locus-tag	class	description
EML4_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
EML4_RS00010	ENOG4105CSA	Coproporphyrinogen iii oxidase
EML4_RS00015	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EML4_RS00020	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
EML4_RS00025	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
EML4_RS00030	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EML4_RS00035	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
EML4_RS00040	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
EML4_RS00045	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EML4_RS00050	ENOG4108IUZ	ABC transporter
EML4_RS00055	ENOG4105RF0	OstA family
EML4_RS00065	ENOG4105D07	Signal peptide peptidase, SppA
EML4_RS00070	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EML4_RS00080	ENOG4105DR4	Methyltransferase
EML4_RS00085	ENOG4108RWN	rrna methyltransferase
EML4_RS00090	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EML4_RS00095	ENOG4105BZU	Histidine kinase
EML4_RS00105	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EML4_RS00110	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
EML4_RS00115	ENOG4105CJR	Integral membrane protein (MviN
EML4_RS00125	ENOG4105C31	Tryptophanyl-tRNA synthetase
EML4_RS00135	ENOG41083MR	nifu domain-containing protein
EML4_RS00140	ENOG41072GX	Peptidase M22 Glycoprotease
EML4_RS00150	ENOG41090R7	Ferric uptake
EML4_RS00155	ENOG4108Z20	Acyl-transferase
EML4_RS00160	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EML4_RS00165	ENOG4105C9A	Phoh family
EML4_RS00170	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
EML4_RS00180	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
EML4_RS00185	ENOG4108WRK	Transcriptional regulator
EML4_RS00190	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EML4_RS00195	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EML4_RS00200	ENOG4108RVA	ribokinase
EML4_RS00205	ENOG4105CGY	Dna recombination protein
EML4_RS00210	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EML4_RS00215	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EML4_RS00220	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
EML4_RS00230	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EML4_RS00235	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
EML4_RS00250	ENOG4105DU0	nucleoside hydrolase
EML4_RS00255	ENOG4108ZNX	Heat shock protein
EML4_RS00280	ENOG4105CAS	nag kinase
EML4_RS00290	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EML4_RS00295	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EML4_RS00300	ENOG4105KK3	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
EML4_RS00325	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EML4_RS00330	ENOG4108IJ9	(ABC) transporter
EML4_RS00335	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
EML4_RS00340	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
EML4_RS00355	ENOG4105CYC	Transferase
EML4_RS00365	ENOG4105CTU	Proline racemase
EML4_RS00370	ENOG4105EKE	dihydroorotase
EML4_RS00375	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
EML4_RS00395	ENOG4105DBV	ornithine carbamoyltransferase
EML4_RS00400	ENOG4107QP8	phosphohexose isomerase
EML4_RS00405	ENOG4105CEY	Amp-dependent synthetase and ligase
EML4_RS00410	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS00415	ENOG4107QKW	extracellular solute-binding protein family 1
EML4_RS00420	ENOG4107Z6A	sulfate abc transporter permease
EML4_RS00425	ENOG4105E0K	tonB-dependent siderophore receptor
EML4_RS00465	ENOG4105D9P	serine threonine protein kinase
EML4_RS00520	ENOG4105CSR	polyphosphate kinase 2
EML4_RS00525	ENOG4105BZU	Histidine kinase
EML4_RS00530	ENOG4105PWN	phosphate abc transporter
EML4_RS00535	ENOG4105C8U	phosphate abc transporter
EML4_RS00545	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS00550	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
EML4_RS00555	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EML4_RS00565	ENOG4105C8Y	Acetylornithine aminotransferase
EML4_RS00570	ENOG4105DBV	ornithine carbamoyltransferase
EML4_RS00580	ENOG4105NWN	ApaG protein
EML4_RS00590	ENOG4105DHP	deoxycytidine triphosphate deaminase
EML4_RS00600	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
EML4_RS00605	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
EML4_RS00655	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
EML4_RS00670	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EML4_RS00690	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
EML4_RS00695	ENOG4107QRT	dEAD DEAH box helicase
EML4_RS00725	ENOG4105CSU	acyl-Coa dehydrogenase
EML4_RS00730	ENOG4105CHU	acetyl-coa acetyltransferase
EML4_RS00735	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EML4_RS00760	ENOG4105KJM	monovalent cation h antiporter subunit g
EML4_RS00765	ENOG4105W4C	monovalent cation H antiporter subunit F
EML4_RS00770	ENOG4105SC1	monovalent cation H antiporter subunit E
EML4_RS00775	ENOG4107R4Z	monovalent cation h antiporter subunit d
EML4_RS00780	ENOG4108ZE9	Monovalent cation H antiporter subunit C
EML4_RS00785	ENOG4105D65	subunit l
EML4_RS00795	ENOG4105UT3	Methyl-accepting chemotaxis
EML4_RS00810	ENOG4105CBS	Chea signal transduction histidine kinase
EML4_RS00815	ENOG4105BZU	Histidine kinase
EML4_RS00820	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
EML4_RS00825	ENOG4108VYJ	response regulator receiver protein
EML4_RS00830	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
EML4_RS00840	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
EML4_RS00845	ENOG4105VJY	transcriptional regulator
EML4_RS00860	ENOG4105BZU	Histidine kinase
EML4_RS00865	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
EML4_RS00870	ENOG4105CHM	Aminotransferase
EML4_RS00885	ENOG41086Q3	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
EML4_RS00890	ENOG4108Z03	MAF-like protein
EML4_RS00895	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
EML4_RS00905	ENOG4108ZTZ	UPF0262 protein
EML4_RS00910	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
EML4_RS00920	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EML4_RS00940	ENOG4107W75	Flagellin
EML4_RS00950	ENOG4105CN7	Flagellar biosynthetic protein FliP
EML4_RS00960	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
EML4_RS00970	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
EML4_RS00975	ENOG4105XZC	flagellar basal body P-ring biosynthesis protein FlgA
EML4_RS00980	ENOG4105CGA	flagellar basal-body rod protein FlgG
EML4_RS00985	ENOG4105X50	flagellar hook-basal body complex protein fliE
EML4_RS00990	ENOG4108ZC9	flagellar basal-body rod protein flgc
EML4_RS00995	ENOG4105SFI	flagellar basal-body rod protein
EML4_RS01005	ENOG4108JIR	Flagellum-specific ATP synthase
EML4_RS01010	ENOG4105KTQ	flagellar basal-body rod protein
EML4_RS01020	ENOG4107RD7	Flagellar Motor Protein, MotA
EML4_RS01030	ENOG4105DD5	Flagellar motor switch protein
EML4_RS01035	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
EML4_RS01040	ENOG4105D00	flagellar biosynthetic protein flhB
EML4_RS01045	ENOG4105QDQ	
EML4_RS01060	ENOG4105ER2	Ompa motb domain protein
EML4_RS01065	ENOG4108S15	chemotaxis, protein
EML4_RS01105	ENOG4105KHD	Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK mRNA and promotes its degradation (By similarity)
EML4_RS01110	ENOG410822I	Flagellar hook capping protein
EML4_RS01115	ENOG4105VS8	Flagellar biosynthetic protein fliq
EML4_RS01120	ENOG4105D7B	Flagellar biosynthesis protein flha
EML4_RS01125	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
EML4_RS01160	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EML4_RS01165	ENOG4105FKQ	transcriptional regulator
EML4_RS01170	ENOG4105EPJ	extracellular solute-binding protein family 1
EML4_RS01175	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
EML4_RS01180	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
EML4_RS01185	ENOG4105CG3	alpha amylase, catalytic region
EML4_RS01190	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS01205	ENOG4105C01	Dihydroxy-acid dehydratase
EML4_RS01210	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
EML4_RS01215	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EML4_RS01220	ENOG4105CJP	fad dependent oxidoreductase
EML4_RS01230	ENOG4105CBX	hi0933 family
EML4_RS01265	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS01270	ENOG4105F38	ABC transporter, permease
EML4_RS01275	ENOG4105D38	putrescine abc transporter
EML4_RS01285	ENOG4105BZU	Histidine kinase
EML4_RS01295	ENOG4105C9X	ppx gppa phosphatase
EML4_RS01300	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
EML4_RS01305	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EML4_RS01335	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
EML4_RS01340	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
EML4_RS01350	ENOG4105EAH	synthase
EML4_RS01375	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
EML4_RS01385	ENOG4108V0P	LemA family
EML4_RS01390	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
EML4_RS01400	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
EML4_RS01405	ENOG4105EWC	Purine nucleoside phosphorylase
EML4_RS01410	ENOG4105C8Q	Methyl-accepting chemotaxis
EML4_RS01420	ENOG4105C12	Phosphoribosylglycinamide synthetase
EML4_RS01425	ENOG4105BZM	domain protein
EML4_RS01430	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
EML4_RS01475	ENOG4105CJ3	phosphate transporter
EML4_RS01485	ENOG4108E2B	had-superfamily hydrolase, subfamily iib
EML4_RS01490	ENOG4107STW	synthase
EML4_RS01495	ENOG4105C6F	GntR Family Transcriptional Regulator
EML4_RS01505	ENOG410642W	LysR family Transcriptional regulator
EML4_RS01510	ENOG4105CQB	FAD linked oxidase domain protein
EML4_RS01520	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
EML4_RS01530	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
EML4_RS01535	ENOG4108R3E	Dna-3-methyladenine glycosylase i
EML4_RS01545	ENOG4105HMI	Membrane
EML4_RS01550	ENOG4108M0I	Transcriptional regulator
EML4_RS01580	ENOG4105CUT	histidyl-tRNA synthetase
EML4_RS01590	ENOG4105P5X	ATP phosphoribosyltransferase regulatory subunit
EML4_RS01595	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
EML4_RS01600	ENOG4108SB3	DoxX Family
EML4_RS01610	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EML4_RS01615	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
EML4_RS01625	ENOG4105DTN	riboflavin biosynthesis protein ribF
EML4_RS01630	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EML4_RS01640	ENOG4108Z6B	deaminase
EML4_RS01645	ENOG4105FE9	pseudouridine synthase
EML4_RS01650	ENOG4106H78	methyltransferase
EML4_RS01655	ENOG4105D78	K07001 NTE family protein
EML4_RS01665	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
EML4_RS01670	ENOG4107TK4	histidinol-phosphate phosphatase
EML4_RS01680	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
EML4_RS01690	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
EML4_RS01705	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EML4_RS01710	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EML4_RS01715	ENOG4105BZU	Histidine kinase
EML4_RS01720	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
EML4_RS01725	ENOG4108RTU	Aldolase
EML4_RS01730	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
EML4_RS01735	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
EML4_RS01740	ENOG4107HP6	Transcriptional regulator
EML4_RS01745	ENOG4107WYG	Transcriptional regulator, luxr family
EML4_RS01755	ENOG4105D1F	ATP-binding protein
EML4_RS01760	ENOG4107QUT	magnesium and cobalt transport protein CorA
EML4_RS01765	ENOG4105DFH	Transport of potassium into the cell (By similarity)
EML4_RS01780	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
EML4_RS01785	ENOG4105VD1	ATP synthase subunit C
EML4_RS01790	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EML4_RS01810	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EML4_RS01830	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EML4_RS01840	ENOG4105DVW	rieske (2Fe-2S)
EML4_RS01850	ENOG4105W6J	BA14K family
EML4_RS01855	ENOG4105W6J	BA14K family
EML4_RS01865	ENOG4105CSU	acyl-Coa dehydrogenase
EML4_RS01880	ENOG4107QS4	23S rRNA
EML4_RS01885	ENOG4105DX0	Hemolysin A
EML4_RS01890	ENOG4105C8Q	Methyl-accepting chemotaxis
EML4_RS01900	ENOG4105FKN	transcriptional regulator, AsnC family
EML4_RS01925	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
EML4_RS01930	ENOG4105EUB	pirin domain protein
EML4_RS01935	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EML4_RS01945	ENOG4107ZYJ	bioY protein
EML4_RS01950	ENOG4107QCX	Transporter
EML4_RS01955	ENOG4108JJB	ABC transporter
EML4_RS01960	ENOG4105T0Z	Conserved Protein
EML4_RS01970	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EML4_RS01990	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
EML4_RS02005	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
EML4_RS02025	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
EML4_RS02035	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
EML4_RS02045	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
EML4_RS02050	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EML4_RS02055	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
EML4_RS02060	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
EML4_RS02065	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
EML4_RS02075	ENOG4108R6F	Surfeit locus 1 family protein
EML4_RS02080	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
EML4_RS02085	ENOG4105CUV	Homoserine Kinase
EML4_RS02090	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EML4_RS02100	ENOG4105EHV	domain protein
EML4_RS02110	ENOG4108UJU	UPF0301 protein
EML4_RS02115	ENOG4108J08	Csbd family
EML4_RS02125	ENOG4105BZU	Histidine kinase
EML4_RS02130	ENOG4105D9U	N-acetyltransferase
EML4_RS02140	ENOG4105D98	threonine synthase
EML4_RS02160	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
EML4_RS02165	ENOG4108PVQ	transcriptional regulator
EML4_RS02180	ENOG4105CEC	DNA methylase N-4 N-6
EML4_RS02185	ENOG4105YAJ	CopG Arc MetJ
EML4_RS02190	ENOG4105KRP	Plasmid stabilization system
EML4_RS02200	ENOG4105CEN	a g-specific adenine glycosylase
EML4_RS02215	ENOG4108R9S	DSBA oxidoreductase
EML4_RS02220	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EML4_RS02225	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
EML4_RS02230	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
EML4_RS02245	ENOG4108ETY	sodium dicarboxylate symporter
EML4_RS02275	ENOG4105DWT	malate dehydrogenase (quinone)
EML4_RS02290	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
EML4_RS02295	ENOG4105C11	sulfate adenylyltransferase), subunit 2
EML4_RS02300	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
EML4_RS02305	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
EML4_RS02310	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
EML4_RS02315	ENOG4108I5D	sulfate abc transporter
EML4_RS02325	ENOG4108IJ6	ABC transporter
EML4_RS02335	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
EML4_RS02345	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
EML4_RS02350	ENOG4105C26	Dehydrogenase
EML4_RS02355	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
EML4_RS02390	ENOG4107MKT	Stringent starvation protein a
EML4_RS02400	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EML4_RS02410	ENOG4107T0X	DNA ligase
EML4_RS02420	ENOG4108ST3	glycosyltransferase
EML4_RS02430	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
EML4_RS02435	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
EML4_RS02440	ENOG4105K56	Transcriptional regulator
EML4_RS02445	ENOG4108ZHJ	Organic hydroperoxide resistance protein
EML4_RS02460	ENOG4105C5H	ABC transporter
EML4_RS02490	ENOG4105EQ2	LysR family Transcriptional regulator
EML4_RS02495	ENOG4105EMU	Dehydrogenase
EML4_RS02510	ENOG4105D7A	ATP-binding protein
EML4_RS02520	ENOG4105KVH	Transcriptional regulator
EML4_RS02525	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
EML4_RS02540	ENOG4105CV8	reductase
EML4_RS02545	ENOG4105FFC	UPF0187 protein
EML4_RS02550	ENOG4105D29	Helix-turn-helix type 11 domain protein
EML4_RS02560	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
EML4_RS02565	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EML4_RS02570	ENOG4105C8Q	Methyl-accepting chemotaxis
EML4_RS02590	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EML4_RS02605	ENOG4108NIW	Leucine export protein LeuE
EML4_RS02610	ENOG4105TAV	cytochrome C
EML4_RS02615	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
EML4_RS02670	ENOG4108IJ7	Glycine betaine
EML4_RS02675	ENOG4108HQS	Glycine betaine
EML4_RS02705	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EML4_RS02715	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
EML4_RS02735	ENOG4108UT2	hemolysin iii
EML4_RS02745	ENOG410829K	Lysine exporter protein (Lyse ygga)
EML4_RS02750	ENOG4105E0X	reductase
EML4_RS02755	ENOG4105D65	subunit l
EML4_RS02760	ENOG4105HC0	Na H antiporter
EML4_RS02765	ENOG4108ZE9	Monovalent cation H antiporter subunit C
EML4_RS02770	ENOG4108JPZ	Monovalent cation H antiporter subunit D
EML4_RS02775	ENOG4105SC1	monovalent cation H antiporter subunit E
EML4_RS02780	ENOG41080TA	Multiple resistance and ph regulation protein f
EML4_RS02785	ENOG4105KJM	monovalent cation h antiporter subunit g
EML4_RS02790	ENOG4108YXV	Transcriptional regulator
EML4_RS02805	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
EML4_RS02810	ENOG4105WZR	
EML4_RS02815	ENOG4105BZU	Histidine kinase
EML4_RS02855	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
EML4_RS02860	ENOG4108JQC	penicillin-binding protein 1A
EML4_RS02865	ENOG4108ZZ3	UPF0260 protein
EML4_RS02915	ENOG4105F27	Major Facilitator
EML4_RS02930	ENOG4105CNG	UPF0061 protein
EML4_RS02940	ENOG4105EW9	transcriptional regulator AsnC family
EML4_RS03070	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EML4_RS03085	ENOG4106FI7	cytochrome c-type biogenesis protein
EML4_RS03090	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
EML4_RS03095	ENOG4105DA4	cytochrome c-type biogenesis protein
EML4_RS03100	ENOG4105KWW	Biogenesis protein
EML4_RS03105	ENOG4105C0H	protease
EML4_RS03110	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EML4_RS03115	ENOG4105JJR	Histidine kinase
EML4_RS03120	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
EML4_RS03125	ENOG4105Z4Q	MltA-interacting MipA family protein
EML4_RS03130	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
EML4_RS03135	ENOG4105BZU	Histidine kinase
EML4_RS03145	ENOG4105CD8	aminopeptidase N
EML4_RS03150	ENOG4108EHX	EamA-like transporter family
EML4_RS03165	ENOG4105R8A	Heat shock protein
EML4_RS03175	ENOG4105CHR	reductase
EML4_RS03190	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EML4_RS03200	ENOG4105CIS	alcohol dehydrogenase
EML4_RS03205	ENOG4105KVH	Transcriptional regulator
EML4_RS03210	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EML4_RS03215	ENOG4105CJW	magnesium transporter
EML4_RS03220	ENOG4105F27	Major Facilitator
EML4_RS03230	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EML4_RS03245	ENOG4105FYV	Amp nucleosidase
EML4_RS03275	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EML4_RS03325	ENOG4107SC1	transglycosylase
EML4_RS03330	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EML4_RS03335	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
EML4_RS03340	ENOG4105UT3	Methyl-accepting chemotaxis
EML4_RS03350	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
EML4_RS03370	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
EML4_RS03375	ENOG4105C3F	Signal peptidase i
EML4_RS03380	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
EML4_RS03385	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
EML4_RS03395	ENOG41074H6	response regulator
EML4_RS03400	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
EML4_RS03410	ENOG4105DMQ	Methyltransferase
EML4_RS03415	ENOG4105QVC	MOSC domain-containing protein
EML4_RS03420	ENOG4105EST	Metal Dependent Phosphohydrolase
EML4_RS03445	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
EML4_RS03450	ENOG4108MEK	Metal-binding protein YodA
EML4_RS03455	ENOG4105D64	Mechanosensitive ion channel
EML4_RS03465	ENOG4108R7K	Metal Dependent Phosphohydrolase
EML4_RS03495	ENOG4105KK4	UPF0060 membrane protein
EML4_RS03510	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
EML4_RS03515	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
EML4_RS03520	ENOG4108JJ7	ABC transporter
EML4_RS03530	ENOG4108URH	decarboxylase
EML4_RS03540	ENOG4105FR1	rard protein
EML4_RS03560	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
EML4_RS03565	ENOG4105C8N	cysteinyl-tRNA synthetase
EML4_RS03570	ENOG4105PDP	Short chain dehydrogenase
EML4_RS03575	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EML4_RS03580	ENOG4105E96	Colicin v production protein
EML4_RS03600	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EML4_RS03605	ENOG4105E7U	AraC family transcriptional regulator
EML4_RS03610	ENOG4108UMN	azlc family
EML4_RS03620	ENOG4105CDU	Replicative dna helicase
EML4_RS03640	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
EML4_RS03650	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
EML4_RS03655	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
EML4_RS03665	ENOG4105CPC	Aldo Keto reductase
EML4_RS03670	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
EML4_RS03680	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EML4_RS03685	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EML4_RS03695	ENOG4105HHA	aminodeoxychorismate lyase
EML4_RS03700	ENOG4105DSJ	YicC domain protein
EML4_RS03705	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EML4_RS03720	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EML4_RS03725	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
EML4_RS03735	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
EML4_RS03750	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EML4_RS03760	ENOG4105BZU	Histidine kinase
EML4_RS03775	ENOG4105BZU	Histidine kinase
EML4_RS03780	ENOG4105BZU	Histidine kinase
EML4_RS03785	ENOG4108ZXC	Two component transcriptional regulator, luxr family
EML4_RS03795	ENOG4105C5H	ABC transporter
EML4_RS03800	ENOG4105BZU	Histidine kinase
EML4_RS03810	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EML4_RS03830	ENOG4108ZAF	Molybdopterin
EML4_RS03845	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EML4_RS03850	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
EML4_RS03855	ENOG4105JVC	membrAne
EML4_RS03875	ENOG4105D6S	protein involved in catabolism of external DNA
EML4_RS03880	ENOG4107QY8	reductase
EML4_RS03885	ENOG4107VIJ	nudix hydrolase
EML4_RS03905	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EML4_RS03910	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EML4_RS03920	ENOG4105C02	permease
EML4_RS03930	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
EML4_RS03935	ENOG4105C9X	ppx gppa phosphatase
EML4_RS03960	ENOG4108Q35	Adenylate
EML4_RS03970	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
EML4_RS03975	ENOG4108ISG	Major Facilitator
EML4_RS03980	ENOG4105C9M	aspartyl-trna synthetase
EML4_RS03995	ENOG4105CHH	sulfate transporter
EML4_RS04005	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EML4_RS04010	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
EML4_RS04020	ENOG4105D52	delta-aminolevulinic acid dehydratase
EML4_RS04040	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EML4_RS04045	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
EML4_RS04050	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
EML4_RS04065	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EML4_RS04070	ENOG4107XZX	Involved in the transcription termination process (By similarity)
EML4_RS04075	ENOG4105DXI	Major Facilitator superfamily
EML4_RS04080	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EML4_RS04100	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
EML4_RS04105	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EML4_RS04110	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EML4_RS04115	ENOG4105WJX	transcriptional regulator MERR family
EML4_RS04145	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS04150	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS04155	ENOG4105C3U	ABC transporter
EML4_RS04165	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS04175	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
EML4_RS04180	ENOG4105C7B	Threonine dehydratase
EML4_RS04195	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
EML4_RS04200	ENOG4105HEI	LysR family (Transcriptional regulator
EML4_RS04205	ENOG4105CGH	5'-nucleotidase
EML4_RS04225	ENOG4105KHC	sulfurtransferase
EML4_RS04240	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EML4_RS04250	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EML4_RS04280	ENOG4108TPP	exopolysaccharide synthesis
EML4_RS04285	ENOG4108UM1	dedA family
EML4_RS04330	ENOG4105D3Q	Sugar transferase
EML4_RS04335	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
EML4_RS04360	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
EML4_RS04370	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
EML4_RS04375	ENOG4105CYW	agmatinase
EML4_RS04380	ENOG4108UJD	30S ribosomal protein S9
EML4_RS04385	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EML4_RS04395	ENOG4105K4P	CoA-binding domain protein
EML4_RS04420	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
EML4_RS04425	ENOG4106A3M	Cytochrome p-450
EML4_RS04430	ENOG4105BZU	Histidine kinase
EML4_RS04435	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EML4_RS04440	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EML4_RS04445	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EML4_RS04480	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EML4_RS04485	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EML4_RS04490	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EML4_RS04500	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EML4_RS04510	ENOG4105GKE	subunit e
EML4_RS04515	ENOG4107QIZ	NADH dehydrogenase
EML4_RS04520	ENOG4107R0R	NADH dehydrogenase subunit g
EML4_RS04525	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
EML4_RS04530	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EML4_RS04535	ENOG4105DF2	NADH dehydrogenase subunit j
EML4_RS04540	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EML4_RS04545	ENOG4105D65	subunit l
EML4_RS04550	ENOG4105C8S	subunit m
EML4_RS04555	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EML4_RS04560	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
EML4_RS04575	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EML4_RS04585	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EML4_RS04600	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EML4_RS04620	ENOG4108UXN	response regulator
EML4_RS04630	ENOG4105W0E	50S ribosomal protein L33
EML4_RS04635	ENOG4108ISG	Major Facilitator
EML4_RS04650	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EML4_RS04665	ENOG4105C79	DNA protecting protein DprA
EML4_RS04670	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
EML4_RS04675	ENOG4105CD3	dihydroorotase
EML4_RS04680	ENOG4105CXT	aspartate transcarbamylase
EML4_RS04695	ENOG4105CSU	acyl-Coa dehydrogenase
EML4_RS04700	ENOG4108ZBR	Gcn5-related n-acetyltransferase
EML4_RS04720	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
EML4_RS04725	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
EML4_RS04730	ENOG4107T8T	UPF0173 metal-dependent hydrolase
EML4_RS04735	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EML4_RS04740	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EML4_RS04745	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
EML4_RS04750	ENOG4105YCT	UPF0386 protein
EML4_RS04765	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EML4_RS04775	ENOG410849A	acetyltransferase, (GNAT) family
EML4_RS04795	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
EML4_RS04800	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EML4_RS04805	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EML4_RS04810	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
EML4_RS04840	ENOG4105CHR	reductase
EML4_RS04845	ENOG4105C03	ribonuclease
EML4_RS04850	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
EML4_RS04875	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EML4_RS04880	ENOG4105JAB	phenazine biosynthesis protein, phzf family
EML4_RS04900	ENOG4107Z7P	Ferredoxin
EML4_RS04910	ENOG4105EEI	dihydropteroate synthase
EML4_RS04915	ENOG4105KRF	dihydroneopterin aldolase
EML4_RS04920	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EML4_RS04930	ENOG4106K28	UPF0283 membrane protein
EML4_RS04935	ENOG4105CM6	amino acid regulated cytosolic protein
EML4_RS04965	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
EML4_RS05000	ENOG4105K59	histidine triad (HIT) protein
EML4_RS05025	ENOG4105CE9	30S ribosomal protein S2
EML4_RS05030	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
EML4_RS05035	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
EML4_RS05040	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EML4_RS05045	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
EML4_RS05055	ENOG4105DZP	Membrane-associated zinc metalloprotease
EML4_RS05060	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EML4_RS05065	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EML4_RS05070	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EML4_RS05075	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EML4_RS05080	ENOG4105GYT	Protein of unknown function (DUF1009)
EML4_RS05085	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EML4_RS05090	ENOG41073TP	transcriptional regulator
EML4_RS05100	ENOG4105E5Q	amino acid AbC transporter
EML4_RS05105	ENOG4105E5Q	amino acid AbC transporter
EML4_RS05115	ENOG4105BZN	citrate synthase
EML4_RS05130	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
EML4_RS05140	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EML4_RS05145	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EML4_RS05155	ENOG4108JYK	Dehydrogenase
EML4_RS05160	ENOG4105CPP	Dehydrogenase, E1 component
EML4_RS05165	ENOG4105C7S	Dehydrogenase
EML4_RS05175	ENOG4107QN2	dihydrolipoyl dehydrogenase
EML4_RS05185	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EML4_RS05190	ENOG4105DXC	membrane
EML4_RS05210	ENOG4108Z1B	Cyclase dehydrase
EML4_RS05215	ENOG4105CEV	competence damage-inducible protein
EML4_RS05220	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
EML4_RS05230	ENOG4105CUX	Signal transduction histidine kinase
EML4_RS05235	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EML4_RS05240	ENOG4105ES5	Histidine kinase
EML4_RS05245	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EML4_RS05250	ENOG4105C1A	potassium transporter peripheral membrane
EML4_RS05255	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
EML4_RS05260	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EML4_RS05265	ENOG4105DXN	mazG family
EML4_RS05275	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EML4_RS05295	ENOG4105DP0	ferredoxin-NADP reductase
EML4_RS05315	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EML4_RS05320	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EML4_RS05325	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EML4_RS05350	ENOG41082CG	Protein CrcB homolog
EML4_RS05355	ENOG4105EI2	Pseudouridine synthase
EML4_RS05360	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EML4_RS05375	ENOG4108UQ8	endoribonuclease L-psp
EML4_RS05380	ENOG4105C4W	S-formylglutathione hydrolase
EML4_RS05390	ENOG4108UPT	UPF0178 protein
EML4_RS05405	ENOG4105D3R	alkyl hydroperoxide reductase
EML4_RS05415	ENOG4105CYM	Glutathione S-transferase
EML4_RS05435	ENOG4105F9F	transposase
EML4_RS05440	ENOG4105CAU	Arsenical resistance protein, ArsH
EML4_RS05450	ENOG4105D6J	arsenicaL-resistance protein
EML4_RS05470	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EML4_RS05475	ENOG4105F8V	Hydrolase, tatD family
EML4_RS05480	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EML4_RS05485	ENOG4107QRG	dna polymerase iii
EML4_RS05490	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EML4_RS05495	ENOG4105DZ1	carboxypeptidase
EML4_RS05545	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EML4_RS05550	ENOG41081FY	multiple antibiotic resistance (MarC)-related
EML4_RS05565	ENOG4108UUM	single-stranded DNA-binding protein
EML4_RS05570	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
EML4_RS05580	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EML4_RS05590	ENOG4108Z0R	Transferase
EML4_RS05600	ENOG4105FAV	ABC, transporter
EML4_RS05605	ENOG4105FDK	ABC transporter
EML4_RS05615	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS05625	ENOG4105CPC	Aldo Keto reductase
EML4_RS05635	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
EML4_RS05715	ENOG4105CJW	magnesium transporter
EML4_RS05720	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
EML4_RS05730	ENOG4108XEG	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EML4_RS05745	ENOG4105BZU	Histidine kinase
EML4_RS05755	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EML4_RS05760	ENOG4105DQ4	alcohol dehydrogenase
EML4_RS05790	ENOG4105VIE	preprotein translocase, subunit YajC
EML4_RS05800	ENOG4105E2A	Dehydrogenase
EML4_RS05805	ENOG41062JF	Transcriptional regulator
EML4_RS05820	ENOG4105D7W	serine acetyltransferase
EML4_RS05835	ENOG4105MSY	salicylate hydroxylase
EML4_RS05840	ENOG4105C28	cystathionine
EML4_RS05845	ENOG4107QXX	ABC transporter
EML4_RS05850	ENOG4105EZ7	amino acid ABC transporter
EML4_RS05855	ENOG4105DRP	amino acid AbC transporter
EML4_RS05860	ENOG4105CDA	abc transporter atp-binding protein
EML4_RS05880	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
EML4_RS05890	ENOG4105D6E	homoserine dehydrogenase
EML4_RS05895	ENOG4105CHM	Aminotransferase
EML4_RS05925	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EML4_RS05935	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EML4_RS05940	ENOG4105J3Q	acyl carrier protein
EML4_RS05945	ENOG4105D4P	Coproporphyrinogen iii oxidase
EML4_RS05950	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EML4_RS05960	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
EML4_RS05965	ENOG4105PW4	Sugar fermentation stimulation protein homolog
EML4_RS05970	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EML4_RS05990	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
EML4_RS06015	ENOG4105E66	phosphoriboisomerase A
EML4_RS06020	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EML4_RS06030	ENOG4105C9Q	fumarate hydratase class II
EML4_RS06040	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EML4_RS06045	ENOG4107EJC	Preprotein translocase subunit SecG
EML4_RS06050	ENOG4105CP7	Triose-phosphate isomerase
EML4_RS06060	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EML4_RS06070	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EML4_RS06080	ENOG4105KBH	arsR family transcriptional regulator
EML4_RS06085	ENOG4107RZC	phospholipase d
EML4_RS06110	ENOG4105EGS	Mechanosensitive ion channel
EML4_RS06175	ENOG4105DHJ	ABC, transporter
EML4_RS06180	ENOG4105CY3	ABC transporter, permease
EML4_RS06185	ENOG4107S8C	mandelate racemase muconate lactonizing
EML4_RS06195	ENOG4105C6K	Malic enzyme
EML4_RS06205	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
EML4_RS06210	ENOG4108MR6	WD40-like Beta Propeller Repeat
EML4_RS06220	ENOG4105C4K	Nad synthetase
EML4_RS06225	ENOG4107T7U	Sulfatase
EML4_RS06250	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
EML4_RS06270	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
EML4_RS06290	ENOG4107QPD	alcohol dehydrogenase
EML4_RS06305	ENOG4105CEY	Amp-dependent synthetase and ligase
EML4_RS06320	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EML4_RS06325	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
EML4_RS06340	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EML4_RS06355	ENOG4108I0Q	anthranilate phosphoribosyltransferase
EML4_RS06360	ENOG4105DK0	Indole-3-glycerol phosphate synthase
EML4_RS06365	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EML4_RS06370	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EML4_RS06375	ENOG4105BZU	Histidine kinase
EML4_RS06385	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
EML4_RS06395	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EML4_RS06405	ENOG4105CZQ	inner membrane transport protein YdhC
EML4_RS06410	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
EML4_RS06415	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
EML4_RS06420	ENOG4105DR5	peptidase
EML4_RS06425	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EML4_RS06430	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
EML4_RS06435	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EML4_RS06440	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
EML4_RS06450	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
EML4_RS06455	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
EML4_RS06460	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
EML4_RS06465	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
EML4_RS06475	ENOG4105C75	arginyL-tRNA synthetase
EML4_RS06480	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
EML4_RS06495	ENOG4108UQD	Sel1 domain protein repeat-containing protein
EML4_RS06505	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
EML4_RS06515	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EML4_RS06545	ENOG4105CS1	NAD(P)H quinone oxidoreductase
EML4_RS06550	ENOG4107TH8	cina domain protein
EML4_RS06560	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
EML4_RS06570	ENOG4107RTZ	reductase
EML4_RS06580	ENOG4108A65	Transcriptional regulator
EML4_RS06585	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
EML4_RS06595	ENOG4105BZ1	(ABC) transporter
EML4_RS06600	ENOG4105IPI	Membrane
EML4_RS06635	ENOG4105C22	threonyL-tRNA synthetase
EML4_RS06645	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
EML4_RS06655	ENOG4105EUJ	GTP cyclohydrolase i
EML4_RS06660	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EML4_RS06665	ENOG4105D78	K07001 NTE family protein
EML4_RS06675	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EML4_RS06710	ENOG4105EJQ	L-serine dehydratase
EML4_RS06755	ENOG4105ECQ	AraC Family Transcriptional Regulator
EML4_RS06760	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
EML4_RS06775	ENOG4105C5F	glutamine synthetase
EML4_RS06785	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
EML4_RS06805	ENOG4108JHT	EamA-like transporter family
EML4_RS06825	ENOG4105CB5	ATP-dependent DNA helicase recG
EML4_RS06855	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EML4_RS06865	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EML4_RS06870	ENOG4107EJG	GntR family transcriptional regulator
EML4_RS06885	ENOG4105UIB	(ABC) transporter
EML4_RS06890	ENOG4105C2J	ABC transporter
EML4_RS06895	ENOG4105VE1	Phosphatidylcholine synthase
EML4_RS06905	ENOG4105RK9	auxin efflux carrier
EML4_RS06910	ENOG4107QIV	Cytochrome c biogenesis protein
EML4_RS06995	ENOG4108R7K	Metal Dependent Phosphohydrolase
EML4_RS07110	ENOG4108Z9Z	response to DNA damage stimulus
EML4_RS07125	ENOG4105K8R	UPF0145 protein
EML4_RS07185	ENOG4105D07	Signal peptide peptidase, SppA
EML4_RS07240	ENOG4105D9P	serine threonine protein kinase
EML4_RS07250	ENOG4105VDW	Csbd family
EML4_RS07260	ENOG4107RHI	Cytosine-specific methyltransferase
EML4_RS07290	ENOG4105CFI	type iii restriction protein res subunit
EML4_RS07295	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EML4_RS07405	ENOG4108I1J	Integrase
EML4_RS07425	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EML4_RS07430	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EML4_RS07450	ENOG4105QAS	Iron-sulfur cluster assembly accessory protein
EML4_RS07455	ENOG4105VG1	fes assembly suf system protein
EML4_RS07465	ENOG4105JRK	feS assembly protein SufD
EML4_RS07480	ENOG4105C3J	Cysteine desulfurase
EML4_RS07485	ENOG4105DHZ	alpha beta
EML4_RS07490	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
EML4_RS07495	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EML4_RS07505	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EML4_RS07510	ENOG4105ED9	Protein of unknown function (DUF455)
EML4_RS07515	ENOG4105DR5	peptidase
EML4_RS07520	ENOG4105C1J	atp-dependent rna helicase
EML4_RS07535	ENOG4105DJV	ribulose-phosphate 3-epimerase
EML4_RS07545	ENOG4105C83	adenylosuccinate lyase
EML4_RS07555	ENOG4107QPR	SAICAR synthetase
EML4_RS07560	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
EML4_RS07565	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
EML4_RS07580	ENOG4107SQD	Transcriptional regulator, GntR family
EML4_RS07585	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
EML4_RS07615	ENOG4105C2C	drug resistance transporter, Bcr CflA
EML4_RS07620	ENOG4105ECY	inositol monophosphatase
EML4_RS07625	ENOG4108MWI	inositol mono-phosphatase
EML4_RS07630	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
EML4_RS07635	ENOG4105CSV	Glutaminase
EML4_RS07640	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EML4_RS07645	ENOG4105DU1	integral membrane protein, terc
EML4_RS07655	ENOG4108594	Permease of the drug metabolite transporter
EML4_RS07660	ENOG410829K	Lysine exporter protein (Lyse ygga)
EML4_RS07670	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
EML4_RS07675	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
EML4_RS07695	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EML4_RS07700	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
EML4_RS07705	ENOG4107UH8	sugar kinase
EML4_RS07710	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
EML4_RS07720	ENOG4106TNF	Periplasmic binding protein
EML4_RS07725	ENOG4105GBT	ABC transporter
EML4_RS07735	ENOG4105P0T	Usg family
EML4_RS07745	ENOG4105GVF	(ABC) transporter
EML4_RS07750	ENOG4108XM1	transcriptional regulator AsnC family
EML4_RS07755	ENOG4108RG0	uracil-dna glycosylase
EML4_RS07765	ENOG4105BZU	Histidine kinase
EML4_RS07770	ENOG41085FU	Diacylglycerol kinase
EML4_RS07775	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
EML4_RS07780	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
EML4_RS07795	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EML4_RS07800	ENOG4105E3A	(ABC) transporter
EML4_RS07805	ENOG4105DA5	(ABC) transporter
EML4_RS07830	ENOG4105D1H	recombination factor protein RarA
EML4_RS07835	ENOG4105C0H	protease
EML4_RS07855	ENOG4105C01	Dihydroxy-acid dehydratase
EML4_RS07860	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
EML4_RS07865	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
EML4_RS07875	ENOG4105NX3	Membrane
EML4_RS07885	ENOG4108ZT0	50S ribosomal protein l17
EML4_RS07890	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EML4_RS07895	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EML4_RS07900	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EML4_RS07905	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EML4_RS07910	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
EML4_RS07915	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EML4_RS07920	ENOG41084HQ	50S ribosomal protein L30
EML4_RS07925	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EML4_RS07930	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
EML4_RS07935	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EML4_RS07940	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EML4_RS07945	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EML4_RS07950	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EML4_RS07955	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
EML4_RS07960	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EML4_RS07965	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
EML4_RS07970	ENOG41083MP	50s ribosomal protein l29
EML4_RS07975	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EML4_RS07980	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EML4_RS07985	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EML4_RS07990	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EML4_RS07995	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EML4_RS08000	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
EML4_RS08005	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EML4_RS08010	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EML4_RS08015	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
EML4_RS08020	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EML4_RS08025	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EML4_RS08030	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EML4_RS08035	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EML4_RS08055	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EML4_RS08060	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EML4_RS08065	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EML4_RS08070	ENOG4108VZM	50s ribosomal protein L10
EML4_RS08075	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EML4_RS08080	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EML4_RS08090	ENOG410683Z	Preprotein translocase SecE subunit
EML4_RS08100	ENOG4105C5E	polysaccharide biosynthesis protein
EML4_RS08105	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EML4_RS08110	ENOG4108ZCF	integral membrane protein
EML4_RS08115	ENOG41069B0	Membrane-bound lysozyme-inhibitor of c-type lysozyme
EML4_RS08135	ENOG4105BZ1	(ABC) transporter
EML4_RS08140	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
EML4_RS08160	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
EML4_RS08190	ENOG4107QQR	Sporulation
EML4_RS08195	ENOG4105BZU	Histidine kinase
EML4_RS08200	ENOG41074H6	response regulator
EML4_RS08205	ENOG4105BZU	Histidine kinase
EML4_RS08215	ENOG4105BZU	Histidine kinase
EML4_RS08230	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EML4_RS08235	ENOG4105NAU	thioesterase Superfamily protein
EML4_RS08255	ENOG4108RYK	Nad-dependent epimerase dehydratase
EML4_RS08260	ENOG4105KVH	Transcriptional regulator
EML4_RS08275	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
EML4_RS08285	ENOG4105DYC	esterase
EML4_RS08305	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EML4_RS08325	ENOG4105BZU	Histidine kinase
EML4_RS08335	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS08345	ENOG4107QKW	extracellular solute-binding protein family 1
EML4_RS08350	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EML4_RS08365	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
EML4_RS08375	ENOG4105CF7	AraC family transcriptional regulator
EML4_RS08380	ENOG4105DQ4	alcohol dehydrogenase
EML4_RS08385	ENOG4105CEP	NADH dehydrogenase
EML4_RS08390	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
EML4_RS08395	ENOG4105VJY	transcriptional regulator
EML4_RS08400	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
EML4_RS08435	ENOG4105CV8	reductase
EML4_RS08450	ENOG4108ZP8	Acetolactate synthase small subunit
EML4_RS08455	ENOG4105C7K	acetolactate synthase
EML4_RS08470	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EML4_RS08475	ENOG4105EAC	phosphoserine phosphatase
EML4_RS08480	ENOG4108YYQ	gCN5-related N-acetyltransferase
EML4_RS08495	ENOG4105EPW	hflc protein
EML4_RS08500	ENOG4107QJR	hflk protein
EML4_RS08510	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
EML4_RS08545	ENOG4105CQB	FAD linked oxidase domain protein
EML4_RS08550	ENOG4105BZS	acriflavin resistance protein
EML4_RS08555	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
EML4_RS08590	ENOG4108RWI	nicotinamidase
EML4_RS08620	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EML4_RS08625	ENOG4108ZX6	Electron transport protein SCO1 SenC
EML4_RS08635	ENOG4108V3W	Chemotaxis protein, CheW
EML4_RS08645	ENOG41083X2	DNA polymerase III, epsilon subunit
EML4_RS08650	ENOG4105ETT	transcriptional Regulator, LysR family
EML4_RS08660	ENOG4105WCN	acetyltransferase
EML4_RS08670	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EML4_RS08675	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
EML4_RS08680	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EML4_RS08690	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EML4_RS08695	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
EML4_RS08700	ENOG4108UFP	Essential cell division protein (By similarity)
EML4_RS08705	ENOG4105CPF	Cell wall formation (By similarity)
EML4_RS08710	ENOG4105CSH	Transporter
EML4_RS08715	ENOG4105BZU	Histidine kinase
EML4_RS08720	ENOG4105D4A	Cell wall formation (By similarity)
EML4_RS08725	ENOG4105DFU	Cell wall formation (By similarity)
EML4_RS08730	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EML4_RS08740	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
EML4_RS08745	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
EML4_RS08755	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
EML4_RS08770	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EML4_RS08775	ENOG4107YUR	Cell division protein mraZ
EML4_RS08800	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
EML4_RS08830	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
EML4_RS08845	ENOG4105SYT	Methylenetetrahydrofolate reductase
EML4_RS08850	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EML4_RS08860	ENOG4105E5G	Alpha beta hydrolase fold
EML4_RS08865	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
EML4_RS08895	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
EML4_RS08900	ENOG4105EQ0	Major Facilitator superfamily
EML4_RS08935	ENOG4105C26	Dehydrogenase
EML4_RS08940	ENOG4105C5F	glutamine synthetase
EML4_RS08945	ENOG4105CUB	amino acid
EML4_RS08960	ENOG4107FKK	extracellular solute-binding protein family 1
EML4_RS08975	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS09000	ENOG4105C3R	Methionine synthase
EML4_RS09005	ENOG4107QKS	N-acylglucosamine 2-epimerase
EML4_RS09035	ENOG4105MPN	Membrane
EML4_RS09050	ENOG4105BZU	Histidine kinase
EML4_RS09060	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EML4_RS09065	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EML4_RS09085	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
EML4_RS09090	ENOG4107QI1	Mate efflux family protein
EML4_RS09095	ENOG4105C8Q	Methyl-accepting chemotaxis
EML4_RS09105	ENOG4105CGZ	zinc metallopeptidase
EML4_RS09120	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EML4_RS09130	ENOG4105BZU	Histidine kinase
EML4_RS09145	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EML4_RS09155	ENOG4105F7P	transcriptional regulator AsnC family
EML4_RS09160	ENOG4105C3M	thioredoxin reductase
EML4_RS09165	ENOG4105CBN	LysR family transcriptional regulator
EML4_RS09175	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EML4_RS09210	ENOG4108KMM	Diguanylate cyclase
EML4_RS09230	ENOG4105C5X	domain protein
EML4_RS09240	ENOG41090HR	transcriptional regulator
EML4_RS09245	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EML4_RS09250	ENOG4105E0F	Histidine kinase
EML4_RS09255	ENOG4108Z7R	Chaperone CsaA
EML4_RS09260	ENOG4105II7	pyrroline-5-carboxylate reductase
EML4_RS09275	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
EML4_RS09285	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
EML4_RS09300	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EML4_RS09310	ENOG4107G9V	glycosyl transferase, family 39
EML4_RS09330	ENOG4105C26	Dehydrogenase
EML4_RS09335	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
EML4_RS09340	ENOG4105BZU	Histidine kinase
EML4_RS09345	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
EML4_RS09360	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EML4_RS09370	ENOG4105M74	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
EML4_RS09375	ENOG4105C3G	gtp-binding protein
EML4_RS09395	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EML4_RS09405	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EML4_RS09415	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EML4_RS09425	ENOG4105BZ1	(ABC) transporter
EML4_RS09430	ENOG4105BZ1	(ABC) transporter
EML4_RS09440	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
EML4_RS09445	ENOG4105EAM	Na Pi-cotransporter
EML4_RS09455	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
EML4_RS09470	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EML4_RS09475	ENOG4105P8F	nudix hydrolase
EML4_RS09485	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EML4_RS09505	ENOG4105VEV	-acetyltransferase
EML4_RS09520	ENOG41079KZ	Major Facilitator Superfamily
EML4_RS09530	ENOG4105CHF	Glutathione S-transferase
EML4_RS09535	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EML4_RS09545	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EML4_RS09550	ENOG4105DKK	Benzoate
EML4_RS09575	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EML4_RS09590	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
EML4_RS09615	ENOG41080HT	Transcriptional regulator, arsr family
EML4_RS09620	ENOG4108IJ7	Glycine betaine
EML4_RS09640	ENOG4107104	thymidine kinase
EML4_RS09675	ENOG4105CRQ	synthase (Component I)
EML4_RS09685	ENOG4105CPI	Metal Dependent Phosphohydrolase
EML4_RS09690	ENOG4105CPN	adenine deaminase
EML4_RS09700	ENOG4105CG3	alpha amylase, catalytic region
EML4_RS09705	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
EML4_RS09725	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
EML4_RS09755	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EML4_RS09775	ENOG4105C7W	Xanthine dehydrogenase
EML4_RS09785	ENOG4105ETT	transcriptional Regulator, LysR family
EML4_RS09800	ENOG4107QUY	Guanine deaminase
EML4_RS09810	ENOG4105DMF	Dehydrogenase
EML4_RS09820	ENOG4108RZE	Tetr family transcriptional regulator
EML4_RS09825	ENOG4105DZ1	carboxypeptidase
EML4_RS09840	ENOG4108Z2U	ureidoglycolate hydrolase
EML4_RS09855	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
EML4_RS09865	ENOG4108TXN	phosphonate metabolism protein
EML4_RS09870	ENOG41087SS	fad dependent oxidoreductase
EML4_RS09875	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
EML4_RS09880	ENOG4105BZU	Histidine kinase
EML4_RS09885	ENOG4105C1J	atp-dependent rna helicase
EML4_RS09895	ENOG4105EQR	Transposase IS116 IS110 IS902
EML4_RS09900	ENOG4105MGM	doxx family
EML4_RS09905	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
EML4_RS09955	ENOG4108HWW	ABC transporter
EML4_RS09960	ENOG4105C2J	ABC transporter
EML4_RS09965	ENOG4105DFW	ABC transporter
EML4_RS10095	ENOG4105C3R	Methionine synthase
EML4_RS10105	ENOG4105DSP	amino acid AbC transporter
EML4_RS10115	ENOG4108JEH	abc transporter atp-binding protein
EML4_RS10195	ENOG4108R86	Transcriptional regulator
EML4_RS10200	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
EML4_RS10205	ENOG4105CD3	dihydroorotase
EML4_RS10210	ENOG4105M6F	mutator MutT protein
EML4_RS10220	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
EML4_RS10225	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
EML4_RS10255	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
EML4_RS10260	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EML4_RS10265	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
EML4_RS10280	ENOG4105CQM	Urea amidohydrolase subunit alpha
EML4_RS10285	ENOG4106ISJ	urease accessory protein
EML4_RS10300	ENOG4105KI2	Urea amidohydrolase subunit beta
EML4_RS10305	ENOG4105XDF	Protein of unknown function (DUF1272)
EML4_RS10310	ENOG4108YZ9	Urea amidohydrolase subunit gamma
EML4_RS10315	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EML4_RS10325	ENOG4108IV0	ABC, transporter
EML4_RS10335	ENOG4105C0Z	ABC transporter
EML4_RS10345	ENOG4105C32	Amino acid ABC transporter (Permease)
EML4_RS10360	ENOG4107R5B	glutamine synthetase
EML4_RS10365	ENOG4105CHR	reductase
EML4_RS10370	ENOG4105BZU	Histidine kinase
EML4_RS10375	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EML4_RS10385	ENOG4108ZJ4	polysaccharide deacetylase
EML4_RS10400	ENOG4108IV0	ABC, transporter
EML4_RS10405	ENOG4105C0Z	ABC transporter
EML4_RS10410	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
EML4_RS10420	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
EML4_RS10505	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EML4_RS10515	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EML4_RS10540	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
EML4_RS10550	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
EML4_RS10555	ENOG4107XDR	Lactoylglutathione lyase
EML4_RS10560	ENOG4105WD1	Membrane
EML4_RS10565	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS10570	ENOG4105EHG	Permease protein
EML4_RS10575	ENOG4107R4I	Periplasmic binding protein
EML4_RS10585	ENOG41090JE	Utilization Protein
EML4_RS10600	ENOG4105VMP	Transcriptional regulator
EML4_RS10615	ENOG4105VUH	addiction module killer protein
EML4_RS10625	ENOG41062D9	Histidine kinase
EML4_RS10670	ENOG4105DHS	permease protein
EML4_RS10675	ENOG4105CM4	permease protein
EML4_RS10680	ENOG4108IPW	abc transporter atp-binding protein
EML4_RS10685	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
EML4_RS10705	ENOG4105CV8	reductase
EML4_RS10710	ENOG4105F27	Major Facilitator
EML4_RS10715	ENOG4105EXG	Transcriptional regulator
EML4_RS10720	ENOG4105CC0	LysR family Transcriptional regulator
EML4_RS10730	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
EML4_RS10750	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
EML4_RS10755	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
EML4_RS10760	ENOG4107B2H	carbonic anhydrase
EML4_RS10770	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EML4_RS10785	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EML4_RS10790	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EML4_RS10795	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
EML4_RS10800	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
EML4_RS10805	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
EML4_RS10810	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
EML4_RS10815	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
EML4_RS10820	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
EML4_RS10825	ENOG4108YNN	Heme oxygenase
EML4_RS10830	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EML4_RS10850	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
EML4_RS10860	ENOG4108MGF	sugar kinase
EML4_RS10870	ENOG4105F0I	Aminotransferase
EML4_RS10875	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
EML4_RS10885	ENOG4108JQ7	(ABC) transporter
EML4_RS10895	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS10900	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS10905	ENOG4108J59	Extracellular solute-binding protein, family 5
EML4_RS10910	ENOG4108IGT	Dipeptidase
EML4_RS10955	ENOG4105KHM	amidohydrolase 2
EML4_RS10960	ENOG4108KC1	acyl-Coa dehydrogenase
EML4_RS10990	ENOG4105ETX	regulatoR
EML4_RS11005	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS11010	ENOG4107RCV	ABC transporter, permease
EML4_RS11015	ENOG4105C4Y	ABC transporter
EML4_RS11020	ENOG4105C4Y	ABC transporter
EML4_RS11025	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EML4_RS11095	ENOG4105C8V	SAICAR synthetase
EML4_RS11105	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EML4_RS11110	ENOG4105BZS	acriflavin resistance protein
EML4_RS11120	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EML4_RS11125	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
EML4_RS11145	ENOG4105CBN	LysR family transcriptional regulator
EML4_RS11150	ENOG4105CJP	fad dependent oxidoreductase
EML4_RS11155	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
EML4_RS11160	ENOG4105E0C	molybdate abc transporter
EML4_RS11165	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS11180	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
EML4_RS11195	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
EML4_RS11200	ENOG410609C	Acyl carrier protein
EML4_RS11230	ENOG4105BZ1	(ABC) transporter
EML4_RS11235	ENOG4105IJJ	transcriptional regulator, crp fnr family
EML4_RS11255	ENOG4107QQG	Dehydrogenase
EML4_RS11280	ENOG4107QSI	ABC, transporter
EML4_RS11285	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS11290	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS11305	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EML4_RS11310	ENOG4106N3A	copper homeostasis protein cutc
EML4_RS11315	ENOG4105S8Q	sugar efflux transporter
EML4_RS11325	ENOG4105E2D	ec 3.2.1.52
EML4_RS11330	ENOG4108KEZ	Dehydrogenase
EML4_RS11335	ENOG4106KNT	transcriptional regulator
EML4_RS11345	ENOG4108IJ9	(ABC) transporter
EML4_RS11355	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
EML4_RS11380	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EML4_RS11385	ENOG4105CE4	GlcNAc 6-P deacetylase
EML4_RS11390	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
EML4_RS11400	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
EML4_RS11405	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
EML4_RS11410	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EML4_RS11420	ENOG4105CFU	surface antigen
EML4_RS11430	ENOG4108V3W	Chemotaxis protein, CheW
EML4_RS11435	ENOG4107SDU	Methyl-accepting chemotaxis
EML4_RS11440	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EML4_RS11445	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EML4_RS11450	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EML4_RS11455	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EML4_RS11460	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
EML4_RS11465	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EML4_RS11475	ENOG4105C25	Primosomal protein n'
EML4_RS11480	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EML4_RS11500	ENOG4107QN2	dihydrolipoyl dehydrogenase
EML4_RS11505	ENOG4105N14	lysine exporter protein LysE YggA
EML4_RS11515	ENOG4105C7S	Dehydrogenase
EML4_RS11520	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
EML4_RS11525	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
EML4_RS11530	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
EML4_RS11535	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EML4_RS11540	ENOG4105D6Z	AFG1 family ATPase
EML4_RS11545	ENOG4105YU5	Outer membrane lipoprotein
EML4_RS11550	ENOG4105E33	succinate dehydrogenase
EML4_RS11555	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
EML4_RS11565	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
EML4_RS11575	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EML4_RS11590	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EML4_RS11595	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EML4_RS11600	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
EML4_RS11625	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
EML4_RS11640	ENOG410856B	UPF0235 protein
EML4_RS11645	ENOG4105F0N	pyrophosphate phospho-hydrolase
EML4_RS11655	ENOG4105CI3	gtp-binding protein typa
EML4_RS11660	ENOG4105DGW	oligopeptidase A
EML4_RS11665	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
EML4_RS11675	ENOG4105CDH	Citrulline--aspartate ligase
EML4_RS11685	ENOG410829K	Lysine exporter protein (Lyse ygga)
EML4_RS11695	ENOG4105C7J	ABC transporter, permease
EML4_RS11705	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EML4_RS11720	ENOG4105KZX	Pterin carbinolamine dehydratase
EML4_RS11730	ENOG4105M7V	2'-5' rna ligase
EML4_RS11740	ENOG4108I0Y	(ABC) transporter
EML4_RS11750	ENOG4105HFZ	Membrane
EML4_RS11765	ENOG4107QM5	aconitate hydratase
EML4_RS11770	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
EML4_RS11775	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
EML4_RS11780	ENOG41060IM	Heme exporter protein
EML4_RS11795	ENOG4106TD9	Diguanylate cyclase
EML4_RS11800	ENOG4108VRQ	UPF0314 protein
EML4_RS11805	ENOG4107835	probably involved in intracellular septation (By similarity)
EML4_RS11810	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EML4_RS11815	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EML4_RS11820	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
EML4_RS11835	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EML4_RS11840	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
EML4_RS11845	ENOG4105K5M	30s ribosomal protein S16
EML4_RS11850	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
EML4_RS11855	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
EML4_RS11865	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
EML4_RS11890	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EML4_RS11905	ENOG4105ERG	peptidase m48, ste24p
EML4_RS11910	ENOG4107T0D	ABC, transporter
EML4_RS11930	ENOG4105C5H	ABC transporter
EML4_RS11940	ENOG4105CVG	Homoserine O-transsuccinylase
EML4_RS11945	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
EML4_RS11950	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
EML4_RS11955	ENOG4105CTB	Polyprenyl synthetase
EML4_RS11960	ENOG4108ZG0	Ompa motb domain protein
EML4_RS11965	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
EML4_RS11970	ENOG4106UW1	Major Facilitator superfamily
EML4_RS11975	ENOG4105MVE	transcriptional regulator
EML4_RS11980	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
EML4_RS11985	ENOG4105WH1	Two component transcriptional regulator luxr family
EML4_RS11990	ENOG4105BZ1	(ABC) transporter
EML4_RS11995	ENOG4105E2V	Glycosyltransferase 36
EML4_RS12000	ENOG4105CH2	amidohydrolase
EML4_RS12010	ENOG4105D5U	fad dependent oxidoreductase
EML4_RS12025	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EML4_RS12030	ENOG4105EXW	epimerase dehydratase
EML4_RS12035	ENOG4105CQB	FAD linked oxidase domain protein
EML4_RS12040	ENOG4107YCY	Transcriptional regulator
EML4_RS12050	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
EML4_RS12055	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EML4_RS12060	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EML4_RS12065	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EML4_RS12075	ENOG4105DFA	alanine racemase domain protein
EML4_RS12080	ENOG4105C8T	Leucyl-tRNA synthetase
EML4_RS12095	ENOG4108Z4U	Ferredoxin
EML4_RS12100	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EML4_RS12120	ENOG4105C29	acyl-CoA thioesterase
EML4_RS12125	ENOG4108YZA	Nitrogen regulatory protein pii
EML4_RS12130	ENOG4105BZU	Histidine kinase
EML4_RS12135	ENOG4105CNU	cell division protein FtsK
EML4_RS12140	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
EML4_RS12155	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EML4_RS12165	ENOG4108VJ1	Transcriptional regulator (CarD family
EML4_RS12170	ENOG4105C7I	Dehydrogenase
EML4_RS12175	ENOG4105DEU	major facilitator superfamily
EML4_RS12190	ENOG4105CHR	reductase
EML4_RS12205	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EML4_RS12210	ENOG4105PXI	polysaccharide deacetylase
EML4_RS12215	ENOG4105CN1	protease
EML4_RS12225	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
EML4_RS12235	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
EML4_RS12240	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
EML4_RS12245	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
EML4_RS12250	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EML4_RS12265	ENOG4105K46	50S ribosomal protein l27
EML4_RS12270	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
EML4_RS12295	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EML4_RS12300	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EML4_RS12310	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
EML4_RS12320	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
EML4_RS12385	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
EML4_RS12395	ENOG4105EFT	decarboxylase
EML4_RS12400	ENOG4105DIA	mandelate racemase muconate lactonizing
EML4_RS12405	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
EML4_RS12410	ENOG4107QZW	Altronate oxidoreductase
EML4_RS12415	ENOG4105CPQ	Dehydrogenase
EML4_RS12435	ENOG4105CNN	ABC, transporter
EML4_RS12440	ENOG4105C2J	ABC transporter
EML4_RS12445	ENOG4107YCY	Transcriptional regulator
EML4_RS12450	ENOG4105CTX	dehydratase
EML4_RS12455	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EML4_RS12470	ENOG4105D0M	Protease HtpX homolog
EML4_RS12490	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
EML4_RS12495	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EML4_RS12500	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EML4_RS12505	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
EML4_RS12510	ENOG4108YXA	Membrane
EML4_RS12515	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
EML4_RS12520	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
EML4_RS12525	ENOG4108UHJ	MAF-like protein
EML4_RS12530	ENOG4105E2X	shikimate dehydrogenase
EML4_RS12535	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
EML4_RS12540	ENOG4107RZZ	dna polymerase iii epsilon subunit
EML4_RS12545	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
EML4_RS12550	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
EML4_RS12560	ENOG4105CA3	membrane-bound lytic murein transglycosylase
EML4_RS12585	ENOG4105ERH	Fumarylacetoacetate hydrolase
EML4_RS12600	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
EML4_RS12605	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EML4_RS12610	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
EML4_RS12615	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
EML4_RS12630	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
EML4_RS12640	ENOG4108S0S	Nucleotidyl transferase
EML4_RS12645	ENOG4105K8N	protein family UPF0079, ATPase
EML4_RS12650	ENOG4105I8F	Histidine kinase
EML4_RS12655	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
EML4_RS12660	ENOG41080Z8	PHOSPHOCARRIER protein
EML4_RS12665	ENOG4105DAS	pts system
EML4_RS12670	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
EML4_RS12675	ENOG4105EB3	Histidine kinase
EML4_RS12680	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EML4_RS12685	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
EML4_RS12690	ENOG4108YZN	class I peptide chain release factor
EML4_RS12695	ENOG4109066	lysm domain bon superfamily protein
EML4_RS12700	ENOG4105CS9	pantothenic acid kinase
EML4_RS12705	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
EML4_RS12710	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EML4_RS12715	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
EML4_RS12720	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
EML4_RS12730	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EML4_RS12735	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
EML4_RS12740	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
EML4_RS12750	ENOG4107QP3	malate synthase g
EML4_RS12765	ENOG4108UYB	regulatoR
EML4_RS12770	ENOG4105TX3	Histidine kinase
EML4_RS12775	ENOG4105CQ7	ATP-dependent helicase
EML4_RS12810	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EML4_RS12815	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
EML4_RS12820	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
EML4_RS12825	ENOG4105CNN	ABC, transporter
EML4_RS12830	ENOG4105C2J	ABC transporter
EML4_RS12835	ENOG4105CS9	pantothenic acid kinase
EML4_RS12840	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
EML4_RS12845	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
EML4_RS12865	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EML4_RS12905	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
EML4_RS12910	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EML4_RS12915	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EML4_RS12920	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EML4_RS12925	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
EML4_RS12930	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EML4_RS12945	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
EML4_RS12950	ENOG4107SFI	Major Facilitator superfamily
EML4_RS12955	ENOG4105CVE	Lytic murein transglycosylase
EML4_RS12960	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
EML4_RS12970	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
EML4_RS12975	ENOG4107QMP	dna polymerase iii subunits gamma and tau
EML4_RS12990	ENOG4105E09	nadh pyrophosphatase
EML4_RS12995	ENOG4105CQC	Prephenate dehydratase
EML4_RS13000	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
EML4_RS13005	ENOG4105G9V	cytochrome C
EML4_RS13015	ENOG4108JQC	penicillin-binding protein 1A
EML4_RS13020	ENOG4108UIN	ybak prolyl-trna synthetase associated region
EML4_RS13030	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EML4_RS13040	ENOG4105C2M	dna polymerase I
EML4_RS13045	ENOG41082R8	50S ribosomal protein l32
EML4_RS13050	ENOG4105CQZ	Histidine kinase
EML4_RS13055	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EML4_RS13075	ENOG41069P5	Protein slyX homolog
EML4_RS13085	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EML4_RS13090	ENOG4105CFG	Acts as a chaperone (By similarity)
EML4_RS13105	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EML4_RS13110	ENOG4105DIH	basic membrane
EML4_RS13115	ENOG4108JQ9	ABC transporter
EML4_RS13130	ENOG4105KG3	cytidine deaminase
EML4_RS13135	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
EML4_RS13140	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
EML4_RS13145	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
EML4_RS13155	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EML4_RS13160	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
EML4_RS13165	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
EML4_RS13175	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
EML4_RS13180	ENOG4105CCU	oxidase (Subunit III)
EML4_RS13185	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EML4_RS13190	ENOG4105E2S	oxidase) subunit II
EML4_RS13195	ENOG4105CSH	Transporter
EML4_RS13200	ENOG4105CBC	glutamate synthase
EML4_RS13205	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EML4_RS13220	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
EML4_RS13230	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
EML4_RS13240	ENOG4105EN6	Membrane
EML4_RS13260	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
EML4_RS13280	ENOG4108ZZF	transport protein (ExbD)
EML4_RS13290	ENOG4105DG4	malate L-lactate dehydrogenase
EML4_RS13305	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
EML4_RS13310	ENOG4105FD8	phosphonate metabolism protein PhnM
EML4_RS13315	ENOG4108TXN	phosphonate metabolism protein
EML4_RS13325	ENOG4105S7S	phosphonate abc transporter
EML4_RS13330	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
EML4_RS13335	ENOG4105D5T	phosphonate abc transporter
EML4_RS13345	ENOG4105HRV	phosphonate c-p lyase system protein phnl
EML4_RS13350	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
EML4_RS13380	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
EML4_RS13385	ENOG4105CHC	glucokinase (EC 2.7.1.2)
EML4_RS13390	ENOG4108Z5K	methylglyoxal synthase
EML4_RS13395	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
EML4_RS13405	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
EML4_RS13410	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
EML4_RS13415	ENOG4108JQ5	ABC transporter
EML4_RS13420	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EML4_RS13425	ENOG4105CFQ	glutamine synthetase
EML4_RS13430	ENOG4105CJP	fad dependent oxidoreductase
EML4_RS13435	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
EML4_RS13440	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
EML4_RS13445	ENOG4108IJ8	ABC transporter
EML4_RS13450	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
EML4_RS13455	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
EML4_RS13465	ENOG4105KPV	Transcriptional regulator
EML4_RS13475	ENOG4105D0M	Protease HtpX homolog
EML4_RS13480	ENOG4108M3P	Membrane
EML4_RS13485	ENOG4105C26	Dehydrogenase
EML4_RS13495	ENOG4105DFI	Membrane
EML4_RS13510	ENOG4107SN7	NLP P60 protein
EML4_RS13520	ENOG4107RH7	Nicotinate phosphoribosyltransferase
EML4_RS13525	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EML4_RS13600	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
EML4_RS13605	ENOG4105KWI	UPF0339 protein
EML4_RS13610	ENOG4108UQ1	hydrolase, family 25
EML4_RS13615	ENOG4105T38	integral membrane protein
EML4_RS13620	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EML4_RS13635	ENOG4105CAY	ferredoxin--nadp reductase
EML4_RS13650	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EML4_RS13685	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
EML4_RS13690	ENOG4105CH5	extracellular solute-binding protein, family 7
EML4_RS13715	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
EML4_RS13720	ENOG41082BR	50S ribosomal protein L35
EML4_RS13725	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
EML4_RS13735	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EML4_RS13740	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
EML4_RS13745	ENOG4105CPC	Aldo Keto reductase
EML4_RS13750	ENOG4105EQ2	LysR family Transcriptional regulator
EML4_RS13790	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EML4_RS13795	ENOG4105CXK	mandelate racemase muconate lactonizing
EML4_RS13805	ENOG4108ZT1	Transcriptional regulator
EML4_RS13810	ENOG4108KTG	Membrane protein, drug metabolite transporter
EML4_RS13815	ENOG4105C88	aminopeptidase
EML4_RS13820	ENOG4108Z66	YbaK ebsC protein
EML4_RS13825	ENOG4105KUZ	arsenate reductase
EML4_RS13845	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
EML4_RS13855	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EML4_RS13870	ENOG4105KAV	tspo and mbr like protein
EML4_RS13895	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EML4_RS13900	ENOG4105K6T	rare lipoprotein A
EML4_RS13910	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
EML4_RS13920	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EML4_RS13935	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
EML4_RS13945	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EML4_RS13955	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
EML4_RS13960	ENOG41082FP	UPF0102 protein
EML4_RS13985	ENOG4108IJ9	(ABC) transporter
EML4_RS13995	ENOG4105D7Z	glutathione synthase
EML4_RS14000	ENOG4105C0P	Mg chelatase subunit ChlI
EML4_RS14010	ENOG410829K	Lysine exporter protein (Lyse ygga)
EML4_RS14015	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
EML4_RS14020	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
EML4_RS14025	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
EML4_RS14040	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
EML4_RS14045	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EML4_RS14050	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
EML4_RS14055	ENOG4105E39	Enoyl-CoA hydratase
EML4_RS14060	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
EML4_RS14190	ENOG41090BB	DNA mismatch endonuclease (vsr)
EML4_RS14245	ENOG4105CS6	Rhs element vgr protein
EML4_RS14255	ENOG4106178	UPF0339 protein
EML4_RS14280	ENOG4105J7D	transcriptional regulator
EML4_RS14300	ENOG4105Y49	secretion protein, HlyD family
EML4_RS14315	ENOG4105D8X	mechanosensitive ion channel
EML4_RS14330	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
EML4_RS14340	ENOG4105CP9	extracellular ligand-binding receptor
EML4_RS14345	ENOG4105C32	Amino acid ABC transporter (Permease)
EML4_RS14355	ENOG4105C0Z	ABC transporter
EML4_RS14360	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS14370	ENOG4105C0A	alcohol dehydrogenase
EML4_RS14375	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS14380	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS14390	ENOG4108JQ7	(ABC) transporter
EML4_RS14395	ENOG4105E98	transcriptional regulator DeoR family
EML4_RS14400	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
EML4_RS14420	ENOG4105CPD	ethanolamine ammonia-lyase
EML4_RS14425	ENOG4107FQ9	ethanolamine ammonia-lyase
EML4_RS14430	ENOG4107SUZ	Sodium/hydrogen exchanger family
EML4_RS14435	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
EML4_RS14450	ENOG4105CJP	fad dependent oxidoreductase
EML4_RS14455	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS14465	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
EML4_RS14470	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EML4_RS14485	ENOG4108JQ6	ABC transporter
EML4_RS14495	ENOG4105BZU	Histidine kinase
EML4_RS14530	ENOG4105E0F	Histidine kinase
EML4_RS14535	ENOG4108ZHJ	Organic hydroperoxide resistance protein
EML4_RS14545	ENOG4105CIR	epoxide hydrolase
EML4_RS14570	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
EML4_RS14580	ENOG4108ZXC	Two component transcriptional regulator, luxr family
EML4_RS14585	ENOG4108ZXC	Two component transcriptional regulator, luxr family
EML4_RS14605	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
EML4_RS14610	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EML4_RS14625	ENOG4108FUF	Transcriptional regulator, IclR family
EML4_RS14640	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
EML4_RS14660	ENOG4105EW9	transcriptional regulator AsnC family
EML4_RS14665	ENOG4107SCK	Monooxygenase
EML4_RS14685	ENOG4105C2W	permease
EML4_RS14695	ENOG4105ETT	transcriptional Regulator, LysR family
EML4_RS14740	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
EML4_RS14745	ENOG4105F38	ABC transporter, permease
EML4_RS14755	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS14780	ENOG4107SDU	Methyl-accepting chemotaxis
EML4_RS14805	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
EML4_RS14810	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS14820	ENOG4105GVF	(ABC) transporter
EML4_RS14825	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
EML4_RS14830	ENOG4108SNK	aliphatic sulfonates import ATP-binding protein SsuB
EML4_RS14835	ENOG4105DRS	transport system, permease
EML4_RS14840	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
EML4_RS14870	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS14885	ENOG4108WBH	protein TIM barrel
EML4_RS14900	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS14905	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
EML4_RS14910	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
EML4_RS14915	ENOG4105BZ7	extracellular solute-binding protein family 1
EML4_RS14920	ENOG4108W9H	Tetr family transcriptional regulator
EML4_RS14940	ENOG4105DDC	Oxidoreductase domain protein
EML4_RS14960	ENOG4105K5G	30S ribosomal protein S21
EML4_RS14980	ENOG4105FAT	Acyl-transferase
EML4_RS14985	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EML4_RS14990	ENOG4107XII	Glycosyl Hydrolase Family 88
EML4_RS15010	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
EML4_RS15015	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
EML4_RS15025	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EML4_RS15035	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EML4_RS15040	ENOG4105GAK	amidohydrolase 2
EML4_RS15045	ENOG4105CXK	mandelate racemase muconate lactonizing
EML4_RS15050	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
EML4_RS15055	ENOG4105CHR	reductase
EML4_RS15060	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
EML4_RS15065	ENOG4105E9Z	Nad-dependent epimerase dehydratase
EML4_RS15070	ENOG4105JXH	GntR family transcriptional regulator
EML4_RS15085	ENOG4105CPC	Aldo Keto reductase
EML4_RS15115	ENOG41063TF	transcriptional regulator (AraC
EML4_RS15120	ENOG4105EU0	Major facilitator Superfamily
EML4_RS15125	ENOG4105W8I	Transcriptional regulator
EML4_RS15130	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EML4_RS15140	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EML4_RS15145	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EML4_RS15160	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS15165	ENOG4105CPQ	Dehydrogenase
EML4_RS15170	ENOG4105CHR	reductase
EML4_RS15180	ENOG4107UEK	pfkb domain protein
EML4_RS15185	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
EML4_RS15200	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS15210	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
EML4_RS15240	ENOG4105DSE	periplasmic solute binding protein
EML4_RS15245	ENOG4105CC5	ABC transporter
EML4_RS15250	ENOG4105DIK	(ABC) transporter
EML4_RS15255	ENOG4105CKI	cobalamin synthesis protein
EML4_RS15270	ENOG4105CKI	cobalamin synthesis protein
EML4_RS15275	ENOG4108IJG	ABC transporter substrate-binding protein
EML4_RS15280	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
EML4_RS15285	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
EML4_RS15290	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS15325	ENOG4105CC0	LysR family Transcriptional regulator
EML4_RS15330	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
EML4_RS15335	ENOG4105CNN	ABC, transporter
EML4_RS15350	ENOG4105BZS	acriflavin resistance protein
EML4_RS15355	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EML4_RS15360	ENOG4105BZU	Histidine kinase
EML4_RS15365	ENOG4105S0E	allantoin catabolism protein
EML4_RS15380	ENOG4105DG4	malate L-lactate dehydrogenase
EML4_RS15390	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS15415	ENOG4107STF	Involved in phosphonate degradation (By similarity)
EML4_RS15425	ENOG4108KB1	transcriptional regulator, arac family
EML4_RS15430	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
EML4_RS15445	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
EML4_RS15450	ENOG4105C2J	ABC transporter
EML4_RS15455	ENOG4107R9N	ABC transporter
EML4_RS15460	ENOG41062B0	ABC transporter, permease
EML4_RS15465	ENOG4107EJG	GntR family transcriptional regulator
EML4_RS15480	ENOG4107SWE	Methyltransferase
EML4_RS15485	ENOG4105C0B	DNA polymerase III (alpha subunit)
EML4_RS15530	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
EML4_RS15540	ENOG4105XN3	extracellular solute-binding protein family 1
EML4_RS15550	ENOG4105EPC	oxidoreductase
EML4_RS15580	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
EML4_RS15585	ENOG4107QMS	site-determining protein
EML4_RS15590	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
EML4_RS15595	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
EML4_RS15600	ENOG4107YCY	Transcriptional regulator
EML4_RS15605	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
EML4_RS15615	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EML4_RS15620	ENOG4105CPQ	Dehydrogenase
EML4_RS15625	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
EML4_RS15645	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EML4_RS15650	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EML4_RS15655	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
EML4_RS15670	ENOG4105CYM	Glutathione S-transferase
EML4_RS15675	ENOG4108JQ6	ABC transporter
EML4_RS15680	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
EML4_RS15695	ENOG41069H0	dihydroorotase EC 3.5.2.3
EML4_RS15710	ENOG4106R87	Extracellular solute-binding protein, family 5
EML4_RS15715	ENOG4105JNK	Glycosyl transferase (Group 1
EML4_RS15755	ENOG4107QM2	Aldo Keto reductase
EML4_RS15775	ENOG4108M8H	domain protein
EML4_RS15790	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS15795	ENOG4107T3P	ABC, transporter
EML4_RS15800	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
EML4_RS15810	ENOG4105CJQ	hydrolase, family 31
EML4_RS15820	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
EML4_RS15825	ENOG4107Z6I	Thiamine biosynthesis protein
EML4_RS15830	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
EML4_RS15835	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
EML4_RS15850	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EML4_RS15855	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EML4_RS15880	ENOG4105CK2	sodium dicarboxylate symporter
EML4_RS15890	ENOG4106PGW	Short-chain dehydrogenase reductase Sdr
EML4_RS15910	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
EML4_RS15920	ENOG4107QZ7	Cellulose synthase catalytic subunit
EML4_RS15930	ENOG4107SZR	mannose-6-phosphate isomerase
EML4_RS15950	ENOG4105CMR	udp-glucose 4-epimerase
EML4_RS15955	ENOG4108IAJ	Nad-dependent epimerase dehydratase
EML4_RS15965	ENOG4105WH1	Two component transcriptional regulator luxr family
EML4_RS15980	ENOG4108JJ6	Type I secretion system ATPase
EML4_RS15985	ENOG4107QZV	Type I secretion membrane fusion protein
EML4_RS16015	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EML4_RS16025	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
EML4_RS16035	ENOG4105CHR	reductase
EML4_RS16045	ENOG4108VX5	3-methyladenine DNA glycosylase
EML4_RS16060	ENOG4105FKQ	transcriptional regulator
EML4_RS16065	ENOG4107T3P	ABC, transporter
EML4_RS16080	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS16090	ENOG4107RJ5	oxidoreductase
EML4_RS16095	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
EML4_RS16100	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
EML4_RS16105	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EML4_RS16115	ENOG4105D9R	oxidoreductase
EML4_RS16130	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
EML4_RS16160	ENOG4106NZI	LysR family Transcriptional regulator
EML4_RS16165	ENOG4105C6K	Malic enzyme
EML4_RS16180	ENOG4105DRP	amino acid AbC transporter
EML4_RS16185	ENOG4105CDA	abc transporter atp-binding protein
EML4_RS16190	ENOG4108PGP	mmge prpd family protein
EML4_RS16200	ENOG4107SDU	Methyl-accepting chemotaxis
EML4_RS16205	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EML4_RS16220	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
EML4_RS16225	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EML4_RS16230	ENOG4105CH5	extracellular solute-binding protein, family 7
EML4_RS16235	ENOG4108Z86	Glutamine amidotransferase
EML4_RS16240	ENOG4105CNN	ABC, transporter
EML4_RS16245	ENOG4105C2J	ABC transporter
EML4_RS16260	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
EML4_RS16265	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS16280	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS16290	ENOG4105GZI	Transcriptional regulator
EML4_RS16295	ENOG4105D44	asparaginase
EML4_RS16310	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS16325	ENOG4108JQ6	ABC transporter
EML4_RS16330	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS16335	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS16340	ENOG4108S01	response regulator
EML4_RS16345	ENOG4105JSC	dimethylmenaquinone methyltransferase
EML4_RS16350	ENOG4105E9Z	Nad-dependent epimerase dehydratase
EML4_RS16365	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
EML4_RS16370	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
EML4_RS16380	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EML4_RS16385	ENOG4105D9R	oxidoreductase
EML4_RS16430	ENOG4108KPJ	rna polymerase sigma factor
EML4_RS16435	ENOG4105E0A	ABC, transporter
EML4_RS16440	ENOG4105EHG	Permease protein
EML4_RS16455	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EML4_RS16465	ENOG4105E0A	ABC, transporter
EML4_RS16470	ENOG4105EHG	Permease protein
EML4_RS16515	ENOG4105C26	Dehydrogenase
EML4_RS16520	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EML4_RS16525	ENOG4105C26	Dehydrogenase
EML4_RS16530	ENOG4105CJP	fad dependent oxidoreductase
EML4_RS16545	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EML4_RS16565	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS16570	ENOG4108JQ6	ABC transporter
EML4_RS16575	ENOG4108RYR	transcriptional regulator AsnC family
EML4_RS16580	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EML4_RS16595	ENOG41065RR	hydrogen cyanide synthase HcnA
EML4_RS16600	ENOG4105RQF	LysR family Transcriptional regulator
EML4_RS16610	ENOG4105EAB	amino acid AbC transporter
EML4_RS16615	ENOG4105CDA	abc transporter atp-binding protein
EML4_RS16625	ENOG4105CH2	amidohydrolase
EML4_RS16635	ENOG4105DEN	Luciferase family
EML4_RS16640	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
EML4_RS16650	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
EML4_RS16655	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
EML4_RS16670	ENOG4105KHC	sulfurtransferase
EML4_RS16685	ENOG4105C1G	acyl-Coa dehydrogenase
EML4_RS16695	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS16720	ENOG4105CPC	Aldo Keto reductase
EML4_RS16730	ENOG4105ETT	transcriptional Regulator, LysR family
EML4_RS16740	ENOG4105E43	Extracellular solute-binding protein, family 5
EML4_RS16755	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS16760	ENOG4105CH2	amidohydrolase
EML4_RS16765	ENOG4105FBW	Monooxygenase
EML4_RS16785	ENOG4108M8W	Monooxygenase
EML4_RS16790	ENOG4105DIA	mandelate racemase muconate lactonizing
EML4_RS16800	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS16805	ENOG4108JQ7	(ABC) transporter
EML4_RS16810	ENOG4105C3U	ABC transporter
EML4_RS16820	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS16830	ENOG4105JXH	GntR family transcriptional regulator
EML4_RS16845	ENOG4108UU4	oxidoreductase (Short chain dehydrogenase reductase family)
EML4_RS16855	ENOG4107S76	domain protein
EML4_RS16860	ENOG41080HT	Transcriptional regulator, arsr family
EML4_RS16870	ENOG4105KFG	YeeE YedE family protein
EML4_RS16875	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EML4_RS16880	ENOG4107QSN	dihydrolipoamide acetyltransferase
EML4_RS16885	ENOG4105CPP	Dehydrogenase, E1 component
EML4_RS16890	ENOG4107R0V	Pyruvate dehydrogenase
EML4_RS16895	ENOG4105C1G	acyl-Coa dehydrogenase
EML4_RS16900	ENOG4105CHU	acetyl-coa acetyltransferase
EML4_RS16905	ENOG4105J0Q	Transcriptional regulator
EML4_RS16910	ENOG4105C1G	acyl-Coa dehydrogenase
EML4_RS16915	ENOG4107QX3	carboxylase
EML4_RS16925	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
EML4_RS16935	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
EML4_RS16940	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
EML4_RS16945	ENOG4105C9F	isomerase
EML4_RS16955	ENOG4105E98	transcriptional regulator DeoR family
EML4_RS16965	ENOG4105C2J	ABC transporter
EML4_RS16970	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
EML4_RS16975	ENOG4105F5R	ABC transporter
EML4_RS16980	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
EML4_RS16995	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EML4_RS17015	ENOG4105F1N	DNA alkylation repair
EML4_RS17020	ENOG4108IJ6	ABC transporter
EML4_RS17025	ENOG4105ECW	sulfate abc transporter
EML4_RS17030	ENOG4108I5D	sulfate abc transporter
EML4_RS17035	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
EML4_RS17040	ENOG4108IPT	Naphthoate synthase
EML4_RS17055	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EML4_RS17070	ENOG4105VW4	glutaredoxin 3
EML4_RS17075	ENOG41081UC	Inherit from COG: Competence protein
EML4_RS17080	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
EML4_RS17095	ENOG4105M6F	mutator MutT protein
EML4_RS17105	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
EML4_RS17110	ENOG4105EIN	peptidylprolyl cis-trans isomerase
EML4_RS17115	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EML4_RS17120	ENOG4105FDR	Membrane
EML4_RS17230	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EML4_RS17235	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EML4_RS17250	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EML4_RS17275	ENOG4105EG2	ABC transporter, permease
EML4_RS17330	ENOG4108WRK	Transcriptional regulator
EML4_RS17340	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
EML4_RS17345	ENOG4105C2J	ABC transporter
EML4_RS17350	ENOG4108HWW	ABC transporter
EML4_RS17355	ENOG4105DFW	ABC transporter
EML4_RS17365	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
EML4_RS17395	ENOG4105CYM	Glutathione S-transferase
EML4_RS17400	ENOG4107QX3	carboxylase
EML4_RS17405	ENOG4105CFF	transcriptional regulator
EML4_RS17415	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
EML4_RS17425	ENOG4105E1F	short-chain dehydrogenase reductase
EML4_RS17435	ENOG4108WBT	adenosyltransferase
EML4_RS17445	ENOG4105BZJ	Electron transfer flavoprotein
EML4_RS17450	ENOG4105C10	Electron transfer flavoprotein
EML4_RS17455	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EML4_RS17465	ENOG4107ZT5	Thiol disulfide interchange protein
EML4_RS17470	ENOG4105CH7	arginosuccinase
EML4_RS17480	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
EML4_RS17495	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
EML4_RS17505	ENOG4105CAK	Cell division ATP-binding protein ftsE
EML4_RS17525	ENOG4108NH8	Cation transport protein
EML4_RS17540	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EML4_RS17545	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EML4_RS17550	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EML4_RS17570	ENOG4105KDC	50s ribosomal protein l28
EML4_RS17575	ENOG4105EX9	Membrane
EML4_RS17615	ENOG4105D49	3-dehydroquinate synthase
EML4_RS17620	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
EML4_RS17630	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EML4_RS17635	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
EML4_RS17640	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
EML4_RS17645	ENOG4105VFE	sira family
EML4_RS17650	ENOG4105CKI	cobalamin synthesis protein
EML4_RS17655	ENOG4105DZ1	carboxypeptidase
EML4_RS17670	ENOG4108JQB	penicillin-binding protein 1C
EML4_RS17675	ENOG4105DN3	alpha-2-macroglobulin domain protein
EML4_RS17680	ENOG4105W49	UPF0434 protein
EML4_RS17690	ENOG4105K63	Thioredoxin
EML4_RS17715	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EML4_RS17730	ENOG4108JQ1	Dehydrogenase
EML4_RS17745	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EML4_RS17750	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EML4_RS17755	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
EML4_RS17765	ENOG4105KCK	Peptidoglycan-associated lipoprotein
EML4_RS17770	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
EML4_RS17780	ENOG4105SG9	biopolymer transport protein, ExbD
EML4_RS17785	ENOG4105E02	MotA TolQ exbB proton channel
EML4_RS17790	ENOG4107YD3	Thioesterase
EML4_RS17800	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EML4_RS17815	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
EML4_RS17820	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
EML4_RS17825	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
EML4_RS17835	ENOG4105DEN	Luciferase family
EML4_RS17840	ENOG4105CDY	transcriptional regulatory protein
EML4_RS17855	ENOG4105D48	metallophosphoesterase
EML4_RS17900	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
EML4_RS17905	ENOG4105BZA	Phosphoglycerate kinase
EML4_RS17910	ENOG4107R1Y	fructose-bisphosphate aldolase
EML4_RS17935	ENOG41082FS	50S ribosomal protein L31
EML4_RS17940	ENOG4105BZ1	(ABC) transporter
EML4_RS17950	ENOG4105UYK	outer membrane protein a
EML4_RS17960	ENOG4105ECY	inositol monophosphatase
EML4_RS17995	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EML4_RS18005	ENOG4105M0T	TPR Repeat-Containing Protein
EML4_RS18010	ENOG4105Y2X	UPF0335 protein
EML4_RS18030	ENOG4105CA9	Pyruvate kinase
EML4_RS18035	ENOG4105EAQ	(twin-arginine translocation) pathway signal
EML4_RS18040	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EML4_RS18045	ENOG4105DPN	Oligoendopeptidase f
EML4_RS18050	ENOG4107Z5F	Aminotransferase class IV
EML4_RS18060	ENOG4105FE5	Homospermidine synthase
EML4_RS18065	ENOG4105ZWB	Outer membrane lipoprotein
EML4_RS18070	ENOG4105CGH	5'-nucleotidase
EML4_RS18075	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
EML4_RS18080	ENOG4107QX8	SPFH domain, Band 7 family protein
EML4_RS18090	ENOG4105C2X	Arabinose 5-phosphate isomerase
EML4_RS18115	ENOG4105CVE	Lytic murein transglycosylase
EML4_RS18130	ENOG4106F60	Histidine kinase
EML4_RS18150	ENOG4105C5W	Aldolase
EML4_RS18160	ENOG4105C08	Histidine kinase
EML4_RS18165	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
EML4_RS18170	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
EML4_RS18180	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
EML4_RS18190	ENOG4105HDK	L-asparaginase
EML4_RS18200	ENOG4108IJ0	Aspartate ammonia-lyase
EML4_RS18205	ENOG41073TP	transcriptional regulator
EML4_RS18210	ENOG4105BZS	acriflavin resistance protein
EML4_RS18220	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EML4_RS18225	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
EML4_RS18230	ENOG4105CZE	histidine utilization repressor
EML4_RS18245	ENOG4108HQS	Glycine betaine
EML4_RS18250	ENOG4108IJ7	Glycine betaine
EML4_RS18255	ENOG4105C84	Histidine ammonia-lyase
EML4_RS18270	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EML4_RS18275	ENOG4108JQ6	ABC transporter
EML4_RS18280	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS18290	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS18305	ENOG4105C0A	alcohol dehydrogenase
EML4_RS18325	ENOG4105NAU	thioesterase Superfamily protein
EML4_RS18345	ENOG4105NPQ	Pfam:DUF403
EML4_RS18360	ENOG4105C5H	ABC transporter
EML4_RS18365	ENOG4105C5I	Dehydrogenase
EML4_RS18370	ENOG4105C6F	GntR Family Transcriptional Regulator
EML4_RS18390	ENOG4105DRS	transport system, permease
EML4_RS18395	ENOG4105EP8	Glycosyl Hydrolase Family 88
EML4_RS18400	ENOG4108IJ9	(ABC) transporter
EML4_RS18440	ENOG4105CPQ	Dehydrogenase
EML4_RS18445	ENOG4105JSC	dimethylmenaquinone methyltransferase
EML4_RS18450	ENOG4107R0W	ABC transporter
EML4_RS18460	ENOG4105DRP	amino acid AbC transporter
EML4_RS18465	ENOG4105DRP	amino acid AbC transporter
EML4_RS18475	ENOG4105C5I	Dehydrogenase
EML4_RS18480	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
EML4_RS18485	ENOG4105EXW	epimerase dehydratase
EML4_RS18500	ENOG4105JSC	dimethylmenaquinone methyltransferase
EML4_RS18505	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
EML4_RS18520	ENOG4105DFI	Membrane
EML4_RS18525	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EML4_RS18530	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EML4_RS18540	ENOG4105P4J	Allophanate hydrolase, subunit 1
EML4_RS18545	ENOG4107R7A	Allophanate hydrolase subunit 2
EML4_RS18550	ENOG4105E7W	lamb ycsf family protein
EML4_RS18555	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS18565	ENOG4108I5D	sulfate abc transporter
EML4_RS18590	ENOG4105C8Q	Methyl-accepting chemotaxis
EML4_RS18595	ENOG4105CMG	Carbohydrate kinase
EML4_RS18600	ENOG41061GT	Aldolase
EML4_RS18610	ENOG4108FN7	Aldo keto reductase
EML4_RS18620	ENOG4105CNN	ABC, transporter
EML4_RS18625	ENOG4105C2J	ABC transporter
EML4_RS18665	ENOG4108ZNX	Heat shock protein
EML4_RS18670	ENOG4105DHU	Bile acid
EML4_RS18680	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EML4_RS18710	ENOG4108IJ9	(ABC) transporter
EML4_RS18715	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
EML4_RS18720	ENOG4105E98	transcriptional regulator DeoR family
EML4_RS18725	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EML4_RS18740	ENOG4108IFG	nitrite reductase, (NAD(P)H)
EML4_RS18745	ENOG4105D7T	ABC transporter
EML4_RS18770	ENOG4105DRR	Transcriptional regulator, GntR family
EML4_RS18775	ENOG4105C5A	transporter
EML4_RS18780	ENOG4105E7W	lamb ycsf family protein
EML4_RS18785	ENOG4105CFM	UPF0317 protein
EML4_RS18790	ENOG4105P4J	Allophanate hydrolase, subunit 1
EML4_RS18795	ENOG4108JIK	carboxylase
EML4_RS18800	ENOG4105E5K	Alpha-amylase
EML4_RS18805	ENOG4108Z4X	TRANSCRIPTIONal
EML4_RS18810	ENOG4105D05	Receptor
EML4_RS18815	ENOG4107QYG	anthranilate phosphoribosyltransferase
EML4_RS18855	ENOG4105KME	endoribonuclease L-psp
EML4_RS18870	ENOG41090B9	response to stress
EML4_RS18875	ENOG4105CGP	Urocanate hydratase
EML4_RS18885	ENOG4105C84	Histidine ammonia-lyase
EML4_RS18890	ENOG4105CI2	imidazolone-5-propionate hydrolase
EML4_RS18895	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EML4_RS18935	ENOG4108JQ5	ABC transporter
EML4_RS18940	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS18945	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS18950	ENOG4108J59	Extracellular solute-binding protein, family 5
EML4_RS18955	ENOG4105DRS	transport system, permease
EML4_RS18970	ENOG4105Y49	secretion protein, HlyD family
EML4_RS18990	ENOG4105R1U	AraC Family Transcriptional Regulator
EML4_RS18995	ENOG4108IND	Tetr family transcriptional regulator
EML4_RS19000	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
EML4_RS19025	ENOG4108ZT1	Transcriptional regulator
EML4_RS19030	ENOG4105F04	LysR family Transcriptional regulator
EML4_RS19035	ENOG4105C7F	AcnD-accessory protein PrpF
EML4_RS19050	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
EML4_RS19075	ENOG4105W8I	Transcriptional regulator
EML4_RS19080	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
EML4_RS19095	ENOG4105EFZ	amidohydrolase
EML4_RS19115	ENOG4105CBN	LysR family transcriptional regulator
EML4_RS19120	ENOG4105C57	major facilitator superfamily
EML4_RS19135	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EML4_RS19140	ENOG4108QIF	Phosphoesterase, PA-phosphatase related
EML4_RS19185	ENOG4105K5X	acetyltransferase
EML4_RS19190	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
EML4_RS19195	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EML4_RS19200	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
EML4_RS19205	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EML4_RS19210	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EML4_RS19225	ENOG41066UZ	arginase EC 3.5.3.1
EML4_RS19235	ENOG4105DFI	Membrane
EML4_RS19260	ENOG4105CSH	Transporter
EML4_RS19265	ENOG4105ECM	Sensor protein basS pmrB
EML4_RS19270	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EML4_RS19275	ENOG4105DIJ	Phosphoethanolamine transferase
EML4_RS19285	ENOG4106NZI	LysR family Transcriptional regulator
EML4_RS19290	ENOG4105E0K	tonB-dependent siderophore receptor
EML4_RS19300	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
EML4_RS19305	ENOG4105E0A	ABC, transporter
EML4_RS19315	ENOG4105G9V	cytochrome C
EML4_RS19340	ENOG4105C2J	ABC transporter
EML4_RS19345	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
EML4_RS19350	ENOG4105BZU	Histidine kinase
EML4_RS19355	ENOG4105WH1	Two component transcriptional regulator luxr family
EML4_RS19375	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
EML4_RS19380	ENOG4105D3G	Pseudouridine synthase
EML4_RS19390	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EML4_RS19395	ENOG4108IJ7	Glycine betaine
EML4_RS19400	ENOG4108HQS	Glycine betaine
EML4_RS19420	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
EML4_RS19500	ENOG4105K5G	30S ribosomal protein S21
EML4_RS19505	ENOG4105DDR	sarcosine oxidase (Beta subunit)
EML4_RS19520	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EML4_RS19540	ENOG4108ESZ	Glycogen debranching enzyme
EML4_RS19545	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
EML4_RS19550	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
EML4_RS19555	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
EML4_RS19560	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
EML4_RS19565	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
EML4_RS19580	ENOG4108UYU	AsnC family transcriptional regulator
EML4_RS19590	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EML4_RS19595	ENOG4105CHR	reductase
EML4_RS19600	ENOG4105CPQ	Dehydrogenase
EML4_RS19610	ENOG4108JJ9	ABC, transporter
EML4_RS19615	ENOG4108JJ8	(ABC) transporter
EML4_RS19620	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EML4_RS19625	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EML4_RS19650	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
EML4_RS19655	ENOG4108IYU	L-aspartate oxidase
EML4_RS19660	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
EML4_RS19690	ENOG4105CAT	Cytidine monophosphate kinase
EML4_RS19695	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EML4_RS19735	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS19740	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS19745	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS19750	ENOG4105C3U	ABC transporter
EML4_RS19755	ENOG4108JQ7	(ABC) transporter
EML4_RS19760	ENOG4105DEI	Mannitol dehydrogenase
EML4_RS19770	ENOG4105DIA	mandelate racemase muconate lactonizing
EML4_RS19790	ENOG4105C0Z	ABC transporter
EML4_RS19795	ENOG4108IV0	ABC, transporter
EML4_RS19800	ENOG4105C32	Amino acid ABC transporter (Permease)
EML4_RS19805	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
EML4_RS19820	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EML4_RS19840	ENOG4105DZG	Dehydrogenase
EML4_RS19845	ENOG4108Z9Z	response to DNA damage stimulus
EML4_RS19875	ENOG4108Z0Z	intracellular protease Pfpi family
EML4_RS19895	ENOG4105D7Z	glutathione synthase
EML4_RS19900	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
EML4_RS19905	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
EML4_RS19920	ENOG4105CHF	Glutathione S-transferase
EML4_RS19925	ENOG4105ETT	transcriptional Regulator, LysR family
EML4_RS19930	ENOG4105C26	Dehydrogenase
EML4_RS19935	ENOG4105GVF	(ABC) transporter
EML4_RS19940	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
EML4_RS19945	ENOG4105E2Y	ABC, transporter
EML4_RS19955	ENOG4105EW9	transcriptional regulator AsnC family
EML4_RS19970	ENOG41074H6	response regulator
EML4_RS19980	ENOG410903D	sensor protein
EML4_RS20005	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
EML4_RS20020	ENOG4105CFH	Aspartokinase
EML4_RS20025	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
EML4_RS20030	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EML4_RS20035	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EML4_RS20045	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EML4_RS20050	ENOG4105E4C	Lytic transglycosylase catalytic
EML4_RS20090	ENOG4105X54	addiction module antidote protein
EML4_RS20120	ENOG4105CMT	Dihydroxyacetone kinase
EML4_RS20125	ENOG4105F7P	transcriptional regulator AsnC family
EML4_RS20130	ENOG4105C28	cystathionine
EML4_RS20145	ENOG4108UZX	fmn reductase
EML4_RS20155	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
EML4_RS20165	ENOG4108JQ5	ABC transporter
EML4_RS20170	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS20190	ENOG4105CQB	FAD linked oxidase domain protein
EML4_RS20210	ENOG4108DBC	nitroreductase
EML4_RS20230	ENOG4105C5Q	Transcriptional regulator
EML4_RS20240	ENOG4107U9B	transcriptional regulator
EML4_RS20255	ENOG4105JAB	phenazine biosynthesis protein, phzf family
EML4_RS20270	ENOG4105CC0	LysR family Transcriptional regulator
EML4_RS20280	ENOG4105JQN	Transcriptional regulator
EML4_RS20285	ENOG4105CHJ	isochorismatase hydrolase
EML4_RS20310	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS20315	ENOG4105F38	ABC transporter, permease
EML4_RS20320	ENOG4105D38	putrescine abc transporter
EML4_RS20325	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
EML4_RS20335	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EML4_RS20350	ENOG4105E0A	ABC, transporter
EML4_RS20355	ENOG4108IHU	transport system permease protein
EML4_RS20360	ENOG4105DQ5	transport system permease protein
EML4_RS20365	ENOG4108HUF	Transporter
EML4_RS20370	ENOG4107RBR	Receptor
EML4_RS20375	ENOG41090KN	UPF0303 protein
EML4_RS20380	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS20390	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
EML4_RS20395	ENOG41060WC	Enoyl-CoA hydratase
EML4_RS20405	ENOG4108JP0	extracellular solute-binding protein family 1
EML4_RS20420	ENOG4108IJ9	(ABC) transporter
EML4_RS20445	ENOG4105R2D	cytochrome C
EML4_RS20450	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
EML4_RS20455	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EML4_RS20460	ENOG4105CCU	oxidase (Subunit III)
EML4_RS20475	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
EML4_RS20490	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EML4_RS20500	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EML4_RS20520	ENOG4108IG5	Transcriptional regulator
EML4_RS20535	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EML4_RS20550	ENOG4105CPQ	Dehydrogenase
EML4_RS20560	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
EML4_RS20570	ENOG4105CNN	ABC, transporter
EML4_RS20580	ENOG4105EF1	ribulokinase
EML4_RS20590	ENOG4105CSH	Transporter
EML4_RS20620	ENOG4105UYK	outer membrane protein a
EML4_RS20675	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EML4_RS20695	ENOG4105CS6	Rhs element vgr protein
EML4_RS20715	ENOG4105BZU	Histidine kinase
EML4_RS20735	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS20740	ENOG4105EE5	Membrane protein terC
EML4_RS20760	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
EML4_RS20765	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
EML4_RS20770	ENOG4105BZ7	extracellular solute-binding protein family 1
EML4_RS20775	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
EML4_RS20785	ENOG4105FKQ	transcriptional regulator
EML4_RS20800	ENOG4105CBN	LysR family transcriptional regulator
EML4_RS20810	ENOG410836F	Transposase
EML4_RS20815	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
EML4_RS20820	ENOG4105C2J	ABC transporter
EML4_RS20825	ENOG4105CNN	ABC, transporter
EML4_RS20830	ENOG4105CNN	ABC, transporter
EML4_RS20835	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS20905	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
EML4_RS20915	ENOG4108VKQ	nitriC oxide reductase
EML4_RS20940	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
EML4_RS20945	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
EML4_RS20950	ENOG4105K78	MarR family Transcriptional regulator
EML4_RS20985	ENOG4108IY8	ABC, transporter
EML4_RS21010	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
EML4_RS21030	ENOG4108TSE	Transferase
EML4_RS21035	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
EML4_RS21040	ENOG4105WQI	isochorismatase
EML4_RS21045	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
EML4_RS21050	ENOG4105E4F	Isochorismate synthase
EML4_RS21060	ENOG4105C0W	non-ribosomal peptide synthetase
EML4_RS21065	ENOG4105CEY	Amp-dependent synthetase and ligase
EML4_RS21075	ENOG4105Q26	Siderophore-interacting protein
EML4_RS21085	ENOG4105EHG	Permease protein
EML4_RS21090	ENOG4105DQ5	transport system permease protein
EML4_RS21095	ENOG4105E0A	ABC, transporter
EML4_RS21110	ENOG4107RBR	Receptor
EML4_RS21115	ENOG4105C1G	acyl-Coa dehydrogenase
EML4_RS21120	ENOG4105ETT	transcriptional Regulator, LysR family
EML4_RS21125	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS21135	ENOG4105F38	ABC transporter, permease
EML4_RS21145	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS21155	ENOG4105CPN	adenine deaminase
EML4_RS21160	ENOG4107RSM	transcriptional regulator
EML4_RS21165	ENOG4105D94	Major Facilitator Superfamily
EML4_RS21170	ENOG4105CH2	amidohydrolase
EML4_RS21180	ENOG4108IGT	Dipeptidase
EML4_RS21185	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS21190	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS21195	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS21200	ENOG4105C3U	ABC transporter
EML4_RS21205	ENOG4108JQ7	(ABC) transporter
EML4_RS21210	ENOG4108M0I	Transcriptional regulator
EML4_RS21215	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS21225	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS21230	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EML4_RS21235	ENOG4107R7Y	intracellular protease Pfpi family
EML4_RS21245	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS21255	ENOG4107QSI	ABC, transporter
EML4_RS21260	ENOG4105CH2	amidohydrolase
EML4_RS21265	ENOG4108JQ6	ABC transporter
EML4_RS21270	ENOG4105DKT	Transcriptional regulator
EML4_RS21290	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS21295	ENOG4105CHR	reductase
EML4_RS21300	ENOG4105DEI	Mannitol dehydrogenase
EML4_RS21310	ENOG4105EF1	ribulokinase
EML4_RS21335	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EML4_RS21345	ENOG4105DKT	Transcriptional regulator
EML4_RS21350	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EML4_RS21355	ENOG4107258	Transcriptional regulator
EML4_RS21360	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
EML4_RS21370	ENOG4105CC5	ABC transporter
EML4_RS21375	ENOG4105CC5	ABC transporter
EML4_RS21380	ENOG4105DIK	(ABC) transporter
EML4_RS21385	ENOG4105DSE	periplasmic solute binding protein
EML4_RS21395	ENOG4108SKZ	Patatin-like phospholipase
EML4_RS21400	ENOG4105CRK	lysyL-tRNA synthetase
EML4_RS21405	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
EML4_RS21415	ENOG4105EE5	Membrane protein terC
EML4_RS21420	ENOG4105J7D	transcriptional regulator
EML4_RS21445	ENOG4105CMG	Carbohydrate kinase
EML4_RS21450	ENOG4105C93	Xylose Isomerase
EML4_RS21460	ENOG4108RCM	Nitroreductase
EML4_RS21465	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS21470	ENOG4108UMI	ABC transporter, permease
EML4_RS21475	ENOG4105D01	(LipO)protein
EML4_RS21480	ENOG4105BZU	Histidine kinase
EML4_RS21485	ENOG4105C72	UPF0176 protein
EML4_RS21500	ENOG4108UHU	Aldolase
EML4_RS21520	ENOG4105D7X	high-affinity nickel-transporter
EML4_RS21550	ENOG4105CKI	cobalamin synthesis protein
EML4_RS21560	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
EML4_RS21565	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS21570	ENOG4105C5I	Dehydrogenase
EML4_RS21580	ENOG4105DH8	myo-inositol catabolism
EML4_RS21590	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
EML4_RS21595	ENOG4105EDK	PfkB domain protein
EML4_RS21605	ENOG4108IV0	ABC, transporter
EML4_RS21610	ENOG4105C0Z	ABC transporter
EML4_RS21625	ENOG4105CAD	extracellular ligand-binding receptor
EML4_RS21640	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS21650	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
EML4_RS21655	ENOG4108JQ6	ABC transporter
EML4_RS21680	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
EML4_RS21685	ENOG4107S9B	Shikimate dehydrogenase
EML4_RS21690	ENOG4105CDA	abc transporter atp-binding protein
EML4_RS21695	ENOG4105CT1	(ABC) transporter
EML4_RS21700	ENOG4105CT1	(ABC) transporter
EML4_RS21705	ENOG4105E5Q	amino acid AbC transporter
EML4_RS21710	ENOG4105E5Q	amino acid AbC transporter
EML4_RS21715	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
EML4_RS21720	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
EML4_RS21725	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
EML4_RS21730	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
EML4_RS21740	ENOG4105DDW	LysR family Transcriptional regulator
EML4_RS21745	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
EML4_RS21755	ENOG4107HP6	Transcriptional regulator
EML4_RS21765	ENOG4107QNJ	CoA-transferase subunit B
EML4_RS21770	ENOG4105CHU	acetyl-coa acetyltransferase
EML4_RS21775	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS21795	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EML4_RS21805	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS21810	ENOG4105DRS	transport system, permease
EML4_RS21820	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS21830	ENOG4105F5H	Glycosyl Hydrolase Family 88
EML4_RS21850	ENOG4105EYM	Major Facilitator superfamily
EML4_RS21855	ENOG4105E0K	tonB-dependent siderophore receptor
EML4_RS21860	ENOG4108S3W	Anti-feci sigma factor, fecr
EML4_RS21870	ENOG4105E2R	ROK family
EML4_RS21875	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
EML4_RS21880	ENOG4108W6C	Dehydrogenase
EML4_RS21905	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS21910	ENOG4108I5D	sulfate abc transporter
EML4_RS21925	ENOG4108Z4U	Ferredoxin
EML4_RS21930	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EML4_RS21985	ENOG4105C09	Bile acid
EML4_RS21990	ENOG4105CPC	Aldo Keto reductase
EML4_RS21995	ENOG4105HEI	LysR family (Transcriptional regulator
EML4_RS22105	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
EML4_RS22110	ENOG4108KQJ	Type 11 methyltransferase
EML4_RS22150	ENOG4105C4R	Atp-dependent dna helicase
EML4_RS22160	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS22165	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EML4_RS22180	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
EML4_RS22195	ENOG4108JQ7	(ABC) transporter
EML4_RS22205	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS22210	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS22215	ENOG4107YCY	Transcriptional regulator
EML4_RS22235	ENOG4105BZU	Histidine kinase
EML4_RS22240	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
EML4_RS22250	ENOG4105FDF	Could be involved in DNA repair (By similarity)
EML4_RS22255	ENOG4105DQE	DNA ligase
EML4_RS22260	ENOG4105FDF	Could be involved in DNA repair (By similarity)
EML4_RS22265	ENOG4107QXV	Phosphate transporter
EML4_RS22270	ENOG4107GRR	phosphate transport regulator
EML4_RS22295	ENOG4106F60	Histidine kinase
EML4_RS22310	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
EML4_RS22325	ENOG4105E0K	tonB-dependent siderophore receptor
EML4_RS22335	ENOG4105DQ5	transport system permease protein
EML4_RS22340	ENOG4105TVJ	transport system, permease
EML4_RS22345	ENOG4105E0A	ABC, transporter
EML4_RS22350	ENOG4105DND	Transcriptional regulator
EML4_RS22360	ENOG4105CBG	Sulfatase
EML4_RS22365	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
EML4_RS22375	ENOG4106IQC	argininosuccinate lyase
EML4_RS22380	ENOG4105DRS	transport system, permease
EML4_RS22390	ENOG4107FKK	extracellular solute-binding protein family 1
EML4_RS22395	ENOG4107TFG	D-allose kinase
EML4_RS22435	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS22440	ENOG4108JQ5	ABC transporter
EML4_RS22445	ENOG4105F8D	glycoside hydrolase family 4
EML4_RS22450	ENOG4105D0S	secretion protein (HlyD
EML4_RS22455	ENOG4105CJ1	ABC, transporter
EML4_RS22460	ENOG4105CMI	transporter
EML4_RS22475	ENOG41074H6	response regulator
EML4_RS22480	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EML4_RS22490	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EML4_RS22495	ENOG4105DG4	malate L-lactate dehydrogenase
EML4_RS22510	ENOG4105E5Q	amino acid AbC transporter
EML4_RS22515	ENOG4105E5Q	amino acid AbC transporter
EML4_RS22535	ENOG4105CTU	Proline racemase
EML4_RS22540	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS22550	ENOG4105E89	ABC transporter
EML4_RS22555	ENOG4105E5Q	amino acid AbC transporter
EML4_RS22560	ENOG4105EAD	ABC transporter
EML4_RS22570	ENOG4105C5I	Dehydrogenase
EML4_RS22575	ENOG4105BZU	Histidine kinase
EML4_RS22590	ENOG4107QIZ	NADH dehydrogenase
EML4_RS22595	ENOG4108JB9	formate dehydrogenase
EML4_RS22610	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
EML4_RS22620	ENOG41073TP	transcriptional regulator
EML4_RS22630	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS22635	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS22640	ENOG4108JQ6	ABC transporter
EML4_RS22645	ENOG4105CXK	mandelate racemase muconate lactonizing
EML4_RS22655	ENOG4108QBF	Transcriptional regulator
EML4_RS22660	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS22670	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS22675	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EML4_RS22680	ENOG4108JQ6	ABC transporter
EML4_RS22685	ENOG4105ECY	inositol monophosphatase
EML4_RS22695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS22720	ENOG4105VDW	Csbd family
EML4_RS22730	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EML4_RS22740	ENOG4105BZ1	(ABC) transporter
EML4_RS22770	ENOG4107QIJ	Aconitate hydratase 2
EML4_RS22775	ENOG4105EQK	-acetyltransferase
EML4_RS22790	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
EML4_RS22810	ENOG4105C2J	ABC transporter
EML4_RS22815	ENOG4105CNN	ABC, transporter
EML4_RS22820	ENOG4105F5R	ABC transporter
EML4_RS22830	ENOG4105DBI	uridine monophosphokinase
EML4_RS22835	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
EML4_RS22865	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
EML4_RS22870	ENOG4105ENR	peptidase, M24
EML4_RS22895	ENOG4105C26	Dehydrogenase
EML4_RS22940	ENOG4105F4E	fad dependent oxidoreductase
EML4_RS22945	ENOG4105DTQ	mandelate racemase muconate lactonizing
EML4_RS22950	ENOG4105CDA	abc transporter atp-binding protein
EML4_RS22955	ENOG4105E5Q	amino acid AbC transporter
EML4_RS22965	ENOG4105ETT	transcriptional Regulator, LysR family
EML4_RS22970	ENOG4105CPT	Alpha beta hydrolase
EML4_RS22990	ENOG4105CQ0	ABC transporter
EML4_RS23000	ENOG4105Q95	Cupin 2, conserved barrel domain protein
EML4_RS23025	ENOG4105NPE	arsR family transcriptional regulator
EML4_RS23115	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EML4_RS23120	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EML4_RS23145	ENOG4105E1F	short-chain dehydrogenase reductase
EML4_RS23155	ENOG4105EQR	Transposase IS116 IS110 IS902
EML4_RS23170	ENOG4105EQX	glucarate dehydratase
EML4_RS23180	ENOG4105C5I	Dehydrogenase
EML4_RS23190	ENOG4105CHR	reductase
EML4_RS23200	ENOG4105E0S	extracellular solute-binding protein family 1
EML4_RS23205	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
EML4_RS23215	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS23220	ENOG4107XBN	GntR Family Transcriptional Regulator
EML4_RS23235	ENOG4105H1G	trap transporter solute receptor taxi family
EML4_RS23250	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
EML4_RS23265	ENOG4107S1E	Beta-lactamase
EML4_RS23275	ENOG4106TD9	Diguanylate cyclase
EML4_RS23320	ENOG4105D8X	mechanosensitive ion channel
EML4_RS23355	ENOG4107RTG	Major Facilitator superfamily
EML4_RS23390	ENOG4105K5G	30S ribosomal protein S21
EML4_RS23465	ENOG4105D74	hydrolase
EML4_RS23535	ENOG4108C33	Resolvase
EML4_RS23580	ENOG4105CDA	abc transporter atp-binding protein
EML4_RS23585	ENOG4106TNF	Periplasmic binding protein
EML4_RS23590	ENOG4105ETE	Transcriptional regulator (LacI family
EML4_RS23640	ENOG4105ENA	helicase
EML4_RS23770	ENOG4107XZA	Glycosyl transferase family 2
EML4_RS23805	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
EML4_RS23830	ENOG4105CPI	Metal Dependent Phosphohydrolase
EML4_RS23845	ENOG4105CMG	Carbohydrate kinase
EML4_RS23865	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EML4_RS23875	ENOG4107RHR	regulatoR
EML4_RS23960	ENOG4105EXG	Transcriptional regulator
EML4_RS23965	ENOG4105CHR	reductase
EML4_RS23970	ENOG4105KVH	Transcriptional regulator
EML4_RS23975	ENOG4105CHR	reductase
EML4_RS23985	ENOG4105KVH	Transcriptional regulator
EML4_RS23990	ENOG4105KVH	Transcriptional regulator
EML4_RS24020	ENOG4105DQE	DNA ligase
EML4_RS24035	ENOG4105E5W	Transporter
EML4_RS24040	ENOG4105DJ2	Major Facilitator Superfamily
EML4_RS24045	ENOG4108ZT1	Transcriptional regulator
EML4_RS24060	ENOG4105C2C	drug resistance transporter, Bcr CflA
EML4_RS24075	ENOG4105F7P	transcriptional regulator AsnC family
EML4_RS24150	ENOG4105E2R	ROK family
EML4_RS24155	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
EML4_RS24160	ENOG4105CNN	ABC, transporter
EML4_RS24165	ENOG4105C2J	ABC transporter
EML4_RS24170	ENOG4105EF1	ribulokinase
EML4_RS24175	ENOG4105E98	transcriptional regulator DeoR family
EML4_RS24180	ENOG4105CHR	reductase
EML4_RS24215	ENOG4108R85	Short chain dehydrogenase
EML4_RS24230	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EML4_RS24270	ENOG410642W	LysR family Transcriptional regulator
EML4_RS24280	ENOG4105CHR	reductase
EML4_RS24285	ENOG4105K56	Transcriptional regulator
EML4_RS24295	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
EML4_RS24300	ENOG4105VGJ	Virulence-associated protein
EML4_RS24305	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
EML4_RS24315	ENOG410829K	Lysine exporter protein (Lyse ygga)
EML4_RS24325	ENOG4108XFH	Transcriptional regulator
EML4_RS24335	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EML4_RS24340	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
EML4_RS24350	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
EML4_RS24355	ENOG4105CPC	Aldo Keto reductase
EML4_RS24365	ENOG4105D3W	isochorismatase
EML4_RS24375	ENOG4105CHR	reductase
EML4_RS24380	ENOG4105CF7	AraC family transcriptional regulator
EML4_RS24395	ENOG4105CBN	LysR family transcriptional regulator
EML4_RS24405	ENOG4108IXY	short-chain dehydrogenase reductase
EML4_RS24420	ENOG4105BZW	Glycerate kinase
EML4_RS24475	ENOG4107QM5	aconitate hydratase
EML4_RS24480	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
EML4_RS24500	ENOG4105EMN	RNA polymerase sigma factor
EML4_RS24505	ENOG4105EQ2	LysR family Transcriptional regulator
EML4_RS24520	ENOG4105E7U	AraC family transcriptional regulator
EML4_RS24530	ENOG4105EMU	Dehydrogenase
EML4_RS24550	ENOG4105EMU	Dehydrogenase
EML4_RS24555	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
EML4_RS24565	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
EML4_RS24575	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
EML4_RS24590	ENOG4105EUB	pirin domain protein
EML4_RS24595	ENOG4105EQ1	Transcriptional regulator
EML4_RS24615	ENOG4105WH1	Two component transcriptional regulator luxr family
EML4_RS24620	ENOG4105ENE	Histidine kinase
EML4_RS24635	ENOG4105CS1	NAD(P)H quinone oxidoreductase
EML4_RS24645	ENOG4105VSH	4-oxalocrotonate tautomerase
EML4_RS24660	ENOG4108A65	Transcriptional regulator
EML4_RS24675	ENOG4105D6J	arsenicaL-resistance protein
EML4_RS24720	ENOG4108Z9Z	response to DNA damage stimulus
EML4_RS24775	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
EML4_RS24830	ENOG4105HEI	LysR family (Transcriptional regulator
EML4_RS24850	ENOG4108IMY	Transcriptional regulator
EML4_RS24855	ENOG4108Z7F	N-acetyltransferase
EML4_RS24865	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EML4_RS24885	ENOG4105CH5	extracellular solute-binding protein, family 7
EML4_RS24890	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EML4_RS24905	ENOG4108ZNX	Heat shock protein
EML4_RS24920	ENOG4107R3N	Filamentation induced by cAMP protein fic
EML4_RS24930	ENOG4105F9F	transposase
EML4_RS24935	ENOG4107YBY	Hydrolase
EML4_RS24965	ENOG4105D7N	magnesium and cobalt transport protein CorA
EML4_RS24970	ENOG4105CKW	Inner membrane protein yedI
EML4_RS24995	ENOG410903D	sensor protein
EML4_RS25005	ENOG4105C7B	Threonine dehydratase
EML4_RS25010	ENOG4105CHR	reductase
EML4_RS25015	ENOG4108FUF	Transcriptional regulator, IclR family
EML4_RS25020	ENOG4105CMR	udp-glucose 4-epimerase
EML4_RS25025	ENOG4108IJ9	(ABC) transporter
EML4_RS25030	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
EML4_RS25035	ENOG4105D56	permease protein
EML4_RS25045	ENOG4105CXK	mandelate racemase muconate lactonizing
EML4_RS25050	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EML4_RS25055	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
EML4_RS25085	ENOG4107QN2	dihydrolipoyl dehydrogenase
EML4_RS25100	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
EML4_RS25105	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EML4_RS25145	ENOG4105K2J	Transcriptional regulator
EML4_RS25150	ENOG4105DIA	mandelate racemase muconate lactonizing
EML4_RS25155	ENOG4107RSM	transcriptional regulator
EML4_RS25195	ENOG4105E80	TraG TraD family protein
EML4_RS25205	ENOG4105K70	DNA-binding protein
EML4_RS25215	ENOG4108EHY	type IV secretion system
EML4_RS25220	ENOG4105CMA	conjugation trbi family protein
EML4_RS25230	ENOG4108V42	Type IV secretion system protein VirB8
EML4_RS25295	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EML4_RS25345	ENOG4108JGH	Tetr family transcriptional regulator
EML4_RS25360	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
EML4_RS25365	ENOG4105DHQ	Histidine kinase
EML4_RS25370	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EML4_RS25375	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
EML4_RS25380	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EML4_RS25385	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
EML4_RS25415	ENOG4105JSC	dimethylmenaquinone methyltransferase
EML4_RS25430	ENOG4108JQ6	ABC transporter
EML4_RS25435	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS25445	ENOG4106R87	Extracellular solute-binding protein, family 5
EML4_RS25450	ENOG4108RYR	transcriptional regulator AsnC family
EML4_RS25455	ENOG4105C26	Dehydrogenase
EML4_RS25460	ENOG4105C8Y	Acetylornithine aminotransferase
EML4_RS25480	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
EML4_RS25510	ENOG4105S66	prophage protein
EML4_RS25525	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
EML4_RS25545	ENOG4105CT1	(ABC) transporter
EML4_RS25550	ENOG4105E5Q	amino acid AbC transporter
EML4_RS25560	ENOG4105CDA	abc transporter atp-binding protein
EML4_RS25570	ENOG4105JXH	GntR family transcriptional regulator
EML4_RS25585	ENOG4105CXK	mandelate racemase muconate lactonizing
EML4_RS25595	ENOG4105DRR	Transcriptional regulator, GntR family
EML4_RS25605	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS25610	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS25625	ENOG4107S5I	aldo keto reductase
EML4_RS25630	ENOG4105EQ2	LysR family Transcriptional regulator
EML4_RS25670	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EML4_RS25690	ENOG4106PMH	Extracellular solute-binding protein family 3
EML4_RS25755	ENOG4105K56	Transcriptional regulator
EML4_RS25765	ENOG4105EQR	Transposase IS116 IS110 IS902
EML4_RS25770	ENOG4105EQR	Transposase IS116 IS110 IS902
EML4_RS25810	ENOG4105BZU	Histidine kinase
EML4_RS25860	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EML4_RS25865	ENOG4108R85	Short chain dehydrogenase
EML4_RS25875	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
EML4_RS25880	ENOG4105CNN	ABC, transporter
EML4_RS25885	ENOG4108HHA	Transketolase
EML4_RS25890	ENOG4108IUS	Transketolase
EML4_RS25895	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EML4_RS25900	ENOG4107RHR	regulatoR
EML4_RS25910	ENOG4105ECQ	AraC Family Transcriptional Regulator
EML4_RS25920	ENOG4108Z0R	Transferase
EML4_RS25960	ENOG4105BZU	Histidine kinase
EML4_RS25995	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EML4_RS26000	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
EML4_RS26010	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS26015	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EML4_RS26030	ENOG4107KJX	Transcriptional regulator
EML4_RS26035	ENOG4105ECK	Fatty Acid Desaturase
EML4_RS26040	ENOG4105BZU	Histidine kinase
EML4_RS26070	ENOG4105BZU	Histidine kinase
EML4_RS26090	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
EML4_RS26095	ENOG4105BZU	Histidine kinase
EML4_RS26100	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EML4_RS26155	ENOG4105EJC	lysr family transcriptional regulator
EML4_RS26175	ENOG4105HEI	LysR family (Transcriptional regulator
EML4_RS26250	ENOG4105ETT	transcriptional Regulator, LysR family
EML4_RS26260	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
EML4_RS26265	ENOG4105D7T	ABC transporter
EML4_RS26270	ENOG4107Z6I	Thiamine biosynthesis protein
EML4_RS26285	ENOG4105CHR	reductase
EML4_RS26315	ENOG4105CNN	ABC, transporter
EML4_RS26320	ENOG4105C2J	ABC transporter
EML4_RS26345	ENOG4108JQ6	ABC transporter
EML4_RS26350	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS26365	ENOG4105CPU	Monooxygenase
EML4_RS26375	ENOG4105CBN	LysR family transcriptional regulator
EML4_RS26400	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
EML4_RS26405	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
EML4_RS26425	ENOG4105DQE	DNA ligase
EML4_RS26485	ENOG4105FA0	parb-like partition protein
EML4_RS26505	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
EML4_RS26550	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EML4_RS26570	ENOG4105K70	DNA-binding protein
EML4_RS26630	ENOG4107SDU	Methyl-accepting chemotaxis
EML4_RS26650	ENOG4105EAM	Na Pi-cotransporter
EML4_RS26665	ENOG4105DEF	Extracellular solute-binding protein, family 5
EML4_RS26670	ENOG4105C3U	ABC transporter
EML4_RS26685	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EML4_RS26690	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
EML4_RS26695	ENOG4105ECY	inositol monophosphatase
EML4_RS27030	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
EML4_RS27040	ENOG4107RSM	transcriptional regulator