locus-tag	class	description
AVI_RS00020	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AVI_RS00025	COG0424	maF-like protein
AVI_RS00030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVI_RS00035	COG0237	dephospho-CoA kinase activity
AVI_RS00045	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AVI_RS00060	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AVI_RS00100	COG0135	phosphoribosylanthranilate isomerase activity
AVI_RS00105	COG0133	tryptophan synthase activity
AVI_RS00110	COG0159	tryptophan synthase activity
AVI_RS00115	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AVI_RS00120	COG0285	dihydrofolate synthase activity
AVI_RS00145	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AVI_RS00150	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AVI_RS00155	COG0131	Imidazoleglycerol-phosphate dehydratase
AVI_RS00160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AVI_RS00165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AVI_RS00170	COG0107	imidazoleglycerol-phosphate synthase activity
AVI_RS00175	COG0140	phosphoribosyl-ATP diphosphatase activity
AVI_RS00180	COG1072	(Pantothenic acid kinase))
AVI_RS00195	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AVI_RS00200	COG0745	RESPONSE REGULATOR receiver
AVI_RS00205	COG0642	Histidine kinase
AVI_RS00215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVI_RS00215	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVI_RS00220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVI_RS00225	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AVI_RS00230	COG2205	protein histidine kinase activity
AVI_RS00235	COG3178	'Phosphotransferase
AVI_RS00240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVI_RS00245	COG2887	Belongs to the helicase family. UvrD subfamily
AVI_RS00250	COG1074	ATP-dependent DNA helicase activity
AVI_RS00255	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AVI_RS00270	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AVI_RS00280	COG1643	Atp-dependent helicase
AVI_RS00285	COG2423	ornithine cyclodeaminase activity
AVI_RS00325	COG2814	Major facilitator Superfamily
AVI_RS00330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVI_RS00335	COG1609	Transcriptional regulator
AVI_RS00345	COG0673	inositol 2-dehydrogenase activity
AVI_RS00355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVI_RS00360	COG3962	Belongs to the TPP enzyme family
AVI_RS00375	COG3718	enzyme involved in inositol metabolism
AVI_RS00405	COG4221	oxidoreductase activity
AVI_RS00410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVI_RS00425	COG1595	DNA-templated transcription, initiation
AVI_RS00430	COG3806	Anti-sigma factor
AVI_RS00450	COG3842	ATPase activity
AVI_RS00455	COG3842	ATPase activity
AVI_RS00465	COG0395	ABC-type sugar transport system, permease component
AVI_RS00480	COG3474	cytochrome
AVI_RS00485	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AVI_RS00490	COG0077	Prephenate dehydratase
AVI_RS00490	COG1605	Chorismate mutase
AVI_RS00500	COG2816	NAD+ diphosphatase activity
AVI_RS00510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVI_RS00515	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AVI_RS00525	COG3422	double-strand break repair
AVI_RS00540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AVI_RS00545	COG0481	GTPase activity
AVI_RS00565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVI_RS00570	COG1607	acyl-coa hydrolase
AVI_RS00595	COG1393	Belongs to the ArsC family
AVI_RS00600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVI_RS00605	COG2309	aminopeptidase activity
AVI_RS00620	COG1278	Cold shock
AVI_RS00625	COG1570	exodeoxyribonuclease VII activity
AVI_RS00665	COG0667	Aldo Keto reductase
AVI_RS00680	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVI_RS00685	COG2951	lytic endotransglycosylase activity
AVI_RS00710	COG2814	Major facilitator Superfamily
AVI_RS00715	COG0779	Required for maturation of 30S ribosomal subunits
AVI_RS00720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVI_RS00720	COG0195	Participates in both transcription termination and antitermination
AVI_RS00730	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AVI_RS00735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AVI_RS00740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AVI_RS00745	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AVI_RS00755	COG1185	polyribonucleotide nucleotidyltransferase activity
AVI_RS00760	COG2813	Specifically methylates the guanine in position
AVI_RS00765	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVI_RS00775	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVI_RS00785	COG2860	membrane
AVI_RS00795	COG0477	Major facilitator Superfamily
AVI_RS00810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AVI_RS00815	COG0539	negative regulation of cytoplasmic translation
AVI_RS00835	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AVI_RS00855	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AVI_RS00860	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AVI_RS00865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AVI_RS00875	COG0072	phenylalanine-tRNA ligase activity
AVI_RS00875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVI_RS00920	COG4964	Belongs to the GSP D family
AVI_RS00960	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AVI_RS00965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVI_RS00970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVI_RS00980	COG1280	lysine exporter protein (LysE YggA)
AVI_RS00985	COG0588	phosphoglycerate mutase activity
AVI_RS00990	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AVI_RS00995	COG1132	(ABC) transporter
AVI_RS01000	COG0837	glucose binding
AVI_RS01005	COG1803	Methylglyoxal synthase
AVI_RS01010	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AVI_RS01015	COG4166	transmembrane transport
AVI_RS01020	COG4174	ABC transporter (Permease)
AVI_RS01025	COG4239	(ABC) transporter, permease
AVI_RS01030	COG4172	Belongs to the ABC transporter superfamily
AVI_RS01035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVI_RS01045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AVI_RS01070	COG1744	ABC transporter substrate-binding protein PnrA-like
AVI_RS01075	COG3845	ABC transporter
AVI_RS01080	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVI_RS01085	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVI_RS01100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AVI_RS01105	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AVI_RS01110	COG2188	Transcriptional regulator
AVI_RS01115	COG3624	Phosphonate C-P lyase system protein PhnG
AVI_RS01120	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AVI_RS01125	COG3626	phosphonate metabolism
AVI_RS01130	COG3627	carbon phosphorus lyase activity
AVI_RS01135	COG4107	phosphonate C-P lyase system protein PhnK
AVI_RS01140	COG4778	phosphonate C-P lyase system protein PhnL
AVI_RS01150	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AVI_RS01155	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AVI_RS01165	COG3639	organic phosphonate transmembrane transporter activity
AVI_RS01170	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AVI_RS01175	COG3454	Phosphonate metabolism
AVI_RS01180	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AVI_RS01200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVI_RS01205	COG2353	YceI-like domain
AVI_RS01210	COG2353	YceI-like domain
AVI_RS01220	COG0791	NLP P60 protein
AVI_RS01225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI_RS01225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI_RS01235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVI_RS01240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVI_RS01255	COG0443	Heat shock 70 kDa protein
AVI_RS01265	COG0484	heat shock protein binding
AVI_RS01270	COG2900	Belongs to the SlyX family
AVI_RS01275	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVI_RS01290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVI_RS01300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVI_RS01305	COG5001	Diguanylate cyclase
AVI_RS01310	COG3002	Belongs to the UPF0753 family
AVI_RS01340	COG0519	Catalyzes the synthesis of GMP from XMP
AVI_RS01340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AVI_RS01355	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AVI_RS01380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVI_RS01380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVI_RS01385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVI_RS01395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AVI_RS01405	COG1968	undecaprenyl-diphosphatase activity
AVI_RS01430	COG0284	orotidine-5'-phosphate decarboxylase activity
AVI_RS01440	COG3963	phosphatidate phosphatase activity
AVI_RS01450	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AVI_RS01455	COG0792	nuclease activity
AVI_RS01465	COG1175	transmembrane transport
AVI_RS01470	COG0395	ABC-type sugar transport system, permease component
AVI_RS01475	COG3842	ATPase activity
AVI_RS01485	COG0189	ligase activity
AVI_RS01490	COG0606	chelatase, subunit chli
AVI_RS01505	COG1280	lysine exporter protein (LysE YggA)
AVI_RS01515	COG0756	dUTP diphosphatase activity
AVI_RS01520	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AVI_RS01525	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AVI_RS01530	COG1877	trehalose-phosphatase activity
AVI_RS01550	COG1741	Belongs to the pirin family
AVI_RS01560	COG0583	DNA-binding transcription factor activity
AVI_RS01575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVI_RS01580	COG3920	Histidine kinase
AVI_RS01585	COG0784	Response regulator, receiver
AVI_RS01590	COG0784	Response regulator, receiver
AVI_RS01590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVI_RS01590	COG2198	Histidine kinase
AVI_RS01590	COG2205	protein histidine kinase activity
AVI_RS01595	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVI_RS01600	COG2226	methyltransferase
AVI_RS01605	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AVI_RS01610	COG0268	Binds directly to 16S ribosomal RNA
AVI_RS01615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AVI_RS01620	COG0697	spore germination
AVI_RS01625	COG2226	methyltransferase
AVI_RS01630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVI_RS01635	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AVI_RS01645	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AVI_RS01650	COG1420	regulation of RNA biosynthetic process
AVI_RS01655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVI_RS01660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVI_RS01665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AVI_RS01675	COG1137	ATPase activity
AVI_RS01680	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AVI_RS01690	COG0776	regulation of translation
AVI_RS01700	COG0116	Belongs to the methyltransferase superfamily
AVI_RS01700	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AVI_RS01705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVI_RS01710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AVI_RS01725	COG0583	DNA-binding transcription factor activity
AVI_RS01730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVI_RS01735	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AVI_RS01745	COG0346	lactoylglutathione lyase activity
AVI_RS01750	COG0180	Tryptophanyl-tRNA synthetase
AVI_RS01760	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AVI_RS01765	COG1214	PFAM Peptidase M22, glycoprotease
AVI_RS01785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVI_RS01790	COG1702	phosphate starvation-inducible protein PhoH
AVI_RS01795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AVI_RS01800	COG4535	Mg2 and Co2 transporter CorC
AVI_RS01810	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AVI_RS01815	COG1396	sequence-specific DNA binding
AVI_RS01820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AVI_RS01825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVI_RS01835	COG0071	Belongs to the small heat shock protein (HSP20) family
AVI_RS01855	COG0840	transmembrane signaling receptor activity
AVI_RS01865	COG2205	protein histidine kinase activity
AVI_RS01870	COG0594	ribonuclease P activity
AVI_RS01875	COG0706	membrane insertase activity
AVI_RS01880	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AVI_RS01885	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AVI_RS01900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVI_RS01905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVI_RS01915	COG1749	Flagellar hook protein flgE
AVI_RS01925	COG2171	N-acyltransferase activity
AVI_RS01930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVI_RS01955	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AVI_RS01960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVI_RS01970	COG0745	RESPONSE REGULATOR receiver
AVI_RS01975	COG0704	Plays a role in the regulation of phosphate uptake
AVI_RS01980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVI_RS01990	COG0573	inorganic phosphate transmembrane transporter activity
AVI_RS02000	COG5002	protein histidine kinase activity
AVI_RS02005	COG2326	polyphosphate kinase activity
AVI_RS02025	COG1125	glycine betaine transport
AVI_RS02025	COG0517	IMP dehydrogenase activity
AVI_RS02045	COG2188	Transcriptional regulator
AVI_RS02050	COG2986	histidine ammonia-lyase
AVI_RS02060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AVI_RS02065	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AVI_RS02065	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AVI_RS02075	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVI_RS02095	COG0427	acetyl-CoA hydrolase
AVI_RS02105	COG3938	Belongs to the proline racemase family
AVI_RS02110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVI_RS02115	COG0745	RESPONSE REGULATOR receiver
AVI_RS02135	COG0418	dihydroorotase activity
AVI_RS02140	COG3706	GGDEF domain
AVI_RS02145	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVI_RS02160	COG0166	Belongs to the GPI family
AVI_RS02165	COG0318	PFAM AMP-dependent synthetase and ligase
AVI_RS02180	COG1028	Short-chain dehydrogenase reductase Sdr
AVI_RS02190	COG0101	tRNA pseudouridine synthase activity
AVI_RS02195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVI_RS02200	COG0242	peptide deformylase activity
AVI_RS02205	COG2967	ApaG domain
AVI_RS02215	COG0717	Belongs to the dCTP deaminase family
AVI_RS02230	COG0640	Transcriptional regulator
AVI_RS02240	COG3293	Transposase
AVI_RS02265	COG0583	DNA-binding transcription factor activity
AVI_RS02345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVI_RS02370	COG0167	dihydroorotate dehydrogenase activity
AVI_RS02410	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVI_RS02410	COG1024	Enoyl-CoA hydratase
AVI_RS02415	COG0183	Belongs to the thiolase family
AVI_RS02420	COG1960	acyl-CoA dehydrogenase activity
AVI_RS02440	COG1785	Belongs to the alkaline phosphatase family
AVI_RS02450	COG1136	(ABC) transporter
AVI_RS02465	COG2203	Gaf domain
AVI_RS02465	COG3706	GGDEF domain
AVI_RS02465	COG4251	negative regulation of phosphorylation
AVI_RS02465	COG5001	Diguanylate cyclase
AVI_RS02470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AVI_RS02480	COG1201	RNA secondary structure unwinding
AVI_RS02500	COG1047	Peptidyl-prolyl cis-trans
AVI_RS02505	COG2198	Histidine kinase
AVI_RS02505	COG2205	protein histidine kinase activity
AVI_RS02505	COG0784	Response regulator, receiver
AVI_RS02510	COG1970	mechanosensitive ion channel activity
AVI_RS02515	COG0436	Aminotransferase
AVI_RS02520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVI_RS02540	COG1216	Glycosyl transferase, family 2
AVI_RS02565	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AVI_RS02570	COG0424	maF-like protein
AVI_RS02575	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVI_RS02585	COG5328	Belongs to the UPF0262 family
AVI_RS02590	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AVI_RS02600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AVI_RS02640	COG1309	transcriptional regulator
AVI_RS02650	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AVI_RS02655	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AVI_RS02670	COG2818	Glycosylase
AVI_RS02680	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AVI_RS02695	COG0583	DNA-binding transcription factor activity
AVI_RS02750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVI_RS02775	COG3436	PFAM IS66 Orf2 family protein
AVI_RS02780	COG4372	Transposase
AVI_RS02795	COG3436	PFAM IS66 Orf2 family protein
AVI_RS02800	COG2433	Pfam Transposase IS66
AVI_RS02810	COG1404	Belongs to the peptidase S8 family
AVI_RS02855	COG3293	Transposase
AVI_RS02900	COG1215	transferase activity, transferring glycosyl groups
AVI_RS02910	COG0488	(ABC) transporter
AVI_RS02935	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVI_RS02940	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVI_RS02945	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVI_RS02950	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVI_RS02955	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AVI_RS02960	COG4786	Flagellar basal body rod
AVI_RS02965	COG1157	protein secretion by the type III secretion system
AVI_RS02975	COG1815	bacterial-type flagellum-dependent cell motility
AVI_RS02980	COG1558	bacterial-type flagellum-dependent cell motility
AVI_RS02985	COG1677	Flagellar hook-basal body complex protein FliE
AVI_RS02990	COG4786	Flagellar basal body rod
AVI_RS02995	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AVI_RS03000	COG1706	bacterial-type flagellum-dependent cell motility
AVI_RS03010	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AVI_RS03020	COG1338	Plays a role in the flagellum-specific transport system
AVI_RS03025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVI_RS03030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVI_RS03035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVI_RS03040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVI_RS03045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVI_RS03055	COG1360	Flagellar Motor Protein
AVI_RS03085	COG1749	Flagellar hook protein flgE
AVI_RS03105	COG5443	negative regulation of bacterial-type flagellum assembly
AVI_RS03110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AVI_RS03115	COG4794	Type iii secretion
AVI_RS03120	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVI_RS03155	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AVI_RS03160	COG1609	Transcriptional regulator
AVI_RS03165	COG1653	transport
AVI_RS03170	COG1175	transmembrane transport
AVI_RS03175	COG0395	ABC-type sugar transport system, permease component
AVI_RS03180	COG0366	Alpha amylase catalytic
AVI_RS03185	COG3842	ATPase activity
AVI_RS03200	COG3493	citrate carrier protein
AVI_RS03210	COG0129	dihydroxy-acid dehydratase activity
AVI_RS03215	COG0363	glucosamine-6-phosphate deaminase activity
AVI_RS03220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AVI_RS03225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVI_RS03235	COG2081	HI0933 family
AVI_RS03245	COG0840	transmembrane signaling receptor activity
AVI_RS03245	COG2972	Histidine kinase
AVI_RS03255	COG5265	(ABC) transporter
AVI_RS03270	COG2224	Isocitrate lyase
AVI_RS03285	COG3842	ATPase activity
AVI_RS03290	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVI_RS03295	COG1177	transmembrane transport
AVI_RS03305	COG2205	protein histidine kinase activity
AVI_RS03355	COG1959	2 iron, 2 sulfur cluster binding
AVI_RS03360	COG3265	gluconokinase activity
AVI_RS03365	COG2134	cdp-diacylglycerol pyrophosphatase
AVI_RS03370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVI_RS03375	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AVI_RS03395	COG0579	oxidoreductase
AVI_RS03560	COG0582	viral genome integration into host DNA
AVI_RS03570	COG0248	Ppx GppA phosphatase
AVI_RS03575	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AVI_RS03585	COG5001	Diguanylate cyclase
AVI_RS03585	COG3300	MHYT domain
AVI_RS03590	COG5002	protein histidine kinase activity
AVI_RS03590	COG2198	Histidine kinase
AVI_RS03590	COG0784	Response regulator, receiver
AVI_RS03595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AVI_RS03605	COG1663	tetraacyldisaccharide 4'-kinase activity
AVI_RS03615	COG1519	Transferase
AVI_RS03630	COG0312	modulator of DNA gyrase
AVI_RS03635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVI_RS03635	COG0475	glutathione-regulated potassium exporter activity
AVI_RS03645	COG0742	ribosomal rna small subunit methyltransferase
AVI_RS03650	COG1187	pseudouridine synthase activity
AVI_RS03655	COG0590	tRNA wobble adenosine to inosine editing
AVI_RS03665	COG0477	Major facilitator Superfamily
AVI_RS03675	COG3386	PFAM SMP-30 Gluconolaconase
AVI_RS03680	COG2771	luxR family
AVI_RS03685	COG1116	anion transmembrane transporter activity
AVI_RS03685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVI_RS03700	COG0598	Magnesium transport protein CorA
AVI_RS03705	COG3158	transport of potassium into the cell
AVI_RS03715	COG0356	it plays a direct role in the translocation of protons across the membrane
AVI_RS03725	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVI_RS03730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVI_RS03735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AVI_RS03750	COG0521	Mo-molybdopterin cofactor biosynthetic process
AVI_RS03755	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AVI_RS03765	COG0142	geranyltranstransferase activity
AVI_RS03795	COG0752	glycyl-tRNA synthetase alpha subunit
AVI_RS03805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVI_RS03810	COG0751	glycine-tRNA ligase activity
AVI_RS03815	COG1683	Conserved Protein
AVI_RS03820	COG0840	transmembrane signaling receptor activity
AVI_RS03820	COG0840	transmembrane signaling receptor activity
AVI_RS03830	COG0151	Belongs to the GarS family
AVI_RS03840	COG2183	response to ionizing radiation
AVI_RS03845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVI_RS03875	COG0725	ABC transporter, periplasmic molybdate-binding protein
AVI_RS03880	COG4149	molybdate abc transporter
AVI_RS03885	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AVI_RS03900	COG0009	L-threonylcarbamoyladenylate synthase
AVI_RS03910	COG0840	transmembrane signaling receptor activity
AVI_RS03915	COG4638	Rieske (2fe-2S)
AVI_RS03940	COG1960	acyl-CoA dehydrogenase activity
AVI_RS03945	COG1024	Enoyl-CoA hydratase
AVI_RS03960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVI_RS03965	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AVI_RS03975	COG0840	transmembrane signaling receptor activity
AVI_RS03985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AVI_RS03990	COG1722	exodeoxyribonuclease VII activity
AVI_RS03995	COG0123	including yeast histone deacetylase and acetoin utilization protein
AVI_RS04010	COG1268	BioY protein
AVI_RS04015	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AVI_RS04020	COG1122	ATPase activity
AVI_RS04030	COG3214	Protein conserved in bacteria
AVI_RS04050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVI_RS04050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVI_RS04055	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AVI_RS04060	COG5001	Diguanylate cyclase
AVI_RS04060	COG3300	MHYT domain
AVI_RS04075	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVI_RS04080	COG0484	heat shock protein binding
AVI_RS04090	COG0259	pyridoxamine-phosphate oxidase activity
AVI_RS04100	COG2814	Major facilitator Superfamily
AVI_RS04105	COG0789	Transcriptional regulator
AVI_RS04110	COG1686	Belongs to the peptidase S11 family
AVI_RS04125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVI_RS04135	COG0312	modulator of DNA gyrase
AVI_RS04150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVI_RS04155	COG0109	protoheme IX farnesyltransferase activity
AVI_RS04165	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AVI_RS04180	COG3346	SURF1 family
AVI_RS04190	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AVI_RS04205	COG1280	lysine exporter protein (LysE YggA)
AVI_RS04210	COG0436	Aminotransferase
AVI_RS04220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AVI_RS04225	COG0328	RNA-DNA hybrid ribonuclease activity
AVI_RS04235	COG0803	Belongs to the bacterial solute-binding protein 9 family
AVI_RS04250	COG0678	peroxiredoxin activity
AVI_RS04250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVI_RS04260	COG1678	Uncharacterized ACR, COG1678
AVI_RS04270	COG0640	Transcriptional regulator
AVI_RS04275	COG5001	Diguanylate cyclase
AVI_RS04280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVI_RS04285	COG0612	Peptidase, M16
AVI_RS04300	COG1597	lipid kinase activity
AVI_RS04305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVI_RS04320	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AVI_RS04350	COG1194	a g-specific adenine glycosylase
AVI_RS04365	COG1196	nuclear chromosome segregation
AVI_RS04380	COG2814	Major facilitator Superfamily
AVI_RS04395	COG0574	Belongs to the PEP-utilizing enzyme family
AVI_RS04395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AVI_RS04430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI_RS04450	COG0840	transmembrane signaling receptor activity
AVI_RS04455	COG0175	sulfate reduction
AVI_RS04460	COG0175	sulfate reduction
AVI_RS04465	COG2895	sulfate adenylyltransferase (ATP) activity
AVI_RS04475	COG1609	Transcriptional regulator
AVI_RS04485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVI_RS04495	COG0693	protein deglycase activity
AVI_RS04515	COG0038	chloride channel
AVI_RS04520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVI_RS04545	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AVI_RS04555	COG1012	belongs to the aldehyde dehydrogenase family
AVI_RS04560	COG0625	glutathione transferase activity
AVI_RS04565	COG3119	arylsulfatase activity
AVI_RS04570	COG1309	transcriptional regulator
AVI_RS04575	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AVI_RS04590	COG3293	Transposase
AVI_RS04600	COG0840	transmembrane signaling receptor activity
AVI_RS04625	COG1349	DNA-binding transcription factor activity
AVI_RS04675	COG0477	Major facilitator Superfamily
AVI_RS04685	COG0778	Nitroreductase
AVI_RS04710	COG1388	LysM domain
AVI_RS04710	COG1376	ErfK ybiS ycfS ynhG family protein
AVI_RS04715	COG1376	ErfK ybiS ycfS ynhG family protein
AVI_RS04720	COG1846	Transcriptional regulator
AVI_RS04725	COG1764	response to oxidative stress
AVI_RS04740	COG4191	Histidine kinase
AVI_RS04740	COG0784	Response regulator, receiver
AVI_RS04750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVI_RS04755	COG0840	transmembrane signaling receptor activity
AVI_RS04760	COG0840	transmembrane signaling receptor activity
AVI_RS04770	COG0433	COG0433 Predicted ATPase
AVI_RS04790	COG0840	transmembrane signaling receptor activity
AVI_RS04795	COG1968	undecaprenyl-diphosphatase activity
AVI_RS04805	COG4214	carbohydrate transport
AVI_RS04810	COG4213	ABC transporter substrate-binding protein
AVI_RS04815	COG1940	carbohydrate kinase activity
AVI_RS04815	COG1846	Transcriptional regulator
AVI_RS04835	COG1120	ATPase activity
AVI_RS04840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVI_RS04855	COG2226	methyltransferase
AVI_RS04865	COG2814	Major facilitator Superfamily
AVI_RS04870	COG3320	Male sterility
AVI_RS04870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVI_RS04905	COG2010	Cytochrome c
AVI_RS04920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVI_RS04935	COG1733	regulation of RNA biosynthetic process
AVI_RS04945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AVI_RS04960	COG5002	protein histidine kinase activity
AVI_RS04960	COG5001	Diguanylate cyclase
AVI_RS04960	COG3447	MASE1 domain protein
AVI_RS04965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVI_RS05015	COG2514	catechol 2,3-dioxygenase activity
AVI_RS05030	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AVI_RS05035	COG1272	protein, Hemolysin III
AVI_RS05040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVI_RS05045	COG1247	-acetyltransferase
AVI_RS05060	COG4957	zinc ion binding
AVI_RS05065	COG1320	monovalent cation:proton antiporter activity
AVI_RS05070	COG2212	antiporter activity
AVI_RS05075	COG1863	multisubunit Na H antiporter MnhE subunit
AVI_RS05080	COG0651	ATP synthesis coupled electron transport
AVI_RS05085	COG1006	Multisubunit Na H antiporter MnhC subunit
AVI_RS05090	COG2111	Na H antiporter
AVI_RS05095	COG2111	Na H antiporter
AVI_RS05095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AVI_RS05100	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI_RS05125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI_RS05130	COG1136	(ABC) transporter
AVI_RS05130	COG0577	efflux transmembrane transporter activity
AVI_RS05150	COG2166	iron-sulfur cluster assembly
AVI_RS05160	COG2205	protein histidine kinase activity
AVI_RS05175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVI_RS05230	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AVI_RS05235	COG2983	Belongs to the UPF0260 family
AVI_RS05250	COG0789	Transcriptional regulator
AVI_RS05270	COG4695	Portal protein
AVI_RS05370	COG4520	surface antigen
AVI_RS05375	COG4235	cytochrome complex assembly
AVI_RS05380	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AVI_RS05385	COG1138	Cytochrome C-type biogenesis protein
AVI_RS05390	COG3088	subunit of a heme lyase
AVI_RS05395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVI_RS05400	COG0745	RESPONSE REGULATOR receiver
AVI_RS05405	COG2205	protein histidine kinase activity
AVI_RS05410	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AVI_RS05415	COG2202	Pas domain
AVI_RS05415	COG2205	protein histidine kinase activity
AVI_RS05420	COG0308	aminopeptidase N
AVI_RS05425	COG3290	protein histidine kinase activity
AVI_RS05425	COG0840	transmembrane signaling receptor activity
AVI_RS05450	COG0443	Heat shock 70 kDa protein
AVI_RS05465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI_RS05480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVI_RS05485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVI_RS05500	COG2239	Acts as a magnesium transporter
AVI_RS05505	COG2814	Major facilitator Superfamily
AVI_RS05515	COG4172	Belongs to the ABC transporter superfamily
AVI_RS05520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVI_RS05525	COG0601	transmembrane transport
AVI_RS05530	COG4166	transmembrane transport
AVI_RS05535	COG0174	glutamine synthetase
AVI_RS05550	COG1695	Transcriptional regulator
AVI_RS05555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AVI_RS05560	COG0463	Glycosyl transferase, family 2
AVI_RS05570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVI_RS05580	COG0625	glutathione transferase activity
AVI_RS05595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVI_RS05635	COG0741	lytic transglycosylase activity
AVI_RS05640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVI_RS05645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AVI_RS05655	COG2169	Transcriptional regulator
AVI_RS05655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVI_RS05660	COG0840	transmembrane signaling receptor activity
AVI_RS05670	COG1758	RNA polymerase activity
AVI_RS05680	COG0681	Belongs to the peptidase S26 family
AVI_RS05685	COG0571	ribonuclease III activity
AVI_RS05690	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AVI_RS05695	COG3180	Ammonia monooxygenase
AVI_RS05700	COG1381	Involved in DNA repair and RecF pathway recombination
AVI_RS05715	COG1418	mRNA catabolic process
AVI_RS05730	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AVI_RS05735	COG0354	folic acid binding
AVI_RS05755	COG1051	belongs to the nudix hydrolase family
AVI_RS05765	COG1183	phosphatidylcholine synthase activity
AVI_RS05770	COG0688	phosphatidylethanolamine metabolic process
AVI_RS05775	COG5265	(ABC) transporter
AVI_RS05780	COG1652	LysM domain
AVI_RS05780	COG2823	Periplasmic or secreted lipoprotein
AVI_RS05795	COG2962	Rard protein
AVI_RS05800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVI_RS05840	COG0215	cysteine-tRNA ligase activity
AVI_RS05845	COG5434	Belongs to the glycosyl hydrolase 28 family
AVI_RS05850	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AVI_RS05855	COG1088	dTDP-glucose 4,6-dehydratase activity
AVI_RS05860	COG1091	dTDP-4-dehydrorhamnose reductase activity
AVI_RS05865	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AVI_RS05880	COG4221	oxidoreductase activity
AVI_RS05885	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AVI_RS05890	COG1286	toxin biosynthetic process
AVI_RS05895	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AVI_RS05900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVI_RS05915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVI_RS05920	COG1917	Cupin 2, conserved barrel domain protein
AVI_RS05920	COG2207	Transcriptional regulator
AVI_RS05925	COG0765	amino acid transport
AVI_RS05930	COG0765	amino acid transport
AVI_RS05940	COG0305	Participates in initiation and elongation during chromosome replication
AVI_RS05945	COG0359	binds to the 23S rRNA
AVI_RS05955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AVI_RS05960	COG0360	Binds together with S18 to 16S ribosomal RNA
AVI_RS05980	COG0667	Aldo Keto reductase
AVI_RS05985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVI_RS05995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVI_RS06000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVI_RS06005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVI_RS06010	COG1561	YicC-like family, N-terminal region
AVI_RS06015	COG0194	GDP metabolic process
AVI_RS06020	COG0500	methyltransferase
AVI_RS06025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVI_RS06030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AVI_RS06040	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AVI_RS06055	COG0671	phosphoesterase, PA-phosphatase related
AVI_RS06060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVI_RS06070	COG0840	transmembrane signaling receptor activity
AVI_RS06075	COG0488	(ABC) transporter
AVI_RS06085	COG0105	UTP biosynthetic process
AVI_RS06090	COG0314	molybdopterin synthase activity
AVI_RS06100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AVI_RS06105	COG0322	excinuclease ABC activity
AVI_RS06110	COG1028	Short-chain dehydrogenase reductase Sdr
AVI_RS06120	COG0625	glutathione transferase activity
AVI_RS06125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AVI_RS06130	COG0243	molybdopterin cofactor binding
AVI_RS06140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVI_RS06140	COG3453	Protein conserved in bacteria
AVI_RS06145	COG0640	Transcriptional regulator
AVI_RS06160	COG0730	response to heat
AVI_RS06165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVI_RS06170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AVI_RS06175	COG0628	permease
AVI_RS06185	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AVI_RS06190	COG0248	Ppx GppA phosphatase
AVI_RS06195	COG1321	iron dependent repressor
AVI_RS06200	COG1914	H( )-stimulated, divalent metal cation uptake system
AVI_RS06220	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AVI_RS06235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVI_RS06250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AVI_RS06255	COG5001	Diguanylate cyclase
AVI_RS06255	COG3300	MHYT domain
AVI_RS06265	COG2203	Gaf domain
AVI_RS06265	COG2200	EAL domain
AVI_RS06265	COG2199	diguanylate cyclase activity
AVI_RS06270	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AVI_RS06280	COG0113	porphobilinogen synthase activity
AVI_RS06300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVI_RS06305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AVI_RS06310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVI_RS06310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVI_RS06325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVI_RS06330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVI_RS06335	COG2814	Major facilitator Superfamily
AVI_RS06340	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AVI_RS06360	COG0416	fatty acid biosynthetic process
AVI_RS06365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVI_RS06370	COG0776	regulation of translation
AVI_RS06395	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AVI_RS06415	COG0464	growth
AVI_RS06485	COG0438	transferase activity, transferring glycosyl groups
AVI_RS06525	COG1612	heme a metabolic process
AVI_RS06530	COG3384	dioxygenase
AVI_RS06540	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AVI_RS06545	COG0010	Belongs to the arginase family
AVI_RS06560	COG2329	Antibiotic biosynthesis monooxygenase
AVI_RS06565	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AVI_RS06570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AVI_RS06575	COG1832	CoA-binding protein
AVI_RS06585	COG1832	CoA-binding protein
AVI_RS06595	COG1408	metallophosphoesterase
AVI_RS06605	COG2124	cytochrome p450
AVI_RS06615	COG0740	serine-type endopeptidase activity
AVI_RS06620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVI_RS06625	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVI_RS06650	COG1024	Enoyl-CoA hydratase
AVI_RS06685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVI_RS06690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVI_RS06695	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVI_RS06700	COG0649	NAD binding
AVI_RS06710	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AVI_RS06715	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AVI_RS06720	COG0052	Belongs to the universal ribosomal protein uS2 family
AVI_RS06730	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AVI_RS06735	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVI_RS06745	COG0713	ATP synthesis coupled electron transport
AVI_RS06760	COG1007	ATP synthesis coupled electron transport
AVI_RS06775	COG0346	lactoylglutathione lyase activity
AVI_RS06780	COG0251	oxidation-reduction process
AVI_RS06795	COG0442	prolyl-tRNA aminoacylation
AVI_RS06805	COG1136	(ABC) transporter
AVI_RS06820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVI_RS06835	COG0784	Response regulator, receiver
AVI_RS06845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVI_RS06850	COG0477	Major facilitator Superfamily
AVI_RS06860	COG0557	exoribonuclease II activity
AVI_RS06865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AVI_RS06875	COG0758	DNA mediated transformation
AVI_RS06880	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVI_RS06890	COG0540	Belongs to the ATCase OTCase family
AVI_RS06895	COG1960	acyl-CoA dehydrogenase activity
AVI_RS06915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AVI_RS06920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AVI_RS06925	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVI_RS06930	COG0154	amidase activity
AVI_RS06945	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AVI_RS06950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVI_RS06950	COG3952	Lipid A Biosynthesis
AVI_RS06955	COG0463	Glycosyl transferase, family 2
AVI_RS06965	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVI_RS06985	COG4765	Protein conserved in bacteria
AVI_RS06990	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AVI_RS07000	COG0511	ligase activity, forming carbon-carbon bonds
AVI_RS07005	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVI_RS07010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVI_RS07015	COG0436	Aminotransferase
AVI_RS07025	COG1530	ribonuclease E activity
AVI_RS07025	COG1530	ribonuclease E activity
AVI_RS07030	COG0860	N-Acetylmuramoyl-L-alanine amidase
AVI_RS07035	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AVI_RS07045	COG0284	orotidine-5'-phosphate decarboxylase activity
AVI_RS07055	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AVI_RS07070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVI_RS07085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AVI_RS07110	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVI_RS07120	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVI_RS07125	COG0081	regulation of translation
AVI_RS07130	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVI_RS07135	COG0222	ribosome binding
AVI_RS07140	COG0085	RNA polymerase activity
AVI_RS07145	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AVI_RS07160	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVI_RS07165	COG0049	tRNA binding
AVI_RS07170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVI_RS07175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AVI_RS07180	COG0051	transcription antitermination factor activity, RNA binding
AVI_RS07185	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AVI_RS07190	COG0088	Forms part of the polypeptide exit tunnel
AVI_RS07195	COG0089	rRNA binding
AVI_RS07200	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AVI_RS07205	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVI_RS07210	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AVI_RS07215	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVI_RS07220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AVI_RS07225	COG0255	Belongs to the universal ribosomal protein uL29 family
AVI_RS07230	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVI_RS07235	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AVI_RS07240	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AVI_RS07245	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AVI_RS07250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AVI_RS07255	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AVI_RS07260	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AVI_RS07265	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVI_RS07270	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AVI_RS07275	COG1841	ribosomal large subunit assembly
AVI_RS07280	COG0200	Binds to the 23S rRNA
AVI_RS07285	COG0201	protein transport
AVI_RS07290	COG0563	adenylate kinase activity
AVI_RS07295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AVI_RS07300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AVI_RS07305	COG0202	RNA polymerase activity
AVI_RS07310	COG0203	ribosomal protein L17
AVI_RS07330	COG2897	thiosulfate sulfurtransferase activity
AVI_RS07340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVI_RS07345	COG0415	Belongs to the DNA photolyase family
AVI_RS07355	COG0739	heme binding
AVI_RS07360	COG2833	Protein of unknown function (DUF455)
AVI_RS07365	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AVI_RS07390	COG0281	malic enzyme
AVI_RS07390	COG0280	phosphate acetyltransferase
AVI_RS07400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVI_RS07405	COG1127	ABC transporter
AVI_RS07415	COG3218	ABC-type transport auxiliary lipoprotein component
AVI_RS07415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVI_RS07420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVI_RS07440	COG0047	phosphoribosylformylglycinamidine synthase activity
AVI_RS07445	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVI_RS07450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AVI_RS07465	COG3706	GGDEF domain
AVI_RS07475	COG0538	isocitrate dehydrogenase activity
AVI_RS07480	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AVI_RS07485	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AVI_RS07495	COG1253	flavin adenine dinucleotide binding
AVI_RS07505	COG0657	acetylesterase activity
AVI_RS07505	COG2755	lipolytic protein G-D-S-L family
AVI_RS07510	COG2195	Cleaves the N-terminal amino acid of tripeptides
AVI_RS07525	COG0861	Integral membrane protein TerC family
AVI_RS07530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AVI_RS07535	COG2066	Belongs to the glutaminase family
AVI_RS07545	COG0037	tRNA processing
AVI_RS07550	COG0483	inositol monophosphate 1-phosphatase activity
AVI_RS07555	COG0483	inositol monophosphate 1-phosphatase activity
AVI_RS07560	COG2814	Major facilitator Superfamily
AVI_RS07565	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AVI_RS07580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVI_RS07585	COG0484	heat shock protein binding
AVI_RS07595	COG0321	lipoyl(octanoyl) transferase activity
AVI_RS07740	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AVI_RS07745	COG1091	dTDP-4-dehydrorhamnose reductase activity
AVI_RS07750	COG1088	dTDP-glucose 4,6-dehydratase activity
AVI_RS07755	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AVI_RS07890	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AVI_RS07895	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AVI_RS07925	COG0242	peptide deformylase activity
AVI_RS07935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVI_RS07940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVI_RS07945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVI_RS07950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVI_RS07955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVI_RS07980	COG0823	Involved in the tonB-independent uptake of proteins
AVI_RS07985	COG0778	Nitroreductase
AVI_RS08000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AVI_RS08005	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AVI_RS08025	COG2205	protein histidine kinase activity
AVI_RS08025	COG2202	Pas domain
AVI_RS08035	COG1573	uracil-dna glycosylase
AVI_RS08040	COG1522	sequence-specific DNA binding
AVI_RS08045	COG2084	Dehydrogenase
AVI_RS08050	COG2267	carboxylic ester hydrolase activity
AVI_RS08060	COG5425	PFAM Usg family protein
AVI_RS08085	COG1763	Mo-molybdopterin cofactor biosynthetic process
AVI_RS08090	COG0746	molybdenum cofactor guanylyltransferase activity
AVI_RS08100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVI_RS08110	COG3706	GGDEF domain
AVI_RS08120	COG0114	fumarate hydratase activity
AVI_RS08125	COG2989	Protein conserved in bacteria
AVI_RS08130	COG0546	phosphoglycolate phosphatase activity
AVI_RS08135	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVI_RS08150	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AVI_RS08185	COG5001	Diguanylate cyclase
AVI_RS08185	COG4251	negative regulation of phosphorylation
AVI_RS08185	COG2203	Gaf domain
AVI_RS08185	COG3706	GGDEF domain
AVI_RS08190	COG0556	nucleotide-excision repair
AVI_RS08210	COG3161	chorismate lyase activity
AVI_RS08220	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AVI_RS08225	COG0148	phosphopyruvate hydratase activity
AVI_RS08235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AVI_RS08240	COG0022	dehydrogenase e1 component
AVI_RS08240	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVI_RS08245	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVI_RS08265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVI_RS08275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AVI_RS08280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVI_RS08290	COG0477	Major facilitator Superfamily
AVI_RS08295	COG2867	negative regulation of translational initiation
AVI_RS08305	COG1058	Belongs to the CinA family
AVI_RS08305	COG1546	Belongs to the CinA family
AVI_RS08310	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AVI_RS08310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AVI_RS08320	COG3852	Histidine kinase
AVI_RS08325	COG2204	response regulator
AVI_RS08330	COG5000	phosphorelay sensor kinase activity
AVI_RS08335	COG2204	response regulator
AVI_RS08345	COG1923	regulation of RNA biosynthetic process
AVI_RS08350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVI_RS08360	COG3956	TIGRFAM MazG family protein
AVI_RS08370	COG1648	precorrin-2 dehydrogenase activity
AVI_RS08370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVI_RS08395	COG1028	Short-chain dehydrogenase reductase Sdr
AVI_RS08405	COG1686	Belongs to the peptidase S11 family
AVI_RS08410	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AVI_RS08420	COG0730	response to heat
AVI_RS08425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVI_RS08430	COG0084	hydrolase, TatD family'
AVI_RS08435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AVI_RS08435	COG0321	lipoyl(octanoyl) transferase activity
AVI_RS08450	COG0785	Cytochrome C biogenesis protein
AVI_RS08455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVI_RS08460	COG1183	phosphatidylcholine synthase activity
AVI_RS08465	COG3845	ABC transporter
AVI_RS08470	COG4603	Belongs to the binding-protein-dependent transport system permease family
AVI_RS08475	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVI_RS08485	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVI_RS08490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVI_RS08510	COG1177	transmembrane transport
AVI_RS08515	COG4149	molybdate abc transporter
AVI_RS08520	COG3842	ATPase activity
AVI_RS08535	COG0523	cobalamin synthesis protein
AVI_RS08545	COG1121	(ABC) transporter
AVI_RS08550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AVI_RS08555	COG0735	belongs to the Fur family
AVI_RS08575	COG1686	Belongs to the peptidase S11 family
AVI_RS08610	COG1752	Esterase of the alpha-beta hydrolase superfamily
AVI_RS08615	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AVI_RS08620	COG0302	gtp cyclohydrolase
AVI_RS08630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AVI_RS08635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AVI_RS08650	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AVI_RS08655	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AVI_RS08700	COG0187	DNA topoisomerase II activity
AVI_RS08715	COG0149	triose-phosphate isomerase activity
AVI_RS08725	COG0504	CTP synthase activity
AVI_RS08750	COG0633	Ferredoxin
AVI_RS08780	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVI_RS08780	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVI_RS08785	COG0509	glycine decarboxylation via glycine cleavage system
AVI_RS08790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVI_RS08810	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AVI_RS08815	COG0564	pseudouridine synthase activity
AVI_RS08820	COG0546	phosphoglycolate phosphatase activity
AVI_RS08835	COG0477	Major facilitator Superfamily
AVI_RS08855	COG2003	Belongs to the UPF0758 family
AVI_RS08860	COG0024	Methionine aminopeptidase
AVI_RS08865	COG0583	DNA-binding transcription factor activity
AVI_RS08870	COG2855	membrane
AVI_RS08875	COG1489	DNA binding
AVI_RS08880	COG3243	poly(R)-hydroxyalkanoic acid synthase
AVI_RS08890	COG0436	Aminotransferase
AVI_RS08900	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AVI_RS08925	COG0346	lactoylglutathione lyase activity
AVI_RS08930	COG1278	Cold shock
AVI_RS08955	COG0582	viral genome integration into host DNA
AVI_RS08975	COG0587	DNA-directed DNA polymerase activity
AVI_RS09000	COG1598	PFAM Uncharacterised protein family UPF0150
AVI_RS09260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVI_RS09270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVI_RS09280	COG0697	spore germination
AVI_RS09305	COG0174	glutamine synthetase
AVI_RS09310	COG0347	Belongs to the P(II) protein family
AVI_RS09315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AVI_RS09315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVI_RS09330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AVI_RS09335	COG0629	single-stranded DNA binding
AVI_RS09345	COG2095	MarC family integral membrane protein
AVI_RS09350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AVI_RS09380	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AVI_RS09400	COG1175	transmembrane transport
AVI_RS09405	COG0395	ABC-type sugar transport system, permease component
AVI_RS09410	COG3842	ATPase activity
AVI_RS09430	COG0667	Aldo Keto reductase
AVI_RS09435	COG3507	Belongs to the glycosyl hydrolase 43 family
AVI_RS09450	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AVI_RS09455	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AVI_RS09460	COG0129	dihydroxy-acid dehydratase activity
AVI_RS09465	COG0346	lactoylglutathione lyase activity
AVI_RS09480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVI_RS09505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVI_RS09530	COG0513	Belongs to the DEAD box helicase family
AVI_RS09535	COG1280	lysine exporter protein (LysE YggA)
AVI_RS09540	COG2945	thiolester hydrolase activity
AVI_RS09550	COG0719	Fe-S assembly protein
AVI_RS09560	COG0396	ATPase activity
AVI_RS09565	COG0719	Fe-S assembly protein
AVI_RS09575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVI_RS09580	COG2151	metal-sulfur cluster biosynthetic enzyme
AVI_RS09590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AVI_RS09605	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AVI_RS09610	COG0343	queuine tRNA-ribosyltransferase activity
AVI_RS09620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AVI_RS09630	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AVI_RS09635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVI_RS09640	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AVI_RS09645	COG2080	2 iron, 2 sulfur cluster binding
AVI_RS09680	COG3106	COG3106 Predicted ATPase
AVI_RS09685	COG3768	UPF0283 membrane protein
AVI_RS09700	COG0436	Aminotransferase
AVI_RS09710	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AVI_RS09715	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVI_RS09745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVI_RS09750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVI_RS09765	COG0252	asparaginase activity
AVI_RS09775	COG0737	Belongs to the 5'-nucleotidase family
AVI_RS09785	COG0463	Glycosyl transferase, family 2
AVI_RS09790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AVI_RS09810	COG1116	anion transmembrane transporter activity
AVI_RS09815	COG3665	Urea carboxylase-associated protein
AVI_RS09825	COG4770	biotin carboxylase activity
AVI_RS09845	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AVI_RS09850	COG2153	protein acetylation
AVI_RS09855	COG1671	Belongs to the UPF0178 family
AVI_RS09865	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AVI_RS09870	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVI_RS09880	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVI_RS09885	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVI_RS09890	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVI_RS09895	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVI_RS09900	COG0750	zinc metalloprotease
AVI_RS09910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVI_RS09915	COG0233	cytoplasmic translational termination
AVI_RS09920	COG0528	UMP kinase activity
AVI_RS09925	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AVI_RS09930	COG0052	Belongs to the universal ribosomal protein uS2 family
AVI_RS09955	COG0537	adenosine 5'-monophosphoramidase activity
AVI_RS09975	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVI_RS10000	COG2267	carboxylic ester hydrolase activity
AVI_RS10020	COG0626	cystathionine gamma-synthase activity
AVI_RS10025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVI_RS10030	COG4597	amino acid ABC transporter
AVI_RS10035	COG0765	amino acid transport
AVI_RS10040	COG1126	abc transporter atp-binding protein
AVI_RS10045	COG0154	amidase activity
AVI_RS10050	COG0154	amidase activity
AVI_RS10055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AVI_RS10060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AVI_RS10070	COG2313	pseudouridylate synthase activity
AVI_RS10075	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AVI_RS10080	COG2333	competence protein COMEC
AVI_RS10080	COG0658	competence protein
AVI_RS10085	COG0372	Belongs to the citrate synthase family
AVI_RS10095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVI_RS10100	COG0134	indole-3-glycerol-phosphate synthase activity
AVI_RS10105	COG0315	cyclic pyranopterin monophosphate synthase activity
AVI_RS10110	COG0303	'Molybdopterin
AVI_RS10115	COG0671	phosphoesterase, PA-phosphatase related
AVI_RS10120	COG1492	cobalamin metabolic process
AVI_RS10130	COG4176	ABC-type proline glycine betaine transport system permease component
AVI_RS10135	COG4175	Glycine betaine
AVI_RS10135	COG0517	IMP dehydrogenase activity
AVI_RS10155	COG3698	Phosphodiester glycosidase
AVI_RS10175	COG0583	DNA-binding transcription factor activity
AVI_RS10205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVI_RS10220	COG0681	Belongs to the peptidase S26 family
AVI_RS10225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVI_RS10230	COG0840	transmembrane signaling receptor activity
AVI_RS10240	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AVI_RS10250	COG1546	Belongs to the CinA family
AVI_RS10250	COG1058	Belongs to the CinA family
AVI_RS10255	COG2972	Histidine kinase
AVI_RS10255	COG0840	transmembrane signaling receptor activity
AVI_RS10265	COG0835	chemotaxis
AVI_RS10275	COG1760	l-serine dehydratase
AVI_RS10300	COG2239	Acts as a magnesium transporter
AVI_RS10325	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AVI_RS10330	COG2099	Precorrin-6x reductase
AVI_RS10350	COG2875	Belongs to the precorrin methyltransferase family
AVI_RS10430	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AVI_RS10455	COG1862	Preprotein translocase
AVI_RS10470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AVI_RS10475	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AVI_RS10480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVI_RS10485	COG0805	protein transport
AVI_RS10495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVI_RS10500	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVI_RS10505	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AVI_RS10510	COG1472	Belongs to the glycosyl hydrolase 3 family
AVI_RS10520	COG0018	arginyl-trna synthetase
AVI_RS10525	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AVI_RS10530	COG0316	Belongs to the HesB IscA family
AVI_RS10555	COG0525	valine-tRNA ligase activity
AVI_RS10570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AVI_RS10600	COG0584	glycerophosphoryl diester phosphodiesterase
AVI_RS10605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVI_RS10635	COG0583	DNA-binding transcription factor activity
AVI_RS10645	COG3842	ATPase activity
AVI_RS10650	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVI_RS10655	COG1177	transmembrane transport
AVI_RS10675	COG0251	oxidation-reduction process
AVI_RS10690	COG3547	Transposase (IS116 IS110 IS902 family)
AVI_RS10715	COG0842	Transport permease protein
AVI_RS10720	COG1131	(ABC) transporter
AVI_RS10725	COG0745	RESPONSE REGULATOR receiver
AVI_RS10740	COG2226	methyltransferase
AVI_RS10745	COG3264	Mechanosensitive ion channel
AVI_RS10745	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AVI_RS10760	COG4558	Periplasmic binding protein
AVI_RS10765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVI_RS10770	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AVI_RS10805	COG0270	DNA (cytosine-5-)-methyltransferase activity
AVI_RS10850	COG2801	Transposase and inactivated derivatives
AVI_RS10945	COG0384	phenazine biosynthesis protein PhzF
AVI_RS10970	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AVI_RS10980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVI_RS11000	COG1522	sequence-specific DNA binding
AVI_RS11005	COG1794	racemase activity, acting on amino acids and derivatives
AVI_RS11010	COG1309	transcriptional regulator
AVI_RS11015	COG2814	Major facilitator Superfamily
AVI_RS11025	COG1733	regulation of RNA biosynthetic process
AVI_RS11035	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AVI_RS11040	COG0789	Transcriptional regulator
AVI_RS11045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVI_RS11055	COG0656	L-ascorbic acid biosynthetic process
AVI_RS11070	COG0028	Belongs to the TPP enzyme family
AVI_RS11090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AVI_RS11095	COG0560	Phosphoserine phosphatase
AVI_RS11095	COG3830	Belongs to the UPF0237 family
AVI_RS11110	COG0330	HflC and HflK could
AVI_RS11125	COG2259	Doxx family
AVI_RS11130	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AVI_RS11165	COG0277	FAD linked oxidase domain protein
AVI_RS11170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVI_RS11175	COG0581	inorganic phosphate transmembrane transporter activity
AVI_RS11180	COG0573	inorganic phosphate transmembrane transporter activity
AVI_RS11185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AVI_RS11220	COG4993	Dehydrogenase
AVI_RS11225	COG1335	isochorismatase
AVI_RS11230	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AVI_RS11235	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AVI_RS11245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AVI_RS11275	COG2264	protein methyltransferase activity
AVI_RS11280	COG1999	signal sequence binding
AVI_RS11285	COG0840	transmembrane signaling receptor activity
AVI_RS11290	COG0835	chemotaxis
AVI_RS11305	COG2176	DNA-directed DNA polymerase activity
AVI_RS11315	COG0840	transmembrane signaling receptor activity
AVI_RS11320	COG0456	acetyltransferase
AVI_RS11345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVI_RS11355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVI_RS11365	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVI_RS11375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AVI_RS11380	COG0849	cell division
AVI_RS11385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AVI_RS11390	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVI_RS11400	COG0477	Major facilitator Superfamily
AVI_RS11405	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVI_RS11410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVI_RS11415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AVI_RS11425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AVI_RS11430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVI_RS11440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVI_RS11455	COG0275	rRNA processing
AVI_RS11460	COG2001	Belongs to the MraZ family
AVI_RS11475	COG3023	N-Acetylmuramoyl-L-alanine amidase
AVI_RS11540	COG2226	methyltransferase
AVI_RS11545	COG0840	transmembrane signaling receptor activity
AVI_RS11550	COG0840	transmembrane signaling receptor activity
AVI_RS11565	COG2267	carboxylic ester hydrolase activity
AVI_RS11570	COG0697	spore germination
AVI_RS11575	COG0028	Belongs to the TPP enzyme family
AVI_RS11585	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AVI_RS11590	COG0251	oxidation-reduction process
AVI_RS11605	COG1376	ErfK ybiS ycfS ynhG family protein
AVI_RS11630	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AVI_RS11635	COG4149	molybdate abc transporter
AVI_RS11640	COG3842	ATPase activity
AVI_RS11655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVI_RS11670	COG1396	sequence-specific DNA binding
AVI_RS11730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVI_RS11735	COG0697	spore germination
AVI_RS11745	COG2968	Membrane
AVI_RS11825	COG4387	Mu-like prophage protein GP36
AVI_RS11835	COG4397	Mu-like prophage major head subunit gpT
AVI_RS11855	COG4383	Mu-like prophage protein gp29
AVI_RS11860	COG4373	Mu-like prophage FluMu protein gp28
AVI_RS12175	COG0443	Heat shock 70 kDa protein
AVI_RS12205	COG1278	Cold shock
AVI_RS12240	COG0432	Pfam Uncharacterised protein family UPF0047
AVI_RS12255	COG0583	DNA-binding transcription factor activity
AVI_RS12270	COG1473	amidohydrolase
AVI_RS12280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVI_RS12290	COG1268	BioY protein
AVI_RS12295	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AVI_RS12305	COG0505	Belongs to the CarA family
AVI_RS12310	COG0534	Mate efflux family protein
AVI_RS12315	COG0583	DNA-binding transcription factor activity
AVI_RS12320	COG0667	Aldo Keto reductase
AVI_RS12325	COG2321	neutral zinc metallopeptidase
AVI_RS12340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVI_RS12350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVI_RS12385	COG4641	Protein conserved in bacteria
AVI_RS12385	COG0438	transferase activity, transferring glycosyl groups
AVI_RS12390	COG1522	sequence-specific DNA binding
AVI_RS12395	COG0492	ferredoxin-NADP+ reductase activity
AVI_RS12400	COG0583	DNA-binding transcription factor activity
AVI_RS12405	COG0640	Transcriptional regulator
AVI_RS12410	COG1902	pentaerythritol trinitrate reductase activity
AVI_RS12430	COG0387	Pfam Sodium calcium exchanger
AVI_RS12440	COG0436	Aminotransferase
AVI_RS12455	COG1278	Cold shock
AVI_RS12460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVI_RS12470	COG1846	Transcriptional regulator
AVI_RS12475	COG0745	RESPONSE REGULATOR receiver
AVI_RS12480	COG2205	protein histidine kinase activity
AVI_RS12485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVI_RS12505	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AVI_RS12520	COG0006	proline dipeptidase activity
AVI_RS12535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVI_RS12550	COG1012	belongs to the aldehyde dehydrogenase family
AVI_RS12560	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AVI_RS12575	COG0193	aminoacyl-tRNA hydrolase activity
AVI_RS12590	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVI_RS12595	COG0012	GTP binding
AVI_RS12615	COG0386	Belongs to the glutathione peroxidase family
AVI_RS12625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVI_RS12630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AVI_RS12630	COG2857	Cytochrome c1
AVI_RS12655	COG1132	(ABC) transporter
AVI_RS12665	COG1132	(ABC) transporter
AVI_RS12670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AVI_RS12685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVI_RS12695	COG0408	coproporphyrinogen oxidase activity
AVI_RS12710	COG0617	tRNA 3'-terminal CCA addition
AVI_RS12725	COG0714	Associated with various cellular activities
AVI_RS12750	COG0454	-acetyltransferase
AVI_RS12770	COG0435	Glutathione S-transferase
AVI_RS12785	COG0740	serine-type endopeptidase activity
AVI_RS12790	COG3135	benzoate transporter
AVI_RS12795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVI_RS12845	COG0512	Glutamine amidotransferase of anthranilate synthase
AVI_RS12845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVI_RS12855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AVI_RS12860	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVI_RS12880	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AVI_RS12895	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AVI_RS12900	COG2197	response regulator
AVI_RS12915	COG1435	thymidine kinase activity
AVI_RS12930	COG4175	Glycine betaine
AVI_RS12950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AVI_RS12960	COG3293	Transposase
AVI_RS13000	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AVI_RS13010	COG4115	mRNA cleavage
AVI_RS13015	COG0366	Alpha amylase catalytic
AVI_RS13025	COG1160	GTP binding
AVI_RS13045	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AVI_RS13060	COG0024	Methionine aminopeptidase
AVI_RS13070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AVI_RS13075	COG1028	Short-chain dehydrogenase reductase Sdr
AVI_RS13085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVI_RS13095	COG0457	Tetratricopeptide repeat
AVI_RS13100	COG0583	DNA-binding transcription factor activity
AVI_RS13110	COG0402	S-adenosylhomocysteine deaminase activity
AVI_RS13115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVI_RS13125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVI_RS13130	COG0137	argininosuccinate synthase activity
AVI_RS13165	COG2351	hydroxyisourate hydrolase activity
AVI_RS13170	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AVI_RS13175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVI_RS13180	COG0174	glutamine synthetase
AVI_RS13190	COG3648	Uricase
AVI_RS13190	COG3195	allantoin biosynthetic process
AVI_RS13195	COG1064	alcohol dehydrogenase
AVI_RS13210	COG3706	GGDEF domain
AVI_RS13225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVI_RS13230	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVI_RS13230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVI_RS13245	COG0513	Belongs to the DEAD box helicase family
AVI_RS13260	COG1733	regulation of RNA biosynthetic process
AVI_RS13275	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVI_RS13285	COG1982	Orn Lys Arg decarboxylase major
AVI_RS13405	COG0686	Belongs to the AlaDH PNT family
AVI_RS13420	COG4372	Transposase
AVI_RS13425	COG3436	PFAM IS66 Orf2 family protein
AVI_RS13440	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AVI_RS13450	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AVI_RS13455	COG0028	Belongs to the TPP enzyme family
AVI_RS13455	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
AVI_RS13550	COG2308	Evidence 4 Homologs of previously reported genes of
AVI_RS13580	COG2346	COG2346, Truncated hemoglobins
AVI_RS13600	COG0493	'glutamate synthase
AVI_RS13620	COG1309	transcriptional regulator
AVI_RS13650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVI_RS13655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVI_RS13660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVI_RS13685	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AVI_RS13690	COG0830	nickel cation binding
AVI_RS13695	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AVI_RS13700	COG5001	Diguanylate cyclase
AVI_RS13700	COG5002	protein histidine kinase activity
AVI_RS13720	COG0804	urea catabolic process
AVI_RS13725	COG1442	glycosyl transferase family 8
AVI_RS13730	COG3755	Protein conserved in bacteria
AVI_RS13735	COG0832	Belongs to the urease beta subunit family
AVI_RS13740	COG3813	Protein conserved in bacteria
AVI_RS13745	COG0831	urea catabolic process
AVI_RS13750	COG0829	nickel cation binding
AVI_RS13795	COG4251	negative regulation of phosphorylation
AVI_RS13805	COG0784	Response regulator, receiver
AVI_RS13805	COG2205	protein histidine kinase activity
AVI_RS13820	COG0546	phosphoglycolate phosphatase activity
AVI_RS13855	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AVI_RS13860	COG2894	cell division
AVI_RS13865	COG0850	regulation of cytokinetic process
AVI_RS13905	COG2814	Major facilitator Superfamily
AVI_RS13920	COG1218	3'(2'),5'-bisphosphate nucleotidase
AVI_RS13975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVI_RS13985	COG0564	pseudouridine synthase activity
AVI_RS13990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVI_RS13990	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVI_RS13995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVI_RS14005	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AVI_RS14020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AVI_RS14035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVI_RS14055	COG1116	anion transmembrane transporter activity
AVI_RS14065	COG0402	S-adenosylhomocysteine deaminase activity
AVI_RS14075	COG2249	NAD(P)H dehydrogenase (quinone) activity
AVI_RS14100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AVI_RS14135	COG1175	transmembrane transport
AVI_RS14165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVI_RS14175	COG0482	sulfurtransferase activity
AVI_RS14185	COG4774	siderophore transport
AVI_RS14205	COG1120	ATPase activity
AVI_RS14215	COG4774	siderophore transport
AVI_RS14235	COG1294	oxidase, subunit
AVI_RS14240	COG1271	oxidase subunit
AVI_RS14245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVI_RS14270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVI_RS14275	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AVI_RS14280	COG0632	four-way junction helicase activity
AVI_RS14285	COG2002	toxin-antitoxin pair type II binding
AVI_RS14295	COG2255	four-way junction helicase activity
AVI_RS14300	COG1408	metallophosphoesterase
AVI_RS14305	COG0494	nUDIX hydrolase
AVI_RS14320	COG0824	Thioesterase
AVI_RS14340	COG0823	Involved in the tonB-independent uptake of proteins
AVI_RS14345	COG2885	chlorophyll binding
AVI_RS14355	COG0037	tRNA processing
AVI_RS14360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVI_RS14365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVI_RS14370	COG0217	transcriptional regulatory protein
AVI_RS14425	COG0840	transmembrane signaling receptor activity
AVI_RS14430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AVI_RS14435	COG1692	metallophosphoesterase
AVI_RS14440	COG0126	phosphoglycerate kinase activity
AVI_RS14445	COG3588	fructose-bisphosphate aldolase
AVI_RS14480	COG0254	rRNA binding
AVI_RS14485	COG1132	(ABC) transporter
AVI_RS14505	COG0483	inositol monophosphate 1-phosphatase activity
AVI_RS14515	COG0352	thiamine-phosphate diphosphorylase activity
AVI_RS14525	COG0640	Transcriptional regulator
AVI_RS14540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AVI_RS14545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AVI_RS14550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AVI_RS14560	COG0596	Alpha beta hydrolase
AVI_RS14565	COG0469	pyruvate kinase activity
AVI_RS14585	COG3750	Belongs to the UPF0335 family
AVI_RS14610	COG0512	Glutamine amidotransferase of anthranilate synthase
AVI_RS14610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVI_RS14615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVI_RS14630	COG5310	Homospermidine synthase
AVI_RS14645	COG0737	Belongs to the 5'-nucleotidase family
AVI_RS14650	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVI_RS14660	COG0840	transmembrane signaling receptor activity
AVI_RS14670	COG0602	queuosine metabolic process
AVI_RS14675	COG0720	synthase
AVI_RS14680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AVI_RS14685	COG0330	HflC and HflK could
AVI_RS14695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AVI_RS14695	COG0517	IMP dehydrogenase activity
AVI_RS14705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVI_RS14715	COG2951	lytic endotransglycosylase activity
AVI_RS14725	COG0840	transmembrane signaling receptor activity
AVI_RS14735	COG1487	ribonuclease activity
AVI_RS14745	COG0070	glutamate synthase
AVI_RS14745	COG0069	glutamate synthase activity
AVI_RS14745	COG0067	glutamate synthase
AVI_RS14760	COG0071	Belongs to the small heat shock protein (HSP20) family
AVI_RS14795	COG0668	transmembrane transport
AVI_RS14800	COG0662	Cupin 2, conserved barrel domain protein
AVI_RS14800	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AVI_RS14810	COG2308	Evidence 4 Homologs of previously reported genes of
AVI_RS14810	COG2307	Protein conserved in bacteria
AVI_RS14830	COG0058	SHG alpha-glucan phosphorylase activity
AVI_RS14835	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVI_RS14840	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AVI_RS14845	COG0297	glycogen (starch) synthase activity
AVI_RS14850	COG0033	Phosphoglucomutase
AVI_RS14890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AVI_RS14895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVI_RS14905	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVI_RS14905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVI_RS14920	COG1733	regulation of RNA biosynthetic process
AVI_RS14925	COG3041	Addiction module toxin RelE StbE family
AVI_RS14930	COG3077	Addiction module antitoxin, RelB DinJ family
AVI_RS14960	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AVI_RS14965	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AVI_RS14970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVI_RS14975	COG1609	Transcriptional regulator
AVI_RS14980	COG1846	Transcriptional regulator
AVI_RS14990	COG0523	cobalamin synthesis protein
AVI_RS15005	COG3047	cAMP biosynthetic process
AVI_RS15030	COG0583	DNA-binding transcription factor activity
AVI_RS15060	COG0800	Aldolase
AVI_RS15065	COG2954	triphosphatase activity
AVI_RS15075	COG2378	regulation of single-species biofilm formation
AVI_RS15085	COG1054	Belongs to the UPF0176 family
AVI_RS15090	COG2200	EAL domain
AVI_RS15090	COG2199	diguanylate cyclase activity
AVI_RS15090	COG2202	Pas domain
AVI_RS15110	COG0673	inositol 2-dehydrogenase activity
AVI_RS15120	COG2115	Belongs to the xylose isomerase family
AVI_RS15125	COG1070	Carbohydrate kinase
AVI_RS15130	COG1609	Transcriptional regulator
AVI_RS15145	COG1309	transcriptional regulator
AVI_RS15150	COG1253	flavin adenine dinucleotide binding
AVI_RS15170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVI_RS15190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AVI_RS15210	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVI_RS15215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVI_RS15220	COG0471	metal ion transport
AVI_RS15220	COG3273	potassium ion transport
AVI_RS15235	COG2274	protein secretion by the type I secretion system
AVI_RS15270	COG4172	Belongs to the ABC transporter superfamily
AVI_RS15275	COG1473	amidohydrolase
AVI_RS15290	COG0601	transmembrane transport
AVI_RS15295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVI_RS15300	COG0842	Transport permease protein
AVI_RS15305	COG1129	ABC transporter
AVI_RS15305	COG0842	Transport permease protein
AVI_RS15310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI_RS15320	COG3454	Phosphonate metabolism
AVI_RS15325	COG4608	Belongs to the ABC transporter superfamily
AVI_RS15330	COG0444	Belongs to the ABC transporter superfamily
AVI_RS15335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVI_RS15340	COG0601	transmembrane transport
AVI_RS15345	COG0747	negative chemotaxis
AVI_RS15355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVI_RS15360	COG1802	Transcriptional regulator
AVI_RS15365	COG1904	glucuronate isomerase
AVI_RS15370	COG1917	Cupin 2, conserved barrel domain protein
AVI_RS15380	COG1028	Short-chain dehydrogenase reductase Sdr
AVI_RS15385	COG0246	Mannitol dehydrogenase
AVI_RS15390	COG1312	Catalyzes the dehydration of D-mannonate
AVI_RS15395	COG2721	sulfolactate sulfo-lyase activity
AVI_RS15400	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AVI_RS15415	COG4213	ABC transporter substrate-binding protein
AVI_RS15420	COG1129	ABC transporter
AVI_RS15425	COG4214	carbohydrate transport
AVI_RS15435	COG0129	dihydroxy-acid dehydratase activity
AVI_RS15450	COG3734	2-keto-3-deoxy-galactonokinase
AVI_RS15455	COG0800	Aldolase
AVI_RS15460	COG2832	Protein of unknown function (DUF454)
AVI_RS15465	COG0697	spore germination
AVI_RS15470	COG2186	Transcriptional regulator
AVI_RS15475	COG2807	transmembrane transport
AVI_RS15480	COG2373	Large extracellular alpha-helical protein
AVI_RS15485	COG4953	penicillin-binding protein 1C
AVI_RS15490	COG2972	Histidine kinase
AVI_RS15490	COG0840	transmembrane signaling receptor activity
AVI_RS15495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVI_RS15505	COG0438	transferase activity, transferring glycosyl groups
AVI_RS15515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVI_RS15520	COG0601	transmembrane transport
AVI_RS15525	COG0747	negative chemotaxis
AVI_RS15545	COG0438	transferase activity, transferring glycosyl groups
AVI_RS15565	COG1132	(ABC) transporter
AVI_RS15575	COG0419	ATPase involved in DNA repair
AVI_RS15580	COG0840	transmembrane signaling receptor activity
AVI_RS15620	COG0542	response to heat
AVI_RS15630	COG2890	protein-(glutamine-N5) methyltransferase activity
AVI_RS15635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AVI_RS15645	COG0527	aspartate kinase activity
AVI_RS15665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVI_RS15680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVI_RS15685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVI_RS15695	COG2226	methyltransferase
AVI_RS15710	COG0494	nUDIX hydrolase
AVI_RS15720	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AVI_RS15725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVI_RS15730	COG0653	protein targeting
AVI_RS15745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVI_RS15755	COG2801	Transposase and inactivated derivatives
AVI_RS15780	COG0667	Aldo Keto reductase
AVI_RS15825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVI_RS15835	COG0300	oxidoreductase activity
AVI_RS15850	COG2086	electron transfer activity
AVI_RS15865	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVI_RS15870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVI_RS15875	COG0165	Argininosuccinate lyase
AVI_RS15885	COG0019	diaminopimelate decarboxylase activity
AVI_RS15900	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AVI_RS15910	COG2884	Cell division ATP-binding protein ftsE
AVI_RS15930	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AVI_RS15940	COG0287	Prephenate dehydrogenase
AVI_RS15945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVI_RS15950	COG2226	methyltransferase
AVI_RS15955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVI_RS15980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AVI_RS15985	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AVI_RS16015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVI_RS16020	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVI_RS16030	COG4974	Belongs to the 'phage' integrase family
AVI_RS16035	COG0825	malonyl-CoA metabolic process
AVI_RS16040	COG3034	peptidoglycan biosynthetic process
AVI_RS16050	COG0523	cobalamin synthesis protein
AVI_RS16055	COG1686	Belongs to the peptidase S11 family
AVI_RS16060	COG1473	amidohydrolase
AVI_RS16070	COG0628	permease
AVI_RS16080	COG2771	luxR family
AVI_RS16085	COG1766	The M ring may be actively involved in energy transduction
AVI_RS16095	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AVI_RS16100	COG0745	RESPONSE REGULATOR receiver
AVI_RS16105	COG2201	protein-glutamate methylesterase activity
AVI_RS16110	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVI_RS16115	COG0835	chemotaxis
AVI_RS16120	COG0643	Histidine kinase
AVI_RS16120	COG2198	Histidine kinase
AVI_RS16125	COG0745	RESPONSE REGULATOR receiver
AVI_RS16135	COG0840	transmembrane signaling receptor activity
AVI_RS16145	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AVI_RS16155	COG0156	8-amino-7-oxononanoate synthase activity
AVI_RS16165	COG0729	surface antigen
AVI_RS16180	COG0835	chemotaxis
AVI_RS16185	COG2223	nitrite transmembrane transporter activity
AVI_RS16195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AVI_RS16200	COG3383	formate dehydrogenase (NAD+) activity
AVI_RS16215	COG0583	DNA-binding transcription factor activity
AVI_RS16220	COG0640	Transcriptional regulator
AVI_RS16225	COG0039	L-malate dehydrogenase activity
AVI_RS16230	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AVI_RS16235	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AVI_RS16240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AVI_RS16245	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AVI_RS16250	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVI_RS16265	COG0840	transmembrane signaling receptor activity
AVI_RS16270	COG4974	Belongs to the 'phage' integrase family
AVI_RS16295	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVI_RS16305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AVI_RS16315	COG0045	succinate-CoA ligase (ADP-forming) activity
AVI_RS16320	COG0039	L-malate dehydrogenase activity
AVI_RS16325	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVI_RS16360	COG2264	protein methyltransferase activity
AVI_RS16375	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AVI_RS16380	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AVI_RS16385	COG0181	hydroxymethylbilane synthase activity
AVI_RS16425	COG1872	DUF167
AVI_RS16430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AVI_RS16440	COG1217	gtp-binding protein TYPA
AVI_RS16450	COG0339	signal peptide processing
AVI_RS16460	COG0137	argininosuccinate synthase activity
AVI_RS16475	COG1280	lysine exporter protein (LysE YggA)
AVI_RS16485	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AVI_RS16500	COG2154	pterin-4-alpha-carbinolamine dehydratase
AVI_RS16505	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AVI_RS16515	COG4181	ATPase activity
AVI_RS16520	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AVI_RS16525	COG0670	Belongs to the BI1 family
AVI_RS16550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AVI_RS16555	COG4133	protoheme IX ABC transporter activity
AVI_RS16560	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVI_RS16565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVI_RS16585	COG2917	probably involved in intracellular septation
AVI_RS16590	COG0552	protein localization to endoplasmic reticulum
AVI_RS16595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVI_RS16600	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVI_RS16615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVI_RS16620	COG1605	Chorismate mutase
AVI_RS16620	COG0287	Prephenate dehydrogenase
AVI_RS16625	COG0228	four-way junction DNA binding
AVI_RS16630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVI_RS16635	COG0336	Belongs to the RNA methyltransferase TrmD family
AVI_RS16645	COG0335	large ribosomal subunit rRNA binding
AVI_RS16660	COG2372	response to copper ion
AVI_RS16665	COG1276	copper resistance
AVI_RS16665	COG2372	response to copper ion
AVI_RS16670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVI_RS16675	COG0765	amino acid transport
AVI_RS16700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AVI_RS16715	COG0745	RESPONSE REGULATOR receiver
AVI_RS16735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AVI_RS16740	COG1674	ftsk spoiiie
AVI_RS16745	COG0004	ammonium transporteR
AVI_RS16750	COG0347	Belongs to the P(II) protein family
AVI_RS16755	COG1946	Acyl-CoA thioesterase
AVI_RS16760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVI_RS16765	COG2835	tetraacyldisaccharide 4'-kinase activity
AVI_RS16770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVI_RS16775	COG3118	belongs to the thioredoxin family
AVI_RS16795	COG2017	converts alpha-aldose to the beta-anomer
AVI_RS16810	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AVI_RS16815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVI_RS16825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AVI_RS16835	COG0488	(ABC) transporter
AVI_RS16865	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AVI_RS16900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVI_RS16905	COG0799	negative regulation of ribosome biogenesis
AVI_RS16910	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVI_RS16915	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AVI_RS16920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AVI_RS16925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AVI_RS16945	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AVI_RS16950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AVI_RS16970	COG0138	bifunctional purine biosynthesis protein purh
AVI_RS16980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVI_RS16980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVI_RS16985	COG0501	Belongs to the peptidase M48B family
AVI_RS17005	COG0793	Belongs to the peptidase S41A family
AVI_RS17015	COG0494	nUDIX hydrolase
AVI_RS17020	COG1192	Involved in chromosome partitioning
AVI_RS17045	COG2201	protein-glutamate methylesterase activity
AVI_RS17050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVI_RS17055	COG0835	chemotaxis
AVI_RS17060	COG0840	transmembrane signaling receptor activity
AVI_RS17065	COG0840	transmembrane signaling receptor activity
AVI_RS17065	COG3290	protein histidine kinase activity
AVI_RS17070	COG0840	transmembrane signaling receptor activity
AVI_RS17075	COG0835	chemotaxis
AVI_RS17080	COG2198	Histidine kinase
AVI_RS17080	COG0643	Histidine kinase
AVI_RS17085	COG0745	RESPONSE REGULATOR receiver
AVI_RS17110	COG1522	sequence-specific DNA binding
AVI_RS17120	COG4221	oxidoreductase activity
AVI_RS17125	COG0156	8-amino-7-oxononanoate synthase activity
AVI_RS17140	COG0738	Major facilitator superfamily
AVI_RS17145	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AVI_RS17150	COG2885	chlorophyll binding
AVI_RS17160	COG0142	geranyltranstransferase activity
AVI_RS17165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVI_RS17175	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AVI_RS17180	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AVI_RS17185	COG0183	Belongs to the thiolase family
AVI_RS17210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AVI_RS17230	COG2301	Belongs to the HpcH HpaI aldolase family
AVI_RS17240	COG0066	3-isopropylmalate dehydratase activity
AVI_RS17245	COG0473	3-isopropylmalate dehydrogenase activity
AVI_RS17250	COG0671	phosphoesterase, PA-phosphatase related
AVI_RS17260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AVI_RS17270	COG2010	Cytochrome c
AVI_RS17275	COG0288	reversible hydration of carbon dioxide
AVI_RS17280	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AVI_RS17285	COG2902	Dehydrogenase
AVI_RS17295	COG3459	Glycosyltransferase 36 associated
AVI_RS17300	COG1473	amidohydrolase
AVI_RS17315	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AVI_RS17325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVI_RS17335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AVI_RS17340	COG0495	leucyl-tRNA aminoacylation
AVI_RS17365	COG0357	Ribosomal RNA small subunit methyltransferase G
AVI_RS17370	COG0445	tRNA wobble uridine modification
AVI_RS17375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVI_RS17380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AVI_RS17385	COG1981	membrane
AVI_RS17390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AVI_RS18065	COG2814	Major facilitator Superfamily
AVI_RS18105	COG1185	polyribonucleotide nucleotidyltransferase activity
AVI_RS18260	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AVI_RS18475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI_RS18475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI_RS18485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI_RS18485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI_RS18500	COG0443	Heat shock 70 kDa protein
AVI_RS18675	COG1653	transport
AVI_RS18840	COG1420	regulation of RNA biosynthetic process
AVI_RS18985	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AVI_RS19180	COG0517	IMP dehydrogenase activity
AVI_RS19180	COG1125	glycine betaine transport
AVI_RS19555	COG1024	Enoyl-CoA hydratase
AVI_RS19555	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVI_RS19610	COG1785	Belongs to the alkaline phosphatase family
AVI_RS20365	COG0579	oxidoreductase
AVI_RS21000	COG0312	modulator of DNA gyrase
AVI_RS21920	COG1136	(ABC) transporter
AVI_RS21920	COG0577	efflux transmembrane transporter activity
AVI_RS22180	COG2205	protein histidine kinase activity
AVI_RS22195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AVI_RS22270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVI_RS22285	COG1028	Short-chain dehydrogenase reductase Sdr
AVI_RS22350	COG2239	Acts as a magnesium transporter
AVI_RS22570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVI_RS22950	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AVI_RS23075	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AVI_RS23080	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AVI_RS23125	COG1074	ATP-dependent DNA helicase activity
AVI_RS23145	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AVI_RS23195	COG1643	Atp-dependent helicase
AVI_RS23265	COG0673	inositol 2-dehydrogenase activity
AVI_RS23390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVI_RS23575	COG0285	dihydrofolate synthase activity
AVI_RS23840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVI_RS24050	COG2309	aminopeptidase activity
AVI_RS24205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AVI_RS24430	COG1132	(ABC) transporter
AVI_RS24610	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AVI_RS24725	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AVI_RS24820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVI_RS24920	COG3842	ATPase activity
AVI_RS24965	COG1605	Chorismate mutase
AVI_RS24965	COG0077	Prephenate dehydratase
AVI_RS25180	COG0195	Participates in both transcription termination and antitermination
AVI_RS25180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVI_RS25405	COG4964	Belongs to the GSP D family
AVI_RS25665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI_RS25665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVI_RS25955	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AVI_RS26705	COG1132	(ABC) transporter
AVI_RS27285	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AVI_RS28310	COG4372	Transposase
AVI_RS28470	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVI_RS28750	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AVI_RS28915	COG3962	Belongs to the TPP enzyme family
AVI_RS28970	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
AVI_RS28995	COG1404	Belongs to the peptidase S8 family
AVI_RS29045	COG3646	Phage regulatory protein
AVI_RS29080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVI_RS29100	COG2197	response regulator
AVI_RS29205	COG2972	Histidine kinase
AVI_RS29205	COG0840	transmembrane signaling receptor activity
AVI_RS29320	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVI_RS29345	COG2813	Specifically methylates the guanine in position