locus-tag	class	description
At15955_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
At15955_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
At15955_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
At15955_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
At15955_RS00025	COG1420	regulation of RNA biosynthetic process
At15955_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
At15955_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
At15955_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
At15955_RS00050	COG1137	ATPase activity
At15955_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
At15955_RS00065	COG0616	signal peptide processing
At15955_RS00070	COG0776	regulation of translation
At15955_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
At15955_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
At15955_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
At15955_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
At15955_RS00115	COG0728	peptidoglycan biosynthetic process
At15955_RS00125	COG0180	Tryptophanyl-tRNA synthetase
At15955_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
At15955_RS00140	COG1214	PFAM Peptidase M22, glycoprotease
At15955_RS00145	COG1214	PFAM Peptidase M22, glycoprotease
At15955_RS00145	COG0456	acetyltransferase
At15955_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
At15955_RS00165	COG1702	phosphate starvation-inducible protein PhoH
At15955_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
At15955_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
At15955_RS00185	COG1396	sequence-specific DNA binding
At15955_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
At15955_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
At15955_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At15955_RS00210	COG0242	peptide deformylase activity
At15955_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
At15955_RS00220	COG0101	tRNA pseudouridine synthase activity
At15955_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
At15955_RS00235	COG2171	N-acyltransferase activity
At15955_RS00245	COG0840	transmembrane signaling receptor activity
At15955_RS00255	COG0071	Belongs to the small heat shock protein (HSP20) family
At15955_RS00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
At15955_RS00295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
At15955_RS00300	COG0706	membrane insertase activity
At15955_RS00305	COG0594	ribonuclease P activity
At15955_RS00310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
At15955_RS00320	COG0840	transmembrane signaling receptor activity
At15955_RS00340	COG2226	methyltransferase
At15955_RS00345	COG3842	ATPase activity
At15955_RS00350	COG1175	transmembrane transport
At15955_RS00355	COG0395	ABC-type sugar transport system, permease component
At15955_RS00370	COG0427	acetyl-CoA hydrolase
At15955_RS00380	COG3938	Belongs to the proline racemase family
At15955_RS00385	COG0418	dihydroorotase activity
At15955_RS00390	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
At15955_RS00410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
At15955_RS00415	COG0166	Belongs to the GPI family
At15955_RS00420	COG0318	PFAM AMP-dependent synthetase and ligase
At15955_RS00425	COG3842	ATPase activity
At15955_RS00430	COG1840	ABC-type Fe3 transport system, periplasmic component
At15955_RS00435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
At15955_RS00440	COG4774	siderophore transport
At15955_RS00480	COG2326	polyphosphate kinase activity
At15955_RS00485	COG5002	protein histidine kinase activity
At15955_RS00490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
At15955_RS00495	COG0573	inorganic phosphate transmembrane transporter activity
At15955_RS00505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
At15955_RS00510	COG0704	Plays a role in the regulation of phosphate uptake
At15955_RS00515	COG0745	RESPONSE REGULATOR receiver
At15955_RS00530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
At15955_RS00535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
At15955_RS00545	COG2967	ApaG domain
At15955_RS00555	COG0717	Belongs to the dCTP deaminase family
At15955_RS00565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
At15955_RS00615	COG0167	dihydroorotate dehydrogenase activity
At15955_RS00630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
At15955_RS00650	COG1959	2 iron, 2 sulfur cluster binding
At15955_RS00655	COG1201	RNA secondary structure unwinding
At15955_RS00690	COG1960	acyl-CoA dehydrogenase activity
At15955_RS00695	COG0183	Belongs to the thiolase family
At15955_RS00700	COG1024	Enoyl-CoA hydratase
At15955_RS00700	COG1250	3-hydroxyacyl-CoA dehydrogenase
At15955_RS00720	COG1320	monovalent cation:proton antiporter activity
At15955_RS00725	COG2212	antiporter activity
At15955_RS00730	COG1863	multisubunit Na H antiporter MnhE subunit
At15955_RS00735	COG0651	ATP synthesis coupled electron transport
At15955_RS00740	COG1006	Multisubunit Na H antiporter MnhC subunit
At15955_RS00745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
At15955_RS00745	COG2111	Na H antiporter
At15955_RS00755	COG0840	transmembrane signaling receptor activity
At15955_RS00765	COG0745	RESPONSE REGULATOR receiver
At15955_RS00770	COG2198	Histidine kinase
At15955_RS00770	COG0643	Histidine kinase
At15955_RS00775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
At15955_RS00780	COG2201	protein-glutamate methylesterase activity
At15955_RS00785	COG0745	RESPONSE REGULATOR receiver
At15955_RS00790	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
At15955_RS00800	COG1766	The M ring may be actively involved in energy transduction
At15955_RS00805	COG2771	luxR family
At15955_RS00815	COG2972	Histidine kinase
At15955_RS00815	COG0840	transmembrane signaling receptor activity
At15955_RS00820	COG0784	Response regulator, receiver
At15955_RS00820	COG2198	Histidine kinase
At15955_RS00820	COG2205	protein histidine kinase activity
At15955_RS00825	COG1970	mechanosensitive ion channel activity
At15955_RS00830	COG0436	Aminotransferase
At15955_RS00845	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
At15955_RS00850	COG0424	maF-like protein
At15955_RS00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
At15955_RS00865	COG5328	Belongs to the UPF0262 family
At15955_RS00870	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
At15955_RS00880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
At15955_RS00895	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
At15955_RS00915	COG1338	Plays a role in the flagellum-specific transport system
At15955_RS00925	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
At15955_RS00935	COG1706	bacterial-type flagellum-dependent cell motility
At15955_RS00940	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
At15955_RS00945	COG4786	Flagellar basal body rod
At15955_RS00950	COG1677	Flagellar hook-basal body complex protein FliE
At15955_RS00955	COG1558	bacterial-type flagellum-dependent cell motility
At15955_RS00960	COG1815	bacterial-type flagellum-dependent cell motility
At15955_RS00970	COG1157	protein secretion by the type III secretion system
At15955_RS00975	COG4786	Flagellar basal body rod
At15955_RS00985	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
At15955_RS00990	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
At15955_RS00995	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
At15955_RS01000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
At15955_RS01005	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
At15955_RS01030	COG1749	Flagellar hook protein flgE
At15955_RS01050	COG5443	negative regulation of bacterial-type flagellum assembly
At15955_RS01055	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
At15955_RS01065	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
At15955_RS01105	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
At15955_RS01110	COG1609	Transcriptional regulator
At15955_RS01115	COG1653	transport
At15955_RS01120	COG1175	transmembrane transport
At15955_RS01125	COG0395	ABC-type sugar transport system, permease component
At15955_RS01130	COG0366	Alpha amylase catalytic
At15955_RS01135	COG3842	ATPase activity
At15955_RS01150	COG0129	dihydroxy-acid dehydratase activity
At15955_RS01155	COG0363	glucosamine-6-phosphate deaminase activity
At15955_RS01160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
At15955_RS01170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS01180	COG2081	HI0933 family
At15955_RS01200	COG2224	Isocitrate lyase
At15955_RS01215	COG3842	ATPase activity
At15955_RS01220	COG1176	ABC-type spermidine putrescine transport system, permease component I
At15955_RS01225	COG1177	transmembrane transport
At15955_RS01235	COG2205	protein histidine kinase activity
At15955_RS01250	COG0248	Ppx GppA phosphatase
At15955_RS01255	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
At15955_RS01260	COG0477	Major facilitator Superfamily
At15955_RS01295	COG0521	Mo-molybdopterin cofactor biosynthetic process
At15955_RS01300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
At15955_RS01310	COG0142	geranyltranstransferase activity
At15955_RS01335	COG0752	glycyl-tRNA synthetase alpha subunit
At15955_RS01340	COG1704	LemA family
At15955_RS01345	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
At15955_RS01355	COG0751	glycine-tRNA ligase activity
At15955_RS01370	COG1683	Conserved Protein
At15955_RS01375	COG0840	transmembrane signaling receptor activity
At15955_RS01385	COG0151	Belongs to the GarS family
At15955_RS01390	COG2183	response to ionizing radiation
At15955_RS01395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
At15955_RS01420	COG0583	DNA-binding transcription factor activity
At15955_RS01440	COG0306	phosphate transporter
At15955_RS01455	COG0561	phosphatase activity
At15955_RS01460	COG0438	transferase activity, transferring glycosyl groups
At15955_RS01465	COG2186	Transcriptional regulator
At15955_RS01475	COG0583	DNA-binding transcription factor activity
At15955_RS01480	COG0277	FAD linked oxidase domain protein
At15955_RS01485	COG0277	FAD linked oxidase domain protein
At15955_RS01490	COG0247	lactate metabolic process
At15955_RS01500	COG1376	ErfK ybiS ycfS ynhG family protein
At15955_RS01505	COG2818	Glycosylase
At15955_RS01515	COG2855	membrane
At15955_RS01520	COG0583	DNA-binding transcription factor activity
At15955_RS01540	COG0124	histidyl-tRNA synthetase
At15955_RS01550	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
At15955_RS01555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
At15955_RS01560	COG2259	Doxx family
At15955_RS01570	COG0459	protein refolding
At15955_RS01575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
At15955_RS01585	COG0196	riboflavin kinase activity
At15955_RS01590	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
At15955_RS01600	COG0590	tRNA wobble adenosine to inosine editing
At15955_RS01605	COG1187	pseudouridine synthase activity
At15955_RS01610	COG0742	ribosomal rna small subunit methyltransferase
At15955_RS01615	COG1752	Esterase of the alpha-beta hydrolase superfamily
At15955_RS01625	COG0312	modulator of DNA gyrase
At15955_RS01640	COG1519	Transferase
At15955_RS01650	COG1663	tetraacyldisaccharide 4'-kinase activity
At15955_RS01665	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
At15955_RS01670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS01670	COG2205	protein histidine kinase activity
At15955_RS01675	COG3300	MHYT domain
At15955_RS01675	COG5001	Diguanylate cyclase
At15955_RS01680	COG3386	PFAM SMP-30 Gluconolaconase
At15955_RS01685	COG0800	Aldolase
At15955_RS01690	COG3734	2-keto-3-deoxy-galactonokinase
At15955_RS01695	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS01700	COG1414	Transcriptional regulator
At15955_RS01705	COG2197	response regulator
At15955_RS01720	COG0598	Magnesium transport protein CorA
At15955_RS01725	COG3158	transport of potassium into the cell
At15955_RS01740	COG0356	it plays a direct role in the translocation of protons across the membrane
At15955_RS01750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
At15955_RS01755	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
At15955_RS01765	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
At15955_RS01785	COG0009	L-threonylcarbamoyladenylate synthase
At15955_RS01795	COG4638	Rieske (2fe-2S)
At15955_RS01820	COG1960	acyl-CoA dehydrogenase activity
At15955_RS01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
At15955_RS01840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
At15955_RS01845	COG0840	transmembrane signaling receptor activity
At15955_RS01870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
At15955_RS01875	COG1741	Belongs to the pirin family
At15955_RS01880	COG1722	exodeoxyribonuclease VII activity
At15955_RS01885	COG0123	including yeast histone deacetylase and acetoin utilization protein
At15955_RS01890	COG1268	BioY protein
At15955_RS01895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
At15955_RS01900	COG1122	ATPase activity
At15955_RS01905	COG3214	Protein conserved in bacteria
At15955_RS01910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
At15955_RS01910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
At15955_RS01915	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
At15955_RS01930	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
At15955_RS01935	COG0484	heat shock protein binding
At15955_RS01945	COG0259	pyridoxamine-phosphate oxidase activity
At15955_RS01960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
At15955_RS01970	COG0312	modulator of DNA gyrase
At15955_RS01995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
At15955_RS02000	COG0109	protoheme IX farnesyltransferase activity
At15955_RS02010	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
At15955_RS02025	COG3346	SURF1 family
At15955_RS02030	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
At15955_RS02035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
At15955_RS02040	COG0328	RNA-DNA hybrid ribonuclease activity
At15955_RS02055	COG0678	peroxiredoxin activity
At15955_RS02055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
At15955_RS02065	COG1678	Uncharacterized ACR, COG1678
At15955_RS02085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
At15955_RS02090	COG0612	Peptidase, M16
At15955_RS02105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
At15955_RS02125	COG2189	Belongs to the N(4) N(6)-methyltransferase family
At15955_RS02145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
At15955_RS02150	COG1196	nuclear chromosome segregation
At15955_RS02155	COG2514	catechol 2,3-dioxygenase activity
At15955_RS02160	COG0574	Belongs to the PEP-utilizing enzyme family
At15955_RS02160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
At15955_RS02170	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
At15955_RS02175	COG1823	symporter activity
At15955_RS02200	COG0579	oxidoreductase
At15955_RS02230	COG2895	sulfate adenylyltransferase (ATP) activity
At15955_RS02235	COG0175	sulfate reduction
At15955_RS02240	COG0175	sulfate reduction
At15955_RS02245	COG1959	2 iron, 2 sulfur cluster binding
At15955_RS02250	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
At15955_RS02255	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
At15955_RS02260	COG4208	sulfate ABC transporter
At15955_RS02265	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
At15955_RS02275	COG4943	cyclic-guanylate-specific phosphodiesterase activity
At15955_RS02285	COG1309	transcriptional regulator
At15955_RS02290	COG1012	belongs to the aldehyde dehydrogenase family
At15955_RS02295	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
At15955_RS02335	COG1846	Transcriptional regulator
At15955_RS02340	COG0477	Major facilitator Superfamily
At15955_RS02350	COG1793	dna ligase
At15955_RS02350	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
At15955_RS02365	COG1376	ErfK ybiS ycfS ynhG family protein
At15955_RS02370	COG1376	ErfK ybiS ycfS ynhG family protein
At15955_RS02385	COG1846	Transcriptional regulator
At15955_RS02390	COG1764	response to oxidative stress
At15955_RS02405	COG0488	(ABC) transporter
At15955_RS02440	COG0583	DNA-binding transcription factor activity
At15955_RS02445	COG4221	oxidoreductase activity
At15955_RS02455	COG0433	COG0433 Predicted ATPase
At15955_RS02470	COG1733	regulation of RNA biosynthetic process
At15955_RS02475	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
At15955_RS02485	COG1280	lysine exporter protein (LysE YggA)
At15955_RS02490	COG0656	L-ascorbic acid biosynthetic process
At15955_RS02510	COG4106	trans-aconitate 2-methyltransferase activity
At15955_RS02515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
At15955_RS02520	COG0840	transmembrane signaling receptor activity
At15955_RS02525	COG0583	DNA-binding transcription factor activity
At15955_RS02540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
At15955_RS02560	COG3909	cytochrome
At15955_RS02565	COG2010	Cytochrome c
At15955_RS02595	COG0789	Transcriptional regulator
At15955_RS02610	COG1230	cation diffusion facilitator family transporter
At15955_RS02625	COG4176	ABC-type proline glycine betaine transport system permease component
At15955_RS02650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At15955_RS02660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
At15955_RS02660	COG2169	Transcriptional regulator
At15955_RS02670	COG2514	catechol 2,3-dioxygenase activity
At15955_RS02685	COG1272	protein, Hemolysin III
At15955_RS02695	COG1280	lysine exporter protein (LysE YggA)
At15955_RS02700	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
At15955_RS02705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
At15955_RS02705	COG2111	Na H antiporter
At15955_RS02710	COG2111	Na H antiporter
At15955_RS02715	COG1006	Multisubunit Na H antiporter MnhC subunit
At15955_RS02720	COG0651	ATP synthesis coupled electron transport
At15955_RS02725	COG1863	multisubunit Na H antiporter MnhE subunit
At15955_RS02730	COG2212	antiporter activity
At15955_RS02735	COG1320	monovalent cation:proton antiporter activity
At15955_RS02740	COG4957	zinc ion binding
At15955_RS02755	COG2166	iron-sulfur cluster assembly
At15955_RS02765	COG2205	protein histidine kinase activity
At15955_RS02810	COG0583	DNA-binding transcription factor activity
At15955_RS02820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
At15955_RS02825	COG2983	Belongs to the UPF0260 family
At15955_RS02870	COG1621	beta-fructofuranosidase activity
At15955_RS02875	COG2202	Pas domain
At15955_RS02875	COG3920	Histidine kinase
At15955_RS02880	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
At15955_RS02935	COG4695	Portal protein
At15955_RS03040	COG4235	cytochrome complex assembly
At15955_RS03045	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
At15955_RS03050	COG1138	Cytochrome C-type biogenesis protein
At15955_RS03055	COG3088	subunit of a heme lyase
At15955_RS03060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
At15955_RS03065	COG0745	RESPONSE REGULATOR receiver
At15955_RS03075	COG3011	Protein conserved in bacteria
At15955_RS03085	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
At15955_RS03090	COG2202	Pas domain
At15955_RS03090	COG2205	protein histidine kinase activity
At15955_RS03100	COG0308	aminopeptidase N
At15955_RS03125	COG0443	Heat shock 70 kDa protein
At15955_RS03135	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS03165	COG0604	alcohol dehydrogenase
At15955_RS03170	COG1733	regulation of RNA biosynthetic process
At15955_RS03175	COG1968	undecaprenyl-diphosphatase activity
At15955_RS03180	COG2239	Acts as a magnesium transporter
At15955_RS03185	COG2814	Major facilitator Superfamily
At15955_RS03205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
At15955_RS03230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
At15955_RS03275	COG0741	lytic transglycosylase activity
At15955_RS03280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At15955_RS03285	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
At15955_RS03290	COG0840	transmembrane signaling receptor activity
At15955_RS03300	COG1758	RNA polymerase activity
At15955_RS03320	COG0736	holo-[acyl-carrier-protein] synthase activity
At15955_RS03325	COG0681	Belongs to the peptidase S26 family
At15955_RS03330	COG0571	ribonuclease III activity
At15955_RS03335	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
At15955_RS03340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
At15955_RS03345	COG0784	Response regulator, receiver
At15955_RS03350	COG1381	Involved in DNA repair and RecF pathway recombination
At15955_RS03360	COG2226	methyltransferase
At15955_RS03370	COG1418	mRNA catabolic process
At15955_RS03380	COG0346	lactoylglutathione lyase activity
At15955_RS03395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At15955_RS03400	COG3443	Belongs to the bacterial solute-binding protein 9 family
At15955_RS03405	COG0668	transmembrane transport
At15955_RS03415	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
At15955_RS03420	COG0354	folic acid binding
At15955_RS03445	COG1742	UPF0060 membrane protein
At15955_RS03460	COG1183	phosphatidylcholine synthase activity
At15955_RS03465	COG0688	phosphatidylethanolamine metabolic process
At15955_RS03470	COG5265	(ABC) transporter
At15955_RS03515	COG2852	Protein conserved in bacteria
At15955_RS03520	COG0215	cysteine-tRNA ligase activity
At15955_RS03525	COG4221	oxidoreductase activity
At15955_RS03530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
At15955_RS03535	COG1286	toxin biosynthetic process
At15955_RS03555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
At15955_RS03565	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
At15955_RS03575	COG0305	Participates in initiation and elongation during chromosome replication
At15955_RS03600	COG0359	binds to the 23S rRNA
At15955_RS03610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
At15955_RS03615	COG0360	Binds together with S18 to 16S ribosomal RNA
At15955_RS03625	COG0667	Aldo Keto reductase
At15955_RS03630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
At15955_RS03640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
At15955_RS03645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
At15955_RS03650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
At15955_RS03655	COG1561	YicC-like family, N-terminal region
At15955_RS03660	COG0194	GDP metabolic process
At15955_RS03670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
At15955_RS03675	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
At15955_RS03685	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
At15955_RS03700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
At15955_RS03720	COG3706	GGDEF domain
At15955_RS03720	COG5001	Diguanylate cyclase
At15955_RS03720	COG4251	negative regulation of phosphorylation
At15955_RS03720	COG2203	Gaf domain
At15955_RS03730	COG0488	(ABC) transporter
At15955_RS03735	COG3706	GGDEF domain
At15955_RS03745	COG0105	UTP biosynthetic process
At15955_RS03765	COG0314	molybdopterin synthase activity
At15955_RS03775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
At15955_RS03780	COG0322	excinuclease ABC activity
At15955_RS03785	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS03795	COG0625	glutathione transferase activity
At15955_RS03810	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
At15955_RS03815	COG0243	molybdopterin cofactor binding
At15955_RS03835	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
At15955_RS03840	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
At15955_RS03845	COG0628	permease
At15955_RS03855	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
At15955_RS03860	COG0248	Ppx GppA phosphatase
At15955_RS03865	COG0456	acetyltransferase
At15955_RS03890	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
At15955_RS03900	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
At15955_RS03905	COG0477	Major facilitator Superfamily
At15955_RS03910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
At15955_RS03915	COG4452	Inner membrane protein CreD
At15955_RS03920	COG0659	secondary active sulfate transmembrane transporter activity
At15955_RS03930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
At15955_RS03935	COG3654	unkown
At15955_RS03940	COG2336	PFAM SpoVT AbrB
At15955_RS03945	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
At15955_RS03955	COG0113	porphobilinogen synthase activity
At15955_RS03975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
At15955_RS03980	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
At15955_RS03985	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
At15955_RS03985	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
At15955_RS03995	COG1280	lysine exporter protein (LysE YggA)
At15955_RS04000	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
At15955_RS04005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
At15955_RS04010	COG2814	Major facilitator Superfamily
At15955_RS04015	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
At15955_RS04035	COG0416	fatty acid biosynthetic process
At15955_RS04040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
At15955_RS04045	COG0776	regulation of translation
At15955_RS04080	COG0601	transmembrane transport
At15955_RS04085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS04090	COG0444	Belongs to the ABC transporter superfamily
At15955_RS04110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
At15955_RS04115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
At15955_RS04130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
At15955_RS04135	COG0583	DNA-binding transcription factor activity
At15955_RS04145	COG0737	Belongs to the 5'-nucleotidase family
At15955_RS04170	COG2897	thiosulfate sulfurtransferase activity
At15955_RS04185	COG0415	Belongs to the DNA photolyase family
At15955_RS04195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
At15955_RS04225	COG3932	Exopolysaccharide synthesis, ExoD
At15955_RS04230	COG1238	metal cluster binding
At15955_RS04245	COG4139	cobalamin transport
At15955_RS04250	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
At15955_RS04255	COG3794	PFAM blue (type 1) copper domain protein
At15955_RS04260	COG1528	Iron-storage protein
At15955_RS04330	COG1612	heme a metabolic process
At15955_RS04340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
At15955_RS04345	COG0010	Belongs to the arginase family
At15955_RS04350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
At15955_RS04355	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
At15955_RS04365	COG1832	CoA-binding protein
At15955_RS04380	COG2124	cytochrome p450
At15955_RS04385	COG2199	diguanylate cyclase activity
At15955_RS04390	COG0740	serine-type endopeptidase activity
At15955_RS04395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
At15955_RS04405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
At15955_RS04415	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
At15955_RS04440	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
At15955_RS04445	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
At15955_RS04450	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
At15955_RS04460	COG0649	NAD binding
At15955_RS04470	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
At15955_RS04475	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
At15955_RS04485	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
At15955_RS04490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
At15955_RS04500	COG0713	ATP synthesis coupled electron transport
At15955_RS04515	COG1007	ATP synthesis coupled electron transport
At15955_RS04520	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
At15955_RS04520	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
At15955_RS04535	COG0442	prolyl-tRNA aminoacylation
At15955_RS04545	COG1136	(ABC) transporter
At15955_RS04565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
At15955_RS04575	COG0784	Response regulator, receiver
At15955_RS04585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
At15955_RS04590	COG0477	Major facilitator Superfamily
At15955_RS04605	COG0557	exoribonuclease II activity
At15955_RS04610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
At15955_RS04620	COG0758	DNA mediated transformation
At15955_RS04625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
At15955_RS04635	COG0540	Belongs to the ATCase OTCase family
At15955_RS04640	COG1960	acyl-CoA dehydrogenase activity
At15955_RS04645	COG0456	acetyltransferase
At15955_RS04660	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
At15955_RS04665	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
At15955_RS04670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
At15955_RS04675	COG0154	amidase activity
At15955_RS04680	COG3811	Belongs to the UPF0386 family
At15955_RS04695	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
At15955_RS04705	COG0456	acetyltransferase
At15955_RS04720	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
At15955_RS04730	COG0511	ligase activity, forming carbon-carbon bonds
At15955_RS04735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
At15955_RS04745	COG0436	Aminotransferase
At15955_RS04765	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS04770	COG1530	ribonuclease E activity
At15955_RS04785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
At15955_RS04805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
At15955_RS04810	COG0384	phenazine biosynthesis protein PhzF
At15955_RS04825	COG0633	Ferredoxin
At15955_RS04840	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
At15955_RS04845	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
At15955_RS04855	COG3768	UPF0283 membrane protein
At15955_RS04860	COG3106	COG3106 Predicted ATPase
At15955_RS04890	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
At15955_RS04930	COG0537	adenosine 5'-monophosphoramidase activity
At15955_RS04955	COG0052	Belongs to the universal ribosomal protein uS2 family
At15955_RS04960	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
At15955_RS04965	COG0528	UMP kinase activity
At15955_RS04970	COG0233	cytoplasmic translational termination
At15955_RS04975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
At15955_RS04985	COG0750	zinc metalloprotease
At15955_RS04990	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
At15955_RS04995	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
At15955_RS05000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
At15955_RS05005	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
At15955_RS05010	COG3494	Protein of unknown function (DUF1009)
At15955_RS05015	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
At15955_RS05020	COG0372	Belongs to the citrate synthase family
At15955_RS05035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
At15955_RS05045	COG2877	3-deoxy-8-phosphooctulonate synthase activity
At15955_RS05050	COG0148	phosphopyruvate hydratase activity
At15955_RS05060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
At15955_RS05065	COG0022	dehydrogenase e1 component
At15955_RS05065	COG0508	dehydrogenase complex catalyzes the overall conversion of
At15955_RS05070	COG0508	dehydrogenase complex catalyzes the overall conversion of
At15955_RS05080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
At15955_RS05090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
At15955_RS05095	COG0697	spore germination
At15955_RS05110	COG2867	negative regulation of translational initiation
At15955_RS05120	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
At15955_RS05120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
At15955_RS05130	COG3852	Histidine kinase
At15955_RS05135	COG2204	response regulator
At15955_RS05140	COG5000	phosphorelay sensor kinase activity
At15955_RS05145	COG2204	response regulator
At15955_RS05150	COG0569	domain protein
At15955_RS05155	COG1923	regulation of RNA biosynthetic process
At15955_RS05160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
At15955_RS05165	COG3956	TIGRFAM MazG family protein
At15955_RS05175	COG1648	precorrin-2 dehydrogenase activity
At15955_RS05175	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
At15955_RS05215	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
At15955_RS05215	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
At15955_RS05220	COG0509	glycine decarboxylation via glycine cleavage system
At15955_RS05225	COG0404	The glycine cleavage system catalyzes the degradation of glycine
At15955_RS05255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
At15955_RS05260	COG0564	pseudouridine synthase activity
At15955_RS05285	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
At15955_RS05295	COG1671	Belongs to the UPF0178 family
At15955_RS05305	COG0450	alkyl hydroperoxide reductase
At15955_RS05310	COG0625	glutathione transferase activity
At15955_RS05350	COG2801	Transposase and inactivated derivatives
At15955_RS05355	COG0583	DNA-binding transcription factor activity
At15955_RS05360	COG2828	Protein conserved in bacteria
At15955_RS05375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At15955_RS05380	COG4191	Histidine kinase
At15955_RS05380	COG0784	Response regulator, receiver
At15955_RS05385	COG0784	Response regulator, receiver
At15955_RS05390	COG2202	Pas domain
At15955_RS05390	COG3920	Histidine kinase
At15955_RS05395	COG0784	Response regulator, receiver
At15955_RS05395	COG4191	Histidine kinase
At15955_RS05425	COG0673	inositol 2-dehydrogenase activity
At15955_RS05435	COG1609	Transcriptional regulator
At15955_RS05440	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS05445	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS05450	COG1129	ABC transporter
At15955_RS05455	COG1879	ABC-type sugar transport system periplasmic component
At15955_RS05460	COG0328	RNA-DNA hybrid ribonuclease activity
At15955_RS05470	COG2226	methyltransferase
At15955_RS05480	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
At15955_RS05480	COG0321	lipoyl(octanoyl) transferase activity
At15955_RS05485	COG0084	hydrolase, TatD family'
At15955_RS05490	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
At15955_RS05500	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
At15955_RS05555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
At15955_RS05560	COG2095	MarC family integral membrane protein
At15955_RS05565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
At15955_RS05565	COG0517	IMP dehydrogenase activity
At15955_RS05565	COG0617	tRNA 3'-terminal CCA addition
At15955_RS05570	COG0629	single-stranded DNA binding
At15955_RS05575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
At15955_RS05585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
At15955_RS05590	COG0179	Fumarylacetoacetate (FAA) hydrolase
At15955_RS05605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
At15955_RS05610	COG1121	(ABC) transporter
At15955_RS05630	COG0667	Aldo Keto reductase
At15955_RS05640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
At15955_RS05715	COG2239	Acts as a magnesium transporter
At15955_RS05720	COG0243	molybdopterin cofactor binding
At15955_RS05730	COG0242	peptide deformylase activity
At15955_RS05760	COG0321	lipoyl(octanoyl) transferase activity
At15955_RS05765	COG1064	alcohol dehydrogenase
At15955_RS05795	COG1862	Preprotein translocase
At15955_RS05815	COG2124	cytochrome p450
At15955_RS05830	COG0596	Alpha beta hydrolase
At15955_RS05840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
At15955_RS05845	COG0626	cystathionine gamma-synthase activity
At15955_RS05850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS05855	COG4597	amino acid ABC transporter
At15955_RS05860	COG0765	amino acid transport
At15955_RS05865	COG1126	abc transporter atp-binding protein
At15955_RS05885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
At15955_RS05900	COG0436	Aminotransferase
At15955_RS05930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
At15955_RS05945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
At15955_RS05950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
At15955_RS05955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
At15955_RS05970	COG3243	poly(R)-hydroxyalkanoic acid synthase
At15955_RS05975	COG1489	DNA binding
At15955_RS05980	COG0024	Methionine aminopeptidase
At15955_RS05985	COG2003	Belongs to the UPF0758 family
At15955_RS06000	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
At15955_RS06015	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
At15955_RS06020	COG0546	phosphoglycolate phosphatase activity
At15955_RS06030	COG0114	fumarate hydratase activity
At15955_RS06040	COG0504	CTP synthase activity
At15955_RS06050	COG0149	triose-phosphate isomerase activity
At15955_RS06060	COG0187	DNA topoisomerase II activity
At15955_RS06065	COG0740	serine-type endopeptidase activity
At15955_RS06075	COG0640	Transcriptional regulator
At15955_RS06080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
At15955_RS06085	COG0745	RESPONSE REGULATOR receiver
At15955_RS06105	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
At15955_RS06105	COG3264	Mechanosensitive ion channel
At15955_RS06175	COG1127	ABC transporter
At15955_RS06180	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
At15955_RS06185	COG4948	Mandelate Racemase Muconate Lactonizing
At15955_RS06195	COG0281	malic enzyme
At15955_RS06195	COG0280	phosphate acetyltransferase
At15955_RS06205	COG0778	Nitroreductase
At15955_RS06210	COG0823	Involved in the tonB-independent uptake of proteins
At15955_RS06230	COG1368	sulfuric ester hydrolase activity
At15955_RS06260	COG0544	peptidyl-prolyl cis-trans isomerase activity
At15955_RS06285	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
At15955_RS06310	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
At15955_RS06345	COG0512	Glutamine amidotransferase of anthranilate synthase
At15955_RS06345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
At15955_RS06350	COG0343	queuine tRNA-ribosyltransferase activity
At15955_RS06355	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
At15955_RS06370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
At15955_RS06395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
At15955_RS06400	COG0134	indole-3-glycerol-phosphate synthase activity
At15955_RS06405	COG0315	cyclic pyranopterin monophosphate synthase activity
At15955_RS06410	COG0303	'Molybdopterin
At15955_RS06415	COG3706	GGDEF domain
At15955_RS06425	COG0475	glutathione-regulated potassium exporter activity
At15955_RS06425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
At15955_RS06435	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
At15955_RS06440	COG0697	spore germination
At15955_RS06445	COG2814	Major facilitator Superfamily
At15955_RS06450	COG0746	molybdenum cofactor guanylyltransferase activity
At15955_RS06455	COG1763	Mo-molybdopterin cofactor biosynthetic process
At15955_RS06460	COG0739	heme binding
At15955_RS06465	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
At15955_RS06470	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
At15955_RS06475	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
At15955_RS06480	COG0805	protein transport
At15955_RS06485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
At15955_RS06490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
At15955_RS06495	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
At15955_RS06500	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
At15955_RS06505	COG1472	Belongs to the glycosyl hydrolase 3 family
At15955_RS06515	COG0018	arginyl-trna synthetase
At15955_RS06520	COG0232	Belongs to the dGTPase family. Type 2 subfamily
At15955_RS06525	COG0316	Belongs to the HesB IscA family
At15955_RS06550	COG0525	valine-tRNA ligase activity
At15955_RS06560	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
At15955_RS06595	COG0655	NAD(P)H dehydrogenase (quinone) activity
At15955_RS06600	COG1058	Belongs to the CinA family
At15955_RS06600	COG1546	Belongs to the CinA family
At15955_RS06605	COG0589	response to stress
At15955_RS06610	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
At15955_RS06620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
At15955_RS06645	COG1132	(ABC) transporter
At15955_RS06650	COG0628	permease
At15955_RS06685	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
At15955_RS06695	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
At15955_RS06705	COG0302	gtp cyclohydrolase
At15955_RS06710	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
At15955_RS06715	COG1752	Esterase of the alpha-beta hydrolase superfamily
At15955_RS06720	COG0516	GMP reductase activity
At15955_RS06720	COG0517	IMP dehydrogenase activity
At15955_RS06755	COG1760	l-serine dehydratase
At15955_RS06790	COG0583	DNA-binding transcription factor activity
At15955_RS06805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
At15955_RS06805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
At15955_RS06810	COG0347	Belongs to the P(II) protein family
At15955_RS06815	COG0174	glutamine synthetase
At15955_RS06845	COG0697	spore germination
At15955_RS06855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
At15955_RS06865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
At15955_RS06895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
At15955_RS06900	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
At15955_RS06905	COG2186	Transcriptional regulator
At15955_RS06915	COG1079	Belongs to the binding-protein-dependent transport system permease family
At15955_RS06920	COG4603	Belongs to the binding-protein-dependent transport system permease family
At15955_RS06925	COG3845	ABC transporter
At15955_RS06930	COG1183	phosphatidylcholine synthase activity
At15955_RS06935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
At15955_RS06940	COG0679	Auxin Efflux Carrier
At15955_RS06945	COG0785	Cytochrome C biogenesis protein
At15955_RS06975	COG0346	lactoylglutathione lyase activity
At15955_RS06980	COG1278	Cold shock
At15955_RS07040	COG1136	(ABC) transporter
At15955_RS07040	COG0577	efflux transmembrane transporter activity
At15955_RS07045	COG0577	efflux transmembrane transporter activity
At15955_RS07045	COG1136	(ABC) transporter
At15955_RS07060	COG2151	metal-sulfur cluster biosynthetic enzyme
At15955_RS07065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
At15955_RS07070	COG0719	Fe-S assembly protein
At15955_RS07075	COG0396	ATPase activity
At15955_RS07080	COG0719	Fe-S assembly protein
At15955_RS07085	COG1104	cysteine desulfurase activity
At15955_RS07090	COG2945	thiolester hydrolase activity
At15955_RS07095	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
At15955_RS07100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
At15955_RS07110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
At15955_RS07115	COG2833	Protein of unknown function (DUF455)
At15955_RS07120	COG0739	heme binding
At15955_RS07125	COG0513	Belongs to the DEAD box helicase family
At15955_RS07150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
At15955_RS07160	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
At15955_RS07165	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
At15955_RS07170	COG0047	phosphoribosylformylglycinamidine synthase activity
At15955_RS07185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
At15955_RS07195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
At15955_RS07220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
At15955_RS07225	COG2814	Major facilitator Superfamily
At15955_RS07230	COG0483	inositol monophosphate 1-phosphatase activity
At15955_RS07235	COG0483	inositol monophosphate 1-phosphatase activity
At15955_RS07240	COG0037	tRNA processing
At15955_RS07245	COG2066	Belongs to the glutaminase family
At15955_RS07250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
At15955_RS07255	COG0861	Integral membrane protein TerC family
At15955_RS07275	COG1280	lysine exporter protein (LysE YggA)
At15955_RS07290	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
At15955_RS07295	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
At15955_RS07305	COG0538	isocitrate dehydrogenase activity
At15955_RS07320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
At15955_RS07325	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
At15955_RS07330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At15955_RS07335	COG2313	pseudouridylate synthase activity
At15955_RS07350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS07355	COG4215	(ABC) transporter
At15955_RS07365	COG5425	PFAM Usg family protein
At15955_RS07375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At15955_RS07380	COG1522	sequence-specific DNA binding
At15955_RS07385	COG1573	uracil-dna glycosylase
At15955_RS07395	COG2202	Pas domain
At15955_RS07395	COG2205	protein histidine kinase activity
At15955_RS07405	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
At15955_RS07410	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
At15955_RS07425	COG0842	Transport permease protein
At15955_RS07430	COG1131	(ABC) transporter
At15955_RS07435	COG0730	response to heat
At15955_RS07450	COG0840	transmembrane signaling receptor activity
At15955_RS07450	COG0840	transmembrane signaling receptor activity
At15955_RS07460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
At15955_RS07465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
At15955_RS07480	COG0129	dihydroxy-acid dehydratase activity
At15955_RS07485	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
At15955_RS07490	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
At15955_RS07500	COG3739	integral membrane protein
At15955_RS07510	COG0203	ribosomal protein L17
At15955_RS07515	COG0202	RNA polymerase activity
At15955_RS07520	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
At15955_RS07525	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
At15955_RS07530	COG0563	adenylate kinase activity
At15955_RS07535	COG0201	protein transport
At15955_RS07540	COG0200	Binds to the 23S rRNA
At15955_RS07545	COG1841	ribosomal large subunit assembly
At15955_RS07550	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
At15955_RS07555	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
At15955_RS07560	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
At15955_RS07565	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
At15955_RS07570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
At15955_RS07575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
At15955_RS07580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
At15955_RS07585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
At15955_RS07590	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
At15955_RS07595	COG0255	Belongs to the universal ribosomal protein uL29 family
At15955_RS07600	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
At15955_RS07605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
At15955_RS07610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
At15955_RS07615	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
At15955_RS07620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
At15955_RS07625	COG0089	rRNA binding
At15955_RS07630	COG0088	Forms part of the polypeptide exit tunnel
At15955_RS07635	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
At15955_RS07640	COG0051	transcription antitermination factor activity, RNA binding
At15955_RS07645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
At15955_RS07650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
At15955_RS07655	COG0049	tRNA binding
At15955_RS07660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
At15955_RS07675	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
At15955_RS07680	COG0085	RNA polymerase activity
At15955_RS07685	COG0222	ribosome binding
At15955_RS07690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
At15955_RS07695	COG0081	regulation of translation
At15955_RS07700	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
At15955_RS07710	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
At15955_RS07725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
At15955_RS07730	COG0861	Integral membrane protein TerC family
At15955_RS07765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
At15955_RS07770	COG1607	acyl-coa hydrolase
At15955_RS07795	COG2910	NAD(P)H-binding
At15955_RS07800	COG1733	regulation of RNA biosynthetic process
At15955_RS07810	COG0556	nucleotide-excision repair
At15955_RS07840	COG0484	heat shock protein binding
At15955_RS07865	COG3842	ATPase activity
At15955_RS07875	COG1840	ABC-type Fe3 transport system, periplasmic component
At15955_RS07885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
At15955_RS07900	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
At15955_RS07910	COG2207	Transcriptional regulator
At15955_RS07915	COG1064	alcohol dehydrogenase
At15955_RS07920	COG1252	NADH dehydrogenase
At15955_RS07925	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
At15955_RS07930	COG2197	response regulator
At15955_RS07935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
At15955_RS07940	COG1090	epimerase
At15955_RS07980	COG0656	L-ascorbic acid biosynthetic process
At15955_RS07995	COG0440	acetolactate synthase activity
At15955_RS08000	COG0028	Belongs to the TPP enzyme family
At15955_RS08010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
At15955_RS08015	COG3830	Belongs to the UPF0237 family
At15955_RS08015	COG0560	Phosphoserine phosphatase
At15955_RS08025	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS08035	COG0330	HflC and HflK could
At15955_RS08040	COG0330	HflC and HflK could
At15955_RS08050	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
At15955_RS08090	COG0277	FAD linked oxidase domain protein
At15955_RS08100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
At15955_RS08155	COG1335	isochorismatase
At15955_RS08175	COG0006	proline dipeptidase activity
At15955_RS08185	COG2264	protein methyltransferase activity
At15955_RS08190	COG1999	signal sequence binding
At15955_RS08200	COG0835	chemotaxis
At15955_RS08210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
At15955_RS08215	COG0583	DNA-binding transcription factor activity
At15955_RS08225	COG1247	-acetyltransferase
At15955_RS08235	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
At15955_RS08240	COG1280	lysine exporter protein (LysE YggA)
At15955_RS08250	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
At15955_RS08260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
At15955_RS08265	COG0849	cell division
At15955_RS08270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
At15955_RS08275	COG1181	Belongs to the D-alanine--D-alanine ligase family
At15955_RS08280	COG0477	Major facilitator Superfamily
At15955_RS08290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
At15955_RS08295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
At15955_RS08300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
At15955_RS08310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
At15955_RS08315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
At15955_RS08325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
At15955_RS08340	COG0275	rRNA processing
At15955_RS08345	COG2001	Belongs to the MraZ family
At15955_RS08355	COG3766	membrane
At15955_RS08365	COG0754	glutathionylspermidine amidase activity
At15955_RS08390	COG3023	N-Acetylmuramoyl-L-alanine amidase
At15955_RS08420	COG4106	trans-aconitate 2-methyltransferase activity
At15955_RS08440	COG2226	methyltransferase
At15955_RS08450	COG2267	carboxylic ester hydrolase activity
At15955_RS08455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
At15955_RS08470	COG0251	oxidation-reduction process
At15955_RS08485	COG1376	ErfK ybiS ycfS ynhG family protein
At15955_RS08490	COG2814	Major facilitator Superfamily
At15955_RS08515	COG1012	belongs to the aldehyde dehydrogenase family
At15955_RS08520	COG0174	glutamine synthetase
At15955_RS08525	COG0531	amino acid
At15955_RS08535	COG1737	Transcriptional regulator
At15955_RS08560	COG3842	ATPase activity
At15955_RS08620	COG2968	Membrane
At15955_RS08630	COG0432	Pfam Uncharacterised protein family UPF0047
At15955_RS08645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
At15955_RS08650	COG0358	DNA primase activity
At15955_RS08665	COG0505	Belongs to the CarA family
At15955_RS08670	COG0534	Mate efflux family protein
At15955_RS08685	COG2321	neutral zinc metallopeptidase
At15955_RS08700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
At15955_RS08705	COG3706	GGDEF domain
At15955_RS08710	COG1573	uracil-dna glycosylase
At15955_RS08720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
At15955_RS08730	COG1522	sequence-specific DNA binding
At15955_RS08735	COG0492	ferredoxin-NADP+ reductase activity
At15955_RS08740	COG0583	DNA-binding transcription factor activity
At15955_RS08750	COG1902	pentaerythritol trinitrate reductase activity
At15955_RS08780	COG0387	Pfam Sodium calcium exchanger
At15955_RS08785	COG0436	Aminotransferase
At15955_RS08790	COG2200	EAL domain
At15955_RS08790	COG2199	diguanylate cyclase activity
At15955_RS08810	COG1278	Cold shock
At15955_RS08815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
At15955_RS08830	COG1846	Transcriptional regulator
At15955_RS08835	COG0745	RESPONSE REGULATOR receiver
At15955_RS08840	COG2205	protein histidine kinase activity
At15955_RS08845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
At15955_RS08865	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
At15955_RS08875	COG1496	oxidoreductase activity
At15955_RS08890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
At15955_RS08900	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
At15955_RS08915	COG0840	transmembrane signaling receptor activity
At15955_RS08920	COG1012	belongs to the aldehyde dehydrogenase family
At15955_RS08930	COG3300	MHYT domain
At15955_RS08930	COG5001	Diguanylate cyclase
At15955_RS08935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
At15955_RS08940	COG5001	Diguanylate cyclase
At15955_RS08950	COG0193	aminoacyl-tRNA hydrolase activity
At15955_RS08960	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
At15955_RS08980	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
At15955_RS08985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
At15955_RS08995	COG2857	Cytochrome c1
At15955_RS08995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
At15955_RS09020	COG1132	(ABC) transporter
At15955_RS09025	COG1132	(ABC) transporter
At15955_RS09030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
At15955_RS09045	COG0408	coproporphyrinogen oxidase activity
At15955_RS09060	COG0617	tRNA 3'-terminal CCA addition
At15955_RS09075	COG0714	Associated with various cellular activities
At15955_RS09095	COG0454	-acetyltransferase
At15955_RS09100	COG0477	Major facilitator Superfamily
At15955_RS09110	COG0435	Glutathione S-transferase
At15955_RS09130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
At15955_RS09135	COG3135	benzoate transporter
At15955_RS09140	COG4944	Protein of unknown function (DUF1109)
At15955_RS09155	COG0740	serine-type endopeptidase activity
At15955_RS09170	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
At15955_RS09175	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
At15955_RS09205	COG4175	Glycine betaine
At15955_RS09220	COG1435	thymidine kinase activity
At15955_RS09240	COG2862	Uncharacterized protein family, UPF0114
At15955_RS09255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
At15955_RS09255	COG0512	Glutamine amidotransferase of anthranilate synthase
At15955_RS09265	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
At15955_RS09280	COG0366	Alpha amylase catalytic
At15955_RS09285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At15955_RS09300	COG1160	GTP binding
At15955_RS09320	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
At15955_RS09330	COG0024	Methionine aminopeptidase
At15955_RS09345	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS09355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
At15955_RS09365	COG0583	DNA-binding transcription factor activity
At15955_RS09380	COG0402	S-adenosylhomocysteine deaminase activity
At15955_RS09410	COG1309	transcriptional regulator
At15955_RS09415	COG1686	Belongs to the peptidase S11 family
At15955_RS09425	COG2351	hydroxyisourate hydrolase activity
At15955_RS09430	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
At15955_RS09455	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
At15955_RS09465	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
At15955_RS09465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS09470	COG2205	protein histidine kinase activity
At15955_RS09470	COG0784	Response regulator, receiver
At15955_RS09470	COG5002	protein histidine kinase activity
At15955_RS09475	COG0513	Belongs to the DEAD box helicase family
At15955_RS09485	COG2259	Doxx family
At15955_RS09490	COG1376	ErfK ybiS ycfS ynhG family protein
At15955_RS09500	COG2308	Evidence 4 Homologs of previously reported genes of
At15955_RS09510	COG1305	Transglutaminase-like
At15955_RS09530	COG0588	phosphoglycerate mutase activity
At15955_RS09540	COG4214	carbohydrate transport
At15955_RS09550	COG4213	ABC transporter substrate-binding protein
At15955_RS09590	COG0840	transmembrane signaling receptor activity
At15955_RS09610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS09640	COG1215	transferase activity, transferring glycosyl groups
At15955_RS09655	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
At15955_RS09675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
At15955_RS09680	COG2346	COG2346, Truncated hemoglobins
At15955_RS09700	COG1309	transcriptional regulator
At15955_RS09715	COG0494	nUDIX hydrolase
At15955_RS09730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At15955_RS09735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At15955_RS09765	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
At15955_RS09770	COG0830	nickel cation binding
At15955_RS09775	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
At15955_RS09790	COG0804	urea catabolic process
At15955_RS09795	COG1442	glycosyl transferase family 8
At15955_RS09800	COG3755	Protein conserved in bacteria
At15955_RS09810	COG0832	Belongs to the urease beta subunit family
At15955_RS09815	COG3813	Protein conserved in bacteria
At15955_RS09820	COG0831	urea catabolic process
At15955_RS09825	COG0829	nickel cation binding
At15955_RS09840	COG0411	ABC transporter
At15955_RS09850	COG0559	Belongs to the binding-protein-dependent transport system permease family
At15955_RS09870	COG0174	glutamine synthetase
At15955_RS09875	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS09880	COG0784	Response regulator, receiver
At15955_RS09880	COG2198	Histidine kinase
At15955_RS09880	COG5002	protein histidine kinase activity
At15955_RS09925	COG1218	3'(2'),5'-bisphosphate nucleotidase
At15955_RS10005	COG0564	pseudouridine synthase activity
At15955_RS10020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
At15955_RS10030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
At15955_RS10060	COG0346	lactoylglutathione lyase activity
At15955_RS10070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
At15955_RS10080	COG2832	Protein of unknown function (DUF454)
At15955_RS10085	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
At15955_RS10090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS10095	COG4558	Periplasmic binding protein
At15955_RS10105	COG3721	Heme iron utilization protein
At15955_RS10130	COG2205	protein histidine kinase activity
At15955_RS10170	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS10175	COG4605	iron ion homeostasis
At15955_RS10180	COG4604	ABC transporter, ATP-binding protein
At15955_RS10185	COG0783	Belongs to the Dps family
At15955_RS10205	COG0840	transmembrane signaling receptor activity
At15955_RS10205	COG2972	Histidine kinase
At15955_RS10210	COG0656	L-ascorbic acid biosynthetic process
At15955_RS10215	COG2814	Major facilitator Superfamily
At15955_RS10225	COG0583	DNA-binding transcription factor activity
At15955_RS10230	COG0657	acetylesterase activity
At15955_RS10235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At15955_RS10255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
At15955_RS10260	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
At15955_RS10265	COG0288	reversible hydration of carbon dioxide
At15955_RS10275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
At15955_RS10295	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
At15955_RS10300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
At15955_RS10305	COG0778	Nitroreductase
At15955_RS10310	COG2267	carboxylic ester hydrolase activity
At15955_RS10315	COG0251	oxidation-reduction process
At15955_RS10320	COG1335	isochorismatase
At15955_RS10325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS10335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At15955_RS10350	COG1175	transmembrane transport
At15955_RS10355	COG0395	ABC-type sugar transport system, permease component
At15955_RS10360	COG3842	ATPase activity
At15955_RS10365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At15955_RS10375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
At15955_RS10390	COG4608	Belongs to the ABC transporter superfamily
At15955_RS10395	COG0444	Belongs to the ABC transporter superfamily
At15955_RS10400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS10405	COG0601	transmembrane transport
At15955_RS10425	COG0392	lysyltransferase activity
At15955_RS10425	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
At15955_RS10465	COG2159	amidohydrolase
At15955_RS10470	COG1960	acyl-CoA dehydrogenase activity
At15955_RS10495	COG0745	RESPONSE REGULATOR receiver
At15955_RS10505	COG1902	pentaerythritol trinitrate reductase activity
At15955_RS10505	COG0446	pyridine nucleotide-disulphide oxidoreductase
At15955_RS10510	COG3842	ATPase activity
At15955_RS10520	COG1840	ABC-type Fe3 transport system, periplasmic component
At15955_RS10525	COG1840	ABC-type Fe3 transport system, periplasmic component
At15955_RS10545	COG1192	Involved in chromosome partitioning
At15955_RS10550	COG2201	protein-glutamate methylesterase activity
At15955_RS10555	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
At15955_RS10560	COG0835	chemotaxis
At15955_RS10565	COG0840	transmembrane signaling receptor activity
At15955_RS10570	COG0835	chemotaxis
At15955_RS10575	COG2198	Histidine kinase
At15955_RS10575	COG0643	Histidine kinase
At15955_RS10640	COG0277	FAD linked oxidase domain protein
At15955_RS10650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
At15955_RS10650	COG1017	nitric oxide dioxygenase activity
At15955_RS10695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
At15955_RS10705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At15955_RS10710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
At15955_RS10720	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
At15955_RS10745	COG0583	DNA-binding transcription factor activity
At15955_RS10750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS10755	COG0725	ABC transporter, periplasmic molybdate-binding protein
At15955_RS10760	COG4149	molybdate abc transporter
At15955_RS10765	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
At15955_RS10775	COG2022	thiamine diphosphate biosynthetic process
At15955_RS10790	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
At15955_RS10795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
At15955_RS10805	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
At15955_RS10825	COG1132	(ABC) transporter
At15955_RS10830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
At15955_RS10855	COG0438	transferase activity, transferring glycosyl groups
At15955_RS10875	COG4166	transmembrane transport
At15955_RS10880	COG0601	transmembrane transport
At15955_RS10885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS10900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
At15955_RS10905	COG3142	Participates in the control of copper homeostasis
At15955_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS10930	COG1737	Transcriptional regulator
At15955_RS10940	COG3842	ATPase activity
At15955_RS10950	COG0395	ABC-type sugar transport system, permease component
At15955_RS10970	COG2188	Transcriptional regulator
At15955_RS10975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
At15955_RS10980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
At15955_RS10985	COG1940	carbohydrate kinase activity
At15955_RS10995	COG0671	phosphoesterase, PA-phosphatase related
At15955_RS11000	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
At15955_RS11005	COG0156	8-amino-7-oxononanoate synthase activity
At15955_RS11015	COG0729	surface antigen
At15955_RS11025	COG0835	chemotaxis
At15955_RS11035	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
At15955_RS11040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
At15955_RS11045	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
At15955_RS11050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
At15955_RS11055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
At15955_RS11060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
At15955_RS11075	COG4974	Belongs to the 'phage' integrase family
At15955_RS11100	COG1280	lysine exporter protein (LysE YggA)
At15955_RS11110	COG0508	dehydrogenase complex catalyzes the overall conversion of
At15955_RS11115	COG0567	Dehydrogenase, E1 component
At15955_RS11120	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
At15955_RS11125	COG0045	succinate-CoA ligase (ADP-forming) activity
At15955_RS11130	COG0039	L-malate dehydrogenase activity
At15955_RS11135	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
At15955_RS11170	COG2264	protein methyltransferase activity
At15955_RS11185	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
At15955_RS11190	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
At15955_RS11195	COG0181	hydroxymethylbilane synthase activity
At15955_RS11235	COG1872	DUF167
At15955_RS11240	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
At15955_RS11250	COG1217	gtp-binding protein TYPA
At15955_RS11255	COG0339	signal peptide processing
At15955_RS11265	COG1846	Transcriptional regulator
At15955_RS11275	COG0137	argininosuccinate synthase activity
At15955_RS11285	COG1280	lysine exporter protein (LysE YggA)
At15955_RS11290	COG1122	ATPase activity
At15955_RS11295	COG4120	Belongs to the binding-protein-dependent transport system permease family
At15955_RS11305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
At15955_RS11320	COG2154	pterin-4-alpha-carbinolamine dehydratase
At15955_RS11325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
At15955_RS11330	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
At15955_RS11340	COG4181	ATPase activity
At15955_RS11350	COG0670	Belongs to the BI1 family
At15955_RS11365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
At15955_RS11370	COG4133	protoheme IX ABC transporter activity
At15955_RS11375	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
At15955_RS11380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
At15955_RS11405	COG2917	probably involved in intracellular septation
At15955_RS11410	COG0552	protein localization to endoplasmic reticulum
At15955_RS11415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
At15955_RS11420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
At15955_RS11435	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
At15955_RS11440	COG0287	Prephenate dehydrogenase
At15955_RS11440	COG1605	Chorismate mutase
At15955_RS11445	COG0228	four-way junction DNA binding
At15955_RS11450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
At15955_RS11455	COG0336	Belongs to the RNA methyltransferase TrmD family
At15955_RS11465	COG0335	large ribosomal subunit rRNA binding
At15955_RS11470	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
At15955_RS11475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At15955_RS11495	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
At15955_RS11510	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
At15955_RS11530	COG0488	(ABC) transporter
At15955_RS11540	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
At15955_RS11550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
At15955_RS11555	COG0142	geranyltranstransferase activity
At15955_RS11560	COG2885	chlorophyll binding
At15955_RS11565	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
At15955_RS11570	COG2223	nitrite transmembrane transporter activity
At15955_RS11575	COG1349	DNA-binding transcription factor activity
At15955_RS11580	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
At15955_RS11590	COG1132	(ABC) transporter
At15955_RS11600	COG3459	Glycosyltransferase 36 associated
At15955_RS11605	COG1473	amidohydrolase
At15955_RS11615	COG0579	oxidoreductase
At15955_RS11625	COG0129	dihydroxy-acid dehydratase activity
At15955_RS11630	COG2084	Dehydrogenase
At15955_RS11635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At15955_RS11640	COG0277	FAD linked oxidase domain protein
At15955_RS11645	COG2186	Transcriptional regulator
At15955_RS11655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
At15955_RS11660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
At15955_RS11665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
At15955_RS11670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
At15955_RS11685	COG0495	leucyl-tRNA aminoacylation
At15955_RS11700	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
At15955_RS11705	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
At15955_RS11720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
At15955_RS11725	COG1946	Acyl-CoA thioesterase
At15955_RS11730	COG0347	Belongs to the P(II) protein family
At15955_RS11735	COG0004	ammonium transporteR
At15955_RS11740	COG1674	ftsk spoiiie
At15955_RS11745	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
At15955_RS11760	COG0745	RESPONSE REGULATOR receiver
At15955_RS11770	COG1329	Transcriptional regulator
At15955_RS11775	COG2902	Dehydrogenase
At15955_RS11780	COG2270	Major facilitator Superfamily
At15955_RS11795	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS11810	COG0494	nUDIX hydrolase
At15955_RS11820	COG0793	Belongs to the peptidase S41A family
At15955_RS11830	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
At15955_RS11835	COG0799	negative regulation of ribosome biogenesis
At15955_RS11840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
At15955_RS11845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
At15955_RS11850	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
At15955_RS11855	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
At15955_RS11870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
At15955_RS11875	COG0261	This protein binds to 23S rRNA in the presence of protein L20
At15955_RS11900	COG0066	3-isopropylmalate dehydratase activity
At15955_RS11905	COG0473	3-isopropylmalate dehydrogenase activity
At15955_RS11910	COG1858	cytochrome C peroxidase
At15955_RS11915	COG1797	cobyrinic acid a,c-diamide synthase activity
At15955_RS11920	COG1648	precorrin-2 dehydrogenase activity
At15955_RS11920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
At15955_RS11925	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
At15955_RS11990	COG1492	cobalamin metabolic process
At15955_RS11995	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
At15955_RS12005	COG4948	Mandelate Racemase Muconate Lactonizing
At15955_RS12010	COG3254	rhamnose metabolic process
At15955_RS12015	COG0246	Mannitol dehydrogenase
At15955_RS12020	COG1063	alcohol dehydrogenase
At15955_RS12040	COG4214	carbohydrate transport
At15955_RS12045	COG1129	ABC transporter
At15955_RS12050	COG2186	Transcriptional regulator
At15955_RS12055	COG2721	sulfolactate sulfo-lyase activity
At15955_RS12060	COG0138	bifunctional purine biosynthesis protein purh
At15955_RS12070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
At15955_RS12070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
At15955_RS12075	COG0501	Belongs to the peptidase M48B family
At15955_RS12095	COG0357	Ribosomal RNA small subunit methyltransferase G
At15955_RS12100	COG0445	tRNA wobble uridine modification
At15955_RS12105	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
At15955_RS12110	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
At15955_RS12115	COG1981	membrane
At15955_RS12120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
At15955_RS12125	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
At15955_RS12130	COG0424	maF-like protein
At15955_RS12135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
At15955_RS12140	COG0237	dephospho-CoA kinase activity
At15955_RS12150	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
At15955_RS12165	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
At15955_RS12190	COG0179	Fumarylacetoacetate (FAA) hydrolase
At15955_RS12205	COG0135	phosphoribosylanthranilate isomerase activity
At15955_RS12210	COG0133	tryptophan synthase activity
At15955_RS12215	COG0159	tryptophan synthase activity
At15955_RS12220	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
At15955_RS12225	COG0285	dihydrofolate synthase activity
At15955_RS12235	COG1074	ATP-dependent DNA helicase activity
At15955_RS12245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
At15955_RS12250	COG0802	atpase or kinase
At15955_RS12255	COG2205	protein histidine kinase activity
At15955_RS12265	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
At15955_RS12270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
At15955_RS12275	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
At15955_RS12275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
At15955_RS12280	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
At15955_RS12285	COG0642	Histidine kinase
At15955_RS12290	COG0745	RESPONSE REGULATOR receiver
At15955_RS12295	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
At15955_RS12305	COG1652	LysM domain
At15955_RS12310	COG1072	(Pantothenic acid kinase))
At15955_RS12315	COG0140	phosphoribosyl-ATP diphosphatase activity
At15955_RS12320	COG0107	imidazoleglycerol-phosphate synthase activity
At15955_RS12325	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
At15955_RS12330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
At15955_RS12340	COG0131	Imidazoleglycerol-phosphate dehydratase
At15955_RS12345	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
At15955_RS12350	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
At15955_RS12360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
At15955_RS12375	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
At15955_RS12385	COG1643	Atp-dependent helicase
At15955_RS12430	COG0514	ATP-dependent DNA helicase (RecQ)
At15955_RS12455	COG1072	(Pantothenic acid kinase))
At15955_RS12465	COG1780	Probably involved in ribonucleotide reductase function
At15955_RS12485	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
At15955_RS12510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At15955_RS12525	COG1185	polyribonucleotide nucleotidyltransferase activity
At15955_RS12530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
At15955_RS12535	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
At15955_RS12540	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
At15955_RS12545	COG3064	Membrane
At15955_RS12545	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
At15955_RS12560	COG0779	Required for maturation of 30S ribosomal subunits
At15955_RS12565	COG2814	Major facilitator Superfamily
At15955_RS12575	COG2951	lytic endotransglycosylase activity
At15955_RS12580	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
At15955_RS12590	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
At15955_RS12595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
At15955_RS12610	COG2816	NAD+ diphosphatase activity
At15955_RS12615	COG0077	Prephenate dehydratase
At15955_RS12615	COG1605	Chorismate mutase
At15955_RS12620	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
At15955_RS12625	COG3474	cytochrome
At15955_RS12635	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
At15955_RS12640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
At15955_RS12650	COG1278	Cold shock
At15955_RS12655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
At15955_RS12665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
At15955_RS12665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
At15955_RS12675	COG0333	Belongs to the bacterial ribosomal protein bL32 family
At15955_RS12710	COG2900	Belongs to the SlyX family
At15955_RS12720	COG0484	heat shock protein binding
At15955_RS12725	COG0443	Heat shock 70 kDa protein
At15955_RS12740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
At15955_RS12745	COG1744	ABC transporter substrate-binding protein PnrA-like
At15955_RS12750	COG3845	ABC transporter
At15955_RS12755	COG1079	Belongs to the binding-protein-dependent transport system permease family
At15955_RS12760	COG1079	Belongs to the binding-protein-dependent transport system permease family
At15955_RS12765	COG0295	cytidine deaminase activity
At15955_RS12775	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
At15955_RS12780	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
At15955_RS12790	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
At15955_RS12795	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
At15955_RS12800	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
At15955_RS12815	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
At15955_RS12820	COG1845	cytochrome c oxidase, subunit III
At15955_RS12825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
At15955_RS12830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
At15955_RS12835	COG0477	Major facilitator Superfamily
At15955_RS12840	COG0067	glutamate synthase
At15955_RS12840	COG0070	glutamate synthase
At15955_RS12840	COG0069	glutamate synthase activity
At15955_RS12845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
At15955_RS12860	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
At15955_RS12870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
At15955_RS12905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At15955_RS12925	COG0848	biopolymer transport protein
At15955_RS12935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
At15955_RS12950	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
At15955_RS12955	COG3454	Phosphonate metabolism
At15955_RS12960	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
At15955_RS12965	COG3639	organic phosphonate transmembrane transporter activity
At15955_RS12970	COG3639	organic phosphonate transmembrane transporter activity
At15955_RS12980	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
At15955_RS12990	COG4778	phosphonate C-P lyase system protein PhnL
At15955_RS12995	COG4107	phosphonate C-P lyase system protein PhnK
At15955_RS13000	COG3627	carbon phosphorus lyase activity
At15955_RS13005	COG3626	phosphonate metabolism
At15955_RS13010	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
At15955_RS13015	COG3624	Phosphonate C-P lyase system protein PhnG
At15955_RS13020	COG2188	Transcriptional regulator
At15955_RS13025	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
At15955_RS13030	COG0837	glucose binding
At15955_RS13035	COG1803	Methylglyoxal synthase
At15955_RS13040	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
At15955_RS13045	COG4166	transmembrane transport
At15955_RS13050	COG4174	ABC transporter (Permease)
At15955_RS13055	COG4239	(ABC) transporter, permease
At15955_RS13060	COG4172	Belongs to the ABC transporter superfamily
At15955_RS13065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS13070	COG0174	glutamine synthetase
At15955_RS13075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS13080	COG3265	gluconokinase activity
At15955_RS13085	COG1174	glycine betaine transport
At15955_RS13090	COG1125	glycine betaine transport
At15955_RS13095	COG1174	glycine betaine transport
At15955_RS13100	COG1732	Glycine betaine
At15955_RS13110	COG1959	2 iron, 2 sulfur cluster binding
At15955_RS13115	COG1840	ABC-type Fe3 transport system, periplasmic component
At15955_RS13135	COG0697	spore germination
At15955_RS13150	COG0791	NLP P60 protein
At15955_RS13160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
At15955_RS13165	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
At15955_RS13200	COG4964	Belongs to the GSP D family
At15955_RS13250	COG3422	double-strand break repair
At15955_RS13255	COG3757	hydrolase, family 25
At15955_RS13260	COG0697	spore germination
At15955_RS13265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
At15955_RS13295	COG0481	GTPase activity
At15955_RS13300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
At15955_RS13330	COG2169	Transcriptional regulator
At15955_RS13330	COG1917	Cupin 2, conserved barrel domain protein
At15955_RS13335	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
At15955_RS13360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
At15955_RS13365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
At15955_RS13370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
At15955_RS13380	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
At15955_RS13385	COG0072	phenylalanine-tRNA ligase activity
At15955_RS13385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
At15955_RS13390	COG0667	Aldo Keto reductase
At15955_RS13410	COG4977	sequence-specific DNA binding
At15955_RS13435	COG1570	exodeoxyribonuclease VII activity
At15955_RS13440	COG4948	Mandelate Racemase Muconate Lactonizing
At15955_RS13450	COG1846	Transcriptional regulator
At15955_RS13455	COG0697	spore germination
At15955_RS13460	COG2309	aminopeptidase activity
At15955_RS13470	COG1393	Belongs to the ArsC family
At15955_RS13485	COG0519	Catalyzes the synthesis of GMP from XMP
At15955_RS13485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
At15955_RS13500	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
At15955_RS13530	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
At15955_RS13540	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
At15955_RS13550	COG1968	undecaprenyl-diphosphatase activity
At15955_RS13575	COG0284	orotidine-5'-phosphate decarboxylase activity
At15955_RS13585	COG3963	phosphatidate phosphatase activity
At15955_RS13595	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
At15955_RS13600	COG0792	nuclease activity
At15955_RS13615	COG1175	transmembrane transport
At15955_RS13620	COG0395	ABC-type sugar transport system, permease component
At15955_RS13625	COG3842	ATPase activity
At15955_RS13635	COG0189	ligase activity
At15955_RS13645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
At15955_RS13650	COG1280	lysine exporter protein (LysE YggA)
At15955_RS13655	COG0756	dUTP diphosphatase activity
At15955_RS13660	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
At15955_RS13665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
At15955_RS13680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
At15955_RS13685	COG2226	methyltransferase
At15955_RS13690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
At15955_RS13695	COG1024	Enoyl-CoA hydratase
At15955_RS13700	COG0268	Binds directly to 16S ribosomal RNA
At15955_RS13795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
At15955_RS13825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
At15955_RS13845	COG4372	Transposase
At15955_RS13850	COG3436	PFAM IS66 Orf2 family protein
At15955_RS13955	COG0596	Alpha beta hydrolase
At15955_RS13990	COG1764	response to oxidative stress
At15955_RS13995	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
At15955_RS14000	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
At15955_RS14000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
At15955_RS14005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
At15955_RS14015	COG1414	Transcriptional regulator
At15955_RS14030	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS14050	COG1522	sequence-specific DNA binding
At15955_RS14085	COG0747	negative chemotaxis
At15955_RS14090	COG0601	transmembrane transport
At15955_RS14095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS14100	COG4172	Belongs to the ABC transporter superfamily
At15955_RS14110	COG1027	Aspartate ammonia-lyase
At15955_RS14115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS14120	COG1126	abc transporter atp-binding protein
At15955_RS14130	COG0765	amino acid transport
At15955_RS14135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS14150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS14155	COG1802	Transcriptional regulator
At15955_RS14160	COG3842	ATPase activity
At15955_RS14165	COG4209	transmembrane transport
At15955_RS14170	COG0395	ABC-type sugar transport system, permease component
At15955_RS14175	COG1653	transport
At15955_RS14185	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS14195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
At15955_RS14205	COG4948	Mandelate Racemase Muconate Lactonizing
At15955_RS14215	COG0071	Belongs to the small heat shock protein (HSP20) family
At15955_RS14230	COG0438	transferase activity, transferring glycosyl groups
At15955_RS14250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
At15955_RS14285	COG2197	response regulator
At15955_RS14290	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
At15955_RS14295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
At15955_RS14300	COG4310	Domain of unknown function (DUF2172)
At15955_RS14305	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
At15955_RS14315	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
At15955_RS14320	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
At15955_RS14325	COG2197	response regulator
At15955_RS14350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At15955_RS14390	COG4178	(ABC) transporter
At15955_RS14410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
At15955_RS14420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
At15955_RS14430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
At15955_RS14445	COG1177	transmembrane transport
At15955_RS14450	COG1176	ABC-type spermidine putrescine transport system, permease component I
At15955_RS14455	COG3842	ATPase activity
At15955_RS14490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS14495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS14500	COG0601	transmembrane transport
At15955_RS14505	COG0747	negative chemotaxis
At15955_RS14535	COG1522	sequence-specific DNA binding
At15955_RS14555	COG0477	Major facilitator Superfamily
At15955_RS14560	COG0583	DNA-binding transcription factor activity
At15955_RS14580	COG0583	DNA-binding transcription factor activity
At15955_RS14590	COG0747	negative chemotaxis
At15955_RS14595	COG0601	transmembrane transport
At15955_RS14600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS14620	COG1278	Cold shock
At15955_RS14640	COG5002	protein histidine kinase activity
At15955_RS14640	COG0784	Response regulator, receiver
At15955_RS14640	COG2198	Histidine kinase
At15955_RS14650	COG0405	Gamma-glutamyltransferase
At15955_RS14655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS14660	COG0601	transmembrane transport
At15955_RS14665	COG0747	negative chemotaxis
At15955_RS14670	COG2186	Transcriptional regulator
At15955_RS14710	COG1595	DNA-templated transcription, initiation
At15955_RS14720	COG0395	ABC-type sugar transport system, permease component
At15955_RS14725	COG1176	ABC-type spermidine putrescine transport system, permease component I
At15955_RS14735	COG3842	ATPase activity
At15955_RS14745	COG0765	amino acid transport
At15955_RS14750	COG0765	amino acid transport
At15955_RS14755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS14760	COG2186	Transcriptional regulator
At15955_RS14775	COG1063	alcohol dehydrogenase
At15955_RS14780	COG3284	Transcriptional regulator
At15955_RS14810	COG1653	transport
At15955_RS14815	COG1175	transmembrane transport
At15955_RS14820	COG0395	ABC-type sugar transport system, permease component
At15955_RS14825	COG3842	ATPase activity
At15955_RS14835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At15955_RS14840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At15955_RS14845	COG1116	anion transmembrane transporter activity
At15955_RS14850	COG0395	ABC-type sugar transport system, permease component
At15955_RS14855	COG1175	transmembrane transport
At15955_RS14885	COG1609	Transcriptional regulator
At15955_RS14900	COG1082	Xylose isomerase domain protein TIM barrel
At15955_RS14905	COG3842	ATPase activity
At15955_RS14910	COG0395	ABC-type sugar transport system, permease component
At15955_RS14915	COG1175	transmembrane transport
At15955_RS14920	COG1653	transport
At15955_RS14925	COG1309	transcriptional regulator
At15955_RS14930	COG0673	inositol 2-dehydrogenase activity
At15955_RS14945	COG0673	inositol 2-dehydrogenase activity
At15955_RS14955	COG1278	Cold shock
At15955_RS14965	COG0828	Belongs to the bacterial ribosomal protein bS21 family
At15955_RS14995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
At15955_RS15000	COG1136	(ABC) transporter
At15955_RS15000	COG0577	efflux transmembrane transporter activity
At15955_RS15005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At15955_RS15030	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
At15955_RS15045	COG3842	ATPase activity
At15955_RS15050	COG0395	ABC-type sugar transport system, permease component
At15955_RS15055	COG1175	transmembrane transport
At15955_RS15075	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
At15955_RS15080	COG3618	amidohydrolase
At15955_RS15085	COG4948	Mandelate Racemase Muconate Lactonizing
At15955_RS15090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At15955_RS15095	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS15100	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
At15955_RS15105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At15955_RS15110	COG2186	Transcriptional regulator
At15955_RS15125	COG0667	Aldo Keto reductase
At15955_RS15160	COG2223	nitrite transmembrane transporter activity
At15955_RS15165	COG0583	DNA-binding transcription factor activity
At15955_RS15170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
At15955_RS15180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
At15955_RS15185	COG2084	Dehydrogenase
At15955_RS15200	COG1609	Transcriptional regulator
At15955_RS15205	COG1063	alcohol dehydrogenase
At15955_RS15210	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS15225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At15955_RS15230	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
At15955_RS15235	COG1175	transmembrane transport
At15955_RS15240	COG0395	ABC-type sugar transport system, permease component
At15955_RS15255	COG0395	ABC-type sugar transport system, permease component
At15955_RS15265	COG2182	Extracellular solute-binding protein
At15955_RS15270	COG0626	cystathionine gamma-synthase activity
At15955_RS15280	COG0803	Belongs to the bacterial solute-binding protein 9 family
At15955_RS15290	COG1121	(ABC) transporter
At15955_RS15295	COG0523	cobalamin synthesis protein
At15955_RS15310	COG0523	cobalamin synthesis protein
At15955_RS15315	COG1653	transport
At15955_RS15320	COG1175	transmembrane transport
At15955_RS15325	COG0395	ABC-type sugar transport system, permease component
At15955_RS15330	COG3842	ATPase activity
At15955_RS15340	COG3047	cAMP biosynthetic process
At15955_RS15365	COG0583	DNA-binding transcription factor activity
At15955_RS15370	COG1879	ABC-type sugar transport system periplasmic component
At15955_RS15375	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS15380	COG1129	ABC transporter
At15955_RS15385	COG5001	Diguanylate cyclase
At15955_RS15385	COG3447	MASE1 domain protein
At15955_RS15385	COG5002	protein histidine kinase activity
At15955_RS15390	COG3257	ureidoglycine aminohydrolase activity
At15955_RS15400	COG5001	Diguanylate cyclase
At15955_RS15405	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
At15955_RS15415	COG0747	negative chemotaxis
At15955_RS15420	COG0601	transmembrane transport
At15955_RS15425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS15435	COG4608	Belongs to the ABC transporter superfamily
At15955_RS15440	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
At15955_RS15450	COG0129	dihydroxy-acid dehydratase activity
At15955_RS15455	COG1879	ABC-type sugar transport system periplasmic component
At15955_RS15460	COG1129	ABC transporter
At15955_RS15465	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS15470	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS15475	COG2186	Transcriptional regulator
At15955_RS15490	COG0587	DNA-directed DNA polymerase activity
At15955_RS15525	COG0673	inositol 2-dehydrogenase activity
At15955_RS15535	COG3842	ATPase activity
At15955_RS15540	COG0395	ABC-type sugar transport system, permease component
At15955_RS15545	COG1175	transmembrane transport
At15955_RS15550	COG1653	transport
At15955_RS15560	COG0673	inositol 2-dehydrogenase activity
At15955_RS15575	COG5001	Diguanylate cyclase
At15955_RS15590	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
At15955_RS15595	COG2894	cell division
At15955_RS15600	COG0850	regulation of cytokinetic process
At15955_RS15605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
At15955_RS15610	COG2186	Transcriptional regulator
At15955_RS15615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
At15955_RS15625	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
At15955_RS15630	COG1063	alcohol dehydrogenase
At15955_RS15635	COG1312	Catalyzes the dehydration of D-mannonate
At15955_RS15650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
At15955_RS15655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
At15955_RS15655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
At15955_RS15660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS15680	COG0625	glutathione transferase activity
At15955_RS15685	COG4172	Belongs to the ABC transporter superfamily
At15955_RS15690	COG1921	L-seryl-tRNASec selenium transferase activity
At15955_RS15705	COG3964	amidohydrolase
At15955_RS15715	COG0601	transmembrane transport
At15955_RS15720	COG0747	negative chemotaxis
At15955_RS15730	COG0438	transferase activity, transferring glycosyl groups
At15955_RS15775	COG4989	oxidoreductase activity
At15955_RS15785	COG2188	Transcriptional regulator
At15955_RS15790	COG3842	ATPase activity
At15955_RS15795	COG1653	transport
At15955_RS15800	COG1175	transmembrane transport
At15955_RS15805	COG0395	ABC-type sugar transport system, permease component
At15955_RS15810	COG1501	Belongs to the glycosyl hydrolase 31 family
At15955_RS15820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At15955_RS15825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At15955_RS15830	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
At15955_RS15835	COG0352	thiamine-phosphate diphosphorylase activity
At15955_RS15840	COG0351	phosphomethylpyrimidine kinase
At15955_RS15845	COG1522	sequence-specific DNA binding
At15955_RS15850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
At15955_RS15855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS15870	COG2204	response regulator
At15955_RS15875	COG4191	Histidine kinase
At15955_RS15880	COG1301	dicarboxylic acid transport
At15955_RS15890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
At15955_RS15895	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS15905	COG1473	amidohydrolase
At15955_RS15925	COG1215	transferase activity, transferring glycosyl groups
At15955_RS15935	COG2942	2-epimerase
At15955_RS15960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At15955_RS16000	COG3307	-O-antigen
At15955_RS16005	COG1596	polysaccharide export
At15955_RS16010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
At15955_RS16025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
At15955_RS16030	COG0840	transmembrane signaling receptor activity
At15955_RS16035	COG1376	ErfK ybiS ycfS ynhG family protein
At15955_RS16045	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS16055	COG2094	Belongs to the DNA glycosylase MPG family
At15955_RS16070	COG1609	Transcriptional regulator
At15955_RS16075	COG1653	transport
At15955_RS16090	COG3842	ATPase activity
At15955_RS16100	COG0673	inositol 2-dehydrogenase activity
At15955_RS16105	COG0602	queuosine metabolic process
At15955_RS16110	COG0720	synthase
At15955_RS16115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
At15955_RS16120	COG0673	inositol 2-dehydrogenase activity
At15955_RS16135	COG0395	ABC-type sugar transport system, permease component
At15955_RS16140	COG1175	transmembrane transport
At15955_RS16170	COG0583	DNA-binding transcription factor activity
At15955_RS16175	COG0281	malic enzyme
At15955_RS16175	COG0280	phosphate acetyltransferase
At15955_RS16190	COG0765	amino acid transport
At15955_RS16195	COG1126	abc transporter atp-binding protein
At15955_RS16200	COG2079	MmgE PrpD family protein
At15955_RS16205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS16215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS16235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
At15955_RS16245	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
At15955_RS16250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
At15955_RS16255	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS16260	COG1129	ABC transporter
At15955_RS16275	COG1473	amidohydrolase
At15955_RS16280	COG0747	negative chemotaxis
At15955_RS16295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS16300	COG0601	transmembrane transport
At15955_RS16305	COG0583	DNA-binding transcription factor activity
At15955_RS16310	COG1446	asparaginase
At15955_RS16325	COG0747	negative chemotaxis
At15955_RS16345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS16350	COG0601	transmembrane transport
At15955_RS16355	COG2197	response regulator
At15955_RS16360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At15955_RS16365	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
At15955_RS16385	COG1595	DNA-templated transcription, initiation
At15955_RS16390	COG1120	ATPase activity
At15955_RS16395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS16410	COG2226	methyltransferase
At15955_RS16415	COG3794	PFAM blue (type 1) copper domain protein
At15955_RS16420	COG1120	ATPase activity
At15955_RS16425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS16445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
At15955_RS16460	COG1012	belongs to the aldehyde dehydrogenase family
At15955_RS16465	COG0473	3-isopropylmalate dehydrogenase activity
At15955_RS16470	COG1012	belongs to the aldehyde dehydrogenase family
At15955_RS16475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS16505	COG0601	transmembrane transport
At15955_RS16510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS16515	COG4172	Belongs to the ABC transporter superfamily
At15955_RS16520	COG1522	sequence-specific DNA binding
At15955_RS16535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS16540	COG1126	abc transporter atp-binding protein
At15955_RS16550	COG1473	amidohydrolase
At15955_RS16555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS16560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS16565	COG1959	2 iron, 2 sulfur cluster binding
At15955_RS16575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
At15955_RS16580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS16600	COG1960	acyl-CoA dehydrogenase activity
At15955_RS16610	COG0747	negative chemotaxis
At15955_RS16625	COG0444	Belongs to the ABC transporter superfamily
At15955_RS16635	COG0667	Aldo Keto reductase
At15955_RS16645	COG0583	DNA-binding transcription factor activity
At15955_RS16650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS16665	COG0747	negative chemotaxis
At15955_RS16670	COG1473	amidohydrolase
At15955_RS16675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS16690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS16695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS16715	COG4608	Belongs to the ABC transporter superfamily
At15955_RS16720	COG0444	Belongs to the ABC transporter superfamily
At15955_RS16730	COG0601	transmembrane transport
At15955_RS16740	COG2186	Transcriptional regulator
At15955_RS16755	COG0300	oxidoreductase activity
At15955_RS16765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
At15955_RS16765	COG3453	Protein conserved in bacteria
At15955_RS16770	COG0640	Transcriptional regulator
At15955_RS16780	COG2391	methyltransferase activity
At15955_RS16785	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
At15955_RS16800	COG0022	dehydrogenase e1 component
At15955_RS16810	COG1960	acyl-CoA dehydrogenase activity
At15955_RS16815	COG0183	Belongs to the thiolase family
At15955_RS16825	COG1960	acyl-CoA dehydrogenase activity
At15955_RS16830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
At15955_RS16845	COG1024	Enoyl-CoA hydratase
At15955_RS16850	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
At15955_RS16855	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
At15955_RS16860	COG4952	isomerase
At15955_RS16865	COG3347	Dehydrogenase
At15955_RS16865	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS16870	COG1349	DNA-binding transcription factor activity
At15955_RS16880	COG1129	ABC transporter
At15955_RS16885	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS16890	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS16895	COG3254	rhamnose metabolic process
At15955_RS16910	COG2264	protein methyltransferase activity
At15955_RS16915	COG5001	Diguanylate cyclase
At15955_RS16930	COG4335	DNA alkylation repair
At15955_RS16935	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
At15955_RS16940	COG4208	sulfate ABC transporter
At15955_RS16950	COG4150	thiosulfate binding
At15955_RS16955	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
At15955_RS16970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
At15955_RS16980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
At15955_RS16990	COG1040	competence protein
At15955_RS16995	COG2226	methyltransferase
At15955_RS17010	COG0494	nUDIX hydrolase
At15955_RS17020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
At15955_RS17025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
At15955_RS17030	COG0653	protein targeting
At15955_RS17100	COG2244	polysaccharide biosynthetic process
At15955_RS17115	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
At15955_RS17145	COG0438	transferase activity, transferring glycosyl groups
At15955_RS17150	COG0438	transferase activity, transferring glycosyl groups
At15955_RS17165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
At15955_RS17170	COG2273	Hydrolase Family 16
At15955_RS17170	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
At15955_RS17185	COG3842	ATPase activity
At15955_RS17190	COG3833	ABC-type maltose transport systems, permease component
At15955_RS17245	COG1396	sequence-specific DNA binding
At15955_RS17255	COG1129	ABC transporter
At15955_RS17260	COG4214	carbohydrate transport
At15955_RS17265	COG4213	ABC transporter substrate-binding protein
At15955_RS17280	COG0346	lactoylglutathione lyase activity
At15955_RS17285	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
At15955_RS17285	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
At15955_RS17290	COG4770	biotin carboxylase activity
At15955_RS17295	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
At15955_RS17305	COG0625	glutathione transferase activity
At15955_RS17310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
At15955_RS17315	COG3800	Transcriptional regulator
At15955_RS17315	COG1396	sequence-specific DNA binding
At15955_RS17325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
At15955_RS17335	COG0300	oxidoreductase activity
At15955_RS17345	COG2096	Adenosyltransferase
At15955_RS17355	COG2086	electron transfer activity
At15955_RS17365	COG1250	3-hydroxyacyl-CoA dehydrogenase
At15955_RS17370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
At15955_RS17375	COG0165	Argininosuccinate lyase
At15955_RS17385	COG0019	diaminopimelate decarboxylase activity
At15955_RS17410	COG2884	Cell division ATP-binding protein ftsE
At15955_RS17430	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
At15955_RS17445	COG0287	Prephenate dehydrogenase
At15955_RS17450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
At15955_RS17455	COG2226	methyltransferase
At15955_RS17460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
At15955_RS17475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
At15955_RS17480	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
At15955_RS17515	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
At15955_RS17520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
At15955_RS17535	COG4974	Belongs to the 'phage' integrase family
At15955_RS17540	COG0825	malonyl-CoA metabolic process
At15955_RS17545	COG3034	peptidoglycan biosynthetic process
At15955_RS17550	COG0425	Belongs to the sulfur carrier protein TusA family
At15955_RS17555	COG0523	cobalamin synthesis protein
At15955_RS17560	COG1686	Belongs to the peptidase S11 family
At15955_RS17570	COG1473	amidohydrolase
At15955_RS17580	COG4953	penicillin-binding protein 1C
At15955_RS17585	COG2373	Large extracellular alpha-helical protein
At15955_RS17590	COG2835	tetraacyldisaccharide 4'-kinase activity
At15955_RS17600	COG3118	belongs to the thioredoxin family
At15955_RS17620	COG0482	sulfurtransferase activity
At15955_RS17635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
At15955_RS17650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
At15955_RS17655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
At15955_RS17660	COG0037	tRNA processing
At15955_RS17670	COG2885	chlorophyll binding
At15955_RS17675	COG0823	Involved in the tonB-independent uptake of proteins
At15955_RS17695	COG0824	Thioesterase
At15955_RS17705	COG0494	nUDIX hydrolase
At15955_RS17720	COG2255	four-way junction helicase activity
At15955_RS17725	COG0632	four-way junction helicase activity
At15955_RS17730	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
At15955_RS17735	COG0840	transmembrane signaling receptor activity
At15955_RS17735	COG2972	Histidine kinase
At15955_RS17740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS17745	COG0217	transcriptional regulatory protein
At15955_RS17760	COG1692	metallophosphoesterase
At15955_RS17770	COG1253	flavin adenine dinucleotide binding
At15955_RS17820	COG0126	phosphoglycerate kinase activity
At15955_RS17825	COG3588	fructose-bisphosphate aldolase
At15955_RS17845	COG0254	rRNA binding
At15955_RS17850	COG1132	(ABC) transporter
At15955_RS17870	COG0483	inositol monophosphate 1-phosphatase activity
At15955_RS17900	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
At15955_RS17905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
At15955_RS17910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
At15955_RS17915	COG0457	Tetratricopeptide repeat
At15955_RS17920	COG3750	Belongs to the UPF0335 family
At15955_RS17940	COG0469	pyruvate kinase activity
At15955_RS17945	COG3108	Peptidase M15
At15955_RS17950	COG2204	response regulator
At15955_RS17955	COG1164	Oligoendopeptidase f
At15955_RS17960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
At15955_RS17970	COG5310	Homospermidine synthase
At15955_RS17980	COG0737	Belongs to the 5'-nucleotidase family
At15955_RS17985	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
At15955_RS17990	COG0330	HflC and HflK could
At15955_RS18020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
At15955_RS18025	COG2951	lytic endotransglycosylase activity
At15955_RS18040	COG2205	protein histidine kinase activity
At15955_RS18050	COG0067	glutamate synthase
At15955_RS18050	COG0070	glutamate synthase
At15955_RS18050	COG0069	glutamate synthase activity
At15955_RS18065	COG2205	protein histidine kinase activity
At15955_RS18070	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
At15955_RS18075	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
At15955_RS18080	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
At15955_RS18090	COG0252	asparaginase activity
At15955_RS18100	COG1027	Aspartate ammonia-lyase
At15955_RS18110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
At15955_RS18130	COG3239	Fatty acid desaturase
At15955_RS18150	COG0583	DNA-binding transcription factor activity
At15955_RS18170	COG3842	ATPase activity
At15955_RS18175	COG1177	transmembrane transport
At15955_RS18195	COG1012	belongs to the aldehyde dehydrogenase family
At15955_RS18200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS18210	COG2267	carboxylic ester hydrolase activity
At15955_RS18225	COG1126	abc transporter atp-binding protein
At15955_RS18230	COG0765	amino acid transport
At15955_RS18250	COG0174	glutamine synthetase
At15955_RS18255	COG0069	glutamate synthase activity
At15955_RS18260	COG2218	PFAM glutamate synthase alpha subunit domain protein
At15955_RS18265	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
At15955_RS18340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At15955_RS18350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS18355	COG0601	transmembrane transport
At15955_RS18360	COG0747	negative chemotaxis
At15955_RS18370	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
At15955_RS18375	COG1454	alcohol dehydrogenase
At15955_RS18425	COG2307	Protein conserved in bacteria
At15955_RS18425	COG2308	Evidence 4 Homologs of previously reported genes of
At15955_RS18440	COG0488	(ABC) transporter
At15955_RS18445	COG1304	FMN binding
At15955_RS18450	COG1846	Transcriptional regulator
At15955_RS18455	COG0840	transmembrane signaling receptor activity
At15955_RS18460	COG1070	Carbohydrate kinase
At15955_RS18465	COG1830	Aldolase
At15955_RS18470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
At15955_RS18475	COG0667	Aldo Keto reductase
At15955_RS18485	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS18490	COG1129	ABC transporter
At15955_RS18495	COG1879	ABC-type sugar transport system periplasmic component
At15955_RS18530	COG0071	Belongs to the small heat shock protein (HSP20) family
At15955_RS18545	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
At15955_RS18560	COG0395	ABC-type sugar transport system, permease component
At15955_RS18570	COG3842	ATPase activity
At15955_RS18575	COG3842	ATPase activity
At15955_RS18590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
At15955_RS18590	COG1648	precorrin-2 dehydrogenase activity
At15955_RS18595	COG0243	molybdopterin cofactor binding
At15955_RS18610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
At15955_RS18615	COG1116	anion transmembrane transporter activity
At15955_RS18620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At15955_RS18625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At15955_RS18635	COG3707	response regulator
At15955_RS18640	COG1802	Transcriptional regulator
At15955_RS18645	COG1914	H( )-stimulated, divalent metal cation uptake system
At15955_RS18650	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
At15955_RS18655	COG4336	lyase activity
At15955_RS18660	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
At15955_RS18665	COG4770	biotin carboxylase activity
At15955_RS18670	COG0366	Alpha amylase catalytic
At15955_RS18680	COG4771	TonB-dependent receptor
At15955_RS18685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
At15955_RS18705	COG1414	Transcriptional regulator
At15955_RS18710	COG1475	DNA binding
At15955_RS18715	COG1192	Involved in chromosome partitioning
At15955_RS18745	COG0596	Alpha beta hydrolase
At15955_RS18750	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
At15955_RS18760	COG2986	histidine ammonia-lyase
At15955_RS18765	COG1228	amidohydrolase
At15955_RS18770	COG0402	S-adenosylhomocysteine deaminase activity
At15955_RS18820	COG0511	ligase activity, forming carbon-carbon bonds
At15955_RS18825	COG0439	Biotin carboxylase
At15955_RS18840	COG1984	allophanate hydrolase subunit 2
At15955_RS18845	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
At15955_RS18850	COG0436	Aminotransferase
At15955_RS18860	COG4221	oxidoreductase activity
At15955_RS18865	COG0765	amino acid transport
At15955_RS18870	COG0765	amino acid transport
At15955_RS18875	COG1126	abc transporter atp-binding protein
At15955_RS18880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS18885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
At15955_RS18890	COG0010	Belongs to the arginase family
At15955_RS18895	COG1126	abc transporter atp-binding protein
At15955_RS18905	COG0765	amino acid transport
At15955_RS18920	COG0640	Transcriptional regulator
At15955_RS18930	COG0431	NADPH-dependent FMN reductase
At15955_RS18940	COG0798	PFAM Bile acid sodium symporter
At15955_RS18950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
At15955_RS18955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At15955_RS18965	COG3842	ATPase activity
At15955_RS18970	COG0395	ABC-type sugar transport system, permease component
At15955_RS18975	COG1175	transmembrane transport
At15955_RS18985	COG0673	inositol 2-dehydrogenase activity
At15955_RS18990	COG0673	inositol 2-dehydrogenase activity
At15955_RS19035	COG0583	DNA-binding transcription factor activity
At15955_RS19040	COG0477	Major facilitator Superfamily
At15955_RS19050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS19060	COG4172	Belongs to the ABC transporter superfamily
At15955_RS19065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS19070	COG0601	transmembrane transport
At15955_RS19085	COG0277	FAD linked oxidase domain protein
At15955_RS19105	COG2205	protein histidine kinase activity
At15955_RS19110	COG0745	RESPONSE REGULATOR receiver
At15955_RS19115	COG0671	phosphoesterase, PA-phosphatase related
At15955_RS19170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
At15955_RS19180	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
At15955_RS19185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
At15955_RS19190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
At15955_RS19205	COG0010	Belongs to the arginase family
At15955_RS19215	COG0697	spore germination
At15955_RS19220	COG0673	inositol 2-dehydrogenase activity
At15955_RS19245	COG0477	Major facilitator Superfamily
At15955_RS19250	COG0642	Histidine kinase
At15955_RS19260	COG2194	sulfuric ester hydrolase activity
At15955_RS19270	COG0583	DNA-binding transcription factor activity
At15955_RS19275	COG4774	siderophore transport
At15955_RS19290	COG1120	ATPase activity
At15955_RS19305	COG2137	regulation of response to DNA damage stimulus
At15955_RS19310	COG3386	PFAM SMP-30 Gluconolaconase
At15955_RS19320	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS19325	COG1129	ABC transporter
At15955_RS19330	COG1879	ABC-type sugar transport system periplasmic component
At15955_RS19340	COG4585	Histidine kinase
At15955_RS19345	COG2197	response regulator
At15955_RS19355	COG2133	pyrroloquinoline quinone binding
At15955_RS19365	COG0500	methyltransferase
At15955_RS19370	COG0564	pseudouridine synthase activity
At15955_RS19385	COG0517	IMP dehydrogenase activity
At15955_RS19385	COG4175	Glycine betaine
At15955_RS19390	COG4176	ABC-type proline glycine betaine transport system permease component
At15955_RS19400	COG0784	Response regulator, receiver
At15955_RS19400	COG4191	Histidine kinase
At15955_RS19405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
At15955_RS19410	COG3206	protein involved in exopolysaccharide biosynthesis
At15955_RS19410	COG0489	protein tyrosine kinase activity
At15955_RS19415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
At15955_RS19420	COG1215	transferase activity, transferring glycosyl groups
At15955_RS19425	COG1215	transferase activity, transferring glycosyl groups
At15955_RS19430	COG1215	transferase activity, transferring glycosyl groups
At15955_RS19435	COG0438	transferase activity, transferring glycosyl groups
At15955_RS19440	COG2273	Hydrolase Family 16
At15955_RS19445	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
At15955_RS19450	COG2244	polysaccharide biosynthetic process
At15955_RS19455	COG0463	Glycosyl transferase, family 2
At15955_RS19460	COG2327	Polysaccharide pyruvyl transferase
At15955_RS19465	COG1215	transferase activity, transferring glycosyl groups
At15955_RS19485	COG0828	Belongs to the bacterial ribosomal protein bS21 family
At15955_RS19495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS19510	COG0446	pyridine nucleotide-disulphide oxidoreductase
At15955_RS19510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
At15955_RS19535	COG1523	belongs to the glycosyl hydrolase 13 family
At15955_RS19540	COG0033	Phosphoglucomutase
At15955_RS19545	COG0297	glycogen (starch) synthase activity
At15955_RS19550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
At15955_RS19555	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
At15955_RS19560	COG0058	SHG alpha-glucan phosphorylase activity
At15955_RS19575	COG1794	racemase activity, acting on amino acids and derivatives
At15955_RS19580	COG1522	sequence-specific DNA binding
At15955_RS19590	COG2084	Dehydrogenase
At15955_RS19595	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS19600	COG1063	alcohol dehydrogenase
At15955_RS19610	COG4988	ABC transporter
At15955_RS19615	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
At15955_RS19625	COG1294	oxidase, subunit
At15955_RS19655	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
At15955_RS19660	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
At15955_RS19690	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
At15955_RS19695	COG0539	negative regulation of cytoplasmic translation
At15955_RS19725	COG4221	oxidoreductase activity
At15955_RS19735	COG0006	proline dipeptidase activity
At15955_RS19740	COG0747	negative chemotaxis
At15955_RS19745	COG0601	transmembrane transport
At15955_RS19750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS19755	COG0444	Belongs to the ABC transporter superfamily
At15955_RS19760	COG4608	Belongs to the ABC transporter superfamily
At15955_RS19775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS19790	COG0411	ABC transporter
At15955_RS19800	COG0559	Belongs to the binding-protein-dependent transport system permease family
At15955_RS19820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
At15955_RS19825	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS19845	COG4993	Dehydrogenase
At15955_RS19850	COG3685	Protein conserved in bacteria
At15955_RS19860	COG0693	protein deglycase activity
At15955_RS19885	COG0189	ligase activity
At15955_RS19890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At15955_RS19895	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
At15955_RS19905	COG0435	Glutathione S-transferase
At15955_RS19910	COG0583	DNA-binding transcription factor activity
At15955_RS19915	COG1012	belongs to the aldehyde dehydrogenase family
At15955_RS19920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At15955_RS19925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At15955_RS19930	COG1116	anion transmembrane transporter activity
At15955_RS19945	COG1522	sequence-specific DNA binding
At15955_RS19960	COG0784	Response regulator, receiver
At15955_RS19980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
At15955_RS20000	COG0019	diaminopimelate decarboxylase activity
At15955_RS20020	COG0527	aspartate kinase activity
At15955_RS20030	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
At15955_RS20035	COG2890	protein-(glutamine-N5) methyltransferase activity
At15955_RS20050	COG0542	response to heat
At15955_RS20055	COG0739	heme binding
At15955_RS20055	COG0741	lytic transglycosylase activity
At15955_RS20055	COG1196	nuclear chromosome segregation
At15955_RS20105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
At15955_RS20110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
At15955_RS20135	COG1309	transcriptional regulator
At15955_RS20140	COG4221	oxidoreductase activity
At15955_RS20145	COG1902	pentaerythritol trinitrate reductase activity
At15955_RS20150	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS20155	COG0604	alcohol dehydrogenase
At15955_RS20165	COG0243	molybdopterin cofactor binding
At15955_RS20170	COG2814	Major facilitator Superfamily
At15955_RS20180	COG0492	ferredoxin-NADP+ reductase activity
At15955_RS20190	COG4566	intracellular signal transduction
At15955_RS20195	COG4566	intracellular signal transduction
At15955_RS20205	COG2140	Oxalate decarboxylase
At15955_RS20210	COG0783	Belongs to the Dps family
At15955_RS20220	COG0583	DNA-binding transcription factor activity
At15955_RS20230	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS20235	COG1846	Transcriptional regulator
At15955_RS20250	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
At15955_RS20255	COG0583	DNA-binding transcription factor activity
At15955_RS20260	COG0346	lactoylglutathione lyase activity
At15955_RS20280	COG1574	metal-dependent hydrolase with the TIM-barrel fold
At15955_RS20295	COG2080	2 iron, 2 sulfur cluster binding
At15955_RS20300	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
At15955_RS20305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
At15955_RS20310	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
At15955_RS20315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
At15955_RS20335	COG1278	Cold shock
At15955_RS20365	COG2986	histidine ammonia-lyase
At15955_RS20385	COG4172	Belongs to the ABC transporter superfamily
At15955_RS20390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS20395	COG0601	transmembrane transport
At15955_RS20400	COG4166	transmembrane transport
At15955_RS20410	COG0840	transmembrane signaling receptor activity
At15955_RS20420	COG5001	Diguanylate cyclase
At15955_RS20420	COG3300	MHYT domain
At15955_RS20440	COG1609	Transcriptional regulator
At15955_RS20455	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS20460	COG1735	metal-dependent hydrolase with the TIM-barrel fold
At15955_RS20485	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
At15955_RS20490	COG1049	propionate catabolic process, 2-methylcitrate cycle
At15955_RS20500	COG0367	asparagine synthase
At15955_RS20510	COG0318	PFAM AMP-dependent synthetase and ligase
At15955_RS20515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
At15955_RS20535	COG0446	pyridine nucleotide-disulphide oxidoreductase
At15955_RS20535	COG0404	The glycine cleavage system catalyzes the degradation of glycine
At15955_RS20540	COG4311	Sarcosine oxidase, delta subunit
At15955_RS20545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS20550	COG4977	sequence-specific DNA binding
At15955_RS20555	COG1129	ABC transporter
At15955_RS20560	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS20565	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS20580	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS20585	COG0246	Mannitol dehydrogenase
At15955_RS20590	COG1312	Catalyzes the dehydration of D-mannonate
At15955_RS20610	COG1309	transcriptional regulator
At15955_RS20615	COG1063	alcohol dehydrogenase
At15955_RS20625	COG1879	ABC-type sugar transport system periplasmic component
At15955_RS20635	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS20655	COG0477	Major facilitator Superfamily
At15955_RS20665	COG0483	inositol monophosphate 1-phosphatase activity
At15955_RS20690	COG1178	ABC-type Fe3 transport system permease component
At15955_RS20695	COG3842	ATPase activity
At15955_RS20725	COG1253	flavin adenine dinucleotide binding
At15955_RS20740	COG3842	ATPase activity
At15955_RS20745	COG0395	ABC-type sugar transport system, permease component
At15955_RS20750	COG1175	transmembrane transport
At15955_RS20755	COG1653	transport
At15955_RS20765	COG0673	inositol 2-dehydrogenase activity
At15955_RS20770	COG1609	Transcriptional regulator
At15955_RS20785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS20795	COG0446	pyridine nucleotide-disulphide oxidoreductase
At15955_RS20795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
At15955_RS20805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
At15955_RS20815	COG0668	transmembrane transport
At15955_RS20845	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS20850	COG3433	isochorismatase activity
At15955_RS20850	COG1535	isochorismatase
At15955_RS20855	COG1021	2,3-dihydroxybenzoate-AMP ligase
At15955_RS20860	COG1169	isochorismate synthase
At15955_RS20870	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
At15955_RS20870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
At15955_RS20875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
At15955_RS20885	COG2375	cellular response to nickel ion
At15955_RS20895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS20900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS20905	COG1120	ATPase activity
At15955_RS20920	COG4774	siderophore transport
At15955_RS20920	COG1629	transport
At15955_RS20925	COG1960	acyl-CoA dehydrogenase activity
At15955_RS20930	COG0583	DNA-binding transcription factor activity
At15955_RS20935	COG1609	Transcriptional regulator
At15955_RS20945	COG1176	ABC-type spermidine putrescine transport system, permease component I
At15955_RS20965	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
At15955_RS20970	COG0583	DNA-binding transcription factor activity
At15955_RS20975	COG2814	Major facilitator Superfamily
At15955_RS20980	COG1473	amidohydrolase
At15955_RS20995	COG0747	negative chemotaxis
At15955_RS21000	COG0601	transmembrane transport
At15955_RS21005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS21010	COG0444	Belongs to the ABC transporter superfamily
At15955_RS21015	COG4608	Belongs to the ABC transporter superfamily
At15955_RS21020	COG0583	DNA-binding transcription factor activity
At15955_RS21025	COG0747	negative chemotaxis
At15955_RS21035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS21045	COG0693	protein deglycase activity
At15955_RS21055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS21060	COG0601	transmembrane transport
At15955_RS21070	COG1473	amidohydrolase
At15955_RS21075	COG4172	Belongs to the ABC transporter superfamily
At15955_RS21080	COG2390	Transcriptional regulator
At15955_RS21090	COG1175	transmembrane transport
At15955_RS21095	COG0395	ABC-type sugar transport system, permease component
At15955_RS21140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
At15955_RS21150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
At15955_RS21155	COG1414	Transcriptional regulator
At15955_RS21160	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS21165	COG5487	UPF0391 membrane protein
At15955_RS21170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
At15955_RS21175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
At15955_RS21180	COG1121	(ABC) transporter
At15955_RS21185	COG0803	Belongs to the bacterial solute-binding protein 9 family
At15955_RS21195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
At15955_RS21200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
At15955_RS21205	COG0471	metal ion transport
At15955_RS21205	COG3273	potassium ion transport
At15955_RS21210	COG1253	flavin adenine dinucleotide binding
At15955_RS21215	COG1309	transcriptional regulator
At15955_RS21230	COG1609	Transcriptional regulator
At15955_RS21235	COG1070	Carbohydrate kinase
At15955_RS21240	COG2115	Belongs to the xylose isomerase family
At15955_RS21260	COG0778	Nitroreductase
At15955_RS21265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
At15955_RS21270	COG2011	ABC-type metal ion transport system permease component
At15955_RS21280	COG3300	MHYT domain
At15955_RS21280	COG5001	Diguanylate cyclase
At15955_RS21285	COG1054	Belongs to the UPF0176 family
At15955_RS21295	COG2954	triphosphatase activity
At15955_RS21300	COG0800	Aldolase
At15955_RS21320	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
At15955_RS21355	COG0523	cobalamin synthesis protein
At15955_RS21365	COG1846	Transcriptional regulator
At15955_RS21370	COG1609	Transcriptional regulator
At15955_RS21375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
At15955_RS21380	COG0673	inositol 2-dehydrogenase activity
At15955_RS21385	COG3718	enzyme involved in inositol metabolism
At15955_RS21395	COG3962	Belongs to the TPP enzyme family
At15955_RS21400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At15955_RS21410	COG3842	ATPase activity
At15955_RS21430	COG0683	leucine binding
At15955_RS21445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS21455	COG0747	negative chemotaxis
At15955_RS21475	COG3185	4-Hydroxyphenylpyruvate dioxygenase
At15955_RS21475	COG1082	Xylose isomerase domain protein TIM barrel
At15955_RS21485	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
At15955_RS21490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
At15955_RS21495	COG1126	abc transporter atp-binding protein
At15955_RS21500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS21505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS21510	COG0765	amino acid transport
At15955_RS21515	COG0765	amino acid transport
At15955_RS21525	COG3485	protocatechuate 3,4-dioxygenase
At15955_RS21530	COG3485	protocatechuate 3,4-dioxygenase
At15955_RS21535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
At15955_RS21545	COG0583	DNA-binding transcription factor activity
At15955_RS21560	COG1414	Transcriptional regulator
At15955_RS21570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
At15955_RS21575	COG0183	Belongs to the thiolase family
At15955_RS21585	COG1609	Transcriptional regulator
At15955_RS21595	COG1082	Xylose isomerase domain protein TIM barrel
At15955_RS21600	COG0673	inositol 2-dehydrogenase activity
At15955_RS21610	COG1609	Transcriptional regulator
At15955_RS21615	COG0395	ABC-type sugar transport system, permease component
At15955_RS21620	COG1175	transmembrane transport
At15955_RS21625	COG3842	ATPase activity
At15955_RS21635	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
At15955_RS21665	COG3842	ATPase activity
At15955_RS21670	COG4149	molybdate abc transporter
At15955_RS21680	COG0584	glycerophosphoryl diester phosphodiesterase
At15955_RS21685	COG0483	inositol monophosphate 1-phosphatase activity
At15955_RS21700	COG3842	ATPase activity
At15955_RS21705	COG1177	transmembrane transport
At15955_RS21720	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
At15955_RS21760	COG3210	domain, Protein
At15955_RS21760	COG3210	domain, Protein
At15955_RS21810	COG0385	Bile acid
At15955_RS21830	COG1132	(ABC) transporter
At15955_RS21840	COG3754	Rhamnan synthesis protein F
At15955_RS21845	COG0438	transferase activity, transferring glycosyl groups
At15955_RS21845	COG1216	Glycosyl transferase, family 2
At15955_RS21860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
At15955_RS21905	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
At15955_RS21910	COG1091	dTDP-4-dehydrorhamnose reductase activity
At15955_RS21915	COG1088	dTDP-glucose 4,6-dehydratase activity
At15955_RS21920	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
At15955_RS21930	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
At15955_RS21935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS21940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS21945	COG1120	ATPase activity
At15955_RS21950	COG4774	siderophore transport
At15955_RS21955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
At15955_RS21970	COG1609	Transcriptional regulator
At15955_RS21975	COG1233	COG1233 Phytoene dehydrogenase and related
At15955_RS21990	COG0395	ABC-type sugar transport system, permease component
At15955_RS21995	COG3842	ATPase activity
At15955_RS22000	COG4608	Belongs to the ABC transporter superfamily
At15955_RS22005	COG0444	Belongs to the ABC transporter superfamily
At15955_RS22010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS22015	COG0601	transmembrane transport
At15955_RS22020	COG2186	Transcriptional regulator
At15955_RS22030	COG0747	negative chemotaxis
At15955_RS22040	COG5001	Diguanylate cyclase
At15955_RS22040	COG3300	MHYT domain
At15955_RS22045	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS22055	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
At15955_RS22065	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
At15955_RS22070	COG0306	phosphate transporter
At15955_RS22075	COG1392	Phosphate transport regulator
At15955_RS22105	COG0745	RESPONSE REGULATOR receiver
At15955_RS22110	COG5002	protein histidine kinase activity
At15955_RS22125	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
At15955_RS22140	COG4774	siderophore transport
At15955_RS22150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS22155	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS22160	COG1120	ATPase activity
At15955_RS22165	COG1733	regulation of RNA biosynthetic process
At15955_RS22190	COG1012	belongs to the aldehyde dehydrogenase family
At15955_RS22205	COG3119	arylsulfatase activity
At15955_RS22210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At15955_RS22215	COG3842	ATPase activity
At15955_RS22220	COG0165	Argininosuccinate lyase
At15955_RS22225	COG0395	ABC-type sugar transport system, permease component
At15955_RS22230	COG1175	transmembrane transport
At15955_RS22235	COG2182	Extracellular solute-binding protein
At15955_RS22240	COG1940	carbohydrate kinase activity
At15955_RS22265	COG1486	melibiose metabolic process
At15955_RS22270	COG0747	negative chemotaxis
At15955_RS22275	COG0601	transmembrane transport
At15955_RS22280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS22285	COG4172	Belongs to the ABC transporter superfamily
At15955_RS22290	COG1486	melibiose metabolic process
At15955_RS22295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At15955_RS22300	COG0842	Transport permease protein
At15955_RS22300	COG1129	ABC transporter
At15955_RS22305	COG0842	Transport permease protein
At15955_RS22320	COG0784	Response regulator, receiver
At15955_RS22325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
At15955_RS22335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At15955_RS22340	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
At15955_RS22355	COG0765	amino acid transport
At15955_RS22365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS22375	COG3938	Belongs to the proline racemase family
At15955_RS22390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS22395	COG0765	amino acid transport
At15955_RS22400	COG0765	amino acid transport
At15955_RS22410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
At15955_RS22425	COG0402	S-adenosylhomocysteine deaminase activity
At15955_RS22435	COG0601	transmembrane transport
At15955_RS22440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS22450	COG0402	S-adenosylhomocysteine deaminase activity
At15955_RS22455	COG0444	Belongs to the ABC transporter superfamily
At15955_RS22460	COG4608	Belongs to the ABC transporter superfamily
At15955_RS22465	COG1802	Transcriptional regulator
At15955_RS22470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
At15955_RS22495	COG3383	formate dehydrogenase (NAD+) activity
At15955_RS22505	COG2223	nitrite transmembrane transporter activity
At15955_RS22510	COG0456	acetyltransferase
At15955_RS22540	COG3237	CsbD-like
At15955_RS22545	COG2197	response regulator
At15955_RS22550	COG3181	Tripartite tricarboxylate transporter family receptor
At15955_RS22555	COG5265	(ABC) transporter
At15955_RS22560	COG0640	Transcriptional regulator
At15955_RS22570	COG4943	cyclic-guanylate-specific phosphodiesterase activity
At15955_RS22580	COG0753	catalase activity
At15955_RS22625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
At15955_RS22645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
At15955_RS22650	COG2203	Gaf domain
At15955_RS22650	COG4251	negative regulation of phosphorylation
At15955_RS22650	COG5001	Diguanylate cyclase
At15955_RS22650	COG3706	GGDEF domain
At15955_RS22660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
At15955_RS22665	COG3046	protein related to deoxyribodipyrimidine photolyase
At15955_RS22710	COG1595	DNA-templated transcription, initiation
At15955_RS22720	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS22725	COG1309	transcriptional regulator
At15955_RS22735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
At15955_RS22750	COG1126	abc transporter atp-binding protein
At15955_RS22755	COG0765	amino acid transport
At15955_RS22760	COG0765	amino acid transport
At15955_RS22765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS22770	COG3608	succinylglutamate desuccinylase aspartoacylase
At15955_RS22775	COG0006	proline dipeptidase activity
At15955_RS22780	COG2423	ornithine cyclodeaminase activity
At15955_RS22785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
At15955_RS22790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
At15955_RS22795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
At15955_RS22805	COG1522	sequence-specific DNA binding
At15955_RS23035	COG4106	trans-aconitate 2-methyltransferase activity
At15955_RS23055	COG2814	Major facilitator Superfamily
At15955_RS23060	COG0583	DNA-binding transcription factor activity
At15955_RS23085	COG0747	negative chemotaxis
At15955_RS23090	COG0601	transmembrane transport
At15955_RS23095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS23100	COG4172	Belongs to the ABC transporter superfamily
At15955_RS23115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
At15955_RS23180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
At15955_RS23190	COG0406	alpha-ribazole phosphatase activity
At15955_RS23260	COG0583	DNA-binding transcription factor activity
At15955_RS23275	COG3657	addiction module killer protein
At15955_RS23310	COG1475	DNA binding
At15955_RS23315	COG0640	Transcriptional regulator
At15955_RS23325	COG3077	Addiction module antitoxin, RelB DinJ family
At15955_RS23360	COG3971	2-oxopent-4-enoate hydratase activity
At15955_RS23365	COG3485	protocatechuate 3,4-dioxygenase
At15955_RS23495	COG3620	sequence-specific DNA binding
At15955_RS23500	COG3550	peptidyl-serine autophosphorylation
At15955_RS23510	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS23535	COG2072	flavoprotein involved in K transport
At15955_RS23545	COG2144	transferase activity, transferring acyl groups
At15955_RS23555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
At15955_RS23570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
At15955_RS23585	COG1309	transcriptional regulator
At15955_RS23590	COG1794	racemase activity, acting on amino acids and derivatives
At15955_RS23600	COG0402	S-adenosylhomocysteine deaminase activity
At15955_RS23620	COG1116	anion transmembrane transporter activity
At15955_RS23665	COG4221	oxidoreductase activity
At15955_RS23710	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS23720	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS23735	COG1741	Belongs to the pirin family
At15955_RS23740	COG0583	DNA-binding transcription factor activity
At15955_RS23760	COG0583	DNA-binding transcription factor activity
At15955_RS23770	COG0235	Class ii aldolase
At15955_RS23775	COG0583	DNA-binding transcription factor activity
At15955_RS23780	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS23815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
At15955_RS23825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
At15955_RS23840	COG0667	Aldo Keto reductase
At15955_RS23885	COG1802	Transcriptional regulator
At15955_RS23915	COG3547	Transposase (IS116 IS110 IS902 family)
At15955_RS23920	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
At15955_RS23940	COG3609	addiction module antidote protein, CC2985 family
At15955_RS24000	COG3177	Filamentation induced by cAMP protein fic
At15955_RS24045	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS24055	COG0583	DNA-binding transcription factor activity
At15955_RS24060	COG3842	ATPase activity
At15955_RS24070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS24080	COG1176	ABC-type spermidine putrescine transport system, permease component I
At15955_RS24085	COG4208	sulfate ABC transporter
At15955_RS24110	COG1764	response to oxidative stress
At15955_RS24150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At15955_RS24155	COG1301	dicarboxylic acid transport
At15955_RS24165	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
At15955_RS24170	COG1653	transport
At15955_RS24175	COG1175	transmembrane transport
At15955_RS24190	COG3842	ATPase activity
At15955_RS24200	COG0583	DNA-binding transcription factor activity
At15955_RS24225	COG1846	Transcriptional regulator
At15955_RS24235	COG1335	isochorismatase
At15955_RS24245	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS24250	COG2207	Transcriptional regulator
At15955_RS24265	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
At15955_RS24275	COG3842	ATPase activity
At15955_RS24280	COG1840	ABC-type Fe3 transport system, periplasmic component
At15955_RS24285	COG1176	ABC-type spermidine putrescine transport system, permease component I
At15955_RS24305	COG0559	Belongs to the binding-protein-dependent transport system permease family
At15955_RS24320	COG1228	amidohydrolase
At15955_RS24345	COG0840	transmembrane signaling receptor activity
At15955_RS24360	COG4691	Plasmid stability protein
At15955_RS24365	COG1487	ribonuclease activity
At15955_RS24370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At15955_RS24380	COG2186	Transcriptional regulator
At15955_RS24385	COG0747	negative chemotaxis
At15955_RS24390	COG0601	transmembrane transport
At15955_RS24395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS24400	COG4172	Belongs to the ABC transporter superfamily
At15955_RS24405	COG4948	Mandelate Racemase Muconate Lactonizing
At15955_RS24445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At15955_RS24465	COG0598	Magnesium transport protein CorA
At15955_RS24470	COG1597	lipid kinase activity
At15955_RS24475	COG2354	Protein conserved in bacteria
At15955_RS24500	COG0577	efflux transmembrane transporter activity
At15955_RS24515	COG1414	Transcriptional regulator
At15955_RS24525	COG1454	alcohol dehydrogenase
At15955_RS24545	COG0456	acetyltransferase
At15955_RS24545	COG0454	-acetyltransferase
At15955_RS24560	COG3436	PFAM IS66 Orf2 family protein
At15955_RS24565	COG4372	Transposase
At15955_RS24630	COG0784	Response regulator, receiver
At15955_RS24630	COG4191	Histidine kinase
At15955_RS24640	COG3547	Transposase (IS116 IS110 IS902 family)
At15955_RS24655	COG1120	ATPase activity
At15955_RS24660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS24665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS24670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
At15955_RS24675	COG1629	transport
At15955_RS24675	COG4774	siderophore transport
At15955_RS24685	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
At15955_RS24695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
At15955_RS24730	COG2226	methyltransferase
At15955_RS24745	COG0318	PFAM AMP-dependent synthetase and ligase
At15955_RS24765	COG0534	Mate efflux family protein
At15955_RS24775	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
At15955_RS24795	COG3734	2-keto-3-deoxy-galactonokinase
At15955_RS24800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At15955_RS24805	COG4948	Mandelate Racemase Muconate Lactonizing
At15955_RS24815	COG1175	transmembrane transport
At15955_RS24820	COG0395	ABC-type sugar transport system, permease component
At15955_RS24825	COG3842	ATPase activity
At15955_RS24835	COG1414	Transcriptional regulator
At15955_RS24840	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS24845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
At15955_RS24850	COG2207	Transcriptional regulator
At15955_RS24865	COG0583	DNA-binding transcription factor activity
At15955_RS24870	COG0667	Aldo Keto reductase
At15955_RS24875	COG0583	DNA-binding transcription factor activity
At15955_RS24890	COG1609	Transcriptional regulator
At15955_RS24895	COG1082	Xylose isomerase domain protein TIM barrel
At15955_RS24900	COG0673	inositol 2-dehydrogenase activity
At15955_RS24905	COG1082	Xylose isomerase domain protein TIM barrel
At15955_RS24915	COG0405	Gamma-glutamyltransferase
At15955_RS24925	COG1120	ATPase activity
At15955_RS24940	COG4774	siderophore transport
At15955_RS24960	COG1215	transferase activity, transferring glycosyl groups
At15955_RS24995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
At15955_RS25010	COG2390	Transcriptional regulator
At15955_RS25015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
At15955_RS25020	COG3958	Transketolase
At15955_RS25025	COG3959	Transketolase, thiamine diphosphate binding domain
At15955_RS25030	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS25040	COG1129	ABC transporter
At15955_RS25045	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS25050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
At15955_RS25060	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
At15955_RS25080	COG0477	Major facilitator Superfamily
At15955_RS25100	COG1126	abc transporter atp-binding protein
At15955_RS25105	COG0765	amino acid transport
At15955_RS25110	COG0765	amino acid transport
At15955_RS25115	COG1741	Belongs to the pirin family
At15955_RS25120	COG1335	isochorismatase
At15955_RS25130	COG1733	regulation of RNA biosynthetic process
At15955_RS25135	COG0604	alcohol dehydrogenase
At15955_RS25135	COG3321	synthase
At15955_RS25135	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS25140	COG0583	DNA-binding transcription factor activity
At15955_RS25160	COG1017	nitric oxide dioxygenase activity
At15955_RS25160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
At15955_RS25165	COG0625	glutathione transferase activity
At15955_RS25175	COG0583	DNA-binding transcription factor activity
At15955_RS25190	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
At15955_RS25195	COG2202	Pas domain
At15955_RS25195	COG3920	Histidine kinase
At15955_RS25260	COG1285	pathogenesis
At15955_RS25280	COG4166	transmembrane transport
At15955_RS25285	COG0601	transmembrane transport
At15955_RS25290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS25300	COG2843	Capsule synthesis protein
At15955_RS25305	COG2195	Cleaves the N-terminal amino acid of tripeptides
At15955_RS25320	COG4962	Type ii secretion system protein e
At15955_RS25335	COG3451	type IV secretory pathway VirB4
At15955_RS25340	COG5314	conjugation
At15955_RS25350	COG3846	protein secretion by the type IV secretion system
At15955_RS25355	COG3701	Conjugal transfer protein
At15955_RS25385	COG1902	pentaerythritol trinitrate reductase activity
At15955_RS25390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At15955_RS25415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
At15955_RS25420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
At15955_RS25435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At15955_RS25460	COG0667	Aldo Keto reductase
At15955_RS25475	COG0673	inositol 2-dehydrogenase activity
At15955_RS25485	COG0395	ABC-type sugar transport system, permease component
At15955_RS25490	COG1175	transmembrane transport
At15955_RS25495	COG3842	ATPase activity
At15955_RS25520	COG3547	Transposase (IS116 IS110 IS902 family)
At15955_RS25535	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS25545	COG1879	ABC-type sugar transport system periplasmic component
At15955_RS25550	COG1879	ABC-type sugar transport system periplasmic component
At15955_RS25555	COG0246	Mannitol dehydrogenase
At15955_RS25565	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS25570	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS25580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
At15955_RS25595	COG1609	Transcriptional regulator
At15955_RS25600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
At15955_RS25635	COG1070	Carbohydrate kinase
At15955_RS25645	COG1175	transmembrane transport
At15955_RS25650	COG0395	ABC-type sugar transport system, permease component
At15955_RS25665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
At15955_RS25675	COG0508	dehydrogenase complex catalyzes the overall conversion of
At15955_RS25675	COG0596	Alpha beta hydrolase
At15955_RS25700	COG0402	S-adenosylhomocysteine deaminase activity
At15955_RS25715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At15955_RS25750	COG3436	PFAM IS66 Orf2 family protein
At15955_RS25755	COG4372	Transposase
At15955_RS25760	COG0183	Belongs to the thiolase family
At15955_RS25765	COG1024	Enoyl-CoA hydratase
At15955_RS25775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
At15955_RS25785	COG0477	Major facilitator Superfamily
At15955_RS25795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS25800	COG1902	pentaerythritol trinitrate reductase activity
At15955_RS25825	COG1621	beta-fructofuranosidase activity
At15955_RS25845	COG0395	ABC-type sugar transport system, permease component
At15955_RS25850	COG1175	transmembrane transport
At15955_RS25855	COG1653	transport
At15955_RS25860	COG1609	Transcriptional regulator
At15955_RS25865	COG2801	Transposase and inactivated derivatives
At15955_RS25880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
At15955_RS25910	COG2207	Transcriptional regulator
At15955_RS25920	COG0840	transmembrane signaling receptor activity
At15955_RS25930	COG4607	ABC-type enterochelin transport system periplasmic component
At15955_RS25935	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS25940	COG4605	iron ion homeostasis
At15955_RS25945	COG4604	ABC transporter, ATP-binding protein
At15955_RS26020	COG3831	ATPase activity
At15955_RS26025	COG5489	Protein of unknown function (DUF736)
At15955_RS26060	COG1475	DNA binding
At15955_RS26105	COG0587	DNA-directed DNA polymerase activity
At15955_RS26135	COG1522	sequence-specific DNA binding
At15955_RS26160	COG1846	Transcriptional regulator
At15955_RS26165	COG2807	transmembrane transport
At15955_RS26170	COG2211	Major facilitator Superfamily
At15955_RS26185	COG0583	DNA-binding transcription factor activity
At15955_RS26190	COG1309	transcriptional regulator
At15955_RS26200	COG2020	methyltransferase activity
At15955_RS26210	COG4948	Mandelate Racemase Muconate Lactonizing
At15955_RS26220	COG1802	Transcriptional regulator
At15955_RS26225	COG0747	negative chemotaxis
At15955_RS26230	COG0601	transmembrane transport
At15955_RS26235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS26245	COG4608	Belongs to the ABC transporter superfamily
At15955_RS26265	COG1609	Transcriptional regulator
At15955_RS26275	COG0583	DNA-binding transcription factor activity
At15955_RS26300	COG5002	protein histidine kinase activity
At15955_RS26305	COG1404	Belongs to the peptidase S8 family
At15955_RS26340	COG1929	Belongs to the glycerate kinase type-1 family
At15955_RS26370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At15955_RS26375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
At15955_RS26395	COG0583	DNA-binding transcription factor activity
At15955_RS26405	COG0583	DNA-binding transcription factor activity
At15955_RS26415	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
At15955_RS26430	COG0583	DNA-binding transcription factor activity
At15955_RS26435	COG3547	Transposase (IS116 IS110 IS902 family)
At15955_RS26445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At15955_RS26450	COG0842	Transport permease protein
At15955_RS26450	COG1129	ABC transporter
At15955_RS26455	COG0842	Transport permease protein
At15955_RS26460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
At15955_RS26465	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
At15955_RS26485	COG0668	transmembrane transport
At15955_RS26490	COG1012	belongs to the aldehyde dehydrogenase family
At15955_RS26495	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS26500	COG0583	DNA-binding transcription factor activity
At15955_RS26520	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS26555	COG4175	Glycine betaine
At15955_RS26555	COG0517	IMP dehydrogenase activity
At15955_RS26560	COG4176	ABC-type proline glycine betaine transport system permease component
At15955_RS26570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
At15955_RS26580	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
At15955_RS26600	COG1414	Transcriptional regulator
At15955_RS26605	COG0410	ABC transporter
At15955_RS26685	COG0531	amino acid
At15955_RS26710	COG1129	ABC transporter
At15955_RS26715	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS26720	COG1879	ABC-type sugar transport system periplasmic component
At15955_RS26725	COG0673	inositol 2-dehydrogenase activity
At15955_RS26730	COG1082	Xylose isomerase domain protein TIM barrel
At15955_RS26740	COG3962	Belongs to the TPP enzyme family
At15955_RS26745	COG3718	enzyme involved in inositol metabolism
At15955_RS26750	COG1942	4-Oxalocrotonate Tautomerase
At15955_RS26780	COG1132	(ABC) transporter
At15955_RS26810	COG0747	negative chemotaxis
At15955_RS26815	COG0601	transmembrane transport
At15955_RS26825	COG4172	Belongs to the ABC transporter superfamily
At15955_RS26830	COG1349	DNA-binding transcription factor activity
At15955_RS26835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
At15955_RS26870	COG2207	Transcriptional regulator
At15955_RS26895	COG1566	PFAM secretion protein HlyD family protein
At15955_RS26910	COG0668	transmembrane transport
At15955_RS26965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
At15955_RS26970	COG1280	lysine exporter protein (LysE YggA)
At15955_RS26980	COG1012	belongs to the aldehyde dehydrogenase family
At15955_RS27000	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS27005	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS27010	COG1129	ABC transporter
At15955_RS27015	COG1879	ABC-type sugar transport system periplasmic component
At15955_RS27035	COG1120	ATPase activity
At15955_RS27040	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS27045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At15955_RS27055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
At15955_RS27060	COG4774	siderophore transport
At15955_RS27080	COG0583	DNA-binding transcription factor activity
At15955_RS27085	COG0667	Aldo Keto reductase
At15955_RS27115	COG1172	Belongs to the binding-protein-dependent transport system permease family
At15955_RS27150	COG1278	Cold shock
At15955_RS27160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
At15955_RS27165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At15955_RS27180	COG1538	Outer membrane efflux protein
At15955_RS27200	COG1126	abc transporter atp-binding protein
At15955_RS27205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At15955_RS27210	COG1609	Transcriptional regulator
At15955_RS27215	COG1192	Involved in chromosome partitioning
At15955_RS27220	COG1475	DNA binding
At15955_RS27225	COG0640	Transcriptional regulator
At15955_RS27475	COG4372	Transposase
At15955_RS27480	COG3436	PFAM IS66 Orf2 family protein
At15955_RS27485	COG2963	transposase activity
At15955_RS27555	COG1278	Cold shock
At15955_RS27595	COG0546	phosphoglycolate phosphatase activity
At15955_RS27715	COG2222	sugar isomerase
At15955_RS27725	COG0006	proline dipeptidase activity
At15955_RS27820	COG4172	Belongs to the ABC transporter superfamily
At15955_RS27825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS27830	COG0601	transmembrane transport
At15955_RS27910	COG1177	transmembrane transport
At15955_RS27915	COG1176	ABC-type spermidine putrescine transport system, permease component I
At15955_RS27930	COG0840	transmembrane signaling receptor activity
At15955_RS27930	COG2972	Histidine kinase
At15955_RS27945	COG3842	ATPase activity
At15955_RS27950	COG0006	proline dipeptidase activity
At15955_RS27970	COG0300	oxidoreductase activity
At15955_RS27975	COG0129	dihydroxy-acid dehydratase activity
At15955_RS27980	COG0667	Aldo Keto reductase
At15955_RS27990	COG1028	Short-chain dehydrogenase reductase Sdr
At15955_RS28000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS28005	COG0601	transmembrane transport
At15955_RS28010	COG4172	Belongs to the ABC transporter superfamily
At15955_RS28020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At15955_RS28060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At15955_RS28065	COG4172	Belongs to the ABC transporter superfamily
At15955_RS28090	COG3701	Conjugal transfer protein
At15955_RS28095	COG3846	protein secretion by the type IV secretion system
At15955_RS28105	COG5314	conjugation
At15955_RS28110	COG3451	type IV secretory pathway VirB4
At15955_RS28125	COG4962	Type ii secretion system protein e