locus-tag	class	description
FGF54_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FGF54_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGF54_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGF54_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FGF54_RS00025	COG1420	regulation of RNA biosynthetic process
FGF54_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGF54_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGF54_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FGF54_RS00050	COG1137	ATPase activity
FGF54_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FGF54_RS00065	COG0616	signal peptide processing
FGF54_RS00070	COG0776	regulation of translation
FGF54_RS00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FGF54_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGF54_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FGF54_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FGF54_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FGF54_RS00115	COG0728	peptidoglycan biosynthetic process
FGF54_RS00125	COG0180	Tryptophanyl-tRNA synthetase
FGF54_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FGF54_RS00140	COG1214	PFAM Peptidase M22, glycoprotease
FGF54_RS00145	COG0456	acetyltransferase
FGF54_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGF54_RS00165	COG1702	phosphate starvation-inducible protein PhoH
FGF54_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGF54_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FGF54_RS00185	COG1396	sequence-specific DNA binding
FGF54_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FGF54_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FGF54_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGF54_RS00210	COG0242	peptide deformylase activity
FGF54_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGF54_RS00220	COG0101	tRNA pseudouridine synthase activity
FGF54_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGF54_RS00235	COG2171	N-acyltransferase activity
FGF54_RS00245	COG0840	transmembrane signaling receptor activity
FGF54_RS00250	COG1957	nucleoside hydrolase
FGF54_RS00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FGF54_RS00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGF54_RS00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FGF54_RS00295	COG0706	membrane insertase activity
FGF54_RS00300	COG0594	ribonuclease P activity
FGF54_RS00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FGF54_RS00310	COG0840	transmembrane signaling receptor activity
FGF54_RS00330	COG2226	methyltransferase
FGF54_RS00335	COG3842	ATPase activity
FGF54_RS00340	COG1175	transmembrane transport
FGF54_RS00345	COG0395	ABC-type sugar transport system, permease component
FGF54_RS00360	COG0427	acetyl-CoA hydrolase
FGF54_RS00370	COG3938	Belongs to the proline racemase family
FGF54_RS00375	COG0418	dihydroorotase activity
FGF54_RS00380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGF54_RS00400	COG0166	Belongs to the GPI family
FGF54_RS00405	COG0318	PFAM AMP-dependent synthetase and ligase
FGF54_RS00410	COG3842	ATPase activity
FGF54_RS00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FGF54_RS00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FGF54_RS00425	COG4774	siderophore transport
FGF54_RS00485	COG2326	polyphosphate kinase activity
FGF54_RS00490	COG5002	protein histidine kinase activity
FGF54_RS00495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FGF54_RS00500	COG0573	inorganic phosphate transmembrane transporter activity
FGF54_RS00510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FGF54_RS00515	COG0704	Plays a role in the regulation of phosphate uptake
FGF54_RS00520	COG0745	RESPONSE REGULATOR receiver
FGF54_RS00535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGF54_RS00540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGF54_RS00550	COG2967	ApaG domain
FGF54_RS00560	COG0717	Belongs to the dCTP deaminase family
FGF54_RS00570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGF54_RS00620	COG0167	dihydroorotate dehydrogenase activity
FGF54_RS00635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FGF54_RS00655	COG1959	2 iron, 2 sulfur cluster binding
FGF54_RS00660	COG1201	RNA secondary structure unwinding
FGF54_RS00695	COG1960	acyl-CoA dehydrogenase activity
FGF54_RS00700	COG0183	Belongs to the thiolase family
FGF54_RS00705	COG1024	Enoyl-CoA hydratase
FGF54_RS00705	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGF54_RS00745	COG1320	monovalent cation:proton antiporter activity
FGF54_RS00750	COG2212	antiporter activity
FGF54_RS00755	COG1863	multisubunit Na H antiporter MnhE subunit
FGF54_RS00760	COG0651	ATP synthesis coupled electron transport
FGF54_RS00765	COG1006	Multisubunit Na H antiporter MnhC subunit
FGF54_RS00770	COG2111	Na H antiporter
FGF54_RS00770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FGF54_RS00780	COG0840	transmembrane signaling receptor activity
FGF54_RS00790	COG0745	RESPONSE REGULATOR receiver
FGF54_RS00795	COG2198	Histidine kinase
FGF54_RS00795	COG0643	Histidine kinase
FGF54_RS00800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FGF54_RS00805	COG2201	protein-glutamate methylesterase activity
FGF54_RS00810	COG0745	RESPONSE REGULATOR receiver
FGF54_RS00815	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FGF54_RS00825	COG1766	The M ring may be actively involved in energy transduction
FGF54_RS00830	COG2771	luxR family
FGF54_RS00840	COG0840	transmembrane signaling receptor activity
FGF54_RS00840	COG2972	Histidine kinase
FGF54_RS00845	COG0784	Response regulator, receiver
FGF54_RS00845	COG2205	protein histidine kinase activity
FGF54_RS00845	COG2198	Histidine kinase
FGF54_RS00850	COG1970	mechanosensitive ion channel activity
FGF54_RS00855	COG0436	Aminotransferase
FGF54_RS00870	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FGF54_RS00875	COG0424	maF-like protein
FGF54_RS00880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FGF54_RS00890	COG5328	Belongs to the UPF0262 family
FGF54_RS00895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FGF54_RS00905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGF54_RS00950	COG1338	Plays a role in the flagellum-specific transport system
FGF54_RS00960	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FGF54_RS00970	COG1706	bacterial-type flagellum-dependent cell motility
FGF54_RS00975	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FGF54_RS00980	COG4786	Flagellar basal body rod
FGF54_RS00985	COG1677	Flagellar hook-basal body complex protein FliE
FGF54_RS00990	COG1558	bacterial-type flagellum-dependent cell motility
FGF54_RS00995	COG1815	bacterial-type flagellum-dependent cell motility
FGF54_RS01005	COG1157	protein secretion by the type III secretion system
FGF54_RS01010	COG4786	Flagellar basal body rod
FGF54_RS01020	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGF54_RS01025	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FGF54_RS01030	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FGF54_RS01035	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FGF54_RS01040	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FGF54_RS01065	COG1360	Flagellar Motor Protein
FGF54_RS01110	COG5443	negative regulation of bacterial-type flagellum assembly
FGF54_RS01115	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FGF54_RS01125	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FGF54_RS01165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FGF54_RS01170	COG1609	Transcriptional regulator
FGF54_RS01175	COG1653	transport
FGF54_RS01180	COG1175	transmembrane transport
FGF54_RS01185	COG0395	ABC-type sugar transport system, permease component
FGF54_RS01190	COG0366	Alpha amylase catalytic
FGF54_RS01195	COG3842	ATPase activity
FGF54_RS01205	COG3609	addiction module antidote protein, CC2985 family
FGF54_RS01220	COG0129	dihydroxy-acid dehydratase activity
FGF54_RS01225	COG0363	glucosamine-6-phosphate deaminase activity
FGF54_RS01230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FGF54_RS01235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS01245	COG2081	HI0933 family
FGF54_RS01265	COG2224	Isocitrate lyase
FGF54_RS01280	COG3842	ATPase activity
FGF54_RS01285	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGF54_RS01290	COG1177	transmembrane transport
FGF54_RS01300	COG2205	protein histidine kinase activity
FGF54_RS01325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FGF54_RS01340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FGF54_RS01345	COG1984	allophanate hydrolase subunit 2
FGF54_RS01350	COG1802	Transcriptional regulator
FGF54_RS01370	COG0006	proline dipeptidase activity
FGF54_RS01395	COG0765	amino acid transport
FGF54_RS01420	COG3665	Urea carboxylase-associated protein
FGF54_RS01425	COG1116	anion transmembrane transporter activity
FGF54_RS01450	COG0395	ABC-type sugar transport system, permease component
FGF54_RS01455	COG3842	ATPase activity
FGF54_RS01465	COG1063	alcohol dehydrogenase
FGF54_RS01470	COG4948	Mandelate Racemase Muconate Lactonizing
FGF54_RS01475	COG4948	Mandelate Racemase Muconate Lactonizing
FGF54_RS01480	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS01485	COG0248	Ppx GppA phosphatase
FGF54_RS01490	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FGF54_RS01500	COG0477	Major facilitator Superfamily
FGF54_RS01535	COG0521	Mo-molybdopterin cofactor biosynthetic process
FGF54_RS01540	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FGF54_RS01550	COG0142	geranyltranstransferase activity
FGF54_RS01585	COG0752	glycyl-tRNA synthetase alpha subunit
FGF54_RS01590	COG1704	LemA family
FGF54_RS01595	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FGF54_RS01605	COG0751	glycine-tRNA ligase activity
FGF54_RS01615	COG1683	Conserved Protein
FGF54_RS01620	COG0840	transmembrane signaling receptor activity
FGF54_RS01630	COG0151	Belongs to the GarS family
FGF54_RS01635	COG2183	response to ionizing radiation
FGF54_RS01640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGF54_RS01655	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FGF54_RS01670	COG0583	DNA-binding transcription factor activity
FGF54_RS01690	COG0306	phosphate transporter
FGF54_RS01700	COG0561	phosphatase activity
FGF54_RS01705	COG0438	transferase activity, transferring glycosyl groups
FGF54_RS01710	COG2186	Transcriptional regulator
FGF54_RS01720	COG0583	DNA-binding transcription factor activity
FGF54_RS01725	COG0277	FAD linked oxidase domain protein
FGF54_RS01735	COG0277	FAD linked oxidase domain protein
FGF54_RS01740	COG0247	lactate metabolic process
FGF54_RS01750	COG1376	ErfK ybiS ycfS ynhG family protein
FGF54_RS01755	COG2818	Glycosylase
FGF54_RS01765	COG2855	membrane
FGF54_RS01770	COG0583	DNA-binding transcription factor activity
FGF54_RS01800	COG0124	histidyl-tRNA synthetase
FGF54_RS01805	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FGF54_RS01810	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FGF54_RS01815	COG2259	Doxx family
FGF54_RS01825	COG0459	protein refolding
FGF54_RS01830	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGF54_RS01840	COG0196	riboflavin kinase activity
FGF54_RS01845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FGF54_RS01855	COG0590	tRNA wobble adenosine to inosine editing
FGF54_RS01860	COG1187	pseudouridine synthase activity
FGF54_RS01865	COG0742	ribosomal rna small subunit methyltransferase
FGF54_RS01870	COG1752	Esterase of the alpha-beta hydrolase superfamily
FGF54_RS01875	COG0475	glutathione-regulated potassium exporter activity
FGF54_RS01875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FGF54_RS01885	COG0312	modulator of DNA gyrase
FGF54_RS01890	COG0483	inositol monophosphate 1-phosphatase activity
FGF54_RS01900	COG1519	Transferase
FGF54_RS01910	COG1663	tetraacyldisaccharide 4'-kinase activity
FGF54_RS01925	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGF54_RS01930	COG0745	RESPONSE REGULATOR receiver
FGF54_RS01935	COG3300	MHYT domain
FGF54_RS01935	COG5001	Diguanylate cyclase
FGF54_RS01940	COG3386	PFAM SMP-30 Gluconolaconase
FGF54_RS01945	COG0800	Aldolase
FGF54_RS01950	COG3734	2-keto-3-deoxy-galactonokinase
FGF54_RS01955	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS01960	COG1414	Transcriptional regulator
FGF54_RS01965	COG2197	response regulator
FGF54_RS01980	COG0598	Magnesium transport protein CorA
FGF54_RS01985	COG3158	transport of potassium into the cell
FGF54_RS02000	COG0356	it plays a direct role in the translocation of protons across the membrane
FGF54_RS02010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGF54_RS02015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGF54_RS02025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGF54_RS02045	COG0009	L-threonylcarbamoyladenylate synthase
FGF54_RS02055	COG4638	Rieske (2fe-2S)
FGF54_RS02080	COG1960	acyl-CoA dehydrogenase activity
FGF54_RS02095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGF54_RS02100	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FGF54_RS02105	COG0840	transmembrane signaling receptor activity
FGF54_RS02115	COG1522	sequence-specific DNA binding
FGF54_RS02140	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FGF54_RS02145	COG1741	Belongs to the pirin family
FGF54_RS02155	COG1722	exodeoxyribonuclease VII activity
FGF54_RS02160	COG0123	including yeast histone deacetylase and acetoin utilization protein
FGF54_RS02165	COG1268	BioY protein
FGF54_RS02170	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FGF54_RS02175	COG1122	ATPase activity
FGF54_RS02180	COG3214	Protein conserved in bacteria
FGF54_RS02185	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGF54_RS02185	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGF54_RS02190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FGF54_RS02210	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGF54_RS02225	COG0259	pyridoxamine-phosphate oxidase activity
FGF54_RS02260	COG0312	modulator of DNA gyrase
FGF54_RS02275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FGF54_RS02280	COG0109	protoheme IX farnesyltransferase activity
FGF54_RS02290	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FGF54_RS02305	COG3346	SURF1 family
FGF54_RS02310	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FGF54_RS02315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FGF54_RS02320	COG0328	RNA-DNA hybrid ribonuclease activity
FGF54_RS02330	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FGF54_RS02330	COG0678	peroxiredoxin activity
FGF54_RS02340	COG1678	Uncharacterized ACR, COG1678
FGF54_RS02360	COG3300	MHYT domain
FGF54_RS02360	COG5001	Diguanylate cyclase
FGF54_RS02365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGF54_RS02370	COG0612	Peptidase, M16
FGF54_RS02390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGF54_RS02395	COG1802	Transcriptional regulator
FGF54_RS02415	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FGF54_RS02425	COG3609	addiction module antidote protein, CC2985 family
FGF54_RS02430	COG3668	Plasmid stabilization system
FGF54_RS02440	COG1194	a g-specific adenine glycosylase
FGF54_RS02455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FGF54_RS02460	COG1196	nuclear chromosome segregation
FGF54_RS02465	COG2514	catechol 2,3-dioxygenase activity
FGF54_RS02470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGF54_RS02470	COG0574	Belongs to the PEP-utilizing enzyme family
FGF54_RS02485	COG1823	symporter activity
FGF54_RS02515	COG0579	oxidoreductase
FGF54_RS02535	COG2895	sulfate adenylyltransferase (ATP) activity
FGF54_RS02540	COG0175	sulfate reduction
FGF54_RS02545	COG0175	sulfate reduction
FGF54_RS02555	COG1959	2 iron, 2 sulfur cluster binding
FGF54_RS02565	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FGF54_RS02570	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FGF54_RS02575	COG4208	sulfate ABC transporter
FGF54_RS02580	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FGF54_RS02605	COG2200	EAL domain
FGF54_RS02605	COG2203	Gaf domain
FGF54_RS02605	COG2199	diguanylate cyclase activity
FGF54_RS02620	COG1309	transcriptional regulator
FGF54_RS02625	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS02635	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FGF54_RS02680	COG0477	Major facilitator Superfamily
FGF54_RS02700	COG1793	dna ligase
FGF54_RS02720	COG1376	ErfK ybiS ycfS ynhG family protein
FGF54_RS02725	COG1376	ErfK ybiS ycfS ynhG family protein
FGF54_RS02730	COG1846	Transcriptional regulator
FGF54_RS02735	COG1764	response to oxidative stress
FGF54_RS02750	COG0488	(ABC) transporter
FGF54_RS02780	COG0583	DNA-binding transcription factor activity
FGF54_RS02785	COG4221	oxidoreductase activity
FGF54_RS02795	COG0433	COG0433 Predicted ATPase
FGF54_RS02810	COG1733	regulation of RNA biosynthetic process
FGF54_RS02815	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS02830	COG0656	L-ascorbic acid biosynthetic process
FGF54_RS02835	COG3781	membrane
FGF54_RS02840	COG2378	regulation of single-species biofilm formation
FGF54_RS02855	COG4106	trans-aconitate 2-methyltransferase activity
FGF54_RS02860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGF54_RS02865	COG0840	transmembrane signaling receptor activity
FGF54_RS02870	COG0583	DNA-binding transcription factor activity
FGF54_RS02885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FGF54_RS02905	COG3909	cytochrome
FGF54_RS02910	COG2010	Cytochrome c
FGF54_RS02940	COG0789	Transcriptional regulator
FGF54_RS02970	COG0517	IMP dehydrogenase activity
FGF54_RS02970	COG4175	Glycine betaine
FGF54_RS02975	COG4176	ABC-type proline glycine betaine transport system permease component
FGF54_RS03005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGF54_RS03015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGF54_RS03015	COG2169	Transcriptional regulator
FGF54_RS03025	COG2514	catechol 2,3-dioxygenase activity
FGF54_RS03045	COG1272	protein, Hemolysin III
FGF54_RS03055	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGF54_RS03060	COG2111	Na H antiporter
FGF54_RS03060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FGF54_RS03065	COG2111	Na H antiporter
FGF54_RS03070	COG1006	Multisubunit Na H antiporter MnhC subunit
FGF54_RS03075	COG0651	ATP synthesis coupled electron transport
FGF54_RS03080	COG1863	multisubunit Na H antiporter MnhE subunit
FGF54_RS03085	COG2212	antiporter activity
FGF54_RS03090	COG1320	monovalent cation:proton antiporter activity
FGF54_RS03095	COG4957	zinc ion binding
FGF54_RS03110	COG2166	iron-sulfur cluster assembly
FGF54_RS03120	COG2205	protein histidine kinase activity
FGF54_RS03175	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FGF54_RS03180	COG2983	Belongs to the UPF0260 family
FGF54_RS03215	COG2337	Toxic component of a toxin-antitoxin (TA) module
FGF54_RS03225	COG0477	Major facilitator Superfamily
FGF54_RS03235	COG1621	beta-fructofuranosidase activity
FGF54_RS03240	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FGF54_RS03290	COG4695	Portal protein
FGF54_RS03405	COG4235	cytochrome complex assembly
FGF54_RS03410	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FGF54_RS03415	COG1138	Cytochrome C-type biogenesis protein
FGF54_RS03420	COG3088	subunit of a heme lyase
FGF54_RS03425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGF54_RS03430	COG0745	RESPONSE REGULATOR receiver
FGF54_RS03440	COG3011	Protein conserved in bacteria
FGF54_RS03455	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FGF54_RS03465	COG2202	Pas domain
FGF54_RS03465	COG2205	protein histidine kinase activity
FGF54_RS03475	COG0308	aminopeptidase N
FGF54_RS03480	COG0697	spore germination
FGF54_RS03500	COG0443	Heat shock 70 kDa protein
FGF54_RS03510	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS03555	COG0604	alcohol dehydrogenase
FGF54_RS03560	COG1733	regulation of RNA biosynthetic process
FGF54_RS03565	COG1968	undecaprenyl-diphosphatase activity
FGF54_RS03570	COG2239	Acts as a magnesium transporter
FGF54_RS03575	COG2814	Major facilitator Superfamily
FGF54_RS03605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FGF54_RS03635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGF54_RS03690	COG0741	lytic transglycosylase activity
FGF54_RS03700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGF54_RS03705	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FGF54_RS03710	COG0840	transmembrane signaling receptor activity
FGF54_RS03720	COG1758	RNA polymerase activity
FGF54_RS03745	COG0736	holo-[acyl-carrier-protein] synthase activity
FGF54_RS03750	COG0681	Belongs to the peptidase S26 family
FGF54_RS03755	COG0571	ribonuclease III activity
FGF54_RS03760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FGF54_RS03765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGF54_RS03770	COG0784	Response regulator, receiver
FGF54_RS03775	COG1381	Involved in DNA repair and RecF pathway recombination
FGF54_RS03785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGF54_RS03795	COG1418	mRNA catabolic process
FGF54_RS03805	COG0346	lactoylglutathione lyase activity
FGF54_RS03815	COG1116	anion transmembrane transporter activity
FGF54_RS03820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS03825	COG3443	Belongs to the bacterial solute-binding protein 9 family
FGF54_RS03830	COG0668	transmembrane transport
FGF54_RS03840	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FGF54_RS03845	COG0354	folic acid binding
FGF54_RS03870	COG1742	UPF0060 membrane protein
FGF54_RS03885	COG1183	phosphatidylcholine synthase activity
FGF54_RS03890	COG0688	phosphatidylethanolamine metabolic process
FGF54_RS03895	COG5265	(ABC) transporter
FGF54_RS03940	COG2852	Protein conserved in bacteria
FGF54_RS03950	COG0215	cysteine-tRNA ligase activity
FGF54_RS03955	COG4221	oxidoreductase activity
FGF54_RS03960	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FGF54_RS03965	COG1286	toxin biosynthetic process
FGF54_RS03985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGF54_RS03995	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FGF54_RS04005	COG5265	(ABC) transporter
FGF54_RS04010	COG0305	Participates in initiation and elongation during chromosome replication
FGF54_RS04035	COG0359	binds to the 23S rRNA
FGF54_RS04045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGF54_RS04050	COG0360	Binds together with S18 to 16S ribosomal RNA
FGF54_RS04060	COG0667	Aldo Keto reductase
FGF54_RS04065	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FGF54_RS04075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGF54_RS04080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGF54_RS04090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FGF54_RS04095	COG1561	YicC-like family, N-terminal region
FGF54_RS04100	COG0194	GDP metabolic process
FGF54_RS04115	COG0400	carboxylic ester hydrolase activity
FGF54_RS04120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGF54_RS04125	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FGF54_RS04135	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FGF54_RS04150	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FGF54_RS04170	COG4251	negative regulation of phosphorylation
FGF54_RS04170	COG5001	Diguanylate cyclase
FGF54_RS04170	COG3706	GGDEF domain
FGF54_RS04170	COG2203	Gaf domain
FGF54_RS04175	COG3300	MHYT domain
FGF54_RS04175	COG5001	Diguanylate cyclase
FGF54_RS04180	COG0488	(ABC) transporter
FGF54_RS04185	COG3706	GGDEF domain
FGF54_RS04195	COG0105	UTP biosynthetic process
FGF54_RS04215	COG0314	molybdopterin synthase activity
FGF54_RS04225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FGF54_RS04230	COG0322	excinuclease ABC activity
FGF54_RS04235	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS04245	COG0625	glutathione transferase activity
FGF54_RS04260	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FGF54_RS04265	COG0243	molybdopterin cofactor binding
FGF54_RS04280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FGF54_RS04285	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FGF54_RS04295	COG0628	permease
FGF54_RS04305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FGF54_RS04310	COG0248	Ppx GppA phosphatase
FGF54_RS04335	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FGF54_RS04345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FGF54_RS04350	COG0477	Major facilitator Superfamily
FGF54_RS04355	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FGF54_RS04365	COG0840	transmembrane signaling receptor activity
FGF54_RS04370	COG0659	secondary active sulfate transmembrane transporter activity
FGF54_RS04380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FGF54_RS04390	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FGF54_RS04405	COG0113	porphobilinogen synthase activity
FGF54_RS04430	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGF54_RS04435	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FGF54_RS04440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGF54_RS04440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGF54_RS04450	COG1280	lysine exporter protein (LysE YggA)
FGF54_RS04455	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FGF54_RS04460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGF54_RS04465	COG2814	Major facilitator Superfamily
FGF54_RS04470	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FGF54_RS04490	COG0416	fatty acid biosynthetic process
FGF54_RS04495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGF54_RS04500	COG0776	regulation of translation
FGF54_RS04535	COG0601	transmembrane transport
FGF54_RS04540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS04545	COG0444	Belongs to the ABC transporter superfamily
FGF54_RS04565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGF54_RS04570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FGF54_RS04585	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FGF54_RS04590	COG0583	DNA-binding transcription factor activity
FGF54_RS04605	COG0737	Belongs to the 5'-nucleotidase family
FGF54_RS04630	COG2897	thiosulfate sulfurtransferase activity
FGF54_RS04645	COG0415	Belongs to the DNA photolyase family
FGF54_RS04655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGF54_RS04685	COG3932	Exopolysaccharide synthesis, ExoD
FGF54_RS04690	COG1238	metal cluster binding
FGF54_RS04705	COG4139	cobalamin transport
FGF54_RS04710	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FGF54_RS04720	COG1528	Iron-storage protein
FGF54_RS04790	COG1612	heme a metabolic process
FGF54_RS04800	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FGF54_RS04805	COG0010	Belongs to the arginase family
FGF54_RS04810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FGF54_RS04815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FGF54_RS04830	COG1832	CoA-binding protein
FGF54_RS04840	COG1846	Transcriptional regulator
FGF54_RS04870	COG2124	cytochrome p450
FGF54_RS04875	COG3706	GGDEF domain
FGF54_RS04880	COG0740	serine-type endopeptidase activity
FGF54_RS04885	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FGF54_RS04895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FGF54_RS04905	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FGF54_RS04925	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGF54_RS04930	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGF54_RS04935	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGF54_RS04945	COG0649	NAD binding
FGF54_RS04955	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FGF54_RS04960	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FGF54_RS04970	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FGF54_RS04975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGF54_RS04985	COG0713	ATP synthesis coupled electron transport
FGF54_RS05000	COG1007	ATP synthesis coupled electron transport
FGF54_RS05005	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FGF54_RS05005	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FGF54_RS05020	COG0442	prolyl-tRNA aminoacylation
FGF54_RS05030	COG1136	(ABC) transporter
FGF54_RS05050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGF54_RS05060	COG0784	Response regulator, receiver
FGF54_RS05075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGF54_RS05080	COG0477	Major facilitator Superfamily
FGF54_RS05095	COG0557	exoribonuclease II activity
FGF54_RS05100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGF54_RS05110	COG0758	DNA mediated transformation
FGF54_RS05115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FGF54_RS05125	COG0540	Belongs to the ATCase OTCase family
FGF54_RS05135	COG1960	acyl-CoA dehydrogenase activity
FGF54_RS05140	COG0456	acetyltransferase
FGF54_RS05165	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FGF54_RS05170	COG2824	Alkylphosphonate utilization operon protein PhnA
FGF54_RS05175	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FGF54_RS05180	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGF54_RS05185	COG0154	amidase activity
FGF54_RS05190	COG3811	Belongs to the UPF0386 family
FGF54_RS05205	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGF54_RS05215	COG0456	acetyltransferase
FGF54_RS05235	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FGF54_RS05240	COG0439	Biotin carboxylase
FGF54_RS05245	COG0511	ligase activity, forming carbon-carbon bonds
FGF54_RS05250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FGF54_RS05260	COG0436	Aminotransferase
FGF54_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS05285	COG1530	ribonuclease E activity
FGF54_RS05300	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FGF54_RS05320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGF54_RS05325	COG0384	phenazine biosynthesis protein PhzF
FGF54_RS05340	COG0633	Ferredoxin
FGF54_RS05350	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FGF54_RS05355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FGF54_RS05360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FGF54_RS05370	COG3768	UPF0283 membrane protein
FGF54_RS05375	COG3106	COG3106 Predicted ATPase
FGF54_RS05405	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FGF54_RS05440	COG0537	adenosine 5'-monophosphoramidase activity
FGF54_RS05465	COG0052	Belongs to the universal ribosomal protein uS2 family
FGF54_RS05470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FGF54_RS05475	COG0528	UMP kinase activity
FGF54_RS05480	COG0233	cytoplasmic translational termination
FGF54_RS05485	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FGF54_RS05495	COG0750	zinc metalloprotease
FGF54_RS05500	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGF54_RS05505	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGF54_RS05510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGF54_RS05515	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGF54_RS05520	COG3494	Protein of unknown function (DUF1009)
FGF54_RS05525	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGF54_RS05530	COG2186	Transcriptional regulator
FGF54_RS05540	COG0765	amino acid transport
FGF54_RS05545	COG0765	amino acid transport
FGF54_RS05555	COG0372	Belongs to the citrate synthase family
FGF54_RS05570	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FGF54_RS05575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FGF54_RS05580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FGF54_RS05585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FGF54_RS05590	COG3958	Transketolase
FGF54_RS05595	COG3959	Transketolase, thiamine diphosphate binding domain
FGF54_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS05605	COG0583	DNA-binding transcription factor activity
FGF54_RS05615	COG2376	Dihydroxyacetone kinase
FGF54_RS05635	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FGF54_RS05640	COG0148	phosphopyruvate hydratase activity
FGF54_RS05650	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FGF54_RS05655	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGF54_RS05655	COG0022	dehydrogenase e1 component
FGF54_RS05660	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGF54_RS05670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGF54_RS05680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FGF54_RS05685	COG0697	spore germination
FGF54_RS05700	COG2867	negative regulation of translational initiation
FGF54_RS05710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FGF54_RS05710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FGF54_RS05720	COG3852	Histidine kinase
FGF54_RS05725	COG2204	response regulator
FGF54_RS05730	COG5000	phosphorelay sensor kinase activity
FGF54_RS05735	COG2204	response regulator
FGF54_RS05740	COG0569	domain protein
FGF54_RS05745	COG1923	regulation of RNA biosynthetic process
FGF54_RS05750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FGF54_RS05755	COG3956	TIGRFAM MazG family protein
FGF54_RS05770	COG1648	precorrin-2 dehydrogenase activity
FGF54_RS05770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGF54_RS05810	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FGF54_RS05815	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGF54_RS05815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGF54_RS05820	COG0509	glycine decarboxylation via glycine cleavage system
FGF54_RS05825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGF54_RS05850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGF54_RS05880	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FGF54_RS05890	COG1671	Belongs to the UPF0178 family
FGF54_RS05905	COG0450	alkyl hydroperoxide reductase
FGF54_RS05915	COG0625	glutathione transferase activity
FGF54_RS05940	COG1079	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS05955	COG0436	Aminotransferase
FGF54_RS05980	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS06020	COG0431	NADPH-dependent FMN reductase
FGF54_RS06030	COG0798	PFAM Bile acid sodium symporter
FGF54_RS06050	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS06060	COG0604	alcohol dehydrogenase
FGF54_RS06060	COG3321	synthase
FGF54_RS06065	COG0604	alcohol dehydrogenase
FGF54_RS06065	COG3321	synthase
FGF54_RS06105	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FGF54_RS06105	COG0321	lipoyl(octanoyl) transferase activity
FGF54_RS06110	COG0084	hydrolase, TatD family'
FGF54_RS06115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGF54_RS06125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FGF54_RS06180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FGF54_RS06185	COG2095	MarC family integral membrane protein
FGF54_RS06190	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FGF54_RS06190	COG0517	IMP dehydrogenase activity
FGF54_RS06190	COG0617	tRNA 3'-terminal CCA addition
FGF54_RS06200	COG0629	single-stranded DNA binding
FGF54_RS06205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGF54_RS06215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGF54_RS06235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGF54_RS06240	COG1121	(ABC) transporter
FGF54_RS06260	COG0667	Aldo Keto reductase
FGF54_RS06270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FGF54_RS06350	COG2239	Acts as a magnesium transporter
FGF54_RS06355	COG0243	molybdopterin cofactor binding
FGF54_RS06365	COG0242	peptide deformylase activity
FGF54_RS06380	COG2202	Pas domain
FGF54_RS06380	COG2205	protein histidine kinase activity
FGF54_RS06395	COG0321	lipoyl(octanoyl) transferase activity
FGF54_RS06400	COG1064	alcohol dehydrogenase
FGF54_RS06430	COG1862	Preprotein translocase
FGF54_RS06445	COG1309	transcriptional regulator
FGF54_RS06450	COG2124	cytochrome p450
FGF54_RS06465	COG0596	Alpha beta hydrolase
FGF54_RS06475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGF54_RS06480	COG0626	cystathionine gamma-synthase activity
FGF54_RS06485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGF54_RS06490	COG4597	amino acid ABC transporter
FGF54_RS06495	COG0765	amino acid transport
FGF54_RS06500	COG1126	abc transporter atp-binding protein
FGF54_RS06520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FGF54_RS06535	COG0436	Aminotransferase
FGF54_RS06565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGF54_RS06570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGF54_RS06575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGF54_RS06580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGF54_RS06585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGF54_RS06600	COG3243	poly(R)-hydroxyalkanoic acid synthase
FGF54_RS06605	COG1489	DNA binding
FGF54_RS06610	COG0024	Methionine aminopeptidase
FGF54_RS06615	COG2003	Belongs to the UPF0758 family
FGF54_RS06630	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FGF54_RS06645	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FGF54_RS06650	COG0546	phosphoglycolate phosphatase activity
FGF54_RS06660	COG0114	fumarate hydratase activity
FGF54_RS06665	COG0504	CTP synthase activity
FGF54_RS06675	COG0149	triose-phosphate isomerase activity
FGF54_RS06685	COG0187	DNA topoisomerase II activity
FGF54_RS06710	COG3064	Membrane
FGF54_RS06710	COG3210	domain, Protein
FGF54_RS06710	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FGF54_RS06735	COG3210	domain, Protein
FGF54_RS06810	COG0740	serine-type endopeptidase activity
FGF54_RS06820	COG0640	Transcriptional regulator
FGF54_RS06825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGF54_RS06830	COG0745	RESPONSE REGULATOR receiver
FGF54_RS06840	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FGF54_RS06840	COG3264	Mechanosensitive ion channel
FGF54_RS06900	COG1127	ABC transporter
FGF54_RS06905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FGF54_RS06910	COG4948	Mandelate Racemase Muconate Lactonizing
FGF54_RS06920	COG0280	phosphate acetyltransferase
FGF54_RS06920	COG0281	malic enzyme
FGF54_RS06930	COG0778	Nitroreductase
FGF54_RS06935	COG0823	Involved in the tonB-independent uptake of proteins
FGF54_RS06950	COG1368	sulfuric ester hydrolase activity
FGF54_RS06975	COG0544	peptidyl-prolyl cis-trans isomerase activity
FGF54_RS07000	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FGF54_RS07020	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FGF54_RS07035	COG0318	PFAM AMP-dependent synthetase and ligase
FGF54_RS07045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGF54_RS07045	COG0512	Glutamine amidotransferase of anthranilate synthase
FGF54_RS07050	COG0343	queuine tRNA-ribosyltransferase activity
FGF54_RS07055	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FGF54_RS07070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FGF54_RS07095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGF54_RS07100	COG0134	indole-3-glycerol-phosphate synthase activity
FGF54_RS07105	COG0315	cyclic pyranopterin monophosphate synthase activity
FGF54_RS07110	COG0303	'Molybdopterin
FGF54_RS07115	COG3706	GGDEF domain
FGF54_RS07125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FGF54_RS07125	COG0475	glutathione-regulated potassium exporter activity
FGF54_RS07135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FGF54_RS07140	COG0697	spore germination
FGF54_RS07145	COG2814	Major facilitator Superfamily
FGF54_RS07150	COG0746	molybdenum cofactor guanylyltransferase activity
FGF54_RS07155	COG1763	Mo-molybdopterin cofactor biosynthetic process
FGF54_RS07165	COG0739	heme binding
FGF54_RS07170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FGF54_RS07175	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FGF54_RS07180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGF54_RS07185	COG0805	protein transport
FGF54_RS07190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGF54_RS07195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGF54_RS07200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FGF54_RS07205	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FGF54_RS07210	COG1472	Belongs to the glycosyl hydrolase 3 family
FGF54_RS07220	COG0018	arginyl-trna synthetase
FGF54_RS07225	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FGF54_RS07260	COG0525	valine-tRNA ligase activity
FGF54_RS07270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FGF54_RS07310	COG0655	NAD(P)H dehydrogenase (quinone) activity
FGF54_RS07315	COG1546	Belongs to the CinA family
FGF54_RS07315	COG1058	Belongs to the CinA family
FGF54_RS07320	COG0589	response to stress
FGF54_RS07325	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FGF54_RS07340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGF54_RS07355	COG1914	H( )-stimulated, divalent metal cation uptake system
FGF54_RS07370	COG1132	(ABC) transporter
FGF54_RS07375	COG0628	permease
FGF54_RS07415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FGF54_RS07425	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FGF54_RS07435	COG0302	gtp cyclohydrolase
FGF54_RS07440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FGF54_RS07445	COG1752	Esterase of the alpha-beta hydrolase superfamily
FGF54_RS07455	COG0517	IMP dehydrogenase activity
FGF54_RS07455	COG0516	GMP reductase activity
FGF54_RS07490	COG1760	l-serine dehydratase
FGF54_RS07525	COG0583	DNA-binding transcription factor activity
FGF54_RS07540	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FGF54_RS07540	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FGF54_RS07550	COG0347	Belongs to the P(II) protein family
FGF54_RS07555	COG0174	glutamine synthetase
FGF54_RS07585	COG0697	spore germination
FGF54_RS07600	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FGF54_RS07610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FGF54_RS07620	COG3668	Plasmid stabilization system
FGF54_RS07625	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FGF54_RS07640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGF54_RS07645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGF54_RS07650	COG2186	Transcriptional regulator
FGF54_RS07660	COG1079	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS07665	COG4603	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS07670	COG3845	ABC transporter
FGF54_RS07675	COG1183	phosphatidylcholine synthase activity
FGF54_RS07680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGF54_RS07685	COG0679	Auxin Efflux Carrier
FGF54_RS07690	COG0785	Cytochrome C biogenesis protein
FGF54_RS07715	COG1278	Cold shock
FGF54_RS07785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGF54_RS07845	COG0577	efflux transmembrane transporter activity
FGF54_RS07845	COG1136	(ABC) transporter
FGF54_RS07850	COG0577	efflux transmembrane transporter activity
FGF54_RS07850	COG1136	(ABC) transporter
FGF54_RS07875	COG2151	metal-sulfur cluster biosynthetic enzyme
FGF54_RS07880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGF54_RS07885	COG0719	Fe-S assembly protein
FGF54_RS07890	COG0396	ATPase activity
FGF54_RS07895	COG0719	Fe-S assembly protein
FGF54_RS07900	COG1104	cysteine desulfurase activity
FGF54_RS07905	COG2945	thiolester hydrolase activity
FGF54_RS07915	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FGF54_RS07920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGF54_RS07930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FGF54_RS07935	COG2833	Protein of unknown function (DUF455)
FGF54_RS07940	COG0739	heme binding
FGF54_RS07945	COG0513	Belongs to the DEAD box helicase family
FGF54_RS07970	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGF54_RS07980	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FGF54_RS07985	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGF54_RS07990	COG0047	phosphoribosylformylglycinamidine synthase activity
FGF54_RS08005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGF54_RS08010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGF54_RS08035	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FGF54_RS08040	COG2814	Major facilitator Superfamily
FGF54_RS08045	COG0483	inositol monophosphate 1-phosphatase activity
FGF54_RS08050	COG0483	inositol monophosphate 1-phosphatase activity
FGF54_RS08055	COG0037	tRNA processing
FGF54_RS08060	COG2066	Belongs to the glutaminase family
FGF54_RS08065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FGF54_RS08070	COG0861	Integral membrane protein TerC family
FGF54_RS08090	COG1280	lysine exporter protein (LysE YggA)
FGF54_RS08095	COG3093	addiction module antidote protein HigA
FGF54_RS08115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FGF54_RS08120	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FGF54_RS08130	COG0538	isocitrate dehydrogenase activity
FGF54_RS08140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGF54_RS08145	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FGF54_RS08150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGF54_RS08155	COG2313	pseudouridylate synthase activity
FGF54_RS08170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGF54_RS08175	COG4215	(ABC) transporter
FGF54_RS08185	COG5425	PFAM Usg family protein
FGF54_RS08195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGF54_RS08200	COG1522	sequence-specific DNA binding
FGF54_RS08205	COG1573	uracil-dna glycosylase
FGF54_RS08215	COG2205	protein histidine kinase activity
FGF54_RS08215	COG2202	Pas domain
FGF54_RS08225	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FGF54_RS08230	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FGF54_RS08250	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGF54_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS08260	COG1129	ABC transporter
FGF54_RS08270	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS08280	COG3959	Transketolase, thiamine diphosphate binding domain
FGF54_RS08285	COG3958	Transketolase
FGF54_RS08290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FGF54_RS08295	COG2390	Transcriptional regulator
FGF54_RS08305	COG0842	Transport permease protein
FGF54_RS08310	COG1131	(ABC) transporter
FGF54_RS08315	COG0730	response to heat
FGF54_RS08315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGF54_RS08340	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FGF54_RS08345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGF54_RS08365	COG0129	dihydroxy-acid dehydratase activity
FGF54_RS08370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FGF54_RS08375	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FGF54_RS08385	COG0203	ribosomal protein L17
FGF54_RS08390	COG0202	RNA polymerase activity
FGF54_RS08395	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FGF54_RS08400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FGF54_RS08405	COG0563	adenylate kinase activity
FGF54_RS08410	COG0201	protein transport
FGF54_RS08415	COG0200	Binds to the 23S rRNA
FGF54_RS08420	COG1841	ribosomal large subunit assembly
FGF54_RS08425	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGF54_RS08430	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FGF54_RS08435	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FGF54_RS08440	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FGF54_RS08445	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGF54_RS08450	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGF54_RS08455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FGF54_RS08460	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FGF54_RS08465	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FGF54_RS08470	COG0255	Belongs to the universal ribosomal protein uL29 family
FGF54_RS08475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGF54_RS08480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FGF54_RS08485	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FGF54_RS08490	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FGF54_RS08495	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGF54_RS08500	COG0089	rRNA binding
FGF54_RS08505	COG0088	Forms part of the polypeptide exit tunnel
FGF54_RS08510	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FGF54_RS08515	COG0051	transcription antitermination factor activity, RNA binding
FGF54_RS08520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGF54_RS08525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGF54_RS08530	COG0049	tRNA binding
FGF54_RS08535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FGF54_RS08555	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGF54_RS08560	COG0085	RNA polymerase activity
FGF54_RS08565	COG0222	ribosome binding
FGF54_RS08570	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FGF54_RS08575	COG0081	regulation of translation
FGF54_RS08580	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FGF54_RS08590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FGF54_RS08605	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGF54_RS08610	COG0861	Integral membrane protein TerC family
FGF54_RS08625	COG3895	Periplasmic Protein
FGF54_RS08660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGF54_RS08665	COG1607	acyl-coa hydrolase
FGF54_RS08685	COG2910	NAD(P)H-binding
FGF54_RS08690	COG1733	regulation of RNA biosynthetic process
FGF54_RS08695	COG0456	acetyltransferase
FGF54_RS08695	COG0454	-acetyltransferase
FGF54_RS08705	COG0556	nucleotide-excision repair
FGF54_RS08730	COG0484	heat shock protein binding
FGF54_RS08770	COG1840	ABC-type Fe3 transport system, periplasmic component
FGF54_RS08780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGF54_RS08795	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FGF54_RS08810	COG2207	Transcriptional regulator
FGF54_RS08815	COG1064	alcohol dehydrogenase
FGF54_RS08820	COG1252	NADH dehydrogenase
FGF54_RS08825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FGF54_RS08835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGF54_RS08840	COG1090	epimerase
FGF54_RS08880	COG0656	L-ascorbic acid biosynthetic process
FGF54_RS08895	COG0440	acetolactate synthase activity
FGF54_RS08900	COG0028	Belongs to the TPP enzyme family
FGF54_RS08910	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGF54_RS08915	COG3830	Belongs to the UPF0237 family
FGF54_RS08915	COG0560	Phosphoserine phosphatase
FGF54_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS08935	COG0330	HflC and HflK could
FGF54_RS08940	COG0330	HflC and HflK could
FGF54_RS08950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FGF54_RS08990	COG0277	FAD linked oxidase domain protein
FGF54_RS08995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGF54_RS09035	COG1335	isochorismatase
FGF54_RS09065	COG2264	protein methyltransferase activity
FGF54_RS09070	COG1999	signal sequence binding
FGF54_RS09080	COG0835	chemotaxis
FGF54_RS09090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FGF54_RS09095	COG0583	DNA-binding transcription factor activity
FGF54_RS09105	COG1247	-acetyltransferase
FGF54_RS09115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGF54_RS09120	COG0497	DNA recombination
FGF54_RS09125	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGF54_RS09135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FGF54_RS09140	COG0849	cell division
FGF54_RS09145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FGF54_RS09150	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGF54_RS09155	COG0477	Major facilitator Superfamily
FGF54_RS09160	COG5001	Diguanylate cyclase
FGF54_RS09160	COG3300	MHYT domain
FGF54_RS09165	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FGF54_RS09170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGF54_RS09175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGF54_RS09185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGF54_RS09190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGF54_RS09200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGF54_RS09215	COG0275	rRNA processing
FGF54_RS09220	COG2001	Belongs to the MraZ family
FGF54_RS09255	COG3023	N-Acetylmuramoyl-L-alanine amidase
FGF54_RS09260	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FGF54_RS09285	COG4106	trans-aconitate 2-methyltransferase activity
FGF54_RS09305	COG2226	methyltransferase
FGF54_RS09315	COG2267	carboxylic ester hydrolase activity
FGF54_RS09320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FGF54_RS09350	COG1376	ErfK ybiS ycfS ynhG family protein
FGF54_RS09355	COG2814	Major facilitator Superfamily
FGF54_RS09380	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS09385	COG0174	glutamine synthetase
FGF54_RS09390	COG0531	amino acid
FGF54_RS09400	COG1737	Transcriptional regulator
FGF54_RS09410	COG1840	ABC-type Fe3 transport system, periplasmic component
FGF54_RS09425	COG3842	ATPase activity
FGF54_RS09485	COG2968	Membrane
FGF54_RS09495	COG0432	Pfam Uncharacterised protein family UPF0047
FGF54_RS09510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGF54_RS09515	COG0358	DNA primase activity
FGF54_RS09535	COG0505	Belongs to the CarA family
FGF54_RS09540	COG0534	Mate efflux family protein
FGF54_RS09555	COG2321	neutral zinc metallopeptidase
FGF54_RS09570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGF54_RS09580	COG3706	GGDEF domain
FGF54_RS09595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGF54_RS09605	COG1522	sequence-specific DNA binding
FGF54_RS09610	COG0492	ferredoxin-NADP+ reductase activity
FGF54_RS09615	COG0583	DNA-binding transcription factor activity
FGF54_RS09625	COG1902	pentaerythritol trinitrate reductase activity
FGF54_RS09655	COG0387	Pfam Sodium calcium exchanger
FGF54_RS09660	COG0436	Aminotransferase
FGF54_RS09680	COG1278	Cold shock
FGF54_RS09685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGF54_RS09700	COG1846	Transcriptional regulator
FGF54_RS09705	COG0745	RESPONSE REGULATOR receiver
FGF54_RS09710	COG2205	protein histidine kinase activity
FGF54_RS09715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGF54_RS09740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FGF54_RS09750	COG1496	oxidoreductase activity
FGF54_RS09755	COG0006	proline dipeptidase activity
FGF54_RS09765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGF54_RS09795	COG0840	transmembrane signaling receptor activity
FGF54_RS09800	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS09805	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FGF54_RS09810	COG5001	Diguanylate cyclase
FGF54_RS09810	COG3300	MHYT domain
FGF54_RS09815	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FGF54_RS09820	COG5001	Diguanylate cyclase
FGF54_RS09830	COG0193	aminoacyl-tRNA hydrolase activity
FGF54_RS09840	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FGF54_RS09860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGF54_RS09870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FGF54_RS09870	COG2857	Cytochrome c1
FGF54_RS09890	COG1132	(ABC) transporter
FGF54_RS09895	COG1132	(ABC) transporter
FGF54_RS09900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FGF54_RS09905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FGF54_RS09920	COG0408	coproporphyrinogen oxidase activity
FGF54_RS09935	COG0617	tRNA 3'-terminal CCA addition
FGF54_RS09950	COG0714	Associated with various cellular activities
FGF54_RS09970	COG0454	-acetyltransferase
FGF54_RS09990	COG0477	Major facilitator Superfamily
FGF54_RS10000	COG0435	Glutathione S-transferase
FGF54_RS10005	COG0494	nUDIX hydrolase
FGF54_RS10020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGF54_RS10035	COG3135	benzoate transporter
FGF54_RS10060	COG0740	serine-type endopeptidase activity
FGF54_RS10075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FGF54_RS10080	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FGF54_RS10110	COG4175	Glycine betaine
FGF54_RS10125	COG1435	thymidine kinase activity
FGF54_RS10145	COG2862	Uncharacterized protein family, UPF0114
FGF54_RS10150	COG1629	transport
FGF54_RS10150	COG4771	TonB-dependent receptor
FGF54_RS10160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGF54_RS10160	COG0512	Glutamine amidotransferase of anthranilate synthase
FGF54_RS10175	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FGF54_RS10190	COG0366	Alpha amylase catalytic
FGF54_RS10195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGF54_RS10210	COG1160	GTP binding
FGF54_RS10230	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FGF54_RS10240	COG0024	Methionine aminopeptidase
FGF54_RS10255	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS10265	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGF54_RS10275	COG0583	DNA-binding transcription factor activity
FGF54_RS10290	COG0402	S-adenosylhomocysteine deaminase activity
FGF54_RS10305	COG1304	FMN binding
FGF54_RS10315	COG1309	transcriptional regulator
FGF54_RS10320	COG1686	Belongs to the peptidase S11 family
FGF54_RS10325	COG4115	mRNA cleavage
FGF54_RS10340	COG2351	hydroxyisourate hydrolase activity
FGF54_RS10345	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FGF54_RS10370	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FGF54_RS10380	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FGF54_RS10380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS10385	COG2205	protein histidine kinase activity
FGF54_RS10385	COG5002	protein histidine kinase activity
FGF54_RS10385	COG0784	Response regulator, receiver
FGF54_RS10390	COG0513	Belongs to the DEAD box helicase family
FGF54_RS10400	COG2259	Doxx family
FGF54_RS10405	COG1376	ErfK ybiS ycfS ynhG family protein
FGF54_RS10415	COG2308	Evidence 4 Homologs of previously reported genes of
FGF54_RS10425	COG1305	Transglutaminase-like
FGF54_RS10450	COG4214	carbohydrate transport
FGF54_RS10460	COG4213	ABC transporter substrate-binding protein
FGF54_RS10505	COG0300	oxidoreductase activity
FGF54_RS10520	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS10540	COG1999	signal sequence binding
FGF54_RS10565	COG1027	Aspartate ammonia-lyase
FGF54_RS10575	COG0626	cystathionine gamma-synthase activity
FGF54_RS10580	COG0583	DNA-binding transcription factor activity
FGF54_RS10590	COG0765	amino acid transport
FGF54_RS10595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGF54_RS10620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS10660	COG0596	Alpha beta hydrolase
FGF54_RS10670	COG0840	transmembrane signaling receptor activity
FGF54_RS10685	COG0646	methionine synthase
FGF54_RS10685	COG1410	methionine synthase
FGF54_RS10730	COG1215	transferase activity, transferring glycosyl groups
FGF54_RS10765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGF54_RS10780	COG2346	COG2346, Truncated hemoglobins
FGF54_RS10800	COG1309	transcriptional regulator
FGF54_RS10815	COG0494	nUDIX hydrolase
FGF54_RS10830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS10835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS10870	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FGF54_RS10875	COG0830	nickel cation binding
FGF54_RS10880	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FGF54_RS10895	COG0804	urea catabolic process
FGF54_RS10900	COG1442	glycosyl transferase family 8
FGF54_RS10905	COG3755	Protein conserved in bacteria
FGF54_RS10915	COG0832	Belongs to the urease beta subunit family
FGF54_RS10920	COG3813	Protein conserved in bacteria
FGF54_RS10925	COG0831	urea catabolic process
FGF54_RS10930	COG0829	nickel cation binding
FGF54_RS10960	COG0559	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS10975	COG0174	glutamine synthetase
FGF54_RS10980	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS10985	COG5002	protein histidine kinase activity
FGF54_RS10985	COG2198	Histidine kinase
FGF54_RS10985	COG0784	Response regulator, receiver
FGF54_RS11040	COG1218	3'(2'),5'-bisphosphate nucleotidase
FGF54_RS11125	COG0564	pseudouridine synthase activity
FGF54_RS11135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGF54_RS11150	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FGF54_RS11185	COG0346	lactoylglutathione lyase activity
FGF54_RS11195	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FGF54_RS11205	COG2832	Protein of unknown function (DUF454)
FGF54_RS11210	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FGF54_RS11215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGF54_RS11220	COG4558	Periplasmic binding protein
FGF54_RS11230	COG3721	Heme iron utilization protein
FGF54_RS11250	COG3657	addiction module killer protein
FGF54_RS11260	COG2205	protein histidine kinase activity
FGF54_RS11305	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGF54_RS11310	COG4605	iron ion homeostasis
FGF54_RS11315	COG4604	ABC transporter, ATP-binding protein
FGF54_RS11320	COG0783	Belongs to the Dps family
FGF54_RS11335	COG0656	L-ascorbic acid biosynthetic process
FGF54_RS11340	COG2814	Major facilitator Superfamily
FGF54_RS11350	COG0583	DNA-binding transcription factor activity
FGF54_RS11355	COG0657	acetylesterase activity
FGF54_RS11360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGF54_RS11380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGF54_RS11385	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FGF54_RS11390	COG0288	reversible hydration of carbon dioxide
FGF54_RS11400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGF54_RS11420	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FGF54_RS11425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FGF54_RS11430	COG0778	Nitroreductase
FGF54_RS11435	COG2267	carboxylic ester hydrolase activity
FGF54_RS11440	COG0251	oxidation-reduction process
FGF54_RS11445	COG1335	isochorismatase
FGF54_RS11450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS11460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGF54_RS11475	COG1175	transmembrane transport
FGF54_RS11480	COG0395	ABC-type sugar transport system, permease component
FGF54_RS11485	COG3842	ATPase activity
FGF54_RS11490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGF54_RS11500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGF54_RS11505	COG0583	DNA-binding transcription factor activity
FGF54_RS11515	COG4608	Belongs to the ABC transporter superfamily
FGF54_RS11520	COG0444	Belongs to the ABC transporter superfamily
FGF54_RS11525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS11530	COG0601	transmembrane transport
FGF54_RS11535	COG4166	transmembrane transport
FGF54_RS11550	COG0392	lysyltransferase activity
FGF54_RS11550	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FGF54_RS11585	COG2159	amidohydrolase
FGF54_RS11590	COG1960	acyl-CoA dehydrogenase activity
FGF54_RS11620	COG0745	RESPONSE REGULATOR receiver
FGF54_RS11630	COG1902	pentaerythritol trinitrate reductase activity
FGF54_RS11630	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGF54_RS11635	COG3842	ATPase activity
FGF54_RS11645	COG1840	ABC-type Fe3 transport system, periplasmic component
FGF54_RS11650	COG1840	ABC-type Fe3 transport system, periplasmic component
FGF54_RS11655	COG0745	RESPONSE REGULATOR receiver
FGF54_RS11665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FGF54_RS11670	COG0583	DNA-binding transcription factor activity
FGF54_RS11675	COG1376	ErfK ybiS ycfS ynhG family protein
FGF54_RS11680	COG0642	Histidine kinase
FGF54_RS11695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGF54_RS11695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FGF54_RS11705	COG2801	Transposase and inactivated derivatives
FGF54_RS11710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGF54_RS11730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGF54_RS11765	COG4208	sulfate ABC transporter
FGF54_RS11770	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGF54_RS11780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS11790	COG3842	ATPase activity
FGF54_RS11795	COG0583	DNA-binding transcription factor activity
FGF54_RS11830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGF54_RS11840	COG1454	alcohol dehydrogenase
FGF54_RS11870	COG0596	Alpha beta hydrolase
FGF54_RS11915	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FGF54_RS11925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGF54_RS11930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGF54_RS11940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FGF54_RS11945	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FGF54_RS11950	COG1509	lysine 2,3-aminomutase activity
FGF54_RS11965	COG0583	DNA-binding transcription factor activity
FGF54_RS11970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS11980	COG0725	ABC transporter, periplasmic molybdate-binding protein
FGF54_RS11985	COG4149	molybdate abc transporter
FGF54_RS11990	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FGF54_RS12005	COG2022	thiamine diphosphate biosynthetic process
FGF54_RS12020	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FGF54_RS12025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGF54_RS12035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGF54_RS12060	COG1132	(ABC) transporter
FGF54_RS12065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGF54_RS12090	COG0438	transferase activity, transferring glycosyl groups
FGF54_RS12110	COG4166	transmembrane transport
FGF54_RS12115	COG0601	transmembrane transport
FGF54_RS12120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS12130	COG0438	transferase activity, transferring glycosyl groups
FGF54_RS12135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGF54_RS12140	COG3142	Participates in the control of copper homeostasis
FGF54_RS12145	COG2814	Major facilitator Superfamily
FGF54_RS12160	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS12165	COG1737	Transcriptional regulator
FGF54_RS12175	COG3842	ATPase activity
FGF54_RS12185	COG0395	ABC-type sugar transport system, permease component
FGF54_RS12190	COG1175	transmembrane transport
FGF54_RS12205	COG2188	Transcriptional regulator
FGF54_RS12210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGF54_RS12215	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FGF54_RS12220	COG1940	carbohydrate kinase activity
FGF54_RS12230	COG0671	phosphoesterase, PA-phosphatase related
FGF54_RS12235	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FGF54_RS12240	COG0156	8-amino-7-oxononanoate synthase activity
FGF54_RS12250	COG0729	surface antigen
FGF54_RS12260	COG0835	chemotaxis
FGF54_RS12270	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FGF54_RS12275	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FGF54_RS12280	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGF54_RS12285	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGF54_RS12290	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGF54_RS12295	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGF54_RS12310	COG4974	Belongs to the 'phage' integrase family
FGF54_RS12335	COG1280	lysine exporter protein (LysE YggA)
FGF54_RS12345	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGF54_RS12350	COG0567	Dehydrogenase, E1 component
FGF54_RS12355	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FGF54_RS12360	COG0045	succinate-CoA ligase (ADP-forming) activity
FGF54_RS12365	COG0039	L-malate dehydrogenase activity
FGF54_RS12370	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FGF54_RS12405	COG2264	protein methyltransferase activity
FGF54_RS12420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FGF54_RS12425	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGF54_RS12430	COG0181	hydroxymethylbilane synthase activity
FGF54_RS12465	COG1872	DUF167
FGF54_RS12470	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FGF54_RS12480	COG1217	gtp-binding protein TYPA
FGF54_RS12485	COG0339	signal peptide processing
FGF54_RS12495	COG1846	Transcriptional regulator
FGF54_RS12505	COG0137	argininosuccinate synthase activity
FGF54_RS12515	COG1280	lysine exporter protein (LysE YggA)
FGF54_RS12520	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FGF54_RS12525	COG4120	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS12535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FGF54_RS12550	COG2154	pterin-4-alpha-carbinolamine dehydratase
FGF54_RS12555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGF54_RS12560	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FGF54_RS12570	COG4181	ATPase activity
FGF54_RS12580	COG0670	Belongs to the BI1 family
FGF54_RS12595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FGF54_RS12600	COG4133	protoheme IX ABC transporter activity
FGF54_RS12610	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGF54_RS12615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGF54_RS12640	COG2917	probably involved in intracellular septation
FGF54_RS12645	COG0552	protein localization to endoplasmic reticulum
FGF54_RS12650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGF54_RS12655	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FGF54_RS12670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FGF54_RS12675	COG0287	Prephenate dehydrogenase
FGF54_RS12675	COG1605	Chorismate mutase
FGF54_RS12680	COG0228	four-way junction DNA binding
FGF54_RS12685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FGF54_RS12690	COG0336	Belongs to the RNA methyltransferase TrmD family
FGF54_RS12700	COG0335	large ribosomal subunit rRNA binding
FGF54_RS12705	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FGF54_RS12710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGF54_RS12730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FGF54_RS12755	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FGF54_RS12775	COG0488	(ABC) transporter
FGF54_RS12785	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FGF54_RS12795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGF54_RS12800	COG0142	geranyltranstransferase activity
FGF54_RS12805	COG2885	chlorophyll binding
FGF54_RS12810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FGF54_RS12815	COG2223	nitrite transmembrane transporter activity
FGF54_RS12820	COG1349	DNA-binding transcription factor activity
FGF54_RS12825	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FGF54_RS12830	COG2197	response regulator
FGF54_RS12835	COG1132	(ABC) transporter
FGF54_RS12845	COG3459	Glycosyltransferase 36 associated
FGF54_RS12850	COG1473	amidohydrolase
FGF54_RS12860	COG0579	oxidoreductase
FGF54_RS12870	COG0129	dihydroxy-acid dehydratase activity
FGF54_RS12875	COG2084	Dehydrogenase
FGF54_RS12880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGF54_RS12885	COG0277	FAD linked oxidase domain protein
FGF54_RS12890	COG2186	Transcriptional regulator
FGF54_RS12900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FGF54_RS12905	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FGF54_RS12910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FGF54_RS12915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGF54_RS12925	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FGF54_RS12930	COG0495	leucyl-tRNA aminoacylation
FGF54_RS12945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FGF54_RS12950	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGF54_RS12965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGF54_RS12970	COG1946	Acyl-CoA thioesterase
FGF54_RS12975	COG0347	Belongs to the P(II) protein family
FGF54_RS12980	COG0004	ammonium transporteR
FGF54_RS12985	COG1674	ftsk spoiiie
FGF54_RS12990	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FGF54_RS13005	COG0745	RESPONSE REGULATOR receiver
FGF54_RS13015	COG1329	Transcriptional regulator
FGF54_RS13025	COG2270	Major facilitator Superfamily
FGF54_RS13035	COG0183	Belongs to the thiolase family
FGF54_RS13040	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS13055	COG0494	nUDIX hydrolase
FGF54_RS13060	COG2861	carbohydrate metabolic process
FGF54_RS13065	COG0793	Belongs to the peptidase S41A family
FGF54_RS13075	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FGF54_RS13085	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FGF54_RS13090	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FGF54_RS13095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FGF54_RS13100	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGF54_RS13115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FGF54_RS13120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FGF54_RS13135	COG2301	Belongs to the HpcH HpaI aldolase family
FGF54_RS13145	COG0066	3-isopropylmalate dehydratase activity
FGF54_RS13150	COG0473	3-isopropylmalate dehydrogenase activity
FGF54_RS13155	COG1858	cytochrome C peroxidase
FGF54_RS13160	COG1797	cobyrinic acid a,c-diamide synthase activity
FGF54_RS13170	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FGF54_RS13235	COG1492	cobalamin metabolic process
FGF54_RS13250	COG4948	Mandelate Racemase Muconate Lactonizing
FGF54_RS13255	COG3254	rhamnose metabolic process
FGF54_RS13260	COG0246	Mannitol dehydrogenase
FGF54_RS13265	COG1063	alcohol dehydrogenase
FGF54_RS13285	COG4214	carbohydrate transport
FGF54_RS13290	COG1129	ABC transporter
FGF54_RS13295	COG2186	Transcriptional regulator
FGF54_RS13300	COG2721	sulfolactate sulfo-lyase activity
FGF54_RS13305	COG0138	bifunctional purine biosynthesis protein purh
FGF54_RS13315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGF54_RS13315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGF54_RS13320	COG0501	Belongs to the peptidase M48B family
FGF54_RS13340	COG0357	Ribosomal RNA small subunit methyltransferase G
FGF54_RS13345	COG0445	tRNA wobble uridine modification
FGF54_RS13350	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FGF54_RS13355	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FGF54_RS13360	COG1981	membrane
FGF54_RS13365	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FGF54_RS13370	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FGF54_RS13375	COG0424	maF-like protein
FGF54_RS13380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGF54_RS13385	COG0237	dephospho-CoA kinase activity
FGF54_RS13395	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FGF54_RS13400	COG3030	protein affecting phage T7 exclusion by the F plasmid
FGF54_RS13410	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FGF54_RS13435	COG0179	Fumarylacetoacetate (FAA) hydrolase
FGF54_RS13450	COG0135	phosphoribosylanthranilate isomerase activity
FGF54_RS13455	COG0133	tryptophan synthase activity
FGF54_RS13460	COG0159	tryptophan synthase activity
FGF54_RS13465	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FGF54_RS13470	COG0285	dihydrofolate synthase activity
FGF54_RS13480	COG1074	ATP-dependent DNA helicase activity
FGF54_RS13490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FGF54_RS13500	COG2205	protein histidine kinase activity
FGF54_RS13510	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FGF54_RS13515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGF54_RS13520	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGF54_RS13520	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGF54_RS13525	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FGF54_RS13530	COG0642	Histidine kinase
FGF54_RS13535	COG0745	RESPONSE REGULATOR receiver
FGF54_RS13540	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FGF54_RS13550	COG1072	(Pantothenic acid kinase))
FGF54_RS13555	COG0140	phosphoribosyl-ATP diphosphatase activity
FGF54_RS13560	COG0107	imidazoleglycerol-phosphate synthase activity
FGF54_RS13565	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FGF54_RS13570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FGF54_RS13580	COG0131	Imidazoleglycerol-phosphate dehydratase
FGF54_RS13585	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FGF54_RS13590	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FGF54_RS13600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FGF54_RS13615	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FGF54_RS13625	COG1643	Atp-dependent helicase
FGF54_RS13675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FGF54_RS13690	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FGF54_RS13700	COG2986	histidine ammonia-lyase
FGF54_RS13705	COG0514	ATP-dependent DNA helicase (RecQ)
FGF54_RS13730	COG1072	(Pantothenic acid kinase))
FGF54_RS13740	COG1780	Probably involved in ribonucleotide reductase function
FGF54_RS13760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FGF54_RS13790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGF54_RS13805	COG1185	polyribonucleotide nucleotidyltransferase activity
FGF54_RS13810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FGF54_RS13815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FGF54_RS13820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FGF54_RS13825	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FGF54_RS13825	COG3064	Membrane
FGF54_RS13840	COG0779	Required for maturation of 30S ribosomal subunits
FGF54_RS13845	COG2814	Major facilitator Superfamily
FGF54_RS13850	COG2951	lytic endotransglycosylase activity
FGF54_RS13855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FGF54_RS13865	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FGF54_RS13870	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FGF54_RS13885	COG2816	NAD+ diphosphatase activity
FGF54_RS13890	COG0077	Prephenate dehydratase
FGF54_RS13890	COG1605	Chorismate mutase
FGF54_RS13895	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FGF54_RS13900	COG3474	cytochrome
FGF54_RS13910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FGF54_RS13915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FGF54_RS13925	COG1278	Cold shock
FGF54_RS13930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGF54_RS13940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGF54_RS13940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGF54_RS13945	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FGF54_RS13980	COG2900	Belongs to the SlyX family
FGF54_RS13990	COG0484	heat shock protein binding
FGF54_RS13995	COG0443	Heat shock 70 kDa protein
FGF54_RS14010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGF54_RS14015	COG1744	ABC transporter substrate-binding protein PnrA-like
FGF54_RS14020	COG3845	ABC transporter
FGF54_RS14025	COG1079	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS14030	COG1079	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS14035	COG0295	cytidine deaminase activity
FGF54_RS14040	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FGF54_RS14045	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FGF54_RS14050	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FGF54_RS14060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FGF54_RS14065	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FGF54_RS14070	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FGF54_RS14080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FGF54_RS14085	COG1845	cytochrome c oxidase, subunit III
FGF54_RS14090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FGF54_RS14100	COG0477	Major facilitator Superfamily
FGF54_RS14110	COG0069	glutamate synthase activity
FGF54_RS14110	COG0070	glutamate synthase
FGF54_RS14110	COG0067	glutamate synthase
FGF54_RS14115	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FGF54_RS14130	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGF54_RS14140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGF54_RS14175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS14195	COG0848	biopolymer transport protein
FGF54_RS14205	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FGF54_RS14220	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FGF54_RS14225	COG3454	Phosphonate metabolism
FGF54_RS14230	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FGF54_RS14235	COG3639	organic phosphonate transmembrane transporter activity
FGF54_RS14240	COG3639	organic phosphonate transmembrane transporter activity
FGF54_RS14245	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FGF54_RS14250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FGF54_RS14260	COG4778	phosphonate C-P lyase system protein PhnL
FGF54_RS14265	COG4107	phosphonate C-P lyase system protein PhnK
FGF54_RS14270	COG3627	carbon phosphorus lyase activity
FGF54_RS14275	COG3626	phosphonate metabolism
FGF54_RS14280	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FGF54_RS14285	COG3624	Phosphonate C-P lyase system protein PhnG
FGF54_RS14290	COG2188	Transcriptional regulator
FGF54_RS14295	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FGF54_RS14300	COG0837	glucose binding
FGF54_RS14305	COG1803	Methylglyoxal synthase
FGF54_RS14310	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FGF54_RS14315	COG4166	transmembrane transport
FGF54_RS14320	COG4174	ABC transporter (Permease)
FGF54_RS14325	COG4239	(ABC) transporter, permease
FGF54_RS14330	COG4172	Belongs to the ABC transporter superfamily
FGF54_RS14335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS14340	COG0174	glutamine synthetase
FGF54_RS14345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS14350	COG3265	gluconokinase activity
FGF54_RS14355	COG1174	glycine betaine transport
FGF54_RS14360	COG1125	glycine betaine transport
FGF54_RS14365	COG1174	glycine betaine transport
FGF54_RS14370	COG1732	Glycine betaine
FGF54_RS14380	COG1959	2 iron, 2 sulfur cluster binding
FGF54_RS14385	COG1840	ABC-type Fe3 transport system, periplasmic component
FGF54_RS14395	COG4269	membrane
FGF54_RS14410	COG0697	spore germination
FGF54_RS14425	COG0791	NLP P60 protein
FGF54_RS14435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FGF54_RS14440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FGF54_RS14475	COG4964	Belongs to the GSP D family
FGF54_RS14525	COG3422	double-strand break repair
FGF54_RS14530	COG3757	hydrolase, family 25
FGF54_RS14535	COG0697	spore germination
FGF54_RS14540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGF54_RS14570	COG0481	GTPase activity
FGF54_RS14575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGF54_RS14590	COG1396	sequence-specific DNA binding
FGF54_RS14605	COG2169	Transcriptional regulator
FGF54_RS14605	COG1917	Cupin 2, conserved barrel domain protein
FGF54_RS14610	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FGF54_RS14635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FGF54_RS14640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FGF54_RS14645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FGF54_RS14655	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FGF54_RS14660	COG0072	phenylalanine-tRNA ligase activity
FGF54_RS14660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGF54_RS14665	COG0667	Aldo Keto reductase
FGF54_RS14685	COG4977	sequence-specific DNA binding
FGF54_RS14710	COG1570	exodeoxyribonuclease VII activity
FGF54_RS14715	COG4948	Mandelate Racemase Muconate Lactonizing
FGF54_RS14725	COG1846	Transcriptional regulator
FGF54_RS14730	COG0697	spore germination
FGF54_RS14735	COG2309	aminopeptidase activity
FGF54_RS14745	COG1393	Belongs to the ArsC family
FGF54_RS14775	COG0300	oxidoreductase activity
FGF54_RS14780	COG0500	methyltransferase
FGF54_RS14790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FGF54_RS14790	COG0519	Catalyzes the synthesis of GMP from XMP
FGF54_RS14805	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FGF54_RS14835	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FGF54_RS14845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FGF54_RS14855	COG1968	undecaprenyl-diphosphatase activity
FGF54_RS14880	COG0284	orotidine-5'-phosphate decarboxylase activity
FGF54_RS14890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGF54_RS14900	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FGF54_RS14905	COG0792	nuclease activity
FGF54_RS14920	COG1175	transmembrane transport
FGF54_RS14930	COG3842	ATPase activity
FGF54_RS14940	COG0189	ligase activity
FGF54_RS14945	COG0606	chelatase, subunit chli
FGF54_RS14950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGF54_RS14955	COG1280	lysine exporter protein (LysE YggA)
FGF54_RS14960	COG0756	dUTP diphosphatase activity
FGF54_RS14965	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FGF54_RS14970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FGF54_RS14985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FGF54_RS14990	COG2226	methyltransferase
FGF54_RS14995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGF54_RS15000	COG1024	Enoyl-CoA hydratase
FGF54_RS15005	COG0268	Binds directly to 16S ribosomal RNA
FGF54_RS15090	COG0640	Transcriptional regulator
FGF54_RS15145	COG0395	ABC-type sugar transport system, permease component
FGF54_RS15150	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGF54_RS15160	COG3842	ATPase activity
FGF54_RS15200	COG1653	transport
FGF54_RS15215	COG3842	ATPase activity
FGF54_RS15235	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGF54_RS15240	COG3842	ATPase activity
FGF54_RS15260	COG2072	flavoprotein involved in K transport
FGF54_RS15270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGF54_RS15275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS15280	COG1116	anion transmembrane transporter activity
FGF54_RS15290	COG2271	Major facilitator Superfamily
FGF54_RS15295	COG1473	amidohydrolase
FGF54_RS15300	COG0395	ABC-type sugar transport system, permease component
FGF54_RS15305	COG1175	transmembrane transport
FGF54_RS15335	COG1609	Transcriptional regulator
FGF54_RS15350	COG1082	Xylose isomerase domain protein TIM barrel
FGF54_RS15365	COG3842	ATPase activity
FGF54_RS15370	COG0395	ABC-type sugar transport system, permease component
FGF54_RS15375	COG1175	transmembrane transport
FGF54_RS15380	COG1653	transport
FGF54_RS15385	COG1309	transcriptional regulator
FGF54_RS15390	COG0673	inositol 2-dehydrogenase activity
FGF54_RS15405	COG0673	inositol 2-dehydrogenase activity
FGF54_RS15410	COG1278	Cold shock
FGF54_RS15435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGF54_RS15440	COG1136	(ABC) transporter
FGF54_RS15440	COG0577	efflux transmembrane transporter activity
FGF54_RS15445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGF54_RS15470	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FGF54_RS15485	COG3842	ATPase activity
FGF54_RS15490	COG0395	ABC-type sugar transport system, permease component
FGF54_RS15495	COG1175	transmembrane transport
FGF54_RS15505	COG3618	amidohydrolase
FGF54_RS15510	COG4948	Mandelate Racemase Muconate Lactonizing
FGF54_RS15515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGF54_RS15520	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS15525	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FGF54_RS15530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGF54_RS15535	COG2186	Transcriptional regulator
FGF54_RS15585	COG4977	sequence-specific DNA binding
FGF54_RS15590	COG2223	nitrite transmembrane transporter activity
FGF54_RS15595	COG0583	DNA-binding transcription factor activity
FGF54_RS15600	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FGF54_RS15610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FGF54_RS15615	COG2084	Dehydrogenase
FGF54_RS15630	COG1609	Transcriptional regulator
FGF54_RS15635	COG1063	alcohol dehydrogenase
FGF54_RS15640	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS15650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGF54_RS15655	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FGF54_RS15660	COG1175	transmembrane transport
FGF54_RS15665	COG0395	ABC-type sugar transport system, permease component
FGF54_RS15680	COG0395	ABC-type sugar transport system, permease component
FGF54_RS15685	COG1175	transmembrane transport
FGF54_RS15690	COG2182	Extracellular solute-binding protein
FGF54_RS15695	COG0626	cystathionine gamma-synthase activity
FGF54_RS15710	COG0803	Belongs to the bacterial solute-binding protein 9 family
FGF54_RS15720	COG1121	(ABC) transporter
FGF54_RS15725	COG0523	cobalamin synthesis protein
FGF54_RS15740	COG0523	cobalamin synthesis protein
FGF54_RS15745	COG1653	transport
FGF54_RS15750	COG1175	transmembrane transport
FGF54_RS15755	COG0395	ABC-type sugar transport system, permease component
FGF54_RS15760	COG3842	ATPase activity
FGF54_RS15770	COG3047	cAMP biosynthetic process
FGF54_RS15795	COG0583	DNA-binding transcription factor activity
FGF54_RS15800	COG1879	ABC-type sugar transport system periplasmic component
FGF54_RS15805	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS15810	COG1129	ABC transporter
FGF54_RS15820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGF54_RS15825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGF54_RS15830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FGF54_RS15845	COG3257	ureidoglycine aminohydrolase activity
FGF54_RS15855	COG5001	Diguanylate cyclase
FGF54_RS15860	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FGF54_RS15870	COG0747	negative chemotaxis
FGF54_RS15875	COG0601	transmembrane transport
FGF54_RS15880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS15890	COG4608	Belongs to the ABC transporter superfamily
FGF54_RS15895	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FGF54_RS15910	COG0346	lactoylglutathione lyase activity
FGF54_RS15920	COG0129	dihydroxy-acid dehydratase activity
FGF54_RS15925	COG1879	ABC-type sugar transport system periplasmic component
FGF54_RS15930	COG1129	ABC transporter
FGF54_RS15935	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS15940	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS15945	COG2186	Transcriptional regulator
FGF54_RS15965	COG0587	DNA-directed DNA polymerase activity
FGF54_RS15995	COG0673	inositol 2-dehydrogenase activity
FGF54_RS16005	COG3842	ATPase activity
FGF54_RS16010	COG0395	ABC-type sugar transport system, permease component
FGF54_RS16015	COG1175	transmembrane transport
FGF54_RS16020	COG1653	transport
FGF54_RS16030	COG0673	inositol 2-dehydrogenase activity
FGF54_RS16045	COG5001	Diguanylate cyclase
FGF54_RS16060	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FGF54_RS16065	COG2894	cell division
FGF54_RS16070	COG0850	regulation of cytokinetic process
FGF54_RS16075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGF54_RS16080	COG2186	Transcriptional regulator
FGF54_RS16085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FGF54_RS16095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FGF54_RS16100	COG1063	alcohol dehydrogenase
FGF54_RS16105	COG1312	Catalyzes the dehydration of D-mannonate
FGF54_RS16125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FGF54_RS16130	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FGF54_RS16130	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FGF54_RS16135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS16150	COG0625	glutathione transferase activity
FGF54_RS16160	COG1921	L-seryl-tRNASec selenium transferase activity
FGF54_RS16175	COG3964	amidohydrolase
FGF54_RS16185	COG0601	transmembrane transport
FGF54_RS16190	COG0747	negative chemotaxis
FGF54_RS16200	COG0438	transferase activity, transferring glycosyl groups
FGF54_RS16230	COG3210	domain, Protein
FGF54_RS16230	COG2911	Protein conserved in bacteria
FGF54_RS16240	COG4989	oxidoreductase activity
FGF54_RS16255	COG3842	ATPase activity
FGF54_RS16260	COG1653	transport
FGF54_RS16265	COG1175	transmembrane transport
FGF54_RS16270	COG0395	ABC-type sugar transport system, permease component
FGF54_RS16275	COG1501	Belongs to the glycosyl hydrolase 31 family
FGF54_RS16285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS16290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGF54_RS16295	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FGF54_RS16300	COG0352	thiamine-phosphate diphosphorylase activity
FGF54_RS16305	COG0351	phosphomethylpyrimidine kinase
FGF54_RS16315	COG1522	sequence-specific DNA binding
FGF54_RS16320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGF54_RS16325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS16340	COG2204	response regulator
FGF54_RS16345	COG4191	Histidine kinase
FGF54_RS16350	COG1301	dicarboxylic acid transport
FGF54_RS16360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FGF54_RS16365	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS16375	COG1473	amidohydrolase
FGF54_RS16395	COG1215	transferase activity, transferring glycosyl groups
FGF54_RS16405	COG2942	2-epimerase
FGF54_RS16430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGF54_RS16440	COG2197	response regulator
FGF54_RS16475	COG3307	-O-antigen
FGF54_RS16480	COG1596	polysaccharide export
FGF54_RS16485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGF54_RS16500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FGF54_RS16505	COG0840	transmembrane signaling receptor activity
FGF54_RS16510	COG1376	ErfK ybiS ycfS ynhG family protein
FGF54_RS16530	COG2094	Belongs to the DNA glycosylase MPG family
FGF54_RS16545	COG1609	Transcriptional regulator
FGF54_RS16550	COG1653	transport
FGF54_RS16575	COG0673	inositol 2-dehydrogenase activity
FGF54_RS16580	COG0602	queuosine metabolic process
FGF54_RS16585	COG0720	synthase
FGF54_RS16590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FGF54_RS16595	COG0673	inositol 2-dehydrogenase activity
FGF54_RS16610	COG0395	ABC-type sugar transport system, permease component
FGF54_RS16615	COG1175	transmembrane transport
FGF54_RS16640	COG0583	DNA-binding transcription factor activity
FGF54_RS16645	COG0281	malic enzyme
FGF54_RS16645	COG0280	phosphate acetyltransferase
FGF54_RS16660	COG0765	amino acid transport
FGF54_RS16665	COG1126	abc transporter atp-binding protein
FGF54_RS16670	COG2079	MmgE PrpD family protein
FGF54_RS16675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS16685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS16705	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FGF54_RS16715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FGF54_RS16720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FGF54_RS16725	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS16730	COG1129	ABC transporter
FGF54_RS16745	COG1473	amidohydrolase
FGF54_RS16760	COG4172	Belongs to the ABC transporter superfamily
FGF54_RS16765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS16770	COG0601	transmembrane transport
FGF54_RS16775	COG0583	DNA-binding transcription factor activity
FGF54_RS16780	COG1446	asparaginase
FGF54_RS16795	COG0747	negative chemotaxis
FGF54_RS16815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS16820	COG0601	transmembrane transport
FGF54_RS16825	COG2197	response regulator
FGF54_RS16830	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FGF54_RS16835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGF54_RS16850	COG0395	ABC-type sugar transport system, permease component
FGF54_RS16855	COG1175	transmembrane transport
FGF54_RS16865	COG0673	inositol 2-dehydrogenase activity
FGF54_RS16870	COG0673	inositol 2-dehydrogenase activity
FGF54_RS16890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGF54_RS16895	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FGF54_RS16915	COG1595	DNA-templated transcription, initiation
FGF54_RS16920	COG1120	ATPase activity
FGF54_RS16925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGF54_RS16940	COG2226	methyltransferase
FGF54_RS16950	COG1120	ATPase activity
FGF54_RS16955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGF54_RS16975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGF54_RS17000	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS17005	COG0473	3-isopropylmalate dehydrogenase activity
FGF54_RS17010	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS17020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS17060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS17065	COG4172	Belongs to the ABC transporter superfamily
FGF54_RS17070	COG1522	sequence-specific DNA binding
FGF54_RS17080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS17095	COG0583	DNA-binding transcription factor activity
FGF54_RS17105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGF54_RS17110	COG1126	abc transporter atp-binding protein
FGF54_RS17120	COG1473	amidohydrolase
FGF54_RS17125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS17130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS17135	COG1959	2 iron, 2 sulfur cluster binding
FGF54_RS17145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FGF54_RS17150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS17180	COG1960	acyl-CoA dehydrogenase activity
FGF54_RS17205	COG0444	Belongs to the ABC transporter superfamily
FGF54_RS17215	COG0667	Aldo Keto reductase
FGF54_RS17225	COG0583	DNA-binding transcription factor activity
FGF54_RS17230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS17235	COG4166	transmembrane transport
FGF54_RS17245	COG0747	negative chemotaxis
FGF54_RS17250	COG1473	amidohydrolase
FGF54_RS17255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS17260	COG0702	epimerase
FGF54_RS17275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS17295	COG4608	Belongs to the ABC transporter superfamily
FGF54_RS17300	COG0444	Belongs to the ABC transporter superfamily
FGF54_RS17310	COG0601	transmembrane transport
FGF54_RS17320	COG2186	Transcriptional regulator
FGF54_RS17335	COG0300	oxidoreductase activity
FGF54_RS17345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGF54_RS17345	COG3453	Protein conserved in bacteria
FGF54_RS17350	COG0640	Transcriptional regulator
FGF54_RS17360	COG2391	methyltransferase activity
FGF54_RS17365	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FGF54_RS17380	COG0022	dehydrogenase e1 component
FGF54_RS17390	COG1960	acyl-CoA dehydrogenase activity
FGF54_RS17395	COG0183	Belongs to the thiolase family
FGF54_RS17405	COG1960	acyl-CoA dehydrogenase activity
FGF54_RS17410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGF54_RS17425	COG1024	Enoyl-CoA hydratase
FGF54_RS17430	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FGF54_RS17435	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FGF54_RS17440	COG4952	isomerase
FGF54_RS17445	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS17445	COG3347	Dehydrogenase
FGF54_RS17450	COG1349	DNA-binding transcription factor activity
FGF54_RS17465	COG1129	ABC transporter
FGF54_RS17470	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS17475	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS17480	COG3254	rhamnose metabolic process
FGF54_RS17495	COG2264	protein methyltransferase activity
FGF54_RS17500	COG5001	Diguanylate cyclase
FGF54_RS17515	COG4335	DNA alkylation repair
FGF54_RS17520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FGF54_RS17525	COG4208	sulfate ABC transporter
FGF54_RS17540	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FGF54_RS17555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FGF54_RS17565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGF54_RS17575	COG1040	competence protein
FGF54_RS17580	COG2226	methyltransferase
FGF54_RS17595	COG0494	nUDIX hydrolase
FGF54_RS17605	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FGF54_RS17610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGF54_RS17615	COG0653	protein targeting
FGF54_RS17620	COG0697	spore germination
FGF54_RS17705	COG2244	polysaccharide biosynthetic process
FGF54_RS17720	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FGF54_RS17730	COG0489	protein tyrosine kinase activity
FGF54_RS17730	COG3206	protein involved in exopolysaccharide biosynthesis
FGF54_RS17750	COG0438	transferase activity, transferring glycosyl groups
FGF54_RS17755	COG0438	transferase activity, transferring glycosyl groups
FGF54_RS17780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGF54_RS17785	COG2273	Hydrolase Family 16
FGF54_RS17785	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FGF54_RS17830	COG1396	sequence-specific DNA binding
FGF54_RS17840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGF54_RS17845	COG1129	ABC transporter
FGF54_RS17850	COG4214	carbohydrate transport
FGF54_RS17860	COG4213	ABC transporter substrate-binding protein
FGF54_RS17875	COG0346	lactoylglutathione lyase activity
FGF54_RS17880	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGF54_RS17880	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGF54_RS17885	COG4770	biotin carboxylase activity
FGF54_RS17895	COG0625	glutathione transferase activity
FGF54_RS17900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGF54_RS17905	COG3800	Transcriptional regulator
FGF54_RS17905	COG1396	sequence-specific DNA binding
FGF54_RS17915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGF54_RS17925	COG0300	oxidoreductase activity
FGF54_RS17935	COG2096	Adenosyltransferase
FGF54_RS17945	COG2086	electron transfer activity
FGF54_RS17955	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGF54_RS17965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGF54_RS17970	COG0165	Argininosuccinate lyase
FGF54_RS18005	COG2884	Cell division ATP-binding protein ftsE
FGF54_RS18025	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FGF54_RS18040	COG0287	Prephenate dehydrogenase
FGF54_RS18045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGF54_RS18050	COG2226	methyltransferase
FGF54_RS18055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGF54_RS18070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGF54_RS18075	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FGF54_RS18110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FGF54_RS18115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGF54_RS18130	COG4974	Belongs to the 'phage' integrase family
FGF54_RS18135	COG0825	malonyl-CoA metabolic process
FGF54_RS18140	COG3034	peptidoglycan biosynthetic process
FGF54_RS18145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGF54_RS18145	COG0425	Belongs to the sulfur carrier protein TusA family
FGF54_RS18150	COG0523	cobalamin synthesis protein
FGF54_RS18155	COG1686	Belongs to the peptidase S11 family
FGF54_RS18160	COG1473	amidohydrolase
FGF54_RS18165	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FGF54_RS18170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FGF54_RS18180	COG2706	6-phosphogluconolactonase activity
FGF54_RS18205	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FGF54_RS18240	COG0673	inositol 2-dehydrogenase activity
FGF54_RS18250	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS18260	COG3962	Belongs to the TPP enzyme family
FGF54_RS18265	COG0673	inositol 2-dehydrogenase activity
FGF54_RS18270	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS18280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGF54_RS18305	COG1129	ABC transporter
FGF54_RS18315	COG4953	penicillin-binding protein 1C
FGF54_RS18320	COG2373	Large extracellular alpha-helical protein
FGF54_RS18325	COG2835	tetraacyldisaccharide 4'-kinase activity
FGF54_RS18485	COG4373	Mu-like prophage FluMu protein gp28
FGF54_RS18490	COG4383	Mu-like prophage protein gp29
FGF54_RS18515	COG4397	Mu-like prophage major head subunit gpT
FGF54_RS18535	COG4387	Mu-like prophage protein GP36
FGF54_RS18590	COG3299	homolog of phage Mu protein gp47
FGF54_RS18625	COG0482	sulfurtransferase activity
FGF54_RS18640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGF54_RS18655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGF54_RS18660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGF54_RS18665	COG0037	tRNA processing
FGF54_RS18675	COG2885	chlorophyll binding
FGF54_RS18680	COG0823	Involved in the tonB-independent uptake of proteins
FGF54_RS18700	COG0824	Thioesterase
FGF54_RS18710	COG0494	nUDIX hydrolase
FGF54_RS18725	COG2255	four-way junction helicase activity
FGF54_RS18740	COG0632	four-way junction helicase activity
FGF54_RS18745	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FGF54_RS18750	COG0840	transmembrane signaling receptor activity
FGF54_RS18755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS18760	COG0217	transcriptional regulatory protein
FGF54_RS18775	COG1692	metallophosphoesterase
FGF54_RS18785	COG1253	flavin adenine dinucleotide binding
FGF54_RS18835	COG0126	phosphoglycerate kinase activity
FGF54_RS18840	COG3588	fructose-bisphosphate aldolase
FGF54_RS18845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FGF54_RS18845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FGF54_RS18850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FGF54_RS18865	COG1414	Transcriptional regulator
FGF54_RS18920	COG0254	rRNA binding
FGF54_RS18925	COG1132	(ABC) transporter
FGF54_RS18945	COG0483	inositol monophosphate 1-phosphatase activity
FGF54_RS18975	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FGF54_RS18980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FGF54_RS18985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGF54_RS18990	COG0457	Tetratricopeptide repeat
FGF54_RS18995	COG3750	Belongs to the UPF0335 family
FGF54_RS19015	COG0469	pyruvate kinase activity
FGF54_RS19020	COG3108	Peptidase M15
FGF54_RS19025	COG2204	response regulator
FGF54_RS19030	COG1164	Oligoendopeptidase f
FGF54_RS19035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGF54_RS19045	COG5310	Homospermidine synthase
FGF54_RS19055	COG0737	Belongs to the 5'-nucleotidase family
FGF54_RS19060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FGF54_RS19065	COG0330	HflC and HflK could
FGF54_RS19095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGF54_RS19100	COG2951	lytic endotransglycosylase activity
FGF54_RS19115	COG2205	protein histidine kinase activity
FGF54_RS19125	COG0070	glutamate synthase
FGF54_RS19125	COG0069	glutamate synthase activity
FGF54_RS19125	COG0067	glutamate synthase
FGF54_RS19140	COG2205	protein histidine kinase activity
FGF54_RS19145	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FGF54_RS19150	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FGF54_RS19155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FGF54_RS19165	COG0252	asparaginase activity
FGF54_RS19175	COG1027	Aspartate ammonia-lyase
FGF54_RS19180	COG2186	Transcriptional regulator
FGF54_RS19210	COG3842	ATPase activity
FGF54_RS19215	COG1177	transmembrane transport
FGF54_RS19235	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS19240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS19250	COG2267	carboxylic ester hydrolase activity
FGF54_RS19275	COG4176	ABC-type proline glycine betaine transport system permease component
FGF54_RS19280	COG0517	IMP dehydrogenase activity
FGF54_RS19280	COG4175	Glycine betaine
FGF54_RS19285	COG2986	histidine ammonia-lyase
FGF54_RS19300	COG0174	glutamine synthetase
FGF54_RS19305	COG0069	glutamate synthase activity
FGF54_RS19310	COG2218	PFAM glutamate synthase alpha subunit domain protein
FGF54_RS19315	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FGF54_RS19325	COG4977	sequence-specific DNA binding
FGF54_RS19330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS19335	COG4311	Sarcosine oxidase, delta subunit
FGF54_RS19340	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGF54_RS19340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGF54_RS19350	COG1609	Transcriptional regulator
FGF54_RS19370	COG1082	Xylose isomerase domain protein TIM barrel
FGF54_RS19375	COG0673	inositol 2-dehydrogenase activity
FGF54_RS19380	COG1082	Xylose isomerase domain protein TIM barrel
FGF54_RS19390	COG2957	Belongs to the agmatine deiminase family
FGF54_RS19405	COG3550	peptidyl-serine autophosphorylation
FGF54_RS19500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGF54_RS19505	COG4172	Belongs to the ABC transporter superfamily
FGF54_RS19510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS19515	COG0601	transmembrane transport
FGF54_RS19520	COG0747	negative chemotaxis
FGF54_RS19530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FGF54_RS19535	COG1454	alcohol dehydrogenase
FGF54_RS19580	COG2307	Protein conserved in bacteria
FGF54_RS19580	COG2308	Evidence 4 Homologs of previously reported genes of
FGF54_RS19595	COG0488	(ABC) transporter
FGF54_RS19600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGF54_RS19605	COG2186	Transcriptional regulator
FGF54_RS19620	COG1175	transmembrane transport
FGF54_RS19625	COG0395	ABC-type sugar transport system, permease component
FGF54_RS19635	COG3842	ATPase activity
FGF54_RS19660	COG1304	FMN binding
FGF54_RS19675	COG1063	alcohol dehydrogenase
FGF54_RS19680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FGF54_RS19685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGF54_RS19695	COG0765	amino acid transport
FGF54_RS19700	COG0765	amino acid transport
FGF54_RS19705	COG4221	oxidoreductase activity
FGF54_RS19710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGF54_RS19720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGF54_RS19735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FGF54_RS19750	COG0697	spore germination
FGF54_RS19755	COG0697	spore germination
FGF54_RS19760	COG0511	ligase activity, forming carbon-carbon bonds
FGF54_RS19765	COG0439	Biotin carboxylase
FGF54_RS19775	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FGF54_RS19780	COG1984	allophanate hydrolase subunit 2
FGF54_RS19785	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FGF54_RS19790	COG3842	ATPase activity
FGF54_RS19800	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FGF54_RS19810	COG0436	Aminotransferase
FGF54_RS19815	COG4221	oxidoreductase activity
FGF54_RS19825	COG0840	transmembrane signaling receptor activity
FGF54_RS19830	COG1070	Carbohydrate kinase
FGF54_RS19835	COG1830	Aldolase
FGF54_RS19840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FGF54_RS19845	COG0667	Aldo Keto reductase
FGF54_RS19855	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS19860	COG1129	ABC transporter
FGF54_RS19865	COG1879	ABC-type sugar transport system periplasmic component
FGF54_RS19870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGF54_RS19880	COG1609	Transcriptional regulator
FGF54_RS19885	COG1053	succinate dehydrogenase
FGF54_RS19885	COG3976	FMN-binding domain protein
FGF54_RS19895	COG1175	transmembrane transport
FGF54_RS19900	COG0395	ABC-type sugar transport system, permease component
FGF54_RS19905	COG3842	ATPase activity
FGF54_RS19920	COG0747	negative chemotaxis
FGF54_RS19925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGF54_RS19940	COG0601	transmembrane transport
FGF54_RS19945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS19955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGF54_RS19960	COG4172	Belongs to the ABC transporter superfamily
FGF54_RS19965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS19970	COG0601	transmembrane transport
FGF54_RS19975	COG4166	transmembrane transport
FGF54_RS20015	COG0071	Belongs to the small heat shock protein (HSP20) family
FGF54_RS20030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FGF54_RS20045	COG0395	ABC-type sugar transport system, permease component
FGF54_RS20060	COG3842	ATPase activity
FGF54_RS20085	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGF54_RS20115	COG0559	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS20160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGF54_RS20160	COG1648	precorrin-2 dehydrogenase activity
FGF54_RS20165	COG0243	molybdopterin cofactor binding
FGF54_RS20180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGF54_RS20185	COG1116	anion transmembrane transporter activity
FGF54_RS20190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS20195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGF54_RS20200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGF54_RS20205	COG3707	response regulator
FGF54_RS20210	COG1802	Transcriptional regulator
FGF54_RS20215	COG1914	H( )-stimulated, divalent metal cation uptake system
FGF54_RS20220	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FGF54_RS20225	COG4336	lyase activity
FGF54_RS20230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FGF54_RS20235	COG4770	biotin carboxylase activity
FGF54_RS20240	COG0366	Alpha amylase catalytic
FGF54_RS20250	COG4771	TonB-dependent receptor
FGF54_RS20275	COG1414	Transcriptional regulator
FGF54_RS20280	COG1475	DNA binding
FGF54_RS20285	COG1192	Involved in chromosome partitioning
FGF54_RS20315	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FGF54_RS20325	COG2986	histidine ammonia-lyase
FGF54_RS20330	COG1228	amidohydrolase
FGF54_RS20335	COG0402	S-adenosylhomocysteine deaminase activity
FGF54_RS20425	COG1846	Transcriptional regulator
FGF54_RS20430	COG0583	DNA-binding transcription factor activity
FGF54_RS20435	COG2828	Protein conserved in bacteria
FGF54_RS20450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS20470	COG0840	transmembrane signaling receptor activity
FGF54_RS20475	COG0431	NADPH-dependent FMN reductase
FGF54_RS20505	COG1215	transferase activity, transferring glycosyl groups
FGF54_RS20515	COG0583	DNA-binding transcription factor activity
FGF54_RS20520	COG0346	lactoylglutathione lyase activity
FGF54_RS20535	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FGF54_RS20560	COG1309	transcriptional regulator
FGF54_RS20565	COG2268	Band 7 protein
FGF54_RS20575	COG1842	Phage shock protein A
FGF54_RS20585	COG0583	DNA-binding transcription factor activity
FGF54_RS20590	COG0477	Major facilitator Superfamily
FGF54_RS20610	COG4774	siderophore transport
FGF54_RS20640	COG0671	phosphoesterase, PA-phosphatase related
FGF54_RS20695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FGF54_RS20705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FGF54_RS20710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FGF54_RS20715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGF54_RS20730	COG0010	Belongs to the arginase family
FGF54_RS20740	COG0697	spore germination
FGF54_RS20745	COG0673	inositol 2-dehydrogenase activity
FGF54_RS20770	COG0477	Major facilitator Superfamily
FGF54_RS20785	COG2194	sulfuric ester hydrolase activity
FGF54_RS20795	COG0583	DNA-binding transcription factor activity
FGF54_RS20800	COG4774	siderophore transport
FGF54_RS20815	COG1120	ATPase activity
FGF54_RS20825	COG3474	cytochrome
FGF54_RS20830	COG2137	regulation of response to DNA damage stimulus
FGF54_RS20835	COG3386	PFAM SMP-30 Gluconolaconase
FGF54_RS20845	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS20850	COG1129	ABC transporter
FGF54_RS20855	COG1879	ABC-type sugar transport system periplasmic component
FGF54_RS20865	COG4585	Histidine kinase
FGF54_RS20870	COG2197	response regulator
FGF54_RS20880	COG2133	pyrroloquinoline quinone binding
FGF54_RS20890	COG0500	methyltransferase
FGF54_RS20895	COG0564	pseudouridine synthase activity
FGF54_RS20910	COG4175	Glycine betaine
FGF54_RS20910	COG3448	diguanylate cyclase activity
FGF54_RS20915	COG4176	ABC-type proline glycine betaine transport system permease component
FGF54_RS20925	COG0784	Response regulator, receiver
FGF54_RS20925	COG4191	Histidine kinase
FGF54_RS20935	COG3206	protein involved in exopolysaccharide biosynthesis
FGF54_RS20935	COG0489	protein tyrosine kinase activity
FGF54_RS20940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGF54_RS20945	COG1215	transferase activity, transferring glycosyl groups
FGF54_RS20950	COG1215	transferase activity, transferring glycosyl groups
FGF54_RS20955	COG1215	transferase activity, transferring glycosyl groups
FGF54_RS20960	COG0438	transferase activity, transferring glycosyl groups
FGF54_RS20965	COG2273	Hydrolase Family 16
FGF54_RS20970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FGF54_RS20975	COG2244	polysaccharide biosynthetic process
FGF54_RS20980	COG0463	Glycosyl transferase, family 2
FGF54_RS20985	COG2327	Polysaccharide pyruvyl transferase
FGF54_RS20990	COG1215	transferase activity, transferring glycosyl groups
FGF54_RS21010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FGF54_RS21020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS21035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGF54_RS21035	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGF54_RS21060	COG0033	Phosphoglucomutase
FGF54_RS21065	COG0297	glycogen (starch) synthase activity
FGF54_RS21070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FGF54_RS21075	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FGF54_RS21080	COG0058	SHG alpha-glucan phosphorylase activity
FGF54_RS21095	COG1794	racemase activity, acting on amino acids and derivatives
FGF54_RS21100	COG1522	sequence-specific DNA binding
FGF54_RS21110	COG2084	Dehydrogenase
FGF54_RS21115	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS21120	COG1063	alcohol dehydrogenase
FGF54_RS21135	COG4988	ABC transporter
FGF54_RS21140	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FGF54_RS21150	COG1294	oxidase, subunit
FGF54_RS21180	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FGF54_RS21185	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FGF54_RS21215	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FGF54_RS21220	COG0539	negative regulation of cytoplasmic translation
FGF54_RS21250	COG4221	oxidoreductase activity
FGF54_RS21260	COG0006	proline dipeptidase activity
FGF54_RS21265	COG0747	negative chemotaxis
FGF54_RS21270	COG0601	transmembrane transport
FGF54_RS21275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS21280	COG0444	Belongs to the ABC transporter superfamily
FGF54_RS21285	COG4608	Belongs to the ABC transporter superfamily
FGF54_RS21290	COG0246	Mannitol dehydrogenase
FGF54_RS21305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS21350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGF54_RS21355	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS21375	COG4993	Dehydrogenase
FGF54_RS21380	COG3685	Protein conserved in bacteria
FGF54_RS21385	COG1285	pathogenesis
FGF54_RS21390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS21410	COG0693	protein deglycase activity
FGF54_RS21435	COG0189	ligase activity
FGF54_RS21440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGF54_RS21445	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FGF54_RS21455	COG0435	Glutathione S-transferase
FGF54_RS21460	COG0583	DNA-binding transcription factor activity
FGF54_RS21465	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS21470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGF54_RS21475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS21480	COG1116	anion transmembrane transporter activity
FGF54_RS21490	COG1522	sequence-specific DNA binding
FGF54_RS21505	COG0784	Response regulator, receiver
FGF54_RS21515	COG3920	Histidine kinase
FGF54_RS21525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGF54_RS21540	COG0019	diaminopimelate decarboxylase activity
FGF54_RS21560	COG0527	aspartate kinase activity
FGF54_RS21570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FGF54_RS21575	COG2890	protein-(glutamine-N5) methyltransferase activity
FGF54_RS21590	COG0542	response to heat
FGF54_RS21595	COG0739	heme binding
FGF54_RS21595	COG1196	nuclear chromosome segregation
FGF54_RS21595	COG0741	lytic transglycosylase activity
FGF54_RS21645	COG3609	addiction module antidote protein, CC2985 family
FGF54_RS21770	COG2311	Membrane
FGF54_RS21805	COG1917	Cupin 2, conserved barrel domain protein
FGF54_RS21805	COG2207	Transcriptional regulator
FGF54_RS21830	COG1475	DNA binding
FGF54_RS21905	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGF54_RS21935	COG0484	heat shock protein binding
FGF54_RS21970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FGF54_RS21990	COG0542	response to heat
FGF54_RS22000	COG2837	iron assimilation
FGF54_RS22010	COG1252	NADH dehydrogenase
FGF54_RS22015	COG0431	NADPH-dependent FMN reductase
FGF54_RS22020	COG0604	alcohol dehydrogenase
FGF54_RS22020	COG3321	synthase
FGF54_RS22020	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS22025	COG2095	MarC family integral membrane protein
FGF54_RS22030	COG3781	membrane
FGF54_RS22035	COG0243	molybdopterin cofactor binding
FGF54_RS22040	COG1271	oxidase subunit
FGF54_RS22045	COG1294	oxidase, subunit
FGF54_RS22075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGF54_RS22080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGF54_RS22095	COG2186	Transcriptional regulator
FGF54_RS22100	COG0247	lactate metabolic process
FGF54_RS22100	COG0277	FAD linked oxidase domain protein
FGF54_RS22105	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS22110	COG4221	oxidoreductase activity
FGF54_RS22120	COG0028	Belongs to the TPP enzyme family
FGF54_RS22135	COG0436	Aminotransferase
FGF54_RS22140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGF54_RS22145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS22150	COG0583	DNA-binding transcription factor activity
FGF54_RS22180	COG2086	electron transfer activity
FGF54_RS22200	COG2376	Dihydroxyacetone kinase
FGF54_RS22205	COG1522	sequence-specific DNA binding
FGF54_RS22225	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FGF54_RS22230	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FGF54_RS22250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS22265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS22275	COG0747	negative chemotaxis
FGF54_RS22290	COG0277	FAD linked oxidase domain protein
FGF54_RS22310	COG0778	Nitroreductase
FGF54_RS22330	COG0583	DNA-binding transcription factor activity
FGF54_RS22350	COG0395	ABC-type sugar transport system, permease component
FGF54_RS22355	COG3842	ATPase activity
FGF54_RS22365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGF54_RS22380	COG3842	ATPase activity
FGF54_RS22385	COG1177	transmembrane transport
FGF54_RS22415	COG3842	ATPase activity
FGF54_RS22425	COG1177	transmembrane transport
FGF54_RS22430	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGF54_RS22445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGF54_RS22470	COG0583	DNA-binding transcription factor activity
FGF54_RS22485	COG1335	isochorismatase
FGF54_RS22510	COG3842	ATPase activity
FGF54_RS22515	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGF54_RS22520	COG1177	transmembrane transport
FGF54_RS22525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FGF54_RS22535	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FGF54_RS22550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FGF54_RS22555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FGF54_RS22560	COG1845	cytochrome c oxidase, subunit III
FGF54_RS22575	COG4977	sequence-specific DNA binding
FGF54_RS22575	COG1917	Cupin 2, conserved barrel domain protein
FGF54_RS22580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS22590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGF54_RS22590	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGF54_RS22600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGF54_RS22605	COG1760	l-serine dehydratase
FGF54_RS22620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGF54_RS22625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGF54_RS22650	COG1309	transcriptional regulator
FGF54_RS22660	COG1063	alcohol dehydrogenase
FGF54_RS22670	COG1879	ABC-type sugar transport system periplasmic component
FGF54_RS22680	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS22835	COG5001	Diguanylate cyclase
FGF54_RS22835	COG3300	MHYT domain
FGF54_RS22840	COG0483	inositol monophosphate 1-phosphatase activity
FGF54_RS22865	COG1178	ABC-type Fe3 transport system permease component
FGF54_RS22870	COG3842	ATPase activity
FGF54_RS22905	COG3842	ATPase activity
FGF54_RS22910	COG0395	ABC-type sugar transport system, permease component
FGF54_RS22915	COG1175	transmembrane transport
FGF54_RS22920	COG1653	transport
FGF54_RS22930	COG0673	inositol 2-dehydrogenase activity
FGF54_RS22935	COG1609	Transcriptional regulator
FGF54_RS22950	COG0583	DNA-binding transcription factor activity
FGF54_RS22955	COG2423	ornithine cyclodeaminase activity
FGF54_RS22960	COG0251	oxidation-reduction process
FGF54_RS22965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FGF54_RS22970	COG0477	Major facilitator Superfamily
FGF54_RS22980	COG0583	DNA-binding transcription factor activity
FGF54_RS22990	COG1879	ABC-type sugar transport system periplasmic component
FGF54_RS22995	COG1129	ABC transporter
FGF54_RS23000	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS23005	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS23010	COG1609	Transcriptional regulator
FGF54_RS23020	COG0673	inositol 2-dehydrogenase activity
FGF54_RS23080	COG0714	Associated with various cellular activities
FGF54_RS23085	COG3256	nitric oxide reductase
FGF54_RS23100	COG1845	cytochrome c oxidase, subunit III
FGF54_RS23115	COG0163	prenyltransferase activity
FGF54_RS23120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FGF54_RS23125	COG3189	MarR family transcriptional regulator
FGF54_RS23135	COG0826	peptidase U32
FGF54_RS23170	COG4459	periplasmic nitrate reductase
FGF54_RS23185	COG0243	molybdopterin cofactor binding
FGF54_RS23195	COG3005	denitrification pathway
FGF54_RS23210	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS23215	COG1535	isochorismatase
FGF54_RS23215	COG3433	isochorismatase activity
FGF54_RS23220	COG1021	2,3-dihydroxybenzoate-AMP ligase
FGF54_RS23225	COG1169	isochorismate synthase
FGF54_RS23235	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FGF54_RS23235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGF54_RS23240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGF54_RS23250	COG2375	cellular response to nickel ion
FGF54_RS23260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGF54_RS23265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGF54_RS23270	COG1120	ATPase activity
FGF54_RS23275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGF54_RS23285	COG4774	siderophore transport
FGF54_RS23285	COG1629	transport
FGF54_RS23290	COG1960	acyl-CoA dehydrogenase activity
FGF54_RS23295	COG0583	DNA-binding transcription factor activity
FGF54_RS23300	COG1609	Transcriptional regulator
FGF54_RS23320	COG3842	ATPase activity
FGF54_RS23330	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FGF54_RS23335	COG0583	DNA-binding transcription factor activity
FGF54_RS23340	COG2814	Major facilitator Superfamily
FGF54_RS23345	COG1473	amidohydrolase
FGF54_RS23360	COG0747	negative chemotaxis
FGF54_RS23365	COG0601	transmembrane transport
FGF54_RS23370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS23375	COG0444	Belongs to the ABC transporter superfamily
FGF54_RS23385	COG0583	DNA-binding transcription factor activity
FGF54_RS23395	COG0747	negative chemotaxis
FGF54_RS23405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS23410	COG0154	amidase activity
FGF54_RS23415	COG0693	protein deglycase activity
FGF54_RS23425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS23430	COG0601	transmembrane transport
FGF54_RS23435	COG4166	transmembrane transport
FGF54_RS23440	COG1473	amidohydrolase
FGF54_RS23445	COG4172	Belongs to the ABC transporter superfamily
FGF54_RS23450	COG2390	Transcriptional regulator
FGF54_RS23460	COG1175	transmembrane transport
FGF54_RS23465	COG0395	ABC-type sugar transport system, permease component
FGF54_RS23485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGF54_RS23490	COG1069	ribulokinase activity
FGF54_RS23515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGF54_RS23525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGF54_RS23530	COG1414	Transcriptional regulator
FGF54_RS23535	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS23545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGF54_RS23550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGF54_RS23555	COG1121	(ABC) transporter
FGF54_RS23560	COG0803	Belongs to the bacterial solute-binding protein 9 family
FGF54_RS23570	COG1752	Esterase of the alpha-beta hydrolase superfamily
FGF54_RS23575	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGF54_RS23585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGF54_RS23590	COG0471	metal ion transport
FGF54_RS23590	COG3273	potassium ion transport
FGF54_RS23595	COG2827	Endonuclease containing a URI domain
FGF54_RS23600	COG1253	flavin adenine dinucleotide binding
FGF54_RS23605	COG1309	transcriptional regulator
FGF54_RS23620	COG1609	Transcriptional regulator
FGF54_RS23625	COG1070	Carbohydrate kinase
FGF54_RS23635	COG2115	Belongs to the xylose isomerase family
FGF54_RS23645	COG0778	Nitroreductase
FGF54_RS23650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGF54_RS23655	COG2011	ABC-type metal ion transport system permease component
FGF54_RS23665	COG5001	Diguanylate cyclase
FGF54_RS23665	COG3300	MHYT domain
FGF54_RS23670	COG1054	Belongs to the UPF0176 family
FGF54_RS23680	COG2954	triphosphatase activity
FGF54_RS23685	COG0800	Aldolase
FGF54_RS23705	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FGF54_RS23745	COG0523	cobalamin synthesis protein
FGF54_RS23755	COG1846	Transcriptional regulator
FGF54_RS23760	COG1609	Transcriptional regulator
FGF54_RS23765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGF54_RS23780	COG3718	enzyme involved in inositol metabolism
FGF54_RS23790	COG3962	Belongs to the TPP enzyme family
FGF54_RS23795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGF54_RS23810	COG0411	ABC transporter
FGF54_RS23815	COG0559	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS23825	COG0683	leucine binding
FGF54_RS23840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS23855	COG4172	Belongs to the ABC transporter superfamily
FGF54_RS23875	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FGF54_RS23880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGF54_RS23885	COG1126	abc transporter atp-binding protein
FGF54_RS23890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGF54_RS23895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGF54_RS23900	COG0765	amino acid transport
FGF54_RS23905	COG0765	amino acid transport
FGF54_RS23915	COG3485	protocatechuate 3,4-dioxygenase
FGF54_RS23920	COG3485	protocatechuate 3,4-dioxygenase
FGF54_RS23925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGF54_RS23935	COG0583	DNA-binding transcription factor activity
FGF54_RS23950	COG1414	Transcriptional regulator
FGF54_RS23960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FGF54_RS23965	COG0183	Belongs to the thiolase family
FGF54_RS23970	COG1609	Transcriptional regulator
FGF54_RS23985	COG1082	Xylose isomerase domain protein TIM barrel
FGF54_RS23990	COG0673	inositol 2-dehydrogenase activity
FGF54_RS24000	COG1609	Transcriptional regulator
FGF54_RS24005	COG0395	ABC-type sugar transport system, permease component
FGF54_RS24010	COG1175	transmembrane transport
FGF54_RS24025	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FGF54_RS24045	COG2814	Major facilitator Superfamily
FGF54_RS24050	COG4774	siderophore transport
FGF54_RS24055	COG3712	iron ion homeostasis
FGF54_RS24070	COG0584	glycerophosphoryl diester phosphodiesterase
FGF54_RS24075	COG0300	oxidoreductase activity
FGF54_RS24090	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FGF54_RS24100	COG0385	Bile acid
FGF54_RS24105	COG0667	Aldo Keto reductase
FGF54_RS24110	COG0583	DNA-binding transcription factor activity
FGF54_RS24120	COG1132	(ABC) transporter
FGF54_RS24135	COG1216	Glycosyl transferase, family 2
FGF54_RS24135	COG1442	glycosyl transferase family 8
FGF54_RS24140	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FGF54_RS24150	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FGF54_RS24170	COG3754	Rhamnan synthesis protein F
FGF54_RS24185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FGF54_RS24190	COG1091	dTDP-4-dehydrorhamnose reductase activity
FGF54_RS24195	COG1088	dTDP-glucose 4,6-dehydratase activity
FGF54_RS24200	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FGF54_RS24215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGF54_RS24220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGF54_RS24225	COG1120	ATPase activity
FGF54_RS24230	COG4774	siderophore transport
FGF54_RS24235	COG0210	DNA helicase
FGF54_RS24240	COG4608	Belongs to the ABC transporter superfamily
FGF54_RS24245	COG0444	Belongs to the ABC transporter superfamily
FGF54_RS24250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS24255	COG0601	transmembrane transport
FGF54_RS24260	COG2186	Transcriptional regulator
FGF54_RS24280	COG5001	Diguanylate cyclase
FGF54_RS24280	COG3300	MHYT domain
FGF54_RS24285	COG0306	phosphate transporter
FGF54_RS24290	COG1392	Phosphate transport regulator
FGF54_RS24305	COG1566	PFAM secretion protein HlyD family protein
FGF54_RS24315	COG2205	protein histidine kinase activity
FGF54_RS24330	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FGF54_RS24340	COG4774	siderophore transport
FGF54_RS24350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGF54_RS24355	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGF54_RS24360	COG1120	ATPase activity
FGF54_RS24365	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGF54_RS24405	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS24410	COG0583	DNA-binding transcription factor activity
FGF54_RS24420	COG3119	arylsulfatase activity
FGF54_RS24425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGF54_RS24430	COG3842	ATPase activity
FGF54_RS24435	COG0165	Argininosuccinate lyase
FGF54_RS24440	COG0395	ABC-type sugar transport system, permease component
FGF54_RS24445	COG1175	transmembrane transport
FGF54_RS24450	COG2182	Extracellular solute-binding protein
FGF54_RS24455	COG1940	carbohydrate kinase activity
FGF54_RS24480	COG1486	melibiose metabolic process
FGF54_RS24485	COG0747	negative chemotaxis
FGF54_RS24490	COG0601	transmembrane transport
FGF54_RS24495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS24500	COG4172	Belongs to the ABC transporter superfamily
FGF54_RS24505	COG1486	melibiose metabolic process
FGF54_RS24510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGF54_RS24515	COG0842	Transport permease protein
FGF54_RS24515	COG1129	ABC transporter
FGF54_RS24520	COG0842	Transport permease protein
FGF54_RS24535	COG0784	Response regulator, receiver
FGF54_RS24540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FGF54_RS24550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGF54_RS24555	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FGF54_RS24575	COG0765	amino acid transport
FGF54_RS24585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS24595	COG3938	Belongs to the proline racemase family
FGF54_RS24610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGF54_RS24615	COG0765	amino acid transport
FGF54_RS24620	COG0765	amino acid transport
FGF54_RS24630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGF54_RS24645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FGF54_RS24665	COG3383	formate dehydrogenase (NAD+) activity
FGF54_RS24675	COG2223	nitrite transmembrane transporter activity
FGF54_RS24680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGF54_RS24695	COG0747	negative chemotaxis
FGF54_RS24700	COG0601	transmembrane transport
FGF54_RS24705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS24710	COG4172	Belongs to the ABC transporter superfamily
FGF54_RS24715	COG4948	Mandelate Racemase Muconate Lactonizing
FGF54_RS24725	COG2186	Transcriptional regulator
FGF54_RS24730	COG0747	negative chemotaxis
FGF54_RS24735	COG0601	transmembrane transport
FGF54_RS24740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS24745	COG0405	Gamma-glutamyltransferase
FGF54_RS24755	COG0483	inositol monophosphate 1-phosphatase activity
FGF54_RS24765	COG3842	ATPase activity
FGF54_RS24770	COG0395	ABC-type sugar transport system, permease component
FGF54_RS24800	COG3181	Tripartite tricarboxylate transporter family receptor
FGF54_RS24805	COG5265	(ABC) transporter
FGF54_RS24810	COG0488	(ABC) transporter
FGF54_RS24840	COG0110	maltose O-acetyltransferase activity
FGF54_RS24860	COG1129	ABC transporter
FGF54_RS24865	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS24870	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGF54_RS24885	COG1082	Xylose isomerase domain protein TIM barrel
FGF54_RS24910	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FGF54_RS24920	COG4178	(ABC) transporter
FGF54_RS24935	COG1940	carbohydrate kinase activity
FGF54_RS24935	COG1846	Transcriptional regulator
FGF54_RS24955	COG1069	ribulokinase activity
FGF54_RS24960	COG1349	DNA-binding transcription factor activity
FGF54_RS24965	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS24990	COG0395	ABC-type sugar transport system, permease component
FGF54_RS25000	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS25020	COG0640	Transcriptional regulator
FGF54_RS25070	COG3609	addiction module antidote protein, CC2985 family
FGF54_RS25135	COG0776	regulation of translation
FGF54_RS25155	COG3505	Type IV secretory pathway VirD4
FGF54_RS25185	COG2207	Transcriptional regulator
FGF54_RS25195	COG2169	Transcriptional regulator
FGF54_RS25215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGF54_RS25225	COG2801	Transposase and inactivated derivatives
FGF54_RS25230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGF54_RS25235	COG2826	transposase and inactivated derivatives, IS30 family
FGF54_RS25255	COG2337	Toxic component of a toxin-antitoxin (TA) module
FGF54_RS25265	COG4178	(ABC) transporter
FGF54_RS25325	COG1309	transcriptional regulator
FGF54_RS25360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGF54_RS25395	COG1294	oxidase, subunit
FGF54_RS25400	COG1271	oxidase subunit
FGF54_RS25410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGF54_RS25435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGF54_RS25440	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FGF54_RS25455	COG1116	anion transmembrane transporter activity
FGF54_RS25460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGF54_RS25465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS25470	COG0800	Aldolase
FGF54_RS25480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGF54_RS25485	COG0156	8-amino-7-oxononanoate synthase activity
FGF54_RS25490	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGF54_RS25500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGF54_RS25505	COG1120	ATPase activity
FGF54_RS25510	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FGF54_RS25515	COG4139	cobalamin transport
FGF54_RS25525	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS25530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FGF54_RS25535	COG1984	allophanate hydrolase subunit 2
FGF54_RS25545	COG0439	Biotin carboxylase
FGF54_RS25555	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FGF54_RS25560	COG0583	DNA-binding transcription factor activity
FGF54_RS25570	COG0318	PFAM AMP-dependent synthetase and ligase
FGF54_RS25585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGF54_RS25645	COG3842	ATPase activity
FGF54_RS25650	COG1178	ABC-type Fe3 transport system permease component
FGF54_RS25695	COG2072	flavoprotein involved in K transport
FGF54_RS25705	COG2144	transferase activity, transferring acyl groups
FGF54_RS25715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FGF54_RS25730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGF54_RS25740	COG0583	DNA-binding transcription factor activity
FGF54_RS25750	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS25760	COG1414	Transcriptional regulator
FGF54_RS25770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FGF54_RS25775	COG0183	Belongs to the thiolase family
FGF54_RS25780	COG1116	anion transmembrane transporter activity
FGF54_RS25780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGF54_RS25790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS25800	COG1414	Transcriptional regulator
FGF54_RS25820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FGF54_RS25830	COG0154	amidase activity
FGF54_RS25860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGF54_RS25865	COG3181	Tripartite tricarboxylate transporter family receptor
FGF54_RS25885	COG0154	amidase activity
FGF54_RS25910	COG0673	inositol 2-dehydrogenase activity
FGF54_RS25920	COG1609	Transcriptional regulator
FGF54_RS25930	COG1175	transmembrane transport
FGF54_RS25935	COG0395	ABC-type sugar transport system, permease component
FGF54_RS25950	COG0673	inositol 2-dehydrogenase activity
FGF54_RS25960	COG1024	Enoyl-CoA hydratase
FGF54_RS25970	COG0318	PFAM AMP-dependent synthetase and ligase
FGF54_RS25975	COG0583	DNA-binding transcription factor activity
FGF54_RS25985	COG1024	Enoyl-CoA hydratase
FGF54_RS26000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FGF54_RS26005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FGF54_RS26020	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS26030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGF54_RS26035	COG3181	Tripartite tricarboxylate transporter family receptor
FGF54_RS26080	COG3842	ATPase activity
FGF54_RS26085	COG0395	ABC-type sugar transport system, permease component
FGF54_RS26090	COG1175	transmembrane transport
FGF54_RS26125	COG0028	Belongs to the TPP enzyme family
FGF54_RS26130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGF54_RS26145	COG4948	Mandelate Racemase Muconate Lactonizing
FGF54_RS26160	COG3836	Belongs to the HpcH HpaI aldolase family
FGF54_RS26170	COG0579	oxidoreductase
FGF54_RS26205	COG4608	Belongs to the ABC transporter superfamily
FGF54_RS26210	COG0444	Belongs to the ABC transporter superfamily
FGF54_RS26215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS26220	COG0601	transmembrane transport
FGF54_RS26255	COG4948	Mandelate Racemase Muconate Lactonizing
FGF54_RS26270	COG0183	Belongs to the thiolase family
FGF54_RS26275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FGF54_RS26280	COG4608	Belongs to the ABC transporter superfamily
FGF54_RS26290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGF54_RS26295	COG0601	transmembrane transport
FGF54_RS26305	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGF54_RS26310	COG0235	Class ii aldolase
FGF54_RS26315	COG3395	kinase activity
FGF54_RS26325	COG0022	dehydrogenase e1 component
FGF54_RS26325	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGF54_RS26330	COG0747	negative chemotaxis
FGF54_RS26365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGF54_RS26380	COG2072	flavoprotein involved in K transport
FGF54_RS26385	COG1028	Short-chain dehydrogenase reductase Sdr
FGF54_RS26405	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS26415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGF54_RS26420	COG3048	D-serine ammonia-lyase activity
FGF54_RS26440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGF54_RS26450	COG1999	signal sequence binding
FGF54_RS26495	COG3920	Histidine kinase
FGF54_RS26495	COG2202	Pas domain
FGF54_RS26505	COG5489	Protein of unknown function (DUF736)
FGF54_RS26515	COG3077	Addiction module antitoxin, RelB DinJ family
FGF54_RS26530	COG2818	Glycosylase
FGF54_RS26540	COG1309	transcriptional regulator
FGF54_RS26545	COG1902	pentaerythritol trinitrate reductase activity
FGF54_RS26550	COG0840	transmembrane signaling receptor activity
FGF54_RS26555	COG0835	chemotaxis
FGF54_RS26560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGF54_RS26570	COG3547	Transposase (IS116 IS110 IS902 family)
FGF54_RS26580	COG0583	DNA-binding transcription factor activity
FGF54_RS26605	COG2207	Transcriptional regulator
FGF54_RS26625	COG0583	DNA-binding transcription factor activity
FGF54_RS26640	COG0765	amino acid transport
FGF54_RS26645	COG1126	abc transporter atp-binding protein
FGF54_RS26650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGF54_RS26655	COG0028	Belongs to the TPP enzyme family
FGF54_RS26660	COG0247	lactate metabolic process
FGF54_RS26660	COG0277	FAD linked oxidase domain protein
FGF54_RS26665	COG0436	Aminotransferase
FGF54_RS26670	COG1012	belongs to the aldehyde dehydrogenase family
FGF54_RS26675	COG5383	Protein conserved in bacteria
FGF54_RS26680	COG0583	DNA-binding transcription factor activity
FGF54_RS26810	COG1192	Involved in chromosome partitioning
FGF54_RS26815	COG1475	DNA binding
FGF54_RS26820	COG0640	Transcriptional regulator
FGF54_RS26875	COG2205	protein histidine kinase activity
FGF54_RS26885	COG1674	ftsk spoiiie
FGF54_RS26885	COG1196	nuclear chromosome segregation
FGF54_RS26915	COG1104	cysteine desulfurase activity
FGF54_RS26980	COG3838	Conjugal transfer protein Trbc
FGF54_RS26985	COG3702	type iv secretory pathway
FGF54_RS26990	COG3451	type IV secretory pathway VirB4
FGF54_RS27005	COG3704	protein secretion by the type IV secretion system
FGF54_RS27015	COG3736	Type IV secretory pathway, component VirB8
FGF54_RS27020	COG3504	Conjugal transfer protein
FGF54_RS27025	COG2948	multi-organism process
FGF54_RS27030	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis