locus-tag	class	description
FY142_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY142_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY142_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY142_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY142_RS00025	COG1420	regulation of RNA biosynthetic process
FY142_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY142_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY142_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY142_RS00050	COG1137	ATPase activity
FY142_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY142_RS00065	COG0616	signal peptide processing
FY142_RS00070	COG0776	regulation of translation
FY142_RS00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY142_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY142_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY142_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY142_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY142_RS00115	COG0728	peptidoglycan biosynthetic process
FY142_RS00125	COG0180	Tryptophanyl-tRNA synthetase
FY142_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY142_RS00140	COG1214	PFAM Peptidase M22, glycoprotease
FY142_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY142_RS00165	COG1702	phosphate starvation-inducible protein PhoH
FY142_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY142_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY142_RS00185	COG1396	sequence-specific DNA binding
FY142_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY142_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY142_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_RS00210	COG0242	peptide deformylase activity
FY142_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY142_RS00220	COG0101	tRNA pseudouridine synthase activity
FY142_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY142_RS00235	COG2171	N-acyltransferase activity
FY142_RS00245	COG0840	transmembrane signaling receptor activity
FY142_RS00250	COG1957	nucleoside hydrolase
FY142_RS00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY142_RS00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY142_RS00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY142_RS00295	COG0706	membrane insertase activity
FY142_RS00300	COG0594	ribonuclease P activity
FY142_RS00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY142_RS00310	COG0840	transmembrane signaling receptor activity
FY142_RS00325	COG2226	methyltransferase
FY142_RS00330	COG3842	ATPase activity
FY142_RS00335	COG1175	transmembrane transport
FY142_RS00340	COG0395	ABC-type sugar transport system, permease component
FY142_RS00355	COG0427	acetyl-CoA hydrolase
FY142_RS00365	COG3938	Belongs to the proline racemase family
FY142_RS00370	COG0418	dihydroorotase activity
FY142_RS00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY142_RS00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY142_RS00400	COG0166	Belongs to the GPI family
FY142_RS00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY142_RS00410	COG3842	ATPase activity
FY142_RS00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY142_RS00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY142_RS00425	COG4774	siderophore transport
FY142_RS00470	COG2326	polyphosphate kinase activity
FY142_RS00475	COG5002	protein histidine kinase activity
FY142_RS00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY142_RS00485	COG0573	inorganic phosphate transmembrane transporter activity
FY142_RS00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY142_RS00500	COG0704	Plays a role in the regulation of phosphate uptake
FY142_RS00505	COG0745	RESPONSE REGULATOR receiver
FY142_RS00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY142_RS00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY142_RS00530	COG2967	ApaG domain
FY142_RS00540	COG0717	Belongs to the dCTP deaminase family
FY142_RS00550	COG0582	viral genome integration into host DNA
FY142_RS00575	COG0419	ATPase involved in DNA repair
FY142_RS00595	COG1396	sequence-specific DNA binding
FY142_RS00635	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY142_RS00640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY142_RS00690	COG0167	dihydroorotate dehydrogenase activity
FY142_RS00725	COG1959	2 iron, 2 sulfur cluster binding
FY142_RS00730	COG1201	RNA secondary structure unwinding
FY142_RS00760	COG1960	acyl-CoA dehydrogenase activity
FY142_RS00765	COG0183	Belongs to the thiolase family
FY142_RS00770	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY142_RS00770	COG1024	Enoyl-CoA hydratase
FY142_RS00795	COG1320	monovalent cation:proton antiporter activity
FY142_RS00800	COG2212	antiporter activity
FY142_RS00805	COG1863	multisubunit Na H antiporter MnhE subunit
FY142_RS00810	COG0651	ATP synthesis coupled electron transport
FY142_RS00815	COG1006	Multisubunit Na H antiporter MnhC subunit
FY142_RS00820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY142_RS00820	COG2111	Na H antiporter
FY142_RS00830	COG0840	transmembrane signaling receptor activity
FY142_RS00840	COG0745	RESPONSE REGULATOR receiver
FY142_RS00845	COG2198	Histidine kinase
FY142_RS00845	COG0643	Histidine kinase
FY142_RS00850	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY142_RS00855	COG2201	protein-glutamate methylesterase activity
FY142_RS00860	COG0745	RESPONSE REGULATOR receiver
FY142_RS00865	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY142_RS00875	COG1766	The M ring may be actively involved in energy transduction
FY142_RS00880	COG2771	luxR family
FY142_RS00890	COG0840	transmembrane signaling receptor activity
FY142_RS00890	COG2972	Histidine kinase
FY142_RS00895	COG0784	Response regulator, receiver
FY142_RS00895	COG2198	Histidine kinase
FY142_RS00895	COG2205	protein histidine kinase activity
FY142_RS00900	COG1970	mechanosensitive ion channel activity
FY142_RS00905	COG0436	Aminotransferase
FY142_RS00920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY142_RS00925	COG0424	maF-like protein
FY142_RS00930	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY142_RS00940	COG5328	Belongs to the UPF0262 family
FY142_RS00945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY142_RS00955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY142_RS00975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY142_RS00985	COG1338	Plays a role in the flagellum-specific transport system
FY142_RS00995	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY142_RS01005	COG1706	bacterial-type flagellum-dependent cell motility
FY142_RS01010	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY142_RS01015	COG4786	Flagellar basal body rod
FY142_RS01020	COG1677	Flagellar hook-basal body complex protein FliE
FY142_RS01025	COG1558	bacterial-type flagellum-dependent cell motility
FY142_RS01030	COG1815	bacterial-type flagellum-dependent cell motility
FY142_RS01040	COG1157	protein secretion by the type III secretion system
FY142_RS01045	COG4786	Flagellar basal body rod
FY142_RS01055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY142_RS01060	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY142_RS01065	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY142_RS01070	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY142_RS01075	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY142_RS01095	COG1360	Flagellar Motor Protein
FY142_RS01140	COG5443	negative regulation of bacterial-type flagellum assembly
FY142_RS01145	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY142_RS01155	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY142_RS01195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY142_RS01200	COG1609	Transcriptional regulator
FY142_RS01205	COG1653	transport
FY142_RS01210	COG1175	transmembrane transport
FY142_RS01215	COG0395	ABC-type sugar transport system, permease component
FY142_RS01220	COG0366	Alpha amylase catalytic
FY142_RS01225	COG3842	ATPase activity
FY142_RS01240	COG0129	dihydroxy-acid dehydratase activity
FY142_RS01245	COG0363	glucosamine-6-phosphate deaminase activity
FY142_RS01250	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY142_RS01255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS01265	COG2081	HI0933 family
FY142_RS01285	COG2224	Isocitrate lyase
FY142_RS01300	COG3842	ATPase activity
FY142_RS01305	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_RS01310	COG1177	transmembrane transport
FY142_RS01325	COG2205	protein histidine kinase activity
FY142_RS01335	COG0248	Ppx GppA phosphatase
FY142_RS01340	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY142_RS01345	COG0477	Major facilitator Superfamily
FY142_RS01375	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY142_RS01380	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY142_RS01390	COG0142	geranyltranstransferase activity
FY142_RS01415	COG0752	glycyl-tRNA synthetase alpha subunit
FY142_RS01425	COG1704	LemA family
FY142_RS01430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY142_RS01440	COG0751	glycine-tRNA ligase activity
FY142_RS01445	COG1683	Conserved Protein
FY142_RS01450	COG0840	transmembrane signaling receptor activity
FY142_RS01460	COG0151	Belongs to the GarS family
FY142_RS01465	COG2183	response to ionizing radiation
FY142_RS01470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY142_RS01495	COG0583	DNA-binding transcription factor activity
FY142_RS01515	COG0306	phosphate transporter
FY142_RS01525	COG0561	phosphatase activity
FY142_RS01530	COG0438	transferase activity, transferring glycosyl groups
FY142_RS01535	COG2186	Transcriptional regulator
FY142_RS01550	COG0583	DNA-binding transcription factor activity
FY142_RS01555	COG0277	FAD linked oxidase domain protein
FY142_RS01560	COG0277	FAD linked oxidase domain protein
FY142_RS01565	COG0247	lactate metabolic process
FY142_RS01575	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_RS01580	COG2818	Glycosylase
FY142_RS01590	COG2855	membrane
FY142_RS01595	COG0583	DNA-binding transcription factor activity
FY142_RS01625	COG0124	histidyl-tRNA synthetase
FY142_RS01635	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY142_RS01640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY142_RS01645	COG2259	Doxx family
FY142_RS01655	COG0459	protein refolding
FY142_RS01660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY142_RS01670	COG0196	riboflavin kinase activity
FY142_RS01675	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY142_RS01685	COG0590	tRNA wobble adenosine to inosine editing
FY142_RS01690	COG1187	pseudouridine synthase activity
FY142_RS01695	COG0742	ribosomal rna small subunit methyltransferase
FY142_RS01700	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY142_RS01710	COG0312	modulator of DNA gyrase
FY142_RS01715	COG0483	inositol monophosphate 1-phosphatase activity
FY142_RS01725	COG1519	Transferase
FY142_RS01735	COG1663	tetraacyldisaccharide 4'-kinase activity
FY142_RS01745	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY142_RS01750	COG0745	RESPONSE REGULATOR receiver
FY142_RS01755	COG5001	Diguanylate cyclase
FY142_RS01755	COG3300	MHYT domain
FY142_RS01760	COG3386	PFAM SMP-30 Gluconolaconase
FY142_RS01765	COG0800	Aldolase
FY142_RS01770	COG3734	2-keto-3-deoxy-galactonokinase
FY142_RS01775	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS01780	COG1414	Transcriptional regulator
FY142_RS01785	COG2197	response regulator
FY142_RS01800	COG0598	Magnesium transport protein CorA
FY142_RS01805	COG3158	transport of potassium into the cell
FY142_RS01820	COG0356	it plays a direct role in the translocation of protons across the membrane
FY142_RS01830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY142_RS01835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY142_RS01850	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY142_RS01870	COG0009	L-threonylcarbamoyladenylate synthase
FY142_RS01880	COG4638	Rieske (2fe-2S)
FY142_RS01905	COG1960	acyl-CoA dehydrogenase activity
FY142_RS01920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY142_RS01925	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY142_RS01930	COG0840	transmembrane signaling receptor activity
FY142_RS01940	COG1522	sequence-specific DNA binding
FY142_RS01965	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY142_RS01970	COG1741	Belongs to the pirin family
FY142_RS01975	COG1722	exodeoxyribonuclease VII activity
FY142_RS01980	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY142_RS01985	COG1268	BioY protein
FY142_RS01990	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY142_RS01995	COG1122	ATPase activity
FY142_RS02000	COG3214	Protein conserved in bacteria
FY142_RS02005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY142_RS02005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY142_RS02010	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY142_RS02030	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY142_RS02045	COG0259	pyridoxamine-phosphate oxidase activity
FY142_RS02075	COG0312	modulator of DNA gyrase
FY142_RS02090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY142_RS02095	COG0109	protoheme IX farnesyltransferase activity
FY142_RS02105	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY142_RS02120	COG3346	SURF1 family
FY142_RS02125	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY142_RS02130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY142_RS02135	COG0328	RNA-DNA hybrid ribonuclease activity
FY142_RS02145	COG0678	peroxiredoxin activity
FY142_RS02145	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY142_RS02155	COG1678	Uncharacterized ACR, COG1678
FY142_RS02160	COG3237	CsbD-like
FY142_RS02170	COG5001	Diguanylate cyclase
FY142_RS02170	COG3300	MHYT domain
FY142_RS02175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY142_RS02180	COG0612	Peptidase, M16
FY142_RS02205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY142_RS02210	COG1802	Transcriptional regulator
FY142_RS02225	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY142_RS02230	COG3609	addiction module antidote protein, CC2985 family
FY142_RS02235	COG3668	Plasmid stabilization system
FY142_RS02245	COG1194	a g-specific adenine glycosylase
FY142_RS02260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY142_RS02265	COG1196	nuclear chromosome segregation
FY142_RS02270	COG2514	catechol 2,3-dioxygenase activity
FY142_RS02275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY142_RS02275	COG0574	Belongs to the PEP-utilizing enzyme family
FY142_RS02285	COG1823	symporter activity
FY142_RS02310	COG0579	oxidoreductase
FY142_RS02325	COG2895	sulfate adenylyltransferase (ATP) activity
FY142_RS02330	COG0175	sulfate reduction
FY142_RS02335	COG0175	sulfate reduction
FY142_RS02340	COG1959	2 iron, 2 sulfur cluster binding
FY142_RS02345	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY142_RS02350	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY142_RS02355	COG4208	sulfate ABC transporter
FY142_RS02360	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY142_RS02370	COG2199	diguanylate cyclase activity
FY142_RS02370	COG2200	EAL domain
FY142_RS02370	COG2203	Gaf domain
FY142_RS02380	COG1309	transcriptional regulator
FY142_RS02385	COG1012	belongs to the aldehyde dehydrogenase family
FY142_RS02390	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY142_RS02420	COG0625	glutathione transferase activity
FY142_RS02430	COG0477	Major facilitator Superfamily
FY142_RS02440	COG3657	addiction module killer protein
FY142_RS02450	COG1793	dna ligase
FY142_RS02470	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_RS02475	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_RS02480	COG1846	Transcriptional regulator
FY142_RS02485	COG1764	response to oxidative stress
FY142_RS02500	COG0488	(ABC) transporter
FY142_RS02535	COG4221	oxidoreductase activity
FY142_RS02550	COG0433	COG0433 Predicted ATPase
FY142_RS02560	COG1733	regulation of RNA biosynthetic process
FY142_RS02565	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY142_RS02580	COG0656	L-ascorbic acid biosynthetic process
FY142_RS02585	COG3781	membrane
FY142_RS02590	COG2378	regulation of single-species biofilm formation
FY142_RS02600	COG4106	trans-aconitate 2-methyltransferase activity
FY142_RS02605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY142_RS02610	COG0840	transmembrane signaling receptor activity
FY142_RS02615	COG0583	DNA-binding transcription factor activity
FY142_RS02630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY142_RS02650	COG3909	cytochrome
FY142_RS02655	COG2010	Cytochrome c
FY142_RS02690	COG0789	Transcriptional regulator
FY142_RS02715	COG0517	IMP dehydrogenase activity
FY142_RS02715	COG4175	Glycine betaine
FY142_RS02720	COG4176	ABC-type proline glycine betaine transport system permease component
FY142_RS02745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_RS02755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY142_RS02755	COG2169	Transcriptional regulator
FY142_RS02765	COG2514	catechol 2,3-dioxygenase activity
FY142_RS02780	COG1272	protein, Hemolysin III
FY142_RS02790	COG1280	lysine exporter protein (LysE YggA)
FY142_RS02795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY142_RS02800	COG2111	Na H antiporter
FY142_RS02800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY142_RS02805	COG2111	Na H antiporter
FY142_RS02810	COG1006	Multisubunit Na H antiporter MnhC subunit
FY142_RS02815	COG0651	ATP synthesis coupled electron transport
FY142_RS02820	COG1863	multisubunit Na H antiporter MnhE subunit
FY142_RS02825	COG2212	antiporter activity
FY142_RS02830	COG1320	monovalent cation:proton antiporter activity
FY142_RS02835	COG4957	zinc ion binding
FY142_RS02850	COG2166	iron-sulfur cluster assembly
FY142_RS02860	COG2205	protein histidine kinase activity
FY142_RS02905	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY142_RS02910	COG2983	Belongs to the UPF0260 family
FY142_RS02925	COG2217	Heavy metal translocating P-type atpase
FY142_RS02955	COG2814	Major facilitator Superfamily
FY142_RS02965	COG1621	beta-fructofuranosidase activity
FY142_RS02970	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY142_RS03020	COG4695	Portal protein
FY142_RS03125	COG4235	cytochrome complex assembly
FY142_RS03130	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY142_RS03135	COG1138	Cytochrome C-type biogenesis protein
FY142_RS03140	COG3088	subunit of a heme lyase
FY142_RS03145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY142_RS03150	COG0745	RESPONSE REGULATOR receiver
FY142_RS03155	COG2205	protein histidine kinase activity
FY142_RS03160	COG3011	Protein conserved in bacteria
FY142_RS03165	COG3713	MltA-interacting MipA family protein
FY142_RS03170	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY142_RS03175	COG2202	Pas domain
FY142_RS03175	COG2205	protein histidine kinase activity
FY142_RS03185	COG0308	aminopeptidase N
FY142_RS03190	COG0697	spore germination
FY142_RS03205	COG0443	Heat shock 70 kDa protein
FY142_RS03240	COG0604	alcohol dehydrogenase
FY142_RS03245	COG1733	regulation of RNA biosynthetic process
FY142_RS03250	COG1968	undecaprenyl-diphosphatase activity
FY142_RS03255	COG2239	Acts as a magnesium transporter
FY142_RS03260	COG2814	Major facilitator Superfamily
FY142_RS03285	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY142_RS03315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY142_RS03360	COG0741	lytic transglycosylase activity
FY142_RS03365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_RS03370	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY142_RS03375	COG0840	transmembrane signaling receptor activity
FY142_RS03385	COG1758	RNA polymerase activity
FY142_RS03405	COG0736	holo-[acyl-carrier-protein] synthase activity
FY142_RS03410	COG0681	Belongs to the peptidase S26 family
FY142_RS03415	COG0571	ribonuclease III activity
FY142_RS03420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY142_RS03430	COG0784	Response regulator, receiver
FY142_RS03435	COG1381	Involved in DNA repair and RecF pathway recombination
FY142_RS03445	COG2226	methyltransferase
FY142_RS03455	COG1418	mRNA catabolic process
FY142_RS03465	COG0346	lactoylglutathione lyase activity
FY142_RS03480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_RS03485	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY142_RS03490	COG0668	transmembrane transport
FY142_RS03500	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY142_RS03530	COG1742	UPF0060 membrane protein
FY142_RS03550	COG1183	phosphatidylcholine synthase activity
FY142_RS03555	COG0688	phosphatidylethanolamine metabolic process
FY142_RS03560	COG5265	(ABC) transporter
FY142_RS03600	COG2852	Protein conserved in bacteria
FY142_RS03605	COG0215	cysteine-tRNA ligase activity
FY142_RS03610	COG4221	oxidoreductase activity
FY142_RS03615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY142_RS03620	COG1286	toxin biosynthetic process
FY142_RS03635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY142_RS03645	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY142_RS03655	COG0305	Participates in initiation and elongation during chromosome replication
FY142_RS03675	COG0359	binds to the 23S rRNA
FY142_RS03685	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY142_RS03690	COG0360	Binds together with S18 to 16S ribosomal RNA
FY142_RS03700	COG0667	Aldo Keto reductase
FY142_RS03705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY142_RS03715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY142_RS03720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY142_RS03730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY142_RS03735	COG1561	YicC-like family, N-terminal region
FY142_RS03740	COG0194	GDP metabolic process
FY142_RS03755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY142_RS03760	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY142_RS03770	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY142_RS03785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY142_RS03805	COG3706	GGDEF domain
FY142_RS03805	COG4251	negative regulation of phosphorylation
FY142_RS03805	COG5001	Diguanylate cyclase
FY142_RS03805	COG2203	Gaf domain
FY142_RS03810	COG3300	MHYT domain
FY142_RS03810	COG5001	Diguanylate cyclase
FY142_RS03815	COG4191	Histidine kinase
FY142_RS03820	COG4566	intracellular signal transduction
FY142_RS03830	COG0488	(ABC) transporter
FY142_RS03835	COG3706	GGDEF domain
FY142_RS03845	COG0105	UTP biosynthetic process
FY142_RS03865	COG0314	molybdopterin synthase activity
FY142_RS03875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY142_RS03880	COG0322	excinuclease ABC activity
FY142_RS03885	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS03910	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY142_RS03915	COG0243	molybdopterin cofactor binding
FY142_RS03930	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY142_RS03935	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY142_RS03940	COG2226	methyltransferase
FY142_RS03945	COG0628	permease
FY142_RS03955	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY142_RS03960	COG0248	Ppx GppA phosphatase
FY142_RS03985	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY142_RS03995	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY142_RS04000	COG0477	Major facilitator Superfamily
FY142_RS04005	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY142_RS04015	COG0840	transmembrane signaling receptor activity
FY142_RS04020	COG0659	secondary active sulfate transmembrane transporter activity
FY142_RS04030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY142_RS04035	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY142_RS04045	COG0113	porphobilinogen synthase activity
FY142_RS04065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY142_RS04070	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY142_RS04075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY142_RS04075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY142_RS04085	COG1280	lysine exporter protein (LysE YggA)
FY142_RS04090	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY142_RS04095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY142_RS04100	COG2814	Major facilitator Superfamily
FY142_RS04105	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY142_RS04125	COG0416	fatty acid biosynthetic process
FY142_RS04130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY142_RS04135	COG0776	regulation of translation
FY142_RS04170	COG0601	transmembrane transport
FY142_RS04175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS04180	COG0444	Belongs to the ABC transporter superfamily
FY142_RS04190	COG0747	negative chemotaxis
FY142_RS04200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY142_RS04205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY142_RS04220	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY142_RS04225	COG0583	DNA-binding transcription factor activity
FY142_RS04230	COG0737	Belongs to the 5'-nucleotidase family
FY142_RS04250	COG2897	thiosulfate sulfurtransferase activity
FY142_RS04265	COG0415	Belongs to the DNA photolyase family
FY142_RS04275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY142_RS04305	COG3932	Exopolysaccharide synthesis, ExoD
FY142_RS04310	COG1238	metal cluster binding
FY142_RS04385	COG1612	heme a metabolic process
FY142_RS04395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY142_RS04400	COG0010	Belongs to the arginase family
FY142_RS04405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY142_RS04410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY142_RS04420	COG1832	CoA-binding protein
FY142_RS04445	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS04450	COG2124	cytochrome p450
FY142_RS04455	COG2199	diguanylate cyclase activity
FY142_RS04460	COG0740	serine-type endopeptidase activity
FY142_RS04465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY142_RS04470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY142_RS04480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY142_RS04510	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY142_RS04515	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY142_RS04520	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY142_RS04530	COG0649	NAD binding
FY142_RS04540	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY142_RS04545	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY142_RS04555	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY142_RS04560	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY142_RS04570	COG0713	ATP synthesis coupled electron transport
FY142_RS04585	COG1007	ATP synthesis coupled electron transport
FY142_RS04590	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY142_RS04590	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY142_RS04605	COG0442	prolyl-tRNA aminoacylation
FY142_RS04615	COG1136	(ABC) transporter
FY142_RS04630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY142_RS04650	COG0784	Response regulator, receiver
FY142_RS04660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY142_RS04665	COG0477	Major facilitator Superfamily
FY142_RS04680	COG0557	exoribonuclease II activity
FY142_RS04685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY142_RS04695	COG0758	DNA mediated transformation
FY142_RS04700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY142_RS04710	COG0540	Belongs to the ATCase OTCase family
FY142_RS04725	COG1960	acyl-CoA dehydrogenase activity
FY142_RS04730	COG0456	acetyltransferase
FY142_RS04750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY142_RS04755	COG2824	Alkylphosphonate utilization operon protein PhnA
FY142_RS04760	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY142_RS04765	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY142_RS04770	COG0154	amidase activity
FY142_RS04775	COG0456	acetyltransferase
FY142_RS04780	COG3811	Belongs to the UPF0386 family
FY142_RS04795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY142_RS04825	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY142_RS04830	COG0439	Biotin carboxylase
FY142_RS04835	COG0511	ligase activity, forming carbon-carbon bonds
FY142_RS04840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY142_RS04850	COG0436	Aminotransferase
FY142_RS04870	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS04875	COG1530	ribonuclease E activity
FY142_RS04885	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY142_RS04905	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY142_RS04910	COG0384	phenazine biosynthesis protein PhzF
FY142_RS04930	COG0633	Ferredoxin
FY142_RS04940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FY142_RS04945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY142_RS04950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY142_RS04960	COG3768	UPF0283 membrane protein
FY142_RS04965	COG3106	COG3106 Predicted ATPase
FY142_RS04995	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY142_RS05030	COG0537	adenosine 5'-monophosphoramidase activity
FY142_RS05060	COG0052	Belongs to the universal ribosomal protein uS2 family
FY142_RS05065	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY142_RS05070	COG0528	UMP kinase activity
FY142_RS05075	COG0233	cytoplasmic translational termination
FY142_RS05080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY142_RS05090	COG0750	zinc metalloprotease
FY142_RS05095	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY142_RS05100	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY142_RS05105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY142_RS05110	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY142_RS05115	COG3494	Protein of unknown function (DUF1009)
FY142_RS05120	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY142_RS05125	COG2186	Transcriptional regulator
FY142_RS05135	COG0765	amino acid transport
FY142_RS05140	COG0765	amino acid transport
FY142_RS05150	COG0372	Belongs to the citrate synthase family
FY142_RS05165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY142_RS05190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY142_RS05195	COG1459	type II secretion system
FY142_RS05250	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY142_RS05255	COG0148	phosphopyruvate hydratase activity
FY142_RS05265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY142_RS05270	COG0022	dehydrogenase e1 component
FY142_RS05270	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY142_RS05275	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY142_RS05285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY142_RS05295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY142_RS05300	COG0697	spore germination
FY142_RS05320	COG2867	negative regulation of translational initiation
FY142_RS05325	COG1546	Belongs to the CinA family
FY142_RS05330	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY142_RS05330	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY142_RS05340	COG3852	Histidine kinase
FY142_RS05345	COG2204	response regulator
FY142_RS05350	COG5000	phosphorelay sensor kinase activity
FY142_RS05355	COG2204	response regulator
FY142_RS05365	COG1923	regulation of RNA biosynthetic process
FY142_RS05370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY142_RS05375	COG3956	TIGRFAM MazG family protein
FY142_RS05385	COG1648	precorrin-2 dehydrogenase activity
FY142_RS05385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY142_RS05425	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY142_RS05425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY142_RS05430	COG0509	glycine decarboxylation via glycine cleavage system
FY142_RS05435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY142_RS05460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY142_RS05465	COG0564	pseudouridine synthase activity
FY142_RS05485	COG0251	oxidation-reduction process
FY142_RS05490	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY142_RS05500	COG1671	Belongs to the UPF0178 family
FY142_RS05515	COG0450	alkyl hydroperoxide reductase
FY142_RS05520	COG0625	glutathione transferase activity
FY142_RS05540	COG0431	NADPH-dependent FMN reductase
FY142_RS05550	COG0798	PFAM Bile acid sodium symporter
FY142_RS05555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY142_RS05570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY142_RS05570	COG0321	lipoyl(octanoyl) transferase activity
FY142_RS05575	COG0084	hydrolase, TatD family'
FY142_RS05580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY142_RS05590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY142_RS05645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY142_RS05650	COG2095	MarC family integral membrane protein
FY142_RS05655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY142_RS05655	COG0517	IMP dehydrogenase activity
FY142_RS05655	COG0617	tRNA 3'-terminal CCA addition
FY142_RS05665	COG0629	single-stranded DNA binding
FY142_RS05670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY142_RS05680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY142_RS05700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY142_RS05705	COG1121	(ABC) transporter
FY142_RS05725	COG0667	Aldo Keto reductase
FY142_RS05735	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY142_RS05815	COG2239	Acts as a magnesium transporter
FY142_RS05820	COG0243	molybdopterin cofactor binding
FY142_RS05830	COG0242	peptide deformylase activity
FY142_RS05845	COG2202	Pas domain
FY142_RS05845	COG2205	protein histidine kinase activity
FY142_RS05855	COG0321	lipoyl(octanoyl) transferase activity
FY142_RS05860	COG1064	alcohol dehydrogenase
FY142_RS05890	COG1862	Preprotein translocase
FY142_RS05910	COG2124	cytochrome p450
FY142_RS05925	COG0596	Alpha beta hydrolase
FY142_RS05935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY142_RS05940	COG0626	cystathionine gamma-synthase activity
FY142_RS05945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS05950	COG4597	amino acid ABC transporter
FY142_RS05955	COG0765	amino acid transport
FY142_RS05960	COG1126	abc transporter atp-binding protein
FY142_RS05975	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY142_RS05990	COG0436	Aminotransferase
FY142_RS06020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY142_RS06030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY142_RS06035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY142_RS06040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY142_RS06055	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY142_RS06060	COG1489	DNA binding
FY142_RS06065	COG0024	Methionine aminopeptidase
FY142_RS06070	COG2003	Belongs to the UPF0758 family
FY142_RS06085	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY142_RS06110	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY142_RS06115	COG0546	phosphoglycolate phosphatase activity
FY142_RS06125	COG0114	fumarate hydratase activity
FY142_RS06135	COG0504	CTP synthase activity
FY142_RS06145	COG0149	triose-phosphate isomerase activity
FY142_RS06155	COG0187	DNA topoisomerase II activity
FY142_RS06165	COG0740	serine-type endopeptidase activity
FY142_RS06175	COG0640	Transcriptional regulator
FY142_RS06180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY142_RS06185	COG0745	RESPONSE REGULATOR receiver
FY142_RS06200	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY142_RS06200	COG3264	Mechanosensitive ion channel
FY142_RS06265	COG1127	ABC transporter
FY142_RS06270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY142_RS06275	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_RS06285	COG0281	malic enzyme
FY142_RS06285	COG0280	phosphate acetyltransferase
FY142_RS06295	COG0778	Nitroreductase
FY142_RS06300	COG0823	Involved in the tonB-independent uptake of proteins
FY142_RS06315	COG1368	sulfuric ester hydrolase activity
FY142_RS06340	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY142_RS06360	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY142_RS06380	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY142_RS06395	COG0318	PFAM AMP-dependent synthetase and ligase
FY142_RS06405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY142_RS06405	COG0512	Glutamine amidotransferase of anthranilate synthase
FY142_RS06410	COG0343	queuine tRNA-ribosyltransferase activity
FY142_RS06415	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY142_RS06430	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY142_RS06450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY142_RS06455	COG0134	indole-3-glycerol-phosphate synthase activity
FY142_RS06460	COG0315	cyclic pyranopterin monophosphate synthase activity
FY142_RS06465	COG0303	'Molybdopterin
FY142_RS06470	COG3706	GGDEF domain
FY142_RS06480	COG0475	glutathione-regulated potassium exporter activity
FY142_RS06480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY142_RS06490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY142_RS06500	COG2814	Major facilitator Superfamily
FY142_RS06505	COG0746	molybdenum cofactor guanylyltransferase activity
FY142_RS06510	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY142_RS06515	COG0739	heme binding
FY142_RS06520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY142_RS06525	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY142_RS06530	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY142_RS06535	COG0805	protein transport
FY142_RS06540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY142_RS06545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY142_RS06550	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY142_RS06555	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY142_RS06560	COG1472	Belongs to the glycosyl hydrolase 3 family
FY142_RS06570	COG0018	arginyl-trna synthetase
FY142_RS06575	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY142_RS06600	COG0525	valine-tRNA ligase activity
FY142_RS06610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY142_RS06750	COG1525	nuclease
FY142_RS06825	COG3567	Phage-associated protein, HI1409 family
FY142_RS06875	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY142_RS07060	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY142_RS07065	COG1058	Belongs to the CinA family
FY142_RS07065	COG1546	Belongs to the CinA family
FY142_RS07070	COG0589	response to stress
FY142_RS07075	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY142_RS07090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY142_RS07100	COG0640	Transcriptional regulator
FY142_RS07105	COG1914	H( )-stimulated, divalent metal cation uptake system
FY142_RS07115	COG1132	(ABC) transporter
FY142_RS07120	COG0628	permease
FY142_RS07155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY142_RS07165	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY142_RS07175	COG0302	gtp cyclohydrolase
FY142_RS07180	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY142_RS07185	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY142_RS07195	COG0516	GMP reductase activity
FY142_RS07195	COG0517	IMP dehydrogenase activity
FY142_RS07230	COG1760	l-serine dehydratase
FY142_RS07270	COG0583	DNA-binding transcription factor activity
FY142_RS07285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY142_RS07285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY142_RS07295	COG0347	Belongs to the P(II) protein family
FY142_RS07300	COG0174	glutamine synthetase
FY142_RS07330	COG0697	spore germination
FY142_RS07340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY142_RS07350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY142_RS07380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY142_RS07390	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY142_RS07395	COG2186	Transcriptional regulator
FY142_RS07405	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY142_RS07410	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY142_RS07415	COG3845	ABC transporter
FY142_RS07420	COG1183	phosphatidylcholine synthase activity
FY142_RS07425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY142_RS07430	COG0679	Auxin Efflux Carrier
FY142_RS07435	COG0785	Cytochrome C biogenesis protein
FY142_RS07455	COG1278	Cold shock
FY142_RS07510	COG0577	efflux transmembrane transporter activity
FY142_RS07510	COG1136	(ABC) transporter
FY142_RS07515	COG0577	efflux transmembrane transporter activity
FY142_RS07515	COG1136	(ABC) transporter
FY142_RS07540	COG2151	metal-sulfur cluster biosynthetic enzyme
FY142_RS07545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY142_RS07550	COG0719	Fe-S assembly protein
FY142_RS07555	COG0396	ATPase activity
FY142_RS07560	COG0719	Fe-S assembly protein
FY142_RS07565	COG1104	cysteine desulfurase activity
FY142_RS07570	COG2945	thiolester hydrolase activity
FY142_RS07575	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY142_RS07580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY142_RS07590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY142_RS07595	COG2833	Protein of unknown function (DUF455)
FY142_RS07600	COG0739	heme binding
FY142_RS07605	COG0513	Belongs to the DEAD box helicase family
FY142_RS07630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY142_RS07640	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY142_RS07645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY142_RS07650	COG0047	phosphoribosylformylglycinamidine synthase activity
FY142_RS07665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY142_RS07670	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY142_RS07690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY142_RS07695	COG2814	Major facilitator Superfamily
FY142_RS07700	COG0483	inositol monophosphate 1-phosphatase activity
FY142_RS07705	COG0483	inositol monophosphate 1-phosphatase activity
FY142_RS07710	COG0037	tRNA processing
FY142_RS07715	COG2066	Belongs to the glutaminase family
FY142_RS07720	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY142_RS07725	COG0861	Integral membrane protein TerC family
FY142_RS07740	COG1280	lysine exporter protein (LysE YggA)
FY142_RS07750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY142_RS07755	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY142_RS07765	COG0538	isocitrate dehydrogenase activity
FY142_RS07775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY142_RS07780	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY142_RS07785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_RS07790	COG2313	pseudouridylate synthase activity
FY142_RS07800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS07805	COG4215	(ABC) transporter
FY142_RS07815	COG5425	PFAM Usg family protein
FY142_RS07825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY142_RS07830	COG1522	sequence-specific DNA binding
FY142_RS07835	COG1573	uracil-dna glycosylase
FY142_RS07845	COG2205	protein histidine kinase activity
FY142_RS07845	COG2202	Pas domain
FY142_RS07850	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY142_RS07855	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY142_RS07860	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY142_RS07875	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY142_RS07880	COG0842	Transport permease protein
FY142_RS07885	COG1131	(ABC) transporter
FY142_RS07890	COG0730	response to heat
FY142_RS07890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY142_RS07910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY142_RS07915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY142_RS07935	COG0129	dihydroxy-acid dehydratase activity
FY142_RS07940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY142_RS07945	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY142_RS07955	COG3739	integral membrane protein
FY142_RS07960	COG0203	ribosomal protein L17
FY142_RS07965	COG0202	RNA polymerase activity
FY142_RS07970	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY142_RS07975	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY142_RS07980	COG0563	adenylate kinase activity
FY142_RS07985	COG0201	protein transport
FY142_RS07990	COG0200	Binds to the 23S rRNA
FY142_RS07995	COG1841	ribosomal large subunit assembly
FY142_RS08000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY142_RS08005	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY142_RS08010	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY142_RS08015	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY142_RS08020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY142_RS08025	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY142_RS08030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY142_RS08035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY142_RS08040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY142_RS08045	COG0255	Belongs to the universal ribosomal protein uL29 family
FY142_RS08050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY142_RS08055	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY142_RS08060	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY142_RS08065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY142_RS08070	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY142_RS08075	COG0089	rRNA binding
FY142_RS08080	COG0088	Forms part of the polypeptide exit tunnel
FY142_RS08085	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY142_RS08090	COG0051	transcription antitermination factor activity, RNA binding
FY142_RS08095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY142_RS08100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY142_RS08105	COG0049	tRNA binding
FY142_RS08110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY142_RS08130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY142_RS08135	COG0085	RNA polymerase activity
FY142_RS08140	COG0222	ribosome binding
FY142_RS08145	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY142_RS08150	COG0081	regulation of translation
FY142_RS08155	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY142_RS08165	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY142_RS08175	COG1086	Polysaccharide biosynthesis protein
FY142_RS08180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY142_RS08185	COG0861	Integral membrane protein TerC family
FY142_RS08190	COG3895	Periplasmic Protein
FY142_RS08210	COG1132	(ABC) transporter
FY142_RS08215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY142_RS08235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY142_RS08270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS08270	COG2198	Histidine kinase
FY142_RS08270	COG2205	protein histidine kinase activity
FY142_RS08270	COG0784	Response regulator, receiver
FY142_RS08275	COG0784	Response regulator, receiver
FY142_RS08280	COG2202	Pas domain
FY142_RS08280	COG3920	Histidine kinase
FY142_RS08285	COG0784	Response regulator, receiver
FY142_RS08290	COG4251	negative regulation of phosphorylation
FY142_RS08305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY142_RS08310	COG1607	acyl-coa hydrolase
FY142_RS08330	COG2910	NAD(P)H-binding
FY142_RS08335	COG1733	regulation of RNA biosynthetic process
FY142_RS08350	COG0556	nucleotide-excision repair
FY142_RS08360	COG2382	esterase
FY142_RS08380	COG0484	heat shock protein binding
FY142_RS08400	COG3706	GGDEF domain
FY142_RS08420	COG1840	ABC-type Fe3 transport system, periplasmic component
FY142_RS08425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY142_RS08440	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY142_RS08450	COG2207	Transcriptional regulator
FY142_RS08455	COG1064	alcohol dehydrogenase
FY142_RS08460	COG1252	NADH dehydrogenase
FY142_RS08465	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY142_RS08470	COG2197	response regulator
FY142_RS08475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY142_RS08510	COG0656	L-ascorbic acid biosynthetic process
FY142_RS08525	COG0440	acetolactate synthase activity
FY142_RS08530	COG0028	Belongs to the TPP enzyme family
FY142_RS08540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY142_RS08545	COG0560	Phosphoserine phosphatase
FY142_RS08545	COG3830	Belongs to the UPF0237 family
FY142_RS08565	COG0330	HflC and HflK could
FY142_RS08570	COG0330	HflC and HflK could
FY142_RS08580	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY142_RS08615	COG0277	FAD linked oxidase domain protein
FY142_RS08620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY142_RS08660	COG1335	isochorismatase
FY142_RS08690	COG2264	protein methyltransferase activity
FY142_RS08695	COG1999	signal sequence binding
FY142_RS08705	COG0835	chemotaxis
FY142_RS08715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY142_RS08720	COG0583	DNA-binding transcription factor activity
FY142_RS08730	COG1247	-acetyltransferase
FY142_RS08740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY142_RS08745	COG0497	DNA recombination
FY142_RS08750	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY142_RS08760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY142_RS08765	COG0849	cell division
FY142_RS08770	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY142_RS08775	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY142_RS08780	COG0477	Major facilitator Superfamily
FY142_RS08785	COG5001	Diguanylate cyclase
FY142_RS08790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY142_RS08795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY142_RS08800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY142_RS08810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY142_RS08815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY142_RS08825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY142_RS08840	COG0275	rRNA processing
FY142_RS08845	COG2001	Belongs to the MraZ family
FY142_RS08870	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY142_RS08900	COG4106	trans-aconitate 2-methyltransferase activity
FY142_RS08920	COG2226	methyltransferase
FY142_RS08930	COG2267	carboxylic ester hydrolase activity
FY142_RS08935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY142_RS08950	COG0251	oxidation-reduction process
FY142_RS08965	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_RS08970	COG2814	Major facilitator Superfamily
FY142_RS09000	COG1012	belongs to the aldehyde dehydrogenase family
FY142_RS09005	COG0174	glutamine synthetase
FY142_RS09010	COG0531	amino acid
FY142_RS09020	COG1737	Transcriptional regulator
FY142_RS09025	COG2182	Extracellular solute-binding protein
FY142_RS09040	COG3842	ATPase activity
FY142_RS09100	COG2968	Membrane
FY142_RS09110	COG0432	Pfam Uncharacterised protein family UPF0047
FY142_RS09125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY142_RS09130	COG0358	DNA primase activity
FY142_RS09150	COG0505	Belongs to the CarA family
FY142_RS09155	COG0534	Mate efflux family protein
FY142_RS09170	COG2321	neutral zinc metallopeptidase
FY142_RS09185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY142_RS09195	COG3706	GGDEF domain
FY142_RS09210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY142_RS09220	COG1522	sequence-specific DNA binding
FY142_RS09225	COG0492	ferredoxin-NADP+ reductase activity
FY142_RS09230	COG0583	DNA-binding transcription factor activity
FY142_RS09240	COG1902	pentaerythritol trinitrate reductase activity
FY142_RS09265	COG0387	Pfam Sodium calcium exchanger
FY142_RS09270	COG0436	Aminotransferase
FY142_RS09275	COG2200	EAL domain
FY142_RS09275	COG2199	diguanylate cyclase activity
FY142_RS09290	COG1278	Cold shock
FY142_RS09295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY142_RS09305	COG1846	Transcriptional regulator
FY142_RS09310	COG0745	RESPONSE REGULATOR receiver
FY142_RS09320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY142_RS09340	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY142_RS09350	COG1496	oxidoreductase activity
FY142_RS09365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY142_RS09375	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY142_RS09390	COG0840	transmembrane signaling receptor activity
FY142_RS09395	COG1012	belongs to the aldehyde dehydrogenase family
FY142_RS09400	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY142_RS09405	COG3300	MHYT domain
FY142_RS09405	COG5001	Diguanylate cyclase
FY142_RS09410	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY142_RS09415	COG5001	Diguanylate cyclase
FY142_RS09425	COG0193	aminoacyl-tRNA hydrolase activity
FY142_RS09435	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY142_RS09460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY142_RS09470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY142_RS09470	COG2857	Cytochrome c1
FY142_RS09490	COG1132	(ABC) transporter
FY142_RS09500	COG1132	(ABC) transporter
FY142_RS09510	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY142_RS09525	COG0408	coproporphyrinogen oxidase activity
FY142_RS09540	COG0617	tRNA 3'-terminal CCA addition
FY142_RS09555	COG0714	Associated with various cellular activities
FY142_RS09575	COG0454	-acetyltransferase
FY142_RS09590	COG0477	Major facilitator Superfamily
FY142_RS09600	COG0435	Glutathione S-transferase
FY142_RS09605	COG0494	nUDIX hydrolase
FY142_RS09615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY142_RS09620	COG3135	benzoate transporter
FY142_RS09645	COG0740	serine-type endopeptidase activity
FY142_RS09660	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY142_RS09665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY142_RS09690	COG4175	Glycine betaine
FY142_RS09710	COG1435	thymidine kinase activity
FY142_RS09735	COG1629	transport
FY142_RS09735	COG4771	TonB-dependent receptor
FY142_RS09745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY142_RS09745	COG0512	Glutamine amidotransferase of anthranilate synthase
FY142_RS09760	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY142_RS09770	COG0366	Alpha amylase catalytic
FY142_RS09775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_RS09795	COG1160	GTP binding
FY142_RS09815	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY142_RS09825	COG0024	Methionine aminopeptidase
FY142_RS09835	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS09855	COG0583	DNA-binding transcription factor activity
FY142_RS09870	COG0402	S-adenosylhomocysteine deaminase activity
FY142_RS09880	COG1304	FMN binding
FY142_RS09890	COG1309	transcriptional regulator
FY142_RS09895	COG1686	Belongs to the peptidase S11 family
FY142_RS09905	COG2351	hydroxyisourate hydrolase activity
FY142_RS09910	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY142_RS09935	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY142_RS09945	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY142_RS09945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS09955	COG0513	Belongs to the DEAD box helicase family
FY142_RS09965	COG2259	Doxx family
FY142_RS09970	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_RS09980	COG2308	Evidence 4 Homologs of previously reported genes of
FY142_RS09990	COG1305	Transglutaminase-like
FY142_RS10015	COG4214	carbohydrate transport
FY142_RS10025	COG4213	ABC transporter substrate-binding protein
FY142_RS10080	COG2948	multi-organism process
FY142_RS10090	COG3701	Conjugal transfer protein
FY142_RS10095	COG3846	protein secretion by the type IV secretion system
FY142_RS10110	COG3451	type IV secretory pathway VirB4
FY142_RS10125	COG4962	Type ii secretion system protein e
FY142_RS10150	COG0583	DNA-binding transcription factor activity
FY142_RS10160	COG1566	PFAM secretion protein HlyD family protein
FY142_RS10175	COG2207	Transcriptional regulator
FY142_RS10180	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS10190	COG0583	DNA-binding transcription factor activity
FY142_RS10200	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY142_RS10210	COG0583	DNA-binding transcription factor activity
FY142_RS10245	COG1192	Involved in chromosome partitioning
FY142_RS10285	COG2814	Major facilitator Superfamily
FY142_RS10295	COG5489	Protein of unknown function (DUF736)
FY142_RS10310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY142_RS10340	COG1204	response to ionizing radiation
FY142_RS10355	COG0514	ATP-dependent DNA helicase (RecQ)
FY142_RS10405	COG0583	DNA-binding transcription factor activity
FY142_RS10410	COG1902	pentaerythritol trinitrate reductase activity
FY142_RS10415	COG0583	DNA-binding transcription factor activity
FY142_RS10430	COG1335	isochorismatase
FY142_RS10435	COG0583	DNA-binding transcription factor activity
FY142_RS10440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY142_RS10450	COG4584	PFAM Integrase catalytic
FY142_RS10465	COG0840	transmembrane signaling receptor activity
FY142_RS10480	COG0646	methionine synthase
FY142_RS10480	COG1410	methionine synthase
FY142_RS10495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS10525	COG1215	transferase activity, transferring glycosyl groups
FY142_RS10555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY142_RS10570	COG2346	COG2346, Truncated hemoglobins
FY142_RS10590	COG1309	transcriptional regulator
FY142_RS10605	COG0494	nUDIX hydrolase
FY142_RS10615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_RS10620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_RS10650	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY142_RS10655	COG0830	nickel cation binding
FY142_RS10660	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY142_RS10675	COG0804	urea catabolic process
FY142_RS10680	COG1442	glycosyl transferase family 8
FY142_RS10685	COG3755	Protein conserved in bacteria
FY142_RS10695	COG0832	Belongs to the urease beta subunit family
FY142_RS10700	COG3813	Protein conserved in bacteria
FY142_RS10705	COG0831	urea catabolic process
FY142_RS10710	COG0829	nickel cation binding
FY142_RS10740	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY142_RS10760	COG0174	glutamine synthetase
FY142_RS10765	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS10770	COG0784	Response regulator, receiver
FY142_RS10770	COG5002	protein histidine kinase activity
FY142_RS10770	COG2198	Histidine kinase
FY142_RS10785	COG0726	polysaccharide deacetylase
FY142_RS10820	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY142_RS10895	COG0564	pseudouridine synthase activity
FY142_RS10905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY142_RS10915	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY142_RS10940	COG0346	lactoylglutathione lyase activity
FY142_RS10950	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY142_RS10960	COG2832	Protein of unknown function (DUF454)
FY142_RS10965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY142_RS10970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_RS10975	COG4558	Periplasmic binding protein
FY142_RS10985	COG3721	Heme iron utilization protein
FY142_RS11000	COG3655	Transcriptional regulator
FY142_RS11025	COG2205	protein histidine kinase activity
FY142_RS11065	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_RS11070	COG4605	iron ion homeostasis
FY142_RS11075	COG4604	ABC transporter, ATP-binding protein
FY142_RS11080	COG0783	Belongs to the Dps family
FY142_RS11095	COG2972	Histidine kinase
FY142_RS11095	COG0840	transmembrane signaling receptor activity
FY142_RS11100	COG0656	L-ascorbic acid biosynthetic process
FY142_RS11105	COG2814	Major facilitator Superfamily
FY142_RS11115	COG0583	DNA-binding transcription factor activity
FY142_RS11120	COG0657	acetylesterase activity
FY142_RS11125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_RS11145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY142_RS11150	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY142_RS11155	COG0288	reversible hydration of carbon dioxide
FY142_RS11165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY142_RS11185	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY142_RS11190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY142_RS11195	COG0778	Nitroreductase
FY142_RS11200	COG2267	carboxylic ester hydrolase activity
FY142_RS11205	COG0251	oxidation-reduction process
FY142_RS11210	COG1335	isochorismatase
FY142_RS11215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS11225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_RS11240	COG1175	transmembrane transport
FY142_RS11245	COG0395	ABC-type sugar transport system, permease component
FY142_RS11250	COG3842	ATPase activity
FY142_RS11255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_RS11265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY142_RS11280	COG4608	Belongs to the ABC transporter superfamily
FY142_RS11285	COG0444	Belongs to the ABC transporter superfamily
FY142_RS11290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS11295	COG0601	transmembrane transport
FY142_RS11350	COG2159	amidohydrolase
FY142_RS11355	COG1960	acyl-CoA dehydrogenase activity
FY142_RS11385	COG0745	RESPONSE REGULATOR receiver
FY142_RS11395	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY142_RS11395	COG1902	pentaerythritol trinitrate reductase activity
FY142_RS11400	COG3842	ATPase activity
FY142_RS11410	COG1840	ABC-type Fe3 transport system, periplasmic component
FY142_RS11415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY142_RS11420	COG0745	RESPONSE REGULATOR receiver
FY142_RS11430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY142_RS11435	COG0583	DNA-binding transcription factor activity
FY142_RS11440	COG1278	Cold shock
FY142_RS11475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY142_RS11480	COG1309	transcriptional regulator
FY142_RS11485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_RS11490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY142_RS11500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY142_RS11505	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY142_RS11525	COG0583	DNA-binding transcription factor activity
FY142_RS11530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS11535	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY142_RS11540	COG4149	molybdate abc transporter
FY142_RS11545	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY142_RS11560	COG2022	thiamine diphosphate biosynthetic process
FY142_RS11575	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY142_RS11580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY142_RS11590	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY142_RS11610	COG1132	(ABC) transporter
FY142_RS11615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY142_RS11660	COG4166	transmembrane transport
FY142_RS11665	COG0601	transmembrane transport
FY142_RS11670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS11685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY142_RS11690	COG3142	Participates in the control of copper homeostasis
FY142_RS11695	COG2814	Major facilitator Superfamily
FY142_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS11715	COG1737	Transcriptional regulator
FY142_RS11725	COG3842	ATPase activity
FY142_RS11735	COG0395	ABC-type sugar transport system, permease component
FY142_RS11755	COG2188	Transcriptional regulator
FY142_RS11760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY142_RS11765	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY142_RS11770	COG1940	carbohydrate kinase activity
FY142_RS11780	COG0671	phosphoesterase, PA-phosphatase related
FY142_RS11785	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY142_RS11790	COG0156	8-amino-7-oxononanoate synthase activity
FY142_RS11800	COG0729	surface antigen
FY142_RS11810	COG0835	chemotaxis
FY142_RS11820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY142_RS11825	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY142_RS11830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY142_RS11835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY142_RS11840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY142_RS11845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY142_RS11860	COG4974	Belongs to the 'phage' integrase family
FY142_RS11885	COG1280	lysine exporter protein (LysE YggA)
FY142_RS11895	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY142_RS11900	COG0567	Dehydrogenase, E1 component
FY142_RS11905	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY142_RS11910	COG0045	succinate-CoA ligase (ADP-forming) activity
FY142_RS11915	COG0039	L-malate dehydrogenase activity
FY142_RS11920	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY142_RS11970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY142_RS11975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY142_RS11980	COG0181	hydroxymethylbilane synthase activity
FY142_RS12020	COG1872	DUF167
FY142_RS12025	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY142_RS12035	COG1217	gtp-binding protein TYPA
FY142_RS12040	COG0339	signal peptide processing
FY142_RS12045	COG1846	Transcriptional regulator
FY142_RS12055	COG0137	argininosuccinate synthase activity
FY142_RS12065	COG1280	lysine exporter protein (LysE YggA)
FY142_RS12070	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY142_RS12075	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY142_RS12085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY142_RS12100	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY142_RS12105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY142_RS12110	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY142_RS12120	COG4181	ATPase activity
FY142_RS12130	COG0670	Belongs to the BI1 family
FY142_RS12145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY142_RS12150	COG4133	protoheme IX ABC transporter activity
FY142_RS12155	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY142_RS12160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY142_RS12185	COG2917	probably involved in intracellular septation
FY142_RS12190	COG0552	protein localization to endoplasmic reticulum
FY142_RS12195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY142_RS12200	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY142_RS12215	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY142_RS12220	COG0287	Prephenate dehydrogenase
FY142_RS12220	COG1605	Chorismate mutase
FY142_RS12225	COG0228	four-way junction DNA binding
FY142_RS12230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY142_RS12235	COG0336	Belongs to the RNA methyltransferase TrmD family
FY142_RS12245	COG0335	large ribosomal subunit rRNA binding
FY142_RS12250	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY142_RS12255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_RS12270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY142_RS12290	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY142_RS12310	COG0488	(ABC) transporter
FY142_RS12320	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY142_RS12330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY142_RS12335	COG0142	geranyltranstransferase activity
FY142_RS12340	COG2885	chlorophyll binding
FY142_RS12345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY142_RS12350	COG2223	nitrite transmembrane transporter activity
FY142_RS12355	COG1349	DNA-binding transcription factor activity
FY142_RS12360	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY142_RS12365	COG2197	response regulator
FY142_RS12370	COG1132	(ABC) transporter
FY142_RS12380	COG3459	Glycosyltransferase 36 associated
FY142_RS12385	COG1473	amidohydrolase
FY142_RS12395	COG0579	oxidoreductase
FY142_RS12405	COG0129	dihydroxy-acid dehydratase activity
FY142_RS12410	COG2084	Dehydrogenase
FY142_RS12415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_RS12420	COG0277	FAD linked oxidase domain protein
FY142_RS12425	COG2186	Transcriptional regulator
FY142_RS12435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY142_RS12440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY142_RS12445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY142_RS12450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY142_RS12460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY142_RS12465	COG0495	leucyl-tRNA aminoacylation
FY142_RS12480	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY142_RS12485	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY142_RS12500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY142_RS12505	COG1946	Acyl-CoA thioesterase
FY142_RS12510	COG0347	Belongs to the P(II) protein family
FY142_RS12515	COG0004	ammonium transporteR
FY142_RS12520	COG1674	ftsk spoiiie
FY142_RS12525	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY142_RS12540	COG0745	RESPONSE REGULATOR receiver
FY142_RS12550	COG1329	Transcriptional regulator
FY142_RS12560	COG2270	Major facilitator Superfamily
FY142_RS12575	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS12590	COG0494	nUDIX hydrolase
FY142_RS12595	COG2861	carbohydrate metabolic process
FY142_RS12600	COG0793	Belongs to the peptidase S41A family
FY142_RS12610	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY142_RS12615	COG0799	negative regulation of ribosome biogenesis
FY142_RS12620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY142_RS12625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY142_RS12630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY142_RS12635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY142_RS12650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY142_RS12655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY142_RS12680	COG0066	3-isopropylmalate dehydratase activity
FY142_RS12685	COG0473	3-isopropylmalate dehydrogenase activity
FY142_RS12690	COG1858	cytochrome C peroxidase
FY142_RS12695	COG1797	cobyrinic acid a,c-diamide synthase activity
FY142_RS12705	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY142_RS12770	COG1492	cobalamin metabolic process
FY142_RS12785	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_RS12790	COG3254	rhamnose metabolic process
FY142_RS12795	COG0246	Mannitol dehydrogenase
FY142_RS12800	COG1063	alcohol dehydrogenase
FY142_RS12825	COG1129	ABC transporter
FY142_RS12830	COG2186	Transcriptional regulator
FY142_RS12835	COG2721	sulfolactate sulfo-lyase activity
FY142_RS12840	COG0138	bifunctional purine biosynthesis protein purh
FY142_RS12850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY142_RS12850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY142_RS12855	COG0501	Belongs to the peptidase M48B family
FY142_RS12875	COG0357	Ribosomal RNA small subunit methyltransferase G
FY142_RS12880	COG0445	tRNA wobble uridine modification
FY142_RS12885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY142_RS12890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY142_RS12895	COG1981	membrane
FY142_RS12900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY142_RS12905	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY142_RS12910	COG0424	maF-like protein
FY142_RS12915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY142_RS12920	COG0237	dephospho-CoA kinase activity
FY142_RS12930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY142_RS12935	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY142_RS12945	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY142_RS12970	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY142_RS12985	COG0135	phosphoribosylanthranilate isomerase activity
FY142_RS12990	COG0133	tryptophan synthase activity
FY142_RS12995	COG0159	tryptophan synthase activity
FY142_RS13000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY142_RS13015	COG1074	ATP-dependent DNA helicase activity
FY142_RS13025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY142_RS13030	COG0802	atpase or kinase
FY142_RS13035	COG2205	protein histidine kinase activity
FY142_RS13040	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY142_RS13045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY142_RS13050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY142_RS13050	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY142_RS13055	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY142_RS13060	COG0642	Histidine kinase
FY142_RS13065	COG0745	RESPONSE REGULATOR receiver
FY142_RS13070	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY142_RS13080	COG1652	LysM domain
FY142_RS13085	COG1072	(Pantothenic acid kinase))
FY142_RS13090	COG0140	phosphoribosyl-ATP diphosphatase activity
FY142_RS13095	COG0107	imidazoleglycerol-phosphate synthase activity
FY142_RS13100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY142_RS13105	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY142_RS13115	COG0131	Imidazoleglycerol-phosphate dehydratase
FY142_RS13120	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY142_RS13125	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY142_RS13135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY142_RS13150	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY142_RS13160	COG1643	Atp-dependent helicase
FY142_RS13205	COG1940	carbohydrate kinase activity
FY142_RS13225	COG1072	(Pantothenic acid kinase))
FY142_RS13235	COG1780	Probably involved in ribonucleotide reductase function
FY142_RS13255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY142_RS13285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_RS13295	COG2813	Specifically methylates the guanine in position
FY142_RS13300	COG1185	polyribonucleotide nucleotidyltransferase activity
FY142_RS13305	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY142_RS13310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY142_RS13315	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY142_RS13320	COG3064	Membrane
FY142_RS13320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY142_RS13335	COG0779	Required for maturation of 30S ribosomal subunits
FY142_RS13340	COG2814	Major facilitator Superfamily
FY142_RS13350	COG2951	lytic endotransglycosylase activity
FY142_RS13355	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY142_RS13365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY142_RS13370	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY142_RS13385	COG2816	NAD+ diphosphatase activity
FY142_RS13390	COG0077	Prephenate dehydratase
FY142_RS13390	COG1605	Chorismate mutase
FY142_RS13395	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY142_RS13400	COG3474	cytochrome
FY142_RS13410	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY142_RS13415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY142_RS13420	COG1278	Cold shock
FY142_RS13425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY142_RS13435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY142_RS13435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY142_RS13440	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY142_RS13470	COG2900	Belongs to the SlyX family
FY142_RS13480	COG0484	heat shock protein binding
FY142_RS13485	COG0443	Heat shock 70 kDa protein
FY142_RS13500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY142_RS13505	COG1744	ABC transporter substrate-binding protein PnrA-like
FY142_RS13510	COG3845	ABC transporter
FY142_RS13515	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY142_RS13520	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY142_RS13525	COG0295	cytidine deaminase activity
FY142_RS13530	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY142_RS13535	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY142_RS13540	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY142_RS13550	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY142_RS13555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY142_RS13560	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY142_RS13570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY142_RS13575	COG1845	cytochrome c oxidase, subunit III
FY142_RS13580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY142_RS13585	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY142_RS13590	COG0477	Major facilitator Superfamily
FY142_RS13595	COG0067	glutamate synthase
FY142_RS13595	COG0069	glutamate synthase activity
FY142_RS13595	COG0070	glutamate synthase
FY142_RS13600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY142_RS13615	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY142_RS13625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY142_RS13655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_RS13675	COG0848	biopolymer transport protein
FY142_RS13685	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY142_RS13700	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY142_RS13705	COG3454	Phosphonate metabolism
FY142_RS13710	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY142_RS13715	COG3639	organic phosphonate transmembrane transporter activity
FY142_RS13720	COG3639	organic phosphonate transmembrane transporter activity
FY142_RS13730	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY142_RS13740	COG4778	phosphonate C-P lyase system protein PhnL
FY142_RS13745	COG4107	phosphonate C-P lyase system protein PhnK
FY142_RS13750	COG3627	carbon phosphorus lyase activity
FY142_RS13755	COG3626	phosphonate metabolism
FY142_RS13760	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY142_RS13765	COG3624	Phosphonate C-P lyase system protein PhnG
FY142_RS13770	COG2188	Transcriptional regulator
FY142_RS13775	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY142_RS13780	COG0837	glucose binding
FY142_RS13785	COG1803	Methylglyoxal synthase
FY142_RS13790	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY142_RS13795	COG4166	transmembrane transport
FY142_RS13800	COG4174	ABC transporter (Permease)
FY142_RS13805	COG4239	(ABC) transporter, permease
FY142_RS13810	COG4172	Belongs to the ABC transporter superfamily
FY142_RS13815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS13820	COG0174	glutamine synthetase
FY142_RS13825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS13830	COG3265	gluconokinase activity
FY142_RS13835	COG1174	glycine betaine transport
FY142_RS13840	COG1125	glycine betaine transport
FY142_RS13845	COG1174	glycine betaine transport
FY142_RS13850	COG1732	Glycine betaine
FY142_RS13860	COG1959	2 iron, 2 sulfur cluster binding
FY142_RS13865	COG1840	ABC-type Fe3 transport system, periplasmic component
FY142_RS13875	COG4269	membrane
FY142_RS13890	COG0697	spore germination
FY142_RS13905	COG0791	NLP P60 protein
FY142_RS13915	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY142_RS13920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY142_RS13955	COG4964	Belongs to the GSP D family
FY142_RS14000	COG3422	double-strand break repair
FY142_RS14005	COG3757	hydrolase, family 25
FY142_RS14010	COG0697	spore germination
FY142_RS14015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY142_RS14030	COG0492	ferredoxin-NADP+ reductase activity
FY142_RS14045	COG0481	GTPase activity
FY142_RS14050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY142_RS14065	COG1396	sequence-specific DNA binding
FY142_RS14080	COG1917	Cupin 2, conserved barrel domain protein
FY142_RS14080	COG2169	Transcriptional regulator
FY142_RS14085	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY142_RS14110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY142_RS14115	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY142_RS14120	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY142_RS14130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY142_RS14135	COG0072	phenylalanine-tRNA ligase activity
FY142_RS14135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY142_RS14140	COG0667	Aldo Keto reductase
FY142_RS14160	COG4977	sequence-specific DNA binding
FY142_RS14185	COG1570	exodeoxyribonuclease VII activity
FY142_RS14190	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_RS14200	COG1846	Transcriptional regulator
FY142_RS14210	COG2309	aminopeptidase activity
FY142_RS14220	COG1393	Belongs to the ArsC family
FY142_RS14240	COG1309	transcriptional regulator
FY142_RS14250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY142_RS14250	COG0519	Catalyzes the synthesis of GMP from XMP
FY142_RS14265	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY142_RS14295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY142_RS14305	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY142_RS14315	COG1968	undecaprenyl-diphosphatase activity
FY142_RS14330	COG0284	orotidine-5'-phosphate decarboxylase activity
FY142_RS14340	COG3963	phosphatidate phosphatase activity
FY142_RS14350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY142_RS14355	COG0792	nuclease activity
FY142_RS14370	COG1175	transmembrane transport
FY142_RS14375	COG0395	ABC-type sugar transport system, permease component
FY142_RS14380	COG3842	ATPase activity
FY142_RS14390	COG0189	ligase activity
FY142_RS14400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY142_RS14405	COG1280	lysine exporter protein (LysE YggA)
FY142_RS14410	COG0756	dUTP diphosphatase activity
FY142_RS14415	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY142_RS14420	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY142_RS14435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY142_RS14440	COG2226	methyltransferase
FY142_RS14445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY142_RS14450	COG1024	Enoyl-CoA hydratase
FY142_RS14455	COG0268	Binds directly to 16S ribosomal RNA
FY142_RS14465	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FY142_RS14495	COG1278	Cold shock
FY142_RS14530	COG0411	ABC transporter
FY142_RS14535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY142_RS14540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY142_RS14545	COG1454	alcohol dehydrogenase
FY142_RS14550	COG0747	negative chemotaxis
FY142_RS14555	COG0601	transmembrane transport
FY142_RS14565	COG4608	Belongs to the ABC transporter superfamily
FY142_RS14570	COG1349	DNA-binding transcription factor activity
FY142_RS14575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY142_RS14600	COG4302	ethanolamine ammonia-lyase activity
FY142_RS14605	COG0025	NhaP-type Na H and K H
FY142_RS14610	COG4106	trans-aconitate 2-methyltransferase activity
FY142_RS14620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS14625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS14630	COG0601	transmembrane transport
FY142_RS14655	COG4172	Belongs to the ABC transporter superfamily
FY142_RS14690	COG0596	Alpha beta hydrolase
FY142_RS14705	COG1764	response to oxidative stress
FY142_RS14715	COG0596	Alpha beta hydrolase
FY142_RS14735	COG0783	Belongs to the Dps family
FY142_RS14740	COG0243	molybdopterin cofactor binding
FY142_RS14750	COG4566	intracellular signal transduction
FY142_RS14755	COG4566	intracellular signal transduction
FY142_RS14785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY142_RS14795	COG1414	Transcriptional regulator
FY142_RS14810	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS14830	COG1522	sequence-specific DNA binding
FY142_RS14850	COG0628	permease
FY142_RS14860	COG2235	arginine
FY142_RS14895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY142_RS14905	COG0702	epimerase
FY142_RS14910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY142_RS14915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_RS14920	COG0745	RESPONSE REGULATOR receiver
FY142_RS14925	COG5002	protein histidine kinase activity
FY142_RS14940	COG2233	PERMEase
FY142_RS15000	COG0395	ABC-type sugar transport system, permease component
FY142_RS15005	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_RS15015	COG3842	ATPase activity
FY142_RS15050	COG1653	transport
FY142_RS15060	COG0395	ABC-type sugar transport system, permease component
FY142_RS15065	COG3842	ATPase activity
FY142_RS15080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY142_RS15085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_RS15090	COG1116	anion transmembrane transporter activity
FY142_RS15095	COG0395	ABC-type sugar transport system, permease component
FY142_RS15100	COG1175	transmembrane transport
FY142_RS15130	COG1609	Transcriptional regulator
FY142_RS15145	COG1082	Xylose isomerase domain protein TIM barrel
FY142_RS15150	COG3842	ATPase activity
FY142_RS15155	COG0395	ABC-type sugar transport system, permease component
FY142_RS15160	COG1175	transmembrane transport
FY142_RS15165	COG1653	transport
FY142_RS15170	COG1309	transcriptional regulator
FY142_RS15175	COG0673	inositol 2-dehydrogenase activity
FY142_RS15190	COG0673	inositol 2-dehydrogenase activity
FY142_RS15200	COG1278	Cold shock
FY142_RS15210	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY142_RS15235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY142_RS15240	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY142_RS15255	COG3842	ATPase activity
FY142_RS15260	COG0395	ABC-type sugar transport system, permease component
FY142_RS15265	COG1175	transmembrane transport
FY142_RS15275	COG3618	amidohydrolase
FY142_RS15280	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_RS15285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_RS15290	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS15295	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY142_RS15300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_RS15305	COG2186	Transcriptional regulator
FY142_RS15320	COG0667	Aldo Keto reductase
FY142_RS15350	COG4977	sequence-specific DNA binding
FY142_RS15355	COG2223	nitrite transmembrane transporter activity
FY142_RS15360	COG1609	Transcriptional regulator
FY142_RS15365	COG1063	alcohol dehydrogenase
FY142_RS15370	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS15380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_RS15385	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY142_RS15390	COG1175	transmembrane transport
FY142_RS15395	COG0395	ABC-type sugar transport system, permease component
FY142_RS15410	COG0395	ABC-type sugar transport system, permease component
FY142_RS15420	COG2182	Extracellular solute-binding protein
FY142_RS15425	COG0626	cystathionine gamma-synthase activity
FY142_RS15440	COG0454	-acetyltransferase
FY142_RS15445	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY142_RS15455	COG1121	(ABC) transporter
FY142_RS15460	COG0523	cobalamin synthesis protein
FY142_RS15475	COG0523	cobalamin synthesis protein
FY142_RS15480	COG1653	transport
FY142_RS15485	COG1175	transmembrane transport
FY142_RS15490	COG0395	ABC-type sugar transport system, permease component
FY142_RS15495	COG3842	ATPase activity
FY142_RS15505	COG3047	cAMP biosynthetic process
FY142_RS15530	COG0583	DNA-binding transcription factor activity
FY142_RS15535	COG1879	ABC-type sugar transport system periplasmic component
FY142_RS15540	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS15545	COG1129	ABC transporter
FY142_RS15555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY142_RS15560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_RS15570	COG3257	ureidoglycine aminohydrolase activity
FY142_RS15580	COG5001	Diguanylate cyclase
FY142_RS15585	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY142_RS15595	COG0747	negative chemotaxis
FY142_RS15600	COG0601	transmembrane transport
FY142_RS15605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS15615	COG4608	Belongs to the ABC transporter superfamily
FY142_RS15620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY142_RS15635	COG0346	lactoylglutathione lyase activity
FY142_RS15645	COG0129	dihydroxy-acid dehydratase activity
FY142_RS15650	COG1879	ABC-type sugar transport system periplasmic component
FY142_RS15655	COG1129	ABC transporter
FY142_RS15660	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS15665	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS15670	COG2186	Transcriptional regulator
FY142_RS15685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY142_RS15690	COG0587	DNA-directed DNA polymerase activity
FY142_RS15720	COG0673	inositol 2-dehydrogenase activity
FY142_RS15730	COG3842	ATPase activity
FY142_RS15735	COG0395	ABC-type sugar transport system, permease component
FY142_RS15740	COG1175	transmembrane transport
FY142_RS15745	COG1653	transport
FY142_RS15755	COG0673	inositol 2-dehydrogenase activity
FY142_RS15770	COG5001	Diguanylate cyclase
FY142_RS15780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS15785	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY142_RS15790	COG2894	cell division
FY142_RS15795	COG0850	regulation of cytokinetic process
FY142_RS15800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY142_RS15805	COG2186	Transcriptional regulator
FY142_RS15810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY142_RS15820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY142_RS15825	COG1063	alcohol dehydrogenase
FY142_RS15830	COG1312	Catalyzes the dehydration of D-mannonate
FY142_RS15850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY142_RS15855	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY142_RS15855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY142_RS15860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS15875	COG0625	glutathione transferase activity
FY142_RS15880	COG4172	Belongs to the ABC transporter superfamily
FY142_RS15885	COG1921	L-seryl-tRNASec selenium transferase activity
FY142_RS15900	COG3964	amidohydrolase
FY142_RS15910	COG0601	transmembrane transport
FY142_RS15915	COG0747	negative chemotaxis
FY142_RS15920	COG0438	transferase activity, transferring glycosyl groups
FY142_RS15955	COG4989	oxidoreductase activity
FY142_RS15965	COG2188	Transcriptional regulator
FY142_RS15970	COG3842	ATPase activity
FY142_RS15975	COG1653	transport
FY142_RS15980	COG1175	transmembrane transport
FY142_RS15985	COG0395	ABC-type sugar transport system, permease component
FY142_RS15990	COG1501	Belongs to the glycosyl hydrolase 31 family
FY142_RS16000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_RS16005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY142_RS16010	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY142_RS16015	COG0352	thiamine-phosphate diphosphorylase activity
FY142_RS16020	COG0351	phosphomethylpyrimidine kinase
FY142_RS16025	COG1522	sequence-specific DNA binding
FY142_RS16030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY142_RS16035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS16050	COG2204	response regulator
FY142_RS16055	COG4191	Histidine kinase
FY142_RS16060	COG1301	dicarboxylic acid transport
FY142_RS16065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY142_RS16070	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS16080	COG1473	amidohydrolase
FY142_RS16100	COG1215	transferase activity, transferring glycosyl groups
FY142_RS16110	COG2942	2-epimerase
FY142_RS16135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_RS16145	COG2197	response regulator
FY142_RS16175	COG3307	-O-antigen
FY142_RS16180	COG1596	polysaccharide export
FY142_RS16185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY142_RS16195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY142_RS16200	COG0840	transmembrane signaling receptor activity
FY142_RS16205	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_RS16215	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS16225	COG2094	Belongs to the DNA glycosylase MPG family
FY142_RS16240	COG1609	Transcriptional regulator
FY142_RS16245	COG1653	transport
FY142_RS16260	COG3842	ATPase activity
FY142_RS16270	COG0673	inositol 2-dehydrogenase activity
FY142_RS16275	COG0602	queuosine metabolic process
FY142_RS16280	COG0720	synthase
FY142_RS16285	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY142_RS16295	COG0673	inositol 2-dehydrogenase activity
FY142_RS16310	COG0395	ABC-type sugar transport system, permease component
FY142_RS16315	COG1175	transmembrane transport
FY142_RS16340	COG0583	DNA-binding transcription factor activity
FY142_RS16345	COG0280	phosphate acetyltransferase
FY142_RS16345	COG0281	malic enzyme
FY142_RS16360	COG0765	amino acid transport
FY142_RS16365	COG1126	abc transporter atp-binding protein
FY142_RS16370	COG2079	MmgE PrpD family protein
FY142_RS16375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS16385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS16400	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY142_RS16410	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY142_RS16415	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY142_RS16420	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS16425	COG1129	ABC transporter
FY142_RS16440	COG1473	amidohydrolase
FY142_RS16445	COG0747	negative chemotaxis
FY142_RS16460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS16465	COG0601	transmembrane transport
FY142_RS16470	COG0583	DNA-binding transcription factor activity
FY142_RS16475	COG1446	asparaginase
FY142_RS16490	COG0747	negative chemotaxis
FY142_RS16510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS16515	COG0601	transmembrane transport
FY142_RS16520	COG2197	response regulator
FY142_RS16525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY142_RS16530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_RS16540	COG3842	ATPase activity
FY142_RS16545	COG0395	ABC-type sugar transport system, permease component
FY142_RS16550	COG1175	transmembrane transport
FY142_RS16560	COG0673	inositol 2-dehydrogenase activity
FY142_RS16565	COG0673	inositol 2-dehydrogenase activity
FY142_RS16585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_RS16590	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY142_RS16610	COG1595	DNA-templated transcription, initiation
FY142_RS16615	COG1120	ATPase activity
FY142_RS16620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_RS16635	COG2226	methyltransferase
FY142_RS16645	COG1120	ATPase activity
FY142_RS16650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_RS16695	COG1012	belongs to the aldehyde dehydrogenase family
FY142_RS16700	COG0473	3-isopropylmalate dehydrogenase activity
FY142_RS16705	COG1012	belongs to the aldehyde dehydrogenase family
FY142_RS16710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS16745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS16750	COG4172	Belongs to the ABC transporter superfamily
FY142_RS16755	COG1522	sequence-specific DNA binding
FY142_RS16765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS16780	COG0583	DNA-binding transcription factor activity
FY142_RS16790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS16795	COG1126	abc transporter atp-binding protein
FY142_RS16810	COG1473	amidohydrolase
FY142_RS16815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS16820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS16825	COG1959	2 iron, 2 sulfur cluster binding
FY142_RS16835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY142_RS16840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS16870	COG1960	acyl-CoA dehydrogenase activity
FY142_RS16880	COG0747	negative chemotaxis
FY142_RS16895	COG0444	Belongs to the ABC transporter superfamily
FY142_RS16905	COG0667	Aldo Keto reductase
FY142_RS16915	COG0583	DNA-binding transcription factor activity
FY142_RS16920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS16925	COG4166	transmembrane transport
FY142_RS16940	COG0747	negative chemotaxis
FY142_RS16945	COG1473	amidohydrolase
FY142_RS16950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS16965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS16970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS16980	COG1733	regulation of RNA biosynthetic process
FY142_RS16985	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS17120	COG4373	Mu-like prophage FluMu protein gp28
FY142_RS17125	COG4383	Mu-like prophage protein gp29
FY142_RS17130	COG2369	cell adhesion
FY142_RS17265	COG4608	Belongs to the ABC transporter superfamily
FY142_RS17270	COG0444	Belongs to the ABC transporter superfamily
FY142_RS17280	COG0601	transmembrane transport
FY142_RS17290	COG2186	Transcriptional regulator
FY142_RS17305	COG0300	oxidoreductase activity
FY142_RS17315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY142_RS17315	COG3453	Protein conserved in bacteria
FY142_RS17320	COG0640	Transcriptional regulator
FY142_RS17330	COG2391	methyltransferase activity
FY142_RS17335	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY142_RS17345	COG0022	dehydrogenase e1 component
FY142_RS17355	COG1960	acyl-CoA dehydrogenase activity
FY142_RS17360	COG0183	Belongs to the thiolase family
FY142_RS17370	COG1960	acyl-CoA dehydrogenase activity
FY142_RS17375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY142_RS17395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY142_RS17400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY142_RS17405	COG4952	isomerase
FY142_RS17410	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS17410	COG3347	Dehydrogenase
FY142_RS17415	COG1349	DNA-binding transcription factor activity
FY142_RS17425	COG1129	ABC transporter
FY142_RS17430	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS17435	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS17440	COG3254	rhamnose metabolic process
FY142_RS17455	COG2264	protein methyltransferase activity
FY142_RS17460	COG5001	Diguanylate cyclase
FY142_RS17475	COG4335	DNA alkylation repair
FY142_RS17480	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY142_RS17485	COG4208	sulfate ABC transporter
FY142_RS17495	COG4150	thiosulfate binding
FY142_RS17500	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY142_RS17515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY142_RS17525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY142_RS17535	COG1040	competence protein
FY142_RS17540	COG2226	methyltransferase
FY142_RS17555	COG0494	nUDIX hydrolase
FY142_RS17565	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY142_RS17570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY142_RS17575	COG0653	protein targeting
FY142_RS17580	COG0697	spore germination
FY142_RS17645	COG2244	polysaccharide biosynthetic process
FY142_RS17660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY142_RS17670	COG3206	protein involved in exopolysaccharide biosynthesis
FY142_RS17670	COG0489	protein tyrosine kinase activity
FY142_RS17690	COG0438	transferase activity, transferring glycosyl groups
FY142_RS17695	COG0438	transferase activity, transferring glycosyl groups
FY142_RS17710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY142_RS17715	COG2273	Hydrolase Family 16
FY142_RS17715	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY142_RS17730	COG3842	ATPase activity
FY142_RS17735	COG3833	ABC-type maltose transport systems, permease component
FY142_RS17790	COG1396	sequence-specific DNA binding
FY142_RS17800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY142_RS17805	COG1129	ABC transporter
FY142_RS17810	COG4214	carbohydrate transport
FY142_RS17815	COG4213	ABC transporter substrate-binding protein
FY142_RS17830	COG0346	lactoylglutathione lyase activity
FY142_RS17835	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY142_RS17835	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY142_RS17840	COG4770	biotin carboxylase activity
FY142_RS17855	COG0625	glutathione transferase activity
FY142_RS17860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY142_RS17865	COG1396	sequence-specific DNA binding
FY142_RS17865	COG3800	Transcriptional regulator
FY142_RS17875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY142_RS17885	COG0300	oxidoreductase activity
FY142_RS17895	COG2096	Adenosyltransferase
FY142_RS17905	COG2086	electron transfer activity
FY142_RS17915	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY142_RS17925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY142_RS17930	COG0165	Argininosuccinate lyase
FY142_RS17965	COG2884	Cell division ATP-binding protein ftsE
FY142_RS17985	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY142_RS17995	COG0287	Prephenate dehydrogenase
FY142_RS18000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY142_RS18005	COG2226	methyltransferase
FY142_RS18010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY142_RS18030	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY142_RS18035	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY142_RS18075	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY142_RS18080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY142_RS18090	COG4974	Belongs to the 'phage' integrase family
FY142_RS18095	COG0825	malonyl-CoA metabolic process
FY142_RS18100	COG3034	peptidoglycan biosynthetic process
FY142_RS18105	COG0425	Belongs to the sulfur carrier protein TusA family
FY142_RS18105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY142_RS18110	COG0523	cobalamin synthesis protein
FY142_RS18115	COG1686	Belongs to the peptidase S11 family
FY142_RS18120	COG1473	amidohydrolase
FY142_RS18130	COG4953	penicillin-binding protein 1C
FY142_RS18135	COG2373	Large extracellular alpha-helical protein
FY142_RS18140	COG2835	tetraacyldisaccharide 4'-kinase activity
FY142_RS18170	COG0482	sulfurtransferase activity
FY142_RS18185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY142_RS18200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY142_RS18205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY142_RS18210	COG0037	tRNA processing
FY142_RS18220	COG2885	chlorophyll binding
FY142_RS18225	COG0823	Involved in the tonB-independent uptake of proteins
FY142_RS18245	COG0824	Thioesterase
FY142_RS18255	COG0494	nUDIX hydrolase
FY142_RS18270	COG2255	four-way junction helicase activity
FY142_RS18275	COG0632	four-way junction helicase activity
FY142_RS18280	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY142_RS18285	COG0840	transmembrane signaling receptor activity
FY142_RS18290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS18295	COG0217	transcriptional regulatory protein
FY142_RS18310	COG1692	metallophosphoesterase
FY142_RS18320	COG1253	flavin adenine dinucleotide binding
FY142_RS18355	COG3263	regulation of cellular component size
FY142_RS18360	COG0126	phosphoglycerate kinase activity
FY142_RS18365	COG3588	fructose-bisphosphate aldolase
FY142_RS18390	COG0254	rRNA binding
FY142_RS18395	COG1132	(ABC) transporter
FY142_RS18415	COG0483	inositol monophosphate 1-phosphatase activity
FY142_RS18445	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY142_RS18450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY142_RS18455	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY142_RS18460	COG0457	Tetratricopeptide repeat
FY142_RS18465	COG3750	Belongs to the UPF0335 family
FY142_RS18485	COG0469	pyruvate kinase activity
FY142_RS18490	COG3108	Peptidase M15
FY142_RS18495	COG2204	response regulator
FY142_RS18500	COG1164	Oligoendopeptidase f
FY142_RS18505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY142_RS18515	COG5310	Homospermidine synthase
FY142_RS18525	COG0737	Belongs to the 5'-nucleotidase family
FY142_RS18530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY142_RS18535	COG0330	HflC and HflK could
FY142_RS18560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY142_RS18565	COG2951	lytic endotransglycosylase activity
FY142_RS18580	COG2205	protein histidine kinase activity
FY142_RS18595	COG0069	glutamate synthase activity
FY142_RS18595	COG0070	glutamate synthase
FY142_RS18595	COG0067	glutamate synthase
FY142_RS18610	COG2205	protein histidine kinase activity
FY142_RS18615	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY142_RS18620	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY142_RS18630	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY142_RS18640	COG0252	asparaginase activity
FY142_RS18650	COG1027	Aspartate ammonia-lyase
FY142_RS18655	COG2186	Transcriptional regulator
FY142_RS18695	COG4176	ABC-type proline glycine betaine transport system permease component
FY142_RS18700	COG0517	IMP dehydrogenase activity
FY142_RS18700	COG4175	Glycine betaine
FY142_RS18705	COG2986	histidine ammonia-lyase
FY142_RS18710	COG1609	Transcriptional regulator
FY142_RS18730	COG1082	Xylose isomerase domain protein TIM barrel
FY142_RS18735	COG0673	inositol 2-dehydrogenase activity
FY142_RS18740	COG1082	Xylose isomerase domain protein TIM barrel
FY142_RS18765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY142_RS18810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_RS18820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS18825	COG0601	transmembrane transport
FY142_RS18830	COG0747	negative chemotaxis
FY142_RS18840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY142_RS18845	COG1454	alcohol dehydrogenase
FY142_RS18885	COG2307	Protein conserved in bacteria
FY142_RS18885	COG2308	Evidence 4 Homologs of previously reported genes of
FY142_RS18900	COG0488	(ABC) transporter
FY142_RS18905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY142_RS18910	COG2186	Transcriptional regulator
FY142_RS18925	COG1175	transmembrane transport
FY142_RS18930	COG0395	ABC-type sugar transport system, permease component
FY142_RS18940	COG3842	ATPase activity
FY142_RS18965	COG1304	FMN binding
FY142_RS18980	COG1063	alcohol dehydrogenase
FY142_RS18985	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY142_RS18990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS19000	COG0765	amino acid transport
FY142_RS19005	COG0765	amino acid transport
FY142_RS19010	COG4221	oxidoreductase activity
FY142_RS19015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY142_RS19020	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS19025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_RS19040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY142_RS19055	COG0697	spore germination
FY142_RS19060	COG0697	spore germination
FY142_RS19065	COG0511	ligase activity, forming carbon-carbon bonds
FY142_RS19070	COG0439	Biotin carboxylase
FY142_RS19080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY142_RS19085	COG1984	allophanate hydrolase subunit 2
FY142_RS19090	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY142_RS19095	COG3842	ATPase activity
FY142_RS19105	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY142_RS19115	COG0436	Aminotransferase
FY142_RS19130	COG0840	transmembrane signaling receptor activity
FY142_RS19135	COG1070	Carbohydrate kinase
FY142_RS19140	COG1830	Aldolase
FY142_RS19145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY142_RS19150	COG0667	Aldo Keto reductase
FY142_RS19160	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS19165	COG1129	ABC transporter
FY142_RS19170	COG1879	ABC-type sugar transport system periplasmic component
FY142_RS19215	COG0071	Belongs to the small heat shock protein (HSP20) family
FY142_RS19230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY142_RS19245	COG0395	ABC-type sugar transport system, permease component
FY142_RS19260	COG3842	ATPase activity
FY142_RS19275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY142_RS19275	COG1648	precorrin-2 dehydrogenase activity
FY142_RS19280	COG0243	molybdopterin cofactor binding
FY142_RS19290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY142_RS19295	COG1116	anion transmembrane transporter activity
FY142_RS19300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_RS19305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY142_RS19315	COG3707	response regulator
FY142_RS19320	COG1802	Transcriptional regulator
FY142_RS19325	COG1914	H( )-stimulated, divalent metal cation uptake system
FY142_RS19330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY142_RS19335	COG4336	lyase activity
FY142_RS19340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY142_RS19345	COG4770	biotin carboxylase activity
FY142_RS19350	COG0366	Alpha amylase catalytic
FY142_RS19360	COG4771	TonB-dependent receptor
FY142_RS19365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY142_RS19385	COG1414	Transcriptional regulator
FY142_RS19390	COG1475	DNA binding
FY142_RS19395	COG1192	Involved in chromosome partitioning
FY142_RS19425	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY142_RS19435	COG2986	histidine ammonia-lyase
FY142_RS19440	COG1228	amidohydrolase
FY142_RS19445	COG0402	S-adenosylhomocysteine deaminase activity
FY142_RS19485	COG4172	Belongs to the ABC transporter superfamily
FY142_RS19490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS19495	COG0601	transmembrane transport
FY142_RS19500	COG4166	transmembrane transport
FY142_RS19505	COG0395	ABC-type sugar transport system, permease component
FY142_RS19525	COG1566	PFAM secretion protein HlyD family protein
FY142_RS19540	COG2207	Transcriptional regulator
FY142_RS19545	COG1309	transcriptional regulator
FY142_RS19550	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS19575	COG1846	Transcriptional regulator
FY142_RS19580	COG0583	DNA-binding transcription factor activity
FY142_RS19585	COG2828	Protein conserved in bacteria
FY142_RS19600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_RS19615	COG0840	transmembrane signaling receptor activity
FY142_RS19635	COG1215	transferase activity, transferring glycosyl groups
FY142_RS19665	COG0583	DNA-binding transcription factor activity
FY142_RS19670	COG0346	lactoylglutathione lyase activity
FY142_RS19685	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY142_RS19705	COG0583	DNA-binding transcription factor activity
FY142_RS19710	COG0477	Major facilitator Superfamily
FY142_RS19720	COG2205	protein histidine kinase activity
FY142_RS19725	COG0745	RESPONSE REGULATOR receiver
FY142_RS19730	COG0671	phosphoesterase, PA-phosphatase related
FY142_RS19780	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY142_RS19785	COG0156	8-amino-7-oxononanoate synthase activity
FY142_RS19790	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY142_RS19795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY142_RS19800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY142_RS19815	COG0010	Belongs to the arginase family
FY142_RS19825	COG0697	spore germination
FY142_RS19830	COG0673	inositol 2-dehydrogenase activity
FY142_RS19850	COG0477	Major facilitator Superfamily
FY142_RS19865	COG2194	sulfuric ester hydrolase activity
FY142_RS19875	COG0583	DNA-binding transcription factor activity
FY142_RS19880	COG4774	siderophore transport
FY142_RS19895	COG1120	ATPase activity
FY142_RS19905	COG3474	cytochrome
FY142_RS19910	COG2137	regulation of response to DNA damage stimulus
FY142_RS19915	COG3386	PFAM SMP-30 Gluconolaconase
FY142_RS19925	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS19930	COG1129	ABC transporter
FY142_RS19935	COG1879	ABC-type sugar transport system periplasmic component
FY142_RS19940	COG4585	Histidine kinase
FY142_RS19945	COG2197	response regulator
FY142_RS19955	COG2133	pyrroloquinoline quinone binding
FY142_RS19965	COG0500	methyltransferase
FY142_RS19970	COG0564	pseudouridine synthase activity
FY142_RS19985	COG4175	Glycine betaine
FY142_RS19985	COG3448	diguanylate cyclase activity
FY142_RS19990	COG4176	ABC-type proline glycine betaine transport system permease component
FY142_RS20005	COG0784	Response regulator, receiver
FY142_RS20005	COG4191	Histidine kinase
FY142_RS20010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY142_RS20015	COG0489	protein tyrosine kinase activity
FY142_RS20015	COG3206	protein involved in exopolysaccharide biosynthesis
FY142_RS20020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY142_RS20025	COG1215	transferase activity, transferring glycosyl groups
FY142_RS20030	COG1215	transferase activity, transferring glycosyl groups
FY142_RS20035	COG1215	transferase activity, transferring glycosyl groups
FY142_RS20040	COG0438	transferase activity, transferring glycosyl groups
FY142_RS20045	COG2273	Hydrolase Family 16
FY142_RS20050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY142_RS20055	COG2244	polysaccharide biosynthetic process
FY142_RS20060	COG0463	Glycosyl transferase, family 2
FY142_RS20065	COG2327	Polysaccharide pyruvyl transferase
FY142_RS20070	COG1215	transferase activity, transferring glycosyl groups
FY142_RS20090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY142_RS20095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS20110	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY142_RS20110	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY142_RS20140	COG1523	belongs to the glycosyl hydrolase 13 family
FY142_RS20145	COG0033	Phosphoglucomutase
FY142_RS20150	COG0297	glycogen (starch) synthase activity
FY142_RS20155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY142_RS20160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY142_RS20165	COG0058	SHG alpha-glucan phosphorylase activity
FY142_RS20180	COG1794	racemase activity, acting on amino acids and derivatives
FY142_RS20185	COG1522	sequence-specific DNA binding
FY142_RS20195	COG2084	Dehydrogenase
FY142_RS20200	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS20205	COG1063	alcohol dehydrogenase
FY142_RS20215	COG4988	ABC transporter
FY142_RS20220	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY142_RS20230	COG1294	oxidase, subunit
FY142_RS20260	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY142_RS20265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY142_RS20295	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY142_RS20300	COG0539	negative regulation of cytoplasmic translation
FY142_RS20330	COG4221	oxidoreductase activity
FY142_RS20340	COG0747	negative chemotaxis
FY142_RS20345	COG0601	transmembrane transport
FY142_RS20350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS20355	COG0444	Belongs to the ABC transporter superfamily
FY142_RS20360	COG4608	Belongs to the ABC transporter superfamily
FY142_RS20365	COG0246	Mannitol dehydrogenase
FY142_RS20380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS20425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY142_RS20430	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS20445	COG4993	Dehydrogenase
FY142_RS20450	COG3685	Protein conserved in bacteria
FY142_RS20480	COG0693	protein deglycase activity
FY142_RS20500	COG0189	ligase activity
FY142_RS20505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_RS20510	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY142_RS20525	COG0435	Glutathione S-transferase
FY142_RS20530	COG0583	DNA-binding transcription factor activity
FY142_RS20535	COG1012	belongs to the aldehyde dehydrogenase family
FY142_RS20540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY142_RS20545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_RS20550	COG1116	anion transmembrane transporter activity
FY142_RS20560	COG1522	sequence-specific DNA binding
FY142_RS20575	COG0784	Response regulator, receiver
FY142_RS20595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY142_RS20610	COG0019	diaminopimelate decarboxylase activity
FY142_RS20625	COG0527	aspartate kinase activity
FY142_RS20635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY142_RS20640	COG2890	protein-(glutamine-N5) methyltransferase activity
FY142_RS20650	COG0542	response to heat
FY142_RS20655	COG0739	heme binding
FY142_RS20655	COG1196	nuclear chromosome segregation
FY142_RS20655	COG0741	lytic transglycosylase activity
FY142_RS20695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY142_RS20705	COG1280	lysine exporter protein (LysE YggA)
FY142_RS20720	COG1309	transcriptional regulator
FY142_RS20725	COG4221	oxidoreductase activity
FY142_RS20730	COG1902	pentaerythritol trinitrate reductase activity
FY142_RS20735	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS20775	COG1278	Cold shock
FY142_RS20795	COG0753	catalase activity
FY142_RS20820	COG3920	Histidine kinase
FY142_RS20825	COG1280	lysine exporter protein (LysE YggA)
FY142_RS20845	COG0583	DNA-binding transcription factor activity
FY142_RS20880	COG0583	DNA-binding transcription factor activity
FY142_RS20890	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS20895	COG1846	Transcriptional regulator
FY142_RS20915	COG2186	Transcriptional regulator
FY142_RS20925	COG1126	abc transporter atp-binding protein
FY142_RS20935	COG0765	amino acid transport
FY142_RS20940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS20955	COG0436	Aminotransferase
FY142_RS20960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_RS20990	COG0405	Gamma-glutamyltransferase
FY142_RS21000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY142_RS21005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS21010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS21020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS21025	COG0747	negative chemotaxis
FY142_RS21030	COG0747	negative chemotaxis
FY142_RS21040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS21050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS21060	COG1129	ABC transporter
FY142_RS21065	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS21070	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS21095	COG0667	Aldo Keto reductase
FY142_RS21110	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS21115	COG1129	ABC transporter
FY142_RS21120	COG4213	ABC transporter substrate-binding protein
FY142_RS21140	COG4608	Belongs to the ABC transporter superfamily
FY142_RS21145	COG0444	Belongs to the ABC transporter superfamily
FY142_RS21150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS21155	COG0601	transmembrane transport
FY142_RS21160	COG0747	negative chemotaxis
FY142_RS21185	COG0765	amino acid transport
FY142_RS21190	COG4597	amino acid ABC transporter
FY142_RS21195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS21210	COG3177	Filamentation induced by cAMP protein fic
FY142_RS21235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS21265	COG3209	COG3209 Rhs family protein
FY142_RS21285	COG0745	RESPONSE REGULATOR receiver
FY142_RS21295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_RS21300	COG0577	efflux transmembrane transporter activity
FY142_RS21300	COG1136	(ABC) transporter
FY142_RS21310	COG1733	regulation of RNA biosynthetic process
FY142_RS21345	COG0534	Mate efflux family protein
FY142_RS21360	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY142_RS21365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY142_RS21375	COG1566	PFAM secretion protein HlyD family protein
FY142_RS21385	COG0625	glutathione transferase activity
FY142_RS21390	COG4221	oxidoreductase activity
FY142_RS21400	COG2376	Dihydroxyacetone kinase
FY142_RS21405	COG1522	sequence-specific DNA binding
FY142_RS21425	COG0431	NADPH-dependent FMN reductase
FY142_RS21435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS21445	COG4172	Belongs to the ABC transporter superfamily
FY142_RS21450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS21470	COG0277	FAD linked oxidase domain protein
FY142_RS21490	COG0778	Nitroreductase
FY142_RS21520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY142_RS21545	COG2318	DinB family
FY142_RS21550	COG0583	DNA-binding transcription factor activity
FY142_RS21565	COG1335	isochorismatase
FY142_RS21590	COG3842	ATPase activity
FY142_RS21595	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_RS21600	COG1177	transmembrane transport
FY142_RS21605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY142_RS21615	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY142_RS21630	COG1120	ATPase activity
FY142_RS21635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_RS21640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_RS21645	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY142_RS21650	COG1629	transport
FY142_RS21650	COG4774	siderophore transport
FY142_RS21655	COG4702	Belongs to the UPF0303 family
FY142_RS21675	COG1024	Enoyl-CoA hydratase
FY142_RS21680	COG1012	belongs to the aldehyde dehydrogenase family
FY142_RS21685	COG1653	transport
FY142_RS21690	COG1175	transmembrane transport
FY142_RS21695	COG0395	ABC-type sugar transport system, permease component
FY142_RS21700	COG3842	ATPase activity
FY142_RS21730	COG3474	cytochrome
FY142_RS21735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY142_RS21740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY142_RS21745	COG1845	cytochrome c oxidase, subunit III
FY142_RS21770	COG0577	efflux transmembrane transporter activity
FY142_RS21770	COG1136	(ABC) transporter
FY142_RS21830	COG3842	ATPase activity
FY142_RS21840	COG1177	transmembrane transport
FY142_RS21845	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_RS21860	COG1940	carbohydrate kinase activity
FY142_RS21880	COG1069	ribulokinase activity
FY142_RS21885	COG1349	DNA-binding transcription factor activity
FY142_RS21890	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS21915	COG0395	ABC-type sugar transport system, permease component
FY142_RS21925	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS21940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY142_RS21950	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY142_RS21960	COG0477	Major facilitator Superfamily
FY142_RS22010	COG1733	regulation of RNA biosynthetic process
FY142_RS22045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY142_RS22050	COG3938	Belongs to the proline racemase family
FY142_RS22055	COG4176	ABC-type proline glycine betaine transport system permease component
FY142_RS22065	COG4175	Glycine betaine
FY142_RS22065	COG3448	diguanylate cyclase activity
FY142_RS22075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS22080	COG1012	belongs to the aldehyde dehydrogenase family
FY142_RS22085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_RS22095	COG0047	phosphoribosylformylglycinamidine synthase activity
FY142_RS22100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS22110	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY142_RS22110	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY142_RS22120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY142_RS22145	COG1309	transcriptional regulator
FY142_RS22160	COG1136	(ABC) transporter
FY142_RS22175	COG1063	alcohol dehydrogenase
FY142_RS22185	COG1879	ABC-type sugar transport system periplasmic component
FY142_RS22195	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS22215	COG0477	Major facilitator Superfamily
FY142_RS22345	COG3300	MHYT domain
FY142_RS22345	COG5001	Diguanylate cyclase
FY142_RS22370	COG1253	flavin adenine dinucleotide binding
FY142_RS22385	COG3842	ATPase activity
FY142_RS22390	COG0395	ABC-type sugar transport system, permease component
FY142_RS22395	COG1175	transmembrane transport
FY142_RS22400	COG1653	transport
FY142_RS22410	COG0673	inositol 2-dehydrogenase activity
FY142_RS22415	COG1609	Transcriptional regulator
FY142_RS22430	COG0583	DNA-binding transcription factor activity
FY142_RS22440	COG1879	ABC-type sugar transport system periplasmic component
FY142_RS22445	COG1129	ABC transporter
FY142_RS22450	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS22455	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS22460	COG1609	Transcriptional regulator
FY142_RS22470	COG0673	inositol 2-dehydrogenase activity
FY142_RS22530	COG0714	Associated with various cellular activities
FY142_RS22535	COG3256	nitric oxide reductase
FY142_RS22570	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY142_RS22575	COG3189	MarR family transcriptional regulator
FY142_RS22585	COG0826	peptidase U32
FY142_RS22620	COG4459	periplasmic nitrate reductase
FY142_RS22635	COG0243	molybdopterin cofactor binding
FY142_RS22645	COG3005	denitrification pathway
FY142_RS22660	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS22665	COG3433	isochorismatase activity
FY142_RS22665	COG1535	isochorismatase
FY142_RS22670	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY142_RS22675	COG1169	isochorismate synthase
FY142_RS22685	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY142_RS22685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY142_RS22690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY142_RS22700	COG2375	cellular response to nickel ion
FY142_RS22710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_RS22715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_RS22725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS22735	COG4774	siderophore transport
FY142_RS22735	COG1629	transport
FY142_RS22740	COG1960	acyl-CoA dehydrogenase activity
FY142_RS22745	COG0583	DNA-binding transcription factor activity
FY142_RS22750	COG1609	Transcriptional regulator
FY142_RS22760	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_RS22770	COG3842	ATPase activity
FY142_RS22780	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY142_RS22785	COG0583	DNA-binding transcription factor activity
FY142_RS22790	COG2814	Major facilitator Superfamily
FY142_RS22795	COG1473	amidohydrolase
FY142_RS22810	COG0747	negative chemotaxis
FY142_RS22815	COG0601	transmembrane transport
FY142_RS22820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS22825	COG0444	Belongs to the ABC transporter superfamily
FY142_RS22830	COG4608	Belongs to the ABC transporter superfamily
FY142_RS22835	COG0583	DNA-binding transcription factor activity
FY142_RS22840	COG0747	negative chemotaxis
FY142_RS22850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS22855	COG0154	amidase activity
FY142_RS22860	COG0693	protein deglycase activity
FY142_RS22870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS22875	COG0601	transmembrane transport
FY142_RS22885	COG1473	amidohydrolase
FY142_RS22890	COG4172	Belongs to the ABC transporter superfamily
FY142_RS22895	COG2390	Transcriptional regulator
FY142_RS22905	COG1175	transmembrane transport
FY142_RS22910	COG0395	ABC-type sugar transport system, permease component
FY142_RS22960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY142_RS22980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY142_RS22985	COG1414	Transcriptional regulator
FY142_RS22990	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS23000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY142_RS23005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY142_RS23010	COG1121	(ABC) transporter
FY142_RS23015	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY142_RS23025	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY142_RS23030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY142_RS23035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY142_RS23040	COG3273	potassium ion transport
FY142_RS23040	COG0471	metal ion transport
FY142_RS23045	COG1253	flavin adenine dinucleotide binding
FY142_RS23050	COG1309	transcriptional regulator
FY142_RS23070	COG1609	Transcriptional regulator
FY142_RS23075	COG1070	Carbohydrate kinase
FY142_RS23080	COG2115	Belongs to the xylose isomerase family
FY142_RS23090	COG0778	Nitroreductase
FY142_RS23095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY142_RS23100	COG2011	ABC-type metal ion transport system permease component
FY142_RS23110	COG5001	Diguanylate cyclase
FY142_RS23110	COG3300	MHYT domain
FY142_RS23115	COG1054	Belongs to the UPF0176 family
FY142_RS23125	COG2954	triphosphatase activity
FY142_RS23130	COG0800	Aldolase
FY142_RS23150	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY142_RS23190	COG0523	cobalamin synthesis protein
FY142_RS23200	COG1846	Transcriptional regulator
FY142_RS23205	COG1609	Transcriptional regulator
FY142_RS23210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY142_RS23220	COG3718	enzyme involved in inositol metabolism
FY142_RS23230	COG3962	Belongs to the TPP enzyme family
FY142_RS23235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_RS23250	COG0411	ABC transporter
FY142_RS23265	COG0683	leucine binding
FY142_RS23280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS23290	COG0747	negative chemotaxis
FY142_RS23295	COG4172	Belongs to the ABC transporter superfamily
FY142_RS23320	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY142_RS23325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY142_RS23330	COG1126	abc transporter atp-binding protein
FY142_RS23335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS23340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS23345	COG0765	amino acid transport
FY142_RS23350	COG0765	amino acid transport
FY142_RS23355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY142_RS23360	COG3485	protocatechuate 3,4-dioxygenase
FY142_RS23365	COG3485	protocatechuate 3,4-dioxygenase
FY142_RS23370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY142_RS23380	COG0583	DNA-binding transcription factor activity
FY142_RS23395	COG1414	Transcriptional regulator
FY142_RS23405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY142_RS23410	COG0183	Belongs to the thiolase family
FY142_RS23415	COG1609	Transcriptional regulator
FY142_RS23430	COG1082	Xylose isomerase domain protein TIM barrel
FY142_RS23435	COG0673	inositol 2-dehydrogenase activity
FY142_RS23445	COG1609	Transcriptional regulator
FY142_RS23450	COG0395	ABC-type sugar transport system, permease component
FY142_RS23455	COG1175	transmembrane transport
FY142_RS23460	COG3842	ATPase activity
FY142_RS23470	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY142_RS23490	COG2814	Major facilitator Superfamily
FY142_RS23495	COG4774	siderophore transport
FY142_RS23500	COG3712	iron ion homeostasis
FY142_RS23510	COG1940	carbohydrate kinase activity
FY142_RS23515	COG0584	glycerophosphoryl diester phosphodiesterase
FY142_RS23520	COG0300	oxidoreductase activity
FY142_RS23535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY142_RS23555	COG0667	Aldo Keto reductase
FY142_RS23560	COG0583	DNA-binding transcription factor activity
FY142_RS23570	COG1132	(ABC) transporter
FY142_RS23585	COG1216	Glycosyl transferase, family 2
FY142_RS23585	COG1442	glycosyl transferase family 8
FY142_RS23590	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY142_RS23600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY142_RS23620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY142_RS23625	COG3754	Rhamnan synthesis protein F
FY142_RS23640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY142_RS23645	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY142_RS23650	COG1088	dTDP-glucose 4,6-dehydratase activity
FY142_RS23655	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY142_RS23660	COG0210	DNA helicase
FY142_RS23670	COG1609	Transcriptional regulator
FY142_RS23675	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY142_RS23675	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY142_RS23690	COG0395	ABC-type sugar transport system, permease component
FY142_RS23695	COG3842	ATPase activity
FY142_RS23705	COG0444	Belongs to the ABC transporter superfamily
FY142_RS23710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS23715	COG0601	transmembrane transport
FY142_RS23720	COG2186	Transcriptional regulator
FY142_RS23740	COG3300	MHYT domain
FY142_RS23740	COG5001	Diguanylate cyclase
FY142_RS23745	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS23755	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY142_RS23765	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY142_RS23770	COG0306	phosphate transporter
FY142_RS23775	COG1392	Phosphate transport regulator
FY142_RS23790	COG1566	PFAM secretion protein HlyD family protein
FY142_RS23795	COG0745	RESPONSE REGULATOR receiver
FY142_RS23800	COG2205	protein histidine kinase activity
FY142_RS23815	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY142_RS23830	COG4774	siderophore transport
FY142_RS23840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_RS23845	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_RS23850	COG1120	ATPase activity
FY142_RS23855	COG0583	DNA-binding transcription factor activity
FY142_RS23865	COG3119	arylsulfatase activity
FY142_RS23870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_RS23875	COG3842	ATPase activity
FY142_RS23880	COG0165	Argininosuccinate lyase
FY142_RS23885	COG0395	ABC-type sugar transport system, permease component
FY142_RS23890	COG1175	transmembrane transport
FY142_RS23895	COG2182	Extracellular solute-binding protein
FY142_RS23900	COG1940	carbohydrate kinase activity
FY142_RS23925	COG1486	melibiose metabolic process
FY142_RS23930	COG0747	negative chemotaxis
FY142_RS23935	COG0601	transmembrane transport
FY142_RS23940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS23945	COG4172	Belongs to the ABC transporter superfamily
FY142_RS23950	COG1486	melibiose metabolic process
FY142_RS23955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_RS23960	COG0842	Transport permease protein
FY142_RS23960	COG1129	ABC transporter
FY142_RS23965	COG0842	Transport permease protein
FY142_RS23980	COG0784	Response regulator, receiver
FY142_RS23985	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY142_RS23995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_RS24000	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY142_RS24015	COG0765	amino acid transport
FY142_RS24025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_RS24035	COG3938	Belongs to the proline racemase family
FY142_RS24050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS24055	COG0765	amino acid transport
FY142_RS24060	COG0765	amino acid transport
FY142_RS24070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY142_RS24085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY142_RS24105	COG3383	formate dehydrogenase (NAD+) activity
FY142_RS24115	COG2223	nitrite transmembrane transporter activity
FY142_RS24120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_RS24130	COG2186	Transcriptional regulator
FY142_RS24135	COG0747	negative chemotaxis
FY142_RS24140	COG0601	transmembrane transport
FY142_RS24145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS24150	COG4172	Belongs to the ABC transporter superfamily
FY142_RS24155	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_RS24165	COG2186	Transcriptional regulator
FY142_RS24170	COG0747	negative chemotaxis
FY142_RS24175	COG0601	transmembrane transport
FY142_RS24180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS24185	COG0405	Gamma-glutamyltransferase
FY142_RS24195	COG0483	inositol monophosphate 1-phosphatase activity
FY142_RS24205	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY142_RS24210	COG0395	ABC-type sugar transport system, permease component
FY142_RS24230	COG3237	CsbD-like
FY142_RS24240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY142_RS24245	COG3181	Tripartite tricarboxylate transporter family receptor
FY142_RS24250	COG5265	(ABC) transporter
FY142_RS24255	COG0488	(ABC) transporter
FY142_RS24280	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY142_RS24285	COG0110	maltose O-acetyltransferase activity
FY142_RS24295	COG1063	alcohol dehydrogenase
FY142_RS24300	COG3284	Transcriptional regulator
FY142_RS24320	COG1129	ABC transporter
FY142_RS24325	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS24330	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS24340	COG0572	uridine kinase
FY142_RS24345	COG1082	Xylose isomerase domain protein TIM barrel
FY142_RS24370	COG4178	(ABC) transporter
FY142_RS24405	COG0640	Transcriptional regulator
FY142_RS24420	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY142_RS24425	COG1192	Involved in chromosome partitioning
FY142_RS24430	COG1475	DNA binding
FY142_RS24435	COG0640	Transcriptional regulator
FY142_RS24450	COG1126	abc transporter atp-binding protein
FY142_RS24460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_RS24465	COG1609	Transcriptional regulator
FY142_RS24500	COG3239	Fatty acid desaturase
FY142_RS24510	COG1278	Cold shock
FY142_RS24585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY142_RS24585	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY142_RS24625	COG4191	Histidine kinase
FY142_RS24640	COG0640	Transcriptional regulator
FY142_RS24670	COG4977	sequence-specific DNA binding
FY142_RS24675	COG2211	Major facilitator Superfamily
FY142_RS24680	COG2807	transmembrane transport
FY142_RS24685	COG1846	Transcriptional regulator
FY142_RS24700	COG2814	Major facilitator Superfamily
FY142_RS24730	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY142_RS24745	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY142_RS24750	COG0583	DNA-binding transcription factor activity
FY142_RS24765	COG0071	Belongs to the small heat shock protein (HSP20) family
FY142_RS24815	COG3838	Conjugal transfer protein Trbc
FY142_RS24820	COG3702	type iv secretory pathway
FY142_RS24825	COG3451	type IV secretory pathway VirB4
FY142_RS24840	COG3704	protein secretion by the type IV secretion system
FY142_RS24850	COG3736	Type IV secretory pathway, component VirB8
FY142_RS24855	COG3504	Conjugal transfer protein
FY142_RS24860	COG2948	multi-organism process
FY142_RS24865	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY142_RS24970	COG3831	ATPase activity
FY142_RS24985	COG3505	Type IV secretory pathway VirD4
FY142_RS25005	COG0583	DNA-binding transcription factor activity
FY142_RS25050	COG0745	RESPONSE REGULATOR receiver
FY142_RS25090	COG3842	ATPase activity
FY142_RS25095	COG4208	sulfate ABC transporter
FY142_RS25100	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_RS25120	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY142_RS25125	COG1942	4-Oxalocrotonate Tautomerase
FY142_RS25135	COG3971	2-oxopent-4-enoate hydratase activity
FY142_RS25145	COG1414	Transcriptional regulator
FY142_RS25155	COG1137	ATPase activity
FY142_RS25170	COG4177	L-phenylalanine transmembrane transporter activity
FY142_RS25190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY142_RS25195	COG1175	transmembrane transport
FY142_RS25200	COG0395	ABC-type sugar transport system, permease component
FY142_RS25210	COG0366	Alpha amylase catalytic
FY142_RS25215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY142_RS25220	COG1082	Xylose isomerase domain protein TIM barrel
FY142_RS25225	COG3842	ATPase activity
FY142_RS25235	COG1940	carbohydrate kinase activity
FY142_RS25240	COG0395	ABC-type sugar transport system, permease component
FY142_RS25250	COG2182	Extracellular solute-binding protein
FY142_RS25255	COG0673	inositol 2-dehydrogenase activity
FY142_RS25285	COG1126	abc transporter atp-binding protein
FY142_RS25290	COG0765	amino acid transport
FY142_RS25295	COG0765	amino acid transport
FY142_RS25305	COG4608	Belongs to the ABC transporter superfamily
FY142_RS25315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS25330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY142_RS25335	COG0583	DNA-binding transcription factor activity
FY142_RS25340	COG2423	ornithine cyclodeaminase activity
FY142_RS25350	COG1957	nucleoside hydrolase
FY142_RS25360	COG1309	transcriptional regulator
FY142_RS25370	COG1335	isochorismatase
FY142_RS25375	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS25380	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS25425	COG0583	DNA-binding transcription factor activity
FY142_RS25430	COG1902	pentaerythritol trinitrate reductase activity
FY142_RS25435	COG0583	DNA-binding transcription factor activity
FY142_RS25440	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS25450	COG1335	isochorismatase
FY142_RS25455	COG0583	DNA-binding transcription factor activity
FY142_RS25465	COG1695	Transcriptional regulator
FY142_RS25550	COG2207	Transcriptional regulator
FY142_RS25610	COG1802	Transcriptional regulator
FY142_RS25615	COG3485	protocatechuate 3,4-dioxygenase
FY142_RS25620	COG3971	2-oxopent-4-enoate hydratase activity
FY142_RS25635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY142_RS25640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY142_RS25655	COG1063	alcohol dehydrogenase
FY142_RS25665	COG1960	acyl-CoA dehydrogenase activity
FY142_RS25670	COG1024	Enoyl-CoA hydratase
FY142_RS25680	COG1012	belongs to the aldehyde dehydrogenase family
FY142_RS25685	COG0477	Major facilitator Superfamily
FY142_RS25700	COG3706	GGDEF domain
FY142_RS25720	COG1846	Transcriptional regulator
FY142_RS25760	COG1012	belongs to the aldehyde dehydrogenase family
FY142_RS25770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY142_RS25780	COG3386	PFAM SMP-30 Gluconolaconase
FY142_RS25785	COG3622	Belongs to the hyi family
FY142_RS25790	COG2084	Dehydrogenase
FY142_RS25815	COG1940	carbohydrate kinase activity
FY142_RS25820	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_RS25830	COG1129	ABC transporter
FY142_RS25850	COG0583	DNA-binding transcription factor activity
FY142_RS25855	COG2271	Major facilitator Superfamily
FY142_RS25865	COG2272	Belongs to the type-B carboxylesterase lipase family
FY142_RS25885	COG1129	ABC transporter
FY142_RS25910	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY142_RS25920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY142_RS25955	COG0583	DNA-binding transcription factor activity
FY142_RS25960	COG1414	Transcriptional regulator
FY142_RS25970	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_RS25980	COG3842	ATPase activity
FY142_RS25985	COG1175	transmembrane transport
FY142_RS25990	COG0395	ABC-type sugar transport system, permease component
FY142_RS26000	COG0477	Major facilitator Superfamily
FY142_RS26035	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY142_RS26050	COG0583	DNA-binding transcription factor activity
FY142_RS26055	COG0747	negative chemotaxis
FY142_RS26065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS26080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_RS26090	COG4215	(ABC) transporter
FY142_RS26145	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY142_RS26150	COG0251	oxidation-reduction process
FY142_RS26185	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS26190	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_RS26195	COG1335	isochorismatase
FY142_RS26205	COG1309	transcriptional regulator
FY142_RS26210	COG4604	ABC transporter, ATP-binding protein
FY142_RS26215	COG4605	iron ion homeostasis
FY142_RS26220	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_RS26230	COG2132	Multicopper oxidase
FY142_RS26235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY142_RS26285	COG1695	Transcriptional regulator
FY142_RS26320	COG2132	Multicopper oxidase
FY142_RS26355	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY142_RS26375	COG1192	Involved in chromosome partitioning
FY142_RS26380	COG1475	DNA binding
FY142_RS26385	COG0640	Transcriptional regulator
FY142_RS26390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY142_RS26420	COG2211	Major facilitator Superfamily
FY142_RS26465	COG4974	Belongs to the 'phage' integrase family
FY142_RS26470	COG1051	belongs to the nudix hydrolase family
FY142_RS26515	COG1475	DNA binding
FY142_RS26540	COG2824	Alkylphosphonate utilization operon protein PhnA
FY142_RS26560	COG1280	lysine exporter protein (LysE YggA)
FY142_RS26625	COG5489	Protein of unknown function (DUF736)
FY142_RS26715	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY142_RS26730	COG0747	negative chemotaxis
FY142_RS26750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS26755	COG0584	glycerophosphoryl diester phosphodiesterase
FY142_RS26760	COG0483	inositol monophosphate 1-phosphatase activity
FY142_RS26825	COG3161	chorismate lyase activity
FY142_RS27065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_RS27095	COG0583	DNA-binding transcription factor activity
FY142_RS27100	COG0747	negative chemotaxis
FY142_RS27115	COG0252	asparaginase activity
FY142_RS27120	COG0583	DNA-binding transcription factor activity
FY142_RS27140	COG3842	ATPase activity
FY142_RS27165	COG3701	Conjugal transfer protein
FY142_RS27170	COG3846	protein secretion by the type IV secretion system
FY142_RS27180	COG5314	conjugation
FY142_RS27185	COG3451	type IV secretory pathway VirB4
FY142_RS27200	COG4962	Type ii secretion system protein e
