locus-tag	class	description
RvVAT039_RS00005	COG0400	carboxylic ester hydrolase activity
RvVAT039_RS00025	COG3307	-O-antigen
RvVAT039_RS00030	COG1596	polysaccharide export
RvVAT039_RS00035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RvVAT039_RS00045	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_RS00050	COG2327	Polysaccharide pyruvyl transferase
RvVAT039_RS00055	COG0463	Glycosyl transferase, family 2
RvVAT039_RS00060	COG2244	polysaccharide biosynthetic process
RvVAT039_RS00065	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RvVAT039_RS00070	COG2273	Hydrolase Family 16
RvVAT039_RS00075	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_RS00080	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_RS00085	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_RS00090	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_RS00095	COG3206	protein involved in exopolysaccharide biosynthesis
RvVAT039_RS00095	COG0489	protein tyrosine kinase activity
RvVAT039_RS00100	COG0469	pyruvate kinase activity
RvVAT039_RS00140	COG0542	response to heat
RvVAT039_RS00150	COG2890	protein-(glutamine-N5) methyltransferase activity
RvVAT039_RS00155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RvVAT039_RS00165	COG0527	aspartate kinase activity
RvVAT039_RS00185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RvVAT039_RS00200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RvVAT039_RS00205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RvVAT039_RS00210	COG1040	competence protein
RvVAT039_RS00215	COG2226	methyltransferase
RvVAT039_RS00230	COG0494	nUDIX hydrolase
RvVAT039_RS00240	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RvVAT039_RS00245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RvVAT039_RS00250	COG0653	protein targeting
RvVAT039_RS00265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RvVAT039_RS00305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RvVAT039_RS00315	COG0300	oxidoreductase activity
RvVAT039_RS00330	COG2086	electron transfer activity
RvVAT039_RS00340	COG0840	transmembrane signaling receptor activity
RvVAT039_RS00340	COG2972	Histidine kinase
RvVAT039_RS00345	COG1250	3-hydroxyacyl-CoA dehydrogenase
RvVAT039_RS00350	COG0625	glutathione transferase activity
RvVAT039_RS00355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RvVAT039_RS00360	COG0165	Argininosuccinate lyase
RvVAT039_RS00370	COG0019	diaminopimelate decarboxylase activity
RvVAT039_RS00400	COG2884	Cell division ATP-binding protein ftsE
RvVAT039_RS00420	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
RvVAT039_RS00430	COG0287	Prephenate dehydrogenase
RvVAT039_RS00435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RvVAT039_RS00440	COG2226	methyltransferase
RvVAT039_RS00445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RvVAT039_RS00470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RvVAT039_RS00475	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RvVAT039_RS00505	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RvVAT039_RS00510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RvVAT039_RS00525	COG4974	Belongs to the 'phage' integrase family
RvVAT039_RS00530	COG0825	malonyl-CoA metabolic process
RvVAT039_RS00535	COG3034	peptidoglycan biosynthetic process
RvVAT039_RS00545	COG0523	cobalamin synthesis protein
RvVAT039_RS00550	COG1686	Belongs to the peptidase S11 family
RvVAT039_RS00555	COG1473	amidohydrolase
RvVAT039_RS00565	COG0628	permease
RvVAT039_RS00575	COG2771	luxR family
RvVAT039_RS00580	COG1766	The M ring may be actively involved in energy transduction
RvVAT039_RS00590	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RvVAT039_RS00595	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS00600	COG2201	protein-glutamate methylesterase activity
RvVAT039_RS00605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RvVAT039_RS00610	COG0835	chemotaxis
RvVAT039_RS00615	COG2198	Histidine kinase
RvVAT039_RS00615	COG0643	Histidine kinase
RvVAT039_RS00620	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS00630	COG0840	transmembrane signaling receptor activity
RvVAT039_RS00635	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RvVAT039_RS00645	COG0156	8-amino-7-oxononanoate synthase activity
RvVAT039_RS00655	COG0729	surface antigen
RvVAT039_RS00670	COG0835	chemotaxis
RvVAT039_RS00675	COG2223	nitrite transmembrane transporter activity
RvVAT039_RS00685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RvVAT039_RS00690	COG3383	formate dehydrogenase (NAD+) activity
RvVAT039_RS00705	COG0583	DNA-binding transcription factor activity
RvVAT039_RS00710	COG0640	Transcriptional regulator
RvVAT039_RS00715	COG0039	L-malate dehydrogenase activity
RvVAT039_RS00720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RvVAT039_RS00725	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RvVAT039_RS00730	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RvVAT039_RS00735	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RvVAT039_RS00740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RvVAT039_RS00755	COG0840	transmembrane signaling receptor activity
RvVAT039_RS00755	COG2972	Histidine kinase
RvVAT039_RS00765	COG4974	Belongs to the 'phage' integrase family
RvVAT039_RS00780	COG1280	lysine exporter protein (LysE YggA)
RvVAT039_RS00790	COG0508	dehydrogenase complex catalyzes the overall conversion of
RvVAT039_RS00800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RvVAT039_RS00810	COG0045	succinate-CoA ligase (ADP-forming) activity
RvVAT039_RS00815	COG0039	L-malate dehydrogenase activity
RvVAT039_RS00820	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RvVAT039_RS00865	COG2350	Protein conserved in bacteria
RvVAT039_RS00870	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RvVAT039_RS00875	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RvVAT039_RS00880	COG0181	hydroxymethylbilane synthase activity
RvVAT039_RS00920	COG1872	DUF167
RvVAT039_RS00925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RvVAT039_RS00945	COG0339	signal peptide processing
RvVAT039_RS00955	COG0137	argininosuccinate synthase activity
RvVAT039_RS00960	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS00970	COG1280	lysine exporter protein (LysE YggA)
RvVAT039_RS00980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RvVAT039_RS00995	COG2154	pterin-4-alpha-carbinolamine dehydratase
RvVAT039_RS01000	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RvVAT039_RS01010	COG1136	(ABC) transporter
RvVAT039_RS01015	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RvVAT039_RS01020	COG0670	Belongs to the BI1 family
RvVAT039_RS01040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RvVAT039_RS01045	COG4133	protoheme IX ABC transporter activity
RvVAT039_RS01050	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RvVAT039_RS01055	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RvVAT039_RS01075	COG2917	probably involved in intracellular septation
RvVAT039_RS01080	COG0552	protein localization to endoplasmic reticulum
RvVAT039_RS01085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RvVAT039_RS01090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RvVAT039_RS01105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RvVAT039_RS01110	COG1605	Chorismate mutase
RvVAT039_RS01110	COG0287	Prephenate dehydrogenase
RvVAT039_RS01115	COG0228	four-way junction DNA binding
RvVAT039_RS01120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RvVAT039_RS01125	COG0336	Belongs to the RNA methyltransferase TrmD family
RvVAT039_RS01135	COG0335	large ribosomal subunit rRNA binding
RvVAT039_RS01150	COG2372	response to copper ion
RvVAT039_RS01155	COG1276	copper resistance
RvVAT039_RS01160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_RS01165	COG0765	amino acid transport
RvVAT039_RS01180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RvVAT039_RS01195	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS01215	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RvVAT039_RS01220	COG1674	ftsk spoiiie
RvVAT039_RS01225	COG0004	ammonium transporteR
RvVAT039_RS01230	COG0347	Belongs to the P(II) protein family
RvVAT039_RS01235	COG1946	Acyl-CoA thioesterase
RvVAT039_RS01240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RvVAT039_RS01245	COG2835	tetraacyldisaccharide 4'-kinase activity
RvVAT039_RS01250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RvVAT039_RS01255	COG3118	belongs to the thioredoxin family
RvVAT039_RS01275	COG2017	converts alpha-aldose to the beta-anomer
RvVAT039_RS01290	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RvVAT039_RS01310	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RvVAT039_RS01350	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
RvVAT039_RS01380	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RvVAT039_RS01385	COG0799	negative regulation of ribosome biogenesis
RvVAT039_RS01390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RvVAT039_RS01395	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RvVAT039_RS01400	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RvVAT039_RS01405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RvVAT039_RS01425	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RvVAT039_RS01430	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RvVAT039_RS01440	COG4650	regulator
RvVAT039_RS01470	COG0138	bifunctional purine biosynthesis protein purh
RvVAT039_RS01480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RvVAT039_RS01480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RvVAT039_RS01485	COG0501	Belongs to the peptidase M48B family
RvVAT039_RS01505	COG0793	Belongs to the peptidase S41A family
RvVAT039_RS01515	COG0494	nUDIX hydrolase
RvVAT039_RS01545	COG2201	protein-glutamate methylesterase activity
RvVAT039_RS01550	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RvVAT039_RS01555	COG0835	chemotaxis
RvVAT039_RS01560	COG0840	transmembrane signaling receptor activity
RvVAT039_RS01565	COG0840	transmembrane signaling receptor activity
RvVAT039_RS01565	COG3290	protein histidine kinase activity
RvVAT039_RS01570	COG0840	transmembrane signaling receptor activity
RvVAT039_RS01575	COG0835	chemotaxis
RvVAT039_RS01580	COG2198	Histidine kinase
RvVAT039_RS01580	COG0643	Histidine kinase
RvVAT039_RS01585	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS01610	COG1522	sequence-specific DNA binding
RvVAT039_RS01625	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
RvVAT039_RS01630	COG0156	8-amino-7-oxononanoate synthase activity
RvVAT039_RS01640	COG0738	Major facilitator superfamily
RvVAT039_RS01645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RvVAT039_RS01650	COG2885	chlorophyll binding
RvVAT039_RS01660	COG0142	geranyltranstransferase activity
RvVAT039_RS01665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RvVAT039_RS01675	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RvVAT039_RS01680	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
RvVAT039_RS01715	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RvVAT039_RS01735	COG2301	Belongs to the HpcH HpaI aldolase family
RvVAT039_RS01745	COG0066	3-isopropylmalate dehydratase activity
RvVAT039_RS01750	COG0473	3-isopropylmalate dehydrogenase activity
RvVAT039_RS01755	COG0671	phosphoesterase, PA-phosphatase related
RvVAT039_RS01765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RvVAT039_RS01775	COG2010	Cytochrome c
RvVAT039_RS01780	COG0288	reversible hydration of carbon dioxide
RvVAT039_RS01785	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
RvVAT039_RS01790	COG2902	Dehydrogenase
RvVAT039_RS01800	COG3459	Glycosyltransferase 36 associated
RvVAT039_RS01805	COG1473	amidohydrolase
RvVAT039_RS01820	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RvVAT039_RS01830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RvVAT039_RS01840	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RvVAT039_RS01845	COG0495	leucyl-tRNA aminoacylation
RvVAT039_RS01870	COG0357	Ribosomal RNA small subunit methyltransferase G
RvVAT039_RS01875	COG0445	tRNA wobble uridine modification
RvVAT039_RS01880	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RvVAT039_RS01885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RvVAT039_RS01895	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RvVAT039_RS01900	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RvVAT039_RS01905	COG0424	maF-like protein
RvVAT039_RS01910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RvVAT039_RS01915	COG0237	dephospho-CoA kinase activity
RvVAT039_RS01925	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
RvVAT039_RS01940	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RvVAT039_RS01980	COG0135	phosphoribosylanthranilate isomerase activity
RvVAT039_RS01985	COG0133	tryptophan synthase activity
RvVAT039_RS01990	COG0159	tryptophan synthase activity
RvVAT039_RS01995	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RvVAT039_RS02000	COG0285	dihydrofolate synthase activity
RvVAT039_RS02025	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RvVAT039_RS02030	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RvVAT039_RS02035	COG0131	Imidazoleglycerol-phosphate dehydratase
RvVAT039_RS02040	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RvVAT039_RS02045	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RvVAT039_RS02050	COG0107	imidazoleglycerol-phosphate synthase activity
RvVAT039_RS02055	COG0140	phosphoribosyl-ATP diphosphatase activity
RvVAT039_RS02060	COG1072	(Pantothenic acid kinase))
RvVAT039_RS02075	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
RvVAT039_RS02080	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS02085	COG0642	Histidine kinase
RvVAT039_RS02095	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RvVAT039_RS02095	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RvVAT039_RS02100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RvVAT039_RS02105	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RvVAT039_RS02110	COG2205	protein histidine kinase activity
RvVAT039_RS02115	COG3178	'Phosphotransferase
RvVAT039_RS02120	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RvVAT039_RS02135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RvVAT039_RS02150	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
RvVAT039_RS02160	COG1643	Atp-dependent helicase
RvVAT039_RS02165	COG2423	ornithine cyclodeaminase activity
RvVAT039_RS02205	COG2814	Major facilitator Superfamily
RvVAT039_RS02210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RvVAT039_RS02215	COG1609	Transcriptional regulator
RvVAT039_RS02225	COG0673	inositol 2-dehydrogenase activity
RvVAT039_RS02235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RvVAT039_RS02240	COG3962	Belongs to the TPP enzyme family
RvVAT039_RS02255	COG3718	enzyme involved in inositol metabolism
RvVAT039_RS02280	COG4221	oxidoreductase activity
RvVAT039_RS02285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RvVAT039_RS02300	COG1595	DNA-templated transcription, initiation
RvVAT039_RS02305	COG3806	Anti-sigma factor
RvVAT039_RS02325	COG3842	ATPase activity
RvVAT039_RS02330	COG3842	ATPase activity
RvVAT039_RS02340	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS02360	COG3474	cytochrome
RvVAT039_RS02365	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
RvVAT039_RS02370	COG1605	Chorismate mutase
RvVAT039_RS02370	COG0077	Prephenate dehydratase
RvVAT039_RS02380	COG2816	NAD+ diphosphatase activity
RvVAT039_RS02395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RvVAT039_RS02400	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RvVAT039_RS02410	COG3422	double-strand break repair
RvVAT039_RS02425	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RvVAT039_RS02430	COG0481	GTPase activity
RvVAT039_RS02445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RvVAT039_RS02450	COG1607	acyl-coa hydrolase
RvVAT039_RS02475	COG1393	Belongs to the ArsC family
RvVAT039_RS02480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RvVAT039_RS02485	COG2309	aminopeptidase activity
RvVAT039_RS02500	COG1278	Cold shock
RvVAT039_RS02505	COG1570	exodeoxyribonuclease VII activity
RvVAT039_RS02545	COG0667	Aldo Keto reductase
RvVAT039_RS02565	COG2814	Major facilitator Superfamily
RvVAT039_RS02570	COG0583	DNA-binding transcription factor activity
RvVAT039_RS02580	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RvVAT039_RS02585	COG2951	lytic endotransglycosylase activity
RvVAT039_RS02610	COG2814	Major facilitator Superfamily
RvVAT039_RS02615	COG0779	Required for maturation of 30S ribosomal subunits
RvVAT039_RS02620	COG0195	Participates in both transcription termination and antitermination
RvVAT039_RS02620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RvVAT039_RS02630	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RvVAT039_RS02635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RvVAT039_RS02640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RvVAT039_RS02645	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RvVAT039_RS02650	COG1185	polyribonucleotide nucleotidyltransferase activity
RvVAT039_RS02655	COG2813	Specifically methylates the guanine in position
RvVAT039_RS02660	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RvVAT039_RS02670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RvVAT039_RS02680	COG2860	membrane
RvVAT039_RS02690	COG0477	Major facilitator Superfamily
RvVAT039_RS02705	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RvVAT039_RS02710	COG0539	negative regulation of cytoplasmic translation
RvVAT039_RS02735	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RvVAT039_RS02745	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS02750	COG2205	protein histidine kinase activity
RvVAT039_RS02755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RvVAT039_RS02760	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RvVAT039_RS02765	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RvVAT039_RS02775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RvVAT039_RS02775	COG0072	phenylalanine-tRNA ligase activity
RvVAT039_RS02820	COG4964	Belongs to the GSP D family
RvVAT039_RS02860	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RvVAT039_RS02865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RvVAT039_RS02870	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RvVAT039_RS02880	COG0588	phosphoglycerate mutase activity
RvVAT039_RS02885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RvVAT039_RS02890	COG1132	(ABC) transporter
RvVAT039_RS02895	COG0837	glucose binding
RvVAT039_RS02900	COG1803	Methylglyoxal synthase
RvVAT039_RS02905	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
RvVAT039_RS02910	COG4166	transmembrane transport
RvVAT039_RS02915	COG4174	ABC transporter (Permease)
RvVAT039_RS02920	COG4239	(ABC) transporter, permease
RvVAT039_RS02925	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_RS02930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RvVAT039_RS02940	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RvVAT039_RS02950	COG0604	alcohol dehydrogenase
RvVAT039_RS03000	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RvVAT039_RS03005	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
RvVAT039_RS03010	COG2188	Transcriptional regulator
RvVAT039_RS03015	COG3624	Phosphonate C-P lyase system protein PhnG
RvVAT039_RS03020	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
RvVAT039_RS03025	COG3626	phosphonate metabolism
RvVAT039_RS03030	COG3627	carbon phosphorus lyase activity
RvVAT039_RS03035	COG4107	phosphonate C-P lyase system protein PhnK
RvVAT039_RS03040	COG4778	phosphonate C-P lyase system protein PhnL
RvVAT039_RS03050	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RvVAT039_RS03055	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
RvVAT039_RS03065	COG3639	organic phosphonate transmembrane transporter activity
RvVAT039_RS03070	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
RvVAT039_RS03075	COG3454	Phosphonate metabolism
RvVAT039_RS03080	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
RvVAT039_RS03090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RvVAT039_RS03095	COG2353	YceI-like domain
RvVAT039_RS03100	COG2353	YceI-like domain
RvVAT039_RS03110	COG0791	NLP P60 protein
RvVAT039_RS03120	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RvVAT039_RS03120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RvVAT039_RS03130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_RS03135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RvVAT039_RS03150	COG0443	Heat shock 70 kDa protein
RvVAT039_RS03160	COG0484	heat shock protein binding
RvVAT039_RS03165	COG2900	Belongs to the SlyX family
RvVAT039_RS03170	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RvVAT039_RS03185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RvVAT039_RS03195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RvVAT039_RS03200	COG5001	Diguanylate cyclase
RvVAT039_RS03205	COG3002	Belongs to the UPF0753 family
RvVAT039_RS03210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RvVAT039_RS03235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RvVAT039_RS03235	COG0519	Catalyzes the synthesis of GMP from XMP
RvVAT039_RS03250	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
RvVAT039_RS03275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RvVAT039_RS03275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RvVAT039_RS03280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RvVAT039_RS03290	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RvVAT039_RS03300	COG1968	undecaprenyl-diphosphatase activity
RvVAT039_RS03320	COG0284	orotidine-5'-phosphate decarboxylase activity
RvVAT039_RS03330	COG3963	phosphatidate phosphatase activity
RvVAT039_RS03340	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RvVAT039_RS03345	COG0792	nuclease activity
RvVAT039_RS03350	COG1653	transport
RvVAT039_RS03360	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS03365	COG3842	ATPase activity
RvVAT039_RS03375	COG0189	ligase activity
RvVAT039_RS03380	COG0606	chelatase, subunit chli
RvVAT039_RS03395	COG1280	lysine exporter protein (LysE YggA)
RvVAT039_RS03400	COG0756	dUTP diphosphatase activity
RvVAT039_RS03405	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
RvVAT039_RS03410	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RvVAT039_RS03415	COG1877	trehalose-phosphatase activity
RvVAT039_RS03435	COG1741	Belongs to the pirin family
RvVAT039_RS03450	COG0583	DNA-binding transcription factor activity
RvVAT039_RS03465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RvVAT039_RS03470	COG3920	Histidine kinase
RvVAT039_RS03475	COG0784	Response regulator, receiver
RvVAT039_RS03480	COG0784	Response regulator, receiver
RvVAT039_RS03480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_RS03480	COG2198	Histidine kinase
RvVAT039_RS03480	COG2205	protein histidine kinase activity
RvVAT039_RS03485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RvVAT039_RS03490	COG2226	methyltransferase
RvVAT039_RS03495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RvVAT039_RS03500	COG0268	Binds directly to 16S ribosomal RNA
RvVAT039_RS03510	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RvVAT039_RS03515	COG0697	spore germination
RvVAT039_RS03520	COG2226	methyltransferase
RvVAT039_RS03525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RvVAT039_RS03530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RvVAT039_RS03540	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RvVAT039_RS03545	COG1420	regulation of RNA biosynthetic process
RvVAT039_RS03550	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RvVAT039_RS03555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RvVAT039_RS03560	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RvVAT039_RS03570	COG1137	ATPase activity
RvVAT039_RS03575	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
RvVAT039_RS03585	COG0776	regulation of translation
RvVAT039_RS03595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RvVAT039_RS03595	COG0116	Belongs to the methyltransferase superfamily
RvVAT039_RS03600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RvVAT039_RS03605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RvVAT039_RS03620	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RvVAT039_RS03625	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RvVAT039_RS03635	COG0346	lactoylglutathione lyase activity
RvVAT039_RS03640	COG0180	Tryptophanyl-tRNA synthetase
RvVAT039_RS03650	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RvVAT039_RS03655	COG1214	PFAM Peptidase M22, glycoprotease
RvVAT039_RS03675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RvVAT039_RS03680	COG1702	phosphate starvation-inducible protein PhoH
RvVAT039_RS03685	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RvVAT039_RS03690	COG4535	Mg2 and Co2 transporter CorC
RvVAT039_RS03695	COG0815	Transfers the fatty acyl group on membrane lipoproteins
RvVAT039_RS03700	COG1396	sequence-specific DNA binding
RvVAT039_RS03705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RvVAT039_RS03710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RvVAT039_RS03720	COG0071	Belongs to the small heat shock protein (HSP20) family
RvVAT039_RS03740	COG0840	transmembrane signaling receptor activity
RvVAT039_RS03760	COG2205	protein histidine kinase activity
RvVAT039_RS03765	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RvVAT039_RS03770	COG0594	ribonuclease P activity
RvVAT039_RS03775	COG0706	membrane insertase activity
RvVAT039_RS03780	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RvVAT039_RS03785	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
RvVAT039_RS03800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RvVAT039_RS03805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RvVAT039_RS03830	COG2171	N-acyltransferase activity
RvVAT039_RS03835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_RS03860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RvVAT039_RS03865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RvVAT039_RS03875	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS03880	COG0704	Plays a role in the regulation of phosphate uptake
RvVAT039_RS03885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RvVAT039_RS03895	COG0573	inorganic phosphate transmembrane transporter activity
RvVAT039_RS03905	COG5002	protein histidine kinase activity
RvVAT039_RS03910	COG2326	polyphosphate kinase activity
RvVAT039_RS03935	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RvVAT039_RS03940	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RvVAT039_RS03950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RvVAT039_RS03970	COG0427	acetyl-CoA hydrolase
RvVAT039_RS03980	COG3938	Belongs to the proline racemase family
RvVAT039_RS03985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RvVAT039_RS03990	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS04010	COG0418	dihydroorotase activity
RvVAT039_RS04015	COG3706	GGDEF domain
RvVAT039_RS04020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RvVAT039_RS04035	COG0166	Belongs to the GPI family
RvVAT039_RS04040	COG0318	PFAM AMP-dependent synthetase and ligase
RvVAT039_RS04055	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS04065	COG0101	tRNA pseudouridine synthase activity
RvVAT039_RS04070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RvVAT039_RS04075	COG0242	peptide deformylase activity
RvVAT039_RS04080	COG2967	ApaG domain
RvVAT039_RS04090	COG0717	Belongs to the dCTP deaminase family
RvVAT039_RS04130	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
RvVAT039_RS04135	COG0732	type I restriction modification DNA specificity domain
RvVAT039_RS04155	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
RvVAT039_RS04165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_RS04205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_RS04230	COG0167	dihydroorotate dehydrogenase activity
RvVAT039_RS04270	COG1250	3-hydroxyacyl-CoA dehydrogenase
RvVAT039_RS04270	COG1024	Enoyl-CoA hydratase
RvVAT039_RS04275	COG0183	Belongs to the thiolase family
RvVAT039_RS04280	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_RS04300	COG1785	Belongs to the alkaline phosphatase family
RvVAT039_RS04310	COG1136	(ABC) transporter
RvVAT039_RS04325	COG2203	Gaf domain
RvVAT039_RS04325	COG3706	GGDEF domain
RvVAT039_RS04325	COG4251	negative regulation of phosphorylation
RvVAT039_RS04325	COG5001	Diguanylate cyclase
RvVAT039_RS04330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RvVAT039_RS04340	COG1201	RNA secondary structure unwinding
RvVAT039_RS04360	COG1047	Peptidyl-prolyl cis-trans
RvVAT039_RS04365	COG0784	Response regulator, receiver
RvVAT039_RS04365	COG2205	protein histidine kinase activity
RvVAT039_RS04365	COG2198	Histidine kinase
RvVAT039_RS04370	COG1970	mechanosensitive ion channel activity
RvVAT039_RS04375	COG0436	Aminotransferase
RvVAT039_RS04385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RvVAT039_RS04430	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
RvVAT039_RS04435	COG0424	maF-like protein
RvVAT039_RS04440	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RvVAT039_RS04450	COG5328	Belongs to the UPF0262 family
RvVAT039_RS04455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RvVAT039_RS04465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RvVAT039_RS04500	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_RS04510	COG0488	(ABC) transporter
RvVAT039_RS04535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RvVAT039_RS04540	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RvVAT039_RS04545	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RvVAT039_RS04550	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RvVAT039_RS04555	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RvVAT039_RS04560	COG4786	Flagellar basal body rod
RvVAT039_RS04565	COG1157	protein secretion by the type III secretion system
RvVAT039_RS04575	COG1815	bacterial-type flagellum-dependent cell motility
RvVAT039_RS04580	COG1558	bacterial-type flagellum-dependent cell motility
RvVAT039_RS04585	COG1677	Flagellar hook-basal body complex protein FliE
RvVAT039_RS04590	COG4786	Flagellar basal body rod
RvVAT039_RS04595	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
RvVAT039_RS04600	COG1706	bacterial-type flagellum-dependent cell motility
RvVAT039_RS04610	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
RvVAT039_RS04620	COG1338	Plays a role in the flagellum-specific transport system
RvVAT039_RS04625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_RS04630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_RS04635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_RS04640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_RS04645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_RS04655	COG1360	Flagellar Motor Protein
RvVAT039_RS04680	COG1749	Flagellar hook protein flgE
RvVAT039_RS04700	COG5443	negative regulation of bacterial-type flagellum assembly
RvVAT039_RS04705	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RvVAT039_RS04710	COG4794	Type iii secretion
RvVAT039_RS04715	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RvVAT039_RS04750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RvVAT039_RS04755	COG1609	Transcriptional regulator
RvVAT039_RS04760	COG1653	transport
RvVAT039_RS04765	COG1175	transmembrane transport
RvVAT039_RS04770	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS04775	COG0366	Alpha amylase catalytic
RvVAT039_RS04780	COG3842	ATPase activity
RvVAT039_RS04795	COG3493	citrate carrier protein
RvVAT039_RS04805	COG0129	dihydroxy-acid dehydratase activity
RvVAT039_RS04810	COG0363	glucosamine-6-phosphate deaminase activity
RvVAT039_RS04815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RvVAT039_RS04825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_RS04835	COG2081	HI0933 family
RvVAT039_RS04850	COG2972	Histidine kinase
RvVAT039_RS04850	COG0840	transmembrane signaling receptor activity
RvVAT039_RS04875	COG2224	Isocitrate lyase
RvVAT039_RS04895	COG3842	ATPase activity
RvVAT039_RS04900	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_RS04905	COG1177	transmembrane transport
RvVAT039_RS04915	COG2205	protein histidine kinase activity
RvVAT039_RS04965	COG1959	2 iron, 2 sulfur cluster binding
RvVAT039_RS04970	COG3265	gluconokinase activity
RvVAT039_RS04985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_RS04990	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RvVAT039_RS05010	COG0579	oxidoreductase
RvVAT039_RS05025	COG0248	Ppx GppA phosphatase
RvVAT039_RS05030	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
RvVAT039_RS05040	COG5001	Diguanylate cyclase
RvVAT039_RS05040	COG3300	MHYT domain
RvVAT039_RS05045	COG0784	Response regulator, receiver
RvVAT039_RS05045	COG5002	protein histidine kinase activity
RvVAT039_RS05045	COG2198	Histidine kinase
RvVAT039_RS05050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RvVAT039_RS05060	COG1663	tetraacyldisaccharide 4'-kinase activity
RvVAT039_RS05070	COG1519	Transferase
RvVAT039_RS05080	COG1218	3'(2'),5'-bisphosphate nucleotidase
RvVAT039_RS05085	COG0312	modulator of DNA gyrase
RvVAT039_RS05090	COG0475	glutathione-regulated potassium exporter activity
RvVAT039_RS05090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RvVAT039_RS05100	COG0742	ribosomal rna small subunit methyltransferase
RvVAT039_RS05105	COG1187	pseudouridine synthase activity
RvVAT039_RS05110	COG0590	tRNA wobble adenosine to inosine editing
RvVAT039_RS05120	COG0477	Major facilitator Superfamily
RvVAT039_RS05130	COG3386	PFAM SMP-30 Gluconolaconase
RvVAT039_RS05135	COG2771	luxR family
RvVAT039_RS05155	COG3158	transport of potassium into the cell
RvVAT039_RS05165	COG0356	it plays a direct role in the translocation of protons across the membrane
RvVAT039_RS05175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RvVAT039_RS05180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RvVAT039_RS05185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RvVAT039_RS05200	COG0521	Mo-molybdopterin cofactor biosynthetic process
RvVAT039_RS05205	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RvVAT039_RS05215	COG0142	geranyltranstransferase activity
RvVAT039_RS05225	COG4106	trans-aconitate 2-methyltransferase activity
RvVAT039_RS05245	COG0752	glycyl-tRNA synthetase alpha subunit
RvVAT039_RS05255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RvVAT039_RS05260	COG0751	glycine-tRNA ligase activity
RvVAT039_RS05265	COG1683	Conserved Protein
RvVAT039_RS05270	COG0840	transmembrane signaling receptor activity
RvVAT039_RS05270	COG0840	transmembrane signaling receptor activity
RvVAT039_RS05280	COG0151	Belongs to the GarS family
RvVAT039_RS05290	COG2183	response to ionizing radiation
RvVAT039_RS05295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RvVAT039_RS05300	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RvVAT039_RS05325	COG0725	ABC transporter, periplasmic molybdate-binding protein
RvVAT039_RS05330	COG4149	molybdate abc transporter
RvVAT039_RS05335	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RvVAT039_RS05340	COG3585	molybdate ion transport
RvVAT039_RS05340	COG2005	Transcriptional regulator
RvVAT039_RS05350	COG0009	L-threonylcarbamoyladenylate synthase
RvVAT039_RS05360	COG0840	transmembrane signaling receptor activity
RvVAT039_RS05360	COG2972	Histidine kinase
RvVAT039_RS05375	COG4638	Rieske (2fe-2S)
RvVAT039_RS05400	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_RS05405	COG1024	Enoyl-CoA hydratase
RvVAT039_RS05420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RvVAT039_RS05425	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RvVAT039_RS05430	COG0840	transmembrane signaling receptor activity
RvVAT039_RS05435	COG0840	transmembrane signaling receptor activity
RvVAT039_RS05440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RvVAT039_RS05445	COG1722	exodeoxyribonuclease VII activity
RvVAT039_RS05450	COG0123	including yeast histone deacetylase and acetoin utilization protein
RvVAT039_RS05465	COG1268	BioY protein
RvVAT039_RS05470	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RvVAT039_RS05475	COG1122	ATPase activity
RvVAT039_RS05485	COG3214	Protein conserved in bacteria
RvVAT039_RS05505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RvVAT039_RS05505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RvVAT039_RS05510	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RvVAT039_RS05515	COG3300	MHYT domain
RvVAT039_RS05515	COG5001	Diguanylate cyclase
RvVAT039_RS05530	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RvVAT039_RS05535	COG0484	heat shock protein binding
RvVAT039_RS05545	COG0259	pyridoxamine-phosphate oxidase activity
RvVAT039_RS05555	COG2814	Major facilitator Superfamily
RvVAT039_RS05565	COG1686	Belongs to the peptidase S11 family
RvVAT039_RS05580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RvVAT039_RS05590	COG0312	modulator of DNA gyrase
RvVAT039_RS05605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RvVAT039_RS05610	COG0109	protoheme IX farnesyltransferase activity
RvVAT039_RS05620	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
RvVAT039_RS05635	COG3346	SURF1 family
RvVAT039_RS05645	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RvVAT039_RS05655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RvVAT039_RS05660	COG0328	RNA-DNA hybrid ribonuclease activity
RvVAT039_RS05670	COG0803	Belongs to the bacterial solute-binding protein 9 family
RvVAT039_RS05685	COG0678	peroxiredoxin activity
RvVAT039_RS05685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RvVAT039_RS05695	COG1678	Uncharacterized ACR, COG1678
RvVAT039_RS05705	COG0640	Transcriptional regulator
RvVAT039_RS05710	COG5001	Diguanylate cyclase
RvVAT039_RS05715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RvVAT039_RS05720	COG0612	Peptidase, M16
RvVAT039_RS05735	COG1597	lipid kinase activity
RvVAT039_RS05740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RvVAT039_RS05755	COG2189	Belongs to the N(4) N(6)-methyltransferase family
RvVAT039_RS05785	COG1194	a g-specific adenine glycosylase
RvVAT039_RS05800	COG1196	nuclear chromosome segregation
RvVAT039_RS05815	COG2814	Major facilitator Superfamily
RvVAT039_RS05830	COG0574	Belongs to the PEP-utilizing enzyme family
RvVAT039_RS05830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RvVAT039_RS05865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_RS05885	COG0840	transmembrane signaling receptor activity
RvVAT039_RS05890	COG0175	sulfate reduction
RvVAT039_RS05895	COG0175	sulfate reduction
RvVAT039_RS05900	COG2895	sulfate adenylyltransferase (ATP) activity
RvVAT039_RS05920	COG1609	Transcriptional regulator
RvVAT039_RS05940	COG0693	protein deglycase activity
RvVAT039_RS05960	COG0038	chloride channel
RvVAT039_RS05965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_RS05990	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RvVAT039_RS05995	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS06000	COG0625	glutathione transferase activity
RvVAT039_RS06005	COG3119	arylsulfatase activity
RvVAT039_RS06010	COG1309	transcriptional regulator
RvVAT039_RS06015	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RvVAT039_RS06020	COG0604	alcohol dehydrogenase
RvVAT039_RS06020	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS06020	COG3321	synthase
RvVAT039_RS06050	COG1349	DNA-binding transcription factor activity
RvVAT039_RS06100	COG0477	Major facilitator Superfamily
RvVAT039_RS06110	COG0778	Nitroreductase
RvVAT039_RS06135	COG1388	LysM domain
RvVAT039_RS06135	COG1376	ErfK ybiS ycfS ynhG family protein
RvVAT039_RS06140	COG1376	ErfK ybiS ycfS ynhG family protein
RvVAT039_RS06145	COG1846	Transcriptional regulator
RvVAT039_RS06150	COG1764	response to oxidative stress
RvVAT039_RS06160	COG3920	Histidine kinase
RvVAT039_RS06165	COG4191	Histidine kinase
RvVAT039_RS06165	COG0784	Response regulator, receiver
RvVAT039_RS06170	COG3265	gluconokinase activity
RvVAT039_RS06180	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RvVAT039_RS06185	COG0840	transmembrane signaling receptor activity
RvVAT039_RS06190	COG0840	transmembrane signaling receptor activity
RvVAT039_RS06200	COG0433	COG0433 Predicted ATPase
RvVAT039_RS06215	COG0840	transmembrane signaling receptor activity
RvVAT039_RS06220	COG1968	undecaprenyl-diphosphatase activity
RvVAT039_RS06230	COG4214	carbohydrate transport
RvVAT039_RS06235	COG4213	ABC transporter substrate-binding protein
RvVAT039_RS06240	COG1940	carbohydrate kinase activity
RvVAT039_RS06240	COG1846	Transcriptional regulator
RvVAT039_RS06260	COG1120	ATPase activity
RvVAT039_RS06265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_RS06280	COG2226	methyltransferase
RvVAT039_RS06305	COG2010	Cytochrome c
RvVAT039_RS06325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RvVAT039_RS06330	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RvVAT039_RS06335	COG1733	regulation of RNA biosynthetic process
RvVAT039_RS06345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RvVAT039_RS06360	COG5002	protein histidine kinase activity
RvVAT039_RS06360	COG5001	Diguanylate cyclase
RvVAT039_RS06360	COG3447	MASE1 domain protein
RvVAT039_RS06365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_RS06405	COG2514	catechol 2,3-dioxygenase activity
RvVAT039_RS06420	COG3788	relative of glutathione S-transferase, MAPEG superfamily
RvVAT039_RS06425	COG1272	protein, Hemolysin III
RvVAT039_RS06430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RvVAT039_RS06450	COG4957	zinc ion binding
RvVAT039_RS06455	COG1320	monovalent cation:proton antiporter activity
RvVAT039_RS06460	COG2212	antiporter activity
RvVAT039_RS06465	COG1863	multisubunit Na H antiporter MnhE subunit
RvVAT039_RS06475	COG1006	Multisubunit Na H antiporter MnhC subunit
RvVAT039_RS06480	COG2111	Na H antiporter
RvVAT039_RS06490	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RvVAT039_RS06510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_RS06515	COG1136	(ABC) transporter
RvVAT039_RS06515	COG0577	efflux transmembrane transporter activity
RvVAT039_RS06525	COG1309	transcriptional regulator
RvVAT039_RS06530	COG2166	iron-sulfur cluster assembly
RvVAT039_RS06540	COG2205	protein histidine kinase activity
RvVAT039_RS06555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RvVAT039_RS06565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_RS06620	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RvVAT039_RS06625	COG2983	Belongs to the UPF0260 family
RvVAT039_RS06635	COG0789	Transcriptional regulator
RvVAT039_RS06660	COG4695	Portal protein
RvVAT039_RS06750	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS06755	COG2205	protein histidine kinase activity
RvVAT039_RS06760	COG4520	surface antigen
RvVAT039_RS06765	COG4235	cytochrome complex assembly
RvVAT039_RS06770	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
RvVAT039_RS06775	COG1138	Cytochrome C-type biogenesis protein
RvVAT039_RS06780	COG3088	subunit of a heme lyase
RvVAT039_RS06790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RvVAT039_RS06795	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS06800	COG2205	protein histidine kinase activity
RvVAT039_RS06805	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RvVAT039_RS06810	COG2202	Pas domain
RvVAT039_RS06810	COG2205	protein histidine kinase activity
RvVAT039_RS06815	COG0308	aminopeptidase N
RvVAT039_RS06820	COG0840	transmembrane signaling receptor activity
RvVAT039_RS06820	COG3290	protein histidine kinase activity
RvVAT039_RS06855	COG0443	Heat shock 70 kDa protein
RvVAT039_RS06870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_RS06885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_RS06890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RvVAT039_RS06895	COG2239	Acts as a magnesium transporter
RvVAT039_RS06900	COG2814	Major facilitator Superfamily
RvVAT039_RS06910	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_RS06915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS06920	COG0601	transmembrane transport
RvVAT039_RS06925	COG4166	transmembrane transport
RvVAT039_RS06930	COG0174	glutamine synthetase
RvVAT039_RS06945	COG1695	Transcriptional regulator
RvVAT039_RS06950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RvVAT039_RS06955	COG0463	Glycosyl transferase, family 2
RvVAT039_RS06965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RvVAT039_RS06975	COG0625	glutathione transferase activity
RvVAT039_RS06990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RvVAT039_RS07030	COG0741	lytic transglycosylase activity
RvVAT039_RS07035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RvVAT039_RS07040	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RvVAT039_RS07055	COG0840	transmembrane signaling receptor activity
RvVAT039_RS07065	COG1758	RNA polymerase activity
RvVAT039_RS07080	COG0681	Belongs to the peptidase S26 family
RvVAT039_RS07085	COG0571	ribonuclease III activity
RvVAT039_RS07090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RvVAT039_RS07095	COG3180	Ammonia monooxygenase
RvVAT039_RS07100	COG1381	Involved in DNA repair and RecF pathway recombination
RvVAT039_RS07115	COG1418	mRNA catabolic process
RvVAT039_RS07130	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
RvVAT039_RS07155	COG1051	belongs to the nudix hydrolase family
RvVAT039_RS07170	COG1183	phosphatidylcholine synthase activity
RvVAT039_RS07175	COG0688	phosphatidylethanolamine metabolic process
RvVAT039_RS07180	COG5265	(ABC) transporter
RvVAT039_RS07185	COG1652	LysM domain
RvVAT039_RS07185	COG2823	Periplasmic or secreted lipoprotein
RvVAT039_RS07200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RvVAT039_RS07235	COG0215	cysteine-tRNA ligase activity
RvVAT039_RS07240	COG5434	Belongs to the glycosyl hydrolase 28 family
RvVAT039_RS07245	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RvVAT039_RS07250	COG1088	dTDP-glucose 4,6-dehydratase activity
RvVAT039_RS07255	COG1091	dTDP-4-dehydrorhamnose reductase activity
RvVAT039_RS07260	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RvVAT039_RS07275	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS07280	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RvVAT039_RS07285	COG1286	toxin biosynthetic process
RvVAT039_RS07290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RvVAT039_RS07295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RvVAT039_RS07310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RvVAT039_RS07320	COG0765	amino acid transport
RvVAT039_RS07325	COG0765	amino acid transport
RvVAT039_RS07335	COG0305	Participates in initiation and elongation during chromosome replication
RvVAT039_RS07340	COG0359	binds to the 23S rRNA
RvVAT039_RS07350	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RvVAT039_RS07355	COG0360	Binds together with S18 to 16S ribosomal RNA
RvVAT039_RS07375	COG0667	Aldo Keto reductase
RvVAT039_RS07380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RvVAT039_RS07390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RvVAT039_RS07395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RvVAT039_RS07400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RvVAT039_RS07405	COG1561	YicC-like family, N-terminal region
RvVAT039_RS07410	COG0194	GDP metabolic process
RvVAT039_RS07415	COG0500	methyltransferase
RvVAT039_RS07420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RvVAT039_RS07425	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RvVAT039_RS07435	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RvVAT039_RS07450	COG0671	phosphoesterase, PA-phosphatase related
RvVAT039_RS07455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RvVAT039_RS07465	COG0840	transmembrane signaling receptor activity
RvVAT039_RS07470	COG0488	(ABC) transporter
RvVAT039_RS07480	COG0105	UTP biosynthetic process
RvVAT039_RS07485	COG0314	molybdopterin synthase activity
RvVAT039_RS07495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RvVAT039_RS07500	COG0322	excinuclease ABC activity
RvVAT039_RS07505	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS07515	COG0625	glutathione transferase activity
RvVAT039_RS07520	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RvVAT039_RS07525	COG0243	molybdopterin cofactor binding
RvVAT039_RS07535	COG3453	Protein conserved in bacteria
RvVAT039_RS07535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RvVAT039_RS07540	COG0640	Transcriptional regulator
RvVAT039_RS07550	COG2391	methyltransferase activity
RvVAT039_RS07555	COG0730	response to heat
RvVAT039_RS07560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RvVAT039_RS07565	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RvVAT039_RS07570	COG0628	permease
RvVAT039_RS07580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
RvVAT039_RS07585	COG0248	Ppx GppA phosphatase
RvVAT039_RS07590	COG1321	iron dependent repressor
RvVAT039_RS07595	COG1914	H( )-stimulated, divalent metal cation uptake system
RvVAT039_RS07615	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
RvVAT039_RS07630	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RvVAT039_RS07645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RvVAT039_RS07650	COG5001	Diguanylate cyclase
RvVAT039_RS07650	COG3300	MHYT domain
RvVAT039_RS07660	COG2203	Gaf domain
RvVAT039_RS07660	COG2199	diguanylate cyclase activity
RvVAT039_RS07660	COG2200	EAL domain
RvVAT039_RS07665	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
RvVAT039_RS07675	COG0113	porphobilinogen synthase activity
RvVAT039_RS07695	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RvVAT039_RS07700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RvVAT039_RS07705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RvVAT039_RS07705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RvVAT039_RS07730	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RvVAT039_RS07735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RvVAT039_RS07740	COG2814	Major facilitator Superfamily
RvVAT039_RS07745	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
RvVAT039_RS07765	COG0416	fatty acid biosynthetic process
RvVAT039_RS07770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RvVAT039_RS07775	COG0776	regulation of translation
RvVAT039_RS07800	COG0582	viral genome integration into host DNA
RvVAT039_RS07810	COG4104	PAAR repeat-containing protein
RvVAT039_RS07810	COG3209	COG3209 Rhs family protein
RvVAT039_RS07835	COG3209	COG3209 Rhs family protein
RvVAT039_RS07855	COG3501	Rhs element vgr protein
RvVAT039_RS07895	COG0587	DNA-directed DNA polymerase activity
RvVAT039_RS07955	COG1612	heme a metabolic process
RvVAT039_RS07960	COG3384	dioxygenase
RvVAT039_RS07970	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RvVAT039_RS07975	COG0010	Belongs to the arginase family
RvVAT039_RS07995	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RvVAT039_RS08000	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RvVAT039_RS08005	COG1832	CoA-binding protein
RvVAT039_RS08015	COG1832	CoA-binding protein
RvVAT039_RS08025	COG1408	metallophosphoesterase
RvVAT039_RS08035	COG2124	cytochrome p450
RvVAT039_RS08045	COG0740	serine-type endopeptidase activity
RvVAT039_RS08050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RvVAT039_RS08055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RvVAT039_RS08085	COG1024	Enoyl-CoA hydratase
RvVAT039_RS08105	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RvVAT039_RS08110	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RvVAT039_RS08115	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RvVAT039_RS08120	COG0649	NAD binding
RvVAT039_RS08130	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
RvVAT039_RS08135	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
RvVAT039_RS08150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RvVAT039_RS08155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RvVAT039_RS08165	COG0713	ATP synthesis coupled electron transport
RvVAT039_RS08180	COG1007	ATP synthesis coupled electron transport
RvVAT039_RS08195	COG0346	lactoylglutathione lyase activity
RvVAT039_RS08200	COG0251	oxidation-reduction process
RvVAT039_RS08215	COG0442	prolyl-tRNA aminoacylation
RvVAT039_RS08225	COG1136	(ABC) transporter
RvVAT039_RS08240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RvVAT039_RS08255	COG0784	Response regulator, receiver
RvVAT039_RS08265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RvVAT039_RS08270	COG0477	Major facilitator Superfamily
RvVAT039_RS08280	COG0557	exoribonuclease II activity
RvVAT039_RS08285	COG1754	DNA topoisomerase type I activity
RvVAT039_RS08285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RvVAT039_RS08295	COG0758	DNA mediated transformation
RvVAT039_RS08300	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RvVAT039_RS08310	COG0540	Belongs to the ATCase OTCase family
RvVAT039_RS08315	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_RS08335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RvVAT039_RS08340	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RvVAT039_RS08345	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RvVAT039_RS08350	COG0154	amidase activity
RvVAT039_RS08365	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RvVAT039_RS08370	COG3952	Lipid A Biosynthesis
RvVAT039_RS08370	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RvVAT039_RS08375	COG0463	Glycosyl transferase, family 2
RvVAT039_RS08380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RvVAT039_RS08400	COG4765	Protein conserved in bacteria
RvVAT039_RS08405	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
RvVAT039_RS08415	COG0511	ligase activity, forming carbon-carbon bonds
RvVAT039_RS08420	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RvVAT039_RS08425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RvVAT039_RS08430	COG0436	Aminotransferase
RvVAT039_RS08440	COG1530	ribonuclease E activity
RvVAT039_RS08450	COG0860	N-Acetylmuramoyl-L-alanine amidase
RvVAT039_RS08455	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RvVAT039_RS08465	COG0284	orotidine-5'-phosphate decarboxylase activity
RvVAT039_RS08475	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RvVAT039_RS08495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RvVAT039_RS08510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RvVAT039_RS08535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RvVAT039_RS08545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RvVAT039_RS08550	COG0081	regulation of translation
RvVAT039_RS08555	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RvVAT039_RS08560	COG0222	ribosome binding
RvVAT039_RS08565	COG0085	RNA polymerase activity
RvVAT039_RS08570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RvVAT039_RS08585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RvVAT039_RS08590	COG0049	tRNA binding
RvVAT039_RS08595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RvVAT039_RS08600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RvVAT039_RS08605	COG0051	transcription antitermination factor activity, RNA binding
RvVAT039_RS08610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RvVAT039_RS08615	COG0088	Forms part of the polypeptide exit tunnel
RvVAT039_RS08620	COG0089	rRNA binding
RvVAT039_RS08625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RvVAT039_RS08630	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RvVAT039_RS08635	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RvVAT039_RS08640	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RvVAT039_RS08645	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RvVAT039_RS08650	COG0255	Belongs to the universal ribosomal protein uL29 family
RvVAT039_RS08655	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RvVAT039_RS08660	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RvVAT039_RS08665	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RvVAT039_RS08670	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RvVAT039_RS08675	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RvVAT039_RS08680	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RvVAT039_RS08685	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RvVAT039_RS08690	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RvVAT039_RS08695	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RvVAT039_RS08700	COG1841	ribosomal large subunit assembly
RvVAT039_RS08705	COG0200	Binds to the 23S rRNA
RvVAT039_RS08710	COG0201	protein transport
RvVAT039_RS08715	COG0563	adenylate kinase activity
RvVAT039_RS08720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RvVAT039_RS08725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RvVAT039_RS08730	COG0202	RNA polymerase activity
RvVAT039_RS08735	COG0203	ribosomal protein L17
RvVAT039_RS08750	COG2897	thiosulfate sulfurtransferase activity
RvVAT039_RS08755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RvVAT039_RS08760	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RvVAT039_RS08765	COG0415	Belongs to the DNA photolyase family
RvVAT039_RS08775	COG0739	heme binding
RvVAT039_RS08780	COG2833	Protein of unknown function (DUF455)
RvVAT039_RS08785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RvVAT039_RS08810	COG0281	malic enzyme
RvVAT039_RS08810	COG0280	phosphate acetyltransferase
RvVAT039_RS08820	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RvVAT039_RS08825	COG1127	ABC transporter
RvVAT039_RS08835	COG3218	ABC-type transport auxiliary lipoprotein component
RvVAT039_RS08835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RvVAT039_RS08840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RvVAT039_RS08860	COG0047	phosphoribosylformylglycinamidine synthase activity
RvVAT039_RS08865	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RvVAT039_RS08870	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RvVAT039_RS08885	COG3706	GGDEF domain
RvVAT039_RS08895	COG0538	isocitrate dehydrogenase activity
RvVAT039_RS08900	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
RvVAT039_RS08905	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RvVAT039_RS08915	COG1253	flavin adenine dinucleotide binding
RvVAT039_RS08925	COG0657	acetylesterase activity
RvVAT039_RS08925	COG2755	lipolytic protein G-D-S-L family
RvVAT039_RS08930	COG2195	Cleaves the N-terminal amino acid of tripeptides
RvVAT039_RS08950	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RvVAT039_RS08955	COG2066	Belongs to the glutaminase family
RvVAT039_RS08965	COG0037	tRNA processing
RvVAT039_RS08970	COG0483	inositol monophosphate 1-phosphatase activity
RvVAT039_RS08975	COG0483	inositol monophosphate 1-phosphatase activity
RvVAT039_RS08980	COG2814	Major facilitator Superfamily
RvVAT039_RS08985	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RvVAT039_RS09000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RvVAT039_RS09005	COG0484	heat shock protein binding
RvVAT039_RS09015	COG0321	lipoyl(octanoyl) transferase activity
RvVAT039_RS09035	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS09060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RvVAT039_RS09080	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
RvVAT039_RS09085	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
RvVAT039_RS09115	COG0242	peptide deformylase activity
RvVAT039_RS09130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RvVAT039_RS09135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RvVAT039_RS09140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RvVAT039_RS09145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RvVAT039_RS09150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RvVAT039_RS09175	COG0823	Involved in the tonB-independent uptake of proteins
RvVAT039_RS09180	COG0778	Nitroreductase
RvVAT039_RS09185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RvVAT039_RS09190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RvVAT039_RS09195	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RvVAT039_RS09215	COG2202	Pas domain
RvVAT039_RS09215	COG2205	protein histidine kinase activity
RvVAT039_RS09225	COG1573	uracil-dna glycosylase
RvVAT039_RS09230	COG1522	sequence-specific DNA binding
RvVAT039_RS09235	COG2084	Dehydrogenase
RvVAT039_RS09240	COG2267	carboxylic ester hydrolase activity
RvVAT039_RS09250	COG5425	PFAM Usg family protein
RvVAT039_RS09275	COG1763	Mo-molybdopterin cofactor biosynthetic process
RvVAT039_RS09280	COG0746	molybdenum cofactor guanylyltransferase activity
RvVAT039_RS09290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RvVAT039_RS09300	COG3706	GGDEF domain
RvVAT039_RS09305	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RvVAT039_RS09305	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RvVAT039_RS09310	COG0114	fumarate hydratase activity
RvVAT039_RS09315	COG2989	Protein conserved in bacteria
RvVAT039_RS09320	COG0546	phosphoglycolate phosphatase activity
RvVAT039_RS09325	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
RvVAT039_RS09340	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
RvVAT039_RS09380	COG3706	GGDEF domain
RvVAT039_RS09380	COG4251	negative regulation of phosphorylation
RvVAT039_RS09380	COG2203	Gaf domain
RvVAT039_RS09380	COG5001	Diguanylate cyclase
RvVAT039_RS09385	COG0556	nucleotide-excision repair
RvVAT039_RS09405	COG3161	chorismate lyase activity
RvVAT039_RS09415	COG2877	3-deoxy-8-phosphooctulonate synthase activity
RvVAT039_RS09420	COG0148	phosphopyruvate hydratase activity
RvVAT039_RS09430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RvVAT039_RS09435	COG0022	dehydrogenase e1 component
RvVAT039_RS09435	COG0508	dehydrogenase complex catalyzes the overall conversion of
RvVAT039_RS09440	COG0508	dehydrogenase complex catalyzes the overall conversion of
RvVAT039_RS09460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RvVAT039_RS09470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RvVAT039_RS09475	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RvVAT039_RS09485	COG0477	Major facilitator Superfamily
RvVAT039_RS09490	COG2867	negative regulation of translational initiation
RvVAT039_RS09495	COG1546	Belongs to the CinA family
RvVAT039_RS09495	COG1058	Belongs to the CinA family
RvVAT039_RS09500	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RvVAT039_RS09500	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RvVAT039_RS09510	COG3852	Histidine kinase
RvVAT039_RS09515	COG2204	response regulator
RvVAT039_RS09520	COG5000	phosphorelay sensor kinase activity
RvVAT039_RS09525	COG2204	response regulator
RvVAT039_RS09530	COG1923	regulation of RNA biosynthetic process
RvVAT039_RS09535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RvVAT039_RS09545	COG3956	TIGRFAM MazG family protein
RvVAT039_RS09555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RvVAT039_RS09555	COG1648	precorrin-2 dehydrogenase activity
RvVAT039_RS09580	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS09590	COG1686	Belongs to the peptidase S11 family
RvVAT039_RS09595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RvVAT039_RS09605	COG0730	response to heat
RvVAT039_RS09610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RvVAT039_RS09615	COG0084	hydrolase, TatD family'
RvVAT039_RS09620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RvVAT039_RS09620	COG0321	lipoyl(octanoyl) transferase activity
RvVAT039_RS09635	COG0785	Cytochrome C biogenesis protein
RvVAT039_RS09640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RvVAT039_RS09645	COG1183	phosphatidylcholine synthase activity
RvVAT039_RS09655	COG1129	ABC transporter
RvVAT039_RS09680	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RvVAT039_RS09685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RvVAT039_RS09705	COG1177	transmembrane transport
RvVAT039_RS09710	COG4149	molybdate abc transporter
RvVAT039_RS09715	COG3842	ATPase activity
RvVAT039_RS09730	COG0523	cobalamin synthesis protein
RvVAT039_RS09740	COG1121	(ABC) transporter
RvVAT039_RS09745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RvVAT039_RS09750	COG0735	belongs to the Fur family
RvVAT039_RS09770	COG1686	Belongs to the peptidase S11 family
RvVAT039_RS09805	COG1752	Esterase of the alpha-beta hydrolase superfamily
RvVAT039_RS09810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RvVAT039_RS09815	COG0302	gtp cyclohydrolase
RvVAT039_RS09825	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RvVAT039_RS09835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RvVAT039_RS09850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RvVAT039_RS09855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RvVAT039_RS09900	COG0187	DNA topoisomerase II activity
RvVAT039_RS09915	COG0149	triose-phosphate isomerase activity
RvVAT039_RS09925	COG0504	CTP synthase activity
RvVAT039_RS09945	COG0633	Ferredoxin
RvVAT039_RS09955	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RvVAT039_RS09975	COG3768	UPF0283 membrane protein
RvVAT039_RS09980	COG3106	COG3106 Predicted ATPase
RvVAT039_RS10015	COG2080	2 iron, 2 sulfur cluster binding
RvVAT039_RS10020	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RvVAT039_RS10025	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RvVAT039_RS10030	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RvVAT039_RS10050	COG0343	queuine tRNA-ribosyltransferase activity
RvVAT039_RS10055	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RvVAT039_RS10070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RvVAT039_RS10085	COG2151	metal-sulfur cluster biosynthetic enzyme
RvVAT039_RS10090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RvVAT039_RS10095	COG0719	Fe-S assembly protein
RvVAT039_RS10100	COG0396	ATPase activity
RvVAT039_RS10110	COG0719	Fe-S assembly protein
RvVAT039_RS10120	COG2945	thiolester hydrolase activity
RvVAT039_RS10125	COG1280	lysine exporter protein (LysE YggA)
RvVAT039_RS10130	COG0513	Belongs to the DEAD box helicase family
RvVAT039_RS10155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RvVAT039_RS10180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RvVAT039_RS10195	COG0129	dihydroxy-acid dehydratase activity
RvVAT039_RS10200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RvVAT039_RS10205	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
RvVAT039_RS10220	COG3507	Belongs to the glycosyl hydrolase 43 family
RvVAT039_RS10225	COG0667	Aldo Keto reductase
RvVAT039_RS10245	COG3842	ATPase activity
RvVAT039_RS10250	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS10255	COG1175	transmembrane transport
RvVAT039_RS10260	COG1653	transport
RvVAT039_RS10275	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RvVAT039_RS10310	COG2095	MarC family integral membrane protein
RvVAT039_RS10320	COG0629	single-stranded DNA binding
RvVAT039_RS10325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RvVAT039_RS10335	COG0454	-acetyltransferase
RvVAT039_RS10340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RvVAT039_RS10340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RvVAT039_RS10345	COG0347	Belongs to the P(II) protein family
RvVAT039_RS10350	COG0174	glutamine synthetase
RvVAT039_RS10380	COG0697	spore germination
RvVAT039_RS10390	COG1280	lysine exporter protein (LysE YggA)
RvVAT039_RS10395	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RvVAT039_RS10405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RvVAT039_RS10435	COG1278	Cold shock
RvVAT039_RS10440	COG0346	lactoylglutathione lyase activity
RvVAT039_RS10465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RvVAT039_RS10475	COG0436	Aminotransferase
RvVAT039_RS10485	COG3243	poly(R)-hydroxyalkanoic acid synthase
RvVAT039_RS10490	COG1489	DNA binding
RvVAT039_RS10495	COG2855	membrane
RvVAT039_RS10500	COG0583	DNA-binding transcription factor activity
RvVAT039_RS10505	COG0024	Methionine aminopeptidase
RvVAT039_RS10510	COG2003	Belongs to the UPF0758 family
RvVAT039_RS10525	COG0477	Major facilitator Superfamily
RvVAT039_RS10540	COG0546	phosphoglycolate phosphatase activity
RvVAT039_RS10545	COG0564	pseudouridine synthase activity
RvVAT039_RS10550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RvVAT039_RS10570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RvVAT039_RS10575	COG0509	glycine decarboxylation via glycine cleavage system
RvVAT039_RS10580	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RvVAT039_RS10580	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RvVAT039_RS10605	COG0436	Aminotransferase
RvVAT039_RS10615	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RvVAT039_RS10620	COG0544	peptidyl-prolyl cis-trans isomerase activity
RvVAT039_RS10650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RvVAT039_RS10655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RvVAT039_RS10670	COG0252	asparaginase activity
RvVAT039_RS10680	COG0737	Belongs to the 5'-nucleotidase family
RvVAT039_RS10690	COG0463	Glycosyl transferase, family 2
RvVAT039_RS10695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RvVAT039_RS10710	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RvVAT039_RS10715	COG3665	Urea carboxylase-associated protein
RvVAT039_RS10725	COG4770	biotin carboxylase activity
RvVAT039_RS10745	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RvVAT039_RS10750	COG2153	protein acetylation
RvVAT039_RS10755	COG1671	Belongs to the UPF0178 family
RvVAT039_RS10765	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RvVAT039_RS10770	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RvVAT039_RS10780	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RvVAT039_RS10785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RvVAT039_RS10790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RvVAT039_RS10795	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RvVAT039_RS10800	COG0750	zinc metalloprotease
RvVAT039_RS10810	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RvVAT039_RS10815	COG0233	cytoplasmic translational termination
RvVAT039_RS10820	COG0528	UMP kinase activity
RvVAT039_RS10825	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RvVAT039_RS10830	COG0052	Belongs to the universal ribosomal protein uS2 family
RvVAT039_RS10855	COG0537	adenosine 5'-monophosphoramidase activity
RvVAT039_RS10875	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RvVAT039_RS10900	COG2267	carboxylic ester hydrolase activity
RvVAT039_RS10920	COG0626	cystathionine gamma-synthase activity
RvVAT039_RS10925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_RS10930	COG4597	amino acid ABC transporter
RvVAT039_RS10935	COG0765	amino acid transport
RvVAT039_RS10940	COG1126	abc transporter atp-binding protein
RvVAT039_RS10945	COG3920	Histidine kinase
RvVAT039_RS10945	COG2202	Pas domain
RvVAT039_RS10950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RvVAT039_RS10955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RvVAT039_RS10965	COG2313	pseudouridylate synthase activity
RvVAT039_RS10970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RvVAT039_RS10975	COG0658	competence protein
RvVAT039_RS10975	COG2333	competence protein COMEC
RvVAT039_RS10980	COG0372	Belongs to the citrate synthase family
RvVAT039_RS10990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RvVAT039_RS10995	COG0134	indole-3-glycerol-phosphate synthase activity
RvVAT039_RS11000	COG0315	cyclic pyranopterin monophosphate synthase activity
RvVAT039_RS11005	COG0303	'Molybdopterin
RvVAT039_RS11010	COG0671	phosphoesterase, PA-phosphatase related
RvVAT039_RS11015	COG1492	cobalamin metabolic process
RvVAT039_RS11025	COG4176	ABC-type proline glycine betaine transport system permease component
RvVAT039_RS11030	COG4175	Glycine betaine
RvVAT039_RS11030	COG0517	IMP dehydrogenase activity
RvVAT039_RS11075	COG0583	DNA-binding transcription factor activity
RvVAT039_RS11095	COG2852	Protein conserved in bacteria
RvVAT039_RS11105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RvVAT039_RS11115	COG0840	transmembrane signaling receptor activity
RvVAT039_RS11125	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
RvVAT039_RS11135	COG1058	Belongs to the CinA family
RvVAT039_RS11135	COG1546	Belongs to the CinA family
RvVAT039_RS11140	COG0840	transmembrane signaling receptor activity
RvVAT039_RS11140	COG2972	Histidine kinase
RvVAT039_RS11150	COG0835	chemotaxis
RvVAT039_RS11160	COG1760	l-serine dehydratase
RvVAT039_RS11185	COG2239	Acts as a magnesium transporter
RvVAT039_RS11215	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
RvVAT039_RS11220	COG2099	Precorrin-6x reductase
RvVAT039_RS11225	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RvVAT039_RS11240	COG2875	Belongs to the precorrin methyltransferase family
RvVAT039_RS11325	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
RvVAT039_RS11350	COG1862	Preprotein translocase
RvVAT039_RS11365	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RvVAT039_RS11370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RvVAT039_RS11375	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RvVAT039_RS11380	COG0805	protein transport
RvVAT039_RS11385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RvVAT039_RS11390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RvVAT039_RS11395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RvVAT039_RS11400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RvVAT039_RS11405	COG1472	Belongs to the glycosyl hydrolase 3 family
RvVAT039_RS11415	COG0018	arginyl-trna synthetase
RvVAT039_RS11420	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RvVAT039_RS11425	COG0316	Belongs to the HesB IscA family
RvVAT039_RS11445	COG0525	valine-tRNA ligase activity
RvVAT039_RS11460	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RvVAT039_RS11605	COG0305	Participates in initiation and elongation during chromosome replication
RvVAT039_RS11605	COG1372	Participates in initiation and elongation during chromosome replication
RvVAT039_RS11675	COG0842	Transport permease protein
RvVAT039_RS11680	COG1131	(ABC) transporter
RvVAT039_RS11690	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS11705	COG2226	methyltransferase
RvVAT039_RS11710	COG3264	Mechanosensitive ion channel
RvVAT039_RS11710	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
RvVAT039_RS11725	COG4558	Periplasmic binding protein
RvVAT039_RS11730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_RS11735	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RvVAT039_RS11750	COG0384	phenazine biosynthesis protein PhzF
RvVAT039_RS11770	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RvVAT039_RS11780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RvVAT039_RS11795	COG1522	sequence-specific DNA binding
RvVAT039_RS11800	COG1794	racemase activity, acting on amino acids and derivatives
RvVAT039_RS11805	COG1309	transcriptional regulator
RvVAT039_RS11810	COG2814	Major facilitator Superfamily
RvVAT039_RS11820	COG1733	regulation of RNA biosynthetic process
RvVAT039_RS11830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RvVAT039_RS11835	COG0789	Transcriptional regulator
RvVAT039_RS11840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RvVAT039_RS11845	COG0656	L-ascorbic acid biosynthetic process
RvVAT039_RS11860	COG0028	Belongs to the TPP enzyme family
RvVAT039_RS11875	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RvVAT039_RS11880	COG0560	Phosphoserine phosphatase
RvVAT039_RS11890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RvVAT039_RS11895	COG0330	HflC and HflK could
RvVAT039_RS11910	COG2259	Doxx family
RvVAT039_RS11915	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RvVAT039_RS11950	COG0277	FAD linked oxidase domain protein
RvVAT039_RS11955	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RvVAT039_RS11960	COG0581	inorganic phosphate transmembrane transporter activity
RvVAT039_RS11965	COG0573	inorganic phosphate transmembrane transporter activity
RvVAT039_RS11970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RvVAT039_RS12000	COG4993	Dehydrogenase
RvVAT039_RS12005	COG1335	isochorismatase
RvVAT039_RS12010	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RvVAT039_RS12015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RvVAT039_RS12055	COG2264	protein methyltransferase activity
RvVAT039_RS12060	COG1999	signal sequence binding
RvVAT039_RS12065	COG0840	transmembrane signaling receptor activity
RvVAT039_RS12070	COG0835	chemotaxis
RvVAT039_RS12085	COG2176	DNA-directed DNA polymerase activity
RvVAT039_RS12095	COG0456	acetyltransferase
RvVAT039_RS12125	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RvVAT039_RS12135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RvVAT039_RS12145	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RvVAT039_RS12155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RvVAT039_RS12160	COG0849	cell division
RvVAT039_RS12165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RvVAT039_RS12170	COG1181	Belongs to the D-alanine--D-alanine ligase family
RvVAT039_RS12180	COG0477	Major facilitator Superfamily
RvVAT039_RS12185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RvVAT039_RS12190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RvVAT039_RS12195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RvVAT039_RS12205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RvVAT039_RS12210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RvVAT039_RS12220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RvVAT039_RS12235	COG0275	rRNA processing
RvVAT039_RS12240	COG2001	Belongs to the MraZ family
RvVAT039_RS12260	COG3023	N-Acetylmuramoyl-L-alanine amidase
RvVAT039_RS12325	COG2226	methyltransferase
RvVAT039_RS12330	COG0840	transmembrane signaling receptor activity
RvVAT039_RS12350	COG2267	carboxylic ester hydrolase activity
RvVAT039_RS12360	COG0028	Belongs to the TPP enzyme family
RvVAT039_RS12370	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RvVAT039_RS12375	COG0251	oxidation-reduction process
RvVAT039_RS12390	COG1376	ErfK ybiS ycfS ynhG family protein
RvVAT039_RS12410	COG2182	Extracellular solute-binding protein
RvVAT039_RS12415	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RvVAT039_RS12420	COG4149	molybdate abc transporter
RvVAT039_RS12425	COG3842	ATPase activity
RvVAT039_RS12440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RvVAT039_RS12450	COG1396	sequence-specific DNA binding
RvVAT039_RS12495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RvVAT039_RS12500	COG0697	spore germination
RvVAT039_RS12510	COG2968	Membrane
RvVAT039_RS12540	COG0443	Heat shock 70 kDa protein
RvVAT039_RS12575	COG1278	Cold shock
RvVAT039_RS12610	COG0432	Pfam Uncharacterised protein family UPF0047
RvVAT039_RS12615	COG3706	GGDEF domain
RvVAT039_RS12615	COG4251	negative regulation of phosphorylation
RvVAT039_RS12615	COG5001	Diguanylate cyclase
RvVAT039_RS12615	COG2203	Gaf domain
RvVAT039_RS12625	COG0583	DNA-binding transcription factor activity
RvVAT039_RS12640	COG1473	amidohydrolase
RvVAT039_RS12660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RvVAT039_RS12670	COG1268	BioY protein
RvVAT039_RS12675	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RvVAT039_RS12685	COG0505	Belongs to the CarA family
RvVAT039_RS12690	COG0534	Mate efflux family protein
RvVAT039_RS12695	COG0583	DNA-binding transcription factor activity
RvVAT039_RS12700	COG0667	Aldo Keto reductase
RvVAT039_RS12705	COG2321	neutral zinc metallopeptidase
RvVAT039_RS12720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RvVAT039_RS12730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RvVAT039_RS12770	COG1522	sequence-specific DNA binding
RvVAT039_RS12775	COG0492	ferredoxin-NADP+ reductase activity
RvVAT039_RS12780	COG0583	DNA-binding transcription factor activity
RvVAT039_RS12785	COG0640	Transcriptional regulator
RvVAT039_RS12790	COG1902	pentaerythritol trinitrate reductase activity
RvVAT039_RS12810	COG0387	Pfam Sodium calcium exchanger
RvVAT039_RS12820	COG0436	Aminotransferase
RvVAT039_RS12835	COG1278	Cold shock
RvVAT039_RS12840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RvVAT039_RS12850	COG1846	Transcriptional regulator
RvVAT039_RS12855	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS12860	COG2205	protein histidine kinase activity
RvVAT039_RS12865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RvVAT039_RS12885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RvVAT039_RS12900	COG0006	proline dipeptidase activity
RvVAT039_RS12910	COG1064	alcohol dehydrogenase
RvVAT039_RS12920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RvVAT039_RS12935	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS12945	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RvVAT039_RS12960	COG0193	aminoacyl-tRNA hydrolase activity
RvVAT039_RS12970	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RvVAT039_RS12975	COG0012	GTP binding
RvVAT039_RS12995	COG0386	Belongs to the glutathione peroxidase family
RvVAT039_RS13005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RvVAT039_RS13010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RvVAT039_RS13010	COG2857	Cytochrome c1
RvVAT039_RS13040	COG1132	(ABC) transporter
RvVAT039_RS13050	COG1132	(ABC) transporter
RvVAT039_RS13055	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RvVAT039_RS13065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_RS13075	COG0408	coproporphyrinogen oxidase activity
RvVAT039_RS13090	COG0617	tRNA 3'-terminal CCA addition
RvVAT039_RS13105	COG0714	Associated with various cellular activities
RvVAT039_RS13125	COG0454	-acetyltransferase
RvVAT039_RS13150	COG0435	Glutathione S-transferase
RvVAT039_RS13165	COG0740	serine-type endopeptidase activity
RvVAT039_RS13170	COG3135	benzoate transporter
RvVAT039_RS13175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RvVAT039_RS13185	COG4115	mRNA cleavage
RvVAT039_RS13205	COG3501	Rhs element vgr protein
RvVAT039_RS13230	COG0512	Glutamine amidotransferase of anthranilate synthase
RvVAT039_RS13230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RvVAT039_RS13240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RvVAT039_RS13245	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RvVAT039_RS13255	COG3416	Protein conserved in bacteria
RvVAT039_RS13265	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RvVAT039_RS13280	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RvVAT039_RS13285	COG2197	response regulator
RvVAT039_RS13300	COG1435	thymidine kinase activity
RvVAT039_RS13315	COG4175	Glycine betaine
RvVAT039_RS13355	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RvVAT039_RS13370	COG0366	Alpha amylase catalytic
RvVAT039_RS13380	COG1160	GTP binding
RvVAT039_RS13400	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
RvVAT039_RS13405	COG0477	Major facilitator Superfamily
RvVAT039_RS13415	COG0024	Methionine aminopeptidase
RvVAT039_RS13420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_RS13425	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RvVAT039_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS13440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RvVAT039_RS13450	COG0457	Tetratricopeptide repeat
RvVAT039_RS13455	COG0583	DNA-binding transcription factor activity
RvVAT039_RS13465	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_RS13475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_RS13485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_RS13535	COG2351	hydroxyisourate hydrolase activity
RvVAT039_RS13540	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
RvVAT039_RS13545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RvVAT039_RS13550	COG0174	glutamine synthetase
RvVAT039_RS13560	COG3648	Uricase
RvVAT039_RS13560	COG3195	allantoin biosynthetic process
RvVAT039_RS13565	COG1064	alcohol dehydrogenase
RvVAT039_RS13585	COG3706	GGDEF domain
RvVAT039_RS13600	COG2022	thiamine diphosphate biosynthetic process
RvVAT039_RS13600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_RS13605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_RS13605	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
RvVAT039_RS13610	COG2205	protein histidine kinase activity
RvVAT039_RS13610	COG5002	protein histidine kinase activity
RvVAT039_RS13610	COG0784	Response regulator, receiver
RvVAT039_RS13620	COG0513	Belongs to the DEAD box helicase family
RvVAT039_RS13635	COG1733	regulation of RNA biosynthetic process
RvVAT039_RS13650	COG0714	Associated with various cellular activities
RvVAT039_RS13655	COG2425	protein containing a von Willebrand factor type A (vWA) domain
RvVAT039_RS13665	COG3552	Protein containing von Willebrand factor type A (VWA) domain
RvVAT039_RS13670	COG4715	Zinc finger, swim domain protein
RvVAT039_RS13680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RvVAT039_RS13695	COG1982	Orn Lys Arg decarboxylase major
RvVAT039_RS13755	COG3501	Rhs element vgr protein
RvVAT039_RS13805	COG2308	Evidence 4 Homologs of previously reported genes of
RvVAT039_RS13820	COG2346	COG2346, Truncated hemoglobins
RvVAT039_RS13840	COG0493	'glutamate synthase
RvVAT039_RS13860	COG1309	transcriptional regulator
RvVAT039_RS13885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_RS13890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_RS13895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_RS13915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RvVAT039_RS13920	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RvVAT039_RS13925	COG0830	nickel cation binding
RvVAT039_RS13930	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
RvVAT039_RS13935	COG5001	Diguanylate cyclase
RvVAT039_RS13935	COG5002	protein histidine kinase activity
RvVAT039_RS13960	COG0804	urea catabolic process
RvVAT039_RS13965	COG1442	glycosyl transferase family 8
RvVAT039_RS13970	COG3755	Protein conserved in bacteria
RvVAT039_RS13975	COG0832	Belongs to the urease beta subunit family
RvVAT039_RS13980	COG3813	Protein conserved in bacteria
RvVAT039_RS13985	COG0831	urea catabolic process
RvVAT039_RS13990	COG0829	nickel cation binding
RvVAT039_RS14035	COG4251	negative regulation of phosphorylation
RvVAT039_RS14045	COG0784	Response regulator, receiver
RvVAT039_RS14045	COG2205	protein histidine kinase activity
RvVAT039_RS14070	COG2336	PFAM SpoVT AbrB
RvVAT039_RS14080	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
RvVAT039_RS14085	COG2894	cell division
RvVAT039_RS14090	COG0850	regulation of cytokinetic process
RvVAT039_RS14140	COG2814	Major facilitator Superfamily
RvVAT039_RS14150	COG1218	3'(2'),5'-bisphosphate nucleotidase
RvVAT039_RS14205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RvVAT039_RS14215	COG0564	pseudouridine synthase activity
RvVAT039_RS14220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_RS14220	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
RvVAT039_RS14225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RvVAT039_RS14235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RvVAT039_RS14250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RvVAT039_RS14260	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RvVAT039_RS14280	COG1116	anion transmembrane transporter activity
RvVAT039_RS14290	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_RS14300	COG2249	NAD(P)H dehydrogenase (quinone) activity
RvVAT039_RS14325	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RvVAT039_RS14360	COG1175	transmembrane transport
RvVAT039_RS14385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RvVAT039_RS14395	COG0482	sulfurtransferase activity
RvVAT039_RS14540	COG5005	Phage virion morphogenesis
RvVAT039_RS14600	COG4396	Host-nuclease inhibitor protein Gam
RvVAT039_RS14655	COG4774	siderophore transport
RvVAT039_RS14675	COG1120	ATPase activity
RvVAT039_RS14685	COG4774	siderophore transport
RvVAT039_RS14710	COG1294	oxidase, subunit
RvVAT039_RS14715	COG1271	oxidase subunit
RvVAT039_RS14725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RvVAT039_RS14750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_RS14755	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RvVAT039_RS14760	COG0632	four-way junction helicase activity
RvVAT039_RS14765	COG2002	toxin-antitoxin pair type II binding
RvVAT039_RS14775	COG2255	four-way junction helicase activity
RvVAT039_RS14780	COG1408	metallophosphoesterase
RvVAT039_RS14785	COG0494	nUDIX hydrolase
RvVAT039_RS14800	COG0824	Thioesterase
RvVAT039_RS14820	COG0823	Involved in the tonB-independent uptake of proteins
RvVAT039_RS14825	COG2885	chlorophyll binding
RvVAT039_RS14835	COG0037	tRNA processing
RvVAT039_RS14840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RvVAT039_RS14850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RvVAT039_RS14855	COG0217	transcriptional regulatory protein
RvVAT039_RS14930	COG0840	transmembrane signaling receptor activity
RvVAT039_RS14930	COG2972	Histidine kinase
RvVAT039_RS14935	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RvVAT039_RS14940	COG1692	metallophosphoesterase
RvVAT039_RS14945	COG0126	phosphoglycerate kinase activity
RvVAT039_RS14950	COG3588	fructose-bisphosphate aldolase
RvVAT039_RS14955	COG0384	phenazine biosynthesis protein PhzF
RvVAT039_RS14990	COG0254	rRNA binding
RvVAT039_RS14995	COG1132	(ABC) transporter
RvVAT039_RS15015	COG0483	inositol monophosphate 1-phosphatase activity
RvVAT039_RS15025	COG0352	thiamine-phosphate diphosphorylase activity
RvVAT039_RS15035	COG0640	Transcriptional regulator
RvVAT039_RS15050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RvVAT039_RS15055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RvVAT039_RS15060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RvVAT039_RS15065	COG0457	Tetratricopeptide repeat
RvVAT039_RS15070	COG0596	Alpha beta hydrolase
RvVAT039_RS15075	COG0469	pyruvate kinase activity
RvVAT039_RS15095	COG3750	Belongs to the UPF0335 family
RvVAT039_RS15115	COG0512	Glutamine amidotransferase of anthranilate synthase
RvVAT039_RS15115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RvVAT039_RS15120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_RS15130	COG5310	Homospermidine synthase
RvVAT039_RS15140	COG0737	Belongs to the 5'-nucleotidase family
RvVAT039_RS15145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RvVAT039_RS15155	COG0840	transmembrane signaling receptor activity
RvVAT039_RS15165	COG0602	queuosine metabolic process
RvVAT039_RS15170	COG0720	synthase
RvVAT039_RS15175	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RvVAT039_RS15180	COG0330	HflC and HflK could
RvVAT039_RS15190	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RvVAT039_RS15190	COG0517	IMP dehydrogenase activity
RvVAT039_RS15200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RvVAT039_RS15205	COG2951	lytic endotransglycosylase activity
RvVAT039_RS15215	COG0840	transmembrane signaling receptor activity
RvVAT039_RS15230	COG1487	ribonuclease activity
RvVAT039_RS15240	COG0070	glutamate synthase
RvVAT039_RS15240	COG0069	glutamate synthase activity
RvVAT039_RS15240	COG0067	glutamate synthase
RvVAT039_RS15250	COG0071	Belongs to the small heat shock protein (HSP20) family
RvVAT039_RS15285	COG0668	transmembrane transport
RvVAT039_RS15290	COG0662	Cupin 2, conserved barrel domain protein
RvVAT039_RS15290	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
RvVAT039_RS15300	COG2307	Protein conserved in bacteria
RvVAT039_RS15300	COG2308	Evidence 4 Homologs of previously reported genes of
RvVAT039_RS15320	COG0058	SHG alpha-glucan phosphorylase activity
RvVAT039_RS15325	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RvVAT039_RS15330	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RvVAT039_RS15335	COG0297	glycogen (starch) synthase activity
RvVAT039_RS15340	COG0033	Phosphoglucomutase
RvVAT039_RS15365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RvVAT039_RS15385	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RvVAT039_RS15390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_RS15400	COG0446	pyridine nucleotide-disulphide oxidoreductase
RvVAT039_RS15400	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RvVAT039_RS15415	COG1733	regulation of RNA biosynthetic process
RvVAT039_RS15430	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RvVAT039_RS15435	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RvVAT039_RS15440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RvVAT039_RS15445	COG1609	Transcriptional regulator
RvVAT039_RS15450	COG1846	Transcriptional regulator
RvVAT039_RS15460	COG0523	cobalamin synthesis protein
RvVAT039_RS15475	COG3047	cAMP biosynthetic process
RvVAT039_RS15500	COG0583	DNA-binding transcription factor activity
RvVAT039_RS15530	COG0800	Aldolase
RvVAT039_RS15535	COG2954	triphosphatase activity
RvVAT039_RS15545	COG2378	regulation of single-species biofilm formation
RvVAT039_RS15560	COG2202	Pas domain
RvVAT039_RS15560	COG2200	EAL domain
RvVAT039_RS15560	COG2199	diguanylate cyclase activity
RvVAT039_RS15580	COG0673	inositol 2-dehydrogenase activity
RvVAT039_RS15590	COG2115	Belongs to the xylose isomerase family
RvVAT039_RS15595	COG1070	Carbohydrate kinase
RvVAT039_RS15600	COG1609	Transcriptional regulator
RvVAT039_RS15615	COG1309	transcriptional regulator
RvVAT039_RS15620	COG1253	flavin adenine dinucleotide binding
RvVAT039_RS15640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RvVAT039_RS15665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RvVAT039_RS15685	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RvVAT039_RS15690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RvVAT039_RS15695	COG0471	metal ion transport
RvVAT039_RS15695	COG3273	potassium ion transport
RvVAT039_RS15710	COG2274	protein secretion by the type I secretion system
RvVAT039_RS15745	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_RS15750	COG1473	amidohydrolase
RvVAT039_RS15765	COG0601	transmembrane transport
RvVAT039_RS15770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS15775	COG0842	Transport permease protein
RvVAT039_RS15780	COG0842	Transport permease protein
RvVAT039_RS15780	COG1129	ABC transporter
RvVAT039_RS15785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_RS15795	COG3454	Phosphonate metabolism
RvVAT039_RS15810	COG0444	Belongs to the ABC transporter superfamily
RvVAT039_RS15820	COG0601	transmembrane transport
RvVAT039_RS15835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RvVAT039_RS15840	COG1802	Transcriptional regulator
RvVAT039_RS15845	COG1904	glucuronate isomerase
RvVAT039_RS15850	COG1917	Cupin 2, conserved barrel domain protein
RvVAT039_RS15860	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS15865	COG0246	Mannitol dehydrogenase
RvVAT039_RS15870	COG1312	Catalyzes the dehydration of D-mannonate
RvVAT039_RS15875	COG2721	sulfolactate sulfo-lyase activity
RvVAT039_RS15885	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RvVAT039_RS15900	COG4213	ABC transporter substrate-binding protein
RvVAT039_RS15905	COG1129	ABC transporter
RvVAT039_RS15910	COG4214	carbohydrate transport
RvVAT039_RS15920	COG0129	dihydroxy-acid dehydratase activity
RvVAT039_RS15935	COG3734	2-keto-3-deoxy-galactonokinase
RvVAT039_RS15940	COG0800	Aldolase
RvVAT039_RS15945	COG2832	Protein of unknown function (DUF454)
RvVAT039_RS15950	COG0697	spore germination
RvVAT039_RS15955	COG2186	Transcriptional regulator
RvVAT039_RS15960	COG2807	transmembrane transport
RvVAT039_RS15965	COG2373	Large extracellular alpha-helical protein
RvVAT039_RS15970	COG4953	penicillin-binding protein 1C
RvVAT039_RS15975	COG0840	transmembrane signaling receptor activity
RvVAT039_RS15975	COG2972	Histidine kinase
RvVAT039_RS15980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RvVAT039_RS15985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RvVAT039_RS15990	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_RS16000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS16005	COG0601	transmembrane transport
RvVAT039_RS16010	COG0747	negative chemotaxis
RvVAT039_RS16030	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_RS16060	COG0419	ATPase involved in DNA repair
RvVAT039_RS16065	COG0840	transmembrane signaling receptor activity
RvVAT039_RS16105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RvVAT039_RS16115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_RS16120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RvVAT039_RS16130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RvVAT039_RS16145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RvVAT039_RS16155	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RvVAT039_RS16185	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_RS16200	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RvVAT039_RS16210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_RS16225	COG1793	dna ligase
RvVAT039_RS16245	COG0783	Belongs to the Dps family
RvVAT039_RS16255	COG0784	Response regulator, receiver
RvVAT039_RS16295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RvVAT039_RS16310	COG0848	biopolymer transport protein
RvVAT039_RS16320	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RvVAT039_RS16335	COG0010	Belongs to the arginase family
RvVAT039_RS16355	COG1940	carbohydrate kinase activity
RvVAT039_RS16375	COG1072	(Pantothenic acid kinase))
RvVAT039_RS16380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_RS16385	COG0765	amino acid transport
RvVAT039_RS16390	COG0765	amino acid transport
RvVAT039_RS16395	COG4598	ABC transporter
RvVAT039_RS16410	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_RS16415	COG1228	amidohydrolase
RvVAT039_RS16420	COG2986	histidine ammonia-lyase
RvVAT039_RS16430	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
RvVAT039_RS16470	COG0583	DNA-binding transcription factor activity
RvVAT039_RS16475	COG0346	lactoylglutathione lyase activity
RvVAT039_RS16500	COG0765	amino acid transport
RvVAT039_RS16505	COG0765	amino acid transport
RvVAT039_RS16510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_RS16515	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RvVAT039_RS16520	COG0583	DNA-binding transcription factor activity
RvVAT039_RS16530	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS16535	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RvVAT039_RS16535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RvVAT039_RS16540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RvVAT039_RS16550	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_RS16555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS16560	COG0601	transmembrane transport
RvVAT039_RS16565	COG0747	negative chemotaxis
RvVAT039_RS16570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RvVAT039_RS16575	COG2186	Transcriptional regulator
RvVAT039_RS16585	COG0640	Transcriptional regulator
RvVAT039_RS16595	COG3842	ATPase activity
RvVAT039_RS16600	COG1175	transmembrane transport
RvVAT039_RS16605	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS16615	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RvVAT039_RS16625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_RS16630	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS16635	COG2084	Dehydrogenase
RvVAT039_RS16645	COG3386	PFAM SMP-30 Gluconolaconase
RvVAT039_RS16655	COG2771	luxR family
RvVAT039_RS16665	COG0626	cystathionine gamma-synthase activity
RvVAT039_RS16680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RvVAT039_RS16715	COG1175	transmembrane transport
RvVAT039_RS16720	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS16745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RvVAT039_RS16745	COG0446	pyridine nucleotide-disulphide oxidoreductase
RvVAT039_RS16750	COG4311	Sarcosine oxidase, delta subunit
RvVAT039_RS16755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_RS16760	COG4977	sequence-specific DNA binding
RvVAT039_RS16770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RvVAT039_RS16775	COG2218	PFAM glutamate synthase alpha subunit domain protein
RvVAT039_RS16780	COG0069	glutamate synthase activity
RvVAT039_RS16795	COG1304	FMN binding
RvVAT039_RS16810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RvVAT039_RS16825	COG1175	transmembrane transport
RvVAT039_RS16830	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS16850	COG0412	Dienelactone hydrolase
RvVAT039_RS16860	COG0583	DNA-binding transcription factor activity
RvVAT039_RS16870	COG0583	DNA-binding transcription factor activity
RvVAT039_RS16895	COG0306	phosphate transporter
RvVAT039_RS16910	COG0277	FAD linked oxidase domain protein
RvVAT039_RS16915	COG0277	FAD linked oxidase domain protein
RvVAT039_RS16920	COG0247	lactate metabolic process
RvVAT039_RS16930	COG0625	glutathione transferase activity
RvVAT039_RS16940	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RvVAT039_RS16945	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RvVAT039_RS16955	COG2852	Protein conserved in bacteria
RvVAT039_RS16960	COG0124	histidyl-tRNA synthetase
RvVAT039_RS16990	COG2818	Glycosylase
RvVAT039_RS16995	COG1376	ErfK ybiS ycfS ynhG family protein
RvVAT039_RS16995	COG1388	LysM domain
RvVAT039_RS17000	COG1376	ErfK ybiS ycfS ynhG family protein
RvVAT039_RS17015	COG2137	regulation of response to DNA damage stimulus
RvVAT039_RS17020	COG2130	NADP-dependent
RvVAT039_RS17035	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RvVAT039_RS17050	COG0196	riboflavin kinase activity
RvVAT039_RS17060	COG2059	Chromate
RvVAT039_RS17065	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RvVAT039_RS17070	COG0459	protein refolding
RvVAT039_RS17090	COG3842	ATPase activity
RvVAT039_RS17100	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_RS17105	COG1177	transmembrane transport
RvVAT039_RS17110	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RvVAT039_RS17115	COG0019	diaminopimelate decarboxylase activity
RvVAT039_RS17125	COG4770	biotin carboxylase activity
RvVAT039_RS17130	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RvVAT039_RS17135	COG4336	lyase activity
RvVAT039_RS17140	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RvVAT039_RS17145	COG1914	H( )-stimulated, divalent metal cation uptake system
RvVAT039_RS17150	COG1802	Transcriptional regulator
RvVAT039_RS17155	COG1522	sequence-specific DNA binding
RvVAT039_RS17160	COG2515	1-aminocyclopropane-1-carboxylate deaminase
RvVAT039_RS17185	COG0583	DNA-binding transcription factor activity
RvVAT039_RS17190	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RvVAT039_RS17195	COG0511	ligase activity, forming carbon-carbon bonds
RvVAT039_RS17200	COG0439	Biotin carboxylase
RvVAT039_RS17210	COG1984	allophanate hydrolase subunit 2
RvVAT039_RS17220	COG3842	ATPase activity
RvVAT039_RS17225	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_RS17235	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS17240	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS17250	COG3842	ATPase activity
RvVAT039_RS17255	COG0726	polysaccharide deacetylase
RvVAT039_RS17265	COG0523	cobalamin synthesis protein
RvVAT039_RS17280	COG1522	sequence-specific DNA binding
RvVAT039_RS17285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_RS17290	COG0659	secondary active sulfate transmembrane transporter activity
RvVAT039_RS17300	COG0243	molybdopterin cofactor binding
RvVAT039_RS17310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RvVAT039_RS17315	COG1116	anion transmembrane transporter activity
RvVAT039_RS17320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_RS17325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_RS17330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_RS17335	COG3707	response regulator
RvVAT039_RS17355	COG0583	DNA-binding transcription factor activity
RvVAT039_RS17360	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_RS17365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RvVAT039_RS17380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_RS17395	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RvVAT039_RS17410	COG2022	thiamine diphosphate biosynthetic process
RvVAT039_RS17570	COG0640	Transcriptional regulator
RvVAT039_RS17580	COG0798	PFAM Bile acid sodium symporter
RvVAT039_RS17590	COG0431	NADPH-dependent FMN reductase
RvVAT039_RS17630	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS17635	COG2205	protein histidine kinase activity
RvVAT039_RS17640	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
RvVAT039_RS17650	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RvVAT039_RS17675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_RS17680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RvVAT039_RS17685	COG1522	sequence-specific DNA binding
RvVAT039_RS17700	COG2267	carboxylic ester hydrolase activity
RvVAT039_RS17710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_RS17715	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS17730	COG1177	transmembrane transport
RvVAT039_RS17735	COG3842	ATPase activity
RvVAT039_RS17740	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS17745	COG1879	ABC-type sugar transport system periplasmic component
RvVAT039_RS17750	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS17755	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS17760	COG1129	ABC transporter
RvVAT039_RS17770	COG4154	Belongs to the RbsD FucU family
RvVAT039_RS17780	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS17785	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS17790	COG1129	ABC transporter
RvVAT039_RS17810	COG2721	sulfolactate sulfo-lyase activity
RvVAT039_RS17820	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS17830	COG2205	protein histidine kinase activity
RvVAT039_RS17835	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS17870	COG0183	Belongs to the thiolase family
RvVAT039_RS17875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RvVAT039_RS17885	COG1414	Transcriptional regulator
RvVAT039_RS17900	COG0583	DNA-binding transcription factor activity
RvVAT039_RS17905	COG2267	carboxylic ester hydrolase activity
RvVAT039_RS17910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RvVAT039_RS17915	COG3485	protocatechuate 3,4-dioxygenase
RvVAT039_RS17920	COG3485	protocatechuate 3,4-dioxygenase
RvVAT039_RS17925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RvVAT039_RS17930	COG0604	alcohol dehydrogenase
RvVAT039_RS17940	COG3842	ATPase activity
RvVAT039_RS17955	COG0668	transmembrane transport
RvVAT039_RS17975	COG5265	(ABC) transporter
RvVAT039_RS17980	COG2205	protein histidine kinase activity
RvVAT039_RS17985	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS18000	COG0582	viral genome integration into host DNA
RvVAT039_RS18185	COG3750	Belongs to the UPF0335 family
RvVAT039_RS18225	COG1396	sequence-specific DNA binding
RvVAT039_RS18355	COG3346	SURF1 family
RvVAT039_RS18360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RvVAT039_RS18365	COG1845	cytochrome c oxidase, subunit III
RvVAT039_RS18370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RvVAT039_RS18380	COG1595	DNA-templated transcription, initiation
RvVAT039_RS18390	COG0670	Belongs to the BI1 family
RvVAT039_RS18405	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RvVAT039_RS18405	COG2273	Hydrolase Family 16
RvVAT039_RS18410	COG1301	dicarboxylic acid transport
RvVAT039_RS18415	COG4191	Histidine kinase
RvVAT039_RS18420	COG2204	response regulator
RvVAT039_RS18425	COG1309	transcriptional regulator
RvVAT039_RS18440	COG1940	carbohydrate kinase activity
RvVAT039_RS18445	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RvVAT039_RS18450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RvVAT039_RS18455	COG2188	Transcriptional regulator
RvVAT039_RS18470	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS18480	COG3842	ATPase activity
RvVAT039_RS18505	COG1737	Transcriptional regulator
RvVAT039_RS18505	COG0837	glucose binding
RvVAT039_RS18510	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS18525	COG2814	Major facilitator Superfamily
RvVAT039_RS18530	COG3142	Participates in the control of copper homeostasis
RvVAT039_RS18550	COG0642	Histidine kinase
RvVAT039_RS18555	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS18570	COG4952	isomerase
RvVAT039_RS18575	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS18575	COG3347	Dehydrogenase
RvVAT039_RS18590	COG1129	ABC transporter
RvVAT039_RS18595	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS18600	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS18605	COG3254	rhamnose metabolic process
RvVAT039_RS18615	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_RS18620	COG5001	Diguanylate cyclase
RvVAT039_RS18630	COG1178	ABC-type Fe3 transport system permease component
RvVAT039_RS18635	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_RS18645	COG3842	ATPase activity
RvVAT039_RS18665	COG2094	Belongs to the DNA glycosylase MPG family
RvVAT039_RS18670	COG4181	ATPase activity
RvVAT039_RS18685	COG4303	Ethanolamine ammonia lyase large subunit
RvVAT039_RS18690	COG4302	ethanolamine ammonia-lyase activity
RvVAT039_RS18695	COG1192	Involved in chromosome partitioning
RvVAT039_RS18700	COG1475	DNA binding
RvVAT039_RS18705	COG1414	Transcriptional regulator
RvVAT039_RS18710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RvVAT039_RS18715	COG0392	lysyltransferase activity
RvVAT039_RS18725	COG3257	ureidoglycine aminohydrolase activity
RvVAT039_RS18745	COG1522	sequence-specific DNA binding
RvVAT039_RS18770	COG2040	homocysteine
RvVAT039_RS18775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_RS18785	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RvVAT039_RS18790	COG1473	amidohydrolase
RvVAT039_RS18800	COG0297	glycogen (starch) synthase activity
RvVAT039_RS18825	COG1063	alcohol dehydrogenase
RvVAT039_RS18830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RvVAT039_RS18835	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS18840	COG3265	gluconokinase activity
RvVAT039_RS18845	COG2084	Dehydrogenase
RvVAT039_RS18855	COG1609	Transcriptional regulator
RvVAT039_RS18870	COG1129	ABC transporter
RvVAT039_RS18885	COG1879	ABC-type sugar transport system periplasmic component
RvVAT039_RS18890	COG1129	ABC transporter
RvVAT039_RS18895	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS18900	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS18905	COG2186	Transcriptional regulator
RvVAT039_RS18910	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS18915	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS18925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RvVAT039_RS18935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_RS18940	COG1116	anion transmembrane transporter activity
RvVAT039_RS18960	COG0778	Nitroreductase
RvVAT039_RS18970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RvVAT039_RS18975	COG0659	secondary active sulfate transmembrane transporter activity
RvVAT039_RS18980	COG0589	response to stress
RvVAT039_RS19035	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_RS19045	COG1802	Transcriptional regulator
RvVAT039_RS19055	COG2723	6-phospho-beta-galactosidase activity
RvVAT039_RS19060	COG0601	transmembrane transport
RvVAT039_RS19070	COG3964	amidohydrolase
RvVAT039_RS19085	COG1921	L-seryl-tRNASec selenium transferase activity
RvVAT039_RS19090	COG5001	Diguanylate cyclase
RvVAT039_RS19090	COG2203	Gaf domain
RvVAT039_RS19090	COG4251	negative regulation of phosphorylation
RvVAT039_RS19090	COG3706	GGDEF domain
RvVAT039_RS19110	COG2080	2 iron, 2 sulfur cluster binding
RvVAT039_RS19115	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RvVAT039_RS19120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RvVAT039_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS19150	COG0656	L-ascorbic acid biosynthetic process
RvVAT039_RS19155	COG0583	DNA-binding transcription factor activity
RvVAT039_RS19160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RvVAT039_RS19165	COG1486	melibiose metabolic process
RvVAT039_RS19170	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_RS19175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS19180	COG0601	transmembrane transport
RvVAT039_RS19185	COG0747	negative chemotaxis
RvVAT039_RS19190	COG1486	melibiose metabolic process
RvVAT039_RS19195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RvVAT039_RS19195	COG2207	Transcriptional regulator
RvVAT039_RS19210	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS19225	COG1063	alcohol dehydrogenase
RvVAT039_RS19230	COG4948	Mandelate Racemase Muconate Lactonizing
RvVAT039_RS19250	COG4214	carbohydrate transport
RvVAT039_RS19255	COG1129	ABC transporter
RvVAT039_RS19270	COG1175	transmembrane transport
RvVAT039_RS19275	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS19295	COG1609	Transcriptional regulator
RvVAT039_RS19310	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS19325	COG2972	Histidine kinase
RvVAT039_RS19325	COG0840	transmembrane signaling receptor activity
RvVAT039_RS19350	COG0667	Aldo Keto reductase
RvVAT039_RS19365	COG1129	ABC transporter
RvVAT039_RS19370	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS19375	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS19380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_RS19395	COG0765	amino acid transport
RvVAT039_RS19400	COG1126	abc transporter atp-binding protein
RvVAT039_RS19405	COG2079	MmgE PrpD family protein
RvVAT039_RS19410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_RS19420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_RS19430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS19455	COG2197	response regulator
RvVAT039_RS19460	COG5002	protein histidine kinase activity
RvVAT039_RS19465	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
RvVAT039_RS19475	COG2205	protein histidine kinase activity
RvVAT039_RS19480	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS19490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RvVAT039_RS19510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RvVAT039_RS19520	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_RS19530	COG1309	transcriptional regulator
RvVAT039_RS19560	COG2207	Transcriptional regulator
RvVAT039_RS19570	COG0235	Class ii aldolase
RvVAT039_RS19590	COG0300	oxidoreductase activity
RvVAT039_RS19615	COG1595	DNA-templated transcription, initiation
RvVAT039_RS19625	COG2824	Alkylphosphonate utilization operon protein PhnA
RvVAT039_RS19650	COG3833	ABC-type maltose transport systems, permease component
RvVAT039_RS19655	COG3842	ATPase activity
RvVAT039_RS19660	COG0584	glycerophosphoryl diester phosphodiesterase
RvVAT039_RS19700	COG1320	monovalent cation:proton antiporter activity
RvVAT039_RS19705	COG2212	antiporter activity
RvVAT039_RS19710	COG1863	multisubunit Na H antiporter MnhE subunit
RvVAT039_RS19715	COG0651	ATP synthesis coupled electron transport
RvVAT039_RS19720	COG1006	Multisubunit Na H antiporter MnhC subunit
RvVAT039_RS19725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RvVAT039_RS19725	COG2111	Na H antiporter
RvVAT039_RS19760	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_RS19765	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_RS19780	COG2072	flavoprotein involved in K transport
RvVAT039_RS19785	COG1177	transmembrane transport
RvVAT039_RS19790	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_RS19795	COG3842	ATPase activity
RvVAT039_RS19800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RvVAT039_RS19805	COG0583	DNA-binding transcription factor activity
RvVAT039_RS19835	COG0444	Belongs to the ABC transporter superfamily
RvVAT039_RS19865	COG0601	transmembrane transport
RvVAT039_RS19870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS19890	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS19895	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS19900	COG1846	Transcriptional regulator
RvVAT039_RS19930	COG0625	glutathione transferase activity
RvVAT039_RS19950	COG2133	pyrroloquinoline quinone binding
RvVAT039_RS19960	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_RS19975	COG0753	catalase activity
RvVAT039_RS19980	COG0306	phosphate transporter
RvVAT039_RS19995	COG3684	Belongs to the aldolase LacD family
RvVAT039_RS20000	COG2390	Transcriptional regulator
RvVAT039_RS20020	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS20025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_RS20030	COG0626	cystathionine gamma-synthase activity
RvVAT039_RS20035	COG1725	Transcriptional regulator
RvVAT039_RS20040	COG0747	negative chemotaxis
RvVAT039_RS20055	COG0444	Belongs to the ABC transporter superfamily
RvVAT039_RS20060	COG4608	Belongs to the ABC transporter superfamily
RvVAT039_RS20065	COG0006	proline dipeptidase activity
RvVAT039_RS20075	COG0747	negative chemotaxis
RvVAT039_RS20090	COG0405	Gamma-glutamyltransferase
RvVAT039_RS20100	COG0754	glutathionylspermidine amidase activity
RvVAT039_RS20110	COG3766	membrane
RvVAT039_RS20120	COG3789	protein conserved in bacteria
RvVAT039_RS20135	COG0318	PFAM AMP-dependent synthetase and ligase
RvVAT039_RS20145	COG1802	Transcriptional regulator
RvVAT039_RS20155	COG0601	transmembrane transport
RvVAT039_RS20185	COG0747	negative chemotaxis
RvVAT039_RS20195	COG2205	protein histidine kinase activity
RvVAT039_RS20200	COG2197	response regulator
RvVAT039_RS20205	COG4585	Histidine kinase
RvVAT039_RS20220	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RvVAT039_RS20225	COG4208	sulfate ABC transporter
RvVAT039_RS20230	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RvVAT039_RS20235	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RvVAT039_RS20240	COG1609	Transcriptional regulator
RvVAT039_RS20245	COG0673	inositol 2-dehydrogenase activity
RvVAT039_RS20255	COG1653	transport
RvVAT039_RS20260	COG1175	transmembrane transport
RvVAT039_RS20265	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS20270	COG3842	ATPase activity
RvVAT039_RS20280	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RvVAT039_RS20295	COG0583	DNA-binding transcription factor activity
RvVAT039_RS20300	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_RS20305	COG3250	beta-galactosidase activity
RvVAT039_RS20310	COG1940	carbohydrate kinase activity
RvVAT039_RS20315	COG2116	formate transmembrane transporter activity
RvVAT039_RS20320	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_RS20365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RvVAT039_RS20370	COG0583	DNA-binding transcription factor activity
RvVAT039_RS20385	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RvVAT039_RS20400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RvVAT039_RS20405	COG2080	2 iron, 2 sulfur cluster binding
RvVAT039_RS20410	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS20425	COG2186	Transcriptional regulator
RvVAT039_RS20430	COG1304	FMN binding
RvVAT039_RS20440	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_RS20485	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RvVAT039_RS20490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RvVAT039_RS20495	COG1126	abc transporter atp-binding protein
RvVAT039_RS20500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_RS20505	COG0765	amino acid transport
RvVAT039_RS20510	COG0765	amino acid transport
RvVAT039_RS20515	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RvVAT039_RS20525	COG1764	response to oxidative stress
RvVAT039_RS20540	COG1116	anion transmembrane transporter activity
RvVAT039_RS20545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_RS20550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_RS20555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_RS20560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_RS20565	COG1959	2 iron, 2 sulfur cluster binding
RvVAT039_RS20590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_RS20600	COG1116	anion transmembrane transporter activity
RvVAT039_RS20610	COG4191	Histidine kinase
RvVAT039_RS20615	COG4566	intracellular signal transduction
RvVAT039_RS20620	COG1082	Xylose isomerase domain protein TIM barrel
RvVAT039_RS20625	COG3842	ATPase activity
RvVAT039_RS20630	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS20635	COG1175	transmembrane transport
RvVAT039_RS20670	COG1940	carbohydrate kinase activity
RvVAT039_RS20675	COG0747	negative chemotaxis
RvVAT039_RS20680	COG0601	transmembrane transport
RvVAT039_RS20685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS20695	COG4608	Belongs to the ABC transporter superfamily
RvVAT039_RS20700	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS20715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_RS20725	COG2076	Multidrug Resistance protein
RvVAT039_RS20745	COG2076	Multidrug Resistance protein
RvVAT039_RS20760	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_RS20775	COG2202	Pas domain
RvVAT039_RS20775	COG3920	Histidine kinase
RvVAT039_RS20785	COG0784	Response regulator, receiver
RvVAT039_RS20795	COG1162	GTPase activity
RvVAT039_RS20800	COG0784	Response regulator, receiver
RvVAT039_RS20800	COG4191	Histidine kinase
RvVAT039_RS20805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RvVAT039_RS20820	COG1126	abc transporter atp-binding protein
RvVAT039_RS20825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_RS20830	COG1609	Transcriptional regulator
RvVAT039_RS20835	COG0840	transmembrane signaling receptor activity
RvVAT039_RS20835	COG2972	Histidine kinase
RvVAT039_RS20840	COG0835	chemotaxis
RvVAT039_RS20845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_RS20850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RvVAT039_RS20865	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RvVAT039_RS20875	COG0789	Transcriptional regulator
RvVAT039_RS20880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RvVAT039_RS20885	COG0366	Alpha amylase catalytic
RvVAT039_RS20890	COG0366	Alpha amylase catalytic
RvVAT039_RS20895	COG1640	4-alpha-glucanotransferase
RvVAT039_RS20900	COG1278	Cold shock
RvVAT039_RS20905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RvVAT039_RS20915	COG0673	inositol 2-dehydrogenase activity
RvVAT039_RS20925	COG1802	Transcriptional regulator
RvVAT039_RS20930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RvVAT039_RS20940	COG0673	inositol 2-dehydrogenase activity
RvVAT039_RS20950	COG1175	transmembrane transport
RvVAT039_RS20955	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS20965	COG0673	inositol 2-dehydrogenase activity
RvVAT039_RS20975	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
RvVAT039_RS20985	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS20995	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
RvVAT039_RS21000	COG3920	Histidine kinase
RvVAT039_RS21015	COG3685	Protein conserved in bacteria
RvVAT039_RS21045	COG5001	Diguanylate cyclase
RvVAT039_RS21065	COG1132	(ABC) transporter
RvVAT039_RS21070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RvVAT039_RS21070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RvVAT039_RS21085	COG3842	ATPase activity
RvVAT039_RS21090	COG3833	ABC-type maltose transport systems, permease component
RvVAT039_RS21105	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RvVAT039_RS21135	COG3321	synthase
RvVAT039_RS21135	COG0604	alcohol dehydrogenase
RvVAT039_RS21155	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_RS21165	COG4608	Belongs to the ABC transporter superfamily
RvVAT039_RS21180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS21185	COG0747	negative chemotaxis
RvVAT039_RS21205	COG0583	DNA-binding transcription factor activity
RvVAT039_RS21210	COG0747	negative chemotaxis
RvVAT039_RS21220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS21235	COG0154	amidase activity
RvVAT039_RS21250	COG1335	isochorismatase
RvVAT039_RS21270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RvVAT039_RS21295	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_RS21300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS21305	COG0601	transmembrane transport
RvVAT039_RS21335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_RS21345	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS21355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_RS21360	COG1309	transcriptional regulator
RvVAT039_RS21375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RvVAT039_RS21390	COG4770	biotin carboxylase activity
RvVAT039_RS21405	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RvVAT039_RS21405	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RvVAT039_RS21420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_RS21425	COG1349	DNA-binding transcription factor activity
RvVAT039_RS21430	COG4608	Belongs to the ABC transporter superfamily
RvVAT039_RS21440	COG0601	transmembrane transport
RvVAT039_RS21515	COG1120	ATPase activity
RvVAT039_RS21520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_RS21525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_RS21530	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RvVAT039_RS21535	COG4774	siderophore transport
RvVAT039_RS21535	COG1629	transport
RvVAT039_RS21585	COG2226	methyltransferase
RvVAT039_RS21595	COG0318	PFAM AMP-dependent synthetase and ligase
RvVAT039_RS21615	COG0534	Mate efflux family protein
RvVAT039_RS21620	COG1959	2 iron, 2 sulfur cluster binding
RvVAT039_RS21655	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_RS21660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS21665	COG0601	transmembrane transport
RvVAT039_RS21670	COG0747	negative chemotaxis
RvVAT039_RS21675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_RS21700	COG1473	amidohydrolase
RvVAT039_RS21705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_RS21710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_RS21740	COG0662	Cupin 2, conserved barrel domain protein
RvVAT039_RS21765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RvVAT039_RS21785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RvVAT039_RS21795	COG0697	spore germination
RvVAT039_RS21825	COG3177	Filamentation induced by cAMP protein fic
RvVAT039_RS21885	COG0019	diaminopimelate decarboxylase activity
RvVAT039_RS21920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RvVAT039_RS21930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RvVAT039_RS21940	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_RS21950	COG1917	Cupin 2, conserved barrel domain protein
RvVAT039_RS21950	COG2207	Transcriptional regulator
RvVAT039_RS21955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_RS21960	COG1136	(ABC) transporter
RvVAT039_RS21995	COG3415	Transposase
RvVAT039_RS22000	COG3335	DDE superfamily endonuclease
RvVAT039_RS22020	COG2814	Major facilitator Superfamily
RvVAT039_RS22050	COG4214	carbohydrate transport
RvVAT039_RS22060	COG1069	ribulokinase activity
RvVAT039_RS22065	COG3177	Filamentation induced by cAMP protein fic
RvVAT039_RS22080	COG3971	2-oxopent-4-enoate hydratase activity
RvVAT039_RS22085	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_RS22100	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS22110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RvVAT039_RS22125	COG1846	Transcriptional regulator
RvVAT039_RS22140	COG2910	NAD(P)H-binding
RvVAT039_RS22145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RvVAT039_RS22150	COG0546	phosphoglycolate phosphatase activity
RvVAT039_RS22155	COG5441	Belongs to the UPF0261 family
RvVAT039_RS22160	COG1414	Transcriptional regulator
RvVAT039_RS22165	COG0531	amino acid
RvVAT039_RS22170	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS22220	COG1737	Transcriptional regulator
RvVAT039_RS22225	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS22230	COG1129	ABC transporter
RvVAT039_RS22255	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS22260	COG1175	transmembrane transport
RvVAT039_RS22270	COG3842	ATPase activity
RvVAT039_RS22285	COG2186	Transcriptional regulator
RvVAT039_RS22300	COG1175	transmembrane transport
RvVAT039_RS22305	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS22335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RvVAT039_RS22350	COG1175	transmembrane transport
RvVAT039_RS22355	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS22365	COG1940	carbohydrate kinase activity
RvVAT039_RS22385	COG0840	transmembrane signaling receptor activity
RvVAT039_RS22390	COG2223	nitrite transmembrane transporter activity
RvVAT039_RS22450	COG1126	abc transporter atp-binding protein
RvVAT039_RS22455	COG0765	amino acid transport
RvVAT039_RS22460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_RS22485	COG2226	methyltransferase
RvVAT039_RS22510	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
RvVAT039_RS22520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RvVAT039_RS22535	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RvVAT039_RS22545	COG2144	transferase activity, transferring acyl groups
RvVAT039_RS22550	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_RS22575	COG0243	molybdopterin cofactor binding
RvVAT039_RS22600	COG0395	ABC-type sugar transport system, permease component
RvVAT039_RS22615	COG1309	transcriptional regulator
RvVAT039_RS22625	COG0372	Belongs to the citrate synthase family
RvVAT039_RS22630	COG0372	Belongs to the citrate synthase family
RvVAT039_RS22635	COG1304	FMN binding
RvVAT039_RS22650	COG3181	Tripartite tricarboxylate transporter family receptor
RvVAT039_RS22660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RvVAT039_RS22665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RvVAT039_RS22680	COG1940	carbohydrate kinase activity
RvVAT039_RS22685	COG3842	ATPase activity
RvVAT039_RS22690	COG1177	transmembrane transport
RvVAT039_RS22710	COG3485	protocatechuate 3,4-dioxygenase
RvVAT039_RS22770	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_RS22790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RvVAT039_RS22795	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_RS22805	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS22820	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_RS22825	COG2271	Major facilitator Superfamily
RvVAT039_RS22835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RvVAT039_RS22855	COG1414	Transcriptional regulator
RvVAT039_RS22870	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_RS22880	COG1414	Transcriptional regulator
RvVAT039_RS22885	COG1902	pentaerythritol trinitrate reductase activity
RvVAT039_RS22890	COG0640	Transcriptional regulator
RvVAT039_RS22895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RvVAT039_RS22905	COG1780	Probably involved in ribonucleotide reductase function
RvVAT039_RS22915	COG0583	DNA-binding transcription factor activity
RvVAT039_RS22920	COG3842	ATPase activity
RvVAT039_RS22930	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS22975	COG0601	transmembrane transport
RvVAT039_RS22980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS22990	COG4608	Belongs to the ABC transporter superfamily
RvVAT039_RS23010	COG3485	protocatechuate 3,4-dioxygenase
RvVAT039_RS23030	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS23035	COG2814	Major facilitator Superfamily
RvVAT039_RS23040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RvVAT039_RS23055	COG1120	ATPase activity
RvVAT039_RS23060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_RS23065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_RS23075	COG0534	Mate efflux family protein
RvVAT039_RS23080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RvVAT039_RS23085	COG0019	diaminopimelate decarboxylase activity
RvVAT039_RS23110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS23115	COG1124	(ABC) transporter
RvVAT039_RS23120	COG3938	Belongs to the proline racemase family
RvVAT039_RS23125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_RS23140	COG1129	ABC transporter
RvVAT039_RS23145	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS23165	COG1595	DNA-templated transcription, initiation
RvVAT039_RS23175	COG0583	DNA-binding transcription factor activity
RvVAT039_RS23185	COG4221	oxidoreductase activity
RvVAT039_RS23185	COG0604	alcohol dehydrogenase
RvVAT039_RS23185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RvVAT039_RS23185	COG3321	synthase
RvVAT039_RS23200	COG3971	2-oxopent-4-enoate hydratase activity
RvVAT039_RS23205	COG3485	protocatechuate 3,4-dioxygenase
RvVAT039_RS23295	COG1414	Transcriptional regulator
RvVAT039_RS23350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_RS23355	COG3486	L-lysine 6-monooxygenase (NADPH) activity
RvVAT039_RS23360	COG2873	o-acetylhomoserine
RvVAT039_RS23385	COG2192	nodulation
RvVAT039_RS23435	COG3833	ABC-type maltose transport systems, permease component
RvVAT039_RS23440	COG3842	ATPase activity
RvVAT039_RS23445	COG3284	Transcriptional regulator
RvVAT039_RS23450	COG1063	alcohol dehydrogenase
RvVAT039_RS23460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RvVAT039_RS23470	COG0511	ligase activity, forming carbon-carbon bonds
RvVAT039_RS23475	COG0511	ligase activity, forming carbon-carbon bonds
RvVAT039_RS23485	COG1984	allophanate hydrolase subunit 2
RvVAT039_RS23490	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RvVAT039_RS23495	COG0436	Aminotransferase
RvVAT039_RS23505	COG4221	oxidoreductase activity
RvVAT039_RS23510	COG0765	amino acid transport
RvVAT039_RS23515	COG0765	amino acid transport
RvVAT039_RS23525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_RS23535	COG1609	Transcriptional regulator
RvVAT039_RS23550	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_RS23555	COG1735	metal-dependent hydrolase with the TIM-barrel fold
RvVAT039_RS23585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_RS23595	COG0745	RESPONSE REGULATOR receiver
RvVAT039_RS23600	COG2205	protein histidine kinase activity
RvVAT039_RS23610	COG1573	uracil-dna glycosylase
RvVAT039_RS23630	COG0137	argininosuccinate synthase activity
RvVAT039_RS23655	COG2814	Major facilitator Superfamily
RvVAT039_RS23660	COG1082	Xylose isomerase domain protein TIM barrel
RvVAT039_RS23665	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS23675	COG1940	carbohydrate kinase activity
RvVAT039_RS23685	COG0583	DNA-binding transcription factor activity
RvVAT039_RS23715	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RvVAT039_RS23735	COG3321	synthase
RvVAT039_RS23735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RvVAT039_RS23735	COG0300	oxidoreductase activity
RvVAT039_RS23735	COG4221	oxidoreductase activity
RvVAT039_RS23740	COG0300	oxidoreductase activity
RvVAT039_RS23740	COG3321	synthase
RvVAT039_RS23740	COG4221	oxidoreductase activity
RvVAT039_RS23740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RvVAT039_RS23745	COG0300	oxidoreductase activity
RvVAT039_RS23745	COG0318	PFAM AMP-dependent synthetase and ligase
RvVAT039_RS23745	COG3321	synthase
RvVAT039_RS23745	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_RS23745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RvVAT039_RS23750	COG4221	oxidoreductase activity
RvVAT039_RS23750	COG0300	oxidoreductase activity
RvVAT039_RS23750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RvVAT039_RS23750	COG3321	synthase
RvVAT039_RS23805	COG2986	histidine ammonia-lyase
RvVAT039_RS23815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RvVAT039_RS23840	COG0601	transmembrane transport
RvVAT039_RS23875	COG4608	Belongs to the ABC transporter superfamily
RvVAT039_RS23880	COG0444	Belongs to the ABC transporter superfamily
RvVAT039_RS23885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_RS23890	COG0601	transmembrane transport
RvVAT039_RS23900	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RvVAT039_RS23910	COG0463	Glycosyl transferase, family 2
RvVAT039_RS23915	COG2327	Polysaccharide pyruvyl transferase
RvVAT039_RS23950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_RS23970	COG3706	GGDEF domain
RvVAT039_RS23975	COG2072	flavoprotein involved in K transport
RvVAT039_RS23980	COG0640	Transcriptional regulator
RvVAT039_RS23985	COG1475	DNA binding
RvVAT039_RS23990	COG1192	Involved in chromosome partitioning
RvVAT039_RS23995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RvVAT039_RS24015	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
RvVAT039_RS24045	COG1744	ABC transporter substrate-binding protein PnrA-like
RvVAT039_RS24050	COG2188	Transcriptional regulator
RvVAT039_RS24060	COG0640	Transcriptional regulator
RvVAT039_RS24065	COG1475	DNA binding
RvVAT039_RS24070	COG1192	Involved in chromosome partitioning
RvVAT039_RS24080	COG4962	Type ii secretion system protein e
RvVAT039_RS24095	COG3451	type IV secretory pathway VirB4
RvVAT039_RS24100	COG5314	conjugation
RvVAT039_RS24110	COG3846	protein secretion by the type IV secretion system
RvVAT039_RS24115	COG3701	Conjugal transfer protein
RvVAT039_RS24160	COG0583	DNA-binding transcription factor activity
RvVAT039_RS24170	COG0145	ligase activity
RvVAT039_RS24275	COG3831	ATPase activity
RvVAT039_RS24280	COG0776	regulation of translation
RvVAT039_RS24285	COG5489	Protein of unknown function (DUF736)
RvVAT039_RS24300	COG0300	oxidoreductase activity
RvVAT039_RS24320	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_RS24330	COG0583	DNA-binding transcription factor activity
RvVAT039_RS24360	COG1475	DNA binding
RvVAT039_RS24395	COG3436	PFAM IS66 Orf2 family protein
RvVAT039_RS24400	COG2433	Pfam Transposase IS66
RvVAT039_RS24415	COG3547	Transposase (IS116 IS110 IS902 family)
RvVAT039_RS24445	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RvVAT039_RS24480	COG0789	Transcriptional regulator
RvVAT039_RS24495	COG2132	Multicopper oxidase
RvVAT039_RS24600	COG3550	peptidyl-serine autophosphorylation
RvVAT039_RS24605	COG1396	sequence-specific DNA binding
RvVAT039_RS24620	COG4778	phosphonate C-P lyase system protein PhnL
RvVAT039_RS24625	COG4107	phosphonate C-P lyase system protein PhnK
RvVAT039_RS24630	COG3627	carbon phosphorus lyase activity
RvVAT039_RS24635	COG3626	phosphonate metabolism
RvVAT039_RS24640	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
RvVAT039_RS24750	COG1196	nuclear chromosome segregation