locus-tag	class	description
FY138_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY138_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY138_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY138_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY138_RS00025	COG1420	regulation of RNA biosynthetic process
FY138_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY138_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY138_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY138_RS00050	COG1137	ATPase activity
FY138_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY138_RS00065	COG0616	signal peptide processing
FY138_RS00070	COG0776	regulation of translation
FY138_RS00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY138_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY138_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY138_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY138_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY138_RS00115	COG0728	peptidoglycan biosynthetic process
FY138_RS00125	COG0180	Tryptophanyl-tRNA synthetase
FY138_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY138_RS00140	COG1214	PFAM Peptidase M22, glycoprotease
FY138_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY138_RS00165	COG1702	phosphate starvation-inducible protein PhoH
FY138_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY138_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY138_RS00185	COG1396	sequence-specific DNA binding
FY138_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY138_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY138_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_RS00210	COG0242	peptide deformylase activity
FY138_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY138_RS00220	COG0101	tRNA pseudouridine synthase activity
FY138_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY138_RS00235	COG2171	N-acyltransferase activity
FY138_RS00245	COG0840	transmembrane signaling receptor activity
FY138_RS00250	COG1957	nucleoside hydrolase
FY138_RS00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY138_RS00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY138_RS00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY138_RS00295	COG0706	membrane insertase activity
FY138_RS00300	COG0594	ribonuclease P activity
FY138_RS00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY138_RS00310	COG0840	transmembrane signaling receptor activity
FY138_RS00325	COG2226	methyltransferase
FY138_RS00330	COG3842	ATPase activity
FY138_RS00335	COG1175	transmembrane transport
FY138_RS00340	COG0395	ABC-type sugar transport system, permease component
FY138_RS00355	COG0427	acetyl-CoA hydrolase
FY138_RS00365	COG3938	Belongs to the proline racemase family
FY138_RS00370	COG0418	dihydroorotase activity
FY138_RS00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY138_RS00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY138_RS00400	COG0166	Belongs to the GPI family
FY138_RS00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY138_RS00410	COG3842	ATPase activity
FY138_RS00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY138_RS00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY138_RS00425	COG4774	siderophore transport
FY138_RS00470	COG2326	polyphosphate kinase activity
FY138_RS00475	COG5002	protein histidine kinase activity
FY138_RS00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY138_RS00485	COG0573	inorganic phosphate transmembrane transporter activity
FY138_RS00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY138_RS00500	COG0704	Plays a role in the regulation of phosphate uptake
FY138_RS00505	COG0745	RESPONSE REGULATOR receiver
FY138_RS00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY138_RS00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY138_RS00530	COG2967	ApaG domain
FY138_RS00540	COG0717	Belongs to the dCTP deaminase family
FY138_RS00600	COG3561	AntA/AntB antirepressor
FY138_RS00680	COG5484	DNA packaging
FY138_RS00680	COG3728	DNA packaging
FY138_RS00805	COG0582	viral genome integration into host DNA
FY138_RS00830	COG0419	ATPase involved in DNA repair
FY138_RS00850	COG1396	sequence-specific DNA binding
FY138_RS00890	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY138_RS00895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY138_RS00945	COG0167	dihydroorotate dehydrogenase activity
FY138_RS00980	COG1959	2 iron, 2 sulfur cluster binding
FY138_RS00985	COG1201	RNA secondary structure unwinding
FY138_RS01015	COG1960	acyl-CoA dehydrogenase activity
FY138_RS01020	COG0183	Belongs to the thiolase family
FY138_RS01025	COG1024	Enoyl-CoA hydratase
FY138_RS01025	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY138_RS01050	COG1320	monovalent cation:proton antiporter activity
FY138_RS01055	COG2212	antiporter activity
FY138_RS01060	COG1863	multisubunit Na H antiporter MnhE subunit
FY138_RS01065	COG0651	ATP synthesis coupled electron transport
FY138_RS01070	COG1006	Multisubunit Na H antiporter MnhC subunit
FY138_RS01075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY138_RS01075	COG2111	Na H antiporter
FY138_RS01085	COG0840	transmembrane signaling receptor activity
FY138_RS01095	COG0745	RESPONSE REGULATOR receiver
FY138_RS01100	COG0643	Histidine kinase
FY138_RS01100	COG2198	Histidine kinase
FY138_RS01105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY138_RS01110	COG2201	protein-glutamate methylesterase activity
FY138_RS01115	COG0745	RESPONSE REGULATOR receiver
FY138_RS01120	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY138_RS01130	COG1766	The M ring may be actively involved in energy transduction
FY138_RS01135	COG2771	luxR family
FY138_RS01145	COG0840	transmembrane signaling receptor activity
FY138_RS01145	COG2972	Histidine kinase
FY138_RS01150	COG0784	Response regulator, receiver
FY138_RS01150	COG2205	protein histidine kinase activity
FY138_RS01150	COG2198	Histidine kinase
FY138_RS01155	COG1970	mechanosensitive ion channel activity
FY138_RS01160	COG0436	Aminotransferase
FY138_RS01175	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY138_RS01180	COG0424	maF-like protein
FY138_RS01185	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY138_RS01195	COG5328	Belongs to the UPF0262 family
FY138_RS01200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY138_RS01210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY138_RS01230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY138_RS01240	COG1338	Plays a role in the flagellum-specific transport system
FY138_RS01250	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY138_RS01260	COG1706	bacterial-type flagellum-dependent cell motility
FY138_RS01265	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY138_RS01270	COG4786	Flagellar basal body rod
FY138_RS01275	COG1677	Flagellar hook-basal body complex protein FliE
FY138_RS01280	COG1558	bacterial-type flagellum-dependent cell motility
FY138_RS01285	COG1815	bacterial-type flagellum-dependent cell motility
FY138_RS01295	COG1157	protein secretion by the type III secretion system
FY138_RS01300	COG4786	Flagellar basal body rod
FY138_RS01310	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY138_RS01315	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY138_RS01320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY138_RS01325	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY138_RS01330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY138_RS01350	COG1360	Flagellar Motor Protein
FY138_RS01395	COG5443	negative regulation of bacterial-type flagellum assembly
FY138_RS01400	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY138_RS01410	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY138_RS01450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY138_RS01455	COG1609	Transcriptional regulator
FY138_RS01460	COG1653	transport
FY138_RS01465	COG1175	transmembrane transport
FY138_RS01470	COG0395	ABC-type sugar transport system, permease component
FY138_RS01475	COG0366	Alpha amylase catalytic
FY138_RS01480	COG3842	ATPase activity
FY138_RS01495	COG0129	dihydroxy-acid dehydratase activity
FY138_RS01500	COG0363	glucosamine-6-phosphate deaminase activity
FY138_RS01505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY138_RS01510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS01520	COG2081	HI0933 family
FY138_RS01540	COG2224	Isocitrate lyase
FY138_RS01555	COG3842	ATPase activity
FY138_RS01560	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_RS01565	COG1177	transmembrane transport
FY138_RS01580	COG2205	protein histidine kinase activity
FY138_RS01590	COG0248	Ppx GppA phosphatase
FY138_RS01595	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY138_RS01600	COG0477	Major facilitator Superfamily
FY138_RS01630	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY138_RS01635	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY138_RS01645	COG0142	geranyltranstransferase activity
FY138_RS01670	COG0752	glycyl-tRNA synthetase alpha subunit
FY138_RS01680	COG1704	LemA family
FY138_RS01685	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY138_RS01695	COG0751	glycine-tRNA ligase activity
FY138_RS01700	COG1683	Conserved Protein
FY138_RS01705	COG0840	transmembrane signaling receptor activity
FY138_RS01715	COG0151	Belongs to the GarS family
FY138_RS01720	COG2183	response to ionizing radiation
FY138_RS01725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY138_RS01750	COG0583	DNA-binding transcription factor activity
FY138_RS01770	COG0306	phosphate transporter
FY138_RS01780	COG0561	phosphatase activity
FY138_RS01785	COG0438	transferase activity, transferring glycosyl groups
FY138_RS01790	COG2186	Transcriptional regulator
FY138_RS01805	COG0583	DNA-binding transcription factor activity
FY138_RS01810	COG0277	FAD linked oxidase domain protein
FY138_RS01815	COG0277	FAD linked oxidase domain protein
FY138_RS01820	COG0247	lactate metabolic process
FY138_RS01830	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_RS01835	COG2818	Glycosylase
FY138_RS01845	COG2855	membrane
FY138_RS01850	COG0583	DNA-binding transcription factor activity
FY138_RS01880	COG0124	histidyl-tRNA synthetase
FY138_RS01890	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY138_RS01895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY138_RS01900	COG2259	Doxx family
FY138_RS01910	COG0459	protein refolding
FY138_RS01915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY138_RS01925	COG0196	riboflavin kinase activity
FY138_RS01930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY138_RS01940	COG0590	tRNA wobble adenosine to inosine editing
FY138_RS01945	COG1187	pseudouridine synthase activity
FY138_RS01950	COG0742	ribosomal rna small subunit methyltransferase
FY138_RS01955	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY138_RS01965	COG0312	modulator of DNA gyrase
FY138_RS01970	COG0483	inositol monophosphate 1-phosphatase activity
FY138_RS01980	COG1519	Transferase
FY138_RS01990	COG1663	tetraacyldisaccharide 4'-kinase activity
FY138_RS02000	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY138_RS02005	COG0745	RESPONSE REGULATOR receiver
FY138_RS02010	COG5001	Diguanylate cyclase
FY138_RS02010	COG3300	MHYT domain
FY138_RS02015	COG3386	PFAM SMP-30 Gluconolaconase
FY138_RS02020	COG0800	Aldolase
FY138_RS02025	COG3734	2-keto-3-deoxy-galactonokinase
FY138_RS02030	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS02035	COG1414	Transcriptional regulator
FY138_RS02040	COG2197	response regulator
FY138_RS02055	COG0598	Magnesium transport protein CorA
FY138_RS02060	COG3158	transport of potassium into the cell
FY138_RS02075	COG0356	it plays a direct role in the translocation of protons across the membrane
FY138_RS02085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY138_RS02090	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY138_RS02105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY138_RS02125	COG0009	L-threonylcarbamoyladenylate synthase
FY138_RS02135	COG4638	Rieske (2fe-2S)
FY138_RS02160	COG1960	acyl-CoA dehydrogenase activity
FY138_RS02175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY138_RS02180	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY138_RS02185	COG0840	transmembrane signaling receptor activity
FY138_RS02195	COG1522	sequence-specific DNA binding
FY138_RS02220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY138_RS02225	COG1741	Belongs to the pirin family
FY138_RS02230	COG1722	exodeoxyribonuclease VII activity
FY138_RS02235	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY138_RS02240	COG1268	BioY protein
FY138_RS02245	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY138_RS02250	COG1122	ATPase activity
FY138_RS02255	COG3214	Protein conserved in bacteria
FY138_RS02260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY138_RS02260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY138_RS02265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY138_RS02285	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY138_RS02300	COG0259	pyridoxamine-phosphate oxidase activity
FY138_RS02330	COG0312	modulator of DNA gyrase
FY138_RS02345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY138_RS02350	COG0109	protoheme IX farnesyltransferase activity
FY138_RS02360	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY138_RS02375	COG3346	SURF1 family
FY138_RS02380	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY138_RS02385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY138_RS02390	COG0328	RNA-DNA hybrid ribonuclease activity
FY138_RS02400	COG0678	peroxiredoxin activity
FY138_RS02400	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY138_RS02410	COG1678	Uncharacterized ACR, COG1678
FY138_RS02415	COG3237	CsbD-like
FY138_RS02425	COG5001	Diguanylate cyclase
FY138_RS02425	COG3300	MHYT domain
FY138_RS02430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY138_RS02435	COG0612	Peptidase, M16
FY138_RS02460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY138_RS02465	COG1802	Transcriptional regulator
FY138_RS02480	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY138_RS02485	COG3609	addiction module antidote protein, CC2985 family
FY138_RS02490	COG3668	Plasmid stabilization system
FY138_RS02500	COG1194	a g-specific adenine glycosylase
FY138_RS02515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY138_RS02520	COG1196	nuclear chromosome segregation
FY138_RS02525	COG2514	catechol 2,3-dioxygenase activity
FY138_RS02530	COG0574	Belongs to the PEP-utilizing enzyme family
FY138_RS02530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY138_RS02540	COG1823	symporter activity
FY138_RS02565	COG0579	oxidoreductase
FY138_RS02580	COG2895	sulfate adenylyltransferase (ATP) activity
FY138_RS02585	COG0175	sulfate reduction
FY138_RS02590	COG0175	sulfate reduction
FY138_RS02595	COG1959	2 iron, 2 sulfur cluster binding
FY138_RS02600	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY138_RS02605	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY138_RS02610	COG4208	sulfate ABC transporter
FY138_RS02615	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY138_RS02625	COG2203	Gaf domain
FY138_RS02625	COG2199	diguanylate cyclase activity
FY138_RS02625	COG2200	EAL domain
FY138_RS02635	COG1309	transcriptional regulator
FY138_RS02640	COG1012	belongs to the aldehyde dehydrogenase family
FY138_RS02645	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY138_RS02675	COG0625	glutathione transferase activity
FY138_RS02685	COG0477	Major facilitator Superfamily
FY138_RS02695	COG3657	addiction module killer protein
FY138_RS02705	COG1793	dna ligase
FY138_RS02725	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_RS02730	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_RS02735	COG1846	Transcriptional regulator
FY138_RS02740	COG1764	response to oxidative stress
FY138_RS02755	COG0488	(ABC) transporter
FY138_RS02790	COG4221	oxidoreductase activity
FY138_RS02805	COG0433	COG0433 Predicted ATPase
FY138_RS02815	COG1733	regulation of RNA biosynthetic process
FY138_RS02820	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY138_RS02835	COG0656	L-ascorbic acid biosynthetic process
FY138_RS02840	COG3781	membrane
FY138_RS02845	COG2378	regulation of single-species biofilm formation
FY138_RS02855	COG4106	trans-aconitate 2-methyltransferase activity
FY138_RS02860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY138_RS02865	COG0840	transmembrane signaling receptor activity
FY138_RS02870	COG0583	DNA-binding transcription factor activity
FY138_RS02885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY138_RS02905	COG3909	cytochrome
FY138_RS02910	COG2010	Cytochrome c
FY138_RS02945	COG0789	Transcriptional regulator
FY138_RS02970	COG4175	Glycine betaine
FY138_RS02970	COG0517	IMP dehydrogenase activity
FY138_RS02975	COG4176	ABC-type proline glycine betaine transport system permease component
FY138_RS02995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_RS03005	COG2169	Transcriptional regulator
FY138_RS03005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY138_RS03015	COG2514	catechol 2,3-dioxygenase activity
FY138_RS03030	COG1272	protein, Hemolysin III
FY138_RS03040	COG1280	lysine exporter protein (LysE YggA)
FY138_RS03045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY138_RS03050	COG2111	Na H antiporter
FY138_RS03050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY138_RS03055	COG2111	Na H antiporter
FY138_RS03060	COG1006	Multisubunit Na H antiporter MnhC subunit
FY138_RS03065	COG0651	ATP synthesis coupled electron transport
FY138_RS03070	COG1863	multisubunit Na H antiporter MnhE subunit
FY138_RS03075	COG2212	antiporter activity
FY138_RS03080	COG1320	monovalent cation:proton antiporter activity
FY138_RS03085	COG4957	zinc ion binding
FY138_RS03100	COG2166	iron-sulfur cluster assembly
FY138_RS03110	COG2205	protein histidine kinase activity
FY138_RS03155	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY138_RS03160	COG2983	Belongs to the UPF0260 family
FY138_RS03175	COG2217	Heavy metal translocating P-type atpase
FY138_RS03205	COG2814	Major facilitator Superfamily
FY138_RS03215	COG1621	beta-fructofuranosidase activity
FY138_RS03220	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY138_RS03270	COG4695	Portal protein
FY138_RS03375	COG4235	cytochrome complex assembly
FY138_RS03380	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY138_RS03385	COG1138	Cytochrome C-type biogenesis protein
FY138_RS03390	COG3088	subunit of a heme lyase
FY138_RS03395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY138_RS03400	COG0745	RESPONSE REGULATOR receiver
FY138_RS03405	COG2205	protein histidine kinase activity
FY138_RS03410	COG3011	Protein conserved in bacteria
FY138_RS03415	COG3713	MltA-interacting MipA family protein
FY138_RS03420	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY138_RS03425	COG2202	Pas domain
FY138_RS03425	COG2205	protein histidine kinase activity
FY138_RS03435	COG0308	aminopeptidase N
FY138_RS03440	COG0697	spore germination
FY138_RS03455	COG0443	Heat shock 70 kDa protein
FY138_RS03490	COG0604	alcohol dehydrogenase
FY138_RS03495	COG1733	regulation of RNA biosynthetic process
FY138_RS03500	COG1968	undecaprenyl-diphosphatase activity
FY138_RS03505	COG2239	Acts as a magnesium transporter
FY138_RS03510	COG2814	Major facilitator Superfamily
FY138_RS03535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY138_RS03565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY138_RS03610	COG0741	lytic transglycosylase activity
FY138_RS03615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_RS03620	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY138_RS03625	COG0840	transmembrane signaling receptor activity
FY138_RS03635	COG1758	RNA polymerase activity
FY138_RS03655	COG0736	holo-[acyl-carrier-protein] synthase activity
FY138_RS03660	COG0681	Belongs to the peptidase S26 family
FY138_RS03665	COG0571	ribonuclease III activity
FY138_RS03670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY138_RS03680	COG0784	Response regulator, receiver
FY138_RS03685	COG1381	Involved in DNA repair and RecF pathway recombination
FY138_RS03695	COG2226	methyltransferase
FY138_RS03705	COG1418	mRNA catabolic process
FY138_RS03715	COG0346	lactoylglutathione lyase activity
FY138_RS03730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_RS03735	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY138_RS03740	COG0668	transmembrane transport
FY138_RS03750	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY138_RS03780	COG1742	UPF0060 membrane protein
FY138_RS03800	COG1183	phosphatidylcholine synthase activity
FY138_RS03805	COG0688	phosphatidylethanolamine metabolic process
FY138_RS03810	COG5265	(ABC) transporter
FY138_RS03850	COG2852	Protein conserved in bacteria
FY138_RS03855	COG0215	cysteine-tRNA ligase activity
FY138_RS03860	COG4221	oxidoreductase activity
FY138_RS03865	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY138_RS03870	COG1286	toxin biosynthetic process
FY138_RS03885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY138_RS03895	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY138_RS03905	COG0305	Participates in initiation and elongation during chromosome replication
FY138_RS03925	COG0359	binds to the 23S rRNA
FY138_RS03935	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY138_RS03940	COG0360	Binds together with S18 to 16S ribosomal RNA
FY138_RS03950	COG0667	Aldo Keto reductase
FY138_RS03955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY138_RS03965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY138_RS03970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY138_RS03980	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY138_RS03985	COG1561	YicC-like family, N-terminal region
FY138_RS03990	COG0194	GDP metabolic process
FY138_RS04005	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY138_RS04010	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY138_RS04020	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY138_RS04035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY138_RS04055	COG5001	Diguanylate cyclase
FY138_RS04055	COG2203	Gaf domain
FY138_RS04055	COG4251	negative regulation of phosphorylation
FY138_RS04055	COG3706	GGDEF domain
FY138_RS04060	COG3300	MHYT domain
FY138_RS04060	COG5001	Diguanylate cyclase
FY138_RS04065	COG4191	Histidine kinase
FY138_RS04070	COG4566	intracellular signal transduction
FY138_RS04080	COG0488	(ABC) transporter
FY138_RS04085	COG3706	GGDEF domain
FY138_RS04095	COG0105	UTP biosynthetic process
FY138_RS04115	COG0314	molybdopterin synthase activity
FY138_RS04125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY138_RS04130	COG0322	excinuclease ABC activity
FY138_RS04135	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS04160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY138_RS04165	COG0243	molybdopterin cofactor binding
FY138_RS04180	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY138_RS04185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY138_RS04190	COG2226	methyltransferase
FY138_RS04195	COG0628	permease
FY138_RS04205	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY138_RS04210	COG0248	Ppx GppA phosphatase
FY138_RS04235	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY138_RS04245	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY138_RS04250	COG0477	Major facilitator Superfamily
FY138_RS04255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY138_RS04265	COG0840	transmembrane signaling receptor activity
FY138_RS04270	COG0659	secondary active sulfate transmembrane transporter activity
FY138_RS04280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY138_RS04285	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY138_RS04295	COG0113	porphobilinogen synthase activity
FY138_RS04315	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY138_RS04320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY138_RS04325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY138_RS04325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY138_RS04335	COG1280	lysine exporter protein (LysE YggA)
FY138_RS04340	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY138_RS04345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY138_RS04350	COG2814	Major facilitator Superfamily
FY138_RS04355	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY138_RS04375	COG0416	fatty acid biosynthetic process
FY138_RS04380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY138_RS04385	COG0776	regulation of translation
FY138_RS04420	COG0601	transmembrane transport
FY138_RS04425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS04430	COG0444	Belongs to the ABC transporter superfamily
FY138_RS04440	COG0747	negative chemotaxis
FY138_RS04450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY138_RS04455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY138_RS04470	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY138_RS04475	COG0583	DNA-binding transcription factor activity
FY138_RS04480	COG0737	Belongs to the 5'-nucleotidase family
FY138_RS04500	COG2897	thiosulfate sulfurtransferase activity
FY138_RS04515	COG0415	Belongs to the DNA photolyase family
FY138_RS04525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY138_RS04555	COG3932	Exopolysaccharide synthesis, ExoD
FY138_RS04560	COG1238	metal cluster binding
FY138_RS04635	COG1612	heme a metabolic process
FY138_RS04645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY138_RS04650	COG0010	Belongs to the arginase family
FY138_RS04655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY138_RS04660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY138_RS04670	COG1832	CoA-binding protein
FY138_RS04695	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS04700	COG2124	cytochrome p450
FY138_RS04705	COG2199	diguanylate cyclase activity
FY138_RS04710	COG0740	serine-type endopeptidase activity
FY138_RS04715	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY138_RS04720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY138_RS04730	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY138_RS04760	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY138_RS04765	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY138_RS04770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY138_RS04780	COG0649	NAD binding
FY138_RS04790	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY138_RS04795	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY138_RS04805	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY138_RS04810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY138_RS04820	COG0713	ATP synthesis coupled electron transport
FY138_RS04835	COG1007	ATP synthesis coupled electron transport
FY138_RS04840	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY138_RS04840	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY138_RS04855	COG0442	prolyl-tRNA aminoacylation
FY138_RS04865	COG1136	(ABC) transporter
FY138_RS04880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY138_RS04900	COG0784	Response regulator, receiver
FY138_RS04910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY138_RS04915	COG0477	Major facilitator Superfamily
FY138_RS04930	COG0557	exoribonuclease II activity
FY138_RS04935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY138_RS04945	COG0758	DNA mediated transformation
FY138_RS04950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY138_RS04960	COG0540	Belongs to the ATCase OTCase family
FY138_RS04975	COG1960	acyl-CoA dehydrogenase activity
FY138_RS04980	COG0456	acetyltransferase
FY138_RS05000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY138_RS05005	COG2824	Alkylphosphonate utilization operon protein PhnA
FY138_RS05010	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY138_RS05015	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY138_RS05020	COG0154	amidase activity
FY138_RS05025	COG0456	acetyltransferase
FY138_RS05030	COG3811	Belongs to the UPF0386 family
FY138_RS05045	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY138_RS05075	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY138_RS05080	COG0439	Biotin carboxylase
FY138_RS05085	COG0511	ligase activity, forming carbon-carbon bonds
FY138_RS05090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY138_RS05100	COG0436	Aminotransferase
FY138_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS05125	COG1530	ribonuclease E activity
FY138_RS05135	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY138_RS05155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY138_RS05160	COG0384	phenazine biosynthesis protein PhzF
FY138_RS05180	COG0633	Ferredoxin
FY138_RS05190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FY138_RS05195	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY138_RS05200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY138_RS05210	COG3768	UPF0283 membrane protein
FY138_RS05215	COG3106	COG3106 Predicted ATPase
FY138_RS05245	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY138_RS05280	COG0537	adenosine 5'-monophosphoramidase activity
FY138_RS05310	COG0052	Belongs to the universal ribosomal protein uS2 family
FY138_RS05315	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY138_RS05320	COG0528	UMP kinase activity
FY138_RS05325	COG0233	cytoplasmic translational termination
FY138_RS05330	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY138_RS05340	COG0750	zinc metalloprotease
FY138_RS05345	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY138_RS05350	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY138_RS05355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY138_RS05360	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY138_RS05365	COG3494	Protein of unknown function (DUF1009)
FY138_RS05370	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY138_RS05375	COG2186	Transcriptional regulator
FY138_RS05385	COG0765	amino acid transport
FY138_RS05390	COG0765	amino acid transport
FY138_RS05400	COG0372	Belongs to the citrate synthase family
FY138_RS05415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY138_RS05440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY138_RS05445	COG1459	type II secretion system
FY138_RS05500	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY138_RS05505	COG0148	phosphopyruvate hydratase activity
FY138_RS05515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY138_RS05520	COG0022	dehydrogenase e1 component
FY138_RS05520	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY138_RS05525	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY138_RS05535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY138_RS05545	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY138_RS05550	COG0697	spore germination
FY138_RS05570	COG2867	negative regulation of translational initiation
FY138_RS05575	COG1546	Belongs to the CinA family
FY138_RS05580	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY138_RS05580	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY138_RS05590	COG3852	Histidine kinase
FY138_RS05595	COG2204	response regulator
FY138_RS05600	COG5000	phosphorelay sensor kinase activity
FY138_RS05605	COG2204	response regulator
FY138_RS05610	COG0569	domain protein
FY138_RS05615	COG1923	regulation of RNA biosynthetic process
FY138_RS05620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY138_RS05625	COG3956	TIGRFAM MazG family protein
FY138_RS05635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY138_RS05635	COG1648	precorrin-2 dehydrogenase activity
FY138_RS05675	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY138_RS05675	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY138_RS05680	COG0509	glycine decarboxylation via glycine cleavage system
FY138_RS05685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY138_RS05710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY138_RS05715	COG0564	pseudouridine synthase activity
FY138_RS05735	COG0251	oxidation-reduction process
FY138_RS05740	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY138_RS05750	COG1671	Belongs to the UPF0178 family
FY138_RS05765	COG0450	alkyl hydroperoxide reductase
FY138_RS05770	COG0625	glutathione transferase activity
FY138_RS05790	COG0431	NADPH-dependent FMN reductase
FY138_RS05800	COG0798	PFAM Bile acid sodium symporter
FY138_RS05805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY138_RS05820	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY138_RS05820	COG0321	lipoyl(octanoyl) transferase activity
FY138_RS05825	COG0084	hydrolase, TatD family'
FY138_RS05830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY138_RS05840	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY138_RS05895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY138_RS05900	COG2095	MarC family integral membrane protein
FY138_RS05905	COG0517	IMP dehydrogenase activity
FY138_RS05905	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY138_RS05905	COG0617	tRNA 3'-terminal CCA addition
FY138_RS05915	COG0629	single-stranded DNA binding
FY138_RS05920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY138_RS05930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY138_RS05950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY138_RS05955	COG1121	(ABC) transporter
FY138_RS05975	COG0667	Aldo Keto reductase
FY138_RS05985	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY138_RS06065	COG2239	Acts as a magnesium transporter
FY138_RS06070	COG0243	molybdopterin cofactor binding
FY138_RS06080	COG0242	peptide deformylase activity
FY138_RS06095	COG2202	Pas domain
FY138_RS06095	COG2205	protein histidine kinase activity
FY138_RS06105	COG0321	lipoyl(octanoyl) transferase activity
FY138_RS06110	COG1064	alcohol dehydrogenase
FY138_RS06140	COG1862	Preprotein translocase
FY138_RS06160	COG2124	cytochrome p450
FY138_RS06175	COG0596	Alpha beta hydrolase
FY138_RS06185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY138_RS06190	COG0626	cystathionine gamma-synthase activity
FY138_RS06195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS06200	COG4597	amino acid ABC transporter
FY138_RS06205	COG0765	amino acid transport
FY138_RS06210	COG1126	abc transporter atp-binding protein
FY138_RS06225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY138_RS06240	COG0436	Aminotransferase
FY138_RS06270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY138_RS06280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY138_RS06285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY138_RS06290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY138_RS06305	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY138_RS06310	COG1489	DNA binding
FY138_RS06315	COG0024	Methionine aminopeptidase
FY138_RS06320	COG2003	Belongs to the UPF0758 family
FY138_RS06335	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY138_RS06360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY138_RS06365	COG0546	phosphoglycolate phosphatase activity
FY138_RS06375	COG0114	fumarate hydratase activity
FY138_RS06385	COG0504	CTP synthase activity
FY138_RS06395	COG0149	triose-phosphate isomerase activity
FY138_RS06405	COG0187	DNA topoisomerase II activity
FY138_RS06415	COG0740	serine-type endopeptidase activity
FY138_RS06425	COG0640	Transcriptional regulator
FY138_RS06430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY138_RS06435	COG0745	RESPONSE REGULATOR receiver
FY138_RS06450	COG3264	Mechanosensitive ion channel
FY138_RS06450	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY138_RS06515	COG1127	ABC transporter
FY138_RS06520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY138_RS06525	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_RS06535	COG0280	phosphate acetyltransferase
FY138_RS06535	COG0281	malic enzyme
FY138_RS06545	COG0778	Nitroreductase
FY138_RS06550	COG0823	Involved in the tonB-independent uptake of proteins
FY138_RS06565	COG1368	sulfuric ester hydrolase activity
FY138_RS06590	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY138_RS06610	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY138_RS06630	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY138_RS06645	COG0318	PFAM AMP-dependent synthetase and ligase
FY138_RS06655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY138_RS06655	COG0512	Glutamine amidotransferase of anthranilate synthase
FY138_RS06660	COG0343	queuine tRNA-ribosyltransferase activity
FY138_RS06665	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY138_RS06680	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY138_RS06700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY138_RS06705	COG0134	indole-3-glycerol-phosphate synthase activity
FY138_RS06710	COG0315	cyclic pyranopterin monophosphate synthase activity
FY138_RS06715	COG0303	'Molybdopterin
FY138_RS06720	COG3706	GGDEF domain
FY138_RS06730	COG0475	glutathione-regulated potassium exporter activity
FY138_RS06730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY138_RS06740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY138_RS06750	COG2814	Major facilitator Superfamily
FY138_RS06755	COG0746	molybdenum cofactor guanylyltransferase activity
FY138_RS06760	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY138_RS06765	COG0739	heme binding
FY138_RS06770	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY138_RS06775	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY138_RS06780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY138_RS06785	COG0805	protein transport
FY138_RS06790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY138_RS06795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY138_RS06800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY138_RS06805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY138_RS06810	COG1472	Belongs to the glycosyl hydrolase 3 family
FY138_RS06820	COG0018	arginyl-trna synthetase
FY138_RS06825	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY138_RS06850	COG0525	valine-tRNA ligase activity
FY138_RS06860	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY138_RS07000	COG1525	nuclease
FY138_RS07075	COG3567	Phage-associated protein, HI1409 family
FY138_RS07090	COG5410	chromosome segregation
FY138_RS07125	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY138_RS07310	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY138_RS07315	COG1058	Belongs to the CinA family
FY138_RS07315	COG1546	Belongs to the CinA family
FY138_RS07320	COG0589	response to stress
FY138_RS07325	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY138_RS07340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY138_RS07350	COG0640	Transcriptional regulator
FY138_RS07355	COG1914	H( )-stimulated, divalent metal cation uptake system
FY138_RS07365	COG1132	(ABC) transporter
FY138_RS07370	COG0628	permease
FY138_RS07405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY138_RS07415	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY138_RS07425	COG0302	gtp cyclohydrolase
FY138_RS07430	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY138_RS07435	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY138_RS07445	COG0517	IMP dehydrogenase activity
FY138_RS07445	COG0516	GMP reductase activity
FY138_RS07480	COG1760	l-serine dehydratase
FY138_RS07520	COG0583	DNA-binding transcription factor activity
FY138_RS07535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY138_RS07535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY138_RS07545	COG0347	Belongs to the P(II) protein family
FY138_RS07550	COG0174	glutamine synthetase
FY138_RS07580	COG0697	spore germination
FY138_RS07590	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY138_RS07600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY138_RS07630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY138_RS07640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY138_RS07645	COG2186	Transcriptional regulator
FY138_RS07655	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY138_RS07660	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY138_RS07665	COG3845	ABC transporter
FY138_RS07670	COG1183	phosphatidylcholine synthase activity
FY138_RS07675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY138_RS07680	COG0679	Auxin Efflux Carrier
FY138_RS07685	COG0785	Cytochrome C biogenesis protein
FY138_RS07705	COG1278	Cold shock
FY138_RS07760	COG1136	(ABC) transporter
FY138_RS07760	COG0577	efflux transmembrane transporter activity
FY138_RS07765	COG1136	(ABC) transporter
FY138_RS07765	COG0577	efflux transmembrane transporter activity
FY138_RS07790	COG2151	metal-sulfur cluster biosynthetic enzyme
FY138_RS07795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY138_RS07800	COG0719	Fe-S assembly protein
FY138_RS07805	COG0396	ATPase activity
FY138_RS07810	COG0719	Fe-S assembly protein
FY138_RS07815	COG1104	cysteine desulfurase activity
FY138_RS07820	COG2945	thiolester hydrolase activity
FY138_RS07825	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY138_RS07830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY138_RS07840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY138_RS07845	COG2833	Protein of unknown function (DUF455)
FY138_RS07850	COG0739	heme binding
FY138_RS07855	COG0513	Belongs to the DEAD box helicase family
FY138_RS07880	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY138_RS07890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY138_RS07895	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY138_RS07900	COG0047	phosphoribosylformylglycinamidine synthase activity
FY138_RS07915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY138_RS07920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY138_RS07940	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY138_RS07945	COG2814	Major facilitator Superfamily
FY138_RS07950	COG0483	inositol monophosphate 1-phosphatase activity
FY138_RS07955	COG0483	inositol monophosphate 1-phosphatase activity
FY138_RS07960	COG0037	tRNA processing
FY138_RS07965	COG2066	Belongs to the glutaminase family
FY138_RS07970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY138_RS07975	COG0861	Integral membrane protein TerC family
FY138_RS07990	COG1280	lysine exporter protein (LysE YggA)
FY138_RS08000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY138_RS08005	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY138_RS08015	COG0538	isocitrate dehydrogenase activity
FY138_RS08025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY138_RS08030	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY138_RS08035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_RS08040	COG2313	pseudouridylate synthase activity
FY138_RS08050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS08055	COG4215	(ABC) transporter
FY138_RS08065	COG5425	PFAM Usg family protein
FY138_RS08075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY138_RS08080	COG1522	sequence-specific DNA binding
FY138_RS08085	COG1573	uracil-dna glycosylase
FY138_RS08095	COG2205	protein histidine kinase activity
FY138_RS08095	COG2202	Pas domain
FY138_RS08100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY138_RS08105	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY138_RS08110	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY138_RS08125	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY138_RS08130	COG0842	Transport permease protein
FY138_RS08135	COG1131	(ABC) transporter
FY138_RS08140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY138_RS08140	COG0730	response to heat
FY138_RS08160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY138_RS08165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY138_RS08185	COG0129	dihydroxy-acid dehydratase activity
FY138_RS08190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY138_RS08195	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY138_RS08205	COG3739	integral membrane protein
FY138_RS08210	COG0203	ribosomal protein L17
FY138_RS08215	COG0202	RNA polymerase activity
FY138_RS08220	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY138_RS08225	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY138_RS08230	COG0563	adenylate kinase activity
FY138_RS08235	COG0201	protein transport
FY138_RS08240	COG0200	Binds to the 23S rRNA
FY138_RS08245	COG1841	ribosomal large subunit assembly
FY138_RS08250	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY138_RS08255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY138_RS08260	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY138_RS08265	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY138_RS08270	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY138_RS08275	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY138_RS08280	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY138_RS08285	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY138_RS08290	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY138_RS08295	COG0255	Belongs to the universal ribosomal protein uL29 family
FY138_RS08300	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY138_RS08305	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY138_RS08310	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY138_RS08315	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY138_RS08320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY138_RS08325	COG0089	rRNA binding
FY138_RS08330	COG0088	Forms part of the polypeptide exit tunnel
FY138_RS08335	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY138_RS08340	COG0051	transcription antitermination factor activity, RNA binding
FY138_RS08345	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY138_RS08350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY138_RS08355	COG0049	tRNA binding
FY138_RS08360	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY138_RS08380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY138_RS08385	COG0085	RNA polymerase activity
FY138_RS08390	COG0222	ribosome binding
FY138_RS08395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY138_RS08400	COG0081	regulation of translation
FY138_RS08405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY138_RS08415	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY138_RS08425	COG1086	Polysaccharide biosynthesis protein
FY138_RS08430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY138_RS08435	COG0861	Integral membrane protein TerC family
FY138_RS08440	COG3895	Periplasmic Protein
FY138_RS08460	COG1132	(ABC) transporter
FY138_RS08465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY138_RS08485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY138_RS08520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS08520	COG2205	protein histidine kinase activity
FY138_RS08520	COG2198	Histidine kinase
FY138_RS08520	COG0784	Response regulator, receiver
FY138_RS08525	COG0784	Response regulator, receiver
FY138_RS08530	COG3920	Histidine kinase
FY138_RS08530	COG2202	Pas domain
FY138_RS08535	COG0784	Response regulator, receiver
FY138_RS08540	COG4251	negative regulation of phosphorylation
FY138_RS08555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY138_RS08560	COG1607	acyl-coa hydrolase
FY138_RS08580	COG2910	NAD(P)H-binding
FY138_RS08585	COG1733	regulation of RNA biosynthetic process
FY138_RS08600	COG0556	nucleotide-excision repair
FY138_RS08610	COG2382	esterase
FY138_RS08630	COG0484	heat shock protein binding
FY138_RS08650	COG3706	GGDEF domain
FY138_RS08670	COG1840	ABC-type Fe3 transport system, periplasmic component
FY138_RS08675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY138_RS08690	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY138_RS08700	COG2207	Transcriptional regulator
FY138_RS08705	COG1064	alcohol dehydrogenase
FY138_RS08710	COG1252	NADH dehydrogenase
FY138_RS08715	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY138_RS08720	COG2197	response regulator
FY138_RS08725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY138_RS08760	COG0656	L-ascorbic acid biosynthetic process
FY138_RS08775	COG0440	acetolactate synthase activity
FY138_RS08780	COG0028	Belongs to the TPP enzyme family
FY138_RS08790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY138_RS08795	COG0560	Phosphoserine phosphatase
FY138_RS08795	COG3830	Belongs to the UPF0237 family
FY138_RS08815	COG0330	HflC and HflK could
FY138_RS08820	COG0330	HflC and HflK could
FY138_RS08830	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY138_RS08865	COG0277	FAD linked oxidase domain protein
FY138_RS08870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY138_RS08910	COG1335	isochorismatase
FY138_RS08940	COG2264	protein methyltransferase activity
FY138_RS08945	COG1999	signal sequence binding
FY138_RS08955	COG0835	chemotaxis
FY138_RS08965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY138_RS08970	COG0583	DNA-binding transcription factor activity
FY138_RS08980	COG1247	-acetyltransferase
FY138_RS08990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY138_RS08995	COG0497	DNA recombination
FY138_RS09000	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY138_RS09010	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY138_RS09015	COG0849	cell division
FY138_RS09020	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY138_RS09025	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY138_RS09030	COG0477	Major facilitator Superfamily
FY138_RS09035	COG5001	Diguanylate cyclase
FY138_RS09040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY138_RS09045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY138_RS09050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY138_RS09060	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY138_RS09065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY138_RS09075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY138_RS09090	COG0275	rRNA processing
FY138_RS09095	COG2001	Belongs to the MraZ family
FY138_RS09120	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY138_RS09150	COG4106	trans-aconitate 2-methyltransferase activity
FY138_RS09170	COG2226	methyltransferase
FY138_RS09180	COG2267	carboxylic ester hydrolase activity
FY138_RS09185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY138_RS09200	COG0251	oxidation-reduction process
FY138_RS09215	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_RS09220	COG2814	Major facilitator Superfamily
FY138_RS09250	COG1012	belongs to the aldehyde dehydrogenase family
FY138_RS09255	COG0174	glutamine synthetase
FY138_RS09260	COG0531	amino acid
FY138_RS09270	COG1737	Transcriptional regulator
FY138_RS09275	COG2182	Extracellular solute-binding protein
FY138_RS09290	COG3842	ATPase activity
FY138_RS09350	COG2968	Membrane
FY138_RS09360	COG0432	Pfam Uncharacterised protein family UPF0047
FY138_RS09375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY138_RS09380	COG0358	DNA primase activity
FY138_RS09400	COG0505	Belongs to the CarA family
FY138_RS09405	COG0534	Mate efflux family protein
FY138_RS09420	COG2321	neutral zinc metallopeptidase
FY138_RS09435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY138_RS09445	COG3706	GGDEF domain
FY138_RS09460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY138_RS09470	COG1522	sequence-specific DNA binding
FY138_RS09475	COG0492	ferredoxin-NADP+ reductase activity
FY138_RS09480	COG0583	DNA-binding transcription factor activity
FY138_RS09490	COG1902	pentaerythritol trinitrate reductase activity
FY138_RS09515	COG0387	Pfam Sodium calcium exchanger
FY138_RS09520	COG0436	Aminotransferase
FY138_RS09525	COG2200	EAL domain
FY138_RS09525	COG2199	diguanylate cyclase activity
FY138_RS09540	COG1278	Cold shock
FY138_RS09545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY138_RS09555	COG1846	Transcriptional regulator
FY138_RS09560	COG0745	RESPONSE REGULATOR receiver
FY138_RS09570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY138_RS09590	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY138_RS09600	COG1496	oxidoreductase activity
FY138_RS09615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY138_RS09625	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY138_RS09640	COG0840	transmembrane signaling receptor activity
FY138_RS09645	COG1012	belongs to the aldehyde dehydrogenase family
FY138_RS09650	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY138_RS09655	COG3300	MHYT domain
FY138_RS09655	COG5001	Diguanylate cyclase
FY138_RS09660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY138_RS09665	COG5001	Diguanylate cyclase
FY138_RS09675	COG0193	aminoacyl-tRNA hydrolase activity
FY138_RS09685	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY138_RS09710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY138_RS09720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY138_RS09720	COG2857	Cytochrome c1
FY138_RS09740	COG1132	(ABC) transporter
FY138_RS09750	COG1132	(ABC) transporter
FY138_RS09760	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY138_RS09775	COG0408	coproporphyrinogen oxidase activity
FY138_RS09790	COG0617	tRNA 3'-terminal CCA addition
FY138_RS09805	COG0714	Associated with various cellular activities
FY138_RS09825	COG0454	-acetyltransferase
FY138_RS09840	COG0477	Major facilitator Superfamily
FY138_RS09850	COG0435	Glutathione S-transferase
FY138_RS09855	COG0494	nUDIX hydrolase
FY138_RS09865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY138_RS09870	COG3135	benzoate transporter
FY138_RS09895	COG0740	serine-type endopeptidase activity
FY138_RS09910	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY138_RS09915	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY138_RS09940	COG4175	Glycine betaine
FY138_RS09960	COG1435	thymidine kinase activity
FY138_RS09985	COG4771	TonB-dependent receptor
FY138_RS09985	COG1629	transport
FY138_RS09995	COG0512	Glutamine amidotransferase of anthranilate synthase
FY138_RS09995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY138_RS10010	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY138_RS10020	COG0366	Alpha amylase catalytic
FY138_RS10025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_RS10045	COG1160	GTP binding
FY138_RS10065	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY138_RS10075	COG0024	Methionine aminopeptidase
FY138_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS10105	COG0583	DNA-binding transcription factor activity
FY138_RS10120	COG0402	S-adenosylhomocysteine deaminase activity
FY138_RS10130	COG1304	FMN binding
FY138_RS10140	COG1309	transcriptional regulator
FY138_RS10145	COG1686	Belongs to the peptidase S11 family
FY138_RS10155	COG2351	hydroxyisourate hydrolase activity
FY138_RS10160	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY138_RS10185	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY138_RS10195	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY138_RS10195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS10205	COG0513	Belongs to the DEAD box helicase family
FY138_RS10215	COG2259	Doxx family
FY138_RS10220	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_RS10230	COG2308	Evidence 4 Homologs of previously reported genes of
FY138_RS10240	COG1305	Transglutaminase-like
FY138_RS10265	COG4214	carbohydrate transport
FY138_RS10275	COG4213	ABC transporter substrate-binding protein
FY138_RS10330	COG2948	multi-organism process
FY138_RS10340	COG3701	Conjugal transfer protein
FY138_RS10345	COG3846	protein secretion by the type IV secretion system
FY138_RS10360	COG3451	type IV secretory pathway VirB4
FY138_RS10375	COG4962	Type ii secretion system protein e
FY138_RS10400	COG0583	DNA-binding transcription factor activity
FY138_RS10410	COG1566	PFAM secretion protein HlyD family protein
FY138_RS10425	COG2207	Transcriptional regulator
FY138_RS10430	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS10440	COG0583	DNA-binding transcription factor activity
FY138_RS10450	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY138_RS10460	COG0583	DNA-binding transcription factor activity
FY138_RS10495	COG1192	Involved in chromosome partitioning
FY138_RS10535	COG2814	Major facilitator Superfamily
FY138_RS10545	COG5489	Protein of unknown function (DUF736)
FY138_RS10560	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY138_RS10590	COG1204	response to ionizing radiation
FY138_RS10605	COG0514	ATP-dependent DNA helicase (RecQ)
FY138_RS10655	COG0583	DNA-binding transcription factor activity
FY138_RS10660	COG1902	pentaerythritol trinitrate reductase activity
FY138_RS10665	COG0583	DNA-binding transcription factor activity
FY138_RS10680	COG1335	isochorismatase
FY138_RS10685	COG0583	DNA-binding transcription factor activity
FY138_RS10690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY138_RS10700	COG4584	PFAM Integrase catalytic
FY138_RS10715	COG0840	transmembrane signaling receptor activity
FY138_RS10730	COG0646	methionine synthase
FY138_RS10730	COG1410	methionine synthase
FY138_RS10745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS10775	COG1215	transferase activity, transferring glycosyl groups
FY138_RS10805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY138_RS10820	COG2346	COG2346, Truncated hemoglobins
FY138_RS10840	COG1309	transcriptional regulator
FY138_RS10855	COG0494	nUDIX hydrolase
FY138_RS10865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_RS10870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_RS10900	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY138_RS10905	COG0830	nickel cation binding
FY138_RS10910	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY138_RS10925	COG0804	urea catabolic process
FY138_RS10930	COG1442	glycosyl transferase family 8
FY138_RS10935	COG3755	Protein conserved in bacteria
FY138_RS10945	COG0832	Belongs to the urease beta subunit family
FY138_RS10950	COG3813	Protein conserved in bacteria
FY138_RS10955	COG0831	urea catabolic process
FY138_RS10960	COG0829	nickel cation binding
FY138_RS10980	COG0411	ABC transporter
FY138_RS10990	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY138_RS11010	COG0174	glutamine synthetase
FY138_RS11015	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS11020	COG0784	Response regulator, receiver
FY138_RS11020	COG5002	protein histidine kinase activity
FY138_RS11020	COG2198	Histidine kinase
FY138_RS11035	COG0726	polysaccharide deacetylase
FY138_RS11070	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY138_RS11145	COG0564	pseudouridine synthase activity
FY138_RS11155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY138_RS11165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY138_RS11190	COG0346	lactoylglutathione lyase activity
FY138_RS11200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY138_RS11210	COG2832	Protein of unknown function (DUF454)
FY138_RS11215	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY138_RS11220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_RS11225	COG4558	Periplasmic binding protein
FY138_RS11235	COG3721	Heme iron utilization protein
FY138_RS11250	COG3655	Transcriptional regulator
FY138_RS11275	COG2205	protein histidine kinase activity
FY138_RS11315	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_RS11320	COG4605	iron ion homeostasis
FY138_RS11325	COG4604	ABC transporter, ATP-binding protein
FY138_RS11330	COG0783	Belongs to the Dps family
FY138_RS11345	COG2972	Histidine kinase
FY138_RS11345	COG0840	transmembrane signaling receptor activity
FY138_RS11350	COG0656	L-ascorbic acid biosynthetic process
FY138_RS11355	COG2814	Major facilitator Superfamily
FY138_RS11365	COG0583	DNA-binding transcription factor activity
FY138_RS11370	COG0657	acetylesterase activity
FY138_RS11375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_RS11395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY138_RS11400	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY138_RS11405	COG0288	reversible hydration of carbon dioxide
FY138_RS11415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY138_RS11435	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY138_RS11440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY138_RS11445	COG0778	Nitroreductase
FY138_RS11450	COG2267	carboxylic ester hydrolase activity
FY138_RS11455	COG0251	oxidation-reduction process
FY138_RS11460	COG1335	isochorismatase
FY138_RS11465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS11475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_RS11490	COG1175	transmembrane transport
FY138_RS11495	COG0395	ABC-type sugar transport system, permease component
FY138_RS11500	COG3842	ATPase activity
FY138_RS11505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_RS11515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY138_RS11530	COG4608	Belongs to the ABC transporter superfamily
FY138_RS11535	COG0444	Belongs to the ABC transporter superfamily
FY138_RS11540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS11545	COG0601	transmembrane transport
FY138_RS11600	COG2159	amidohydrolase
FY138_RS11605	COG1960	acyl-CoA dehydrogenase activity
FY138_RS11635	COG0745	RESPONSE REGULATOR receiver
FY138_RS11645	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY138_RS11645	COG1902	pentaerythritol trinitrate reductase activity
FY138_RS11650	COG3842	ATPase activity
FY138_RS11660	COG1840	ABC-type Fe3 transport system, periplasmic component
FY138_RS11665	COG1840	ABC-type Fe3 transport system, periplasmic component
FY138_RS11670	COG0745	RESPONSE REGULATOR receiver
FY138_RS11680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY138_RS11685	COG0583	DNA-binding transcription factor activity
FY138_RS11690	COG1278	Cold shock
FY138_RS11730	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY138_RS11735	COG1309	transcriptional regulator
FY138_RS11740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_RS11745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY138_RS11755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY138_RS11760	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY138_RS11780	COG0583	DNA-binding transcription factor activity
FY138_RS11785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS11790	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY138_RS11795	COG4149	molybdate abc transporter
FY138_RS11800	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY138_RS11815	COG2022	thiamine diphosphate biosynthetic process
FY138_RS11830	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY138_RS11835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY138_RS11845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY138_RS11865	COG1132	(ABC) transporter
FY138_RS11870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY138_RS11915	COG4166	transmembrane transport
FY138_RS11920	COG0601	transmembrane transport
FY138_RS11925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS11940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY138_RS11945	COG3142	Participates in the control of copper homeostasis
FY138_RS11950	COG2814	Major facilitator Superfamily
FY138_RS11965	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS11970	COG1737	Transcriptional regulator
FY138_RS11980	COG3842	ATPase activity
FY138_RS11990	COG0395	ABC-type sugar transport system, permease component
FY138_RS12010	COG2188	Transcriptional regulator
FY138_RS12015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY138_RS12020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY138_RS12025	COG1940	carbohydrate kinase activity
FY138_RS12035	COG0671	phosphoesterase, PA-phosphatase related
FY138_RS12040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY138_RS12045	COG0156	8-amino-7-oxononanoate synthase activity
FY138_RS12055	COG0729	surface antigen
FY138_RS12065	COG0835	chemotaxis
FY138_RS12075	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY138_RS12080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY138_RS12085	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY138_RS12090	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY138_RS12095	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY138_RS12100	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY138_RS12115	COG4974	Belongs to the 'phage' integrase family
FY138_RS12140	COG1280	lysine exporter protein (LysE YggA)
FY138_RS12150	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY138_RS12155	COG0567	Dehydrogenase, E1 component
FY138_RS12160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY138_RS12165	COG0045	succinate-CoA ligase (ADP-forming) activity
FY138_RS12170	COG0039	L-malate dehydrogenase activity
FY138_RS12175	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY138_RS12225	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY138_RS12230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY138_RS12235	COG0181	hydroxymethylbilane synthase activity
FY138_RS12275	COG1872	DUF167
FY138_RS12280	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY138_RS12290	COG1217	gtp-binding protein TYPA
FY138_RS12295	COG0339	signal peptide processing
FY138_RS12300	COG1846	Transcriptional regulator
FY138_RS12310	COG0137	argininosuccinate synthase activity
FY138_RS12320	COG1280	lysine exporter protein (LysE YggA)
FY138_RS12325	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY138_RS12330	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY138_RS12340	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY138_RS12355	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY138_RS12360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY138_RS12365	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY138_RS12375	COG4181	ATPase activity
FY138_RS12385	COG0670	Belongs to the BI1 family
FY138_RS12400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY138_RS12405	COG4133	protoheme IX ABC transporter activity
FY138_RS12410	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY138_RS12415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY138_RS12440	COG2917	probably involved in intracellular septation
FY138_RS12445	COG0552	protein localization to endoplasmic reticulum
FY138_RS12450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY138_RS12455	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY138_RS12470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY138_RS12475	COG1605	Chorismate mutase
FY138_RS12475	COG0287	Prephenate dehydrogenase
FY138_RS12480	COG0228	four-way junction DNA binding
FY138_RS12485	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY138_RS12490	COG0336	Belongs to the RNA methyltransferase TrmD family
FY138_RS12500	COG0335	large ribosomal subunit rRNA binding
FY138_RS12505	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY138_RS12510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_RS12525	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY138_RS12545	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY138_RS12565	COG0488	(ABC) transporter
FY138_RS12575	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY138_RS12585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY138_RS12590	COG0142	geranyltranstransferase activity
FY138_RS12595	COG2885	chlorophyll binding
FY138_RS12600	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY138_RS12605	COG2223	nitrite transmembrane transporter activity
FY138_RS12610	COG1349	DNA-binding transcription factor activity
FY138_RS12615	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY138_RS12620	COG2197	response regulator
FY138_RS12625	COG1132	(ABC) transporter
FY138_RS12635	COG3459	Glycosyltransferase 36 associated
FY138_RS12640	COG1473	amidohydrolase
FY138_RS12650	COG0579	oxidoreductase
FY138_RS12660	COG0129	dihydroxy-acid dehydratase activity
FY138_RS12665	COG2084	Dehydrogenase
FY138_RS12670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_RS12675	COG0277	FAD linked oxidase domain protein
FY138_RS12680	COG2186	Transcriptional regulator
FY138_RS12690	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY138_RS12695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY138_RS12700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY138_RS12705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY138_RS12715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY138_RS12720	COG0495	leucyl-tRNA aminoacylation
FY138_RS12735	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY138_RS12740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY138_RS12755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY138_RS12760	COG1946	Acyl-CoA thioesterase
FY138_RS12765	COG0347	Belongs to the P(II) protein family
FY138_RS12770	COG0004	ammonium transporteR
FY138_RS12775	COG1674	ftsk spoiiie
FY138_RS12780	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY138_RS12795	COG0745	RESPONSE REGULATOR receiver
FY138_RS12805	COG1329	Transcriptional regulator
FY138_RS12815	COG2270	Major facilitator Superfamily
FY138_RS12830	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS12845	COG0494	nUDIX hydrolase
FY138_RS12850	COG2861	carbohydrate metabolic process
FY138_RS12855	COG0793	Belongs to the peptidase S41A family
FY138_RS12865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY138_RS12870	COG0799	negative regulation of ribosome biogenesis
FY138_RS12875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY138_RS12880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY138_RS12885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY138_RS12890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY138_RS12905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY138_RS12910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY138_RS12935	COG0066	3-isopropylmalate dehydratase activity
FY138_RS12940	COG0473	3-isopropylmalate dehydrogenase activity
FY138_RS12945	COG1858	cytochrome C peroxidase
FY138_RS12950	COG1797	cobyrinic acid a,c-diamide synthase activity
FY138_RS12960	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY138_RS13025	COG1492	cobalamin metabolic process
FY138_RS13040	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_RS13045	COG3254	rhamnose metabolic process
FY138_RS13050	COG0246	Mannitol dehydrogenase
FY138_RS13055	COG1063	alcohol dehydrogenase
FY138_RS13080	COG1129	ABC transporter
FY138_RS13085	COG2186	Transcriptional regulator
FY138_RS13090	COG2721	sulfolactate sulfo-lyase activity
FY138_RS13095	COG0138	bifunctional purine biosynthesis protein purh
FY138_RS13105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY138_RS13105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY138_RS13110	COG0501	Belongs to the peptidase M48B family
FY138_RS13130	COG0357	Ribosomal RNA small subunit methyltransferase G
FY138_RS13135	COG0445	tRNA wobble uridine modification
FY138_RS13140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY138_RS13145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY138_RS13150	COG1981	membrane
FY138_RS13155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY138_RS13160	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY138_RS13165	COG0424	maF-like protein
FY138_RS13170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY138_RS13175	COG0237	dephospho-CoA kinase activity
FY138_RS13185	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY138_RS13190	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY138_RS13200	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY138_RS13225	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY138_RS13240	COG0135	phosphoribosylanthranilate isomerase activity
FY138_RS13245	COG0133	tryptophan synthase activity
FY138_RS13250	COG0159	tryptophan synthase activity
FY138_RS13255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY138_RS13270	COG1074	ATP-dependent DNA helicase activity
FY138_RS13280	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY138_RS13285	COG0802	atpase or kinase
FY138_RS13290	COG2205	protein histidine kinase activity
FY138_RS13295	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY138_RS13300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY138_RS13305	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY138_RS13305	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY138_RS13310	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY138_RS13315	COG0642	Histidine kinase
FY138_RS13320	COG0745	RESPONSE REGULATOR receiver
FY138_RS13325	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY138_RS13335	COG1652	LysM domain
FY138_RS13340	COG1072	(Pantothenic acid kinase))
FY138_RS13345	COG0140	phosphoribosyl-ATP diphosphatase activity
FY138_RS13350	COG0107	imidazoleglycerol-phosphate synthase activity
FY138_RS13355	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY138_RS13360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY138_RS13370	COG0131	Imidazoleglycerol-phosphate dehydratase
FY138_RS13375	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY138_RS13380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY138_RS13390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY138_RS13405	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY138_RS13415	COG1643	Atp-dependent helicase
FY138_RS13460	COG1940	carbohydrate kinase activity
FY138_RS13480	COG1072	(Pantothenic acid kinase))
FY138_RS13490	COG1780	Probably involved in ribonucleotide reductase function
FY138_RS13510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY138_RS13540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_RS13550	COG2813	Specifically methylates the guanine in position
FY138_RS13555	COG1185	polyribonucleotide nucleotidyltransferase activity
FY138_RS13560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY138_RS13565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY138_RS13570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY138_RS13575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY138_RS13575	COG3064	Membrane
FY138_RS13590	COG0779	Required for maturation of 30S ribosomal subunits
FY138_RS13595	COG2814	Major facilitator Superfamily
FY138_RS13605	COG2951	lytic endotransglycosylase activity
FY138_RS13610	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY138_RS13620	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY138_RS13625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY138_RS13640	COG2816	NAD+ diphosphatase activity
FY138_RS13645	COG0077	Prephenate dehydratase
FY138_RS13645	COG1605	Chorismate mutase
FY138_RS13650	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY138_RS13655	COG3474	cytochrome
FY138_RS13665	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY138_RS13670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY138_RS13675	COG1278	Cold shock
FY138_RS13680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY138_RS13690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY138_RS13690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY138_RS13695	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY138_RS13725	COG2900	Belongs to the SlyX family
FY138_RS13735	COG0484	heat shock protein binding
FY138_RS13740	COG0443	Heat shock 70 kDa protein
FY138_RS13755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY138_RS13760	COG1744	ABC transporter substrate-binding protein PnrA-like
FY138_RS13765	COG3845	ABC transporter
FY138_RS13770	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY138_RS13775	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY138_RS13780	COG0295	cytidine deaminase activity
FY138_RS13785	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY138_RS13790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY138_RS13795	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY138_RS13805	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY138_RS13810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY138_RS13815	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY138_RS13825	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY138_RS13830	COG1845	cytochrome c oxidase, subunit III
FY138_RS13835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY138_RS13840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY138_RS13845	COG0477	Major facilitator Superfamily
FY138_RS13850	COG0067	glutamate synthase
FY138_RS13850	COG0070	glutamate synthase
FY138_RS13850	COG0069	glutamate synthase activity
FY138_RS13855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY138_RS13870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY138_RS13880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY138_RS13910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_RS13930	COG0848	biopolymer transport protein
FY138_RS13940	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY138_RS13955	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY138_RS13960	COG3454	Phosphonate metabolism
FY138_RS13965	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY138_RS13970	COG3639	organic phosphonate transmembrane transporter activity
FY138_RS13975	COG3639	organic phosphonate transmembrane transporter activity
FY138_RS13985	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY138_RS13995	COG4778	phosphonate C-P lyase system protein PhnL
FY138_RS14000	COG4107	phosphonate C-P lyase system protein PhnK
FY138_RS14005	COG3627	carbon phosphorus lyase activity
FY138_RS14010	COG3626	phosphonate metabolism
FY138_RS14015	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY138_RS14020	COG3624	Phosphonate C-P lyase system protein PhnG
FY138_RS14025	COG2188	Transcriptional regulator
FY138_RS14030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY138_RS14035	COG0837	glucose binding
FY138_RS14040	COG1803	Methylglyoxal synthase
FY138_RS14045	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY138_RS14050	COG4166	transmembrane transport
FY138_RS14055	COG4174	ABC transporter (Permease)
FY138_RS14060	COG4239	(ABC) transporter, permease
FY138_RS14065	COG4172	Belongs to the ABC transporter superfamily
FY138_RS14070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS14075	COG0174	glutamine synthetase
FY138_RS14080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS14085	COG3265	gluconokinase activity
FY138_RS14090	COG1174	glycine betaine transport
FY138_RS14095	COG1125	glycine betaine transport
FY138_RS14100	COG1174	glycine betaine transport
FY138_RS14105	COG1732	Glycine betaine
FY138_RS14115	COG1959	2 iron, 2 sulfur cluster binding
FY138_RS14120	COG1840	ABC-type Fe3 transport system, periplasmic component
FY138_RS14130	COG4269	membrane
FY138_RS14145	COG0697	spore germination
FY138_RS14160	COG0791	NLP P60 protein
FY138_RS14170	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY138_RS14175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY138_RS14210	COG4964	Belongs to the GSP D family
FY138_RS14255	COG3422	double-strand break repair
FY138_RS14260	COG3757	hydrolase, family 25
FY138_RS14265	COG0697	spore germination
FY138_RS14270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY138_RS14285	COG0492	ferredoxin-NADP+ reductase activity
FY138_RS14300	COG0481	GTPase activity
FY138_RS14305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY138_RS14320	COG1396	sequence-specific DNA binding
FY138_RS14335	COG2169	Transcriptional regulator
FY138_RS14335	COG1917	Cupin 2, conserved barrel domain protein
FY138_RS14340	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY138_RS14365	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY138_RS14370	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY138_RS14375	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY138_RS14385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY138_RS14390	COG0072	phenylalanine-tRNA ligase activity
FY138_RS14390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY138_RS14395	COG0667	Aldo Keto reductase
FY138_RS14415	COG4977	sequence-specific DNA binding
FY138_RS14440	COG1570	exodeoxyribonuclease VII activity
FY138_RS14445	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_RS14455	COG1846	Transcriptional regulator
FY138_RS14465	COG2309	aminopeptidase activity
FY138_RS14475	COG1393	Belongs to the ArsC family
FY138_RS14495	COG1309	transcriptional regulator
FY138_RS14505	COG0519	Catalyzes the synthesis of GMP from XMP
FY138_RS14505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY138_RS14520	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY138_RS14550	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY138_RS14560	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY138_RS14570	COG1968	undecaprenyl-diphosphatase activity
FY138_RS14585	COG0284	orotidine-5'-phosphate decarboxylase activity
FY138_RS14595	COG3963	phosphatidate phosphatase activity
FY138_RS14605	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY138_RS14610	COG0792	nuclease activity
FY138_RS14625	COG1175	transmembrane transport
FY138_RS14630	COG0395	ABC-type sugar transport system, permease component
FY138_RS14635	COG3842	ATPase activity
FY138_RS14645	COG0189	ligase activity
FY138_RS14655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY138_RS14660	COG1280	lysine exporter protein (LysE YggA)
FY138_RS14665	COG0756	dUTP diphosphatase activity
FY138_RS14670	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY138_RS14675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY138_RS14690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY138_RS14695	COG2226	methyltransferase
FY138_RS14700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY138_RS14705	COG1024	Enoyl-CoA hydratase
FY138_RS14710	COG0268	Binds directly to 16S ribosomal RNA
FY138_RS14715	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY138_RS14730	COG0640	Transcriptional regulator
FY138_RS14765	COG4178	(ABC) transporter
FY138_RS14790	COG1082	Xylose isomerase domain protein TIM barrel
FY138_RS14795	COG0572	uridine kinase
FY138_RS14805	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS14810	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS14815	COG1129	ABC transporter
FY138_RS14835	COG3284	Transcriptional regulator
FY138_RS14840	COG1063	alcohol dehydrogenase
FY138_RS14850	COG0110	maltose O-acetyltransferase activity
FY138_RS14855	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY138_RS14880	COG0488	(ABC) transporter
FY138_RS14885	COG5265	(ABC) transporter
FY138_RS14890	COG3181	Tripartite tricarboxylate transporter family receptor
FY138_RS14895	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY138_RS14905	COG3237	CsbD-like
FY138_RS14925	COG0395	ABC-type sugar transport system, permease component
FY138_RS14930	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY138_RS14940	COG0483	inositol monophosphate 1-phosphatase activity
FY138_RS14950	COG0405	Gamma-glutamyltransferase
FY138_RS14955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS14960	COG0601	transmembrane transport
FY138_RS14965	COG0747	negative chemotaxis
FY138_RS14970	COG2186	Transcriptional regulator
FY138_RS14980	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_RS14985	COG4172	Belongs to the ABC transporter superfamily
FY138_RS14990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS14995	COG0601	transmembrane transport
FY138_RS15000	COG0747	negative chemotaxis
FY138_RS15005	COG2186	Transcriptional regulator
FY138_RS15015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_RS15020	COG2223	nitrite transmembrane transporter activity
FY138_RS15030	COG3383	formate dehydrogenase (NAD+) activity
FY138_RS15050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY138_RS15065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY138_RS15075	COG0765	amino acid transport
FY138_RS15080	COG0765	amino acid transport
FY138_RS15085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS15100	COG3938	Belongs to the proline racemase family
FY138_RS15110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS15120	COG0765	amino acid transport
FY138_RS15135	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY138_RS15140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_RS15150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY138_RS15155	COG0784	Response regulator, receiver
FY138_RS15170	COG0842	Transport permease protein
FY138_RS15175	COG0842	Transport permease protein
FY138_RS15175	COG1129	ABC transporter
FY138_RS15180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_RS15185	COG1486	melibiose metabolic process
FY138_RS15190	COG4172	Belongs to the ABC transporter superfamily
FY138_RS15195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS15200	COG0601	transmembrane transport
FY138_RS15205	COG0747	negative chemotaxis
FY138_RS15210	COG1486	melibiose metabolic process
FY138_RS15235	COG1940	carbohydrate kinase activity
FY138_RS15240	COG2182	Extracellular solute-binding protein
FY138_RS15245	COG1175	transmembrane transport
FY138_RS15250	COG0395	ABC-type sugar transport system, permease component
FY138_RS15255	COG0165	Argininosuccinate lyase
FY138_RS15260	COG3842	ATPase activity
FY138_RS15265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_RS15270	COG3119	arylsulfatase activity
FY138_RS15280	COG0583	DNA-binding transcription factor activity
FY138_RS15285	COG1120	ATPase activity
FY138_RS15290	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_RS15295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_RS15305	COG4774	siderophore transport
FY138_RS15320	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY138_RS15335	COG2205	protein histidine kinase activity
FY138_RS15340	COG0745	RESPONSE REGULATOR receiver
FY138_RS15345	COG1566	PFAM secretion protein HlyD family protein
FY138_RS15360	COG1392	Phosphate transport regulator
FY138_RS15365	COG0306	phosphate transporter
FY138_RS15370	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY138_RS15380	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY138_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS15395	COG3300	MHYT domain
FY138_RS15395	COG5001	Diguanylate cyclase
FY138_RS15415	COG2186	Transcriptional regulator
FY138_RS15420	COG0601	transmembrane transport
FY138_RS15425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS15430	COG0444	Belongs to the ABC transporter superfamily
FY138_RS15440	COG3842	ATPase activity
FY138_RS15445	COG0395	ABC-type sugar transport system, permease component
FY138_RS15460	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY138_RS15460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY138_RS15465	COG1609	Transcriptional regulator
FY138_RS15475	COG0210	DNA helicase
FY138_RS15480	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY138_RS15485	COG1088	dTDP-glucose 4,6-dehydratase activity
FY138_RS15490	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY138_RS15495	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY138_RS15510	COG3754	Rhamnan synthesis protein F
FY138_RS15515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY138_RS15535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY138_RS15545	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY138_RS15550	COG1216	Glycosyl transferase, family 2
FY138_RS15550	COG1442	glycosyl transferase family 8
FY138_RS15565	COG1132	(ABC) transporter
FY138_RS15575	COG0583	DNA-binding transcription factor activity
FY138_RS15580	COG0667	Aldo Keto reductase
FY138_RS15600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY138_RS15615	COG0300	oxidoreductase activity
FY138_RS15620	COG0584	glycerophosphoryl diester phosphodiesterase
FY138_RS15625	COG1940	carbohydrate kinase activity
FY138_RS15635	COG3712	iron ion homeostasis
FY138_RS15640	COG4774	siderophore transport
FY138_RS15645	COG2814	Major facilitator Superfamily
FY138_RS15665	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY138_RS15675	COG3842	ATPase activity
FY138_RS15680	COG1175	transmembrane transport
FY138_RS15685	COG0395	ABC-type sugar transport system, permease component
FY138_RS15690	COG1609	Transcriptional regulator
FY138_RS15700	COG0673	inositol 2-dehydrogenase activity
FY138_RS15705	COG1082	Xylose isomerase domain protein TIM barrel
FY138_RS15720	COG1609	Transcriptional regulator
FY138_RS15725	COG0183	Belongs to the thiolase family
FY138_RS15730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY138_RS15740	COG1414	Transcriptional regulator
FY138_RS15755	COG0583	DNA-binding transcription factor activity
FY138_RS15765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY138_RS15770	COG3485	protocatechuate 3,4-dioxygenase
FY138_RS15775	COG3485	protocatechuate 3,4-dioxygenase
FY138_RS15780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY138_RS15785	COG0765	amino acid transport
FY138_RS15790	COG0765	amino acid transport
FY138_RS15795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS15800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS15805	COG1126	abc transporter atp-binding protein
FY138_RS15810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY138_RS15815	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY138_RS15840	COG4172	Belongs to the ABC transporter superfamily
FY138_RS15845	COG0747	negative chemotaxis
FY138_RS15855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS15870	COG0683	leucine binding
FY138_RS15885	COG0411	ABC transporter
FY138_RS15900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_RS15905	COG3962	Belongs to the TPP enzyme family
FY138_RS15915	COG3718	enzyme involved in inositol metabolism
FY138_RS15925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY138_RS15930	COG1609	Transcriptional regulator
FY138_RS15935	COG1846	Transcriptional regulator
FY138_RS15945	COG0523	cobalamin synthesis protein
FY138_RS15985	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY138_RS16005	COG0800	Aldolase
FY138_RS16010	COG2954	triphosphatase activity
FY138_RS16020	COG1054	Belongs to the UPF0176 family
FY138_RS16025	COG3300	MHYT domain
FY138_RS16025	COG5001	Diguanylate cyclase
FY138_RS16035	COG2011	ABC-type metal ion transport system permease component
FY138_RS16040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY138_RS16045	COG0778	Nitroreductase
FY138_RS16055	COG2115	Belongs to the xylose isomerase family
FY138_RS16060	COG1070	Carbohydrate kinase
FY138_RS16065	COG1609	Transcriptional regulator
FY138_RS16085	COG1309	transcriptional regulator
FY138_RS16090	COG1253	flavin adenine dinucleotide binding
FY138_RS16095	COG3273	potassium ion transport
FY138_RS16095	COG0471	metal ion transport
FY138_RS16100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY138_RS16105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY138_RS16110	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY138_RS16120	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY138_RS16125	COG1121	(ABC) transporter
FY138_RS16130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY138_RS16135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY138_RS16145	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS16150	COG1414	Transcriptional regulator
FY138_RS16155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY138_RS16175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY138_RS16225	COG0395	ABC-type sugar transport system, permease component
FY138_RS16230	COG1175	transmembrane transport
FY138_RS16240	COG2390	Transcriptional regulator
FY138_RS16245	COG4172	Belongs to the ABC transporter superfamily
FY138_RS16250	COG1473	amidohydrolase
FY138_RS16260	COG0601	transmembrane transport
FY138_RS16265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS16275	COG0693	protein deglycase activity
FY138_RS16280	COG0154	amidase activity
FY138_RS16285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS16295	COG0747	negative chemotaxis
FY138_RS16300	COG0583	DNA-binding transcription factor activity
FY138_RS16305	COG4608	Belongs to the ABC transporter superfamily
FY138_RS16310	COG0444	Belongs to the ABC transporter superfamily
FY138_RS16315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS16320	COG0601	transmembrane transport
FY138_RS16325	COG0747	negative chemotaxis
FY138_RS16340	COG1473	amidohydrolase
FY138_RS16345	COG2814	Major facilitator Superfamily
FY138_RS16350	COG0583	DNA-binding transcription factor activity
FY138_RS16355	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY138_RS16365	COG3842	ATPase activity
FY138_RS16375	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_RS16385	COG1609	Transcriptional regulator
FY138_RS16390	COG0583	DNA-binding transcription factor activity
FY138_RS16395	COG1960	acyl-CoA dehydrogenase activity
FY138_RS16400	COG4774	siderophore transport
FY138_RS16400	COG1629	transport
FY138_RS16410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS16420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_RS16425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_RS16435	COG2375	cellular response to nickel ion
FY138_RS16445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY138_RS16450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY138_RS16450	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY138_RS16460	COG1169	isochorismate synthase
FY138_RS16465	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY138_RS16470	COG1535	isochorismatase
FY138_RS16470	COG3433	isochorismatase activity
FY138_RS16475	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS16490	COG3005	denitrification pathway
FY138_RS16500	COG0243	molybdopterin cofactor binding
FY138_RS16515	COG4459	periplasmic nitrate reductase
FY138_RS16550	COG0826	peptidase U32
FY138_RS16560	COG3189	MarR family transcriptional regulator
FY138_RS16565	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY138_RS16600	COG3256	nitric oxide reductase
FY138_RS16605	COG0714	Associated with various cellular activities
FY138_RS16665	COG0673	inositol 2-dehydrogenase activity
FY138_RS16675	COG1609	Transcriptional regulator
FY138_RS16680	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS16685	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS16690	COG1129	ABC transporter
FY138_RS16695	COG1879	ABC-type sugar transport system periplasmic component
FY138_RS16705	COG0583	DNA-binding transcription factor activity
FY138_RS16720	COG1609	Transcriptional regulator
FY138_RS16725	COG0673	inositol 2-dehydrogenase activity
FY138_RS16735	COG1653	transport
FY138_RS16740	COG1175	transmembrane transport
FY138_RS16745	COG0395	ABC-type sugar transport system, permease component
FY138_RS16750	COG3842	ATPase activity
FY138_RS16765	COG1253	flavin adenine dinucleotide binding
FY138_RS16790	COG3300	MHYT domain
FY138_RS16790	COG5001	Diguanylate cyclase
FY138_RS16920	COG0477	Major facilitator Superfamily
FY138_RS16940	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS16950	COG1879	ABC-type sugar transport system periplasmic component
FY138_RS16960	COG1063	alcohol dehydrogenase
FY138_RS16975	COG1136	(ABC) transporter
FY138_RS16990	COG1309	transcriptional regulator
FY138_RS17015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY138_RS17025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY138_RS17025	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY138_RS17035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS17040	COG0047	phosphoribosylformylglycinamidine synthase activity
FY138_RS17050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_RS17055	COG1012	belongs to the aldehyde dehydrogenase family
FY138_RS17060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS17070	COG3448	diguanylate cyclase activity
FY138_RS17070	COG4175	Glycine betaine
FY138_RS17080	COG4176	ABC-type proline glycine betaine transport system permease component
FY138_RS17085	COG3938	Belongs to the proline racemase family
FY138_RS17090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY138_RS17095	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS17125	COG1733	regulation of RNA biosynthetic process
FY138_RS17175	COG0477	Major facilitator Superfamily
FY138_RS17185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY138_RS17195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY138_RS17210	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS17220	COG0395	ABC-type sugar transport system, permease component
FY138_RS17245	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS17250	COG1349	DNA-binding transcription factor activity
FY138_RS17255	COG1069	ribulokinase activity
FY138_RS17275	COG1940	carbohydrate kinase activity
FY138_RS17290	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_RS17295	COG1177	transmembrane transport
FY138_RS17305	COG3842	ATPase activity
FY138_RS17365	COG0577	efflux transmembrane transporter activity
FY138_RS17365	COG1136	(ABC) transporter
FY138_RS17390	COG1845	cytochrome c oxidase, subunit III
FY138_RS17395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY138_RS17400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY138_RS17405	COG3474	cytochrome
FY138_RS17435	COG3842	ATPase activity
FY138_RS17440	COG0395	ABC-type sugar transport system, permease component
FY138_RS17445	COG1175	transmembrane transport
FY138_RS17450	COG1653	transport
FY138_RS17455	COG1012	belongs to the aldehyde dehydrogenase family
FY138_RS17460	COG1024	Enoyl-CoA hydratase
FY138_RS17480	COG4702	Belongs to the UPF0303 family
FY138_RS17485	COG4774	siderophore transport
FY138_RS17485	COG1629	transport
FY138_RS17490	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY138_RS17495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_RS17500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_RS17505	COG1120	ATPase activity
FY138_RS17520	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY138_RS17530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY138_RS17535	COG1177	transmembrane transport
FY138_RS17540	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_RS17545	COG3842	ATPase activity
FY138_RS17570	COG1335	isochorismatase
FY138_RS17585	COG0583	DNA-binding transcription factor activity
FY138_RS17590	COG2318	DinB family
FY138_RS17615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY138_RS17645	COG0778	Nitroreductase
FY138_RS17665	COG0277	FAD linked oxidase domain protein
FY138_RS17685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS17690	COG4172	Belongs to the ABC transporter superfamily
FY138_RS17700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS17710	COG0431	NADPH-dependent FMN reductase
FY138_RS17730	COG1522	sequence-specific DNA binding
FY138_RS17735	COG2376	Dihydroxyacetone kinase
FY138_RS17745	COG4221	oxidoreductase activity
FY138_RS17750	COG0625	glutathione transferase activity
FY138_RS17760	COG1566	PFAM secretion protein HlyD family protein
FY138_RS17770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY138_RS17775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY138_RS17790	COG0534	Mate efflux family protein
FY138_RS17825	COG1733	regulation of RNA biosynthetic process
FY138_RS17835	COG1136	(ABC) transporter
FY138_RS17835	COG0577	efflux transmembrane transporter activity
FY138_RS17840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_RS17850	COG0745	RESPONSE REGULATOR receiver
FY138_RS17870	COG3209	COG3209 Rhs family protein
FY138_RS17900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS17925	COG3177	Filamentation induced by cAMP protein fic
FY138_RS17940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS17945	COG4597	amino acid ABC transporter
FY138_RS17950	COG0765	amino acid transport
FY138_RS17975	COG0747	negative chemotaxis
FY138_RS17980	COG0601	transmembrane transport
FY138_RS17985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS17990	COG0444	Belongs to the ABC transporter superfamily
FY138_RS17995	COG4608	Belongs to the ABC transporter superfamily
FY138_RS18015	COG4213	ABC transporter substrate-binding protein
FY138_RS18020	COG1129	ABC transporter
FY138_RS18025	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS18040	COG0667	Aldo Keto reductase
FY138_RS18065	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS18070	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS18075	COG1129	ABC transporter
FY138_RS18085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS18095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS18105	COG0747	negative chemotaxis
FY138_RS18110	COG0747	negative chemotaxis
FY138_RS18115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS18125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS18130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS18135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY138_RS18145	COG0405	Gamma-glutamyltransferase
FY138_RS18175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_RS18180	COG0436	Aminotransferase
FY138_RS18195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS18200	COG0765	amino acid transport
FY138_RS18210	COG1126	abc transporter atp-binding protein
FY138_RS18220	COG2186	Transcriptional regulator
FY138_RS18240	COG1846	Transcriptional regulator
FY138_RS18245	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS18255	COG0583	DNA-binding transcription factor activity
FY138_RS18290	COG0583	DNA-binding transcription factor activity
FY138_RS18310	COG1280	lysine exporter protein (LysE YggA)
FY138_RS18315	COG3920	Histidine kinase
FY138_RS18340	COG0753	catalase activity
FY138_RS18360	COG1278	Cold shock
FY138_RS18400	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS18405	COG1902	pentaerythritol trinitrate reductase activity
FY138_RS18410	COG4221	oxidoreductase activity
FY138_RS18415	COG1309	transcriptional regulator
FY138_RS18430	COG1280	lysine exporter protein (LysE YggA)
FY138_RS18440	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY138_RS18480	COG0741	lytic transglycosylase activity
FY138_RS18480	COG1196	nuclear chromosome segregation
FY138_RS18480	COG0739	heme binding
FY138_RS18485	COG0542	response to heat
FY138_RS18495	COG2890	protein-(glutamine-N5) methyltransferase activity
FY138_RS18500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY138_RS18510	COG0527	aspartate kinase activity
FY138_RS18525	COG0019	diaminopimelate decarboxylase activity
FY138_RS18540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY138_RS18560	COG0784	Response regulator, receiver
FY138_RS18575	COG1522	sequence-specific DNA binding
FY138_RS18585	COG1116	anion transmembrane transporter activity
FY138_RS18590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_RS18595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY138_RS18600	COG1012	belongs to the aldehyde dehydrogenase family
FY138_RS18605	COG0583	DNA-binding transcription factor activity
FY138_RS18610	COG0435	Glutathione S-transferase
FY138_RS18625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY138_RS18630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_RS18635	COG0189	ligase activity
FY138_RS18655	COG0693	protein deglycase activity
FY138_RS18685	COG3685	Protein conserved in bacteria
FY138_RS18690	COG4993	Dehydrogenase
FY138_RS18705	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS18710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY138_RS18755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS18770	COG0246	Mannitol dehydrogenase
FY138_RS18775	COG4608	Belongs to the ABC transporter superfamily
FY138_RS18780	COG0444	Belongs to the ABC transporter superfamily
FY138_RS18785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS18790	COG0601	transmembrane transport
FY138_RS18795	COG0747	negative chemotaxis
FY138_RS18805	COG4221	oxidoreductase activity
FY138_RS18835	COG0539	negative regulation of cytoplasmic translation
FY138_RS18840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY138_RS18870	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY138_RS18875	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY138_RS18905	COG1294	oxidase, subunit
FY138_RS18915	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY138_RS18920	COG4988	ABC transporter
FY138_RS18930	COG1063	alcohol dehydrogenase
FY138_RS18935	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS18940	COG2084	Dehydrogenase
FY138_RS18950	COG1522	sequence-specific DNA binding
FY138_RS18955	COG1794	racemase activity, acting on amino acids and derivatives
FY138_RS18970	COG0058	SHG alpha-glucan phosphorylase activity
FY138_RS18975	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY138_RS18980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY138_RS18985	COG0297	glycogen (starch) synthase activity
FY138_RS18990	COG0033	Phosphoglucomutase
FY138_RS18995	COG1523	belongs to the glycosyl hydrolase 13 family
FY138_RS19025	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY138_RS19025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY138_RS19040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS19045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY138_RS19065	COG1215	transferase activity, transferring glycosyl groups
FY138_RS19070	COG2327	Polysaccharide pyruvyl transferase
FY138_RS19075	COG0463	Glycosyl transferase, family 2
FY138_RS19080	COG2244	polysaccharide biosynthetic process
FY138_RS19085	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY138_RS19090	COG2273	Hydrolase Family 16
FY138_RS19095	COG0438	transferase activity, transferring glycosyl groups
FY138_RS19100	COG1215	transferase activity, transferring glycosyl groups
FY138_RS19105	COG1215	transferase activity, transferring glycosyl groups
FY138_RS19110	COG1215	transferase activity, transferring glycosyl groups
FY138_RS19115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY138_RS19120	COG3206	protein involved in exopolysaccharide biosynthesis
FY138_RS19120	COG0489	protein tyrosine kinase activity
FY138_RS19125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY138_RS19130	COG4191	Histidine kinase
FY138_RS19130	COG0784	Response regulator, receiver
FY138_RS19145	COG4176	ABC-type proline glycine betaine transport system permease component
FY138_RS19150	COG3448	diguanylate cyclase activity
FY138_RS19150	COG4175	Glycine betaine
FY138_RS19165	COG0564	pseudouridine synthase activity
FY138_RS19170	COG0500	methyltransferase
FY138_RS19180	COG2133	pyrroloquinoline quinone binding
FY138_RS19190	COG2197	response regulator
FY138_RS19195	COG4585	Histidine kinase
FY138_RS19200	COG1879	ABC-type sugar transport system periplasmic component
FY138_RS19205	COG1129	ABC transporter
FY138_RS19210	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS19220	COG3386	PFAM SMP-30 Gluconolaconase
FY138_RS19225	COG2137	regulation of response to DNA damage stimulus
FY138_RS19230	COG3474	cytochrome
FY138_RS19240	COG1120	ATPase activity
FY138_RS19255	COG4774	siderophore transport
FY138_RS19260	COG0583	DNA-binding transcription factor activity
FY138_RS19270	COG2194	sulfuric ester hydrolase activity
FY138_RS19285	COG0477	Major facilitator Superfamily
FY138_RS19305	COG0673	inositol 2-dehydrogenase activity
FY138_RS19310	COG0697	spore germination
FY138_RS19320	COG0010	Belongs to the arginase family
FY138_RS19335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY138_RS19340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY138_RS19345	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY138_RS19350	COG0156	8-amino-7-oxononanoate synthase activity
FY138_RS19355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY138_RS19405	COG0671	phosphoesterase, PA-phosphatase related
FY138_RS19410	COG0745	RESPONSE REGULATOR receiver
FY138_RS19415	COG2205	protein histidine kinase activity
FY138_RS19425	COG0477	Major facilitator Superfamily
FY138_RS19430	COG0583	DNA-binding transcription factor activity
FY138_RS19450	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY138_RS19465	COG0346	lactoylglutathione lyase activity
FY138_RS19470	COG0583	DNA-binding transcription factor activity
FY138_RS19500	COG1215	transferase activity, transferring glycosyl groups
FY138_RS19520	COG0840	transmembrane signaling receptor activity
FY138_RS19535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_RS19550	COG2828	Protein conserved in bacteria
FY138_RS19555	COG0583	DNA-binding transcription factor activity
FY138_RS19560	COG1846	Transcriptional regulator
FY138_RS19585	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS19590	COG1309	transcriptional regulator
FY138_RS19595	COG2207	Transcriptional regulator
FY138_RS19610	COG1566	PFAM secretion protein HlyD family protein
FY138_RS19630	COG0395	ABC-type sugar transport system, permease component
FY138_RS19635	COG4166	transmembrane transport
FY138_RS19640	COG0601	transmembrane transport
FY138_RS19645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS19650	COG4172	Belongs to the ABC transporter superfamily
FY138_RS19690	COG0402	S-adenosylhomocysteine deaminase activity
FY138_RS19695	COG1228	amidohydrolase
FY138_RS19700	COG2986	histidine ammonia-lyase
FY138_RS19710	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY138_RS19740	COG1192	Involved in chromosome partitioning
FY138_RS19745	COG1475	DNA binding
FY138_RS19750	COG1414	Transcriptional regulator
FY138_RS19770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY138_RS19775	COG4771	TonB-dependent receptor
FY138_RS19785	COG0366	Alpha amylase catalytic
FY138_RS19790	COG4770	biotin carboxylase activity
FY138_RS19795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY138_RS19800	COG4336	lyase activity
FY138_RS19805	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY138_RS19810	COG1914	H( )-stimulated, divalent metal cation uptake system
FY138_RS19815	COG1802	Transcriptional regulator
FY138_RS19820	COG3707	response regulator
FY138_RS19830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY138_RS19835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_RS19840	COG1116	anion transmembrane transporter activity
FY138_RS19845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY138_RS19855	COG0243	molybdopterin cofactor binding
FY138_RS19860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY138_RS19860	COG1648	precorrin-2 dehydrogenase activity
FY138_RS19875	COG3842	ATPase activity
FY138_RS19890	COG0395	ABC-type sugar transport system, permease component
FY138_RS19905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY138_RS19920	COG0071	Belongs to the small heat shock protein (HSP20) family
FY138_RS19965	COG1879	ABC-type sugar transport system periplasmic component
FY138_RS19970	COG1129	ABC transporter
FY138_RS19975	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS19985	COG0667	Aldo Keto reductase
FY138_RS19990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY138_RS19995	COG1830	Aldolase
FY138_RS20000	COG1070	Carbohydrate kinase
FY138_RS20005	COG0840	transmembrane signaling receptor activity
FY138_RS20020	COG0436	Aminotransferase
FY138_RS20030	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY138_RS20040	COG3842	ATPase activity
FY138_RS20045	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY138_RS20050	COG1984	allophanate hydrolase subunit 2
FY138_RS20055	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY138_RS20065	COG0439	Biotin carboxylase
FY138_RS20070	COG0511	ligase activity, forming carbon-carbon bonds
FY138_RS20075	COG0697	spore germination
FY138_RS20080	COG0697	spore germination
FY138_RS20095	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY138_RS20110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_RS20115	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS20120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY138_RS20125	COG4221	oxidoreductase activity
FY138_RS20130	COG0765	amino acid transport
FY138_RS20135	COG0765	amino acid transport
FY138_RS20145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS20150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY138_RS20155	COG1063	alcohol dehydrogenase
FY138_RS20170	COG1304	FMN binding
FY138_RS20195	COG3842	ATPase activity
FY138_RS20205	COG0395	ABC-type sugar transport system, permease component
FY138_RS20210	COG1175	transmembrane transport
FY138_RS20225	COG2186	Transcriptional regulator
FY138_RS20230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY138_RS20235	COG0488	(ABC) transporter
FY138_RS20250	COG2307	Protein conserved in bacteria
FY138_RS20250	COG2308	Evidence 4 Homologs of previously reported genes of
FY138_RS20290	COG1454	alcohol dehydrogenase
FY138_RS20295	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY138_RS20305	COG0747	negative chemotaxis
FY138_RS20310	COG0601	transmembrane transport
FY138_RS20315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS20325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_RS20370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY138_RS20395	COG1082	Xylose isomerase domain protein TIM barrel
FY138_RS20400	COG0673	inositol 2-dehydrogenase activity
FY138_RS20405	COG1082	Xylose isomerase domain protein TIM barrel
FY138_RS20425	COG1609	Transcriptional regulator
FY138_RS20430	COG2986	histidine ammonia-lyase
FY138_RS20435	COG0517	IMP dehydrogenase activity
FY138_RS20435	COG4175	Glycine betaine
FY138_RS20440	COG4176	ABC-type proline glycine betaine transport system permease component
FY138_RS20480	COG2186	Transcriptional regulator
FY138_RS20485	COG1027	Aspartate ammonia-lyase
FY138_RS20495	COG0252	asparaginase activity
FY138_RS20505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY138_RS20515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY138_RS20520	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY138_RS20525	COG2205	protein histidine kinase activity
FY138_RS20540	COG0067	glutamate synthase
FY138_RS20540	COG0070	glutamate synthase
FY138_RS20540	COG0069	glutamate synthase activity
FY138_RS20555	COG2205	protein histidine kinase activity
FY138_RS20570	COG2951	lytic endotransglycosylase activity
FY138_RS20575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY138_RS20600	COG0330	HflC and HflK could
FY138_RS20605	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY138_RS20610	COG0737	Belongs to the 5'-nucleotidase family
FY138_RS20620	COG5310	Homospermidine synthase
FY138_RS20630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY138_RS20635	COG1164	Oligoendopeptidase f
FY138_RS20640	COG2204	response regulator
FY138_RS20645	COG3108	Peptidase M15
FY138_RS20650	COG0469	pyruvate kinase activity
FY138_RS20670	COG3750	Belongs to the UPF0335 family
FY138_RS20675	COG0457	Tetratricopeptide repeat
FY138_RS20680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY138_RS20685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY138_RS20690	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY138_RS20720	COG0483	inositol monophosphate 1-phosphatase activity
FY138_RS20740	COG1132	(ABC) transporter
FY138_RS20745	COG0254	rRNA binding
FY138_RS20770	COG3588	fructose-bisphosphate aldolase
FY138_RS20775	COG0126	phosphoglycerate kinase activity
FY138_RS20780	COG3263	regulation of cellular component size
FY138_RS20815	COG1253	flavin adenine dinucleotide binding
FY138_RS20825	COG1692	metallophosphoesterase
FY138_RS20840	COG0217	transcriptional regulatory protein
FY138_RS20845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS20850	COG0840	transmembrane signaling receptor activity
FY138_RS20855	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY138_RS20860	COG0632	four-way junction helicase activity
FY138_RS20865	COG2255	four-way junction helicase activity
FY138_RS20880	COG0494	nUDIX hydrolase
FY138_RS20890	COG0824	Thioesterase
FY138_RS20910	COG0823	Involved in the tonB-independent uptake of proteins
FY138_RS20915	COG2885	chlorophyll binding
FY138_RS20925	COG0037	tRNA processing
FY138_RS20930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY138_RS20935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY138_RS20950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY138_RS20965	COG0482	sulfurtransferase activity
FY138_RS20995	COG2835	tetraacyldisaccharide 4'-kinase activity
FY138_RS21000	COG2373	Large extracellular alpha-helical protein
FY138_RS21005	COG4953	penicillin-binding protein 1C
FY138_RS21015	COG1473	amidohydrolase
FY138_RS21020	COG1686	Belongs to the peptidase S11 family
FY138_RS21025	COG0523	cobalamin synthesis protein
FY138_RS21030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY138_RS21030	COG0425	Belongs to the sulfur carrier protein TusA family
FY138_RS21035	COG3034	peptidoglycan biosynthetic process
FY138_RS21040	COG0825	malonyl-CoA metabolic process
FY138_RS21045	COG4974	Belongs to the 'phage' integrase family
FY138_RS21055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY138_RS21060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY138_RS21100	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY138_RS21105	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY138_RS21125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY138_RS21130	COG2226	methyltransferase
FY138_RS21135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY138_RS21140	COG0287	Prephenate dehydrogenase
FY138_RS21150	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY138_RS21170	COG2884	Cell division ATP-binding protein ftsE
FY138_RS21205	COG0165	Argininosuccinate lyase
FY138_RS21210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY138_RS21220	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY138_RS21230	COG2086	electron transfer activity
FY138_RS21240	COG2096	Adenosyltransferase
FY138_RS21250	COG0300	oxidoreductase activity
FY138_RS21260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY138_RS21270	COG1396	sequence-specific DNA binding
FY138_RS21270	COG3800	Transcriptional regulator
FY138_RS21275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY138_RS21280	COG0625	glutathione transferase activity
FY138_RS21295	COG4770	biotin carboxylase activity
FY138_RS21300	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY138_RS21300	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY138_RS21305	COG0346	lactoylglutathione lyase activity
FY138_RS21320	COG4213	ABC transporter substrate-binding protein
FY138_RS21325	COG4214	carbohydrate transport
FY138_RS21330	COG1129	ABC transporter
FY138_RS21335	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY138_RS21345	COG1396	sequence-specific DNA binding
FY138_RS21400	COG3833	ABC-type maltose transport systems, permease component
FY138_RS21405	COG3842	ATPase activity
FY138_RS21420	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY138_RS21420	COG2273	Hydrolase Family 16
FY138_RS21425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY138_RS21440	COG0438	transferase activity, transferring glycosyl groups
FY138_RS21445	COG0438	transferase activity, transferring glycosyl groups
FY138_RS21465	COG3206	protein involved in exopolysaccharide biosynthesis
FY138_RS21465	COG0489	protein tyrosine kinase activity
FY138_RS21475	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY138_RS21490	COG2244	polysaccharide biosynthetic process
FY138_RS21555	COG0697	spore germination
FY138_RS21560	COG0653	protein targeting
FY138_RS21565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY138_RS21570	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY138_RS21580	COG0494	nUDIX hydrolase
FY138_RS21595	COG2226	methyltransferase
FY138_RS21600	COG1040	competence protein
FY138_RS21610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY138_RS21620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY138_RS21635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY138_RS21640	COG4150	thiosulfate binding
FY138_RS21650	COG4208	sulfate ABC transporter
FY138_RS21655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY138_RS21660	COG4335	DNA alkylation repair
FY138_RS21675	COG5001	Diguanylate cyclase
FY138_RS21680	COG2264	protein methyltransferase activity
FY138_RS21695	COG3254	rhamnose metabolic process
FY138_RS21700	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS21705	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS21710	COG1129	ABC transporter
FY138_RS21720	COG1349	DNA-binding transcription factor activity
FY138_RS21725	COG3347	Dehydrogenase
FY138_RS21725	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS21730	COG4952	isomerase
FY138_RS21735	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY138_RS21740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY138_RS21760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY138_RS21765	COG1960	acyl-CoA dehydrogenase activity
FY138_RS21775	COG0183	Belongs to the thiolase family
FY138_RS21780	COG1960	acyl-CoA dehydrogenase activity
FY138_RS21790	COG0022	dehydrogenase e1 component
FY138_RS21800	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY138_RS21805	COG2391	methyltransferase activity
FY138_RS21815	COG0640	Transcriptional regulator
FY138_RS21820	COG3453	Protein conserved in bacteria
FY138_RS21820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY138_RS21830	COG0300	oxidoreductase activity
FY138_RS21845	COG2186	Transcriptional regulator
FY138_RS21855	COG0601	transmembrane transport
FY138_RS21865	COG0444	Belongs to the ABC transporter superfamily
FY138_RS21870	COG4608	Belongs to the ABC transporter superfamily
FY138_RS22005	COG2369	cell adhesion
FY138_RS22010	COG4383	Mu-like prophage protein gp29
FY138_RS22015	COG4373	Mu-like prophage FluMu protein gp28
FY138_RS22150	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS22155	COG1733	regulation of RNA biosynthetic process
FY138_RS22165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS22170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS22185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS22190	COG1473	amidohydrolase
FY138_RS22195	COG0747	negative chemotaxis
FY138_RS22210	COG4166	transmembrane transport
FY138_RS22215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS22220	COG0583	DNA-binding transcription factor activity
FY138_RS22230	COG0667	Aldo Keto reductase
FY138_RS22240	COG0444	Belongs to the ABC transporter superfamily
FY138_RS22255	COG0747	negative chemotaxis
FY138_RS22265	COG1960	acyl-CoA dehydrogenase activity
FY138_RS22295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS22300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY138_RS22310	COG1959	2 iron, 2 sulfur cluster binding
FY138_RS22315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS22320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS22325	COG1473	amidohydrolase
FY138_RS22340	COG1126	abc transporter atp-binding protein
FY138_RS22345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS22355	COG0583	DNA-binding transcription factor activity
FY138_RS22370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS22380	COG1522	sequence-specific DNA binding
FY138_RS22385	COG4172	Belongs to the ABC transporter superfamily
FY138_RS22390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS22425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS22430	COG1012	belongs to the aldehyde dehydrogenase family
FY138_RS22435	COG0473	3-isopropylmalate dehydrogenase activity
FY138_RS22440	COG1012	belongs to the aldehyde dehydrogenase family
FY138_RS22485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_RS22490	COG1120	ATPase activity
FY138_RS22500	COG2226	methyltransferase
FY138_RS22515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_RS22520	COG1120	ATPase activity
FY138_RS22525	COG1595	DNA-templated transcription, initiation
FY138_RS22545	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY138_RS22550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_RS22570	COG0673	inositol 2-dehydrogenase activity
FY138_RS22575	COG0673	inositol 2-dehydrogenase activity
FY138_RS22585	COG1175	transmembrane transport
FY138_RS22590	COG0395	ABC-type sugar transport system, permease component
FY138_RS22595	COG3842	ATPase activity
FY138_RS22605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_RS22610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY138_RS22615	COG2197	response regulator
FY138_RS22620	COG0601	transmembrane transport
FY138_RS22625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS22645	COG0747	negative chemotaxis
FY138_RS22660	COG1446	asparaginase
FY138_RS22665	COG0583	DNA-binding transcription factor activity
FY138_RS22670	COG0601	transmembrane transport
FY138_RS22675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS22690	COG0747	negative chemotaxis
FY138_RS22695	COG1473	amidohydrolase
FY138_RS22710	COG1129	ABC transporter
FY138_RS22715	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS22720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY138_RS22725	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY138_RS22735	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY138_RS22750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS22760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS22765	COG2079	MmgE PrpD family protein
FY138_RS22770	COG1126	abc transporter atp-binding protein
FY138_RS22775	COG0765	amino acid transport
FY138_RS22790	COG0281	malic enzyme
FY138_RS22790	COG0280	phosphate acetyltransferase
FY138_RS22795	COG0583	DNA-binding transcription factor activity
FY138_RS22820	COG1175	transmembrane transport
FY138_RS22825	COG0395	ABC-type sugar transport system, permease component
FY138_RS22840	COG0673	inositol 2-dehydrogenase activity
FY138_RS22850	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY138_RS22855	COG0720	synthase
FY138_RS22860	COG0602	queuosine metabolic process
FY138_RS22865	COG0673	inositol 2-dehydrogenase activity
FY138_RS22875	COG3842	ATPase activity
FY138_RS22890	COG1653	transport
FY138_RS22895	COG1609	Transcriptional regulator
FY138_RS22910	COG2094	Belongs to the DNA glycosylase MPG family
FY138_RS22920	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS22930	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_RS22935	COG0840	transmembrane signaling receptor activity
FY138_RS22940	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY138_RS22950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY138_RS22955	COG1596	polysaccharide export
FY138_RS22960	COG3307	-O-antigen
FY138_RS22990	COG2197	response regulator
FY138_RS23000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_RS23025	COG2942	2-epimerase
FY138_RS23035	COG1215	transferase activity, transferring glycosyl groups
FY138_RS23055	COG1473	amidohydrolase
FY138_RS23065	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS23070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY138_RS23075	COG1301	dicarboxylic acid transport
FY138_RS23080	COG4191	Histidine kinase
FY138_RS23085	COG2204	response regulator
FY138_RS23100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS23105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY138_RS23110	COG1522	sequence-specific DNA binding
FY138_RS23115	COG0351	phosphomethylpyrimidine kinase
FY138_RS23120	COG0352	thiamine-phosphate diphosphorylase activity
FY138_RS23125	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY138_RS23130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY138_RS23135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_RS23145	COG1501	Belongs to the glycosyl hydrolase 31 family
FY138_RS23150	COG0395	ABC-type sugar transport system, permease component
FY138_RS23155	COG1175	transmembrane transport
FY138_RS23160	COG1653	transport
FY138_RS23165	COG3842	ATPase activity
FY138_RS23170	COG2188	Transcriptional regulator
FY138_RS23180	COG4989	oxidoreductase activity
FY138_RS23215	COG0438	transferase activity, transferring glycosyl groups
FY138_RS23220	COG0747	negative chemotaxis
FY138_RS23225	COG0601	transmembrane transport
FY138_RS23235	COG3964	amidohydrolase
FY138_RS23250	COG1921	L-seryl-tRNASec selenium transferase activity
FY138_RS23255	COG4172	Belongs to the ABC transporter superfamily
FY138_RS23260	COG0625	glutathione transferase activity
FY138_RS23275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS23280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY138_RS23280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY138_RS23285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY138_RS23305	COG1312	Catalyzes the dehydration of D-mannonate
FY138_RS23310	COG1063	alcohol dehydrogenase
FY138_RS23315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY138_RS23325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY138_RS23330	COG2186	Transcriptional regulator
FY138_RS23335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY138_RS23340	COG0850	regulation of cytokinetic process
FY138_RS23345	COG2894	cell division
FY138_RS23350	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY138_RS23355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS23365	COG5001	Diguanylate cyclase
FY138_RS23380	COG0673	inositol 2-dehydrogenase activity
FY138_RS23390	COG1653	transport
FY138_RS23395	COG1175	transmembrane transport
FY138_RS23400	COG0395	ABC-type sugar transport system, permease component
FY138_RS23405	COG3842	ATPase activity
FY138_RS23415	COG0673	inositol 2-dehydrogenase activity
FY138_RS23445	COG0587	DNA-directed DNA polymerase activity
FY138_RS23450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY138_RS23465	COG2186	Transcriptional regulator
FY138_RS23470	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS23475	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS23480	COG1129	ABC transporter
FY138_RS23485	COG1879	ABC-type sugar transport system periplasmic component
FY138_RS23490	COG0129	dihydroxy-acid dehydratase activity
FY138_RS23500	COG0346	lactoylglutathione lyase activity
FY138_RS23515	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY138_RS23520	COG4608	Belongs to the ABC transporter superfamily
FY138_RS23530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS23535	COG0601	transmembrane transport
FY138_RS23540	COG0747	negative chemotaxis
FY138_RS23550	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY138_RS23555	COG5001	Diguanylate cyclase
FY138_RS23565	COG3257	ureidoglycine aminohydrolase activity
FY138_RS23575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_RS23580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY138_RS23590	COG1129	ABC transporter
FY138_RS23595	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS23600	COG1879	ABC-type sugar transport system periplasmic component
FY138_RS23605	COG0583	DNA-binding transcription factor activity
FY138_RS23630	COG3047	cAMP biosynthetic process
FY138_RS23640	COG3842	ATPase activity
FY138_RS23645	COG0395	ABC-type sugar transport system, permease component
FY138_RS23650	COG1175	transmembrane transport
FY138_RS23655	COG1653	transport
FY138_RS23660	COG0523	cobalamin synthesis protein
FY138_RS23675	COG0523	cobalamin synthesis protein
FY138_RS23680	COG1121	(ABC) transporter
FY138_RS23690	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY138_RS23695	COG0454	-acetyltransferase
FY138_RS23710	COG0626	cystathionine gamma-synthase activity
FY138_RS23715	COG2182	Extracellular solute-binding protein
FY138_RS23725	COG0395	ABC-type sugar transport system, permease component
FY138_RS23740	COG0395	ABC-type sugar transport system, permease component
FY138_RS23745	COG1175	transmembrane transport
FY138_RS23750	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY138_RS23755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_RS23765	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS23770	COG1063	alcohol dehydrogenase
FY138_RS23775	COG1609	Transcriptional regulator
FY138_RS23780	COG2223	nitrite transmembrane transporter activity
FY138_RS23785	COG4977	sequence-specific DNA binding
FY138_RS23815	COG0667	Aldo Keto reductase
FY138_RS23830	COG2186	Transcriptional regulator
FY138_RS23835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_RS23840	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY138_RS23845	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS23850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_RS23855	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_RS23860	COG3618	amidohydrolase
FY138_RS23870	COG1175	transmembrane transport
FY138_RS23875	COG0395	ABC-type sugar transport system, permease component
FY138_RS23880	COG3842	ATPase activity
FY138_RS23895	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY138_RS23900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY138_RS23925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY138_RS23935	COG1278	Cold shock
FY138_RS23945	COG0673	inositol 2-dehydrogenase activity
FY138_RS23960	COG0673	inositol 2-dehydrogenase activity
FY138_RS23965	COG1309	transcriptional regulator
FY138_RS23970	COG1653	transport
FY138_RS23975	COG1175	transmembrane transport
FY138_RS23980	COG0395	ABC-type sugar transport system, permease component
FY138_RS23985	COG3842	ATPase activity
FY138_RS23990	COG1082	Xylose isomerase domain protein TIM barrel
FY138_RS24005	COG1609	Transcriptional regulator
FY138_RS24035	COG1175	transmembrane transport
FY138_RS24040	COG0395	ABC-type sugar transport system, permease component
FY138_RS24045	COG1116	anion transmembrane transporter activity
FY138_RS24050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_RS24055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY138_RS24070	COG3842	ATPase activity
FY138_RS24075	COG0395	ABC-type sugar transport system, permease component
FY138_RS24085	COG1653	transport
FY138_RS24120	COG3842	ATPase activity
FY138_RS24130	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_RS24135	COG0395	ABC-type sugar transport system, permease component
FY138_RS24195	COG2233	PERMEase
FY138_RS24210	COG5002	protein histidine kinase activity
FY138_RS24215	COG0745	RESPONSE REGULATOR receiver
FY138_RS24220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_RS24225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY138_RS24230	COG0702	epimerase
FY138_RS24240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY138_RS24275	COG2235	arginine
FY138_RS24285	COG0628	permease
FY138_RS24305	COG1522	sequence-specific DNA binding
FY138_RS24325	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS24340	COG1414	Transcriptional regulator
FY138_RS24350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY138_RS24380	COG4566	intracellular signal transduction
FY138_RS24385	COG4566	intracellular signal transduction
FY138_RS24395	COG0243	molybdopterin cofactor binding
FY138_RS24400	COG0783	Belongs to the Dps family
FY138_RS24420	COG0596	Alpha beta hydrolase
FY138_RS24430	COG1764	response to oxidative stress
FY138_RS24445	COG0596	Alpha beta hydrolase
FY138_RS24480	COG4172	Belongs to the ABC transporter superfamily
FY138_RS24505	COG0601	transmembrane transport
FY138_RS24510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS24515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_RS24525	COG4106	trans-aconitate 2-methyltransferase activity
FY138_RS24530	COG0025	NhaP-type Na H and K H
FY138_RS24535	COG4302	ethanolamine ammonia-lyase activity
FY138_RS24560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY138_RS24565	COG1349	DNA-binding transcription factor activity
FY138_RS24570	COG4608	Belongs to the ABC transporter superfamily
FY138_RS24580	COG0601	transmembrane transport
FY138_RS24585	COG0747	negative chemotaxis
FY138_RS24590	COG1454	alcohol dehydrogenase
FY138_RS24595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY138_RS24600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY138_RS24605	COG0411	ABC transporter
FY138_RS24640	COG1192	Involved in chromosome partitioning
FY138_RS24645	COG1475	DNA binding
FY138_RS24650	COG0640	Transcriptional regulator
FY138_RS24665	COG1126	abc transporter atp-binding protein
FY138_RS24675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_RS24680	COG1609	Transcriptional regulator
FY138_RS24715	COG3239	Fatty acid desaturase
FY138_RS24725	COG1278	Cold shock
FY138_RS24805	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY138_RS24805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY138_RS24845	COG4191	Histidine kinase
FY138_RS24860	COG0640	Transcriptional regulator
FY138_RS24890	COG4977	sequence-specific DNA binding
FY138_RS24895	COG2211	Major facilitator Superfamily
FY138_RS24900	COG2807	transmembrane transport
FY138_RS24905	COG1846	Transcriptional regulator
FY138_RS24920	COG2814	Major facilitator Superfamily
FY138_RS24950	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY138_RS24965	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY138_RS24970	COG0583	DNA-binding transcription factor activity
FY138_RS24985	COG0071	Belongs to the small heat shock protein (HSP20) family
FY138_RS25035	COG3838	Conjugal transfer protein Trbc
FY138_RS25040	COG3702	type iv secretory pathway
FY138_RS25045	COG3451	type IV secretory pathway VirB4
FY138_RS25060	COG3704	protein secretion by the type IV secretion system
FY138_RS25070	COG3736	Type IV secretory pathway, component VirB8
FY138_RS25075	COG3504	Conjugal transfer protein
FY138_RS25080	COG2948	multi-organism process
FY138_RS25085	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY138_RS25190	COG3831	ATPase activity
FY138_RS25205	COG3505	Type IV secretory pathway VirD4
FY138_RS25225	COG0583	DNA-binding transcription factor activity
FY138_RS25270	COG0745	RESPONSE REGULATOR receiver
FY138_RS25310	COG3842	ATPase activity
FY138_RS25315	COG4208	sulfate ABC transporter
FY138_RS25320	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_RS25340	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY138_RS25345	COG1942	4-Oxalocrotonate Tautomerase
FY138_RS25355	COG3971	2-oxopent-4-enoate hydratase activity
FY138_RS25365	COG1414	Transcriptional regulator
FY138_RS25375	COG1137	ATPase activity
FY138_RS25390	COG4177	L-phenylalanine transmembrane transporter activity
FY138_RS25410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY138_RS25415	COG1175	transmembrane transport
FY138_RS25420	COG0395	ABC-type sugar transport system, permease component
FY138_RS25430	COG0366	Alpha amylase catalytic
FY138_RS25435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY138_RS25440	COG1082	Xylose isomerase domain protein TIM barrel
FY138_RS25445	COG3842	ATPase activity
FY138_RS25455	COG1940	carbohydrate kinase activity
FY138_RS25460	COG0395	ABC-type sugar transport system, permease component
FY138_RS25470	COG2182	Extracellular solute-binding protein
FY138_RS25475	COG0673	inositol 2-dehydrogenase activity
FY138_RS25505	COG1126	abc transporter atp-binding protein
FY138_RS25510	COG0765	amino acid transport
FY138_RS25515	COG0765	amino acid transport
FY138_RS25525	COG4608	Belongs to the ABC transporter superfamily
FY138_RS25535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS25550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY138_RS25555	COG0583	DNA-binding transcription factor activity
FY138_RS25560	COG2423	ornithine cyclodeaminase activity
FY138_RS25570	COG1957	nucleoside hydrolase
FY138_RS25580	COG1309	transcriptional regulator
FY138_RS25590	COG1335	isochorismatase
FY138_RS25595	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS25600	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS25645	COG0583	DNA-binding transcription factor activity
FY138_RS25650	COG1902	pentaerythritol trinitrate reductase activity
FY138_RS25655	COG0583	DNA-binding transcription factor activity
FY138_RS25660	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS25670	COG1335	isochorismatase
FY138_RS25675	COG0583	DNA-binding transcription factor activity
FY138_RS25685	COG1695	Transcriptional regulator
FY138_RS25770	COG2207	Transcriptional regulator
FY138_RS25830	COG1802	Transcriptional regulator
FY138_RS25835	COG3485	protocatechuate 3,4-dioxygenase
FY138_RS25840	COG3971	2-oxopent-4-enoate hydratase activity
FY138_RS25855	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY138_RS25860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY138_RS25875	COG1063	alcohol dehydrogenase
FY138_RS25885	COG1960	acyl-CoA dehydrogenase activity
FY138_RS25890	COG1024	Enoyl-CoA hydratase
FY138_RS25900	COG1012	belongs to the aldehyde dehydrogenase family
FY138_RS25905	COG0477	Major facilitator Superfamily
FY138_RS25920	COG3706	GGDEF domain
FY138_RS25940	COG1846	Transcriptional regulator
FY138_RS25980	COG1012	belongs to the aldehyde dehydrogenase family
FY138_RS25990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY138_RS26000	COG3386	PFAM SMP-30 Gluconolaconase
FY138_RS26005	COG3622	Belongs to the hyi family
FY138_RS26010	COG2084	Dehydrogenase
FY138_RS26035	COG1940	carbohydrate kinase activity
FY138_RS26040	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_RS26050	COG1129	ABC transporter
FY138_RS26070	COG0583	DNA-binding transcription factor activity
FY138_RS26075	COG2271	Major facilitator Superfamily
FY138_RS26085	COG2272	Belongs to the type-B carboxylesterase lipase family
FY138_RS26105	COG1129	ABC transporter
FY138_RS26130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY138_RS26140	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY138_RS26175	COG0583	DNA-binding transcription factor activity
FY138_RS26180	COG1414	Transcriptional regulator
FY138_RS26190	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_RS26200	COG3842	ATPase activity
FY138_RS26205	COG1175	transmembrane transport
FY138_RS26210	COG0395	ABC-type sugar transport system, permease component
FY138_RS26220	COG0477	Major facilitator Superfamily
FY138_RS26255	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY138_RS26270	COG0583	DNA-binding transcription factor activity
FY138_RS26275	COG0747	negative chemotaxis
FY138_RS26285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS26300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_RS26310	COG4215	(ABC) transporter
FY138_RS26365	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY138_RS26370	COG0251	oxidation-reduction process
FY138_RS26405	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS26410	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_RS26415	COG1335	isochorismatase
FY138_RS26425	COG1309	transcriptional regulator
FY138_RS26430	COG4604	ABC transporter, ATP-binding protein
FY138_RS26435	COG4605	iron ion homeostasis
FY138_RS26440	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_RS26450	COG2132	Multicopper oxidase
FY138_RS26455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY138_RS26505	COG1695	Transcriptional regulator
FY138_RS26540	COG2132	Multicopper oxidase
FY138_RS26575	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY138_RS26595	COG1192	Involved in chromosome partitioning
FY138_RS26600	COG1475	DNA binding
FY138_RS26605	COG0640	Transcriptional regulator
FY138_RS26610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY138_RS26640	COG2211	Major facilitator Superfamily
FY138_RS26685	COG4974	Belongs to the 'phage' integrase family
FY138_RS26690	COG1051	belongs to the nudix hydrolase family
FY138_RS26735	COG1475	DNA binding
FY138_RS26760	COG2824	Alkylphosphonate utilization operon protein PhnA
FY138_RS26780	COG1280	lysine exporter protein (LysE YggA)
FY138_RS26845	COG5489	Protein of unknown function (DUF736)
FY138_RS26935	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY138_RS26950	COG0747	negative chemotaxis
FY138_RS26970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS26975	COG0584	glycerophosphoryl diester phosphodiesterase
FY138_RS26980	COG0483	inositol monophosphate 1-phosphatase activity
FY138_RS27045	COG3161	chorismate lyase activity
FY138_RS27285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_RS27315	COG0583	DNA-binding transcription factor activity
FY138_RS27320	COG0747	negative chemotaxis
FY138_RS27335	COG0252	asparaginase activity
FY138_RS27340	COG0583	DNA-binding transcription factor activity
FY138_RS27360	COG3842	ATPase activity
FY138_RS27385	COG3701	Conjugal transfer protein
FY138_RS27390	COG3846	protein secretion by the type IV secretion system
FY138_RS27400	COG5314	conjugation
FY138_RS27405	COG3451	type IV secretory pathway VirB4
FY138_RS27420	COG4962	Type ii secretion system protein e