_RS16695	COG0395	ABC-type sugar transport system, permease component
J5276_RS16700	COG1175	transmembrane transport
J5276_RS16705	COG1653	transport
J5276_RS16715	COG0673	inositol 2-dehydrogenase activity
J5276_RS16730	COG5001	Diguanylate cyclase
J5276_RS16745	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J5276_RS16750	COG2894	cell division
J5276_RS16755	COG0850	regulation of cytokinetic process
J5276_RS16760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5276_RS16765	COG2186	Transcriptional regulator
J5276_RS16770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_RS16780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5276_RS16785	COG1063	alcohol dehydrogenase
J5276_RS16790	COG1312	Catalyzes the dehydration of D-mannonate
J5276_RS16805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_RS16810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5276_RS16810	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5276_RS16815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS16830	COG0625	glutathione transferase activity
J5276_RS16835	COG4172	Belongs to the ABC transporter superfamily
J5276_RS16840	COG1921	L-seryl-tRNASec selenium transferase activity
J5276_RS16855	COG3964	amidohydrolase
J5276_RS16865	COG0601	transmembrane transport
J5276_RS16870	COG0747	negative chemotaxis
J5276_RS16880	COG0438	transferase activity, transferring glycosyl groups
J5276_RS16925	COG4989	oxidoreductase activity
J5276_RS16935	COG2188	Transcriptional regulator
J5276_RS16940	COG3842	ATPase activity
J5276_RS16945	COG1653	transport
J5276_RS16950	COG1175	transmembrane transport
J5276_RS16955	COG0395	ABC-type sugar transport system, permease component
J5276_RS16960	COG1501	Belongs to the glycosyl hydrolase 31 family
J5276_RS16970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_RS16975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5276_RS16980	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J5276_RS16985	COG0352	thiamine-phosphate diphosphorylase activity
J5276_RS16990	COG0351	phosphomethylpyrimidine kinase
J5276_RS16995	COG1522	sequence-specific DNA binding
J5276_RS17000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5276_RS17005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS17020	COG2204	response regulator
J5276_RS17025	COG4191	Histidine kinase
J5276_RS17030	COG1301	dicarboxylic acid transport
J5276_RS17040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5276_RS17045	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS17055	COG1473	amidohydrolase
J5276_RS17075	COG1215	transferase activity, transferring glycosyl groups
J5276_RS17085	COG2942	2-epimerase
J5276_RS17110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_RS17150	COG3307	-O-antigen
J5276_RS17155	COG1596	polysaccharide export
J5276_RS17160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5276_RS17175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5276_RS17180	COG0840	transmembrane signaling receptor activity
J5276_RS17185	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS17205	COG2094	Belongs to the DNA glycosylase MPG family
J5276_RS17220	COG1609	Transcriptional regulator
J5276_RS17225	COG1653	transport
J5276_RS17240	COG3842	ATPase activity
J5276_RS17250	COG0673	inositol 2-dehydrogenase activity
J5276_RS17255	COG0602	queuosine metabolic process
J5276_RS17260	COG0720	synthase
J5276_RS17265	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5276_RS17275	COG0673	inositol 2-dehydrogenase activity
J5276_RS17290	COG0395	ABC-type sugar transport system, permease component
J5276_RS17295	COG1175	transmembrane transport
J5276_RS17320	COG0583	DNA-binding transcription factor activity
J5276_RS17325	COG0280	phosphate acetyltransferase
J5276_RS17325	COG0281	malic enzyme
J5276_RS17340	COG0765	amino acid transport
J5276_RS17345	COG1126	abc transporter atp-binding protein
J5276_RS17350	COG2079	MmgE PrpD family protein
J5276_RS17355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS17365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS17380	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5276_RS17390	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5276_RS17395	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J5276_RS17400	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS17405	COG1129	ABC transporter
J5276_RS17415	COG1473	amidohydrolase
J5276_RS17420	COG0747	negative chemotaxis
J5276_RS17430	COG4172	Belongs to the ABC transporter superfamily
J5276_RS17435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS17440	COG0601	transmembrane transport
J5276_RS17445	COG0583	DNA-binding transcription factor activity
J5276_RS17450	COG1446	asparaginase
J5276_RS17465	COG0747	negative chemotaxis
J5276_RS17485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS17490	COG0601	transmembrane transport
J5276_RS17495	COG2197	response regulator
J5276_RS17500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_RS17505	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
J5276_RS17525	COG1595	DNA-templated transcription, initiation
J5276_RS17530	COG1120	ATPase activity
J5276_RS17535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS17550	COG2226	methyltransferase
J5276_RS17560	COG1120	ATPase activity
J5276_RS17565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS17585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5276_RS17600	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS17605	COG0473	3-isopropylmalate dehydrogenase activity
J5276_RS17610	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS17615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS17645	COG0601	transmembrane transport
J5276_RS17650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS17655	COG4172	Belongs to the ABC transporter superfamily
J5276_RS17660	COG1522	sequence-specific DNA binding
J5276_RS17675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS17690	COG1473	amidohydrolase
J5276_RS17695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS17700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS17705	COG1959	2 iron, 2 sulfur cluster binding
J5276_RS17715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5276_RS17720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS17740	COG1960	acyl-CoA dehydrogenase activity
J5276_RS17750	COG0747	negative chemotaxis
J5276_RS17765	COG0444	Belongs to the ABC transporter superfamily
J5276_RS17775	COG0667	Aldo Keto reductase
J5276_RS17785	COG0583	DNA-binding transcription factor activity
J5276_RS17790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS17805	COG0747	negative chemotaxis
J5276_RS17810	COG1473	amidohydrolase
J5276_RS17815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS17830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS17835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS17855	COG4608	Belongs to the ABC transporter superfamily
J5276_RS17860	COG0444	Belongs to the ABC transporter superfamily
J5276_RS17870	COG0601	transmembrane transport
J5276_RS17880	COG2186	Transcriptional regulator
J5276_RS17895	COG0300	oxidoreductase activity
J5276_RS17905	COG3453	Protein conserved in bacteria
J5276_RS17905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5276_RS17910	COG0640	Transcriptional regulator
J5276_RS17920	COG2391	methyltransferase activity
J5276_RS17925	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J5276_RS17935	COG0022	dehydrogenase e1 component
J5276_RS17945	COG1960	acyl-CoA dehydrogenase activity
J5276_RS17950	COG0183	Belongs to the thiolase family
J5276_RS17960	COG1960	acyl-CoA dehydrogenase activity
J5276_RS17965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J5276_RS17980	COG1024	Enoyl-CoA hydratase
J5276_RS17985	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5276_RS17990	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5276_RS17995	COG4952	isomerase
J5276_RS18000	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS18000	COG3347	Dehydrogenase
J5276_RS18005	COG1349	DNA-binding transcription factor activity
J5276_RS18015	COG1129	ABC transporter
J5276_RS18020	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS18025	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS18030	COG3254	rhamnose metabolic process
J5276_RS18045	COG2264	protein methyltransferase activity
J5276_RS18050	COG5001	Diguanylate cyclase
J5276_RS18065	COG4335	DNA alkylation repair
J5276_RS18070	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5276_RS18075	COG4208	sulfate ABC transporter
J5276_RS18085	COG4150	thiosulfate binding
J5276_RS18090	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J5276_RS18105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5276_RS18115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5276_RS18125	COG1040	competence protein
J5276_RS18130	COG2226	methyltransferase
J5276_RS18145	COG0494	nUDIX hydrolase
J5276_RS18155	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J5276_RS18160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5276_RS18165	COG0653	protein targeting
J5276_RS18235	COG2244	polysaccharide biosynthetic process
J5276_RS18250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5276_RS18280	COG0438	transferase activity, transferring glycosyl groups
J5276_RS18285	COG0438	transferase activity, transferring glycosyl groups
J5276_RS18300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5276_RS18305	COG2273	Hydrolase Family 16
J5276_RS18305	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
J5276_RS18320	COG3842	ATPase activity
J5276_RS18325	COG3833	ABC-type maltose transport systems, permease component
J5276_RS18380	COG1396	sequence-specific DNA binding
J5276_RS18390	COG1129	ABC transporter
J5276_RS18395	COG4214	carbohydrate transport
J5276_RS18400	COG4213	ABC transporter substrate-binding protein
J5276_RS18415	COG0346	lactoylglutathione lyase activity
J5276_RS18420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5276_RS18420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5276_RS18425	COG4770	biotin carboxylase activity
J5276_RS18435	COG0625	glutathione transferase activity
J5276_RS18440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J5276_RS18445	COG1396	sequence-specific DNA binding
J5276_RS18445	COG3800	Transcriptional regulator
J5276_RS18455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5276_RS18465	COG0300	oxidoreductase activity
J5276_RS18475	COG2096	Adenosyltransferase
J5276_RS18485	COG2086	electron transfer activity
J5276_RS18495	COG1250	3-hydroxyacyl-CoA dehydrogenase
J5276_RS18500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5276_RS18505	COG0165	Argininosuccinate lyase
J5276_RS18540	COG2884	Cell division ATP-binding protein ftsE
J5276_RS18560	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
J5276_RS18575	COG0287	Prephenate dehydrogenase
J5276_RS18580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5276_RS18585	COG2226	methyltransferase
J5276_RS18590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5276_RS18605	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5276_RS18610	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J5276_RS18645	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5276_RS18650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5276_RS18660	COG4974	Belongs to the 'phage' integrase family
J5276_RS18665	COG0825	malonyl-CoA metabolic process
J5276_RS18670	COG3034	peptidoglycan biosynthetic process
J5276_RS18675	COG0425	Belongs to the sulfur carrier protein TusA family
J5276_RS18680	COG0523	cobalamin synthesis protein
J5276_RS18685	COG1686	Belongs to the peptidase S11 family
J5276_RS18690	COG1473	amidohydrolase
J5276_RS18700	COG4953	penicillin-binding protein 1C
J5276_RS18705	COG2373	Large extracellular alpha-helical protein
J5276_RS18710	COG2835	tetraacyldisaccharide 4'-kinase activity
J5276_RS18720	COG3118	belongs to the thioredoxin family
J5276_RS18775	COG2801	Transposase and inactivated derivatives
J5276_RS18875	COG4373	Mu-like prophage FluMu protein gp28
J5276_RS18880	COG4383	Mu-like prophage protein gp29
J5276_RS18905	COG4397	Mu-like prophage major head subunit gpT
J5276_RS18975	COG3299	homolog of phage Mu protein gp47
J5276_RS19015	COG0482	sulfurtransferase activity
J5276_RS19030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5276_RS19045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5276_RS19050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5276_RS19055	COG0037	tRNA processing
J5276_RS19065	COG2885	chlorophyll binding
J5276_RS19070	COG0823	Involved in the tonB-independent uptake of proteins
J5276_RS19090	COG0824	Thioesterase
J5276_RS19100	COG0494	nUDIX hydrolase
J5276_RS19115	COG2255	four-way junction helicase activity
J5276_RS19120	COG0632	four-way junction helicase activity
J5276_RS19125	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5276_RS19130	COG2972	Histidine kinase
J5276_RS19130	COG0840	transmembrane signaling receptor activity
J5276_RS19135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS19140	COG0217	transcriptional regulatory protein
J5276_RS19155	COG1692	metallophosphoesterase
J5276_RS19165	COG1253	flavin adenine dinucleotide binding
J5276_RS19205	COG0126	phosphoglycerate kinase activity
J5276_RS19210	COG3588	fructose-bisphosphate aldolase
J5276_RS19235	COG0254	rRNA binding
J5276_RS19240	COG1132	(ABC) transporter
J5276_RS19260	COG0483	inositol monophosphate 1-phosphatase activity
J5276_RS19290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J5276_RS19295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J5276_RS19300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5276_RS19305	COG0457	Tetratricopeptide repeat
J5276_RS19310	COG3750	Belongs to the UPF0335 family
J5276_RS19330	COG0469	pyruvate kinase activity
J5276_RS19335	COG3108	Peptidase M15
J5276_RS19340	COG2204	response regulator
J5276_RS19345	COG1164	Oligoendopeptidase f
J5276_RS19350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J5276_RS19360	COG5310	Homospermidine synthase
J5276_RS19370	COG0737	Belongs to the 5'-nucleotidase family
J5276_RS19375	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J5276_RS19380	COG0330	HflC and HflK could
J5276_RS19405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J5276_RS19410	COG2951	lytic endotransglycosylase activity
J5276_RS19425	COG2205	protein histidine kinase activity
J5276_RS19440	COG0069	glutamate synthase activity
J5276_RS19440	COG0070	glutamate synthase
J5276_RS19440	COG0067	glutamate synthase
J5276_RS19455	COG2205	protein histidine kinase activity
J5276_RS19460	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
J5276_RS19465	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J5276_RS19475	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5276_RS19490	COG0252	asparaginase activity
J5276_RS19500	COG1027	Aspartate ammonia-lyase
J5276_RS19505	COG2186	Transcriptional regulator
J5276_RS19530	COG3239	Fatty acid desaturase
J5276_RS19550	COG0583	DNA-binding transcription factor activity
J5276_RS19570	COG3842	ATPase activity
J5276_RS19575	COG1177	transmembrane transport
J5276_RS19595	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS19600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS19610	COG2267	carboxylic ester hydrolase activity
J5276_RS19625	COG1126	abc transporter atp-binding protein
J5276_RS19630	COG0765	amino acid transport
J5276_RS19650	COG0174	glutamine synthetase
J5276_RS19655	COG0069	glutamate synthase activity
J5276_RS19660	COG2218	PFAM glutamate synthase alpha subunit domain protein
J5276_RS19665	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J5276_RS19685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_RS19695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS19700	COG0601	transmembrane transport
J5276_RS19705	COG0747	negative chemotaxis
J5276_RS19715	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5276_RS19720	COG1454	alcohol dehydrogenase
J5276_RS19765	COG2307	Protein conserved in bacteria
J5276_RS19765	COG2308	Evidence 4 Homologs of previously reported genes of
J5276_RS19780	COG0488	(ABC) transporter
J5276_RS19785	COG1304	FMN binding
J5276_RS19790	COG1846	Transcriptional regulator
J5276_RS19795	COG0840	transmembrane signaling receptor activity
J5276_RS19800	COG1070	Carbohydrate kinase
J5276_RS19805	COG1830	Aldolase
J5276_RS19810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J5276_RS19815	COG0667	Aldo Keto reductase
J5276_RS19825	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS19830	COG1129	ABC transporter
J5276_RS19835	COG1879	ABC-type sugar transport system periplasmic component
J5276_RS19865	COG0071	Belongs to the small heat shock protein (HSP20) family
J5276_RS19880	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J5276_RS19895	COG0395	ABC-type sugar transport system, permease component
J5276_RS19905	COG3842	ATPase activity
J5276_RS19910	COG3842	ATPase activity
J5276_RS19925	COG1648	precorrin-2 dehydrogenase activity
J5276_RS19925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5276_RS19930	COG0243	molybdopterin cofactor binding
J5276_RS19940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J5276_RS19945	COG1116	anion transmembrane transporter activity
J5276_RS19950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_RS19955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5276_RS19965	COG3707	response regulator
J5276_RS19970	COG1802	Transcriptional regulator
J5276_RS19975	COG1914	H( )-stimulated, divalent metal cation uptake system
J5276_RS19980	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J5276_RS19985	COG4336	lyase activity
J5276_RS19990	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J5276_RS19995	COG4770	biotin carboxylase activity
J5276_RS20000	COG0366	Alpha amylase catalytic
J5276_RS20010	COG4771	TonB-dependent receptor
J5276_RS20015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5276_RS20035	COG1414	Transcriptional regulator
J5276_RS20040	COG1475	DNA binding
J5276_RS20045	COG1192	Involved in chromosome partitioning
J5276_RS20075	COG0596	Alpha beta hydrolase
J5276_RS20080	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
J5276_RS20090	COG2986	histidine ammonia-lyase
J5276_RS20095	COG1228	amidohydrolase
J5276_RS20100	COG0402	S-adenosylhomocysteine deaminase activity
J5276_RS20140	COG0511	ligase activity, forming carbon-carbon bonds
J5276_RS20145	COG0439	Biotin carboxylase
J5276_RS20160	COG1984	allophanate hydrolase subunit 2
J5276_RS20165	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J5276_RS20170	COG0436	Aminotransferase
J5276_RS20180	COG4221	oxidoreductase activity
J5276_RS20185	COG0765	amino acid transport
J5276_RS20190	COG0765	amino acid transport
J5276_RS20195	COG1126	abc transporter atp-binding protein
J5276_RS20200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS20205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J5276_RS20210	COG0010	Belongs to the arginase family
J5276_RS20215	COG1126	abc transporter atp-binding protein
J5276_RS20225	COG0765	amino acid transport
J5276_RS20240	COG0640	Transcriptional regulator
J5276_RS20250	COG0431	NADPH-dependent FMN reductase
J5276_RS20260	COG0798	PFAM Bile acid sodium symporter
J5276_RS20270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J5276_RS20275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_RS20285	COG3842	ATPase activity
J5276_RS20290	COG0395	ABC-type sugar transport system, permease component
J5276_RS20295	COG1175	transmembrane transport
J5276_RS20305	COG0673	inositol 2-dehydrogenase activity
J5276_RS20310	COG0673	inositol 2-dehydrogenase activity
J5276_RS20350	COG0583	DNA-binding transcription factor activity
J5276_RS20355	COG0477	Major facilitator Superfamily
J5276_RS20365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS20375	COG4172	Belongs to the ABC transporter superfamily
J5276_RS20380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS20385	COG0601	transmembrane transport
J5276_RS20400	COG0277	FAD linked oxidase domain protein
J5276_RS20420	COG2205	protein histidine kinase activity
J5276_RS20425	COG0745	RESPONSE REGULATOR receiver
J5276_RS20430	COG0671	phosphoesterase, PA-phosphatase related
J5276_RS20480	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5276_RS20490	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5276_RS20495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5276_RS20500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5276_RS20515	COG0010	Belongs to the arginase family
J5276_RS20525	COG0697	spore germination
J5276_RS20530	COG0673	inositol 2-dehydrogenase activity
J5276_RS20550	COG0477	Major facilitator Superfamily
J5276_RS20555	COG0642	Histidine kinase
J5276_RS20565	COG2194	sulfuric ester hydrolase activity
J5276_RS20575	COG0583	DNA-binding transcription factor activity
J5276_RS20580	COG4774	siderophore transport
J5276_RS20595	COG1120	ATPase activity
J5276_RS20610	COG2137	regulation of response to DNA damage stimulus
J5276_RS20615	COG3386	PFAM SMP-30 Gluconolaconase
J5276_RS20625	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS20630	COG1129	ABC transporter
J5276_RS20635	COG1879	ABC-type sugar transport system periplasmic component
J5276_RS20640	COG4585	Histidine kinase
J5276_RS20645	COG2197	response regulator
J5276_RS20655	COG2133	pyrroloquinoline quinone binding
J5276_RS20665	COG0500	methyltransferase
J5276_RS20670	COG0564	pseudouridine synthase activity
J5276_RS20685	COG0517	IMP dehydrogenase activity
J5276_RS20685	COG4175	Glycine betaine
J5276_RS20690	COG4176	ABC-type proline glycine betaine transport system permease component
J5276_RS20700	COG0784	Response regulator, receiver
J5276_RS20700	COG4191	Histidine kinase
J5276_RS20710	COG0489	protein tyrosine kinase activity
J5276_RS20710	COG3206	protein involved in exopolysaccharide biosynthesis
J5276_RS20715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J5276_RS20720	COG1215	transferase activity, transferring glycosyl groups
J5276_RS20725	COG1215	transferase activity, transferring glycosyl groups
J5276_RS20730	COG1215	transferase activity, transferring glycosyl groups
J5276_RS20735	COG0438	transferase activity, transferring glycosyl groups
J5276_RS20740	COG2273	Hydrolase Family 16
J5276_RS20745	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5276_RS20750	COG2244	polysaccharide biosynthetic process
J5276_RS20755	COG0463	Glycosyl transferase, family 2
J5276_RS20760	COG2327	Polysaccharide pyruvyl transferase
J5276_RS20765	COG1215	transferase activity, transferring glycosyl groups
J5276_RS20785	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5276_RS20790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS20805	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5276_RS20805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J5276_RS20830	COG1523	belongs to the glycosyl hydrolase 13 family
J5276_RS20835	COG0033	Phosphoglucomutase
J5276_RS20840	COG0297	glycogen (starch) synthase activity
J5276_RS20845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J5276_RS20850	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J5276_RS20855	COG0058	SHG alpha-glucan phosphorylase activity
J5276_RS20865	COG1794	racemase activity, acting on amino acids and derivatives
J5276_RS20870	COG1522	sequence-specific DNA binding
J5276_RS20880	COG2084	Dehydrogenase
J5276_RS20885	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS20890	COG1063	alcohol dehydrogenase
J5276_RS20900	COG4988	ABC transporter
J5276_RS20905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J5276_RS20915	COG1294	oxidase, subunit
J5276_RS20945	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J5276_RS20950	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5276_RS20980	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5276_RS20985	COG0539	negative regulation of cytoplasmic translation
J5276_RS21015	COG4221	oxidoreductase activity
J5276_RS21020	COG0006	proline dipeptidase activity
J5276_RS21025	COG0747	negative chemotaxis
J5276_RS21030	COG0601	transmembrane transport
J5276_RS21035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS21040	COG0444	Belongs to the ABC transporter superfamily
J5276_RS21045	COG4608	Belongs to the ABC transporter superfamily
J5276_RS21060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS21075	COG0411	ABC transporter
J5276_RS21085	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5276_RS21105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J5276_RS21110	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS21130	COG4993	Dehydrogenase
J5276_RS21135	COG3685	Protein conserved in bacteria
J5276_RS21145	COG0693	protein deglycase activity
J5276_RS21170	COG0189	ligase activity
J5276_RS21175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_RS21180	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J5276_RS21190	COG0435	Glutathione S-transferase
J5276_RS21195	COG0583	DNA-binding transcription factor activity
J5276_RS21200	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS21205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5276_RS21210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_RS21215	COG1116	anion transmembrane transporter activity
J5276_RS21225	COG1522	sequence-specific DNA binding
J5276_RS21240	COG0784	Response regulator, receiver
J5276_RS21260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5276_RS21280	COG0019	diaminopimelate decarboxylase activity
J5276_RS21295	COG0527	aspartate kinase activity
J5276_RS21305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5276_RS21310	COG2890	protein-(glutamine-N5) methyltransferase activity
J5276_RS21320	COG0542	response to heat
J5276_RS21325	COG0739	heme binding
J5276_RS21325	COG0741	lytic transglycosylase activity
J5276_RS21325	COG1196	nuclear chromosome segregation
J5276_RS21360	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J5276_RS21365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5276_RS21380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5276_RS21385	COG1309	transcriptional regulator
J5276_RS21390	COG4221	oxidoreductase activity
J5276_RS21395	COG1902	pentaerythritol trinitrate reductase activity
J5276_RS21400	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS21405	COG0604	alcohol dehydrogenase
J5276_RS21415	COG0243	molybdopterin cofactor binding
J5276_RS21420	COG2814	Major facilitator Superfamily
J5276_RS21430	COG0492	ferredoxin-NADP+ reductase activity
J5276_RS21440	COG4566	intracellular signal transduction
J5276_RS21445	COG4566	intracellular signal transduction
J5276_RS21455	COG2140	Oxalate decarboxylase
J5276_RS21460	COG0783	Belongs to the Dps family
J5276_RS21470	COG0583	DNA-binding transcription factor activity
J5276_RS21480	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS21485	COG1846	Transcriptional regulator
J5276_RS21500	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
J5276_RS21505	COG0583	DNA-binding transcription factor activity
J5276_RS21510	COG0346	lactoylglutathione lyase activity
J5276_RS21530	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J5276_RS21555	COG2080	2 iron, 2 sulfur cluster binding
J5276_RS21560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J5276_RS21565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J5276_RS21570	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J5276_RS21575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5276_RS21595	COG1278	Cold shock
J5276_RS21625	COG2986	histidine ammonia-lyase
J5276_RS21645	COG4172	Belongs to the ABC transporter superfamily
J5276_RS21650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS21655	COG0601	transmembrane transport
J5276_RS21660	COG4166	transmembrane transport
J5276_RS21665	COG0840	transmembrane signaling receptor activity
J5276_RS21675	COG5001	Diguanylate cyclase
J5276_RS21675	COG3300	MHYT domain
J5276_RS21695	COG1609	Transcriptional regulator
J5276_RS21710	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS21715	COG1735	metal-dependent hydrolase with the TIM-barrel fold
J5276_RS21740	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
J5276_RS21745	COG1049	propionate catabolic process, 2-methylcitrate cycle
J5276_RS21755	COG0367	asparagine synthase
J5276_RS21765	COG0318	PFAM AMP-dependent synthetase and ligase
J5276_RS21770	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J5276_RS21790	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5276_RS21790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J5276_RS21795	COG4311	Sarcosine oxidase, delta subunit
J5276_RS21800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS21805	COG4977	sequence-specific DNA binding
J5276_RS21810	COG1129	ABC transporter
J5276_RS21820	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS21835	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS21840	COG0246	Mannitol dehydrogenase
J5276_RS21845	COG1312	Catalyzes the dehydration of D-mannonate
J5276_RS21865	COG1309	transcriptional regulator
J5276_RS21870	COG1063	alcohol dehydrogenase
J5276_RS21880	COG1879	ABC-type sugar transport system periplasmic component
J5276_RS21890	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS21910	COG0477	Major facilitator Superfamily
J5276_RS21920	COG0483	inositol monophosphate 1-phosphatase activity
J5276_RS21945	COG1178	ABC-type Fe3 transport system permease component
J5276_RS21950	COG3842	ATPase activity
J5276_RS21980	COG1253	flavin adenine dinucleotide binding
J5276_RS21995	COG3842	ATPase activity
J5276_RS22000	COG0395	ABC-type sugar transport system, permease component
J5276_RS22005	COG1175	transmembrane transport
J5276_RS22010	COG1653	transport
J5276_RS22020	COG0673	inositol 2-dehydrogenase activity
J5276_RS22025	COG1609	Transcriptional regulator
J5276_RS22040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS22060	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5276_RS22070	COG0668	transmembrane transport
J5276_RS22100	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS22105	COG3433	isochorismatase activity
J5276_RS22105	COG1535	isochorismatase
J5276_RS22110	COG1021	2,3-dihydroxybenzoate-AMP ligase
J5276_RS22115	COG1169	isochorismate synthase
J5276_RS22125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J5276_RS22125	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J5276_RS22130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J5276_RS22140	COG2375	cellular response to nickel ion
J5276_RS22150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS22155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS22160	COG1120	ATPase activity
J5276_RS22165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS22175	COG1629	transport
J5276_RS22175	COG4774	siderophore transport
J5276_RS22180	COG1960	acyl-CoA dehydrogenase activity
J5276_RS22185	COG0583	DNA-binding transcription factor activity
J5276_RS22190	COG1609	Transcriptional regulator
J5276_RS22200	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_RS22220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J5276_RS22230	COG1473	amidohydrolase
J5276_RS22245	COG0747	negative chemotaxis
J5276_RS22250	COG0601	transmembrane transport
J5276_RS22255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS22260	COG0444	Belongs to the ABC transporter superfamily
J5276_RS22265	COG4608	Belongs to the ABC transporter superfamily
J5276_RS22270	COG0583	DNA-binding transcription factor activity
J5276_RS22275	COG0747	negative chemotaxis
J5276_RS22285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS22295	COG0693	protein deglycase activity
J5276_RS22305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS22310	COG0601	transmembrane transport
J5276_RS22320	COG1473	amidohydrolase
J5276_RS22325	COG4172	Belongs to the ABC transporter superfamily
J5276_RS22330	COG2390	Transcriptional regulator
J5276_RS22340	COG1175	transmembrane transport
J5276_RS22345	COG0395	ABC-type sugar transport system, permease component
J5276_RS22390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5276_RS22400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J5276_RS22405	COG1414	Transcriptional regulator
J5276_RS22410	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS22415	COG5487	UPF0391 membrane protein
J5276_RS22420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5276_RS22425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5276_RS22430	COG1121	(ABC) transporter
J5276_RS22435	COG0803	Belongs to the bacterial solute-binding protein 9 family
J5276_RS22445	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J5276_RS22450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5276_RS22455	COG0471	metal ion transport
J5276_RS22455	COG3273	potassium ion transport
J5276_RS22460	COG1253	flavin adenine dinucleotide binding
J5276_RS22465	COG1309	transcriptional regulator
J5276_RS22480	COG1609	Transcriptional regulator
J5276_RS22485	COG1070	Carbohydrate kinase
J5276_RS22490	COG2115	Belongs to the xylose isomerase family
J5276_RS22500	COG0778	Nitroreductase
J5276_RS22505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J5276_RS22510	COG2011	ABC-type metal ion transport system permease component
J5276_RS22520	COG3300	MHYT domain
J5276_RS22520	COG5001	Diguanylate cyclase
J5276_RS22525	COG1054	Belongs to the UPF0176 family
J5276_RS22535	COG2954	triphosphatase activity
J5276_RS22540	COG0800	Aldolase
J5276_RS22560	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
J5276_RS22595	COG0523	cobalamin synthesis protein
J5276_RS22605	COG1846	Transcriptional regulator
J5276_RS22610	COG1609	Transcriptional regulator
J5276_RS22615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5276_RS22620	COG0673	inositol 2-dehydrogenase activity
J5276_RS22625	COG3718	enzyme involved in inositol metabolism
J5276_RS22635	COG3962	Belongs to the TPP enzyme family
J5276_RS22640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_RS22650	COG3842	ATPase activity
J5276_RS22670	COG0683	leucine binding
J5276_RS22685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS22695	COG0747	negative chemotaxis
J5276_RS22710	COG1082	Xylose isomerase domain protein TIM barrel
J5276_RS22710	COG3185	4-Hydroxyphenylpyruvate dioxygenase
J5276_RS22720	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J5276_RS22725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5276_RS22730	COG1126	abc transporter atp-binding protein
J5276_RS22735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS22740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS22745	COG0765	amino acid transport
J5276_RS22750	COG0765	amino acid transport
J5276_RS22760	COG3485	protocatechuate 3,4-dioxygenase
J5276_RS22765	COG3485	protocatechuate 3,4-dioxygenase
J5276_RS22770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J5276_RS22780	COG0583	DNA-binding transcription factor activity
J5276_RS22795	COG1414	Transcriptional regulator
J5276_RS22805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J5276_RS22810	COG0183	Belongs to the thiolase family
J5276_RS22815	COG1609	Transcriptional regulator
J5276_RS22825	COG1082	Xylose isomerase domain protein TIM barrel
J5276_RS22830	COG0673	inositol 2-dehydrogenase activity
J5276_RS22840	COG1609	Transcriptional regulator
J5276_RS22845	COG0395	ABC-type sugar transport system, permease component
J5276_RS22850	COG1175	transmembrane transport
J5276_RS22855	COG3842	ATPase activity
J5276_RS22865	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
J5276_RS22895	COG3842	ATPase activity
J5276_RS22900	COG4149	molybdate abc transporter
J5276_RS22910	COG0584	glycerophosphoryl diester phosphodiesterase
J5276_RS22915	COG0483	inositol monophosphate 1-phosphatase activity
J5276_RS22930	COG3842	ATPase activity
J5276_RS22935	COG1177	transmembrane transport
J5276_RS22955	COG0385	Bile acid
J5276_RS22965	COG1132	(ABC) transporter
J5276_RS22995	COG1215	transferase activity, transferring glycosyl groups
J5276_RS23005	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J5276_RS23010	COG1091	dTDP-4-dehydrorhamnose reductase activity
J5276_RS23015	COG1088	dTDP-glucose 4,6-dehydratase activity
J5276_RS23020	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
J5276_RS23035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS23040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS23045	COG1120	ATPase activity
J5276_RS23050	COG4774	siderophore transport
J5276_RS23055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5276_RS23070	COG1609	Transcriptional regulator
J5276_RS23075	COG1233	COG1233 Phytoene dehydrogenase and related
J5276_RS23090	COG0395	ABC-type sugar transport system, permease component
J5276_RS23095	COG3842	ATPase activity
J5276_RS23100	COG4608	Belongs to the ABC transporter superfamily
J5276_RS23105	COG0444	Belongs to the ABC transporter superfamily
J5276_RS23110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS23115	COG0601	transmembrane transport
J5276_RS23120	COG2186	Transcriptional regulator
J5276_RS23130	COG0747	negative chemotaxis
J5276_RS23140	COG5001	Diguanylate cyclase
J5276_RS23140	COG3300	MHYT domain
J5276_RS23145	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS23155	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
J5276_RS23165	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
J5276_RS23170	COG0306	phosphate transporter
J5276_RS23175	COG1392	Phosphate transport regulator
J5276_RS23195	COG0745	RESPONSE REGULATOR receiver
J5276_RS23200	COG5002	protein histidine kinase activity
J5276_RS23215	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
J5276_RS23230	COG4774	siderophore transport
J5276_RS23240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS23245	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS23250	COG1120	ATPase activity
J5276_RS23255	COG1733	regulation of RNA biosynthetic process
J5276_RS23280	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS23285	COG0583	DNA-binding transcription factor activity
J5276_RS23295	COG3119	arylsulfatase activity
J5276_RS23300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_RS23305	COG3842	ATPase activity
J5276_RS23310	COG0165	Argininosuccinate lyase
J5276_RS23315	COG0395	ABC-type sugar transport system, permease component
J5276_RS23320	COG1175	transmembrane transport
J5276_RS23325	COG2182	Extracellular solute-binding protein
J5276_RS23330	COG1940	carbohydrate kinase activity
J5276_RS23355	COG1486	melibiose metabolic process
J5276_RS23360	COG0747	negative chemotaxis
J5276_RS23365	COG0601	transmembrane transport
J5276_RS23370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS23375	COG4172	Belongs to the ABC transporter superfamily
J5276_RS23380	COG1486	melibiose metabolic process
J5276_RS23385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_RS23390	COG1129	ABC transporter
J5276_RS23390	COG0842	Transport permease protein
J5276_RS23395	COG0842	Transport permease protein
J5276_RS23410	COG0784	Response regulator, receiver
J5276_RS23415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J5276_RS23425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_RS23430	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J5276_RS23445	COG0765	amino acid transport
J5276_RS23455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS23465	COG3938	Belongs to the proline racemase family
J5276_RS23480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS23485	COG0765	amino acid transport
J5276_RS23490	COG0765	amino acid transport
J5276_RS23500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5276_RS23515	COG0402	S-adenosylhomocysteine deaminase activity
J5276_RS23525	COG0601	transmembrane transport
J5276_RS23530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS23540	COG0402	S-adenosylhomocysteine deaminase activity
J5276_RS23545	COG0444	Belongs to the ABC transporter superfamily
J5276_RS23550	COG4608	Belongs to the ABC transporter superfamily
J5276_RS23555	COG1802	Transcriptional regulator
J5276_RS23560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5276_RS23585	COG3383	formate dehydrogenase (NAD+) activity
J5276_RS23595	COG2223	nitrite transmembrane transporter activity
J5276_RS23600	COG0456	acetyltransferase
J5276_RS23630	COG3237	CsbD-like
J5276_RS23635	COG2197	response regulator
J5276_RS23640	COG3181	Tripartite tricarboxylate transporter family receptor
J5276_RS23650	COG5265	(ABC) transporter
J5276_RS23655	COG0640	Transcriptional regulator
J5276_RS23670	COG0753	catalase activity
J5276_RS23710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J5276_RS23730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J5276_RS23735	COG5001	Diguanylate cyclase
J5276_RS23735	COG3706	GGDEF domain
J5276_RS23735	COG4251	negative regulation of phosphorylation
J5276_RS23735	COG2203	Gaf domain
J5276_RS23745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5276_RS23750	COG3046	protein related to deoxyribodipyrimidine photolyase
J5276_RS23800	COG1216	Glycosyl transferase, family 2
J5276_RS23800	COG0438	transferase activity, transferring glycosyl groups
J5276_RS23820	COG0156	8-amino-7-oxononanoate synthase activity
J5276_RS23825	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
J5276_RS23830	COG1368	sulfuric ester hydrolase activity
J5276_RS23960	COG1595	DNA-templated transcription, initiation
J5276_RS23970	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS23975	COG1309	transcriptional regulator
J5276_RS23995	COG1126	abc transporter atp-binding protein
J5276_RS24000	COG0765	amino acid transport
J5276_RS24005	COG0765	amino acid transport
J5276_RS24010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS24015	COG3608	succinylglutamate desuccinylase aspartoacylase
J5276_RS24020	COG0006	proline dipeptidase activity
J5276_RS24025	COG2423	ornithine cyclodeaminase activity
J5276_RS24030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5276_RS24035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5276_RS24040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5276_RS24050	COG1522	sequence-specific DNA binding
J5276_RS24270	COG4106	trans-aconitate 2-methyltransferase activity
J5276_RS24290	COG2814	Major facilitator Superfamily
J5276_RS24295	COG0583	DNA-binding transcription factor activity
J5276_RS24310	COG0747	negative chemotaxis
J5276_RS24315	COG0601	transmembrane transport
J5276_RS24320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS24325	COG4172	Belongs to the ABC transporter superfamily
J5276_RS24340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J5276_RS24380	COG0406	alpha-ribazole phosphatase activity
J5276_RS24485	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS24495	COG2211	Major facilitator Superfamily
J5276_RS24510	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS24515	COG1129	ABC transporter
J5276_RS24520	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS24525	COG1053	succinate dehydrogenase
J5276_RS24555	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5276_RS24560	COG0625	glutathione transferase activity
J5276_RS24585	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS24590	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS24595	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS24600	COG1129	ABC transporter
J5276_RS24675	COG1802	Transcriptional regulator
J5276_RS24680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_RS24685	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS24700	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J5276_RS24710	COG0517	IMP dehydrogenase activity
J5276_RS24710	COG4175	Glycine betaine
J5276_RS24715	COG4176	ABC-type proline glycine betaine transport system permease component
J5276_RS24720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J5276_RS24730	COG1902	pentaerythritol trinitrate reductase activity
J5276_RS24730	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5276_RS24740	COG2086	electron transfer activity
J5276_RS24765	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J5276_RS24770	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
J5276_RS24775	COG3791	Glutathione-dependent formaldehyde-activating
J5276_RS24780	COG0006	proline dipeptidase activity
J5276_RS24785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J5276_RS24820	COG1802	Transcriptional regulator
J5276_RS24825	COG0747	negative chemotaxis
J5276_RS24830	COG0601	transmembrane transport
J5276_RS24835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS24845	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_RS24850	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_RS24855	COG1609	Transcriptional regulator
J5276_RS24860	COG3250	beta-galactosidase activity
J5276_RS24870	COG1175	transmembrane transport
J5276_RS24875	COG0395	ABC-type sugar transport system, permease component
J5276_RS24895	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5276_RS24920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5276_RS24925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_RS24940	COG0596	Alpha beta hydrolase
J5276_RS24965	COG1120	ATPase activity
J5276_RS24970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J5276_RS24985	COG0019	diaminopimelate decarboxylase activity
J5276_RS24995	COG4264	IucA IucC family
J5276_RS25000	COG4264	IucA IucC family
J5276_RS25015	COG2423	ornithine cyclodeaminase activity
J5276_RS25020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J5276_RS25045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5276_RS25060	COG4598	ABC transporter
J5276_RS25110	COG1192	Involved in chromosome partitioning
J5276_RS25180	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
J5276_RS25185	COG2948	multi-organism process
J5276_RS25215	COG0741	lytic transglycosylase activity
J5276_RS25215	COG0739	heme binding
J5276_RS25215	COG1196	nuclear chromosome segregation
J5276_RS25220	COG3451	type IV secretory pathway VirB4
J5276_RS25260	COG3831	ATPase activity
J5276_RS25270	COG0776	regulation of translation
J5276_RS25345	COG1414	Transcriptional regulator
J5276_RS25350	COG1475	DNA binding
J5276_RS25355	COG1192	Involved in chromosome partitioning
J5276_RS25415	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J5276_RS25430	COG0464	growth
J5276_RS25455	COG0778	Nitroreductase
J5276_RS25460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS25465	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
J5276_RS25480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5276_RS25490	COG0583	DNA-binding transcription factor activity
J5276_RS25500	COG0235	Class ii aldolase
J5276_RS25505	COG0583	DNA-binding transcription factor activity
J5276_RS25530	COG1505	serine-type exopeptidase activity
J5276_RS25550	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS25555	COG1733	regulation of RNA biosynthetic process
J5276_RS25565	COG0477	Major facilitator Superfamily
J5276_RS25570	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS25575	COG1794	racemase activity, acting on amino acids and derivatives
J5276_RS25585	COG0300	oxidoreductase activity
J5276_RS25600	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
J5276_RS25605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J5276_RS25615	COG0287	Prephenate dehydrogenase
J5276_RS25615	COG1605	Chorismate mutase
J5276_RS25620	COG0583	DNA-binding transcription factor activity
J5276_RS25625	COG0300	oxidoreductase activity
J5276_RS25640	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_RS25650	COG0251	oxidation-reduction process
J5276_RS25670	COG0656	L-ascorbic acid biosynthetic process
J5276_RS25685	COG0583	DNA-binding transcription factor activity
J5276_RS25700	COG1473	amidohydrolase
J5276_RS25710	COG1522	sequence-specific DNA binding
J5276_RS25735	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS25740	COG2085	NADP oxidoreductase coenzyme F420-dependent
J5276_RS25750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS25755	COG1309	transcriptional regulator
J5276_RS25765	COG0583	DNA-binding transcription factor activity
J5276_RS25785	COG0473	3-isopropylmalate dehydrogenase activity
J5276_RS25790	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_RS25800	COG4221	oxidoreductase activity
J5276_RS25840	COG2186	Transcriptional regulator
J5276_RS25850	COG0765	amino acid transport
J5276_RS25860	COG3842	ATPase activity
J5276_RS25875	COG1177	transmembrane transport
J5276_RS25885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5276_RS25890	COG3257	ureidoglycine aminohydrolase activity
J5276_RS25910	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS25945	COG4221	oxidoreductase activity
J5276_RS25960	COG0459	protein refolding
J5276_RS25965	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5276_RS25970	COG5425	PFAM Usg family protein
J5276_RS25980	COG0071	Belongs to the small heat shock protein (HSP20) family
J5276_RS26000	COG0745	RESPONSE REGULATOR receiver
J5276_RS26005	COG2202	Pas domain
J5276_RS26005	COG3920	Histidine kinase
J5276_RS26010	COG0784	Response regulator, receiver
J5276_RS26010	COG4191	Histidine kinase
J5276_RS26055	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS26060	COG0668	transmembrane transport
J5276_RS26105	COG3547	Transposase (IS116 IS110 IS902 family)
J5276_RS26110	COG4221	oxidoreductase activity
J5276_RS26130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS26140	COG0765	amino acid transport
J5276_RS26145	COG0765	amino acid transport
J5276_RS26165	COG3622	Belongs to the hyi family
J5276_RS26175	COG3395	kinase activity
J5276_RS26180	COG0235	Class ii aldolase
J5276_RS26330	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
J5276_RS26335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_RS26360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5276_RS26365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_RS26455	COG4221	oxidoreductase activity
J5276_RS26475	COG4221	oxidoreductase activity
J5276_RS26480	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS26490	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS26500	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS26515	COG1741	Belongs to the pirin family
J5276_RS26520	COG0583	DNA-binding transcription factor activity
J5276_RS26560	COG1120	ATPase activity
J5276_RS26565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS26570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS26575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J5276_RS26580	COG4774	siderophore transport
J5276_RS26580	COG1629	transport
J5276_RS26590	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
J5276_RS26635	COG2226	methyltransferase
J5276_RS26645	COG0318	PFAM AMP-dependent synthetase and ligase
J5276_RS26665	COG0534	Mate efflux family protein
J5276_RS26675	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J5276_RS26690	COG3609	addiction module antidote protein, CC2985 family
J5276_RS26705	COG1902	pentaerythritol trinitrate reductase activity
J5276_RS26710	COG1609	Transcriptional regulator
J5276_RS26720	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS26735	COG0673	inositol 2-dehydrogenase activity
J5276_RS26745	COG1802	Transcriptional regulator
J5276_RS26780	COG0840	transmembrane signaling receptor activity
J5276_RS26815	COG0587	DNA-directed DNA polymerase activity
J5276_RS26835	COG5489	Protein of unknown function (DUF736)
J5276_RS26845	COG0776	regulation of translation
J5276_RS26850	COG3831	ATPase activity
J5276_RS26875	COG0577	efflux transmembrane transporter activity
J5276_RS26885	COG1414	Transcriptional regulator
J5276_RS26895	COG1454	alcohol dehydrogenase
J5276_RS26900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5276_RS26955	COG3838	Conjugal transfer protein Trbc
J5276_RS26960	COG3702	type iv secretory pathway
J5276_RS26965	COG3451	type IV secretory pathway VirB4
J5276_RS26980	COG3704	protein secretion by the type IV secretion system
J5276_RS26990	COG3736	Type IV secretory pathway, component VirB8
J5276_RS26995	COG3504	Conjugal transfer protein
J5276_RS27000	COG2948	multi-organism process
J5276_RS27005	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
J5276_RS27020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5276_RS27025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5276_RS27035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5276_RS27055	COG0784	Response regulator, receiver
J5276_RS27055	COG4191	Histidine kinase
J5276_RS27070	COG4691	Plasmid stability protein
J5276_RS27075	COG1487	ribonuclease activity
J5276_RS27080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_RS27090	COG2186	Transcriptional regulator
J5276_RS27095	COG0747	negative chemotaxis
J5276_RS27100	COG0601	transmembrane transport
J5276_RS27105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS27110	COG4172	Belongs to the ABC transporter superfamily
J5276_RS27115	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_RS27135	COG1595	DNA-templated transcription, initiation
J5276_RS27150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J5276_RS27160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS27165	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_RS27170	COG1120	ATPase activity
J5276_RS27180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5276_RS27185	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5276_RS27200	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J5276_RS27230	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_RS27235	COG3842	ATPase activity
J5276_RS27240	COG0483	inositol monophosphate 1-phosphatase activity
J5276_RS27245	COG0628	permease
J5276_RS27260	COG3734	2-keto-3-deoxy-galactonokinase
J5276_RS27265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_RS27270	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_RS27280	COG1175	transmembrane transport
J5276_RS27285	COG0395	ABC-type sugar transport system, permease component
J5276_RS27290	COG3842	ATPase activity
J5276_RS27295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5276_RS27300	COG1414	Transcriptional regulator
J5276_RS27305	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS27310	COG2207	Transcriptional regulator
J5276_RS27320	COG0583	DNA-binding transcription factor activity
J5276_RS27325	COG0667	Aldo Keto reductase
J5276_RS27330	COG0583	DNA-binding transcription factor activity
J5276_RS27335	COG0604	alcohol dehydrogenase
J5276_RS27340	COG1609	Transcriptional regulator
J5276_RS27345	COG1082	Xylose isomerase domain protein TIM barrel
J5276_RS27350	COG0673	inositol 2-dehydrogenase activity
J5276_RS27355	COG1082	Xylose isomerase domain protein TIM barrel
J5276_RS27365	COG0405	Gamma-glutamyltransferase
J5276_RS27370	COG1120	ATPase activity
J5276_RS27385	COG4774	siderophore transport
J5276_RS27405	COG1215	transferase activity, transferring glycosyl groups
J5276_RS27435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5276_RS27450	COG2390	Transcriptional regulator
J5276_RS27455	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J5276_RS27460	COG3958	Transketolase
J5276_RS27465	COG3959	Transketolase, thiamine diphosphate binding domain
J5276_RS27470	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS27480	COG1129	ABC transporter
J5276_RS27485	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS27490	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5276_RS27515	COG3547	Transposase (IS116 IS110 IS902 family)
J5276_RS27520	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS27540	COG0583	DNA-binding transcription factor activity
J5276_RS27555	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
J5276_RS27560	COG1741	Belongs to the pirin family
J5276_RS27565	COG1335	isochorismatase
J5276_RS27570	COG0583	DNA-binding transcription factor activity
J5276_RS27575	COG1733	regulation of RNA biosynthetic process
J5276_RS27580	COG0604	alcohol dehydrogenase
J5276_RS27580	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS27580	COG3321	synthase
J5276_RS27585	COG0583	DNA-binding transcription factor activity
J5276_RS27605	COG1017	nitric oxide dioxygenase activity
J5276_RS27605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J5276_RS27610	COG0625	glutathione transferase activity
J5276_RS27620	COG0583	DNA-binding transcription factor activity
J5276_RS27645	COG1349	DNA-binding transcription factor activity
J5276_RS27650	COG1879	ABC-type sugar transport system periplasmic component
J5276_RS27655	COG1129	ABC transporter
J5276_RS27660	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS27665	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS27685	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS27690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5276_RS27730	COG4302	ethanolamine ammonia-lyase activity
J5276_RS27755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5276_RS27760	COG1349	DNA-binding transcription factor activity
J5276_RS27765	COG4608	Belongs to the ABC transporter superfamily
J5276_RS27775	COG0601	transmembrane transport
J5276_RS27780	COG0747	negative chemotaxis
J5276_RS27805	COG0534	Mate efflux family protein
J5276_RS27810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5276_RS27830	COG4774	siderophore transport
J5276_RS27835	COG1309	transcriptional regulator
J5276_RS27845	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J5276_RS27850	COG1454	alcohol dehydrogenase
J5276_RS27860	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_RS27865	COG0747	negative chemotaxis
J5276_RS27870	COG0747	negative chemotaxis
J5276_RS27875	COG0601	transmembrane transport
J5276_RS27880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS27890	COG4172	Belongs to the ABC transporter superfamily
J5276_RS27945	COG2963	transposase activity
J5276_RS27950	COG3436	PFAM IS66 Orf2 family protein
J5276_RS27965	COG0583	DNA-binding transcription factor activity
J5276_RS27980	COG1309	transcriptional regulator
J5276_RS27995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS28000	COG4215	(ABC) transporter
J5276_RS28010	COG0697	spore germination
J5276_RS28030	COG0835	chemotaxis
J5276_RS28035	COG0840	transmembrane signaling receptor activity
J5276_RS28045	COG2207	Transcriptional regulator
J5276_RS28055	COG1129	ABC transporter
J5276_RS28060	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS28080	COG3706	GGDEF domain
J5276_RS28110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5276_RS28145	COG5001	Diguanylate cyclase
J5276_RS28190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_RS28205	COG1902	pentaerythritol trinitrate reductase activity
J5276_RS28215	COG0583	DNA-binding transcription factor activity
J5276_RS28220	COG4702	Belongs to the UPF0303 family
J5276_RS28225	COG0823	Involved in the tonB-independent uptake of proteins
J5276_RS28240	COG3842	ATPase activity
J5276_RS28250	COG1175	transmembrane transport
J5276_RS28255	COG1653	transport
J5276_RS28300	COG2963	transposase activity
J5276_RS28310	COG4372	Transposase
J5276_RS28320	COG1733	regulation of RNA biosynthetic process
J5276_RS28355	COG0436	Aminotransferase
J5276_RS28430	COG0745	RESPONSE REGULATOR receiver
J5276_RS28440	COG1192	Involved in chromosome partitioning
J5276_RS28530	COG1475	DNA binding
J5276_RS28535	COG0640	Transcriptional regulator
J5276_RS28560	COG3436	PFAM IS66 Orf2 family protein
J5276_RS28625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS28630	COG0584	glycerophosphoryl diester phosphodiesterase
J5276_RS28635	COG0483	inositol monophosphate 1-phosphatase activity
J5276_RS28735	COG1396	sequence-specific DNA binding
J5276_RS28775	COG0776	regulation of translation
J5276_RS28780	COG3831	ATPase activity
J5276_RS28865	COG0625	glutathione transferase activity
J5276_RS28880	COG1802	Transcriptional regulator
J5276_RS28895	COG0411	ABC transporter
J5276_RS28910	COG2084	Dehydrogenase
J5276_RS28915	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5276_RS28920	COG0346	lactoylglutathione lyase activity
J5276_RS28930	COG2814	Major facilitator Superfamily
J5276_RS28950	COG3842	ATPase activity
J5276_RS28960	COG1177	transmembrane transport
J5276_RS28970	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_RS28975	COG1177	transmembrane transport
J5276_RS28980	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J5276_RS28985	COG3842	ATPase activity
J5276_RS28990	COG1012	belongs to the aldehyde dehydrogenase family
J5276_RS28995	COG0747	negative chemotaxis
J5276_RS29005	COG4372	Transposase
J5276_RS29010	COG3436	PFAM IS66 Orf2 family protein
J5276_RS29015	COG2963	transposase activity
J5276_RS29025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_RS29045	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_RS29050	COG3842	ATPase activity
J5276_RS29055	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_RS29080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS29085	COG4172	Belongs to the ABC transporter superfamily
J5276_RS29095	COG1063	alcohol dehydrogenase
J5276_RS29120	COG3842	ATPase activity
J5276_RS29130	COG0698	ribose 5-phosphate isomerase
J5276_RS29135	COG0395	ABC-type sugar transport system, permease component
J5276_RS29140	COG1175	transmembrane transport
J5276_RS29160	COG1902	pentaerythritol trinitrate reductase activity
J5276_RS29185	COG3436	PFAM IS66 Orf2 family protein
J5276_RS29190	COG2963	transposase activity
J5276_RS29270	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
J5276_RS29285	COG2197	response regulator
J5276_RS29340	COG1216	Glycosyl transferase, family 2
J5276_RS29360	COG3916	Acyl-homoserine-lactone synthase
J5276_RS29365	COG2197	response regulator
J5276_RS29370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5276_RS29375	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5276_RS29405	COG0071	Belongs to the small heat shock protein (HSP20) family
J5276_RS29425	COG1278	Cold shock
J5276_RS29475	COG2963	transposase activity
J5276_RS29480	COG3436	PFAM IS66 Orf2 family protein
J5276_RS29485	COG4372	Transposase
J5276_RS29500	COG3620	sequence-specific DNA binding
J5276_RS29505	COG3550	peptidyl-serine autophosphorylation
J5276_RS29525	COG3077	Addiction module antitoxin, RelB DinJ family
J5276_RS29540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_RS29550	COG0596	Alpha beta hydrolase
J5276_RS29580	COG1454	alcohol dehydrogenase
J5276_RS29590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J5276_RS29640	COG0668	transmembrane transport
J5276_RS29655	COG1566	PFAM secretion protein HlyD family protein
J5276_RS29670	COG2207	Transcriptional regulator
J5276_RS29680	COG4302	ethanolamine ammonia-lyase activity
J5276_RS29685	COG4303	Ethanolamine ammonia lyase large subunit
J5276_RS29705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5276_RS29710	COG1349	DNA-binding transcription factor activity
J5276_RS29715	COG4608	Belongs to the ABC transporter superfamily
J5276_RS29725	COG0601	transmembrane transport
J5276_RS29730	COG0747	negative chemotaxis
J5276_RS29745	COG3842	ATPase activity
J5276_RS29750	COG1063	alcohol dehydrogenase
J5276_RS29755	COG0395	ABC-type sugar transport system, permease component
J5276_RS29760	COG1175	transmembrane transport
J5276_RS29765	COG1653	transport
J5276_RS29795	COG0326	Molecular chaperone. Has ATPase activity
J5276_RS29805	COG1881	PFAM PEBP family protein
J5276_RS29830	COG0778	Nitroreductase
J5276_RS29835	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J5276_RS29850	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5276_RS29875	COG0583	DNA-binding transcription factor activity
J5276_RS29880	COG0667	Aldo Keto reductase
J5276_RS29910	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_RS29945	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_RS29965	COG1278	Cold shock
J5276_RS29985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_RS29990	COG1609	Transcriptional regulator
J5276_RS29995	COG1192	Involved in chromosome partitioning
J5276_RS30000	COG1475	DNA binding
J5276_RS30005	COG0640	Transcriptional regulator
J5276_RS30020	COG0583	DNA-binding transcription factor activity
J5276_RS30050	COG3971	2-oxopent-4-enoate hydratase activity
J5276_RS30055	COG3485	protocatechuate 3,4-dioxygenase
J5276_RS30160	COG0835	chemotaxis
J5276_RS30170	COG0546	phosphoglycolate phosphatase activity
J5276_RS30180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J5276_RS30210	COG1192	Involved in chromosome partitioning
J5276_RS30275	COG0799	negative regulation of ribosome biogenesis
J5276_RS30400	COG1126	abc transporter atp-binding protein
J5276_RS30460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5276_RS30505	COG0165	Argininosuccinate lyase
J5276_RS30520	COG0582	viral genome integration into host DNA
J5276_RS30615	COG3293	Transposase
J5276_RS30625	COG3344	reverse transcriptase
J5276_RS30630	COG4372	Transposase
J5276_RS30715	COG1126	abc transporter atp-binding protein