locus-tag	class	description
FY144_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY144_RS00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY144_RS00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY144_RS00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY144_RS00025	COG1420	regulation of RNA biosynthetic process
FY144_RS00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY144_RS00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY144_RS00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY144_RS00050	COG1137	ATPase activity
FY144_RS00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY144_RS00065	COG0616	signal peptide processing
FY144_RS00070	COG0776	regulation of translation
FY144_RS00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY144_RS00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY144_RS00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY144_RS00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY144_RS00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY144_RS00115	COG0728	peptidoglycan biosynthetic process
FY144_RS00125	COG0180	Tryptophanyl-tRNA synthetase
FY144_RS00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY144_RS00140	COG1214	PFAM Peptidase M22, glycoprotease
FY144_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY144_RS00165	COG1702	phosphate starvation-inducible protein PhoH
FY144_RS00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY144_RS00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY144_RS00185	COG1396	sequence-specific DNA binding
FY144_RS00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY144_RS00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY144_RS00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_RS00210	COG0242	peptide deformylase activity
FY144_RS00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY144_RS00220	COG0101	tRNA pseudouridine synthase activity
FY144_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY144_RS00235	COG2171	N-acyltransferase activity
FY144_RS00245	COG0840	transmembrane signaling receptor activity
FY144_RS00250	COG1957	nucleoside hydrolase
FY144_RS00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY144_RS00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY144_RS00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY144_RS00295	COG0706	membrane insertase activity
FY144_RS00300	COG0594	ribonuclease P activity
FY144_RS00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY144_RS00310	COG0840	transmembrane signaling receptor activity
FY144_RS00325	COG2226	methyltransferase
FY144_RS00330	COG3842	ATPase activity
FY144_RS00335	COG1175	transmembrane transport
FY144_RS00340	COG0395	ABC-type sugar transport system, permease component
FY144_RS00355	COG0427	acetyl-CoA hydrolase
FY144_RS00365	COG3938	Belongs to the proline racemase family
FY144_RS00370	COG0418	dihydroorotase activity
FY144_RS00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY144_RS00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY144_RS00400	COG0166	Belongs to the GPI family
FY144_RS00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY144_RS00410	COG3842	ATPase activity
FY144_RS00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY144_RS00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY144_RS00425	COG4774	siderophore transport
FY144_RS00465	COG2815	serine threonine protein kinase
FY144_RS00465	COG0515	serine threonine protein kinase
FY144_RS00520	COG2326	polyphosphate kinase activity
FY144_RS00525	COG5002	protein histidine kinase activity
FY144_RS00530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY144_RS00535	COG0573	inorganic phosphate transmembrane transporter activity
FY144_RS00545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY144_RS00550	COG0704	Plays a role in the regulation of phosphate uptake
FY144_RS00555	COG0745	RESPONSE REGULATOR receiver
FY144_RS00565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY144_RS00570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY144_RS00580	COG2967	ApaG domain
FY144_RS00590	COG0717	Belongs to the dCTP deaminase family
FY144_RS00600	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY144_RS00605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY144_RS00655	COG0167	dihydroorotate dehydrogenase activity
FY144_RS00670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY144_RS00690	COG1959	2 iron, 2 sulfur cluster binding
FY144_RS00695	COG1201	RNA secondary structure unwinding
FY144_RS00725	COG1960	acyl-CoA dehydrogenase activity
FY144_RS00730	COG0183	Belongs to the thiolase family
FY144_RS00735	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY144_RS00735	COG1024	Enoyl-CoA hydratase
FY144_RS00760	COG1320	monovalent cation:proton antiporter activity
FY144_RS00765	COG2212	antiporter activity
FY144_RS00770	COG1863	multisubunit Na H antiporter MnhE subunit
FY144_RS00775	COG0651	ATP synthesis coupled electron transport
FY144_RS00780	COG1006	Multisubunit Na H antiporter MnhC subunit
FY144_RS00785	COG2111	Na H antiporter
FY144_RS00785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY144_RS00795	COG0840	transmembrane signaling receptor activity
FY144_RS00805	COG0745	RESPONSE REGULATOR receiver
FY144_RS00810	COG0643	Histidine kinase
FY144_RS00810	COG2198	Histidine kinase
FY144_RS00815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY144_RS00820	COG2201	protein-glutamate methylesterase activity
FY144_RS00825	COG0745	RESPONSE REGULATOR receiver
FY144_RS00830	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY144_RS00840	COG1766	The M ring may be actively involved in energy transduction
FY144_RS00845	COG2771	luxR family
FY144_RS00855	COG0840	transmembrane signaling receptor activity
FY144_RS00855	COG2972	Histidine kinase
FY144_RS00860	COG0784	Response regulator, receiver
FY144_RS00860	COG2198	Histidine kinase
FY144_RS00860	COG2205	protein histidine kinase activity
FY144_RS00865	COG1970	mechanosensitive ion channel activity
FY144_RS00870	COG0436	Aminotransferase
FY144_RS00885	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY144_RS00890	COG0424	maF-like protein
FY144_RS00895	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY144_RS00905	COG5328	Belongs to the UPF0262 family
FY144_RS00910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY144_RS00920	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY144_RS00940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY144_RS00950	COG1338	Plays a role in the flagellum-specific transport system
FY144_RS00960	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY144_RS00970	COG1706	bacterial-type flagellum-dependent cell motility
FY144_RS00975	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY144_RS00980	COG4786	Flagellar basal body rod
FY144_RS00985	COG1677	Flagellar hook-basal body complex protein FliE
FY144_RS00990	COG1558	bacterial-type flagellum-dependent cell motility
FY144_RS00995	COG1815	bacterial-type flagellum-dependent cell motility
FY144_RS01005	COG1157	protein secretion by the type III secretion system
FY144_RS01010	COG4786	Flagellar basal body rod
FY144_RS01020	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY144_RS01025	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY144_RS01030	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY144_RS01035	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY144_RS01040	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY144_RS01060	COG1360	Flagellar Motor Protein
FY144_RS01105	COG5443	negative regulation of bacterial-type flagellum assembly
FY144_RS01110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY144_RS01120	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY144_RS01160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY144_RS01165	COG1609	Transcriptional regulator
FY144_RS01170	COG1653	transport
FY144_RS01175	COG1175	transmembrane transport
FY144_RS01180	COG0395	ABC-type sugar transport system, permease component
FY144_RS01185	COG0366	Alpha amylase catalytic
FY144_RS01190	COG3842	ATPase activity
FY144_RS01205	COG0129	dihydroxy-acid dehydratase activity
FY144_RS01210	COG0363	glucosamine-6-phosphate deaminase activity
FY144_RS01215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY144_RS01220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS01230	COG2081	HI0933 family
FY144_RS01250	COG2224	Isocitrate lyase
FY144_RS01265	COG3842	ATPase activity
FY144_RS01270	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY144_RS01275	COG1177	transmembrane transport
FY144_RS01285	COG2205	protein histidine kinase activity
FY144_RS01295	COG0248	Ppx GppA phosphatase
FY144_RS01300	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY144_RS01305	COG0477	Major facilitator Superfamily
FY144_RS01335	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY144_RS01340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY144_RS01350	COG0142	geranyltranstransferase activity
FY144_RS01375	COG0752	glycyl-tRNA synthetase alpha subunit
FY144_RS01385	COG1704	LemA family
FY144_RS01390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY144_RS01400	COG0751	glycine-tRNA ligase activity
FY144_RS01405	COG1683	Conserved Protein
FY144_RS01410	COG0840	transmembrane signaling receptor activity
FY144_RS01420	COG0151	Belongs to the GarS family
FY144_RS01425	COG2183	response to ionizing radiation
FY144_RS01430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY144_RS01455	COG0583	DNA-binding transcription factor activity
FY144_RS01475	COG0306	phosphate transporter
FY144_RS01485	COG0561	phosphatase activity
FY144_RS01490	COG0438	transferase activity, transferring glycosyl groups
FY144_RS01495	COG2186	Transcriptional regulator
FY144_RS01505	COG0583	DNA-binding transcription factor activity
FY144_RS01510	COG0277	FAD linked oxidase domain protein
FY144_RS01520	COG0247	lactate metabolic process
FY144_RS01530	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_RS01535	COG2818	Glycosylase
FY144_RS01545	COG2855	membrane
FY144_RS01550	COG0583	DNA-binding transcription factor activity
FY144_RS01580	COG0124	histidyl-tRNA synthetase
FY144_RS01590	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY144_RS01595	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY144_RS01600	COG2259	Doxx family
FY144_RS01610	COG0459	protein refolding
FY144_RS01615	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY144_RS01625	COG0196	riboflavin kinase activity
FY144_RS01630	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY144_RS01640	COG0590	tRNA wobble adenosine to inosine editing
FY144_RS01645	COG1187	pseudouridine synthase activity
FY144_RS01650	COG0742	ribosomal rna small subunit methyltransferase
FY144_RS01655	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY144_RS01665	COG0312	modulator of DNA gyrase
FY144_RS01670	COG0483	inositol monophosphate 1-phosphatase activity
FY144_RS01680	COG1519	Transferase
FY144_RS01690	COG1663	tetraacyldisaccharide 4'-kinase activity
FY144_RS01705	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY144_RS01710	COG0745	RESPONSE REGULATOR receiver
FY144_RS01715	COG5001	Diguanylate cyclase
FY144_RS01715	COG3300	MHYT domain
FY144_RS01720	COG3386	PFAM SMP-30 Gluconolaconase
FY144_RS01725	COG0800	Aldolase
FY144_RS01730	COG3734	2-keto-3-deoxy-galactonokinase
FY144_RS01735	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS01740	COG1414	Transcriptional regulator
FY144_RS01745	COG2197	response regulator
FY144_RS01760	COG0598	Magnesium transport protein CorA
FY144_RS01765	COG3158	transport of potassium into the cell
FY144_RS01780	COG0356	it plays a direct role in the translocation of protons across the membrane
FY144_RS01790	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY144_RS01795	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY144_RS01810	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY144_RS01830	COG0009	L-threonylcarbamoyladenylate synthase
FY144_RS01840	COG4638	Rieske (2fe-2S)
FY144_RS01865	COG1960	acyl-CoA dehydrogenase activity
FY144_RS01880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY144_RS01885	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY144_RS01890	COG0840	transmembrane signaling receptor activity
FY144_RS01900	COG1522	sequence-specific DNA binding
FY144_RS01925	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY144_RS01930	COG1741	Belongs to the pirin family
FY144_RS01935	COG1722	exodeoxyribonuclease VII activity
FY144_RS01940	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY144_RS01945	COG1268	BioY protein
FY144_RS01950	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY144_RS01955	COG1122	ATPase activity
FY144_RS01960	COG3214	Protein conserved in bacteria
FY144_RS01965	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY144_RS01965	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY144_RS01970	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY144_RS01990	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY144_RS02005	COG0259	pyridoxamine-phosphate oxidase activity
FY144_RS02035	COG0312	modulator of DNA gyrase
FY144_RS02050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY144_RS02055	COG0109	protoheme IX farnesyltransferase activity
FY144_RS02065	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY144_RS02080	COG3346	SURF1 family
FY144_RS02085	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY144_RS02090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY144_RS02095	COG0328	RNA-DNA hybrid ribonuclease activity
FY144_RS02105	COG0678	peroxiredoxin activity
FY144_RS02105	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY144_RS02115	COG1678	Uncharacterized ACR, COG1678
FY144_RS02120	COG3237	CsbD-like
FY144_RS02130	COG3300	MHYT domain
FY144_RS02130	COG5001	Diguanylate cyclase
FY144_RS02135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY144_RS02140	COG0612	Peptidase, M16
FY144_RS02165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY144_RS02170	COG1802	Transcriptional regulator
FY144_RS02185	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY144_RS02190	COG3609	addiction module antidote protein, CC2985 family
FY144_RS02195	COG3668	Plasmid stabilization system
FY144_RS02205	COG1194	a g-specific adenine glycosylase
FY144_RS02220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY144_RS02225	COG1196	nuclear chromosome segregation
FY144_RS02230	COG2514	catechol 2,3-dioxygenase activity
FY144_RS02235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY144_RS02235	COG0574	Belongs to the PEP-utilizing enzyme family
FY144_RS02250	COG1823	symporter activity
FY144_RS02280	COG0579	oxidoreductase
FY144_RS02295	COG2895	sulfate adenylyltransferase (ATP) activity
FY144_RS02300	COG0175	sulfate reduction
FY144_RS02305	COG0175	sulfate reduction
FY144_RS02310	COG1959	2 iron, 2 sulfur cluster binding
FY144_RS02315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY144_RS02320	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY144_RS02325	COG4208	sulfate ABC transporter
FY144_RS02330	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY144_RS02340	COG2199	diguanylate cyclase activity
FY144_RS02340	COG2200	EAL domain
FY144_RS02340	COG2203	Gaf domain
FY144_RS02350	COG1309	transcriptional regulator
FY144_RS02355	COG1012	belongs to the aldehyde dehydrogenase family
FY144_RS02360	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY144_RS02395	COG0625	glutathione transferase activity
FY144_RS02405	COG0477	Major facilitator Superfamily
FY144_RS02415	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY144_RS02415	COG1793	dna ligase
FY144_RS02435	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_RS02440	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_RS02445	COG1846	Transcriptional regulator
FY144_RS02450	COG1764	response to oxidative stress
FY144_RS02465	COG0488	(ABC) transporter
FY144_RS02500	COG4221	oxidoreductase activity
FY144_RS02515	COG0433	COG0433 Predicted ATPase
FY144_RS02525	COG1733	regulation of RNA biosynthetic process
FY144_RS02530	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY144_RS02545	COG0656	L-ascorbic acid biosynthetic process
FY144_RS02550	COG3781	membrane
FY144_RS02555	COG2378	regulation of single-species biofilm formation
FY144_RS02565	COG4106	trans-aconitate 2-methyltransferase activity
FY144_RS02570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY144_RS02575	COG0840	transmembrane signaling receptor activity
FY144_RS02580	COG0583	DNA-binding transcription factor activity
FY144_RS02595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY144_RS02615	COG3909	cytochrome
FY144_RS02620	COG2010	Cytochrome c
FY144_RS02650	COG0789	Transcriptional regulator
FY144_RS02675	COG0517	IMP dehydrogenase activity
FY144_RS02675	COG4175	Glycine betaine
FY144_RS02680	COG4176	ABC-type proline glycine betaine transport system permease component
FY144_RS02705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_RS02715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY144_RS02715	COG2169	Transcriptional regulator
FY144_RS02725	COG2514	catechol 2,3-dioxygenase activity
FY144_RS02745	COG1272	protein, Hemolysin III
FY144_RS02755	COG1280	lysine exporter protein (LysE YggA)
FY144_RS02760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY144_RS02765	COG2111	Na H antiporter
FY144_RS02765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY144_RS02770	COG2111	Na H antiporter
FY144_RS02775	COG1006	Multisubunit Na H antiporter MnhC subunit
FY144_RS02780	COG0651	ATP synthesis coupled electron transport
FY144_RS02785	COG1863	multisubunit Na H antiporter MnhE subunit
FY144_RS02790	COG2212	antiporter activity
FY144_RS02795	COG1320	monovalent cation:proton antiporter activity
FY144_RS02800	COG4957	zinc ion binding
FY144_RS02815	COG2166	iron-sulfur cluster assembly
FY144_RS02825	COG2205	protein histidine kinase activity
FY144_RS02865	COG0583	DNA-binding transcription factor activity
FY144_RS02870	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY144_RS02875	COG2983	Belongs to the UPF0260 family
FY144_RS02885	COG3041	Addiction module toxin RelE StbE family
FY144_RS02890	COG3077	Addiction module antitoxin, RelB DinJ family
FY144_RS02900	COG2217	Heavy metal translocating P-type atpase
FY144_RS02930	COG2814	Major facilitator Superfamily
FY144_RS02940	COG1621	beta-fructofuranosidase activity
FY144_RS02945	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY144_RS02995	COG4695	Portal protein
FY144_RS03095	COG4235	cytochrome complex assembly
FY144_RS03100	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY144_RS03105	COG1138	Cytochrome C-type biogenesis protein
FY144_RS03110	COG3088	subunit of a heme lyase
FY144_RS03115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY144_RS03120	COG0745	RESPONSE REGULATOR receiver
FY144_RS03125	COG2205	protein histidine kinase activity
FY144_RS03130	COG3011	Protein conserved in bacteria
FY144_RS03135	COG3713	MltA-interacting MipA family protein
FY144_RS03140	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY144_RS03145	COG2205	protein histidine kinase activity
FY144_RS03145	COG2202	Pas domain
FY144_RS03155	COG0308	aminopeptidase N
FY144_RS03160	COG0697	spore germination
FY144_RS03175	COG0443	Heat shock 70 kDa protein
FY144_RS03210	COG0604	alcohol dehydrogenase
FY144_RS03215	COG1733	regulation of RNA biosynthetic process
FY144_RS03220	COG1968	undecaprenyl-diphosphatase activity
FY144_RS03225	COG2239	Acts as a magnesium transporter
FY144_RS03230	COG2814	Major facilitator Superfamily
FY144_RS03255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY144_RS03285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY144_RS03330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FY144_RS03335	COG0741	lytic transglycosylase activity
FY144_RS03340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_RS03345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY144_RS03350	COG0840	transmembrane signaling receptor activity
FY144_RS03360	COG1758	RNA polymerase activity
FY144_RS03380	COG0736	holo-[acyl-carrier-protein] synthase activity
FY144_RS03385	COG0681	Belongs to the peptidase S26 family
FY144_RS03390	COG0571	ribonuclease III activity
FY144_RS03395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY144_RS03405	COG0784	Response regulator, receiver
FY144_RS03410	COG1381	Involved in DNA repair and RecF pathway recombination
FY144_RS03420	COG2226	methyltransferase
FY144_RS03425	COG0633	Ferredoxin
FY144_RS03425	COG3217	Mosc domain protein beta barrel domain protein
FY144_RS03430	COG1418	mRNA catabolic process
FY144_RS03440	COG0346	lactoylglutathione lyase activity
FY144_RS03455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_RS03460	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY144_RS03465	COG0668	transmembrane transport
FY144_RS03475	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY144_RS03505	COG1742	UPF0060 membrane protein
FY144_RS03525	COG1183	phosphatidylcholine synthase activity
FY144_RS03530	COG0688	phosphatidylethanolamine metabolic process
FY144_RS03535	COG5265	(ABC) transporter
FY144_RS03575	COG2852	Protein conserved in bacteria
FY144_RS03580	COG0215	cysteine-tRNA ligase activity
FY144_RS03585	COG4221	oxidoreductase activity
FY144_RS03590	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY144_RS03595	COG1286	toxin biosynthetic process
FY144_RS03615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY144_RS03625	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY144_RS03635	COG0305	Participates in initiation and elongation during chromosome replication
FY144_RS03655	COG0359	binds to the 23S rRNA
FY144_RS03665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY144_RS03670	COG0360	Binds together with S18 to 16S ribosomal RNA
FY144_RS03680	COG0667	Aldo Keto reductase
FY144_RS03685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY144_RS03695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY144_RS03700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY144_RS03710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY144_RS03715	COG1561	YicC-like family, N-terminal region
FY144_RS03720	COG0194	GDP metabolic process
FY144_RS03735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY144_RS03740	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY144_RS03750	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY144_RS03765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY144_RS03785	COG2203	Gaf domain
FY144_RS03785	COG5001	Diguanylate cyclase
FY144_RS03785	COG4251	negative regulation of phosphorylation
FY144_RS03785	COG3706	GGDEF domain
FY144_RS03790	COG5001	Diguanylate cyclase
FY144_RS03790	COG3300	MHYT domain
FY144_RS03795	COG4191	Histidine kinase
FY144_RS03800	COG4566	intracellular signal transduction
FY144_RS03810	COG0488	(ABC) transporter
FY144_RS03815	COG3706	GGDEF domain
FY144_RS03825	COG0105	UTP biosynthetic process
FY144_RS03845	COG0314	molybdopterin synthase activity
FY144_RS03855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY144_RS03860	COG0322	excinuclease ABC activity
FY144_RS03865	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS03890	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY144_RS03895	COG0243	molybdopterin cofactor binding
FY144_RS03920	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY144_RS03925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY144_RS03935	COG0628	permease
FY144_RS03945	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY144_RS03950	COG0248	Ppx GppA phosphatase
FY144_RS03975	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY144_RS03985	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY144_RS03990	COG0477	Major facilitator Superfamily
FY144_RS03995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY144_RS04005	COG0840	transmembrane signaling receptor activity
FY144_RS04010	COG0659	secondary active sulfate transmembrane transporter activity
FY144_RS04020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY144_RS04025	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY144_RS04035	COG0113	porphobilinogen synthase activity
FY144_RS04055	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY144_RS04060	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY144_RS04065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY144_RS04065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY144_RS04075	COG1280	lysine exporter protein (LysE YggA)
FY144_RS04080	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY144_RS04085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY144_RS04090	COG2814	Major facilitator Superfamily
FY144_RS04095	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY144_RS04115	COG0416	fatty acid biosynthetic process
FY144_RS04120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY144_RS04125	COG0776	regulation of translation
FY144_RS04160	COG0601	transmembrane transport
FY144_RS04165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS04170	COG0444	Belongs to the ABC transporter superfamily
FY144_RS04180	COG0747	negative chemotaxis
FY144_RS04190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY144_RS04195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY144_RS04210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY144_RS04215	COG0583	DNA-binding transcription factor activity
FY144_RS04220	COG0737	Belongs to the 5'-nucleotidase family
FY144_RS04240	COG2897	thiosulfate sulfurtransferase activity
FY144_RS04255	COG0415	Belongs to the DNA photolyase family
FY144_RS04265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY144_RS04295	COG3932	Exopolysaccharide synthesis, ExoD
FY144_RS04300	COG1238	metal cluster binding
FY144_RS04375	COG1612	heme a metabolic process
FY144_RS04385	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY144_RS04390	COG0010	Belongs to the arginase family
FY144_RS04395	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY144_RS04400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY144_RS04410	COG1832	CoA-binding protein
FY144_RS04435	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS04440	COG2124	cytochrome p450
FY144_RS04445	COG2199	diguanylate cyclase activity
FY144_RS04450	COG0740	serine-type endopeptidase activity
FY144_RS04455	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY144_RS04460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY144_RS04470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY144_RS04500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY144_RS04505	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY144_RS04510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY144_RS04520	COG0649	NAD binding
FY144_RS04530	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY144_RS04535	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY144_RS04545	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY144_RS04550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY144_RS04560	COG0713	ATP synthesis coupled electron transport
FY144_RS04575	COG1007	ATP synthesis coupled electron transport
FY144_RS04580	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY144_RS04580	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY144_RS04595	COG0442	prolyl-tRNA aminoacylation
FY144_RS04605	COG1136	(ABC) transporter
FY144_RS04620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY144_RS04640	COG0784	Response regulator, receiver
FY144_RS04650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY144_RS04655	COG0477	Major facilitator Superfamily
FY144_RS04670	COG0557	exoribonuclease II activity
FY144_RS04675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY144_RS04685	COG0758	DNA mediated transformation
FY144_RS04690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY144_RS04700	COG0540	Belongs to the ATCase OTCase family
FY144_RS04715	COG1960	acyl-CoA dehydrogenase activity
FY144_RS04720	COG0456	acetyltransferase
FY144_RS04740	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY144_RS04745	COG2824	Alkylphosphonate utilization operon protein PhnA
FY144_RS04750	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY144_RS04755	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY144_RS04760	COG0154	amidase activity
FY144_RS04765	COG0456	acetyltransferase
FY144_RS04770	COG3811	Belongs to the UPF0386 family
FY144_RS04785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY144_RS04795	COG0456	acetyltransferase
FY144_RS04815	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY144_RS04820	COG0439	Biotin carboxylase
FY144_RS04825	COG0511	ligase activity, forming carbon-carbon bonds
FY144_RS04830	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY144_RS04840	COG0436	Aminotransferase
FY144_RS04860	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS04865	COG1530	ribonuclease E activity
FY144_RS04875	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY144_RS04895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY144_RS04900	COG0384	phenazine biosynthesis protein PhzF
FY144_RS04920	COG0633	Ferredoxin
FY144_RS04930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FY144_RS04935	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY144_RS04940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY144_RS04950	COG3768	UPF0283 membrane protein
FY144_RS04955	COG3106	COG3106 Predicted ATPase
FY144_RS04985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY144_RS05020	COG0537	adenosine 5'-monophosphoramidase activity
FY144_RS05050	COG0052	Belongs to the universal ribosomal protein uS2 family
FY144_RS05055	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY144_RS05060	COG0528	UMP kinase activity
FY144_RS05065	COG0233	cytoplasmic translational termination
FY144_RS05070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY144_RS05080	COG0750	zinc metalloprotease
FY144_RS05085	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY144_RS05090	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY144_RS05095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY144_RS05100	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY144_RS05105	COG3494	Protein of unknown function (DUF1009)
FY144_RS05110	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY144_RS05115	COG2186	Transcriptional regulator
FY144_RS05125	COG0765	amino acid transport
FY144_RS05130	COG0765	amino acid transport
FY144_RS05140	COG0372	Belongs to the citrate synthase family
FY144_RS05155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY144_RS05165	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY144_RS05170	COG0148	phosphopyruvate hydratase activity
FY144_RS05180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY144_RS05185	COG0022	dehydrogenase e1 component
FY144_RS05185	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY144_RS05190	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY144_RS05200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY144_RS05210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY144_RS05215	COG0697	spore germination
FY144_RS05235	COG2867	negative regulation of translational initiation
FY144_RS05240	COG1546	Belongs to the CinA family
FY144_RS05240	COG1058	Belongs to the CinA family
FY144_RS05245	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY144_RS05245	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY144_RS05255	COG3852	Histidine kinase
FY144_RS05260	COG2204	response regulator
FY144_RS05265	COG5000	phosphorelay sensor kinase activity
FY144_RS05270	COG2204	response regulator
FY144_RS05275	COG0569	domain protein
FY144_RS05280	COG1923	regulation of RNA biosynthetic process
FY144_RS05285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY144_RS05290	COG3956	TIGRFAM MazG family protein
FY144_RS05300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY144_RS05300	COG1648	precorrin-2 dehydrogenase activity
FY144_RS05340	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY144_RS05340	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY144_RS05345	COG0509	glycine decarboxylation via glycine cleavage system
FY144_RS05350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY144_RS05375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY144_RS05380	COG0564	pseudouridine synthase activity
FY144_RS05400	COG0251	oxidation-reduction process
FY144_RS05405	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY144_RS05415	COG1671	Belongs to the UPF0178 family
FY144_RS05430	COG0450	alkyl hydroperoxide reductase
FY144_RS05440	COG0625	glutathione transferase activity
FY144_RS05460	COG2826	transposase and inactivated derivatives, IS30 family
FY144_RS05465	COG0431	NADPH-dependent FMN reductase
FY144_RS05475	COG0798	PFAM Bile acid sodium symporter
FY144_RS05480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY144_RS05495	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY144_RS05495	COG0321	lipoyl(octanoyl) transferase activity
FY144_RS05500	COG0084	hydrolase, TatD family'
FY144_RS05505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY144_RS05515	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY144_RS05570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY144_RS05575	COG2095	MarC family integral membrane protein
FY144_RS05580	COG0517	IMP dehydrogenase activity
FY144_RS05580	COG0617	tRNA 3'-terminal CCA addition
FY144_RS05580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY144_RS05590	COG0629	single-stranded DNA binding
FY144_RS05595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY144_RS05605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY144_RS05625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY144_RS05630	COG1121	(ABC) transporter
FY144_RS05650	COG0667	Aldo Keto reductase
FY144_RS05660	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY144_RS05740	COG2239	Acts as a magnesium transporter
FY144_RS05745	COG0243	molybdopterin cofactor binding
FY144_RS05755	COG0242	peptide deformylase activity
FY144_RS05770	COG2205	protein histidine kinase activity
FY144_RS05770	COG2202	Pas domain
FY144_RS05780	COG0321	lipoyl(octanoyl) transferase activity
FY144_RS05785	COG1064	alcohol dehydrogenase
FY144_RS05815	COG1862	Preprotein translocase
FY144_RS05835	COG2124	cytochrome p450
FY144_RS05850	COG0596	Alpha beta hydrolase
FY144_RS05860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY144_RS05865	COG0626	cystathionine gamma-synthase activity
FY144_RS05870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_RS05875	COG4597	amino acid ABC transporter
FY144_RS05880	COG0765	amino acid transport
FY144_RS05885	COG1126	abc transporter atp-binding protein
FY144_RS05900	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY144_RS05915	COG0436	Aminotransferase
FY144_RS05945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY144_RS05955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY144_RS05960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY144_RS05965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY144_RS05980	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY144_RS05985	COG1489	DNA binding
FY144_RS05990	COG0024	Methionine aminopeptidase
FY144_RS06010	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY144_RS06035	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY144_RS06040	COG0546	phosphoglycolate phosphatase activity
FY144_RS06050	COG0114	fumarate hydratase activity
FY144_RS06060	COG0504	CTP synthase activity
FY144_RS06070	COG0149	triose-phosphate isomerase activity
FY144_RS06080	COG0187	DNA topoisomerase II activity
FY144_RS06090	COG0740	serine-type endopeptidase activity
FY144_RS06100	COG0640	Transcriptional regulator
FY144_RS06105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY144_RS06110	COG0745	RESPONSE REGULATOR receiver
FY144_RS06130	COG3264	Mechanosensitive ion channel
FY144_RS06130	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY144_RS06195	COG1127	ABC transporter
FY144_RS06200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY144_RS06205	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_RS06215	COG0280	phosphate acetyltransferase
FY144_RS06215	COG0281	malic enzyme
FY144_RS06225	COG0778	Nitroreductase
FY144_RS06230	COG0823	Involved in the tonB-independent uptake of proteins
FY144_RS06245	COG1368	sulfuric ester hydrolase activity
FY144_RS06270	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY144_RS06290	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY144_RS06310	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY144_RS06325	COG0318	PFAM AMP-dependent synthetase and ligase
FY144_RS06335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY144_RS06335	COG0512	Glutamine amidotransferase of anthranilate synthase
FY144_RS06340	COG0343	queuine tRNA-ribosyltransferase activity
FY144_RS06345	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY144_RS06360	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY144_RS06380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY144_RS06385	COG0134	indole-3-glycerol-phosphate synthase activity
FY144_RS06390	COG0315	cyclic pyranopterin monophosphate synthase activity
FY144_RS06395	COG0303	'Molybdopterin
FY144_RS06400	COG3706	GGDEF domain
FY144_RS06410	COG0475	glutathione-regulated potassium exporter activity
FY144_RS06410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY144_RS06420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY144_RS06430	COG2814	Major facilitator Superfamily
FY144_RS06435	COG0746	molybdenum cofactor guanylyltransferase activity
FY144_RS06440	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY144_RS06445	COG0739	heme binding
FY144_RS06450	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY144_RS06455	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY144_RS06460	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY144_RS06465	COG0805	protein transport
FY144_RS06470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY144_RS06475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY144_RS06480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY144_RS06485	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY144_RS06490	COG1472	Belongs to the glycosyl hydrolase 3 family
FY144_RS06500	COG0018	arginyl-trna synthetase
FY144_RS06505	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY144_RS06530	COG0525	valine-tRNA ligase activity
FY144_RS06540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY144_RS06570	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY144_RS06575	COG1058	Belongs to the CinA family
FY144_RS06575	COG1546	Belongs to the CinA family
FY144_RS06580	COG0589	response to stress
FY144_RS06585	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY144_RS06600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY144_RS06610	COG0640	Transcriptional regulator
FY144_RS06615	COG1914	H( )-stimulated, divalent metal cation uptake system
FY144_RS06625	COG1132	(ABC) transporter
FY144_RS06630	COG0628	permease
FY144_RS06665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY144_RS06675	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY144_RS06685	COG0302	gtp cyclohydrolase
FY144_RS06690	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY144_RS06695	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY144_RS06705	COG0516	GMP reductase activity
FY144_RS06705	COG0517	IMP dehydrogenase activity
FY144_RS06740	COG1760	l-serine dehydratase
FY144_RS06780	COG0583	DNA-binding transcription factor activity
FY144_RS06795	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY144_RS06795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY144_RS06805	COG0347	Belongs to the P(II) protein family
FY144_RS06810	COG0174	glutamine synthetase
FY144_RS06840	COG0697	spore germination
FY144_RS06850	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY144_RS06860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY144_RS06890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY144_RS06900	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY144_RS06905	COG2186	Transcriptional regulator
FY144_RS06915	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY144_RS06920	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY144_RS06925	COG3845	ABC transporter
FY144_RS06930	COG1183	phosphatidylcholine synthase activity
FY144_RS06935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY144_RS06940	COG0679	Auxin Efflux Carrier
FY144_RS06945	COG0785	Cytochrome C biogenesis protein
FY144_RS06965	COG1278	Cold shock
FY144_RS07030	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY144_RS07050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY144_RS07145	COG3685	Protein conserved in bacteria
FY144_RS07160	COG0393	Putative heavy-metal-binding
FY144_RS07215	COG0616	signal peptide processing
FY144_RS07270	COG2815	serine threonine protein kinase
FY144_RS07270	COG0515	serine threonine protein kinase
FY144_RS07280	COG3237	CsbD-like
FY144_RS07290	COG0270	DNA (cytosine-5-)-methyltransferase activity
FY144_RS07320	COG1061	Type III restriction enzyme res subunit
FY144_RS07435	COG0582	viral genome integration into host DNA
FY144_RS07455	COG0577	efflux transmembrane transporter activity
FY144_RS07455	COG1136	(ABC) transporter
FY144_RS07460	COG0577	efflux transmembrane transporter activity
FY144_RS07460	COG1136	(ABC) transporter
FY144_RS07485	COG2151	metal-sulfur cluster biosynthetic enzyme
FY144_RS07490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY144_RS07495	COG0719	Fe-S assembly protein
FY144_RS07500	COG0396	ATPase activity
FY144_RS07505	COG0719	Fe-S assembly protein
FY144_RS07510	COG1104	cysteine desulfurase activity
FY144_RS07515	COG2945	thiolester hydrolase activity
FY144_RS07520	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY144_RS07525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY144_RS07535	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY144_RS07540	COG2833	Protein of unknown function (DUF455)
FY144_RS07545	COG0739	heme binding
FY144_RS07550	COG0513	Belongs to the DEAD box helicase family
FY144_RS07575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY144_RS07585	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY144_RS07590	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY144_RS07595	COG0047	phosphoribosylformylglycinamidine synthase activity
FY144_RS07610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY144_RS07615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY144_RS07640	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY144_RS07645	COG2814	Major facilitator Superfamily
FY144_RS07650	COG0483	inositol monophosphate 1-phosphatase activity
FY144_RS07655	COG0483	inositol monophosphate 1-phosphatase activity
FY144_RS07660	COG0037	tRNA processing
FY144_RS07665	COG2066	Belongs to the glutaminase family
FY144_RS07670	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY144_RS07675	COG0861	Integral membrane protein TerC family
FY144_RS07690	COG1280	lysine exporter protein (LysE YggA)
FY144_RS07700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY144_RS07705	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY144_RS07715	COG0538	isocitrate dehydrogenase activity
FY144_RS07725	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY144_RS07730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY144_RS07735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_RS07740	COG2313	pseudouridylate synthase activity
FY144_RS07750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_RS07755	COG4215	(ABC) transporter
FY144_RS07765	COG5425	PFAM Usg family protein
FY144_RS07775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_RS07780	COG1522	sequence-specific DNA binding
FY144_RS07785	COG1573	uracil-dna glycosylase
FY144_RS07795	COG2205	protein histidine kinase activity
FY144_RS07795	COG2202	Pas domain
FY144_RS07800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY144_RS07805	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY144_RS07810	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY144_RS07825	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY144_RS07830	COG0842	Transport permease protein
FY144_RS07835	COG1131	(ABC) transporter
FY144_RS07840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY144_RS07840	COG0730	response to heat
FY144_RS07860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY144_RS07865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY144_RS07885	COG0129	dihydroxy-acid dehydratase activity
FY144_RS07890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY144_RS07895	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY144_RS07905	COG3739	integral membrane protein
FY144_RS07915	COG0203	ribosomal protein L17
FY144_RS07920	COG0202	RNA polymerase activity
FY144_RS07925	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY144_RS07930	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY144_RS07935	COG0563	adenylate kinase activity
FY144_RS07940	COG0201	protein transport
FY144_RS07945	COG0200	Binds to the 23S rRNA
FY144_RS07950	COG1841	ribosomal large subunit assembly
FY144_RS07955	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY144_RS07960	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY144_RS07965	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY144_RS07970	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY144_RS07975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY144_RS07980	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY144_RS07985	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY144_RS07990	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY144_RS07995	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY144_RS08000	COG0255	Belongs to the universal ribosomal protein uL29 family
FY144_RS08005	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY144_RS08010	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY144_RS08015	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY144_RS08020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY144_RS08025	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY144_RS08030	COG0089	rRNA binding
FY144_RS08035	COG0088	Forms part of the polypeptide exit tunnel
FY144_RS08040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY144_RS08045	COG0051	transcription antitermination factor activity, RNA binding
FY144_RS08050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY144_RS08055	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY144_RS08060	COG0049	tRNA binding
FY144_RS08065	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY144_RS08085	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY144_RS08090	COG0085	RNA polymerase activity
FY144_RS08095	COG0222	ribosome binding
FY144_RS08100	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY144_RS08105	COG0081	regulation of translation
FY144_RS08110	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY144_RS08120	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY144_RS08130	COG1086	Polysaccharide biosynthesis protein
FY144_RS08135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY144_RS08140	COG0861	Integral membrane protein TerC family
FY144_RS08165	COG1132	(ABC) transporter
FY144_RS08170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY144_RS08190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY144_RS08225	COG2205	protein histidine kinase activity
FY144_RS08225	COG0784	Response regulator, receiver
FY144_RS08225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_RS08225	COG2198	Histidine kinase
FY144_RS08230	COG0784	Response regulator, receiver
FY144_RS08235	COG3920	Histidine kinase
FY144_RS08235	COG2202	Pas domain
FY144_RS08240	COG0784	Response regulator, receiver
FY144_RS08245	COG4251	negative regulation of phosphorylation
FY144_RS08260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY144_RS08265	COG1607	acyl-coa hydrolase
FY144_RS08285	COG2910	NAD(P)H-binding
FY144_RS08290	COG1733	regulation of RNA biosynthetic process
FY144_RS08305	COG0556	nucleotide-excision repair
FY144_RS08315	COG2382	esterase
FY144_RS08335	COG0484	heat shock protein binding
FY144_RS08355	COG3706	GGDEF domain
FY144_RS08375	COG1840	ABC-type Fe3 transport system, periplasmic component
FY144_RS08380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY144_RS08395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY144_RS08405	COG2207	Transcriptional regulator
FY144_RS08410	COG1064	alcohol dehydrogenase
FY144_RS08415	COG1252	NADH dehydrogenase
FY144_RS08420	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY144_RS08425	COG2197	response regulator
FY144_RS08430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY144_RS08465	COG0656	L-ascorbic acid biosynthetic process
FY144_RS08480	COG0440	acetolactate synthase activity
FY144_RS08485	COG0028	Belongs to the TPP enzyme family
FY144_RS08500	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY144_RS08505	COG3830	Belongs to the UPF0237 family
FY144_RS08505	COG0560	Phosphoserine phosphatase
FY144_RS08525	COG0330	HflC and HflK could
FY144_RS08530	COG0330	HflC and HflK could
FY144_RS08540	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY144_RS08575	COG0277	FAD linked oxidase domain protein
FY144_RS08580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY144_RS08620	COG1335	isochorismatase
FY144_RS08650	COG2264	protein methyltransferase activity
FY144_RS08655	COG1999	signal sequence binding
FY144_RS08665	COG0835	chemotaxis
FY144_RS08675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY144_RS08680	COG0583	DNA-binding transcription factor activity
FY144_RS08690	COG1247	-acetyltransferase
FY144_RS08700	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY144_RS08705	COG0497	DNA recombination
FY144_RS08710	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY144_RS08720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY144_RS08725	COG0849	cell division
FY144_RS08730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY144_RS08735	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY144_RS08740	COG0477	Major facilitator Superfamily
FY144_RS08750	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY144_RS08755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY144_RS08760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY144_RS08770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY144_RS08775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY144_RS08785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY144_RS08800	COG0275	rRNA processing
FY144_RS08805	COG2001	Belongs to the MraZ family
FY144_RS08830	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY144_RS08860	COG4106	trans-aconitate 2-methyltransferase activity
FY144_RS08880	COG2226	methyltransferase
FY144_RS08890	COG2267	carboxylic ester hydrolase activity
FY144_RS08895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY144_RS08925	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_RS08930	COG2814	Major facilitator Superfamily
FY144_RS08965	COG1012	belongs to the aldehyde dehydrogenase family
FY144_RS08970	COG0174	glutamine synthetase
FY144_RS08975	COG0531	amino acid
FY144_RS08990	COG2182	Extracellular solute-binding protein
FY144_RS09005	COG3842	ATPase activity
FY144_RS09065	COG2968	Membrane
FY144_RS09075	COG0432	Pfam Uncharacterised protein family UPF0047
FY144_RS09090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY144_RS09095	COG0358	DNA primase activity
FY144_RS09115	COG0505	Belongs to the CarA family
FY144_RS09120	COG0534	Mate efflux family protein
FY144_RS09135	COG2321	neutral zinc metallopeptidase
FY144_RS09150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY144_RS09160	COG3706	GGDEF domain
FY144_RS09175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY144_RS09185	COG1522	sequence-specific DNA binding
FY144_RS09190	COG0492	ferredoxin-NADP+ reductase activity
FY144_RS09195	COG0583	DNA-binding transcription factor activity
FY144_RS09205	COG1902	pentaerythritol trinitrate reductase activity
FY144_RS09230	COG0387	Pfam Sodium calcium exchanger
FY144_RS09235	COG0436	Aminotransferase
FY144_RS09240	COG2200	EAL domain
FY144_RS09240	COG2199	diguanylate cyclase activity
FY144_RS09255	COG1278	Cold shock
FY144_RS09260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY144_RS09270	COG1846	Transcriptional regulator
FY144_RS09275	COG0745	RESPONSE REGULATOR receiver
FY144_RS09285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY144_RS09305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY144_RS09315	COG1496	oxidoreductase activity
FY144_RS09330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY144_RS09340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY144_RS09355	COG0840	transmembrane signaling receptor activity
FY144_RS09360	COG1012	belongs to the aldehyde dehydrogenase family
FY144_RS09365	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY144_RS09370	COG5001	Diguanylate cyclase
FY144_RS09370	COG3300	MHYT domain
FY144_RS09375	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY144_RS09380	COG5001	Diguanylate cyclase
FY144_RS09390	COG0193	aminoacyl-tRNA hydrolase activity
FY144_RS09400	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY144_RS09425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY144_RS09435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY144_RS09435	COG2857	Cytochrome c1
FY144_RS09455	COG1132	(ABC) transporter
FY144_RS09460	COG1132	(ABC) transporter
FY144_RS09470	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY144_RS09485	COG0408	coproporphyrinogen oxidase activity
FY144_RS09500	COG0617	tRNA 3'-terminal CCA addition
FY144_RS09515	COG0714	Associated with various cellular activities
FY144_RS09535	COG0454	-acetyltransferase
FY144_RS09550	COG0477	Major facilitator Superfamily
FY144_RS09560	COG0435	Glutathione S-transferase
FY144_RS09565	COG0494	nUDIX hydrolase
FY144_RS09575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY144_RS09580	COG3135	benzoate transporter
FY144_RS09605	COG0740	serine-type endopeptidase activity
FY144_RS09620	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY144_RS09625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY144_RS09650	COG4175	Glycine betaine
FY144_RS09670	COG1435	thymidine kinase activity
FY144_RS09695	COG1629	transport
FY144_RS09695	COG4771	TonB-dependent receptor
FY144_RS09705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY144_RS09705	COG0512	Glutamine amidotransferase of anthranilate synthase
FY144_RS09720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY144_RS09730	COG0366	Alpha amylase catalytic
FY144_RS09735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_RS09755	COG1160	GTP binding
FY144_RS09775	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY144_RS09785	COG0024	Methionine aminopeptidase
FY144_RS09795	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS09805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY144_RS09815	COG0583	DNA-binding transcription factor activity
FY144_RS09835	COG0402	S-adenosylhomocysteine deaminase activity
FY144_RS09855	COG1309	transcriptional regulator
FY144_RS09860	COG1686	Belongs to the peptidase S11 family
FY144_RS09870	COG2351	hydroxyisourate hydrolase activity
FY144_RS09875	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY144_RS09890	COG3195	allantoin biosynthetic process
FY144_RS09890	COG3648	Uricase
FY144_RS09900	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY144_RS09910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS09910	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY144_RS09920	COG0513	Belongs to the DEAD box helicase family
FY144_RS09935	COG2259	Doxx family
FY144_RS09940	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_RS09950	COG2308	Evidence 4 Homologs of previously reported genes of
FY144_RS09960	COG1305	Transglutaminase-like
FY144_RS09990	COG4214	carbohydrate transport
FY144_RS09995	COG1129	ABC transporter
FY144_RS10000	COG4213	ABC transporter substrate-binding protein
FY144_RS10130	COG0646	methionine synthase
FY144_RS10130	COG1410	methionine synthase
FY144_RS10175	COG1215	transferase activity, transferring glycosyl groups
FY144_RS10205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY144_RS10230	COG1309	transcriptional regulator
FY144_RS10245	COG0494	nUDIX hydrolase
FY144_RS10255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_RS10260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_RS10290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY144_RS10295	COG0830	nickel cation binding
FY144_RS10300	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY144_RS10315	COG0804	urea catabolic process
FY144_RS10320	COG1442	glycosyl transferase family 8
FY144_RS10335	COG0832	Belongs to the urease beta subunit family
FY144_RS10340	COG3813	Protein conserved in bacteria
FY144_RS10345	COG0831	urea catabolic process
FY144_RS10350	COG0829	nickel cation binding
FY144_RS10380	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY144_RS10400	COG0174	glutamine synthetase
FY144_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS10410	COG2198	Histidine kinase
FY144_RS10410	COG0784	Response regulator, receiver
FY144_RS10410	COG5002	protein histidine kinase activity
FY144_RS10425	COG0726	polysaccharide deacetylase
FY144_RS10460	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY144_RS10535	COG0564	pseudouridine synthase activity
FY144_RS10545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY144_RS10555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY144_RS10580	COG0346	lactoylglutathione lyase activity
FY144_RS10590	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY144_RS10600	COG2832	Protein of unknown function (DUF454)
FY144_RS10605	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY144_RS10610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_RS10615	COG4558	Periplasmic binding protein
FY144_RS10625	COG3721	Heme iron utilization protein
FY144_RS10640	COG3655	Transcriptional regulator
FY144_RS10655	COG3657	addiction module killer protein
FY144_RS10665	COG2205	protein histidine kinase activity
FY144_RS10710	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_RS10715	COG4605	iron ion homeostasis
FY144_RS10720	COG4604	ABC transporter, ATP-binding protein
FY144_RS10725	COG0783	Belongs to the Dps family
FY144_RS10740	COG0840	transmembrane signaling receptor activity
FY144_RS10740	COG2972	Histidine kinase
FY144_RS10745	COG0656	L-ascorbic acid biosynthetic process
FY144_RS10750	COG2814	Major facilitator Superfamily
FY144_RS10760	COG0583	DNA-binding transcription factor activity
FY144_RS10765	COG0657	acetylesterase activity
FY144_RS10770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_RS10790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY144_RS10795	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY144_RS10800	COG0288	reversible hydration of carbon dioxide
FY144_RS10810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY144_RS10830	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY144_RS10835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY144_RS10840	COG0778	Nitroreductase
FY144_RS10845	COG2267	carboxylic ester hydrolase activity
FY144_RS10850	COG0251	oxidation-reduction process
FY144_RS10855	COG1335	isochorismatase
FY144_RS10860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS10870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_RS10885	COG1175	transmembrane transport
FY144_RS10890	COG0395	ABC-type sugar transport system, permease component
FY144_RS10895	COG3842	ATPase activity
FY144_RS10900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_RS10910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY144_RS10925	COG4608	Belongs to the ABC transporter superfamily
FY144_RS10930	COG0444	Belongs to the ABC transporter superfamily
FY144_RS10935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS10940	COG0601	transmembrane transport
FY144_RS10995	COG2159	amidohydrolase
FY144_RS11000	COG1960	acyl-CoA dehydrogenase activity
FY144_RS11030	COG0745	RESPONSE REGULATOR receiver
FY144_RS11040	COG1902	pentaerythritol trinitrate reductase activity
FY144_RS11040	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY144_RS11045	COG3842	ATPase activity
FY144_RS11055	COG1840	ABC-type Fe3 transport system, periplasmic component
FY144_RS11060	COG1840	ABC-type Fe3 transport system, periplasmic component
FY144_RS11065	COG0745	RESPONSE REGULATOR receiver
FY144_RS11075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY144_RS11080	COG0583	DNA-binding transcription factor activity
FY144_RS11085	COG1278	Cold shock
FY144_RS11090	COG4372	Transposase
FY144_RS11095	COG3436	PFAM IS66 Orf2 family protein
FY144_RS11135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY144_RS11140	COG1309	transcriptional regulator
FY144_RS11145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_RS11150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY144_RS11160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY144_RS11165	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY144_RS11185	COG0583	DNA-binding transcription factor activity
FY144_RS11190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS11195	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY144_RS11200	COG4149	molybdate abc transporter
FY144_RS11205	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY144_RS11220	COG2022	thiamine diphosphate biosynthetic process
FY144_RS11235	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY144_RS11240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY144_RS11250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY144_RS11270	COG1132	(ABC) transporter
FY144_RS11275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY144_RS11320	COG4166	transmembrane transport
FY144_RS11325	COG0601	transmembrane transport
FY144_RS11330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS11345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY144_RS11350	COG3142	Participates in the control of copper homeostasis
FY144_RS11355	COG2814	Major facilitator Superfamily
FY144_RS11370	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS11375	COG1737	Transcriptional regulator
FY144_RS11385	COG3842	ATPase activity
FY144_RS11395	COG0395	ABC-type sugar transport system, permease component
FY144_RS11415	COG2188	Transcriptional regulator
FY144_RS11420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY144_RS11425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY144_RS11430	COG1940	carbohydrate kinase activity
FY144_RS11440	COG0671	phosphoesterase, PA-phosphatase related
FY144_RS11445	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY144_RS11450	COG0156	8-amino-7-oxononanoate synthase activity
FY144_RS11460	COG0729	surface antigen
FY144_RS11470	COG0835	chemotaxis
FY144_RS11480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY144_RS11485	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY144_RS11490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY144_RS11495	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY144_RS11500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY144_RS11505	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY144_RS11520	COG4974	Belongs to the 'phage' integrase family
FY144_RS11545	COG1280	lysine exporter protein (LysE YggA)
FY144_RS11555	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY144_RS11560	COG0567	Dehydrogenase, E1 component
FY144_RS11565	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY144_RS11570	COG0045	succinate-CoA ligase (ADP-forming) activity
FY144_RS11575	COG0039	L-malate dehydrogenase activity
FY144_RS11580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY144_RS11615	COG2264	protein methyltransferase activity
FY144_RS11630	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY144_RS11635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY144_RS11640	COG0181	hydroxymethylbilane synthase activity
FY144_RS11680	COG1872	DUF167
FY144_RS11685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY144_RS11695	COG1217	gtp-binding protein TYPA
FY144_RS11700	COG0339	signal peptide processing
FY144_RS11705	COG1846	Transcriptional regulator
FY144_RS11715	COG0137	argininosuccinate synthase activity
FY144_RS11725	COG1280	lysine exporter protein (LysE YggA)
FY144_RS11730	COG1122	ATPase activity
FY144_RS11735	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY144_RS11745	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY144_RS11760	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY144_RS11765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY144_RS11770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY144_RS11780	COG4181	ATPase activity
FY144_RS11790	COG0670	Belongs to the BI1 family
FY144_RS11805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY144_RS11810	COG4133	protoheme IX ABC transporter activity
FY144_RS11815	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY144_RS11820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY144_RS11845	COG2917	probably involved in intracellular septation
FY144_RS11850	COG0552	protein localization to endoplasmic reticulum
FY144_RS11855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY144_RS11860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY144_RS11875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY144_RS11880	COG1605	Chorismate mutase
FY144_RS11880	COG0287	Prephenate dehydrogenase
FY144_RS11885	COG0228	four-way junction DNA binding
FY144_RS11890	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY144_RS11895	COG0336	Belongs to the RNA methyltransferase TrmD family
FY144_RS11905	COG0335	large ribosomal subunit rRNA binding
FY144_RS11910	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY144_RS11915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_RS11930	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY144_RS11950	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY144_RS11970	COG0488	(ABC) transporter
FY144_RS11980	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY144_RS11990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY144_RS11995	COG0142	geranyltranstransferase activity
FY144_RS12000	COG2885	chlorophyll binding
FY144_RS12005	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY144_RS12010	COG2223	nitrite transmembrane transporter activity
FY144_RS12015	COG1349	DNA-binding transcription factor activity
FY144_RS12020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY144_RS12025	COG2197	response regulator
FY144_RS12030	COG1132	(ABC) transporter
FY144_RS12035	COG3459	Glycosyltransferase 36 associated
FY144_RS12040	COG1473	amidohydrolase
FY144_RS12050	COG0579	oxidoreductase
FY144_RS12060	COG0129	dihydroxy-acid dehydratase activity
FY144_RS12065	COG2084	Dehydrogenase
FY144_RS12070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_RS12075	COG0277	FAD linked oxidase domain protein
FY144_RS12080	COG2186	Transcriptional regulator
FY144_RS12090	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY144_RS12095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY144_RS12100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_RS12105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY144_RS12115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY144_RS12120	COG0495	leucyl-tRNA aminoacylation
FY144_RS12135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY144_RS12140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY144_RS12155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY144_RS12160	COG1946	Acyl-CoA thioesterase
FY144_RS12165	COG0347	Belongs to the P(II) protein family
FY144_RS12170	COG0004	ammonium transporteR
FY144_RS12175	COG1674	ftsk spoiiie
FY144_RS12180	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY144_RS12195	COG0745	RESPONSE REGULATOR receiver
FY144_RS12205	COG1329	Transcriptional regulator
FY144_RS12215	COG2270	Major facilitator Superfamily
FY144_RS12230	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS12245	COG0494	nUDIX hydrolase
FY144_RS12250	COG2861	carbohydrate metabolic process
FY144_RS12255	COG0793	Belongs to the peptidase S41A family
FY144_RS12265	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY144_RS12270	COG0799	negative regulation of ribosome biogenesis
FY144_RS12275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY144_RS12280	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY144_RS12285	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY144_RS12290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY144_RS12305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY144_RS12310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY144_RS12335	COG0066	3-isopropylmalate dehydratase activity
FY144_RS12340	COG0473	3-isopropylmalate dehydrogenase activity
FY144_RS12345	COG1858	cytochrome C peroxidase
FY144_RS12350	COG1797	cobyrinic acid a,c-diamide synthase activity
FY144_RS12360	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY144_RS12425	COG1492	cobalamin metabolic process
FY144_RS12440	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_RS12445	COG3254	rhamnose metabolic process
FY144_RS12450	COG0246	Mannitol dehydrogenase
FY144_RS12455	COG1063	alcohol dehydrogenase
FY144_RS12480	COG1129	ABC transporter
FY144_RS12485	COG2186	Transcriptional regulator
FY144_RS12490	COG2721	sulfolactate sulfo-lyase activity
FY144_RS12495	COG0138	bifunctional purine biosynthesis protein purh
FY144_RS12505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY144_RS12505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY144_RS12510	COG0501	Belongs to the peptidase M48B family
FY144_RS12530	COG0357	Ribosomal RNA small subunit methyltransferase G
FY144_RS12535	COG0445	tRNA wobble uridine modification
FY144_RS12540	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY144_RS12545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY144_RS12550	COG1981	membrane
FY144_RS12555	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY144_RS12560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY144_RS12565	COG0424	maF-like protein
FY144_RS12570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY144_RS12575	COG0237	dephospho-CoA kinase activity
FY144_RS12585	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY144_RS12590	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY144_RS12600	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY144_RS12625	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY144_RS12640	COG0135	phosphoribosylanthranilate isomerase activity
FY144_RS12645	COG0133	tryptophan synthase activity
FY144_RS12650	COG0159	tryptophan synthase activity
FY144_RS12655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY144_RS12670	COG1074	ATP-dependent DNA helicase activity
FY144_RS12680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY144_RS12685	COG0802	atpase or kinase
FY144_RS12690	COG2205	protein histidine kinase activity
FY144_RS12695	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY144_RS12700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY144_RS12705	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY144_RS12705	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY144_RS12710	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY144_RS12715	COG0642	Histidine kinase
FY144_RS12720	COG0745	RESPONSE REGULATOR receiver
FY144_RS12725	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY144_RS12735	COG1652	LysM domain
FY144_RS12740	COG1072	(Pantothenic acid kinase))
FY144_RS12745	COG0140	phosphoribosyl-ATP diphosphatase activity
FY144_RS12750	COG0107	imidazoleglycerol-phosphate synthase activity
FY144_RS12755	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY144_RS12760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY144_RS12770	COG0131	Imidazoleglycerol-phosphate dehydratase
FY144_RS12775	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY144_RS12780	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY144_RS12790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY144_RS12805	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY144_RS12815	COG1643	Atp-dependent helicase
FY144_RS12855	COG1940	carbohydrate kinase activity
FY144_RS12875	COG1072	(Pantothenic acid kinase))
FY144_RS12885	COG1780	Probably involved in ribonucleotide reductase function
FY144_RS12905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY144_RS12935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_RS12945	COG2813	Specifically methylates the guanine in position
FY144_RS12950	COG1185	polyribonucleotide nucleotidyltransferase activity
FY144_RS12955	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY144_RS12960	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY144_RS12965	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY144_RS12970	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY144_RS12970	COG3064	Membrane
FY144_RS12985	COG0779	Required for maturation of 30S ribosomal subunits
FY144_RS12990	COG2814	Major facilitator Superfamily
FY144_RS12995	COG2951	lytic endotransglycosylase activity
FY144_RS13000	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY144_RS13010	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY144_RS13015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY144_RS13030	COG2816	NAD+ diphosphatase activity
FY144_RS13035	COG0077	Prephenate dehydratase
FY144_RS13035	COG1605	Chorismate mutase
FY144_RS13040	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY144_RS13045	COG3474	cytochrome
FY144_RS13055	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY144_RS13060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY144_RS13065	COG1278	Cold shock
FY144_RS13070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY144_RS13080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY144_RS13080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY144_RS13085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY144_RS13115	COG2900	Belongs to the SlyX family
FY144_RS13125	COG0484	heat shock protein binding
FY144_RS13130	COG0443	Heat shock 70 kDa protein
FY144_RS13145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY144_RS13150	COG1744	ABC transporter substrate-binding protein PnrA-like
FY144_RS13155	COG3845	ABC transporter
FY144_RS13160	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY144_RS13165	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY144_RS13170	COG0295	cytidine deaminase activity
FY144_RS13175	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY144_RS13180	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY144_RS13185	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY144_RS13195	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY144_RS13200	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY144_RS13205	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY144_RS13215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY144_RS13220	COG1845	cytochrome c oxidase, subunit III
FY144_RS13225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY144_RS13230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY144_RS13235	COG0477	Major facilitator Superfamily
FY144_RS13240	COG0069	glutamate synthase activity
FY144_RS13240	COG0067	glutamate synthase
FY144_RS13240	COG0070	glutamate synthase
FY144_RS13245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY144_RS13260	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY144_RS13270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY144_RS13300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_RS13320	COG0848	biopolymer transport protein
FY144_RS13330	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY144_RS13345	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY144_RS13350	COG3454	Phosphonate metabolism
FY144_RS13355	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY144_RS13360	COG3639	organic phosphonate transmembrane transporter activity
FY144_RS13365	COG3639	organic phosphonate transmembrane transporter activity
FY144_RS13370	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FY144_RS13375	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY144_RS13385	COG4778	phosphonate C-P lyase system protein PhnL
FY144_RS13390	COG4107	phosphonate C-P lyase system protein PhnK
FY144_RS13395	COG3627	carbon phosphorus lyase activity
FY144_RS13400	COG3626	phosphonate metabolism
FY144_RS13405	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY144_RS13410	COG3624	Phosphonate C-P lyase system protein PhnG
FY144_RS13415	COG2188	Transcriptional regulator
FY144_RS13420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY144_RS13425	COG0837	glucose binding
FY144_RS13430	COG1803	Methylglyoxal synthase
FY144_RS13435	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY144_RS13440	COG4166	transmembrane transport
FY144_RS13445	COG4174	ABC transporter (Permease)
FY144_RS13450	COG4239	(ABC) transporter, permease
FY144_RS13455	COG4172	Belongs to the ABC transporter superfamily
FY144_RS13460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS13465	COG0174	glutamine synthetase
FY144_RS13470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS13475	COG3265	gluconokinase activity
FY144_RS13480	COG1174	glycine betaine transport
FY144_RS13485	COG1125	glycine betaine transport
FY144_RS13490	COG1174	glycine betaine transport
FY144_RS13495	COG1732	Glycine betaine
FY144_RS13505	COG1959	2 iron, 2 sulfur cluster binding
FY144_RS13510	COG1840	ABC-type Fe3 transport system, periplasmic component
FY144_RS13515	COG0501	Belongs to the peptidase M48B family
FY144_RS13520	COG4269	membrane
FY144_RS13535	COG0697	spore germination
FY144_RS13550	COG0791	NLP P60 protein
FY144_RS13560	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY144_RS13565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY144_RS13600	COG4964	Belongs to the GSP D family
FY144_RS13640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY144_RS13645	COG3422	double-strand break repair
FY144_RS13650	COG3757	hydrolase, family 25
FY144_RS13655	COG0697	spore germination
FY144_RS13660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY144_RS13675	COG0492	ferredoxin-NADP+ reductase activity
FY144_RS13690	COG0481	GTPase activity
FY144_RS13695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY144_RS13710	COG1396	sequence-specific DNA binding
FY144_RS13725	COG1917	Cupin 2, conserved barrel domain protein
FY144_RS13725	COG2169	Transcriptional regulator
FY144_RS13730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY144_RS13755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY144_RS13760	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY144_RS13765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY144_RS13775	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY144_RS13780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY144_RS13780	COG0072	phenylalanine-tRNA ligase activity
FY144_RS13785	COG0667	Aldo Keto reductase
FY144_RS13805	COG4977	sequence-specific DNA binding
FY144_RS13830	COG1570	exodeoxyribonuclease VII activity
FY144_RS13835	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_RS13845	COG1846	Transcriptional regulator
FY144_RS13850	COG0697	spore germination
FY144_RS13855	COG2309	aminopeptidase activity
FY144_RS13865	COG1393	Belongs to the ArsC family
FY144_RS13885	COG1309	transcriptional regulator
FY144_RS13895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY144_RS13895	COG0519	Catalyzes the synthesis of GMP from XMP
FY144_RS13910	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY144_RS13940	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY144_RS13950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY144_RS13960	COG1968	undecaprenyl-diphosphatase activity
FY144_RS13975	COG0284	orotidine-5'-phosphate decarboxylase activity
FY144_RS13985	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY144_RS13995	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY144_RS14000	COG0792	nuclease activity
FY144_RS14015	COG1175	transmembrane transport
FY144_RS14020	COG0395	ABC-type sugar transport system, permease component
FY144_RS14025	COG3842	ATPase activity
FY144_RS14035	COG0189	ligase activity
FY144_RS14040	COG0606	chelatase, subunit chli
FY144_RS14045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY144_RS14050	COG1280	lysine exporter protein (LysE YggA)
FY144_RS14055	COG0756	dUTP diphosphatase activity
FY144_RS14060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY144_RS14065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY144_RS14080	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY144_RS14085	COG2226	methyltransferase
FY144_RS14090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY144_RS14095	COG1024	Enoyl-CoA hydratase
FY144_RS14100	COG0268	Binds directly to 16S ribosomal RNA
FY144_RS14110	COG2161	toxin-antitoxin pair type II binding
FY144_RS14145	COG2267	carboxylic ester hydrolase activity
FY144_RS14190	COG3436	PFAM IS66 Orf2 family protein
FY144_RS14195	COG4372	Transposase
FY144_RS14220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY144_RS14290	COG0668	transmembrane transport
FY144_RS14330	COG3706	GGDEF domain
FY144_RS14355	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_RS14370	COG2358	TRAP transporter, solute receptor (TAXI family
FY144_RS14385	COG1802	Transcriptional regulator
FY144_RS14390	COG3842	ATPase activity
FY144_RS14395	COG4209	transmembrane transport
FY144_RS14400	COG0395	ABC-type sugar transport system, permease component
FY144_RS14405	COG1653	transport
FY144_RS14415	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS14425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY144_RS14435	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_RS14465	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS14470	COG0625	glutathione transferase activity
FY144_RS14490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY144_RS14495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY144_RS14510	COG0534	Mate efflux family protein
FY144_RS14560	COG1278	Cold shock
FY144_RS14585	COG0640	Transcriptional regulator
FY144_RS14610	COG4297	protein containing double-stranded beta helix domain
FY144_RS14620	COG4178	(ABC) transporter
FY144_RS14640	COG0596	Alpha beta hydrolase
FY144_RS14645	COG0583	DNA-binding transcription factor activity
FY144_RS14655	COG0765	amino acid transport
FY144_RS14660	COG1126	abc transporter atp-binding protein
FY144_RS14665	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_RS14670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS14685	COG2375	cellular response to nickel ion
FY144_RS14705	COG1522	sequence-specific DNA binding
FY144_RS14710	COG1012	belongs to the aldehyde dehydrogenase family
FY144_RS14715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY144_RS14720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY144_RS14725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY144_RS14730	COG2423	ornithine cyclodeaminase activity
FY144_RS14735	COG0006	proline dipeptidase activity
FY144_RS14740	COG3608	succinylglutamate desuccinylase aspartoacylase
FY144_RS14745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_RS14750	COG0765	amino acid transport
FY144_RS14755	COG0765	amino acid transport
FY144_RS14760	COG1126	abc transporter atp-binding protein
FY144_RS14770	COG1082	Xylose isomerase domain protein TIM barrel
FY144_RS14775	COG0572	uridine kinase
FY144_RS14785	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS14790	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS14795	COG1129	ABC transporter
FY144_RS14815	COG3284	Transcriptional regulator
FY144_RS14820	COG1063	alcohol dehydrogenase
FY144_RS14830	COG0110	maltose O-acetyltransferase activity
FY144_RS14835	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY144_RS14860	COG0488	(ABC) transporter
FY144_RS14865	COG1132	(ABC) transporter
FY144_RS14870	COG3181	Tripartite tricarboxylate transporter family receptor
FY144_RS14875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY144_RS14885	COG3237	CsbD-like
FY144_RS14910	COG3842	ATPase activity
FY144_RS14920	COG0483	inositol monophosphate 1-phosphatase activity
FY144_RS14930	COG0405	Gamma-glutamyltransferase
FY144_RS14935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS14940	COG0601	transmembrane transport
FY144_RS14945	COG0747	negative chemotaxis
FY144_RS14950	COG2186	Transcriptional regulator
FY144_RS14960	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_RS14965	COG4172	Belongs to the ABC transporter superfamily
FY144_RS14970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS14975	COG0601	transmembrane transport
FY144_RS14980	COG0747	negative chemotaxis
FY144_RS14985	COG2186	Transcriptional regulator
FY144_RS14995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_RS15000	COG2223	nitrite transmembrane transporter activity
FY144_RS15010	COG3383	formate dehydrogenase (NAD+) activity
FY144_RS15035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY144_RS15045	COG0765	amino acid transport
FY144_RS15050	COG0765	amino acid transport
FY144_RS15055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_RS15070	COG3938	Belongs to the proline racemase family
FY144_RS15080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS15090	COG0765	amino acid transport
FY144_RS15110	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY144_RS15115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_RS15125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY144_RS15130	COG0784	Response regulator, receiver
FY144_RS15145	COG0842	Transport permease protein
FY144_RS15150	COG0842	Transport permease protein
FY144_RS15150	COG1129	ABC transporter
FY144_RS15155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_RS15160	COG1486	melibiose metabolic process
FY144_RS15165	COG4172	Belongs to the ABC transporter superfamily
FY144_RS15170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS15175	COG0601	transmembrane transport
FY144_RS15180	COG0747	negative chemotaxis
FY144_RS15185	COG1486	melibiose metabolic process
FY144_RS15210	COG1940	carbohydrate kinase activity
FY144_RS15215	COG2182	Extracellular solute-binding protein
FY144_RS15220	COG1175	transmembrane transport
FY144_RS15225	COG0395	ABC-type sugar transport system, permease component
FY144_RS15230	COG0165	Argininosuccinate lyase
FY144_RS15235	COG3842	ATPase activity
FY144_RS15240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_RS15245	COG3119	arylsulfatase activity
FY144_RS15255	COG0583	DNA-binding transcription factor activity
FY144_RS15260	COG1120	ATPase activity
FY144_RS15265	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_RS15270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_RS15280	COG4774	siderophore transport
FY144_RS15295	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY144_RS15310	COG2205	protein histidine kinase activity
FY144_RS15315	COG0745	RESPONSE REGULATOR receiver
FY144_RS15335	COG1392	Phosphate transport regulator
FY144_RS15340	COG0306	phosphate transporter
FY144_RS15345	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY144_RS15355	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY144_RS15365	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS15370	COG5001	Diguanylate cyclase
FY144_RS15370	COG3300	MHYT domain
FY144_RS15390	COG2186	Transcriptional regulator
FY144_RS15395	COG0601	transmembrane transport
FY144_RS15400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS15420	COG3842	ATPase activity
FY144_RS15425	COG0395	ABC-type sugar transport system, permease component
FY144_RS15440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY144_RS15440	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY144_RS15445	COG1609	Transcriptional regulator
FY144_RS15460	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY144_RS15465	COG1088	dTDP-glucose 4,6-dehydratase activity
FY144_RS15470	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY144_RS15475	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY144_RS15495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY144_RS15525	COG4372	Transposase
FY144_RS15530	COG3436	PFAM IS66 Orf2 family protein
FY144_RS15540	COG2226	methyltransferase
FY144_RS15570	COG4372	Transposase
FY144_RS15575	COG3436	PFAM IS66 Orf2 family protein
FY144_RS15590	COG1132	(ABC) transporter
FY144_RS15620	COG0583	DNA-binding transcription factor activity
FY144_RS15625	COG0667	Aldo Keto reductase
FY144_RS15630	COG0385	Bile acid
FY144_RS15690	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY144_RS15710	COG3842	ATPase activity
FY144_RS15735	COG0300	oxidoreductase activity
FY144_RS15740	COG0584	glycerophosphoryl diester phosphodiesterase
FY144_RS15745	COG1940	carbohydrate kinase activity
FY144_RS15755	COG3712	iron ion homeostasis
FY144_RS15760	COG4774	siderophore transport
FY144_RS15765	COG2814	Major facilitator Superfamily
FY144_RS15785	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY144_RS15800	COG1175	transmembrane transport
FY144_RS15805	COG0395	ABC-type sugar transport system, permease component
FY144_RS15810	COG1609	Transcriptional regulator
FY144_RS15820	COG0673	inositol 2-dehydrogenase activity
FY144_RS15840	COG1609	Transcriptional regulator
FY144_RS15845	COG0183	Belongs to the thiolase family
FY144_RS15850	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY144_RS15860	COG1414	Transcriptional regulator
FY144_RS15875	COG0583	DNA-binding transcription factor activity
FY144_RS15885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY144_RS15890	COG3485	protocatechuate 3,4-dioxygenase
FY144_RS15895	COG3485	protocatechuate 3,4-dioxygenase
FY144_RS15900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY144_RS15905	COG0765	amino acid transport
FY144_RS15910	COG0765	amino acid transport
FY144_RS15915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_RS15920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_RS15925	COG1126	abc transporter atp-binding protein
FY144_RS15930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY144_RS15935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY144_RS15965	COG0747	negative chemotaxis
FY144_RS15975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS15990	COG0683	leucine binding
FY144_RS16005	COG0411	ABC transporter
FY144_RS16020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_RS16025	COG3962	Belongs to the TPP enzyme family
FY144_RS16035	COG3718	enzyme involved in inositol metabolism
FY144_RS16045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY144_RS16050	COG1609	Transcriptional regulator
FY144_RS16055	COG1846	Transcriptional regulator
FY144_RS16065	COG0523	cobalamin synthesis protein
FY144_RS16095	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY144_RS16115	COG0800	Aldolase
FY144_RS16120	COG2954	triphosphatase activity
FY144_RS16130	COG1054	Belongs to the UPF0176 family
FY144_RS16135	COG3300	MHYT domain
FY144_RS16135	COG5001	Diguanylate cyclase
FY144_RS16145	COG2011	ABC-type metal ion transport system permease component
FY144_RS16150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY144_RS16155	COG0778	Nitroreductase
FY144_RS16165	COG2115	Belongs to the xylose isomerase family
FY144_RS16170	COG1070	Carbohydrate kinase
FY144_RS16175	COG1609	Transcriptional regulator
FY144_RS16195	COG1309	transcriptional regulator
FY144_RS16200	COG1253	flavin adenine dinucleotide binding
FY144_RS16205	COG0471	metal ion transport
FY144_RS16205	COG3273	potassium ion transport
FY144_RS16210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY144_RS16215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY144_RS16220	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY144_RS16230	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY144_RS16235	COG1121	(ABC) transporter
FY144_RS16240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY144_RS16245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY144_RS16255	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS16260	COG1414	Transcriptional regulator
FY144_RS16265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY144_RS16285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY144_RS16310	COG1069	ribulokinase activity
FY144_RS16335	COG0395	ABC-type sugar transport system, permease component
FY144_RS16340	COG1175	transmembrane transport
FY144_RS16350	COG2390	Transcriptional regulator
FY144_RS16355	COG4172	Belongs to the ABC transporter superfamily
FY144_RS16360	COG1473	amidohydrolase
FY144_RS16370	COG0601	transmembrane transport
FY144_RS16375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS16385	COG0693	protein deglycase activity
FY144_RS16390	COG0154	amidase activity
FY144_RS16395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS16405	COG0747	negative chemotaxis
FY144_RS16410	COG0583	DNA-binding transcription factor activity
FY144_RS16415	COG4608	Belongs to the ABC transporter superfamily
FY144_RS16420	COG0444	Belongs to the ABC transporter superfamily
FY144_RS16425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS16430	COG0601	transmembrane transport
FY144_RS16435	COG0747	negative chemotaxis
FY144_RS16450	COG1473	amidohydrolase
FY144_RS16455	COG2814	Major facilitator Superfamily
FY144_RS16460	COG0583	DNA-binding transcription factor activity
FY144_RS16465	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY144_RS16475	COG3842	ATPase activity
FY144_RS16485	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY144_RS16495	COG1609	Transcriptional regulator
FY144_RS16500	COG0583	DNA-binding transcription factor activity
FY144_RS16505	COG1960	acyl-CoA dehydrogenase activity
FY144_RS16510	COG1629	transport
FY144_RS16510	COG4774	siderophore transport
FY144_RS16520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS16530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_RS16535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_RS16545	COG2375	cellular response to nickel ion
FY144_RS16555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY144_RS16560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY144_RS16560	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY144_RS16570	COG1169	isochorismate synthase
FY144_RS16575	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY144_RS16580	COG1535	isochorismatase
FY144_RS16580	COG3433	isochorismatase activity
FY144_RS16585	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS16600	COG3005	denitrification pathway
FY144_RS16610	COG0243	molybdopterin cofactor binding
FY144_RS16625	COG4459	periplasmic nitrate reductase
FY144_RS16635	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY144_RS16660	COG0826	peptidase U32
FY144_RS16670	COG3189	MarR family transcriptional regulator
FY144_RS16675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY144_RS16680	COG0163	prenyltransferase activity
FY144_RS16695	COG1845	cytochrome c oxidase, subunit III
FY144_RS16710	COG3256	nitric oxide reductase
FY144_RS16715	COG0714	Associated with various cellular activities
FY144_RS16775	COG0673	inositol 2-dehydrogenase activity
FY144_RS16785	COG1609	Transcriptional regulator
FY144_RS16790	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS16795	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS16800	COG1129	ABC transporter
FY144_RS16805	COG1879	ABC-type sugar transport system periplasmic component
FY144_RS16810	COG3547	Transposase (IS116 IS110 IS902 family)
FY144_RS16820	COG0583	DNA-binding transcription factor activity
FY144_RS16835	COG1609	Transcriptional regulator
FY144_RS16840	COG0673	inositol 2-dehydrogenase activity
FY144_RS16850	COG1653	transport
FY144_RS16855	COG1175	transmembrane transport
FY144_RS16860	COG0395	ABC-type sugar transport system, permease component
FY144_RS16865	COG3842	ATPase activity
FY144_RS16880	COG1253	flavin adenine dinucleotide binding
FY144_RS16905	COG5001	Diguanylate cyclase
FY144_RS16905	COG3300	MHYT domain
FY144_RS17030	COG0477	Major facilitator Superfamily
FY144_RS17050	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS17060	COG1879	ABC-type sugar transport system periplasmic component
FY144_RS17070	COG1063	alcohol dehydrogenase
FY144_RS17085	COG1136	(ABC) transporter
FY144_RS17100	COG1309	transcriptional regulator
FY144_RS17120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY144_RS17130	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY144_RS17130	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY144_RS17145	COG0047	phosphoribosylformylglycinamidine synthase activity
FY144_RS17160	COG1845	cytochrome c oxidase, subunit III
FY144_RS17165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY144_RS17170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY144_RS17175	COG3474	cytochrome
FY144_RS17200	COG3842	ATPase activity
FY144_RS17205	COG0395	ABC-type sugar transport system, permease component
FY144_RS17210	COG1175	transmembrane transport
FY144_RS17215	COG1653	transport
FY144_RS17220	COG1012	belongs to the aldehyde dehydrogenase family
FY144_RS17225	COG1024	Enoyl-CoA hydratase
FY144_RS17245	COG4702	Belongs to the UPF0303 family
FY144_RS17250	COG4774	siderophore transport
FY144_RS17250	COG1629	transport
FY144_RS17255	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY144_RS17260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_RS17265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_RS17270	COG1120	ATPase activity
FY144_RS17285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY144_RS17295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY144_RS17300	COG1177	transmembrane transport
FY144_RS17305	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY144_RS17310	COG3842	ATPase activity
FY144_RS17335	COG1335	isochorismatase
FY144_RS17350	COG0583	DNA-binding transcription factor activity
FY144_RS17355	COG2318	DinB family
FY144_RS17380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY144_RS17410	COG0778	Nitroreductase
FY144_RS17430	COG0277	FAD linked oxidase domain protein
FY144_RS17450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS17455	COG4172	Belongs to the ABC transporter superfamily
FY144_RS17465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS17475	COG0431	NADPH-dependent FMN reductase
FY144_RS17495	COG1522	sequence-specific DNA binding
FY144_RS17500	COG2376	Dihydroxyacetone kinase
FY144_RS17530	COG3609	addiction module antidote protein, CC2985 family
FY144_RS17570	COG0739	heme binding
FY144_RS17570	COG0741	lytic transglycosylase activity
FY144_RS17570	COG1196	nuclear chromosome segregation
FY144_RS17575	COG0542	response to heat
FY144_RS17585	COG2890	protein-(glutamine-N5) methyltransferase activity
FY144_RS17590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY144_RS17600	COG0527	aspartate kinase activity
FY144_RS17615	COG0019	diaminopimelate decarboxylase activity
FY144_RS17630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY144_RS17640	COG3920	Histidine kinase
FY144_RS17650	COG0784	Response regulator, receiver
FY144_RS17665	COG1522	sequence-specific DNA binding
FY144_RS17675	COG1116	anion transmembrane transporter activity
FY144_RS17680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_RS17685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_RS17690	COG1012	belongs to the aldehyde dehydrogenase family
FY144_RS17695	COG0583	DNA-binding transcription factor activity
FY144_RS17700	COG0435	Glutathione S-transferase
FY144_RS17715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY144_RS17720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_RS17725	COG0189	ligase activity
FY144_RS17745	COG0693	protein deglycase activity
FY144_RS17775	COG3685	Protein conserved in bacteria
FY144_RS17780	COG4993	Dehydrogenase
FY144_RS17795	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS17800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY144_RS17845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS17860	COG0246	Mannitol dehydrogenase
FY144_RS17865	COG4608	Belongs to the ABC transporter superfamily
FY144_RS17870	COG0444	Belongs to the ABC transporter superfamily
FY144_RS17875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS17880	COG0601	transmembrane transport
FY144_RS17885	COG0747	negative chemotaxis
FY144_RS17895	COG4221	oxidoreductase activity
FY144_RS17925	COG0539	negative regulation of cytoplasmic translation
FY144_RS17930	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY144_RS17960	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY144_RS17965	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY144_RS17995	COG1294	oxidase, subunit
FY144_RS18005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY144_RS18010	COG4988	ABC transporter
FY144_RS18020	COG1063	alcohol dehydrogenase
FY144_RS18025	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS18030	COG2084	Dehydrogenase
FY144_RS18040	COG1522	sequence-specific DNA binding
FY144_RS18045	COG1794	racemase activity, acting on amino acids and derivatives
FY144_RS18060	COG0058	SHG alpha-glucan phosphorylase activity
FY144_RS18065	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY144_RS18070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY144_RS18075	COG0297	glycogen (starch) synthase activity
FY144_RS18080	COG0033	Phosphoglucomutase
FY144_RS18085	COG1523	belongs to the glycosyl hydrolase 13 family
FY144_RS18105	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY144_RS18105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY144_RS18120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS18125	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY144_RS18145	COG1215	transferase activity, transferring glycosyl groups
FY144_RS18150	COG2327	Polysaccharide pyruvyl transferase
FY144_RS18155	COG0463	Glycosyl transferase, family 2
FY144_RS18160	COG2244	polysaccharide biosynthetic process
FY144_RS18165	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY144_RS18170	COG2273	Hydrolase Family 16
FY144_RS18175	COG0438	transferase activity, transferring glycosyl groups
FY144_RS18180	COG1215	transferase activity, transferring glycosyl groups
FY144_RS18185	COG1215	transferase activity, transferring glycosyl groups
FY144_RS18190	COG1215	transferase activity, transferring glycosyl groups
FY144_RS18195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY144_RS18200	COG0489	protein tyrosine kinase activity
FY144_RS18200	COG3206	protein involved in exopolysaccharide biosynthesis
FY144_RS18205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY144_RS18225	COG4176	ABC-type proline glycine betaine transport system permease component
FY144_RS18230	COG4175	Glycine betaine
FY144_RS18230	COG3448	diguanylate cyclase activity
FY144_RS18245	COG0564	pseudouridine synthase activity
FY144_RS18250	COG0500	methyltransferase
FY144_RS18260	COG2133	pyrroloquinoline quinone binding
FY144_RS18270	COG2197	response regulator
FY144_RS18275	COG4585	Histidine kinase
FY144_RS18280	COG1879	ABC-type sugar transport system periplasmic component
FY144_RS18285	COG1129	ABC transporter
FY144_RS18290	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS18300	COG3386	PFAM SMP-30 Gluconolaconase
FY144_RS18305	COG2137	regulation of response to DNA damage stimulus
FY144_RS18310	COG3474	cytochrome
FY144_RS18320	COG1120	ATPase activity
FY144_RS18335	COG4774	siderophore transport
FY144_RS18340	COG0583	DNA-binding transcription factor activity
FY144_RS18350	COG2194	sulfuric ester hydrolase activity
FY144_RS18365	COG0477	Major facilitator Superfamily
FY144_RS18385	COG0673	inositol 2-dehydrogenase activity
FY144_RS18390	COG0697	spore germination
FY144_RS18400	COG0010	Belongs to the arginase family
FY144_RS18415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY144_RS18420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY144_RS18425	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY144_RS18430	COG0156	8-amino-7-oxononanoate synthase activity
FY144_RS18435	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY144_RS18485	COG0671	phosphoesterase, PA-phosphatase related
FY144_RS18490	COG0745	RESPONSE REGULATOR receiver
FY144_RS18495	COG2205	protein histidine kinase activity
FY144_RS18505	COG0477	Major facilitator Superfamily
FY144_RS18510	COG0583	DNA-binding transcription factor activity
FY144_RS18530	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY144_RS18545	COG0346	lactoylglutathione lyase activity
FY144_RS18550	COG0583	DNA-binding transcription factor activity
FY144_RS18560	COG0840	transmembrane signaling receptor activity
FY144_RS18575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_RS18590	COG2828	Protein conserved in bacteria
FY144_RS18595	COG0583	DNA-binding transcription factor activity
FY144_RS18600	COG1846	Transcriptional regulator
FY144_RS18625	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS18630	COG1309	transcriptional regulator
FY144_RS18635	COG2207	Transcriptional regulator
FY144_RS18655	COG1566	PFAM secretion protein HlyD family protein
FY144_RS18675	COG0395	ABC-type sugar transport system, permease component
FY144_RS18680	COG4166	transmembrane transport
FY144_RS18685	COG0601	transmembrane transport
FY144_RS18690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS18695	COG4172	Belongs to the ABC transporter superfamily
FY144_RS18735	COG0402	S-adenosylhomocysteine deaminase activity
FY144_RS18740	COG1228	amidohydrolase
FY144_RS18745	COG2986	histidine ammonia-lyase
FY144_RS18755	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY144_RS18785	COG1192	Involved in chromosome partitioning
FY144_RS18790	COG1475	DNA binding
FY144_RS18795	COG1414	Transcriptional regulator
FY144_RS18815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY144_RS18820	COG4771	TonB-dependent receptor
FY144_RS18830	COG0366	Alpha amylase catalytic
FY144_RS18835	COG4770	biotin carboxylase activity
FY144_RS18840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY144_RS18845	COG4336	lyase activity
FY144_RS18850	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY144_RS18855	COG1914	H( )-stimulated, divalent metal cation uptake system
FY144_RS18860	COG1802	Transcriptional regulator
FY144_RS18865	COG3707	response regulator
FY144_RS18875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_RS18880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_RS18885	COG1116	anion transmembrane transporter activity
FY144_RS18890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY144_RS18900	COG0243	molybdopterin cofactor binding
FY144_RS18905	COG1648	precorrin-2 dehydrogenase activity
FY144_RS18905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY144_RS18920	COG3842	ATPase activity
FY144_RS18935	COG0395	ABC-type sugar transport system, permease component
FY144_RS18950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY144_RS18965	COG0071	Belongs to the small heat shock protein (HSP20) family
FY144_RS19000	COG1879	ABC-type sugar transport system periplasmic component
FY144_RS19005	COG1129	ABC transporter
FY144_RS19010	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS19020	COG0667	Aldo Keto reductase
FY144_RS19025	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY144_RS19030	COG1830	Aldolase
FY144_RS19035	COG1070	Carbohydrate kinase
FY144_RS19040	COG0840	transmembrane signaling receptor activity
FY144_RS19055	COG0436	Aminotransferase
FY144_RS19065	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY144_RS19075	COG3842	ATPase activity
FY144_RS19080	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY144_RS19085	COG1984	allophanate hydrolase subunit 2
FY144_RS19090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY144_RS19100	COG0439	Biotin carboxylase
FY144_RS19105	COG0511	ligase activity, forming carbon-carbon bonds
FY144_RS19110	COG0697	spore germination
FY144_RS19115	COG0697	spore germination
FY144_RS19130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY144_RS19145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_RS19150	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS19155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY144_RS19160	COG4221	oxidoreductase activity
FY144_RS19165	COG0765	amino acid transport
FY144_RS19170	COG0765	amino acid transport
FY144_RS19180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_RS19185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY144_RS19190	COG1063	alcohol dehydrogenase
FY144_RS19205	COG1304	FMN binding
FY144_RS19230	COG3842	ATPase activity
FY144_RS19240	COG0395	ABC-type sugar transport system, permease component
FY144_RS19245	COG1175	transmembrane transport
FY144_RS19260	COG2186	Transcriptional regulator
FY144_RS19265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY144_RS19270	COG0488	(ABC) transporter
FY144_RS19285	COG2307	Protein conserved in bacteria
FY144_RS19285	COG2308	Evidence 4 Homologs of previously reported genes of
FY144_RS19325	COG1454	alcohol dehydrogenase
FY144_RS19330	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY144_RS19340	COG0747	negative chemotaxis
FY144_RS19345	COG0601	transmembrane transport
FY144_RS19350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS19355	COG4172	Belongs to the ABC transporter superfamily
FY144_RS19360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_RS19380	COG2986	histidine ammonia-lyase
FY144_RS19385	COG0517	IMP dehydrogenase activity
FY144_RS19385	COG4175	Glycine betaine
FY144_RS19390	COG4176	ABC-type proline glycine betaine transport system permease component
FY144_RS19410	COG1309	transcriptional regulator
FY144_RS19430	COG2186	Transcriptional regulator
FY144_RS19435	COG1027	Aspartate ammonia-lyase
FY144_RS19445	COG0252	asparaginase activity
FY144_RS19455	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY144_RS19465	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY144_RS19470	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY144_RS19475	COG2205	protein histidine kinase activity
FY144_RS19490	COG0070	glutamate synthase
FY144_RS19490	COG0069	glutamate synthase activity
FY144_RS19490	COG0067	glutamate synthase
FY144_RS19505	COG2205	protein histidine kinase activity
FY144_RS19520	COG2951	lytic endotransglycosylase activity
FY144_RS19525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY144_RS19555	COG0330	HflC and HflK could
FY144_RS19560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY144_RS19565	COG0737	Belongs to the 5'-nucleotidase family
FY144_RS19575	COG5310	Homospermidine synthase
FY144_RS19585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY144_RS19590	COG1164	Oligoendopeptidase f
FY144_RS19595	COG2204	response regulator
FY144_RS19600	COG3108	Peptidase M15
FY144_RS19605	COG0469	pyruvate kinase activity
FY144_RS19625	COG3750	Belongs to the UPF0335 family
FY144_RS19630	COG0457	Tetratricopeptide repeat
FY144_RS19635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY144_RS19640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY144_RS19675	COG0483	inositol monophosphate 1-phosphatase activity
FY144_RS19695	COG1132	(ABC) transporter
FY144_RS19700	COG0254	rRNA binding
FY144_RS19725	COG3588	fructose-bisphosphate aldolase
FY144_RS19730	COG0126	phosphoglycerate kinase activity
FY144_RS19735	COG3263	regulation of cellular component size
FY144_RS19770	COG1253	flavin adenine dinucleotide binding
FY144_RS19780	COG1692	metallophosphoesterase
FY144_RS19795	COG0217	transcriptional regulatory protein
FY144_RS19800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS19805	COG0840	transmembrane signaling receptor activity
FY144_RS19810	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY144_RS19815	COG0632	four-way junction helicase activity
FY144_RS19820	COG2255	four-way junction helicase activity
FY144_RS19835	COG0494	nUDIX hydrolase
FY144_RS19845	COG0824	Thioesterase
FY144_RS19865	COG0823	Involved in the tonB-independent uptake of proteins
FY144_RS19870	COG2885	chlorophyll binding
FY144_RS19880	COG0037	tRNA processing
FY144_RS19885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY144_RS19890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY144_RS19905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY144_RS19920	COG0482	sulfurtransferase activity
FY144_RS19955	COG2835	tetraacyldisaccharide 4'-kinase activity
FY144_RS19960	COG2373	Large extracellular alpha-helical protein
FY144_RS19965	COG4953	penicillin-binding protein 1C
FY144_RS19975	COG1473	amidohydrolase
FY144_RS19980	COG1686	Belongs to the peptidase S11 family
FY144_RS19985	COG0523	cobalamin synthesis protein
FY144_RS19990	COG0425	Belongs to the sulfur carrier protein TusA family
FY144_RS19990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY144_RS19995	COG3034	peptidoglycan biosynthetic process
FY144_RS20000	COG0825	malonyl-CoA metabolic process
FY144_RS20005	COG4974	Belongs to the 'phage' integrase family
FY144_RS20015	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY144_RS20020	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY144_RS20060	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY144_RS20065	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY144_RS20085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY144_RS20090	COG2226	methyltransferase
FY144_RS20095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY144_RS20100	COG0287	Prephenate dehydrogenase
FY144_RS20110	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY144_RS20130	COG2884	Cell division ATP-binding protein ftsE
FY144_RS20165	COG0165	Argininosuccinate lyase
FY144_RS20170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY144_RS20180	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY144_RS20190	COG2086	electron transfer activity
FY144_RS20200	COG2096	Adenosyltransferase
FY144_RS20210	COG0300	oxidoreductase activity
FY144_RS20220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY144_RS20230	COG1396	sequence-specific DNA binding
FY144_RS20230	COG3800	Transcriptional regulator
FY144_RS20235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY144_RS20240	COG0625	glutathione transferase activity
FY144_RS20255	COG4770	biotin carboxylase activity
FY144_RS20260	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY144_RS20260	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY144_RS20265	COG0346	lactoylglutathione lyase activity
FY144_RS20280	COG4213	ABC transporter substrate-binding protein
FY144_RS20285	COG4214	carbohydrate transport
FY144_RS20290	COG1129	ABC transporter
FY144_RS20295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY144_RS20305	COG1396	sequence-specific DNA binding
FY144_RS20360	COG3833	ABC-type maltose transport systems, permease component
FY144_RS20365	COG3842	ATPase activity
FY144_RS20380	COG2273	Hydrolase Family 16
FY144_RS20380	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY144_RS20385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY144_RS20400	COG0438	transferase activity, transferring glycosyl groups
FY144_RS20405	COG0438	transferase activity, transferring glycosyl groups
FY144_RS20425	COG0489	protein tyrosine kinase activity
FY144_RS20425	COG3206	protein involved in exopolysaccharide biosynthesis
FY144_RS20435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY144_RS20450	COG2244	polysaccharide biosynthetic process
FY144_RS20515	COG0697	spore germination
FY144_RS20520	COG0653	protein targeting
FY144_RS20525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY144_RS20530	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY144_RS20540	COG0494	nUDIX hydrolase
FY144_RS20555	COG2226	methyltransferase
FY144_RS20560	COG1040	competence protein
FY144_RS20570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY144_RS20580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY144_RS20595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY144_RS20600	COG4150	thiosulfate binding
FY144_RS20610	COG4208	sulfate ABC transporter
FY144_RS20615	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY144_RS20620	COG4335	DNA alkylation repair
FY144_RS20635	COG5001	Diguanylate cyclase
FY144_RS20640	COG2264	protein methyltransferase activity
FY144_RS20655	COG3254	rhamnose metabolic process
FY144_RS20660	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS20665	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS20670	COG1129	ABC transporter
FY144_RS20680	COG1349	DNA-binding transcription factor activity
FY144_RS20685	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS20685	COG3347	Dehydrogenase
FY144_RS20690	COG4952	isomerase
FY144_RS20695	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY144_RS20700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY144_RS20720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY144_RS20725	COG1960	acyl-CoA dehydrogenase activity
FY144_RS20735	COG0183	Belongs to the thiolase family
FY144_RS20740	COG1960	acyl-CoA dehydrogenase activity
FY144_RS20750	COG0022	dehydrogenase e1 component
FY144_RS20760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY144_RS20765	COG2391	methyltransferase activity
FY144_RS20775	COG0640	Transcriptional regulator
FY144_RS20780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY144_RS20780	COG3453	Protein conserved in bacteria
FY144_RS20790	COG0300	oxidoreductase activity
FY144_RS20805	COG2186	Transcriptional regulator
FY144_RS20815	COG0601	transmembrane transport
FY144_RS20825	COG0444	Belongs to the ABC transporter superfamily
FY144_RS20830	COG4608	Belongs to the ABC transporter superfamily
FY144_RS20850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS20855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS20870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS20875	COG1473	amidohydrolase
FY144_RS20880	COG0747	negative chemotaxis
FY144_RS20895	COG4166	transmembrane transport
FY144_RS20900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS20905	COG0583	DNA-binding transcription factor activity
FY144_RS20915	COG0667	Aldo Keto reductase
FY144_RS20925	COG0444	Belongs to the ABC transporter superfamily
FY144_RS20940	COG0747	negative chemotaxis
FY144_RS20950	COG1960	acyl-CoA dehydrogenase activity
FY144_RS20980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS20985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY144_RS20995	COG1959	2 iron, 2 sulfur cluster binding
FY144_RS21000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS21005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS21010	COG1473	amidohydrolase
FY144_RS21025	COG1126	abc transporter atp-binding protein
FY144_RS21030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_RS21040	COG0583	DNA-binding transcription factor activity
FY144_RS21065	COG1522	sequence-specific DNA binding
FY144_RS21070	COG4172	Belongs to the ABC transporter superfamily
FY144_RS21075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS21110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS21115	COG1012	belongs to the aldehyde dehydrogenase family
FY144_RS21120	COG0473	3-isopropylmalate dehydrogenase activity
FY144_RS21125	COG1012	belongs to the aldehyde dehydrogenase family
FY144_RS21170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_RS21175	COG1120	ATPase activity
FY144_RS21185	COG2226	methyltransferase
FY144_RS21200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_RS21205	COG1120	ATPase activity
FY144_RS21210	COG1595	DNA-templated transcription, initiation
FY144_RS21230	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY144_RS21235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_RS21255	COG0673	inositol 2-dehydrogenase activity
FY144_RS21260	COG0673	inositol 2-dehydrogenase activity
FY144_RS21270	COG1175	transmembrane transport
FY144_RS21275	COG0395	ABC-type sugar transport system, permease component
FY144_RS21280	COG3842	ATPase activity
FY144_RS21290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_RS21295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY144_RS21300	COG2197	response regulator
FY144_RS21305	COG0601	transmembrane transport
FY144_RS21310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS21330	COG0747	negative chemotaxis
FY144_RS21345	COG1446	asparaginase
FY144_RS21350	COG0583	DNA-binding transcription factor activity
FY144_RS21355	COG0601	transmembrane transport
FY144_RS21360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS21375	COG0747	negative chemotaxis
FY144_RS21380	COG1473	amidohydrolase
FY144_RS21395	COG1129	ABC transporter
FY144_RS21400	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS21405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY144_RS21410	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY144_RS21420	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY144_RS21435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS21445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS21450	COG2079	MmgE PrpD family protein
FY144_RS21455	COG1126	abc transporter atp-binding protein
FY144_RS21460	COG0765	amino acid transport
FY144_RS21475	COG0280	phosphate acetyltransferase
FY144_RS21475	COG0281	malic enzyme
FY144_RS21480	COG0583	DNA-binding transcription factor activity
FY144_RS21505	COG1175	transmembrane transport
FY144_RS21510	COG0395	ABC-type sugar transport system, permease component
FY144_RS21525	COG0673	inositol 2-dehydrogenase activity
FY144_RS21535	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY144_RS21540	COG0720	synthase
FY144_RS21545	COG0602	queuosine metabolic process
FY144_RS21550	COG0673	inositol 2-dehydrogenase activity
FY144_RS21560	COG3842	ATPase activity
FY144_RS21575	COG1653	transport
FY144_RS21580	COG1609	Transcriptional regulator
FY144_RS21595	COG2094	Belongs to the DNA glycosylase MPG family
FY144_RS21605	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS21615	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_RS21620	COG0840	transmembrane signaling receptor activity
FY144_RS21625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY144_RS21635	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY144_RS21640	COG1596	polysaccharide export
FY144_RS21645	COG3307	-O-antigen
FY144_RS21675	COG2197	response regulator
FY144_RS21685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_RS21710	COG2942	2-epimerase
FY144_RS21720	COG1215	transferase activity, transferring glycosyl groups
FY144_RS21740	COG1473	amidohydrolase
FY144_RS21750	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS21755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY144_RS21760	COG1301	dicarboxylic acid transport
FY144_RS21765	COG4191	Histidine kinase
FY144_RS21770	COG2204	response regulator
FY144_RS21785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS21790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY144_RS21795	COG1522	sequence-specific DNA binding
FY144_RS21800	COG0351	phosphomethylpyrimidine kinase
FY144_RS21805	COG0352	thiamine-phosphate diphosphorylase activity
FY144_RS21810	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY144_RS21815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_RS21820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_RS21830	COG1501	Belongs to the glycosyl hydrolase 31 family
FY144_RS21835	COG0395	ABC-type sugar transport system, permease component
FY144_RS21840	COG1175	transmembrane transport
FY144_RS21845	COG1653	transport
FY144_RS21850	COG3842	ATPase activity
FY144_RS21865	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FY144_RS21875	COG2188	Transcriptional regulator
FY144_RS21885	COG4989	oxidoreductase activity
FY144_RS21925	COG0438	transferase activity, transferring glycosyl groups
FY144_RS21930	COG0747	negative chemotaxis
FY144_RS21935	COG0601	transmembrane transport
FY144_RS21945	COG3964	amidohydrolase
FY144_RS21960	COG1921	L-seryl-tRNASec selenium transferase activity
FY144_RS21965	COG4172	Belongs to the ABC transporter superfamily
FY144_RS21970	COG0625	glutathione transferase activity
FY144_RS21985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS21990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY144_RS21990	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY144_RS21995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_RS22015	COG1312	Catalyzes the dehydration of D-mannonate
FY144_RS22020	COG1063	alcohol dehydrogenase
FY144_RS22025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY144_RS22035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_RS22040	COG2186	Transcriptional regulator
FY144_RS22045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY144_RS22050	COG0850	regulation of cytokinetic process
FY144_RS22055	COG2894	cell division
FY144_RS22060	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY144_RS22075	COG5001	Diguanylate cyclase
FY144_RS22090	COG0673	inositol 2-dehydrogenase activity
FY144_RS22100	COG1653	transport
FY144_RS22105	COG1175	transmembrane transport
FY144_RS22110	COG0395	ABC-type sugar transport system, permease component
FY144_RS22115	COG3842	ATPase activity
FY144_RS22125	COG0673	inositol 2-dehydrogenase activity
FY144_RS22155	COG0587	DNA-directed DNA polymerase activity
FY144_RS22160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY144_RS22175	COG2186	Transcriptional regulator
FY144_RS22180	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS22185	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS22190	COG1129	ABC transporter
FY144_RS22195	COG1879	ABC-type sugar transport system periplasmic component
FY144_RS22200	COG0129	dihydroxy-acid dehydratase activity
FY144_RS22210	COG0346	lactoylglutathione lyase activity
FY144_RS22225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY144_RS22230	COG4608	Belongs to the ABC transporter superfamily
FY144_RS22240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS22245	COG0601	transmembrane transport
FY144_RS22250	COG0747	negative chemotaxis
FY144_RS22260	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY144_RS22265	COG5001	Diguanylate cyclase
FY144_RS22275	COG3257	ureidoglycine aminohydrolase activity
FY144_RS22285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_RS22290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY144_RS22300	COG1129	ABC transporter
FY144_RS22305	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS22310	COG1879	ABC-type sugar transport system periplasmic component
FY144_RS22315	COG0583	DNA-binding transcription factor activity
FY144_RS22340	COG3047	cAMP biosynthetic process
FY144_RS22350	COG3842	ATPase activity
FY144_RS22355	COG0395	ABC-type sugar transport system, permease component
FY144_RS22360	COG1175	transmembrane transport
FY144_RS22365	COG1653	transport
FY144_RS22370	COG0523	cobalamin synthesis protein
FY144_RS22385	COG0523	cobalamin synthesis protein
FY144_RS22390	COG1121	(ABC) transporter
FY144_RS22400	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY144_RS22415	COG0626	cystathionine gamma-synthase activity
FY144_RS22420	COG2182	Extracellular solute-binding protein
FY144_RS22425	COG1175	transmembrane transport
FY144_RS22430	COG0395	ABC-type sugar transport system, permease component
FY144_RS22445	COG0395	ABC-type sugar transport system, permease component
FY144_RS22450	COG1175	transmembrane transport
FY144_RS22455	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY144_RS22460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_RS22470	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS22475	COG1063	alcohol dehydrogenase
FY144_RS22480	COG1609	Transcriptional regulator
FY144_RS22495	COG2084	Dehydrogenase
FY144_RS22500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_RS22510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY144_RS22515	COG0583	DNA-binding transcription factor activity
FY144_RS22520	COG2223	nitrite transmembrane transporter activity
FY144_RS22525	COG4977	sequence-specific DNA binding
FY144_RS22555	COG0667	Aldo Keto reductase
FY144_RS22570	COG2186	Transcriptional regulator
FY144_RS22575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_RS22580	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY144_RS22585	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS22590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_RS22595	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_RS22600	COG3618	amidohydrolase
FY144_RS22605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_RS22625	COG1175	transmembrane transport
FY144_RS22630	COG0395	ABC-type sugar transport system, permease component
FY144_RS22635	COG3842	ATPase activity
FY144_RS22650	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY144_RS22655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY144_RS22680	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY144_RS22690	COG1278	Cold shock
FY144_RS22700	COG0673	inositol 2-dehydrogenase activity
FY144_RS22715	COG0673	inositol 2-dehydrogenase activity
FY144_RS22720	COG1309	transcriptional regulator
FY144_RS22725	COG1653	transport
FY144_RS22730	COG1175	transmembrane transport
FY144_RS22735	COG0395	ABC-type sugar transport system, permease component
FY144_RS22740	COG3842	ATPase activity
FY144_RS22755	COG1082	Xylose isomerase domain protein TIM barrel
FY144_RS22770	COG1609	Transcriptional regulator
FY144_RS22800	COG1175	transmembrane transport
FY144_RS22805	COG0395	ABC-type sugar transport system, permease component
FY144_RS22810	COG1116	anion transmembrane transporter activity
FY144_RS22815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_RS22820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_RS22830	COG3842	ATPase activity
FY144_RS22835	COG0395	ABC-type sugar transport system, permease component
FY144_RS22845	COG1653	transport
FY144_RS22880	COG3842	ATPase activity
FY144_RS22890	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY144_RS22895	COG0395	ABC-type sugar transport system, permease component
FY144_RS22950	COG2233	PERMEase
FY144_RS22960	COG0702	epimerase
FY144_RS22970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY144_RS22975	COG1522	sequence-specific DNA binding
FY144_RS22995	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS23010	COG1414	Transcriptional regulator
FY144_RS23020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_RS23050	COG4566	intracellular signal transduction
FY144_RS23055	COG4566	intracellular signal transduction
FY144_RS23065	COG0243	molybdopterin cofactor binding
FY144_RS23070	COG0783	Belongs to the Dps family
FY144_RS23090	COG0596	Alpha beta hydrolase
FY144_RS23100	COG1764	response to oxidative stress
FY144_RS23115	COG0596	Alpha beta hydrolase
FY144_RS23150	COG4172	Belongs to the ABC transporter superfamily
FY144_RS23170	COG0747	negative chemotaxis
FY144_RS23180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS23185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_RS23200	COG4106	trans-aconitate 2-methyltransferase activity
FY144_RS23205	COG0025	NhaP-type Na H and K H
FY144_RS23210	COG4302	ethanolamine ammonia-lyase activity
FY144_RS23235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY144_RS23240	COG1349	DNA-binding transcription factor activity
FY144_RS23245	COG4608	Belongs to the ABC transporter superfamily
FY144_RS23255	COG0601	transmembrane transport
FY144_RS23260	COG0747	negative chemotaxis
FY144_RS23265	COG1454	alcohol dehydrogenase
FY144_RS23270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY144_RS23275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY144_RS23330	COG0668	transmembrane transport
FY144_RS23345	COG1566	PFAM secretion protein HlyD family protein
FY144_RS23365	COG1309	transcriptional regulator
FY144_RS23390	COG3422	double-strand break repair
FY144_RS23455	COG3727	T/G mismatch-specific endonuclease activity
FY144_RS23595	COG1192	Involved in chromosome partitioning
FY144_RS23600	COG1475	DNA binding
FY144_RS23605	COG0640	Transcriptional regulator
FY144_RS23620	COG0583	DNA-binding transcription factor activity
FY144_RS23625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY144_RS23670	COG1126	abc transporter atp-binding protein
FY144_RS23680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_RS23685	COG1609	Transcriptional regulator
FY144_RS23750	COG0210	DNA helicase
FY144_RS23810	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY144_RS23810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY144_RS23890	COG1216	Glycosyl transferase, family 2
FY144_RS23910	COG3916	Acyl-homoserine-lactone synthase
FY144_RS23915	COG2197	response regulator
FY144_RS23920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FY144_RS23925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY144_RS23945	COG0840	transmembrane signaling receptor activity
FY144_RS23960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY144_RS23985	COG3842	ATPase activity
FY144_RS23995	COG2390	Transcriptional regulator
FY144_RS24020	COG3177	Filamentation induced by cAMP protein fic
FY144_RS24085	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS24095	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS24105	COG1733	regulation of RNA biosynthetic process
FY144_RS24110	COG1733	regulation of RNA biosynthetic process
FY144_RS24145	COG3547	Transposase (IS116 IS110 IS902 family)
FY144_RS24160	COG3620	sequence-specific DNA binding
FY144_RS24165	COG3550	peptidyl-serine autophosphorylation
FY144_RS24210	COG0459	protein refolding
FY144_RS24215	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY144_RS24245	COG3158	transport of potassium into the cell
FY144_RS24255	COG0583	DNA-binding transcription factor activity
FY144_RS24260	COG0667	Aldo Keto reductase
FY144_RS24275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS24280	COG0601	transmembrane transport
FY144_RS24290	COG1802	Transcriptional regulator
FY144_RS24300	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_RS24305	COG4691	Plasmid stability protein
FY144_RS24310	COG1487	ribonuclease activity
FY144_RS24315	COG2186	Transcriptional regulator
FY144_RS24325	COG1126	abc transporter atp-binding protein
FY144_RS24335	COG0765	amino acid transport
FY144_RS24340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_RS24355	COG0436	Aminotransferase
FY144_RS24360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_RS24405	COG2207	Transcriptional regulator
FY144_RS24425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY144_RS24430	COG1012	belongs to the aldehyde dehydrogenase family
FY144_RS24435	COG1522	sequence-specific DNA binding
FY144_RS24440	COG0747	negative chemotaxis
FY144_RS24445	COG0601	transmembrane transport
FY144_RS24450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS24455	COG4172	Belongs to the ABC transporter superfamily
FY144_RS24465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY144_RS24500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY144_RS24500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FY144_RS24515	COG0642	Histidine kinase
FY144_RS24520	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_RS24540	COG1309	transcriptional regulator
FY144_RS24555	COG2020	methyltransferase activity
FY144_RS24570	COG5489	Protein of unknown function (DUF736)
FY144_RS24580	COG4974	Belongs to the 'phage' integrase family
FY144_RS24585	COG0582	viral genome integration into host DNA
FY144_RS24590	COG4974	Belongs to the 'phage' integrase family
FY144_RS24595	COG5489	Protein of unknown function (DUF736)
FY144_RS24620	COG3838	Conjugal transfer protein Trbc
FY144_RS24625	COG3702	type iv secretory pathway
FY144_RS24630	COG3451	type IV secretory pathway VirB4
FY144_RS24645	COG3704	protein secretion by the type IV secretion system
FY144_RS24655	COG3736	Type IV secretory pathway, component VirB8
FY144_RS24660	COG3504	Conjugal transfer protein
FY144_RS24665	COG2948	multi-organism process
FY144_RS24670	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY144_RS24680	COG0776	regulation of translation
FY144_RS24690	COG3505	Type IV secretory pathway VirD4
FY144_RS24730	COG0583	DNA-binding transcription factor activity
FY144_RS24740	COG1609	Transcriptional regulator
FY144_RS24780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY144_RS24785	COG2010	Cytochrome c
FY144_RS24785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY144_RS24800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY144_RS24825	COG3734	2-keto-3-deoxy-galactonokinase
FY144_RS24830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_RS24835	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_RS24845	COG1175	transmembrane transport
FY144_RS24850	COG0395	ABC-type sugar transport system, permease component
FY144_RS24855	COG3842	ATPase activity
FY144_RS24860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY144_RS24865	COG1414	Transcriptional regulator
FY144_RS24870	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS24875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY144_RS24885	COG3920	Histidine kinase
FY144_RS24915	COG2354	Protein conserved in bacteria
FY144_RS24920	COG0598	Magnesium transport protein CorA
FY144_RS24925	COG1278	Cold shock
FY144_RS24950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY144_RS24955	COG2826	transposase and inactivated derivatives, IS30 family
FY144_RS24970	COG3177	Filamentation induced by cAMP protein fic
FY144_RS24985	COG0071	Belongs to the small heat shock protein (HSP20) family
FY144_RS25000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY144_RS25005	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY144_RS25025	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FY144_RS25035	COG1247	-acetyltransferase
FY144_RS25040	COG1396	sequence-specific DNA binding
FY144_RS25060	COG0583	DNA-binding transcription factor activity
FY144_RS25115	COG1573	uracil-dna glycosylase
FY144_RS25170	COG3685	Protein conserved in bacteria
FY144_RS25175	COG0753	catalase activity
FY144_RS25215	COG0798	PFAM Bile acid sodium symporter
FY144_RS25230	COG0640	Transcriptional regulator
FY144_RS25245	COG1942	4-Oxalocrotonate Tautomerase
FY144_RS25255	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY144_RS25270	COG4585	Histidine kinase
FY144_RS25275	COG2197	response regulator
FY144_RS25295	COG0583	DNA-binding transcription factor activity
FY144_RS25300	COG1741	Belongs to the pirin family
FY144_RS25315	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS25325	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS25335	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS25340	COG4221	oxidoreductase activity
FY144_RS25360	COG4221	oxidoreductase activity
FY144_RS25470	COG1929	Belongs to the glycerate kinase type-1 family
FY144_RS25490	COG0300	oxidoreductase activity
FY144_RS25500	COG0583	DNA-binding transcription factor activity
FY144_RS25515	COG2207	Transcriptional regulator
FY144_RS25520	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS25530	COG1335	isochorismatase
FY144_RS25540	COG0667	Aldo Keto reductase
FY144_RS25545	COG2267	carboxylic ester hydrolase activity
FY144_RS25555	COG0604	alcohol dehydrogenase
FY144_RS25560	COG1902	pentaerythritol trinitrate reductase activity
FY144_RS25565	COG0300	oxidoreductase activity
FY144_RS25570	COG1309	transcriptional regulator
FY144_RS25575	COG2207	Transcriptional regulator
FY144_RS25600	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY144_RS25610	COG1846	Transcriptional regulator
FY144_RS25615	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS25625	COG0583	DNA-binding transcription factor activity
FY144_RS25680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY144_RS25690	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS25700	COG0395	ABC-type sugar transport system, permease component
FY144_RS25725	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS25730	COG1349	DNA-binding transcription factor activity
FY144_RS25735	COG1069	ribulokinase activity
FY144_RS25755	COG1846	Transcriptional regulator
FY144_RS25755	COG1940	carbohydrate kinase activity
FY144_RS25760	COG0534	Mate efflux family protein
FY144_RS25820	COG1278	Cold shock
FY144_RS25830	COG1597	lipid kinase activity
FY144_RS25830	COG1803	Methylglyoxal synthase
FY144_RS25835	COG1522	sequence-specific DNA binding
FY144_RS25850	COG2814	Major facilitator Superfamily
FY144_RS25865	COG1846	Transcriptional regulator
FY144_RS25870	COG2807	transmembrane transport
FY144_RS25875	COG2211	Major facilitator Superfamily
FY144_RS25900	COG2814	Major facilitator Superfamily
FY144_RS25905	COG1846	Transcriptional regulator
FY144_RS25960	COG5002	protein histidine kinase activity
FY144_RS26010	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY144_RS26015	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS26020	COG1129	ABC transporter
FY144_RS26030	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS26035	COG3959	Transketolase, thiamine diphosphate binding domain
FY144_RS26040	COG3958	Transketolase
FY144_RS26045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY144_RS26050	COG2390	Transcriptional regulator
FY144_RS26060	COG4977	sequence-specific DNA binding
FY144_RS26070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FY144_RS26110	COG5001	Diguanylate cyclase
FY144_RS26110	COG3300	MHYT domain
FY144_RS26145	COG2084	Dehydrogenase
FY144_RS26150	COG3622	Belongs to the hyi family
FY144_RS26160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS26165	COG0601	transmembrane transport
FY144_RS26175	COG0747	negative chemotaxis
FY144_RS26180	COG1609	Transcriptional regulator
FY144_RS26185	COG3239	Fatty acid desaturase
FY144_RS26190	COG3706	GGDEF domain
FY144_RS26220	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FY144_RS26225	COG3920	Histidine kinase
FY144_RS26225	COG2202	Pas domain
FY144_RS26240	COG0577	efflux transmembrane transporter activity
FY144_RS26240	COG1136	(ABC) transporter
FY144_RS26245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_RS26255	COG0745	RESPONSE REGULATOR receiver
FY144_RS26300	COG2207	Transcriptional regulator
FY144_RS26310	COG0583	DNA-binding transcription factor activity
FY144_RS26330	COG0583	DNA-binding transcription factor activity
FY144_RS26345	COG1192	Involved in chromosome partitioning
FY144_RS26350	COG1475	DNA binding
FY144_RS26355	COG0640	Transcriptional regulator
FY144_RS26360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY144_RS26405	COG0583	DNA-binding transcription factor activity
FY144_RS26415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_RS26420	COG1116	anion transmembrane transporter activity
FY144_RS26425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_RS26435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS26440	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_RS26470	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_RS26475	COG1129	ABC transporter
FY144_RS26500	COG4172	Belongs to the ABC transporter superfamily
FY144_RS26505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS26510	COG0601	transmembrane transport
FY144_RS26520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS26525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS26530	COG0583	DNA-binding transcription factor activity
FY144_RS26540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY144_RS26550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_RS26555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_RS26560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_RS26645	COG1475	DNA binding
FY144_RS26665	COG2824	Alkylphosphonate utilization operon protein PhnA
FY144_RS26690	COG5489	Protein of unknown function (DUF736)
FY144_RS26715	COG0494	nUDIX hydrolase
FY144_RS26725	COG5489	Protein of unknown function (DUF736)
FY144_RS26815	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY144_RS26830	COG0747	negative chemotaxis
FY144_RS26850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_RS26855	COG0584	glycerophosphoryl diester phosphodiesterase
FY144_RS26860	COG0483	inositol monophosphate 1-phosphatase activity
FY144_RS26925	COG3161	chorismate lyase activity
FY144_RS27210	COG0145	ligase activity
FY144_RS27220	COG0583	DNA-binding transcription factor activity
FY144_RS27270	COG3701	Conjugal transfer protein
FY144_RS27275	COG3846	protein secretion by the type IV secretion system
FY144_RS27285	COG5314	conjugation
FY144_RS27290	COG3451	type IV secretory pathway VirB4
FY144_RS27305	COG4962	Type ii secretion system protein e