locus-tag	class	description
CFBP6625_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFBP6625_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP6625_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFBP6625_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFBP6625_RS00025	COG1420	regulation of RNA biosynthetic process
CFBP6625_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFBP6625_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP6625_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFBP6625_RS00050	COG1137	ATPase activity
CFBP6625_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CFBP6625_RS00065	COG0616	signal peptide processing
CFBP6625_RS00070	COG0776	regulation of translation
CFBP6625_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP6625_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFBP6625_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFBP6625_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFBP6625_RS00115	COG0728	peptidoglycan biosynthetic process
CFBP6625_RS00125	COG0180	Tryptophanyl-tRNA synthetase
CFBP6625_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CFBP6625_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP6625_RS00165	COG1702	phosphate starvation-inducible protein PhoH
CFBP6625_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFBP6625_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CFBP6625_RS00185	COG1396	sequence-specific DNA binding
CFBP6625_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFBP6625_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFBP6625_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6625_RS00210	COG0242	peptide deformylase activity
CFBP6625_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFBP6625_RS00220	COG0101	tRNA pseudouridine synthase activity
CFBP6625_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP6625_RS00235	COG2171	N-acyltransferase activity
CFBP6625_RS00245	COG2972	Histidine kinase
CFBP6625_RS00245	COG0840	transmembrane signaling receptor activity
CFBP6625_RS00255	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6625_RS00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFBP6625_RS00295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CFBP6625_RS00300	COG0706	membrane insertase activity
CFBP6625_RS00305	COG0594	ribonuclease P activity
CFBP6625_RS00310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFBP6625_RS00315	COG0840	transmembrane signaling receptor activity
CFBP6625_RS00335	COG2226	methyltransferase
CFBP6625_RS00340	COG3842	ATPase activity
CFBP6625_RS00350	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS00365	COG0427	acetyl-CoA hydrolase
CFBP6625_RS00375	COG3938	Belongs to the proline racemase family
CFBP6625_RS00380	COG0418	dihydroorotase activity
CFBP6625_RS00385	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFBP6625_RS00410	COG0166	Belongs to the GPI family
CFBP6625_RS00415	COG0318	PFAM AMP-dependent synthetase and ligase
CFBP6625_RS00420	COG3842	ATPase activity
CFBP6625_RS00425	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6625_RS00430	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP6625_RS00435	COG4774	siderophore transport
CFBP6625_RS00500	COG2326	polyphosphate kinase activity
CFBP6625_RS00505	COG5002	protein histidine kinase activity
CFBP6625_RS00510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFBP6625_RS00515	COG0573	inorganic phosphate transmembrane transporter activity
CFBP6625_RS00525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFBP6625_RS00530	COG0704	Plays a role in the regulation of phosphate uptake
CFBP6625_RS00535	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS00550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFBP6625_RS00555	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFBP6625_RS00565	COG2967	ApaG domain
CFBP6625_RS00575	COG0717	Belongs to the dCTP deaminase family
CFBP6625_RS00590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFBP6625_RS00640	COG0167	dihydroorotate dehydrogenase activity
CFBP6625_RS00655	COG2264	protein methyltransferase activity
CFBP6625_RS00675	COG1959	2 iron, 2 sulfur cluster binding
CFBP6625_RS00680	COG1201	RNA secondary structure unwinding
CFBP6625_RS00715	COG1960	acyl-CoA dehydrogenase activity
CFBP6625_RS00720	COG0183	Belongs to the thiolase family
CFBP6625_RS00730	COG1024	Enoyl-CoA hydratase
CFBP6625_RS00730	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP6625_RS00755	COG1320	monovalent cation:proton antiporter activity
CFBP6625_RS00760	COG2212	antiporter activity
CFBP6625_RS00765	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP6625_RS00770	COG0651	ATP synthesis coupled electron transport
CFBP6625_RS00775	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP6625_RS00780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFBP6625_RS00780	COG2111	Na H antiporter
CFBP6625_RS00790	COG0840	transmembrane signaling receptor activity
CFBP6625_RS00800	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS00805	COG2198	Histidine kinase
CFBP6625_RS00805	COG0643	Histidine kinase
CFBP6625_RS00810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CFBP6625_RS00815	COG2201	protein-glutamate methylesterase activity
CFBP6625_RS00820	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS00825	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CFBP6625_RS00835	COG1766	The M ring may be actively involved in energy transduction
CFBP6625_RS00840	COG2771	luxR family
CFBP6625_RS00850	COG0840	transmembrane signaling receptor activity
CFBP6625_RS00860	COG2205	protein histidine kinase activity
CFBP6625_RS00860	COG2198	Histidine kinase
CFBP6625_RS00860	COG0784	Response regulator, receiver
CFBP6625_RS00865	COG1970	mechanosensitive ion channel activity
CFBP6625_RS00870	COG0436	Aminotransferase
CFBP6625_RS00885	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CFBP6625_RS00890	COG0424	maF-like protein
CFBP6625_RS00895	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFBP6625_RS00905	COG5328	Belongs to the UPF0262 family
CFBP6625_RS00910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFBP6625_RS00920	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFBP6625_RS01085	COG1338	Plays a role in the flagellum-specific transport system
CFBP6625_RS01095	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CFBP6625_RS01105	COG1706	bacterial-type flagellum-dependent cell motility
CFBP6625_RS01110	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CFBP6625_RS01115	COG4786	Flagellar basal body rod
CFBP6625_RS01120	COG1677	Flagellar hook-basal body complex protein FliE
CFBP6625_RS01125	COG1558	bacterial-type flagellum-dependent cell motility
CFBP6625_RS01130	COG1815	bacterial-type flagellum-dependent cell motility
CFBP6625_RS01140	COG1157	protein secretion by the type III secretion system
CFBP6625_RS01145	COG4786	Flagellar basal body rod
CFBP6625_RS01155	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CFBP6625_RS01160	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP6625_RS01165	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP6625_RS01170	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP6625_RS01175	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP6625_RS01200	COG1360	Flagellar Motor Protein
CFBP6625_RS01225	COG1749	Flagellar hook protein flgE
CFBP6625_RS01245	COG5443	negative regulation of bacterial-type flagellum assembly
CFBP6625_RS01250	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CFBP6625_RS01260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP6625_RS01300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFBP6625_RS01305	COG1609	Transcriptional regulator
CFBP6625_RS01310	COG1653	transport
CFBP6625_RS01315	COG1175	transmembrane transport
CFBP6625_RS01320	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS01325	COG0366	Alpha amylase catalytic
CFBP6625_RS01330	COG3842	ATPase activity
CFBP6625_RS01345	COG0129	dihydroxy-acid dehydratase activity
CFBP6625_RS01350	COG0363	glucosamine-6-phosphate deaminase activity
CFBP6625_RS01355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFBP6625_RS01365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS01375	COG2081	HI0933 family
CFBP6625_RS01395	COG2224	Isocitrate lyase
CFBP6625_RS01410	COG3842	ATPase activity
CFBP6625_RS01415	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP6625_RS01420	COG1177	transmembrane transport
CFBP6625_RS01430	COG2205	protein histidine kinase activity
CFBP6625_RS01440	COG0248	Ppx GppA phosphatase
CFBP6625_RS01445	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CFBP6625_RS01450	COG0477	Major facilitator Superfamily
CFBP6625_RS01490	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFBP6625_RS01495	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFBP6625_RS01505	COG0142	geranyltranstransferase activity
CFBP6625_RS01540	COG0752	glycyl-tRNA synthetase alpha subunit
CFBP6625_RS01550	COG1704	LemA family
CFBP6625_RS01555	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFBP6625_RS01565	COG0751	glycine-tRNA ligase activity
CFBP6625_RS01575	COG1683	Conserved Protein
CFBP6625_RS01580	COG0840	transmembrane signaling receptor activity
CFBP6625_RS01590	COG0151	Belongs to the GarS family
CFBP6625_RS01595	COG2183	response to ionizing radiation
CFBP6625_RS01600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP6625_RS01630	COG0583	DNA-binding transcription factor activity
CFBP6625_RS01665	COG0306	phosphate transporter
CFBP6625_RS01675	COG0561	phosphatase activity
CFBP6625_RS01680	COG0438	transferase activity, transferring glycosyl groups
CFBP6625_RS01685	COG2186	Transcriptional regulator
CFBP6625_RS01695	COG0583	DNA-binding transcription factor activity
CFBP6625_RS01700	COG0277	FAD linked oxidase domain protein
CFBP6625_RS01710	COG0277	FAD linked oxidase domain protein
CFBP6625_RS01715	COG0247	lactate metabolic process
CFBP6625_RS01725	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6625_RS01730	COG2818	Glycosylase
CFBP6625_RS01740	COG2855	membrane
CFBP6625_RS01745	COG0583	DNA-binding transcription factor activity
CFBP6625_RS01775	COG0124	histidyl-tRNA synthetase
CFBP6625_RS01785	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFBP6625_RS01790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFBP6625_RS01795	COG2259	Doxx family
CFBP6625_RS01810	COG0459	protein refolding
CFBP6625_RS01815	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFBP6625_RS01825	COG0196	riboflavin kinase activity
CFBP6625_RS01830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFBP6625_RS01840	COG0590	tRNA wobble adenosine to inosine editing
CFBP6625_RS01845	COG1187	pseudouridine synthase activity
CFBP6625_RS01850	COG0742	ribosomal rna small subunit methyltransferase
CFBP6625_RS01855	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP6625_RS01860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP6625_RS01860	COG0475	glutathione-regulated potassium exporter activity
CFBP6625_RS01865	COG0312	modulator of DNA gyrase
CFBP6625_RS01880	COG1519	Transferase
CFBP6625_RS01890	COG1663	tetraacyldisaccharide 4'-kinase activity
CFBP6625_RS01905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFBP6625_RS01915	COG5001	Diguanylate cyclase
CFBP6625_RS01915	COG3300	MHYT domain
CFBP6625_RS01920	COG3386	PFAM SMP-30 Gluconolaconase
CFBP6625_RS01925	COG0800	Aldolase
CFBP6625_RS01930	COG3734	2-keto-3-deoxy-galactonokinase
CFBP6625_RS01935	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS01940	COG1414	Transcriptional regulator
CFBP6625_RS01945	COG2197	response regulator
CFBP6625_RS01950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6625_RS01965	COG3158	transport of potassium into the cell
CFBP6625_RS01980	COG0356	it plays a direct role in the translocation of protons across the membrane
CFBP6625_RS01990	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP6625_RS01995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP6625_RS02005	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFBP6625_RS02030	COG0009	L-threonylcarbamoyladenylate synthase
CFBP6625_RS02040	COG4638	Rieske (2fe-2S)
CFBP6625_RS02065	COG1960	acyl-CoA dehydrogenase activity
CFBP6625_RS02085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFBP6625_RS02095	COG0840	transmembrane signaling receptor activity
CFBP6625_RS02120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFBP6625_RS02125	COG1741	Belongs to the pirin family
CFBP6625_RS02130	COG1722	exodeoxyribonuclease VII activity
CFBP6625_RS02135	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFBP6625_RS02140	COG1268	BioY protein
CFBP6625_RS02145	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFBP6625_RS02150	COG1122	ATPase activity
CFBP6625_RS02155	COG3214	Protein conserved in bacteria
CFBP6625_RS02160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP6625_RS02160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP6625_RS02165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFBP6625_RS02180	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP6625_RS02185	COG0484	heat shock protein binding
CFBP6625_RS02195	COG0259	pyridoxamine-phosphate oxidase activity
CFBP6625_RS02215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP6625_RS02225	COG0312	modulator of DNA gyrase
CFBP6625_RS02240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP6625_RS02245	COG0109	protoheme IX farnesyltransferase activity
CFBP6625_RS02255	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CFBP6625_RS02270	COG3346	SURF1 family
CFBP6625_RS02275	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CFBP6625_RS02280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFBP6625_RS02285	COG0328	RNA-DNA hybrid ribonuclease activity
CFBP6625_RS02295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFBP6625_RS02295	COG0678	peroxiredoxin activity
CFBP6625_RS02305	COG1678	Uncharacterized ACR, COG1678
CFBP6625_RS02310	COG3237	CsbD-like
CFBP6625_RS02320	COG5001	Diguanylate cyclase
CFBP6625_RS02320	COG3300	MHYT domain
CFBP6625_RS02325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP6625_RS02330	COG0612	Peptidase, M16
CFBP6625_RS02350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP6625_RS02380	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CFBP6625_RS02390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6625_RS02420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFBP6625_RS02425	COG1196	nuclear chromosome segregation
CFBP6625_RS02435	COG2514	catechol 2,3-dioxygenase activity
CFBP6625_RS02440	COG0574	Belongs to the PEP-utilizing enzyme family
CFBP6625_RS02440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFBP6625_RS02450	COG1823	symporter activity
CFBP6625_RS02475	COG0579	oxidoreductase
CFBP6625_RS02495	COG2895	sulfate adenylyltransferase (ATP) activity
CFBP6625_RS02500	COG0175	sulfate reduction
CFBP6625_RS02505	COG0175	sulfate reduction
CFBP6625_RS02510	COG1959	2 iron, 2 sulfur cluster binding
CFBP6625_RS02515	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CFBP6625_RS02520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP6625_RS02525	COG4208	sulfate ABC transporter
CFBP6625_RS02530	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP6625_RS02550	COG2203	Gaf domain
CFBP6625_RS02550	COG2199	diguanylate cyclase activity
CFBP6625_RS02550	COG2200	EAL domain
CFBP6625_RS02565	COG1309	transcriptional regulator
CFBP6625_RS02570	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS02575	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CFBP6625_RS02625	COG0477	Major facilitator Superfamily
CFBP6625_RS02645	COG1793	dna ligase
CFBP6625_RS02660	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6625_RS02665	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6625_RS02670	COG1846	Transcriptional regulator
CFBP6625_RS02675	COG1764	response to oxidative stress
CFBP6625_RS02715	COG0488	(ABC) transporter
CFBP6625_RS02720	COG0433	COG0433 Predicted ATPase
CFBP6625_RS02730	COG1733	regulation of RNA biosynthetic process
CFBP6625_RS02735	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CFBP6625_RS02745	COG1280	lysine exporter protein (LysE YggA)
CFBP6625_RS02750	COG0656	L-ascorbic acid biosynthetic process
CFBP6625_RS02755	COG3781	membrane
CFBP6625_RS02760	COG2378	regulation of single-species biofilm formation
CFBP6625_RS02775	COG4106	trans-aconitate 2-methyltransferase activity
CFBP6625_RS02780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP6625_RS02785	COG0840	transmembrane signaling receptor activity
CFBP6625_RS02790	COG0583	DNA-binding transcription factor activity
CFBP6625_RS02805	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP6625_RS02825	COG3909	cytochrome
CFBP6625_RS02830	COG2010	Cytochrome c
CFBP6625_RS02855	COG0456	acetyltransferase
CFBP6625_RS02865	COG0789	Transcriptional regulator
CFBP6625_RS02895	COG4175	Glycine betaine
CFBP6625_RS02895	COG0517	IMP dehydrogenase activity
CFBP6625_RS02900	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP6625_RS02925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6625_RS02935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP6625_RS02935	COG2169	Transcriptional regulator
CFBP6625_RS02950	COG2514	catechol 2,3-dioxygenase activity
CFBP6625_RS02970	COG1272	protein, Hemolysin III
CFBP6625_RS02980	COG1280	lysine exporter protein (LysE YggA)
CFBP6625_RS02985	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP6625_RS02990	COG2111	Na H antiporter
CFBP6625_RS02990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFBP6625_RS02995	COG2111	Na H antiporter
CFBP6625_RS03000	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP6625_RS03005	COG0651	ATP synthesis coupled electron transport
CFBP6625_RS03010	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP6625_RS03015	COG2212	antiporter activity
CFBP6625_RS03020	COG1320	monovalent cation:proton antiporter activity
CFBP6625_RS03025	COG4957	zinc ion binding
CFBP6625_RS03040	COG2166	iron-sulfur cluster assembly
CFBP6625_RS03050	COG2205	protein histidine kinase activity
CFBP6625_RS03095	COG0583	DNA-binding transcription factor activity
CFBP6625_RS03105	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP6625_RS03110	COG2983	Belongs to the UPF0260 family
CFBP6625_RS03120	COG2226	methyltransferase
CFBP6625_RS03125	COG2217	Heavy metal translocating P-type atpase
CFBP6625_RS03140	COG2337	Toxic component of a toxin-antitoxin (TA) module
CFBP6625_RS03160	COG1621	beta-fructofuranosidase activity
CFBP6625_RS03170	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFBP6625_RS03230	COG4695	Portal protein
CFBP6625_RS03345	COG4235	cytochrome complex assembly
CFBP6625_RS03350	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CFBP6625_RS03355	COG1138	Cytochrome C-type biogenesis protein
CFBP6625_RS03360	COG3088	subunit of a heme lyase
CFBP6625_RS03365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6625_RS03380	COG3011	Protein conserved in bacteria
CFBP6625_RS03390	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFBP6625_RS03400	COG2202	Pas domain
CFBP6625_RS03400	COG2205	protein histidine kinase activity
CFBP6625_RS03410	COG0308	aminopeptidase N
CFBP6625_RS03440	COG0443	Heat shock 70 kDa protein
CFBP6625_RS03450	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS03475	COG0604	alcohol dehydrogenase
CFBP6625_RS03480	COG1733	regulation of RNA biosynthetic process
CFBP6625_RS03485	COG1968	undecaprenyl-diphosphatase activity
CFBP6625_RS03490	COG2239	Acts as a magnesium transporter
CFBP6625_RS03495	COG2814	Major facilitator Superfamily
CFBP6625_RS03525	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFBP6625_RS03560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP6625_RS03600	COG0741	lytic transglycosylase activity
CFBP6625_RS03610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6625_RS03615	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFBP6625_RS03620	COG0840	transmembrane signaling receptor activity
CFBP6625_RS03630	COG1758	RNA polymerase activity
CFBP6625_RS03655	COG0736	holo-[acyl-carrier-protein] synthase activity
CFBP6625_RS03660	COG0681	Belongs to the peptidase S26 family
CFBP6625_RS03665	COG0571	ribonuclease III activity
CFBP6625_RS03670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFBP6625_RS03675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP6625_RS03680	COG0784	Response regulator, receiver
CFBP6625_RS03685	COG1381	Involved in DNA repair and RecF pathway recombination
CFBP6625_RS03695	COG2226	methyltransferase
CFBP6625_RS03705	COG1418	mRNA catabolic process
CFBP6625_RS03715	COG0346	lactoylglutathione lyase activity
CFBP6625_RS03725	COG1116	anion transmembrane transporter activity
CFBP6625_RS03730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6625_RS03735	COG3443	Belongs to the bacterial solute-binding protein 9 family
CFBP6625_RS03740	COG0668	transmembrane transport
CFBP6625_RS03750	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CFBP6625_RS03780	COG1742	UPF0060 membrane protein
CFBP6625_RS03795	COG1183	phosphatidylcholine synthase activity
CFBP6625_RS03800	COG0688	phosphatidylethanolamine metabolic process
CFBP6625_RS03805	COG5265	(ABC) transporter
CFBP6625_RS03850	COG2852	Protein conserved in bacteria
CFBP6625_RS03860	COG0215	cysteine-tRNA ligase activity
CFBP6625_RS03870	COG4221	oxidoreductase activity
CFBP6625_RS03875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFBP6625_RS03880	COG1286	toxin biosynthetic process
CFBP6625_RS03900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP6625_RS03910	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CFBP6625_RS03920	COG5265	(ABC) transporter
CFBP6625_RS03945	COG0359	binds to the 23S rRNA
CFBP6625_RS03955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFBP6625_RS03960	COG0360	Binds together with S18 to 16S ribosomal RNA
CFBP6625_RS03970	COG0667	Aldo Keto reductase
CFBP6625_RS03975	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CFBP6625_RS03985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6625_RS03990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP6625_RS04000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFBP6625_RS04005	COG1561	YicC-like family, N-terminal region
CFBP6625_RS04010	COG0194	GDP metabolic process
CFBP6625_RS04015	COG0400	carboxylic ester hydrolase activity
CFBP6625_RS04020	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFBP6625_RS04025	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP6625_RS04035	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CFBP6625_RS04050	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP6625_RS04070	COG4251	negative regulation of phosphorylation
CFBP6625_RS04070	COG2203	Gaf domain
CFBP6625_RS04070	COG3706	GGDEF domain
CFBP6625_RS04070	COG5001	Diguanylate cyclase
CFBP6625_RS04075	COG5001	Diguanylate cyclase
CFBP6625_RS04075	COG3300	MHYT domain
CFBP6625_RS04080	COG4191	Histidine kinase
CFBP6625_RS04095	COG0488	(ABC) transporter
CFBP6625_RS04100	COG3706	GGDEF domain
CFBP6625_RS04110	COG0105	UTP biosynthetic process
CFBP6625_RS04130	COG0314	molybdopterin synthase activity
CFBP6625_RS04140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFBP6625_RS04145	COG0322	excinuclease ABC activity
CFBP6625_RS04150	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS04160	COG0625	glutathione transferase activity
CFBP6625_RS04165	COG3719	Belongs to the RNase T2 family
CFBP6625_RS04175	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CFBP6625_RS04180	COG0243	molybdopterin cofactor binding
CFBP6625_RS04200	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFBP6625_RS04205	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFBP6625_RS04210	COG0628	permease
CFBP6625_RS04220	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CFBP6625_RS04225	COG0248	Ppx GppA phosphatase
CFBP6625_RS04230	COG0456	acetyltransferase
CFBP6625_RS04255	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CFBP6625_RS04265	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFBP6625_RS04270	COG0477	Major facilitator Superfamily
CFBP6625_RS04275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFBP6625_RS04285	COG0840	transmembrane signaling receptor activity
CFBP6625_RS04290	COG0659	secondary active sulfate transmembrane transporter activity
CFBP6625_RS04300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP6625_RS04305	COG3654	unkown
CFBP6625_RS04310	COG2336	PFAM SpoVT AbrB
CFBP6625_RS04315	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CFBP6625_RS04325	COG0113	porphobilinogen synthase activity
CFBP6625_RS04355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFBP6625_RS04360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFBP6625_RS04365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP6625_RS04365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP6625_RS04380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFBP6625_RS04385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFBP6625_RS04390	COG2814	Major facilitator Superfamily
CFBP6625_RS04395	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CFBP6625_RS04415	COG0416	fatty acid biosynthetic process
CFBP6625_RS04420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFBP6625_RS04425	COG0776	regulation of translation
CFBP6625_RS04460	COG0601	transmembrane transport
CFBP6625_RS04465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS04470	COG0444	Belongs to the ABC transporter superfamily
CFBP6625_RS04490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFBP6625_RS04495	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFBP6625_RS04510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFBP6625_RS04515	COG0583	DNA-binding transcription factor activity
CFBP6625_RS04525	COG0737	Belongs to the 5'-nucleotidase family
CFBP6625_RS04550	COG2897	thiosulfate sulfurtransferase activity
CFBP6625_RS04565	COG0415	Belongs to the DNA photolyase family
CFBP6625_RS04575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP6625_RS04605	COG3932	Exopolysaccharide synthesis, ExoD
CFBP6625_RS04610	COG1238	metal cluster binding
CFBP6625_RS04685	COG1612	heme a metabolic process
CFBP6625_RS04695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFBP6625_RS04700	COG0010	Belongs to the arginase family
CFBP6625_RS04705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFBP6625_RS04710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFBP6625_RS04725	COG1832	CoA-binding protein
CFBP6625_RS04740	COG2124	cytochrome p450
CFBP6625_RS04745	COG2199	diguanylate cyclase activity
CFBP6625_RS04750	COG0740	serine-type endopeptidase activity
CFBP6625_RS04755	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFBP6625_RS04765	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFBP6625_RS04775	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP6625_RS04805	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6625_RS04810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6625_RS04815	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6625_RS04825	COG0649	NAD binding
CFBP6625_RS04835	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CFBP6625_RS04840	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CFBP6625_RS04850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CFBP6625_RS04855	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP6625_RS04865	COG0713	ATP synthesis coupled electron transport
CFBP6625_RS04880	COG1007	ATP synthesis coupled electron transport
CFBP6625_RS04885	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CFBP6625_RS04885	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CFBP6625_RS04905	COG0442	prolyl-tRNA aminoacylation
CFBP6625_RS04915	COG1136	(ABC) transporter
CFBP6625_RS04935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP6625_RS04945	COG0784	Response regulator, receiver
CFBP6625_RS04955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFBP6625_RS04960	COG0477	Major facilitator Superfamily
CFBP6625_RS04975	COG0557	exoribonuclease II activity
CFBP6625_RS04980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFBP6625_RS04990	COG0758	DNA mediated transformation
CFBP6625_RS04995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CFBP6625_RS05000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CFBP6625_RS05005	COG0540	Belongs to the ATCase OTCase family
CFBP6625_RS05015	COG1960	acyl-CoA dehydrogenase activity
CFBP6625_RS05020	COG0456	acetyltransferase
CFBP6625_RS05040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFBP6625_RS05045	COG2824	Alkylphosphonate utilization operon protein PhnA
CFBP6625_RS05050	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CFBP6625_RS05055	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP6625_RS05060	COG0154	amidase activity
CFBP6625_RS05065	COG3811	Belongs to the UPF0386 family
CFBP6625_RS05080	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP6625_RS05090	COG0456	acetyltransferase
CFBP6625_RS05105	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CFBP6625_RS05110	COG0439	Biotin carboxylase
CFBP6625_RS05115	COG0511	ligase activity, forming carbon-carbon bonds
CFBP6625_RS05120	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP6625_RS05130	COG0436	Aminotransferase
CFBP6625_RS05135	COG0640	Transcriptional regulator
CFBP6625_RS05150	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS05155	COG1530	ribonuclease E activity
CFBP6625_RS05170	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP6625_RS05190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFBP6625_RS05195	COG0384	phenazine biosynthesis protein PhzF
CFBP6625_RS05210	COG0633	Ferredoxin
CFBP6625_RS05220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFBP6625_RS05225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFBP6625_RS05230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFBP6625_RS05240	COG3768	UPF0283 membrane protein
CFBP6625_RS05245	COG3106	COG3106 Predicted ATPase
CFBP6625_RS05275	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFBP6625_RS05310	COG0537	adenosine 5'-monophosphoramidase activity
CFBP6625_RS05335	COG0052	Belongs to the universal ribosomal protein uS2 family
CFBP6625_RS05340	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFBP6625_RS05345	COG0528	UMP kinase activity
CFBP6625_RS05350	COG0233	cytoplasmic translational termination
CFBP6625_RS05355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFBP6625_RS05365	COG0750	zinc metalloprotease
CFBP6625_RS05370	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP6625_RS05375	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP6625_RS05380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP6625_RS05385	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP6625_RS05390	COG3494	Protein of unknown function (DUF1009)
CFBP6625_RS05395	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP6625_RS05400	COG0372	Belongs to the citrate synthase family
CFBP6625_RS05420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFBP6625_RS05430	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CFBP6625_RS05435	COG0148	phosphopyruvate hydratase activity
CFBP6625_RS05445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFBP6625_RS05450	COG0022	dehydrogenase e1 component
CFBP6625_RS05450	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP6625_RS05455	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP6625_RS05465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFBP6625_RS05475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFBP6625_RS05480	COG0697	spore germination
CFBP6625_RS05495	COG2867	negative regulation of translational initiation
CFBP6625_RS05505	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFBP6625_RS05505	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFBP6625_RS05515	COG3852	Histidine kinase
CFBP6625_RS05520	COG2204	response regulator
CFBP6625_RS05525	COG5000	phosphorelay sensor kinase activity
CFBP6625_RS05530	COG2204	response regulator
CFBP6625_RS05535	COG0569	domain protein
CFBP6625_RS05540	COG1923	regulation of RNA biosynthetic process
CFBP6625_RS05545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFBP6625_RS05550	COG3956	TIGRFAM MazG family protein
CFBP6625_RS05565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP6625_RS05565	COG1648	precorrin-2 dehydrogenase activity
CFBP6625_RS05595	COG3706	GGDEF domain
CFBP6625_RS05605	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP6625_RS05605	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP6625_RS05610	COG0509	glycine decarboxylation via glycine cleavage system
CFBP6625_RS05615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP6625_RS05640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFBP6625_RS05645	COG0564	pseudouridine synthase activity
CFBP6625_RS05650	COG0546	phosphoglycolate phosphatase activity
CFBP6625_RS05665	COG1309	transcriptional regulator
CFBP6625_RS05670	COG0251	oxidation-reduction process
CFBP6625_RS05675	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CFBP6625_RS05685	COG1671	Belongs to the UPF0178 family
CFBP6625_RS05700	COG0450	alkyl hydroperoxide reductase
CFBP6625_RS05705	COG0625	glutathione transferase activity
CFBP6625_RS05715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP6625_RS05720	COG0328	RNA-DNA hybrid ribonuclease activity
CFBP6625_RS05730	COG1595	DNA-templated transcription, initiation
CFBP6625_RS05740	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CFBP6625_RS05745	COG0431	NADPH-dependent FMN reductase
CFBP6625_RS05755	COG0798	PFAM Bile acid sodium symporter
CFBP6625_RS05765	COG2226	methyltransferase
CFBP6625_RS05770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS05775	COG0601	transmembrane transport
CFBP6625_RS05795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CFBP6625_RS05795	COG0321	lipoyl(octanoyl) transferase activity
CFBP6625_RS05800	COG0084	hydrolase, TatD family'
CFBP6625_RS05805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP6625_RS05815	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFBP6625_RS05880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP6625_RS05885	COG2095	MarC family integral membrane protein
CFBP6625_RS05890	COG0617	tRNA 3'-terminal CCA addition
CFBP6625_RS05890	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CFBP6625_RS05890	COG0517	IMP dehydrogenase activity
CFBP6625_RS05895	COG0629	single-stranded DNA binding
CFBP6625_RS05900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFBP6625_RS05910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFBP6625_RS05915	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFBP6625_RS05930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP6625_RS05935	COG1121	(ABC) transporter
CFBP6625_RS05955	COG0667	Aldo Keto reductase
CFBP6625_RS05965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFBP6625_RS06045	COG2239	Acts as a magnesium transporter
CFBP6625_RS06050	COG0243	molybdopterin cofactor binding
CFBP6625_RS06060	COG0242	peptide deformylase activity
CFBP6625_RS06075	COG2205	protein histidine kinase activity
CFBP6625_RS06075	COG2202	Pas domain
CFBP6625_RS06090	COG0321	lipoyl(octanoyl) transferase activity
CFBP6625_RS06095	COG1064	alcohol dehydrogenase
CFBP6625_RS06125	COG1862	Preprotein translocase
CFBP6625_RS06135	COG1045	serine acetyltransferase
CFBP6625_RS06165	COG0596	Alpha beta hydrolase
CFBP6625_RS06340	COG3772	lysozyme
CFBP6625_RS06360	COG0626	cystathionine gamma-synthase activity
CFBP6625_RS06365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6625_RS06370	COG4597	amino acid ABC transporter
CFBP6625_RS06375	COG0765	amino acid transport
CFBP6625_RS06380	COG1126	abc transporter atp-binding protein
CFBP6625_RS06395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFBP6625_RS06410	COG0436	Aminotransferase
CFBP6625_RS06440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP6625_RS06450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP6625_RS06455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6625_RS06460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP6625_RS06475	COG3243	poly(R)-hydroxyalkanoic acid synthase
CFBP6625_RS06480	COG1489	DNA binding
CFBP6625_RS06485	COG0024	Methionine aminopeptidase
CFBP6625_RS06490	COG2003	Belongs to the UPF0758 family
CFBP6625_RS06505	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CFBP6625_RS06520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFBP6625_RS06525	COG0546	phosphoglycolate phosphatase activity
CFBP6625_RS06535	COG0114	fumarate hydratase activity
CFBP6625_RS06545	COG0504	CTP synthase activity
CFBP6625_RS06555	COG0149	triose-phosphate isomerase activity
CFBP6625_RS06565	COG0187	DNA topoisomerase II activity
CFBP6625_RS06575	COG0740	serine-type endopeptidase activity
CFBP6625_RS06585	COG0640	Transcriptional regulator
CFBP6625_RS06590	COG0840	transmembrane signaling receptor activity
CFBP6625_RS06595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFBP6625_RS06600	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS06625	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CFBP6625_RS06625	COG3264	Mechanosensitive ion channel
CFBP6625_RS06645	COG1396	sequence-specific DNA binding
CFBP6625_RS06925	COG1127	ABC transporter
CFBP6625_RS06930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFBP6625_RS06935	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6625_RS06945	COG0281	malic enzyme
CFBP6625_RS06945	COG0280	phosphate acetyltransferase
CFBP6625_RS06955	COG0778	Nitroreductase
CFBP6625_RS06960	COG0823	Involved in the tonB-independent uptake of proteins
CFBP6625_RS06975	COG1368	sulfuric ester hydrolase activity
CFBP6625_RS07000	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFBP6625_RS07025	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFBP6625_RS07045	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFBP6625_RS07075	COG0512	Glutamine amidotransferase of anthranilate synthase
CFBP6625_RS07075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFBP6625_RS07080	COG0343	queuine tRNA-ribosyltransferase activity
CFBP6625_RS07085	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFBP6625_RS07100	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFBP6625_RS07125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFBP6625_RS07130	COG0134	indole-3-glycerol-phosphate synthase activity
CFBP6625_RS07135	COG0315	cyclic pyranopterin monophosphate synthase activity
CFBP6625_RS07140	COG0303	'Molybdopterin
CFBP6625_RS07145	COG3706	GGDEF domain
CFBP6625_RS07155	COG0475	glutathione-regulated potassium exporter activity
CFBP6625_RS07155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP6625_RS07165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFBP6625_RS07175	COG2814	Major facilitator Superfamily
CFBP6625_RS07180	COG0746	molybdenum cofactor guanylyltransferase activity
CFBP6625_RS07185	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFBP6625_RS07190	COG0739	heme binding
CFBP6625_RS07195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP6625_RS07200	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CFBP6625_RS07205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP6625_RS07210	COG0805	protein transport
CFBP6625_RS07215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP6625_RS07220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP6625_RS07225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFBP6625_RS07230	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFBP6625_RS07235	COG1472	Belongs to the glycosyl hydrolase 3 family
CFBP6625_RS07245	COG0018	arginyl-trna synthetase
CFBP6625_RS07250	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CFBP6625_RS07255	COG0316	Belongs to the HesB IscA family
CFBP6625_RS07285	COG0525	valine-tRNA ligase activity
CFBP6625_RS07295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP6625_RS07330	COG0655	NAD(P)H dehydrogenase (quinone) activity
CFBP6625_RS07335	COG1546	Belongs to the CinA family
CFBP6625_RS07335	COG1058	Belongs to the CinA family
CFBP6625_RS07340	COG0589	response to stress
CFBP6625_RS07345	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CFBP6625_RS07355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFBP6625_RS07370	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP6625_RS07385	COG1132	(ABC) transporter
CFBP6625_RS07390	COG0628	permease
CFBP6625_RS07425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFBP6625_RS07435	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFBP6625_RS07445	COG0302	gtp cyclohydrolase
CFBP6625_RS07450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFBP6625_RS07455	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP6625_RS07465	COG0517	IMP dehydrogenase activity
CFBP6625_RS07465	COG0516	GMP reductase activity
CFBP6625_RS07500	COG1760	l-serine dehydratase
CFBP6625_RS07535	COG0583	DNA-binding transcription factor activity
CFBP6625_RS07550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFBP6625_RS07550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFBP6625_RS07555	COG0347	Belongs to the P(II) protein family
CFBP6625_RS07560	COG0174	glutamine synthetase
CFBP6625_RS07590	COG0697	spore germination
CFBP6625_RS07600	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFBP6625_RS07615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFBP6625_RS07625	COG3668	Plasmid stabilization system
CFBP6625_RS07630	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFBP6625_RS07645	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP6625_RS07650	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFBP6625_RS07655	COG2186	Transcriptional regulator
CFBP6625_RS07665	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS07670	COG4603	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS07675	COG3845	ABC transporter
CFBP6625_RS07680	COG1183	phosphatidylcholine synthase activity
CFBP6625_RS07685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP6625_RS07690	COG0679	Auxin Efflux Carrier
CFBP6625_RS07695	COG0785	Cytochrome C biogenesis protein
CFBP6625_RS07715	COG0346	lactoylglutathione lyase activity
CFBP6625_RS07720	COG1278	Cold shock
CFBP6625_RS07810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6625_RS07830	COG2755	lipolytic protein G-D-S-L family
CFBP6625_RS07830	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP6625_RS07880	COG0393	Putative heavy-metal-binding
CFBP6625_RS07940	COG0616	signal peptide processing
CFBP6625_RS08000	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CFBP6625_RS08040	COG1061	Type III restriction enzyme res subunit
CFBP6625_RS08140	COG0582	viral genome integration into host DNA
CFBP6625_RS08165	COG1073	alpha beta
CFBP6625_RS08180	COG0667	Aldo Keto reductase
CFBP6625_RS08190	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS08195	COG1175	transmembrane transport
CFBP6625_RS08200	COG3842	ATPase activity
CFBP6625_RS08205	COG1737	Transcriptional regulator
CFBP6625_RS08220	COG0577	efflux transmembrane transporter activity
CFBP6625_RS08220	COG1136	(ABC) transporter
CFBP6625_RS08225	COG0577	efflux transmembrane transporter activity
CFBP6625_RS08225	COG1136	(ABC) transporter
CFBP6625_RS08240	COG2151	metal-sulfur cluster biosynthetic enzyme
CFBP6625_RS08245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFBP6625_RS08250	COG0719	Fe-S assembly protein
CFBP6625_RS08255	COG0396	ATPase activity
CFBP6625_RS08265	COG0719	Fe-S assembly protein
CFBP6625_RS08270	COG1104	cysteine desulfurase activity
CFBP6625_RS08275	COG2945	thiolester hydrolase activity
CFBP6625_RS08285	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFBP6625_RS08290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFBP6625_RS08300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFBP6625_RS08305	COG2833	Protein of unknown function (DUF455)
CFBP6625_RS08310	COG0739	heme binding
CFBP6625_RS08315	COG0513	Belongs to the DEAD box helicase family
CFBP6625_RS08345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFBP6625_RS08355	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP6625_RS08360	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP6625_RS08365	COG0047	phosphoribosylformylglycinamidine synthase activity
CFBP6625_RS08385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6625_RS08395	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP6625_RS08415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CFBP6625_RS08420	COG2814	Major facilitator Superfamily
CFBP6625_RS08425	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6625_RS08430	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6625_RS08435	COG0037	tRNA processing
CFBP6625_RS08440	COG2066	Belongs to the glutaminase family
CFBP6625_RS08445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFBP6625_RS08450	COG0861	Integral membrane protein TerC family
CFBP6625_RS08465	COG1280	lysine exporter protein (LysE YggA)
CFBP6625_RS08470	COG3093	addiction module antidote protein HigA
CFBP6625_RS08480	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFBP6625_RS08485	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CFBP6625_RS08495	COG0538	isocitrate dehydrogenase activity
CFBP6625_RS08520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFBP6625_RS08525	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFBP6625_RS08535	COG2313	pseudouridylate synthase activity
CFBP6625_RS08550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6625_RS08555	COG4215	(ABC) transporter
CFBP6625_RS08565	COG5425	PFAM Usg family protein
CFBP6625_RS08575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6625_RS08580	COG1522	sequence-specific DNA binding
CFBP6625_RS08585	COG1573	uracil-dna glycosylase
CFBP6625_RS08595	COG2202	Pas domain
CFBP6625_RS08595	COG2205	protein histidine kinase activity
CFBP6625_RS08605	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CFBP6625_RS08610	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CFBP6625_RS08625	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP6625_RS08630	COG0842	Transport permease protein
CFBP6625_RS08635	COG1131	(ABC) transporter
CFBP6625_RS08640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6625_RS08640	COG0730	response to heat
CFBP6625_RS08650	COG0840	transmembrane signaling receptor activity
CFBP6625_RS08650	COG0840	transmembrane signaling receptor activity
CFBP6625_RS08660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFBP6625_RS08665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP6625_RS08680	COG0129	dihydroxy-acid dehydratase activity
CFBP6625_RS08685	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFBP6625_RS08690	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CFBP6625_RS08700	COG3739	integral membrane protein
CFBP6625_RS08715	COG0203	ribosomal protein L17
CFBP6625_RS08720	COG0202	RNA polymerase activity
CFBP6625_RS08725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFBP6625_RS08730	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFBP6625_RS08735	COG0563	adenylate kinase activity
CFBP6625_RS08740	COG0201	protein transport
CFBP6625_RS08745	COG0200	Binds to the 23S rRNA
CFBP6625_RS08750	COG1841	ribosomal large subunit assembly
CFBP6625_RS08755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFBP6625_RS08760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFBP6625_RS08765	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFBP6625_RS08770	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFBP6625_RS08775	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFBP6625_RS08780	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFBP6625_RS08785	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFBP6625_RS08790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFBP6625_RS08795	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFBP6625_RS08800	COG0255	Belongs to the universal ribosomal protein uL29 family
CFBP6625_RS08805	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFBP6625_RS08810	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFBP6625_RS08815	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFBP6625_RS08820	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFBP6625_RS08825	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFBP6625_RS08830	COG0089	rRNA binding
CFBP6625_RS08835	COG0088	Forms part of the polypeptide exit tunnel
CFBP6625_RS08840	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFBP6625_RS08845	COG0051	transcription antitermination factor activity, RNA binding
CFBP6625_RS08850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP6625_RS08855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFBP6625_RS08860	COG0049	tRNA binding
CFBP6625_RS08865	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFBP6625_RS08885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFBP6625_RS08890	COG0085	RNA polymerase activity
CFBP6625_RS08895	COG0222	ribosome binding
CFBP6625_RS08900	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFBP6625_RS08905	COG0081	regulation of translation
CFBP6625_RS08910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFBP6625_RS08920	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CFBP6625_RS08935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP6625_RS08940	COG0861	Integral membrane protein TerC family
CFBP6625_RS08990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP6625_RS09015	COG1132	(ABC) transporter
CFBP6625_RS09030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP6625_RS09035	COG1607	acyl-coa hydrolase
CFBP6625_RS09060	COG2910	NAD(P)H-binding
CFBP6625_RS09065	COG1733	regulation of RNA biosynthetic process
CFBP6625_RS09080	COG0556	nucleotide-excision repair
CFBP6625_RS09090	COG2382	esterase
CFBP6625_RS09110	COG0484	heat shock protein binding
CFBP6625_RS09135	COG3842	ATPase activity
CFBP6625_RS09145	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6625_RS09155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6625_RS09170	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFBP6625_RS09180	COG2207	Transcriptional regulator
CFBP6625_RS09185	COG1064	alcohol dehydrogenase
CFBP6625_RS09190	COG1252	NADH dehydrogenase
CFBP6625_RS09195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFBP6625_RS09205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP6625_RS09240	COG0656	L-ascorbic acid biosynthetic process
CFBP6625_RS09260	COG0440	acetolactate synthase activity
CFBP6625_RS09265	COG0028	Belongs to the TPP enzyme family
CFBP6625_RS09275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFBP6625_RS09300	COG0330	HflC and HflK could
CFBP6625_RS09305	COG0330	HflC and HflK could
CFBP6625_RS09315	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFBP6625_RS09355	COG0277	FAD linked oxidase domain protein
CFBP6625_RS09360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6625_RS09415	COG1335	isochorismatase
CFBP6625_RS09435	COG0006	proline dipeptidase activity
CFBP6625_RS09445	COG2264	protein methyltransferase activity
CFBP6625_RS09450	COG1999	signal sequence binding
CFBP6625_RS09460	COG0835	chemotaxis
CFBP6625_RS09470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFBP6625_RS09475	COG0583	DNA-binding transcription factor activity
CFBP6625_RS09485	COG1247	-acetyltransferase
CFBP6625_RS09495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFBP6625_RS09500	COG1280	lysine exporter protein (LysE YggA)
CFBP6625_RS09505	COG0497	DNA recombination
CFBP6625_RS09510	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP6625_RS09520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP6625_RS09525	COG0849	cell division
CFBP6625_RS09530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFBP6625_RS09535	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFBP6625_RS09540	COG0477	Major facilitator Superfamily
CFBP6625_RS09550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFBP6625_RS09555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFBP6625_RS09560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFBP6625_RS09570	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFBP6625_RS09575	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFBP6625_RS09585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFBP6625_RS09600	COG0275	rRNA processing
CFBP6625_RS09605	COG2001	Belongs to the MraZ family
CFBP6625_RS09630	COG3023	N-Acetylmuramoyl-L-alanine amidase
CFBP6625_RS09660	COG4106	trans-aconitate 2-methyltransferase activity
CFBP6625_RS09680	COG2226	methyltransferase
CFBP6625_RS09690	COG2267	carboxylic ester hydrolase activity
CFBP6625_RS09695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP6625_RS09725	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6625_RS09730	COG2814	Major facilitator Superfamily
CFBP6625_RS09755	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS09760	COG0174	glutamine synthetase
CFBP6625_RS09765	COG0531	amino acid
CFBP6625_RS09775	COG1737	Transcriptional regulator
CFBP6625_RS09800	COG3842	ATPase activity
CFBP6625_RS09860	COG2968	Membrane
CFBP6625_RS09870	COG0432	Pfam Uncharacterised protein family UPF0047
CFBP6625_RS09890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP6625_RS09895	COG0358	DNA primase activity
CFBP6625_RS09910	COG0505	Belongs to the CarA family
CFBP6625_RS09915	COG0534	Mate efflux family protein
CFBP6625_RS09930	COG2321	neutral zinc metallopeptidase
CFBP6625_RS09945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFBP6625_RS09955	COG3706	GGDEF domain
CFBP6625_RS09960	COG1573	uracil-dna glycosylase
CFBP6625_RS09970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFBP6625_RS09980	COG1522	sequence-specific DNA binding
CFBP6625_RS09985	COG0492	ferredoxin-NADP+ reductase activity
CFBP6625_RS09990	COG0583	DNA-binding transcription factor activity
CFBP6625_RS10000	COG1902	pentaerythritol trinitrate reductase activity
CFBP6625_RS10030	COG0387	Pfam Sodium calcium exchanger
CFBP6625_RS10035	COG0436	Aminotransferase
CFBP6625_RS10040	COG2200	EAL domain
CFBP6625_RS10040	COG2199	diguanylate cyclase activity
CFBP6625_RS10060	COG1278	Cold shock
CFBP6625_RS10065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6625_RS10080	COG1846	Transcriptional regulator
CFBP6625_RS10085	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS10090	COG2205	protein histidine kinase activity
CFBP6625_RS10095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP6625_RS10115	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFBP6625_RS10125	COG1496	oxidoreductase activity
CFBP6625_RS10140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFBP6625_RS10165	COG0840	transmembrane signaling receptor activity
CFBP6625_RS10170	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS10180	COG5001	Diguanylate cyclase
CFBP6625_RS10180	COG3300	MHYT domain
CFBP6625_RS10185	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFBP6625_RS10190	COG5001	Diguanylate cyclase
CFBP6625_RS10200	COG0193	aminoacyl-tRNA hydrolase activity
CFBP6625_RS10215	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFBP6625_RS10240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFBP6625_RS10250	COG2857	Cytochrome c1
CFBP6625_RS10250	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CFBP6625_RS10270	COG0840	transmembrane signaling receptor activity
CFBP6625_RS10275	COG1132	(ABC) transporter
CFBP6625_RS10280	COG1132	(ABC) transporter
CFBP6625_RS10285	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CFBP6625_RS10290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFBP6625_RS10305	COG0408	coproporphyrinogen oxidase activity
CFBP6625_RS10320	COG0617	tRNA 3'-terminal CCA addition
CFBP6625_RS10335	COG0714	Associated with various cellular activities
CFBP6625_RS10355	COG0454	-acetyltransferase
CFBP6625_RS10370	COG0477	Major facilitator Superfamily
CFBP6625_RS10385	COG0435	Glutathione S-transferase
CFBP6625_RS10400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFBP6625_RS10405	COG3135	benzoate transporter
CFBP6625_RS10415	COG4944	Protein of unknown function (DUF1109)
CFBP6625_RS10430	COG0740	serine-type endopeptidase activity
CFBP6625_RS10445	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFBP6625_RS10450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFBP6625_RS10480	COG4175	Glycine betaine
CFBP6625_RS10495	COG1435	thymidine kinase activity
CFBP6625_RS10510	COG2197	response regulator
CFBP6625_RS10515	COG2862	Uncharacterized protein family, UPF0114
CFBP6625_RS10520	COG4771	TonB-dependent receptor
CFBP6625_RS10520	COG1629	transport
CFBP6625_RS10530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFBP6625_RS10530	COG0512	Glutamine amidotransferase of anthranilate synthase
CFBP6625_RS10545	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP6625_RS10560	COG0366	Alpha amylase catalytic
CFBP6625_RS10565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6625_RS10590	COG1160	GTP binding
CFBP6625_RS10610	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CFBP6625_RS10625	COG0024	Methionine aminopeptidase
CFBP6625_RS10640	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS10655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFBP6625_RS10665	COG0583	DNA-binding transcription factor activity
CFBP6625_RS10680	COG0402	S-adenosylhomocysteine deaminase activity
CFBP6625_RS10690	COG1304	FMN binding
CFBP6625_RS10700	COG1309	transcriptional regulator
CFBP6625_RS10705	COG1686	Belongs to the peptidase S11 family
CFBP6625_RS10715	COG2351	hydroxyisourate hydrolase activity
CFBP6625_RS10720	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CFBP6625_RS10735	COG3648	Uricase
CFBP6625_RS10735	COG3195	allantoin biosynthetic process
CFBP6625_RS10745	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP6625_RS10755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS10755	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFBP6625_RS10760	COG0784	Response regulator, receiver
CFBP6625_RS10760	COG2205	protein histidine kinase activity
CFBP6625_RS10760	COG5002	protein histidine kinase activity
CFBP6625_RS10765	COG0513	Belongs to the DEAD box helicase family
CFBP6625_RS10775	COG2259	Doxx family
CFBP6625_RS10780	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6625_RS10790	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP6625_RS10800	COG1305	Transglutaminase-like
CFBP6625_RS10825	COG4214	carbohydrate transport
CFBP6625_RS10835	COG4213	ABC transporter substrate-binding protein
CFBP6625_RS10875	COG1309	transcriptional regulator
CFBP6625_RS10890	COG0840	transmembrane signaling receptor activity
CFBP6625_RS10890	COG2972	Histidine kinase
CFBP6625_RS10915	COG1215	transferase activity, transferring glycosyl groups
CFBP6625_RS10930	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CFBP6625_RS10940	COG0489	protein tyrosine kinase activity
CFBP6625_RS10940	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP6625_RS10950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP6625_RS10965	COG2346	COG2346, Truncated hemoglobins
CFBP6625_RS10985	COG1309	transcriptional regulator
CFBP6625_RS11005	COG0494	nUDIX hydrolase
CFBP6625_RS11020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6625_RS11025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6625_RS11050	COG1234	tRNA 3'-trailer cleavage
CFBP6625_RS11055	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFBP6625_RS11060	COG0830	nickel cation binding
CFBP6625_RS11065	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CFBP6625_RS11080	COG0804	urea catabolic process
CFBP6625_RS11085	COG1442	glycosyl transferase family 8
CFBP6625_RS11090	COG3755	Protein conserved in bacteria
CFBP6625_RS11100	COG0832	Belongs to the urease beta subunit family
CFBP6625_RS11105	COG3813	Protein conserved in bacteria
CFBP6625_RS11110	COG0831	urea catabolic process
CFBP6625_RS11115	COG0829	nickel cation binding
CFBP6625_RS11145	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS11165	COG0174	glutamine synthetase
CFBP6625_RS11170	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS11175	COG0784	Response regulator, receiver
CFBP6625_RS11175	COG5002	protein histidine kinase activity
CFBP6625_RS11175	COG2198	Histidine kinase
CFBP6625_RS11220	COG1218	3'(2'),5'-bisphosphate nucleotidase
CFBP6625_RS11295	COG0564	pseudouridine synthase activity
CFBP6625_RS11305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP6625_RS11320	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFBP6625_RS11400	COG4396	Host-nuclease inhibitor protein Gam
CFBP6625_RS11465	COG2369	cell adhesion
CFBP6625_RS11470	COG5005	Phage virion morphogenesis
CFBP6625_RS11615	COG0346	lactoylglutathione lyase activity
CFBP6625_RS11625	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFBP6625_RS11635	COG2832	Protein of unknown function (DUF454)
CFBP6625_RS11640	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFBP6625_RS11645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6625_RS11650	COG4558	Periplasmic binding protein
CFBP6625_RS11660	COG3721	Heme iron utilization protein
CFBP6625_RS11675	COG2205	protein histidine kinase activity
CFBP6625_RS11720	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6625_RS11725	COG4605	iron ion homeostasis
CFBP6625_RS11730	COG4604	ABC transporter, ATP-binding protein
CFBP6625_RS11735	COG0783	Belongs to the Dps family
CFBP6625_RS11755	COG2814	Major facilitator Superfamily
CFBP6625_RS11760	COG0583	DNA-binding transcription factor activity
CFBP6625_RS11765	COG0583	DNA-binding transcription factor activity
CFBP6625_RS11770	COG0657	acetylesterase activity
CFBP6625_RS11775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS11795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFBP6625_RS11800	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CFBP6625_RS11805	COG0288	reversible hydration of carbon dioxide
CFBP6625_RS11815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFBP6625_RS11835	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CFBP6625_RS11840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP6625_RS11845	COG0778	Nitroreductase
CFBP6625_RS11850	COG2267	carboxylic ester hydrolase activity
CFBP6625_RS11855	COG0251	oxidation-reduction process
CFBP6625_RS11860	COG1335	isochorismatase
CFBP6625_RS11865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS11875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6625_RS11890	COG1175	transmembrane transport
CFBP6625_RS11895	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS11900	COG3842	ATPase activity
CFBP6625_RS11905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6625_RS11915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP6625_RS11930	COG4608	Belongs to the ABC transporter superfamily
CFBP6625_RS11935	COG0444	Belongs to the ABC transporter superfamily
CFBP6625_RS11940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS11945	COG0601	transmembrane transport
CFBP6625_RS11980	COG2814	Major facilitator Superfamily
CFBP6625_RS12000	COG2159	amidohydrolase
CFBP6625_RS12005	COG1960	acyl-CoA dehydrogenase activity
CFBP6625_RS12035	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS12045	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP6625_RS12045	COG1902	pentaerythritol trinitrate reductase activity
CFBP6625_RS12055	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS12065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFBP6625_RS12065	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFBP6625_RS12075	COG1388	LysM domain
CFBP6625_RS12075	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6625_RS12080	COG3842	ATPase activity
CFBP6625_RS12090	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6625_RS12095	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6625_RS12105	COG0784	Response regulator, receiver
CFBP6625_RS12105	COG4191	Histidine kinase
CFBP6625_RS12110	COG0662	Cupin 2, conserved barrel domain protein
CFBP6625_RS12110	COG2207	Transcriptional regulator
CFBP6625_RS12115	COG0667	Aldo Keto reductase
CFBP6625_RS12120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFBP6625_RS12125	COG0583	DNA-binding transcription factor activity
CFBP6625_RS12145	COG1484	DNA-dependent DNA replication
CFBP6625_RS12150	COG2390	Transcriptional regulator
CFBP6625_RS12150	COG4584	PFAM Integrase catalytic
CFBP6625_RS12195	COG1175	transmembrane transport
CFBP6625_RS12200	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS12205	COG1063	alcohol dehydrogenase
CFBP6625_RS12210	COG3842	ATPase activity
CFBP6625_RS12215	COG1454	alcohol dehydrogenase
CFBP6625_RS12225	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS12240	COG3842	ATPase activity
CFBP6625_RS12245	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS12250	COG1175	transmembrane transport
CFBP6625_RS12260	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6625_RS12265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6625_RS12270	COG3734	2-keto-3-deoxy-galactonokinase
CFBP6625_RS12285	COG3436	PFAM IS66 Orf2 family protein
CFBP6625_RS12290	COG4372	Transposase
CFBP6625_RS12340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP6625_RS12350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS12355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6625_RS12365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFBP6625_RS12370	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CFBP6625_RS12375	COG1509	lysine 2,3-aminomutase activity
CFBP6625_RS12390	COG0583	DNA-binding transcription factor activity
CFBP6625_RS12395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS12400	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFBP6625_RS12405	COG4149	molybdate abc transporter
CFBP6625_RS12410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CFBP6625_RS12425	COG2022	thiamine diphosphate biosynthetic process
CFBP6625_RS12440	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFBP6625_RS12445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6625_RS12455	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP6625_RS12475	COG1132	(ABC) transporter
CFBP6625_RS12480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP6625_RS12505	COG0438	transferase activity, transferring glycosyl groups
CFBP6625_RS12525	COG4166	transmembrane transport
CFBP6625_RS12530	COG0601	transmembrane transport
CFBP6625_RS12535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS12545	COG0438	transferase activity, transferring glycosyl groups
CFBP6625_RS12550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFBP6625_RS12555	COG3142	Participates in the control of copper homeostasis
CFBP6625_RS12575	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS12580	COG1737	Transcriptional regulator
CFBP6625_RS12590	COG3842	ATPase activity
CFBP6625_RS12600	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS12620	COG2188	Transcriptional regulator
CFBP6625_RS12625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP6625_RS12630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFBP6625_RS12635	COG1940	carbohydrate kinase activity
CFBP6625_RS12645	COG0671	phosphoesterase, PA-phosphatase related
CFBP6625_RS12650	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFBP6625_RS12655	COG0156	8-amino-7-oxononanoate synthase activity
CFBP6625_RS12665	COG0729	surface antigen
CFBP6625_RS12675	COG0835	chemotaxis
CFBP6625_RS12685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFBP6625_RS12690	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFBP6625_RS12695	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFBP6625_RS12700	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFBP6625_RS12705	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFBP6625_RS12710	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFBP6625_RS12725	COG4974	Belongs to the 'phage' integrase family
CFBP6625_RS12750	COG1280	lysine exporter protein (LysE YggA)
CFBP6625_RS12760	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP6625_RS12770	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFBP6625_RS12775	COG0045	succinate-CoA ligase (ADP-forming) activity
CFBP6625_RS12780	COG0039	L-malate dehydrogenase activity
CFBP6625_RS12785	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFBP6625_RS12820	COG2264	protein methyltransferase activity
CFBP6625_RS12835	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFBP6625_RS12840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFBP6625_RS12845	COG0181	hydroxymethylbilane synthase activity
CFBP6625_RS12880	COG1872	DUF167
CFBP6625_RS12885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFBP6625_RS12895	COG1217	gtp-binding protein TYPA
CFBP6625_RS12900	COG0339	signal peptide processing
CFBP6625_RS12910	COG1846	Transcriptional regulator
CFBP6625_RS12920	COG0137	argininosuccinate synthase activity
CFBP6625_RS12930	COG1280	lysine exporter protein (LysE YggA)
CFBP6625_RS12935	COG1122	ATPase activity
CFBP6625_RS12940	COG4120	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS12950	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CFBP6625_RS12965	COG2154	pterin-4-alpha-carbinolamine dehydratase
CFBP6625_RS12970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFBP6625_RS12975	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CFBP6625_RS12985	COG4181	ATPase activity
CFBP6625_RS12995	COG0670	Belongs to the BI1 family
CFBP6625_RS13010	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFBP6625_RS13015	COG4133	protoheme IX ABC transporter activity
CFBP6625_RS13025	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP6625_RS13030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP6625_RS13055	COG2917	probably involved in intracellular septation
CFBP6625_RS13060	COG0552	protein localization to endoplasmic reticulum
CFBP6625_RS13065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP6625_RS13070	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFBP6625_RS13085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFBP6625_RS13090	COG1605	Chorismate mutase
CFBP6625_RS13090	COG0287	Prephenate dehydrogenase
CFBP6625_RS13095	COG0228	four-way junction DNA binding
CFBP6625_RS13100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFBP6625_RS13105	COG0336	Belongs to the RNA methyltransferase TrmD family
CFBP6625_RS13115	COG0335	large ribosomal subunit rRNA binding
CFBP6625_RS13120	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP6625_RS13125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS13145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFBP6625_RS13160	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFBP6625_RS13180	COG0488	(ABC) transporter
CFBP6625_RS13190	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CFBP6625_RS13200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFBP6625_RS13205	COG0142	geranyltranstransferase activity
CFBP6625_RS13210	COG2885	chlorophyll binding
CFBP6625_RS13215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFBP6625_RS13220	COG2223	nitrite transmembrane transporter activity
CFBP6625_RS13225	COG1349	DNA-binding transcription factor activity
CFBP6625_RS13230	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFBP6625_RS13235	COG2197	response regulator
CFBP6625_RS13240	COG1132	(ABC) transporter
CFBP6625_RS13245	COG3459	Glycosyltransferase 36 associated
CFBP6625_RS13250	COG1473	amidohydrolase
CFBP6625_RS13260	COG0579	oxidoreductase
CFBP6625_RS13270	COG0129	dihydroxy-acid dehydratase activity
CFBP6625_RS13275	COG2084	Dehydrogenase
CFBP6625_RS13280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6625_RS13285	COG0277	FAD linked oxidase domain protein
CFBP6625_RS13290	COG2186	Transcriptional regulator
CFBP6625_RS13300	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP6625_RS13305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6625_RS13310	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6625_RS13315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP6625_RS13325	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFBP6625_RS13330	COG0495	leucyl-tRNA aminoacylation
CFBP6625_RS13345	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFBP6625_RS13350	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFBP6625_RS13365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP6625_RS13370	COG1946	Acyl-CoA thioesterase
CFBP6625_RS13375	COG0347	Belongs to the P(II) protein family
CFBP6625_RS13380	COG0004	ammonium transporteR
CFBP6625_RS13385	COG1674	ftsk spoiiie
CFBP6625_RS13390	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CFBP6625_RS13405	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS13415	COG1329	Transcriptional regulator
CFBP6625_RS13420	COG2902	Dehydrogenase
CFBP6625_RS13425	COG2270	Major facilitator Superfamily
CFBP6625_RS13440	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS13455	COG0494	nUDIX hydrolase
CFBP6625_RS13465	COG0793	Belongs to the peptidase S41A family
CFBP6625_RS13475	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFBP6625_RS13480	COG0799	negative regulation of ribosome biogenesis
CFBP6625_RS13485	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFBP6625_RS13490	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFBP6625_RS13495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFBP6625_RS13500	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFBP6625_RS13515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFBP6625_RS13520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFBP6625_RS13545	COG0066	3-isopropylmalate dehydratase activity
CFBP6625_RS13550	COG0473	3-isopropylmalate dehydrogenase activity
CFBP6625_RS13555	COG1858	cytochrome C peroxidase
CFBP6625_RS13560	COG1797	cobyrinic acid a,c-diamide synthase activity
CFBP6625_RS13565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP6625_RS13565	COG1648	precorrin-2 dehydrogenase activity
CFBP6625_RS13570	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CFBP6625_RS13635	COG1492	cobalamin metabolic process
CFBP6625_RS13650	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6625_RS13655	COG3254	rhamnose metabolic process
CFBP6625_RS13660	COG0246	Mannitol dehydrogenase
CFBP6625_RS13665	COG1063	alcohol dehydrogenase
CFBP6625_RS13685	COG4214	carbohydrate transport
CFBP6625_RS13690	COG1129	ABC transporter
CFBP6625_RS13695	COG2186	Transcriptional regulator
CFBP6625_RS13700	COG2721	sulfolactate sulfo-lyase activity
CFBP6625_RS13705	COG0138	bifunctional purine biosynthesis protein purh
CFBP6625_RS13715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFBP6625_RS13720	COG0501	Belongs to the peptidase M48B family
CFBP6625_RS13740	COG0357	Ribosomal RNA small subunit methyltransferase G
CFBP6625_RS13745	COG0445	tRNA wobble uridine modification
CFBP6625_RS13750	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFBP6625_RS13755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFBP6625_RS13760	COG1981	membrane
CFBP6625_RS13765	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFBP6625_RS13770	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CFBP6625_RS13775	COG0424	maF-like protein
CFBP6625_RS13780	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP6625_RS13785	COG0237	dephospho-CoA kinase activity
CFBP6625_RS13795	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CFBP6625_RS13800	COG3030	protein affecting phage T7 exclusion by the F plasmid
CFBP6625_RS13810	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CFBP6625_RS13835	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFBP6625_RS13850	COG0135	phosphoribosylanthranilate isomerase activity
CFBP6625_RS13855	COG0133	tryptophan synthase activity
CFBP6625_RS13860	COG0159	tryptophan synthase activity
CFBP6625_RS13865	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFBP6625_RS13870	COG0285	dihydrofolate synthase activity
CFBP6625_RS13880	COG1074	ATP-dependent DNA helicase activity
CFBP6625_RS13890	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFBP6625_RS13895	COG0802	atpase or kinase
CFBP6625_RS13900	COG2205	protein histidine kinase activity
CFBP6625_RS13910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CFBP6625_RS13915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP6625_RS13920	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP6625_RS13920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFBP6625_RS13925	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFBP6625_RS13930	COG0642	Histidine kinase
CFBP6625_RS13935	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS13940	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CFBP6625_RS13950	COG1652	LysM domain
CFBP6625_RS13955	COG1072	(Pantothenic acid kinase))
CFBP6625_RS13960	COG0140	phosphoribosyl-ATP diphosphatase activity
CFBP6625_RS13965	COG0107	imidazoleglycerol-phosphate synthase activity
CFBP6625_RS13970	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFBP6625_RS13975	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFBP6625_RS13985	COG0131	Imidazoleglycerol-phosphate dehydratase
CFBP6625_RS13990	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFBP6625_RS13995	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFBP6625_RS14005	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFBP6625_RS14020	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CFBP6625_RS14030	COG1643	Atp-dependent helicase
CFBP6625_RS14075	COG0514	ATP-dependent DNA helicase (RecQ)
CFBP6625_RS14100	COG1072	(Pantothenic acid kinase))
CFBP6625_RS14110	COG1780	Probably involved in ribonucleotide reductase function
CFBP6625_RS14130	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFBP6625_RS14160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6625_RS14175	COG1185	polyribonucleotide nucleotidyltransferase activity
CFBP6625_RS14180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFBP6625_RS14185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFBP6625_RS14190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFBP6625_RS14200	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFBP6625_RS14200	COG3064	Membrane
CFBP6625_RS14215	COG0779	Required for maturation of 30S ribosomal subunits
CFBP6625_RS14220	COG2814	Major facilitator Superfamily
CFBP6625_RS14225	COG2951	lytic endotransglycosylase activity
CFBP6625_RS14230	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFBP6625_RS14240	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFBP6625_RS14245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFBP6625_RS14260	COG2816	NAD+ diphosphatase activity
CFBP6625_RS14265	COG0077	Prephenate dehydratase
CFBP6625_RS14265	COG1605	Chorismate mutase
CFBP6625_RS14270	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CFBP6625_RS14275	COG3474	cytochrome
CFBP6625_RS14285	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP6625_RS14290	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFBP6625_RS14300	COG1278	Cold shock
CFBP6625_RS14310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP6625_RS14320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP6625_RS14320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP6625_RS14330	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CFBP6625_RS14365	COG2900	Belongs to the SlyX family
CFBP6625_RS14375	COG0484	heat shock protein binding
CFBP6625_RS14380	COG0443	Heat shock 70 kDa protein
CFBP6625_RS14410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP6625_RS14415	COG1744	ABC transporter substrate-binding protein PnrA-like
CFBP6625_RS14420	COG3845	ABC transporter
CFBP6625_RS14425	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS14430	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS14435	COG0295	cytidine deaminase activity
CFBP6625_RS14440	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFBP6625_RS14445	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFBP6625_RS14450	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CFBP6625_RS14460	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFBP6625_RS14465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFBP6625_RS14470	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFBP6625_RS14480	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFBP6625_RS14485	COG1845	cytochrome c oxidase, subunit III
CFBP6625_RS14490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP6625_RS14500	COG0477	Major facilitator Superfamily
CFBP6625_RS14505	COG0067	glutamate synthase
CFBP6625_RS14505	COG0070	glutamate synthase
CFBP6625_RS14505	COG0069	glutamate synthase activity
CFBP6625_RS14510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CFBP6625_RS14525	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP6625_RS14535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP6625_RS14570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6625_RS14590	COG0848	biopolymer transport protein
CFBP6625_RS14600	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP6625_RS14625	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP6625_RS14630	COG3454	Phosphonate metabolism
CFBP6625_RS14635	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP6625_RS14640	COG3639	organic phosphonate transmembrane transporter activity
CFBP6625_RS14645	COG3639	organic phosphonate transmembrane transporter activity
CFBP6625_RS14655	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFBP6625_RS14665	COG4778	phosphonate C-P lyase system protein PhnL
CFBP6625_RS14670	COG4107	phosphonate C-P lyase system protein PhnK
CFBP6625_RS14675	COG3627	carbon phosphorus lyase activity
CFBP6625_RS14680	COG3626	phosphonate metabolism
CFBP6625_RS14685	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CFBP6625_RS14690	COG3624	Phosphonate C-P lyase system protein PhnG
CFBP6625_RS14695	COG2188	Transcriptional regulator
CFBP6625_RS14700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFBP6625_RS14705	COG0837	glucose binding
CFBP6625_RS14710	COG1803	Methylglyoxal synthase
CFBP6625_RS14715	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CFBP6625_RS14720	COG4166	transmembrane transport
CFBP6625_RS14725	COG4174	ABC transporter (Permease)
CFBP6625_RS14730	COG4239	(ABC) transporter, permease
CFBP6625_RS14735	COG4172	Belongs to the ABC transporter superfamily
CFBP6625_RS14740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS14745	COG0174	glutamine synthetase
CFBP6625_RS14750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS14755	COG3265	gluconokinase activity
CFBP6625_RS14760	COG1174	glycine betaine transport
CFBP6625_RS14765	COG1125	glycine betaine transport
CFBP6625_RS14770	COG1174	glycine betaine transport
CFBP6625_RS14775	COG1732	Glycine betaine
CFBP6625_RS14785	COG1959	2 iron, 2 sulfur cluster binding
CFBP6625_RS14790	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP6625_RS14800	COG4269	membrane
CFBP6625_RS14820	COG0697	spore germination
CFBP6625_RS14835	COG0791	NLP P60 protein
CFBP6625_RS14845	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFBP6625_RS14850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP6625_RS14885	COG4964	Belongs to the GSP D family
CFBP6625_RS14935	COG3422	double-strand break repair
CFBP6625_RS14940	COG3757	hydrolase, family 25
CFBP6625_RS14945	COG0697	spore germination
CFBP6625_RS14950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6625_RS14980	COG0481	GTPase activity
CFBP6625_RS14985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP6625_RS15015	COG1917	Cupin 2, conserved barrel domain protein
CFBP6625_RS15015	COG2169	Transcriptional regulator
CFBP6625_RS15020	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP6625_RS15045	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFBP6625_RS15050	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFBP6625_RS15055	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFBP6625_RS15065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFBP6625_RS15070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP6625_RS15070	COG0072	phenylalanine-tRNA ligase activity
CFBP6625_RS15075	COG0667	Aldo Keto reductase
CFBP6625_RS15095	COG4977	sequence-specific DNA binding
CFBP6625_RS15120	COG1570	exodeoxyribonuclease VII activity
CFBP6625_RS15125	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6625_RS15135	COG1846	Transcriptional regulator
CFBP6625_RS15140	COG0697	spore germination
CFBP6625_RS15145	COG2309	aminopeptidase activity
CFBP6625_RS15155	COG1393	Belongs to the ArsC family
CFBP6625_RS15170	COG0519	Catalyzes the synthesis of GMP from XMP
CFBP6625_RS15170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFBP6625_RS15185	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CFBP6625_RS15215	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CFBP6625_RS15225	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFBP6625_RS15235	COG1968	undecaprenyl-diphosphatase activity
CFBP6625_RS15260	COG0284	orotidine-5'-phosphate decarboxylase activity
CFBP6625_RS15270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFBP6625_RS15280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFBP6625_RS15285	COG0792	nuclease activity
CFBP6625_RS15300	COG1175	transmembrane transport
CFBP6625_RS15310	COG3842	ATPase activity
CFBP6625_RS15320	COG0189	ligase activity
CFBP6625_RS15330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFBP6625_RS15340	COG0756	dUTP diphosphatase activity
CFBP6625_RS15345	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFBP6625_RS15350	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFBP6625_RS15365	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFBP6625_RS15370	COG2226	methyltransferase
CFBP6625_RS15375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFBP6625_RS15380	COG1024	Enoyl-CoA hydratase
CFBP6625_RS15385	COG0268	Binds directly to 16S ribosomal RNA
CFBP6625_RS15400	COG4372	Transposase
CFBP6625_RS15405	COG3436	PFAM IS66 Orf2 family protein
CFBP6625_RS15430	COG4106	trans-aconitate 2-methyltransferase activity
CFBP6625_RS15435	COG1522	sequence-specific DNA binding
CFBP6625_RS15445	COG1522	sequence-specific DNA binding
CFBP6625_RS15455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6625_RS15460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP6625_RS15465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFBP6625_RS15470	COG2423	ornithine cyclodeaminase activity
CFBP6625_RS15475	COG0006	proline dipeptidase activity
CFBP6625_RS15480	COG3608	succinylglutamate desuccinylase aspartoacylase
CFBP6625_RS15485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6625_RS15490	COG0765	amino acid transport
CFBP6625_RS15495	COG0765	amino acid transport
CFBP6625_RS15500	COG1126	abc transporter atp-binding protein
CFBP6625_RS15505	COG0488	(ABC) transporter
CFBP6625_RS15510	COG2233	PERMEase
CFBP6625_RS15565	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS15570	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP6625_RS15580	COG3842	ATPase activity
CFBP6625_RS15600	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CFBP6625_RS15630	COG1653	transport
CFBP6625_RS15635	COG1175	transmembrane transport
CFBP6625_RS15640	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS15645	COG3842	ATPase activity
CFBP6625_RS15660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6625_RS15665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6625_RS15670	COG1116	anion transmembrane transporter activity
CFBP6625_RS15680	COG1609	Transcriptional regulator
CFBP6625_RS15695	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6625_RS15700	COG3842	ATPase activity
CFBP6625_RS15705	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS15710	COG1175	transmembrane transport
CFBP6625_RS15720	COG1309	transcriptional regulator
CFBP6625_RS15725	COG0673	inositol 2-dehydrogenase activity
CFBP6625_RS15740	COG0673	inositol 2-dehydrogenase activity
CFBP6625_RS15745	COG1278	Cold shock
CFBP6625_RS15755	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP6625_RS15785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP6625_RS15790	COG1136	(ABC) transporter
CFBP6625_RS15790	COG0577	efflux transmembrane transporter activity
CFBP6625_RS15795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS15830	COG1629	transport
CFBP6625_RS15835	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFBP6625_RS15850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6625_RS15855	COG3618	amidohydrolase
CFBP6625_RS15860	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6625_RS15865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6625_RS15870	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS15875	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CFBP6625_RS15880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6625_RS15885	COG2186	Transcriptional regulator
CFBP6625_RS15900	COG0667	Aldo Keto reductase
CFBP6625_RS15930	COG4977	sequence-specific DNA binding
CFBP6625_RS15935	COG2223	nitrite transmembrane transporter activity
CFBP6625_RS15940	COG0583	DNA-binding transcription factor activity
CFBP6625_RS15945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6625_RS15955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6625_RS15960	COG2084	Dehydrogenase
CFBP6625_RS15975	COG1609	Transcriptional regulator
CFBP6625_RS15980	COG1063	alcohol dehydrogenase
CFBP6625_RS15985	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS15995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6625_RS16000	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CFBP6625_RS16005	COG1175	transmembrane transport
CFBP6625_RS16010	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS16030	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS16035	COG1175	transmembrane transport
CFBP6625_RS16040	COG2182	Extracellular solute-binding protein
CFBP6625_RS16045	COG0626	cystathionine gamma-synthase activity
CFBP6625_RS16055	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFBP6625_RS16065	COG1121	(ABC) transporter
CFBP6625_RS16070	COG0523	cobalamin synthesis protein
CFBP6625_RS16085	COG0523	cobalamin synthesis protein
CFBP6625_RS16090	COG1653	transport
CFBP6625_RS16095	COG1175	transmembrane transport
CFBP6625_RS16100	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS16105	COG3842	ATPase activity
CFBP6625_RS16120	COG3047	cAMP biosynthetic process
CFBP6625_RS16145	COG0583	DNA-binding transcription factor activity
CFBP6625_RS16150	COG1879	ABC-type sugar transport system periplasmic component
CFBP6625_RS16155	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS16160	COG1129	ABC transporter
CFBP6625_RS16170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6625_RS16175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS16180	COG5002	protein histidine kinase activity
CFBP6625_RS16180	COG5001	Diguanylate cyclase
CFBP6625_RS16180	COG3447	MASE1 domain protein
CFBP6625_RS16185	COG3257	ureidoglycine aminohydrolase activity
CFBP6625_RS16195	COG5001	Diguanylate cyclase
CFBP6625_RS16200	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP6625_RS16210	COG0747	negative chemotaxis
CFBP6625_RS16215	COG0601	transmembrane transport
CFBP6625_RS16220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS16225	COG0444	Belongs to the ABC transporter superfamily
CFBP6625_RS16230	COG4608	Belongs to the ABC transporter superfamily
CFBP6625_RS16235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CFBP6625_RS16250	COG0346	lactoylglutathione lyase activity
CFBP6625_RS16260	COG0129	dihydroxy-acid dehydratase activity
CFBP6625_RS16265	COG1879	ABC-type sugar transport system periplasmic component
CFBP6625_RS16270	COG1129	ABC transporter
CFBP6625_RS16275	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS16280	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS16285	COG2186	Transcriptional regulator
CFBP6625_RS16305	COG0587	DNA-directed DNA polymerase activity
CFBP6625_RS16335	COG0673	inositol 2-dehydrogenase activity
CFBP6625_RS16345	COG3842	ATPase activity
CFBP6625_RS16350	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS16355	COG1175	transmembrane transport
CFBP6625_RS16360	COG1653	transport
CFBP6625_RS16370	COG0673	inositol 2-dehydrogenase activity
CFBP6625_RS16385	COG5001	Diguanylate cyclase
CFBP6625_RS16390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6625_RS16400	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CFBP6625_RS16405	COG2894	cell division
CFBP6625_RS16410	COG0850	regulation of cytokinetic process
CFBP6625_RS16415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP6625_RS16420	COG2186	Transcriptional regulator
CFBP6625_RS16425	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6625_RS16435	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6625_RS16440	COG1063	alcohol dehydrogenase
CFBP6625_RS16445	COG1312	Catalyzes the dehydration of D-mannonate
CFBP6625_RS16465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6625_RS16470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP6625_RS16470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6625_RS16475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS16490	COG0625	glutathione transferase activity
CFBP6625_RS16500	COG1921	L-seryl-tRNASec selenium transferase activity
CFBP6625_RS16515	COG3964	amidohydrolase
CFBP6625_RS16525	COG0601	transmembrane transport
CFBP6625_RS16535	COG0747	negative chemotaxis
CFBP6625_RS16540	COG0438	transferase activity, transferring glycosyl groups
CFBP6625_RS16580	COG4989	oxidoreductase activity
CFBP6625_RS16595	COG3842	ATPase activity
CFBP6625_RS16600	COG1653	transport
CFBP6625_RS16605	COG1175	transmembrane transport
CFBP6625_RS16610	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS16615	COG1501	Belongs to the glycosyl hydrolase 31 family
CFBP6625_RS16620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6625_RS16625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6625_RS16630	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CFBP6625_RS16635	COG0352	thiamine-phosphate diphosphorylase activity
CFBP6625_RS16640	COG0351	phosphomethylpyrimidine kinase
CFBP6625_RS16645	COG1522	sequence-specific DNA binding
CFBP6625_RS16650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP6625_RS16655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS16670	COG2204	response regulator
CFBP6625_RS16675	COG4191	Histidine kinase
CFBP6625_RS16680	COG1301	dicarboxylic acid transport
CFBP6625_RS16690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6625_RS16695	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS16705	COG1473	amidohydrolase
CFBP6625_RS16725	COG1215	transferase activity, transferring glycosyl groups
CFBP6625_RS16735	COG2942	2-epimerase
CFBP6625_RS16770	COG2197	response regulator
CFBP6625_RS16800	COG3307	-O-antigen
CFBP6625_RS16805	COG1596	polysaccharide export
CFBP6625_RS16815	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFBP6625_RS16825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6625_RS16830	COG0840	transmembrane signaling receptor activity
CFBP6625_RS16830	COG2972	Histidine kinase
CFBP6625_RS16835	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6625_RS16845	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS16855	COG2094	Belongs to the DNA glycosylase MPG family
CFBP6625_RS16870	COG1609	Transcriptional regulator
CFBP6625_RS16875	COG1653	transport
CFBP6625_RS16890	COG3842	ATPase activity
CFBP6625_RS16900	COG0673	inositol 2-dehydrogenase activity
CFBP6625_RS16905	COG0602	queuosine metabolic process
CFBP6625_RS16910	COG0720	synthase
CFBP6625_RS16915	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFBP6625_RS16920	COG0673	inositol 2-dehydrogenase activity
CFBP6625_RS16935	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS16940	COG1175	transmembrane transport
CFBP6625_RS16970	COG0583	DNA-binding transcription factor activity
CFBP6625_RS16975	COG0280	phosphate acetyltransferase
CFBP6625_RS16975	COG0281	malic enzyme
CFBP6625_RS16990	COG0765	amino acid transport
CFBP6625_RS16995	COG1126	abc transporter atp-binding protein
CFBP6625_RS17000	COG2079	MmgE PrpD family protein
CFBP6625_RS17005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS17015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS17040	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP6625_RS17045	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFBP6625_RS17050	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS17055	COG1129	ABC transporter
CFBP6625_RS17070	COG1473	amidohydrolase
CFBP6625_RS17075	COG0747	negative chemotaxis
CFBP6625_RS17085	COG4172	Belongs to the ABC transporter superfamily
CFBP6625_RS17090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS17095	COG0601	transmembrane transport
CFBP6625_RS17100	COG0583	DNA-binding transcription factor activity
CFBP6625_RS17105	COG1446	asparaginase
CFBP6625_RS17120	COG0747	negative chemotaxis
CFBP6625_RS17140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS17145	COG0601	transmembrane transport
CFBP6625_RS17150	COG2197	response regulator
CFBP6625_RS17155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP6625_RS17165	COG0673	inositol 2-dehydrogenase activity
CFBP6625_RS17170	COG0673	inositol 2-dehydrogenase activity
CFBP6625_RS17190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS17195	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP6625_RS17215	COG1595	DNA-templated transcription, initiation
CFBP6625_RS17220	COG1120	ATPase activity
CFBP6625_RS17225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6625_RS17240	COG2226	methyltransferase
CFBP6625_RS17250	COG1120	ATPase activity
CFBP6625_RS17255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6625_RS17275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP6625_RS17285	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS17290	COG0473	3-isopropylmalate dehydrogenase activity
CFBP6625_RS17295	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS17300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS17330	COG0601	transmembrane transport
CFBP6625_RS17335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS17340	COG4172	Belongs to the ABC transporter superfamily
CFBP6625_RS17345	COG1522	sequence-specific DNA binding
CFBP6625_RS17350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS17360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6625_RS17365	COG1126	abc transporter atp-binding protein
CFBP6625_RS17375	COG1473	amidohydrolase
CFBP6625_RS17380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS17385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS17390	COG1959	2 iron, 2 sulfur cluster binding
CFBP6625_RS17400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP6625_RS17405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS17435	COG1960	acyl-CoA dehydrogenase activity
CFBP6625_RS17470	COG0667	Aldo Keto reductase
CFBP6625_RS17480	COG0583	DNA-binding transcription factor activity
CFBP6625_RS17505	COG0747	negative chemotaxis
CFBP6625_RS17510	COG1473	amidohydrolase
CFBP6625_RS17515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS17530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS17535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS17540	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6625_RS17555	COG4608	Belongs to the ABC transporter superfamily
CFBP6625_RS17560	COG0444	Belongs to the ABC transporter superfamily
CFBP6625_RS17570	COG0601	transmembrane transport
CFBP6625_RS17580	COG2186	Transcriptional regulator
CFBP6625_RS17595	COG0300	oxidoreductase activity
CFBP6625_RS17605	COG3453	Protein conserved in bacteria
CFBP6625_RS17605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6625_RS17610	COG0640	Transcriptional regulator
CFBP6625_RS17620	COG2391	methyltransferase activity
CFBP6625_RS17625	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFBP6625_RS17645	COG0022	dehydrogenase e1 component
CFBP6625_RS17655	COG1960	acyl-CoA dehydrogenase activity
CFBP6625_RS17660	COG0183	Belongs to the thiolase family
CFBP6625_RS17670	COG1960	acyl-CoA dehydrogenase activity
CFBP6625_RS17675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP6625_RS17695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFBP6625_RS17700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CFBP6625_RS17705	COG4952	isomerase
CFBP6625_RS17710	COG3347	Dehydrogenase
CFBP6625_RS17710	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS17715	COG1349	DNA-binding transcription factor activity
CFBP6625_RS17730	COG1129	ABC transporter
CFBP6625_RS17735	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS17740	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS17745	COG3254	rhamnose metabolic process
CFBP6625_RS17760	COG2264	protein methyltransferase activity
CFBP6625_RS17765	COG5001	Diguanylate cyclase
CFBP6625_RS17780	COG4335	DNA alkylation repair
CFBP6625_RS17785	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP6625_RS17790	COG4208	sulfate ABC transporter
CFBP6625_RS17800	COG4150	thiosulfate binding
CFBP6625_RS17805	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CFBP6625_RS17820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP6625_RS17830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP6625_RS17840	COG1040	competence protein
CFBP6625_RS17845	COG2226	methyltransferase
CFBP6625_RS17860	COG0494	nUDIX hydrolase
CFBP6625_RS17870	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFBP6625_RS17875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFBP6625_RS17880	COG0653	protein targeting
CFBP6625_RS17885	COG0697	spore germination
CFBP6625_RS18030	COG0740	serine-type endopeptidase activity
CFBP6625_RS18165	COG3916	Acyl-homoserine-lactone synthase
CFBP6625_RS18210	COG0583	DNA-binding transcription factor activity
CFBP6625_RS18220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS18230	COG4608	Belongs to the ABC transporter superfamily
CFBP6625_RS18240	COG0747	negative chemotaxis
CFBP6625_RS18280	COG2244	polysaccharide biosynthetic process
CFBP6625_RS18295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP6625_RS18305	COG0489	protein tyrosine kinase activity
CFBP6625_RS18305	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP6625_RS18330	COG0438	transferase activity, transferring glycosyl groups
CFBP6625_RS18345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFBP6625_RS18350	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CFBP6625_RS18350	COG2273	Hydrolase Family 16
CFBP6625_RS18365	COG3842	ATPase activity
CFBP6625_RS18370	COG3833	ABC-type maltose transport systems, permease component
CFBP6625_RS18425	COG1396	sequence-specific DNA binding
CFBP6625_RS18435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFBP6625_RS18440	COG1129	ABC transporter
CFBP6625_RS18445	COG4214	carbohydrate transport
CFBP6625_RS18450	COG4213	ABC transporter substrate-binding protein
CFBP6625_RS18465	COG0346	lactoylglutathione lyase activity
CFBP6625_RS18470	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFBP6625_RS18470	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFBP6625_RS18475	COG4770	biotin carboxylase activity
CFBP6625_RS18485	COG0625	glutathione transferase activity
CFBP6625_RS18490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP6625_RS18495	COG1396	sequence-specific DNA binding
CFBP6625_RS18495	COG3800	Transcriptional regulator
CFBP6625_RS18505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP6625_RS18515	COG0300	oxidoreductase activity
CFBP6625_RS18525	COG2096	Adenosyltransferase
CFBP6625_RS18535	COG2086	electron transfer activity
CFBP6625_RS18545	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP6625_RS18550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFBP6625_RS18555	COG0165	Argininosuccinate lyase
CFBP6625_RS18590	COG2884	Cell division ATP-binding protein ftsE
CFBP6625_RS18610	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CFBP6625_RS18620	COG0287	Prephenate dehydrogenase
CFBP6625_RS18625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP6625_RS18630	COG2226	methyltransferase
CFBP6625_RS18635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP6625_RS18650	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFBP6625_RS18655	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFBP6625_RS18690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFBP6625_RS18695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFBP6625_RS18710	COG4974	Belongs to the 'phage' integrase family
CFBP6625_RS18715	COG0825	malonyl-CoA metabolic process
CFBP6625_RS18720	COG3034	peptidoglycan biosynthetic process
CFBP6625_RS18725	COG0425	Belongs to the sulfur carrier protein TusA family
CFBP6625_RS18725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFBP6625_RS18735	COG0523	cobalamin synthesis protein
CFBP6625_RS18740	COG1686	Belongs to the peptidase S11 family
CFBP6625_RS18745	COG1473	amidohydrolase
CFBP6625_RS18765	COG4953	penicillin-binding protein 1C
CFBP6625_RS18770	COG2373	Large extracellular alpha-helical protein
CFBP6625_RS18775	COG2835	tetraacyldisaccharide 4'-kinase activity
CFBP6625_RS18785	COG3118	belongs to the thioredoxin family
CFBP6625_RS18815	COG0482	sulfurtransferase activity
CFBP6625_RS18830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP6625_RS18845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP6625_RS18850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP6625_RS18855	COG0037	tRNA processing
CFBP6625_RS18865	COG2885	chlorophyll binding
CFBP6625_RS18870	COG0823	Involved in the tonB-independent uptake of proteins
CFBP6625_RS18890	COG0824	Thioesterase
CFBP6625_RS18900	COG0494	nUDIX hydrolase
CFBP6625_RS18910	COG1408	metallophosphoesterase
CFBP6625_RS18915	COG2255	four-way junction helicase activity
CFBP6625_RS18930	COG0632	four-way junction helicase activity
CFBP6625_RS18935	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CFBP6625_RS18940	COG2972	Histidine kinase
CFBP6625_RS18940	COG0840	transmembrane signaling receptor activity
CFBP6625_RS18945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS18950	COG0217	transcriptional regulatory protein
CFBP6625_RS18965	COG1692	metallophosphoesterase
CFBP6625_RS18975	COG1253	flavin adenine dinucleotide binding
CFBP6625_RS19025	COG0126	phosphoglycerate kinase activity
CFBP6625_RS19030	COG3588	fructose-bisphosphate aldolase
CFBP6625_RS19050	COG0254	rRNA binding
CFBP6625_RS19055	COG1132	(ABC) transporter
CFBP6625_RS19080	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6625_RS19110	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFBP6625_RS19115	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFBP6625_RS19120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFBP6625_RS19125	COG0457	Tetratricopeptide repeat
CFBP6625_RS19130	COG3750	Belongs to the UPF0335 family
CFBP6625_RS19150	COG0469	pyruvate kinase activity
CFBP6625_RS19155	COG3108	Peptidase M15
CFBP6625_RS19160	COG2204	response regulator
CFBP6625_RS19165	COG1164	Oligoendopeptidase f
CFBP6625_RS19170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP6625_RS19180	COG5310	Homospermidine synthase
CFBP6625_RS19190	COG0737	Belongs to the 5'-nucleotidase family
CFBP6625_RS19195	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CFBP6625_RS19200	COG0330	HflC and HflK could
CFBP6625_RS19230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP6625_RS19235	COG2951	lytic endotransglycosylase activity
CFBP6625_RS19260	COG0067	glutamate synthase
CFBP6625_RS19260	COG0069	glutamate synthase activity
CFBP6625_RS19260	COG0070	glutamate synthase
CFBP6625_RS19275	COG2205	protein histidine kinase activity
CFBP6625_RS19280	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CFBP6625_RS19285	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CFBP6625_RS19290	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CFBP6625_RS19300	COG0252	asparaginase activity
CFBP6625_RS19310	COG1027	Aspartate ammonia-lyase
CFBP6625_RS19315	COG2186	Transcriptional regulator
CFBP6625_RS19330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS19335	COG1309	transcriptional regulator
CFBP6625_RS19350	COG2086	electron transfer activity
CFBP6625_RS19355	COG1126	abc transporter atp-binding protein
CFBP6625_RS19360	COG0765	amino acid transport
CFBP6625_RS19375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6625_RS19395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP6625_RS19400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP6625_RS19405	COG0583	DNA-binding transcription factor activity
CFBP6625_RS19445	COG2307	Protein conserved in bacteria
CFBP6625_RS19445	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP6625_RS19460	COG0488	(ABC) transporter
CFBP6625_RS19465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6625_RS19470	COG1304	FMN binding
CFBP6625_RS19500	COG1063	alcohol dehydrogenase
CFBP6625_RS19505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP6625_RS19510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6625_RS19520	COG0765	amino acid transport
CFBP6625_RS19525	COG0765	amino acid transport
CFBP6625_RS19530	COG4221	oxidoreductase activity
CFBP6625_RS19535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6625_RS19540	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS19545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6625_RS19560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP6625_RS19575	COG0697	spore germination
CFBP6625_RS19580	COG0697	spore germination
CFBP6625_RS19585	COG0511	ligase activity, forming carbon-carbon bonds
CFBP6625_RS19590	COG0439	Biotin carboxylase
CFBP6625_RS19600	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP6625_RS19605	COG1984	allophanate hydrolase subunit 2
CFBP6625_RS19610	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP6625_RS19615	COG3842	ATPase activity
CFBP6625_RS19625	COG1177	transmembrane transport
CFBP6625_RS19635	COG0436	Aminotransferase
CFBP6625_RS19650	COG1070	Carbohydrate kinase
CFBP6625_RS19655	COG1830	Aldolase
CFBP6625_RS19660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFBP6625_RS19665	COG0667	Aldo Keto reductase
CFBP6625_RS19675	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS19680	COG1129	ABC transporter
CFBP6625_RS19685	COG1879	ABC-type sugar transport system periplasmic component
CFBP6625_RS19715	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6625_RS19730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP6625_RS19745	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS19760	COG3842	ATPase activity
CFBP6625_RS19775	COG1648	precorrin-2 dehydrogenase activity
CFBP6625_RS19775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP6625_RS19780	COG0243	molybdopterin cofactor binding
CFBP6625_RS19790	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFBP6625_RS19795	COG1116	anion transmembrane transporter activity
CFBP6625_RS19800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6625_RS19805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6625_RS19815	COG3707	response regulator
CFBP6625_RS19820	COG1802	Transcriptional regulator
CFBP6625_RS19825	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP6625_RS19830	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP6625_RS19835	COG4336	lyase activity
CFBP6625_RS19840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP6625_RS19845	COG4770	biotin carboxylase activity
CFBP6625_RS19850	COG0366	Alpha amylase catalytic
CFBP6625_RS19860	COG4771	TonB-dependent receptor
CFBP6625_RS19865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFBP6625_RS19885	COG1414	Transcriptional regulator
CFBP6625_RS19890	COG1475	DNA binding
CFBP6625_RS19895	COG1192	Involved in chromosome partitioning
CFBP6625_RS19925	COG0596	Alpha beta hydrolase
CFBP6625_RS19930	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFBP6625_RS19940	COG2986	histidine ammonia-lyase
CFBP6625_RS19945	COG1228	amidohydrolase
CFBP6625_RS20025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFBP6625_RS20030	COG0270	DNA (cytosine-5-)-methyltransferase activity
CFBP6625_RS20065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CFBP6625_RS20080	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFBP6625_RS20090	COG2986	histidine ammonia-lyase
CFBP6625_RS20095	COG4172	Belongs to the ABC transporter superfamily
CFBP6625_RS20100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS20105	COG0601	transmembrane transport
CFBP6625_RS20110	COG4166	transmembrane transport
CFBP6625_RS20140	COG2205	protein histidine kinase activity
CFBP6625_RS20155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFBP6625_RS20160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP6625_RS20210	COG0183	Belongs to the thiolase family
CFBP6625_RS20215	COG3396	Phenylacetate-CoA oxygenase
CFBP6625_RS20220	COG3460	Phenylacetate-CoA oxygenase
CFBP6625_RS20225	COG3396	Phenylacetate-CoA oxygenase
CFBP6625_RS20230	COG2151	metal-sulfur cluster biosynthetic enzyme
CFBP6625_RS20235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFBP6625_RS20245	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS20245	COG2030	dehydratase
CFBP6625_RS20250	COG1309	transcriptional regulator
CFBP6625_RS20260	COG2050	protein possibly involved in aromatic compounds catabolism
CFBP6625_RS20265	COG1024	Enoyl-CoA hydratase
CFBP6625_RS20270	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS20280	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS20325	COG1175	transmembrane transport
CFBP6625_RS20330	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS20335	COG3842	ATPase activity
CFBP6625_RS20350	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP6625_RS20360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6625_RS20370	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS20380	COG1653	transport
CFBP6625_RS20385	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS20390	COG4209	transmembrane transport
CFBP6625_RS20395	COG3842	ATPase activity
CFBP6625_RS20400	COG1802	Transcriptional regulator
CFBP6625_RS20405	COG0583	DNA-binding transcription factor activity
CFBP6625_RS20410	COG0346	lactoylglutathione lyase activity
CFBP6625_RS20425	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CFBP6625_RS20450	COG0356	it plays a direct role in the translocation of protons across the membrane
CFBP6625_RS20460	COG0387	Pfam Sodium calcium exchanger
CFBP6625_RS20465	COG2212	antiporter activity
CFBP6625_RS20470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP6625_RS20475	COG0583	DNA-binding transcription factor activity
CFBP6625_RS20480	COG0477	Major facilitator Superfamily
CFBP6625_RS20525	COG0456	acetyltransferase
CFBP6625_RS20530	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CFBP6625_RS20535	COG0156	8-amino-7-oxononanoate synthase activity
CFBP6625_RS20540	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CFBP6625_RS20545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP6625_RS20550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFBP6625_RS20570	COG0010	Belongs to the arginase family
CFBP6625_RS20580	COG0697	spore germination
CFBP6625_RS20585	COG0673	inositol 2-dehydrogenase activity
CFBP6625_RS20610	COG0477	Major facilitator Superfamily
CFBP6625_RS20625	COG2194	sulfuric ester hydrolase activity
CFBP6625_RS20635	COG0583	DNA-binding transcription factor activity
CFBP6625_RS20640	COG4774	siderophore transport
CFBP6625_RS20655	COG1120	ATPase activity
CFBP6625_RS20665	COG3474	cytochrome
CFBP6625_RS20670	COG2137	regulation of response to DNA damage stimulus
CFBP6625_RS20675	COG3386	PFAM SMP-30 Gluconolaconase
CFBP6625_RS20685	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS20690	COG1129	ABC transporter
CFBP6625_RS20695	COG1879	ABC-type sugar transport system periplasmic component
CFBP6625_RS20705	COG4585	Histidine kinase
CFBP6625_RS20710	COG2197	response regulator
CFBP6625_RS20720	COG2133	pyrroloquinoline quinone binding
CFBP6625_RS20730	COG0500	methyltransferase
CFBP6625_RS20735	COG0564	pseudouridine synthase activity
CFBP6625_RS20755	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP6625_RS20770	COG0784	Response regulator, receiver
CFBP6625_RS20770	COG4191	Histidine kinase
CFBP6625_RS20780	COG0489	protein tyrosine kinase activity
CFBP6625_RS20780	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP6625_RS20785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP6625_RS20790	COG1215	transferase activity, transferring glycosyl groups
CFBP6625_RS20795	COG1215	transferase activity, transferring glycosyl groups
CFBP6625_RS20800	COG1215	transferase activity, transferring glycosyl groups
CFBP6625_RS20805	COG0438	transferase activity, transferring glycosyl groups
CFBP6625_RS20810	COG2273	Hydrolase Family 16
CFBP6625_RS20815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP6625_RS20820	COG2244	polysaccharide biosynthetic process
CFBP6625_RS20825	COG0463	Glycosyl transferase, family 2
CFBP6625_RS20830	COG2327	Polysaccharide pyruvyl transferase
CFBP6625_RS20835	COG1215	transferase activity, transferring glycosyl groups
CFBP6625_RS20855	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP6625_RS20865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS20880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP6625_RS20880	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP6625_RS20905	COG1523	belongs to the glycosyl hydrolase 13 family
CFBP6625_RS20910	COG0033	Phosphoglucomutase
CFBP6625_RS20915	COG0297	glycogen (starch) synthase activity
CFBP6625_RS20920	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CFBP6625_RS20925	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFBP6625_RS20930	COG0058	SHG alpha-glucan phosphorylase activity
CFBP6625_RS20945	COG1794	racemase activity, acting on amino acids and derivatives
CFBP6625_RS20950	COG1522	sequence-specific DNA binding
CFBP6625_RS20960	COG2084	Dehydrogenase
CFBP6625_RS20965	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS20970	COG1063	alcohol dehydrogenase
CFBP6625_RS20980	COG4988	ABC transporter
CFBP6625_RS20985	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CFBP6625_RS20995	COG1294	oxidase, subunit
CFBP6625_RS21025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CFBP6625_RS21030	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFBP6625_RS21055	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CFBP6625_RS21065	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CFBP6625_RS21105	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CFBP6625_RS21110	COG0539	negative regulation of cytoplasmic translation
CFBP6625_RS21140	COG4221	oxidoreductase activity
CFBP6625_RS21150	COG0006	proline dipeptidase activity
CFBP6625_RS21155	COG0747	negative chemotaxis
CFBP6625_RS21160	COG0601	transmembrane transport
CFBP6625_RS21165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS21170	COG0444	Belongs to the ABC transporter superfamily
CFBP6625_RS21175	COG4608	Belongs to the ABC transporter superfamily
CFBP6625_RS21180	COG0246	Mannitol dehydrogenase
CFBP6625_RS21195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS21240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP6625_RS21245	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS21255	COG4993	Dehydrogenase
CFBP6625_RS21260	COG3685	Protein conserved in bacteria
CFBP6625_RS21265	COG1285	pathogenesis
CFBP6625_RS21270	COG0562	UDP-galactopyranose mutase
CFBP6625_RS21290	COG0693	protein deglycase activity
CFBP6625_RS21315	COG0189	ligase activity
CFBP6625_RS21320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP6625_RS21325	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFBP6625_RS21335	COG0435	Glutathione S-transferase
CFBP6625_RS21340	COG0583	DNA-binding transcription factor activity
CFBP6625_RS21350	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS21360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6625_RS21365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6625_RS21370	COG1116	anion transmembrane transporter activity
CFBP6625_RS21385	COG1522	sequence-specific DNA binding
CFBP6625_RS21400	COG0784	Response regulator, receiver
CFBP6625_RS21410	COG3920	Histidine kinase
CFBP6625_RS21420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFBP6625_RS21435	COG0019	diaminopimelate decarboxylase activity
CFBP6625_RS21445	COG1309	transcriptional regulator
CFBP6625_RS21465	COG0527	aspartate kinase activity
CFBP6625_RS21475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFBP6625_RS21480	COG2890	protein-(glutamine-N5) methyltransferase activity
CFBP6625_RS21490	COG0542	response to heat
CFBP6625_RS21495	COG0741	lytic transglycosylase activity
CFBP6625_RS21495	COG1196	nuclear chromosome segregation
CFBP6625_RS21495	COG0739	heme binding
CFBP6625_RS21580	COG0582	viral genome integration into host DNA
CFBP6625_RS21620	COG2860	membrane
CFBP6625_RS21640	COG2200	EAL domain
CFBP6625_RS21650	COG2271	Major facilitator Superfamily
CFBP6625_RS21685	COG3177	Filamentation induced by cAMP protein fic
CFBP6625_RS21705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS21710	COG0577	efflux transmembrane transporter activity
CFBP6625_RS21710	COG1136	(ABC) transporter
CFBP6625_RS21725	COG0405	Gamma-glutamyltransferase
CFBP6625_RS21735	COG0534	Mate efflux family protein
CFBP6625_RS21745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS21750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP6625_RS21775	COG0583	DNA-binding transcription factor activity
CFBP6625_RS21785	COG1120	ATPase activity
CFBP6625_RS21795	COG4774	siderophore transport
CFBP6625_RS21820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP6625_RS21825	COG1956	GAF domain-containing protein
CFBP6625_RS21840	COG3210	domain, Protein
CFBP6625_RS21845	COG2831	hemolysin activation secretion protein
CFBP6625_RS21870	COG2267	carboxylic ester hydrolase activity
CFBP6625_RS21880	COG1049	propionate catabolic process, 2-methylcitrate cycle
CFBP6625_RS21890	COG0367	asparagine synthase
CFBP6625_RS21900	COG0318	PFAM AMP-dependent synthetase and ligase
CFBP6625_RS21905	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CFBP6625_RS21930	COG4702	Belongs to the UPF0303 family
CFBP6625_RS21950	COG1024	Enoyl-CoA hydratase
CFBP6625_RS21955	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS21960	COG1653	transport
CFBP6625_RS21965	COG1175	transmembrane transport
CFBP6625_RS21970	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS21975	COG3842	ATPase activity
CFBP6625_RS21990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CFBP6625_RS21995	COG2376	Dihydroxyacetone kinase
CFBP6625_RS22005	COG1309	transcriptional regulator
CFBP6625_RS22020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6625_RS22025	COG1957	nucleoside hydrolase
CFBP6625_RS22035	COG0601	transmembrane transport
CFBP6625_RS22040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS22045	COG4172	Belongs to the ABC transporter superfamily
CFBP6625_RS22055	COG1063	alcohol dehydrogenase
CFBP6625_RS22065	COG1879	ABC-type sugar transport system periplasmic component
CFBP6625_RS22075	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS22095	COG0477	Major facilitator Superfamily
CFBP6625_RS22105	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6625_RS22130	COG1178	ABC-type Fe3 transport system permease component
CFBP6625_RS22135	COG3842	ATPase activity
CFBP6625_RS22155	COG0483	inositol monophosphate 1-phosphatase activity
CFBP6625_RS22165	COG1253	flavin adenine dinucleotide binding
CFBP6625_RS22180	COG3842	ATPase activity
CFBP6625_RS22185	COG1177	transmembrane transport
CFBP6625_RS22210	COG0668	transmembrane transport
CFBP6625_RS22230	COG1879	ABC-type sugar transport system periplasmic component
CFBP6625_RS22235	COG1129	ABC transporter
CFBP6625_RS22240	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS22245	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS22250	COG1609	Transcriptional regulator
CFBP6625_RS22260	COG0673	inositol 2-dehydrogenase activity
CFBP6625_RS22285	COG3189	MarR family transcriptional regulator
CFBP6625_RS22290	COG0583	DNA-binding transcription factor activity
CFBP6625_RS22300	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP6625_RS22305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS22320	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS22325	COG1535	isochorismatase
CFBP6625_RS22325	COG3433	isochorismatase activity
CFBP6625_RS22330	COG1021	2,3-dihydroxybenzoate-AMP ligase
CFBP6625_RS22335	COG1169	isochorismate synthase
CFBP6625_RS22345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFBP6625_RS22345	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CFBP6625_RS22350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFBP6625_RS22360	COG2375	cellular response to nickel ion
CFBP6625_RS22370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6625_RS22375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6625_RS22385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP6625_RS22395	COG1629	transport
CFBP6625_RS22395	COG4774	siderophore transport
CFBP6625_RS22400	COG1960	acyl-CoA dehydrogenase activity
CFBP6625_RS22405	COG0583	DNA-binding transcription factor activity
CFBP6625_RS22410	COG1609	Transcriptional regulator
CFBP6625_RS22420	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP6625_RS22430	COG3842	ATPase activity
CFBP6625_RS22440	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP6625_RS22450	COG1473	amidohydrolase
CFBP6625_RS22465	COG0747	negative chemotaxis
CFBP6625_RS22470	COG0601	transmembrane transport
CFBP6625_RS22475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS22480	COG0444	Belongs to the ABC transporter superfamily
CFBP6625_RS22485	COG4608	Belongs to the ABC transporter superfamily
CFBP6625_RS22490	COG0583	DNA-binding transcription factor activity
CFBP6625_RS22495	COG0747	negative chemotaxis
CFBP6625_RS22505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS22510	COG0154	amidase activity
CFBP6625_RS22515	COG0693	protein deglycase activity
CFBP6625_RS22530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS22535	COG0601	transmembrane transport
CFBP6625_RS22545	COG1473	amidohydrolase
CFBP6625_RS22550	COG4172	Belongs to the ABC transporter superfamily
CFBP6625_RS22555	COG2390	Transcriptional regulator
CFBP6625_RS22565	COG1175	transmembrane transport
CFBP6625_RS22570	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS22620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP6625_RS22630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFBP6625_RS22635	COG1414	Transcriptional regulator
CFBP6625_RS22640	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS22650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP6625_RS22655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP6625_RS22660	COG1121	(ABC) transporter
CFBP6625_RS22665	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFBP6625_RS22675	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFBP6625_RS22680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP6625_RS22685	COG0471	metal ion transport
CFBP6625_RS22685	COG3273	potassium ion transport
CFBP6625_RS22690	COG2827	Endonuclease containing a URI domain
CFBP6625_RS22695	COG1253	flavin adenine dinucleotide binding
CFBP6625_RS22700	COG1309	transcriptional regulator
CFBP6625_RS22715	COG1609	Transcriptional regulator
CFBP6625_RS22720	COG1070	Carbohydrate kinase
CFBP6625_RS22730	COG2115	Belongs to the xylose isomerase family
CFBP6625_RS22740	COG0778	Nitroreductase
CFBP6625_RS22745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFBP6625_RS22750	COG2011	ABC-type metal ion transport system permease component
CFBP6625_RS22760	COG5001	Diguanylate cyclase
CFBP6625_RS22760	COG3300	MHYT domain
CFBP6625_RS22765	COG1054	Belongs to the UPF0176 family
CFBP6625_RS22775	COG2954	triphosphatase activity
CFBP6625_RS22780	COG0800	Aldolase
CFBP6625_RS22805	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CFBP6625_RS22840	COG0523	cobalamin synthesis protein
CFBP6625_RS22850	COG1846	Transcriptional regulator
CFBP6625_RS22855	COG1609	Transcriptional regulator
CFBP6625_RS22865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6625_RS22880	COG3718	enzyme involved in inositol metabolism
CFBP6625_RS22890	COG3962	Belongs to the TPP enzyme family
CFBP6625_RS22895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6625_RS22940	COG0683	leucine binding
CFBP6625_RS22955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS22965	COG0747	negative chemotaxis
CFBP6625_RS22985	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CFBP6625_RS22985	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6625_RS22995	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP6625_RS23000	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP6625_RS23005	COG1126	abc transporter atp-binding protein
CFBP6625_RS23010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6625_RS23015	COG0765	amino acid transport
CFBP6625_RS23020	COG0765	amino acid transport
CFBP6625_RS23030	COG3485	protocatechuate 3,4-dioxygenase
CFBP6625_RS23035	COG3485	protocatechuate 3,4-dioxygenase
CFBP6625_RS23040	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFBP6625_RS23045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFBP6625_RS23050	COG0583	DNA-binding transcription factor activity
CFBP6625_RS23065	COG1414	Transcriptional regulator
CFBP6625_RS23075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFBP6625_RS23080	COG0183	Belongs to the thiolase family
CFBP6625_RS23100	COG1082	Xylose isomerase domain protein TIM barrel
CFBP6625_RS23105	COG0673	inositol 2-dehydrogenase activity
CFBP6625_RS23115	COG1609	Transcriptional regulator
CFBP6625_RS23120	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS23125	COG1175	transmembrane transport
CFBP6625_RS23130	COG3842	ATPase activity
CFBP6625_RS23140	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFBP6625_RS23155	COG1846	Transcriptional regulator
CFBP6625_RS23155	COG1940	carbohydrate kinase activity
CFBP6625_RS23165	COG3842	ATPase activity
CFBP6625_RS23170	COG1177	transmembrane transport
CFBP6625_RS23185	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFBP6625_RS23215	COG0385	Bile acid
CFBP6625_RS23220	COG0667	Aldo Keto reductase
CFBP6625_RS23225	COG0583	DNA-binding transcription factor activity
CFBP6625_RS23235	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFBP6625_RS23245	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS23255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6625_RS23270	COG1132	(ABC) transporter
CFBP6625_RS23275	COG0438	transferase activity, transferring glycosyl groups
CFBP6625_RS23285	COG0859	PFAM glycosyl transferase family 9
CFBP6625_RS23295	COG2942	2-epimerase
CFBP6625_RS23310	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CFBP6625_RS23310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CFBP6625_RS23320	COG0463	Glycosyl transferase, family 2
CFBP6625_RS23330	COG3958	Transketolase
CFBP6625_RS23335	COG3959	Transketolase, thiamine diphosphate binding domain
CFBP6625_RS23360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFBP6625_RS23375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6625_RS23380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP6625_RS23385	COG1120	ATPase activity
CFBP6625_RS23395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP6625_RS23410	COG1609	Transcriptional regulator
CFBP6625_RS23415	COG1233	COG1233 Phytoene dehydrogenase and related
CFBP6625_RS23430	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS23435	COG3842	ATPase activity
CFBP6625_RS23440	COG4608	Belongs to the ABC transporter superfamily
CFBP6625_RS23445	COG0444	Belongs to the ABC transporter superfamily
CFBP6625_RS23450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS23455	COG0601	transmembrane transport
CFBP6625_RS23460	COG2186	Transcriptional regulator
CFBP6625_RS23480	COG3300	MHYT domain
CFBP6625_RS23480	COG5001	Diguanylate cyclase
CFBP6625_RS23490	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP6625_RS23500	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP6625_RS23505	COG0306	phosphate transporter
CFBP6625_RS23510	COG1392	Phosphate transport regulator
CFBP6625_RS23525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS23530	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS23535	COG5002	protein histidine kinase activity
CFBP6625_RS23555	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CFBP6625_RS23595	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS23610	COG3119	arylsulfatase activity
CFBP6625_RS23615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6625_RS23620	COG3842	ATPase activity
CFBP6625_RS23625	COG0165	Argininosuccinate lyase
CFBP6625_RS23630	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS23635	COG1175	transmembrane transport
CFBP6625_RS23640	COG2182	Extracellular solute-binding protein
CFBP6625_RS23645	COG1940	carbohydrate kinase activity
CFBP6625_RS23670	COG1486	melibiose metabolic process
CFBP6625_RS23675	COG0747	negative chemotaxis
CFBP6625_RS23680	COG0601	transmembrane transport
CFBP6625_RS23685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS23690	COG4172	Belongs to the ABC transporter superfamily
CFBP6625_RS23695	COG1486	melibiose metabolic process
CFBP6625_RS23700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS23705	COG0842	Transport permease protein
CFBP6625_RS23705	COG1129	ABC transporter
CFBP6625_RS23710	COG0842	Transport permease protein
CFBP6625_RS23725	COG0784	Response regulator, receiver
CFBP6625_RS23730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP6625_RS23740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6625_RS23745	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP6625_RS23760	COG0765	amino acid transport
CFBP6625_RS23770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS23780	COG3938	Belongs to the proline racemase family
CFBP6625_RS23795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP6625_RS23800	COG0765	amino acid transport
CFBP6625_RS23805	COG0765	amino acid transport
CFBP6625_RS23815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP6625_RS23830	COG0402	S-adenosylhomocysteine deaminase activity
CFBP6625_RS23835	COG4166	transmembrane transport
CFBP6625_RS23840	COG0601	transmembrane transport
CFBP6625_RS23845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS23855	COG0402	S-adenosylhomocysteine deaminase activity
CFBP6625_RS23860	COG0444	Belongs to the ABC transporter superfamily
CFBP6625_RS23865	COG4608	Belongs to the ABC transporter superfamily
CFBP6625_RS23870	COG1802	Transcriptional regulator
CFBP6625_RS23875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP6625_RS23895	COG3237	CsbD-like
CFBP6625_RS23900	COG2197	response regulator
CFBP6625_RS23905	COG2186	Transcriptional regulator
CFBP6625_RS23910	COG0747	negative chemotaxis
CFBP6625_RS23915	COG0601	transmembrane transport
CFBP6625_RS23920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS23925	COG0405	Gamma-glutamyltransferase
CFBP6625_RS23935	COG4251	negative regulation of phosphorylation
CFBP6625_RS23940	COG0784	Response regulator, receiver
CFBP6625_RS23945	COG2202	Pas domain
CFBP6625_RS23945	COG3920	Histidine kinase
CFBP6625_RS23950	COG0784	Response regulator, receiver
CFBP6625_RS23955	COG2198	Histidine kinase
CFBP6625_RS23955	COG0784	Response regulator, receiver
CFBP6625_RS23955	COG5002	protein histidine kinase activity
CFBP6625_RS23960	COG0784	Response regulator, receiver
CFBP6625_RS23965	COG2204	response regulator
CFBP6625_RS23975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP6625_RS23980	COG3181	Tripartite tricarboxylate transporter family receptor
CFBP6625_RS23985	COG5265	(ABC) transporter
CFBP6625_RS23990	COG0640	Transcriptional regulator
CFBP6625_RS24000	COG3468	outer membrane autotransporter barrel domain protein
CFBP6625_RS24015	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CFBP6625_RS24025	COG1278	Cold shock
CFBP6625_RS24065	COG1192	Involved in chromosome partitioning
CFBP6625_RS24070	COG1475	DNA binding
CFBP6625_RS24075	COG0640	Transcriptional regulator
CFBP6625_RS24105	COG1522	sequence-specific DNA binding
CFBP6625_RS24150	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFBP6625_RS24165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFBP6625_RS24170	COG0066	3-isopropylmalate dehydratase activity
CFBP6625_RS24180	COG0473	3-isopropylmalate dehydrogenase activity
CFBP6625_RS24220	COG1196	nuclear chromosome segregation
CFBP6625_RS24230	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS24235	COG0583	DNA-binding transcription factor activity
CFBP6625_RS24245	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS24260	COG0028	Belongs to the TPP enzyme family
CFBP6625_RS24265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP6625_RS24275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP6625_RS24310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFBP6625_RS24320	COG0596	Alpha beta hydrolase
CFBP6625_RS24320	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP6625_RS24380	COG0765	amino acid transport
CFBP6625_RS24400	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS24405	COG0028	Belongs to the TPP enzyme family
CFBP6625_RS24420	COG0625	glutathione transferase activity
CFBP6625_RS24425	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFBP6625_RS24430	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CFBP6625_RS24440	COG1940	carbohydrate kinase activity
CFBP6625_RS24455	COG0395	ABC-type sugar transport system, permease component
CFBP6625_RS24510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS24515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP6625_RS24530	COG1846	Transcriptional regulator
CFBP6625_RS24530	COG1940	carbohydrate kinase activity
CFBP6625_RS24540	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS24570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP6625_RS24570	COG1116	anion transmembrane transporter activity
CFBP6625_RS24575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP6625_RS24585	COG0277	FAD linked oxidase domain protein
CFBP6625_RS24635	COG1733	regulation of RNA biosynthetic process
CFBP6625_RS24715	COG0587	DNA-directed DNA polymerase activity
CFBP6625_RS24730	COG3938	Belongs to the proline racemase family
CFBP6625_RS24735	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP6625_RS24740	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP6625_RS24745	COG4175	Glycine betaine
CFBP6625_RS24745	COG3448	diguanylate cyclase activity
CFBP6625_RS24755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP6625_RS24760	COG1012	belongs to the aldehyde dehydrogenase family
CFBP6625_RS24765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP6625_RS24815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP6625_RS24820	COG1475	DNA binding
CFBP6625_RS24850	COG4974	Belongs to the 'phage' integrase family
CFBP6625_RS24860	COG4974	Belongs to the 'phage' integrase family
CFBP6625_RS24870	COG2184	nucleotidyltransferase activity
CFBP6625_RS24990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP6625_RS25000	COG3547	Transposase (IS116 IS110 IS902 family)
CFBP6625_RS25025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CFBP6625_RS25040	COG1138	Cytochrome C-type biogenesis protein
CFBP6625_RS25055	COG1388	LysM domain
CFBP6625_RS25055	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6625_RS25080	COG2072	flavoprotein involved in K transport
CFBP6625_RS25085	COG3034	peptidoglycan biosynthetic process
CFBP6625_RS25115	COG0789	Transcriptional regulator
CFBP6625_RS25120	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP6625_RS25125	COG4584	PFAM Integrase catalytic
CFBP6625_RS25145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFBP6625_RS25155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP6625_RS25160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFBP6625_RS25170	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6625_RS25170	COG1388	LysM domain
CFBP6625_RS25180	COG0789	Transcriptional regulator
CFBP6625_RS25185	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP6625_RS25195	COG2217	Heavy metal translocating P-type atpase
CFBP6625_RS25205	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6625_RS25210	COG2194	sulfuric ester hydrolase activity
CFBP6625_RS25215	COG3034	peptidoglycan biosynthetic process
CFBP6625_RS25225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFBP6625_RS25230	COG1230	cation diffusion facilitator family transporter
CFBP6625_RS25235	COG3547	Transposase (IS116 IS110 IS902 family)
CFBP6625_RS25250	COG4644	lycopene metabolic process
CFBP6625_RS25255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6625_RS25265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6625_RS25295	COG3436	PFAM IS66 Orf2 family protein
CFBP6625_RS25365	COG1396	sequence-specific DNA binding
CFBP6625_RS25460	COG0739	heme binding
CFBP6625_RS25460	COG0741	lytic transglycosylase activity
CFBP6625_RS25460	COG1196	nuclear chromosome segregation
CFBP6625_RS25465	COG3451	type IV secretory pathway VirB4
CFBP6625_RS25475	COG3838	Conjugal transfer protein Trbc
CFBP6625_RS25480	COG0741	lytic transglycosylase activity
CFBP6625_RS25510	COG2948	multi-organism process
CFBP6625_RS25515	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CFBP6625_RS25580	COG1396	sequence-specific DNA binding
CFBP6625_RS25610	COG4644	lycopene metabolic process
CFBP6625_RS25615	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6625_RS25675	COG0741	lytic transglycosylase activity
CFBP6625_RS25685	COG2390	Transcriptional regulator
CFBP6625_RS25685	COG4584	PFAM Integrase catalytic
CFBP6625_RS25690	COG1484	DNA-dependent DNA replication
CFBP6625_RS25700	COG3451	type IV secretory pathway VirB4
CFBP6625_RS25705	COG0741	lytic transglycosylase activity
CFBP6625_RS25735	COG2948	multi-organism process
CFBP6625_RS25740	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CFBP6625_RS25785	COG0640	Transcriptional regulator
CFBP6625_RS25790	COG1475	DNA binding
CFBP6625_RS25795	COG1192	Involved in chromosome partitioning
CFBP6625_RS25800	COG4227	nucleotidyltransferase activity
CFBP6625_RS25805	COG4974	Belongs to the 'phage' integrase family
CFBP6625_RS25815	COG4974	Belongs to the 'phage' integrase family
CFBP6625_RS25830	COG5489	Protein of unknown function (DUF736)
CFBP6625_RS25850	COG5489	Protein of unknown function (DUF736)
CFBP6625_RS25860	COG5265	(ABC) transporter
CFBP6625_RS25890	COG3831	ATPase activity
CFBP6625_RS25900	COG0653	protein targeting
CFBP6625_RS25910	COG3505	Type IV secretory pathway VirD4
CFBP6625_RS25925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP6625_RS25930	COG4959	Type IV secretory pathway protease TraF
CFBP6625_RS25935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP6625_RS25955	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP6625_RS25960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6625_RS25965	COG2948	multi-organism process
CFBP6625_RS25975	COG3504	Conjugal transfer protein
CFBP6625_RS25980	COG3701	Conjugal transfer protein
CFBP6625_RS25985	COG3846	protein secretion by the type IV secretion system
CFBP6625_RS25995	COG5314	conjugation
CFBP6625_RS26000	COG3451	type IV secretory pathway VirB4
CFBP6625_RS26005	COG5268	conjugation
CFBP6625_RS26010	COG3838	Conjugal transfer protein Trbc
CFBP6625_RS26015	COG4962	Type ii secretion system protein e
CFBP6625_RS26020	COG1192	Involved in chromosome partitioning
CFBP6625_RS26025	COG1475	DNA binding
CFBP6625_RS26030	COG0640	Transcriptional regulator
CFBP6625_RS26035	COG1414	Transcriptional regulator
CFBP6625_RS26095	COG1695	Transcriptional regulator
CFBP6625_RS26105	COG3932	Exopolysaccharide synthesis, ExoD
CFBP6625_RS26110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFBP6625_RS26120	COG0640	Transcriptional regulator
CFBP6625_RS26135	COG0798	PFAM Bile acid sodium symporter
CFBP6625_RS26145	COG0431	NADPH-dependent FMN reductase
CFBP6625_RS26170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6625_RS26205	COG3300	MHYT domain
CFBP6625_RS26205	COG5001	Diguanylate cyclase
CFBP6625_RS26230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFBP6625_RS26250	COG0642	Histidine kinase
CFBP6625_RS26255	COG3046	protein related to deoxyribodipyrimidine photolyase
CFBP6625_RS26275	COG0840	transmembrane signaling receptor activity
CFBP6625_RS26295	COG0840	transmembrane signaling receptor activity
CFBP6625_RS26300	COG2972	Histidine kinase
CFBP6625_RS26300	COG0840	transmembrane signaling receptor activity
CFBP6625_RS26305	COG2197	response regulator
CFBP6625_RS26315	COG0835	chemotaxis
CFBP6625_RS26340	COG4644	lycopene metabolic process
CFBP6625_RS26345	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CFBP6625_RS26350	COG1126	abc transporter atp-binding protein
CFBP6625_RS26355	COG0765	amino acid transport
CFBP6625_RS26365	COG1609	Transcriptional regulator
CFBP6625_RS26370	COG2423	ornithine cyclodeaminase activity
CFBP6625_RS26375	COG2188	Transcriptional regulator
CFBP6625_RS26380	COG2222	sugar isomerase
CFBP6625_RS26385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP6625_RS26390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP6625_RS26400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP6625_RS26445	COG0405	Gamma-glutamyltransferase
CFBP6625_RS26450	COG0601	transmembrane transport
CFBP6625_RS26460	COG0444	Belongs to the ABC transporter superfamily
CFBP6625_RS26465	COG4608	Belongs to the ABC transporter superfamily
CFBP6625_RS26485	COG4372	Transposase
CFBP6625_RS26490	COG3436	PFAM IS66 Orf2 family protein
CFBP6625_RS26530	COG3547	Transposase (IS116 IS110 IS902 family)
CFBP6625_RS26545	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP6625_RS26600	COG0784	Response regulator, receiver
CFBP6625_RS26600	COG2205	protein histidine kinase activity
CFBP6625_RS26610	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CFBP6625_RS26615	COG2205	protein histidine kinase activity
CFBP6625_RS26615	COG2198	Histidine kinase
CFBP6625_RS26615	COG0784	Response regulator, receiver
CFBP6625_RS26635	COG2202	Pas domain
CFBP6625_RS26635	COG3920	Histidine kinase
CFBP6625_RS26650	COG2390	Transcriptional regulator
CFBP6625_RS26650	COG4584	PFAM Integrase catalytic
CFBP6625_RS26655	COG1484	DNA-dependent DNA replication
CFBP6625_RS26670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP6625_RS26675	COG1309	transcriptional regulator
CFBP6625_RS26680	COG0318	PFAM AMP-dependent synthetase and ligase
CFBP6625_RS26685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP6625_RS26710	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP6625_RS26725	COG2086	electron transfer activity
CFBP6625_RS26740	COG2801	Transposase and inactivated derivatives
CFBP6625_RS26760	COG0436	Aminotransferase
CFBP6625_RS26775	COG4215	(ABC) transporter
CFBP6625_RS26785	COG1126	abc transporter atp-binding protein
CFBP6625_RS26845	COG1484	DNA-dependent DNA replication
CFBP6625_RS26850	COG4584	PFAM Integrase catalytic
CFBP6625_RS26850	COG2390	Transcriptional regulator
CFBP6625_RS26885	COG2132	Multicopper oxidase
CFBP6625_RS26895	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6625_RS26925	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CFBP6625_RS26930	COG2948	multi-organism process
CFBP6625_RS26935	COG3504	Conjugal transfer protein
CFBP6625_RS26940	COG3736	Type IV secretory pathway, component VirB8
CFBP6625_RS26950	COG3704	protein secretion by the type IV secretion system
CFBP6625_RS26965	COG3451	type IV secretory pathway VirB4
CFBP6625_RS26970	COG3702	type iv secretory pathway
CFBP6625_RS26975	COG3838	Conjugal transfer protein Trbc
CFBP6625_RS27005	COG1414	Transcriptional regulator
CFBP6625_RS27020	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP6625_RS27025	COG3842	ATPase activity
CFBP6625_RS27035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CFBP6625_RS27040	COG0028	Belongs to the TPP enzyme family
CFBP6625_RS27045	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS27050	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS27060	COG0745	RESPONSE REGULATOR receiver
CFBP6625_RS27090	COG1396	sequence-specific DNA binding
CFBP6625_RS27115	COG3505	Type IV secretory pathway VirD4
CFBP6625_RS27120	COG3831	ATPase activity
CFBP6625_RS27165	COG5489	Protein of unknown function (DUF736)
CFBP6625_RS27235	COG0587	DNA-directed DNA polymerase activity
CFBP6625_RS27300	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6625_RS27330	COG3005	denitrification pathway
CFBP6625_RS27340	COG0243	molybdopterin cofactor binding
CFBP6625_RS27355	COG4459	periplasmic nitrate reductase
CFBP6625_RS27390	COG0826	peptidase U32
CFBP6625_RS27400	COG3189	MarR family transcriptional regulator
CFBP6625_RS27405	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CFBP6625_RS27440	COG3256	nitric oxide reductase
CFBP6625_RS27445	COG0714	Associated with various cellular activities
CFBP6625_RS27515	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CFBP6625_RS27560	COG3278	Belongs to the heme-copper respiratory oxidase family
CFBP6625_RS27575	COG2010	Cytochrome c
CFBP6625_RS27620	COG1846	Transcriptional regulator
CFBP6625_RS27645	COG0747	negative chemotaxis
CFBP6625_RS27660	COG0601	transmembrane transport
CFBP6625_RS27665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP6625_RS27680	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP6625_RS27690	COG3550	peptidyl-serine autophosphorylation
CFBP6625_RS27695	COG3620	sequence-specific DNA binding
CFBP6625_RS27745	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFBP6625_RS27770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6625_RS27785	COG4584	PFAM Integrase catalytic
CFBP6625_RS27805	COG0583	DNA-binding transcription factor activity
CFBP6625_RS27855	COG1609	Transcriptional regulator
CFBP6625_RS27875	COG3118	belongs to the thioredoxin family
CFBP6625_RS27910	COG0542	response to heat
CFBP6625_RS27920	COG1846	Transcriptional regulator
CFBP6625_RS27930	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6625_RS27935	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP6625_RS27975	COG3547	Transposase (IS116 IS110 IS902 family)
CFBP6625_RS27980	COG1484	DNA-dependent DNA replication
CFBP6625_RS27985	COG4584	PFAM Integrase catalytic
CFBP6625_RS27985	COG2390	Transcriptional regulator
CFBP6625_RS28000	COG1484	DNA-dependent DNA replication
CFBP6625_RS28030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6625_RS28035	COG4644	lycopene metabolic process
CFBP6625_RS28160	COG2948	multi-organism process
CFBP6625_RS28205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFBP6625_RS28260	COG1842	Phage shock protein A
CFBP6625_RS28305	COG0789	Transcriptional regulator
CFBP6625_RS28345	COG0789	Transcriptional regulator
CFBP6625_RS28370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6625_RS28440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP6625_RS28445	COG4644	lycopene metabolic process
CFBP6625_RS28460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP6625_RS28475	COG4644	lycopene metabolic process
CFBP6625_RS28505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFBP6625_RS28525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family