locus-tag	class	description
FY149_RS00010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FY149_RS00040	COG1278	Cold shock
FY149_RS00075	COG0411	ABC transporter
FY149_RS00080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY149_RS00085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY149_RS00090	COG1454	alcohol dehydrogenase
FY149_RS00095	COG0747	negative chemotaxis
FY149_RS00100	COG0601	transmembrane transport
FY149_RS00110	COG4608	Belongs to the ABC transporter superfamily
FY149_RS00115	COG1349	DNA-binding transcription factor activity
FY149_RS00120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY149_RS00145	COG4302	ethanolamine ammonia-lyase activity
FY149_RS00150	COG0025	NhaP-type Na H and K H
FY149_RS00155	COG4106	trans-aconitate 2-methyltransferase activity
FY149_RS00165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS00170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS00175	COG0601	transmembrane transport
FY149_RS00200	COG4172	Belongs to the ABC transporter superfamily
FY149_RS00235	COG0596	Alpha beta hydrolase
FY149_RS00250	COG1764	response to oxidative stress
FY149_RS00260	COG0596	Alpha beta hydrolase
FY149_RS00280	COG0783	Belongs to the Dps family
FY149_RS00285	COG0243	molybdopterin cofactor binding
FY149_RS00295	COG4566	intracellular signal transduction
FY149_RS00300	COG4566	intracellular signal transduction
FY149_RS00330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY149_RS00340	COG1414	Transcriptional regulator
FY149_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS00375	COG1522	sequence-specific DNA binding
FY149_RS00395	COG0628	permease
FY149_RS00405	COG2235	arginine
FY149_RS00440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY149_RS00450	COG0702	epimerase
FY149_RS00455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY149_RS00460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_RS00465	COG0745	RESPONSE REGULATOR receiver
FY149_RS00470	COG5002	protein histidine kinase activity
FY149_RS00485	COG2233	PERMEase
FY149_RS00545	COG0395	ABC-type sugar transport system, permease component
FY149_RS00550	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_RS00560	COG3842	ATPase activity
FY149_RS00595	COG1653	transport
FY149_RS00605	COG0395	ABC-type sugar transport system, permease component
FY149_RS00610	COG3842	ATPase activity
FY149_RS00625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY149_RS00630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_RS00635	COG1116	anion transmembrane transporter activity
FY149_RS00640	COG0395	ABC-type sugar transport system, permease component
FY149_RS00645	COG1175	transmembrane transport
FY149_RS00675	COG1609	Transcriptional regulator
FY149_RS00690	COG1082	Xylose isomerase domain protein TIM barrel
FY149_RS00695	COG3842	ATPase activity
FY149_RS00700	COG0395	ABC-type sugar transport system, permease component
FY149_RS00705	COG1175	transmembrane transport
FY149_RS00710	COG1653	transport
FY149_RS00715	COG1309	transcriptional regulator
FY149_RS00720	COG0673	inositol 2-dehydrogenase activity
FY149_RS00735	COG0673	inositol 2-dehydrogenase activity
FY149_RS00745	COG1278	Cold shock
FY149_RS00755	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY149_RS00780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY149_RS00785	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY149_RS00800	COG3842	ATPase activity
FY149_RS00805	COG0395	ABC-type sugar transport system, permease component
FY149_RS00810	COG1175	transmembrane transport
FY149_RS00820	COG3618	amidohydrolase
FY149_RS00825	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_RS00830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_RS00835	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS00840	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY149_RS00845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_RS00850	COG2186	Transcriptional regulator
FY149_RS00865	COG0667	Aldo Keto reductase
FY149_RS00895	COG4977	sequence-specific DNA binding
FY149_RS00900	COG2223	nitrite transmembrane transporter activity
FY149_RS00905	COG1609	Transcriptional regulator
FY149_RS00910	COG1063	alcohol dehydrogenase
FY149_RS00915	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS00925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_RS00930	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY149_RS00935	COG1175	transmembrane transport
FY149_RS00940	COG0395	ABC-type sugar transport system, permease component
FY149_RS00955	COG0395	ABC-type sugar transport system, permease component
FY149_RS00965	COG2182	Extracellular solute-binding protein
FY149_RS00970	COG0626	cystathionine gamma-synthase activity
FY149_RS00985	COG0454	-acetyltransferase
FY149_RS00990	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY149_RS01000	COG1121	(ABC) transporter
FY149_RS01005	COG0523	cobalamin synthesis protein
FY149_RS01020	COG0523	cobalamin synthesis protein
FY149_RS01025	COG1653	transport
FY149_RS01030	COG1175	transmembrane transport
FY149_RS01035	COG0395	ABC-type sugar transport system, permease component
FY149_RS01040	COG3842	ATPase activity
FY149_RS01050	COG3047	cAMP biosynthetic process
FY149_RS01100	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY149_RS01110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS01115	COG0765	amino acid transport
FY149_RS01120	COG1126	abc transporter atp-binding protein
FY149_RS01140	COG0793	Belongs to the peptidase S41A family
FY149_RS01175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY149_RS01185	COG0406	alpha-ribazole phosphatase activity
FY149_RS01225	COG3422	double-strand break repair
FY149_RS01340	COG1280	lysine exporter protein (LysE YggA)
FY149_RS01440	COG0583	DNA-binding transcription factor activity
FY149_RS01445	COG1879	ABC-type sugar transport system periplasmic component
FY149_RS01450	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS01455	COG1129	ABC transporter
FY149_RS01465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY149_RS01470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_RS01480	COG3257	ureidoglycine aminohydrolase activity
FY149_RS01490	COG5001	Diguanylate cyclase
FY149_RS01495	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY149_RS01505	COG0747	negative chemotaxis
FY149_RS01510	COG0601	transmembrane transport
FY149_RS01515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS01525	COG4608	Belongs to the ABC transporter superfamily
FY149_RS01530	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY149_RS01545	COG0346	lactoylglutathione lyase activity
FY149_RS01555	COG0129	dihydroxy-acid dehydratase activity
FY149_RS01560	COG1879	ABC-type sugar transport system periplasmic component
FY149_RS01565	COG1129	ABC transporter
FY149_RS01570	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS01575	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS01580	COG2186	Transcriptional regulator
FY149_RS01595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY149_RS01600	COG0587	DNA-directed DNA polymerase activity
FY149_RS01630	COG0673	inositol 2-dehydrogenase activity
FY149_RS01640	COG3842	ATPase activity
FY149_RS01645	COG0395	ABC-type sugar transport system, permease component
FY149_RS01650	COG1175	transmembrane transport
FY149_RS01655	COG1653	transport
FY149_RS01665	COG0673	inositol 2-dehydrogenase activity
FY149_RS01680	COG5001	Diguanylate cyclase
FY149_RS01690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS01695	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY149_RS01700	COG2894	cell division
FY149_RS01705	COG0850	regulation of cytokinetic process
FY149_RS01710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY149_RS01715	COG2186	Transcriptional regulator
FY149_RS01720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY149_RS01730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY149_RS01735	COG1063	alcohol dehydrogenase
FY149_RS01740	COG1312	Catalyzes the dehydration of D-mannonate
FY149_RS01760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY149_RS01765	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY149_RS01765	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY149_RS01770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS01785	COG0625	glutathione transferase activity
FY149_RS01790	COG4172	Belongs to the ABC transporter superfamily
FY149_RS01795	COG1921	L-seryl-tRNASec selenium transferase activity
FY149_RS01810	COG3964	amidohydrolase
FY149_RS01820	COG0601	transmembrane transport
FY149_RS01825	COG0747	negative chemotaxis
FY149_RS01830	COG0438	transferase activity, transferring glycosyl groups
FY149_RS01865	COG4989	oxidoreductase activity
FY149_RS01875	COG2188	Transcriptional regulator
FY149_RS01880	COG3842	ATPase activity
FY149_RS01885	COG1653	transport
FY149_RS01890	COG1175	transmembrane transport
FY149_RS01895	COG0395	ABC-type sugar transport system, permease component
FY149_RS01900	COG1501	Belongs to the glycosyl hydrolase 31 family
FY149_RS01910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_RS01915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY149_RS01920	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY149_RS01925	COG0352	thiamine-phosphate diphosphorylase activity
FY149_RS01930	COG0351	phosphomethylpyrimidine kinase
FY149_RS01935	COG1522	sequence-specific DNA binding
FY149_RS01940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY149_RS01945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS01960	COG2204	response regulator
FY149_RS01965	COG4191	Histidine kinase
FY149_RS01970	COG1301	dicarboxylic acid transport
FY149_RS01975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY149_RS01980	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS01990	COG1473	amidohydrolase
FY149_RS02010	COG1215	transferase activity, transferring glycosyl groups
FY149_RS02020	COG2942	2-epimerase
FY149_RS02045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_RS02055	COG2197	response regulator
FY149_RS02085	COG3307	-O-antigen
FY149_RS02090	COG1596	polysaccharide export
FY149_RS02095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY149_RS02105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY149_RS02110	COG0840	transmembrane signaling receptor activity
FY149_RS02115	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_RS02125	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS02135	COG2094	Belongs to the DNA glycosylase MPG family
FY149_RS02150	COG1609	Transcriptional regulator
FY149_RS02155	COG1653	transport
FY149_RS02170	COG3842	ATPase activity
FY149_RS02180	COG0673	inositol 2-dehydrogenase activity
FY149_RS02185	COG0602	queuosine metabolic process
FY149_RS02190	COG0720	synthase
FY149_RS02195	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY149_RS02205	COG0673	inositol 2-dehydrogenase activity
FY149_RS02220	COG0395	ABC-type sugar transport system, permease component
FY149_RS02225	COG1175	transmembrane transport
FY149_RS02250	COG0583	DNA-binding transcription factor activity
FY149_RS02255	COG0280	phosphate acetyltransferase
FY149_RS02255	COG0281	malic enzyme
FY149_RS02270	COG0765	amino acid transport
FY149_RS02275	COG1126	abc transporter atp-binding protein
FY149_RS02280	COG2079	MmgE PrpD family protein
FY149_RS02285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS02295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS02310	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY149_RS02320	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY149_RS02325	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY149_RS02330	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS02335	COG1129	ABC transporter
FY149_RS02350	COG1473	amidohydrolase
FY149_RS02355	COG0747	negative chemotaxis
FY149_RS02370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS02375	COG0601	transmembrane transport
FY149_RS02380	COG0583	DNA-binding transcription factor activity
FY149_RS02385	COG1446	asparaginase
FY149_RS02400	COG0747	negative chemotaxis
FY149_RS02420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS02425	COG0601	transmembrane transport
FY149_RS02430	COG2197	response regulator
FY149_RS02435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY149_RS02440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_RS02450	COG3842	ATPase activity
FY149_RS02455	COG0395	ABC-type sugar transport system, permease component
FY149_RS02460	COG1175	transmembrane transport
FY149_RS02470	COG0673	inositol 2-dehydrogenase activity
FY149_RS02475	COG0673	inositol 2-dehydrogenase activity
FY149_RS02495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_RS02500	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY149_RS02520	COG1595	DNA-templated transcription, initiation
FY149_RS02525	COG1120	ATPase activity
FY149_RS02530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_RS02545	COG2226	methyltransferase
FY149_RS02555	COG1120	ATPase activity
FY149_RS02560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_RS02605	COG1012	belongs to the aldehyde dehydrogenase family
FY149_RS02610	COG0473	3-isopropylmalate dehydrogenase activity
FY149_RS02615	COG1012	belongs to the aldehyde dehydrogenase family
FY149_RS02620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS02655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS02660	COG4172	Belongs to the ABC transporter superfamily
FY149_RS02665	COG1522	sequence-specific DNA binding
FY149_RS02675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS02690	COG0583	DNA-binding transcription factor activity
FY149_RS02700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS02705	COG1126	abc transporter atp-binding protein
FY149_RS02720	COG1473	amidohydrolase
FY149_RS02725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS02730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS02735	COG1959	2 iron, 2 sulfur cluster binding
FY149_RS02745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY149_RS02750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS02780	COG1960	acyl-CoA dehydrogenase activity
FY149_RS02790	COG0747	negative chemotaxis
FY149_RS02805	COG0444	Belongs to the ABC transporter superfamily
FY149_RS02815	COG0667	Aldo Keto reductase
FY149_RS02825	COG0583	DNA-binding transcription factor activity
FY149_RS02830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS02835	COG4166	transmembrane transport
FY149_RS02850	COG0747	negative chemotaxis
FY149_RS02855	COG1473	amidohydrolase
FY149_RS02860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS02875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS02880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS02890	COG1733	regulation of RNA biosynthetic process
FY149_RS02895	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS03030	COG4373	Mu-like prophage FluMu protein gp28
FY149_RS03035	COG4383	Mu-like prophage protein gp29
FY149_RS03040	COG2369	cell adhesion
FY149_RS03175	COG4608	Belongs to the ABC transporter superfamily
FY149_RS03180	COG0444	Belongs to the ABC transporter superfamily
FY149_RS03190	COG0601	transmembrane transport
FY149_RS03200	COG2186	Transcriptional regulator
FY149_RS03215	COG0300	oxidoreductase activity
FY149_RS03225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY149_RS03225	COG3453	Protein conserved in bacteria
FY149_RS03230	COG0640	Transcriptional regulator
FY149_RS03240	COG2391	methyltransferase activity
FY149_RS03245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY149_RS03255	COG0022	dehydrogenase e1 component
FY149_RS03265	COG1960	acyl-CoA dehydrogenase activity
FY149_RS03270	COG0183	Belongs to the thiolase family
FY149_RS03280	COG1960	acyl-CoA dehydrogenase activity
FY149_RS03285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY149_RS03305	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY149_RS03310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY149_RS03315	COG4952	isomerase
FY149_RS03320	COG3347	Dehydrogenase
FY149_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS03325	COG1349	DNA-binding transcription factor activity
FY149_RS03335	COG1129	ABC transporter
FY149_RS03340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS03345	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS03350	COG3254	rhamnose metabolic process
FY149_RS03365	COG2264	protein methyltransferase activity
FY149_RS03370	COG5001	Diguanylate cyclase
FY149_RS03385	COG4335	DNA alkylation repair
FY149_RS03390	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY149_RS03395	COG4208	sulfate ABC transporter
FY149_RS03405	COG4150	thiosulfate binding
FY149_RS03410	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY149_RS03425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY149_RS03435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY149_RS03445	COG1040	competence protein
FY149_RS03450	COG2226	methyltransferase
FY149_RS03465	COG0494	nUDIX hydrolase
FY149_RS03475	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY149_RS03480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY149_RS03485	COG0653	protein targeting
FY149_RS03490	COG0697	spore germination
FY149_RS03555	COG2244	polysaccharide biosynthetic process
FY149_RS03570	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY149_RS03580	COG3206	protein involved in exopolysaccharide biosynthesis
FY149_RS03580	COG0489	protein tyrosine kinase activity
FY149_RS03600	COG0438	transferase activity, transferring glycosyl groups
FY149_RS03605	COG0438	transferase activity, transferring glycosyl groups
FY149_RS03620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY149_RS03625	COG2273	Hydrolase Family 16
FY149_RS03625	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY149_RS03640	COG3842	ATPase activity
FY149_RS03645	COG3833	ABC-type maltose transport systems, permease component
FY149_RS03700	COG1396	sequence-specific DNA binding
FY149_RS03710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY149_RS03715	COG1129	ABC transporter
FY149_RS03720	COG4214	carbohydrate transport
FY149_RS03725	COG4213	ABC transporter substrate-binding protein
FY149_RS03740	COG0346	lactoylglutathione lyase activity
FY149_RS03745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY149_RS03745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY149_RS03750	COG4770	biotin carboxylase activity
FY149_RS03765	COG0625	glutathione transferase activity
FY149_RS03770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY149_RS03775	COG3800	Transcriptional regulator
FY149_RS03775	COG1396	sequence-specific DNA binding
FY149_RS03785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY149_RS03795	COG0300	oxidoreductase activity
FY149_RS03805	COG2096	Adenosyltransferase
FY149_RS03815	COG2086	electron transfer activity
FY149_RS03825	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY149_RS03835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY149_RS03840	COG0165	Argininosuccinate lyase
FY149_RS03875	COG2884	Cell division ATP-binding protein ftsE
FY149_RS03895	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY149_RS03905	COG0287	Prephenate dehydrogenase
FY149_RS03910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY149_RS03915	COG2226	methyltransferase
FY149_RS03920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY149_RS03940	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY149_RS03945	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY149_RS03985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY149_RS03990	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY149_RS04000	COG4974	Belongs to the 'phage' integrase family
FY149_RS04005	COG0825	malonyl-CoA metabolic process
FY149_RS04010	COG3034	peptidoglycan biosynthetic process
FY149_RS04015	COG0425	Belongs to the sulfur carrier protein TusA family
FY149_RS04015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY149_RS04020	COG0523	cobalamin synthesis protein
FY149_RS04025	COG1686	Belongs to the peptidase S11 family
FY149_RS04030	COG1473	amidohydrolase
FY149_RS04040	COG4953	penicillin-binding protein 1C
FY149_RS04045	COG2373	Large extracellular alpha-helical protein
FY149_RS04050	COG2835	tetraacyldisaccharide 4'-kinase activity
FY149_RS04080	COG0482	sulfurtransferase activity
FY149_RS04095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY149_RS04110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY149_RS04115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY149_RS04120	COG0037	tRNA processing
FY149_RS04130	COG2885	chlorophyll binding
FY149_RS04135	COG0823	Involved in the tonB-independent uptake of proteins
FY149_RS04155	COG0824	Thioesterase
FY149_RS04165	COG0494	nUDIX hydrolase
FY149_RS04180	COG2255	four-way junction helicase activity
FY149_RS04185	COG0632	four-way junction helicase activity
FY149_RS04190	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY149_RS04195	COG0840	transmembrane signaling receptor activity
FY149_RS04200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS04205	COG0217	transcriptional regulatory protein
FY149_RS04220	COG1692	metallophosphoesterase
FY149_RS04230	COG1253	flavin adenine dinucleotide binding
FY149_RS04265	COG3263	regulation of cellular component size
FY149_RS04270	COG0126	phosphoglycerate kinase activity
FY149_RS04275	COG3588	fructose-bisphosphate aldolase
FY149_RS04300	COG0254	rRNA binding
FY149_RS04305	COG1132	(ABC) transporter
FY149_RS04325	COG0483	inositol monophosphate 1-phosphatase activity
FY149_RS04355	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY149_RS04360	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY149_RS04365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY149_RS04370	COG0457	Tetratricopeptide repeat
FY149_RS04375	COG3750	Belongs to the UPF0335 family
FY149_RS04395	COG0469	pyruvate kinase activity
FY149_RS04400	COG3108	Peptidase M15
FY149_RS04405	COG2204	response regulator
FY149_RS04410	COG1164	Oligoendopeptidase f
FY149_RS04415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY149_RS04425	COG5310	Homospermidine synthase
FY149_RS04435	COG0737	Belongs to the 5'-nucleotidase family
FY149_RS04440	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY149_RS04445	COG0330	HflC and HflK could
FY149_RS04470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY149_RS04475	COG2951	lytic endotransglycosylase activity
FY149_RS04490	COG2205	protein histidine kinase activity
FY149_RS04505	COG0069	glutamate synthase activity
FY149_RS04505	COG0070	glutamate synthase
FY149_RS04505	COG0067	glutamate synthase
FY149_RS04520	COG2205	protein histidine kinase activity
FY149_RS04525	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY149_RS04530	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY149_RS04540	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY149_RS04550	COG0252	asparaginase activity
FY149_RS04560	COG1027	Aspartate ammonia-lyase
FY149_RS04565	COG2186	Transcriptional regulator
FY149_RS04605	COG4176	ABC-type proline glycine betaine transport system permease component
FY149_RS04610	COG0517	IMP dehydrogenase activity
FY149_RS04610	COG4175	Glycine betaine
FY149_RS04615	COG2986	histidine ammonia-lyase
FY149_RS04620	COG1609	Transcriptional regulator
FY149_RS04640	COG1082	Xylose isomerase domain protein TIM barrel
FY149_RS04645	COG0673	inositol 2-dehydrogenase activity
FY149_RS04650	COG1082	Xylose isomerase domain protein TIM barrel
FY149_RS04675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY149_RS04720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_RS04730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS04735	COG0601	transmembrane transport
FY149_RS04740	COG0747	negative chemotaxis
FY149_RS04750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY149_RS04755	COG1454	alcohol dehydrogenase
FY149_RS04795	COG2307	Protein conserved in bacteria
FY149_RS04795	COG2308	Evidence 4 Homologs of previously reported genes of
FY149_RS04810	COG0488	(ABC) transporter
FY149_RS04815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY149_RS04820	COG2186	Transcriptional regulator
FY149_RS04835	COG1175	transmembrane transport
FY149_RS04840	COG0395	ABC-type sugar transport system, permease component
FY149_RS04850	COG3842	ATPase activity
FY149_RS04875	COG1304	FMN binding
FY149_RS04890	COG1063	alcohol dehydrogenase
FY149_RS04895	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY149_RS04900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS04910	COG0765	amino acid transport
FY149_RS04915	COG0765	amino acid transport
FY149_RS04920	COG4221	oxidoreductase activity
FY149_RS04925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY149_RS04930	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS04935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_RS04950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY149_RS04965	COG0697	spore germination
FY149_RS04970	COG0697	spore germination
FY149_RS04975	COG0511	ligase activity, forming carbon-carbon bonds
FY149_RS04980	COG0439	Biotin carboxylase
FY149_RS04990	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY149_RS04995	COG1984	allophanate hydrolase subunit 2
FY149_RS05000	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY149_RS05005	COG3842	ATPase activity
FY149_RS05015	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY149_RS05025	COG0436	Aminotransferase
FY149_RS05040	COG0840	transmembrane signaling receptor activity
FY149_RS05045	COG1070	Carbohydrate kinase
FY149_RS05050	COG1830	Aldolase
FY149_RS05055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY149_RS05060	COG0667	Aldo Keto reductase
FY149_RS05070	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS05075	COG1129	ABC transporter
FY149_RS05080	COG1879	ABC-type sugar transport system periplasmic component
FY149_RS05125	COG0071	Belongs to the small heat shock protein (HSP20) family
FY149_RS05140	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY149_RS05155	COG0395	ABC-type sugar transport system, permease component
FY149_RS05170	COG3842	ATPase activity
FY149_RS05185	COG1648	precorrin-2 dehydrogenase activity
FY149_RS05185	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY149_RS05190	COG0243	molybdopterin cofactor binding
FY149_RS05200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY149_RS05205	COG1116	anion transmembrane transporter activity
FY149_RS05210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_RS05215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY149_RS05225	COG3707	response regulator
FY149_RS05230	COG1802	Transcriptional regulator
FY149_RS05235	COG1914	H( )-stimulated, divalent metal cation uptake system
FY149_RS05240	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY149_RS05245	COG4336	lyase activity
FY149_RS05250	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY149_RS05255	COG4770	biotin carboxylase activity
FY149_RS05260	COG0366	Alpha amylase catalytic
FY149_RS05270	COG4771	TonB-dependent receptor
FY149_RS05275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY149_RS05295	COG1414	Transcriptional regulator
FY149_RS05300	COG1475	DNA binding
FY149_RS05305	COG1192	Involved in chromosome partitioning
FY149_RS05335	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY149_RS05345	COG2986	histidine ammonia-lyase
FY149_RS05350	COG1228	amidohydrolase
FY149_RS05355	COG0402	S-adenosylhomocysteine deaminase activity
FY149_RS05395	COG4172	Belongs to the ABC transporter superfamily
FY149_RS05400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS05405	COG0601	transmembrane transport
FY149_RS05410	COG4166	transmembrane transport
FY149_RS05415	COG0395	ABC-type sugar transport system, permease component
FY149_RS05435	COG1566	PFAM secretion protein HlyD family protein
FY149_RS05450	COG2207	Transcriptional regulator
FY149_RS05455	COG1309	transcriptional regulator
FY149_RS05460	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS05485	COG1846	Transcriptional regulator
FY149_RS05490	COG0583	DNA-binding transcription factor activity
FY149_RS05495	COG2828	Protein conserved in bacteria
FY149_RS05510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_RS05525	COG0840	transmembrane signaling receptor activity
FY149_RS05545	COG1215	transferase activity, transferring glycosyl groups
FY149_RS05575	COG0583	DNA-binding transcription factor activity
FY149_RS05580	COG0346	lactoylglutathione lyase activity
FY149_RS05595	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY149_RS05615	COG0583	DNA-binding transcription factor activity
FY149_RS05620	COG0477	Major facilitator Superfamily
FY149_RS05630	COG2205	protein histidine kinase activity
FY149_RS05635	COG0745	RESPONSE REGULATOR receiver
FY149_RS05640	COG0671	phosphoesterase, PA-phosphatase related
FY149_RS05690	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY149_RS05695	COG0156	8-amino-7-oxononanoate synthase activity
FY149_RS05700	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY149_RS05705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY149_RS05710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY149_RS05725	COG0010	Belongs to the arginase family
FY149_RS05735	COG0697	spore germination
FY149_RS05740	COG0673	inositol 2-dehydrogenase activity
FY149_RS05760	COG0477	Major facilitator Superfamily
FY149_RS05775	COG2194	sulfuric ester hydrolase activity
FY149_RS05785	COG0583	DNA-binding transcription factor activity
FY149_RS05790	COG4774	siderophore transport
FY149_RS05805	COG1120	ATPase activity
FY149_RS05815	COG3474	cytochrome
FY149_RS05820	COG2137	regulation of response to DNA damage stimulus
FY149_RS05825	COG3386	PFAM SMP-30 Gluconolaconase
FY149_RS05835	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS05840	COG1129	ABC transporter
FY149_RS05845	COG1879	ABC-type sugar transport system periplasmic component
FY149_RS05850	COG4585	Histidine kinase
FY149_RS05855	COG2197	response regulator
FY149_RS05865	COG2133	pyrroloquinoline quinone binding
FY149_RS05875	COG0500	methyltransferase
FY149_RS05880	COG0564	pseudouridine synthase activity
FY149_RS05895	COG3448	diguanylate cyclase activity
FY149_RS05895	COG4175	Glycine betaine
FY149_RS05900	COG4176	ABC-type proline glycine betaine transport system permease component
FY149_RS05915	COG0784	Response regulator, receiver
FY149_RS05915	COG4191	Histidine kinase
FY149_RS05920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY149_RS05925	COG0489	protein tyrosine kinase activity
FY149_RS05925	COG3206	protein involved in exopolysaccharide biosynthesis
FY149_RS05930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY149_RS05935	COG1215	transferase activity, transferring glycosyl groups
FY149_RS05940	COG1215	transferase activity, transferring glycosyl groups
FY149_RS05945	COG1215	transferase activity, transferring glycosyl groups
FY149_RS05950	COG0438	transferase activity, transferring glycosyl groups
FY149_RS05955	COG2273	Hydrolase Family 16
FY149_RS05960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY149_RS05965	COG2244	polysaccharide biosynthetic process
FY149_RS05970	COG0463	Glycosyl transferase, family 2
FY149_RS05975	COG2327	Polysaccharide pyruvyl transferase
FY149_RS05980	COG1215	transferase activity, transferring glycosyl groups
FY149_RS06000	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY149_RS06005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS06020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY149_RS06020	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY149_RS06050	COG1523	belongs to the glycosyl hydrolase 13 family
FY149_RS06055	COG0033	Phosphoglucomutase
FY149_RS06060	COG0297	glycogen (starch) synthase activity
FY149_RS06065	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY149_RS06070	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY149_RS06075	COG0058	SHG alpha-glucan phosphorylase activity
FY149_RS06090	COG1794	racemase activity, acting on amino acids and derivatives
FY149_RS06095	COG1522	sequence-specific DNA binding
FY149_RS06105	COG2084	Dehydrogenase
FY149_RS06110	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS06115	COG1063	alcohol dehydrogenase
FY149_RS06125	COG4988	ABC transporter
FY149_RS06130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY149_RS06140	COG1294	oxidase, subunit
FY149_RS06170	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY149_RS06175	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY149_RS06205	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY149_RS06210	COG0539	negative regulation of cytoplasmic translation
FY149_RS06240	COG4221	oxidoreductase activity
FY149_RS06250	COG0747	negative chemotaxis
FY149_RS06255	COG0601	transmembrane transport
FY149_RS06260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS06265	COG0444	Belongs to the ABC transporter superfamily
FY149_RS06270	COG4608	Belongs to the ABC transporter superfamily
FY149_RS06275	COG0246	Mannitol dehydrogenase
FY149_RS06290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS06335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY149_RS06340	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS06355	COG4993	Dehydrogenase
FY149_RS06360	COG3685	Protein conserved in bacteria
FY149_RS06390	COG0693	protein deglycase activity
FY149_RS06410	COG0189	ligase activity
FY149_RS06415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_RS06420	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY149_RS06435	COG0435	Glutathione S-transferase
FY149_RS06440	COG0583	DNA-binding transcription factor activity
FY149_RS06445	COG1012	belongs to the aldehyde dehydrogenase family
FY149_RS06450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY149_RS06455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_RS06460	COG1116	anion transmembrane transporter activity
FY149_RS06470	COG1522	sequence-specific DNA binding
FY149_RS06485	COG0784	Response regulator, receiver
FY149_RS06505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY149_RS06520	COG0019	diaminopimelate decarboxylase activity
FY149_RS06535	COG0527	aspartate kinase activity
FY149_RS06545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY149_RS06550	COG2890	protein-(glutamine-N5) methyltransferase activity
FY149_RS06560	COG0542	response to heat
FY149_RS06565	COG0739	heme binding
FY149_RS06565	COG1196	nuclear chromosome segregation
FY149_RS06565	COG0741	lytic transglycosylase activity
FY149_RS06605	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY149_RS06615	COG1280	lysine exporter protein (LysE YggA)
FY149_RS06630	COG1309	transcriptional regulator
FY149_RS06635	COG4221	oxidoreductase activity
FY149_RS06640	COG1902	pentaerythritol trinitrate reductase activity
FY149_RS06645	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS06685	COG1278	Cold shock
FY149_RS06705	COG0753	catalase activity
FY149_RS06730	COG3920	Histidine kinase
FY149_RS06735	COG1280	lysine exporter protein (LysE YggA)
FY149_RS06755	COG0583	DNA-binding transcription factor activity
FY149_RS06790	COG0583	DNA-binding transcription factor activity
FY149_RS06800	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS06805	COG1846	Transcriptional regulator
FY149_RS06825	COG2186	Transcriptional regulator
FY149_RS06835	COG1126	abc transporter atp-binding protein
FY149_RS06845	COG0765	amino acid transport
FY149_RS06850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS06865	COG0436	Aminotransferase
FY149_RS06870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_RS06900	COG0405	Gamma-glutamyltransferase
FY149_RS06910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY149_RS06915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS06920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS06930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS06935	COG0747	negative chemotaxis
FY149_RS06940	COG0747	negative chemotaxis
FY149_RS06950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS06960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS06970	COG1129	ABC transporter
FY149_RS06975	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS06980	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS07005	COG0667	Aldo Keto reductase
FY149_RS07020	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS07025	COG1129	ABC transporter
FY149_RS07030	COG4213	ABC transporter substrate-binding protein
FY149_RS07050	COG4608	Belongs to the ABC transporter superfamily
FY149_RS07055	COG0444	Belongs to the ABC transporter superfamily
FY149_RS07060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS07065	COG0601	transmembrane transport
FY149_RS07070	COG0747	negative chemotaxis
FY149_RS07095	COG0765	amino acid transport
FY149_RS07100	COG4597	amino acid ABC transporter
FY149_RS07105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS07120	COG3177	Filamentation induced by cAMP protein fic
FY149_RS07145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS07175	COG3209	COG3209 Rhs family protein
FY149_RS07195	COG0745	RESPONSE REGULATOR receiver
FY149_RS07205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_RS07210	COG0577	efflux transmembrane transporter activity
FY149_RS07210	COG1136	(ABC) transporter
FY149_RS07220	COG1733	regulation of RNA biosynthetic process
FY149_RS07255	COG0534	Mate efflux family protein
FY149_RS07270	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY149_RS07275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY149_RS07285	COG1566	PFAM secretion protein HlyD family protein
FY149_RS07295	COG0625	glutathione transferase activity
FY149_RS07300	COG4221	oxidoreductase activity
FY149_RS07310	COG2376	Dihydroxyacetone kinase
FY149_RS07315	COG1522	sequence-specific DNA binding
FY149_RS07335	COG0431	NADPH-dependent FMN reductase
FY149_RS07345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS07355	COG4172	Belongs to the ABC transporter superfamily
FY149_RS07360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS07380	COG0277	FAD linked oxidase domain protein
FY149_RS07400	COG0778	Nitroreductase
FY149_RS07430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY149_RS07455	COG2318	DinB family
FY149_RS07460	COG0583	DNA-binding transcription factor activity
FY149_RS07475	COG1335	isochorismatase
FY149_RS07500	COG3842	ATPase activity
FY149_RS07505	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_RS07510	COG1177	transmembrane transport
FY149_RS07515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY149_RS07525	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY149_RS07540	COG1120	ATPase activity
FY149_RS07545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_RS07550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_RS07555	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY149_RS07560	COG1629	transport
FY149_RS07560	COG4774	siderophore transport
FY149_RS07565	COG4702	Belongs to the UPF0303 family
FY149_RS07585	COG1024	Enoyl-CoA hydratase
FY149_RS07590	COG1012	belongs to the aldehyde dehydrogenase family
FY149_RS07595	COG1653	transport
FY149_RS07600	COG1175	transmembrane transport
FY149_RS07605	COG0395	ABC-type sugar transport system, permease component
FY149_RS07610	COG3842	ATPase activity
FY149_RS07640	COG3474	cytochrome
FY149_RS07645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY149_RS07650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY149_RS07655	COG1845	cytochrome c oxidase, subunit III
FY149_RS07680	COG0577	efflux transmembrane transporter activity
FY149_RS07680	COG1136	(ABC) transporter
FY149_RS07745	COG3842	ATPase activity
FY149_RS07755	COG1177	transmembrane transport
FY149_RS07760	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_RS07775	COG1940	carbohydrate kinase activity
FY149_RS07795	COG1069	ribulokinase activity
FY149_RS07800	COG1349	DNA-binding transcription factor activity
FY149_RS07805	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS07830	COG0395	ABC-type sugar transport system, permease component
FY149_RS07840	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS07855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY149_RS07865	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY149_RS07875	COG0477	Major facilitator Superfamily
FY149_RS07925	COG1733	regulation of RNA biosynthetic process
FY149_RS07960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY149_RS07965	COG3938	Belongs to the proline racemase family
FY149_RS07970	COG4176	ABC-type proline glycine betaine transport system permease component
FY149_RS07980	COG3448	diguanylate cyclase activity
FY149_RS07980	COG4175	Glycine betaine
FY149_RS07990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS07995	COG1012	belongs to the aldehyde dehydrogenase family
FY149_RS08000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_RS08010	COG0047	phosphoribosylformylglycinamidine synthase activity
FY149_RS08015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS08025	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY149_RS08025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY149_RS08035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY149_RS08060	COG1309	transcriptional regulator
FY149_RS08075	COG1136	(ABC) transporter
FY149_RS08090	COG1063	alcohol dehydrogenase
FY149_RS08100	COG1879	ABC-type sugar transport system periplasmic component
FY149_RS08110	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS08130	COG0477	Major facilitator Superfamily
FY149_RS08260	COG5001	Diguanylate cyclase
FY149_RS08260	COG3300	MHYT domain
FY149_RS08285	COG1253	flavin adenine dinucleotide binding
FY149_RS08300	COG3842	ATPase activity
FY149_RS08305	COG0395	ABC-type sugar transport system, permease component
FY149_RS08310	COG1175	transmembrane transport
FY149_RS08315	COG1653	transport
FY149_RS08325	COG0673	inositol 2-dehydrogenase activity
FY149_RS08330	COG1609	Transcriptional regulator
FY149_RS08345	COG0583	DNA-binding transcription factor activity
FY149_RS08355	COG1879	ABC-type sugar transport system periplasmic component
FY149_RS08360	COG1129	ABC transporter
FY149_RS08365	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS08370	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS08375	COG1609	Transcriptional regulator
FY149_RS08385	COG0673	inositol 2-dehydrogenase activity
FY149_RS08445	COG0714	Associated with various cellular activities
FY149_RS08450	COG3256	nitric oxide reductase
FY149_RS08485	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY149_RS08490	COG3189	MarR family transcriptional regulator
FY149_RS08500	COG0826	peptidase U32
FY149_RS08535	COG4459	periplasmic nitrate reductase
FY149_RS08550	COG0243	molybdopterin cofactor binding
FY149_RS08560	COG3005	denitrification pathway
FY149_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS08580	COG1535	isochorismatase
FY149_RS08580	COG3433	isochorismatase activity
FY149_RS08585	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY149_RS08590	COG1169	isochorismate synthase
FY149_RS08600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY149_RS08600	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY149_RS08605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY149_RS08615	COG2375	cellular response to nickel ion
FY149_RS08625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_RS08630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_RS08640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS08650	COG4774	siderophore transport
FY149_RS08650	COG1629	transport
FY149_RS08655	COG1960	acyl-CoA dehydrogenase activity
FY149_RS08660	COG0583	DNA-binding transcription factor activity
FY149_RS08665	COG1609	Transcriptional regulator
FY149_RS08675	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_RS08685	COG3842	ATPase activity
FY149_RS08695	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY149_RS08700	COG0583	DNA-binding transcription factor activity
FY149_RS08705	COG2814	Major facilitator Superfamily
FY149_RS08710	COG1473	amidohydrolase
FY149_RS08725	COG0747	negative chemotaxis
FY149_RS08730	COG0601	transmembrane transport
FY149_RS08735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS08740	COG0444	Belongs to the ABC transporter superfamily
FY149_RS08745	COG4608	Belongs to the ABC transporter superfamily
FY149_RS08750	COG0583	DNA-binding transcription factor activity
FY149_RS08755	COG0747	negative chemotaxis
FY149_RS08765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS08770	COG0154	amidase activity
FY149_RS08775	COG0693	protein deglycase activity
FY149_RS08785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS08790	COG0601	transmembrane transport
FY149_RS08800	COG1473	amidohydrolase
FY149_RS08805	COG4172	Belongs to the ABC transporter superfamily
FY149_RS08810	COG2390	Transcriptional regulator
FY149_RS08820	COG1175	transmembrane transport
FY149_RS08825	COG0395	ABC-type sugar transport system, permease component
FY149_RS08875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY149_RS08895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY149_RS08900	COG1414	Transcriptional regulator
FY149_RS08905	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS08915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY149_RS08920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY149_RS08925	COG1121	(ABC) transporter
FY149_RS08930	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY149_RS08940	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY149_RS08945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY149_RS08950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY149_RS08955	COG0471	metal ion transport
FY149_RS08955	COG3273	potassium ion transport
FY149_RS08960	COG1253	flavin adenine dinucleotide binding
FY149_RS08965	COG1309	transcriptional regulator
FY149_RS08985	COG1609	Transcriptional regulator
FY149_RS08990	COG1070	Carbohydrate kinase
FY149_RS08995	COG2115	Belongs to the xylose isomerase family
FY149_RS09005	COG0778	Nitroreductase
FY149_RS09010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY149_RS09015	COG2011	ABC-type metal ion transport system permease component
FY149_RS09025	COG5001	Diguanylate cyclase
FY149_RS09025	COG3300	MHYT domain
FY149_RS09030	COG1054	Belongs to the UPF0176 family
FY149_RS09040	COG2954	triphosphatase activity
FY149_RS09045	COG0800	Aldolase
FY149_RS09065	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY149_RS09105	COG0523	cobalamin synthesis protein
FY149_RS09115	COG1846	Transcriptional regulator
FY149_RS09120	COG1609	Transcriptional regulator
FY149_RS09125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY149_RS09135	COG3718	enzyme involved in inositol metabolism
FY149_RS09145	COG3962	Belongs to the TPP enzyme family
FY149_RS09150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_RS09165	COG0411	ABC transporter
FY149_RS09180	COG0683	leucine binding
FY149_RS09195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS09205	COG0747	negative chemotaxis
FY149_RS09210	COG4172	Belongs to the ABC transporter superfamily
FY149_RS09235	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY149_RS09240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY149_RS09245	COG1126	abc transporter atp-binding protein
FY149_RS09250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS09255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS09260	COG0765	amino acid transport
FY149_RS09265	COG0765	amino acid transport
FY149_RS09270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY149_RS09275	COG3485	protocatechuate 3,4-dioxygenase
FY149_RS09280	COG3485	protocatechuate 3,4-dioxygenase
FY149_RS09285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY149_RS09295	COG0583	DNA-binding transcription factor activity
FY149_RS09310	COG1414	Transcriptional regulator
FY149_RS09320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY149_RS09325	COG0183	Belongs to the thiolase family
FY149_RS09330	COG1609	Transcriptional regulator
FY149_RS09345	COG1082	Xylose isomerase domain protein TIM barrel
FY149_RS09350	COG0673	inositol 2-dehydrogenase activity
FY149_RS09360	COG1609	Transcriptional regulator
FY149_RS09365	COG0395	ABC-type sugar transport system, permease component
FY149_RS09370	COG1175	transmembrane transport
FY149_RS09375	COG3842	ATPase activity
FY149_RS09385	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY149_RS09405	COG2814	Major facilitator Superfamily
FY149_RS09410	COG4774	siderophore transport
FY149_RS09415	COG3712	iron ion homeostasis
FY149_RS09425	COG1940	carbohydrate kinase activity
FY149_RS09430	COG0584	glycerophosphoryl diester phosphodiesterase
FY149_RS09435	COG0300	oxidoreductase activity
FY149_RS09450	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY149_RS09470	COG0667	Aldo Keto reductase
FY149_RS09475	COG0583	DNA-binding transcription factor activity
FY149_RS09485	COG1132	(ABC) transporter
FY149_RS09500	COG1216	Glycosyl transferase, family 2
FY149_RS09500	COG1442	glycosyl transferase family 8
FY149_RS09505	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY149_RS09515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY149_RS09535	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY149_RS09540	COG3754	Rhamnan synthesis protein F
FY149_RS09555	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY149_RS09560	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY149_RS09565	COG1088	dTDP-glucose 4,6-dehydratase activity
FY149_RS09570	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY149_RS09575	COG0210	DNA helicase
FY149_RS09585	COG1609	Transcriptional regulator
FY149_RS09590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY149_RS09590	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY149_RS09605	COG0395	ABC-type sugar transport system, permease component
FY149_RS09610	COG3842	ATPase activity
FY149_RS09620	COG0444	Belongs to the ABC transporter superfamily
FY149_RS09625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS09630	COG0601	transmembrane transport
FY149_RS09635	COG2186	Transcriptional regulator
FY149_RS09655	COG5001	Diguanylate cyclase
FY149_RS09655	COG3300	MHYT domain
FY149_RS09660	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS09670	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY149_RS09680	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY149_RS09685	COG0306	phosphate transporter
FY149_RS09690	COG1392	Phosphate transport regulator
FY149_RS09705	COG1566	PFAM secretion protein HlyD family protein
FY149_RS09710	COG0745	RESPONSE REGULATOR receiver
FY149_RS09715	COG2205	protein histidine kinase activity
FY149_RS09730	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY149_RS09745	COG4774	siderophore transport
FY149_RS09755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_RS09760	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_RS09765	COG1120	ATPase activity
FY149_RS09770	COG0583	DNA-binding transcription factor activity
FY149_RS09780	COG3119	arylsulfatase activity
FY149_RS09785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_RS09790	COG3842	ATPase activity
FY149_RS09795	COG0165	Argininosuccinate lyase
FY149_RS09800	COG0395	ABC-type sugar transport system, permease component
FY149_RS09805	COG1175	transmembrane transport
FY149_RS09810	COG2182	Extracellular solute-binding protein
FY149_RS09815	COG1940	carbohydrate kinase activity
FY149_RS09840	COG1486	melibiose metabolic process
FY149_RS09845	COG0747	negative chemotaxis
FY149_RS09850	COG0601	transmembrane transport
FY149_RS09855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS09860	COG4172	Belongs to the ABC transporter superfamily
FY149_RS09865	COG1486	melibiose metabolic process
FY149_RS09870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_RS09875	COG1129	ABC transporter
FY149_RS09875	COG0842	Transport permease protein
FY149_RS09880	COG0842	Transport permease protein
FY149_RS09895	COG0784	Response regulator, receiver
FY149_RS09900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY149_RS09910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_RS09915	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY149_RS09930	COG0765	amino acid transport
FY149_RS09940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS09950	COG3938	Belongs to the proline racemase family
FY149_RS09965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS09970	COG0765	amino acid transport
FY149_RS09975	COG0765	amino acid transport
FY149_RS09985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY149_RS10000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY149_RS10020	COG3383	formate dehydrogenase (NAD+) activity
FY149_RS10030	COG2223	nitrite transmembrane transporter activity
FY149_RS10035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_RS10045	COG2186	Transcriptional regulator
FY149_RS10050	COG0747	negative chemotaxis
FY149_RS10055	COG0601	transmembrane transport
FY149_RS10060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS10065	COG4172	Belongs to the ABC transporter superfamily
FY149_RS10070	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_RS10080	COG2186	Transcriptional regulator
FY149_RS10085	COG0747	negative chemotaxis
FY149_RS10090	COG0601	transmembrane transport
FY149_RS10095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS10100	COG0405	Gamma-glutamyltransferase
FY149_RS10110	COG0483	inositol monophosphate 1-phosphatase activity
FY149_RS10120	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY149_RS10125	COG0395	ABC-type sugar transport system, permease component
FY149_RS10145	COG3237	CsbD-like
FY149_RS10155	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY149_RS10160	COG3181	Tripartite tricarboxylate transporter family receptor
FY149_RS10165	COG5265	(ABC) transporter
FY149_RS10170	COG0488	(ABC) transporter
FY149_RS10195	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY149_RS10200	COG0110	maltose O-acetyltransferase activity
FY149_RS10210	COG1063	alcohol dehydrogenase
FY149_RS10215	COG3284	Transcriptional regulator
FY149_RS10235	COG1129	ABC transporter
FY149_RS10240	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS10245	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS10255	COG0572	uridine kinase
FY149_RS10260	COG1082	Xylose isomerase domain protein TIM barrel
FY149_RS10285	COG4178	(ABC) transporter
FY149_RS10320	COG0640	Transcriptional regulator
FY149_RS10335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY149_RS10340	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY149_RS10345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY149_RS10350	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY149_RS10355	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY149_RS10360	COG1420	regulation of RNA biosynthetic process
FY149_RS10365	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY149_RS10370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY149_RS10375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY149_RS10385	COG1137	ATPase activity
FY149_RS10390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY149_RS10400	COG0616	signal peptide processing
FY149_RS10405	COG0776	regulation of translation
FY149_RS10415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY149_RS10420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY149_RS10425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY149_RS10440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY149_RS10445	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY149_RS10450	COG0728	peptidoglycan biosynthetic process
FY149_RS10460	COG0180	Tryptophanyl-tRNA synthetase
FY149_RS10470	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY149_RS10475	COG1214	PFAM Peptidase M22, glycoprotease
FY149_RS10495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY149_RS10500	COG1702	phosphate starvation-inducible protein PhoH
FY149_RS10505	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY149_RS10515	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY149_RS10520	COG1396	sequence-specific DNA binding
FY149_RS10525	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY149_RS10530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY149_RS10535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_RS10545	COG0242	peptide deformylase activity
FY149_RS10550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY149_RS10555	COG0101	tRNA pseudouridine synthase activity
FY149_RS10565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY149_RS10570	COG2171	N-acyltransferase activity
FY149_RS10580	COG0840	transmembrane signaling receptor activity
FY149_RS10585	COG1957	nucleoside hydrolase
FY149_RS10590	COG0071	Belongs to the small heat shock protein (HSP20) family
FY149_RS10615	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY149_RS10625	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY149_RS10630	COG0706	membrane insertase activity
FY149_RS10635	COG0594	ribonuclease P activity
FY149_RS10640	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY149_RS10645	COG0840	transmembrane signaling receptor activity
FY149_RS10660	COG2226	methyltransferase
FY149_RS10665	COG3842	ATPase activity
FY149_RS10670	COG1175	transmembrane transport
FY149_RS10675	COG0395	ABC-type sugar transport system, permease component
FY149_RS10690	COG0427	acetyl-CoA hydrolase
FY149_RS10700	COG3938	Belongs to the proline racemase family
FY149_RS10705	COG0418	dihydroorotase activity
FY149_RS10710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY149_RS10730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY149_RS10735	COG0166	Belongs to the GPI family
FY149_RS10740	COG0318	PFAM AMP-dependent synthetase and ligase
FY149_RS10745	COG3842	ATPase activity
FY149_RS10750	COG1840	ABC-type Fe3 transport system, periplasmic component
FY149_RS10755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY149_RS10760	COG4774	siderophore transport
FY149_RS10805	COG2326	polyphosphate kinase activity
FY149_RS10810	COG5002	protein histidine kinase activity
FY149_RS10815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY149_RS10820	COG0573	inorganic phosphate transmembrane transporter activity
FY149_RS10830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY149_RS10835	COG0704	Plays a role in the regulation of phosphate uptake
FY149_RS10840	COG0745	RESPONSE REGULATOR receiver
FY149_RS10850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY149_RS10855	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY149_RS10865	COG2967	ApaG domain
FY149_RS10875	COG0717	Belongs to the dCTP deaminase family
FY149_RS10885	COG0582	viral genome integration into host DNA
FY149_RS10910	COG0419	ATPase involved in DNA repair
FY149_RS10930	COG1396	sequence-specific DNA binding
FY149_RS10970	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY149_RS10975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY149_RS11025	COG0167	dihydroorotate dehydrogenase activity
FY149_RS11060	COG1959	2 iron, 2 sulfur cluster binding
FY149_RS11065	COG1201	RNA secondary structure unwinding
FY149_RS11095	COG1960	acyl-CoA dehydrogenase activity
FY149_RS11100	COG0183	Belongs to the thiolase family
FY149_RS11105	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY149_RS11105	COG1024	Enoyl-CoA hydratase
FY149_RS11130	COG1320	monovalent cation:proton antiporter activity
FY149_RS11135	COG2212	antiporter activity
FY149_RS11140	COG1863	multisubunit Na H antiporter MnhE subunit
FY149_RS11145	COG0651	ATP synthesis coupled electron transport
FY149_RS11150	COG1006	Multisubunit Na H antiporter MnhC subunit
FY149_RS11155	COG2111	Na H antiporter
FY149_RS11155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY149_RS11165	COG0840	transmembrane signaling receptor activity
FY149_RS11175	COG0745	RESPONSE REGULATOR receiver
FY149_RS11180	COG2198	Histidine kinase
FY149_RS11180	COG0643	Histidine kinase
FY149_RS11185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY149_RS11190	COG2201	protein-glutamate methylesterase activity
FY149_RS11195	COG0745	RESPONSE REGULATOR receiver
FY149_RS11200	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY149_RS11210	COG1766	The M ring may be actively involved in energy transduction
FY149_RS11215	COG2771	luxR family
FY149_RS11225	COG0840	transmembrane signaling receptor activity
FY149_RS11225	COG2972	Histidine kinase
FY149_RS11230	COG2205	protein histidine kinase activity
FY149_RS11230	COG2198	Histidine kinase
FY149_RS11230	COG0784	Response regulator, receiver
FY149_RS11235	COG1970	mechanosensitive ion channel activity
FY149_RS11240	COG0436	Aminotransferase
FY149_RS11255	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY149_RS11260	COG0424	maF-like protein
FY149_RS11265	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY149_RS11275	COG5328	Belongs to the UPF0262 family
FY149_RS11280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY149_RS11290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY149_RS11310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY149_RS11320	COG1338	Plays a role in the flagellum-specific transport system
FY149_RS11330	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY149_RS11340	COG1706	bacterial-type flagellum-dependent cell motility
FY149_RS11345	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY149_RS11350	COG4786	Flagellar basal body rod
FY149_RS11355	COG1677	Flagellar hook-basal body complex protein FliE
FY149_RS11360	COG1558	bacterial-type flagellum-dependent cell motility
FY149_RS11365	COG1815	bacterial-type flagellum-dependent cell motility
FY149_RS11375	COG1157	protein secretion by the type III secretion system
FY149_RS11380	COG4786	Flagellar basal body rod
FY149_RS11390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY149_RS11395	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY149_RS11400	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY149_RS11405	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY149_RS11410	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY149_RS11430	COG1360	Flagellar Motor Protein
FY149_RS11475	COG5443	negative regulation of bacterial-type flagellum assembly
FY149_RS11480	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY149_RS11490	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY149_RS11530	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY149_RS11535	COG1609	Transcriptional regulator
FY149_RS11540	COG1653	transport
FY149_RS11545	COG1175	transmembrane transport
FY149_RS11550	COG0395	ABC-type sugar transport system, permease component
FY149_RS11555	COG0366	Alpha amylase catalytic
FY149_RS11560	COG3842	ATPase activity
FY149_RS11575	COG0129	dihydroxy-acid dehydratase activity
FY149_RS11580	COG0363	glucosamine-6-phosphate deaminase activity
FY149_RS11585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY149_RS11590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS11600	COG2081	HI0933 family
FY149_RS11620	COG2224	Isocitrate lyase
FY149_RS11635	COG3842	ATPase activity
FY149_RS11640	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_RS11645	COG1177	transmembrane transport
FY149_RS11660	COG2205	protein histidine kinase activity
FY149_RS11670	COG0248	Ppx GppA phosphatase
FY149_RS11675	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY149_RS11680	COG0477	Major facilitator Superfamily
FY149_RS11710	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY149_RS11715	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY149_RS11725	COG0142	geranyltranstransferase activity
FY149_RS11750	COG0752	glycyl-tRNA synthetase alpha subunit
FY149_RS11760	COG1704	LemA family
FY149_RS11765	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY149_RS11775	COG0751	glycine-tRNA ligase activity
FY149_RS11780	COG1683	Conserved Protein
FY149_RS11785	COG0840	transmembrane signaling receptor activity
FY149_RS11795	COG0151	Belongs to the GarS family
FY149_RS11800	COG2183	response to ionizing radiation
FY149_RS11805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY149_RS11830	COG0583	DNA-binding transcription factor activity
FY149_RS11850	COG0306	phosphate transporter
FY149_RS11860	COG0561	phosphatase activity
FY149_RS11865	COG0438	transferase activity, transferring glycosyl groups
FY149_RS11870	COG2186	Transcriptional regulator
FY149_RS11885	COG0583	DNA-binding transcription factor activity
FY149_RS11890	COG0277	FAD linked oxidase domain protein
FY149_RS11895	COG0277	FAD linked oxidase domain protein
FY149_RS11900	COG0247	lactate metabolic process
FY149_RS11910	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_RS11915	COG2818	Glycosylase
FY149_RS11925	COG2855	membrane
FY149_RS11930	COG0583	DNA-binding transcription factor activity
FY149_RS11960	COG0124	histidyl-tRNA synthetase
FY149_RS11970	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY149_RS11975	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY149_RS11980	COG2259	Doxx family
FY149_RS11990	COG0459	protein refolding
FY149_RS11995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY149_RS12005	COG0196	riboflavin kinase activity
FY149_RS12010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY149_RS12020	COG0590	tRNA wobble adenosine to inosine editing
FY149_RS12025	COG1187	pseudouridine synthase activity
FY149_RS12030	COG0742	ribosomal rna small subunit methyltransferase
FY149_RS12035	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY149_RS12045	COG0312	modulator of DNA gyrase
FY149_RS12050	COG0483	inositol monophosphate 1-phosphatase activity
FY149_RS12060	COG1519	Transferase
FY149_RS12070	COG1663	tetraacyldisaccharide 4'-kinase activity
FY149_RS12080	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY149_RS12085	COG0745	RESPONSE REGULATOR receiver
FY149_RS12090	COG3300	MHYT domain
FY149_RS12090	COG5001	Diguanylate cyclase
FY149_RS12095	COG3386	PFAM SMP-30 Gluconolaconase
FY149_RS12100	COG0800	Aldolase
FY149_RS12105	COG3734	2-keto-3-deoxy-galactonokinase
FY149_RS12110	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS12115	COG1414	Transcriptional regulator
FY149_RS12120	COG2197	response regulator
FY149_RS12135	COG0598	Magnesium transport protein CorA
FY149_RS12140	COG3158	transport of potassium into the cell
FY149_RS12155	COG0356	it plays a direct role in the translocation of protons across the membrane
FY149_RS12165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY149_RS12170	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY149_RS12185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY149_RS12205	COG0009	L-threonylcarbamoyladenylate synthase
FY149_RS12215	COG4638	Rieske (2fe-2S)
FY149_RS12240	COG1960	acyl-CoA dehydrogenase activity
FY149_RS12255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY149_RS12260	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY149_RS12265	COG0840	transmembrane signaling receptor activity
FY149_RS12275	COG1522	sequence-specific DNA binding
FY149_RS12300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY149_RS12305	COG1741	Belongs to the pirin family
FY149_RS12310	COG1722	exodeoxyribonuclease VII activity
FY149_RS12315	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY149_RS12320	COG1268	BioY protein
FY149_RS12325	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY149_RS12330	COG1122	ATPase activity
FY149_RS12335	COG3214	Protein conserved in bacteria
FY149_RS12340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY149_RS12340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY149_RS12345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY149_RS12365	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY149_RS12380	COG0259	pyridoxamine-phosphate oxidase activity
FY149_RS12410	COG0312	modulator of DNA gyrase
FY149_RS12425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY149_RS12430	COG0109	protoheme IX farnesyltransferase activity
FY149_RS12440	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY149_RS12455	COG3346	SURF1 family
FY149_RS12460	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY149_RS12465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY149_RS12470	COG0328	RNA-DNA hybrid ribonuclease activity
FY149_RS12480	COG0678	peroxiredoxin activity
FY149_RS12480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY149_RS12490	COG1678	Uncharacterized ACR, COG1678
FY149_RS12495	COG3237	CsbD-like
FY149_RS12505	COG5001	Diguanylate cyclase
FY149_RS12505	COG3300	MHYT domain
FY149_RS12510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY149_RS12515	COG0612	Peptidase, M16
FY149_RS12540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY149_RS12545	COG1802	Transcriptional regulator
FY149_RS12560	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY149_RS12565	COG3609	addiction module antidote protein, CC2985 family
FY149_RS12570	COG3668	Plasmid stabilization system
FY149_RS12580	COG1194	a g-specific adenine glycosylase
FY149_RS12595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY149_RS12600	COG1196	nuclear chromosome segregation
FY149_RS12605	COG2514	catechol 2,3-dioxygenase activity
FY149_RS12610	COG0574	Belongs to the PEP-utilizing enzyme family
FY149_RS12610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY149_RS12620	COG1823	symporter activity
FY149_RS12645	COG0579	oxidoreductase
FY149_RS12660	COG2895	sulfate adenylyltransferase (ATP) activity
FY149_RS12665	COG0175	sulfate reduction
FY149_RS12670	COG0175	sulfate reduction
FY149_RS12675	COG1959	2 iron, 2 sulfur cluster binding
FY149_RS12680	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY149_RS12685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY149_RS12690	COG4208	sulfate ABC transporter
FY149_RS12695	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY149_RS12705	COG2199	diguanylate cyclase activity
FY149_RS12705	COG2200	EAL domain
FY149_RS12705	COG2203	Gaf domain
FY149_RS12715	COG1309	transcriptional regulator
FY149_RS12720	COG1012	belongs to the aldehyde dehydrogenase family
FY149_RS12725	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY149_RS12755	COG0625	glutathione transferase activity
FY149_RS12765	COG0477	Major facilitator Superfamily
FY149_RS12775	COG3657	addiction module killer protein
FY149_RS12785	COG1793	dna ligase
FY149_RS12805	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_RS12810	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_RS12815	COG1846	Transcriptional regulator
FY149_RS12820	COG1764	response to oxidative stress
FY149_RS12835	COG0488	(ABC) transporter
FY149_RS12870	COG4221	oxidoreductase activity
FY149_RS12885	COG0433	COG0433 Predicted ATPase
FY149_RS12895	COG1733	regulation of RNA biosynthetic process
FY149_RS12900	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY149_RS12915	COG0656	L-ascorbic acid biosynthetic process
FY149_RS12920	COG3781	membrane
FY149_RS12925	COG2378	regulation of single-species biofilm formation
FY149_RS12935	COG4106	trans-aconitate 2-methyltransferase activity
FY149_RS12940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY149_RS12945	COG0840	transmembrane signaling receptor activity
FY149_RS12950	COG0583	DNA-binding transcription factor activity
FY149_RS12965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY149_RS12985	COG3909	cytochrome
FY149_RS12990	COG2010	Cytochrome c
FY149_RS13025	COG0789	Transcriptional regulator
FY149_RS13050	COG4175	Glycine betaine
FY149_RS13050	COG0517	IMP dehydrogenase activity
FY149_RS13055	COG4176	ABC-type proline glycine betaine transport system permease component
FY149_RS13080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_RS13090	COG2169	Transcriptional regulator
FY149_RS13090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY149_RS13100	COG2514	catechol 2,3-dioxygenase activity
FY149_RS13115	COG1272	protein, Hemolysin III
FY149_RS13125	COG1280	lysine exporter protein (LysE YggA)
FY149_RS13130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY149_RS13135	COG2111	Na H antiporter
FY149_RS13135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY149_RS13140	COG2111	Na H antiporter
FY149_RS13145	COG1006	Multisubunit Na H antiporter MnhC subunit
FY149_RS13150	COG0651	ATP synthesis coupled electron transport
FY149_RS13155	COG1863	multisubunit Na H antiporter MnhE subunit
FY149_RS13160	COG2212	antiporter activity
FY149_RS13165	COG1320	monovalent cation:proton antiporter activity
FY149_RS13170	COG4957	zinc ion binding
FY149_RS13185	COG2166	iron-sulfur cluster assembly
FY149_RS13195	COG2205	protein histidine kinase activity
FY149_RS13240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY149_RS13245	COG2983	Belongs to the UPF0260 family
FY149_RS13260	COG2217	Heavy metal translocating P-type atpase
FY149_RS13290	COG2814	Major facilitator Superfamily
FY149_RS13300	COG1621	beta-fructofuranosidase activity
FY149_RS13305	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY149_RS13355	COG4695	Portal protein
FY149_RS13470	COG3436	PFAM IS66 Orf2 family protein
FY149_RS13475	COG4372	Transposase
FY149_RS13480	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FY149_RS13560	COG4235	cytochrome complex assembly
FY149_RS13565	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY149_RS13570	COG1138	Cytochrome C-type biogenesis protein
FY149_RS13575	COG3088	subunit of a heme lyase
FY149_RS13580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY149_RS13585	COG0745	RESPONSE REGULATOR receiver
FY149_RS13590	COG2205	protein histidine kinase activity
FY149_RS13595	COG3011	Protein conserved in bacteria
FY149_RS13600	COG3713	MltA-interacting MipA family protein
FY149_RS13605	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY149_RS13610	COG2202	Pas domain
FY149_RS13610	COG2205	protein histidine kinase activity
FY149_RS13620	COG0308	aminopeptidase N
FY149_RS13625	COG0697	spore germination
FY149_RS13640	COG0443	Heat shock 70 kDa protein
FY149_RS13675	COG0604	alcohol dehydrogenase
FY149_RS13680	COG1733	regulation of RNA biosynthetic process
FY149_RS13685	COG1968	undecaprenyl-diphosphatase activity
FY149_RS13690	COG2239	Acts as a magnesium transporter
FY149_RS13695	COG2814	Major facilitator Superfamily
FY149_RS13720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY149_RS13750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY149_RS13795	COG0741	lytic transglycosylase activity
FY149_RS13800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_RS13805	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY149_RS13810	COG0840	transmembrane signaling receptor activity
FY149_RS13820	COG1758	RNA polymerase activity
FY149_RS13840	COG0736	holo-[acyl-carrier-protein] synthase activity
FY149_RS13845	COG0681	Belongs to the peptidase S26 family
FY149_RS13850	COG0571	ribonuclease III activity
FY149_RS13855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY149_RS13865	COG0784	Response regulator, receiver
FY149_RS13870	COG1381	Involved in DNA repair and RecF pathway recombination
FY149_RS13880	COG2226	methyltransferase
FY149_RS13890	COG1418	mRNA catabolic process
FY149_RS13900	COG0346	lactoylglutathione lyase activity
FY149_RS13915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_RS13920	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY149_RS13925	COG0668	transmembrane transport
FY149_RS13935	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY149_RS13965	COG1742	UPF0060 membrane protein
FY149_RS13985	COG1183	phosphatidylcholine synthase activity
FY149_RS13990	COG0688	phosphatidylethanolamine metabolic process
FY149_RS13995	COG5265	(ABC) transporter
FY149_RS14035	COG2852	Protein conserved in bacteria
FY149_RS14040	COG0215	cysteine-tRNA ligase activity
FY149_RS14045	COG4221	oxidoreductase activity
FY149_RS14050	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY149_RS14055	COG1286	toxin biosynthetic process
FY149_RS14070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY149_RS14080	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY149_RS14090	COG0305	Participates in initiation and elongation during chromosome replication
FY149_RS14110	COG0359	binds to the 23S rRNA
FY149_RS14120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY149_RS14125	COG0360	Binds together with S18 to 16S ribosomal RNA
FY149_RS14135	COG0667	Aldo Keto reductase
FY149_RS14140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY149_RS14150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY149_RS14155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY149_RS14165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY149_RS14170	COG1561	YicC-like family, N-terminal region
FY149_RS14175	COG0194	GDP metabolic process
FY149_RS14190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY149_RS14195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY149_RS14205	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY149_RS14220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY149_RS14240	COG2203	Gaf domain
FY149_RS14240	COG4251	negative regulation of phosphorylation
FY149_RS14240	COG5001	Diguanylate cyclase
FY149_RS14240	COG3706	GGDEF domain
FY149_RS14245	COG3300	MHYT domain
FY149_RS14245	COG5001	Diguanylate cyclase
FY149_RS14250	COG4191	Histidine kinase
FY149_RS14255	COG4566	intracellular signal transduction
FY149_RS14265	COG0488	(ABC) transporter
FY149_RS14270	COG3706	GGDEF domain
FY149_RS14280	COG0105	UTP biosynthetic process
FY149_RS14300	COG0314	molybdopterin synthase activity
FY149_RS14310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY149_RS14315	COG0322	excinuclease ABC activity
FY149_RS14320	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS14345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY149_RS14350	COG0243	molybdopterin cofactor binding
FY149_RS14365	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY149_RS14370	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY149_RS14375	COG2226	methyltransferase
FY149_RS14380	COG0628	permease
FY149_RS14390	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY149_RS14395	COG0248	Ppx GppA phosphatase
FY149_RS14420	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY149_RS14430	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY149_RS14435	COG0477	Major facilitator Superfamily
FY149_RS14440	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY149_RS14450	COG0840	transmembrane signaling receptor activity
FY149_RS14455	COG0659	secondary active sulfate transmembrane transporter activity
FY149_RS14465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY149_RS14470	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY149_RS14480	COG0113	porphobilinogen synthase activity
FY149_RS14500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY149_RS14505	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY149_RS14510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY149_RS14510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY149_RS14520	COG1280	lysine exporter protein (LysE YggA)
FY149_RS14525	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY149_RS14530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY149_RS14535	COG2814	Major facilitator Superfamily
FY149_RS14540	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY149_RS14560	COG0416	fatty acid biosynthetic process
FY149_RS14565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY149_RS14570	COG0776	regulation of translation
FY149_RS14605	COG0601	transmembrane transport
FY149_RS14610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS14615	COG0444	Belongs to the ABC transporter superfamily
FY149_RS14625	COG0747	negative chemotaxis
FY149_RS14635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY149_RS14640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY149_RS14655	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY149_RS14660	COG0583	DNA-binding transcription factor activity
FY149_RS14665	COG0737	Belongs to the 5'-nucleotidase family
FY149_RS14685	COG2897	thiosulfate sulfurtransferase activity
FY149_RS14700	COG0415	Belongs to the DNA photolyase family
FY149_RS14710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY149_RS14740	COG3932	Exopolysaccharide synthesis, ExoD
FY149_RS14745	COG1238	metal cluster binding
FY149_RS14820	COG1612	heme a metabolic process
FY149_RS14830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY149_RS14835	COG0010	Belongs to the arginase family
FY149_RS14840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY149_RS14845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY149_RS14855	COG1832	CoA-binding protein
FY149_RS14880	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS14885	COG2124	cytochrome p450
FY149_RS14890	COG2199	diguanylate cyclase activity
FY149_RS14895	COG0740	serine-type endopeptidase activity
FY149_RS14900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY149_RS14905	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY149_RS14915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY149_RS14945	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY149_RS14950	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY149_RS14955	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY149_RS14965	COG0649	NAD binding
FY149_RS14975	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY149_RS14980	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY149_RS14990	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY149_RS14995	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY149_RS15005	COG0713	ATP synthesis coupled electron transport
FY149_RS15020	COG1007	ATP synthesis coupled electron transport
FY149_RS15025	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY149_RS15025	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY149_RS15040	COG0442	prolyl-tRNA aminoacylation
FY149_RS15050	COG1136	(ABC) transporter
FY149_RS15065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY149_RS15085	COG0784	Response regulator, receiver
FY149_RS15095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY149_RS15100	COG0477	Major facilitator Superfamily
FY149_RS15115	COG0557	exoribonuclease II activity
FY149_RS15120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY149_RS15130	COG0758	DNA mediated transformation
FY149_RS15135	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY149_RS15145	COG0540	Belongs to the ATCase OTCase family
FY149_RS15160	COG1960	acyl-CoA dehydrogenase activity
FY149_RS15165	COG0456	acetyltransferase
FY149_RS15185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY149_RS15190	COG2824	Alkylphosphonate utilization operon protein PhnA
FY149_RS15195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY149_RS15200	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY149_RS15205	COG0154	amidase activity
FY149_RS15210	COG0456	acetyltransferase
FY149_RS15215	COG3811	Belongs to the UPF0386 family
FY149_RS15230	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY149_RS15260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY149_RS15265	COG0439	Biotin carboxylase
FY149_RS15270	COG0511	ligase activity, forming carbon-carbon bonds
FY149_RS15275	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY149_RS15285	COG0436	Aminotransferase
FY149_RS15305	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS15310	COG1530	ribonuclease E activity
FY149_RS15320	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY149_RS15340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY149_RS15345	COG0384	phenazine biosynthesis protein PhzF
FY149_RS15365	COG0633	Ferredoxin
FY149_RS15375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FY149_RS15380	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY149_RS15385	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY149_RS15395	COG3768	UPF0283 membrane protein
FY149_RS15400	COG3106	COG3106 Predicted ATPase
FY149_RS15430	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY149_RS15465	COG0537	adenosine 5'-monophosphoramidase activity
FY149_RS15495	COG0052	Belongs to the universal ribosomal protein uS2 family
FY149_RS15500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY149_RS15505	COG0528	UMP kinase activity
FY149_RS15510	COG0233	cytoplasmic translational termination
FY149_RS15515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY149_RS15525	COG0750	zinc metalloprotease
FY149_RS15530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY149_RS15535	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY149_RS15540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY149_RS15545	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY149_RS15550	COG3494	Protein of unknown function (DUF1009)
FY149_RS15555	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY149_RS15560	COG2186	Transcriptional regulator
FY149_RS15570	COG0765	amino acid transport
FY149_RS15575	COG0765	amino acid transport
FY149_RS15585	COG0372	Belongs to the citrate synthase family
FY149_RS15600	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY149_RS15625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY149_RS15630	COG1459	type II secretion system
FY149_RS15685	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY149_RS15690	COG0148	phosphopyruvate hydratase activity
FY149_RS15700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY149_RS15705	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY149_RS15705	COG0022	dehydrogenase e1 component
FY149_RS15710	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY149_RS15720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY149_RS15730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY149_RS15735	COG0697	spore germination
FY149_RS15755	COG2867	negative regulation of translational initiation
FY149_RS15760	COG1546	Belongs to the CinA family
FY149_RS15765	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY149_RS15765	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY149_RS15775	COG3852	Histidine kinase
FY149_RS15780	COG2204	response regulator
FY149_RS15785	COG5000	phosphorelay sensor kinase activity
FY149_RS15790	COG2204	response regulator
FY149_RS15795	COG0569	domain protein
FY149_RS15800	COG1923	regulation of RNA biosynthetic process
FY149_RS15805	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY149_RS15810	COG3956	TIGRFAM MazG family protein
FY149_RS15820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY149_RS15820	COG1648	precorrin-2 dehydrogenase activity
FY149_RS15860	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY149_RS15860	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY149_RS15865	COG0509	glycine decarboxylation via glycine cleavage system
FY149_RS15870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY149_RS15895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY149_RS15900	COG0564	pseudouridine synthase activity
FY149_RS15920	COG0251	oxidation-reduction process
FY149_RS15925	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY149_RS15935	COG1671	Belongs to the UPF0178 family
FY149_RS15950	COG0450	alkyl hydroperoxide reductase
FY149_RS15955	COG0625	glutathione transferase activity
FY149_RS15975	COG0431	NADPH-dependent FMN reductase
FY149_RS15985	COG0798	PFAM Bile acid sodium symporter
FY149_RS15990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY149_RS16005	COG0321	lipoyl(octanoyl) transferase activity
FY149_RS16005	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY149_RS16010	COG0084	hydrolase, TatD family'
FY149_RS16015	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY149_RS16025	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY149_RS16080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY149_RS16085	COG2095	MarC family integral membrane protein
FY149_RS16090	COG0617	tRNA 3'-terminal CCA addition
FY149_RS16090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY149_RS16090	COG0517	IMP dehydrogenase activity
FY149_RS16100	COG0629	single-stranded DNA binding
FY149_RS16105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY149_RS16115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY149_RS16135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY149_RS16140	COG1121	(ABC) transporter
FY149_RS16160	COG0667	Aldo Keto reductase
FY149_RS16170	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY149_RS16250	COG2239	Acts as a magnesium transporter
FY149_RS16255	COG0243	molybdopterin cofactor binding
FY149_RS16265	COG0242	peptide deformylase activity
FY149_RS16280	COG2205	protein histidine kinase activity
FY149_RS16280	COG2202	Pas domain
FY149_RS16290	COG0321	lipoyl(octanoyl) transferase activity
FY149_RS16295	COG1064	alcohol dehydrogenase
FY149_RS16325	COG1862	Preprotein translocase
FY149_RS16345	COG2124	cytochrome p450
FY149_RS16360	COG0596	Alpha beta hydrolase
FY149_RS16370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY149_RS16375	COG0626	cystathionine gamma-synthase activity
FY149_RS16380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS16385	COG4597	amino acid ABC transporter
FY149_RS16390	COG0765	amino acid transport
FY149_RS16395	COG1126	abc transporter atp-binding protein
FY149_RS16410	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY149_RS16425	COG0436	Aminotransferase
FY149_RS16455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY149_RS16465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY149_RS16470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY149_RS16475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY149_RS16490	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY149_RS16495	COG1489	DNA binding
FY149_RS16500	COG0024	Methionine aminopeptidase
FY149_RS16505	COG2003	Belongs to the UPF0758 family
FY149_RS16520	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY149_RS16545	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY149_RS16550	COG0546	phosphoglycolate phosphatase activity
FY149_RS16560	COG0114	fumarate hydratase activity
FY149_RS16570	COG0504	CTP synthase activity
FY149_RS16580	COG0149	triose-phosphate isomerase activity
FY149_RS16590	COG0187	DNA topoisomerase II activity
FY149_RS16600	COG0740	serine-type endopeptidase activity
FY149_RS16610	COG0640	Transcriptional regulator
FY149_RS16615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY149_RS16620	COG0745	RESPONSE REGULATOR receiver
FY149_RS16635	COG3264	Mechanosensitive ion channel
FY149_RS16635	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY149_RS16700	COG1127	ABC transporter
FY149_RS16705	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY149_RS16710	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_RS16720	COG0280	phosphate acetyltransferase
FY149_RS16720	COG0281	malic enzyme
FY149_RS16730	COG0778	Nitroreductase
FY149_RS16735	COG0823	Involved in the tonB-independent uptake of proteins
FY149_RS16750	COG1368	sulfuric ester hydrolase activity
FY149_RS16775	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY149_RS16795	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY149_RS16815	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY149_RS16830	COG0318	PFAM AMP-dependent synthetase and ligase
FY149_RS16840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY149_RS16840	COG0512	Glutamine amidotransferase of anthranilate synthase
FY149_RS16845	COG0343	queuine tRNA-ribosyltransferase activity
FY149_RS16850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY149_RS16865	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY149_RS16885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY149_RS16890	COG0134	indole-3-glycerol-phosphate synthase activity
FY149_RS16895	COG0315	cyclic pyranopterin monophosphate synthase activity
FY149_RS16900	COG0303	'Molybdopterin
FY149_RS16905	COG3706	GGDEF domain
FY149_RS16915	COG0475	glutathione-regulated potassium exporter activity
FY149_RS16915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY149_RS16925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY149_RS16935	COG2814	Major facilitator Superfamily
FY149_RS16940	COG0746	molybdenum cofactor guanylyltransferase activity
FY149_RS16945	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY149_RS16950	COG0739	heme binding
FY149_RS16955	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY149_RS16960	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY149_RS16965	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY149_RS16970	COG0805	protein transport
FY149_RS16975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY149_RS16980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY149_RS16985	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY149_RS16990	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY149_RS16995	COG1472	Belongs to the glycosyl hydrolase 3 family
FY149_RS17005	COG0018	arginyl-trna synthetase
FY149_RS17010	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY149_RS17035	COG0525	valine-tRNA ligase activity
FY149_RS17045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY149_RS17185	COG1525	nuclease
FY149_RS17260	COG3567	Phage-associated protein, HI1409 family
FY149_RS17315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY149_RS17500	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY149_RS17505	COG1546	Belongs to the CinA family
FY149_RS17505	COG1058	Belongs to the CinA family
FY149_RS17510	COG0589	response to stress
FY149_RS17515	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY149_RS17530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY149_RS17540	COG0640	Transcriptional regulator
FY149_RS17545	COG1914	H( )-stimulated, divalent metal cation uptake system
FY149_RS17555	COG1132	(ABC) transporter
FY149_RS17560	COG0628	permease
FY149_RS17595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY149_RS17605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY149_RS17615	COG0302	gtp cyclohydrolase
FY149_RS17620	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY149_RS17625	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY149_RS17635	COG0516	GMP reductase activity
FY149_RS17635	COG0517	IMP dehydrogenase activity
FY149_RS17670	COG1760	l-serine dehydratase
FY149_RS17710	COG0583	DNA-binding transcription factor activity
FY149_RS17725	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY149_RS17725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY149_RS17735	COG0347	Belongs to the P(II) protein family
FY149_RS17740	COG0174	glutamine synthetase
FY149_RS17770	COG0697	spore germination
FY149_RS17780	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY149_RS17790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY149_RS17820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY149_RS17830	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY149_RS17835	COG2186	Transcriptional regulator
FY149_RS17845	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY149_RS17850	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY149_RS17855	COG3845	ABC transporter
FY149_RS17860	COG1183	phosphatidylcholine synthase activity
FY149_RS17865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY149_RS17870	COG0679	Auxin Efflux Carrier
FY149_RS17875	COG0785	Cytochrome C biogenesis protein
FY149_RS17895	COG1278	Cold shock
FY149_RS17950	COG0577	efflux transmembrane transporter activity
FY149_RS17950	COG1136	(ABC) transporter
FY149_RS17955	COG0577	efflux transmembrane transporter activity
FY149_RS17955	COG1136	(ABC) transporter
FY149_RS17980	COG2151	metal-sulfur cluster biosynthetic enzyme
FY149_RS17985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY149_RS17990	COG0719	Fe-S assembly protein
FY149_RS17995	COG0396	ATPase activity
FY149_RS18000	COG0719	Fe-S assembly protein
FY149_RS18005	COG1104	cysteine desulfurase activity
FY149_RS18010	COG2945	thiolester hydrolase activity
FY149_RS18015	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY149_RS18020	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY149_RS18030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY149_RS18035	COG2833	Protein of unknown function (DUF455)
FY149_RS18040	COG0739	heme binding
FY149_RS18045	COG0513	Belongs to the DEAD box helicase family
FY149_RS18070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY149_RS18080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY149_RS18085	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY149_RS18090	COG0047	phosphoribosylformylglycinamidine synthase activity
FY149_RS18105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY149_RS18110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY149_RS18130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY149_RS18135	COG2814	Major facilitator Superfamily
FY149_RS18140	COG0483	inositol monophosphate 1-phosphatase activity
FY149_RS18145	COG0483	inositol monophosphate 1-phosphatase activity
FY149_RS18150	COG0037	tRNA processing
FY149_RS18155	COG2066	Belongs to the glutaminase family
FY149_RS18160	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY149_RS18165	COG0861	Integral membrane protein TerC family
FY149_RS18180	COG1280	lysine exporter protein (LysE YggA)
FY149_RS18190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY149_RS18195	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY149_RS18205	COG0538	isocitrate dehydrogenase activity
FY149_RS18215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY149_RS18220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY149_RS18225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_RS18230	COG2313	pseudouridylate synthase activity
FY149_RS18240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS18245	COG4215	(ABC) transporter
FY149_RS18255	COG5425	PFAM Usg family protein
FY149_RS18265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY149_RS18270	COG1522	sequence-specific DNA binding
FY149_RS18275	COG1573	uracil-dna glycosylase
FY149_RS18285	COG2205	protein histidine kinase activity
FY149_RS18285	COG2202	Pas domain
FY149_RS18290	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY149_RS18295	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY149_RS18300	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY149_RS18315	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY149_RS18320	COG0842	Transport permease protein
FY149_RS18325	COG1131	(ABC) transporter
FY149_RS18330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY149_RS18330	COG0730	response to heat
FY149_RS18350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY149_RS18355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY149_RS18375	COG0129	dihydroxy-acid dehydratase activity
FY149_RS18380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY149_RS18385	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY149_RS18395	COG3739	integral membrane protein
FY149_RS18400	COG0203	ribosomal protein L17
FY149_RS18405	COG0202	RNA polymerase activity
FY149_RS18410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY149_RS18415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY149_RS18420	COG0563	adenylate kinase activity
FY149_RS18425	COG0201	protein transport
FY149_RS18430	COG0200	Binds to the 23S rRNA
FY149_RS18435	COG1841	ribosomal large subunit assembly
FY149_RS18440	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY149_RS18445	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY149_RS18450	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY149_RS18455	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY149_RS18460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY149_RS18465	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY149_RS18470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY149_RS18475	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY149_RS18480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY149_RS18485	COG0255	Belongs to the universal ribosomal protein uL29 family
FY149_RS18490	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY149_RS18495	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY149_RS18500	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY149_RS18505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY149_RS18510	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY149_RS18515	COG0089	rRNA binding
FY149_RS18520	COG0088	Forms part of the polypeptide exit tunnel
FY149_RS18525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY149_RS18530	COG0051	transcription antitermination factor activity, RNA binding
FY149_RS18535	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY149_RS18540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY149_RS18545	COG0049	tRNA binding
FY149_RS18550	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY149_RS18570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY149_RS18575	COG0085	RNA polymerase activity
FY149_RS18580	COG0222	ribosome binding
FY149_RS18585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY149_RS18590	COG0081	regulation of translation
FY149_RS18595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY149_RS18605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY149_RS18615	COG1086	Polysaccharide biosynthesis protein
FY149_RS18620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY149_RS18625	COG0861	Integral membrane protein TerC family
FY149_RS18630	COG3895	Periplasmic Protein
FY149_RS18650	COG1132	(ABC) transporter
FY149_RS18655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY149_RS18675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY149_RS18710	COG2205	protein histidine kinase activity
FY149_RS18710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS18710	COG0784	Response regulator, receiver
FY149_RS18710	COG2198	Histidine kinase
FY149_RS18715	COG0784	Response regulator, receiver
FY149_RS18720	COG2202	Pas domain
FY149_RS18720	COG3920	Histidine kinase
FY149_RS18725	COG0784	Response regulator, receiver
FY149_RS18730	COG4251	negative regulation of phosphorylation
FY149_RS18745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY149_RS18750	COG1607	acyl-coa hydrolase
FY149_RS18770	COG2910	NAD(P)H-binding
FY149_RS18775	COG1733	regulation of RNA biosynthetic process
FY149_RS18790	COG0556	nucleotide-excision repair
FY149_RS18800	COG2382	esterase
FY149_RS18820	COG0484	heat shock protein binding
FY149_RS19135	COG3706	GGDEF domain
FY149_RS19155	COG1840	ABC-type Fe3 transport system, periplasmic component
FY149_RS19160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY149_RS19175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY149_RS19185	COG2207	Transcriptional regulator
FY149_RS19190	COG1064	alcohol dehydrogenase
FY149_RS19195	COG1252	NADH dehydrogenase
FY149_RS19200	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY149_RS19205	COG2197	response regulator
FY149_RS19210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY149_RS19245	COG0656	L-ascorbic acid biosynthetic process
FY149_RS19260	COG0440	acetolactate synthase activity
FY149_RS19265	COG0028	Belongs to the TPP enzyme family
FY149_RS19275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY149_RS19280	COG0560	Phosphoserine phosphatase
FY149_RS19280	COG3830	Belongs to the UPF0237 family
FY149_RS19300	COG0330	HflC and HflK could
FY149_RS19305	COG0330	HflC and HflK could
FY149_RS19315	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY149_RS19350	COG0277	FAD linked oxidase domain protein
FY149_RS19355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY149_RS19395	COG1335	isochorismatase
FY149_RS19425	COG2264	protein methyltransferase activity
FY149_RS19430	COG1999	signal sequence binding
FY149_RS19440	COG0835	chemotaxis
FY149_RS19450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY149_RS19455	COG0583	DNA-binding transcription factor activity
FY149_RS19465	COG1247	-acetyltransferase
FY149_RS19475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY149_RS19480	COG0497	DNA recombination
FY149_RS19485	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY149_RS19495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY149_RS19500	COG0849	cell division
FY149_RS19505	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY149_RS19510	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY149_RS19515	COG0477	Major facilitator Superfamily
FY149_RS19520	COG5001	Diguanylate cyclase
FY149_RS19525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY149_RS19530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY149_RS19535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY149_RS19545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY149_RS19550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY149_RS19560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY149_RS19575	COG0275	rRNA processing
FY149_RS19580	COG2001	Belongs to the MraZ family
FY149_RS19605	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY149_RS19635	COG4106	trans-aconitate 2-methyltransferase activity
FY149_RS19655	COG2226	methyltransferase
FY149_RS19665	COG2267	carboxylic ester hydrolase activity
FY149_RS19670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY149_RS19685	COG0251	oxidation-reduction process
FY149_RS19700	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_RS19705	COG2814	Major facilitator Superfamily
FY149_RS19735	COG1012	belongs to the aldehyde dehydrogenase family
FY149_RS19740	COG0174	glutamine synthetase
FY149_RS19745	COG0531	amino acid
FY149_RS19755	COG1737	Transcriptional regulator
FY149_RS19760	COG2182	Extracellular solute-binding protein
FY149_RS19775	COG3842	ATPase activity
FY149_RS19835	COG2968	Membrane
FY149_RS19845	COG0432	Pfam Uncharacterised protein family UPF0047
FY149_RS19860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY149_RS19865	COG0358	DNA primase activity
FY149_RS19885	COG0505	Belongs to the CarA family
FY149_RS19890	COG0534	Mate efflux family protein
FY149_RS19905	COG2321	neutral zinc metallopeptidase
FY149_RS19920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY149_RS19930	COG3706	GGDEF domain
FY149_RS19945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY149_RS19955	COG1522	sequence-specific DNA binding
FY149_RS19960	COG0492	ferredoxin-NADP+ reductase activity
FY149_RS19965	COG0583	DNA-binding transcription factor activity
FY149_RS19975	COG1902	pentaerythritol trinitrate reductase activity
FY149_RS20000	COG0387	Pfam Sodium calcium exchanger
FY149_RS20005	COG0436	Aminotransferase
FY149_RS20010	COG2199	diguanylate cyclase activity
FY149_RS20010	COG2200	EAL domain
FY149_RS20025	COG1278	Cold shock
FY149_RS20030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY149_RS20040	COG1846	Transcriptional regulator
FY149_RS20045	COG0745	RESPONSE REGULATOR receiver
FY149_RS20055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY149_RS20075	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY149_RS20085	COG1496	oxidoreductase activity
FY149_RS20100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY149_RS20110	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY149_RS20125	COG0840	transmembrane signaling receptor activity
FY149_RS20130	COG1012	belongs to the aldehyde dehydrogenase family
FY149_RS20135	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY149_RS20140	COG5001	Diguanylate cyclase
FY149_RS20140	COG3300	MHYT domain
FY149_RS20145	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY149_RS20150	COG5001	Diguanylate cyclase
FY149_RS20160	COG0193	aminoacyl-tRNA hydrolase activity
FY149_RS20170	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY149_RS20195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY149_RS20205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY149_RS20205	COG2857	Cytochrome c1
FY149_RS20225	COG1132	(ABC) transporter
FY149_RS20235	COG1132	(ABC) transporter
FY149_RS20245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY149_RS20260	COG0408	coproporphyrinogen oxidase activity
FY149_RS20275	COG0617	tRNA 3'-terminal CCA addition
FY149_RS20290	COG0714	Associated with various cellular activities
FY149_RS20310	COG0454	-acetyltransferase
FY149_RS20325	COG0477	Major facilitator Superfamily
FY149_RS20335	COG0435	Glutathione S-transferase
FY149_RS20340	COG0494	nUDIX hydrolase
FY149_RS20350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY149_RS20355	COG3135	benzoate transporter
FY149_RS20380	COG0740	serine-type endopeptidase activity
FY149_RS20395	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY149_RS20400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY149_RS20425	COG4175	Glycine betaine
FY149_RS20445	COG1435	thymidine kinase activity
FY149_RS20470	COG1629	transport
FY149_RS20470	COG4771	TonB-dependent receptor
FY149_RS20480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY149_RS20480	COG0512	Glutamine amidotransferase of anthranilate synthase
FY149_RS20495	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY149_RS20505	COG0366	Alpha amylase catalytic
FY149_RS20510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_RS20530	COG1160	GTP binding
FY149_RS20550	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY149_RS20560	COG0024	Methionine aminopeptidase
FY149_RS20570	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS20590	COG0583	DNA-binding transcription factor activity
FY149_RS20605	COG0402	S-adenosylhomocysteine deaminase activity
FY149_RS20615	COG1304	FMN binding
FY149_RS20625	COG1309	transcriptional regulator
FY149_RS20630	COG1686	Belongs to the peptidase S11 family
FY149_RS20640	COG2351	hydroxyisourate hydrolase activity
FY149_RS20645	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY149_RS20670	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY149_RS20680	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY149_RS20680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS20690	COG0513	Belongs to the DEAD box helicase family
FY149_RS20700	COG2259	Doxx family
FY149_RS20705	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_RS20715	COG2308	Evidence 4 Homologs of previously reported genes of
FY149_RS20725	COG1305	Transglutaminase-like
FY149_RS20750	COG4214	carbohydrate transport
FY149_RS20760	COG4213	ABC transporter substrate-binding protein
FY149_RS20815	COG2948	multi-organism process
FY149_RS20825	COG3701	Conjugal transfer protein
FY149_RS20830	COG3846	protein secretion by the type IV secretion system
FY149_RS20845	COG3451	type IV secretory pathway VirB4
FY149_RS20860	COG4962	Type ii secretion system protein e
FY149_RS20885	COG0583	DNA-binding transcription factor activity
FY149_RS20895	COG1566	PFAM secretion protein HlyD family protein
FY149_RS20910	COG2207	Transcriptional regulator
FY149_RS20915	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS20925	COG0583	DNA-binding transcription factor activity
FY149_RS20935	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY149_RS20950	COG0583	DNA-binding transcription factor activity
FY149_RS20985	COG1192	Involved in chromosome partitioning
FY149_RS21025	COG2814	Major facilitator Superfamily
FY149_RS21035	COG5489	Protein of unknown function (DUF736)
FY149_RS21055	COG3012	SEC-C Motif Domain Protein
FY149_RS21085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY149_RS21115	COG1204	response to ionizing radiation
FY149_RS21130	COG0514	ATP-dependent DNA helicase (RecQ)
FY149_RS21180	COG0583	DNA-binding transcription factor activity
FY149_RS21185	COG1902	pentaerythritol trinitrate reductase activity
FY149_RS21190	COG0583	DNA-binding transcription factor activity
FY149_RS21205	COG1335	isochorismatase
FY149_RS21210	COG0583	DNA-binding transcription factor activity
FY149_RS21215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY149_RS21225	COG4584	PFAM Integrase catalytic
FY149_RS21240	COG0840	transmembrane signaling receptor activity
FY149_RS21255	COG1410	methionine synthase
FY149_RS21255	COG0646	methionine synthase
FY149_RS21270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS21300	COG1215	transferase activity, transferring glycosyl groups
FY149_RS21330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY149_RS21345	COG2346	COG2346, Truncated hemoglobins
FY149_RS21365	COG1309	transcriptional regulator
FY149_RS21380	COG0494	nUDIX hydrolase
FY149_RS21390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_RS21395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_RS21425	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY149_RS21430	COG0830	nickel cation binding
FY149_RS21435	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY149_RS21450	COG0804	urea catabolic process
FY149_RS21455	COG1442	glycosyl transferase family 8
FY149_RS21460	COG3755	Protein conserved in bacteria
FY149_RS21470	COG0832	Belongs to the urease beta subunit family
FY149_RS21475	COG3813	Protein conserved in bacteria
FY149_RS21480	COG0831	urea catabolic process
FY149_RS21485	COG0829	nickel cation binding
FY149_RS21515	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY149_RS21535	COG0174	glutamine synthetase
FY149_RS21540	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS21545	COG2198	Histidine kinase
FY149_RS21545	COG0784	Response regulator, receiver
FY149_RS21545	COG5002	protein histidine kinase activity
FY149_RS21560	COG0726	polysaccharide deacetylase
FY149_RS21595	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY149_RS21670	COG0564	pseudouridine synthase activity
FY149_RS21680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY149_RS21690	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY149_RS21715	COG0346	lactoylglutathione lyase activity
FY149_RS21725	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY149_RS21735	COG2832	Protein of unknown function (DUF454)
FY149_RS21740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY149_RS21745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_RS21750	COG4558	Periplasmic binding protein
FY149_RS21760	COG3721	Heme iron utilization protein
FY149_RS21775	COG3655	Transcriptional regulator
FY149_RS21800	COG2205	protein histidine kinase activity
FY149_RS21840	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_RS21845	COG4605	iron ion homeostasis
FY149_RS21850	COG4604	ABC transporter, ATP-binding protein
FY149_RS21855	COG0783	Belongs to the Dps family
FY149_RS21870	COG0840	transmembrane signaling receptor activity
FY149_RS21870	COG2972	Histidine kinase
FY149_RS21875	COG0656	L-ascorbic acid biosynthetic process
FY149_RS21880	COG2814	Major facilitator Superfamily
FY149_RS21890	COG0583	DNA-binding transcription factor activity
FY149_RS21895	COG0657	acetylesterase activity
FY149_RS21900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_RS21920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY149_RS21925	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY149_RS21930	COG0288	reversible hydration of carbon dioxide
FY149_RS21940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY149_RS21960	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY149_RS21965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY149_RS21970	COG0778	Nitroreductase
FY149_RS21975	COG2267	carboxylic ester hydrolase activity
FY149_RS21980	COG0251	oxidation-reduction process
FY149_RS21985	COG1335	isochorismatase
FY149_RS21990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS22000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_RS22015	COG1175	transmembrane transport
FY149_RS22020	COG0395	ABC-type sugar transport system, permease component
FY149_RS22025	COG3842	ATPase activity
FY149_RS22030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_RS22040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY149_RS22055	COG4608	Belongs to the ABC transporter superfamily
FY149_RS22060	COG0444	Belongs to the ABC transporter superfamily
FY149_RS22065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS22070	COG0601	transmembrane transport
FY149_RS22125	COG2159	amidohydrolase
FY149_RS22130	COG1960	acyl-CoA dehydrogenase activity
FY149_RS22160	COG0745	RESPONSE REGULATOR receiver
FY149_RS22170	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY149_RS22170	COG1902	pentaerythritol trinitrate reductase activity
FY149_RS22175	COG3842	ATPase activity
FY149_RS22185	COG1840	ABC-type Fe3 transport system, periplasmic component
FY149_RS22190	COG1840	ABC-type Fe3 transport system, periplasmic component
FY149_RS22195	COG0745	RESPONSE REGULATOR receiver
FY149_RS22205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY149_RS22210	COG0583	DNA-binding transcription factor activity
FY149_RS22215	COG1278	Cold shock
FY149_RS22255	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY149_RS22260	COG1309	transcriptional regulator
FY149_RS22265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_RS22270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY149_RS22280	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY149_RS22285	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY149_RS22305	COG0583	DNA-binding transcription factor activity
FY149_RS22310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS22315	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY149_RS22320	COG4149	molybdate abc transporter
FY149_RS22325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY149_RS22340	COG2022	thiamine diphosphate biosynthetic process
FY149_RS22355	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY149_RS22360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY149_RS22370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY149_RS22390	COG1132	(ABC) transporter
FY149_RS22395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY149_RS22440	COG4166	transmembrane transport
FY149_RS22445	COG0601	transmembrane transport
FY149_RS22450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS22465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY149_RS22470	COG3142	Participates in the control of copper homeostasis
FY149_RS22475	COG2814	Major facilitator Superfamily
FY149_RS22490	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS22495	COG1737	Transcriptional regulator
FY149_RS22505	COG3842	ATPase activity
FY149_RS22515	COG0395	ABC-type sugar transport system, permease component
FY149_RS22535	COG2188	Transcriptional regulator
FY149_RS22540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY149_RS22545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY149_RS22550	COG1940	carbohydrate kinase activity
FY149_RS22560	COG0671	phosphoesterase, PA-phosphatase related
FY149_RS22565	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY149_RS22570	COG0156	8-amino-7-oxononanoate synthase activity
FY149_RS22580	COG0729	surface antigen
FY149_RS22590	COG0835	chemotaxis
FY149_RS22600	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY149_RS22605	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY149_RS22610	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY149_RS22615	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY149_RS22620	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY149_RS22625	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY149_RS22640	COG4974	Belongs to the 'phage' integrase family
FY149_RS22665	COG1280	lysine exporter protein (LysE YggA)
FY149_RS22675	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY149_RS22680	COG0567	Dehydrogenase, E1 component
FY149_RS22685	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY149_RS22690	COG0045	succinate-CoA ligase (ADP-forming) activity
FY149_RS22695	COG0039	L-malate dehydrogenase activity
FY149_RS22700	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY149_RS22750	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY149_RS22755	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY149_RS22760	COG0181	hydroxymethylbilane synthase activity
FY149_RS22800	COG1872	DUF167
FY149_RS22805	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY149_RS22815	COG1217	gtp-binding protein TYPA
FY149_RS22820	COG0339	signal peptide processing
FY149_RS22825	COG1846	Transcriptional regulator
FY149_RS22835	COG0137	argininosuccinate synthase activity
FY149_RS22845	COG1280	lysine exporter protein (LysE YggA)
FY149_RS22850	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY149_RS22855	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY149_RS22865	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY149_RS22880	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY149_RS22885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY149_RS22890	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY149_RS22900	COG4181	ATPase activity
FY149_RS22910	COG0670	Belongs to the BI1 family
FY149_RS22925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY149_RS22930	COG4133	protoheme IX ABC transporter activity
FY149_RS22935	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY149_RS22940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY149_RS22965	COG2917	probably involved in intracellular septation
FY149_RS22970	COG0552	protein localization to endoplasmic reticulum
FY149_RS22975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY149_RS22980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY149_RS22995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY149_RS23000	COG0287	Prephenate dehydrogenase
FY149_RS23000	COG1605	Chorismate mutase
FY149_RS23005	COG0228	four-way junction DNA binding
FY149_RS23010	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY149_RS23015	COG0336	Belongs to the RNA methyltransferase TrmD family
FY149_RS23025	COG0335	large ribosomal subunit rRNA binding
FY149_RS23030	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY149_RS23035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_RS23050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY149_RS23070	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY149_RS23090	COG0488	(ABC) transporter
FY149_RS23100	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY149_RS23110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY149_RS23115	COG0142	geranyltranstransferase activity
FY149_RS23120	COG2885	chlorophyll binding
FY149_RS23125	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY149_RS23130	COG2223	nitrite transmembrane transporter activity
FY149_RS23135	COG1349	DNA-binding transcription factor activity
FY149_RS23140	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY149_RS23145	COG2197	response regulator
FY149_RS23150	COG1132	(ABC) transporter
FY149_RS23160	COG3459	Glycosyltransferase 36 associated
FY149_RS23165	COG1473	amidohydrolase
FY149_RS23175	COG0579	oxidoreductase
FY149_RS23185	COG0129	dihydroxy-acid dehydratase activity
FY149_RS23190	COG2084	Dehydrogenase
FY149_RS23195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_RS23200	COG0277	FAD linked oxidase domain protein
FY149_RS23205	COG2186	Transcriptional regulator
FY149_RS23215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY149_RS23220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY149_RS23225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY149_RS23230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY149_RS23240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY149_RS23245	COG0495	leucyl-tRNA aminoacylation
FY149_RS23260	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY149_RS23265	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY149_RS23280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY149_RS23285	COG1946	Acyl-CoA thioesterase
FY149_RS23290	COG0347	Belongs to the P(II) protein family
FY149_RS23295	COG0004	ammonium transporteR
FY149_RS23300	COG1674	ftsk spoiiie
FY149_RS23305	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY149_RS23320	COG0745	RESPONSE REGULATOR receiver
FY149_RS23330	COG1329	Transcriptional regulator
FY149_RS23340	COG2270	Major facilitator Superfamily
FY149_RS23355	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS23370	COG0494	nUDIX hydrolase
FY149_RS23375	COG2861	carbohydrate metabolic process
FY149_RS23380	COG0793	Belongs to the peptidase S41A family
FY149_RS23390	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY149_RS23395	COG0799	negative regulation of ribosome biogenesis
FY149_RS23400	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY149_RS23405	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY149_RS23410	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY149_RS23415	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY149_RS23430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY149_RS23435	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY149_RS23460	COG0066	3-isopropylmalate dehydratase activity
FY149_RS23465	COG0473	3-isopropylmalate dehydrogenase activity
FY149_RS23470	COG1858	cytochrome C peroxidase
FY149_RS23475	COG1797	cobyrinic acid a,c-diamide synthase activity
FY149_RS23485	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY149_RS23550	COG1492	cobalamin metabolic process
FY149_RS23565	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_RS23570	COG3254	rhamnose metabolic process
FY149_RS23575	COG0246	Mannitol dehydrogenase
FY149_RS23580	COG1063	alcohol dehydrogenase
FY149_RS23605	COG1129	ABC transporter
FY149_RS23610	COG2186	Transcriptional regulator
FY149_RS23615	COG2721	sulfolactate sulfo-lyase activity
FY149_RS23620	COG0138	bifunctional purine biosynthesis protein purh
FY149_RS23630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY149_RS23630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY149_RS23635	COG0501	Belongs to the peptidase M48B family
FY149_RS23655	COG0357	Ribosomal RNA small subunit methyltransferase G
FY149_RS23660	COG0445	tRNA wobble uridine modification
FY149_RS23665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY149_RS23670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY149_RS23675	COG1981	membrane
FY149_RS23680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY149_RS23685	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY149_RS23690	COG0424	maF-like protein
FY149_RS23695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY149_RS23700	COG0237	dephospho-CoA kinase activity
FY149_RS23710	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY149_RS23715	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY149_RS23725	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY149_RS23750	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY149_RS23765	COG0135	phosphoribosylanthranilate isomerase activity
FY149_RS23770	COG0133	tryptophan synthase activity
FY149_RS23775	COG0159	tryptophan synthase activity
FY149_RS23780	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY149_RS23795	COG1074	ATP-dependent DNA helicase activity
FY149_RS23805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY149_RS23810	COG0802	atpase or kinase
FY149_RS23815	COG2205	protein histidine kinase activity
FY149_RS23820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY149_RS23825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY149_RS23830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY149_RS23830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY149_RS23835	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY149_RS23840	COG0642	Histidine kinase
FY149_RS23845	COG0745	RESPONSE REGULATOR receiver
FY149_RS23850	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY149_RS23860	COG1652	LysM domain
FY149_RS23865	COG1072	(Pantothenic acid kinase))
FY149_RS23870	COG0140	phosphoribosyl-ATP diphosphatase activity
FY149_RS23875	COG0107	imidazoleglycerol-phosphate synthase activity
FY149_RS23880	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY149_RS23885	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY149_RS23895	COG0131	Imidazoleglycerol-phosphate dehydratase
FY149_RS23900	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY149_RS23905	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY149_RS23915	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY149_RS23930	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY149_RS23940	COG1643	Atp-dependent helicase
FY149_RS23985	COG1940	carbohydrate kinase activity
FY149_RS24005	COG1072	(Pantothenic acid kinase))
FY149_RS24015	COG1780	Probably involved in ribonucleotide reductase function
FY149_RS24035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY149_RS24065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_RS24075	COG2813	Specifically methylates the guanine in position
FY149_RS24080	COG1185	polyribonucleotide nucleotidyltransferase activity
FY149_RS24085	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY149_RS24090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY149_RS24095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY149_RS24100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY149_RS24100	COG3064	Membrane
FY149_RS24115	COG0779	Required for maturation of 30S ribosomal subunits
FY149_RS24120	COG2814	Major facilitator Superfamily
FY149_RS24130	COG2951	lytic endotransglycosylase activity
FY149_RS24135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY149_RS24145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY149_RS24150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY149_RS24165	COG2816	NAD+ diphosphatase activity
FY149_RS24170	COG0077	Prephenate dehydratase
FY149_RS24170	COG1605	Chorismate mutase
FY149_RS24175	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY149_RS24180	COG3474	cytochrome
FY149_RS24190	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY149_RS24195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY149_RS24200	COG1278	Cold shock
FY149_RS24205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY149_RS24215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY149_RS24215	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY149_RS24220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY149_RS24250	COG2900	Belongs to the SlyX family
FY149_RS24260	COG0484	heat shock protein binding
FY149_RS24265	COG0443	Heat shock 70 kDa protein
FY149_RS24280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY149_RS24285	COG1744	ABC transporter substrate-binding protein PnrA-like
FY149_RS24290	COG3845	ABC transporter
FY149_RS24295	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY149_RS24300	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY149_RS24305	COG0295	cytidine deaminase activity
FY149_RS24310	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY149_RS24315	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY149_RS24320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY149_RS24330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY149_RS24335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY149_RS24340	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY149_RS24350	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY149_RS24355	COG1845	cytochrome c oxidase, subunit III
FY149_RS24360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY149_RS24365	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY149_RS24370	COG0477	Major facilitator Superfamily
FY149_RS24375	COG0067	glutamate synthase
FY149_RS24375	COG0069	glutamate synthase activity
FY149_RS24375	COG0070	glutamate synthase
FY149_RS24380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY149_RS24395	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY149_RS24405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY149_RS24435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_RS24455	COG0848	biopolymer transport protein
FY149_RS24465	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY149_RS24480	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY149_RS24485	COG3454	Phosphonate metabolism
FY149_RS24490	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY149_RS24495	COG3639	organic phosphonate transmembrane transporter activity
FY149_RS24500	COG3639	organic phosphonate transmembrane transporter activity
FY149_RS24510	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY149_RS24520	COG4778	phosphonate C-P lyase system protein PhnL
FY149_RS24525	COG4107	phosphonate C-P lyase system protein PhnK
FY149_RS24530	COG3627	carbon phosphorus lyase activity
FY149_RS24535	COG3626	phosphonate metabolism
FY149_RS24540	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY149_RS24545	COG3624	Phosphonate C-P lyase system protein PhnG
FY149_RS24550	COG2188	Transcriptional regulator
FY149_RS24555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY149_RS24560	COG0837	glucose binding
FY149_RS24565	COG1803	Methylglyoxal synthase
FY149_RS24570	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY149_RS24575	COG4166	transmembrane transport
FY149_RS24580	COG4174	ABC transporter (Permease)
FY149_RS24585	COG4239	(ABC) transporter, permease
FY149_RS24590	COG4172	Belongs to the ABC transporter superfamily
FY149_RS24595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS24600	COG0174	glutamine synthetase
FY149_RS24605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_RS24610	COG3265	gluconokinase activity
FY149_RS24615	COG1174	glycine betaine transport
FY149_RS24620	COG1125	glycine betaine transport
FY149_RS24625	COG1174	glycine betaine transport
FY149_RS24630	COG1732	Glycine betaine
FY149_RS24640	COG1959	2 iron, 2 sulfur cluster binding
FY149_RS24645	COG1840	ABC-type Fe3 transport system, periplasmic component
FY149_RS24655	COG4269	membrane
FY149_RS24670	COG0697	spore germination
FY149_RS24685	COG0791	NLP P60 protein
FY149_RS24695	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY149_RS24700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY149_RS24735	COG4964	Belongs to the GSP D family
FY149_RS24780	COG3422	double-strand break repair
FY149_RS24785	COG3757	hydrolase, family 25
FY149_RS24790	COG0697	spore germination
FY149_RS24795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY149_RS24810	COG0492	ferredoxin-NADP+ reductase activity
FY149_RS24825	COG0481	GTPase activity
FY149_RS24830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY149_RS24845	COG1396	sequence-specific DNA binding
FY149_RS24860	COG1917	Cupin 2, conserved barrel domain protein
FY149_RS24860	COG2169	Transcriptional regulator
FY149_RS24865	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY149_RS24890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY149_RS24895	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY149_RS24900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY149_RS24910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY149_RS24915	COG0072	phenylalanine-tRNA ligase activity
FY149_RS24915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY149_RS24920	COG0667	Aldo Keto reductase
FY149_RS24940	COG4977	sequence-specific DNA binding
FY149_RS24965	COG1570	exodeoxyribonuclease VII activity
FY149_RS24970	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_RS24980	COG1846	Transcriptional regulator
FY149_RS24990	COG2309	aminopeptidase activity
FY149_RS25000	COG1393	Belongs to the ArsC family
FY149_RS25020	COG1309	transcriptional regulator
FY149_RS25030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY149_RS25030	COG0519	Catalyzes the synthesis of GMP from XMP
FY149_RS25045	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY149_RS25075	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY149_RS25085	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY149_RS25095	COG1968	undecaprenyl-diphosphatase activity
FY149_RS25110	COG0284	orotidine-5'-phosphate decarboxylase activity
FY149_RS25120	COG3963	phosphatidate phosphatase activity
FY149_RS25130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY149_RS25135	COG0792	nuclease activity
FY149_RS25150	COG1175	transmembrane transport
FY149_RS25155	COG0395	ABC-type sugar transport system, permease component
FY149_RS25160	COG3842	ATPase activity
FY149_RS25170	COG0189	ligase activity
FY149_RS25180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY149_RS25185	COG1280	lysine exporter protein (LysE YggA)
FY149_RS25190	COG0756	dUTP diphosphatase activity
FY149_RS25195	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY149_RS25200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY149_RS25215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY149_RS25220	COG2226	methyltransferase
FY149_RS25225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY149_RS25230	COG1024	Enoyl-CoA hydratase
FY149_RS25235	COG0268	Binds directly to 16S ribosomal RNA
FY149_RS25240	COG1192	Involved in chromosome partitioning
FY149_RS25245	COG1475	DNA binding
FY149_RS25250	COG0640	Transcriptional regulator
FY149_RS25265	COG1126	abc transporter atp-binding protein
FY149_RS25275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_RS25280	COG1609	Transcriptional regulator
FY149_RS25315	COG3239	Fatty acid desaturase
FY149_RS25325	COG1278	Cold shock
FY149_RS25405	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY149_RS25405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY149_RS25445	COG4191	Histidine kinase
FY149_RS25460	COG0640	Transcriptional regulator
FY149_RS25490	COG4977	sequence-specific DNA binding
FY149_RS25495	COG2211	Major facilitator Superfamily
FY149_RS25500	COG2807	transmembrane transport
FY149_RS25505	COG1846	Transcriptional regulator
FY149_RS25520	COG2814	Major facilitator Superfamily
FY149_RS25550	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY149_RS25565	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY149_RS25570	COG0583	DNA-binding transcription factor activity
FY149_RS25585	COG0071	Belongs to the small heat shock protein (HSP20) family
FY149_RS25635	COG3838	Conjugal transfer protein Trbc
FY149_RS25640	COG3702	type iv secretory pathway
FY149_RS25645	COG3451	type IV secretory pathway VirB4
FY149_RS25660	COG3704	protein secretion by the type IV secretion system
FY149_RS25670	COG3736	Type IV secretory pathway, component VirB8
FY149_RS25675	COG3504	Conjugal transfer protein
FY149_RS25680	COG2948	multi-organism process
FY149_RS25685	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY149_RS25790	COG3831	ATPase activity
FY149_RS25805	COG3505	Type IV secretory pathway VirD4
FY149_RS25830	COG0583	DNA-binding transcription factor activity
FY149_RS25875	COG0745	RESPONSE REGULATOR receiver
FY149_RS25915	COG3842	ATPase activity
FY149_RS25920	COG4208	sulfate ABC transporter
FY149_RS25925	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_RS25945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY149_RS25950	COG1942	4-Oxalocrotonate Tautomerase
FY149_RS25960	COG3971	2-oxopent-4-enoate hydratase activity
FY149_RS25970	COG1414	Transcriptional regulator
FY149_RS25980	COG1137	ATPase activity
FY149_RS25995	COG4177	L-phenylalanine transmembrane transporter activity
FY149_RS26015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY149_RS26020	COG1175	transmembrane transport
FY149_RS26025	COG0395	ABC-type sugar transport system, permease component
FY149_RS26035	COG0366	Alpha amylase catalytic
FY149_RS26040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY149_RS26045	COG1082	Xylose isomerase domain protein TIM barrel
FY149_RS26050	COG3842	ATPase activity
FY149_RS26060	COG1940	carbohydrate kinase activity
FY149_RS26065	COG0395	ABC-type sugar transport system, permease component
FY149_RS26075	COG2182	Extracellular solute-binding protein
FY149_RS26080	COG0673	inositol 2-dehydrogenase activity
FY149_RS26110	COG1126	abc transporter atp-binding protein
FY149_RS26115	COG0765	amino acid transport
FY149_RS26120	COG0765	amino acid transport
FY149_RS26130	COG4608	Belongs to the ABC transporter superfamily
FY149_RS26140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS26155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY149_RS26160	COG0583	DNA-binding transcription factor activity
FY149_RS26165	COG2423	ornithine cyclodeaminase activity
FY149_RS26175	COG1957	nucleoside hydrolase
FY149_RS26185	COG1309	transcriptional regulator
FY149_RS26195	COG1335	isochorismatase
FY149_RS26200	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS26205	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS26250	COG0583	DNA-binding transcription factor activity
FY149_RS26255	COG1902	pentaerythritol trinitrate reductase activity
FY149_RS26260	COG0583	DNA-binding transcription factor activity
FY149_RS26265	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS26275	COG1335	isochorismatase
FY149_RS26280	COG0583	DNA-binding transcription factor activity
FY149_RS26290	COG1695	Transcriptional regulator
FY149_RS26375	COG2207	Transcriptional regulator
FY149_RS26435	COG1802	Transcriptional regulator
FY149_RS26440	COG3485	protocatechuate 3,4-dioxygenase
FY149_RS26445	COG3971	2-oxopent-4-enoate hydratase activity
FY149_RS26460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY149_RS26465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY149_RS26480	COG1063	alcohol dehydrogenase
FY149_RS26490	COG1960	acyl-CoA dehydrogenase activity
FY149_RS26495	COG1024	Enoyl-CoA hydratase
FY149_RS26505	COG1012	belongs to the aldehyde dehydrogenase family
FY149_RS26510	COG0477	Major facilitator Superfamily
FY149_RS26525	COG3706	GGDEF domain
FY149_RS26545	COG1846	Transcriptional regulator
FY149_RS26585	COG1012	belongs to the aldehyde dehydrogenase family
FY149_RS26595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY149_RS26605	COG3386	PFAM SMP-30 Gluconolaconase
FY149_RS26610	COG3622	Belongs to the hyi family
FY149_RS26615	COG2084	Dehydrogenase
FY149_RS26640	COG1940	carbohydrate kinase activity
FY149_RS26645	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_RS26655	COG1129	ABC transporter
FY149_RS26680	COG0583	DNA-binding transcription factor activity
FY149_RS26685	COG2271	Major facilitator Superfamily
FY149_RS26695	COG2272	Belongs to the type-B carboxylesterase lipase family
FY149_RS26715	COG1129	ABC transporter
FY149_RS26740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY149_RS26750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY149_RS26785	COG0583	DNA-binding transcription factor activity
FY149_RS26790	COG1414	Transcriptional regulator
FY149_RS26800	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_RS26810	COG3842	ATPase activity
FY149_RS26815	COG1175	transmembrane transport
FY149_RS26820	COG0395	ABC-type sugar transport system, permease component
FY149_RS26830	COG0477	Major facilitator Superfamily
FY149_RS26865	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY149_RS26880	COG0583	DNA-binding transcription factor activity
FY149_RS26885	COG0747	negative chemotaxis
FY149_RS26895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS26910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_RS26920	COG4215	(ABC) transporter
FY149_RS26975	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY149_RS26980	COG0251	oxidation-reduction process
FY149_RS27015	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS27020	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_RS27025	COG1335	isochorismatase
FY149_RS27035	COG1309	transcriptional regulator
FY149_RS27040	COG4604	ABC transporter, ATP-binding protein
FY149_RS27045	COG4605	iron ion homeostasis
FY149_RS27050	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_RS27060	COG2132	Multicopper oxidase
FY149_RS27065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY149_RS27115	COG1695	Transcriptional regulator
FY149_RS27150	COG2132	Multicopper oxidase
FY149_RS27185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY149_RS27205	COG1192	Involved in chromosome partitioning
FY149_RS27210	COG1475	DNA binding
FY149_RS27215	COG0640	Transcriptional regulator
FY149_RS27220	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY149_RS27250	COG2211	Major facilitator Superfamily
FY149_RS27295	COG4974	Belongs to the 'phage' integrase family
FY149_RS27300	COG1051	belongs to the nudix hydrolase family
FY149_RS27370	COG3012	SEC-C Motif Domain Protein
FY149_RS27405	COG2824	Alkylphosphonate utilization operon protein PhnA
FY149_RS27425	COG1280	lysine exporter protein (LysE YggA)
FY149_RS27490	COG5489	Protein of unknown function (DUF736)
FY149_RS27580	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY149_RS27595	COG0747	negative chemotaxis
FY149_RS27615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS27620	COG0584	glycerophosphoryl diester phosphodiesterase
FY149_RS27625	COG0483	inositol monophosphate 1-phosphatase activity
FY149_RS27690	COG3161	chorismate lyase activity
FY149_RS27930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_RS27960	COG0583	DNA-binding transcription factor activity
FY149_RS27965	COG0747	negative chemotaxis
FY149_RS27980	COG0252	asparaginase activity
FY149_RS27985	COG0583	DNA-binding transcription factor activity
FY149_RS28005	COG3842	ATPase activity
FY149_RS28030	COG3701	Conjugal transfer protein
FY149_RS28035	COG3846	protein secretion by the type IV secretion system
FY149_RS28045	COG5314	conjugation
FY149_RS28050	COG3451	type IV secretory pathway VirB4
FY149_RS28065	COG4962	Type ii secretion system protein e
FY149_RS28075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY149_RS28110	COG1192	Involved in chromosome partitioning
FY149_RS28120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs