locus-tag	class	description
CFBP5499_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFBP5499_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP5499_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFBP5499_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFBP5499_RS00025	COG1420	regulation of RNA biosynthetic process
CFBP5499_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFBP5499_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP5499_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFBP5499_RS00050	COG1137	ATPase activity
CFBP5499_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CFBP5499_RS00065	COG0616	signal peptide processing
CFBP5499_RS00070	COG0776	regulation of translation
CFBP5499_RS00080	COG0116	Belongs to the methyltransferase superfamily
CFBP5499_RS00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CFBP5499_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP5499_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFBP5499_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFBP5499_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFBP5499_RS00115	COG0728	peptidoglycan biosynthetic process
CFBP5499_RS00125	COG0180	Tryptophanyl-tRNA synthetase
CFBP5499_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CFBP5499_RS00140	COG1214	PFAM Peptidase M22, glycoprotease
CFBP5499_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP5499_RS00165	COG1702	phosphate starvation-inducible protein PhoH
CFBP5499_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFBP5499_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CFBP5499_RS00185	COG1396	sequence-specific DNA binding
CFBP5499_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFBP5499_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFBP5499_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_RS00210	COG0242	peptide deformylase activity
CFBP5499_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFBP5499_RS00220	COG0101	tRNA pseudouridine synthase activity
CFBP5499_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP5499_RS00235	COG2171	N-acyltransferase activity
CFBP5499_RS00245	COG0840	transmembrane signaling receptor activity
CFBP5499_RS00255	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP5499_RS00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFBP5499_RS00295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CFBP5499_RS00300	COG0706	membrane insertase activity
CFBP5499_RS00305	COG0594	ribonuclease P activity
CFBP5499_RS00310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFBP5499_RS00320	COG0840	transmembrane signaling receptor activity
CFBP5499_RS00325	COG3850	Histidine kinase
CFBP5499_RS00325	COG5002	protein histidine kinase activity
CFBP5499_RS00340	COG2226	methyltransferase
CFBP5499_RS00355	COG3842	ATPase activity
CFBP5499_RS00360	COG1175	transmembrane transport
CFBP5499_RS00365	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS00380	COG0427	acetyl-CoA hydrolase
CFBP5499_RS00390	COG3938	Belongs to the proline racemase family
CFBP5499_RS00395	COG0418	dihydroorotase activity
CFBP5499_RS00400	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFBP5499_RS00420	COG0166	Belongs to the GPI family
CFBP5499_RS00425	COG0318	PFAM AMP-dependent synthetase and ligase
CFBP5499_RS00430	COG3842	ATPase activity
CFBP5499_RS00435	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_RS00440	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP5499_RS00445	COG4774	siderophore transport
CFBP5499_RS00495	COG2326	polyphosphate kinase activity
CFBP5499_RS00500	COG5002	protein histidine kinase activity
CFBP5499_RS00505	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFBP5499_RS00510	COG0573	inorganic phosphate transmembrane transporter activity
CFBP5499_RS00520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFBP5499_RS00525	COG0704	Plays a role in the regulation of phosphate uptake
CFBP5499_RS00530	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS00545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFBP5499_RS00550	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFBP5499_RS00560	COG2967	ApaG domain
CFBP5499_RS00570	COG0717	Belongs to the dCTP deaminase family
CFBP5499_RS00595	COG0753	catalase activity
CFBP5499_RS00600	COG3685	Protein conserved in bacteria
CFBP5499_RS00650	COG1573	uracil-dna glycosylase
CFBP5499_RS00685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFBP5499_RS00735	COG0167	dihydroorotate dehydrogenase activity
CFBP5499_RS00750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP5499_RS00770	COG1959	2 iron, 2 sulfur cluster binding
CFBP5499_RS00775	COG1201	RNA secondary structure unwinding
CFBP5499_RS00795	COG0730	response to heat
CFBP5499_RS00810	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_RS00815	COG0183	Belongs to the thiolase family
CFBP5499_RS00820	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP5499_RS00820	COG1024	Enoyl-CoA hydratase
CFBP5499_RS01100	COG0740	serine-type endopeptidase activity
CFBP5499_RS01200	COG2755	lipolytic protein G-D-S-L family
CFBP5499_RS01200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP5499_RS01290	COG1320	monovalent cation:proton antiporter activity
CFBP5499_RS01295	COG2212	antiporter activity
CFBP5499_RS01300	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP5499_RS01305	COG0651	ATP synthesis coupled electron transport
CFBP5499_RS01310	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP5499_RS01315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFBP5499_RS01315	COG2111	Na H antiporter
CFBP5499_RS01325	COG0840	transmembrane signaling receptor activity
CFBP5499_RS01335	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS01340	COG0643	Histidine kinase
CFBP5499_RS01340	COG2198	Histidine kinase
CFBP5499_RS01345	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CFBP5499_RS01350	COG2201	protein-glutamate methylesterase activity
CFBP5499_RS01355	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS01360	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CFBP5499_RS01370	COG1766	The M ring may be actively involved in energy transduction
CFBP5499_RS01375	COG2771	luxR family
CFBP5499_RS01385	COG0840	transmembrane signaling receptor activity
CFBP5499_RS01385	COG2972	Histidine kinase
CFBP5499_RS01390	COG0784	Response regulator, receiver
CFBP5499_RS01390	COG2205	protein histidine kinase activity
CFBP5499_RS01390	COG2198	Histidine kinase
CFBP5499_RS01395	COG1970	mechanosensitive ion channel activity
CFBP5499_RS01400	COG0436	Aminotransferase
CFBP5499_RS01415	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CFBP5499_RS01420	COG0424	maF-like protein
CFBP5499_RS01425	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFBP5499_RS01435	COG5328	Belongs to the UPF0262 family
CFBP5499_RS01440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFBP5499_RS01450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFBP5499_RS01470	COG1431	PFAM Stem cell self-renewal protein Piwi
CFBP5499_RS01485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP5499_RS01495	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP5499_RS01510	COG0110	maltose O-acetyltransferase activity
CFBP5499_RS01530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP5499_RS01565	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
CFBP5499_RS01575	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFBP5499_RS01660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP5499_RS01700	COG1338	Plays a role in the flagellum-specific transport system
CFBP5499_RS01710	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CFBP5499_RS01720	COG1706	bacterial-type flagellum-dependent cell motility
CFBP5499_RS01725	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CFBP5499_RS01730	COG4786	Flagellar basal body rod
CFBP5499_RS01735	COG1677	Flagellar hook-basal body complex protein FliE
CFBP5499_RS01740	COG1558	bacterial-type flagellum-dependent cell motility
CFBP5499_RS01745	COG1815	bacterial-type flagellum-dependent cell motility
CFBP5499_RS01750	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_RS01760	COG1157	protein secretion by the type III secretion system
CFBP5499_RS01765	COG4786	Flagellar basal body rod
CFBP5499_RS01775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CFBP5499_RS01780	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP5499_RS01785	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP5499_RS01790	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP5499_RS01795	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP5499_RS01820	COG1360	Flagellar Motor Protein
CFBP5499_RS01845	COG1749	Flagellar hook protein flgE
CFBP5499_RS01865	COG5443	negative regulation of bacterial-type flagellum assembly
CFBP5499_RS01870	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CFBP5499_RS01880	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP5499_RS01920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFBP5499_RS01925	COG1609	Transcriptional regulator
CFBP5499_RS01930	COG1653	transport
CFBP5499_RS01935	COG1175	transmembrane transport
CFBP5499_RS01940	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS01945	COG0366	Alpha amylase catalytic
CFBP5499_RS01950	COG3842	ATPase activity
CFBP5499_RS01965	COG0129	dihydroxy-acid dehydratase activity
CFBP5499_RS01970	COG0363	glucosamine-6-phosphate deaminase activity
CFBP5499_RS01975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFBP5499_RS01985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS01995	COG2081	HI0933 family
CFBP5499_RS02015	COG2224	Isocitrate lyase
CFBP5499_RS02030	COG3842	ATPase activity
CFBP5499_RS02035	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_RS02040	COG1177	transmembrane transport
CFBP5499_RS02050	COG2205	protein histidine kinase activity
CFBP5499_RS02060	COG0248	Ppx GppA phosphatase
CFBP5499_RS02065	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CFBP5499_RS02070	COG0477	Major facilitator Superfamily
CFBP5499_RS02110	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFBP5499_RS02115	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFBP5499_RS02125	COG0142	geranyltranstransferase activity
CFBP5499_RS02150	COG0752	glycyl-tRNA synthetase alpha subunit
CFBP5499_RS02155	COG1704	LemA family
CFBP5499_RS02160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFBP5499_RS02170	COG0751	glycine-tRNA ligase activity
CFBP5499_RS02180	COG1683	Conserved Protein
CFBP5499_RS02185	COG0840	transmembrane signaling receptor activity
CFBP5499_RS02195	COG0151	Belongs to the GarS family
CFBP5499_RS02200	COG2183	response to ionizing radiation
CFBP5499_RS02205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP5499_RS02230	COG0583	DNA-binding transcription factor activity
CFBP5499_RS02250	COG0306	phosphate transporter
CFBP5499_RS02265	COG0561	phosphatase activity
CFBP5499_RS02270	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_RS02275	COG2186	Transcriptional regulator
CFBP5499_RS02285	COG0583	DNA-binding transcription factor activity
CFBP5499_RS02290	COG0277	FAD linked oxidase domain protein
CFBP5499_RS02295	COG0277	FAD linked oxidase domain protein
CFBP5499_RS02300	COG0247	lactate metabolic process
CFBP5499_RS02310	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_RS02315	COG2818	Glycosylase
CFBP5499_RS02325	COG2855	membrane
CFBP5499_RS02330	COG0583	DNA-binding transcription factor activity
CFBP5499_RS02350	COG0124	histidyl-tRNA synthetase
CFBP5499_RS02360	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFBP5499_RS02365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFBP5499_RS02370	COG2259	Doxx family
CFBP5499_RS02385	COG0459	protein refolding
CFBP5499_RS02390	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFBP5499_RS02400	COG0196	riboflavin kinase activity
CFBP5499_RS02405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFBP5499_RS02415	COG0590	tRNA wobble adenosine to inosine editing
CFBP5499_RS02420	COG1187	pseudouridine synthase activity
CFBP5499_RS02425	COG0742	ribosomal rna small subunit methyltransferase
CFBP5499_RS02430	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP5499_RS02435	COG0475	glutathione-regulated potassium exporter activity
CFBP5499_RS02435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP5499_RS02445	COG0312	modulator of DNA gyrase
CFBP5499_RS02450	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_RS02460	COG1519	Transferase
CFBP5499_RS02470	COG1663	tetraacyldisaccharide 4'-kinase activity
CFBP5499_RS02480	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFBP5499_RS02485	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS02490	COG5001	Diguanylate cyclase
CFBP5499_RS02490	COG3300	MHYT domain
CFBP5499_RS02495	COG3386	PFAM SMP-30 Gluconolaconase
CFBP5499_RS02500	COG0800	Aldolase
CFBP5499_RS02505	COG3734	2-keto-3-deoxy-galactonokinase
CFBP5499_RS02510	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS02520	COG2197	response regulator
CFBP5499_RS02525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_RS02535	COG0598	Magnesium transport protein CorA
CFBP5499_RS02540	COG3158	transport of potassium into the cell
CFBP5499_RS02555	COG0356	it plays a direct role in the translocation of protons across the membrane
CFBP5499_RS02565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP5499_RS02570	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP5499_RS02585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFBP5499_RS02605	COG0009	L-threonylcarbamoyladenylate synthase
CFBP5499_RS02615	COG4638	Rieske (2fe-2S)
CFBP5499_RS02640	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_RS02655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFBP5499_RS02660	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CFBP5499_RS02665	COG0840	transmembrane signaling receptor activity
CFBP5499_RS02675	COG1522	sequence-specific DNA binding
CFBP5499_RS02705	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFBP5499_RS02710	COG1741	Belongs to the pirin family
CFBP5499_RS02715	COG1722	exodeoxyribonuclease VII activity
CFBP5499_RS02720	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFBP5499_RS02725	COG1268	BioY protein
CFBP5499_RS02730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFBP5499_RS02735	COG1122	ATPase activity
CFBP5499_RS02740	COG3214	Protein conserved in bacteria
CFBP5499_RS02745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP5499_RS02745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP5499_RS02750	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFBP5499_RS02770	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP5499_RS02785	COG0259	pyridoxamine-phosphate oxidase activity
CFBP5499_RS02800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5499_RS02810	COG0312	modulator of DNA gyrase
CFBP5499_RS02830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP5499_RS02835	COG0109	protoheme IX farnesyltransferase activity
CFBP5499_RS02845	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CFBP5499_RS02860	COG3346	SURF1 family
CFBP5499_RS02865	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CFBP5499_RS02870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFBP5499_RS02875	COG0328	RNA-DNA hybrid ribonuclease activity
CFBP5499_RS02890	COG0678	peroxiredoxin activity
CFBP5499_RS02890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFBP5499_RS02900	COG1678	Uncharacterized ACR, COG1678
CFBP5499_RS02915	COG5001	Diguanylate cyclase
CFBP5499_RS02915	COG3300	MHYT domain
CFBP5499_RS02920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP5499_RS02925	COG0612	Peptidase, M16
CFBP5499_RS02940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5499_RS02945	COG1802	Transcriptional regulator
CFBP5499_RS02965	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CFBP5499_RS02975	COG3609	addiction module antidote protein, CC2985 family
CFBP5499_RS02990	COG1194	a g-specific adenine glycosylase
CFBP5499_RS03005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFBP5499_RS03010	COG1196	nuclear chromosome segregation
CFBP5499_RS03020	COG2514	catechol 2,3-dioxygenase activity
CFBP5499_RS03025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFBP5499_RS03025	COG0574	Belongs to the PEP-utilizing enzyme family
CFBP5499_RS03035	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CFBP5499_RS03040	COG1823	symporter activity
CFBP5499_RS03070	COG0579	oxidoreductase
CFBP5499_RS03095	COG2895	sulfate adenylyltransferase (ATP) activity
CFBP5499_RS03100	COG0175	sulfate reduction
CFBP5499_RS03105	COG0175	sulfate reduction
CFBP5499_RS03110	COG1959	2 iron, 2 sulfur cluster binding
CFBP5499_RS03115	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CFBP5499_RS03120	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP5499_RS03125	COG4208	sulfate ABC transporter
CFBP5499_RS03130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP5499_RS03145	COG2199	diguanylate cyclase activity
CFBP5499_RS03145	COG2200	EAL domain
CFBP5499_RS03145	COG2203	Gaf domain
CFBP5499_RS03155	COG1309	transcriptional regulator
CFBP5499_RS03160	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS03170	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CFBP5499_RS03215	COG0477	Major facilitator Superfamily
CFBP5499_RS03225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CFBP5499_RS03225	COG1793	dna ligase
CFBP5499_RS03240	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_RS03245	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_RS03255	COG1846	Transcriptional regulator
CFBP5499_RS03260	COG1764	response to oxidative stress
CFBP5499_RS03275	COG0488	(ABC) transporter
CFBP5499_RS03305	COG0583	DNA-binding transcription factor activity
CFBP5499_RS03310	COG4221	oxidoreductase activity
CFBP5499_RS03320	COG0433	COG0433 Predicted ATPase
CFBP5499_RS03335	COG1733	regulation of RNA biosynthetic process
CFBP5499_RS03340	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CFBP5499_RS03350	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_RS03355	COG0656	L-ascorbic acid biosynthetic process
CFBP5499_RS03360	COG4106	trans-aconitate 2-methyltransferase activity
CFBP5499_RS03365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP5499_RS03370	COG0840	transmembrane signaling receptor activity
CFBP5499_RS03375	COG0583	DNA-binding transcription factor activity
CFBP5499_RS03390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP5499_RS03400	COG2378	regulation of single-species biofilm formation
CFBP5499_RS03410	COG3909	cytochrome
CFBP5499_RS03415	COG2010	Cytochrome c
CFBP5499_RS03450	COG0789	Transcriptional regulator
CFBP5499_RS03475	COG0517	IMP dehydrogenase activity
CFBP5499_RS03475	COG4175	Glycine betaine
CFBP5499_RS03480	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_RS03510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_RS03520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP5499_RS03520	COG2169	Transcriptional regulator
CFBP5499_RS03530	COG2514	catechol 2,3-dioxygenase activity
CFBP5499_RS03550	COG1272	protein, Hemolysin III
CFBP5499_RS03560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP5499_RS03565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFBP5499_RS03565	COG2111	Na H antiporter
CFBP5499_RS03570	COG2111	Na H antiporter
CFBP5499_RS03575	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP5499_RS03580	COG0651	ATP synthesis coupled electron transport
CFBP5499_RS03585	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP5499_RS03590	COG2212	antiporter activity
CFBP5499_RS03595	COG1320	monovalent cation:proton antiporter activity
CFBP5499_RS03600	COG4957	zinc ion binding
CFBP5499_RS03615	COG2166	iron-sulfur cluster assembly
CFBP5499_RS03625	COG2205	protein histidine kinase activity
CFBP5499_RS03680	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP5499_RS03685	COG2983	Belongs to the UPF0260 family
CFBP5499_RS03730	COG2814	Major facilitator Superfamily
CFBP5499_RS03740	COG1621	beta-fructofuranosidase activity
CFBP5499_RS03745	COG2202	Pas domain
CFBP5499_RS03745	COG3920	Histidine kinase
CFBP5499_RS03750	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFBP5499_RS03800	COG4695	Portal protein
CFBP5499_RS03915	COG4235	cytochrome complex assembly
CFBP5499_RS03920	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CFBP5499_RS03925	COG1138	Cytochrome C-type biogenesis protein
CFBP5499_RS03930	COG3088	subunit of a heme lyase
CFBP5499_RS03935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP5499_RS03940	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS03945	COG2205	protein histidine kinase activity
CFBP5499_RS03950	COG3011	Protein conserved in bacteria
CFBP5499_RS03960	COG3713	MltA-interacting MipA family protein
CFBP5499_RS03965	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFBP5499_RS03975	COG2205	protein histidine kinase activity
CFBP5499_RS03975	COG2202	Pas domain
CFBP5499_RS03985	COG0308	aminopeptidase N
CFBP5499_RS03990	COG0697	spore germination
CFBP5499_RS04010	COG0443	Heat shock 70 kDa protein
CFBP5499_RS04015	COG2199	diguanylate cyclase activity
CFBP5499_RS04015	COG2203	Gaf domain
CFBP5499_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS04040	COG1733	regulation of RNA biosynthetic process
CFBP5499_RS04055	COG0604	alcohol dehydrogenase
CFBP5499_RS04060	COG1733	regulation of RNA biosynthetic process
CFBP5499_RS04065	COG1968	undecaprenyl-diphosphatase activity
CFBP5499_RS04070	COG2239	Acts as a magnesium transporter
CFBP5499_RS04075	COG2814	Major facilitator Superfamily
CFBP5499_RS04105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFBP5499_RS04130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP5499_RS04135	COG2132	Multicopper oxidase
CFBP5499_RS04200	COG1802	Transcriptional regulator
CFBP5499_RS04200	COG4626	Terminase
CFBP5499_RS04285	COG0582	viral genome integration into host DNA
CFBP5499_RS04310	COG0741	lytic transglycosylase activity
CFBP5499_RS04320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_RS04325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFBP5499_RS04335	COG0840	transmembrane signaling receptor activity
CFBP5499_RS04345	COG1758	RNA polymerase activity
CFBP5499_RS04370	COG0736	holo-[acyl-carrier-protein] synthase activity
CFBP5499_RS04375	COG0681	Belongs to the peptidase S26 family
CFBP5499_RS04380	COG0571	ribonuclease III activity
CFBP5499_RS04385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFBP5499_RS04390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP5499_RS04395	COG0784	Response regulator, receiver
CFBP5499_RS04400	COG1381	Involved in DNA repair and RecF pathway recombination
CFBP5499_RS04410	COG2226	methyltransferase
CFBP5499_RS04420	COG1418	mRNA catabolic process
CFBP5499_RS04430	COG0346	lactoylglutathione lyase activity
CFBP5499_RS04440	COG1116	anion transmembrane transporter activity
CFBP5499_RS04445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_RS04450	COG3443	Belongs to the bacterial solute-binding protein 9 family
CFBP5499_RS04455	COG0668	transmembrane transport
CFBP5499_RS04465	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CFBP5499_RS04495	COG1742	UPF0060 membrane protein
CFBP5499_RS04515	COG1183	phosphatidylcholine synthase activity
CFBP5499_RS04520	COG0688	phosphatidylethanolamine metabolic process
CFBP5499_RS04525	COG5265	(ABC) transporter
CFBP5499_RS04565	COG2852	Protein conserved in bacteria
CFBP5499_RS04575	COG0215	cysteine-tRNA ligase activity
CFBP5499_RS04580	COG4221	oxidoreductase activity
CFBP5499_RS04585	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFBP5499_RS04590	COG1286	toxin biosynthetic process
CFBP5499_RS04610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP5499_RS04620	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CFBP5499_RS04630	COG0305	Participates in initiation and elongation during chromosome replication
CFBP5499_RS04655	COG0359	binds to the 23S rRNA
CFBP5499_RS04665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFBP5499_RS04670	COG0360	Binds together with S18 to 16S ribosomal RNA
CFBP5499_RS04685	COG0667	Aldo Keto reductase
CFBP5499_RS04690	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CFBP5499_RS04700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5499_RS04705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP5499_RS04715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFBP5499_RS04720	COG1561	YicC-like family, N-terminal region
CFBP5499_RS04725	COG0194	GDP metabolic process
CFBP5499_RS04740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFBP5499_RS04745	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP5499_RS04755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CFBP5499_RS04770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP5499_RS04785	COG1716	ATPase activity
CFBP5499_RS04785	COG5001	Diguanylate cyclase
CFBP5499_RS04790	COG0488	(ABC) transporter
CFBP5499_RS04795	COG3706	GGDEF domain
CFBP5499_RS04805	COG0105	UTP biosynthetic process
CFBP5499_RS04825	COG0314	molybdopterin synthase activity
CFBP5499_RS04830	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CFBP5499_RS04835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFBP5499_RS04840	COG0322	excinuclease ABC activity
CFBP5499_RS04845	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS04855	COG0625	glutathione transferase activity
CFBP5499_RS04870	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CFBP5499_RS04875	COG0243	molybdopterin cofactor binding
CFBP5499_RS04900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFBP5499_RS04905	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFBP5499_RS04915	COG0628	permease
CFBP5499_RS04925	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CFBP5499_RS04930	COG0248	Ppx GppA phosphatase
CFBP5499_RS04945	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CFBP5499_RS04955	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFBP5499_RS04960	COG0477	Major facilitator Superfamily
CFBP5499_RS04965	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFBP5499_RS04975	COG4452	Inner membrane protein CreD
CFBP5499_RS04980	COG0659	secondary active sulfate transmembrane transporter activity
CFBP5499_RS04990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP5499_RS04995	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CFBP5499_RS05005	COG0113	porphobilinogen synthase activity
CFBP5499_RS05030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFBP5499_RS05035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFBP5499_RS05040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP5499_RS05040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP5499_RS05050	COG2249	NAD(P)H dehydrogenase (quinone) activity
CFBP5499_RS05055	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_RS05060	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFBP5499_RS05065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFBP5499_RS05070	COG2814	Major facilitator Superfamily
CFBP5499_RS05075	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CFBP5499_RS05095	COG0416	fatty acid biosynthetic process
CFBP5499_RS05100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFBP5499_RS05105	COG0776	regulation of translation
CFBP5499_RS05145	COG0601	transmembrane transport
CFBP5499_RS05150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS05155	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_RS05165	COG0747	negative chemotaxis
CFBP5499_RS05175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFBP5499_RS05180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFBP5499_RS05195	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFBP5499_RS05200	COG0583	DNA-binding transcription factor activity
CFBP5499_RS05205	COG0737	Belongs to the 5'-nucleotidase family
CFBP5499_RS05230	COG2897	thiosulfate sulfurtransferase activity
CFBP5499_RS05245	COG0415	Belongs to the DNA photolyase family
CFBP5499_RS05255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP5499_RS05290	COG3932	Exopolysaccharide synthesis, ExoD
CFBP5499_RS05310	COG4139	cobalamin transport
CFBP5499_RS05315	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFBP5499_RS05320	COG3794	PFAM blue (type 1) copper domain protein
CFBP5499_RS05390	COG1612	heme a metabolic process
CFBP5499_RS05400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFBP5499_RS05405	COG0010	Belongs to the arginase family
CFBP5499_RS05410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFBP5499_RS05415	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFBP5499_RS05430	COG1832	CoA-binding protein
CFBP5499_RS05445	COG2124	cytochrome p450
CFBP5499_RS05450	COG2199	diguanylate cyclase activity
CFBP5499_RS05455	COG0740	serine-type endopeptidase activity
CFBP5499_RS05460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFBP5499_RS05470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFBP5499_RS05480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP5499_RS05505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5499_RS05510	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5499_RS05515	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5499_RS05525	COG0649	NAD binding
CFBP5499_RS05535	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CFBP5499_RS05540	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CFBP5499_RS05550	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CFBP5499_RS05555	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5499_RS05565	COG0713	ATP synthesis coupled electron transport
CFBP5499_RS05580	COG1007	ATP synthesis coupled electron transport
CFBP5499_RS05585	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CFBP5499_RS05585	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CFBP5499_RS05605	COG0442	prolyl-tRNA aminoacylation
CFBP5499_RS05615	COG1136	(ABC) transporter
CFBP5499_RS05635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP5499_RS05655	COG0784	Response regulator, receiver
CFBP5499_RS05670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFBP5499_RS05675	COG0477	Major facilitator Superfamily
CFBP5499_RS05690	COG0557	exoribonuclease II activity
CFBP5499_RS05695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFBP5499_RS05705	COG0758	DNA mediated transformation
CFBP5499_RS05710	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CFBP5499_RS05720	COG0540	Belongs to the ATCase OTCase family
CFBP5499_RS05730	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_RS05735	COG0456	acetyltransferase
CFBP5499_RS05750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFBP5499_RS05755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CFBP5499_RS05760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP5499_RS05765	COG0154	amidase activity
CFBP5499_RS05770	COG3811	Belongs to the UPF0386 family
CFBP5499_RS05785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP5499_RS05795	COG0456	acetyltransferase
CFBP5499_RS05810	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CFBP5499_RS05815	COG0439	Biotin carboxylase
CFBP5499_RS05820	COG0511	ligase activity, forming carbon-carbon bonds
CFBP5499_RS05825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP5499_RS05835	COG0436	Aminotransferase
CFBP5499_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS05860	COG1530	ribonuclease E activity
CFBP5499_RS05875	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP5499_RS05895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFBP5499_RS05900	COG0384	phenazine biosynthesis protein PhzF
CFBP5499_RS05915	COG0633	Ferredoxin
CFBP5499_RS05925	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFBP5499_RS05930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFBP5499_RS05935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFBP5499_RS05945	COG3768	UPF0283 membrane protein
CFBP5499_RS05950	COG3106	COG3106 Predicted ATPase
CFBP5499_RS05980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFBP5499_RS06020	COG0537	adenosine 5'-monophosphoramidase activity
CFBP5499_RS06045	COG0052	Belongs to the universal ribosomal protein uS2 family
CFBP5499_RS06050	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFBP5499_RS06055	COG0528	UMP kinase activity
CFBP5499_RS06060	COG0233	cytoplasmic translational termination
CFBP5499_RS06065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFBP5499_RS06075	COG0750	zinc metalloprotease
CFBP5499_RS06080	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP5499_RS06085	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP5499_RS06090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP5499_RS06095	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP5499_RS06100	COG3494	Protein of unknown function (DUF1009)
CFBP5499_RS06105	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP5499_RS06110	COG2186	Transcriptional regulator
CFBP5499_RS06120	COG0765	amino acid transport
CFBP5499_RS06125	COG0765	amino acid transport
CFBP5499_RS06135	COG0372	Belongs to the citrate synthase family
CFBP5499_RS06150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFBP5499_RS06155	COG4598	ABC transporter
CFBP5499_RS06160	COG0765	amino acid transport
CFBP5499_RS06165	COG0765	amino acid transport
CFBP5499_RS06170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS06175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_RS06185	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS06195	COG2182	Extracellular solute-binding protein
CFBP5499_RS06205	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_RS06210	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS06215	COG1063	alcohol dehydrogenase
CFBP5499_RS06220	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CFBP5499_RS06230	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CFBP5499_RS06235	COG0148	phosphopyruvate hydratase activity
CFBP5499_RS06245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFBP5499_RS06250	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP5499_RS06250	COG0022	dehydrogenase e1 component
CFBP5499_RS06255	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP5499_RS06265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFBP5499_RS06275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFBP5499_RS06280	COG0697	spore germination
CFBP5499_RS06300	COG2867	negative regulation of translational initiation
CFBP5499_RS06305	COG1546	Belongs to the CinA family
CFBP5499_RS06310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFBP5499_RS06310	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFBP5499_RS06320	COG3852	Histidine kinase
CFBP5499_RS06325	COG2204	response regulator
CFBP5499_RS06330	COG5000	phosphorelay sensor kinase activity
CFBP5499_RS06335	COG2204	response regulator
CFBP5499_RS06340	COG0569	domain protein
CFBP5499_RS06345	COG1923	regulation of RNA biosynthetic process
CFBP5499_RS06350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFBP5499_RS06355	COG3956	TIGRFAM MazG family protein
CFBP5499_RS06370	COG1648	precorrin-2 dehydrogenase activity
CFBP5499_RS06370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP5499_RS06410	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP5499_RS06410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP5499_RS06415	COG0509	glycine decarboxylation via glycine cleavage system
CFBP5499_RS06420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP5499_RS06445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFBP5499_RS06450	COG0564	pseudouridine synthase activity
CFBP5499_RS06470	COG0251	oxidation-reduction process
CFBP5499_RS06475	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CFBP5499_RS06485	COG1671	Belongs to the UPF0178 family
CFBP5499_RS06495	COG0450	alkyl hydroperoxide reductase
CFBP5499_RS06565	COG0431	NADPH-dependent FMN reductase
CFBP5499_RS06575	COG0798	PFAM Bile acid sodium symporter
CFBP5499_RS06590	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CFBP5499_RS06590	COG0321	lipoyl(octanoyl) transferase activity
CFBP5499_RS06595	COG0084	hydrolase, TatD family'
CFBP5499_RS06600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP5499_RS06610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFBP5499_RS06655	COG1802	Transcriptional regulator
CFBP5499_RS06655	COG4626	Terminase
CFBP5499_RS06730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP5499_RS06735	COG2095	MarC family integral membrane protein
CFBP5499_RS06745	COG0629	single-stranded DNA binding
CFBP5499_RS06750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFBP5499_RS06765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFBP5499_RS06785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP5499_RS06790	COG1121	(ABC) transporter
CFBP5499_RS06800	COG1609	Transcriptional regulator
CFBP5499_RS06810	COG0667	Aldo Keto reductase
CFBP5499_RS06820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFBP5499_RS06900	COG2239	Acts as a magnesium transporter
CFBP5499_RS06905	COG0243	molybdopterin cofactor binding
CFBP5499_RS06915	COG0242	peptide deformylase activity
CFBP5499_RS06945	COG0321	lipoyl(octanoyl) transferase activity
CFBP5499_RS06950	COG1064	alcohol dehydrogenase
CFBP5499_RS06980	COG1862	Preprotein translocase
CFBP5499_RS06995	COG1309	transcriptional regulator
CFBP5499_RS07000	COG2124	cytochrome p450
CFBP5499_RS07015	COG0596	Alpha beta hydrolase
CFBP5499_RS07025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP5499_RS07030	COG0626	cystathionine gamma-synthase activity
CFBP5499_RS07035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS07040	COG4597	amino acid ABC transporter
CFBP5499_RS07045	COG0765	amino acid transport
CFBP5499_RS07050	COG1126	abc transporter atp-binding protein
CFBP5499_RS07075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFBP5499_RS07090	COG0436	Aminotransferase
CFBP5499_RS07120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP5499_RS07135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP5499_RS07140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5499_RS07145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP5499_RS07160	COG3243	poly(R)-hydroxyalkanoic acid synthase
CFBP5499_RS07165	COG1489	DNA binding
CFBP5499_RS07170	COG0024	Methionine aminopeptidase
CFBP5499_RS07175	COG2003	Belongs to the UPF0758 family
CFBP5499_RS07190	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CFBP5499_RS07205	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFBP5499_RS07210	COG0546	phosphoglycolate phosphatase activity
CFBP5499_RS07220	COG0114	fumarate hydratase activity
CFBP5499_RS07225	COG0504	CTP synthase activity
CFBP5499_RS07235	COG0149	triose-phosphate isomerase activity
CFBP5499_RS07245	COG0187	DNA topoisomerase II activity
CFBP5499_RS07250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFBP5499_RS07255	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS07265	COG3264	Mechanosensitive ion channel
CFBP5499_RS07265	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CFBP5499_RS07330	COG1127	ABC transporter
CFBP5499_RS07335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFBP5499_RS07340	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_RS07350	COG0281	malic enzyme
CFBP5499_RS07350	COG0280	phosphate acetyltransferase
CFBP5499_RS07360	COG0778	Nitroreductase
CFBP5499_RS07365	COG0823	Involved in the tonB-independent uptake of proteins
CFBP5499_RS07380	COG1368	sulfuric ester hydrolase activity
CFBP5499_RS07410	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFBP5499_RS07435	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFBP5499_RS07440	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFBP5499_RS07460	COG0019	diaminopimelate decarboxylase activity
CFBP5499_RS07480	COG0343	queuine tRNA-ribosyltransferase activity
CFBP5499_RS07485	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFBP5499_RS07500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFBP5499_RS07525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFBP5499_RS07530	COG0134	indole-3-glycerol-phosphate synthase activity
CFBP5499_RS07535	COG0315	cyclic pyranopterin monophosphate synthase activity
CFBP5499_RS07540	COG0303	'Molybdopterin
CFBP5499_RS07545	COG3706	GGDEF domain
CFBP5499_RS07555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP5499_RS07555	COG0475	glutathione-regulated potassium exporter activity
CFBP5499_RS07570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFBP5499_RS07575	COG0697	spore germination
CFBP5499_RS07580	COG2814	Major facilitator Superfamily
CFBP5499_RS07585	COG0746	molybdenum cofactor guanylyltransferase activity
CFBP5499_RS07590	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFBP5499_RS07595	COG0739	heme binding
CFBP5499_RS07600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP5499_RS07605	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CFBP5499_RS07610	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP5499_RS07615	COG0805	protein transport
CFBP5499_RS07620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP5499_RS07625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP5499_RS07630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFBP5499_RS07635	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFBP5499_RS07640	COG1472	Belongs to the glycosyl hydrolase 3 family
CFBP5499_RS07650	COG0018	arginyl-trna synthetase
CFBP5499_RS07655	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CFBP5499_RS07660	COG0316	Belongs to the HesB IscA family
CFBP5499_RS07670	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CFBP5499_RS07685	COG0525	valine-tRNA ligase activity
CFBP5499_RS07695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP5499_RS07740	COG0655	NAD(P)H dehydrogenase (quinone) activity
CFBP5499_RS07745	COG1546	Belongs to the CinA family
CFBP5499_RS07745	COG1058	Belongs to the CinA family
CFBP5499_RS07750	COG0589	response to stress
CFBP5499_RS07755	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CFBP5499_RS07760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFBP5499_RS07775	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP5499_RS07785	COG1132	(ABC) transporter
CFBP5499_RS07790	COG0628	permease
CFBP5499_RS07825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFBP5499_RS07835	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFBP5499_RS07845	COG0302	gtp cyclohydrolase
CFBP5499_RS07850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFBP5499_RS07855	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP5499_RS07860	COG0516	GMP reductase activity
CFBP5499_RS07860	COG0517	IMP dehydrogenase activity
CFBP5499_RS07900	COG1760	l-serine dehydratase
CFBP5499_RS07935	COG0583	DNA-binding transcription factor activity
CFBP5499_RS07950	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFBP5499_RS07950	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFBP5499_RS07955	COG0347	Belongs to the P(II) protein family
CFBP5499_RS07960	COG0174	glutamine synthetase
CFBP5499_RS07990	COG0697	spore germination
CFBP5499_RS08005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFBP5499_RS08015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFBP5499_RS08045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP5499_RS08055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFBP5499_RS08060	COG2186	Transcriptional regulator
CFBP5499_RS08070	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS08075	COG4603	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS08080	COG3845	ABC transporter
CFBP5499_RS08085	COG1183	phosphatidylcholine synthase activity
CFBP5499_RS08090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP5499_RS08095	COG0679	Auxin Efflux Carrier
CFBP5499_RS08100	COG0785	Cytochrome C biogenesis protein
CFBP5499_RS08130	COG1278	Cold shock
CFBP5499_RS08190	COG1876	peptidase activity
CFBP5499_RS08290	COG0577	efflux transmembrane transporter activity
CFBP5499_RS08290	COG1136	(ABC) transporter
CFBP5499_RS08295	COG1136	(ABC) transporter
CFBP5499_RS08295	COG0577	efflux transmembrane transporter activity
CFBP5499_RS08310	COG2151	metal-sulfur cluster biosynthetic enzyme
CFBP5499_RS08315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFBP5499_RS08320	COG0719	Fe-S assembly protein
CFBP5499_RS08325	COG0396	ATPase activity
CFBP5499_RS08335	COG0719	Fe-S assembly protein
CFBP5499_RS08340	COG1104	cysteine desulfurase activity
CFBP5499_RS08345	COG2945	thiolester hydrolase activity
CFBP5499_RS08355	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFBP5499_RS08360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFBP5499_RS08370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFBP5499_RS08375	COG0739	heme binding
CFBP5499_RS08380	COG0513	Belongs to the DEAD box helicase family
CFBP5499_RS08420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFBP5499_RS08430	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP5499_RS08435	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP5499_RS08440	COG0047	phosphoribosylformylglycinamidine synthase activity
CFBP5499_RS08455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5499_RS08460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP5499_RS08485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CFBP5499_RS08490	COG2814	Major facilitator Superfamily
CFBP5499_RS08495	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_RS08500	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_RS08505	COG0037	tRNA processing
CFBP5499_RS08510	COG2066	Belongs to the glutaminase family
CFBP5499_RS08515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFBP5499_RS08520	COG0861	Integral membrane protein TerC family
CFBP5499_RS08535	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_RS08550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFBP5499_RS08555	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CFBP5499_RS08565	COG0538	isocitrate dehydrogenase activity
CFBP5499_RS08590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFBP5499_RS08595	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFBP5499_RS08600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_RS08605	COG2313	pseudouridylate synthase activity
CFBP5499_RS08610	COG3385	transposase activity
CFBP5499_RS08625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS08630	COG4215	(ABC) transporter
CFBP5499_RS08640	COG5425	PFAM Usg family protein
CFBP5499_RS08650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_RS08655	COG1522	sequence-specific DNA binding
CFBP5499_RS08660	COG1573	uracil-dna glycosylase
CFBP5499_RS08670	COG2205	protein histidine kinase activity
CFBP5499_RS08670	COG2202	Pas domain
CFBP5499_RS08680	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CFBP5499_RS08685	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CFBP5499_RS08700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP5499_RS08710	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS08715	COG1129	ABC transporter
CFBP5499_RS08725	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS08730	COG3959	Transketolase, thiamine diphosphate binding domain
CFBP5499_RS08735	COG3958	Transketolase
CFBP5499_RS08740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP5499_RS08745	COG2390	Transcriptional regulator
CFBP5499_RS08755	COG0842	Transport permease protein
CFBP5499_RS08760	COG1131	(ABC) transporter
CFBP5499_RS08780	COG0840	transmembrane signaling receptor activity
CFBP5499_RS08780	COG0840	transmembrane signaling receptor activity
CFBP5499_RS08790	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFBP5499_RS08795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP5499_RS08810	COG0129	dihydroxy-acid dehydratase activity
CFBP5499_RS08815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFBP5499_RS08820	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CFBP5499_RS08830	COG0203	ribosomal protein L17
CFBP5499_RS08835	COG0202	RNA polymerase activity
CFBP5499_RS08840	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFBP5499_RS08845	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFBP5499_RS08850	COG0563	adenylate kinase activity
CFBP5499_RS08855	COG0201	protein transport
CFBP5499_RS08860	COG0200	Binds to the 23S rRNA
CFBP5499_RS08865	COG1841	ribosomal large subunit assembly
CFBP5499_RS08870	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFBP5499_RS08875	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFBP5499_RS08880	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFBP5499_RS08885	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFBP5499_RS08890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFBP5499_RS08895	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFBP5499_RS08900	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFBP5499_RS08905	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFBP5499_RS08910	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFBP5499_RS08915	COG0255	Belongs to the universal ribosomal protein uL29 family
CFBP5499_RS08920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFBP5499_RS08925	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFBP5499_RS08930	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFBP5499_RS08935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFBP5499_RS08940	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFBP5499_RS08945	COG0089	rRNA binding
CFBP5499_RS08950	COG0088	Forms part of the polypeptide exit tunnel
CFBP5499_RS08955	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFBP5499_RS08960	COG0051	transcription antitermination factor activity, RNA binding
CFBP5499_RS08965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP5499_RS08970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFBP5499_RS08975	COG0049	tRNA binding
CFBP5499_RS08980	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFBP5499_RS09000	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFBP5499_RS09005	COG0085	RNA polymerase activity
CFBP5499_RS09010	COG0222	ribosome binding
CFBP5499_RS09015	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFBP5499_RS09020	COG0081	regulation of translation
CFBP5499_RS09025	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFBP5499_RS09035	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFBP5499_RS09050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP5499_RS09055	COG0861	Integral membrane protein TerC family
CFBP5499_RS09070	COG3895	Periplasmic Protein
CFBP5499_RS09105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP5499_RS09110	COG1607	acyl-coa hydrolase
CFBP5499_RS09135	COG2910	NAD(P)H-binding
CFBP5499_RS09140	COG1733	regulation of RNA biosynthetic process
CFBP5499_RS09150	COG0556	nucleotide-excision repair
CFBP5499_RS09180	COG0484	heat shock protein binding
CFBP5499_RS09195	COG3706	GGDEF domain
CFBP5499_RS09205	COG3842	ATPase activity
CFBP5499_RS09210	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_RS09215	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_RS09225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5499_RS09240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFBP5499_RS09250	COG2207	Transcriptional regulator
CFBP5499_RS09255	COG1064	alcohol dehydrogenase
CFBP5499_RS09260	COG1252	NADH dehydrogenase
CFBP5499_RS09265	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFBP5499_RS09270	COG2197	response regulator
CFBP5499_RS09275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP5499_RS09280	COG0702	epimerase
CFBP5499_RS09320	COG0656	L-ascorbic acid biosynthetic process
CFBP5499_RS09335	COG0440	acetolactate synthase activity
CFBP5499_RS09340	COG0028	Belongs to the TPP enzyme family
CFBP5499_RS09350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFBP5499_RS09355	COG0560	Phosphoserine phosphatase
CFBP5499_RS09375	COG0330	HflC and HflK could
CFBP5499_RS09380	COG0330	HflC and HflK could
CFBP5499_RS09390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFBP5499_RS09425	COG0277	FAD linked oxidase domain protein
CFBP5499_RS09430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP5499_RS09465	COG0596	Alpha beta hydrolase
CFBP5499_RS09485	COG1335	isochorismatase
CFBP5499_RS09515	COG2264	protein methyltransferase activity
CFBP5499_RS09520	COG1999	signal sequence binding
CFBP5499_RS09530	COG0835	chemotaxis
CFBP5499_RS09545	COG0583	DNA-binding transcription factor activity
CFBP5499_RS09555	COG1247	-acetyltransferase
CFBP5499_RS09565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFBP5499_RS09580	COG0497	DNA recombination
CFBP5499_RS09585	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP5499_RS09595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP5499_RS09600	COG0849	cell division
CFBP5499_RS09605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFBP5499_RS09610	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFBP5499_RS09615	COG0477	Major facilitator Superfamily
CFBP5499_RS09620	COG5001	Diguanylate cyclase
CFBP5499_RS09620	COG3300	MHYT domain
CFBP5499_RS09625	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFBP5499_RS09630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFBP5499_RS09635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFBP5499_RS09645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFBP5499_RS09650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFBP5499_RS09660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFBP5499_RS09675	COG0275	rRNA processing
CFBP5499_RS09680	COG2001	Belongs to the MraZ family
CFBP5499_RS09685	COG0604	alcohol dehydrogenase
CFBP5499_RS09685	COG3321	synthase
CFBP5499_RS09690	COG0300	oxidoreductase activity
CFBP5499_RS09720	COG3023	N-Acetylmuramoyl-L-alanine amidase
CFBP5499_RS09750	COG4106	trans-aconitate 2-methyltransferase activity
CFBP5499_RS09770	COG2226	methyltransferase
CFBP5499_RS09780	COG2267	carboxylic ester hydrolase activity
CFBP5499_RS09785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP5499_RS09800	COG0251	oxidation-reduction process
CFBP5499_RS09815	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_RS09820	COG2814	Major facilitator Superfamily
CFBP5499_RS09825	COG1309	transcriptional regulator
CFBP5499_RS09845	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS09850	COG0174	glutamine synthetase
CFBP5499_RS09855	COG0531	amino acid
CFBP5499_RS09865	COG1737	Transcriptional regulator
CFBP5499_RS09875	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_RS09880	COG1178	ABC-type Fe3 transport system permease component
CFBP5499_RS09890	COG3842	ATPase activity
CFBP5499_RS09950	COG2968	Membrane
CFBP5499_RS09960	COG0432	Pfam Uncharacterised protein family UPF0047
CFBP5499_RS09975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP5499_RS09980	COG0358	DNA primase activity
CFBP5499_RS09990	COG0505	Belongs to the CarA family
CFBP5499_RS09995	COG0534	Mate efflux family protein
CFBP5499_RS10010	COG2321	neutral zinc metallopeptidase
CFBP5499_RS10025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFBP5499_RS10035	COG3706	GGDEF domain
CFBP5499_RS10050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFBP5499_RS10060	COG1522	sequence-specific DNA binding
CFBP5499_RS10065	COG0492	ferredoxin-NADP+ reductase activity
CFBP5499_RS10070	COG0583	DNA-binding transcription factor activity
CFBP5499_RS10080	COG1902	pentaerythritol trinitrate reductase activity
CFBP5499_RS10115	COG0387	Pfam Sodium calcium exchanger
CFBP5499_RS10120	COG0436	Aminotransferase
CFBP5499_RS10125	COG2200	EAL domain
CFBP5499_RS10125	COG2199	diguanylate cyclase activity
CFBP5499_RS10140	COG1278	Cold shock
CFBP5499_RS10145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP5499_RS10160	COG1846	Transcriptional regulator
CFBP5499_RS10165	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS10170	COG2205	protein histidine kinase activity
CFBP5499_RS10175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP5499_RS10195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFBP5499_RS10205	COG1496	oxidoreductase activity
CFBP5499_RS10220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFBP5499_RS10230	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CFBP5499_RS10245	COG0840	transmembrane signaling receptor activity
CFBP5499_RS10250	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS10255	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CFBP5499_RS10260	COG5001	Diguanylate cyclase
CFBP5499_RS10260	COG3300	MHYT domain
CFBP5499_RS10265	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFBP5499_RS10270	COG5001	Diguanylate cyclase
CFBP5499_RS10280	COG0193	aminoacyl-tRNA hydrolase activity
CFBP5499_RS10290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFBP5499_RS10295	COG0012	GTP binding
CFBP5499_RS10310	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFBP5499_RS10320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CFBP5499_RS10320	COG2857	Cytochrome c1
CFBP5499_RS10340	COG1132	(ABC) transporter
CFBP5499_RS10345	COG1132	(ABC) transporter
CFBP5499_RS10350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFBP5499_RS10365	COG0408	coproporphyrinogen oxidase activity
CFBP5499_RS10380	COG0617	tRNA 3'-terminal CCA addition
CFBP5499_RS10395	COG0714	Associated with various cellular activities
CFBP5499_RS10415	COG0454	-acetyltransferase
CFBP5499_RS10420	COG0477	Major facilitator Superfamily
CFBP5499_RS10430	COG0435	Glutathione S-transferase
CFBP5499_RS10445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFBP5499_RS10460	COG3135	benzoate transporter
CFBP5499_RS10470	COG1595	DNA-templated transcription, initiation
CFBP5499_RS10480	COG0740	serine-type endopeptidase activity
CFBP5499_RS10495	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFBP5499_RS10500	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFBP5499_RS10530	COG4175	Glycine betaine
CFBP5499_RS10545	COG1435	thymidine kinase activity
CFBP5499_RS10580	COG0512	Glutamine amidotransferase of anthranilate synthase
CFBP5499_RS10580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFBP5499_RS10595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP5499_RS10610	COG0366	Alpha amylase catalytic
CFBP5499_RS10615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_RS10635	COG1160	GTP binding
CFBP5499_RS10655	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CFBP5499_RS10665	COG0024	Methionine aminopeptidase
CFBP5499_RS10675	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS10685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFBP5499_RS10695	COG0583	DNA-binding transcription factor activity
CFBP5499_RS10710	COG0402	S-adenosylhomocysteine deaminase activity
CFBP5499_RS10720	COG1304	FMN binding
CFBP5499_RS10730	COG1309	transcriptional regulator
CFBP5499_RS10735	COG1686	Belongs to the peptidase S11 family
CFBP5499_RS10745	COG2351	hydroxyisourate hydrolase activity
CFBP5499_RS10750	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CFBP5499_RS10775	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP5499_RS10785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS10785	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFBP5499_RS10790	COG2205	protein histidine kinase activity
CFBP5499_RS10790	COG5002	protein histidine kinase activity
CFBP5499_RS10790	COG0784	Response regulator, receiver
CFBP5499_RS10795	COG0513	Belongs to the DEAD box helicase family
CFBP5499_RS10805	COG2259	Doxx family
CFBP5499_RS10810	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_RS10815	COG0697	spore germination
CFBP5499_RS10820	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP5499_RS10830	COG1305	Transglutaminase-like
CFBP5499_RS10855	COG4214	carbohydrate transport
CFBP5499_RS10860	COG1129	ABC transporter
CFBP5499_RS10865	COG4213	ABC transporter substrate-binding protein
CFBP5499_RS10915	COG0840	transmembrane signaling receptor activity
CFBP5499_RS10920	COG0840	transmembrane signaling receptor activity
CFBP5499_RS10925	COG2814	Major facilitator Superfamily
CFBP5499_RS10940	COG4215	(ABC) transporter
CFBP5499_RS10980	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_RS11015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP5499_RS11020	COG2346	COG2346, Truncated hemoglobins
CFBP5499_RS11040	COG1309	transcriptional regulator
CFBP5499_RS11055	COG0494	nUDIX hydrolase
CFBP5499_RS11070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_RS11075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_RS11100	COG1234	tRNA 3'-trailer cleavage
CFBP5499_RS11105	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFBP5499_RS11110	COG0830	nickel cation binding
CFBP5499_RS11115	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CFBP5499_RS11120	COG3385	transposase activity
CFBP5499_RS11135	COG0804	urea catabolic process
CFBP5499_RS11145	COG3755	Protein conserved in bacteria
CFBP5499_RS11155	COG0832	Belongs to the urease beta subunit family
CFBP5499_RS11160	COG3813	Protein conserved in bacteria
CFBP5499_RS11165	COG0831	urea catabolic process
CFBP5499_RS11170	COG0829	nickel cation binding
CFBP5499_RS11195	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS11210	COG0174	glutamine synthetase
CFBP5499_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS11220	COG0784	Response regulator, receiver
CFBP5499_RS11220	COG2198	Histidine kinase
CFBP5499_RS11220	COG5002	protein histidine kinase activity
CFBP5499_RS11265	COG1218	3'(2'),5'-bisphosphate nucleotidase
CFBP5499_RS11345	COG0564	pseudouridine synthase activity
CFBP5499_RS11355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP5499_RS11370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFBP5499_RS11410	COG0346	lactoylglutathione lyase activity
CFBP5499_RS11420	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFBP5499_RS11430	COG2832	Protein of unknown function (DUF454)
CFBP5499_RS11435	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFBP5499_RS11440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_RS11445	COG4558	Periplasmic binding protein
CFBP5499_RS11455	COG3721	Heme iron utilization protein
CFBP5499_RS11475	COG3657	addiction module killer protein
CFBP5499_RS11485	COG2205	protein histidine kinase activity
CFBP5499_RS11525	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_RS11530	COG4605	iron ion homeostasis
CFBP5499_RS11535	COG4604	ABC transporter, ATP-binding protein
CFBP5499_RS11540	COG0783	Belongs to the Dps family
CFBP5499_RS11560	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_RS11565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_RS11570	COG0583	DNA-binding transcription factor activity
CFBP5499_RS11575	COG0657	acetylesterase activity
CFBP5499_RS11580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_RS11600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFBP5499_RS11605	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CFBP5499_RS11610	COG0288	reversible hydration of carbon dioxide
CFBP5499_RS11620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFBP5499_RS11640	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CFBP5499_RS11645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP5499_RS11650	COG0778	Nitroreductase
CFBP5499_RS11655	COG2267	carboxylic ester hydrolase activity
CFBP5499_RS11660	COG0251	oxidation-reduction process
CFBP5499_RS11665	COG1335	isochorismatase
CFBP5499_RS11670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS11680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_RS11695	COG1175	transmembrane transport
CFBP5499_RS11700	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS11705	COG3842	ATPase activity
CFBP5499_RS11710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_RS11720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP5499_RS11735	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS11740	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_RS11745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS11750	COG0601	transmembrane transport
CFBP5499_RS11770	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFBP5499_RS11770	COG0392	lysyltransferase activity
CFBP5499_RS11805	COG2159	amidohydrolase
CFBP5499_RS11810	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_RS11835	COG0450	alkyl hydroperoxide reductase
CFBP5499_RS11860	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS11870	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP5499_RS11870	COG1902	pentaerythritol trinitrate reductase activity
CFBP5499_RS11880	COG3192	ethanolamine utilization protein
CFBP5499_RS11940	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP5499_RS11950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_RS11955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP5499_RS11965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFBP5499_RS11975	COG1509	lysine 2,3-aminomutase activity
CFBP5499_RS11990	COG0583	DNA-binding transcription factor activity
CFBP5499_RS11995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS12000	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFBP5499_RS12005	COG4149	molybdate abc transporter
CFBP5499_RS12010	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CFBP5499_RS12020	COG3191	aminopeptidase activity
CFBP5499_RS12025	COG2022	thiamine diphosphate biosynthetic process
CFBP5499_RS12040	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFBP5499_RS12045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5499_RS12055	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP5499_RS12080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP5499_RS12080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP5499_RS12105	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_RS12125	COG4166	transmembrane transport
CFBP5499_RS12130	COG0601	transmembrane transport
CFBP5499_RS12135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS12145	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_RS12150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFBP5499_RS12155	COG3142	Participates in the control of copper homeostasis
CFBP5499_RS12160	COG2814	Major facilitator Superfamily
CFBP5499_RS12175	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS12180	COG1737	Transcriptional regulator
CFBP5499_RS12190	COG3842	ATPase activity
CFBP5499_RS12200	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS12205	COG1175	transmembrane transport
CFBP5499_RS12220	COG2188	Transcriptional regulator
CFBP5499_RS12225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP5499_RS12230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFBP5499_RS12235	COG1940	carbohydrate kinase activity
CFBP5499_RS12245	COG0671	phosphoesterase, PA-phosphatase related
CFBP5499_RS12250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFBP5499_RS12255	COG0156	8-amino-7-oxononanoate synthase activity
CFBP5499_RS12265	COG0729	surface antigen
CFBP5499_RS12275	COG0835	chemotaxis
CFBP5499_RS12285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFBP5499_RS12290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFBP5499_RS12295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFBP5499_RS12300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFBP5499_RS12305	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFBP5499_RS12310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFBP5499_RS12325	COG4974	Belongs to the 'phage' integrase family
CFBP5499_RS12350	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_RS12360	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP5499_RS12370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFBP5499_RS12375	COG0045	succinate-CoA ligase (ADP-forming) activity
CFBP5499_RS12380	COG0039	L-malate dehydrogenase activity
CFBP5499_RS12385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFBP5499_RS12420	COG2264	protein methyltransferase activity
CFBP5499_RS12435	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFBP5499_RS12440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFBP5499_RS12445	COG0181	hydroxymethylbilane synthase activity
CFBP5499_RS12470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFBP5499_RS12490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFBP5499_RS12500	COG1217	gtp-binding protein TYPA
CFBP5499_RS12505	COG0339	signal peptide processing
CFBP5499_RS12510	COG1846	Transcriptional regulator
CFBP5499_RS12515	COG2814	Major facilitator Superfamily
CFBP5499_RS12520	COG0137	argininosuccinate synthase activity
CFBP5499_RS12530	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_RS12535	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFBP5499_RS12540	COG4120	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS12550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CFBP5499_RS12565	COG2154	pterin-4-alpha-carbinolamine dehydratase
CFBP5499_RS12570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFBP5499_RS12575	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CFBP5499_RS12585	COG4181	ATPase activity
CFBP5499_RS12595	COG0670	Belongs to the BI1 family
CFBP5499_RS12610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFBP5499_RS12615	COG4133	protoheme IX ABC transporter activity
CFBP5499_RS12625	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP5499_RS12630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP5499_RS12655	COG2917	probably involved in intracellular septation
CFBP5499_RS12660	COG0552	protein localization to endoplasmic reticulum
CFBP5499_RS12665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP5499_RS12670	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFBP5499_RS12685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFBP5499_RS12690	COG0287	Prephenate dehydrogenase
CFBP5499_RS12690	COG1605	Chorismate mutase
CFBP5499_RS12695	COG0228	four-way junction DNA binding
CFBP5499_RS12700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFBP5499_RS12705	COG0336	Belongs to the RNA methyltransferase TrmD family
CFBP5499_RS12715	COG0335	large ribosomal subunit rRNA binding
CFBP5499_RS12725	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_RS12730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_RS12750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFBP5499_RS12765	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFBP5499_RS12785	COG0488	(ABC) transporter
CFBP5499_RS12795	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CFBP5499_RS12805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFBP5499_RS12810	COG0142	geranyltranstransferase activity
CFBP5499_RS12815	COG2885	chlorophyll binding
CFBP5499_RS12820	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFBP5499_RS12825	COG2223	nitrite transmembrane transporter activity
CFBP5499_RS12830	COG1349	DNA-binding transcription factor activity
CFBP5499_RS12835	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFBP5499_RS12840	COG2197	response regulator
CFBP5499_RS12845	COG1132	(ABC) transporter
CFBP5499_RS12855	COG3459	Glycosyltransferase 36 associated
CFBP5499_RS12860	COG1473	amidohydrolase
CFBP5499_RS12870	COG0579	oxidoreductase
CFBP5499_RS12880	COG0129	dihydroxy-acid dehydratase activity
CFBP5499_RS12885	COG2084	Dehydrogenase
CFBP5499_RS12890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5499_RS12895	COG0277	FAD linked oxidase domain protein
CFBP5499_RS12900	COG2186	Transcriptional regulator
CFBP5499_RS12910	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP5499_RS12915	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_RS12920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_RS12925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP5499_RS12940	COG0495	leucyl-tRNA aminoacylation
CFBP5499_RS12955	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFBP5499_RS12975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP5499_RS12980	COG1946	Acyl-CoA thioesterase
CFBP5499_RS12985	COG0347	Belongs to the P(II) protein family
CFBP5499_RS12990	COG0004	ammonium transporteR
CFBP5499_RS12995	COG1674	ftsk spoiiie
CFBP5499_RS13000	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CFBP5499_RS13015	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS13025	COG1329	Transcriptional regulator
CFBP5499_RS13030	COG2902	Dehydrogenase
CFBP5499_RS13035	COG2270	Major facilitator Superfamily
CFBP5499_RS13050	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS13065	COG0494	nUDIX hydrolase
CFBP5499_RS13075	COG0793	Belongs to the peptidase S41A family
CFBP5499_RS13085	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFBP5499_RS13090	COG0799	negative regulation of ribosome biogenesis
CFBP5499_RS13095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFBP5499_RS13100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFBP5499_RS13105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFBP5499_RS13110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFBP5499_RS13125	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFBP5499_RS13130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFBP5499_RS13155	COG0066	3-isopropylmalate dehydratase activity
CFBP5499_RS13160	COG0473	3-isopropylmalate dehydrogenase activity
CFBP5499_RS13165	COG1858	cytochrome C peroxidase
CFBP5499_RS13170	COG1797	cobyrinic acid a,c-diamide synthase activity
CFBP5499_RS13175	COG1648	precorrin-2 dehydrogenase activity
CFBP5499_RS13175	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP5499_RS13180	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CFBP5499_RS13245	COG1492	cobalamin metabolic process
CFBP5499_RS13260	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_RS13265	COG3254	rhamnose metabolic process
CFBP5499_RS13270	COG0246	Mannitol dehydrogenase
CFBP5499_RS13275	COG1063	alcohol dehydrogenase
CFBP5499_RS13295	COG4214	carbohydrate transport
CFBP5499_RS13300	COG1129	ABC transporter
CFBP5499_RS13305	COG2186	Transcriptional regulator
CFBP5499_RS13310	COG2721	sulfolactate sulfo-lyase activity
CFBP5499_RS13315	COG0138	bifunctional purine biosynthesis protein purh
CFBP5499_RS13325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFBP5499_RS13325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFBP5499_RS13330	COG0501	Belongs to the peptidase M48B family
CFBP5499_RS13350	COG0357	Ribosomal RNA small subunit methyltransferase G
CFBP5499_RS13355	COG0445	tRNA wobble uridine modification
CFBP5499_RS13360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFBP5499_RS13365	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFBP5499_RS13370	COG1981	membrane
CFBP5499_RS13375	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFBP5499_RS13385	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CFBP5499_RS13390	COG0424	maF-like protein
CFBP5499_RS13395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP5499_RS13400	COG0237	dephospho-CoA kinase activity
CFBP5499_RS13410	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CFBP5499_RS13415	COG3030	protein affecting phage T7 exclusion by the F plasmid
CFBP5499_RS13450	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFBP5499_RS13465	COG0135	phosphoribosylanthranilate isomerase activity
CFBP5499_RS13470	COG0133	tryptophan synthase activity
CFBP5499_RS13475	COG0159	tryptophan synthase activity
CFBP5499_RS13480	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFBP5499_RS13505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFBP5499_RS13515	COG2205	protein histidine kinase activity
CFBP5499_RS13525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CFBP5499_RS13530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP5499_RS13535	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP5499_RS13535	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFBP5499_RS13540	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFBP5499_RS13545	COG0642	Histidine kinase
CFBP5499_RS13550	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS13555	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CFBP5499_RS13565	COG1652	LysM domain
CFBP5499_RS13570	COG1072	(Pantothenic acid kinase))
CFBP5499_RS13575	COG0140	phosphoribosyl-ATP diphosphatase activity
CFBP5499_RS13580	COG0107	imidazoleglycerol-phosphate synthase activity
CFBP5499_RS13585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFBP5499_RS13590	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFBP5499_RS13600	COG0131	Imidazoleglycerol-phosphate dehydratase
CFBP5499_RS13605	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFBP5499_RS13610	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFBP5499_RS13620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFBP5499_RS13635	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CFBP5499_RS13645	COG1643	Atp-dependent helicase
CFBP5499_RS13690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFBP5499_RS13690	COG1017	nitric oxide dioxygenase activity
CFBP5499_RS13695	COG1126	abc transporter atp-binding protein
CFBP5499_RS13700	COG0765	amino acid transport
CFBP5499_RS13705	COG4597	amino acid ABC transporter
CFBP5499_RS13710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS13715	COG0583	DNA-binding transcription factor activity
CFBP5499_RS13720	COG0514	ATP-dependent DNA helicase (RecQ)
CFBP5499_RS13745	COG1072	(Pantothenic acid kinase))
CFBP5499_RS13755	COG1780	Probably involved in ribonucleotide reductase function
CFBP5499_RS13775	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFBP5499_RS13800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_RS13815	COG1185	polyribonucleotide nucleotidyltransferase activity
CFBP5499_RS13820	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFBP5499_RS13825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFBP5499_RS13830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFBP5499_RS13835	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFBP5499_RS13835	COG3064	Membrane
CFBP5499_RS13850	COG0779	Required for maturation of 30S ribosomal subunits
CFBP5499_RS13855	COG2814	Major facilitator Superfamily
CFBP5499_RS13860	COG2951	lytic endotransglycosylase activity
CFBP5499_RS13865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFBP5499_RS13875	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFBP5499_RS13880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFBP5499_RS13895	COG2816	NAD+ diphosphatase activity
CFBP5499_RS13900	COG0077	Prephenate dehydratase
CFBP5499_RS13900	COG1605	Chorismate mutase
CFBP5499_RS13905	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CFBP5499_RS13910	COG3474	cytochrome
CFBP5499_RS13920	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP5499_RS13925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFBP5499_RS13935	COG1278	Cold shock
CFBP5499_RS13945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP5499_RS13955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP5499_RS13955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP5499_RS13960	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CFBP5499_RS13995	COG2900	Belongs to the SlyX family
CFBP5499_RS14005	COG0484	heat shock protein binding
CFBP5499_RS14010	COG0443	Heat shock 70 kDa protein
CFBP5499_RS14025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP5499_RS14030	COG1744	ABC transporter substrate-binding protein PnrA-like
CFBP5499_RS14035	COG3845	ABC transporter
CFBP5499_RS14040	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS14045	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS14055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFBP5499_RS14060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFBP5499_RS14065	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CFBP5499_RS14075	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFBP5499_RS14080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFBP5499_RS14085	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFBP5499_RS14095	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFBP5499_RS14100	COG1845	cytochrome c oxidase, subunit III
CFBP5499_RS14105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP5499_RS14115	COG0477	Major facilitator Superfamily
CFBP5499_RS14120	COG0067	glutamate synthase
CFBP5499_RS14120	COG0069	glutamate synthase activity
CFBP5499_RS14120	COG0070	glutamate synthase
CFBP5499_RS14125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CFBP5499_RS14140	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP5499_RS14150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP5499_RS14185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_RS14205	COG0848	biopolymer transport protein
CFBP5499_RS14215	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP5499_RS14235	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP5499_RS14240	COG3454	Phosphonate metabolism
CFBP5499_RS14245	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP5499_RS14250	COG3639	organic phosphonate transmembrane transporter activity
CFBP5499_RS14255	COG3639	organic phosphonate transmembrane transporter activity
CFBP5499_RS14265	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFBP5499_RS14275	COG4778	phosphonate C-P lyase system protein PhnL
CFBP5499_RS14280	COG4107	phosphonate C-P lyase system protein PhnK
CFBP5499_RS14285	COG3627	carbon phosphorus lyase activity
CFBP5499_RS14290	COG3626	phosphonate metabolism
CFBP5499_RS14295	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CFBP5499_RS14300	COG3624	Phosphonate C-P lyase system protein PhnG
CFBP5499_RS14305	COG2188	Transcriptional regulator
CFBP5499_RS14310	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFBP5499_RS14315	COG0837	glucose binding
CFBP5499_RS14320	COG1803	Methylglyoxal synthase
CFBP5499_RS14325	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CFBP5499_RS14330	COG4166	transmembrane transport
CFBP5499_RS14335	COG4174	ABC transporter (Permease)
CFBP5499_RS14340	COG4239	(ABC) transporter, permease
CFBP5499_RS14345	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_RS14350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS14355	COG0174	glutamine synthetase
CFBP5499_RS14360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS14365	COG3265	gluconokinase activity
CFBP5499_RS14370	COG1174	glycine betaine transport
CFBP5499_RS14375	COG1125	glycine betaine transport
CFBP5499_RS14380	COG1174	glycine betaine transport
CFBP5499_RS14385	COG1732	Glycine betaine
CFBP5499_RS14395	COG1959	2 iron, 2 sulfur cluster binding
CFBP5499_RS14400	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_RS14415	COG0697	spore germination
CFBP5499_RS14430	COG0791	NLP P60 protein
CFBP5499_RS14440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFBP5499_RS14445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP5499_RS14480	COG4964	Belongs to the GSP D family
CFBP5499_RS14535	COG3422	double-strand break repair
CFBP5499_RS14540	COG3757	hydrolase, family 25
CFBP5499_RS14545	COG0697	spore germination
CFBP5499_RS14550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5499_RS14570	COG0481	GTPase activity
CFBP5499_RS14575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP5499_RS14590	COG1396	sequence-specific DNA binding
CFBP5499_RS14605	COG1917	Cupin 2, conserved barrel domain protein
CFBP5499_RS14605	COG2169	Transcriptional regulator
CFBP5499_RS14610	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP5499_RS14635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFBP5499_RS14640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFBP5499_RS14645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFBP5499_RS14655	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFBP5499_RS14660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP5499_RS14660	COG0072	phenylalanine-tRNA ligase activity
CFBP5499_RS14665	COG0667	Aldo Keto reductase
CFBP5499_RS14685	COG4977	sequence-specific DNA binding
CFBP5499_RS14710	COG1570	exodeoxyribonuclease VII activity
CFBP5499_RS14715	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_RS14725	COG1846	Transcriptional regulator
CFBP5499_RS14730	COG0697	spore germination
CFBP5499_RS14735	COG2309	aminopeptidase activity
CFBP5499_RS14740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFBP5499_RS14745	COG1393	Belongs to the ArsC family
CFBP5499_RS14770	COG0519	Catalyzes the synthesis of GMP from XMP
CFBP5499_RS14770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFBP5499_RS14815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CFBP5499_RS14825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFBP5499_RS14835	COG1968	undecaprenyl-diphosphatase activity
CFBP5499_RS14855	COG0284	orotidine-5'-phosphate decarboxylase activity
CFBP5499_RS14865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFBP5499_RS14875	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFBP5499_RS14880	COG0792	nuclease activity
CFBP5499_RS14885	COG0110	maltose O-acetyltransferase activity
CFBP5499_RS14895	COG1175	transmembrane transport
CFBP5499_RS14900	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS14905	COG3842	ATPase activity
CFBP5499_RS14915	COG0189	ligase activity
CFBP5499_RS14920	COG0606	chelatase, subunit chli
CFBP5499_RS14925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFBP5499_RS14930	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_RS14935	COG0756	dUTP diphosphatase activity
CFBP5499_RS14940	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFBP5499_RS14945	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFBP5499_RS14960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFBP5499_RS14965	COG2226	methyltransferase
CFBP5499_RS14970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFBP5499_RS14975	COG1024	Enoyl-CoA hydratase
CFBP5499_RS14980	COG0268	Binds directly to 16S ribosomal RNA
CFBP5499_RS14990	COG2161	toxin-antitoxin pair type II binding
CFBP5499_RS15000	COG3550	peptidyl-serine autophosphorylation
CFBP5499_RS15005	COG1396	sequence-specific DNA binding
CFBP5499_RS15065	COG1132	(ABC) transporter
CFBP5499_RS15080	COG0583	DNA-binding transcription factor activity
CFBP5499_RS15085	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS15100	COG3842	ATPase activity
CFBP5499_RS15110	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_RS15115	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_RS15135	COG0697	spore germination
CFBP5499_RS15140	COG0583	DNA-binding transcription factor activity
CFBP5499_RS15160	COG0596	Alpha beta hydrolase
CFBP5499_RS15175	COG1764	response to oxidative stress
CFBP5499_RS15185	COG0596	Alpha beta hydrolase
CFBP5499_RS15200	COG0783	Belongs to the Dps family
CFBP5499_RS15205	COG0243	molybdopterin cofactor binding
CFBP5499_RS15215	COG4566	intracellular signal transduction
CFBP5499_RS15230	COG2140	Oxalate decarboxylase
CFBP5499_RS15260	COG1522	sequence-specific DNA binding
CFBP5499_RS15265	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS15270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP5499_RS15275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5499_RS15280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFBP5499_RS15285	COG2423	ornithine cyclodeaminase activity
CFBP5499_RS15290	COG0006	proline dipeptidase activity
CFBP5499_RS15295	COG3608	succinylglutamate desuccinylase aspartoacylase
CFBP5499_RS15300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS15305	COG0765	amino acid transport
CFBP5499_RS15310	COG0765	amino acid transport
CFBP5499_RS15315	COG1126	abc transporter atp-binding protein
CFBP5499_RS15325	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5499_RS15340	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS15345	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS15350	COG1129	ABC transporter
CFBP5499_RS15370	COG3284	Transcriptional regulator
CFBP5499_RS15375	COG1063	alcohol dehydrogenase
CFBP5499_RS15395	COG0110	maltose O-acetyltransferase activity
CFBP5499_RS15405	COG0840	transmembrane signaling receptor activity
CFBP5499_RS15410	COG1049	propionate catabolic process, 2-methylcitrate cycle
CFBP5499_RS15435	COG0488	(ABC) transporter
CFBP5499_RS15440	COG5265	(ABC) transporter
CFBP5499_RS15445	COG3181	Tripartite tricarboxylate transporter family receptor
CFBP5499_RS15450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP5499_RS15475	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP5499_RS15485	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_RS15495	COG0405	Gamma-glutamyltransferase
CFBP5499_RS15500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS15505	COG0601	transmembrane transport
CFBP5499_RS15510	COG0747	negative chemotaxis
CFBP5499_RS15515	COG2186	Transcriptional regulator
CFBP5499_RS15525	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_RS15530	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_RS15535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS15540	COG0601	transmembrane transport
CFBP5499_RS15545	COG0747	negative chemotaxis
CFBP5499_RS15550	COG2186	Transcriptional regulator
CFBP5499_RS15560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_RS15565	COG2223	nitrite transmembrane transporter activity
CFBP5499_RS15575	COG3383	formate dehydrogenase (NAD+) activity
CFBP5499_RS15600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP5499_RS15605	COG1802	Transcriptional regulator
CFBP5499_RS15610	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS15615	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_RS15620	COG0402	S-adenosylhomocysteine deaminase activity
CFBP5499_RS15630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS15635	COG0601	transmembrane transport
CFBP5499_RS15645	COG0402	S-adenosylhomocysteine deaminase activity
CFBP5499_RS15660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_RS15670	COG0765	amino acid transport
CFBP5499_RS15675	COG0765	amino acid transport
CFBP5499_RS15680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS15690	COG1609	Transcriptional regulator
CFBP5499_RS15695	COG3938	Belongs to the proline racemase family
CFBP5499_RS15705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS15715	COG0765	amino acid transport
CFBP5499_RS15730	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP5499_RS15735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_RS15745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP5499_RS15750	COG0784	Response regulator, receiver
CFBP5499_RS15765	COG0842	Transport permease protein
CFBP5499_RS15770	COG0842	Transport permease protein
CFBP5499_RS15770	COG1129	ABC transporter
CFBP5499_RS15775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_RS15780	COG1486	melibiose metabolic process
CFBP5499_RS15785	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_RS15790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS15795	COG0601	transmembrane transport
CFBP5499_RS15800	COG0747	negative chemotaxis
CFBP5499_RS15805	COG1486	melibiose metabolic process
CFBP5499_RS15830	COG1940	carbohydrate kinase activity
CFBP5499_RS15835	COG2182	Extracellular solute-binding protein
CFBP5499_RS15840	COG1175	transmembrane transport
CFBP5499_RS15845	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS15850	COG0165	Argininosuccinate lyase
CFBP5499_RS15855	COG3842	ATPase activity
CFBP5499_RS15860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_RS15865	COG3119	arylsulfatase activity
CFBP5499_RS15875	COG0583	DNA-binding transcription factor activity
CFBP5499_RS15880	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS15895	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CFBP5499_RS15910	COG5002	protein histidine kinase activity
CFBP5499_RS15935	COG1392	Phosphate transport regulator
CFBP5499_RS15940	COG0306	phosphate transporter
CFBP5499_RS15945	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP5499_RS15960	COG4106	trans-aconitate 2-methyltransferase activity
CFBP5499_RS15990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFBP5499_RS16000	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP5499_RS16010	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS16015	COG5001	Diguanylate cyclase
CFBP5499_RS16015	COG3300	MHYT domain
CFBP5499_RS16025	COG0747	negative chemotaxis
CFBP5499_RS16030	COG1312	Catalyzes the dehydration of D-mannonate
CFBP5499_RS16035	COG2186	Transcriptional regulator
CFBP5499_RS16040	COG0601	transmembrane transport
CFBP5499_RS16045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS16050	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_RS16055	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS16060	COG0210	DNA helicase
CFBP5499_RS16065	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFBP5499_RS16075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP5499_RS16140	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFBP5499_RS16145	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFBP5499_RS16150	COG1088	dTDP-glucose 4,6-dehydratase activity
CFBP5499_RS16155	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CFBP5499_RS16160	COG1132	(ABC) transporter
CFBP5499_RS16170	COG0583	DNA-binding transcription factor activity
CFBP5499_RS16175	COG0667	Aldo Keto reductase
CFBP5499_RS16180	COG0385	Bile acid
CFBP5499_RS16200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP5499_RS16230	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFBP5499_RS16245	COG1177	transmembrane transport
CFBP5499_RS16250	COG3842	ATPase activity
CFBP5499_RS16260	COG1846	Transcriptional regulator
CFBP5499_RS16260	COG1940	carbohydrate kinase activity
CFBP5499_RS16270	COG0300	oxidoreductase activity
CFBP5499_RS16275	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_RS16280	COG0584	glycerophosphoryl diester phosphodiesterase
CFBP5499_RS16290	COG4149	molybdate abc transporter
CFBP5499_RS16295	COG3842	ATPase activity
CFBP5499_RS16305	COG1940	carbohydrate kinase activity
CFBP5499_RS16315	COG3712	iron ion homeostasis
CFBP5499_RS16320	COG4774	siderophore transport
CFBP5499_RS16325	COG2814	Major facilitator Superfamily
CFBP5499_RS16345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFBP5499_RS16360	COG1175	transmembrane transport
CFBP5499_RS16365	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS16370	COG1609	Transcriptional regulator
CFBP5499_RS16380	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS16385	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5499_RS16395	COG1609	Transcriptional regulator
CFBP5499_RS16400	COG0183	Belongs to the thiolase family
CFBP5499_RS16405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFBP5499_RS16415	COG1414	Transcriptional regulator
CFBP5499_RS16430	COG0583	DNA-binding transcription factor activity
CFBP5499_RS16440	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFBP5499_RS16445	COG3485	protocatechuate 3,4-dioxygenase
CFBP5499_RS16450	COG3485	protocatechuate 3,4-dioxygenase
CFBP5499_RS16460	COG0765	amino acid transport
CFBP5499_RS16465	COG0765	amino acid transport
CFBP5499_RS16470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS16475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS16480	COG1126	abc transporter atp-binding protein
CFBP5499_RS16485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP5499_RS16490	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP5499_RS16520	COG0747	negative chemotaxis
CFBP5499_RS16530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS16545	COG0683	leucine binding
CFBP5499_RS16560	COG0411	ABC transporter
CFBP5499_RS16575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_RS16580	COG3962	Belongs to the TPP enzyme family
CFBP5499_RS16585	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5499_RS16590	COG3718	enzyme involved in inositol metabolism
CFBP5499_RS16595	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS16600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_RS16610	COG1609	Transcriptional regulator
CFBP5499_RS16615	COG1846	Transcriptional regulator
CFBP5499_RS16625	COG0523	cobalamin synthesis protein
CFBP5499_RS16660	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CFBP5499_RS16680	COG0800	Aldolase
CFBP5499_RS16685	COG2954	triphosphatase activity
CFBP5499_RS16695	COG0747	negative chemotaxis
CFBP5499_RS16700	COG0601	transmembrane transport
CFBP5499_RS16705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS16710	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_RS16715	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS16720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CFBP5499_RS16735	COG0346	lactoylglutathione lyase activity
CFBP5499_RS16745	COG0129	dihydroxy-acid dehydratase activity
CFBP5499_RS16755	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_RS16760	COG1129	ABC transporter
CFBP5499_RS16765	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS16770	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS16775	COG2186	Transcriptional regulator
CFBP5499_RS16790	COG0587	DNA-directed DNA polymerase activity
CFBP5499_RS16820	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS16830	COG3842	ATPase activity
CFBP5499_RS16835	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS16840	COG1175	transmembrane transport
CFBP5499_RS16845	COG1653	transport
CFBP5499_RS16855	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS16870	COG5001	Diguanylate cyclase
CFBP5499_RS16875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS16885	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CFBP5499_RS16890	COG2894	cell division
CFBP5499_RS16895	COG0850	regulation of cytokinetic process
CFBP5499_RS16905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5499_RS16910	COG2186	Transcriptional regulator
CFBP5499_RS16915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_RS16925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_RS16930	COG1063	alcohol dehydrogenase
CFBP5499_RS16935	COG1312	Catalyzes the dehydration of D-mannonate
CFBP5499_RS16950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_RS16955	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP5499_RS16955	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_RS16960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS16975	COG0625	glutathione transferase activity
CFBP5499_RS16985	COG1921	L-seryl-tRNASec selenium transferase activity
CFBP5499_RS17000	COG3964	amidohydrolase
CFBP5499_RS17010	COG0601	transmembrane transport
CFBP5499_RS17015	COG0747	negative chemotaxis
CFBP5499_RS17025	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_RS17065	COG4989	oxidoreductase activity
CFBP5499_RS17075	COG2188	Transcriptional regulator
CFBP5499_RS17080	COG3842	ATPase activity
CFBP5499_RS17085	COG1653	transport
CFBP5499_RS17090	COG1175	transmembrane transport
CFBP5499_RS17095	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS17100	COG1501	Belongs to the glycosyl hydrolase 31 family
CFBP5499_RS17115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_RS17120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_RS17125	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CFBP5499_RS17130	COG0352	thiamine-phosphate diphosphorylase activity
CFBP5499_RS17135	COG0351	phosphomethylpyrimidine kinase
CFBP5499_RS17145	COG1522	sequence-specific DNA binding
CFBP5499_RS17150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP5499_RS17155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS17170	COG2204	response regulator
CFBP5499_RS17175	COG4191	Histidine kinase
CFBP5499_RS17180	COG1301	dicarboxylic acid transport
CFBP5499_RS17190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP5499_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS17205	COG1473	amidohydrolase
CFBP5499_RS17225	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_RS17235	COG2942	2-epimerase
CFBP5499_RS17300	COG3307	-O-antigen
CFBP5499_RS17305	COG1596	polysaccharide export
CFBP5499_RS17310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFBP5499_RS17325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP5499_RS17330	COG2972	Histidine kinase
CFBP5499_RS17330	COG0840	transmembrane signaling receptor activity
CFBP5499_RS17335	COG1388	LysM domain
CFBP5499_RS17335	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS17355	COG2094	Belongs to the DNA glycosylase MPG family
CFBP5499_RS17370	COG1609	Transcriptional regulator
CFBP5499_RS17375	COG1653	transport
CFBP5499_RS17390	COG3842	ATPase activity
CFBP5499_RS17400	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS17405	COG0602	queuosine metabolic process
CFBP5499_RS17410	COG0720	synthase
CFBP5499_RS17415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFBP5499_RS17420	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS17435	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS17440	COG1175	transmembrane transport
CFBP5499_RS17460	COG0583	DNA-binding transcription factor activity
CFBP5499_RS17465	COG0280	phosphate acetyltransferase
CFBP5499_RS17465	COG0281	malic enzyme
CFBP5499_RS17480	COG0765	amino acid transport
CFBP5499_RS17485	COG1126	abc transporter atp-binding protein
CFBP5499_RS17490	COG2079	MmgE PrpD family protein
CFBP5499_RS17495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS17505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS17525	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP5499_RS17530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_RS17535	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP5499_RS17540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFBP5499_RS17545	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS17550	COG1129	ABC transporter
CFBP5499_RS17565	COG1473	amidohydrolase
CFBP5499_RS17570	COG0747	negative chemotaxis
CFBP5499_RS17590	COG0601	transmembrane transport
CFBP5499_RS17595	COG0583	DNA-binding transcription factor activity
CFBP5499_RS17600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_RS17605	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_RS17625	COG1595	DNA-templated transcription, initiation
CFBP5499_RS17630	COG1120	ATPase activity
CFBP5499_RS17635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_RS17650	COG2226	methyltransferase
CFBP5499_RS17660	COG1120	ATPase activity
CFBP5499_RS17665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_RS17685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP5499_RS17695	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS17700	COG0473	3-isopropylmalate dehydrogenase activity
CFBP5499_RS17705	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS17710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS17745	COG0601	transmembrane transport
CFBP5499_RS17750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS17755	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_RS17760	COG1522	sequence-specific DNA binding
CFBP5499_RS17765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS17775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS17780	COG1126	abc transporter atp-binding protein
CFBP5499_RS17790	COG1473	amidohydrolase
CFBP5499_RS17795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS17800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS17805	COG1959	2 iron, 2 sulfur cluster binding
CFBP5499_RS17815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP5499_RS17820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS17845	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_RS17880	COG0667	Aldo Keto reductase
CFBP5499_RS17890	COG0583	DNA-binding transcription factor activity
CFBP5499_RS17895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS17910	COG0747	negative chemotaxis
CFBP5499_RS17915	COG1473	amidohydrolase
CFBP5499_RS17920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS17940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS17960	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS17965	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_RS17975	COG0601	transmembrane transport
CFBP5499_RS17985	COG2186	Transcriptional regulator
CFBP5499_RS18000	COG0300	oxidoreductase activity
CFBP5499_RS18010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP5499_RS18010	COG3453	Protein conserved in bacteria
CFBP5499_RS18015	COG0640	Transcriptional regulator
CFBP5499_RS18025	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFBP5499_RS18040	COG0022	dehydrogenase e1 component
CFBP5499_RS18050	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_RS18055	COG0183	Belongs to the thiolase family
CFBP5499_RS18065	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_RS18070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP5499_RS18085	COG1024	Enoyl-CoA hydratase
CFBP5499_RS18090	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFBP5499_RS18095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CFBP5499_RS18100	COG4952	isomerase
CFBP5499_RS18105	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS18105	COG3347	Dehydrogenase
CFBP5499_RS18110	COG1349	DNA-binding transcription factor activity
CFBP5499_RS18120	COG1129	ABC transporter
CFBP5499_RS18125	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS18135	COG3254	rhamnose metabolic process
CFBP5499_RS18150	COG2264	protein methyltransferase activity
CFBP5499_RS18155	COG5001	Diguanylate cyclase
CFBP5499_RS18175	COG4335	DNA alkylation repair
CFBP5499_RS18180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP5499_RS18185	COG4208	sulfate ABC transporter
CFBP5499_RS18195	COG4150	thiosulfate binding
CFBP5499_RS18215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP5499_RS18225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP5499_RS18235	COG1040	competence protein
CFBP5499_RS18240	COG2226	methyltransferase
CFBP5499_RS18255	COG0494	nUDIX hydrolase
CFBP5499_RS18265	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFBP5499_RS18270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFBP5499_RS18275	COG0653	protein targeting
CFBP5499_RS18280	COG0697	spore germination
CFBP5499_RS18320	COG1312	Catalyzes the dehydration of D-mannonate
CFBP5499_RS18325	COG0246	Mannitol dehydrogenase
CFBP5499_RS18330	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS18345	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS18355	COG1129	ABC transporter
CFBP5499_RS18385	COG2376	Dihydroxyacetone kinase
CFBP5499_RS18390	COG3273	potassium ion transport
CFBP5499_RS18390	COG0471	metal ion transport
CFBP5499_RS18420	COG2244	polysaccharide biosynthetic process
CFBP5499_RS18435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP5499_RS18445	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP5499_RS18445	COG0489	protein tyrosine kinase activity
CFBP5499_RS18465	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_RS18470	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_RS18490	COG2273	Hydrolase Family 16
CFBP5499_RS18490	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CFBP5499_RS18535	COG1396	sequence-specific DNA binding
CFBP5499_RS18545	COG1129	ABC transporter
CFBP5499_RS18550	COG4214	carbohydrate transport
CFBP5499_RS18555	COG4213	ABC transporter substrate-binding protein
CFBP5499_RS18570	COG0346	lactoylglutathione lyase activity
CFBP5499_RS18575	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFBP5499_RS18575	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFBP5499_RS18580	COG4770	biotin carboxylase activity
CFBP5499_RS18590	COG0625	glutathione transferase activity
CFBP5499_RS18595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP5499_RS18600	COG3800	Transcriptional regulator
CFBP5499_RS18600	COG1396	sequence-specific DNA binding
CFBP5499_RS18610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP5499_RS18620	COG0300	oxidoreductase activity
CFBP5499_RS18630	COG2096	Adenosyltransferase
CFBP5499_RS18640	COG2086	electron transfer activity
CFBP5499_RS18650	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP5499_RS18660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFBP5499_RS18665	COG0165	Argininosuccinate lyase
CFBP5499_RS18705	COG2884	Cell division ATP-binding protein ftsE
CFBP5499_RS18725	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CFBP5499_RS18735	COG0287	Prephenate dehydrogenase
CFBP5499_RS18740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP5499_RS18745	COG2226	methyltransferase
CFBP5499_RS18750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP5499_RS18770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFBP5499_RS18775	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFBP5499_RS18810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFBP5499_RS18815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFBP5499_RS18830	COG4974	Belongs to the 'phage' integrase family
CFBP5499_RS18835	COG0825	malonyl-CoA metabolic process
CFBP5499_RS18840	COG3034	peptidoglycan biosynthetic process
CFBP5499_RS18845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFBP5499_RS18845	COG0425	Belongs to the sulfur carrier protein TusA family
CFBP5499_RS18850	COG0523	cobalamin synthesis protein
CFBP5499_RS18855	COG1686	Belongs to the peptidase S11 family
CFBP5499_RS18860	COG1473	amidohydrolase
CFBP5499_RS18865	COG1959	2 iron, 2 sulfur cluster binding
CFBP5499_RS18870	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CFBP5499_RS18880	COG0534	Mate efflux family protein
CFBP5499_RS18915	COG2226	methyltransferase
CFBP5499_RS18970	COG1629	transport
CFBP5499_RS18970	COG4774	siderophore transport
CFBP5499_RS18975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CFBP5499_RS18980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_RS18985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_RS18990	COG1120	ATPase activity
CFBP5499_RS19005	COG4953	penicillin-binding protein 1C
CFBP5499_RS19010	COG2373	Large extracellular alpha-helical protein
CFBP5499_RS19015	COG2835	tetraacyldisaccharide 4'-kinase activity
CFBP5499_RS19025	COG3118	belongs to the thioredoxin family
CFBP5499_RS19040	COG0625	glutathione transferase activity
CFBP5499_RS19195	COG4383	Mu-like prophage protein gp29
CFBP5499_RS19215	COG4397	Mu-like prophage major head subunit gpT
CFBP5499_RS19315	COG0482	sulfurtransferase activity
CFBP5499_RS19330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP5499_RS19345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP5499_RS19350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP5499_RS19355	COG0037	tRNA processing
CFBP5499_RS19365	COG2885	chlorophyll binding
CFBP5499_RS19370	COG0823	Involved in the tonB-independent uptake of proteins
CFBP5499_RS19390	COG0824	Thioesterase
CFBP5499_RS19400	COG0494	nUDIX hydrolase
CFBP5499_RS19415	COG2255	four-way junction helicase activity
CFBP5499_RS19420	COG0632	four-way junction helicase activity
CFBP5499_RS19425	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CFBP5499_RS19430	COG0840	transmembrane signaling receptor activity
CFBP5499_RS19435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS19440	COG0217	transcriptional regulatory protein
CFBP5499_RS19455	COG1692	metallophosphoesterase
CFBP5499_RS19465	COG1253	flavin adenine dinucleotide binding
CFBP5499_RS19505	COG0126	phosphoglycerate kinase activity
CFBP5499_RS19510	COG3588	fructose-bisphosphate aldolase
CFBP5499_RS19530	COG0254	rRNA binding
CFBP5499_RS19535	COG1132	(ABC) transporter
CFBP5499_RS19555	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_RS19585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFBP5499_RS19590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFBP5499_RS19595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFBP5499_RS19600	COG0457	Tetratricopeptide repeat
CFBP5499_RS19605	COG3750	Belongs to the UPF0335 family
CFBP5499_RS19625	COG0469	pyruvate kinase activity
CFBP5499_RS19630	COG3108	Peptidase M15
CFBP5499_RS19635	COG2204	response regulator
CFBP5499_RS19640	COG1164	Oligoendopeptidase f
CFBP5499_RS19645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP5499_RS19650	COG5310	Homospermidine synthase
CFBP5499_RS19660	COG0737	Belongs to the 5'-nucleotidase family
CFBP5499_RS19665	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CFBP5499_RS19670	COG0330	HflC and HflK could
CFBP5499_RS19700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP5499_RS19705	COG2951	lytic endotransglycosylase activity
CFBP5499_RS19720	COG2205	protein histidine kinase activity
CFBP5499_RS19730	COG0070	glutamate synthase
CFBP5499_RS19730	COG0069	glutamate synthase activity
CFBP5499_RS19730	COG0067	glutamate synthase
CFBP5499_RS19745	COG2205	protein histidine kinase activity
CFBP5499_RS19750	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CFBP5499_RS19755	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CFBP5499_RS19760	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CFBP5499_RS19770	COG0252	asparaginase activity
CFBP5499_RS19780	COG1027	Aspartate ammonia-lyase
CFBP5499_RS19785	COG2186	Transcriptional regulator
CFBP5499_RS19805	COG1309	transcriptional regulator
CFBP5499_RS19825	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_RS19830	COG4175	Glycine betaine
CFBP5499_RS19830	COG0517	IMP dehydrogenase activity
CFBP5499_RS19835	COG2986	histidine ammonia-lyase
CFBP5499_RS19840	COG2814	Major facilitator Superfamily
CFBP5499_RS19855	COG1522	sequence-specific DNA binding
CFBP5499_RS19860	COG0583	DNA-binding transcription factor activity
CFBP5499_RS19865	COG0667	Aldo Keto reductase
CFBP5499_RS19875	COG1335	isochorismatase
CFBP5499_RS19880	COG0604	alcohol dehydrogenase
CFBP5499_RS19880	COG3321	synthase
CFBP5499_RS19880	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS19890	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS19895	COG3254	rhamnose metabolic process
CFBP5499_RS19915	COG2721	sulfolactate sulfo-lyase activity
CFBP5499_RS19920	COG1129	ABC transporter
CFBP5499_RS19930	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS19935	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_RS19970	COG0583	DNA-binding transcription factor activity
CFBP5499_RS19990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_RS20000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS20005	COG0601	transmembrane transport
CFBP5499_RS20010	COG0747	negative chemotaxis
CFBP5499_RS20020	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP5499_RS20025	COG1454	alcohol dehydrogenase
CFBP5499_RS20065	COG2307	Protein conserved in bacteria
CFBP5499_RS20065	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP5499_RS20080	COG0488	(ABC) transporter
CFBP5499_RS20085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_RS20090	COG1304	FMN binding
CFBP5499_RS20095	COG1846	Transcriptional regulator
CFBP5499_RS20100	COG0840	transmembrane signaling receptor activity
CFBP5499_RS20105	COG1070	Carbohydrate kinase
CFBP5499_RS20110	COG1830	Aldolase
CFBP5499_RS20115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFBP5499_RS20120	COG0667	Aldo Keto reductase
CFBP5499_RS20135	COG1129	ABC transporter
CFBP5499_RS20140	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_RS20170	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP5499_RS20185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP5499_RS20200	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS20215	COG3842	ATPase activity
CFBP5499_RS20230	COG1648	precorrin-2 dehydrogenase activity
CFBP5499_RS20230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP5499_RS20235	COG0243	molybdopterin cofactor binding
CFBP5499_RS20245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFBP5499_RS20250	COG1116	anion transmembrane transporter activity
CFBP5499_RS20255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_RS20260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_RS20270	COG3707	response regulator
CFBP5499_RS20275	COG1802	Transcriptional regulator
CFBP5499_RS20280	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP5499_RS20285	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP5499_RS20290	COG4336	lyase activity
CFBP5499_RS20295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP5499_RS20300	COG4770	biotin carboxylase activity
CFBP5499_RS20305	COG0366	Alpha amylase catalytic
CFBP5499_RS20315	COG4771	TonB-dependent receptor
CFBP5499_RS20320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFBP5499_RS20340	COG1414	Transcriptional regulator
CFBP5499_RS20345	COG1475	DNA binding
CFBP5499_RS20350	COG1192	Involved in chromosome partitioning
CFBP5499_RS20380	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFBP5499_RS20395	COG2986	histidine ammonia-lyase
CFBP5499_RS20400	COG1228	amidohydrolase
CFBP5499_RS20475	COG2079	MmgE PrpD family protein
CFBP5499_RS20485	COG1126	abc transporter atp-binding protein
CFBP5499_RS20495	COG0165	Argininosuccinate lyase
CFBP5499_RS20505	COG0583	DNA-binding transcription factor activity
CFBP5499_RS20515	COG1609	Transcriptional regulator
CFBP5499_RS20535	COG0747	negative chemotaxis
CFBP5499_RS20540	COG0601	transmembrane transport
CFBP5499_RS20545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS20550	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS20555	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_RS20590	COG0477	Major facilitator Superfamily
CFBP5499_RS20610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_RS20625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFBP5499_RS20630	COG3048	D-serine ammonia-lyase activity
CFBP5499_RS20640	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFBP5499_RS20645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFBP5499_RS20650	COG0583	DNA-binding transcription factor activity
CFBP5499_RS20655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS20660	COG4597	amino acid ABC transporter
CFBP5499_RS20665	COG0765	amino acid transport
CFBP5499_RS20695	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS20710	COG0436	Aminotransferase
CFBP5499_RS20735	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS20740	COG3836	Belongs to the HpcH HpaI aldolase family
CFBP5499_RS20760	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS20765	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS20780	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS20795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5499_RS20800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP5499_RS20820	COG0583	DNA-binding transcription factor activity
CFBP5499_RS20825	COG0346	lactoylglutathione lyase activity
CFBP5499_RS20840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CFBP5499_RS20850	COG2814	Major facilitator Superfamily
CFBP5499_RS20860	COG0583	DNA-binding transcription factor activity
CFBP5499_RS20865	COG0477	Major facilitator Superfamily
CFBP5499_RS20870	COG2205	protein histidine kinase activity
CFBP5499_RS20875	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS20880	COG0671	phosphoesterase, PA-phosphatase related
CFBP5499_RS20930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CFBP5499_RS20940	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CFBP5499_RS20945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP5499_RS20950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFBP5499_RS20980	COG0010	Belongs to the arginase family
CFBP5499_RS20990	COG0697	spore germination
CFBP5499_RS20995	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS21015	COG0477	Major facilitator Superfamily
CFBP5499_RS21020	COG0642	Histidine kinase
CFBP5499_RS21030	COG2194	sulfuric ester hydrolase activity
CFBP5499_RS21040	COG0583	DNA-binding transcription factor activity
CFBP5499_RS21045	COG4774	siderophore transport
CFBP5499_RS21060	COG1120	ATPase activity
CFBP5499_RS21070	COG3474	cytochrome
CFBP5499_RS21075	COG2137	regulation of response to DNA damage stimulus
CFBP5499_RS21080	COG3386	PFAM SMP-30 Gluconolaconase
CFBP5499_RS21090	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS21095	COG1129	ABC transporter
CFBP5499_RS21100	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_RS21110	COG4585	Histidine kinase
CFBP5499_RS21115	COG2197	response regulator
CFBP5499_RS21125	COG2133	pyrroloquinoline quinone binding
CFBP5499_RS21135	COG0500	methyltransferase
CFBP5499_RS21140	COG0564	pseudouridine synthase activity
CFBP5499_RS21155	COG4175	Glycine betaine
CFBP5499_RS21155	COG0517	IMP dehydrogenase activity
CFBP5499_RS21160	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_RS21170	COG4191	Histidine kinase
CFBP5499_RS21170	COG0784	Response regulator, receiver
CFBP5499_RS21175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP5499_RS21180	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP5499_RS21180	COG0489	protein tyrosine kinase activity
CFBP5499_RS21185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP5499_RS21190	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_RS21195	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_RS21200	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_RS21205	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_RS21210	COG2273	Hydrolase Family 16
CFBP5499_RS21215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP5499_RS21220	COG2244	polysaccharide biosynthetic process
CFBP5499_RS21225	COG0463	Glycosyl transferase, family 2
CFBP5499_RS21230	COG2327	Polysaccharide pyruvyl transferase
CFBP5499_RS21235	COG3385	transposase activity
CFBP5499_RS21240	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_RS21260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP5499_RS21270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS21285	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP5499_RS21285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP5499_RS21315	COG0033	Phosphoglucomutase
CFBP5499_RS21320	COG0297	glycogen (starch) synthase activity
CFBP5499_RS21325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CFBP5499_RS21330	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFBP5499_RS21335	COG0058	SHG alpha-glucan phosphorylase activity
CFBP5499_RS21350	COG1794	racemase activity, acting on amino acids and derivatives
CFBP5499_RS21355	COG1522	sequence-specific DNA binding
CFBP5499_RS21365	COG2084	Dehydrogenase
CFBP5499_RS21370	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS21375	COG1063	alcohol dehydrogenase
CFBP5499_RS21385	COG4988	ABC transporter
CFBP5499_RS21390	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CFBP5499_RS21400	COG1294	oxidase, subunit
CFBP5499_RS21430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CFBP5499_RS21435	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFBP5499_RS21465	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CFBP5499_RS21470	COG0539	negative regulation of cytoplasmic translation
CFBP5499_RS21500	COG4221	oxidoreductase activity
CFBP5499_RS21510	COG0006	proline dipeptidase activity
CFBP5499_RS21515	COG0747	negative chemotaxis
CFBP5499_RS21520	COG0601	transmembrane transport
CFBP5499_RS21525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS21530	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_RS21535	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS21690	COG2369	cell adhesion
CFBP5499_RS21755	COG4396	Host-nuclease inhibitor protein Gam
CFBP5499_RS21795	COG1475	DNA binding
CFBP5499_RS21820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS21845	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS21865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP5499_RS21870	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS21890	COG4993	Dehydrogenase
CFBP5499_RS21895	COG3685	Protein conserved in bacteria
CFBP5499_RS21920	COG0693	protein deglycase activity
CFBP5499_RS21945	COG0189	ligase activity
CFBP5499_RS21950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5499_RS21955	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFBP5499_RS21965	COG0583	DNA-binding transcription factor activity
CFBP5499_RS21970	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS21975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_RS21980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_RS21985	COG1116	anion transmembrane transporter activity
CFBP5499_RS22000	COG1522	sequence-specific DNA binding
CFBP5499_RS22015	COG0784	Response regulator, receiver
CFBP5499_RS22025	COG3920	Histidine kinase
CFBP5499_RS22035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFBP5499_RS22050	COG0019	diaminopimelate decarboxylase activity
CFBP5499_RS22060	COG3385	transposase activity
CFBP5499_RS22075	COG0527	aspartate kinase activity
CFBP5499_RS22085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFBP5499_RS22090	COG2890	protein-(glutamine-N5) methyltransferase activity
CFBP5499_RS22100	COG0542	response to heat
CFBP5499_RS22105	COG1196	nuclear chromosome segregation
CFBP5499_RS22105	COG0741	lytic transglycosylase activity
CFBP5499_RS22105	COG0739	heme binding
CFBP5499_RS22160	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP5499_RS22160	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP5499_RS22165	COG4311	Sarcosine oxidase, delta subunit
CFBP5499_RS22170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS22175	COG4977	sequence-specific DNA binding
CFBP5499_RS22185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFBP5499_RS22190	COG2218	PFAM glutamate synthase alpha subunit domain protein
CFBP5499_RS22195	COG0069	glutamate synthase activity
CFBP5499_RS22200	COG0174	glutamine synthetase
CFBP5499_RS22220	COG0765	amino acid transport
CFBP5499_RS22225	COG1126	abc transporter atp-binding protein
CFBP5499_RS22240	COG2267	carboxylic ester hydrolase activity
CFBP5499_RS22250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS22255	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS22275	COG1177	transmembrane transport
CFBP5499_RS22280	COG3842	ATPase activity
CFBP5499_RS22295	COG0778	Nitroreductase
CFBP5499_RS22320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS22335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS22340	COG0747	negative chemotaxis
CFBP5499_RS22345	COG0747	negative chemotaxis
CFBP5499_RS22355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS22365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS22375	COG1129	ABC transporter
CFBP5499_RS22380	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS22385	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS22390	COG1454	alcohol dehydrogenase
CFBP5499_RS22400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFBP5499_RS22435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS22440	COG1126	abc transporter atp-binding protein
CFBP5499_RS22445	COG0765	amino acid transport
CFBP5499_RS22465	COG0583	DNA-binding transcription factor activity
CFBP5499_RS22470	COG0028	Belongs to the TPP enzyme family
CFBP5499_RS22480	COG0534	Mate efflux family protein
CFBP5499_RS22495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP5499_RS22500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP5499_RS22510	COG1566	PFAM secretion protein HlyD family protein
CFBP5499_RS22520	COG0625	glutathione transferase activity
CFBP5499_RS22525	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS22530	COG0596	Alpha beta hydrolase
CFBP5499_RS22535	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS22550	COG2186	Transcriptional regulator
CFBP5499_RS22565	COG1175	transmembrane transport
CFBP5499_RS22570	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS22580	COG3842	ATPase activity
CFBP5499_RS22610	COG0431	NADPH-dependent FMN reductase
CFBP5499_RS22620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS22630	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_RS22635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS22645	COG0747	negative chemotaxis
CFBP5499_RS22660	COG0277	FAD linked oxidase domain protein
CFBP5499_RS22700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP5499_RS22720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP5499_RS22725	COG0431	NADPH-dependent FMN reductase
CFBP5499_RS22730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS22755	COG0410	ABC transporter
CFBP5499_RS22775	COG4211	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS22790	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS22810	COG2072	flavoprotein involved in K transport
CFBP5499_RS22830	COG3842	ATPase activity
CFBP5499_RS22835	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_RS22855	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP5499_RS22880	COG0667	Aldo Keto reductase
CFBP5499_RS22895	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS22900	COG1129	ABC transporter
CFBP5499_RS22905	COG4213	ABC transporter substrate-binding protein
CFBP5499_RS22925	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS22930	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_RS22935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS22940	COG0601	transmembrane transport
CFBP5499_RS22945	COG0747	negative chemotaxis
CFBP5499_RS22965	COG0765	amino acid transport
CFBP5499_RS22970	COG4597	amino acid ABC transporter
CFBP5499_RS22975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS22980	COG1473	amidohydrolase
CFBP5499_RS22985	COG2271	Major facilitator Superfamily
CFBP5499_RS22995	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CFBP5499_RS23010	COG3842	ATPase activity
CFBP5499_RS23015	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS23020	COG1175	transmembrane transport
CFBP5499_RS23030	COG1053	succinate dehydrogenase
CFBP5499_RS23030	COG3976	FMN-binding domain protein
CFBP5499_RS23035	COG1609	Transcriptional regulator
CFBP5499_RS23045	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_RS23050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS23055	COG0601	transmembrane transport
CFBP5499_RS23065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_RS23080	COG2828	Protein conserved in bacteria
CFBP5499_RS23085	COG0583	DNA-binding transcription factor activity
CFBP5499_RS23090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5499_RS23115	COG0583	DNA-binding transcription factor activity
CFBP5499_RS23125	COG0511	ligase activity, forming carbon-carbon bonds
CFBP5499_RS23130	COG0439	Biotin carboxylase
CFBP5499_RS23145	COG1984	allophanate hydrolase subunit 2
CFBP5499_RS23150	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP5499_RS23155	COG0436	Aminotransferase
CFBP5499_RS23165	COG4221	oxidoreductase activity
CFBP5499_RS23170	COG0765	amino acid transport
CFBP5499_RS23175	COG0765	amino acid transport
CFBP5499_RS23180	COG1126	abc transporter atp-binding protein
CFBP5499_RS23185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS23190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP5499_RS23205	COG0583	DNA-binding transcription factor activity
CFBP5499_RS23210	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFBP5499_RS23215	COG0583	DNA-binding transcription factor activity
CFBP5499_RS23220	COG2814	Major facilitator Superfamily
CFBP5499_RS23240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFBP5499_RS23245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP5499_RS23265	COG0047	phosphoribosylformylglycinamidine synthase activity
CFBP5499_RS23270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS23280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP5499_RS23280	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP5499_RS23290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFBP5499_RS23305	COG1309	transcriptional regulator
CFBP5499_RS23320	COG1136	(ABC) transporter
CFBP5499_RS23330	COG1063	alcohol dehydrogenase
CFBP5499_RS23340	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_RS23350	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS23370	COG0477	Major facilitator Superfamily
CFBP5499_RS23380	COG5001	Diguanylate cyclase
CFBP5499_RS23380	COG3300	MHYT domain
CFBP5499_RS23390	COG1253	flavin adenine dinucleotide binding
CFBP5499_RS23405	COG3842	ATPase activity
CFBP5499_RS23410	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS23415	COG1175	transmembrane transport
CFBP5499_RS23420	COG1653	transport
CFBP5499_RS23430	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS23435	COG1609	Transcriptional regulator
CFBP5499_RS23450	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_RS23455	COG1129	ABC transporter
CFBP5499_RS23460	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS23465	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS23470	COG1609	Transcriptional regulator
CFBP5499_RS23480	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS23510	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_RS23515	COG0583	DNA-binding transcription factor activity
CFBP5499_RS23520	COG1609	Transcriptional regulator
CFBP5499_RS23530	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_RS23540	COG3842	ATPase activity
CFBP5499_RS23550	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP5499_RS23565	COG1473	amidohydrolase
CFBP5499_RS23580	COG0747	negative chemotaxis
CFBP5499_RS23585	COG0601	transmembrane transport
CFBP5499_RS23590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS23595	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_RS23600	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS23605	COG0583	DNA-binding transcription factor activity
CFBP5499_RS23610	COG0747	negative chemotaxis
CFBP5499_RS23620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS23625	COG0154	amidase activity
CFBP5499_RS23630	COG0693	protein deglycase activity
CFBP5499_RS23640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS23645	COG0601	transmembrane transport
CFBP5499_RS23655	COG1473	amidohydrolase
CFBP5499_RS23660	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_RS23665	COG2390	Transcriptional regulator
CFBP5499_RS23675	COG1175	transmembrane transport
CFBP5499_RS23680	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS23695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5499_RS23700	COG1069	ribulokinase activity
CFBP5499_RS23725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP5499_RS23745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFBP5499_RS23750	COG1414	Transcriptional regulator
CFBP5499_RS23755	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS23765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP5499_RS23770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP5499_RS23775	COG1121	(ABC) transporter
CFBP5499_RS23780	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFBP5499_RS23795	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFBP5499_RS23805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP5499_RS23810	COG0471	metal ion transport
CFBP5499_RS23810	COG3273	potassium ion transport
CFBP5499_RS23815	COG1253	flavin adenine dinucleotide binding
CFBP5499_RS23820	COG1309	transcriptional regulator
CFBP5499_RS23835	COG1609	Transcriptional regulator
CFBP5499_RS23840	COG1070	Carbohydrate kinase
CFBP5499_RS23850	COG2115	Belongs to the xylose isomerase family
CFBP5499_RS23870	COG3385	transposase activity
CFBP5499_RS23875	COG0778	Nitroreductase
CFBP5499_RS23880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFBP5499_RS23885	COG2011	ABC-type metal ion transport system permease component
CFBP5499_RS23895	COG3300	MHYT domain
CFBP5499_RS23895	COG5001	Diguanylate cyclase
CFBP5499_RS23900	COG1054	Belongs to the UPF0176 family
CFBP5499_RS23910	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP5499_RS23915	COG5001	Diguanylate cyclase
CFBP5499_RS23925	COG3257	ureidoglycine aminohydrolase activity
CFBP5499_RS23935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_RS23940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP5499_RS23950	COG1129	ABC transporter
CFBP5499_RS23955	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS23960	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_RS23965	COG0583	DNA-binding transcription factor activity
CFBP5499_RS23980	COG3385	transposase activity
CFBP5499_RS24015	COG0745	RESPONSE REGULATOR receiver
CFBP5499_RS24020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFBP5499_RS24020	COG0784	Response regulator, receiver
CFBP5499_RS24055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP5499_RS24075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP5499_RS24080	COG1473	amidohydrolase
CFBP5499_RS24135	COG1126	abc transporter atp-binding protein
CFBP5499_RS24140	COG0765	amino acid transport
CFBP5499_RS24145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_RS24175	COG3210	domain, Protein
CFBP5499_RS24175	COG3210	domain, Protein
CFBP5499_RS24180	COG2831	hemolysin activation secretion protein
CFBP5499_RS24215	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CFBP5499_RS24235	COG3047	cAMP biosynthetic process
CFBP5499_RS24245	COG3842	ATPase activity
CFBP5499_RS24250	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS24255	COG1175	transmembrane transport
CFBP5499_RS24260	COG1653	transport
CFBP5499_RS24265	COG0523	cobalamin synthesis protein
CFBP5499_RS24280	COG0523	cobalamin synthesis protein
CFBP5499_RS24285	COG1121	(ABC) transporter
CFBP5499_RS24295	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFBP5499_RS24300	COG0328	RNA-DNA hybrid ribonuclease activity
CFBP5499_RS24310	COG0626	cystathionine gamma-synthase activity
CFBP5499_RS24315	COG2182	Extracellular solute-binding protein
CFBP5499_RS24320	COG1175	transmembrane transport
CFBP5499_RS24325	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS24335	COG1609	Transcriptional regulator
CFBP5499_RS24350	COG2084	Dehydrogenase
CFBP5499_RS24355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_RS24365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_RS24370	COG0583	DNA-binding transcription factor activity
CFBP5499_RS24375	COG2223	nitrite transmembrane transporter activity
CFBP5499_RS24410	COG0667	Aldo Keto reductase
CFBP5499_RS24425	COG2186	Transcriptional regulator
CFBP5499_RS24430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5499_RS24435	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CFBP5499_RS24440	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS24445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_RS24450	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_RS24455	COG3618	amidohydrolase
CFBP5499_RS24460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_RS24480	COG1175	transmembrane transport
CFBP5499_RS24485	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS24490	COG3842	ATPase activity
CFBP5499_RS24505	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFBP5499_RS24525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP5499_RS24535	COG1278	Cold shock
CFBP5499_RS24545	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS24560	COG0673	inositol 2-dehydrogenase activity
CFBP5499_RS24565	COG1309	transcriptional regulator
CFBP5499_RS24570	COG1653	transport
CFBP5499_RS24575	COG1175	transmembrane transport
CFBP5499_RS24580	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS24585	COG3842	ATPase activity
CFBP5499_RS24600	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5499_RS24605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_RS24615	COG1609	Transcriptional regulator
CFBP5499_RS24645	COG1175	transmembrane transport
CFBP5499_RS24650	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS24680	COG3842	ATPase activity
CFBP5499_RS24690	COG3385	transposase activity
CFBP5499_RS24695	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_RS24700	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS24710	COG1595	DNA-templated transcription, initiation
CFBP5499_RS24750	COG2233	PERMEase
CFBP5499_RS24765	COG1309	transcriptional regulator
CFBP5499_RS24770	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS24800	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CFBP5499_RS24805	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS24820	COG1609	Transcriptional regulator
CFBP5499_RS24835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS24840	COG0601	transmembrane transport
CFBP5499_RS24845	COG0747	negative chemotaxis
CFBP5499_RS24855	COG0583	DNA-binding transcription factor activity
CFBP5499_RS24865	COG4178	(ABC) transporter
CFBP5499_RS24870	COG1446	asparaginase
CFBP5499_RS24885	COG0747	negative chemotaxis
CFBP5499_RS24905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS24910	COG0601	transmembrane transport
CFBP5499_RS24915	COG2197	response regulator
CFBP5499_RS24940	COG1850	ribulose-bisphosphate carboxylase activity
CFBP5499_RS24950	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS24960	COG2207	Transcriptional regulator
CFBP5499_RS24980	COG0765	amino acid transport
CFBP5499_RS24985	COG1126	abc transporter atp-binding protein
CFBP5499_RS24990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP5499_RS24995	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_RS25000	COG0006	proline dipeptidase activity
CFBP5499_RS25005	COG0504	CTP synthase activity
CFBP5499_RS25035	COG1309	transcriptional regulator
CFBP5499_RS25050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5499_RS25070	COG1309	transcriptional regulator
CFBP5499_RS25075	COG4221	oxidoreductase activity
CFBP5499_RS25080	COG0604	alcohol dehydrogenase
CFBP5499_RS25100	COG1278	Cold shock
CFBP5499_RS25105	COG1696	Membrane protein involved in D-alanine export
CFBP5499_RS25165	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFBP5499_RS25175	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_RS25180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_RS25200	COG4302	ethanolamine ammonia-lyase activity
CFBP5499_RS25225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP5499_RS25230	COG1349	DNA-binding transcription factor activity
CFBP5499_RS25235	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS25245	COG0601	transmembrane transport
CFBP5499_RS25250	COG0747	negative chemotaxis
CFBP5499_RS25290	COG2994	toxin metabolic process
CFBP5499_RS25305	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_RS25310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_RS25315	COG1802	Transcriptional regulator
CFBP5499_RS25365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP5499_RS25425	COG1396	sequence-specific DNA binding
CFBP5499_RS25490	COG1475	DNA binding
CFBP5499_RS25495	COG0640	Transcriptional regulator
CFBP5499_RS25510	COG1126	abc transporter atp-binding protein
CFBP5499_RS25520	COG1609	Transcriptional regulator
CFBP5499_RS25555	COG0640	Transcriptional regulator
CFBP5499_RS25570	COG0798	PFAM Bile acid sodium symporter
CFBP5499_RS25580	COG0431	NADPH-dependent FMN reductase
CFBP5499_RS25590	COG0730	response to heat
CFBP5499_RS25630	COG0210	DNA helicase
CFBP5499_RS25680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_RS25690	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_RS25705	COG2197	response regulator
CFBP5499_RS25715	COG1396	sequence-specific DNA binding
CFBP5499_RS25775	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS25780	COG1733	regulation of RNA biosynthetic process
CFBP5499_RS25790	COG0477	Major facilitator Superfamily
CFBP5499_RS25800	COG1794	racemase activity, acting on amino acids and derivatives
CFBP5499_RS25810	COG0300	oxidoreductase activity
CFBP5499_RS25825	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CFBP5499_RS25830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFBP5499_RS25840	COG1605	Chorismate mutase
CFBP5499_RS25840	COG0287	Prephenate dehydrogenase
CFBP5499_RS25845	COG0583	DNA-binding transcription factor activity
CFBP5499_RS25850	COG0300	oxidoreductase activity
CFBP5499_RS25865	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_RS25875	COG0251	oxidation-reduction process
CFBP5499_RS25940	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP5499_RS25990	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_RS26010	COG0747	negative chemotaxis
CFBP5499_RS26015	COG0601	transmembrane transport
CFBP5499_RS26020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS26025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS26035	COG5001	Diguanylate cyclase
CFBP5499_RS26035	COG3300	MHYT domain
CFBP5499_RS26040	COG3177	Filamentation induced by cAMP protein fic
CFBP5499_RS26045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP5499_RS26060	COG3920	Histidine kinase
CFBP5499_RS26075	COG4095	Psort location CytoplasmicMembrane, score
CFBP5499_RS26085	COG4221	oxidoreductase activity
CFBP5499_RS26110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFBP5499_RS26160	COG1414	Transcriptional regulator
CFBP5499_RS26170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_RS26185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_RS26190	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS26195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS26205	COG4175	Glycine betaine
CFBP5499_RS26205	COG3448	diguanylate cyclase activity
CFBP5499_RS26210	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_RS26215	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_RS26220	COG3938	Belongs to the proline racemase family
CFBP5499_RS26225	COG3177	Filamentation induced by cAMP protein fic
CFBP5499_RS26240	COG3177	Filamentation induced by cAMP protein fic
CFBP5499_RS26245	COG1487	ribonuclease activity
CFBP5499_RS26255	COG4691	Plasmid stability protein
CFBP5499_RS26260	COG1487	ribonuclease activity
CFBP5499_RS26265	COG4191	Histidine kinase
CFBP5499_RS26265	COG0784	Response regulator, receiver
CFBP5499_RS26275	COG1278	Cold shock
CFBP5499_RS26295	COG1609	Transcriptional regulator
CFBP5499_RS26300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_RS26305	COG0477	Major facilitator Superfamily
CFBP5499_RS26315	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS26375	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS26405	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS26415	COG0583	DNA-binding transcription factor activity
CFBP5499_RS26425	COG0297	glycogen (starch) synthase activity
CFBP5499_RS26440	COG0577	efflux transmembrane transporter activity
CFBP5499_RS26485	COG4166	transmembrane transport
CFBP5499_RS26490	COG0601	transmembrane transport
CFBP5499_RS26495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS26500	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_RS26505	COG2843	Capsule synthesis protein
CFBP5499_RS26510	COG2195	Cleaves the N-terminal amino acid of tripeptides
CFBP5499_RS26525	COG4962	Type ii secretion system protein e
CFBP5499_RS26540	COG3451	type IV secretory pathway VirB4
CFBP5499_RS26545	COG5314	conjugation
CFBP5499_RS26555	COG3846	protein secretion by the type IV secretion system
CFBP5499_RS26560	COG3701	Conjugal transfer protein
CFBP5499_RS26580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5499_RS26600	COG1309	transcriptional regulator
CFBP5499_RS26605	COG0667	Aldo Keto reductase
CFBP5499_RS26625	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFBP5499_RS26630	COG2068	MobA-Related Protein
CFBP5499_RS26645	COG1902	pentaerythritol trinitrate reductase activity
CFBP5499_RS26655	COG0604	alcohol dehydrogenase
CFBP5499_RS26660	COG1309	transcriptional regulator
CFBP5499_RS26675	COG0840	transmembrane signaling receptor activity
CFBP5499_RS26705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_RS26710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP5499_RS26720	COG0667	Aldo Keto reductase
CFBP5499_RS26730	COG3833	ABC-type maltose transport systems, permease component
CFBP5499_RS26735	COG1175	transmembrane transport
CFBP5499_RS26740	COG3842	ATPase activity
CFBP5499_RS26745	COG1414	Transcriptional regulator
CFBP5499_RS26765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP5499_RS26775	COG1414	Transcriptional regulator
CFBP5499_RS26780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_RS26810	COG2801	Transposase and inactivated derivatives
CFBP5499_RS26825	COG2252	PERMEase
CFBP5499_RS26830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP5499_RS26920	COG5489	Protein of unknown function (DUF736)
CFBP5499_RS26945	COG1733	regulation of RNA biosynthetic process
CFBP5499_RS26955	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS26975	COG1064	alcohol dehydrogenase
CFBP5499_RS27010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS27025	COG4149	molybdate abc transporter
CFBP5499_RS27045	COG3842	ATPase activity
CFBP5499_RS27050	COG1609	Transcriptional regulator
CFBP5499_RS27060	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS27065	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_RS27075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS27080	COG0601	transmembrane transport
CFBP5499_RS27095	COG0747	negative chemotaxis
CFBP5499_RS27130	COG3005	denitrification pathway
CFBP5499_RS27140	COG0243	molybdopterin cofactor binding
CFBP5499_RS27155	COG4459	periplasmic nitrate reductase
CFBP5499_RS27195	COG0826	peptidase U32
CFBP5499_RS27205	COG3189	MarR family transcriptional regulator
CFBP5499_RS27210	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CFBP5499_RS27230	COG1845	cytochrome c oxidase, subunit III
CFBP5499_RS27245	COG3256	nitric oxide reductase
CFBP5499_RS27250	COG0714	Associated with various cellular activities
CFBP5499_RS27315	COG0300	oxidoreductase activity
CFBP5499_RS27345	COG4208	sulfate ABC transporter
CFBP5499_RS27360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS27370	COG3842	ATPase activity
CFBP5499_RS27375	COG0583	DNA-binding transcription factor activity
CFBP5499_RS27395	COG1309	transcriptional regulator
CFBP5499_RS27440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_RS27440	COG1116	anion transmembrane transporter activity
CFBP5499_RS27445	COG3665	Urea carboxylase-associated protein
CFBP5499_RS27470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFBP5499_RS27475	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS27485	COG3842	ATPase activity
CFBP5499_RS27490	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_RS27495	COG1177	transmembrane transport
CFBP5499_RS27560	COG3177	Filamentation induced by cAMP protein fic
CFBP5499_RS27565	COG2010	Cytochrome c
CFBP5499_RS27565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFBP5499_RS27570	COG2080	2 iron, 2 sulfur cluster binding
CFBP5499_RS27575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP5499_RS27580	COG0596	Alpha beta hydrolase
CFBP5499_RS27585	COG3473	Maleate cis-trans isomerase
CFBP5499_RS27590	COG1335	isochorismatase
CFBP5499_RS27595	COG2309	aminopeptidase activity
CFBP5499_RS27600	COG0477	Major facilitator Superfamily
CFBP5499_RS27605	COG1846	Transcriptional regulator
CFBP5499_RS27615	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFBP5499_RS27615	COG3608	succinylglutamate desuccinylase aspartoacylase
CFBP5499_RS27630	COG1177	transmembrane transport
CFBP5499_RS27635	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_RS27640	COG3842	ATPase activity
CFBP5499_RS27650	COG1609	Transcriptional regulator
CFBP5499_RS27655	COG1192	Involved in chromosome partitioning
CFBP5499_RS27660	COG1475	DNA binding
CFBP5499_RS27665	COG0640	Transcriptional regulator
CFBP5499_RS27695	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFBP5499_RS27710	COG1175	transmembrane transport
CFBP5499_RS27715	COG0395	ABC-type sugar transport system, permease component
CFBP5499_RS27735	COG2972	Histidine kinase
CFBP5499_RS27735	COG0840	transmembrane signaling receptor activity
CFBP5499_RS27745	COG1695	Transcriptional regulator
CFBP5499_RS27755	COG0730	response to heat
CFBP5499_RS27760	COG0659	secondary active sulfate transmembrane transporter activity
CFBP5499_RS27770	COG0431	NADPH-dependent FMN reductase
CFBP5499_RS27780	COG0798	PFAM Bile acid sodium symporter
CFBP5499_RS27790	COG0640	Transcriptional regulator
CFBP5499_RS27810	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFBP5499_RS27815	COG0038	chloride channel
CFBP5499_RS27820	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFBP5499_RS27870	COG0515	serine threonine protein kinase
CFBP5499_RS27925	COG0587	DNA-directed DNA polymerase activity
CFBP5499_RS27955	COG3831	ATPase activity
CFBP5499_RS28010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5499_RS28025	COG1309	transcriptional regulator
CFBP5499_RS28030	COG1802	Transcriptional regulator
CFBP5499_RS28040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_RS28045	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_RS28050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS28060	COG4175	Glycine betaine
CFBP5499_RS28060	COG3448	diguanylate cyclase activity
CFBP5499_RS28065	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_RS28070	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_RS28075	COG3938	Belongs to the proline racemase family
CFBP5499_RS28085	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP5499_RS28090	COG2252	PERMEase
CFBP5499_RS28115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_RS28125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP5499_RS28135	COG0534	Mate efflux family protein
CFBP5499_RS28165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_RS28170	COG1116	anion transmembrane transporter activity
CFBP5499_RS28170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_RS28175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS28185	COG2897	thiosulfate sulfurtransferase activity
CFBP5499_RS28190	COG2963	transposase activity
CFBP5499_RS28195	COG3618	amidohydrolase
CFBP5499_RS28200	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_RS28205	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_RS28210	COG1129	ABC transporter
CFBP5499_RS28215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_RS28220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_RS28225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_RS28230	COG3958	Transketolase
CFBP5499_RS28235	COG3959	Transketolase, thiamine diphosphate binding domain
CFBP5499_RS28240	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_RS28245	COG0583	DNA-binding transcription factor activity
CFBP5499_RS28265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_RS28270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_RS28270	COG1116	anion transmembrane transporter activity
CFBP5499_RS28275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_RS28310	COG0300	oxidoreductase activity
CFBP5499_RS28340	COG3701	Conjugal transfer protein
CFBP5499_RS28345	COG3846	protein secretion by the type IV secretion system
CFBP5499_RS28355	COG5314	conjugation
CFBP5499_RS28360	COG3451	type IV secretory pathway VirB4
CFBP5499_RS28375	COG4962	Type ii secretion system protein e
CFBP5499_RS28405	COG4227	nucleotidyltransferase activity
CFBP5499_RS28410	COG2184	nucleotidyltransferase activity
CFBP5499_RS28610	COG0784	Response regulator, receiver
CFBP5499_RS28625	COG2135	peptidase activity
CFBP5499_RS28650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_RS28655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_RS28660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFBP5499_RS28670	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CFBP5499_RS28675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_RS28720	COG0741	lytic transglycosylase activity
CFBP5499_RS28725	COG3838	Conjugal transfer protein Trbc
CFBP5499_RS28735	COG3451	type IV secretory pathway VirB4
CFBP5499_RS28740	COG0741	lytic transglycosylase activity
CFBP5499_RS28770	COG2948	multi-organism process
CFBP5499_RS28775	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CFBP5499_RS28805	COG1192	Involved in chromosome partitioning
CFBP5499_RS28810	COG1475	DNA binding
CFBP5499_RS28815	COG0640	Transcriptional regulator
CFBP5499_RS28820	COG1192	Involved in chromosome partitioning
CFBP5499_RS28825	COG1475	DNA binding
CFBP5499_RS28830	COG0640	Transcriptional regulator
CFBP5499_RS28920	COG3932	Exopolysaccharide synthesis, ExoD
CFBP5499_RS28930	COG1404	Belongs to the peptidase S8 family
CFBP5499_RS28940	COG1404	Belongs to the peptidase S8 family
CFBP5499_RS29015	COG3436	PFAM IS66 Orf2 family protein
CFBP5499_RS29160	COG1902	pentaerythritol trinitrate reductase activity
CFBP5499_RS29165	COG3321	synthase
CFBP5499_RS29165	COG0604	alcohol dehydrogenase
CFBP5499_RS29175	COG0667	Aldo Keto reductase
CFBP5499_RS29205	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFBP5499_RS29210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFBP5499_RS29275	COG1278	Cold shock
CFBP5499_RS29320	COG1475	DNA binding
CFBP5499_RS29345	COG1396	sequence-specific DNA binding
CFBP5499_RS29365	COG5489	Protein of unknown function (DUF736)
CFBP5499_RS29375	COG0776	regulation of translation
CFBP5499_RS29380	COG3831	ATPase activity
CFBP5499_RS29475	COG1283	sodium-dependent phosphate transmembrane transporter activity
CFBP5499_RS29490	COG0747	negative chemotaxis
CFBP5499_RS29500	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_RS29510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS29515	COG0584	glycerophosphoryl diester phosphodiesterase
CFBP5499_RS29635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_RS29650	COG0747	negative chemotaxis
CFBP5499_RS29675	COG2222	sugar isomerase
CFBP5499_RS29695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_RS29700	COG2222	sugar isomerase
CFBP5499_RS29715	COG3842	ATPase activity
CFBP5499_RS29725	COG2188	Transcriptional regulator
CFBP5499_RS29730	COG0300	oxidoreductase activity
CFBP5499_RS29735	COG0129	dihydroxy-acid dehydratase activity
CFBP5499_RS29745	COG1464	Belongs to the NlpA lipoprotein family
CFBP5499_RS29755	COG2011	ABC-type metal ion transport system permease component
CFBP5499_RS29780	COG3701	Conjugal transfer protein
CFBP5499_RS29785	COG3846	protein secretion by the type IV secretion system
CFBP5499_RS29795	COG5314	conjugation
CFBP5499_RS29800	COG3451	type IV secretory pathway VirB4
CFBP5499_RS29815	COG4962	Type ii secretion system protein e