locus-tag	class	description
C1N71_RS00010	COG0592	DNA-directed DNA polymerase activity
C1N71_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C1N71_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C1N71_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
C1N71_RS00035	COG0187	DNA topoisomerase II activity
C1N71_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1N71_RS00060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1N71_RS00070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N71_RS00085	COG0494	nUDIX hydrolase
C1N71_RS00105	COG0705	Rhomboid family
C1N71_RS00125	COG0515	serine threonine protein kinase
C1N71_RS00130	COG0515	serine threonine protein kinase
C1N71_RS00135	COG0768	penicillin binding
C1N71_RS00170	COG1063	alcohol dehydrogenase
C1N71_RS00175	COG0477	Major facilitator Superfamily
C1N71_RS00180	COG1309	transcriptional regulator
C1N71_RS00200	COG0628	permease
C1N71_RS00215	COG1276	copper resistance
C1N71_RS00215	COG2372	response to copper ion
C1N71_RS00220	COG2847	Copper chaperone PCu(A)C
C1N71_RS00225	COG2837	iron assimilation
C1N71_RS00235	COG1960	acyl-CoA dehydrogenase activity
C1N71_RS00240	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_RS00260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N71_RS00265	COG0640	Transcriptional regulator
C1N71_RS00270	COG1609	Transcriptional regulator
C1N71_RS00280	COG0601	transmembrane transport
C1N71_RS00290	COG0444	Belongs to the ABC transporter superfamily
C1N71_RS00295	COG4608	Belongs to the ABC transporter superfamily
C1N71_RS00320	COG0671	phosphoesterase, PA-phosphatase related
C1N71_RS00365	COG0640	Transcriptional regulator
C1N71_RS00380	COG0698	ribose 5-phosphate isomerase
C1N71_RS00385	COG1609	Transcriptional regulator
C1N71_RS00415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C1N71_RS00420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N71_RS00435	COG4166	transmembrane transport
C1N71_RS00465	COG1902	pentaerythritol trinitrate reductase activity
C1N71_RS00500	COG0181	hydroxymethylbilane synthase activity
C1N71_RS00505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C1N71_RS00510	COG3253	May function as heme-dependent peroxidase
C1N71_RS00515	COG1846	Transcriptional regulator
C1N71_RS00530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C1N71_RS00545	COG1595	DNA-templated transcription, initiation
C1N71_RS00590	COG3237	CsbD-like
C1N71_RS00595	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C1N71_RS00600	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS00615	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS00625	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C1N71_RS00640	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS00680	COG0477	Major facilitator Superfamily
C1N71_RS00705	COG0477	Major facilitator Superfamily
C1N71_RS00715	COG0028	Belongs to the TPP enzyme family
C1N71_RS00720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1N71_RS00725	COG2188	Transcriptional regulator
C1N71_RS00735	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C1N71_RS00750	COG0395	ABC-type sugar transport system, permease component
C1N71_RS00755	COG1175	transmembrane transport
C1N71_RS00785	COG1113	amino acid transport
C1N71_RS00795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1N71_RS00840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N71_RS00845	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_RS00865	COG2186	Transcriptional regulator
C1N71_RS00910	COG0753	catalase activity
C1N71_RS00930	COG0667	Aldo Keto reductase
C1N71_RS00950	COG0395	ABC-type sugar transport system, permease component
C1N71_RS00955	COG1175	transmembrane transport
C1N71_RS00965	COG1653	transport
C1N71_RS00970	COG1609	Transcriptional regulator
C1N71_RS00975	COG0366	Alpha amylase catalytic
C1N71_RS00985	COG2390	Transcriptional regulator
C1N71_RS00990	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N71_RS01000	COG1129	ABC transporter
C1N71_RS01010	COG1070	Carbohydrate kinase
C1N71_RS01015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C1N71_RS01035	COG1741	Belongs to the pirin family
C1N71_RS01050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C1N71_RS01060	COG4821	SIS domain
C1N71_RS01065	COG2188	Transcriptional regulator
C1N71_RS01075	COG3340	Belongs to the peptidase S51 family
C1N71_RS01160	COG2814	Major facilitator Superfamily
C1N71_RS01180	COG0113	porphobilinogen synthase activity
C1N71_RS01185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C1N71_RS01195	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
C1N71_RS01200	COG0738	Major facilitator superfamily
C1N71_RS01210	COG1131	(ABC) transporter
C1N71_RS01215	COG3559	Exporter of polyketide antibiotics
C1N71_RS01220	COG0534	Mate efflux family protein
C1N71_RS01235	COG0477	Major facilitator Superfamily
C1N71_RS01245	COG1302	Protein conserved in bacteria
C1N71_RS01250	COG3590	peptidase
C1N71_RS01280	COG0824	Thioesterase
C1N71_RS01290	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_RS01305	COG1316	TRANSCRIPTIONal
C1N71_RS01310	COG2814	Major facilitator Superfamily
C1N71_RS01335	COG0443	Heat shock 70 kDa protein
C1N71_RS01340	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C1N71_RS01345	COG0484	heat shock protein binding
C1N71_RS01350	COG0789	Transcriptional regulator
C1N71_RS01385	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N71_RS01385	COG2247	cell wall binding repeat
C1N71_RS01415	COG0542	response to heat
C1N71_RS01420	COG4702	Belongs to the UPF0303 family
C1N71_RS01445	COG2197	response regulator
C1N71_RS01450	COG1940	carbohydrate kinase activity
C1N71_RS01460	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C1N71_RS01475	COG0737	Belongs to the 5'-nucleotidase family
C1N71_RS01520	COG1668	transmembrane transport
C1N71_RS01525	COG4152	abc transporter atp-binding protein
C1N71_RS01530	COG2197	response regulator
C1N71_RS01535	COG4585	Histidine kinase
C1N71_RS01540	COG1702	phosphate starvation-inducible protein PhoH
C1N71_RS01570	COG0745	RESPONSE REGULATOR receiver
C1N71_RS01620	COG0803	Belongs to the bacterial solute-binding protein 9 family
C1N71_RS01630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1N71_RS01635	COG1120	ATPase activity
C1N71_RS01645	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C1N71_RS01675	COG2197	response regulator
C1N71_RS01685	COG0477	Major facilitator Superfamily
C1N71_RS01735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C1N71_RS01745	COG0823	Involved in the tonB-independent uptake of proteins
C1N71_RS01745	COG1506	peptidase
C1N71_RS01750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C1N71_RS01775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1N71_RS01800	COG0318	PFAM AMP-dependent synthetase and ligase
C1N71_RS01805	COG0047	phosphoribosylformylglycinamidine synthase activity
C1N71_RS01820	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C1N71_RS01825	COG0151	Belongs to the GarS family
C1N71_RS01835	COG2233	PERMEase
C1N71_RS01850	COG4581	dead DEAH box helicase
C1N71_RS01865	COG1362	aminopeptidase activity
C1N71_RS01905	COG0235	Class ii aldolase
C1N71_RS01910	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N71_RS01915	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N71_RS01920	COG1129	ABC transporter
C1N71_RS01935	COG3254	rhamnose metabolic process
C1N71_RS01945	COG3347	Dehydrogenase
C1N71_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS01950	COG1070	Carbohydrate kinase
C1N71_RS01960	COG0156	8-amino-7-oxononanoate synthase activity
C1N71_RS01965	COG1063	alcohol dehydrogenase
C1N71_RS01975	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C1N71_RS01995	COG1760	l-serine dehydratase
C1N71_RS02015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C1N71_RS02020	COG0531	amino acid
C1N71_RS02025	COG0463	Glycosyl transferase, family 2
C1N71_RS02050	COG0789	Transcriptional regulator
C1N71_RS02055	COG1116	anion transmembrane transporter activity
C1N71_RS02065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N71_RS02070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N71_RS02075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N71_RS02095	COG0514	ATP-dependent DNA helicase (RecQ)
C1N71_RS02110	COG2301	Belongs to the HpcH HpaI aldolase family
C1N71_RS02120	COG0477	Major facilitator Superfamily
C1N71_RS02130	COG1876	peptidase activity
C1N71_RS02155	COG0033	Phosphoglucomutase
C1N71_RS02170	COG3321	synthase
C1N71_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS02170	COG0604	alcohol dehydrogenase
C1N71_RS02195	COG1063	alcohol dehydrogenase
C1N71_RS02205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C1N71_RS02210	COG0561	phosphatase activity
C1N71_RS02220	COG1316	TRANSCRIPTIONal
C1N71_RS02255	COG1024	Enoyl-CoA hydratase
C1N71_RS02260	COG1024	Enoyl-CoA hydratase
C1N71_RS02265	COG1278	Cold shock
C1N71_RS02300	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C1N71_RS02305	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS02310	COG1917	Cupin 2, conserved barrel domain protein
C1N71_RS02310	COG2169	Transcriptional regulator
C1N71_RS02315	COG1064	alcohol dehydrogenase
C1N71_RS02365	COG0686	Belongs to the AlaDH PNT family
C1N71_RS02375	COG1764	response to oxidative stress
C1N71_RS02380	COG0025	NhaP-type Na H and K H
C1N71_RS02400	COG1846	Transcriptional regulator
C1N71_RS02410	COG0277	FAD linked oxidase domain protein
C1N71_RS02415	COG0406	alpha-ribazole phosphatase activity
C1N71_RS02435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1N71_RS02440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1N71_RS02445	COG3842	ATPase activity
C1N71_RS02450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1N71_RS02455	COG1177	transmembrane transport
C1N71_RS02460	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1N71_RS02475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C1N71_RS02490	COG2313	pseudouridylate synthase activity
C1N71_RS02535	COG0667	Aldo Keto reductase
C1N71_RS02545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C1N71_RS02550	COG1201	RNA secondary structure unwinding
C1N71_RS02565	COG0745	RESPONSE REGULATOR receiver
C1N71_RS02570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C1N71_RS02605	COG3012	SEC-C Motif Domain Protein
C1N71_RS02610	COG0569	domain protein
C1N71_RS02615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N71_RS02640	COG0017	Asparaginyl-tRNA synthetase
C1N71_RS02675	COG0785	Cytochrome C biogenesis protein
C1N71_RS02680	COG1333	cytochrome c biogenesis protein
C1N71_RS02685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1N71_RS02690	COG4948	Mandelate Racemase Muconate Lactonizing
C1N71_RS02715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C1N71_RS02740	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C1N71_RS02745	COG2326	polyphosphate kinase activity
C1N71_RS02760	COG2226	methyltransferase
C1N71_RS02765	COG0142	geranyltranstransferase activity
C1N71_RS02795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1N71_RS02800	COG1666	GTP binding
C1N71_RS02810	COG0741	lytic transglycosylase activity
C1N71_RS02810	COG0739	heme binding
C1N71_RS02810	COG1196	nuclear chromosome segregation
C1N71_RS02815	COG0366	Alpha amylase catalytic
C1N71_RS02830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1N71_RS02835	COG1090	epimerase
C1N71_RS02850	COG2030	dehydratase
C1N71_RS02860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C1N71_RS02870	COG0436	Aminotransferase
C1N71_RS02890	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C1N71_RS02895	COG0081	regulation of translation
C1N71_RS02900	COG2197	response regulator
C1N71_RS02905	COG4585	Histidine kinase
C1N71_RS02910	COG3321	synthase
C1N71_RS02910	COG4221	oxidoreductase activity
C1N71_RS02910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N71_RS02910	COG0604	alcohol dehydrogenase
C1N71_RS02930	COG0745	RESPONSE REGULATOR receiver
C1N71_RS02935	COG2205	protein histidine kinase activity
C1N71_RS02950	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C1N71_RS02955	COG0222	ribosome binding
C1N71_RS02965	COG3844	kynureninase activity
C1N71_RS02970	COG3046	protein related to deoxyribodipyrimidine photolyase
C1N71_RS02975	COG1132	(ABC) transporter
C1N71_RS02980	COG1940	carbohydrate kinase activity
C1N71_RS02980	COG1846	Transcriptional regulator
C1N71_RS02990	COG4214	carbohydrate transport
C1N71_RS03015	COG0477	Major facilitator Superfamily
C1N71_RS03020	COG0402	S-adenosylhomocysteine deaminase activity
C1N71_RS03025	COG2814	Major facilitator Superfamily
C1N71_RS03035	COG0433	COG0433 Predicted ATPase
C1N71_RS03060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C1N71_RS03080	COG0667	Aldo Keto reductase
C1N71_RS03090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C1N71_RS03095	COG0531	amino acid
C1N71_RS03110	COG0579	oxidoreductase
C1N71_RS03120	COG1435	thymidine kinase activity
C1N71_RS03135	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C1N71_RS03145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N71_RS03200	COG0494	nUDIX hydrolase
C1N71_RS03235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1N71_RS03235	COG1754	DNA topoisomerase type I activity
C1N71_RS03240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C1N71_RS03245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C1N71_RS03260	COG0747	negative chemotaxis
C1N71_RS03265	COG0601	transmembrane transport
C1N71_RS03270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N71_RS03275	COG4172	Belongs to the ABC transporter superfamily
C1N71_RS03295	COG1335	isochorismatase
C1N71_RS03300	COG2409	Drug exporters of the RND superfamily
C1N71_RS03325	COG1132	(ABC) transporter
C1N71_RS03330	COG1131	(ABC) transporter
C1N71_RS03345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N71_RS03355	COG0477	Major facilitator Superfamily
C1N71_RS03365	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C1N71_RS03370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1N71_RS03370	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1N71_RS03385	COG0180	Tryptophanyl-tRNA synthetase
C1N71_RS03390	COG0708	Exodeoxyribonuclease III
C1N71_RS03400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1N71_RS03415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C1N71_RS03430	COG2009	succinate dehydrogenase
C1N71_RS03440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C1N71_RS03445	COG0438	transferase activity, transferring glycosyl groups
C1N71_RS03455	COG1744	ABC transporter substrate-binding protein PnrA-like
C1N71_RS03465	COG3845	ABC transporter
C1N71_RS03470	COG4603	Belongs to the binding-protein-dependent transport system permease family
C1N71_RS03475	COG1079	Belongs to the binding-protein-dependent transport system permease family
C1N71_RS03500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C1N71_RS03505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N71_RS03515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N71_RS03535	COG2205	protein histidine kinase activity
C1N71_RS03540	COG0745	RESPONSE REGULATOR receiver
C1N71_RS03565	COG4770	biotin carboxylase activity
C1N71_RS03585	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N71_RS03585	COG2247	cell wall binding repeat
C1N71_RS03590	COG0424	maF-like protein
C1N71_RS03600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1N71_RS03620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1N71_RS03635	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C1N71_RS03655	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C1N71_RS03685	COG2340	Cysteine-rich secretory protein family
C1N71_RS03700	COG1215	transferase activity, transferring glycosyl groups
C1N71_RS03755	COG0463	Glycosyl transferase, family 2
C1N71_RS03765	COG1960	acyl-CoA dehydrogenase activity
C1N71_RS03800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N71_RS03805	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C1N71_RS03835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C1N71_RS03840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C1N71_RS03850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1N71_RS03860	COG1301	dicarboxylic acid transport
C1N71_RS03865	COG3290	protein histidine kinase activity
C1N71_RS03870	COG4565	transcriptional regulatory protein
C1N71_RS03875	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C1N71_RS03890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_RS03895	COG2084	Dehydrogenase
C1N71_RS03915	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS03925	COG1063	alcohol dehydrogenase
C1N71_RS03930	COG3265	gluconokinase activity
C1N71_RS03940	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C1N71_RS03945	COG0193	aminoacyl-tRNA hydrolase activity
C1N71_RS03960	COG3956	TIGRFAM MazG family protein
C1N71_RS03995	COG0124	histidyl-tRNA synthetase
C1N71_RS04000	COG0148	phosphopyruvate hydratase activity
C1N71_RS04025	COG0477	Major facilitator Superfamily
C1N71_RS04055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C1N71_RS04060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1N71_RS04070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C1N71_RS04125	COG0488	(ABC) transporter
C1N71_RS04175	COG1082	Xylose isomerase domain protein TIM barrel
C1N71_RS04180	COG0129	dihydroxy-acid dehydratase activity
C1N71_RS04190	COG0440	acetolactate synthase activity
C1N71_RS04195	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C1N71_RS04200	COG1940	carbohydrate kinase activity
C1N71_RS04200	COG1846	Transcriptional regulator
C1N71_RS04215	COG1175	transmembrane transport
C1N71_RS04220	COG0395	ABC-type sugar transport system, permease component
C1N71_RS04230	COG0673	inositol 2-dehydrogenase activity
C1N71_RS04275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N71_RS04295	COG0477	Major facilitator Superfamily
C1N71_RS04305	COG0473	3-isopropylmalate dehydrogenase activity
C1N71_RS04310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1N71_RS04315	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1N71_RS04320	COG2855	membrane
C1N71_RS04325	COG2066	Belongs to the glutaminase family
C1N71_RS04335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C1N71_RS04340	COG0492	ferredoxin-NADP+ reductase activity
C1N71_RS04360	COG4221	oxidoreductase activity
C1N71_RS04385	COG3971	2-oxopent-4-enoate hydratase activity
C1N71_RS04395	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_RS04405	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1N71_RS04410	COG0477	Major facilitator Superfamily
C1N71_RS04415	COG0569	domain protein
C1N71_RS04415	COG0189	ligase activity
C1N71_RS04420	COG0189	ligase activity
C1N71_RS04420	COG4067	protein conserved in archaea
C1N71_RS04435	COG1492	cobalamin metabolic process
C1N71_RS04510	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C1N71_RS04515	COG0066	3-isopropylmalate dehydratase activity
C1N71_RS04520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C1N71_RS04540	COG1254	Belongs to the acylphosphatase family
C1N71_RS04570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C1N71_RS04575	COG0012	GTP binding
C1N71_RS04585	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C1N71_RS04610	COG0702	epimerase
C1N71_RS04615	COG1733	regulation of RNA biosynthetic process
C1N71_RS04625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C1N71_RS04630	COG0740	serine-type endopeptidase activity
C1N71_RS04635	COG0740	serine-type endopeptidase activity
C1N71_RS04645	COG2318	DinB family
C1N71_RS04660	COG2814	Major facilitator Superfamily
C1N71_RS04680	COG0386	Belongs to the glutathione peroxidase family
C1N71_RS04685	COG2111	Na H antiporter
C1N71_RS04685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C1N71_RS04690	COG1006	Multisubunit Na H antiporter MnhC subunit
C1N71_RS04695	COG0651	ATP synthesis coupled electron transport
C1N71_RS04710	COG1320	monovalent cation:proton antiporter activity
C1N71_RS04715	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1N71_RS04720	COG0509	glycine decarboxylation via glycine cleavage system
C1N71_RS04725	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C1N71_RS04725	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C1N71_RS04765	COG4172	Belongs to the ABC transporter superfamily
C1N71_RS04770	COG1217	gtp-binding protein TYPA
C1N71_RS04790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C1N71_RS04810	COG2252	PERMEase
C1N71_RS04830	COG2171	N-acyltransferase activity
C1N71_RS04835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N71_RS04850	COG4122	O-methyltransferase activity
C1N71_RS04860	COG2211	Major facilitator Superfamily
C1N71_RS04860	COG2190	(PTS) system
C1N71_RS04905	COG0006	proline dipeptidase activity
C1N71_RS04925	COG0277	FAD linked oxidase domain protein
C1N71_RS04930	COG0204	Acyl-transferase
C1N71_RS04930	COG0318	PFAM AMP-dependent synthetase and ligase
C1N71_RS04960	COG0613	PHP domain protein
C1N71_RS04970	COG0513	Belongs to the DEAD box helicase family
C1N71_RS05015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N71_RS05020	COG1615	UPF0182 protein
C1N71_RS05045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1N71_RS05055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N71_RS05060	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C1N71_RS05090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C1N71_RS05095	COG1131	(ABC) transporter
C1N71_RS05120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C1N71_RS05125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C1N71_RS05130	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C1N71_RS05150	COG3537	Alpha-1,2-mannosidase
C1N71_RS05155	COG0586	Pfam SNARE associated Golgi protein
C1N71_RS05165	COG4221	oxidoreductase activity
C1N71_RS05175	COG2267	carboxylic ester hydrolase activity
C1N71_RS05180	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1N71_RS05195	COG1121	(ABC) transporter
C1N71_RS05245	COG3425	synthase
C1N71_RS05275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C1N71_RS05285	COG2884	Cell division ATP-binding protein ftsE
C1N71_RS05290	COG2177	Part of the ABC transporter FtsEX involved in
C1N71_RS05295	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C1N71_RS05315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N71_RS05315	COG0425	Belongs to the sulfur carrier protein TusA family
C1N71_RS05325	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS05330	COG0483	inositol monophosphate 1-phosphatase activity
C1N71_RS05345	COG1162	GTPase activity
C1N71_RS05350	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C1N71_RS05355	COG1595	DNA-templated transcription, initiation
C1N71_RS05370	COG0567	Dehydrogenase, E1 component
C1N71_RS05370	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_RS05405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C1N71_RS05415	COG3594	Acyltransferase
C1N71_RS05440	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C1N71_RS05445	COG0571	ribonuclease III activity
C1N71_RS05450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C1N71_RS05460	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_RS05495	COG2813	Specifically methylates the guanine in position
C1N71_RS05500	COG3739	integral membrane protein
C1N71_RS05540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_RS05550	COG0228	four-way junction DNA binding
C1N71_RS05555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C1N71_RS05570	COG0335	large ribosomal subunit rRNA binding
C1N71_RS05580	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C1N71_RS05600	COG0792	nuclease activity
C1N71_RS05630	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C1N71_RS05645	COG0052	Belongs to the universal ribosomal protein uS2 family
C1N71_RS05650	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C1N71_RS05655	COG0528	UMP kinase activity
C1N71_RS05660	COG0233	cytoplasmic translational termination
C1N71_RS05685	COG0628	permease
C1N71_RS05695	COG3118	belongs to the thioredoxin family
C1N71_RS05705	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C1N71_RS05710	COG0366	Alpha amylase catalytic
C1N71_RS05730	COG0482	sulfurtransferase activity
C1N71_RS05735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C1N71_RS05745	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C1N71_RS05760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C1N71_RS05765	COG1733	regulation of RNA biosynthetic process
C1N71_RS05790	COG0154	amidase activity
C1N71_RS05795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C1N71_RS05810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_RS05835	COG4721	ABC-type cobalt transport system, permease component
C1N71_RS05840	COG1122	ATPase activity
C1N71_RS05880	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C1N71_RS05895	COG0586	Pfam SNARE associated Golgi protein
C1N71_RS05910	COG0629	single-stranded DNA binding
C1N71_RS05940	COG1946	Acyl-CoA thioesterase
C1N71_RS05950	COG3573	Dehydrogenase
C1N71_RS05960	COG0668	transmembrane transport
C1N71_RS05970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C1N71_RS05975	COG0698	ribose 5-phosphate isomerase
C1N71_RS05990	COG2723	6-phospho-beta-galactosidase activity
C1N71_RS06015	COG0315	cyclic pyranopterin monophosphate synthase activity
C1N71_RS06015	COG0521	Mo-molybdopterin cofactor biosynthetic process
C1N71_RS06030	COG0315	cyclic pyranopterin monophosphate synthase activity
C1N71_RS06065	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C1N71_RS06095	COG0544	peptidyl-prolyl cis-trans isomerase activity
C1N71_RS06100	COG0740	serine-type endopeptidase activity
C1N71_RS06105	COG0740	serine-type endopeptidase activity
C1N71_RS06115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C1N71_RS06120	COG1120	ATPase activity
C1N71_RS06150	COG4106	trans-aconitate 2-methyltransferase activity
C1N71_RS06160	COG0525	valine-tRNA ligase activity
C1N71_RS06175	COG0477	Major facilitator Superfamily
C1N71_RS06180	COG1309	transcriptional regulator
C1N71_RS06195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C1N71_RS06200	COG0285	dihydrofolate synthase activity
C1N71_RS06210	COG0105	UTP biosynthetic process
C1N71_RS06220	COG1530	ribonuclease E activity
C1N71_RS06230	COG3214	Protein conserved in bacteria
C1N71_RS06235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C1N71_RS06240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C1N71_RS06245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C1N71_RS06250	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C1N71_RS06260	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C1N71_RS06270	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C1N71_RS06280	COG0799	negative regulation of ribosome biogenesis
C1N71_RS06285	COG1609	Transcriptional regulator
C1N71_RS06290	COG1175	transmembrane transport
C1N71_RS06320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1N71_RS06330	COG2514	catechol 2,3-dioxygenase activity
C1N71_RS06340	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C1N71_RS06355	COG1522	sequence-specific DNA binding
C1N71_RS06365	COG0022	dehydrogenase e1 component
C1N71_RS06370	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_RS06375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1N71_RS06395	COG1960	acyl-CoA dehydrogenase activity
C1N71_RS06405	COG1940	carbohydrate kinase activity
C1N71_RS06445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C1N71_RS06450	COG2154	pterin-4-alpha-carbinolamine dehydratase
C1N71_RS06465	COG0402	S-adenosylhomocysteine deaminase activity
C1N71_RS06485	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C1N71_RS06490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C1N71_RS06510	COG1846	Transcriptional regulator
C1N71_RS06525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C1N71_RS06530	COG0723	plastoquinol--plastocyanin reductase activity
C1N71_RS06535	COG2010	Cytochrome c
C1N71_RS06540	COG1845	cytochrome c oxidase, subunit III
C1N71_RS06545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C1N71_RS06555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C1N71_RS06560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1N71_RS06565	COG2376	Dihydroxyacetone kinase
C1N71_RS06570	COG1461	Dihydroxyacetone kinase
C1N71_RS06575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1N71_RS06575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N71_RS06575	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C1N71_RS06580	COG0477	Major facilitator Superfamily
C1N71_RS06590	COG1794	racemase activity, acting on amino acids and derivatives
C1N71_RS06620	COG2217	Heavy metal translocating P-type atpase
C1N71_RS06635	COG2207	Transcriptional regulator
C1N71_RS06635	COG3708	Transcriptional regulator
C1N71_RS06720	COG1937	Protein conserved in bacteria
C1N71_RS06725	COG2217	Heavy metal translocating P-type atpase
C1N71_RS06745	COG2608	mercury ion transmembrane transporter activity
C1N71_RS06760	COG1196	nuclear chromosome segregation
C1N71_RS06760	COG0741	lytic transglycosylase activity
C1N71_RS06760	COG0739	heme binding
C1N71_RS06770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N71_RS06775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N71_RS06780	COG0798	PFAM Bile acid sodium symporter
C1N71_RS06785	COG0492	ferredoxin-NADP+ reductase activity
C1N71_RS06795	COG0640	Transcriptional regulator
C1N71_RS06855	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C1N71_RS06860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C1N71_RS06915	COG0626	cystathionine gamma-synthase activity
C1N71_RS06930	COG1051	belongs to the nudix hydrolase family
C1N71_RS06950	COG0745	RESPONSE REGULATOR receiver
C1N71_RS06955	COG0477	Major facilitator Superfamily
C1N71_RS06960	COG1506	peptidase
C1N71_RS06960	COG4946	Tricorn protease homolog
C1N71_RS06960	COG0823	Involved in the tonB-independent uptake of proteins
C1N71_RS06965	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS06985	COG1216	Glycosyl transferase, family 2
C1N71_RS07000	COG0805	protein transport
C1N71_RS07005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1N71_RS07015	COG2378	regulation of single-species biofilm formation
C1N71_RS07030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N71_RS07050	COG0215	cysteine-tRNA ligase activity
C1N71_RS07055	COG1968	undecaprenyl-diphosphatase activity
C1N71_RS07060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N71_RS07080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C1N71_RS07105	COG0438	transferase activity, transferring glycosyl groups
C1N71_RS07125	COG0254	rRNA binding
C1N71_RS07130	COG1119	ATPase activity
C1N71_RS07135	COG0297	glycogen (starch) synthase activity
C1N71_RS07140	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N71_RS07145	COG0560	Phosphoserine phosphatase
C1N71_RS07155	COG3135	benzoate transporter
C1N71_RS07160	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS07180	COG2860	membrane
C1N71_RS07185	COG0488	(ABC) transporter
C1N71_RS07195	COG1131	(ABC) transporter
C1N71_RS07210	COG1268	BioY protein
C1N71_RS07230	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N71_RS07235	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N71_RS07240	COG1129	ABC transporter
C1N71_RS07245	COG1879	ABC-type sugar transport system periplasmic component
C1N71_RS07255	COG1609	Transcriptional regulator
C1N71_RS07265	COG2151	metal-sulfur cluster biosynthetic enzyme
C1N71_RS07270	COG0396	ATPase activity
C1N71_RS07280	COG0719	Fe-S assembly protein
C1N71_RS07285	COG0719	Fe-S assembly protein
C1N71_RS07295	COG0248	Ppx GppA phosphatase
C1N71_RS07300	COG0109	protoheme IX farnesyltransferase activity
C1N71_RS07310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C1N71_RS07315	COG0166	Belongs to the GPI family
C1N71_RS07330	COG0363	glucosamine-6-phosphate deaminase activity
C1N71_RS07340	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1N71_RS07345	COG0149	triose-phosphate isomerase activity
C1N71_RS07350	COG0126	phosphoglycerate kinase activity
C1N71_RS07360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C1N71_RS07365	COG1481	regulation of sporulation
C1N71_RS07370	COG1660	Displays ATPase and GTPase activities
C1N71_RS07375	COG0322	excinuclease ABC activity
C1N71_RS07385	COG0783	Belongs to the Dps family
C1N71_RS07390	COG4770	biotin carboxylase activity
C1N71_RS07395	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C1N71_RS07400	COG4336	lyase activity
C1N71_RS07405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C1N71_RS07410	COG1914	H( )-stimulated, divalent metal cation uptake system
C1N71_RS07420	COG0556	nucleotide-excision repair
C1N71_RS07430	COG0237	dephospho-CoA kinase activity
C1N71_RS07440	COG0539	negative regulation of cytoplasmic translation
C1N71_RS07465	COG2050	protein possibly involved in aromatic compounds catabolism
C1N71_RS07495	COG0069	glutamate synthase activity
C1N71_RS07495	COG0070	glutamate synthase
C1N71_RS07495	COG0067	glutamate synthase
C1N71_RS07500	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C1N71_RS07505	COG0159	tryptophan synthase activity
C1N71_RS07510	COG0133	tryptophan synthase activity
C1N71_RS07515	COG0134	indole-3-glycerol-phosphate synthase activity
C1N71_RS07535	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C1N71_RS07540	COG0107	imidazoleglycerol-phosphate synthase activity
C1N71_RS07545	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C1N71_RS07550	COG0140	phosphoribosyl-ATP diphosphatase activity
C1N71_RS07565	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C1N71_RS07575	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C1N71_RS07585	COG1758	RNA polymerase activity
C1N71_RS07590	COG0194	GDP metabolic process
C1N71_RS07595	COG0284	orotidine-5'-phosphate decarboxylase activity
C1N71_RS07600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C1N71_RS07605	COG0505	Belongs to the CarA family
C1N71_RS07615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1N71_RS07620	COG0540	Belongs to the ATCase OTCase family
C1N71_RS07625	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C1N71_RS07630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1N71_RS07635	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C1N71_RS07640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C1N71_RS07645	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C1N71_RS07650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C1N71_RS07655	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C1N71_RS07660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C1N71_RS07665	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C1N71_RS07670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C1N71_RS07675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C1N71_RS07685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C1N71_RS07700	COG1196	nuclear chromosome segregation
C1N71_RS07710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1N71_RS07715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N71_RS07720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N71_RS07730	COG2255	four-way junction helicase activity
C1N71_RS07735	COG0632	four-way junction helicase activity
C1N71_RS07740	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C1N71_RS07745	COG0217	transcriptional regulatory protein
C1N71_RS07765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C1N71_RS07815	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C1N71_RS07850	COG0183	Belongs to the thiolase family
C1N71_RS07855	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1N71_RS07855	COG1024	Enoyl-CoA hydratase
C1N71_RS07860	COG2890	protein-(glutamine-N5) methyltransferase activity
C1N71_RS07885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C1N71_RS07900	COG0756	dUTP diphosphatase activity
C1N71_RS07935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1N71_RS07950	COG0187	DNA topoisomerase II activity
C1N71_RS07960	COG1126	abc transporter atp-binding protein
C1N71_RS07965	COG0765	amino acid transport
C1N71_RS07970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N71_RS07975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1N71_RS07990	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C1N71_RS07995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N71_RS08000	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_RS08015	COG0174	glutamine synthetase
C1N71_RS08030	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C1N71_RS08045	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C1N71_RS08075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N71_RS08080	COG1349	DNA-binding transcription factor activity
C1N71_RS08090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N71_RS08090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N71_RS08090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N71_RS08115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C1N71_RS08125	COG2205	protein histidine kinase activity
C1N71_RS08125	COG0784	Response regulator, receiver
C1N71_RS08160	COG2204	response regulator
C1N71_RS08170	COG0477	Major facilitator Superfamily
C1N71_RS08185	COG2814	Major facilitator Superfamily
C1N71_RS08195	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C1N71_RS08210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N71_RS08215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C1N71_RS08220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1N71_RS08250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N71_RS08255	COG0006	proline dipeptidase activity
C1N71_RS08260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1N71_RS08265	COG1181	Belongs to the D-alanine--D-alanine ligase family
C1N71_RS08275	COG0154	amidase activity
C1N71_RS08280	COG2957	Belongs to the agmatine deiminase family
C1N71_RS08295	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C1N71_RS08320	COG0438	transferase activity, transferring glycosyl groups
C1N71_RS08330	COG0242	peptide deformylase activity
C1N71_RS08340	COG4608	Belongs to the ABC transporter superfamily
C1N71_RS08345	COG0358	DNA primase activity
C1N71_RS08350	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C1N71_RS08360	COG0423	glycine-tRNA ligase activity
C1N71_RS08375	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1N71_RS08380	COG1381	Involved in DNA repair and RecF pathway recombination
C1N71_RS08385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1N71_RS08395	COG1136	(ABC) transporter
C1N71_RS08395	COG0577	efflux transmembrane transporter activity
C1N71_RS08400	COG2197	response regulator
C1N71_RS08405	COG4585	Histidine kinase
C1N71_RS08425	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C1N71_RS08435	COG0537	adenosine 5'-monophosphoramidase activity
C1N71_RS08445	COG0484	heat shock protein binding
C1N71_RS08450	COG1420	regulation of RNA biosynthetic process
C1N71_RS08470	COG0481	GTPase activity
C1N71_RS08480	COG0268	Binds directly to 16S ribosomal RNA
C1N71_RS08485	COG1466	dna polymerase III delta subunit
C1N71_RS08505	COG0495	leucyl-tRNA aminoacylation
C1N71_RS08515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1N71_RS08515	COG0512	Glutamine amidotransferase of anthranilate synthase
C1N71_RS08530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C1N71_RS08535	COG4988	ABC transporter
C1N71_RS08540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C1N71_RS08540	COG2755	lipolytic protein G-D-S-L family
C1N71_RS08545	COG1294	oxidase, subunit
C1N71_RS08550	COG1271	oxidase subunit
C1N71_RS08560	COG1174	glycine betaine transport
C1N71_RS08565	COG1174	glycine betaine transport
C1N71_RS08570	COG0517	IMP dehydrogenase activity
C1N71_RS08570	COG1125	glycine betaine transport
C1N71_RS08575	COG1309	transcriptional regulator
C1N71_RS08580	COG2135	peptidase activity
C1N71_RS08625	COG0697	spore germination
C1N71_RS08630	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C1N71_RS08640	COG0477	Major facilitator Superfamily
C1N71_RS08655	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C1N71_RS08675	COG0167	dihydroorotate dehydrogenase activity
C1N71_RS08680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C1N71_RS08685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1N71_RS08700	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C1N71_RS08705	COG3599	regulation of cell shape
C1N71_RS08715	COG1799	cell septum assembly
C1N71_RS08725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C1N71_RS08735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C1N71_RS08740	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C1N71_RS08750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C1N71_RS08755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1N71_RS08765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C1N71_RS08770	COG0768	penicillin binding
C1N71_RS08775	COG0275	rRNA processing
C1N71_RS08780	COG2001	Belongs to the MraZ family
C1N71_RS08790	COG0142	geranyltranstransferase activity
C1N71_RS08805	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C1N71_RS08810	COG0204	Acyl-transferase
C1N71_RS08815	COG1022	Amp-dependent synthetase and ligase
C1N71_RS08830	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C1N71_RS08835	COG1192	Involved in chromosome partitioning
C1N71_RS08850	COG1716	ATPase activity
C1N71_RS08865	COG2818	Glycosylase
C1N71_RS08875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_RS08880	COG0183	Belongs to the thiolase family
C1N71_RS08895	COG0569	domain protein
C1N71_RS08900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N71_RS08920	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C1N71_RS08930	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
C1N71_RS08950	COG1278	Cold shock
C1N71_RS08955	COG0492	ferredoxin-NADP+ reductase activity
C1N71_RS08970	COG1309	transcriptional regulator
C1N71_RS08990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N71_RS09005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1N71_RS09050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N71_RS09065	COG2375	cellular response to nickel ion
C1N71_RS09070	COG2814	Major facilitator Superfamily
C1N71_RS09075	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C1N71_RS09125	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C1N71_RS09140	COG1160	GTP binding
C1N71_RS09145	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C1N71_RS09160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C1N71_RS09165	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C1N71_RS09200	COG0494	nUDIX hydrolase
C1N71_RS09205	COG0504	CTP synthase activity
C1N71_RS09210	COG0497	DNA recombination
C1N71_RS09215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C1N71_RS09240	COG0647	UMP catabolic process
C1N71_RS09270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1N71_RS09285	COG0165	Argininosuccinate lyase
C1N71_RS09295	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C1N71_RS09300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1N71_RS09305	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C1N71_RS09310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C1N71_RS09320	COG0072	phenylalanine-tRNA ligase activity
C1N71_RS09320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N71_RS09325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C1N71_RS09330	COG0765	amino acid transport
C1N71_RS09335	COG0765	amino acid transport
C1N71_RS09345	COG1126	abc transporter atp-binding protein
C1N71_RS09350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N71_RS09355	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C1N71_RS09360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C1N71_RS09365	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C1N71_RS09380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C1N71_RS09385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C1N71_RS09390	COG0131	Imidazoleglycerol-phosphate dehydratase
C1N71_RS09395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C1N71_RS09405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C1N71_RS09410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C1N71_RS09420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C1N71_RS09425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C1N71_RS09430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C1N71_RS09450	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C1N71_RS09460	COG1396	sequence-specific DNA binding
C1N71_RS09465	COG1058	Belongs to the CinA family
C1N71_RS09465	COG1546	Belongs to the CinA family
C1N71_RS09475	COG1674	ftsk spoiiie
C1N71_RS09480	COG0577	efflux transmembrane transporter activity
C1N71_RS09480	COG1136	(ABC) transporter
C1N71_RS09485	COG0577	efflux transmembrane transporter activity
C1N71_RS09485	COG1136	(ABC) transporter
C1N71_RS09495	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C1N71_RS09500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1N71_RS09510	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C1N71_RS09520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C1N71_RS09535	COG0612	Peptidase, M16
C1N71_RS09540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N71_RS09545	COG1185	polyribonucleotide nucleotidyltransferase activity
C1N71_RS09555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C1N71_RS09585	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C1N71_RS09605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C1N71_RS09625	COG2311	Membrane
C1N71_RS09640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C1N71_RS09645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C1N71_RS09645	COG3266	domain, Protein
C1N71_RS09660	COG0442	prolyl-tRNA aminoacylation
C1N71_RS09690	COG0714	Associated with various cellular activities
C1N71_RS09695	COG2814	Major facilitator Superfamily
C1N71_RS09700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C1N71_RS09710	COG0750	zinc metalloprotease
C1N71_RS09725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1N71_RS09730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N71_RS09755	COG0714	Associated with various cellular activities
C1N71_RS09770	COG0631	protein serine/threonine phosphatase activity
C1N71_RS09780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1N71_RS09785	COG0405	Gamma-glutamyltransferase
C1N71_RS09795	COG0667	Aldo Keto reductase
C1N71_RS09800	COG3022	response to hydroperoxide
C1N71_RS09805	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C1N71_RS09810	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C1N71_RS09815	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C1N71_RS09820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C1N71_RS09825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C1N71_RS09830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C1N71_RS09835	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C1N71_RS09840	COG0356	it plays a direct role in the translocation of protons across the membrane
C1N71_RS09850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1N71_RS09860	COG2890	protein-(glutamine-N5) methyltransferase activity
C1N71_RS09870	COG1045	serine acetyltransferase
C1N71_RS09895	COG0588	phosphoglycerate mutase activity
C1N71_RS09910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1N71_RS09915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1N71_RS09930	COG1178	ABC-type Fe3 transport system permease component
C1N71_RS09935	COG3842	ATPase activity
C1N71_RS09940	COG1840	ABC-type Fe3 transport system, periplasmic component
C1N71_RS09970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C1N71_RS09980	COG0083	homoserine kinase activity
C1N71_RS09990	COG0460	homoserine dehydrogenase
C1N71_RS10005	COG0018	arginyl-trna synthetase
C1N71_RS10035	COG2094	Belongs to the DNA glycosylase MPG family
C1N71_RS10045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N71_RS10055	COG1937	Protein conserved in bacteria
C1N71_RS10070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N71_RS10080	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
C1N71_RS10110	COG1842	Phage shock protein A
C1N71_RS10115	COG0297	glycogen (starch) synthase activity
C1N71_RS10130	COG0346	lactoylglutathione lyase activity
C1N71_RS10150	COG1131	(ABC) transporter
C1N71_RS10160	COG4585	Histidine kinase
C1N71_RS10165	COG2197	response regulator
C1N71_RS10175	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C1N71_RS10185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1N71_RS10195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N71_RS10205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N71_RS10215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1N71_RS10235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N71_RS10240	COG1120	ATPase activity
C1N71_RS10260	COG0714	Associated with various cellular activities
C1N71_RS10265	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
C1N71_RS10265	COG0778	Nitroreductase
C1N71_RS10270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C1N71_RS10275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1N71_RS10280	COG0742	ribosomal rna small subunit methyltransferase
C1N71_RS10300	COG2176	DNA-directed DNA polymerase activity
C1N71_RS10305	COG1322	Protein conserved in bacteria
C1N71_RS10310	COG2267	carboxylic ester hydrolase activity
C1N71_RS10330	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS10335	COG1309	transcriptional regulator
C1N71_RS10370	COG2271	Major facilitator Superfamily
C1N71_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS10410	COG2271	Major facilitator Superfamily
C1N71_RS10420	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C1N71_RS10430	COG0149	triose-phosphate isomerase activity
C1N71_RS10435	COG0698	ribose 5-phosphate isomerase
C1N71_RS10440	COG2376	Dihydroxyacetone kinase
C1N71_RS10445	COG0191	fructose-bisphosphate aldolase activity
C1N71_RS10465	COG1570	exodeoxyribonuclease VII activity
C1N71_RS10470	COG0477	Major facilitator Superfamily
C1N71_RS10480	COG1722	exodeoxyribonuclease VII activity
C1N71_RS10490	COG0114	fumarate hydratase activity
C1N71_RS10495	COG1505	serine-type exopeptidase activity
C1N71_RS10520	COG1966	Carbon starvation protein
C1N71_RS10530	COG2011	ABC-type metal ion transport system permease component
C1N71_RS10535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1N71_RS10550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C1N71_RS10560	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1N71_RS10580	COG0653	protein targeting
C1N71_RS10590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C1N71_RS10595	COG5401	PFAM Sporulation and spore germination
C1N71_RS10600	COG5002	protein histidine kinase activity
C1N71_RS10620	COG0488	(ABC) transporter
C1N71_RS10630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C1N71_RS10635	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C1N71_RS10640	COG0084	hydrolase, TatD family'
C1N71_RS10665	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N71_RS10710	COG1061	Type III restriction enzyme res subunit
C1N71_RS10725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1N71_RS10730	COG4585	Histidine kinase
C1N71_RS10740	COG0488	(ABC) transporter
C1N71_RS10765	COG1643	Atp-dependent helicase
C1N71_RS10775	COG0183	Belongs to the thiolase family
C1N71_RS10790	COG0656	L-ascorbic acid biosynthetic process
C1N71_RS10810	COG3281	Trehalose synthase
C1N71_RS10825	COG1316	TRANSCRIPTIONal
C1N71_RS10830	COG1086	Polysaccharide biosynthesis protein
C1N71_RS10840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N71_RS10875	COG0489	protein tyrosine kinase activity
C1N71_RS10880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N71_RS10885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C1N71_RS10915	COG1970	mechanosensitive ion channel activity
C1N71_RS10920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_RS10955	COG0791	NLP P60 protein
C1N71_RS10965	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C1N71_RS10975	COG1278	Cold shock
C1N71_RS10990	COG1061	Type III restriction enzyme res subunit
C1N71_RS10995	COG0745	RESPONSE REGULATOR receiver
C1N71_RS11000	COG2205	protein histidine kinase activity
C1N71_RS11010	COG0459	protein refolding
C1N71_RS11030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N71_RS11055	COG3842	ATPase activity
C1N71_RS11075	COG0215	cysteine-tRNA ligase activity
C1N71_RS11080	COG2390	Transcriptional regulator
C1N71_RS11090	COG3414	Phosphotransferase system galactitol-specific IIB component
C1N71_RS11095	COG3775	system Galactitol-specific IIC component
C1N71_RS11100	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_RS11105	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_RS11105	COG0022	dehydrogenase e1 component
C1N71_RS11110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C1N71_RS11115	COG0673	inositol 2-dehydrogenase activity
C1N71_RS11130	COG3732	PTS system glucitol sorbitol-specific
C1N71_RS11140	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C1N71_RS11140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C1N71_RS11145	COG1329	Transcriptional regulator
C1N71_RS11160	COG5002	protein histidine kinase activity
C1N71_RS11170	COG0588	phosphoglycerate mutase activity
C1N71_RS11185	COG0354	folic acid binding
C1N71_RS11190	COG4044	May play a role in the intracellular transport of hydrophobic ligands
C1N71_RS11200	COG0745	RESPONSE REGULATOR receiver
C1N71_RS11205	COG0454	-acetyltransferase
C1N71_RS11205	COG0456	acetyltransferase
C1N71_RS11210	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C1N71_RS11225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1N71_RS11290	COG2017	converts alpha-aldose to the beta-anomer
C1N71_RS11305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C1N71_RS11310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C1N71_RS11320	COG2814	Major facilitator Superfamily
C1N71_RS11335	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_RS11360	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_RS11370	COG0587	DNA-directed DNA polymerase activity
C1N71_RS11380	COG2186	Transcriptional regulator
C1N71_RS11385	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C1N71_RS11390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N71_RS11415	COG1640	4-alpha-glucanotransferase
C1N71_RS11430	COG0137	argininosuccinate synthase activity
C1N71_RS11435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1N71_RS11440	COG0363	glucosamine-6-phosphate deaminase activity
C1N71_RS11445	COG1846	Transcriptional regulator
C1N71_RS11445	COG1940	carbohydrate kinase activity
C1N71_RS11450	COG1472	Belongs to the glycosyl hydrolase 3 family
C1N71_RS11455	COG0395	ABC-type sugar transport system, permease component
C1N71_RS11460	COG1175	transmembrane transport
C1N71_RS11465	COG2182	Extracellular solute-binding protein
C1N71_RS11480	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C1N71_RS11490	COG1737	Transcriptional regulator
C1N71_RS11505	COG1132	(ABC) transporter
C1N71_RS11510	COG1132	(ABC) transporter
C1N71_RS11520	COG0138	bifunctional purine biosynthesis protein purh
C1N71_RS11535	COG2838	Isocitrate dehydrogenase
C1N71_RS11555	COG0045	succinate-CoA ligase (ADP-forming) activity
C1N71_RS11600	COG3290	protein histidine kinase activity
C1N71_RS11620	COG0259	pyridoxamine-phosphate oxidase activity
C1N71_RS11630	COG0584	glycerophosphoryl diester phosphodiesterase
C1N71_RS11660	COG4941	Belongs to the sigma-70 factor family
C1N71_RS11670	COG0385	Bile acid
C1N71_RS11680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C1N71_RS11680	COG0519	Catalyzes the synthesis of GMP from XMP
C1N71_RS11705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C1N71_RS11710	COG0516	GMP reductase activity
C1N71_RS11765	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C1N71_RS11785	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C1N71_RS11795	COG0802	atpase or kinase
C1N71_RS11805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1N71_RS11810	COG0736	holo-[acyl-carrier-protein] synthase activity
C1N71_RS11815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1N71_RS11820	COG1072	(Pantothenic acid kinase))
C1N71_RS11835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N71_RS11840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C1N71_RS11845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C1N71_RS11865	COG0101	tRNA pseudouridine synthase activity
C1N71_RS11870	COG0203	ribosomal protein L17
C1N71_RS11875	COG0202	RNA polymerase activity
C1N71_RS11880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C1N71_RS11885	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C1N71_RS11890	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C1N71_RS11895	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C1N71_RS11905	COG0246	Mannitol dehydrogenase
C1N71_RS11910	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N71_RS11910	COG2213	PTS system mannitol-specific
C1N71_RS11925	COG0563	adenylate kinase activity
C1N71_RS11935	COG0200	Binds to the 23S rRNA
C1N71_RS11940	COG1841	ribosomal large subunit assembly
C1N71_RS11945	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C1N71_RS11950	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C1N71_RS11955	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C1N71_RS11960	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C1N71_RS11965	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C1N71_RS11970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C1N71_RS11975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C1N71_RS11980	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C1N71_RS11985	COG0255	Belongs to the universal ribosomal protein uL29 family
C1N71_RS11990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C1N71_RS11995	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C1N71_RS12000	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C1N71_RS12005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C1N71_RS12010	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C1N71_RS12015	COG0089	rRNA binding
C1N71_RS12020	COG0088	Forms part of the polypeptide exit tunnel
C1N71_RS12025	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C1N71_RS12030	COG0051	transcription antitermination factor activity, RNA binding
C1N71_RS12035	COG0010	Belongs to the arginase family
C1N71_RS12040	COG1228	amidohydrolase
C1N71_RS12045	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C1N71_RS12050	COG2986	histidine ammonia-lyase
C1N71_RS12080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C1N71_RS12085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C1N71_RS12090	COG0049	tRNA binding
C1N71_RS12095	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C1N71_RS12160	COG1674	ftsk spoiiie
C1N71_RS12170	COG0515	serine threonine protein kinase
C1N71_RS12170	COG2815	serine threonine protein kinase
C1N71_RS12200	COG0714	Associated with various cellular activities
C1N71_RS12215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C1N71_RS12220	COG0085	RNA polymerase activity
C1N71_RS12265	COG3842	ATPase activity
C1N71_RS12275	COG1177	transmembrane transport
C1N71_RS12320	COG0456	acetyltransferase
C1N71_RS12325	COG1175	transmembrane transport
C1N71_RS12330	COG0395	ABC-type sugar transport system, permease component
C1N71_RS12345	COG0622	Phosphoesterase
C1N71_RS12390	COG0454	-acetyltransferase
C1N71_RS12415	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C1N71_RS12430	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
C1N71_RS12450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C1N71_RS12475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1N71_RS12480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1N71_RS12485	COG0302	gtp cyclohydrolase
C1N71_RS12490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1N71_RS12515	COG0037	tRNA processing
C1N71_RS12520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C1N71_RS12570	COG2197	response regulator
C1N71_RS12590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C1N71_RS12605	COG0671	phosphoesterase, PA-phosphatase related
C1N71_RS12610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C1N71_RS12630	COG4977	sequence-specific DNA binding
C1N71_RS12695	COG3545	Serine hydrolase
C1N71_RS12710	COG1253	flavin adenine dinucleotide binding
C1N71_RS12730	COG2267	carboxylic ester hydrolase activity
C1N71_RS12735	COG0477	Major facilitator Superfamily
C1N71_RS12740	COG3142	Participates in the control of copper homeostasis
C1N71_RS12745	COG0477	Major facilitator Superfamily
C1N71_RS12775	COG2814	Major facilitator Superfamily
C1N71_RS12780	COG0028	Belongs to the TPP enzyme family
C1N71_RS12790	COG0435	Glutathione S-transferase
C1N71_RS12805	COG0477	Major facilitator Superfamily
C1N71_RS12820	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS12845	COG1802	Transcriptional regulator
C1N71_RS12865	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C1N71_RS12895	COG0395	ABC-type sugar transport system, permease component
C1N71_RS12900	COG1175	transmembrane transport
C1N71_RS12915	COG2814	Major facilitator Superfamily
C1N71_RS12920	COG0463	Glycosyl transferase, family 2
C1N71_RS12965	COG4176	ABC-type proline glycine betaine transport system permease component
C1N71_RS12970	COG4175	Glycine betaine
C1N71_RS12970	COG0517	IMP dehydrogenase activity
C1N71_RS12995	COG4172	Belongs to the ABC transporter superfamily
C1N71_RS13005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N71_RS13010	COG0747	negative chemotaxis
C1N71_RS13015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N71_RS13020	COG0601	transmembrane transport
C1N71_RS13025	COG1414	Transcriptional regulator
C1N71_RS13030	COG2188	Transcriptional regulator
C1N71_RS13035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N71_RS13040	COG1070	Carbohydrate kinase
C1N71_RS13055	COG1653	transport
C1N71_RS13060	COG1175	transmembrane transport
C1N71_RS13065	COG0395	ABC-type sugar transport system, permease component
C1N71_RS13075	COG2314	TM2 domain
C1N71_RS13090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1N71_RS13095	COG1309	transcriptional regulator
C1N71_RS13105	COG3321	synthase
C1N71_RS13105	COG0604	alcohol dehydrogenase
C1N71_RS13110	COG1597	lipid kinase activity
C1N71_RS13115	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C1N71_RS13120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1N71_RS13125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1N71_RS13135	COG1396	sequence-specific DNA binding
C1N71_RS13225	COG0210	DNA helicase
C1N71_RS13250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1N71_RS13325	COG0531	amino acid
C1N71_RS13335	COG0561	phosphatase activity
C1N71_RS13360	COG0730	response to heat
C1N71_RS13375	COG0545	Peptidyl-prolyl cis-trans isomerase
C1N71_RS13385	COG2084	Dehydrogenase
C1N71_RS13390	COG0477	Major facilitator Superfamily
C1N71_RS13395	COG3959	Transketolase, thiamine diphosphate binding domain
C1N71_RS13400	COG3958	Transketolase
C1N71_RS13410	COG2188	Transcriptional regulator
C1N71_RS13415	COG0477	Major facilitator Superfamily
C1N71_RS13425	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS13435	COG2188	Transcriptional regulator
C1N71_RS13440	COG2084	Dehydrogenase
C1N71_RS13450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1N71_RS13455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1N71_RS13455	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1N71_RS13475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N71_RS13480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N71_RS13485	COG1120	ATPase activity
C1N71_RS13490	COG1832	CoA-binding protein
C1N71_RS13540	COG1305	Transglutaminase-like
C1N71_RS13570	COG0655	NAD(P)H dehydrogenase (quinone) activity
C1N71_RS13600	COG2205	protein histidine kinase activity
C1N71_RS13615	COG0822	iron-sulfur transferase activity
C1N71_RS13640	COG1834	amidinotransferase
C1N71_RS13715	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C1N71_RS13750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_RS13775	COG0717	Belongs to the dCTP deaminase family
C1N71_RS13800	COG0693	protein deglycase activity
C1N71_RS13815	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1N71_RS13820	COG2030	dehydratase
C1N71_RS13820	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_RS13880	COG2050	protein possibly involved in aromatic compounds catabolism
C1N71_RS13885	COG3396	Phenylacetate-CoA oxygenase
C1N71_RS13890	COG3460	Phenylacetate-CoA oxygenase
C1N71_RS13895	COG2151	metal-sulfur cluster biosynthetic enzyme
C1N71_RS13900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N71_RS13910	COG1024	Enoyl-CoA hydratase
C1N71_RS13930	COG0542	response to heat
C1N71_RS13935	COG0494	nUDIX hydrolase
C1N71_RS13970	COG0640	Transcriptional regulator
C1N71_RS14005	COG1780	Probably involved in ribonucleotide reductase function
C1N71_RS14010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1N71_RS14020	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS14035	COG3321	synthase
C1N71_RS14035	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS14035	COG0604	alcohol dehydrogenase
C1N71_RS14045	COG1929	Belongs to the glycerate kinase type-1 family
C1N71_RS14110	COG1058	Belongs to the CinA family
C1N71_RS14110	COG1546	Belongs to the CinA family
C1N71_RS14115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C1N71_RS14130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N71_RS14175	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C1N71_RS14180	COG0702	epimerase
C1N71_RS14215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C1N71_RS14230	COG1309	transcriptional regulator
C1N71_RS14235	COG0406	alpha-ribazole phosphatase activity
C1N71_RS14245	COG0776	regulation of translation
C1N71_RS14250	COG2364	Membrane
C1N71_RS14255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N71_RS14275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C1N71_RS14280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C1N71_RS14285	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C1N71_RS14290	COG0598	Magnesium transport protein CorA
C1N71_RS14325	COG1121	(ABC) transporter
C1N71_RS14335	COG1846	Transcriptional regulator
C1N71_RS14340	COG1764	response to oxidative stress
C1N71_RS14350	COG3321	synthase
C1N71_RS14350	COG0604	alcohol dehydrogenase
C1N71_RS14350	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_RS14365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1N71_RS14365	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C1N71_RS14370	COG0515	serine threonine protein kinase
C1N71_RS14370	COG2815	serine threonine protein kinase
C1N71_RS14380	COG0667	Aldo Keto reductase
C1N71_RS14395	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_RS14400	COG0022	dehydrogenase e1 component
C1N71_RS14410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C1N71_RS14415	COG1950	PFAM Membrane protein of
C1N71_RS14420	COG0604	alcohol dehydrogenase
C1N71_RS14435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N71_RS14450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C1N71_RS14490	COG3842	ATPase activity
C1N71_RS14495	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1N71_RS14500	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1N71_RS14505	COG1177	transmembrane transport
C1N71_RS14515	COG2897	thiosulfate sulfurtransferase activity
C1N71_RS14535	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C1N71_RS14540	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C1N71_RS14570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C1N71_RS14620	COG1136	(ABC) transporter
C1N71_RS14620	COG0577	efflux transmembrane transporter activity
C1N71_RS14655	COG0305	Participates in initiation and elongation during chromosome replication
C1N71_RS14665	COG2409	Drug exporters of the RND superfamily
C1N71_RS14675	COG2188	Transcriptional regulator
C1N71_RS14680	COG1263	PTS System
C1N71_RS14680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N71_RS14680	COG2190	(PTS) system
C1N71_RS14710	COG3290	protein histidine kinase activity
C1N71_RS14715	COG4565	transcriptional regulatory protein
C1N71_RS14725	COG0359	binds to the 23S rRNA
C1N71_RS14730	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C1N71_RS14735	COG0629	single-stranded DNA binding
C1N71_RS14740	COG0360	Binds together with S18 to 16S ribosomal RNA
C1N71_RS14745	COG0617	tRNA 3'-terminal CCA addition
C1N71_RS14770	COG3118	belongs to the thioredoxin family
C1N71_RS14785	COG0357	Ribosomal RNA small subunit methyltransferase G
C1N71_RS14795	COG0706	membrane insertase activity
C1N71_RS14800	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C1N71_RS14805	COG0594	ribonuclease P activity
C1N71_RS14810	COG0230	Belongs to the bacterial ribosomal protein bL34 family