locus-tag	class	description
CFBP6623_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFBP6623_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP6623_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFBP6623_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFBP6623_RS00025	COG1420	regulation of RNA biosynthetic process
CFBP6623_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFBP6623_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP6623_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFBP6623_RS00050	COG1137	ATPase activity
CFBP6623_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CFBP6623_RS00065	COG0616	signal peptide processing
CFBP6623_RS00070	COG0776	regulation of translation
CFBP6623_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP6623_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFBP6623_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFBP6623_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFBP6623_RS00115	COG0728	peptidoglycan biosynthetic process
CFBP6623_RS00125	COG0180	Tryptophanyl-tRNA synthetase
CFBP6623_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CFBP6623_RS00140	COG1214	PFAM Peptidase M22, glycoprotease
CFBP6623_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP6623_RS00165	COG1702	phosphate starvation-inducible protein PhoH
CFBP6623_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFBP6623_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CFBP6623_RS00185	COG1396	sequence-specific DNA binding
CFBP6623_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFBP6623_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFBP6623_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6623_RS00210	COG0242	peptide deformylase activity
CFBP6623_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFBP6623_RS00220	COG0101	tRNA pseudouridine synthase activity
CFBP6623_RS00225	COG1393	Belongs to the ArsC family
CFBP6623_RS00235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP6623_RS00240	COG2171	N-acyltransferase activity
CFBP6623_RS00250	COG0840	transmembrane signaling receptor activity
CFBP6623_RS00260	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6623_RS00285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFBP6623_RS00300	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CFBP6623_RS00305	COG0706	membrane insertase activity
CFBP6623_RS00310	COG0594	ribonuclease P activity
CFBP6623_RS00315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFBP6623_RS00320	COG0840	transmembrane signaling receptor activity
CFBP6623_RS00340	COG3842	ATPase activity
CFBP6623_RS00345	COG1175	transmembrane transport
CFBP6623_RS00350	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS00365	COG0427	acetyl-CoA hydrolase
CFBP6623_RS00375	COG3938	Belongs to the proline racemase family
CFBP6623_RS00380	COG0418	dihydroorotase activity
CFBP6623_RS00385	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFBP6623_RS00410	COG0166	Belongs to the GPI family
CFBP6623_RS00415	COG0318	PFAM AMP-dependent synthetase and ligase
CFBP6623_RS00420	COG3842	ATPase activity
CFBP6623_RS00425	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6623_RS00430	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP6623_RS00435	COG4774	siderophore transport
CFBP6623_RS00470	COG0582	viral genome integration into host DNA
CFBP6623_RS00485	COG3657	addiction module killer protein
CFBP6623_RS00490	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP6623_RS00525	COG2326	polyphosphate kinase activity
CFBP6623_RS00530	COG5002	protein histidine kinase activity
CFBP6623_RS00535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFBP6623_RS00540	COG0573	inorganic phosphate transmembrane transporter activity
CFBP6623_RS00550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFBP6623_RS00555	COG0704	Plays a role in the regulation of phosphate uptake
CFBP6623_RS00560	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS00575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFBP6623_RS00580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFBP6623_RS00590	COG2967	ApaG domain
CFBP6623_RS00600	COG0717	Belongs to the dCTP deaminase family
CFBP6623_RS00645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFBP6623_RS00695	COG0167	dihydroorotate dehydrogenase activity
CFBP6623_RS00710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP6623_RS00730	COG1959	2 iron, 2 sulfur cluster binding
CFBP6623_RS00735	COG1201	RNA secondary structure unwinding
CFBP6623_RS00770	COG1960	acyl-CoA dehydrogenase activity
CFBP6623_RS00775	COG0183	Belongs to the thiolase family
CFBP6623_RS00780	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP6623_RS00780	COG1024	Enoyl-CoA hydratase
CFBP6623_RS00880	COG1320	monovalent cation:proton antiporter activity
CFBP6623_RS00885	COG2212	antiporter activity
CFBP6623_RS00890	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP6623_RS00895	COG0651	ATP synthesis coupled electron transport
CFBP6623_RS00900	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP6623_RS00905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFBP6623_RS00905	COG2111	Na H antiporter
CFBP6623_RS00915	COG0840	transmembrane signaling receptor activity
CFBP6623_RS00925	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS00930	COG2198	Histidine kinase
CFBP6623_RS00930	COG0643	Histidine kinase
CFBP6623_RS00935	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CFBP6623_RS00940	COG2201	protein-glutamate methylesterase activity
CFBP6623_RS00945	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS00950	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CFBP6623_RS00960	COG1766	The M ring may be actively involved in energy transduction
CFBP6623_RS00965	COG2771	luxR family
CFBP6623_RS00975	COG0840	transmembrane signaling receptor activity
CFBP6623_RS00975	COG2972	Histidine kinase
CFBP6623_RS00980	COG2205	protein histidine kinase activity
CFBP6623_RS00980	COG2198	Histidine kinase
CFBP6623_RS00980	COG0784	Response regulator, receiver
CFBP6623_RS00990	COG1970	mechanosensitive ion channel activity
CFBP6623_RS00995	COG0436	Aminotransferase
CFBP6623_RS01010	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CFBP6623_RS01015	COG0424	maF-like protein
CFBP6623_RS01020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFBP6623_RS01030	COG5328	Belongs to the UPF0262 family
CFBP6623_RS01035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFBP6623_RS01045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFBP6623_RS01060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP6623_RS01080	COG1338	Plays a role in the flagellum-specific transport system
CFBP6623_RS01090	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CFBP6623_RS01100	COG1706	bacterial-type flagellum-dependent cell motility
CFBP6623_RS01105	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CFBP6623_RS01110	COG4786	Flagellar basal body rod
CFBP6623_RS01115	COG1677	Flagellar hook-basal body complex protein FliE
CFBP6623_RS01120	COG1558	bacterial-type flagellum-dependent cell motility
CFBP6623_RS01125	COG1815	bacterial-type flagellum-dependent cell motility
CFBP6623_RS01135	COG1157	protein secretion by the type III secretion system
CFBP6623_RS01140	COG4786	Flagellar basal body rod
CFBP6623_RS01150	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CFBP6623_RS01155	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP6623_RS01160	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP6623_RS01165	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP6623_RS01170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP6623_RS01185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP6623_RS01195	COG1360	Flagellar Motor Protein
CFBP6623_RS01220	COG1749	Flagellar hook protein flgE
CFBP6623_RS01240	COG5443	negative regulation of bacterial-type flagellum assembly
CFBP6623_RS01245	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CFBP6623_RS01255	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP6623_RS01295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFBP6623_RS01300	COG1609	Transcriptional regulator
CFBP6623_RS01305	COG1653	transport
CFBP6623_RS01310	COG1175	transmembrane transport
CFBP6623_RS01315	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS01320	COG0366	Alpha amylase catalytic
CFBP6623_RS01325	COG3842	ATPase activity
CFBP6623_RS01340	COG0129	dihydroxy-acid dehydratase activity
CFBP6623_RS01345	COG0363	glucosamine-6-phosphate deaminase activity
CFBP6623_RS01350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFBP6623_RS01355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS01365	COG2081	HI0933 family
CFBP6623_RS01385	COG2224	Isocitrate lyase
CFBP6623_RS01400	COG3842	ATPase activity
CFBP6623_RS01405	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP6623_RS01410	COG1177	transmembrane transport
CFBP6623_RS01420	COG2205	protein histidine kinase activity
CFBP6623_RS01430	COG0248	Ppx GppA phosphatase
CFBP6623_RS01435	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CFBP6623_RS01440	COG0477	Major facilitator Superfamily
CFBP6623_RS01480	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFBP6623_RS01485	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFBP6623_RS01495	COG0142	geranyltranstransferase activity
CFBP6623_RS01520	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP6623_RS01525	COG0752	glycyl-tRNA synthetase alpha subunit
CFBP6623_RS01535	COG1704	LemA family
CFBP6623_RS01540	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFBP6623_RS01550	COG0751	glycine-tRNA ligase activity
CFBP6623_RS01560	COG1683	Conserved Protein
CFBP6623_RS01565	COG0840	transmembrane signaling receptor activity
CFBP6623_RS01575	COG0151	Belongs to the GarS family
CFBP6623_RS01580	COG2183	response to ionizing radiation
CFBP6623_RS01585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP6623_RS01610	COG0583	DNA-binding transcription factor activity
CFBP6623_RS01630	COG0306	phosphate transporter
CFBP6623_RS01640	COG0561	phosphatase activity
CFBP6623_RS01645	COG0438	transferase activity, transferring glycosyl groups
CFBP6623_RS01650	COG2186	Transcriptional regulator
CFBP6623_RS01665	COG0583	DNA-binding transcription factor activity
CFBP6623_RS01670	COG0277	FAD linked oxidase domain protein
CFBP6623_RS01680	COG0277	FAD linked oxidase domain protein
CFBP6623_RS01685	COG0247	lactate metabolic process
CFBP6623_RS01695	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6623_RS01700	COG2818	Glycosylase
CFBP6623_RS01710	COG2855	membrane
CFBP6623_RS01715	COG0583	DNA-binding transcription factor activity
CFBP6623_RS01745	COG0124	histidyl-tRNA synthetase
CFBP6623_RS01755	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFBP6623_RS01760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFBP6623_RS01765	COG2259	Doxx family
CFBP6623_RS01780	COG0459	protein refolding
CFBP6623_RS01785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFBP6623_RS01795	COG0196	riboflavin kinase activity
CFBP6623_RS01800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFBP6623_RS01810	COG0590	tRNA wobble adenosine to inosine editing
CFBP6623_RS01815	COG1187	pseudouridine synthase activity
CFBP6623_RS01820	COG0742	ribosomal rna small subunit methyltransferase
CFBP6623_RS01825	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP6623_RS01830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP6623_RS01830	COG0475	glutathione-regulated potassium exporter activity
CFBP6623_RS01835	COG0312	modulator of DNA gyrase
CFBP6623_RS01850	COG1519	Transferase
CFBP6623_RS01860	COG1663	tetraacyldisaccharide 4'-kinase activity
CFBP6623_RS01870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFBP6623_RS01880	COG5001	Diguanylate cyclase
CFBP6623_RS01880	COG3300	MHYT domain
CFBP6623_RS01885	COG3386	PFAM SMP-30 Gluconolaconase
CFBP6623_RS01890	COG0800	Aldolase
CFBP6623_RS01895	COG3734	2-keto-3-deoxy-galactonokinase
CFBP6623_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS01910	COG2197	response regulator
CFBP6623_RS01915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6623_RS01925	COG0598	Magnesium transport protein CorA
CFBP6623_RS01930	COG3158	transport of potassium into the cell
CFBP6623_RS01945	COG0356	it plays a direct role in the translocation of protons across the membrane
CFBP6623_RS01955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP6623_RS01960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP6623_RS01970	COG0300	oxidoreductase activity
CFBP6623_RS01975	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFBP6623_RS02000	COG0009	L-threonylcarbamoyladenylate synthase
CFBP6623_RS02010	COG4638	Rieske (2fe-2S)
CFBP6623_RS02035	COG1960	acyl-CoA dehydrogenase activity
CFBP6623_RS02050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFBP6623_RS02055	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CFBP6623_RS02060	COG0840	transmembrane signaling receptor activity
CFBP6623_RS02060	COG2972	Histidine kinase
CFBP6623_RS02070	COG1522	sequence-specific DNA binding
CFBP6623_RS02095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFBP6623_RS02100	COG1741	Belongs to the pirin family
CFBP6623_RS02110	COG1722	exodeoxyribonuclease VII activity
CFBP6623_RS02115	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFBP6623_RS02120	COG1268	BioY protein
CFBP6623_RS02125	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFBP6623_RS02130	COG1122	ATPase activity
CFBP6623_RS02135	COG3214	Protein conserved in bacteria
CFBP6623_RS02140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP6623_RS02140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP6623_RS02145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFBP6623_RS02165	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP6623_RS02180	COG0259	pyridoxamine-phosphate oxidase activity
CFBP6623_RS02200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP6623_RS02210	COG0312	modulator of DNA gyrase
CFBP6623_RS02225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP6623_RS02230	COG0109	protoheme IX farnesyltransferase activity
CFBP6623_RS02240	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CFBP6623_RS02255	COG3346	SURF1 family
CFBP6623_RS02260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CFBP6623_RS02265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFBP6623_RS02270	COG0328	RNA-DNA hybrid ribonuclease activity
CFBP6623_RS02280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFBP6623_RS02280	COG0678	peroxiredoxin activity
CFBP6623_RS02290	COG1678	Uncharacterized ACR, COG1678
CFBP6623_RS02295	COG3237	CsbD-like
CFBP6623_RS02305	COG5001	Diguanylate cyclase
CFBP6623_RS02305	COG3300	MHYT domain
CFBP6623_RS02310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP6623_RS02315	COG0612	Peptidase, M16
CFBP6623_RS02340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP6623_RS02345	COG1802	Transcriptional regulator
CFBP6623_RS02365	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CFBP6623_RS02375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6623_RS02385	COG1194	a g-specific adenine glycosylase
CFBP6623_RS02400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFBP6623_RS02405	COG1196	nuclear chromosome segregation
CFBP6623_RS02410	COG2514	catechol 2,3-dioxygenase activity
CFBP6623_RS02415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFBP6623_RS02415	COG0574	Belongs to the PEP-utilizing enzyme family
CFBP6623_RS02425	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CFBP6623_RS02430	COG1301	dicarboxylic acid transport
CFBP6623_RS02475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP6623_RS02490	COG0210	DNA helicase
CFBP6623_RS02515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CFBP6623_RS02535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CFBP6623_RS02570	COG0579	oxidoreductase
CFBP6623_RS02590	COG2895	sulfate adenylyltransferase (ATP) activity
CFBP6623_RS02595	COG0175	sulfate reduction
CFBP6623_RS02600	COG0175	sulfate reduction
CFBP6623_RS02605	COG1959	2 iron, 2 sulfur cluster binding
CFBP6623_RS02615	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CFBP6623_RS02620	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP6623_RS02625	COG4208	sulfate ABC transporter
CFBP6623_RS02630	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP6623_RS02645	COG2199	diguanylate cyclase activity
CFBP6623_RS02645	COG2200	EAL domain
CFBP6623_RS02645	COG2203	Gaf domain
CFBP6623_RS02655	COG1309	transcriptional regulator
CFBP6623_RS02660	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS02670	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CFBP6623_RS02715	COG0477	Major facilitator Superfamily
CFBP6623_RS02735	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CFBP6623_RS02735	COG1793	dna ligase
CFBP6623_RS02750	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6623_RS02755	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6623_RS02770	COG1846	Transcriptional regulator
CFBP6623_RS02775	COG1764	response to oxidative stress
CFBP6623_RS02815	COG0488	(ABC) transporter
CFBP6623_RS02820	COG0433	COG0433 Predicted ATPase
CFBP6623_RS02830	COG1733	regulation of RNA biosynthetic process
CFBP6623_RS02835	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CFBP6623_RS02855	COG0656	L-ascorbic acid biosynthetic process
CFBP6623_RS02860	COG3781	membrane
CFBP6623_RS02865	COG2378	regulation of single-species biofilm formation
CFBP6623_RS02875	COG4106	trans-aconitate 2-methyltransferase activity
CFBP6623_RS02880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP6623_RS02885	COG0840	transmembrane signaling receptor activity
CFBP6623_RS02890	COG0583	DNA-binding transcription factor activity
CFBP6623_RS02905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP6623_RS02925	COG3909	cytochrome
CFBP6623_RS02930	COG2010	Cytochrome c
CFBP6623_RS02965	COG0789	Transcriptional regulator
CFBP6623_RS02995	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP6623_RS03020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6623_RS03030	COG2169	Transcriptional regulator
CFBP6623_RS03030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP6623_RS03040	COG2514	catechol 2,3-dioxygenase activity
CFBP6623_RS03055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CFBP6623_RS03060	COG1272	protein, Hemolysin III
CFBP6623_RS03070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP6623_RS03075	COG2111	Na H antiporter
CFBP6623_RS03075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFBP6623_RS03080	COG2111	Na H antiporter
CFBP6623_RS03085	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP6623_RS03090	COG0651	ATP synthesis coupled electron transport
CFBP6623_RS03095	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP6623_RS03100	COG2212	antiporter activity
CFBP6623_RS03105	COG1320	monovalent cation:proton antiporter activity
CFBP6623_RS03110	COG4957	zinc ion binding
CFBP6623_RS03125	COG2166	iron-sulfur cluster assembly
CFBP6623_RS03135	COG2205	protein histidine kinase activity
CFBP6623_RS03185	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP6623_RS03190	COG2983	Belongs to the UPF0260 family
CFBP6623_RS03245	COG1621	beta-fructofuranosidase activity
CFBP6623_RS03250	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFBP6623_RS03310	COG4695	Portal protein
CFBP6623_RS03425	COG4235	cytochrome complex assembly
CFBP6623_RS03430	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CFBP6623_RS03435	COG1138	Cytochrome C-type biogenesis protein
CFBP6623_RS03440	COG3088	subunit of a heme lyase
CFBP6623_RS03445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6623_RS03460	COG3011	Protein conserved in bacteria
CFBP6623_RS03465	COG3713	MltA-interacting MipA family protein
CFBP6623_RS03470	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFBP6623_RS03480	COG2202	Pas domain
CFBP6623_RS03480	COG2205	protein histidine kinase activity
CFBP6623_RS03490	COG0308	aminopeptidase N
CFBP6623_RS03500	COG0697	spore germination
CFBP6623_RS03520	COG0443	Heat shock 70 kDa protein
CFBP6623_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS03550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP6623_RS03575	COG1733	regulation of RNA biosynthetic process
CFBP6623_RS03580	COG1968	undecaprenyl-diphosphatase activity
CFBP6623_RS03585	COG2239	Acts as a magnesium transporter
CFBP6623_RS03590	COG2814	Major facilitator Superfamily
CFBP6623_RS03615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFBP6623_RS03640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP6623_RS03685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFBP6623_RS03690	COG0741	lytic transglycosylase activity
CFBP6623_RS03695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6623_RS03700	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFBP6623_RS03705	COG0840	transmembrane signaling receptor activity
CFBP6623_RS03715	COG1758	RNA polymerase activity
CFBP6623_RS03740	COG0736	holo-[acyl-carrier-protein] synthase activity
CFBP6623_RS03745	COG0681	Belongs to the peptidase S26 family
CFBP6623_RS03750	COG0571	ribonuclease III activity
CFBP6623_RS03755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFBP6623_RS03765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP6623_RS03770	COG0784	Response regulator, receiver
CFBP6623_RS03775	COG1381	Involved in DNA repair and RecF pathway recombination
CFBP6623_RS03785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP6623_RS03795	COG1418	mRNA catabolic process
CFBP6623_RS03805	COG0346	lactoylglutathione lyase activity
CFBP6623_RS03815	COG1116	anion transmembrane transporter activity
CFBP6623_RS03820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6623_RS03825	COG3443	Belongs to the bacterial solute-binding protein 9 family
CFBP6623_RS03830	COG0668	transmembrane transport
CFBP6623_RS03840	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CFBP6623_RS03870	COG1742	UPF0060 membrane protein
CFBP6623_RS03885	COG1183	phosphatidylcholine synthase activity
CFBP6623_RS03890	COG0688	phosphatidylethanolamine metabolic process
CFBP6623_RS03895	COG5265	(ABC) transporter
CFBP6623_RS03940	COG2852	Protein conserved in bacteria
CFBP6623_RS03945	COG0215	cysteine-tRNA ligase activity
CFBP6623_RS03950	COG4221	oxidoreductase activity
CFBP6623_RS03955	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFBP6623_RS03960	COG1286	toxin biosynthetic process
CFBP6623_RS03980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP6623_RS03990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CFBP6623_RS04000	COG0305	Participates in initiation and elongation during chromosome replication
CFBP6623_RS04025	COG0359	binds to the 23S rRNA
CFBP6623_RS04035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFBP6623_RS04040	COG0360	Binds together with S18 to 16S ribosomal RNA
CFBP6623_RS04055	COG0667	Aldo Keto reductase
CFBP6623_RS04060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CFBP6623_RS04070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6623_RS04075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP6623_RS04080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFBP6623_RS04085	COG1561	YicC-like family, N-terminal region
CFBP6623_RS04090	COG0194	GDP metabolic process
CFBP6623_RS04095	COG0400	carboxylic ester hydrolase activity
CFBP6623_RS04100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFBP6623_RS04105	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP6623_RS04115	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CFBP6623_RS04130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP6623_RS04150	COG2203	Gaf domain
CFBP6623_RS04150	COG5001	Diguanylate cyclase
CFBP6623_RS04150	COG3706	GGDEF domain
CFBP6623_RS04150	COG4251	negative regulation of phosphorylation
CFBP6623_RS04155	COG5001	Diguanylate cyclase
CFBP6623_RS04155	COG3300	MHYT domain
CFBP6623_RS04160	COG4191	Histidine kinase
CFBP6623_RS04165	COG4566	intracellular signal transduction
CFBP6623_RS04175	COG0488	(ABC) transporter
CFBP6623_RS04180	COG3706	GGDEF domain
CFBP6623_RS04190	COG0105	UTP biosynthetic process
CFBP6623_RS04210	COG0314	molybdopterin synthase activity
CFBP6623_RS04220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFBP6623_RS04225	COG0322	excinuclease ABC activity
CFBP6623_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS04240	COG0625	glutathione transferase activity
CFBP6623_RS04255	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CFBP6623_RS04260	COG0243	molybdopterin cofactor binding
CFBP6623_RS04285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFBP6623_RS04290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFBP6623_RS04300	COG0628	permease
CFBP6623_RS04305	COG2255	four-way junction helicase activity
CFBP6623_RS04310	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CFBP6623_RS04315	COG0248	Ppx GppA phosphatase
CFBP6623_RS04340	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CFBP6623_RS04350	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFBP6623_RS04355	COG0477	Major facilitator Superfamily
CFBP6623_RS04360	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFBP6623_RS04365	COG4452	Inner membrane protein CreD
CFBP6623_RS04370	COG0840	transmembrane signaling receptor activity
CFBP6623_RS04375	COG0659	secondary active sulfate transmembrane transporter activity
CFBP6623_RS04385	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP6623_RS04390	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CFBP6623_RS04405	COG0113	porphobilinogen synthase activity
CFBP6623_RS04425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFBP6623_RS04430	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFBP6623_RS04435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP6623_RS04435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP6623_RS04445	COG1280	lysine exporter protein (LysE YggA)
CFBP6623_RS04450	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFBP6623_RS04455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFBP6623_RS04460	COG2814	Major facilitator Superfamily
CFBP6623_RS04465	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CFBP6623_RS04485	COG0416	fatty acid biosynthetic process
CFBP6623_RS04490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFBP6623_RS04495	COG0776	regulation of translation
CFBP6623_RS04530	COG0601	transmembrane transport
CFBP6623_RS04535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS04540	COG0444	Belongs to the ABC transporter superfamily
CFBP6623_RS04550	COG0747	negative chemotaxis
CFBP6623_RS04560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFBP6623_RS04565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFBP6623_RS04580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFBP6623_RS04585	COG0583	DNA-binding transcription factor activity
CFBP6623_RS04595	COG0737	Belongs to the 5'-nucleotidase family
CFBP6623_RS04620	COG2897	thiosulfate sulfurtransferase activity
CFBP6623_RS04635	COG0415	Belongs to the DNA photolyase family
CFBP6623_RS04645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP6623_RS04675	COG3932	Exopolysaccharide synthesis, ExoD
CFBP6623_RS04680	COG1238	metal cluster binding
CFBP6623_RS04765	COG1612	heme a metabolic process
CFBP6623_RS04775	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFBP6623_RS04780	COG0010	Belongs to the arginase family
CFBP6623_RS04785	COG1396	sequence-specific DNA binding
CFBP6623_RS04790	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CFBP6623_RS04795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFBP6623_RS04800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFBP6623_RS04810	COG1832	CoA-binding protein
CFBP6623_RS04830	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS04840	COG2199	diguanylate cyclase activity
CFBP6623_RS04845	COG0740	serine-type endopeptidase activity
CFBP6623_RS04850	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFBP6623_RS04865	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFBP6623_RS04875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP6623_RS04895	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6623_RS04900	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6623_RS04905	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6623_RS04915	COG0649	NAD binding
CFBP6623_RS04925	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CFBP6623_RS04930	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CFBP6623_RS04940	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CFBP6623_RS04945	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6623_RS04955	COG0713	ATP synthesis coupled electron transport
CFBP6623_RS04970	COG1007	ATP synthesis coupled electron transport
CFBP6623_RS04990	COG0442	prolyl-tRNA aminoacylation
CFBP6623_RS05000	COG1136	(ABC) transporter
CFBP6623_RS05020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP6623_RS05030	COG0784	Response regulator, receiver
CFBP6623_RS05040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFBP6623_RS05045	COG0477	Major facilitator Superfamily
CFBP6623_RS05060	COG0557	exoribonuclease II activity
CFBP6623_RS05065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFBP6623_RS05075	COG0758	DNA mediated transformation
CFBP6623_RS05080	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CFBP6623_RS05090	COG0540	Belongs to the ATCase OTCase family
CFBP6623_RS05095	COG1960	acyl-CoA dehydrogenase activity
CFBP6623_RS05100	COG0456	acetyltransferase
CFBP6623_RS05120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFBP6623_RS05125	COG2824	Alkylphosphonate utilization operon protein PhnA
CFBP6623_RS05130	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CFBP6623_RS05135	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP6623_RS05140	COG0154	amidase activity
CFBP6623_RS05145	COG3811	Belongs to the UPF0386 family
CFBP6623_RS05160	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP6623_RS05170	COG0456	acetyltransferase
CFBP6623_RS05185	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CFBP6623_RS05190	COG0439	Biotin carboxylase
CFBP6623_RS05195	COG0511	ligase activity, forming carbon-carbon bonds
CFBP6623_RS05200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP6623_RS05210	COG0436	Aminotransferase
CFBP6623_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS05235	COG1530	ribonuclease E activity
CFBP6623_RS05250	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP6623_RS05270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFBP6623_RS05275	COG0384	phenazine biosynthesis protein PhzF
CFBP6623_RS05295	COG0633	Ferredoxin
CFBP6623_RS05305	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFBP6623_RS05310	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFBP6623_RS05315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFBP6623_RS05325	COG3768	UPF0283 membrane protein
CFBP6623_RS05330	COG3106	COG3106 Predicted ATPase
CFBP6623_RS05355	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFBP6623_RS05390	COG0537	adenosine 5'-monophosphoramidase activity
CFBP6623_RS05415	COG0052	Belongs to the universal ribosomal protein uS2 family
CFBP6623_RS05420	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFBP6623_RS05425	COG0528	UMP kinase activity
CFBP6623_RS05430	COG0233	cytoplasmic translational termination
CFBP6623_RS05435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFBP6623_RS05445	COG0750	zinc metalloprotease
CFBP6623_RS05450	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP6623_RS05455	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP6623_RS05460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP6623_RS05465	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP6623_RS05470	COG3494	Protein of unknown function (DUF1009)
CFBP6623_RS05475	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP6623_RS05480	COG0372	Belongs to the citrate synthase family
CFBP6623_RS05495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFBP6623_RS05505	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CFBP6623_RS05510	COG0148	phosphopyruvate hydratase activity
CFBP6623_RS05520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFBP6623_RS05525	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP6623_RS05525	COG0022	dehydrogenase e1 component
CFBP6623_RS05535	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP6623_RS05545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFBP6623_RS05555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFBP6623_RS05560	COG0697	spore germination
CFBP6623_RS05585	COG2867	negative regulation of translational initiation
CFBP6623_RS05595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFBP6623_RS05595	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFBP6623_RS05605	COG3852	Histidine kinase
CFBP6623_RS05610	COG2204	response regulator
CFBP6623_RS05615	COG5000	phosphorelay sensor kinase activity
CFBP6623_RS05620	COG2204	response regulator
CFBP6623_RS05625	COG0569	domain protein
CFBP6623_RS05630	COG1923	regulation of RNA biosynthetic process
CFBP6623_RS05635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFBP6623_RS05640	COG3956	TIGRFAM MazG family protein
CFBP6623_RS05655	COG1648	precorrin-2 dehydrogenase activity
CFBP6623_RS05655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP6623_RS05690	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CFBP6623_RS05705	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP6623_RS05705	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP6623_RS05710	COG0509	glycine decarboxylation via glycine cleavage system
CFBP6623_RS05715	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP6623_RS05740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFBP6623_RS05745	COG0564	pseudouridine synthase activity
CFBP6623_RS05765	COG0251	oxidation-reduction process
CFBP6623_RS05770	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CFBP6623_RS05780	COG1671	Belongs to the UPF0178 family
CFBP6623_RS05795	COG0450	alkyl hydroperoxide reductase
CFBP6623_RS05800	COG0625	glutathione transferase activity
CFBP6623_RS05805	COG2860	membrane
CFBP6623_RS05830	COG2801	Transposase and inactivated derivatives
CFBP6623_RS05840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6623_RS05840	COG3320	Male sterility
CFBP6623_RS05845	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS05860	COG3321	synthase
CFBP6623_RS05860	COG0604	alcohol dehydrogenase
CFBP6623_RS05875	COG2977	Belongs to the P-Pant transferase superfamily
CFBP6623_RS05905	COG0084	hydrolase, TatD family'
CFBP6623_RS05910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP6623_RS05920	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFBP6623_RS06145	COG3750	Belongs to the UPF0335 family
CFBP6623_RS06205	COG1396	sequence-specific DNA binding
CFBP6623_RS06210	COG2358	TRAP transporter, solute receptor (TAXI family
CFBP6623_RS06305	COG0582	viral genome integration into host DNA
CFBP6623_RS06345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP6623_RS06350	COG2095	MarC family integral membrane protein
CFBP6623_RS06355	COG0517	IMP dehydrogenase activity
CFBP6623_RS06355	COG0617	tRNA 3'-terminal CCA addition
CFBP6623_RS06355	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CFBP6623_RS06365	COG0629	single-stranded DNA binding
CFBP6623_RS06370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFBP6623_RS06380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFBP6623_RS06400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP6623_RS06405	COG1121	(ABC) transporter
CFBP6623_RS06425	COG0667	Aldo Keto reductase
CFBP6623_RS06435	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFBP6623_RS06520	COG2239	Acts as a magnesium transporter
CFBP6623_RS06525	COG0243	molybdopterin cofactor binding
CFBP6623_RS06535	COG0242	peptide deformylase activity
CFBP6623_RS06550	COG2202	Pas domain
CFBP6623_RS06550	COG2205	protein histidine kinase activity
CFBP6623_RS06565	COG0321	lipoyl(octanoyl) transferase activity
CFBP6623_RS06570	COG1064	alcohol dehydrogenase
CFBP6623_RS06600	COG1862	Preprotein translocase
CFBP6623_RS06620	COG2124	cytochrome p450
CFBP6623_RS06635	COG0596	Alpha beta hydrolase
CFBP6623_RS06650	COG0626	cystathionine gamma-synthase activity
CFBP6623_RS06655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6623_RS06660	COG4597	amino acid ABC transporter
CFBP6623_RS06665	COG0765	amino acid transport
CFBP6623_RS06670	COG1126	abc transporter atp-binding protein
CFBP6623_RS06690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFBP6623_RS06705	COG0436	Aminotransferase
CFBP6623_RS06735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP6623_RS06745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP6623_RS06750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6623_RS06755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP6623_RS06775	COG3243	poly(R)-hydroxyalkanoic acid synthase
CFBP6623_RS06780	COG1489	DNA binding
CFBP6623_RS06785	COG0024	Methionine aminopeptidase
CFBP6623_RS06790	COG2003	Belongs to the UPF0758 family
CFBP6623_RS06805	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CFBP6623_RS06820	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFBP6623_RS06825	COG0546	phosphoglycolate phosphatase activity
CFBP6623_RS06840	COG0114	fumarate hydratase activity
CFBP6623_RS06845	COG0504	CTP synthase activity
CFBP6623_RS06855	COG0149	triose-phosphate isomerase activity
CFBP6623_RS06865	COG0187	DNA topoisomerase II activity
CFBP6623_RS06875	COG0740	serine-type endopeptidase activity
CFBP6623_RS06885	COG0640	Transcriptional regulator
CFBP6623_RS06890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFBP6623_RS06895	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS06915	COG3264	Mechanosensitive ion channel
CFBP6623_RS06915	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CFBP6623_RS06985	COG1127	ABC transporter
CFBP6623_RS06990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFBP6623_RS06995	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6623_RS07005	COG0280	phosphate acetyltransferase
CFBP6623_RS07005	COG0281	malic enzyme
CFBP6623_RS07025	COG0778	Nitroreductase
CFBP6623_RS07030	COG0823	Involved in the tonB-independent uptake of proteins
CFBP6623_RS07045	COG1368	sulfuric ester hydrolase activity
CFBP6623_RS07070	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFBP6623_RS07095	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFBP6623_RS07115	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFBP6623_RS07150	COG0512	Glutamine amidotransferase of anthranilate synthase
CFBP6623_RS07150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFBP6623_RS07155	COG0343	queuine tRNA-ribosyltransferase activity
CFBP6623_RS07160	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFBP6623_RS07175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFBP6623_RS07200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFBP6623_RS07205	COG0134	indole-3-glycerol-phosphate synthase activity
CFBP6623_RS07210	COG0315	cyclic pyranopterin monophosphate synthase activity
CFBP6623_RS07215	COG0303	'Molybdopterin
CFBP6623_RS07220	COG3706	GGDEF domain
CFBP6623_RS07230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP6623_RS07230	COG0475	glutathione-regulated potassium exporter activity
CFBP6623_RS07240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFBP6623_RS07245	COG0697	spore germination
CFBP6623_RS07250	COG2814	Major facilitator Superfamily
CFBP6623_RS07255	COG0746	molybdenum cofactor guanylyltransferase activity
CFBP6623_RS07260	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFBP6623_RS07265	COG0739	heme binding
CFBP6623_RS07270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP6623_RS07275	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CFBP6623_RS07280	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP6623_RS07285	COG0805	protein transport
CFBP6623_RS07290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP6623_RS07295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP6623_RS07300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFBP6623_RS07305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFBP6623_RS07310	COG1472	Belongs to the glycosyl hydrolase 3 family
CFBP6623_RS07320	COG0018	arginyl-trna synthetase
CFBP6623_RS07325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CFBP6623_RS07330	COG0316	Belongs to the HesB IscA family
CFBP6623_RS07355	COG0525	valine-tRNA ligase activity
CFBP6623_RS07365	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP6623_RS07395	COG0655	NAD(P)H dehydrogenase (quinone) activity
CFBP6623_RS07400	COG1546	Belongs to the CinA family
CFBP6623_RS07400	COG1058	Belongs to the CinA family
CFBP6623_RS07405	COG0589	response to stress
CFBP6623_RS07410	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CFBP6623_RS07420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFBP6623_RS07460	COG0433	COG0433 Predicted ATPase
CFBP6623_RS07470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFBP6623_RS07490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP6623_RS07525	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP6623_RS07540	COG1132	(ABC) transporter
CFBP6623_RS07545	COG0628	permease
CFBP6623_RS07580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFBP6623_RS07590	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFBP6623_RS07600	COG0302	gtp cyclohydrolase
CFBP6623_RS07605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFBP6623_RS07610	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP6623_RS07620	COG0516	GMP reductase activity
CFBP6623_RS07620	COG0517	IMP dehydrogenase activity
CFBP6623_RS07650	COG1760	l-serine dehydratase
CFBP6623_RS07690	COG0583	DNA-binding transcription factor activity
CFBP6623_RS07705	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFBP6623_RS07705	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFBP6623_RS07715	COG0347	Belongs to the P(II) protein family
CFBP6623_RS07720	COG0174	glutamine synthetase
CFBP6623_RS07750	COG0697	spore germination
CFBP6623_RS07760	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFBP6623_RS07770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFBP6623_RS07785	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFBP6623_RS07795	COG3153	acetyltransferase
CFBP6623_RS07800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP6623_RS07805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFBP6623_RS07810	COG2186	Transcriptional regulator
CFBP6623_RS07820	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS07825	COG4603	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS07830	COG3845	ABC transporter
CFBP6623_RS07835	COG1183	phosphatidylcholine synthase activity
CFBP6623_RS07840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP6623_RS07845	COG0679	Auxin Efflux Carrier
CFBP6623_RS07850	COG0785	Cytochrome C biogenesis protein
CFBP6623_RS07870	COG0346	lactoylglutathione lyase activity
CFBP6623_RS07875	COG1278	Cold shock
CFBP6623_RS07920	COG0084	hydrolase, TatD family'
CFBP6623_RS07975	COG0798	PFAM Bile acid sodium symporter
CFBP6623_RS07985	COG0431	NADPH-dependent FMN reductase
CFBP6623_RS08065	COG0577	efflux transmembrane transporter activity
CFBP6623_RS08065	COG1136	(ABC) transporter
CFBP6623_RS08070	COG0577	efflux transmembrane transporter activity
CFBP6623_RS08070	COG1136	(ABC) transporter
CFBP6623_RS08080	COG2151	metal-sulfur cluster biosynthetic enzyme
CFBP6623_RS08085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFBP6623_RS08090	COG0719	Fe-S assembly protein
CFBP6623_RS08095	COG0396	ATPase activity
CFBP6623_RS08105	COG0719	Fe-S assembly protein
CFBP6623_RS08110	COG1104	cysteine desulfurase activity
CFBP6623_RS08115	COG2945	thiolester hydrolase activity
CFBP6623_RS08120	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFBP6623_RS08125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFBP6623_RS08135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFBP6623_RS08140	COG2833	Protein of unknown function (DUF455)
CFBP6623_RS08145	COG0739	heme binding
CFBP6623_RS08150	COG0513	Belongs to the DEAD box helicase family
CFBP6623_RS08175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFBP6623_RS08185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP6623_RS08190	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP6623_RS08195	COG0047	phosphoribosylformylglycinamidine synthase activity
CFBP6623_RS08210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6623_RS08215	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP6623_RS08240	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CFBP6623_RS08245	COG2814	Major facilitator Superfamily
CFBP6623_RS08250	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6623_RS08255	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6623_RS08260	COG0037	tRNA processing
CFBP6623_RS08265	COG2066	Belongs to the glutaminase family
CFBP6623_RS08270	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFBP6623_RS08275	COG0861	Integral membrane protein TerC family
CFBP6623_RS08290	COG1280	lysine exporter protein (LysE YggA)
CFBP6623_RS08305	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFBP6623_RS08310	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CFBP6623_RS08320	COG0538	isocitrate dehydrogenase activity
CFBP6623_RS08335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFBP6623_RS08340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFBP6623_RS08345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6623_RS08350	COG2313	pseudouridylate synthase activity
CFBP6623_RS08365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6623_RS08370	COG4215	(ABC) transporter
CFBP6623_RS08380	COG5425	PFAM Usg family protein
CFBP6623_RS08395	COG1522	sequence-specific DNA binding
CFBP6623_RS08400	COG1573	uracil-dna glycosylase
CFBP6623_RS08410	COG2205	protein histidine kinase activity
CFBP6623_RS08410	COG2202	Pas domain
CFBP6623_RS08420	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CFBP6623_RS08425	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CFBP6623_RS08440	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP6623_RS08445	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS08450	COG1129	ABC transporter
CFBP6623_RS08460	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS08465	COG3959	Transketolase, thiamine diphosphate binding domain
CFBP6623_RS08470	COG3958	Transketolase
CFBP6623_RS08475	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP6623_RS08480	COG2390	Transcriptional regulator
CFBP6623_RS08490	COG0842	Transport permease protein
CFBP6623_RS08495	COG1131	(ABC) transporter
CFBP6623_RS08500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6623_RS08500	COG0730	response to heat
CFBP6623_RS08515	COG0840	transmembrane signaling receptor activity
CFBP6623_RS08525	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFBP6623_RS08530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6623_RS08545	COG0129	dihydroxy-acid dehydratase activity
CFBP6623_RS08550	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFBP6623_RS08555	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CFBP6623_RS08565	COG3739	integral membrane protein
CFBP6623_RS08570	COG0203	ribosomal protein L17
CFBP6623_RS08575	COG0202	RNA polymerase activity
CFBP6623_RS08580	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFBP6623_RS08585	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFBP6623_RS08590	COG0563	adenylate kinase activity
CFBP6623_RS08595	COG0201	protein transport
CFBP6623_RS08600	COG0200	Binds to the 23S rRNA
CFBP6623_RS08605	COG1841	ribosomal large subunit assembly
CFBP6623_RS08610	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFBP6623_RS08615	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFBP6623_RS08620	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFBP6623_RS08625	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFBP6623_RS08630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFBP6623_RS08635	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFBP6623_RS08640	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFBP6623_RS08645	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFBP6623_RS08650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFBP6623_RS08655	COG0255	Belongs to the universal ribosomal protein uL29 family
CFBP6623_RS08660	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFBP6623_RS08665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFBP6623_RS08670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFBP6623_RS08675	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFBP6623_RS08680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFBP6623_RS08685	COG0089	rRNA binding
CFBP6623_RS08690	COG0088	Forms part of the polypeptide exit tunnel
CFBP6623_RS08695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFBP6623_RS08700	COG0051	transcription antitermination factor activity, RNA binding
CFBP6623_RS08705	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP6623_RS08710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFBP6623_RS08715	COG0049	tRNA binding
CFBP6623_RS08720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFBP6623_RS08740	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFBP6623_RS08745	COG0085	RNA polymerase activity
CFBP6623_RS08750	COG0222	ribosome binding
CFBP6623_RS08755	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFBP6623_RS08760	COG0081	regulation of translation
CFBP6623_RS08765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFBP6623_RS08775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFBP6623_RS08790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP6623_RS08795	COG0861	Integral membrane protein TerC family
CFBP6623_RS08825	COG1132	(ABC) transporter
CFBP6623_RS08840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP6623_RS08845	COG1607	acyl-coa hydrolase
CFBP6623_RS08870	COG2910	NAD(P)H-binding
CFBP6623_RS08875	COG1733	regulation of RNA biosynthetic process
CFBP6623_RS08880	COG0454	-acetyltransferase
CFBP6623_RS08880	COG0456	acetyltransferase
CFBP6623_RS08890	COG0556	nucleotide-excision repair
CFBP6623_RS08900	COG2382	esterase
CFBP6623_RS08920	COG0484	heat shock protein binding
CFBP6623_RS09085	COG3842	ATPase activity
CFBP6623_RS09095	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6623_RS09100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6623_RS09110	COG4115	mRNA cleavage
CFBP6623_RS09120	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFBP6623_RS09135	COG2207	Transcriptional regulator
CFBP6623_RS09140	COG1064	alcohol dehydrogenase
CFBP6623_RS09145	COG1252	NADH dehydrogenase
CFBP6623_RS09150	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFBP6623_RS09155	COG2197	response regulator
CFBP6623_RS09160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP6623_RS09165	COG1090	epimerase
CFBP6623_RS09205	COG0656	L-ascorbic acid biosynthetic process
CFBP6623_RS09220	COG0440	acetolactate synthase activity
CFBP6623_RS09225	COG0028	Belongs to the TPP enzyme family
CFBP6623_RS09235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFBP6623_RS09240	COG0560	Phosphoserine phosphatase
CFBP6623_RS09240	COG3830	Belongs to the UPF0237 family
CFBP6623_RS09250	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS09260	COG0330	HflC and HflK could
CFBP6623_RS09265	COG0330	HflC and HflK could
CFBP6623_RS09275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFBP6623_RS09315	COG0277	FAD linked oxidase domain protein
CFBP6623_RS09320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6623_RS09360	COG1335	isochorismatase
CFBP6623_RS09390	COG2264	protein methyltransferase activity
CFBP6623_RS09395	COG1999	signal sequence binding
CFBP6623_RS09400	COG0835	chemotaxis
CFBP6623_RS09415	COG0583	DNA-binding transcription factor activity
CFBP6623_RS09425	COG1247	-acetyltransferase
CFBP6623_RS09435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFBP6623_RS09445	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP6623_RS09455	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP6623_RS09460	COG0849	cell division
CFBP6623_RS09465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFBP6623_RS09470	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFBP6623_RS09475	COG0477	Major facilitator Superfamily
CFBP6623_RS09485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFBP6623_RS09490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFBP6623_RS09495	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFBP6623_RS09505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFBP6623_RS09510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFBP6623_RS09520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFBP6623_RS09535	COG0275	rRNA processing
CFBP6623_RS09540	COG2001	Belongs to the MraZ family
CFBP6623_RS09545	COG0604	alcohol dehydrogenase
CFBP6623_RS09545	COG3321	synthase
CFBP6623_RS09550	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS09580	COG3023	N-Acetylmuramoyl-L-alanine amidase
CFBP6623_RS09610	COG4106	trans-aconitate 2-methyltransferase activity
CFBP6623_RS09630	COG2226	methyltransferase
CFBP6623_RS09640	COG2267	carboxylic ester hydrolase activity
CFBP6623_RS09645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP6623_RS09660	COG0251	oxidation-reduction process
CFBP6623_RS09675	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6623_RS09680	COG2814	Major facilitator Superfamily
CFBP6623_RS09700	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS09705	COG0174	glutamine synthetase
CFBP6623_RS09710	COG0531	amino acid
CFBP6623_RS09720	COG1737	Transcriptional regulator
CFBP6623_RS09745	COG3842	ATPase activity
CFBP6623_RS09765	COG0477	Major facilitator Superfamily
CFBP6623_RS09805	COG2968	Membrane
CFBP6623_RS09815	COG0432	Pfam Uncharacterised protein family UPF0047
CFBP6623_RS09835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP6623_RS09840	COG0358	DNA primase activity
CFBP6623_RS09860	COG0505	Belongs to the CarA family
CFBP6623_RS09865	COG0534	Mate efflux family protein
CFBP6623_RS09880	COG2321	neutral zinc metallopeptidase
CFBP6623_RS09895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFBP6623_RS09905	COG3706	GGDEF domain
CFBP6623_RS09910	COG1573	uracil-dna glycosylase
CFBP6623_RS09920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFBP6623_RS09930	COG1522	sequence-specific DNA binding
CFBP6623_RS09935	COG0492	ferredoxin-NADP+ reductase activity
CFBP6623_RS09940	COG0583	DNA-binding transcription factor activity
CFBP6623_RS09950	COG1902	pentaerythritol trinitrate reductase activity
CFBP6623_RS09980	COG0387	Pfam Sodium calcium exchanger
CFBP6623_RS09985	COG0436	Aminotransferase
CFBP6623_RS09990	COG2199	diguanylate cyclase activity
CFBP6623_RS09990	COG2200	EAL domain
CFBP6623_RS10005	COG1278	Cold shock
CFBP6623_RS10010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6623_RS10025	COG1846	Transcriptional regulator
CFBP6623_RS10030	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS10035	COG2205	protein histidine kinase activity
CFBP6623_RS10040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP6623_RS10060	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFBP6623_RS10070	COG1496	oxidoreductase activity
CFBP6623_RS10085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFBP6623_RS10105	COG0463	Glycosyl transferase, family 2
CFBP6623_RS10110	COG0840	transmembrane signaling receptor activity
CFBP6623_RS10115	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS10125	COG3300	MHYT domain
CFBP6623_RS10125	COG5001	Diguanylate cyclase
CFBP6623_RS10130	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFBP6623_RS10135	COG5001	Diguanylate cyclase
CFBP6623_RS10145	COG0193	aminoacyl-tRNA hydrolase activity
CFBP6623_RS10155	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFBP6623_RS10160	COG0012	GTP binding
CFBP6623_RS10175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFBP6623_RS10180	COG2857	Cytochrome c1
CFBP6623_RS10180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CFBP6623_RS10200	COG1132	(ABC) transporter
CFBP6623_RS10210	COG1132	(ABC) transporter
CFBP6623_RS10215	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CFBP6623_RS10220	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFBP6623_RS10235	COG0408	coproporphyrinogen oxidase activity
CFBP6623_RS10250	COG0617	tRNA 3'-terminal CCA addition
CFBP6623_RS10255	COG0494	nUDIX hydrolase
CFBP6623_RS10265	COG0714	Associated with various cellular activities
CFBP6623_RS10285	COG0454	-acetyltransferase
CFBP6623_RS10305	COG0477	Major facilitator Superfamily
CFBP6623_RS10320	COG0435	Glutathione S-transferase
CFBP6623_RS10325	COG0494	nUDIX hydrolase
CFBP6623_RS10340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFBP6623_RS10355	COG3135	benzoate transporter
CFBP6623_RS10380	COG0740	serine-type endopeptidase activity
CFBP6623_RS10395	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFBP6623_RS10400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFBP6623_RS10425	COG4175	Glycine betaine
CFBP6623_RS10440	COG1435	thymidine kinase activity
CFBP6623_RS10460	COG2862	Uncharacterized protein family, UPF0114
CFBP6623_RS10465	COG4771	TonB-dependent receptor
CFBP6623_RS10465	COG1629	transport
CFBP6623_RS10475	COG0512	Glutamine amidotransferase of anthranilate synthase
CFBP6623_RS10475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFBP6623_RS10490	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP6623_RS10505	COG0366	Alpha amylase catalytic
CFBP6623_RS10510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6623_RS10530	COG1160	GTP binding
CFBP6623_RS10550	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CFBP6623_RS10560	COG0024	Methionine aminopeptidase
CFBP6623_RS10575	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS10585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFBP6623_RS10595	COG0583	DNA-binding transcription factor activity
CFBP6623_RS10610	COG0402	S-adenosylhomocysteine deaminase activity
CFBP6623_RS10625	COG1304	FMN binding
CFBP6623_RS10635	COG1309	transcriptional regulator
CFBP6623_RS10640	COG1686	Belongs to the peptidase S11 family
CFBP6623_RS10650	COG2351	hydroxyisourate hydrolase activity
CFBP6623_RS10655	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CFBP6623_RS10670	COG3648	Uricase
CFBP6623_RS10670	COG3195	allantoin biosynthetic process
CFBP6623_RS10680	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP6623_RS10685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS10685	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFBP6623_RS10690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS10690	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFBP6623_RS10695	COG2205	protein histidine kinase activity
CFBP6623_RS10695	COG0784	Response regulator, receiver
CFBP6623_RS10695	COG5002	protein histidine kinase activity
CFBP6623_RS10700	COG0513	Belongs to the DEAD box helicase family
CFBP6623_RS10705	COG0697	spore germination
CFBP6623_RS10710	COG2259	Doxx family
CFBP6623_RS10715	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6623_RS10725	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP6623_RS10735	COG1305	Transglutaminase-like
CFBP6623_RS10755	COG0588	phosphoglycerate mutase activity
CFBP6623_RS10765	COG4214	carbohydrate transport
CFBP6623_RS10775	COG4213	ABC transporter substrate-binding protein
CFBP6623_RS10845	COG4191	Histidine kinase
CFBP6623_RS11110	COG0840	transmembrane signaling receptor activity
CFBP6623_RS11115	COG2814	Major facilitator Superfamily
CFBP6623_RS11145	COG1215	transferase activity, transferring glycosyl groups
CFBP6623_RS11160	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CFBP6623_RS11180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP6623_RS11195	COG2346	COG2346, Truncated hemoglobins
CFBP6623_RS11215	COG1309	transcriptional regulator
CFBP6623_RS11230	COG0494	nUDIX hydrolase
CFBP6623_RS11245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6623_RS11250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6623_RS11275	COG1234	tRNA 3'-trailer cleavage
CFBP6623_RS11280	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFBP6623_RS11285	COG0830	nickel cation binding
CFBP6623_RS11290	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CFBP6623_RS11310	COG0804	urea catabolic process
CFBP6623_RS11315	COG1442	glycosyl transferase family 8
CFBP6623_RS11320	COG3755	Protein conserved in bacteria
CFBP6623_RS11330	COG0832	Belongs to the urease beta subunit family
CFBP6623_RS11335	COG3813	Protein conserved in bacteria
CFBP6623_RS11340	COG0831	urea catabolic process
CFBP6623_RS11345	COG0829	nickel cation binding
CFBP6623_RS11375	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS11390	COG0174	glutamine synthetase
CFBP6623_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS11400	COG0784	Response regulator, receiver
CFBP6623_RS11400	COG5002	protein histidine kinase activity
CFBP6623_RS11400	COG2198	Histidine kinase
CFBP6623_RS11415	COG0726	polysaccharide deacetylase
CFBP6623_RS11450	COG1218	3'(2'),5'-bisphosphate nucleotidase
CFBP6623_RS11530	COG0564	pseudouridine synthase activity
CFBP6623_RS11545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP6623_RS11555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFBP6623_RS11585	COG0346	lactoylglutathione lyase activity
CFBP6623_RS11595	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFBP6623_RS11605	COG2832	Protein of unknown function (DUF454)
CFBP6623_RS11610	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFBP6623_RS11615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6623_RS11620	COG4558	Periplasmic binding protein
CFBP6623_RS11630	COG3721	Heme iron utilization protein
CFBP6623_RS11665	COG2205	protein histidine kinase activity
CFBP6623_RS11710	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6623_RS11715	COG4605	iron ion homeostasis
CFBP6623_RS11720	COG4604	ABC transporter, ATP-binding protein
CFBP6623_RS11725	COG0783	Belongs to the Dps family
CFBP6623_RS11745	COG2814	Major facilitator Superfamily
CFBP6623_RS11755	COG0583	DNA-binding transcription factor activity
CFBP6623_RS11760	COG0657	acetylesterase activity
CFBP6623_RS11765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6623_RS11785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFBP6623_RS11790	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CFBP6623_RS11795	COG0288	reversible hydration of carbon dioxide
CFBP6623_RS11805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFBP6623_RS11825	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CFBP6623_RS11830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP6623_RS11835	COG0778	Nitroreductase
CFBP6623_RS11840	COG2267	carboxylic ester hydrolase activity
CFBP6623_RS11845	COG0251	oxidation-reduction process
CFBP6623_RS11850	COG1335	isochorismatase
CFBP6623_RS11855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS11865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6623_RS11880	COG1175	transmembrane transport
CFBP6623_RS11885	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS11890	COG3842	ATPase activity
CFBP6623_RS11895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6623_RS11905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP6623_RS11920	COG4608	Belongs to the ABC transporter superfamily
CFBP6623_RS11925	COG0444	Belongs to the ABC transporter superfamily
CFBP6623_RS11930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS11935	COG0601	transmembrane transport
CFBP6623_RS11975	COG2814	Major facilitator Superfamily
CFBP6623_RS12000	COG1960	acyl-CoA dehydrogenase activity
CFBP6623_RS12030	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS12040	COG1902	pentaerythritol trinitrate reductase activity
CFBP6623_RS12040	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP6623_RS12055	COG4232	protein-disulfide reductase activity
CFBP6623_RS12060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFBP6623_RS12060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFBP6623_RS12070	COG1388	LysM domain
CFBP6623_RS12070	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6623_RS12080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP6623_RS12090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFBP6623_RS12100	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP6623_RS12105	COG3842	ATPase activity
CFBP6623_RS12150	COG3038	cytochrome b561
CFBP6623_RS12195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP6623_RS12200	COG1309	transcriptional regulator
CFBP6623_RS12205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6623_RS12210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6623_RS12220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFBP6623_RS12225	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CFBP6623_RS12230	COG1509	lysine 2,3-aminomutase activity
CFBP6623_RS12245	COG0583	DNA-binding transcription factor activity
CFBP6623_RS12250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS12255	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFBP6623_RS12260	COG4149	molybdate abc transporter
CFBP6623_RS12265	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CFBP6623_RS12275	COG3191	aminopeptidase activity
CFBP6623_RS12280	COG2022	thiamine diphosphate biosynthetic process
CFBP6623_RS12295	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFBP6623_RS12300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6623_RS12310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP6623_RS12335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP6623_RS12380	COG4166	transmembrane transport
CFBP6623_RS12385	COG0601	transmembrane transport
CFBP6623_RS12390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS12400	COG0438	transferase activity, transferring glycosyl groups
CFBP6623_RS12405	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFBP6623_RS12410	COG3142	Participates in the control of copper homeostasis
CFBP6623_RS12415	COG2814	Major facilitator Superfamily
CFBP6623_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS12435	COG1737	Transcriptional regulator
CFBP6623_RS12445	COG3842	ATPase activity
CFBP6623_RS12455	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS12475	COG2188	Transcriptional regulator
CFBP6623_RS12480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP6623_RS12485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFBP6623_RS12490	COG1940	carbohydrate kinase activity
CFBP6623_RS12500	COG0671	phosphoesterase, PA-phosphatase related
CFBP6623_RS12505	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFBP6623_RS12510	COG0156	8-amino-7-oxononanoate synthase activity
CFBP6623_RS12520	COG0729	surface antigen
CFBP6623_RS12530	COG0835	chemotaxis
CFBP6623_RS12540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFBP6623_RS12545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFBP6623_RS12550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFBP6623_RS12555	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFBP6623_RS12560	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFBP6623_RS12565	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFBP6623_RS12580	COG4974	Belongs to the 'phage' integrase family
CFBP6623_RS12605	COG1280	lysine exporter protein (LysE YggA)
CFBP6623_RS12615	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP6623_RS12625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFBP6623_RS12630	COG0045	succinate-CoA ligase (ADP-forming) activity
CFBP6623_RS12635	COG0039	L-malate dehydrogenase activity
CFBP6623_RS12640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFBP6623_RS12675	COG2264	protein methyltransferase activity
CFBP6623_RS12690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFBP6623_RS12695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFBP6623_RS12700	COG0181	hydroxymethylbilane synthase activity
CFBP6623_RS12735	COG1872	DUF167
CFBP6623_RS12740	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFBP6623_RS12755	COG1217	gtp-binding protein TYPA
CFBP6623_RS12760	COG0339	signal peptide processing
CFBP6623_RS12770	COG1846	Transcriptional regulator
CFBP6623_RS12780	COG0137	argininosuccinate synthase activity
CFBP6623_RS12785	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS12790	COG1280	lysine exporter protein (LysE YggA)
CFBP6623_RS12795	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFBP6623_RS12800	COG4120	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS12810	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CFBP6623_RS12825	COG2154	pterin-4-alpha-carbinolamine dehydratase
CFBP6623_RS12830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFBP6623_RS12835	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CFBP6623_RS12845	COG4181	ATPase activity
CFBP6623_RS12855	COG0670	Belongs to the BI1 family
CFBP6623_RS12870	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFBP6623_RS12875	COG4133	protoheme IX ABC transporter activity
CFBP6623_RS12885	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP6623_RS12890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP6623_RS12915	COG2917	probably involved in intracellular septation
CFBP6623_RS12920	COG0552	protein localization to endoplasmic reticulum
CFBP6623_RS12925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP6623_RS12930	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFBP6623_RS12945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFBP6623_RS12950	COG0287	Prephenate dehydrogenase
CFBP6623_RS12950	COG1605	Chorismate mutase
CFBP6623_RS12955	COG0228	four-way junction DNA binding
CFBP6623_RS12960	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFBP6623_RS12965	COG0336	Belongs to the RNA methyltransferase TrmD family
CFBP6623_RS12975	COG0335	large ribosomal subunit rRNA binding
CFBP6623_RS12985	COG0765	amino acid transport
CFBP6623_RS13000	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFBP6623_RS13015	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFBP6623_RS13035	COG0488	(ABC) transporter
CFBP6623_RS13045	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CFBP6623_RS13055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFBP6623_RS13060	COG0142	geranyltranstransferase activity
CFBP6623_RS13065	COG2885	chlorophyll binding
CFBP6623_RS13070	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFBP6623_RS13075	COG2223	nitrite transmembrane transporter activity
CFBP6623_RS13080	COG1349	DNA-binding transcription factor activity
CFBP6623_RS13085	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFBP6623_RS13090	COG2197	response regulator
CFBP6623_RS13095	COG1132	(ABC) transporter
CFBP6623_RS13105	COG3459	Glycosyltransferase 36 associated
CFBP6623_RS13110	COG1473	amidohydrolase
CFBP6623_RS13120	COG0579	oxidoreductase
CFBP6623_RS13130	COG0129	dihydroxy-acid dehydratase activity
CFBP6623_RS13135	COG2084	Dehydrogenase
CFBP6623_RS13140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6623_RS13145	COG0277	FAD linked oxidase domain protein
CFBP6623_RS13150	COG2186	Transcriptional regulator
CFBP6623_RS13160	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP6623_RS13165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6623_RS13170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6623_RS13175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP6623_RS13185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFBP6623_RS13190	COG0495	leucyl-tRNA aminoacylation
CFBP6623_RS13205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFBP6623_RS13210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFBP6623_RS13225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP6623_RS13230	COG1946	Acyl-CoA thioesterase
CFBP6623_RS13235	COG0347	Belongs to the P(II) protein family
CFBP6623_RS13240	COG0004	ammonium transporteR
CFBP6623_RS13245	COG1674	ftsk spoiiie
CFBP6623_RS13250	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CFBP6623_RS13265	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS13275	COG1329	Transcriptional regulator
CFBP6623_RS13280	COG2902	Dehydrogenase
CFBP6623_RS13285	COG2270	Major facilitator Superfamily
CFBP6623_RS13295	COG0183	Belongs to the thiolase family
CFBP6623_RS13300	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS13315	COG0494	nUDIX hydrolase
CFBP6623_RS13325	COG0793	Belongs to the peptidase S41A family
CFBP6623_RS13335	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFBP6623_RS13340	COG0799	negative regulation of ribosome biogenesis
CFBP6623_RS13345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFBP6623_RS13350	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFBP6623_RS13355	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFBP6623_RS13360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFBP6623_RS13375	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFBP6623_RS13380	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFBP6623_RS13405	COG0066	3-isopropylmalate dehydratase activity
CFBP6623_RS13410	COG0473	3-isopropylmalate dehydrogenase activity
CFBP6623_RS13415	COG1858	cytochrome C peroxidase
CFBP6623_RS13420	COG1797	cobyrinic acid a,c-diamide synthase activity
CFBP6623_RS13425	COG1648	precorrin-2 dehydrogenase activity
CFBP6623_RS13425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP6623_RS13430	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CFBP6623_RS13495	COG1492	cobalamin metabolic process
CFBP6623_RS13510	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6623_RS13515	COG3254	rhamnose metabolic process
CFBP6623_RS13525	COG1063	alcohol dehydrogenase
CFBP6623_RS13545	COG4214	carbohydrate transport
CFBP6623_RS13550	COG1129	ABC transporter
CFBP6623_RS13555	COG2186	Transcriptional regulator
CFBP6623_RS13560	COG2721	sulfolactate sulfo-lyase activity
CFBP6623_RS13565	COG0138	bifunctional purine biosynthesis protein purh
CFBP6623_RS13575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFBP6623_RS13575	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFBP6623_RS13580	COG0501	Belongs to the peptidase M48B family
CFBP6623_RS13600	COG0357	Ribosomal RNA small subunit methyltransferase G
CFBP6623_RS13605	COG0445	tRNA wobble uridine modification
CFBP6623_RS13610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFBP6623_RS13615	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFBP6623_RS13620	COG1981	membrane
CFBP6623_RS13625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFBP6623_RS13630	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CFBP6623_RS13635	COG0424	maF-like protein
CFBP6623_RS13640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP6623_RS13645	COG0237	dephospho-CoA kinase activity
CFBP6623_RS13655	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CFBP6623_RS13660	COG3030	protein affecting phage T7 exclusion by the F plasmid
CFBP6623_RS13670	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CFBP6623_RS13695	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFBP6623_RS13710	COG0135	phosphoribosylanthranilate isomerase activity
CFBP6623_RS13715	COG0133	tryptophan synthase activity
CFBP6623_RS13720	COG0159	tryptophan synthase activity
CFBP6623_RS13725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFBP6623_RS13730	COG0285	dihydrofolate synthase activity
CFBP6623_RS13740	COG1074	ATP-dependent DNA helicase activity
CFBP6623_RS13750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFBP6623_RS13760	COG2205	protein histidine kinase activity
CFBP6623_RS13770	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CFBP6623_RS13775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP6623_RS13780	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFBP6623_RS13780	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP6623_RS13785	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFBP6623_RS13790	COG0642	Histidine kinase
CFBP6623_RS13795	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS13800	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CFBP6623_RS13810	COG1652	LysM domain
CFBP6623_RS13815	COG1072	(Pantothenic acid kinase))
CFBP6623_RS13820	COG0140	phosphoribosyl-ATP diphosphatase activity
CFBP6623_RS13825	COG0107	imidazoleglycerol-phosphate synthase activity
CFBP6623_RS13830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFBP6623_RS13835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFBP6623_RS13845	COG0131	Imidazoleglycerol-phosphate dehydratase
CFBP6623_RS13850	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFBP6623_RS13855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFBP6623_RS13865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFBP6623_RS13880	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CFBP6623_RS13890	COG1643	Atp-dependent helicase
CFBP6623_RS13935	COG0514	ATP-dependent DNA helicase (RecQ)
CFBP6623_RS13960	COG1072	(Pantothenic acid kinase))
CFBP6623_RS13970	COG1780	Probably involved in ribonucleotide reductase function
CFBP6623_RS13980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFBP6623_RS13990	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFBP6623_RS14020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6623_RS14030	COG2813	Specifically methylates the guanine in position
CFBP6623_RS14035	COG1185	polyribonucleotide nucleotidyltransferase activity
CFBP6623_RS14040	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFBP6623_RS14045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFBP6623_RS14050	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFBP6623_RS14055	COG3064	Membrane
CFBP6623_RS14055	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFBP6623_RS14070	COG0779	Required for maturation of 30S ribosomal subunits
CFBP6623_RS14075	COG2814	Major facilitator Superfamily
CFBP6623_RS14080	COG2951	lytic endotransglycosylase activity
CFBP6623_RS14085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFBP6623_RS14095	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFBP6623_RS14100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFBP6623_RS14115	COG2816	NAD+ diphosphatase activity
CFBP6623_RS14120	COG1605	Chorismate mutase
CFBP6623_RS14120	COG0077	Prephenate dehydratase
CFBP6623_RS14125	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CFBP6623_RS14130	COG3474	cytochrome
CFBP6623_RS14140	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP6623_RS14145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFBP6623_RS14155	COG1278	Cold shock
CFBP6623_RS14160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP6623_RS14170	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP6623_RS14170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP6623_RS14180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CFBP6623_RS14215	COG2900	Belongs to the SlyX family
CFBP6623_RS14225	COG0484	heat shock protein binding
CFBP6623_RS14230	COG0443	Heat shock 70 kDa protein
CFBP6623_RS14245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP6623_RS14250	COG1744	ABC transporter substrate-binding protein PnrA-like
CFBP6623_RS14255	COG3845	ABC transporter
CFBP6623_RS14260	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS14265	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS14270	COG0295	cytidine deaminase activity
CFBP6623_RS14275	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFBP6623_RS14280	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFBP6623_RS14285	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CFBP6623_RS14295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFBP6623_RS14300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFBP6623_RS14305	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFBP6623_RS14315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFBP6623_RS14320	COG1845	cytochrome c oxidase, subunit III
CFBP6623_RS14325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP6623_RS14335	COG0477	Major facilitator Superfamily
CFBP6623_RS14340	COG0070	glutamate synthase
CFBP6623_RS14340	COG0069	glutamate synthase activity
CFBP6623_RS14340	COG0067	glutamate synthase
CFBP6623_RS14345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CFBP6623_RS14360	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP6623_RS14370	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP6623_RS14405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6623_RS14425	COG0848	biopolymer transport protein
CFBP6623_RS14435	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP6623_RS14450	COG4977	sequence-specific DNA binding
CFBP6623_RS14455	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP6623_RS14460	COG3454	Phosphonate metabolism
CFBP6623_RS14465	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP6623_RS14470	COG3639	organic phosphonate transmembrane transporter activity
CFBP6623_RS14475	COG3639	organic phosphonate transmembrane transporter activity
CFBP6623_RS14480	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CFBP6623_RS14485	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFBP6623_RS14495	COG4778	phosphonate C-P lyase system protein PhnL
CFBP6623_RS14500	COG4107	phosphonate C-P lyase system protein PhnK
CFBP6623_RS14505	COG3627	carbon phosphorus lyase activity
CFBP6623_RS14510	COG3626	phosphonate metabolism
CFBP6623_RS14515	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CFBP6623_RS14520	COG3624	Phosphonate C-P lyase system protein PhnG
CFBP6623_RS14525	COG2188	Transcriptional regulator
CFBP6623_RS14530	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFBP6623_RS14535	COG0837	glucose binding
CFBP6623_RS14540	COG1803	Methylglyoxal synthase
CFBP6623_RS14545	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CFBP6623_RS14550	COG4166	transmembrane transport
CFBP6623_RS14555	COG4174	ABC transporter (Permease)
CFBP6623_RS14560	COG4239	(ABC) transporter, permease
CFBP6623_RS14565	COG4172	Belongs to the ABC transporter superfamily
CFBP6623_RS14570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS14575	COG0174	glutamine synthetase
CFBP6623_RS14580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS14585	COG3265	gluconokinase activity
CFBP6623_RS14590	COG1174	glycine betaine transport
CFBP6623_RS14595	COG1125	glycine betaine transport
CFBP6623_RS14600	COG1174	glycine betaine transport
CFBP6623_RS14605	COG1732	Glycine betaine
CFBP6623_RS14615	COG1959	2 iron, 2 sulfur cluster binding
CFBP6623_RS14620	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6623_RS14630	COG4269	membrane
CFBP6623_RS14650	COG0697	spore germination
CFBP6623_RS14675	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFBP6623_RS14680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP6623_RS14715	COG4964	Belongs to the GSP D family
CFBP6623_RS14765	COG3422	double-strand break repair
CFBP6623_RS14770	COG3757	hydrolase, family 25
CFBP6623_RS14775	COG0697	spore germination
CFBP6623_RS14780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6623_RS14810	COG0481	GTPase activity
CFBP6623_RS14815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP6623_RS14845	COG2169	Transcriptional regulator
CFBP6623_RS14845	COG1917	Cupin 2, conserved barrel domain protein
CFBP6623_RS14850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP6623_RS14875	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFBP6623_RS14880	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFBP6623_RS14885	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFBP6623_RS14895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFBP6623_RS14900	COG0072	phenylalanine-tRNA ligase activity
CFBP6623_RS14900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP6623_RS14905	COG0667	Aldo Keto reductase
CFBP6623_RS14925	COG4977	sequence-specific DNA binding
CFBP6623_RS14950	COG1570	exodeoxyribonuclease VII activity
CFBP6623_RS14955	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6623_RS14965	COG1846	Transcriptional regulator
CFBP6623_RS14970	COG0697	spore germination
CFBP6623_RS14975	COG2309	aminopeptidase activity
CFBP6623_RS14985	COG1393	Belongs to the ArsC family
CFBP6623_RS15005	COG1309	transcriptional regulator
CFBP6623_RS15015	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFBP6623_RS15015	COG0519	Catalyzes the synthesis of GMP from XMP
CFBP6623_RS15030	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CFBP6623_RS15060	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CFBP6623_RS15070	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFBP6623_RS15080	COG1968	undecaprenyl-diphosphatase activity
CFBP6623_RS15105	COG0284	orotidine-5'-phosphate decarboxylase activity
CFBP6623_RS15115	COG3963	phosphatidate phosphatase activity
CFBP6623_RS15125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFBP6623_RS15130	COG0792	nuclease activity
CFBP6623_RS15145	COG1175	transmembrane transport
CFBP6623_RS15155	COG3842	ATPase activity
CFBP6623_RS15165	COG0189	ligase activity
CFBP6623_RS15175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFBP6623_RS15180	COG1280	lysine exporter protein (LysE YggA)
CFBP6623_RS15185	COG0756	dUTP diphosphatase activity
CFBP6623_RS15190	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFBP6623_RS15195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFBP6623_RS15210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFBP6623_RS15215	COG2226	methyltransferase
CFBP6623_RS15220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFBP6623_RS15225	COG1024	Enoyl-CoA hydratase
CFBP6623_RS15230	COG0268	Binds directly to 16S ribosomal RNA
CFBP6623_RS15265	COG0640	Transcriptional regulator
CFBP6623_RS15300	COG3842	ATPase activity
CFBP6623_RS15305	COG1175	transmembrane transport
CFBP6623_RS15330	COG1049	propionate catabolic process, 2-methylcitrate cycle
CFBP6623_RS15335	COG0840	transmembrane signaling receptor activity
CFBP6623_RS15370	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS15375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP6623_RS15385	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6623_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS15395	COG1414	Transcriptional regulator
CFBP6623_RS15400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFBP6623_RS15405	COG3842	ATPase activity
CFBP6623_RS15410	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS15415	COG1175	transmembrane transport
CFBP6623_RS15425	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6623_RS15430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6623_RS15435	COG3734	2-keto-3-deoxy-galactonokinase
CFBP6623_RS15440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6623_RS15455	COG2828	Protein conserved in bacteria
CFBP6623_RS15460	COG0583	DNA-binding transcription factor activity
CFBP6623_RS15465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFBP6623_RS15470	COG0583	DNA-binding transcription factor activity
CFBP6623_RS15475	COG2233	PERMEase
CFBP6623_RS15480	COG5001	Diguanylate cyclase
CFBP6623_RS15550	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CFBP6623_RS15580	COG1653	transport
CFBP6623_RS15585	COG1175	transmembrane transport
CFBP6623_RS15590	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS15595	COG3842	ATPase activity
CFBP6623_RS15600	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS15605	COG1175	transmembrane transport
CFBP6623_RS15635	COG1609	Transcriptional regulator
CFBP6623_RS15645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6623_RS15650	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6623_RS15665	COG3842	ATPase activity
CFBP6623_RS15670	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS15675	COG1175	transmembrane transport
CFBP6623_RS15680	COG1653	transport
CFBP6623_RS15685	COG1309	transcriptional regulator
CFBP6623_RS15690	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS15705	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS15710	COG1278	Cold shock
CFBP6623_RS15720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP6623_RS15745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6623_RS15760	COG1629	transport
CFBP6623_RS15765	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFBP6623_RS15770	COG3618	amidohydrolase
CFBP6623_RS15775	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6623_RS15780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6623_RS15785	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS15790	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CFBP6623_RS15795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6623_RS15800	COG2186	Transcriptional regulator
CFBP6623_RS15845	COG4977	sequence-specific DNA binding
CFBP6623_RS15850	COG2223	nitrite transmembrane transporter activity
CFBP6623_RS15855	COG0583	DNA-binding transcription factor activity
CFBP6623_RS15860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6623_RS15870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6623_RS15875	COG2084	Dehydrogenase
CFBP6623_RS15890	COG1609	Transcriptional regulator
CFBP6623_RS15895	COG1063	alcohol dehydrogenase
CFBP6623_RS15900	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS15910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6623_RS15915	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CFBP6623_RS15920	COG1175	transmembrane transport
CFBP6623_RS15925	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS15940	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS15945	COG1175	transmembrane transport
CFBP6623_RS15950	COG2182	Extracellular solute-binding protein
CFBP6623_RS15955	COG0626	cystathionine gamma-synthase activity
CFBP6623_RS15965	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFBP6623_RS15975	COG1121	(ABC) transporter
CFBP6623_RS15980	COG0523	cobalamin synthesis protein
CFBP6623_RS15995	COG2226	methyltransferase
CFBP6623_RS16000	COG0587	DNA-directed DNA polymerase activity
CFBP6623_RS16030	COG5001	Diguanylate cyclase
CFBP6623_RS16030	COG3300	MHYT domain
CFBP6623_RS16040	COG2011	ABC-type metal ion transport system permease component
CFBP6623_RS16045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFBP6623_RS16050	COG0778	Nitroreductase
CFBP6623_RS16090	COG0583	DNA-binding transcription factor activity
CFBP6623_RS16095	COG1879	ABC-type sugar transport system periplasmic component
CFBP6623_RS16100	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS16105	COG1129	ABC transporter
CFBP6623_RS16115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6623_RS16120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6623_RS16125	COG3447	MASE1 domain protein
CFBP6623_RS16125	COG5002	protein histidine kinase activity
CFBP6623_RS16125	COG5001	Diguanylate cyclase
CFBP6623_RS16130	COG3257	ureidoglycine aminohydrolase activity
CFBP6623_RS16140	COG5001	Diguanylate cyclase
CFBP6623_RS16145	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP6623_RS16155	COG0747	negative chemotaxis
CFBP6623_RS16160	COG0601	transmembrane transport
CFBP6623_RS16165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS16170	COG0444	Belongs to the ABC transporter superfamily
CFBP6623_RS16175	COG4608	Belongs to the ABC transporter superfamily
CFBP6623_RS16195	COG0346	lactoylglutathione lyase activity
CFBP6623_RS16205	COG0129	dihydroxy-acid dehydratase activity
CFBP6623_RS16210	COG1879	ABC-type sugar transport system periplasmic component
CFBP6623_RS16220	COG1129	ABC transporter
CFBP6623_RS16225	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS16230	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS16235	COG2186	Transcriptional regulator
CFBP6623_RS16250	COG0523	cobalamin synthesis protein
CFBP6623_RS16255	COG1653	transport
CFBP6623_RS16260	COG1175	transmembrane transport
CFBP6623_RS16265	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS16270	COG3842	ATPase activity
CFBP6623_RS16280	COG3047	cAMP biosynthetic process
CFBP6623_RS16285	COG2115	Belongs to the xylose isomerase family
CFBP6623_RS16290	COG1070	Carbohydrate kinase
CFBP6623_RS16295	COG1609	Transcriptional regulator
CFBP6623_RS16310	COG1309	transcriptional regulator
CFBP6623_RS16315	COG1253	flavin adenine dinucleotide binding
CFBP6623_RS16320	COG3273	potassium ion transport
CFBP6623_RS16320	COG0471	metal ion transport
CFBP6623_RS16325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP6623_RS16335	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFBP6623_RS16345	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFBP6623_RS16350	COG1121	(ABC) transporter
CFBP6623_RS16355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP6623_RS16360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP6623_RS16370	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS16375	COG1414	Transcriptional regulator
CFBP6623_RS16380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFBP6623_RS16390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP6623_RS16395	COG2186	Transcriptional regulator
CFBP6623_RS16400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6623_RS16410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6623_RS16415	COG1063	alcohol dehydrogenase
CFBP6623_RS16420	COG1312	Catalyzes the dehydration of D-mannonate
CFBP6623_RS16440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6623_RS16445	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP6623_RS16445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6623_RS16450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS16465	COG0625	glutathione transferase activity
CFBP6623_RS16470	COG4172	Belongs to the ABC transporter superfamily
CFBP6623_RS16475	COG1921	L-seryl-tRNASec selenium transferase activity
CFBP6623_RS16490	COG3964	amidohydrolase
CFBP6623_RS16500	COG0601	transmembrane transport
CFBP6623_RS16505	COG0747	negative chemotaxis
CFBP6623_RS16510	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP6623_RS16515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6623_RS16545	COG4989	oxidoreductase activity
CFBP6623_RS16560	COG3842	ATPase activity
CFBP6623_RS16565	COG1653	transport
CFBP6623_RS16570	COG1175	transmembrane transport
CFBP6623_RS16575	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS16580	COG1501	Belongs to the glycosyl hydrolase 31 family
CFBP6623_RS16620	COG4372	Transposase
CFBP6623_RS16625	COG3436	PFAM IS66 Orf2 family protein
CFBP6623_RS16630	COG2963	transposase activity
CFBP6623_RS16675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6623_RS16680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6623_RS16685	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CFBP6623_RS16690	COG0352	thiamine-phosphate diphosphorylase activity
CFBP6623_RS16695	COG0351	phosphomethylpyrimidine kinase
CFBP6623_RS16705	COG1522	sequence-specific DNA binding
CFBP6623_RS16710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP6623_RS16715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS16730	COG2204	response regulator
CFBP6623_RS16735	COG4191	Histidine kinase
CFBP6623_RS16740	COG1301	dicarboxylic acid transport
CFBP6623_RS16750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6623_RS16755	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS16765	COG1473	amidohydrolase
CFBP6623_RS16785	COG1215	transferase activity, transferring glycosyl groups
CFBP6623_RS16795	COG2942	2-epimerase
CFBP6623_RS16815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFBP6623_RS16820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6623_RS16860	COG3307	-O-antigen
CFBP6623_RS16865	COG1596	polysaccharide export
CFBP6623_RS16870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFBP6623_RS16880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6623_RS16885	COG0840	transmembrane signaling receptor activity
CFBP6623_RS16890	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6623_RS16900	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS16910	COG2094	Belongs to the DNA glycosylase MPG family
CFBP6623_RS16925	COG1609	Transcriptional regulator
CFBP6623_RS16930	COG1653	transport
CFBP6623_RS16955	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS16960	COG0602	queuosine metabolic process
CFBP6623_RS16965	COG0720	synthase
CFBP6623_RS16970	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFBP6623_RS16975	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS16990	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS16995	COG1175	transmembrane transport
CFBP6623_RS17010	COG0281	malic enzyme
CFBP6623_RS17010	COG0280	phosphate acetyltransferase
CFBP6623_RS17025	COG0765	amino acid transport
CFBP6623_RS17030	COG1126	abc transporter atp-binding protein
CFBP6623_RS17035	COG2079	MmgE PrpD family protein
CFBP6623_RS17040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS17050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS17075	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP6623_RS17080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFBP6623_RS17085	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS17090	COG1129	ABC transporter
CFBP6623_RS17105	COG1473	amidohydrolase
CFBP6623_RS17130	COG0601	transmembrane transport
CFBP6623_RS17135	COG0583	DNA-binding transcription factor activity
CFBP6623_RS17140	COG1446	asparaginase
CFBP6623_RS17155	COG0747	negative chemotaxis
CFBP6623_RS17175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS17180	COG0601	transmembrane transport
CFBP6623_RS17185	COG2197	response regulator
CFBP6623_RS17190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP6623_RS17195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6623_RS17210	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS17215	COG1175	transmembrane transport
CFBP6623_RS17225	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS17230	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS17250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6623_RS17255	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP6623_RS17275	COG1595	DNA-templated transcription, initiation
CFBP6623_RS17280	COG1120	ATPase activity
CFBP6623_RS17285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6623_RS17300	COG2226	methyltransferase
CFBP6623_RS17310	COG1120	ATPase activity
CFBP6623_RS17315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6623_RS17330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP6623_RS17335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP6623_RS17345	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS17350	COG0473	3-isopropylmalate dehydrogenase activity
CFBP6623_RS17355	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS17360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS17395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS17405	COG1522	sequence-specific DNA binding
CFBP6623_RS17410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS17420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6623_RS17425	COG1126	abc transporter atp-binding protein
CFBP6623_RS17435	COG1473	amidohydrolase
CFBP6623_RS17440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS17445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS17450	COG1959	2 iron, 2 sulfur cluster binding
CFBP6623_RS17460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP6623_RS17495	COG1960	acyl-CoA dehydrogenase activity
CFBP6623_RS17530	COG0667	Aldo Keto reductase
CFBP6623_RS17540	COG0583	DNA-binding transcription factor activity
CFBP6623_RS17545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS17560	COG0747	negative chemotaxis
CFBP6623_RS17565	COG1473	amidohydrolase
CFBP6623_RS17570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS17590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS17595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS17615	COG4608	Belongs to the ABC transporter superfamily
CFBP6623_RS17620	COG0444	Belongs to the ABC transporter superfamily
CFBP6623_RS17630	COG0601	transmembrane transport
CFBP6623_RS17640	COG2186	Transcriptional regulator
CFBP6623_RS17645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6623_RS17645	COG3453	Protein conserved in bacteria
CFBP6623_RS17650	COG0640	Transcriptional regulator
CFBP6623_RS17660	COG2391	methyltransferase activity
CFBP6623_RS17665	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFBP6623_RS17680	COG0022	dehydrogenase e1 component
CFBP6623_RS17690	COG1960	acyl-CoA dehydrogenase activity
CFBP6623_RS17695	COG0183	Belongs to the thiolase family
CFBP6623_RS17705	COG1960	acyl-CoA dehydrogenase activity
CFBP6623_RS17710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP6623_RS17725	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CFBP6623_RS17730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFBP6623_RS17735	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CFBP6623_RS17740	COG4952	isomerase
CFBP6623_RS17745	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS17745	COG3347	Dehydrogenase
CFBP6623_RS17750	COG1349	DNA-binding transcription factor activity
CFBP6623_RS17765	COG1129	ABC transporter
CFBP6623_RS17770	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS17780	COG3254	rhamnose metabolic process
CFBP6623_RS17795	COG2264	protein methyltransferase activity
CFBP6623_RS17800	COG5001	Diguanylate cyclase
CFBP6623_RS17820	COG4335	DNA alkylation repair
CFBP6623_RS17825	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP6623_RS17830	COG4208	sulfate ABC transporter
CFBP6623_RS17845	COG1024	Enoyl-CoA hydratase
CFBP6623_RS17860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP6623_RS17875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP6623_RS17885	COG1040	competence protein
CFBP6623_RS17890	COG2226	methyltransferase
CFBP6623_RS17905	COG0494	nUDIX hydrolase
CFBP6623_RS17915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFBP6623_RS17920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFBP6623_RS17925	COG0653	protein targeting
CFBP6623_RS17930	COG0697	spore germination
CFBP6623_RS17995	COG0489	protein tyrosine kinase activity
CFBP6623_RS17995	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP6623_RS18040	COG0438	transferase activity, transferring glycosyl groups
CFBP6623_RS18050	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CFBP6623_RS18055	COG1088	dTDP-glucose 4,6-dehydratase activity
CFBP6623_RS18060	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFBP6623_RS18065	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFBP6623_RS18070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFBP6623_RS18075	COG2273	Hydrolase Family 16
CFBP6623_RS18075	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CFBP6623_RS18090	COG3842	ATPase activity
CFBP6623_RS18095	COG3833	ABC-type maltose transport systems, permease component
CFBP6623_RS18150	COG1396	sequence-specific DNA binding
CFBP6623_RS18160	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFBP6623_RS18165	COG1129	ABC transporter
CFBP6623_RS18170	COG4214	carbohydrate transport
CFBP6623_RS18175	COG4213	ABC transporter substrate-binding protein
CFBP6623_RS18190	COG0346	lactoylglutathione lyase activity
CFBP6623_RS18195	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFBP6623_RS18195	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFBP6623_RS18200	COG4770	biotin carboxylase activity
CFBP6623_RS18210	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CFBP6623_RS18220	COG0625	glutathione transferase activity
CFBP6623_RS18225	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP6623_RS18230	COG3800	Transcriptional regulator
CFBP6623_RS18230	COG1396	sequence-specific DNA binding
CFBP6623_RS18240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP6623_RS18250	COG0300	oxidoreductase activity
CFBP6623_RS18260	COG2096	Adenosyltransferase
CFBP6623_RS18270	COG2086	electron transfer activity
CFBP6623_RS18280	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP6623_RS18285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFBP6623_RS18290	COG0165	Argininosuccinate lyase
CFBP6623_RS18300	COG0019	diaminopimelate decarboxylase activity
CFBP6623_RS18325	COG2884	Cell division ATP-binding protein ftsE
CFBP6623_RS18345	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CFBP6623_RS18360	COG0287	Prephenate dehydrogenase
CFBP6623_RS18365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP6623_RS18370	COG2226	methyltransferase
CFBP6623_RS18375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6623_RS18390	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFBP6623_RS18395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFBP6623_RS18430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFBP6623_RS18435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFBP6623_RS18450	COG4974	Belongs to the 'phage' integrase family
CFBP6623_RS18455	COG0825	malonyl-CoA metabolic process
CFBP6623_RS18460	COG3034	peptidoglycan biosynthetic process
CFBP6623_RS18465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFBP6623_RS18465	COG0425	Belongs to the sulfur carrier protein TusA family
CFBP6623_RS18475	COG0523	cobalamin synthesis protein
CFBP6623_RS18480	COG1686	Belongs to the peptidase S11 family
CFBP6623_RS18485	COG1473	amidohydrolase
CFBP6623_RS18530	COG0667	Aldo Keto reductase
CFBP6623_RS18535	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS18545	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS18555	COG3962	Belongs to the TPP enzyme family
CFBP6623_RS18560	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS18565	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS18575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP6623_RS18595	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS18600	COG1129	ABC transporter
CFBP6623_RS18610	COG4953	penicillin-binding protein 1C
CFBP6623_RS18615	COG2373	Large extracellular alpha-helical protein
CFBP6623_RS18620	COG2835	tetraacyldisaccharide 4'-kinase activity
CFBP6623_RS18630	COG3118	belongs to the thioredoxin family
CFBP6623_RS18650	COG0482	sulfurtransferase activity
CFBP6623_RS18665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP6623_RS18680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP6623_RS18685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP6623_RS18690	COG0037	tRNA processing
CFBP6623_RS18700	COG2885	chlorophyll binding
CFBP6623_RS18705	COG0823	Involved in the tonB-independent uptake of proteins
CFBP6623_RS18725	COG0824	Thioesterase
CFBP6623_RS18735	COG0494	nUDIX hydrolase
CFBP6623_RS18745	COG1408	metallophosphoesterase
CFBP6623_RS18750	COG2255	four-way junction helicase activity
CFBP6623_RS18755	COG0632	four-way junction helicase activity
CFBP6623_RS18760	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CFBP6623_RS18765	COG0840	transmembrane signaling receptor activity
CFBP6623_RS18770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS18775	COG0217	transcriptional regulatory protein
CFBP6623_RS18790	COG1692	metallophosphoesterase
CFBP6623_RS18800	COG1253	flavin adenine dinucleotide binding
CFBP6623_RS18845	COG0126	phosphoglycerate kinase activity
CFBP6623_RS18850	COG3588	fructose-bisphosphate aldolase
CFBP6623_RS18870	COG0254	rRNA binding
CFBP6623_RS18875	COG1132	(ABC) transporter
CFBP6623_RS18895	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6623_RS18925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFBP6623_RS18930	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFBP6623_RS18935	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFBP6623_RS18940	COG0457	Tetratricopeptide repeat
CFBP6623_RS18945	COG3750	Belongs to the UPF0335 family
CFBP6623_RS18965	COG0469	pyruvate kinase activity
CFBP6623_RS18970	COG3108	Peptidase M15
CFBP6623_RS18975	COG2204	response regulator
CFBP6623_RS18980	COG1164	Oligoendopeptidase f
CFBP6623_RS18985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP6623_RS18995	COG5310	Homospermidine synthase
CFBP6623_RS19005	COG0737	Belongs to the 5'-nucleotidase family
CFBP6623_RS19010	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CFBP6623_RS19015	COG0330	HflC and HflK could
CFBP6623_RS19045	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP6623_RS19050	COG2951	lytic endotransglycosylase activity
CFBP6623_RS19065	COG2205	protein histidine kinase activity
CFBP6623_RS19075	COG0067	glutamate synthase
CFBP6623_RS19075	COG0069	glutamate synthase activity
CFBP6623_RS19075	COG0070	glutamate synthase
CFBP6623_RS19090	COG2205	protein histidine kinase activity
CFBP6623_RS19095	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CFBP6623_RS19100	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CFBP6623_RS19105	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CFBP6623_RS19115	COG0252	asparaginase activity
CFBP6623_RS19125	COG1027	Aspartate ammonia-lyase
CFBP6623_RS19130	COG2186	Transcriptional regulator
CFBP6623_RS19135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6623_RS19145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6623_RS19150	COG1309	transcriptional regulator
CFBP6623_RS19160	COG3842	ATPase activity
CFBP6623_RS19165	COG1177	transmembrane transport
CFBP6623_RS19185	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS19190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS19200	COG2267	carboxylic ester hydrolase activity
CFBP6623_RS19215	COG1126	abc transporter atp-binding protein
CFBP6623_RS19220	COG0765	amino acid transport
CFBP6623_RS19240	COG0174	glutamine synthetase
CFBP6623_RS19245	COG0069	glutamate synthase activity
CFBP6623_RS19250	COG2218	PFAM glutamate synthase alpha subunit domain protein
CFBP6623_RS19255	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFBP6623_RS19265	COG4977	sequence-specific DNA binding
CFBP6623_RS19270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS19275	COG4311	Sarcosine oxidase, delta subunit
CFBP6623_RS19280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP6623_RS19280	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP6623_RS19290	COG1609	Transcriptional regulator
CFBP6623_RS19310	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6623_RS19315	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS19320	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6623_RS19325	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6623_RS19330	COG2957	Belongs to the agmatine deiminase family
CFBP6623_RS19345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6623_RS19355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS19360	COG0601	transmembrane transport
CFBP6623_RS19365	COG0747	negative chemotaxis
CFBP6623_RS19375	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP6623_RS19380	COG1454	alcohol dehydrogenase
CFBP6623_RS19425	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP6623_RS19425	COG2307	Protein conserved in bacteria
CFBP6623_RS19440	COG0488	(ABC) transporter
CFBP6623_RS19445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6623_RS19450	COG1304	FMN binding
CFBP6623_RS19485	COG0765	amino acid transport
CFBP6623_RS19490	COG0765	amino acid transport
CFBP6623_RS19500	COG1063	alcohol dehydrogenase
CFBP6623_RS19505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP6623_RS19510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6623_RS19520	COG0765	amino acid transport
CFBP6623_RS19525	COG0765	amino acid transport
CFBP6623_RS19530	COG4221	oxidoreductase activity
CFBP6623_RS19535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6623_RS19540	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS19545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6623_RS19560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP6623_RS19575	COG0697	spore germination
CFBP6623_RS19580	COG0697	spore germination
CFBP6623_RS19585	COG0511	ligase activity, forming carbon-carbon bonds
CFBP6623_RS19590	COG0439	Biotin carboxylase
CFBP6623_RS19600	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP6623_RS19605	COG1984	allophanate hydrolase subunit 2
CFBP6623_RS19610	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP6623_RS19615	COG3842	ATPase activity
CFBP6623_RS19625	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP6623_RS19635	COG0436	Aminotransferase
CFBP6623_RS19650	COG1070	Carbohydrate kinase
CFBP6623_RS19655	COG1830	Aldolase
CFBP6623_RS19660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFBP6623_RS19665	COG0667	Aldo Keto reductase
CFBP6623_RS19675	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS19680	COG1129	ABC transporter
CFBP6623_RS19685	COG1879	ABC-type sugar transport system periplasmic component
CFBP6623_RS19715	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6623_RS19730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP6623_RS19745	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS19755	COG3842	ATPase activity
CFBP6623_RS19760	COG3842	ATPase activity
CFBP6623_RS19775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP6623_RS19775	COG1648	precorrin-2 dehydrogenase activity
CFBP6623_RS19780	COG0243	molybdopterin cofactor binding
CFBP6623_RS19795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFBP6623_RS19800	COG1116	anion transmembrane transporter activity
CFBP6623_RS19805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6623_RS19810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6623_RS19820	COG3707	response regulator
CFBP6623_RS19825	COG1802	Transcriptional regulator
CFBP6623_RS19830	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP6623_RS19835	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP6623_RS19840	COG4336	lyase activity
CFBP6623_RS19845	COG1984	allophanate hydrolase subunit 2
CFBP6623_RS19850	COG4770	biotin carboxylase activity
CFBP6623_RS19855	COG0366	Alpha amylase catalytic
CFBP6623_RS19865	COG4771	TonB-dependent receptor
CFBP6623_RS19870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFBP6623_RS19890	COG1414	Transcriptional regulator
CFBP6623_RS19895	COG1475	DNA binding
CFBP6623_RS19900	COG1192	Involved in chromosome partitioning
CFBP6623_RS19930	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFBP6623_RS19940	COG2986	histidine ammonia-lyase
CFBP6623_RS19945	COG1228	amidohydrolase
CFBP6623_RS19950	COG0402	S-adenosylhomocysteine deaminase activity
CFBP6623_RS20000	COG0596	Alpha beta hydrolase
CFBP6623_RS20030	COG1454	alcohol dehydrogenase
CFBP6623_RS20065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP6623_RS20085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP6623_RS20090	COG0328	RNA-DNA hybrid ribonuclease activity
CFBP6623_RS20110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6623_RS20115	COG4172	Belongs to the ABC transporter superfamily
CFBP6623_RS20120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS20125	COG0601	transmembrane transport
CFBP6623_RS20130	COG4166	transmembrane transport
CFBP6623_RS20135	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS20160	COG2205	protein histidine kinase activity
CFBP6623_RS20165	COG1802	Transcriptional regulator
CFBP6623_RS20170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6623_RS20175	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS20190	COG3448	diguanylate cyclase activity
CFBP6623_RS20190	COG4175	Glycine betaine
CFBP6623_RS20195	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP6623_RS20200	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP6623_RS20205	COG3938	Belongs to the proline racemase family
CFBP6623_RS20215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFBP6623_RS20260	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP6623_RS20265	COG0517	IMP dehydrogenase activity
CFBP6623_RS20265	COG4175	Glycine betaine
CFBP6623_RS20270	COG2986	histidine ammonia-lyase
CFBP6623_RS20275	COG0583	DNA-binding transcription factor activity
CFBP6623_RS20280	COG0346	lactoylglutathione lyase activity
CFBP6623_RS20295	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CFBP6623_RS20305	COG2814	Major facilitator Superfamily
CFBP6623_RS20315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6623_RS20320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6623_RS20355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFBP6623_RS20360	COG0356	it plays a direct role in the translocation of protons across the membrane
CFBP6623_RS20370	COG0387	Pfam Sodium calcium exchanger
CFBP6623_RS20375	COG2268	Band 7 protein
CFBP6623_RS20385	COG1842	Phage shock protein A
CFBP6623_RS20395	COG0583	DNA-binding transcription factor activity
CFBP6623_RS20400	COG0477	Major facilitator Superfamily
CFBP6623_RS20440	COG2205	protein histidine kinase activity
CFBP6623_RS20445	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS20450	COG0671	phosphoesterase, PA-phosphatase related
CFBP6623_RS20470	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CFBP6623_RS20480	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CFBP6623_RS20485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6623_RS20490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFBP6623_RS20505	COG0010	Belongs to the arginase family
CFBP6623_RS20515	COG0697	spore germination
CFBP6623_RS20520	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS20545	COG0477	Major facilitator Superfamily
CFBP6623_RS20560	COG2194	sulfuric ester hydrolase activity
CFBP6623_RS20580	COG1120	ATPase activity
CFBP6623_RS20590	COG3474	cytochrome
CFBP6623_RS20595	COG2137	regulation of response to DNA damage stimulus
CFBP6623_RS20600	COG3386	PFAM SMP-30 Gluconolaconase
CFBP6623_RS20610	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS20615	COG1129	ABC transporter
CFBP6623_RS20620	COG1879	ABC-type sugar transport system periplasmic component
CFBP6623_RS20630	COG4585	Histidine kinase
CFBP6623_RS20635	COG2197	response regulator
CFBP6623_RS20645	COG2133	pyrroloquinoline quinone binding
CFBP6623_RS20655	COG0500	methyltransferase
CFBP6623_RS20660	COG0564	pseudouridine synthase activity
CFBP6623_RS20675	COG0517	IMP dehydrogenase activity
CFBP6623_RS20675	COG4175	Glycine betaine
CFBP6623_RS20680	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP6623_RS20690	COG4191	Histidine kinase
CFBP6623_RS20690	COG0784	Response regulator, receiver
CFBP6623_RS20700	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP6623_RS20700	COG0489	protein tyrosine kinase activity
CFBP6623_RS20705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP6623_RS20710	COG1215	transferase activity, transferring glycosyl groups
CFBP6623_RS20715	COG1215	transferase activity, transferring glycosyl groups
CFBP6623_RS20720	COG1215	transferase activity, transferring glycosyl groups
CFBP6623_RS20725	COG0438	transferase activity, transferring glycosyl groups
CFBP6623_RS20730	COG2273	Hydrolase Family 16
CFBP6623_RS20735	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP6623_RS20740	COG2244	polysaccharide biosynthetic process
CFBP6623_RS20745	COG0463	Glycosyl transferase, family 2
CFBP6623_RS20750	COG2327	Polysaccharide pyruvyl transferase
CFBP6623_RS20755	COG1215	transferase activity, transferring glycosyl groups
CFBP6623_RS20775	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP6623_RS20785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS20800	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP6623_RS20800	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP6623_RS20830	COG1523	belongs to the glycosyl hydrolase 13 family
CFBP6623_RS20835	COG0033	Phosphoglucomutase
CFBP6623_RS20840	COG0297	glycogen (starch) synthase activity
CFBP6623_RS20845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CFBP6623_RS20850	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFBP6623_RS20855	COG0058	SHG alpha-glucan phosphorylase activity
CFBP6623_RS20870	COG1794	racemase activity, acting on amino acids and derivatives
CFBP6623_RS20875	COG1522	sequence-specific DNA binding
CFBP6623_RS20885	COG2084	Dehydrogenase
CFBP6623_RS20890	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS20895	COG1063	alcohol dehydrogenase
CFBP6623_RS20905	COG4988	ABC transporter
CFBP6623_RS20910	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CFBP6623_RS20920	COG1294	oxidase, subunit
CFBP6623_RS20950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CFBP6623_RS20955	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFBP6623_RS20985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CFBP6623_RS20990	COG0539	negative regulation of cytoplasmic translation
CFBP6623_RS21020	COG4221	oxidoreductase activity
CFBP6623_RS21030	COG0006	proline dipeptidase activity
CFBP6623_RS21035	COG0747	negative chemotaxis
CFBP6623_RS21040	COG0601	transmembrane transport
CFBP6623_RS21045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS21050	COG0444	Belongs to the ABC transporter superfamily
CFBP6623_RS21055	COG4608	Belongs to the ABC transporter superfamily
CFBP6623_RS21060	COG0246	Mannitol dehydrogenase
CFBP6623_RS21075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS21100	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS21120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP6623_RS21125	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS21135	COG4993	Dehydrogenase
CFBP6623_RS21140	COG3685	Protein conserved in bacteria
CFBP6623_RS21145	COG1285	pathogenesis
CFBP6623_RS21170	COG0693	protein deglycase activity
CFBP6623_RS21195	COG0189	ligase activity
CFBP6623_RS21200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6623_RS21205	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFBP6623_RS21215	COG0435	Glutathione S-transferase
CFBP6623_RS21220	COG0583	DNA-binding transcription factor activity
CFBP6623_RS21225	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS21235	COG1522	sequence-specific DNA binding
CFBP6623_RS21250	COG0784	Response regulator, receiver
CFBP6623_RS21270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFBP6623_RS21285	COG0019	diaminopimelate decarboxylase activity
CFBP6623_RS21305	COG0527	aspartate kinase activity
CFBP6623_RS21315	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFBP6623_RS21320	COG2890	protein-(glutamine-N5) methyltransferase activity
CFBP6623_RS21330	COG0542	response to heat
CFBP6623_RS21335	COG0739	heme binding
CFBP6623_RS21335	COG0741	lytic transglycosylase activity
CFBP6623_RS21335	COG1196	nuclear chromosome segregation
CFBP6623_RS21385	COG0300	oxidoreductase activity
CFBP6623_RS21400	COG1741	Belongs to the pirin family
CFBP6623_RS21430	COG0642	Histidine kinase
CFBP6623_RS21435	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS21440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP6623_RS21440	COG0475	glutathione-regulated potassium exporter activity
CFBP6623_RS21460	COG1335	isochorismatase
CFBP6623_RS21480	COG1733	regulation of RNA biosynthetic process
CFBP6623_RS21495	COG1505	serine-type exopeptidase activity
CFBP6623_RS21540	COG1129	ABC transporter
CFBP6623_RS21545	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS21550	COG1879	ABC-type sugar transport system periplasmic component
CFBP6623_RS21555	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6623_RS21560	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS21565	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6623_RS21570	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS21590	COG1126	abc transporter atp-binding protein
CFBP6623_RS21595	COG0765	amino acid transport
CFBP6623_RS21600	COG0765	amino acid transport
CFBP6623_RS21605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6623_RS21615	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS21620	COG3938	Belongs to the proline racemase family
CFBP6623_RS21625	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS21630	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS21735	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP6623_RS21740	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6623_RS21755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CFBP6623_RS21770	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFBP6623_RS21780	COG2986	histidine ammonia-lyase
CFBP6623_RS21800	COG0584	glycerophosphoryl diester phosphodiesterase
CFBP6623_RS21805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS21815	COG4608	Belongs to the ABC transporter superfamily
CFBP6623_RS21820	COG0444	Belongs to the ABC transporter superfamily
CFBP6623_RS21840	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS21845	COG5002	protein histidine kinase activity
CFBP6623_RS21850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6623_RS21855	COG0577	efflux transmembrane transporter activity
CFBP6623_RS21855	COG1136	(ABC) transporter
CFBP6623_RS21865	COG1733	regulation of RNA biosynthetic process
CFBP6623_RS21875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFBP6623_RS21885	COG3842	ATPase activity
CFBP6623_RS21890	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS21895	COG1175	transmembrane transport
CFBP6623_RS21905	COG3976	FMN-binding domain protein
CFBP6623_RS21905	COG1053	succinate dehydrogenase
CFBP6623_RS21910	COG1609	Transcriptional regulator
CFBP6623_RS21915	COG1522	sequence-specific DNA binding
CFBP6623_RS21925	COG1116	anion transmembrane transporter activity
CFBP6623_RS21930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6623_RS21935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6623_RS21945	COG0405	Gamma-glutamyltransferase
CFBP6623_RS21960	COG2376	Dihydroxyacetone kinase
CFBP6623_RS21990	COG1846	Transcriptional regulator
CFBP6623_RS21995	COG4178	(ABC) transporter
CFBP6623_RS22020	COG1929	Belongs to the glycerate kinase type-1 family
CFBP6623_RS22055	COG0583	DNA-binding transcription factor activity
CFBP6623_RS22060	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6623_RS22070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6623_RS22080	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS22090	COG1653	transport
CFBP6623_RS22095	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS22100	COG4209	transmembrane transport
CFBP6623_RS22105	COG3842	ATPase activity
CFBP6623_RS22110	COG1802	Transcriptional regulator
CFBP6623_RS22120	COG1309	transcriptional regulator
CFBP6623_RS22135	COG1136	(ABC) transporter
CFBP6623_RS22150	COG1063	alcohol dehydrogenase
CFBP6623_RS22160	COG1879	ABC-type sugar transport system periplasmic component
CFBP6623_RS22170	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS22290	COG3300	MHYT domain
CFBP6623_RS22290	COG5001	Diguanylate cyclase
CFBP6623_RS22315	COG1609	Transcriptional regulator
CFBP6623_RS22320	COG1178	ABC-type Fe3 transport system permease component
CFBP6623_RS22325	COG3842	ATPase activity
CFBP6623_RS22345	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6623_RS22355	COG1253	flavin adenine dinucleotide binding
CFBP6623_RS22375	COG3842	ATPase activity
CFBP6623_RS22380	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS22385	COG1175	transmembrane transport
CFBP6623_RS22390	COG1653	transport
CFBP6623_RS22400	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS22405	COG1609	Transcriptional regulator
CFBP6623_RS22415	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS22420	COG0583	DNA-binding transcription factor activity
CFBP6623_RS22435	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS22440	COG1609	Transcriptional regulator
CFBP6623_RS22445	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6623_RS22460	COG3842	ATPase activity
CFBP6623_RS22465	COG1177	transmembrane transport
CFBP6623_RS22505	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP6623_RS22505	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP6623_RS22520	COG0668	transmembrane transport
CFBP6623_RS22540	COG1879	ABC-type sugar transport system periplasmic component
CFBP6623_RS22545	COG1129	ABC transporter
CFBP6623_RS22550	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS22555	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS22560	COG1609	Transcriptional regulator
CFBP6623_RS22570	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS22630	COG0714	Associated with various cellular activities
CFBP6623_RS22635	COG3256	nitric oxide reductase
CFBP6623_RS22650	COG1845	cytochrome c oxidase, subunit III
CFBP6623_RS22665	COG0163	prenyltransferase activity
CFBP6623_RS22670	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CFBP6623_RS22675	COG3189	MarR family transcriptional regulator
CFBP6623_RS22685	COG0826	peptidase U32
CFBP6623_RS22710	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CFBP6623_RS22720	COG4459	periplasmic nitrate reductase
CFBP6623_RS22735	COG0243	molybdopterin cofactor binding
CFBP6623_RS22745	COG3005	denitrification pathway
CFBP6623_RS22760	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS22765	COG1535	isochorismatase
CFBP6623_RS22765	COG3433	isochorismatase activity
CFBP6623_RS22770	COG1021	2,3-dihydroxybenzoate-AMP ligase
CFBP6623_RS22775	COG1169	isochorismate synthase
CFBP6623_RS22785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFBP6623_RS22785	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CFBP6623_RS22790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFBP6623_RS22810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6623_RS22815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6623_RS22820	COG1120	ATPase activity
CFBP6623_RS22825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS22835	COG1629	transport
CFBP6623_RS22835	COG4774	siderophore transport
CFBP6623_RS22840	COG1960	acyl-CoA dehydrogenase activity
CFBP6623_RS22845	COG0583	DNA-binding transcription factor activity
CFBP6623_RS22850	COG1609	Transcriptional regulator
CFBP6623_RS22860	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP6623_RS22870	COG3842	ATPase activity
CFBP6623_RS22880	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP6623_RS22885	COG0583	DNA-binding transcription factor activity
CFBP6623_RS22890	COG2814	Major facilitator Superfamily
CFBP6623_RS22895	COG1473	amidohydrolase
CFBP6623_RS22910	COG0747	negative chemotaxis
CFBP6623_RS22915	COG0601	transmembrane transport
CFBP6623_RS22920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS22925	COG0444	Belongs to the ABC transporter superfamily
CFBP6623_RS22930	COG4608	Belongs to the ABC transporter superfamily
CFBP6623_RS22935	COG0583	DNA-binding transcription factor activity
CFBP6623_RS22940	COG0747	negative chemotaxis
CFBP6623_RS22950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS22960	COG0693	protein deglycase activity
CFBP6623_RS22970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS22975	COG0601	transmembrane transport
CFBP6623_RS22980	COG4166	transmembrane transport
CFBP6623_RS22985	COG1473	amidohydrolase
CFBP6623_RS22990	COG4172	Belongs to the ABC transporter superfamily
CFBP6623_RS22995	COG2390	Transcriptional regulator
CFBP6623_RS23005	COG1175	transmembrane transport
CFBP6623_RS23010	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS23030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP6623_RS23060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP6623_RS23065	COG0850	regulation of cytokinetic process
CFBP6623_RS23070	COG2894	cell division
CFBP6623_RS23075	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CFBP6623_RS23085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6623_RS23090	COG5001	Diguanylate cyclase
CFBP6623_RS23120	COG1653	transport
CFBP6623_RS23125	COG1175	transmembrane transport
CFBP6623_RS23130	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS23135	COG3842	ATPase activity
CFBP6623_RS23145	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS23150	COG1054	Belongs to the UPF0176 family
CFBP6623_RS23160	COG2954	triphosphatase activity
CFBP6623_RS23165	COG0800	Aldolase
CFBP6623_RS23190	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CFBP6623_RS23230	COG0523	cobalamin synthesis protein
CFBP6623_RS23240	COG1846	Transcriptional regulator
CFBP6623_RS23245	COG1609	Transcriptional regulator
CFBP6623_RS23250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6623_RS23255	COG2801	Transposase and inactivated derivatives
CFBP6623_RS23255	COG3415	Transposase
CFBP6623_RS23265	COG3718	enzyme involved in inositol metabolism
CFBP6623_RS23275	COG3962	Belongs to the TPP enzyme family
CFBP6623_RS23280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6623_RS23295	COG0411	ABC transporter
CFBP6623_RS23310	COG0683	leucine binding
CFBP6623_RS23320	COG2207	Transcriptional regulator
CFBP6623_RS23330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS23340	COG0747	negative chemotaxis
CFBP6623_RS23345	COG4172	Belongs to the ABC transporter superfamily
CFBP6623_RS23360	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CFBP6623_RS23360	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6623_RS23370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP6623_RS23375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP6623_RS23380	COG1126	abc transporter atp-binding protein
CFBP6623_RS23385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6623_RS23390	COG0765	amino acid transport
CFBP6623_RS23395	COG0765	amino acid transport
CFBP6623_RS23405	COG3485	protocatechuate 3,4-dioxygenase
CFBP6623_RS23410	COG3485	protocatechuate 3,4-dioxygenase
CFBP6623_RS23415	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFBP6623_RS23425	COG0583	DNA-binding transcription factor activity
CFBP6623_RS23440	COG1414	Transcriptional regulator
CFBP6623_RS23450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFBP6623_RS23455	COG0183	Belongs to the thiolase family
CFBP6623_RS23460	COG1609	Transcriptional regulator
CFBP6623_RS23475	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6623_RS23480	COG0673	inositol 2-dehydrogenase activity
CFBP6623_RS23490	COG1609	Transcriptional regulator
CFBP6623_RS23495	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS23500	COG1175	transmembrane transport
CFBP6623_RS23530	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFBP6623_RS23560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP6623_RS23560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP6623_RS23580	COG0385	Bile acid
CFBP6623_RS23585	COG0667	Aldo Keto reductase
CFBP6623_RS23590	COG0583	DNA-binding transcription factor activity
CFBP6623_RS23600	COG2942	2-epimerase
CFBP6623_RS23605	COG1132	(ABC) transporter
CFBP6623_RS23615	COG0438	transferase activity, transferring glycosyl groups
CFBP6623_RS23650	COG0438	transferase activity, transferring glycosyl groups
CFBP6623_RS23650	COG1216	Glycosyl transferase, family 2
CFBP6623_RS23655	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFBP6623_RS23660	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFBP6623_RS23665	COG1088	dTDP-glucose 4,6-dehydratase activity
CFBP6623_RS23670	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CFBP6623_RS23675	COG0210	DNA helicase
CFBP6623_RS23685	COG4608	Belongs to the ABC transporter superfamily
CFBP6623_RS23690	COG0444	Belongs to the ABC transporter superfamily
CFBP6623_RS23695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS23700	COG0601	transmembrane transport
CFBP6623_RS23705	COG2186	Transcriptional regulator
CFBP6623_RS23710	COG1312	Catalyzes the dehydration of D-mannonate
CFBP6623_RS23725	COG5001	Diguanylate cyclase
CFBP6623_RS23725	COG3300	MHYT domain
CFBP6623_RS23740	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP6623_RS23750	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP6623_RS23755	COG0306	phosphate transporter
CFBP6623_RS23760	COG1392	Phosphate transport regulator
CFBP6623_RS23780	COG0745	RESPONSE REGULATOR receiver
CFBP6623_RS23785	COG5002	protein histidine kinase activity
CFBP6623_RS23835	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CFBP6623_RS23850	COG4774	siderophore transport
CFBP6623_RS23860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6623_RS23865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6623_RS23870	COG1120	ATPase activity
CFBP6623_RS23875	COG0583	DNA-binding transcription factor activity
CFBP6623_RS23915	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS23920	COG0583	DNA-binding transcription factor activity
CFBP6623_RS23930	COG3119	arylsulfatase activity
CFBP6623_RS23935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6623_RS23940	COG3842	ATPase activity
CFBP6623_RS23945	COG0165	Argininosuccinate lyase
CFBP6623_RS23950	COG0395	ABC-type sugar transport system, permease component
CFBP6623_RS23955	COG1175	transmembrane transport
CFBP6623_RS23960	COG2182	Extracellular solute-binding protein
CFBP6623_RS23965	COG1940	carbohydrate kinase activity
CFBP6623_RS23990	COG1486	melibiose metabolic process
CFBP6623_RS23995	COG0747	negative chemotaxis
CFBP6623_RS24000	COG0601	transmembrane transport
CFBP6623_RS24005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS24010	COG4172	Belongs to the ABC transporter superfamily
CFBP6623_RS24015	COG1486	melibiose metabolic process
CFBP6623_RS24020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6623_RS24025	COG0842	Transport permease protein
CFBP6623_RS24025	COG1129	ABC transporter
CFBP6623_RS24030	COG0842	Transport permease protein
CFBP6623_RS24045	COG0784	Response regulator, receiver
CFBP6623_RS24050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP6623_RS24060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6623_RS24065	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP6623_RS24080	COG0765	amino acid transport
CFBP6623_RS24090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6623_RS24100	COG3938	Belongs to the proline racemase family
CFBP6623_RS24115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6623_RS24120	COG0765	amino acid transport
CFBP6623_RS24125	COG0765	amino acid transport
CFBP6623_RS24135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6623_RS24150	COG0402	S-adenosylhomocysteine deaminase activity
CFBP6623_RS24160	COG0601	transmembrane transport
CFBP6623_RS24165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS24175	COG0402	S-adenosylhomocysteine deaminase activity
CFBP6623_RS24180	COG0444	Belongs to the ABC transporter superfamily
CFBP6623_RS24185	COG4608	Belongs to the ABC transporter superfamily
CFBP6623_RS24190	COG1802	Transcriptional regulator
CFBP6623_RS24195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP6623_RS24215	COG3237	CsbD-like
CFBP6623_RS24220	COG2197	response regulator
CFBP6623_RS24240	COG3383	formate dehydrogenase (NAD+) activity
CFBP6623_RS24250	COG2223	nitrite transmembrane transporter activity
CFBP6623_RS24260	COG1278	Cold shock
CFBP6623_RS24265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6623_RS24280	COG0747	negative chemotaxis
CFBP6623_RS24285	COG0601	transmembrane transport
CFBP6623_RS24290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS24295	COG4172	Belongs to the ABC transporter superfamily
CFBP6623_RS24300	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6623_RS24310	COG2186	Transcriptional regulator
CFBP6623_RS24315	COG0747	negative chemotaxis
CFBP6623_RS24320	COG0601	transmembrane transport
CFBP6623_RS24325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS24330	COG0405	Gamma-glutamyltransferase
CFBP6623_RS24355	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6623_RS24360	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6623_RS24370	COG3842	ATPase activity
CFBP6623_RS24385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP6623_RS24390	COG3181	Tripartite tricarboxylate transporter family receptor
CFBP6623_RS24395	COG5265	(ABC) transporter
CFBP6623_RS24400	COG0488	(ABC) transporter
CFBP6623_RS24420	COG1129	ABC transporter
CFBP6623_RS24425	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS24445	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6623_RS24460	COG4221	oxidoreductase activity
CFBP6623_RS24465	COG0583	DNA-binding transcription factor activity
CFBP6623_RS24470	COG1126	abc transporter atp-binding protein
CFBP6623_RS24475	COG0765	amino acid transport
CFBP6623_RS24480	COG0765	amino acid transport
CFBP6623_RS24485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6623_RS24490	COG3608	succinylglutamate desuccinylase aspartoacylase
CFBP6623_RS24495	COG0006	proline dipeptidase activity
CFBP6623_RS24500	COG2423	ornithine cyclodeaminase activity
CFBP6623_RS24505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFBP6623_RS24510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6623_RS24515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6623_RS24520	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6623_RS24525	COG1522	sequence-specific DNA binding
CFBP6623_RS24585	COG0110	maltose O-acetyltransferase activity
CFBP6623_RS24625	COG3209	COG3209 Rhs family protein
CFBP6623_RS24690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFBP6623_RS24695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP6623_RS24700	COG1845	cytochrome c oxidase, subunit III
CFBP6623_RS24705	COG1845	cytochrome c oxidase, subunit III
CFBP6623_RS24735	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP6623_RS24750	COG0436	Aminotransferase
CFBP6623_RS24770	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6623_RS24775	COG3836	Belongs to the HpcH HpaI aldolase family
CFBP6623_RS24800	COG5000	phosphorelay sensor kinase activity
CFBP6623_RS24830	COG3177	Filamentation induced by cAMP protein fic
CFBP6623_RS24835	COG0431	NADPH-dependent FMN reductase
CFBP6623_RS24845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6623_RS24855	COG4172	Belongs to the ABC transporter superfamily
CFBP6623_RS24860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6623_RS24885	COG0277	FAD linked oxidase domain protein
CFBP6623_RS24925	COG2963	transposase activity
CFBP6623_RS24930	COG3436	PFAM IS66 Orf2 family protein
CFBP6623_RS24935	COG4372	Transposase
CFBP6623_RS24940	COG2207	Transcriptional regulator
CFBP6623_RS24950	COG2080	2 iron, 2 sulfur cluster binding
CFBP6623_RS24955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CFBP6623_RS24960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFBP6623_RS24965	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFBP6623_RS24975	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6623_RS25025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP6623_RS25055	COG1192	Involved in chromosome partitioning
CFBP6623_RS25060	COG1475	DNA binding
CFBP6623_RS25065	COG1414	Transcriptional regulator
CFBP6623_RS25095	COG3838	Conjugal transfer protein Trbc
CFBP6623_RS25100	COG3702	type iv secretory pathway
CFBP6623_RS25105	COG3451	type IV secretory pathway VirB4
CFBP6623_RS25120	COG3704	protein secretion by the type IV secretion system
CFBP6623_RS25130	COG3736	Type IV secretory pathway, component VirB8
CFBP6623_RS25135	COG3504	Conjugal transfer protein
CFBP6623_RS25140	COG2948	multi-organism process
CFBP6623_RS25145	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CFBP6623_RS25235	COG3609	addiction module antidote protein, CC2985 family
CFBP6623_RS25275	COG3505	Type IV secretory pathway VirD4
CFBP6623_RS25315	COG2197	response regulator
CFBP6623_RS25330	COG2801	Transposase and inactivated derivatives
CFBP6623_RS25345	COG0693	protein deglycase activity
CFBP6623_RS25370	COG4221	oxidoreductase activity
CFBP6623_RS25375	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CFBP6623_RS25395	COG0583	DNA-binding transcription factor activity
CFBP6623_RS25435	COG3328	transposase activity
CFBP6623_RS25460	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CFBP6623_RS25565	COG0577	efflux transmembrane transporter activity
CFBP6623_RS25565	COG1136	(ABC) transporter
CFBP6623_RS25570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6623_RS25635	COG0753	catalase activity
CFBP6623_RS25655	COG4529	Protein conserved in bacteria
CFBP6623_RS25670	COG3437	response regulator, receiver
CFBP6623_RS25670	COG3850	Histidine kinase
CFBP6623_RS25670	COG4999	Histidine kinase
CFBP6623_RS25670	COG2205	protein histidine kinase activity
CFBP6623_RS25675	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CFBP6623_RS25685	COG5002	protein histidine kinase activity
CFBP6623_RS25725	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6623_RS25740	COG0835	chemotaxis
CFBP6623_RS25750	COG2197	response regulator
CFBP6623_RS25860	COG5001	Diguanylate cyclase
CFBP6623_RS25880	COG4644	lycopene metabolic process
CFBP6623_RS25910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFBP6623_RS25930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFBP6623_RS25995	COG2132	Multicopper oxidase
CFBP6623_RS26015	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CFBP6623_RS26020	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CFBP6623_RS26035	COG2217	Heavy metal translocating P-type atpase
CFBP6623_RS26055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP6623_RS26070	COG0583	DNA-binding transcription factor activity
CFBP6623_RS26090	COG0789	Transcriptional regulator
CFBP6623_RS26105	COG1937	Protein conserved in bacteria
CFBP6623_RS26120	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6623_RS26180	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CFBP6623_RS26205	COG3436	PFAM IS66 Orf2 family protein
CFBP6623_RS26210	COG2963	transposase activity
CFBP6623_RS26230	COG0210	DNA helicase
CFBP6623_RS26245	COG1074	ATP-dependent DNA helicase activity
CFBP6623_RS26335	COG1959	2 iron, 2 sulfur cluster binding
CFBP6623_RS26435	COG4644	lycopene metabolic process
CFBP6623_RS26490	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP6623_RS26500	COG3436	PFAM IS66 Orf2 family protein
CFBP6623_RS26530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6623_RS26580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6623_RS26605	COG0789	Transcriptional regulator
CFBP6623_RS26615	COG1695	Transcriptional regulator