locus-tag	class	description
CFBP6624_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFBP6624_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP6624_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFBP6624_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFBP6624_RS00025	COG1420	regulation of RNA biosynthetic process
CFBP6624_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFBP6624_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP6624_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFBP6624_RS00050	COG1137	ATPase activity
CFBP6624_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CFBP6624_RS00065	COG0616	signal peptide processing
CFBP6624_RS00070	COG0776	regulation of translation
CFBP6624_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP6624_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFBP6624_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFBP6624_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFBP6624_RS00115	COG0728	peptidoglycan biosynthetic process
CFBP6624_RS00120	COG0346	lactoylglutathione lyase activity
CFBP6624_RS00125	COG0180	Tryptophanyl-tRNA synthetase
CFBP6624_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CFBP6624_RS00140	COG1214	PFAM Peptidase M22, glycoprotease
CFBP6624_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP6624_RS00165	COG1702	phosphate starvation-inducible protein PhoH
CFBP6624_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFBP6624_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CFBP6624_RS00185	COG1396	sequence-specific DNA binding
CFBP6624_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFBP6624_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFBP6624_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6624_RS00210	COG0242	peptide deformylase activity
CFBP6624_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFBP6624_RS00220	COG0101	tRNA pseudouridine synthase activity
CFBP6624_RS00225	COG1393	Belongs to the ArsC family
CFBP6624_RS00235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP6624_RS00240	COG2171	N-acyltransferase activity
CFBP6624_RS00250	COG0840	transmembrane signaling receptor activity
CFBP6624_RS00260	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6624_RS00285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFBP6624_RS00300	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CFBP6624_RS00305	COG0706	membrane insertase activity
CFBP6624_RS00310	COG0594	ribonuclease P activity
CFBP6624_RS00315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFBP6624_RS00320	COG0840	transmembrane signaling receptor activity
CFBP6624_RS00345	COG3842	ATPase activity
CFBP6624_RS00350	COG1175	transmembrane transport
CFBP6624_RS00355	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS00370	COG0427	acetyl-CoA hydrolase
CFBP6624_RS00380	COG3938	Belongs to the proline racemase family
CFBP6624_RS00385	COG0418	dihydroorotase activity
CFBP6624_RS00390	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFBP6624_RS00410	COG0166	Belongs to the GPI family
CFBP6624_RS00415	COG0318	PFAM AMP-dependent synthetase and ligase
CFBP6624_RS00420	COG3842	ATPase activity
CFBP6624_RS00425	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6624_RS00430	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP6624_RS00435	COG4774	siderophore transport
CFBP6624_RS00485	COG2326	polyphosphate kinase activity
CFBP6624_RS00490	COG5002	protein histidine kinase activity
CFBP6624_RS00495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFBP6624_RS00500	COG0573	inorganic phosphate transmembrane transporter activity
CFBP6624_RS00510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFBP6624_RS00515	COG0704	Plays a role in the regulation of phosphate uptake
CFBP6624_RS00520	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS00535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFBP6624_RS00540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFBP6624_RS00550	COG2967	ApaG domain
CFBP6624_RS00560	COG0717	Belongs to the dCTP deaminase family
CFBP6624_RS00570	COG0582	viral genome integration into host DNA
CFBP6624_RS00580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6624_RS00640	COG0210	DNA helicase
CFBP6624_RS00695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFBP6624_RS00745	COG0167	dihydroorotate dehydrogenase activity
CFBP6624_RS00760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP6624_RS00780	COG1959	2 iron, 2 sulfur cluster binding
CFBP6624_RS00785	COG1201	RNA secondary structure unwinding
CFBP6624_RS00805	COG0730	response to heat
CFBP6624_RS00820	COG1960	acyl-CoA dehydrogenase activity
CFBP6624_RS00825	COG0183	Belongs to the thiolase family
CFBP6624_RS00830	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP6624_RS00830	COG1024	Enoyl-CoA hydratase
CFBP6624_RS00870	COG1320	monovalent cation:proton antiporter activity
CFBP6624_RS00875	COG2212	antiporter activity
CFBP6624_RS00880	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP6624_RS00885	COG0651	ATP synthesis coupled electron transport
CFBP6624_RS00890	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP6624_RS00895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFBP6624_RS00895	COG2111	Na H antiporter
CFBP6624_RS00905	COG0840	transmembrane signaling receptor activity
CFBP6624_RS00915	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS00920	COG2198	Histidine kinase
CFBP6624_RS00920	COG0643	Histidine kinase
CFBP6624_RS00925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CFBP6624_RS00930	COG2201	protein-glutamate methylesterase activity
CFBP6624_RS00935	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS00940	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CFBP6624_RS00950	COG1766	The M ring may be actively involved in energy transduction
CFBP6624_RS00955	COG2771	luxR family
CFBP6624_RS00965	COG2972	Histidine kinase
CFBP6624_RS00965	COG0840	transmembrane signaling receptor activity
CFBP6624_RS00970	COG2198	Histidine kinase
CFBP6624_RS00970	COG2205	protein histidine kinase activity
CFBP6624_RS00970	COG0784	Response regulator, receiver
CFBP6624_RS00980	COG1970	mechanosensitive ion channel activity
CFBP6624_RS00985	COG0436	Aminotransferase
CFBP6624_RS01000	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CFBP6624_RS01005	COG0424	maF-like protein
CFBP6624_RS01010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFBP6624_RS01020	COG5328	Belongs to the UPF0262 family
CFBP6624_RS01025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFBP6624_RS01035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFBP6624_RS01050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP6624_RS01070	COG1338	Plays a role in the flagellum-specific transport system
CFBP6624_RS01080	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CFBP6624_RS01090	COG1706	bacterial-type flagellum-dependent cell motility
CFBP6624_RS01095	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CFBP6624_RS01100	COG4786	Flagellar basal body rod
CFBP6624_RS01105	COG1677	Flagellar hook-basal body complex protein FliE
CFBP6624_RS01110	COG1558	bacterial-type flagellum-dependent cell motility
CFBP6624_RS01115	COG1815	bacterial-type flagellum-dependent cell motility
CFBP6624_RS01125	COG1157	protein secretion by the type III secretion system
CFBP6624_RS01130	COG4786	Flagellar basal body rod
CFBP6624_RS01140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CFBP6624_RS01145	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP6624_RS01150	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP6624_RS01155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP6624_RS01160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP6624_RS01175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP6624_RS01185	COG1360	Flagellar Motor Protein
CFBP6624_RS01210	COG1749	Flagellar hook protein flgE
CFBP6624_RS01230	COG5443	negative regulation of bacterial-type flagellum assembly
CFBP6624_RS01235	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CFBP6624_RS01245	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP6624_RS01285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFBP6624_RS01290	COG1609	Transcriptional regulator
CFBP6624_RS01295	COG1653	transport
CFBP6624_RS01300	COG1175	transmembrane transport
CFBP6624_RS01305	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS01310	COG0366	Alpha amylase catalytic
CFBP6624_RS01315	COG3842	ATPase activity
CFBP6624_RS01325	COG3609	addiction module antidote protein, CC2985 family
CFBP6624_RS01340	COG0129	dihydroxy-acid dehydratase activity
CFBP6624_RS01345	COG0363	glucosamine-6-phosphate deaminase activity
CFBP6624_RS01350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFBP6624_RS01355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS01365	COG2081	HI0933 family
CFBP6624_RS01385	COG2224	Isocitrate lyase
CFBP6624_RS01400	COG3842	ATPase activity
CFBP6624_RS01405	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP6624_RS01410	COG1177	transmembrane transport
CFBP6624_RS01425	COG2205	protein histidine kinase activity
CFBP6624_RS01435	COG0248	Ppx GppA phosphatase
CFBP6624_RS01440	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CFBP6624_RS01445	COG0477	Major facilitator Superfamily
CFBP6624_RS01485	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFBP6624_RS01490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFBP6624_RS01500	COG0142	geranyltranstransferase activity
CFBP6624_RS01525	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP6624_RS01530	COG0752	glycyl-tRNA synthetase alpha subunit
CFBP6624_RS01540	COG1704	LemA family
CFBP6624_RS01545	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFBP6624_RS01555	COG0751	glycine-tRNA ligase activity
CFBP6624_RS01565	COG1683	Conserved Protein
CFBP6624_RS01570	COG0840	transmembrane signaling receptor activity
CFBP6624_RS01580	COG0151	Belongs to the GarS family
CFBP6624_RS01585	COG2183	response to ionizing radiation
CFBP6624_RS01590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP6624_RS01615	COG0583	DNA-binding transcription factor activity
CFBP6624_RS01635	COG0306	phosphate transporter
CFBP6624_RS01645	COG0561	phosphatase activity
CFBP6624_RS01650	COG0438	transferase activity, transferring glycosyl groups
CFBP6624_RS01655	COG2186	Transcriptional regulator
CFBP6624_RS01670	COG0583	DNA-binding transcription factor activity
CFBP6624_RS01675	COG0277	FAD linked oxidase domain protein
CFBP6624_RS01685	COG0277	FAD linked oxidase domain protein
CFBP6624_RS01690	COG0247	lactate metabolic process
CFBP6624_RS01700	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6624_RS01705	COG2818	Glycosylase
CFBP6624_RS01715	COG2855	membrane
CFBP6624_RS01720	COG0583	DNA-binding transcription factor activity
CFBP6624_RS01750	COG0124	histidyl-tRNA synthetase
CFBP6624_RS01760	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFBP6624_RS01765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFBP6624_RS01770	COG2259	Doxx family
CFBP6624_RS01785	COG0459	protein refolding
CFBP6624_RS01790	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFBP6624_RS01800	COG0196	riboflavin kinase activity
CFBP6624_RS01805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFBP6624_RS01815	COG0590	tRNA wobble adenosine to inosine editing
CFBP6624_RS01820	COG1187	pseudouridine synthase activity
CFBP6624_RS01825	COG0742	ribosomal rna small subunit methyltransferase
CFBP6624_RS01830	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP6624_RS01835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP6624_RS01835	COG0475	glutathione-regulated potassium exporter activity
CFBP6624_RS01840	COG0312	modulator of DNA gyrase
CFBP6624_RS01855	COG1519	Transferase
CFBP6624_RS01870	COG1663	tetraacyldisaccharide 4'-kinase activity
CFBP6624_RS01880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFBP6624_RS01890	COG5001	Diguanylate cyclase
CFBP6624_RS01890	COG3300	MHYT domain
CFBP6624_RS01895	COG3386	PFAM SMP-30 Gluconolaconase
CFBP6624_RS01900	COG0800	Aldolase
CFBP6624_RS01905	COG3734	2-keto-3-deoxy-galactonokinase
CFBP6624_RS01910	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS01920	COG2197	response regulator
CFBP6624_RS01925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6624_RS01935	COG0598	Magnesium transport protein CorA
CFBP6624_RS01940	COG3158	transport of potassium into the cell
CFBP6624_RS01955	COG0356	it plays a direct role in the translocation of protons across the membrane
CFBP6624_RS01965	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP6624_RS01970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP6624_RS01980	COG0300	oxidoreductase activity
CFBP6624_RS01985	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFBP6624_RS02010	COG0009	L-threonylcarbamoyladenylate synthase
CFBP6624_RS02020	COG4638	Rieske (2fe-2S)
CFBP6624_RS02045	COG1960	acyl-CoA dehydrogenase activity
CFBP6624_RS02060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFBP6624_RS02065	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CFBP6624_RS02070	COG0840	transmembrane signaling receptor activity
CFBP6624_RS02080	COG1522	sequence-specific DNA binding
CFBP6624_RS02105	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFBP6624_RS02110	COG1741	Belongs to the pirin family
CFBP6624_RS02115	COG1722	exodeoxyribonuclease VII activity
CFBP6624_RS02120	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFBP6624_RS02125	COG1268	BioY protein
CFBP6624_RS02130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFBP6624_RS02135	COG1122	ATPase activity
CFBP6624_RS02140	COG3214	Protein conserved in bacteria
CFBP6624_RS02145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP6624_RS02145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP6624_RS02150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFBP6624_RS02165	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP6624_RS02170	COG0484	heat shock protein binding
CFBP6624_RS02180	COG0259	pyridoxamine-phosphate oxidase activity
CFBP6624_RS02200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP6624_RS02210	COG0312	modulator of DNA gyrase
CFBP6624_RS02225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP6624_RS02230	COG0109	protoheme IX farnesyltransferase activity
CFBP6624_RS02240	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CFBP6624_RS02255	COG3346	SURF1 family
CFBP6624_RS02260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CFBP6624_RS02265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFBP6624_RS02270	COG0328	RNA-DNA hybrid ribonuclease activity
CFBP6624_RS02280	COG0678	peroxiredoxin activity
CFBP6624_RS02280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFBP6624_RS02290	COG1678	Uncharacterized ACR, COG1678
CFBP6624_RS02295	COG3237	CsbD-like
CFBP6624_RS02305	COG5001	Diguanylate cyclase
CFBP6624_RS02305	COG3300	MHYT domain
CFBP6624_RS02310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP6624_RS02315	COG0612	Peptidase, M16
CFBP6624_RS02330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP6624_RS02335	COG1802	Transcriptional regulator
CFBP6624_RS02355	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CFBP6624_RS02365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6624_RS02375	COG1194	a g-specific adenine glycosylase
CFBP6624_RS02390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFBP6624_RS02395	COG1196	nuclear chromosome segregation
CFBP6624_RS02400	COG2514	catechol 2,3-dioxygenase activity
CFBP6624_RS02405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFBP6624_RS02405	COG0574	Belongs to the PEP-utilizing enzyme family
CFBP6624_RS02420	COG1301	dicarboxylic acid transport
CFBP6624_RS02450	COG0579	oxidoreductase
CFBP6624_RS02475	COG2895	sulfate adenylyltransferase (ATP) activity
CFBP6624_RS02480	COG0175	sulfate reduction
CFBP6624_RS02485	COG0175	sulfate reduction
CFBP6624_RS02490	COG1959	2 iron, 2 sulfur cluster binding
CFBP6624_RS02495	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CFBP6624_RS02500	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP6624_RS02505	COG4208	sulfate ABC transporter
CFBP6624_RS02510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP6624_RS02535	COG2199	diguanylate cyclase activity
CFBP6624_RS02535	COG2203	Gaf domain
CFBP6624_RS02535	COG2200	EAL domain
CFBP6624_RS02545	COG1309	transcriptional regulator
CFBP6624_RS02550	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS02555	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CFBP6624_RS02600	COG0477	Major facilitator Superfamily
CFBP6624_RS02620	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CFBP6624_RS02620	COG1793	dna ligase
CFBP6624_RS02640	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6624_RS02645	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6624_RS02660	COG1846	Transcriptional regulator
CFBP6624_RS02665	COG1764	response to oxidative stress
CFBP6624_RS02705	COG0488	(ABC) transporter
CFBP6624_RS02720	COG0433	COG0433 Predicted ATPase
CFBP6624_RS02730	COG1733	regulation of RNA biosynthetic process
CFBP6624_RS02735	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CFBP6624_RS02750	COG0656	L-ascorbic acid biosynthetic process
CFBP6624_RS02755	COG3781	membrane
CFBP6624_RS02760	COG2378	regulation of single-species biofilm formation
CFBP6624_RS02770	COG4106	trans-aconitate 2-methyltransferase activity
CFBP6624_RS02775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP6624_RS02780	COG0840	transmembrane signaling receptor activity
CFBP6624_RS02785	COG0583	DNA-binding transcription factor activity
CFBP6624_RS02800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP6624_RS02820	COG3909	cytochrome
CFBP6624_RS02825	COG2010	Cytochrome c
CFBP6624_RS02860	COG0789	Transcriptional regulator
CFBP6624_RS02890	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP6624_RS02920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6624_RS02930	COG2169	Transcriptional regulator
CFBP6624_RS02930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP6624_RS02940	COG2514	catechol 2,3-dioxygenase activity
CFBP6624_RS02955	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CFBP6624_RS02960	COG1272	protein, Hemolysin III
CFBP6624_RS02970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP6624_RS02975	COG2111	Na H antiporter
CFBP6624_RS02975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFBP6624_RS02980	COG2111	Na H antiporter
CFBP6624_RS02985	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP6624_RS02990	COG0651	ATP synthesis coupled electron transport
CFBP6624_RS02995	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP6624_RS03000	COG2212	antiporter activity
CFBP6624_RS03005	COG1320	monovalent cation:proton antiporter activity
CFBP6624_RS03010	COG4957	zinc ion binding
CFBP6624_RS03025	COG2166	iron-sulfur cluster assembly
CFBP6624_RS03035	COG2205	protein histidine kinase activity
CFBP6624_RS03090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP6624_RS03095	COG2983	Belongs to the UPF0260 family
CFBP6624_RS03150	COG1621	beta-fructofuranosidase activity
CFBP6624_RS03155	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFBP6624_RS03220	COG4695	Portal protein
CFBP6624_RS03335	COG4235	cytochrome complex assembly
CFBP6624_RS03340	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CFBP6624_RS03345	COG1138	Cytochrome C-type biogenesis protein
CFBP6624_RS03350	COG3088	subunit of a heme lyase
CFBP6624_RS03355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6624_RS03370	COG3011	Protein conserved in bacteria
CFBP6624_RS03380	COG3713	MltA-interacting MipA family protein
CFBP6624_RS03385	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFBP6624_RS03395	COG2202	Pas domain
CFBP6624_RS03395	COG2205	protein histidine kinase activity
CFBP6624_RS03405	COG0308	aminopeptidase N
CFBP6624_RS03415	COG0697	spore germination
CFBP6624_RS03435	COG0443	Heat shock 70 kDa protein
CFBP6624_RS03440	COG3706	GGDEF domain
CFBP6624_RS03445	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS03465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP6624_RS03490	COG1733	regulation of RNA biosynthetic process
CFBP6624_RS03495	COG1968	undecaprenyl-diphosphatase activity
CFBP6624_RS03500	COG2239	Acts as a magnesium transporter
CFBP6624_RS03505	COG2814	Major facilitator Superfamily
CFBP6624_RS03530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFBP6624_RS03555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP6624_RS03600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CFBP6624_RS03605	COG0741	lytic transglycosylase activity
CFBP6624_RS03610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6624_RS03615	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFBP6624_RS03625	COG0840	transmembrane signaling receptor activity
CFBP6624_RS03635	COG1758	RNA polymerase activity
CFBP6624_RS03660	COG0736	holo-[acyl-carrier-protein] synthase activity
CFBP6624_RS03665	COG0681	Belongs to the peptidase S26 family
CFBP6624_RS03670	COG0571	ribonuclease III activity
CFBP6624_RS03675	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFBP6624_RS03685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP6624_RS03690	COG0784	Response regulator, receiver
CFBP6624_RS03695	COG1381	Involved in DNA repair and RecF pathway recombination
CFBP6624_RS03705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP6624_RS03715	COG1418	mRNA catabolic process
CFBP6624_RS03725	COG0346	lactoylglutathione lyase activity
CFBP6624_RS03735	COG1116	anion transmembrane transporter activity
CFBP6624_RS03740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6624_RS03745	COG3443	Belongs to the bacterial solute-binding protein 9 family
CFBP6624_RS03750	COG0668	transmembrane transport
CFBP6624_RS03760	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CFBP6624_RS03790	COG1742	UPF0060 membrane protein
CFBP6624_RS03810	COG1183	phosphatidylcholine synthase activity
CFBP6624_RS03815	COG0688	phosphatidylethanolamine metabolic process
CFBP6624_RS03820	COG5265	(ABC) transporter
CFBP6624_RS03865	COG2852	Protein conserved in bacteria
CFBP6624_RS03875	COG0215	cysteine-tRNA ligase activity
CFBP6624_RS03880	COG4221	oxidoreductase activity
CFBP6624_RS03885	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFBP6624_RS03890	COG1286	toxin biosynthetic process
CFBP6624_RS03910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP6624_RS03920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CFBP6624_RS03955	COG0359	binds to the 23S rRNA
CFBP6624_RS03965	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFBP6624_RS03970	COG0360	Binds together with S18 to 16S ribosomal RNA
CFBP6624_RS03980	COG0667	Aldo Keto reductase
CFBP6624_RS03985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CFBP6624_RS03995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6624_RS04000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP6624_RS04005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFBP6624_RS04010	COG1561	YicC-like family, N-terminal region
CFBP6624_RS04015	COG0194	GDP metabolic process
CFBP6624_RS04020	COG0400	carboxylic ester hydrolase activity
CFBP6624_RS04025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFBP6624_RS04030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP6624_RS04040	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CFBP6624_RS04055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP6624_RS04075	COG2203	Gaf domain
CFBP6624_RS04075	COG5001	Diguanylate cyclase
CFBP6624_RS04075	COG4251	negative regulation of phosphorylation
CFBP6624_RS04075	COG3706	GGDEF domain
CFBP6624_RS04080	COG5001	Diguanylate cyclase
CFBP6624_RS04080	COG3300	MHYT domain
CFBP6624_RS04085	COG4191	Histidine kinase
CFBP6624_RS04100	COG0488	(ABC) transporter
CFBP6624_RS04105	COG3706	GGDEF domain
CFBP6624_RS04115	COG0105	UTP biosynthetic process
CFBP6624_RS04135	COG0314	molybdopterin synthase activity
CFBP6624_RS04145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFBP6624_RS04150	COG0322	excinuclease ABC activity
CFBP6624_RS04155	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS04165	COG0625	glutathione transferase activity
CFBP6624_RS04190	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CFBP6624_RS04195	COG0243	molybdopterin cofactor binding
CFBP6624_RS04220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFBP6624_RS04225	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFBP6624_RS04230	COG2226	methyltransferase
CFBP6624_RS04235	COG0628	permease
CFBP6624_RS04240	COG2255	four-way junction helicase activity
CFBP6624_RS04245	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CFBP6624_RS04250	COG0248	Ppx GppA phosphatase
CFBP6624_RS04275	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CFBP6624_RS04285	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFBP6624_RS04290	COG0477	Major facilitator Superfamily
CFBP6624_RS04295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFBP6624_RS04300	COG4452	Inner membrane protein CreD
CFBP6624_RS04305	COG0840	transmembrane signaling receptor activity
CFBP6624_RS04310	COG0659	secondary active sulfate transmembrane transporter activity
CFBP6624_RS04320	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP6624_RS04325	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CFBP6624_RS04340	COG0113	porphobilinogen synthase activity
CFBP6624_RS04365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFBP6624_RS04370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFBP6624_RS04375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP6624_RS04375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP6624_RS04385	COG1280	lysine exporter protein (LysE YggA)
CFBP6624_RS04390	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFBP6624_RS04395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFBP6624_RS04400	COG2814	Major facilitator Superfamily
CFBP6624_RS04405	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CFBP6624_RS04425	COG0416	fatty acid biosynthetic process
CFBP6624_RS04430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFBP6624_RS04435	COG0776	regulation of translation
CFBP6624_RS04470	COG0601	transmembrane transport
CFBP6624_RS04475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS04480	COG0444	Belongs to the ABC transporter superfamily
CFBP6624_RS04490	COG0747	negative chemotaxis
CFBP6624_RS04500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFBP6624_RS04505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFBP6624_RS04520	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFBP6624_RS04525	COG0583	DNA-binding transcription factor activity
CFBP6624_RS04535	COG0737	Belongs to the 5'-nucleotidase family
CFBP6624_RS04565	COG2897	thiosulfate sulfurtransferase activity
CFBP6624_RS04580	COG0415	Belongs to the DNA photolyase family
CFBP6624_RS04590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP6624_RS04620	COG3932	Exopolysaccharide synthesis, ExoD
CFBP6624_RS04625	COG1238	metal cluster binding
CFBP6624_RS04700	COG1612	heme a metabolic process
CFBP6624_RS04710	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFBP6624_RS04715	COG0010	Belongs to the arginase family
CFBP6624_RS04720	COG1396	sequence-specific DNA binding
CFBP6624_RS04725	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CFBP6624_RS04730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFBP6624_RS04735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFBP6624_RS04745	COG1832	CoA-binding protein
CFBP6624_RS04775	COG2199	diguanylate cyclase activity
CFBP6624_RS04780	COG0740	serine-type endopeptidase activity
CFBP6624_RS04785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFBP6624_RS04800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFBP6624_RS04810	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP6624_RS04835	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6624_RS04840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6624_RS04845	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6624_RS04855	COG0649	NAD binding
CFBP6624_RS04865	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CFBP6624_RS04870	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CFBP6624_RS04880	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CFBP6624_RS04885	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6624_RS04895	COG0713	ATP synthesis coupled electron transport
CFBP6624_RS04910	COG1007	ATP synthesis coupled electron transport
CFBP6624_RS04930	COG0442	prolyl-tRNA aminoacylation
CFBP6624_RS04940	COG1136	(ABC) transporter
CFBP6624_RS04960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP6624_RS04970	COG0784	Response regulator, receiver
CFBP6624_RS04985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFBP6624_RS04990	COG0477	Major facilitator Superfamily
CFBP6624_RS05005	COG0557	exoribonuclease II activity
CFBP6624_RS05010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFBP6624_RS05020	COG0758	DNA mediated transformation
CFBP6624_RS05025	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CFBP6624_RS05035	COG0540	Belongs to the ATCase OTCase family
CFBP6624_RS05040	COG1960	acyl-CoA dehydrogenase activity
CFBP6624_RS05045	COG0456	acetyltransferase
CFBP6624_RS05060	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFBP6624_RS05065	COG2824	Alkylphosphonate utilization operon protein PhnA
CFBP6624_RS05070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CFBP6624_RS05075	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP6624_RS05080	COG0154	amidase activity
CFBP6624_RS05085	COG3811	Belongs to the UPF0386 family
CFBP6624_RS05100	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP6624_RS05110	COG0456	acetyltransferase
CFBP6624_RS05125	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CFBP6624_RS05130	COG0439	Biotin carboxylase
CFBP6624_RS05135	COG0511	ligase activity, forming carbon-carbon bonds
CFBP6624_RS05140	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP6624_RS05150	COG0436	Aminotransferase
CFBP6624_RS05170	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS05175	COG1530	ribonuclease E activity
CFBP6624_RS05190	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP6624_RS05210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFBP6624_RS05215	COG0384	phenazine biosynthesis protein PhzF
CFBP6624_RS05230	COG0633	Ferredoxin
CFBP6624_RS05240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFBP6624_RS05245	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFBP6624_RS05250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFBP6624_RS05260	COG3768	UPF0283 membrane protein
CFBP6624_RS05265	COG3106	COG3106 Predicted ATPase
CFBP6624_RS05290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFBP6624_RS05325	COG0537	adenosine 5'-monophosphoramidase activity
CFBP6624_RS05350	COG0052	Belongs to the universal ribosomal protein uS2 family
CFBP6624_RS05355	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFBP6624_RS05360	COG0528	UMP kinase activity
CFBP6624_RS05365	COG0233	cytoplasmic translational termination
CFBP6624_RS05370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFBP6624_RS05380	COG0750	zinc metalloprotease
CFBP6624_RS05385	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP6624_RS05390	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP6624_RS05395	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP6624_RS05400	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP6624_RS05405	COG3494	Protein of unknown function (DUF1009)
CFBP6624_RS05410	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP6624_RS05415	COG0372	Belongs to the citrate synthase family
CFBP6624_RS05430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFBP6624_RS05440	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CFBP6624_RS05445	COG0148	phosphopyruvate hydratase activity
CFBP6624_RS05455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFBP6624_RS05460	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP6624_RS05460	COG0022	dehydrogenase e1 component
CFBP6624_RS05470	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP6624_RS05480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFBP6624_RS05490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFBP6624_RS05495	COG0697	spore germination
CFBP6624_RS05515	COG2867	negative regulation of translational initiation
CFBP6624_RS05525	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFBP6624_RS05525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFBP6624_RS05535	COG3852	Histidine kinase
CFBP6624_RS05540	COG2204	response regulator
CFBP6624_RS05545	COG5000	phosphorelay sensor kinase activity
CFBP6624_RS05550	COG2204	response regulator
CFBP6624_RS05555	COG0569	domain protein
CFBP6624_RS05560	COG1923	regulation of RNA biosynthetic process
CFBP6624_RS05565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFBP6624_RS05570	COG3956	TIGRFAM MazG family protein
CFBP6624_RS05585	COG1648	precorrin-2 dehydrogenase activity
CFBP6624_RS05585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP6624_RS05620	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CFBP6624_RS05635	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP6624_RS05635	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP6624_RS05640	COG0509	glycine decarboxylation via glycine cleavage system
CFBP6624_RS05645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP6624_RS05670	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFBP6624_RS05675	COG0564	pseudouridine synthase activity
CFBP6624_RS05695	COG0251	oxidation-reduction process
CFBP6624_RS05700	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CFBP6624_RS05710	COG1671	Belongs to the UPF0178 family
CFBP6624_RS05725	COG0450	alkyl hydroperoxide reductase
CFBP6624_RS05730	COG0625	glutathione transferase activity
CFBP6624_RS05735	COG2860	membrane
CFBP6624_RS05775	COG0084	hydrolase, TatD family'
CFBP6624_RS05780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP6624_RS05790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFBP6624_RS05855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP6624_RS05860	COG2095	MarC family integral membrane protein
CFBP6624_RS05865	COG0517	IMP dehydrogenase activity
CFBP6624_RS05865	COG0617	tRNA 3'-terminal CCA addition
CFBP6624_RS05865	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CFBP6624_RS05875	COG0629	single-stranded DNA binding
CFBP6624_RS05880	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFBP6624_RS05890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFBP6624_RS05895	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFBP6624_RS05910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP6624_RS05915	COG1121	(ABC) transporter
CFBP6624_RS05935	COG0667	Aldo Keto reductase
CFBP6624_RS05945	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFBP6624_RS06030	COG2239	Acts as a magnesium transporter
CFBP6624_RS06035	COG0243	molybdopterin cofactor binding
CFBP6624_RS06045	COG0242	peptide deformylase activity
CFBP6624_RS06060	COG2202	Pas domain
CFBP6624_RS06060	COG2205	protein histidine kinase activity
CFBP6624_RS06075	COG0321	lipoyl(octanoyl) transferase activity
CFBP6624_RS06080	COG1064	alcohol dehydrogenase
CFBP6624_RS06110	COG1862	Preprotein translocase
CFBP6624_RS06130	COG2124	cytochrome p450
CFBP6624_RS06145	COG0596	Alpha beta hydrolase
CFBP6624_RS06160	COG0626	cystathionine gamma-synthase activity
CFBP6624_RS06165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6624_RS06170	COG4597	amino acid ABC transporter
CFBP6624_RS06175	COG0765	amino acid transport
CFBP6624_RS06180	COG1126	abc transporter atp-binding protein
CFBP6624_RS06200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFBP6624_RS06215	COG0436	Aminotransferase
CFBP6624_RS06245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP6624_RS06255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP6624_RS06260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6624_RS06265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP6624_RS06280	COG3243	poly(R)-hydroxyalkanoic acid synthase
CFBP6624_RS06285	COG1489	DNA binding
CFBP6624_RS06290	COG0024	Methionine aminopeptidase
CFBP6624_RS06295	COG2003	Belongs to the UPF0758 family
CFBP6624_RS06310	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CFBP6624_RS06325	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFBP6624_RS06330	COG0546	phosphoglycolate phosphatase activity
CFBP6624_RS06345	COG0114	fumarate hydratase activity
CFBP6624_RS06350	COG0504	CTP synthase activity
CFBP6624_RS06360	COG0149	triose-phosphate isomerase activity
CFBP6624_RS06370	COG0187	DNA topoisomerase II activity
CFBP6624_RS06380	COG0740	serine-type endopeptidase activity
CFBP6624_RS06390	COG0640	Transcriptional regulator
CFBP6624_RS06395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFBP6624_RS06400	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS06425	COG3264	Mechanosensitive ion channel
CFBP6624_RS06425	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CFBP6624_RS06495	COG1127	ABC transporter
CFBP6624_RS06500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFBP6624_RS06505	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6624_RS06515	COG0281	malic enzyme
CFBP6624_RS06515	COG0280	phosphate acetyltransferase
CFBP6624_RS06535	COG0778	Nitroreductase
CFBP6624_RS06540	COG0823	Involved in the tonB-independent uptake of proteins
CFBP6624_RS06560	COG1368	sulfuric ester hydrolase activity
CFBP6624_RS06585	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFBP6624_RS06610	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFBP6624_RS06630	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFBP6624_RS06665	COG0512	Glutamine amidotransferase of anthranilate synthase
CFBP6624_RS06665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFBP6624_RS06670	COG0343	queuine tRNA-ribosyltransferase activity
CFBP6624_RS06675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFBP6624_RS06690	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFBP6624_RS06715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFBP6624_RS06720	COG0134	indole-3-glycerol-phosphate synthase activity
CFBP6624_RS06725	COG0315	cyclic pyranopterin monophosphate synthase activity
CFBP6624_RS06730	COG0303	'Molybdopterin
CFBP6624_RS06735	COG3706	GGDEF domain
CFBP6624_RS06745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP6624_RS06745	COG0475	glutathione-regulated potassium exporter activity
CFBP6624_RS06755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFBP6624_RS06760	COG0697	spore germination
CFBP6624_RS06765	COG2814	Major facilitator Superfamily
CFBP6624_RS06770	COG0746	molybdenum cofactor guanylyltransferase activity
CFBP6624_RS06775	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFBP6624_RS06780	COG0739	heme binding
CFBP6624_RS06785	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP6624_RS06790	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CFBP6624_RS06795	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP6624_RS06800	COG0805	protein transport
CFBP6624_RS06805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP6624_RS06810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP6624_RS06815	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFBP6624_RS06820	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFBP6624_RS06825	COG1472	Belongs to the glycosyl hydrolase 3 family
CFBP6624_RS06835	COG0018	arginyl-trna synthetase
CFBP6624_RS06840	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CFBP6624_RS06845	COG0316	Belongs to the HesB IscA family
CFBP6624_RS06870	COG0525	valine-tRNA ligase activity
CFBP6624_RS06880	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP6624_RS06910	COG0655	NAD(P)H dehydrogenase (quinone) activity
CFBP6624_RS06915	COG1058	Belongs to the CinA family
CFBP6624_RS06915	COG1546	Belongs to the CinA family
CFBP6624_RS06920	COG0589	response to stress
CFBP6624_RS06925	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CFBP6624_RS06935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFBP6624_RS06950	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP6624_RS06965	COG1132	(ABC) transporter
CFBP6624_RS06970	COG0628	permease
CFBP6624_RS07005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFBP6624_RS07015	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFBP6624_RS07025	COG0302	gtp cyclohydrolase
CFBP6624_RS07030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFBP6624_RS07035	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP6624_RS07045	COG0516	GMP reductase activity
CFBP6624_RS07045	COG0517	IMP dehydrogenase activity
CFBP6624_RS07075	COG1760	l-serine dehydratase
CFBP6624_RS07110	COG0583	DNA-binding transcription factor activity
CFBP6624_RS07140	COG1475	DNA binding
CFBP6624_RS07180	COG4396	Host-nuclease inhibitor protein Gam
CFBP6624_RS07245	COG2369	cell adhesion
CFBP6624_RS07380	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFBP6624_RS07380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFBP6624_RS07390	COG0347	Belongs to the P(II) protein family
CFBP6624_RS07395	COG0174	glutamine synthetase
CFBP6624_RS07425	COG0697	spore germination
CFBP6624_RS07440	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFBP6624_RS07450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFBP6624_RS07460	COG3668	Plasmid stabilization system
CFBP6624_RS07465	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFBP6624_RS07475	COG3153	acetyltransferase
CFBP6624_RS07480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP6624_RS07485	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFBP6624_RS07490	COG2186	Transcriptional regulator
CFBP6624_RS07500	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS07505	COG4603	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS07510	COG3845	ABC transporter
CFBP6624_RS07515	COG1183	phosphatidylcholine synthase activity
CFBP6624_RS07520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP6624_RS07525	COG0679	Auxin Efflux Carrier
CFBP6624_RS07530	COG0785	Cytochrome C biogenesis protein
CFBP6624_RS07560	COG0346	lactoylglutathione lyase activity
CFBP6624_RS07565	COG1278	Cold shock
CFBP6624_RS07630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP6624_RS07655	COG0798	PFAM Bile acid sodium symporter
CFBP6624_RS07665	COG0431	NADPH-dependent FMN reductase
CFBP6624_RS07690	COG1238	metal cluster binding
CFBP6624_RS07780	COG0577	efflux transmembrane transporter activity
CFBP6624_RS07780	COG1136	(ABC) transporter
CFBP6624_RS07785	COG1136	(ABC) transporter
CFBP6624_RS07785	COG0577	efflux transmembrane transporter activity
CFBP6624_RS07810	COG2151	metal-sulfur cluster biosynthetic enzyme
CFBP6624_RS07815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFBP6624_RS07820	COG0719	Fe-S assembly protein
CFBP6624_RS07825	COG0396	ATPase activity
CFBP6624_RS07835	COG0719	Fe-S assembly protein
CFBP6624_RS07840	COG1104	cysteine desulfurase activity
CFBP6624_RS07845	COG2945	thiolester hydrolase activity
CFBP6624_RS07855	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFBP6624_RS07860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFBP6624_RS07870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFBP6624_RS07875	COG2833	Protein of unknown function (DUF455)
CFBP6624_RS07880	COG0739	heme binding
CFBP6624_RS07885	COG0513	Belongs to the DEAD box helicase family
CFBP6624_RS07910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFBP6624_RS07920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP6624_RS07925	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP6624_RS07930	COG0047	phosphoribosylformylglycinamidine synthase activity
CFBP6624_RS07945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6624_RS07950	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP6624_RS07975	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CFBP6624_RS07980	COG2814	Major facilitator Superfamily
CFBP6624_RS07985	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6624_RS07990	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6624_RS07995	COG0037	tRNA processing
CFBP6624_RS08000	COG2066	Belongs to the glutaminase family
CFBP6624_RS08005	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFBP6624_RS08010	COG0861	Integral membrane protein TerC family
CFBP6624_RS08025	COG1280	lysine exporter protein (LysE YggA)
CFBP6624_RS08040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFBP6624_RS08045	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CFBP6624_RS08055	COG0538	isocitrate dehydrogenase activity
CFBP6624_RS08070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFBP6624_RS08080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFBP6624_RS08085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6624_RS08090	COG2313	pseudouridylate synthase activity
CFBP6624_RS08105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6624_RS08110	COG4215	(ABC) transporter
CFBP6624_RS08120	COG5425	PFAM Usg family protein
CFBP6624_RS08130	COG1522	sequence-specific DNA binding
CFBP6624_RS08135	COG1573	uracil-dna glycosylase
CFBP6624_RS08145	COG2202	Pas domain
CFBP6624_RS08145	COG2205	protein histidine kinase activity
CFBP6624_RS08155	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CFBP6624_RS08160	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CFBP6624_RS08175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP6624_RS08180	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS08185	COG1129	ABC transporter
CFBP6624_RS08195	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS08200	COG3959	Transketolase, thiamine diphosphate binding domain
CFBP6624_RS08205	COG3958	Transketolase
CFBP6624_RS08210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP6624_RS08215	COG2390	Transcriptional regulator
CFBP6624_RS08225	COG0842	Transport permease protein
CFBP6624_RS08230	COG1131	(ABC) transporter
CFBP6624_RS08235	COG0730	response to heat
CFBP6624_RS08235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6624_RS08250	COG0840	transmembrane signaling receptor activity
CFBP6624_RS08260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFBP6624_RS08265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6624_RS08280	COG0129	dihydroxy-acid dehydratase activity
CFBP6624_RS08285	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFBP6624_RS08290	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CFBP6624_RS08300	COG3739	integral membrane protein
CFBP6624_RS08305	COG0203	ribosomal protein L17
CFBP6624_RS08310	COG0202	RNA polymerase activity
CFBP6624_RS08315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFBP6624_RS08320	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFBP6624_RS08325	COG0563	adenylate kinase activity
CFBP6624_RS08330	COG0201	protein transport
CFBP6624_RS08335	COG0200	Binds to the 23S rRNA
CFBP6624_RS08340	COG1841	ribosomal large subunit assembly
CFBP6624_RS08345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFBP6624_RS08350	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFBP6624_RS08355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFBP6624_RS08360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFBP6624_RS08365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFBP6624_RS08370	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFBP6624_RS08375	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFBP6624_RS08380	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFBP6624_RS08385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFBP6624_RS08390	COG0255	Belongs to the universal ribosomal protein uL29 family
CFBP6624_RS08395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFBP6624_RS08400	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFBP6624_RS08405	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFBP6624_RS08410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFBP6624_RS08415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFBP6624_RS08420	COG0089	rRNA binding
CFBP6624_RS08425	COG0088	Forms part of the polypeptide exit tunnel
CFBP6624_RS08430	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFBP6624_RS08435	COG0051	transcription antitermination factor activity, RNA binding
CFBP6624_RS08440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP6624_RS08445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFBP6624_RS08450	COG0049	tRNA binding
CFBP6624_RS08455	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFBP6624_RS08475	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFBP6624_RS08480	COG0085	RNA polymerase activity
CFBP6624_RS08485	COG0222	ribosome binding
CFBP6624_RS08490	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFBP6624_RS08495	COG0081	regulation of translation
CFBP6624_RS08500	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFBP6624_RS08510	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFBP6624_RS08525	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP6624_RS08530	COG0861	Integral membrane protein TerC family
CFBP6624_RS08560	COG1132	(ABC) transporter
CFBP6624_RS08575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP6624_RS08580	COG1607	acyl-coa hydrolase
CFBP6624_RS08605	COG2910	NAD(P)H-binding
CFBP6624_RS08610	COG1733	regulation of RNA biosynthetic process
CFBP6624_RS08615	COG0454	-acetyltransferase
CFBP6624_RS08615	COG0456	acetyltransferase
CFBP6624_RS08625	COG0556	nucleotide-excision repair
CFBP6624_RS08635	COG2382	esterase
CFBP6624_RS08655	COG0484	heat shock protein binding
CFBP6624_RS08665	COG0582	viral genome integration into host DNA
CFBP6624_RS08790	COG3842	ATPase activity
CFBP6624_RS08800	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6624_RS08805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6624_RS08820	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFBP6624_RS08830	COG2207	Transcriptional regulator
CFBP6624_RS08835	COG1064	alcohol dehydrogenase
CFBP6624_RS08840	COG1252	NADH dehydrogenase
CFBP6624_RS08845	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFBP6624_RS08850	COG2197	response regulator
CFBP6624_RS08855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP6624_RS08860	COG0702	epimerase
CFBP6624_RS08900	COG0656	L-ascorbic acid biosynthetic process
CFBP6624_RS08915	COG0440	acetolactate synthase activity
CFBP6624_RS08920	COG0028	Belongs to the TPP enzyme family
CFBP6624_RS08930	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFBP6624_RS08935	COG0560	Phosphoserine phosphatase
CFBP6624_RS08945	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS08955	COG0330	HflC and HflK could
CFBP6624_RS08960	COG0330	HflC and HflK could
CFBP6624_RS08970	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFBP6624_RS09010	COG0277	FAD linked oxidase domain protein
CFBP6624_RS09015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6624_RS09050	COG0596	Alpha beta hydrolase
CFBP6624_RS09070	COG1335	isochorismatase
CFBP6624_RS09100	COG2264	protein methyltransferase activity
CFBP6624_RS09105	COG1999	signal sequence binding
CFBP6624_RS09110	COG0835	chemotaxis
CFBP6624_RS09125	COG0583	DNA-binding transcription factor activity
CFBP6624_RS09135	COG1247	-acetyltransferase
CFBP6624_RS09145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFBP6624_RS09155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP6624_RS09165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP6624_RS09170	COG0849	cell division
CFBP6624_RS09175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFBP6624_RS09180	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFBP6624_RS09185	COG0477	Major facilitator Superfamily
CFBP6624_RS09195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFBP6624_RS09200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFBP6624_RS09205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFBP6624_RS09215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFBP6624_RS09220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFBP6624_RS09230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFBP6624_RS09245	COG0275	rRNA processing
CFBP6624_RS09250	COG2001	Belongs to the MraZ family
CFBP6624_RS09260	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS09290	COG3023	N-Acetylmuramoyl-L-alanine amidase
CFBP6624_RS09320	COG4106	trans-aconitate 2-methyltransferase activity
CFBP6624_RS09340	COG2226	methyltransferase
CFBP6624_RS09350	COG2267	carboxylic ester hydrolase activity
CFBP6624_RS09355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP6624_RS09370	COG0251	oxidation-reduction process
CFBP6624_RS09385	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6624_RS09390	COG2814	Major facilitator Superfamily
CFBP6624_RS09415	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS09420	COG0174	glutamine synthetase
CFBP6624_RS09425	COG0531	amino acid
CFBP6624_RS09435	COG1737	Transcriptional regulator
CFBP6624_RS09460	COG3842	ATPase activity
CFBP6624_RS09480	COG0477	Major facilitator Superfamily
CFBP6624_RS09520	COG2968	Membrane
CFBP6624_RS09530	COG0432	Pfam Uncharacterised protein family UPF0047
CFBP6624_RS09550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP6624_RS09555	COG0358	DNA primase activity
CFBP6624_RS09575	COG0505	Belongs to the CarA family
CFBP6624_RS09580	COG0534	Mate efflux family protein
CFBP6624_RS09595	COG2321	neutral zinc metallopeptidase
CFBP6624_RS09610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFBP6624_RS09625	COG3706	GGDEF domain
CFBP6624_RS09630	COG1573	uracil-dna glycosylase
CFBP6624_RS09640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFBP6624_RS09650	COG1522	sequence-specific DNA binding
CFBP6624_RS09655	COG0492	ferredoxin-NADP+ reductase activity
CFBP6624_RS09660	COG0583	DNA-binding transcription factor activity
CFBP6624_RS09670	COG1902	pentaerythritol trinitrate reductase activity
CFBP6624_RS09700	COG0387	Pfam Sodium calcium exchanger
CFBP6624_RS09705	COG0436	Aminotransferase
CFBP6624_RS09710	COG2200	EAL domain
CFBP6624_RS09710	COG2199	diguanylate cyclase activity
CFBP6624_RS09730	COG1278	Cold shock
CFBP6624_RS09735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6624_RS09750	COG1846	Transcriptional regulator
CFBP6624_RS09755	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS09760	COG2205	protein histidine kinase activity
CFBP6624_RS09765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP6624_RS09785	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFBP6624_RS09795	COG1496	oxidoreductase activity
CFBP6624_RS09810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFBP6624_RS09830	COG0463	Glycosyl transferase, family 2
CFBP6624_RS09835	COG0840	transmembrane signaling receptor activity
CFBP6624_RS09840	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS09850	COG3300	MHYT domain
CFBP6624_RS09850	COG5001	Diguanylate cyclase
CFBP6624_RS09855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFBP6624_RS09860	COG5001	Diguanylate cyclase
CFBP6624_RS09870	COG0193	aminoacyl-tRNA hydrolase activity
CFBP6624_RS09880	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFBP6624_RS09885	COG0012	GTP binding
CFBP6624_RS09905	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFBP6624_RS09910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CFBP6624_RS09910	COG2857	Cytochrome c1
CFBP6624_RS09930	COG1132	(ABC) transporter
CFBP6624_RS09940	COG1132	(ABC) transporter
CFBP6624_RS09945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CFBP6624_RS09950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFBP6624_RS09965	COG0408	coproporphyrinogen oxidase activity
CFBP6624_RS09980	COG0617	tRNA 3'-terminal CCA addition
CFBP6624_RS09985	COG0494	nUDIX hydrolase
CFBP6624_RS09995	COG0714	Associated with various cellular activities
CFBP6624_RS10015	COG0454	-acetyltransferase
CFBP6624_RS10035	COG0477	Major facilitator Superfamily
CFBP6624_RS10045	COG0435	Glutathione S-transferase
CFBP6624_RS10050	COG0494	nUDIX hydrolase
CFBP6624_RS10060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFBP6624_RS10075	COG3135	benzoate transporter
CFBP6624_RS10100	COG0740	serine-type endopeptidase activity
CFBP6624_RS10115	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFBP6624_RS10120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFBP6624_RS10145	COG4175	Glycine betaine
CFBP6624_RS10160	COG1435	thymidine kinase activity
CFBP6624_RS10180	COG2862	Uncharacterized protein family, UPF0114
CFBP6624_RS10185	COG4771	TonB-dependent receptor
CFBP6624_RS10185	COG1629	transport
CFBP6624_RS10195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFBP6624_RS10195	COG0512	Glutamine amidotransferase of anthranilate synthase
CFBP6624_RS10210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP6624_RS10225	COG0366	Alpha amylase catalytic
CFBP6624_RS10230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6624_RS10250	COG1160	GTP binding
CFBP6624_RS10270	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CFBP6624_RS10280	COG0024	Methionine aminopeptidase
CFBP6624_RS10290	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS10310	COG0583	DNA-binding transcription factor activity
CFBP6624_RS10325	COG0402	S-adenosylhomocysteine deaminase activity
CFBP6624_RS10340	COG1304	FMN binding
CFBP6624_RS10350	COG1309	transcriptional regulator
CFBP6624_RS10355	COG1686	Belongs to the peptidase S11 family
CFBP6624_RS10365	COG2351	hydroxyisourate hydrolase activity
CFBP6624_RS10370	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CFBP6624_RS10395	COG3195	allantoin biosynthetic process
CFBP6624_RS10395	COG3648	Uricase
CFBP6624_RS10405	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP6624_RS10410	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFBP6624_RS10410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS10415	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFBP6624_RS10415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS10420	COG0784	Response regulator, receiver
CFBP6624_RS10420	COG2205	protein histidine kinase activity
CFBP6624_RS10420	COG5002	protein histidine kinase activity
CFBP6624_RS10425	COG0513	Belongs to the DEAD box helicase family
CFBP6624_RS10435	COG2259	Doxx family
CFBP6624_RS10440	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6624_RS10450	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP6624_RS10460	COG1305	Transglutaminase-like
CFBP6624_RS10480	COG0588	phosphoglycerate mutase activity
CFBP6624_RS10490	COG4214	carbohydrate transport
CFBP6624_RS10500	COG4213	ABC transporter substrate-binding protein
CFBP6624_RS10540	COG0840	transmembrane signaling receptor activity
CFBP6624_RS10545	COG2814	Major facilitator Superfamily
CFBP6624_RS10575	COG1215	transferase activity, transferring glycosyl groups
CFBP6624_RS10590	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CFBP6624_RS10610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP6624_RS10615	COG2346	COG2346, Truncated hemoglobins
CFBP6624_RS10635	COG1309	transcriptional regulator
CFBP6624_RS10650	COG2852	Protein conserved in bacteria
CFBP6624_RS10660	COG0494	nUDIX hydrolase
CFBP6624_RS10675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6624_RS10680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6624_RS10705	COG1234	tRNA 3'-trailer cleavage
CFBP6624_RS10710	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFBP6624_RS10715	COG0830	nickel cation binding
CFBP6624_RS10720	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CFBP6624_RS10735	COG0804	urea catabolic process
CFBP6624_RS10745	COG3755	Protein conserved in bacteria
CFBP6624_RS10755	COG0832	Belongs to the urease beta subunit family
CFBP6624_RS10760	COG3813	Protein conserved in bacteria
CFBP6624_RS10765	COG0831	urea catabolic process
CFBP6624_RS10770	COG0829	nickel cation binding
CFBP6624_RS10800	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS10820	COG0174	glutamine synthetase
CFBP6624_RS10825	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS10830	COG5002	protein histidine kinase activity
CFBP6624_RS10830	COG2198	Histidine kinase
CFBP6624_RS10830	COG0784	Response regulator, receiver
CFBP6624_RS10845	COG0726	polysaccharide deacetylase
CFBP6624_RS10880	COG1218	3'(2'),5'-bisphosphate nucleotidase
CFBP6624_RS10960	COG0564	pseudouridine synthase activity
CFBP6624_RS10975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP6624_RS10985	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFBP6624_RS11015	COG0346	lactoylglutathione lyase activity
CFBP6624_RS11025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFBP6624_RS11035	COG2832	Protein of unknown function (DUF454)
CFBP6624_RS11040	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFBP6624_RS11045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6624_RS11050	COG4558	Periplasmic binding protein
CFBP6624_RS11060	COG3721	Heme iron utilization protein
CFBP6624_RS11080	COG3657	addiction module killer protein
CFBP6624_RS11090	COG2205	protein histidine kinase activity
CFBP6624_RS11130	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6624_RS11135	COG4605	iron ion homeostasis
CFBP6624_RS11140	COG4604	ABC transporter, ATP-binding protein
CFBP6624_RS11145	COG0783	Belongs to the Dps family
CFBP6624_RS11160	COG0656	L-ascorbic acid biosynthetic process
CFBP6624_RS11165	COG2814	Major facilitator Superfamily
CFBP6624_RS11175	COG0583	DNA-binding transcription factor activity
CFBP6624_RS11180	COG0657	acetylesterase activity
CFBP6624_RS11185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6624_RS11205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFBP6624_RS11210	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CFBP6624_RS11215	COG0288	reversible hydration of carbon dioxide
CFBP6624_RS11225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFBP6624_RS11245	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CFBP6624_RS11250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP6624_RS11255	COG0778	Nitroreductase
CFBP6624_RS11260	COG2267	carboxylic ester hydrolase activity
CFBP6624_RS11265	COG0251	oxidation-reduction process
CFBP6624_RS11270	COG1335	isochorismatase
CFBP6624_RS11275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS11285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6624_RS11300	COG1175	transmembrane transport
CFBP6624_RS11305	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS11310	COG3842	ATPase activity
CFBP6624_RS11315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6624_RS11340	COG4608	Belongs to the ABC transporter superfamily
CFBP6624_RS11345	COG0444	Belongs to the ABC transporter superfamily
CFBP6624_RS11350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS11355	COG0601	transmembrane transport
CFBP6624_RS11415	COG2159	amidohydrolase
CFBP6624_RS11420	COG1960	acyl-CoA dehydrogenase activity
CFBP6624_RS11450	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS11460	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP6624_RS11460	COG1902	pentaerythritol trinitrate reductase activity
CFBP6624_RS11475	COG4232	protein-disulfide reductase activity
CFBP6624_RS11480	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFBP6624_RS11480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFBP6624_RS11490	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6624_RS11490	COG1388	LysM domain
CFBP6624_RS11500	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP6624_RS11510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFBP6624_RS11515	COG1177	transmembrane transport
CFBP6624_RS11520	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP6624_RS11525	COG3842	ATPase activity
CFBP6624_RS11570	COG3038	cytochrome b561
CFBP6624_RS11610	COG1505	serine-type exopeptidase activity
CFBP6624_RS11625	COG1733	regulation of RNA biosynthetic process
CFBP6624_RS11645	COG1335	isochorismatase
CFBP6624_RS11665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP6624_RS11665	COG0475	glutathione-regulated potassium exporter activity
CFBP6624_RS11690	COG0251	oxidation-reduction process
CFBP6624_RS11695	COG1741	Belongs to the pirin family
CFBP6624_RS11710	COG0300	oxidoreductase activity
CFBP6624_RS11760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP6624_RS11765	COG1309	transcriptional regulator
CFBP6624_RS11770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6624_RS11775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6624_RS11785	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFBP6624_RS11790	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CFBP6624_RS11810	COG0583	DNA-binding transcription factor activity
CFBP6624_RS11815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS11820	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFBP6624_RS11825	COG4149	molybdate abc transporter
CFBP6624_RS11830	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CFBP6624_RS11840	COG3191	aminopeptidase activity
CFBP6624_RS11845	COG2022	thiamine diphosphate biosynthetic process
CFBP6624_RS11860	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFBP6624_RS11865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6624_RS11875	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP6624_RS11900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP6624_RS11945	COG4166	transmembrane transport
CFBP6624_RS11950	COG0601	transmembrane transport
CFBP6624_RS11955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS11965	COG0438	transferase activity, transferring glycosyl groups
CFBP6624_RS11970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFBP6624_RS11975	COG3142	Participates in the control of copper homeostasis
CFBP6624_RS11980	COG2814	Major facilitator Superfamily
CFBP6624_RS11995	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS12000	COG1737	Transcriptional regulator
CFBP6624_RS12010	COG3842	ATPase activity
CFBP6624_RS12020	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS12040	COG2188	Transcriptional regulator
CFBP6624_RS12045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP6624_RS12050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFBP6624_RS12055	COG1940	carbohydrate kinase activity
CFBP6624_RS12065	COG0671	phosphoesterase, PA-phosphatase related
CFBP6624_RS12070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFBP6624_RS12075	COG0156	8-amino-7-oxononanoate synthase activity
CFBP6624_RS12085	COG0729	surface antigen
CFBP6624_RS12095	COG0835	chemotaxis
CFBP6624_RS12105	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFBP6624_RS12110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFBP6624_RS12115	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFBP6624_RS12120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFBP6624_RS12125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFBP6624_RS12130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFBP6624_RS12145	COG4974	Belongs to the 'phage' integrase family
CFBP6624_RS12170	COG1280	lysine exporter protein (LysE YggA)
CFBP6624_RS12180	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP6624_RS12190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFBP6624_RS12195	COG0045	succinate-CoA ligase (ADP-forming) activity
CFBP6624_RS12200	COG0039	L-malate dehydrogenase activity
CFBP6624_RS12205	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFBP6624_RS12245	COG2264	protein methyltransferase activity
CFBP6624_RS12260	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFBP6624_RS12265	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFBP6624_RS12270	COG0181	hydroxymethylbilane synthase activity
CFBP6624_RS12305	COG1872	DUF167
CFBP6624_RS12310	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFBP6624_RS12325	COG1217	gtp-binding protein TYPA
CFBP6624_RS12330	COG0339	signal peptide processing
CFBP6624_RS12340	COG1846	Transcriptional regulator
CFBP6624_RS12350	COG0137	argininosuccinate synthase activity
CFBP6624_RS12355	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS12360	COG1280	lysine exporter protein (LysE YggA)
CFBP6624_RS12365	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFBP6624_RS12370	COG4120	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS12380	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CFBP6624_RS12395	COG2154	pterin-4-alpha-carbinolamine dehydratase
CFBP6624_RS12400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFBP6624_RS12405	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CFBP6624_RS12415	COG4181	ATPase activity
CFBP6624_RS12425	COG0670	Belongs to the BI1 family
CFBP6624_RS12440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFBP6624_RS12445	COG4133	protoheme IX ABC transporter activity
CFBP6624_RS12455	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP6624_RS12460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP6624_RS12485	COG2917	probably involved in intracellular septation
CFBP6624_RS12490	COG0552	protein localization to endoplasmic reticulum
CFBP6624_RS12495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP6624_RS12500	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFBP6624_RS12515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFBP6624_RS12520	COG0287	Prephenate dehydrogenase
CFBP6624_RS12520	COG1605	Chorismate mutase
CFBP6624_RS12525	COG0228	four-way junction DNA binding
CFBP6624_RS12530	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFBP6624_RS12535	COG0336	Belongs to the RNA methyltransferase TrmD family
CFBP6624_RS12545	COG0335	large ribosomal subunit rRNA binding
CFBP6624_RS12555	COG0765	amino acid transport
CFBP6624_RS12570	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFBP6624_RS12585	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFBP6624_RS12605	COG0488	(ABC) transporter
CFBP6624_RS12615	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CFBP6624_RS12625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFBP6624_RS12630	COG0142	geranyltranstransferase activity
CFBP6624_RS12635	COG2885	chlorophyll binding
CFBP6624_RS12640	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFBP6624_RS12645	COG2223	nitrite transmembrane transporter activity
CFBP6624_RS12650	COG1349	DNA-binding transcription factor activity
CFBP6624_RS12655	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFBP6624_RS12660	COG2197	response regulator
CFBP6624_RS12665	COG1132	(ABC) transporter
CFBP6624_RS12675	COG3459	Glycosyltransferase 36 associated
CFBP6624_RS12680	COG1473	amidohydrolase
CFBP6624_RS12690	COG0579	oxidoreductase
CFBP6624_RS12700	COG0129	dihydroxy-acid dehydratase activity
CFBP6624_RS12705	COG2084	Dehydrogenase
CFBP6624_RS12710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6624_RS12715	COG0277	FAD linked oxidase domain protein
CFBP6624_RS12720	COG2186	Transcriptional regulator
CFBP6624_RS12730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP6624_RS12735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6624_RS12740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6624_RS12745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP6624_RS12755	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFBP6624_RS12760	COG0495	leucyl-tRNA aminoacylation
CFBP6624_RS12775	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFBP6624_RS12780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFBP6624_RS12795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP6624_RS12800	COG1946	Acyl-CoA thioesterase
CFBP6624_RS12805	COG0347	Belongs to the P(II) protein family
CFBP6624_RS12810	COG0004	ammonium transporteR
CFBP6624_RS12815	COG1674	ftsk spoiiie
CFBP6624_RS12820	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CFBP6624_RS12835	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS12845	COG1329	Transcriptional regulator
CFBP6624_RS12850	COG2902	Dehydrogenase
CFBP6624_RS12855	COG2270	Major facilitator Superfamily
CFBP6624_RS12870	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS12885	COG0494	nUDIX hydrolase
CFBP6624_RS12895	COG0793	Belongs to the peptidase S41A family
CFBP6624_RS12905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFBP6624_RS12910	COG0799	negative regulation of ribosome biogenesis
CFBP6624_RS12915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFBP6624_RS12920	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFBP6624_RS12925	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFBP6624_RS12930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFBP6624_RS12945	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFBP6624_RS12950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFBP6624_RS12975	COG0066	3-isopropylmalate dehydratase activity
CFBP6624_RS12980	COG0473	3-isopropylmalate dehydrogenase activity
CFBP6624_RS12985	COG1858	cytochrome C peroxidase
CFBP6624_RS12990	COG1797	cobyrinic acid a,c-diamide synthase activity
CFBP6624_RS12995	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP6624_RS12995	COG1648	precorrin-2 dehydrogenase activity
CFBP6624_RS13000	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CFBP6624_RS13065	COG1492	cobalamin metabolic process
CFBP6624_RS13070	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CFBP6624_RS13080	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6624_RS13085	COG3254	rhamnose metabolic process
CFBP6624_RS13095	COG1063	alcohol dehydrogenase
CFBP6624_RS13115	COG4214	carbohydrate transport
CFBP6624_RS13120	COG1129	ABC transporter
CFBP6624_RS13125	COG2186	Transcriptional regulator
CFBP6624_RS13130	COG2721	sulfolactate sulfo-lyase activity
CFBP6624_RS13135	COG0138	bifunctional purine biosynthesis protein purh
CFBP6624_RS13145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFBP6624_RS13145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFBP6624_RS13150	COG0501	Belongs to the peptidase M48B family
CFBP6624_RS13170	COG0357	Ribosomal RNA small subunit methyltransferase G
CFBP6624_RS13175	COG0445	tRNA wobble uridine modification
CFBP6624_RS13180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFBP6624_RS13185	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFBP6624_RS13190	COG1981	membrane
CFBP6624_RS13195	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFBP6624_RS13205	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CFBP6624_RS13210	COG0424	maF-like protein
CFBP6624_RS13215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP6624_RS13220	COG0237	dephospho-CoA kinase activity
CFBP6624_RS13230	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CFBP6624_RS13235	COG3030	protein affecting phage T7 exclusion by the F plasmid
CFBP6624_RS13245	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CFBP6624_RS13270	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFBP6624_RS13285	COG0135	phosphoribosylanthranilate isomerase activity
CFBP6624_RS13290	COG0133	tryptophan synthase activity
CFBP6624_RS13295	COG0159	tryptophan synthase activity
CFBP6624_RS13300	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFBP6624_RS13305	COG0285	dihydrofolate synthase activity
CFBP6624_RS13325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFBP6624_RS13335	COG2205	protein histidine kinase activity
CFBP6624_RS13345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CFBP6624_RS13350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP6624_RS13355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFBP6624_RS13355	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP6624_RS13360	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFBP6624_RS13365	COG0642	Histidine kinase
CFBP6624_RS13370	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS13375	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CFBP6624_RS13385	COG1652	LysM domain
CFBP6624_RS13390	COG1072	(Pantothenic acid kinase))
CFBP6624_RS13395	COG0140	phosphoribosyl-ATP diphosphatase activity
CFBP6624_RS13400	COG0107	imidazoleglycerol-phosphate synthase activity
CFBP6624_RS13405	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFBP6624_RS13410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFBP6624_RS13420	COG0131	Imidazoleglycerol-phosphate dehydratase
CFBP6624_RS13425	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFBP6624_RS13430	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFBP6624_RS13440	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFBP6624_RS13455	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CFBP6624_RS13465	COG1643	Atp-dependent helicase
CFBP6624_RS13510	COG0514	ATP-dependent DNA helicase (RecQ)
CFBP6624_RS13535	COG1072	(Pantothenic acid kinase))
CFBP6624_RS13545	COG1780	Probably involved in ribonucleotide reductase function
CFBP6624_RS13555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFBP6624_RS13565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFBP6624_RS13590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6624_RS13600	COG2813	Specifically methylates the guanine in position
CFBP6624_RS13605	COG1185	polyribonucleotide nucleotidyltransferase activity
CFBP6624_RS13610	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFBP6624_RS13615	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFBP6624_RS13620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFBP6624_RS13625	COG3064	Membrane
CFBP6624_RS13625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFBP6624_RS13640	COG0779	Required for maturation of 30S ribosomal subunits
CFBP6624_RS13645	COG2814	Major facilitator Superfamily
CFBP6624_RS13650	COG2951	lytic endotransglycosylase activity
CFBP6624_RS13655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFBP6624_RS13665	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFBP6624_RS13670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFBP6624_RS13685	COG2816	NAD+ diphosphatase activity
CFBP6624_RS13690	COG1605	Chorismate mutase
CFBP6624_RS13690	COG0077	Prephenate dehydratase
CFBP6624_RS13695	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CFBP6624_RS13700	COG3474	cytochrome
CFBP6624_RS13710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP6624_RS13715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFBP6624_RS13725	COG1278	Cold shock
CFBP6624_RS13735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP6624_RS13750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP6624_RS13750	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP6624_RS13760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CFBP6624_RS13795	COG2900	Belongs to the SlyX family
CFBP6624_RS13805	COG0484	heat shock protein binding
CFBP6624_RS13810	COG0443	Heat shock 70 kDa protein
CFBP6624_RS13865	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP6624_RS13870	COG1744	ABC transporter substrate-binding protein PnrA-like
CFBP6624_RS13875	COG3845	ABC transporter
CFBP6624_RS13880	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS13885	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS13890	COG0295	cytidine deaminase activity
CFBP6624_RS13895	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFBP6624_RS13900	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFBP6624_RS13905	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CFBP6624_RS13915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFBP6624_RS13920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFBP6624_RS13925	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFBP6624_RS13935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFBP6624_RS13940	COG1845	cytochrome c oxidase, subunit III
CFBP6624_RS13945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP6624_RS13955	COG0477	Major facilitator Superfamily
CFBP6624_RS13960	COG0069	glutamate synthase activity
CFBP6624_RS13960	COG0067	glutamate synthase
CFBP6624_RS13960	COG0070	glutamate synthase
CFBP6624_RS13965	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CFBP6624_RS13980	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP6624_RS13990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP6624_RS14025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6624_RS14045	COG0848	biopolymer transport protein
CFBP6624_RS14055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP6624_RS14070	COG4977	sequence-specific DNA binding
CFBP6624_RS14075	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP6624_RS14080	COG3454	Phosphonate metabolism
CFBP6624_RS14085	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP6624_RS14090	COG3639	organic phosphonate transmembrane transporter activity
CFBP6624_RS14095	COG3639	organic phosphonate transmembrane transporter activity
CFBP6624_RS14100	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CFBP6624_RS14105	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFBP6624_RS14115	COG4778	phosphonate C-P lyase system protein PhnL
CFBP6624_RS14120	COG4107	phosphonate C-P lyase system protein PhnK
CFBP6624_RS14125	COG3627	carbon phosphorus lyase activity
CFBP6624_RS14130	COG3626	phosphonate metabolism
CFBP6624_RS14135	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CFBP6624_RS14140	COG3624	Phosphonate C-P lyase system protein PhnG
CFBP6624_RS14145	COG2188	Transcriptional regulator
CFBP6624_RS14150	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFBP6624_RS14155	COG0837	glucose binding
CFBP6624_RS14160	COG1803	Methylglyoxal synthase
CFBP6624_RS14165	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CFBP6624_RS14170	COG4166	transmembrane transport
CFBP6624_RS14175	COG4174	ABC transporter (Permease)
CFBP6624_RS14180	COG4239	(ABC) transporter, permease
CFBP6624_RS14185	COG4172	Belongs to the ABC transporter superfamily
CFBP6624_RS14190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS14195	COG0174	glutamine synthetase
CFBP6624_RS14200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS14205	COG3265	gluconokinase activity
CFBP6624_RS14210	COG1174	glycine betaine transport
CFBP6624_RS14215	COG1125	glycine betaine transport
CFBP6624_RS14220	COG1174	glycine betaine transport
CFBP6624_RS14225	COG1732	Glycine betaine
CFBP6624_RS14235	COG1959	2 iron, 2 sulfur cluster binding
CFBP6624_RS14240	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6624_RS14250	COG4269	membrane
CFBP6624_RS14270	COG0697	spore germination
CFBP6624_RS14295	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFBP6624_RS14300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP6624_RS14335	COG4964	Belongs to the GSP D family
CFBP6624_RS14385	COG3422	double-strand break repair
CFBP6624_RS14390	COG3757	hydrolase, family 25
CFBP6624_RS14395	COG0697	spore germination
CFBP6624_RS14400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6624_RS14430	COG0481	GTPase activity
CFBP6624_RS14435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP6624_RS14465	COG2169	Transcriptional regulator
CFBP6624_RS14465	COG1917	Cupin 2, conserved barrel domain protein
CFBP6624_RS14470	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP6624_RS14495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFBP6624_RS14500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFBP6624_RS14505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFBP6624_RS14515	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFBP6624_RS14520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP6624_RS14520	COG0072	phenylalanine-tRNA ligase activity
CFBP6624_RS14525	COG0667	Aldo Keto reductase
CFBP6624_RS14545	COG4977	sequence-specific DNA binding
CFBP6624_RS14570	COG1570	exodeoxyribonuclease VII activity
CFBP6624_RS14575	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6624_RS14585	COG1846	Transcriptional regulator
CFBP6624_RS14590	COG0697	spore germination
CFBP6624_RS14595	COG2309	aminopeptidase activity
CFBP6624_RS14605	COG1393	Belongs to the ArsC family
CFBP6624_RS14625	COG1309	transcriptional regulator
CFBP6624_RS14635	COG0519	Catalyzes the synthesis of GMP from XMP
CFBP6624_RS14635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFBP6624_RS14650	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CFBP6624_RS14680	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CFBP6624_RS14690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFBP6624_RS14700	COG1968	undecaprenyl-diphosphatase activity
CFBP6624_RS14725	COG0284	orotidine-5'-phosphate decarboxylase activity
CFBP6624_RS14735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFBP6624_RS14745	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFBP6624_RS14750	COG0792	nuclease activity
CFBP6624_RS14765	COG1175	transmembrane transport
CFBP6624_RS14770	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS14775	COG3842	ATPase activity
CFBP6624_RS14785	COG0189	ligase activity
CFBP6624_RS14795	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFBP6624_RS14800	COG1280	lysine exporter protein (LysE YggA)
CFBP6624_RS14805	COG0756	dUTP diphosphatase activity
CFBP6624_RS14810	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFBP6624_RS14815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFBP6624_RS14830	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFBP6624_RS14835	COG2226	methyltransferase
CFBP6624_RS14840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFBP6624_RS14845	COG1024	Enoyl-CoA hydratase
CFBP6624_RS14850	COG0268	Binds directly to 16S ribosomal RNA
CFBP6624_RS14890	COG0640	Transcriptional regulator
CFBP6624_RS14945	COG3842	ATPase activity
CFBP6624_RS14950	COG1175	transmembrane transport
CFBP6624_RS14975	COG1049	propionate catabolic process, 2-methylcitrate cycle
CFBP6624_RS14980	COG0840	transmembrane signaling receptor activity
CFBP6624_RS14995	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS15000	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP6624_RS15010	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6624_RS15015	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS15020	COG1414	Transcriptional regulator
CFBP6624_RS15025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFBP6624_RS15030	COG3842	ATPase activity
CFBP6624_RS15035	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS15040	COG1175	transmembrane transport
CFBP6624_RS15050	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6624_RS15055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6624_RS15060	COG3734	2-keto-3-deoxy-galactonokinase
CFBP6624_RS15065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6624_RS15080	COG2828	Protein conserved in bacteria
CFBP6624_RS15085	COG0583	DNA-binding transcription factor activity
CFBP6624_RS15090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFBP6624_RS15095	COG0583	DNA-binding transcription factor activity
CFBP6624_RS15100	COG2233	PERMEase
CFBP6624_RS15105	COG5001	Diguanylate cyclase
CFBP6624_RS15175	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CFBP6624_RS15205	COG1653	transport
CFBP6624_RS15210	COG1175	transmembrane transport
CFBP6624_RS15215	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS15220	COG3842	ATPase activity
CFBP6624_RS15225	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS15230	COG1175	transmembrane transport
CFBP6624_RS15260	COG1609	Transcriptional regulator
CFBP6624_RS15270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6624_RS15275	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6624_RS15280	COG3842	ATPase activity
CFBP6624_RS15285	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS15290	COG1175	transmembrane transport
CFBP6624_RS15295	COG1653	transport
CFBP6624_RS15300	COG1309	transcriptional regulator
CFBP6624_RS15305	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS15320	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS15325	COG1278	Cold shock
CFBP6624_RS15335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP6624_RS15360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6624_RS15375	COG1629	transport
CFBP6624_RS15380	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFBP6624_RS15385	COG3618	amidohydrolase
CFBP6624_RS15390	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6624_RS15395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6624_RS15400	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS15405	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CFBP6624_RS15410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6624_RS15415	COG2186	Transcriptional regulator
CFBP6624_RS15460	COG4977	sequence-specific DNA binding
CFBP6624_RS15465	COG2223	nitrite transmembrane transporter activity
CFBP6624_RS15470	COG0583	DNA-binding transcription factor activity
CFBP6624_RS15475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6624_RS15485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6624_RS15490	COG2084	Dehydrogenase
CFBP6624_RS15505	COG1609	Transcriptional regulator
CFBP6624_RS15510	COG1063	alcohol dehydrogenase
CFBP6624_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS15525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6624_RS15530	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CFBP6624_RS15535	COG1175	transmembrane transport
CFBP6624_RS15540	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS15555	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS15560	COG1175	transmembrane transport
CFBP6624_RS15565	COG2182	Extracellular solute-binding protein
CFBP6624_RS15570	COG0626	cystathionine gamma-synthase activity
CFBP6624_RS15580	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFBP6624_RS15590	COG1121	(ABC) transporter
CFBP6624_RS15595	COG0523	cobalamin synthesis protein
CFBP6624_RS15610	COG2226	methyltransferase
CFBP6624_RS15615	COG0587	DNA-directed DNA polymerase activity
CFBP6624_RS15645	COG5001	Diguanylate cyclase
CFBP6624_RS15645	COG3300	MHYT domain
CFBP6624_RS15655	COG2011	ABC-type metal ion transport system permease component
CFBP6624_RS15660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFBP6624_RS15705	COG0583	DNA-binding transcription factor activity
CFBP6624_RS15710	COG1879	ABC-type sugar transport system periplasmic component
CFBP6624_RS15715	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS15720	COG1129	ABC transporter
CFBP6624_RS15730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6624_RS15735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6624_RS15745	COG3257	ureidoglycine aminohydrolase activity
CFBP6624_RS15755	COG5001	Diguanylate cyclase
CFBP6624_RS15760	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP6624_RS15770	COG0747	negative chemotaxis
CFBP6624_RS15775	COG0601	transmembrane transport
CFBP6624_RS15780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS15790	COG4608	Belongs to the ABC transporter superfamily
CFBP6624_RS15795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CFBP6624_RS15810	COG0346	lactoylglutathione lyase activity
CFBP6624_RS15820	COG0129	dihydroxy-acid dehydratase activity
CFBP6624_RS15825	COG1879	ABC-type sugar transport system periplasmic component
CFBP6624_RS15830	COG1129	ABC transporter
CFBP6624_RS15835	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS15840	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS15845	COG2186	Transcriptional regulator
CFBP6624_RS15860	COG0523	cobalamin synthesis protein
CFBP6624_RS15865	COG1653	transport
CFBP6624_RS15870	COG1175	transmembrane transport
CFBP6624_RS15875	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS15880	COG3842	ATPase activity
CFBP6624_RS15890	COG3047	cAMP biosynthetic process
CFBP6624_RS15895	COG2115	Belongs to the xylose isomerase family
CFBP6624_RS15905	COG1070	Carbohydrate kinase
CFBP6624_RS15910	COG1609	Transcriptional regulator
CFBP6624_RS15925	COG1309	transcriptional regulator
CFBP6624_RS15930	COG1253	flavin adenine dinucleotide binding
CFBP6624_RS15935	COG3273	potassium ion transport
CFBP6624_RS15935	COG0471	metal ion transport
CFBP6624_RS15940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP6624_RS15950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFBP6624_RS15960	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFBP6624_RS15965	COG1121	(ABC) transporter
CFBP6624_RS15970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP6624_RS15975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP6624_RS15985	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS15990	COG1414	Transcriptional regulator
CFBP6624_RS15995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFBP6624_RS16015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP6624_RS16020	COG2186	Transcriptional regulator
CFBP6624_RS16025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6624_RS16035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6624_RS16040	COG1063	alcohol dehydrogenase
CFBP6624_RS16045	COG1312	Catalyzes the dehydration of D-mannonate
CFBP6624_RS16065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6624_RS16070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6624_RS16070	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP6624_RS16075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS16090	COG0625	glutathione transferase activity
CFBP6624_RS16095	COG4172	Belongs to the ABC transporter superfamily
CFBP6624_RS16100	COG1921	L-seryl-tRNASec selenium transferase activity
CFBP6624_RS16115	COG3964	amidohydrolase
CFBP6624_RS16125	COG0601	transmembrane transport
CFBP6624_RS16130	COG0747	negative chemotaxis
CFBP6624_RS16135	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP6624_RS16140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6624_RS16170	COG4989	oxidoreductase activity
CFBP6624_RS16185	COG3842	ATPase activity
CFBP6624_RS16190	COG1653	transport
CFBP6624_RS16195	COG1175	transmembrane transport
CFBP6624_RS16200	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS16205	COG1501	Belongs to the glycosyl hydrolase 31 family
CFBP6624_RS16235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6624_RS16270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6624_RS16275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6624_RS16280	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CFBP6624_RS16285	COG0352	thiamine-phosphate diphosphorylase activity
CFBP6624_RS16290	COG0351	phosphomethylpyrimidine kinase
CFBP6624_RS16300	COG1522	sequence-specific DNA binding
CFBP6624_RS16305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP6624_RS16310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS16320	COG2204	response regulator
CFBP6624_RS16325	COG4191	Histidine kinase
CFBP6624_RS16330	COG1301	dicarboxylic acid transport
CFBP6624_RS16340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6624_RS16345	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS16355	COG1473	amidohydrolase
CFBP6624_RS16375	COG1215	transferase activity, transferring glycosyl groups
CFBP6624_RS16385	COG2942	2-epimerase
CFBP6624_RS16405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFBP6624_RS16410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6624_RS16450	COG3307	-O-antigen
CFBP6624_RS16455	COG1596	polysaccharide export
CFBP6624_RS16460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFBP6624_RS16470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6624_RS16475	COG0840	transmembrane signaling receptor activity
CFBP6624_RS16480	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6624_RS16490	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS16500	COG2094	Belongs to the DNA glycosylase MPG family
CFBP6624_RS16515	COG1609	Transcriptional regulator
CFBP6624_RS16520	COG1653	transport
CFBP6624_RS16545	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS16550	COG0602	queuosine metabolic process
CFBP6624_RS16555	COG0720	synthase
CFBP6624_RS16560	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFBP6624_RS16565	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS16580	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS16585	COG1175	transmembrane transport
CFBP6624_RS16605	COG0281	malic enzyme
CFBP6624_RS16605	COG0280	phosphate acetyltransferase
CFBP6624_RS16620	COG0765	amino acid transport
CFBP6624_RS16625	COG1126	abc transporter atp-binding protein
CFBP6624_RS16630	COG2079	MmgE PrpD family protein
CFBP6624_RS16635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS16645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS16670	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP6624_RS16675	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFBP6624_RS16680	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS16685	COG1129	ABC transporter
CFBP6624_RS16700	COG1473	amidohydrolase
CFBP6624_RS16725	COG0601	transmembrane transport
CFBP6624_RS16730	COG0583	DNA-binding transcription factor activity
CFBP6624_RS16735	COG1446	asparaginase
CFBP6624_RS16750	COG0747	negative chemotaxis
CFBP6624_RS16770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS16775	COG0601	transmembrane transport
CFBP6624_RS16780	COG2197	response regulator
CFBP6624_RS16785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP6624_RS16790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6624_RS16805	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS16810	COG1175	transmembrane transport
CFBP6624_RS16820	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS16825	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS16845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6624_RS16850	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP6624_RS16870	COG1595	DNA-templated transcription, initiation
CFBP6624_RS16875	COG1120	ATPase activity
CFBP6624_RS16880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6624_RS16895	COG2226	methyltransferase
CFBP6624_RS16905	COG1120	ATPase activity
CFBP6624_RS16910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6624_RS16925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP6624_RS16930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP6624_RS16940	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS16945	COG0473	3-isopropylmalate dehydrogenase activity
CFBP6624_RS16950	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS16955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS16990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS16995	COG4172	Belongs to the ABC transporter superfamily
CFBP6624_RS17000	COG1522	sequence-specific DNA binding
CFBP6624_RS17005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS17015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6624_RS17020	COG1126	abc transporter atp-binding protein
CFBP6624_RS17030	COG1473	amidohydrolase
CFBP6624_RS17035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS17040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS17045	COG1959	2 iron, 2 sulfur cluster binding
CFBP6624_RS17055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP6624_RS17085	COG1960	acyl-CoA dehydrogenase activity
CFBP6624_RS17120	COG0667	Aldo Keto reductase
CFBP6624_RS17130	COG0583	DNA-binding transcription factor activity
CFBP6624_RS17135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS17150	COG0747	negative chemotaxis
CFBP6624_RS17155	COG1473	amidohydrolase
CFBP6624_RS17160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS17180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS17200	COG4608	Belongs to the ABC transporter superfamily
CFBP6624_RS17205	COG0444	Belongs to the ABC transporter superfamily
CFBP6624_RS17215	COG0601	transmembrane transport
CFBP6624_RS17230	COG2186	Transcriptional regulator
CFBP6624_RS17235	COG3453	Protein conserved in bacteria
CFBP6624_RS17235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6624_RS17240	COG0640	Transcriptional regulator
CFBP6624_RS17250	COG2391	methyltransferase activity
CFBP6624_RS17255	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFBP6624_RS17270	COG0022	dehydrogenase e1 component
CFBP6624_RS17280	COG1960	acyl-CoA dehydrogenase activity
CFBP6624_RS17285	COG0183	Belongs to the thiolase family
CFBP6624_RS17295	COG1960	acyl-CoA dehydrogenase activity
CFBP6624_RS17300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP6624_RS17315	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CFBP6624_RS17320	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFBP6624_RS17325	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CFBP6624_RS17330	COG4952	isomerase
CFBP6624_RS17335	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS17335	COG3347	Dehydrogenase
CFBP6624_RS17340	COG1349	DNA-binding transcription factor activity
CFBP6624_RS17355	COG1129	ABC transporter
CFBP6624_RS17360	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS17370	COG3254	rhamnose metabolic process
CFBP6624_RS17385	COG2264	protein methyltransferase activity
CFBP6624_RS17390	COG5001	Diguanylate cyclase
CFBP6624_RS17410	COG4335	DNA alkylation repair
CFBP6624_RS17415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP6624_RS17420	COG4208	sulfate ABC transporter
CFBP6624_RS17435	COG1024	Enoyl-CoA hydratase
CFBP6624_RS17450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP6624_RS17465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP6624_RS17475	COG1040	competence protein
CFBP6624_RS17480	COG2226	methyltransferase
CFBP6624_RS17495	COG0494	nUDIX hydrolase
CFBP6624_RS17505	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFBP6624_RS17510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFBP6624_RS17515	COG0653	protein targeting
CFBP6624_RS17765	COG2226	methyltransferase
CFBP6624_RS17770	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CFBP6624_RS17810	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP6624_RS17810	COG0489	protein tyrosine kinase activity
CFBP6624_RS17845	COG1216	Glycosyl transferase, family 2
CFBP6624_RS17855	COG0438	transferase activity, transferring glycosyl groups
CFBP6624_RS17865	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CFBP6624_RS17870	COG1088	dTDP-glucose 4,6-dehydratase activity
CFBP6624_RS17875	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFBP6624_RS17880	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFBP6624_RS17885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFBP6624_RS17890	COG2273	Hydrolase Family 16
CFBP6624_RS17890	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CFBP6624_RS17905	COG3842	ATPase activity
CFBP6624_RS17910	COG3833	ABC-type maltose transport systems, permease component
CFBP6624_RS17965	COG1396	sequence-specific DNA binding
CFBP6624_RS17975	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFBP6624_RS17980	COG1129	ABC transporter
CFBP6624_RS17985	COG4214	carbohydrate transport
CFBP6624_RS17990	COG4213	ABC transporter substrate-binding protein
CFBP6624_RS18005	COG0640	Transcriptional regulator
CFBP6624_RS18015	COG0346	lactoylglutathione lyase activity
CFBP6624_RS18020	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFBP6624_RS18020	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFBP6624_RS18025	COG4770	biotin carboxylase activity
CFBP6624_RS18035	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CFBP6624_RS18045	COG0625	glutathione transferase activity
CFBP6624_RS18050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP6624_RS18055	COG3800	Transcriptional regulator
CFBP6624_RS18055	COG1396	sequence-specific DNA binding
CFBP6624_RS18065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP6624_RS18075	COG0300	oxidoreductase activity
CFBP6624_RS18085	COG2096	Adenosyltransferase
CFBP6624_RS18095	COG2086	electron transfer activity
CFBP6624_RS18105	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP6624_RS18110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFBP6624_RS18115	COG0165	Argininosuccinate lyase
CFBP6624_RS18150	COG2884	Cell division ATP-binding protein ftsE
CFBP6624_RS18170	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CFBP6624_RS18185	COG0287	Prephenate dehydrogenase
CFBP6624_RS18190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP6624_RS18195	COG2226	methyltransferase
CFBP6624_RS18200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6624_RS18215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFBP6624_RS18220	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFBP6624_RS18255	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFBP6624_RS18260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFBP6624_RS18275	COG4974	Belongs to the 'phage' integrase family
CFBP6624_RS18280	COG0825	malonyl-CoA metabolic process
CFBP6624_RS18285	COG3034	peptidoglycan biosynthetic process
CFBP6624_RS18290	COG0425	Belongs to the sulfur carrier protein TusA family
CFBP6624_RS18290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFBP6624_RS18300	COG0523	cobalamin synthesis protein
CFBP6624_RS18305	COG1686	Belongs to the peptidase S11 family
CFBP6624_RS18310	COG1473	amidohydrolase
CFBP6624_RS18315	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CFBP6624_RS18325	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS18335	COG1879	ABC-type sugar transport system periplasmic component
CFBP6624_RS18340	COG1830	Aldolase
CFBP6624_RS18345	COG1802	Transcriptional regulator
CFBP6624_RS18350	COG1653	transport
CFBP6624_RS18360	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS18365	COG1063	alcohol dehydrogenase
CFBP6624_RS18375	COG3842	ATPase activity
CFBP6624_RS18380	COG2376	Dihydroxyacetone kinase
CFBP6624_RS18390	COG1902	pentaerythritol trinitrate reductase activity
CFBP6624_RS18435	COG0667	Aldo Keto reductase
CFBP6624_RS18440	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS18450	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS18460	COG3962	Belongs to the TPP enzyme family
CFBP6624_RS18465	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS18470	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS18485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP6624_RS18505	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS18510	COG1129	ABC transporter
CFBP6624_RS18520	COG4953	penicillin-binding protein 1C
CFBP6624_RS18525	COG2373	Large extracellular alpha-helical protein
CFBP6624_RS18530	COG2835	tetraacyldisaccharide 4'-kinase activity
CFBP6624_RS18540	COG3118	belongs to the thioredoxin family
CFBP6624_RS18560	COG0482	sulfurtransferase activity
CFBP6624_RS18575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP6624_RS18590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP6624_RS18595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP6624_RS18600	COG0037	tRNA processing
CFBP6624_RS18610	COG2885	chlorophyll binding
CFBP6624_RS18615	COG0823	Involved in the tonB-independent uptake of proteins
CFBP6624_RS18635	COG0824	Thioesterase
CFBP6624_RS18645	COG0494	nUDIX hydrolase
CFBP6624_RS18655	COG1408	metallophosphoesterase
CFBP6624_RS18660	COG2255	four-way junction helicase activity
CFBP6624_RS18665	COG0632	four-way junction helicase activity
CFBP6624_RS18670	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CFBP6624_RS18675	COG0840	transmembrane signaling receptor activity
CFBP6624_RS18680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS18685	COG0217	transcriptional regulatory protein
CFBP6624_RS18700	COG1692	metallophosphoesterase
CFBP6624_RS18710	COG1253	flavin adenine dinucleotide binding
CFBP6624_RS18755	COG0126	phosphoglycerate kinase activity
CFBP6624_RS18760	COG3588	fructose-bisphosphate aldolase
CFBP6624_RS18780	COG0254	rRNA binding
CFBP6624_RS18785	COG1132	(ABC) transporter
CFBP6624_RS18805	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6624_RS18835	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFBP6624_RS18840	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFBP6624_RS18845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFBP6624_RS18850	COG0457	Tetratricopeptide repeat
CFBP6624_RS18855	COG3750	Belongs to the UPF0335 family
CFBP6624_RS18875	COG0469	pyruvate kinase activity
CFBP6624_RS18880	COG3108	Peptidase M15
CFBP6624_RS18885	COG2204	response regulator
CFBP6624_RS18890	COG1164	Oligoendopeptidase f
CFBP6624_RS18895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP6624_RS18905	COG5310	Homospermidine synthase
CFBP6624_RS18915	COG0737	Belongs to the 5'-nucleotidase family
CFBP6624_RS18920	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CFBP6624_RS18925	COG0330	HflC and HflK could
CFBP6624_RS18955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP6624_RS18960	COG2951	lytic endotransglycosylase activity
CFBP6624_RS18975	COG2205	protein histidine kinase activity
CFBP6624_RS18985	COG0067	glutamate synthase
CFBP6624_RS18985	COG0069	glutamate synthase activity
CFBP6624_RS18985	COG0070	glutamate synthase
CFBP6624_RS19000	COG2205	protein histidine kinase activity
CFBP6624_RS19005	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CFBP6624_RS19010	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CFBP6624_RS19015	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CFBP6624_RS19025	COG0252	asparaginase activity
CFBP6624_RS19035	COG1027	Aspartate ammonia-lyase
CFBP6624_RS19040	COG2186	Transcriptional regulator
CFBP6624_RS19045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6624_RS19060	COG1309	transcriptional regulator
CFBP6624_RS19070	COG3842	ATPase activity
CFBP6624_RS19075	COG1177	transmembrane transport
CFBP6624_RS19095	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS19100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS19110	COG2267	carboxylic ester hydrolase activity
CFBP6624_RS19125	COG1126	abc transporter atp-binding protein
CFBP6624_RS19130	COG0765	amino acid transport
CFBP6624_RS19150	COG0174	glutamine synthetase
CFBP6624_RS19155	COG0069	glutamate synthase activity
CFBP6624_RS19160	COG2218	PFAM glutamate synthase alpha subunit domain protein
CFBP6624_RS19165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFBP6624_RS19175	COG4977	sequence-specific DNA binding
CFBP6624_RS19180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS19185	COG4311	Sarcosine oxidase, delta subunit
CFBP6624_RS19190	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP6624_RS19190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP6624_RS19200	COG1609	Transcriptional regulator
CFBP6624_RS19220	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6624_RS19225	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS19230	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6624_RS19235	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6624_RS19240	COG2957	Belongs to the agmatine deiminase family
CFBP6624_RS19255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6624_RS19265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS19270	COG0601	transmembrane transport
CFBP6624_RS19275	COG0747	negative chemotaxis
CFBP6624_RS19285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP6624_RS19290	COG1454	alcohol dehydrogenase
CFBP6624_RS19335	COG2307	Protein conserved in bacteria
CFBP6624_RS19335	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP6624_RS19350	COG0488	(ABC) transporter
CFBP6624_RS19355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6624_RS19360	COG1304	FMN binding
CFBP6624_RS19400	COG0765	amino acid transport
CFBP6624_RS19405	COG0765	amino acid transport
CFBP6624_RS19415	COG1063	alcohol dehydrogenase
CFBP6624_RS19420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP6624_RS19425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6624_RS19435	COG0765	amino acid transport
CFBP6624_RS19440	COG0765	amino acid transport
CFBP6624_RS19445	COG4221	oxidoreductase activity
CFBP6624_RS19450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6624_RS19455	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS19460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6624_RS19475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP6624_RS19490	COG0697	spore germination
CFBP6624_RS19495	COG0697	spore germination
CFBP6624_RS19500	COG0511	ligase activity, forming carbon-carbon bonds
CFBP6624_RS19505	COG0439	Biotin carboxylase
CFBP6624_RS19515	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP6624_RS19520	COG1984	allophanate hydrolase subunit 2
CFBP6624_RS19525	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP6624_RS19530	COG3842	ATPase activity
CFBP6624_RS19540	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP6624_RS19550	COG0436	Aminotransferase
CFBP6624_RS19565	COG1070	Carbohydrate kinase
CFBP6624_RS19570	COG1830	Aldolase
CFBP6624_RS19575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFBP6624_RS19580	COG0667	Aldo Keto reductase
CFBP6624_RS19590	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS19595	COG1129	ABC transporter
CFBP6624_RS19600	COG1879	ABC-type sugar transport system periplasmic component
CFBP6624_RS19630	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6624_RS19645	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP6624_RS19660	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS19675	COG3842	ATPase activity
CFBP6624_RS19690	COG1648	precorrin-2 dehydrogenase activity
CFBP6624_RS19690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP6624_RS19695	COG0243	molybdopterin cofactor binding
CFBP6624_RS19710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFBP6624_RS19715	COG1116	anion transmembrane transporter activity
CFBP6624_RS19720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6624_RS19725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6624_RS19735	COG3707	response regulator
CFBP6624_RS19740	COG1802	Transcriptional regulator
CFBP6624_RS19745	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP6624_RS19750	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP6624_RS19755	COG4336	lyase activity
CFBP6624_RS19760	COG1984	allophanate hydrolase subunit 2
CFBP6624_RS19765	COG4770	biotin carboxylase activity
CFBP6624_RS19770	COG0366	Alpha amylase catalytic
CFBP6624_RS19780	COG4771	TonB-dependent receptor
CFBP6624_RS19785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFBP6624_RS19805	COG1414	Transcriptional regulator
CFBP6624_RS19810	COG1475	DNA binding
CFBP6624_RS19815	COG1192	Involved in chromosome partitioning
CFBP6624_RS19845	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFBP6624_RS19855	COG2986	histidine ammonia-lyase
CFBP6624_RS19860	COG1228	amidohydrolase
CFBP6624_RS19865	COG0402	S-adenosylhomocysteine deaminase activity
CFBP6624_RS19915	COG0596	Alpha beta hydrolase
CFBP6624_RS19945	COG1454	alcohol dehydrogenase
CFBP6624_RS19980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP6624_RS20000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP6624_RS20025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6624_RS20030	COG4172	Belongs to the ABC transporter superfamily
CFBP6624_RS20035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS20040	COG0601	transmembrane transport
CFBP6624_RS20045	COG4166	transmembrane transport
CFBP6624_RS20050	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS20075	COG2205	protein histidine kinase activity
CFBP6624_RS20095	COG0346	lactoylglutathione lyase activity
CFBP6624_RS20110	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CFBP6624_RS20120	COG2814	Major facilitator Superfamily
CFBP6624_RS20130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6624_RS20135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6624_RS20170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFBP6624_RS20175	COG0356	it plays a direct role in the translocation of protons across the membrane
CFBP6624_RS20185	COG0387	Pfam Sodium calcium exchanger
CFBP6624_RS20190	COG2268	Band 7 protein
CFBP6624_RS20200	COG1842	Phage shock protein A
CFBP6624_RS20210	COG0583	DNA-binding transcription factor activity
CFBP6624_RS20215	COG0477	Major facilitator Superfamily
CFBP6624_RS20255	COG2205	protein histidine kinase activity
CFBP6624_RS20260	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS20265	COG0671	phosphoesterase, PA-phosphatase related
CFBP6624_RS20285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CFBP6624_RS20295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CFBP6624_RS20300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6624_RS20305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFBP6624_RS20320	COG0010	Belongs to the arginase family
CFBP6624_RS20330	COG0697	spore germination
CFBP6624_RS20335	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS20360	COG0477	Major facilitator Superfamily
CFBP6624_RS20375	COG2194	sulfuric ester hydrolase activity
CFBP6624_RS20395	COG1120	ATPase activity
CFBP6624_RS20405	COG3474	cytochrome
CFBP6624_RS20410	COG2137	regulation of response to DNA damage stimulus
CFBP6624_RS20415	COG3386	PFAM SMP-30 Gluconolaconase
CFBP6624_RS20425	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS20430	COG1129	ABC transporter
CFBP6624_RS20435	COG1879	ABC-type sugar transport system periplasmic component
CFBP6624_RS20445	COG4585	Histidine kinase
CFBP6624_RS20450	COG2197	response regulator
CFBP6624_RS20460	COG2133	pyrroloquinoline quinone binding
CFBP6624_RS20470	COG0500	methyltransferase
CFBP6624_RS20475	COG0564	pseudouridine synthase activity
CFBP6624_RS20490	COG0517	IMP dehydrogenase activity
CFBP6624_RS20490	COG4175	Glycine betaine
CFBP6624_RS20495	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP6624_RS20505	COG4191	Histidine kinase
CFBP6624_RS20505	COG0784	Response regulator, receiver
CFBP6624_RS20515	COG0489	protein tyrosine kinase activity
CFBP6624_RS20515	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP6624_RS20520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP6624_RS20525	COG1215	transferase activity, transferring glycosyl groups
CFBP6624_RS20530	COG1215	transferase activity, transferring glycosyl groups
CFBP6624_RS20535	COG1215	transferase activity, transferring glycosyl groups
CFBP6624_RS20540	COG0438	transferase activity, transferring glycosyl groups
CFBP6624_RS20545	COG2273	Hydrolase Family 16
CFBP6624_RS20550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP6624_RS20555	COG2244	polysaccharide biosynthetic process
CFBP6624_RS20560	COG0463	Glycosyl transferase, family 2
CFBP6624_RS20565	COG2327	Polysaccharide pyruvyl transferase
CFBP6624_RS20570	COG1215	transferase activity, transferring glycosyl groups
CFBP6624_RS20590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP6624_RS20595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS20610	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP6624_RS20610	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP6624_RS20630	COG1523	belongs to the glycosyl hydrolase 13 family
CFBP6624_RS20635	COG0033	Phosphoglucomutase
CFBP6624_RS20640	COG0297	glycogen (starch) synthase activity
CFBP6624_RS20645	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CFBP6624_RS20650	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFBP6624_RS20655	COG0058	SHG alpha-glucan phosphorylase activity
CFBP6624_RS20670	COG1794	racemase activity, acting on amino acids and derivatives
CFBP6624_RS20675	COG1522	sequence-specific DNA binding
CFBP6624_RS20685	COG2084	Dehydrogenase
CFBP6624_RS20690	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS20695	COG1063	alcohol dehydrogenase
CFBP6624_RS20705	COG4988	ABC transporter
CFBP6624_RS20710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CFBP6624_RS20720	COG1294	oxidase, subunit
CFBP6624_RS20750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CFBP6624_RS20755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFBP6624_RS20790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6624_RS20820	COG0328	RNA-DNA hybrid ribonuclease activity
CFBP6624_RS20850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CFBP6624_RS20855	COG0539	negative regulation of cytoplasmic translation
CFBP6624_RS20885	COG4221	oxidoreductase activity
CFBP6624_RS20895	COG0006	proline dipeptidase activity
CFBP6624_RS20900	COG0747	negative chemotaxis
CFBP6624_RS20905	COG0601	transmembrane transport
CFBP6624_RS20910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS20915	COG0444	Belongs to the ABC transporter superfamily
CFBP6624_RS20920	COG4608	Belongs to the ABC transporter superfamily
CFBP6624_RS20925	COG0246	Mannitol dehydrogenase
CFBP6624_RS20940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS20965	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS20985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP6624_RS20990	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS21000	COG4993	Dehydrogenase
CFBP6624_RS21005	COG3685	Protein conserved in bacteria
CFBP6624_RS21010	COG1285	pathogenesis
CFBP6624_RS21035	COG0693	protein deglycase activity
CFBP6624_RS21060	COG0189	ligase activity
CFBP6624_RS21065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6624_RS21070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFBP6624_RS21080	COG0435	Glutathione S-transferase
CFBP6624_RS21085	COG0583	DNA-binding transcription factor activity
CFBP6624_RS21090	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS21100	COG1522	sequence-specific DNA binding
CFBP6624_RS21115	COG0784	Response regulator, receiver
CFBP6624_RS21135	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFBP6624_RS21150	COG0019	diaminopimelate decarboxylase activity
CFBP6624_RS21160	COG1309	transcriptional regulator
CFBP6624_RS21180	COG0527	aspartate kinase activity
CFBP6624_RS21190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFBP6624_RS21195	COG2890	protein-(glutamine-N5) methyltransferase activity
CFBP6624_RS21205	COG0542	response to heat
CFBP6624_RS21210	COG1196	nuclear chromosome segregation
CFBP6624_RS21210	COG0741	lytic transglycosylase activity
CFBP6624_RS21210	COG0739	heme binding
CFBP6624_RS21260	COG1129	ABC transporter
CFBP6624_RS21265	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS21270	COG1879	ABC-type sugar transport system periplasmic component
CFBP6624_RS21275	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6624_RS21280	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS21285	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6624_RS21290	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS21310	COG1126	abc transporter atp-binding protein
CFBP6624_RS21315	COG0765	amino acid transport
CFBP6624_RS21320	COG0765	amino acid transport
CFBP6624_RS21325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6624_RS21335	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS21340	COG3938	Belongs to the proline racemase family
CFBP6624_RS21345	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS21350	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS21450	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP6624_RS21455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6624_RS21470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CFBP6624_RS21485	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFBP6624_RS21495	COG2986	histidine ammonia-lyase
CFBP6624_RS21515	COG0584	glycerophosphoryl diester phosphodiesterase
CFBP6624_RS21520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS21530	COG4608	Belongs to the ABC transporter superfamily
CFBP6624_RS21535	COG0444	Belongs to the ABC transporter superfamily
CFBP6624_RS21555	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS21560	COG5002	protein histidine kinase activity
CFBP6624_RS21565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6624_RS21570	COG1136	(ABC) transporter
CFBP6624_RS21570	COG0577	efflux transmembrane transporter activity
CFBP6624_RS21580	COG1733	regulation of RNA biosynthetic process
CFBP6624_RS21585	COG0583	DNA-binding transcription factor activity
CFBP6624_RS21590	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS21615	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS21620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFBP6624_RS21630	COG3842	ATPase activity
CFBP6624_RS21635	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS21640	COG1175	transmembrane transport
CFBP6624_RS21650	COG1053	succinate dehydrogenase
CFBP6624_RS21650	COG3976	FMN-binding domain protein
CFBP6624_RS21655	COG1609	Transcriptional regulator
CFBP6624_RS21660	COG1522	sequence-specific DNA binding
CFBP6624_RS21670	COG1116	anion transmembrane transporter activity
CFBP6624_RS21675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6624_RS21680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6624_RS21690	COG0405	Gamma-glutamyltransferase
CFBP6624_RS21735	COG1846	Transcriptional regulator
CFBP6624_RS21740	COG4178	(ABC) transporter
CFBP6624_RS21765	COG1929	Belongs to the glycerate kinase type-1 family
CFBP6624_RS21800	COG0583	DNA-binding transcription factor activity
CFBP6624_RS21805	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6624_RS21815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6624_RS21825	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS21835	COG1653	transport
CFBP6624_RS21840	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS21845	COG4209	transmembrane transport
CFBP6624_RS21850	COG3842	ATPase activity
CFBP6624_RS21855	COG1802	Transcriptional regulator
CFBP6624_RS21865	COG1309	transcriptional regulator
CFBP6624_RS21880	COG1136	(ABC) transporter
CFBP6624_RS21895	COG1063	alcohol dehydrogenase
CFBP6624_RS21905	COG1879	ABC-type sugar transport system periplasmic component
CFBP6624_RS21915	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS22035	COG5001	Diguanylate cyclase
CFBP6624_RS22035	COG3300	MHYT domain
CFBP6624_RS22060	COG1609	Transcriptional regulator
CFBP6624_RS22065	COG1178	ABC-type Fe3 transport system permease component
CFBP6624_RS22070	COG3842	ATPase activity
CFBP6624_RS22090	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6624_RS22100	COG1253	flavin adenine dinucleotide binding
CFBP6624_RS22120	COG3842	ATPase activity
CFBP6624_RS22125	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS22130	COG1175	transmembrane transport
CFBP6624_RS22135	COG1653	transport
CFBP6624_RS22145	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS22150	COG1609	Transcriptional regulator
CFBP6624_RS22165	COG0583	DNA-binding transcription factor activity
CFBP6624_RS22180	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS22185	COG1609	Transcriptional regulator
CFBP6624_RS22190	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6624_RS22205	COG3842	ATPase activity
CFBP6624_RS22210	COG1177	transmembrane transport
CFBP6624_RS22240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS22250	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP6624_RS22250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP6624_RS22265	COG0668	transmembrane transport
CFBP6624_RS22285	COG1879	ABC-type sugar transport system periplasmic component
CFBP6624_RS22290	COG1129	ABC transporter
CFBP6624_RS22295	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS22300	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS22305	COG1609	Transcriptional regulator
CFBP6624_RS22315	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS22375	COG0714	Associated with various cellular activities
CFBP6624_RS22380	COG3256	nitric oxide reductase
CFBP6624_RS22395	COG1845	cytochrome c oxidase, subunit III
CFBP6624_RS22415	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CFBP6624_RS22420	COG3189	MarR family transcriptional regulator
CFBP6624_RS22430	COG0826	peptidase U32
CFBP6624_RS22465	COG4459	periplasmic nitrate reductase
CFBP6624_RS22480	COG0243	molybdopterin cofactor binding
CFBP6624_RS22490	COG3005	denitrification pathway
CFBP6624_RS22505	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6624_RS22510	COG1535	isochorismatase
CFBP6624_RS22510	COG3433	isochorismatase activity
CFBP6624_RS22515	COG1021	2,3-dihydroxybenzoate-AMP ligase
CFBP6624_RS22520	COG1169	isochorismate synthase
CFBP6624_RS22530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFBP6624_RS22530	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CFBP6624_RS22535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFBP6624_RS22545	COG2375	cellular response to nickel ion
CFBP6624_RS22555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6624_RS22560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6624_RS22565	COG1120	ATPase activity
CFBP6624_RS22570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6624_RS22580	COG4774	siderophore transport
CFBP6624_RS22580	COG1629	transport
CFBP6624_RS22585	COG1960	acyl-CoA dehydrogenase activity
CFBP6624_RS22590	COG0583	DNA-binding transcription factor activity
CFBP6624_RS22595	COG1609	Transcriptional regulator
CFBP6624_RS22605	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP6624_RS22615	COG3842	ATPase activity
CFBP6624_RS22625	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP6624_RS22630	COG0583	DNA-binding transcription factor activity
CFBP6624_RS22635	COG2814	Major facilitator Superfamily
CFBP6624_RS22640	COG1473	amidohydrolase
CFBP6624_RS22655	COG0747	negative chemotaxis
CFBP6624_RS22660	COG0601	transmembrane transport
CFBP6624_RS22665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS22670	COG0444	Belongs to the ABC transporter superfamily
CFBP6624_RS22675	COG4608	Belongs to the ABC transporter superfamily
CFBP6624_RS22680	COG0583	DNA-binding transcription factor activity
CFBP6624_RS22685	COG0747	negative chemotaxis
CFBP6624_RS22695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS22700	COG0154	amidase activity
CFBP6624_RS22705	COG0693	protein deglycase activity
CFBP6624_RS22715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS22720	COG0601	transmembrane transport
CFBP6624_RS22725	COG4166	transmembrane transport
CFBP6624_RS22730	COG1473	amidohydrolase
CFBP6624_RS22735	COG4172	Belongs to the ABC transporter superfamily
CFBP6624_RS22740	COG2390	Transcriptional regulator
CFBP6624_RS22750	COG1175	transmembrane transport
CFBP6624_RS22755	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS22775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP6624_RS22805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP6624_RS22810	COG0850	regulation of cytokinetic process
CFBP6624_RS22815	COG2894	cell division
CFBP6624_RS22820	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CFBP6624_RS22830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6624_RS22835	COG5001	Diguanylate cyclase
CFBP6624_RS22855	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS22865	COG1653	transport
CFBP6624_RS22870	COG1175	transmembrane transport
CFBP6624_RS22875	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS22880	COG3842	ATPase activity
CFBP6624_RS22890	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS22895	COG1054	Belongs to the UPF0176 family
CFBP6624_RS22905	COG2954	triphosphatase activity
CFBP6624_RS22910	COG0800	Aldolase
CFBP6624_RS22935	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CFBP6624_RS22975	COG0523	cobalamin synthesis protein
CFBP6624_RS22985	COG1846	Transcriptional regulator
CFBP6624_RS22990	COG1609	Transcriptional regulator
CFBP6624_RS23000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6624_RS23015	COG3718	enzyme involved in inositol metabolism
CFBP6624_RS23025	COG3962	Belongs to the TPP enzyme family
CFBP6624_RS23030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6624_RS23060	COG0683	leucine binding
CFBP6624_RS23070	COG2207	Transcriptional regulator
CFBP6624_RS23080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS23090	COG0747	negative chemotaxis
CFBP6624_RS23095	COG4172	Belongs to the ABC transporter superfamily
CFBP6624_RS23110	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CFBP6624_RS23110	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6624_RS23120	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP6624_RS23125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP6624_RS23130	COG1126	abc transporter atp-binding protein
CFBP6624_RS23135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6624_RS23140	COG0765	amino acid transport
CFBP6624_RS23145	COG0765	amino acid transport
CFBP6624_RS23155	COG3485	protocatechuate 3,4-dioxygenase
CFBP6624_RS23160	COG3485	protocatechuate 3,4-dioxygenase
CFBP6624_RS23165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFBP6624_RS23175	COG0583	DNA-binding transcription factor activity
CFBP6624_RS23190	COG1414	Transcriptional regulator
CFBP6624_RS23200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFBP6624_RS23205	COG0183	Belongs to the thiolase family
CFBP6624_RS23210	COG1609	Transcriptional regulator
CFBP6624_RS23225	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6624_RS23230	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS23240	COG1609	Transcriptional regulator
CFBP6624_RS23245	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS23250	COG1175	transmembrane transport
CFBP6624_RS23255	COG3842	ATPase activity
CFBP6624_RS23265	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFBP6624_RS23295	COG3842	ATPase activity
CFBP6624_RS23300	COG4149	molybdate abc transporter
CFBP6624_RS23310	COG0584	glycerophosphoryl diester phosphodiesterase
CFBP6624_RS23315	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6624_RS23325	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFBP6624_RS23345	COG0385	Bile acid
CFBP6624_RS23350	COG0667	Aldo Keto reductase
CFBP6624_RS23355	COG0583	DNA-binding transcription factor activity
CFBP6624_RS23365	COG1132	(ABC) transporter
CFBP6624_RS23385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP6624_RS23390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP6624_RS23405	COG0463	Glycosyl transferase, family 2
CFBP6624_RS23425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFBP6624_RS23435	COG4106	trans-aconitate 2-methyltransferase activity
CFBP6624_RS23440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP6624_RS23445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFBP6624_RS23455	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFBP6624_RS23460	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFBP6624_RS23465	COG1088	dTDP-glucose 4,6-dehydratase activity
CFBP6624_RS23470	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CFBP6624_RS23495	COG0444	Belongs to the ABC transporter superfamily
CFBP6624_RS23500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS23505	COG0601	transmembrane transport
CFBP6624_RS23510	COG2186	Transcriptional regulator
CFBP6624_RS23515	COG1312	Catalyzes the dehydration of D-mannonate
CFBP6624_RS23530	COG5001	Diguanylate cyclase
CFBP6624_RS23530	COG3300	MHYT domain
CFBP6624_RS23545	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP6624_RS23555	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP6624_RS23560	COG0306	phosphate transporter
CFBP6624_RS23565	COG1392	Phosphate transport regulator
CFBP6624_RS23590	COG5002	protein histidine kinase activity
CFBP6624_RS23640	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CFBP6624_RS23655	COG4774	siderophore transport
CFBP6624_RS23665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6624_RS23670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6624_RS23675	COG1120	ATPase activity
CFBP6624_RS23680	COG0583	DNA-binding transcription factor activity
CFBP6624_RS23720	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS23725	COG0583	DNA-binding transcription factor activity
CFBP6624_RS23735	COG3119	arylsulfatase activity
CFBP6624_RS23740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6624_RS23745	COG3842	ATPase activity
CFBP6624_RS23750	COG0165	Argininosuccinate lyase
CFBP6624_RS23755	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS23760	COG1175	transmembrane transport
CFBP6624_RS23765	COG2182	Extracellular solute-binding protein
CFBP6624_RS23770	COG1940	carbohydrate kinase activity
CFBP6624_RS23795	COG1486	melibiose metabolic process
CFBP6624_RS23800	COG0747	negative chemotaxis
CFBP6624_RS23805	COG0601	transmembrane transport
CFBP6624_RS23810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS23815	COG4172	Belongs to the ABC transporter superfamily
CFBP6624_RS23820	COG1486	melibiose metabolic process
CFBP6624_RS23825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6624_RS23830	COG1129	ABC transporter
CFBP6624_RS23830	COG0842	Transport permease protein
CFBP6624_RS23835	COG0842	Transport permease protein
CFBP6624_RS23850	COG0784	Response regulator, receiver
CFBP6624_RS23855	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP6624_RS23865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6624_RS23870	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP6624_RS23885	COG0765	amino acid transport
CFBP6624_RS23895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6624_RS23905	COG3938	Belongs to the proline racemase family
CFBP6624_RS23920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6624_RS23925	COG0765	amino acid transport
CFBP6624_RS23930	COG0765	amino acid transport
CFBP6624_RS23940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6624_RS23955	COG0402	S-adenosylhomocysteine deaminase activity
CFBP6624_RS23965	COG0601	transmembrane transport
CFBP6624_RS23970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS23980	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP6624_RS23985	COG0444	Belongs to the ABC transporter superfamily
CFBP6624_RS23990	COG4608	Belongs to the ABC transporter superfamily
CFBP6624_RS23995	COG1802	Transcriptional regulator
CFBP6624_RS24000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP6624_RS24020	COG3237	CsbD-like
CFBP6624_RS24025	COG2197	response regulator
CFBP6624_RS24045	COG3383	formate dehydrogenase (NAD+) activity
CFBP6624_RS24055	COG2223	nitrite transmembrane transporter activity
CFBP6624_RS24065	COG1278	Cold shock
CFBP6624_RS24070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6624_RS24085	COG0747	negative chemotaxis
CFBP6624_RS24090	COG0601	transmembrane transport
CFBP6624_RS24095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS24100	COG4172	Belongs to the ABC transporter superfamily
CFBP6624_RS24105	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6624_RS24115	COG2186	Transcriptional regulator
CFBP6624_RS24120	COG0747	negative chemotaxis
CFBP6624_RS24125	COG0601	transmembrane transport
CFBP6624_RS24130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6624_RS24135	COG0405	Gamma-glutamyltransferase
CFBP6624_RS24160	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6624_RS24165	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6624_RS24175	COG3842	ATPase activity
CFBP6624_RS24190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP6624_RS24195	COG3181	Tripartite tricarboxylate transporter family receptor
CFBP6624_RS24200	COG5265	(ABC) transporter
CFBP6624_RS24205	COG0488	(ABC) transporter
CFBP6624_RS24225	COG1129	ABC transporter
CFBP6624_RS24230	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS24250	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6624_RS24270	COG4221	oxidoreductase activity
CFBP6624_RS24275	COG0583	DNA-binding transcription factor activity
CFBP6624_RS24280	COG1126	abc transporter atp-binding protein
CFBP6624_RS24285	COG0765	amino acid transport
CFBP6624_RS24290	COG0765	amino acid transport
CFBP6624_RS24295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6624_RS24300	COG3608	succinylglutamate desuccinylase aspartoacylase
CFBP6624_RS24305	COG0006	proline dipeptidase activity
CFBP6624_RS24310	COG2423	ornithine cyclodeaminase activity
CFBP6624_RS24315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFBP6624_RS24320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6624_RS24325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6624_RS24330	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS24335	COG1522	sequence-specific DNA binding
CFBP6624_RS24395	COG0110	maltose O-acetyltransferase activity
CFBP6624_RS24440	COG1192	Involved in chromosome partitioning
CFBP6624_RS24445	COG1475	DNA binding
CFBP6624_RS24450	COG0640	Transcriptional regulator
CFBP6624_RS24465	COG4644	lycopene metabolic process
CFBP6624_RS24495	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFBP6624_RS24505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP6624_RS24510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFBP6624_RS24515	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6624_RS24525	COG0789	Transcriptional regulator
CFBP6624_RS24530	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP6624_RS24540	COG2217	Heavy metal translocating P-type atpase
CFBP6624_RS24550	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6624_RS24555	COG2194	sulfuric ester hydrolase activity
CFBP6624_RS24560	COG3034	peptidoglycan biosynthetic process
CFBP6624_RS24570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFBP6624_RS24575	COG1230	cation diffusion facilitator family transporter
CFBP6624_RS24580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP6624_RS24615	COG1999	signal sequence binding
CFBP6624_RS24625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFBP6624_RS24635	COG2132	Multicopper oxidase
CFBP6624_RS24645	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6624_RS24695	COG2124	cytochrome p450
CFBP6624_RS24700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6624_RS24700	COG3453	Protein conserved in bacteria
CFBP6624_RS24710	COG1522	sequence-specific DNA binding
CFBP6624_RS24720	COG4644	lycopene metabolic process
CFBP6624_RS24750	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFBP6624_RS24770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFBP6624_RS24805	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS24815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP6624_RS24820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP6624_RS24830	COG3609	addiction module antidote protein, CC2985 family
CFBP6624_RS24865	COG0455	bacterial-type flagellum organization
CFBP6624_RS24880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6624_RS24900	COG4644	lycopene metabolic process
CFBP6624_RS24930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFBP6624_RS24950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFBP6624_RS25015	COG2132	Multicopper oxidase
CFBP6624_RS25035	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CFBP6624_RS25040	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CFBP6624_RS25055	COG2217	Heavy metal translocating P-type atpase
CFBP6624_RS25075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP6624_RS25090	COG0583	DNA-binding transcription factor activity
CFBP6624_RS25110	COG0789	Transcriptional regulator
CFBP6624_RS25125	COG1937	Protein conserved in bacteria
CFBP6624_RS25140	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6624_RS25200	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CFBP6624_RS25205	COG4372	Transposase
CFBP6624_RS25210	COG3436	PFAM IS66 Orf2 family protein
CFBP6624_RS25215	COG2963	transposase activity
CFBP6624_RS25235	COG0210	DNA helicase
CFBP6624_RS25250	COG1074	ATP-dependent DNA helicase activity
CFBP6624_RS25380	COG1192	Involved in chromosome partitioning
CFBP6624_RS25385	COG1475	DNA binding
CFBP6624_RS25390	COG1414	Transcriptional regulator
CFBP6624_RS25420	COG3838	Conjugal transfer protein Trbc
CFBP6624_RS25425	COG3702	type iv secretory pathway
CFBP6624_RS25430	COG3451	type IV secretory pathway VirB4
CFBP6624_RS25445	COG3704	protein secretion by the type IV secretion system
CFBP6624_RS25455	COG3736	Type IV secretory pathway, component VirB8
CFBP6624_RS25460	COG3504	Conjugal transfer protein
CFBP6624_RS25465	COG2948	multi-organism process
CFBP6624_RS25470	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CFBP6624_RS25560	COG3609	addiction module antidote protein, CC2985 family
CFBP6624_RS25600	COG3505	Type IV secretory pathway VirD4
CFBP6624_RS25640	COG2197	response regulator
CFBP6624_RS25660	COG2086	electron transfer activity
CFBP6624_RS25665	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6624_RS25675	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP6624_RS25700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP6624_RS25705	COG0318	PFAM AMP-dependent synthetase and ligase
CFBP6624_RS25710	COG1309	transcriptional regulator
CFBP6624_RS25715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP6624_RS25730	COG4644	lycopene metabolic process
CFBP6624_RS25735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6624_RS25740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6624_RS25745	COG1454	alcohol dehydrogenase
CFBP6624_RS25755	COG1414	Transcriptional regulator
CFBP6624_RS25780	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CFBP6624_RS25800	COG1309	transcriptional regulator
CFBP6624_RS25805	COG3920	Histidine kinase
CFBP6624_RS25815	COG1309	transcriptional regulator
CFBP6624_RS25855	COG0693	protein deglycase activity
CFBP6624_RS25875	COG4221	oxidoreductase activity
CFBP6624_RS25880	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CFBP6624_RS25900	COG0583	DNA-binding transcription factor activity
CFBP6624_RS25950	COG1609	Transcriptional regulator
CFBP6624_RS25960	COG0673	inositol 2-dehydrogenase activity
CFBP6624_RS25965	COG0363	glucosamine-6-phosphate deaminase activity
CFBP6624_RS25970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFBP6624_RS25975	COG3842	ATPase activity
CFBP6624_RS25985	COG1175	transmembrane transport
CFBP6624_RS25990	COG0395	ABC-type sugar transport system, permease component
CFBP6624_RS25995	COG1312	Catalyzes the dehydration of D-mannonate
CFBP6624_RS26000	COG0246	Mannitol dehydrogenase
CFBP6624_RS26030	COG5001	Diguanylate cyclase
CFBP6624_RS26030	COG3300	MHYT domain
CFBP6624_RS26045	COG2084	Dehydrogenase
CFBP6624_RS26060	COG0765	amino acid transport
CFBP6624_RS26065	COG0765	amino acid transport
CFBP6624_RS26070	COG3481	metal-dependent phosphohydrolase, HD sub domain
CFBP6624_RS26135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6624_RS26140	COG4644	lycopene metabolic process
CFBP6624_RS26150	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6624_RS26175	COG2814	Major facilitator Superfamily
CFBP6624_RS26200	COG0789	Transcriptional regulator
CFBP6624_RS26270	COG0586	Pfam SNARE associated Golgi protein
CFBP6624_RS26280	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS26365	COG0671	phosphoesterase, PA-phosphatase related
CFBP6624_RS26370	COG2132	Multicopper oxidase
CFBP6624_RS26385	COG2194	sulfuric ester hydrolase activity
CFBP6624_RS26450	COG0038	chloride channel
CFBP6624_RS26455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFBP6624_RS26470	COG0148	phosphopyruvate hydratase activity
CFBP6624_RS26480	COG0640	Transcriptional regulator
CFBP6624_RS26485	COG0431	NADPH-dependent FMN reductase
CFBP6624_RS26495	COG2072	flavoprotein involved in K transport
CFBP6624_RS26500	COG0798	PFAM Bile acid sodium symporter
CFBP6624_RS26510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFBP6624_RS26525	COG3639	organic phosphonate transmembrane transporter activity
CFBP6624_RS26530	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFBP6624_RS26545	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS26550	COG0704	Plays a role in the regulation of phosphate uptake
CFBP6624_RS26560	COG0581	inorganic phosphate transmembrane transporter activity
CFBP6624_RS26565	COG0573	inorganic phosphate transmembrane transporter activity
CFBP6624_RS26570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFBP6624_RS26575	COG0745	RESPONSE REGULATOR receiver
CFBP6624_RS26585	COG3852	Histidine kinase
CFBP6624_RS26590	COG2204	response regulator
CFBP6624_RS26635	COG0464	growth
CFBP6624_RS26690	COG3453	Protein conserved in bacteria
CFBP6624_RS26690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6624_RS26710	COG0730	response to heat
CFBP6624_RS26720	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6624_RS26730	COG2132	Multicopper oxidase
CFBP6624_RS26785	COG3034	peptidoglycan biosynthetic process
CFBP6624_RS26795	COG1968	undecaprenyl-diphosphatase activity
CFBP6624_RS26800	COG0785	Cytochrome C biogenesis protein
CFBP6624_RS26805	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFBP6624_RS26820	COG2124	cytochrome p450
CFBP6624_RS26825	COG0789	Transcriptional regulator
CFBP6624_RS26835	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFBP6624_RS26855	COG1959	2 iron, 2 sulfur cluster binding
CFBP6624_RS26865	COG1396	sequence-specific DNA binding
CFBP6624_RS26870	COG3550	peptidyl-serine autophosphorylation