locus-tag	class	description
ATC03_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ATC03_RS00010	COG0592	DNA-directed DNA polymerase activity
ATC03_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ATC03_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ATC03_RS00025	COG0187	DNA topoisomerase II activity
ATC03_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ATC03_RS00070	COG0705	Rhomboid family
ATC03_RS00070	COG0457	Tetratricopeptide repeat
ATC03_RS00090	COG2815	serine threonine protein kinase
ATC03_RS00090	COG0515	serine threonine protein kinase
ATC03_RS00095	COG0515	serine threonine protein kinase
ATC03_RS00100	COG0768	penicillin binding
ATC03_RS00115	COG1716	ATPase activity
ATC03_RS00120	COG1716	ATPase activity
ATC03_RS00145	COG1595	DNA-templated transcription, initiation
ATC03_RS00175	COG1136	(ABC) transporter
ATC03_RS00225	COG1252	NADH dehydrogenase
ATC03_RS00240	COG2211	Major facilitator Superfamily
ATC03_RS00265	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ATC03_RS00275	COG1064	alcohol dehydrogenase
ATC03_RS00300	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ATC03_RS00310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS00315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATC03_RS00320	COG3119	arylsulfatase activity
ATC03_RS00325	COG0657	acetylesterase activity
ATC03_RS00330	COG1309	transcriptional regulator
ATC03_RS00370	COG1733	regulation of RNA biosynthetic process
ATC03_RS00375	COG0277	FAD linked oxidase domain protein
ATC03_RS00390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATC03_RS00400	COG1864	DNA RNA non-specific endonuclease
ATC03_RS00400	COG3591	Belongs to the peptidase S1B family
ATC03_RS00425	COG2207	Transcriptional regulator
ATC03_RS00425	COG3708	Transcriptional regulator
ATC03_RS00430	COG5006	permease, DMT superfamily
ATC03_RS00460	COG2822	iron ion transport
ATC03_RS00465	COG2837	iron assimilation
ATC03_RS00485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATC03_RS00500	COG2197	response regulator
ATC03_RS00505	COG0386	Belongs to the glutathione peroxidase family
ATC03_RS00510	COG2195	Cleaves the N-terminal amino acid of tripeptides
ATC03_RS00545	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ATC03_RS00550	COG0738	Major facilitator superfamily
ATC03_RS00555	COG1063	alcohol dehydrogenase
ATC03_RS00560	COG0156	8-amino-7-oxononanoate synthase activity
ATC03_RS00565	COG4221	oxidoreductase activity
ATC03_RS00580	COG0534	Mate efflux family protein
ATC03_RS00585	COG3304	Inner membrane component domain
ATC03_RS00600	COG3590	peptidase
ATC03_RS00625	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ATC03_RS00630	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ATC03_RS00635	COG0423	glycine-tRNA ligase activity
ATC03_RS00640	COG0519	Catalyzes the synthesis of GMP from XMP
ATC03_RS00645	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ATC03_RS00665	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ATC03_RS00700	COG3253	May function as heme-dependent peroxidase
ATC03_RS00705	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ATC03_RS00710	COG0181	hydroxymethylbilane synthase activity
ATC03_RS00720	COG0113	porphobilinogen synthase activity
ATC03_RS00725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ATC03_RS00730	COG0025	NhaP-type Na H and K H
ATC03_RS00750	COG0714	Associated with various cellular activities
ATC03_RS00770	COG0631	protein serine/threonine phosphatase activity
ATC03_RS00795	COG1131	(ABC) transporter
ATC03_RS00825	COG1054	Belongs to the UPF0176 family
ATC03_RS00835	COG1280	lysine exporter protein (LysE YggA)
ATC03_RS00840	COG1024	Enoyl-CoA hydratase
ATC03_RS00850	COG2079	MmgE PrpD family protein
ATC03_RS00885	COG1733	regulation of RNA biosynthetic process
ATC03_RS00935	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_RS00940	COG0189	ligase activity
ATC03_RS00940	COG4067	protein conserved in archaea
ATC03_RS00945	COG0569	domain protein
ATC03_RS00945	COG0189	ligase activity
ATC03_RS00955	COG1725	Transcriptional regulator
ATC03_RS00995	COG1414	Transcriptional regulator
ATC03_RS01015	COG3104	oligopeptide transport
ATC03_RS01020	COG1216	Glycosyl transferase, family 2
ATC03_RS01025	COG2340	Cysteine-rich secretory protein family
ATC03_RS01030	COG2814	Major facilitator Superfamily
ATC03_RS01040	COG1940	carbohydrate kinase activity
ATC03_RS01045	COG2272	Belongs to the type-B carboxylesterase lipase family
ATC03_RS01050	COG2211	Major facilitator Superfamily
ATC03_RS01055	COG3152	Membrane
ATC03_RS01070	COG2211	Major facilitator Superfamily
ATC03_RS01080	COG1472	Belongs to the glycosyl hydrolase 3 family
ATC03_RS01095	COG2186	Transcriptional regulator
ATC03_RS01110	COG0693	protein deglycase activity
ATC03_RS01125	COG0667	Aldo Keto reductase
ATC03_RS01170	COG1070	Carbohydrate kinase
ATC03_RS01175	COG3347	Dehydrogenase
ATC03_RS01175	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS01185	COG4952	isomerase
ATC03_RS01195	COG1879	ABC-type sugar transport system periplasmic component
ATC03_RS01200	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATC03_RS01205	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATC03_RS01210	COG1129	ABC transporter
ATC03_RS01215	COG1609	Transcriptional regulator
ATC03_RS01220	COG1609	Transcriptional regulator
ATC03_RS01225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ATC03_RS01255	COG1470	cell adhesion involved in biofilm formation
ATC03_RS01255	COG0366	Alpha amylase catalytic
ATC03_RS01270	COG0095	Lipoate-protein ligase
ATC03_RS01280	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ATC03_RS01295	COG2723	6-phospho-beta-galactosidase activity
ATC03_RS01300	COG0395	ABC-type sugar transport system, permease component
ATC03_RS01315	COG1876	peptidase activity
ATC03_RS01335	COG2733	membrane
ATC03_RS01340	COG0077	Prephenate dehydratase
ATC03_RS01350	COG1597	lipid kinase activity
ATC03_RS01355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ATC03_RS01360	COG0561	phosphatase activity
ATC03_RS01365	COG1316	TRANSCRIPTIONal
ATC03_RS01375	COG1316	TRANSCRIPTIONal
ATC03_RS01390	COG0477	Major facilitator Superfamily
ATC03_RS01395	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ATC03_RS01415	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS01430	COG1609	Transcriptional regulator
ATC03_RS01435	COG0366	Alpha amylase catalytic
ATC03_RS01445	COG4209	transmembrane transport
ATC03_RS01450	COG0395	ABC-type sugar transport system, permease component
ATC03_RS01465	COG1131	(ABC) transporter
ATC03_RS01490	COG2274	protein secretion by the type I secretion system
ATC03_RS01515	COG0730	response to heat
ATC03_RS01540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ATC03_RS01550	COG0505	Belongs to the CarA family
ATC03_RS01555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ATC03_RS01585	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ATC03_RS01590	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ATC03_RS01595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ATC03_RS01615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ATC03_RS01625	COG0569	domain protein
ATC03_RS01630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ATC03_RS01670	COG0017	Asparaginyl-tRNA synthetase
ATC03_RS01675	COG0406	alpha-ribazole phosphatase activity
ATC03_RS01680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATC03_RS01685	COG0785	Cytochrome C biogenesis protein
ATC03_RS01690	COG1333	cytochrome c biogenesis protein
ATC03_RS01695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ATC03_RS01715	COG4948	Mandelate Racemase Muconate Lactonizing
ATC03_RS01720	COG1410	methionine synthase
ATC03_RS01720	COG0646	methionine synthase
ATC03_RS01735	COG1129	ABC transporter
ATC03_RS01770	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ATC03_RS01775	COG2326	polyphosphate kinase activity
ATC03_RS01785	COG2226	methyltransferase
ATC03_RS01790	COG0142	geranyltranstransferase activity
ATC03_RS01800	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ATC03_RS01815	COG1666	GTP binding
ATC03_RS01820	COG1609	Transcriptional regulator
ATC03_RS01835	COG2755	lipolytic protein G-D-S-L family
ATC03_RS01835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ATC03_RS01845	COG0739	heme binding
ATC03_RS01855	COG0366	Alpha amylase catalytic
ATC03_RS01860	COG2182	Extracellular solute-binding protein
ATC03_RS01865	COG1175	transmembrane transport
ATC03_RS01870	COG3833	ABC-type maltose transport systems, permease component
ATC03_RS01875	COG0366	Alpha amylase catalytic
ATC03_RS01890	COG2197	response regulator
ATC03_RS01905	COG1222	aaa ATPase
ATC03_RS02005	COG4974	Belongs to the 'phage' integrase family
ATC03_RS02015	COG1002	Type II restriction enzyme, methylase subunits
ATC03_RS02090	COG0640	Transcriptional regulator
ATC03_RS02105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATC03_RS02110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ATC03_RS02115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATC03_RS02120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATC03_RS02125	COG0492	ferredoxin-NADP+ reductase activity
ATC03_RS02140	COG1937	Protein conserved in bacteria
ATC03_RS02145	COG2217	Heavy metal translocating P-type atpase
ATC03_RS02190	COG1595	DNA-templated transcription, initiation
ATC03_RS02235	COG1609	Transcriptional regulator
ATC03_RS02250	COG2160	L-arabinose isomerase activity
ATC03_RS02255	COG2017	converts alpha-aldose to the beta-anomer
ATC03_RS02265	COG1846	Transcriptional regulator
ATC03_RS02270	COG0028	Belongs to the TPP enzyme family
ATC03_RS02275	COG1349	DNA-binding transcription factor activity
ATC03_RS02290	COG0395	ABC-type sugar transport system, permease component
ATC03_RS02295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATC03_RS02320	COG2409	Drug exporters of the RND superfamily
ATC03_RS02325	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ATC03_RS02350	COG0438	transferase activity, transferring glycosyl groups
ATC03_RS02355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ATC03_RS02375	COG0765	amino acid transport
ATC03_RS02380	COG1126	abc transporter atp-binding protein
ATC03_RS02450	COG0456	acetyltransferase
ATC03_RS02465	COG0477	Major facilitator Superfamily
ATC03_RS02475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS02480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS02495	COG0601	transmembrane transport
ATC03_RS02500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATC03_RS02510	COG4166	transmembrane transport
ATC03_RS02515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATC03_RS02575	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
ATC03_RS02590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ATC03_RS02595	COG4569	acetaldehyde dehydrogenase (acetylating) activity
ATC03_RS02600	COG3971	2-oxopent-4-enoate hydratase activity
ATC03_RS02625	COG3842	ATPase activity
ATC03_RS02645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ATC03_RS02695	COG2030	dehydratase
ATC03_RS02705	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ATC03_RS02725	COG2197	response regulator
ATC03_RS02735	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_RS02760	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ATC03_RS02765	COG2501	S4 domain
ATC03_RS02770	COG4941	Belongs to the sigma-70 factor family
ATC03_RS02800	COG0583	DNA-binding transcription factor activity
ATC03_RS02805	COG0436	Aminotransferase
ATC03_RS02825	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ATC03_RS02850	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ATC03_RS02855	COG0081	regulation of translation
ATC03_RS02870	COG0531	amino acid
ATC03_RS02875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ATC03_RS02880	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_RS02915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ATC03_RS02920	COG0765	amino acid transport
ATC03_RS02925	COG1126	abc transporter atp-binding protein
ATC03_RS02975	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_RS02985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATC03_RS03005	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ATC03_RS03025	COG1335	isochorismatase
ATC03_RS03030	COG1733	regulation of RNA biosynthetic process
ATC03_RS03035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ATC03_RS03045	COG1177	transmembrane transport
ATC03_RS03060	COG3842	ATPase activity
ATC03_RS03085	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ATC03_RS03100	COG0415	Belongs to the DNA photolyase family
ATC03_RS03140	COG4221	oxidoreductase activity
ATC03_RS03140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ATC03_RS03140	COG3321	synthase
ATC03_RS03140	COG0604	alcohol dehydrogenase
ATC03_RS03160	COG0673	inositol 2-dehydrogenase activity
ATC03_RS03165	COG1129	ABC transporter
ATC03_RS03170	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATC03_RS03220	COG1136	(ABC) transporter
ATC03_RS03240	COG0745	RESPONSE REGULATOR receiver
ATC03_RS03245	COG2205	protein histidine kinase activity
ATC03_RS03255	COG3291	Pkd domain containing protein
ATC03_RS03260	COG1082	Xylose isomerase domain protein TIM barrel
ATC03_RS03275	COG0477	Major facilitator Superfamily
ATC03_RS03305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ATC03_RS03310	COG0222	ribosome binding
ATC03_RS03325	COG1609	Transcriptional regulator
ATC03_RS03330	COG1653	transport
ATC03_RS03335	COG0395	ABC-type sugar transport system, permease component
ATC03_RS03340	COG1175	transmembrane transport
ATC03_RS03350	COG2814	Major facilitator Superfamily
ATC03_RS03355	COG1609	Transcriptional regulator
ATC03_RS03360	COG1653	transport
ATC03_RS03365	COG1175	transmembrane transport
ATC03_RS03370	COG0395	ABC-type sugar transport system, permease component
ATC03_RS03375	COG1132	(ABC) transporter
ATC03_RS03380	COG0477	Major facilitator Superfamily
ATC03_RS03415	COG1609	Transcriptional regulator
ATC03_RS03425	COG4213	ABC transporter substrate-binding protein
ATC03_RS03430	COG1129	ABC transporter
ATC03_RS03435	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATC03_RS03480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATC03_RS03485	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATC03_RS03510	COG3345	alpha-galactosidase
ATC03_RS03515	COG1609	Transcriptional regulator
ATC03_RS03520	COG3507	Belongs to the glycosyl hydrolase 43 family
ATC03_RS03525	COG3507	Belongs to the glycosyl hydrolase 43 family
ATC03_RS03560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATC03_RS03570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ATC03_RS03575	COG0531	amino acid
ATC03_RS03580	COG3507	Belongs to the glycosyl hydrolase 43 family
ATC03_RS03665	COG3973	AAA domain
ATC03_RS03675	COG0477	Major facilitator Superfamily
ATC03_RS03715	COG1609	Transcriptional regulator
ATC03_RS03725	COG1653	transport
ATC03_RS03735	COG0395	ABC-type sugar transport system, permease component
ATC03_RS03760	COG2197	response regulator
ATC03_RS03765	COG3850	Histidine kinase
ATC03_RS03775	COG1136	(ABC) transporter
ATC03_RS03790	COG2814	Major facilitator Superfamily
ATC03_RS03795	COG0598	Magnesium transport protein CorA
ATC03_RS03825	COG2161	toxin-antitoxin pair type II binding
ATC03_RS03830	COG4115	mRNA cleavage
ATC03_RS03840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ATC03_RS03860	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ATC03_RS03880	COG1846	Transcriptional regulator
ATC03_RS03885	COG3250	beta-galactosidase activity
ATC03_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS03945	COG0822	iron-sulfur transferase activity
ATC03_RS04000	COG0640	Transcriptional regulator
ATC03_RS04010	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS04035	COG2186	Transcriptional regulator
ATC03_RS04045	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATC03_RS04060	COG0596	Alpha beta hydrolase
ATC03_RS04065	COG3214	Protein conserved in bacteria
ATC03_RS04105	COG0456	acetyltransferase
ATC03_RS04110	COG1609	Transcriptional regulator
ATC03_RS04120	COG0395	ABC-type sugar transport system, permease component
ATC03_RS04125	COG1653	transport
ATC03_RS04155	COG0640	Transcriptional regulator
ATC03_RS04170	COG0300	oxidoreductase activity
ATC03_RS04195	COG1595	DNA-templated transcription, initiation
ATC03_RS04205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ATC03_RS04220	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
ATC03_RS04225	COG0251	oxidation-reduction process
ATC03_RS04230	COG4608	Belongs to the ABC transporter superfamily
ATC03_RS04235	COG4172	Belongs to the ABC transporter superfamily
ATC03_RS04240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATC03_RS04245	COG0601	transmembrane transport
ATC03_RS04290	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ATC03_RS04300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ATC03_RS04315	COG0662	Cupin 2, conserved barrel domain protein
ATC03_RS04365	COG1595	DNA-templated transcription, initiation
ATC03_RS04375	COG0596	Alpha beta hydrolase
ATC03_RS04390	COG4585	Histidine kinase
ATC03_RS04395	COG2197	response regulator
ATC03_RS04420	COG1253	flavin adenine dinucleotide binding
ATC03_RS04440	COG2205	protein histidine kinase activity
ATC03_RS04445	COG0745	RESPONSE REGULATOR receiver
ATC03_RS04485	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS04495	COG0492	ferredoxin-NADP+ reductase activity
ATC03_RS04515	COG1280	lysine exporter protein (LysE YggA)
ATC03_RS04530	COG0686	Belongs to the AlaDH PNT family
ATC03_RS04535	COG1609	Transcriptional regulator
ATC03_RS04540	COG1621	beta-fructofuranosidase activity
ATC03_RS04560	COG1621	beta-fructofuranosidase activity
ATC03_RS04570	COG1609	Transcriptional regulator
ATC03_RS04600	COG1175	transmembrane transport
ATC03_RS04605	COG0395	ABC-type sugar transport system, permease component
ATC03_RS04610	COG1609	Transcriptional regulator
ATC03_RS04615	COG1621	beta-fructofuranosidase activity
ATC03_RS04620	COG1621	beta-fructofuranosidase activity
ATC03_RS04625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATC03_RS04635	COG0542	response to heat
ATC03_RS04640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATC03_RS04685	COG1653	transport
ATC03_RS04690	COG1175	transmembrane transport
ATC03_RS04695	COG0395	ABC-type sugar transport system, permease component
ATC03_RS04700	COG1609	Transcriptional regulator
ATC03_RS04730	COG2197	response regulator
ATC03_RS04735	COG4585	Histidine kinase
ATC03_RS04765	COG3119	arylsulfatase activity
ATC03_RS04780	COG3250	beta-galactosidase activity
ATC03_RS04815	COG0494	nUDIX hydrolase
ATC03_RS04850	COG4702	Belongs to the UPF0303 family
ATC03_RS04855	COG1793	dna ligase
ATC03_RS04860	COG0406	alpha-ribazole phosphatase activity
ATC03_RS04920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATC03_RS04930	COG0477	Major facilitator Superfamily
ATC03_RS04940	COG0659	secondary active sulfate transmembrane transporter activity
ATC03_RS04945	COG4552	Acetyltransferase involved in intracellular survival and related
ATC03_RS04950	COG1132	(ABC) transporter
ATC03_RS04965	COG0673	inositol 2-dehydrogenase activity
ATC03_RS04970	COG1609	Transcriptional regulator
ATC03_RS04975	COG0673	inositol 2-dehydrogenase activity
ATC03_RS04985	COG4948	Mandelate Racemase Muconate Lactonizing
ATC03_RS04990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATC03_RS05000	COG1609	Transcriptional regulator
ATC03_RS05020	COG0673	inositol 2-dehydrogenase activity
ATC03_RS05035	COG1175	transmembrane transport
ATC03_RS05040	COG0395	ABC-type sugar transport system, permease component
ATC03_RS05065	COG1929	Belongs to the glycerate kinase type-1 family
ATC03_RS05080	COG4214	carbohydrate transport
ATC03_RS05095	COG1070	Carbohydrate kinase
ATC03_RS05100	COG2115	Belongs to the xylose isomerase family
ATC03_RS05105	COG1609	Transcriptional regulator
ATC03_RS05110	COG3507	Belongs to the glycosyl hydrolase 43 family
ATC03_RS05115	COG1472	Belongs to the glycosyl hydrolase 3 family
ATC03_RS05120	COG0395	ABC-type sugar transport system, permease component
ATC03_RS05125	COG1175	transmembrane transport
ATC03_RS05130	COG1653	transport
ATC03_RS05140	COG1309	transcriptional regulator
ATC03_RS05145	COG1053	succinate dehydrogenase
ATC03_RS05150	COG2814	Major facilitator Superfamily
ATC03_RS05155	COG0671	phosphoesterase, PA-phosphatase related
ATC03_RS05175	COG0395	ABC-type sugar transport system, permease component
ATC03_RS05185	COG0277	FAD linked oxidase domain protein
ATC03_RS05195	COG1472	Belongs to the glycosyl hydrolase 3 family
ATC03_RS05215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ATC03_RS05220	COG0590	tRNA wobble adenosine to inosine editing
ATC03_RS05225	COG2252	PERMEase
ATC03_RS05240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ATC03_RS05260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ATC03_RS05270	COG3257	ureidoglycine aminohydrolase activity
ATC03_RS05275	COG3622	Belongs to the hyi family
ATC03_RS05280	COG2084	Dehydrogenase
ATC03_RS05285	COG3960	tartronate-semialdehyde synthase activity
ATC03_RS05290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATC03_RS05330	COG0433	COG0433 Predicted ATPase
ATC03_RS05365	COG0385	Bile acid
ATC03_RS05370	COG2072	flavoprotein involved in K transport
ATC03_RS05380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ATC03_RS05405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ATC03_RS05420	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ATC03_RS05440	COG5002	protein histidine kinase activity
ATC03_RS05475	COG1414	Transcriptional regulator
ATC03_RS05480	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ATC03_RS05495	COG0800	Aldolase
ATC03_RS05500	COG0747	negative chemotaxis
ATC03_RS05505	COG0601	transmembrane transport
ATC03_RS05515	COG0444	Belongs to the ABC transporter superfamily
ATC03_RS05520	COG4608	Belongs to the ABC transporter superfamily
ATC03_RS05530	COG1486	melibiose metabolic process
ATC03_RS05540	COG0579	oxidoreductase
ATC03_RS05545	COG0488	(ABC) transporter
ATC03_RS05575	COG0489	protein tyrosine kinase activity
ATC03_RS05580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATC03_RS05655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ATC03_RS05660	COG1404	Belongs to the peptidase S8 family
ATC03_RS05670	COG0110	maltose O-acetyltransferase activity
ATC03_RS05705	COG2244	polysaccharide biosynthetic process
ATC03_RS05735	COG0438	transferase activity, transferring glycosyl groups
ATC03_RS05750	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_RS05765	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS05765	COG0300	oxidoreductase activity
ATC03_RS05765	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_RS05765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ATC03_RS05765	COG3321	synthase
ATC03_RS05780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ATC03_RS05810	COG0045	succinate-CoA ligase (ADP-forming) activity
ATC03_RS05835	COG0138	bifunctional purine biosynthesis protein purh
ATC03_RS05845	COG1834	amidinotransferase
ATC03_RS05850	COG1136	(ABC) transporter
ATC03_RS05850	COG0577	efflux transmembrane transporter activity
ATC03_RS05855	COG1136	(ABC) transporter
ATC03_RS05855	COG0577	efflux transmembrane transporter activity
ATC03_RS05875	COG1132	(ABC) transporter
ATC03_RS05880	COG1132	(ABC) transporter
ATC03_RS05885	COG0019	diaminopimelate decarboxylase activity
ATC03_RS05895	COG2197	response regulator
ATC03_RS05900	COG4585	Histidine kinase
ATC03_RS05915	COG0538	isocitrate dehydrogenase activity
ATC03_RS05920	COG1940	carbohydrate kinase activity
ATC03_RS05930	COG1175	transmembrane transport
ATC03_RS05935	COG0395	ABC-type sugar transport system, permease component
ATC03_RS05940	COG1472	Belongs to the glycosyl hydrolase 3 family
ATC03_RS05980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ATC03_RS05985	COG1349	DNA-binding transcription factor activity
ATC03_RS05990	COG0191	fructose-bisphosphate aldolase activity
ATC03_RS06005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATC03_RS06020	COG0395	ABC-type sugar transport system, permease component
ATC03_RS06025	COG1940	carbohydrate kinase activity
ATC03_RS06040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ATC03_RS06045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ATC03_RS06055	COG2089	acid synthase
ATC03_RS06080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ATC03_RS06085	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ATC03_RS06095	COG1349	DNA-binding transcription factor activity
ATC03_RS06100	COG2017	converts alpha-aldose to the beta-anomer
ATC03_RS06110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS06150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ATC03_RS06175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ATC03_RS06180	COG0745	RESPONSE REGULATOR receiver
ATC03_RS06190	COG3485	protocatechuate 3,4-dioxygenase
ATC03_RS06205	COG0588	phosphoglycerate mutase activity
ATC03_RS06215	COG5002	protein histidine kinase activity
ATC03_RS06220	COG0745	RESPONSE REGULATOR receiver
ATC03_RS06235	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ATC03_RS06235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ATC03_RS06240	COG0215	cysteine-tRNA ligase activity
ATC03_RS06255	COG3842	ATPase activity
ATC03_RS06280	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATC03_RS06295	COG1278	Cold shock
ATC03_RS06300	COG1470	cell adhesion involved in biofilm formation
ATC03_RS06305	COG0459	protein refolding
ATC03_RS06315	COG2205	protein histidine kinase activity
ATC03_RS06320	COG0745	RESPONSE REGULATOR receiver
ATC03_RS06330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ATC03_RS06340	COG1061	Type III restriction enzyme res subunit
ATC03_RS06355	COG1278	Cold shock
ATC03_RS06370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ATC03_RS06380	COG1388	LysM domain
ATC03_RS06380	COG0791	NLP P60 protein
ATC03_RS06380	COG3103	Sh3 type 3 domain protein
ATC03_RS06390	COG3942	CHAP domain
ATC03_RS06390	COG1388	LysM domain
ATC03_RS06415	COG1793	dna ligase
ATC03_RS06420	COG1522	sequence-specific DNA binding
ATC03_RS06425	COG0686	Belongs to the AlaDH PNT family
ATC03_RS06430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ATC03_RS06430	COG0425	Belongs to the sulfur carrier protein TusA family
ATC03_RS06440	COG1970	mechanosensitive ion channel activity
ATC03_RS06455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ATC03_RS06485	COG2814	Major facilitator Superfamily
ATC03_RS06500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS06505	COG0475	glutathione-regulated potassium exporter activity
ATC03_RS06530	COG0656	L-ascorbic acid biosynthetic process
ATC03_RS06545	COG2233	PERMEase
ATC03_RS06550	COG1643	Atp-dependent helicase
ATC03_RS06560	COG1331	Highly conserved protein containing a thioredoxin domain
ATC03_RS06565	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ATC03_RS06600	COG0484	heat shock protein binding
ATC03_RS06605	COG1362	aminopeptidase activity
ATC03_RS06615	COG1760	l-serine dehydratase
ATC03_RS06655	COG1131	(ABC) transporter
ATC03_RS06665	COG3548	integral membrane protein
ATC03_RS06670	COG1832	CoA-binding protein
ATC03_RS06675	COG2873	o-acetylhomoserine
ATC03_RS06680	COG2329	Antibiotic biosynthesis monooxygenase
ATC03_RS06685	COG2076	Multidrug Resistance protein
ATC03_RS06695	COG1476	TRANSCRIPTIONal
ATC03_RS06700	COG0604	alcohol dehydrogenase
ATC03_RS06715	COG2855	membrane
ATC03_RS06735	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATC03_RS06740	COG0084	hydrolase, TatD family'
ATC03_RS06745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ATC03_RS06750	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ATC03_RS06755	COG0488	(ABC) transporter
ATC03_RS06765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ATC03_RS06770	COG2011	ABC-type metal ion transport system permease component
ATC03_RS06790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ATC03_RS06795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ATC03_RS06800	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_RS06820	COG2149	membrane
ATC03_RS06825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ATC03_RS06830	COG2084	Dehydrogenase
ATC03_RS06845	COG0477	Major facilitator Superfamily
ATC03_RS06850	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS06860	COG1063	alcohol dehydrogenase
ATC03_RS06865	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ATC03_RS06870	COG0193	aminoacyl-tRNA hydrolase activity
ATC03_RS06875	COG2860	membrane
ATC03_RS06880	COG0328	RNA-DNA hybrid ribonuclease activity
ATC03_RS06895	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ATC03_RS06900	COG1280	lysine exporter protein (LysE YggA)
ATC03_RS06910	COG0124	histidyl-tRNA synthetase
ATC03_RS06915	COG0148	phosphopyruvate hydratase activity
ATC03_RS06930	COG1404	Belongs to the peptidase S8 family
ATC03_RS06960	COG0248	Ppx GppA phosphatase
ATC03_RS06995	COG1704	LemA family
ATC03_RS07000	COG0501	Belongs to the peptidase M48B family
ATC03_RS07005	COG3214	Protein conserved in bacteria
ATC03_RS07015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ATC03_RS07020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ATC03_RS07040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ATC03_RS07050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ATC03_RS07060	COG0114	fumarate hydratase activity
ATC03_RS07080	COG1570	exodeoxyribonuclease VII activity
ATC03_RS07085	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ATC03_RS07095	COG0191	fructose-bisphosphate aldolase activity
ATC03_RS07100	COG1494	fructose-1,6-bisphosphatase
ATC03_RS07130	COG1322	Protein conserved in bacteria
ATC03_RS07135	COG2176	DNA-directed DNA polymerase activity
ATC03_RS07160	COG0012	GTP binding
ATC03_RS07205	COG0488	(ABC) transporter
ATC03_RS07220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ATC03_RS07235	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ATC03_RS07255	COG2890	protein-(glutamine-N5) methyltransferase activity
ATC03_RS07270	COG2814	Major facilitator Superfamily
ATC03_RS07275	COG1104	cysteine desulfurase activity
ATC03_RS07285	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ATC03_RS07290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ATC03_RS07300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ATC03_RS07305	COG0509	glycine decarboxylation via glycine cleavage system
ATC03_RS07310	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ATC03_RS07310	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ATC03_RS07325	COG4166	transmembrane transport
ATC03_RS07345	COG1217	gtp-binding protein TYPA
ATC03_RS07350	COG0739	heme binding
ATC03_RS07355	COG1024	Enoyl-CoA hydratase
ATC03_RS07390	COG2171	N-acyltransferase activity
ATC03_RS07395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATC03_RS07415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATC03_RS07450	COG2239	Acts as a magnesium transporter
ATC03_RS07465	COG0006	proline dipeptidase activity
ATC03_RS07475	COG0613	PHP domain protein
ATC03_RS07480	COG0513	Belongs to the DEAD box helicase family
ATC03_RS07505	COG0210	DNA helicase
ATC03_RS07520	COG0210	DNA helicase
ATC03_RS07530	COG3480	Lon protease (S16) C-terminal proteolytic domain
ATC03_RS07535	COG1615	UPF0182 protein
ATC03_RS07580	COG0596	Alpha beta hydrolase
ATC03_RS07585	COG0628	permease
ATC03_RS07595	COG3973	AAA domain
ATC03_RS07600	COG4221	oxidoreductase activity
ATC03_RS07615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ATC03_RS07625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ATC03_RS07630	COG1215	transferase activity, transferring glycosyl groups
ATC03_RS07670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ATC03_RS07695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ATC03_RS07700	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ATC03_RS07705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ATC03_RS07715	COG0586	Pfam SNARE associated Golgi protein
ATC03_RS07770	COG1609	Transcriptional regulator
ATC03_RS07775	COG1063	alcohol dehydrogenase
ATC03_RS07825	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ATC03_RS07835	COG1228	amidohydrolase
ATC03_RS07845	COG2884	Cell division ATP-binding protein ftsE
ATC03_RS07850	COG2177	Part of the ABC transporter FtsEX involved in
ATC03_RS07855	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ATC03_RS07875	COG3537	Alpha-1,2-mannosidase
ATC03_RS07910	COG0483	inositol monophosphate 1-phosphatase activity
ATC03_RS07985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ATC03_RS08000	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ATC03_RS08005	COG1122	ATPase activity
ATC03_RS08010	COG0183	Belongs to the thiolase family
ATC03_RS08015	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_RS08020	COG1268	BioY protein
ATC03_RS08040	COG0129	dihydroxy-acid dehydratase activity
ATC03_RS08045	COG0028	Belongs to the TPP enzyme family
ATC03_RS08050	COG0440	acetolactate synthase activity
ATC03_RS08055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ATC03_RS08090	COG3142	Participates in the control of copper homeostasis
ATC03_RS08115	COG0477	Major facilitator Superfamily
ATC03_RS08125	COG0473	3-isopropylmalate dehydrogenase activity
ATC03_RS08130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ATC03_RS08135	COG0456	acetyltransferase
ATC03_RS08140	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATC03_RS08150	COG0583	DNA-binding transcription factor activity
ATC03_RS08155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ATC03_RS08175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ATC03_RS08210	COG0631	protein serine/threonine phosphatase activity
ATC03_RS08220	COG2815	serine threonine protein kinase
ATC03_RS08220	COG0515	serine threonine protein kinase
ATC03_RS08235	COG0714	Associated with various cellular activities
ATC03_RS08255	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ATC03_RS08260	COG0066	3-isopropylmalate dehydratase activity
ATC03_RS08265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ATC03_RS08270	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_RS08270	COG0204	Acyl-transferase
ATC03_RS08275	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ATC03_RS08280	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATC03_RS08300	COG0742	ribosomal rna small subunit methyltransferase
ATC03_RS08310	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ATC03_RS08315	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ATC03_RS08320	COG0714	Associated with various cellular activities
ATC03_RS08340	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ATC03_RS08345	COG0571	ribonuclease III activity
ATC03_RS08350	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ATC03_RS08360	COG1196	nuclear chromosome segregation
ATC03_RS08400	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ATC03_RS08405	COG0228	four-way junction DNA binding
ATC03_RS08410	COG1837	Belongs to the UPF0109 family
ATC03_RS08415	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ATC03_RS08420	COG0336	Belongs to the RNA methyltransferase TrmD family
ATC03_RS08430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ATC03_RS08435	COG0243	molybdopterin cofactor binding
ATC03_RS08440	COG2223	nitrite transmembrane transporter activity
ATC03_RS08450	COG1648	precorrin-2 dehydrogenase activity
ATC03_RS08450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ATC03_RS08455	COG2146	nitrite reductase [NAD(P)H] activity
ATC03_RS08455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ATC03_RS08475	COG0335	large ribosomal subunit rRNA binding
ATC03_RS08480	COG0681	Belongs to the peptidase S26 family
ATC03_RS08485	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ATC03_RS08495	COG0792	nuclease activity
ATC03_RS08515	COG4974	Belongs to the 'phage' integrase family
ATC03_RS08525	COG0052	Belongs to the universal ribosomal protein uS2 family
ATC03_RS08530	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ATC03_RS08535	COG0528	UMP kinase activity
ATC03_RS08540	COG0233	cytoplasmic translational termination
ATC03_RS08590	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ATC03_RS08595	COG0366	Alpha amylase catalytic
ATC03_RS08600	COG0058	SHG alpha-glucan phosphorylase activity
ATC03_RS08620	COG0482	sulfurtransferase activity
ATC03_RS08635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ATC03_RS08645	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATC03_RS08650	COG0154	amidase activity
ATC03_RS08655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATC03_RS08665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ATC03_RS08675	COG4721	ABC-type cobalt transport system, permease component
ATC03_RS08680	COG1122	ATPase activity
ATC03_RS08995	COG0582	viral genome integration into host DNA
ATC03_RS09005	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ATC03_RS09015	COG0475	glutathione-regulated potassium exporter activity
ATC03_RS09015	COG0569	domain protein
ATC03_RS09020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ATC03_RS09030	COG0667	Aldo Keto reductase
ATC03_RS09035	COG0629	single-stranded DNA binding
ATC03_RS09060	COG0723	plastoquinol--plastocyanin reductase activity
ATC03_RS09065	COG1946	Acyl-CoA thioesterase
ATC03_RS09085	COG0668	transmembrane transport
ATC03_RS09095	COG2197	response regulator
ATC03_RS09100	COG4585	Histidine kinase
ATC03_RS09140	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ATC03_RS09145	COG2132	Multicopper oxidase
ATC03_RS09165	COG0783	Belongs to the Dps family
ATC03_RS09180	COG0544	peptidyl-prolyl cis-trans isomerase activity
ATC03_RS09190	COG0740	serine-type endopeptidase activity
ATC03_RS09195	COG0740	serine-type endopeptidase activity
ATC03_RS09200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ATC03_RS09205	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ATC03_RS09210	COG3135	benzoate transporter
ATC03_RS09230	COG0756	dUTP diphosphatase activity
ATC03_RS09245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ATC03_RS09250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ATC03_RS09255	COG1024	Enoyl-CoA hydratase
ATC03_RS09255	COG1250	3-hydroxyacyl-CoA dehydrogenase
ATC03_RS09260	COG0183	Belongs to the thiolase family
ATC03_RS09265	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ATC03_RS09335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ATC03_RS09345	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ATC03_RS09355	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ATC03_RS09360	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ATC03_RS09370	COG0217	transcriptional regulatory protein
ATC03_RS09375	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ATC03_RS09380	COG0632	four-way junction helicase activity
ATC03_RS09385	COG2255	four-way junction helicase activity
ATC03_RS09395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATC03_RS09400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATC03_RS09405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ATC03_RS09430	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ATC03_RS09440	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATC03_RS09445	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ATC03_RS09455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ATC03_RS09460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ATC03_RS09465	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ATC03_RS09470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ATC03_RS09475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ATC03_RS09480	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ATC03_RS09485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ATC03_RS09500	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ATC03_RS09505	COG0540	Belongs to the ATCase OTCase family
ATC03_RS09510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATC03_RS09520	COG0505	Belongs to the CarA family
ATC03_RS09525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ATC03_RS09530	COG0284	orotidine-5'-phosphate decarboxylase activity
ATC03_RS09535	COG0194	GDP metabolic process
ATC03_RS09540	COG1758	RNA polymerase activity
ATC03_RS09550	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ATC03_RS09560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ATC03_RS09570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ATC03_RS09575	COG0140	phosphoribosyl-ATP diphosphatase activity
ATC03_RS09580	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ATC03_RS09585	COG0107	imidazoleglycerol-phosphate synthase activity
ATC03_RS09590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ATC03_RS09610	COG0134	indole-3-glycerol-phosphate synthase activity
ATC03_RS09615	COG0133	tryptophan synthase activity
ATC03_RS09620	COG0159	tryptophan synthase activity
ATC03_RS09625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ATC03_RS09630	COG0069	glutamate synthase activity
ATC03_RS09630	COG0070	glutamate synthase
ATC03_RS09630	COG0067	glutamate synthase
ATC03_RS09670	COG0539	negative regulation of cytoplasmic translation
ATC03_RS09675	COG0237	dephospho-CoA kinase activity
ATC03_RS09680	COG0556	nucleotide-excision repair
ATC03_RS09690	COG0322	excinuclease ABC activity
ATC03_RS09695	COG1660	Displays ATPase and GTPase activities
ATC03_RS09700	COG1481	regulation of sporulation
ATC03_RS09705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ATC03_RS09715	COG0126	phosphoglycerate kinase activity
ATC03_RS09720	COG0149	triose-phosphate isomerase activity
ATC03_RS09725	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ATC03_RS09735	COG0363	glucosamine-6-phosphate deaminase activity
ATC03_RS09750	COG0166	Belongs to the GPI family
ATC03_RS09755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ATC03_RS09765	COG0109	protoheme IX farnesyltransferase activity
ATC03_RS09775	COG1612	heme a metabolic process
ATC03_RS09795	COG0396	ATPase activity
ATC03_RS09800	COG2151	metal-sulfur cluster biosynthetic enzyme
ATC03_RS09805	COG0339	signal peptide processing
ATC03_RS09820	COG0525	valine-tRNA ligase activity
ATC03_RS09830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATC03_RS09840	COG0747	negative chemotaxis
ATC03_RS09850	COG2723	6-phospho-beta-galactosidase activity
ATC03_RS09855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ATC03_RS09860	COG0285	dihydrofolate synthase activity
ATC03_RS09870	COG0105	UTP biosynthetic process
ATC03_RS09880	COG1530	ribonuclease E activity
ATC03_RS09890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ATC03_RS09895	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ATC03_RS09900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ATC03_RS09905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ATC03_RS09910	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ATC03_RS09920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ATC03_RS09930	COG0799	negative regulation of ribosome biogenesis
ATC03_RS09965	COG1472	Belongs to the glycosyl hydrolase 3 family
ATC03_RS09970	COG2353	YceI-like domain
ATC03_RS09980	COG0488	(ABC) transporter
ATC03_RS10000	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS10005	COG0560	Phosphoserine phosphatase
ATC03_RS10010	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ATC03_RS10015	COG0297	glycogen (starch) synthase activity
ATC03_RS10020	COG1119	ATPase activity
ATC03_RS10025	COG0254	rRNA binding
ATC03_RS10035	COG2267	carboxylic ester hydrolase activity
ATC03_RS10045	COG0406	alpha-ribazole phosphatase activity
ATC03_RS10075	COG2814	Major facilitator Superfamily
ATC03_RS10090	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS10100	COG0587	DNA-directed DNA polymerase activity
ATC03_RS10120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATC03_RS10125	COG1968	undecaprenyl-diphosphatase activity
ATC03_RS10135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ATC03_RS10145	COG0545	Peptidyl-prolyl cis-trans isomerase
ATC03_RS10160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATC03_RS10165	COG0805	protein transport
ATC03_RS10170	COG4581	dead DEAH box helicase
ATC03_RS10185	COG0584	glycerophosphoryl diester phosphodiesterase
ATC03_RS10200	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS10220	COG1396	sequence-specific DNA binding
ATC03_RS10225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATC03_RS10230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATC03_RS10240	COG1063	alcohol dehydrogenase
ATC03_RS10245	COG0640	Transcriptional regulator
ATC03_RS10250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ATC03_RS10260	COG0490	domain, Protein
ATC03_RS10260	COG0471	metal ion transport
ATC03_RS10270	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS10280	COG1461	Dihydroxyacetone kinase
ATC03_RS10285	COG2376	Dihydroxyacetone kinase
ATC03_RS10290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ATC03_RS10295	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ATC03_RS10300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ATC03_RS10305	COG1845	cytochrome c oxidase, subunit III
ATC03_RS10310	COG2010	Cytochrome c
ATC03_RS10315	COG0723	plastoquinol--plastocyanin reductase activity
ATC03_RS10320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ATC03_RS10325	COG2226	methyltransferase
ATC03_RS10335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ATC03_RS10340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ATC03_RS10350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATC03_RS10365	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ATC03_RS10370	COG0187	DNA topoisomerase II activity
ATC03_RS10385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ATC03_RS10390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATC03_RS10400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ATC03_RS10405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ATC03_RS10410	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATC03_RS10420	COG0321	lipoyl(octanoyl) transferase activity
ATC03_RS10425	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ATC03_RS10440	COG0174	glutamine synthetase
ATC03_RS10445	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ATC03_RS10450	COG0174	glutamine synthetase
ATC03_RS10455	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ATC03_RS10485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ATC03_RS10500	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ATC03_RS10515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ATC03_RS10520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATC03_RS10525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ATC03_RS10560	COG2353	YceI-like domain
ATC03_RS10585	COG0783	Belongs to the Dps family
ATC03_RS10590	COG1063	alcohol dehydrogenase
ATC03_RS10595	COG3546	catalase activity
ATC03_RS10660	COG1216	Glycosyl transferase, family 2
ATC03_RS10665	COG0583	DNA-binding transcription factor activity
ATC03_RS10680	COG1132	(ABC) transporter
ATC03_RS10690	COG0183	Belongs to the thiolase family
ATC03_RS10705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ATC03_RS10715	COG3485	protocatechuate 3,4-dioxygenase
ATC03_RS10720	COG3485	protocatechuate 3,4-dioxygenase
ATC03_RS10735	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATC03_RS10745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ATC03_RS10755	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATC03_RS10765	COG2814	Major facilitator Superfamily
ATC03_RS10775	COG2197	response regulator
ATC03_RS10820	COG2124	cytochrome p450
ATC03_RS10830	COG1414	Transcriptional regulator
ATC03_RS10835	COG1472	Belongs to the glycosyl hydrolase 3 family
ATC03_RS10840	COG3250	beta-galactosidase activity
ATC03_RS10845	COG0395	ABC-type sugar transport system, permease component
ATC03_RS10850	COG1175	transmembrane transport
ATC03_RS10860	COG1609	Transcriptional regulator
ATC03_RS10895	COG2094	Belongs to the DNA glycosylase MPG family
ATC03_RS10900	COG2140	Oxalate decarboxylase
ATC03_RS10915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ATC03_RS10920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ATC03_RS10925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ATC03_RS10935	COG2197	response regulator
ATC03_RS10945	COG2837	iron assimilation
ATC03_RS10960	COG3189	MarR family transcriptional regulator
ATC03_RS10970	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ATC03_RS10990	COG1122	ATPase activity
ATC03_RS11030	COG1024	Enoyl-CoA hydratase
ATC03_RS11035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ATC03_RS11055	COG1472	Belongs to the glycosyl hydrolase 3 family
ATC03_RS11085	COG4948	Mandelate Racemase Muconate Lactonizing
ATC03_RS11090	COG0246	Mannitol dehydrogenase
ATC03_RS11095	COG1904	glucuronate isomerase
ATC03_RS11100	COG3250	beta-galactosidase activity
ATC03_RS11105	COG2207	Transcriptional regulator
ATC03_RS11110	COG2211	Major facilitator Superfamily
ATC03_RS11110	COG2190	(PTS) system
ATC03_RS11130	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS11140	COG3250	beta-galactosidase activity
ATC03_RS11145	COG2814	Major facilitator Superfamily
ATC03_RS11225	COG0601	transmembrane transport
ATC03_RS11235	COG0358	DNA primase activity
ATC03_RS11250	COG0442	prolyl-tRNA aminoacylation
ATC03_RS11255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ATC03_RS11255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ATC03_RS11280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ATC03_RS11285	COG1381	Involved in DNA repair and RecF pathway recombination
ATC03_RS11295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ATC03_RS11300	COG0577	efflux transmembrane transporter activity
ATC03_RS11305	COG1136	(ABC) transporter
ATC03_RS11310	COG2197	response regulator
ATC03_RS11315	COG4585	Histidine kinase
ATC03_RS11320	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ATC03_RS11330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ATC03_RS11340	COG0537	adenosine 5'-monophosphoramidase activity
ATC03_RS11350	COG0484	heat shock protein binding
ATC03_RS11355	COG1420	regulation of RNA biosynthetic process
ATC03_RS11370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ATC03_RS11375	COG4762	Protein conserved in bacteria
ATC03_RS11380	COG0481	GTPase activity
ATC03_RS11385	COG4585	Histidine kinase
ATC03_RS11390	COG2197	response regulator
ATC03_RS11395	COG0268	Binds directly to 16S ribosomal RNA
ATC03_RS11415	COG0495	leucyl-tRNA aminoacylation
ATC03_RS11420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ATC03_RS11420	COG0512	Glutamine amidotransferase of anthranilate synthase
ATC03_RS11425	COG1132	(ABC) transporter
ATC03_RS11435	COG1294	oxidase, subunit
ATC03_RS11440	COG1271	oxidase subunit
ATC03_RS11450	COG0501	Belongs to the peptidase M48B family
ATC03_RS11455	COG0586	Pfam SNARE associated Golgi protein
ATC03_RS11470	COG1174	glycine betaine transport
ATC03_RS11475	COG0517	IMP dehydrogenase activity
ATC03_RS11475	COG1125	glycine betaine transport
ATC03_RS11490	COG0167	dihydroorotate dehydrogenase activity
ATC03_RS11495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ATC03_RS11500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ATC03_RS11505	COG0587	DNA-directed DNA polymerase activity
ATC03_RS11515	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ATC03_RS11520	COG3599	regulation of cell shape
ATC03_RS11530	COG1799	cell septum assembly
ATC03_RS11535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ATC03_RS11540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ATC03_RS11550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ATC03_RS11555	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ATC03_RS11565	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ATC03_RS11570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATC03_RS11580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ATC03_RS11595	COG0275	rRNA processing
ATC03_RS11600	COG2001	Belongs to the MraZ family
ATC03_RS11610	COG0142	geranyltranstransferase activity
ATC03_RS11620	COG3942	CHAP domain
ATC03_RS11620	COG1388	LysM domain
ATC03_RS11625	COG2815	serine threonine protein kinase
ATC03_RS11625	COG0515	serine threonine protein kinase
ATC03_RS11630	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ATC03_RS11640	COG1940	carbohydrate kinase activity
ATC03_RS11660	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ATC03_RS11665	COG1192	Involved in chromosome partitioning
ATC03_RS11710	COG0142	geranyltranstransferase activity
ATC03_RS11755	COG3012	SEC-C Motif Domain Protein
ATC03_RS11765	COG2357	RelA SpoT domain protein
ATC03_RS11790	COG0204	Acyl-transferase
ATC03_RS11810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATC03_RS11815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATC03_RS11840	COG0385	Bile acid
ATC03_RS11850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ATC03_RS11855	COG1695	Transcriptional regulator
ATC03_RS11860	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATC03_RS11885	COG2205	protein histidine kinase activity
ATC03_RS11890	COG0745	RESPONSE REGULATOR receiver
ATC03_RS11910	COG0531	amino acid
ATC03_RS11915	COG1917	Cupin 2, conserved barrel domain protein
ATC03_RS11915	COG1396	sequence-specific DNA binding
ATC03_RS11930	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ATC03_RS11985	COG0785	Cytochrome C biogenesis protein
ATC03_RS11990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATC03_RS11995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ATC03_RS11995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ATC03_RS12000	COG0739	heme binding
ATC03_RS12030	COG2837	iron assimilation
ATC03_RS12035	COG2847	Copper chaperone PCu(A)C
ATC03_RS12050	COG0789	Transcriptional regulator
ATC03_RS12090	COG4916	TIR domain
ATC03_RS12165	COG1937	Protein conserved in bacteria
ATC03_RS12170	COG2217	Heavy metal translocating P-type atpase
ATC03_RS12180	COG2217	Heavy metal translocating P-type atpase
ATC03_RS12255	COG1388	LysM domain
ATC03_RS12255	COG4942	peptidase
ATC03_RS12345	COG1160	GTP binding
ATC03_RS12350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ATC03_RS12365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ATC03_RS12370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ATC03_RS12385	COG0494	nUDIX hydrolase
ATC03_RS12390	COG0504	CTP synthase activity
ATC03_RS12395	COG0497	DNA recombination
ATC03_RS12400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ATC03_RS12410	COG0647	UMP catabolic process
ATC03_RS12435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ATC03_RS12450	COG2094	Belongs to the DNA glycosylase MPG family
ATC03_RS12455	COG0165	Argininosuccinate lyase
ATC03_RS12460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ATC03_RS12470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ATC03_RS12475	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ATC03_RS12480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ATC03_RS12500	COG4166	transmembrane transport
ATC03_RS12505	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ATC03_RS12520	COG0072	phenylalanine-tRNA ligase activity
ATC03_RS12520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATC03_RS12525	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ATC03_RS12530	COG0765	amino acid transport
ATC03_RS12535	COG0765	amino acid transport
ATC03_RS12545	COG1126	abc transporter atp-binding protein
ATC03_RS12550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATC03_RS12555	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ATC03_RS12560	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ATC03_RS12565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ATC03_RS12580	COG1201	RNA secondary structure unwinding
ATC03_RS12595	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ATC03_RS12600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ATC03_RS12605	COG0131	Imidazoleglycerol-phosphate dehydratase
ATC03_RS12610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ATC03_RS12620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ATC03_RS12630	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ATC03_RS12635	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ATC03_RS12640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ATC03_RS12645	COG2890	protein-(glutamine-N5) methyltransferase activity
ATC03_RS12650	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ATC03_RS12655	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ATC03_RS12660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATC03_RS12670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ATC03_RS12680	COG1396	sequence-specific DNA binding
ATC03_RS12685	COG1546	Belongs to the CinA family
ATC03_RS12685	COG1058	Belongs to the CinA family
ATC03_RS12695	COG1674	ftsk spoiiie
ATC03_RS12705	COG0577	efflux transmembrane transporter activity
ATC03_RS12710	COG0577	efflux transmembrane transporter activity
ATC03_RS12710	COG1136	(ABC) transporter
ATC03_RS12720	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ATC03_RS12725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATC03_RS12740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ATC03_RS12755	COG1764	response to oxidative stress
ATC03_RS12760	COG1090	epimerase
ATC03_RS12770	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ATC03_RS12785	COG0612	Peptidase, M16
ATC03_RS12790	COG0667	Aldo Keto reductase
ATC03_RS12805	COG1960	acyl-CoA dehydrogenase activity
ATC03_RS12815	COG2226	methyltransferase
ATC03_RS12840	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ATC03_RS12855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ATC03_RS12860	COG1309	transcriptional regulator
ATC03_RS12870	COG2154	pterin-4-alpha-carbinolamine dehydratase
ATC03_RS12875	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATC03_RS12880	COG0022	dehydrogenase e1 component
ATC03_RS12910	COG2755	lipolytic protein G-D-S-L family
ATC03_RS12915	COG1185	polyribonucleotide nucleotidyltransferase activity
ATC03_RS12930	COG1131	(ABC) transporter
ATC03_RS12935	COG3559	Exporter of polyketide antibiotics
ATC03_RS12960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS12970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATC03_RS13000	COG2826	transposase and inactivated derivatives, IS30 family
ATC03_RS13025	COG1573	uracil-dna glycosylase
ATC03_RS13030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ATC03_RS13040	COG3189	MarR family transcriptional regulator
ATC03_RS13050	COG3250	beta-galactosidase activity
ATC03_RS13080	COG0545	Peptidyl-prolyl cis-trans isomerase
ATC03_RS13090	COG0277	FAD linked oxidase domain protein
ATC03_RS13100	COG2186	Transcriptional regulator
ATC03_RS13130	COG2186	Transcriptional regulator
ATC03_RS13135	COG4948	Mandelate Racemase Muconate Lactonizing
ATC03_RS13155	COG2233	PERMEase
ATC03_RS13160	COG2252	PERMEase
ATC03_RS13175	COG1051	belongs to the nudix hydrolase family
ATC03_RS13185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ATC03_RS13200	COG1937	Protein conserved in bacteria
ATC03_RS13210	COG0702	epimerase
ATC03_RS13220	COG3177	Filamentation induced by cAMP protein fic
ATC03_RS13225	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_RS13230	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_RS13235	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ATC03_RS13240	COG2390	Transcriptional regulator
ATC03_RS13245	COG1940	carbohydrate kinase activity
ATC03_RS13250	COG2807	transmembrane transport
ATC03_RS13255	COG0196	riboflavin kinase activity
ATC03_RS13270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ATC03_RS13275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ATC03_RS13295	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ATC03_RS13300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ATC03_RS13315	COG0442	prolyl-tRNA aminoacylation
ATC03_RS13335	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ATC03_RS13350	COG0183	Belongs to the thiolase family
ATC03_RS13365	COG2197	response regulator
ATC03_RS13370	COG4585	Histidine kinase
ATC03_RS13375	COG0750	zinc metalloprotease
ATC03_RS13380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ATC03_RS13390	COG0204	Acyl-transferase
ATC03_RS13390	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_RS13420	COG1176	ABC-type spermidine putrescine transport system, permease component I
ATC03_RS13425	COG3842	ATPase activity
ATC03_RS13435	COG1674	ftsk spoiiie
ATC03_RS13455	COG0714	Associated with various cellular activities
ATC03_RS13470	COG0631	protein serine/threonine phosphatase activity
ATC03_RS13485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ATC03_RS13490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATC03_RS13500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ATC03_RS13505	COG2818	Glycosylase
ATC03_RS13510	COG3022	response to hydroperoxide
ATC03_RS13520	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ATC03_RS13525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ATC03_RS13530	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ATC03_RS13535	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ATC03_RS13540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ATC03_RS13545	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ATC03_RS13550	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ATC03_RS13555	COG0356	it plays a direct role in the translocation of protons across the membrane
ATC03_RS13565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATC03_RS13590	COG2890	protein-(glutamine-N5) methyltransferase activity
ATC03_RS13600	COG1045	serine acetyltransferase
ATC03_RS13605	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ATC03_RS13615	COG0083	homoserine kinase activity
ATC03_RS13620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ATC03_RS13625	COG0460	homoserine dehydrogenase
ATC03_RS13630	COG0019	diaminopimelate decarboxylase activity
ATC03_RS13640	COG0018	arginyl-trna synthetase
ATC03_RS13650	COG1846	Transcriptional regulator
ATC03_RS13650	COG1940	carbohydrate kinase activity
ATC03_RS13660	COG1595	DNA-templated transcription, initiation
ATC03_RS13675	COG1842	Phage shock protein A
ATC03_RS13700	COG1120	ATPase activity
ATC03_RS13705	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATC03_RS13710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATC03_RS13720	COG0154	amidase activity
ATC03_RS13745	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ATC03_RS13750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ATC03_RS13770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ATC03_RS13790	COG2814	Major facilitator Superfamily
ATC03_RS13820	COG0765	amino acid transport
ATC03_RS13830	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ATC03_RS13835	COG1011	Hydrolase
ATC03_RS13840	COG1902	pentaerythritol trinitrate reductase activity
ATC03_RS13865	COG0567	Dehydrogenase, E1 component
ATC03_RS13865	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATC03_RS13870	COG2409	Drug exporters of the RND superfamily
ATC03_RS13880	COG1595	DNA-templated transcription, initiation
ATC03_RS13940	COG0653	protein targeting
ATC03_RS13945	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ATC03_RS13950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ATC03_RS13955	COG5401	PFAM Sporulation and spore germination
ATC03_RS13960	COG5002	protein histidine kinase activity
ATC03_RS13965	COG0745	RESPONSE REGULATOR receiver
ATC03_RS13985	COG0714	Associated with various cellular activities
ATC03_RS14010	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ATC03_RS14015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATC03_RS14055	COG1482	cell wall glycoprotein biosynthetic process
ATC03_RS14060	COG1960	acyl-CoA dehydrogenase activity
ATC03_RS14110	COG1216	Glycosyl transferase, family 2
ATC03_RS14130	COG1086	Polysaccharide biosynthesis protein
ATC03_RS14140	COG1216	Glycosyl transferase, family 2
ATC03_RS14155	COG1216	Glycosyl transferase, family 2
ATC03_RS14160	COG0463	Glycosyl transferase, family 2
ATC03_RS14175	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ATC03_RS14180	COG1088	dTDP-glucose 4,6-dehydratase activity
ATC03_RS14210	COG0546	phosphoglycolate phosphatase activity
ATC03_RS14210	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ATC03_RS14215	COG0297	glycogen (starch) synthase activity
ATC03_RS14225	COG0297	glycogen (starch) synthase activity
ATC03_RS14265	COG1316	TRANSCRIPTIONal
ATC03_RS14300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ATC03_RS14325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ATC03_RS14330	COG0424	maF-like protein
ATC03_RS14335	COG4770	biotin carboxylase activity
ATC03_RS14345	COG0531	amino acid
ATC03_RS14360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATC03_RS14370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATC03_RS14375	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ATC03_RS14390	COG1079	Belongs to the binding-protein-dependent transport system permease family
ATC03_RS14395	COG4603	Belongs to the binding-protein-dependent transport system permease family
ATC03_RS14400	COG3845	ABC transporter
ATC03_RS14405	COG1744	ABC transporter substrate-binding protein PnrA-like
ATC03_RS14410	COG1744	ABC transporter substrate-binding protein PnrA-like
ATC03_RS14420	COG2009	succinate dehydrogenase
ATC03_RS14435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ATC03_RS14455	COG0708	Exodeoxyribonuclease III
ATC03_RS14460	COG0180	Tryptophanyl-tRNA synthetase
ATC03_RS14475	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ATC03_RS14480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ATC03_RS14490	COG2390	Transcriptional regulator
ATC03_RS14505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ATC03_RS14505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ATC03_RS14510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ATC03_RS14520	COG0477	Major facilitator Superfamily
ATC03_RS14535	COG2313	pseudouridylate synthase activity
ATC03_RS14550	COG1132	(ABC) transporter
ATC03_RS14565	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ATC03_RS14590	COG0183	Belongs to the thiolase family
ATC03_RS14640	COG3971	2-oxopent-4-enoate hydratase activity
ATC03_RS14650	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATC03_RS14660	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_RS14675	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_RS14680	COG1309	transcriptional regulator
ATC03_RS14705	COG1335	isochorismatase
ATC03_RS14715	COG0673	inositol 2-dehydrogenase activity
ATC03_RS14735	COG1309	transcriptional regulator
ATC03_RS14740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ATC03_RS14745	COG1653	transport
ATC03_RS14750	COG0395	ABC-type sugar transport system, permease component
ATC03_RS14755	COG1175	transmembrane transport
ATC03_RS14760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATC03_RS14770	COG1414	Transcriptional regulator
ATC03_RS14790	COG0395	ABC-type sugar transport system, permease component
ATC03_RS14795	COG1175	transmembrane transport
ATC03_RS14820	COG3250	beta-galactosidase activity
ATC03_RS14835	COG1136	(ABC) transporter
ATC03_RS14835	COG0577	efflux transmembrane transporter activity
ATC03_RS14840	COG0577	efflux transmembrane transporter activity
ATC03_RS14840	COG1136	(ABC) transporter
ATC03_RS14855	COG0745	RESPONSE REGULATOR receiver
ATC03_RS14860	COG2205	protein histidine kinase activity
ATC03_RS14880	COG4948	Mandelate Racemase Muconate Lactonizing
ATC03_RS14890	COG0395	ABC-type sugar transport system, permease component
ATC03_RS14910	COG0800	Aldolase
ATC03_RS14925	COG2197	response regulator
ATC03_RS14945	COG0470	DNA polymerase III
ATC03_RS14950	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ATC03_RS14955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ATC03_RS14955	COG1754	DNA topoisomerase type I activity
ATC03_RS14995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ATC03_RS15000	COG0584	glycerophosphoryl diester phosphodiesterase
ATC03_RS15010	COG0039	L-malate dehydrogenase activity
ATC03_RS15015	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ATC03_RS15015	COG0519	Catalyzes the synthesis of GMP from XMP
ATC03_RS15025	COG1309	transcriptional regulator
ATC03_RS15040	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ATC03_RS15045	COG0516	GMP reductase activity
ATC03_RS15050	COG0488	(ABC) transporter
ATC03_RS15055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ATC03_RS15095	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ATC03_RS15120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ATC03_RS15125	COG0456	acetyltransferase
ATC03_RS15135	COG0802	atpase or kinase
ATC03_RS15140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ATC03_RS15145	COG0736	holo-[acyl-carrier-protein] synthase activity
ATC03_RS15150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATC03_RS15155	COG1072	(Pantothenic acid kinase))
ATC03_RS15160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATC03_RS15165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ATC03_RS15170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ATC03_RS15175	COG0101	tRNA pseudouridine synthase activity
ATC03_RS15180	COG0203	ribosomal protein L17
ATC03_RS15185	COG0202	RNA polymerase activity
ATC03_RS15190	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ATC03_RS15195	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ATC03_RS15200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ATC03_RS15205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ATC03_RS15210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATC03_RS15215	COG0024	Methionine aminopeptidase
ATC03_RS15220	COG0563	adenylate kinase activity
ATC03_RS15230	COG0200	Binds to the 23S rRNA
ATC03_RS15235	COG1841	ribosomal large subunit assembly
ATC03_RS15240	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ATC03_RS15245	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ATC03_RS15250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ATC03_RS15255	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ATC03_RS15260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ATC03_RS15265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ATC03_RS15270	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ATC03_RS15275	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ATC03_RS15280	COG0255	Belongs to the universal ribosomal protein uL29 family
ATC03_RS15285	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ATC03_RS15290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ATC03_RS15295	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ATC03_RS15300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ATC03_RS15305	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ATC03_RS15310	COG0089	rRNA binding
ATC03_RS15315	COG0088	Forms part of the polypeptide exit tunnel
ATC03_RS15320	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ATC03_RS15325	COG0051	transcription antitermination factor activity, RNA binding
ATC03_RS15340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ATC03_RS15345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ATC03_RS15350	COG0049	tRNA binding
ATC03_RS15355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ATC03_RS15365	COG1739	Uncharacterized protein family UPF0029
ATC03_RS15460	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ATC03_RS15485	COG1459	type II secretion system
ATC03_RS15495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ATC03_RS15500	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ATC03_RS15505	COG0085	RNA polymerase activity
ATC03_RS15525	COG1984	allophanate hydrolase subunit 2
ATC03_RS15535	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ATC03_RS15575	COG0513	Belongs to the DEAD box helicase family
ATC03_RS15635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ATC03_RS15635	COG0519	Catalyzes the synthesis of GMP from XMP
ATC03_RS15650	COG2261	transglycosylase associated protein
ATC03_RS15660	COG3938	Belongs to the proline racemase family
ATC03_RS15680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATC03_RS15685	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ATC03_RS15685	COG2066	Belongs to the glutaminase family
ATC03_RS15695	COG1802	Transcriptional regulator
ATC03_RS15700	COG0006	proline dipeptidase activity
ATC03_RS15715	COG0667	Aldo Keto reductase
ATC03_RS15745	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ATC03_RS15760	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ATC03_RS15780	COG3655	Transcriptional regulator
ATC03_RS15810	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ATC03_RS15815	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ATC03_RS15840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ATC03_RS15845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ATC03_RS15850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ATC03_RS15855	COG0302	gtp cyclohydrolase
ATC03_RS15860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ATC03_RS15865	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ATC03_RS15870	COG0037	tRNA processing
ATC03_RS15875	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ATC03_RS15885	COG0741	lytic transglycosylase activity
ATC03_RS15885	COG1196	nuclear chromosome segregation
ATC03_RS15885	COG0739	heme binding
ATC03_RS15905	COG0438	transferase activity, transferring glycosyl groups
ATC03_RS15910	COG0438	transferase activity, transferring glycosyl groups
ATC03_RS15930	COG2197	response regulator
ATC03_RS15935	COG3850	Histidine kinase
ATC03_RS15945	COG0534	Mate efflux family protein
ATC03_RS15985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ATC03_RS15985	COG1796	DNA polymerase
ATC03_RS15995	COG0697	spore germination
ATC03_RS16000	COG0596	Alpha beta hydrolase
ATC03_RS16015	COG0039	L-malate dehydrogenase activity
ATC03_RS16055	COG1609	Transcriptional regulator
ATC03_RS16070	COG0395	ABC-type sugar transport system, permease component
ATC03_RS16075	COG1175	transmembrane transport
ATC03_RS16090	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ATC03_RS16105	COG0514	ATP-dependent DNA helicase (RecQ)
ATC03_RS16125	COG1525	nuclease
ATC03_RS16125	COG0737	Belongs to the 5'-nucleotidase family
ATC03_RS16125	COG4085	toxin activity
ATC03_RS16135	COG4581	dead DEAH box helicase
ATC03_RS16145	COG3265	gluconokinase activity
ATC03_RS16150	COG0738	Major facilitator superfamily
ATC03_RS16160	COG0667	Aldo Keto reductase
ATC03_RS16170	COG0384	phenazine biosynthesis protein PhzF
ATC03_RS16185	COG0640	Transcriptional regulator
ATC03_RS16195	COG1846	Transcriptional regulator
ATC03_RS16200	COG2814	Major facilitator Superfamily
ATC03_RS16205	COG0656	L-ascorbic acid biosynthetic process
ATC03_RS16210	COG0693	protein deglycase activity
ATC03_RS16220	COG1278	Cold shock
ATC03_RS16245	COG0277	FAD linked oxidase domain protein
ATC03_RS16260	COG1278	Cold shock
ATC03_RS16270	COG0730	response to heat
ATC03_RS16300	COG1309	transcriptional regulator
ATC03_RS16340	COG0183	Belongs to the thiolase family
ATC03_RS16345	COG1960	acyl-CoA dehydrogenase activity
ATC03_RS16370	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_RS16430	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS16440	COG1404	Belongs to the peptidase S8 family
ATC03_RS16450	COG1250	3-hydroxyacyl-CoA dehydrogenase
ATC03_RS16465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ATC03_RS16485	COG1349	DNA-binding transcription factor activity
ATC03_RS16545	COG2873	o-acetylhomoserine
ATC03_RS16565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ATC03_RS16595	COG4221	oxidoreductase activity
ATC03_RS16620	COG3401	FG-GAP repeat protein
ATC03_RS16640	COG1715	Restriction endonuclease
ATC03_RS16745	COG3795	YCII-related domain
ATC03_RS16785	COG1196	nuclear chromosome segregation
ATC03_RS16785	COG0741	lytic transglycosylase activity
ATC03_RS16785	COG0739	heme binding
ATC03_RS16795	COG2326	polyphosphate kinase activity
ATC03_RS16805	COG1733	regulation of RNA biosynthetic process
ATC03_RS16810	COG0702	epimerase
ATC03_RS16870	COG0740	serine-type endopeptidase activity
ATC03_RS16875	COG0740	serine-type endopeptidase activity
ATC03_RS16890	COG0477	Major facilitator Superfamily
ATC03_RS16920	COG1737	Transcriptional regulator
ATC03_RS16930	COG0395	ABC-type sugar transport system, permease component
ATC03_RS16935	COG1175	transmembrane transport
ATC03_RS16940	COG4977	sequence-specific DNA binding
ATC03_RS16945	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ATC03_RS16950	COG0352	thiamine-phosphate diphosphorylase activity
ATC03_RS16955	COG0351	phosphomethylpyrimidine kinase
ATC03_RS16955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ATC03_RS16955	COG0352	thiamine-phosphate diphosphorylase activity
ATC03_RS16960	COG1305	Transglutaminase-like
ATC03_RS16965	COG0702	epimerase
ATC03_RS16975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ATC03_RS17000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ATC03_RS17010	COG0154	amidase activity
ATC03_RS17015	COG2957	Belongs to the agmatine deiminase family
ATC03_RS17040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS17065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS17080	COG1122	ATPase activity
ATC03_RS17085	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ATC03_RS17115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ATC03_RS17115	COG2111	Na H antiporter
ATC03_RS17120	COG1006	Multisubunit Na H antiporter MnhC subunit
ATC03_RS17125	COG0651	ATP synthesis coupled electron transport
ATC03_RS17140	COG1320	monovalent cation:proton antiporter activity
ATC03_RS17215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ATC03_RS17220	COG2151	metal-sulfur cluster biosynthetic enzyme
ATC03_RS17225	COG3396	Phenylacetate-CoA oxygenase
ATC03_RS17230	COG3460	Phenylacetate-CoA oxygenase
ATC03_RS17235	COG3396	Phenylacetate-CoA oxygenase
ATC03_RS17250	COG1309	transcriptional regulator
ATC03_RS17255	COG0514	ATP-dependent DNA helicase (RecQ)
ATC03_RS17260	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_RS17260	COG2030	dehydratase
ATC03_RS17265	COG1250	3-hydroxyacyl-CoA dehydrogenase
ATC03_RS17270	COG1024	Enoyl-CoA hydratase
ATC03_RS17320	COG0513	Belongs to the DEAD box helicase family
ATC03_RS17325	COG0657	acetylesterase activity
ATC03_RS17380	COG1595	DNA-templated transcription, initiation
ATC03_RS17405	COG0586	Pfam SNARE associated Golgi protein
ATC03_RS17440	COG2986	histidine ammonia-lyase
ATC03_RS17445	COG1196	nuclear chromosome segregation
ATC03_RS17445	COG0741	lytic transglycosylase activity
ATC03_RS17445	COG0739	heme binding
ATC03_RS17450	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ATC03_RS17455	COG1228	amidohydrolase
ATC03_RS17470	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ATC03_RS17505	COG0521	Mo-molybdopterin cofactor biosynthetic process
ATC03_RS17505	COG0315	cyclic pyranopterin monophosphate synthase activity
ATC03_RS17515	COG2409	Drug exporters of the RND superfamily
ATC03_RS17520	COG1309	transcriptional regulator
ATC03_RS17555	COG0010	Belongs to the arginase family
ATC03_RS17565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ATC03_RS17605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ATC03_RS17650	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ATC03_RS17655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ATC03_RS17660	COG0531	amino acid
ATC03_RS17680	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ATC03_RS17695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATC03_RS17700	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ATC03_RS17720	COG4558	Periplasmic binding protein
ATC03_RS17725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATC03_RS17730	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ATC03_RS17755	COG0151	Belongs to the GarS family
ATC03_RS17760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ATC03_RS17770	COG2514	catechol 2,3-dioxygenase activity
ATC03_RS17780	COG3483	tryptophan 2,3-dioxygenase activity
ATC03_RS17805	COG1695	Transcriptional regulator
ATC03_RS17810	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ATC03_RS17815	COG0047	phosphoribosylformylglycinamidine synthase activity
ATC03_RS17825	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_RS17835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ATC03_RS17845	COG2814	Major facilitator Superfamily
ATC03_RS17850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ATC03_RS17875	COG1063	alcohol dehydrogenase
ATC03_RS17885	COG0300	oxidoreductase activity
ATC03_RS17890	COG0287	Prephenate dehydrogenase
ATC03_RS17890	COG1605	Chorismate mutase
ATC03_RS17900	COG0577	efflux transmembrane transporter activity
ATC03_RS17900	COG1136	(ABC) transporter
ATC03_RS17905	COG3397	chitin binding
ATC03_RS17915	COG1131	(ABC) transporter
ATC03_RS17920	COG1725	Transcriptional regulator
ATC03_RS17935	COG0697	spore germination
ATC03_RS17940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATC03_RS17965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ATC03_RS17975	COG3275	phosphorelay sensor kinase activity
ATC03_RS17990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ATC03_RS18010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ATC03_RS18025	COG0137	argininosuccinate synthase activity
ATC03_RS18035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATC03_RS18080	COG0142	geranyltranstransferase activity
ATC03_RS18090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ATC03_RS18125	COG4251	negative regulation of phosphorylation
ATC03_RS18140	COG2202	Pas domain
ATC03_RS18140	COG2199	diguanylate cyclase activity
ATC03_RS18140	COG2200	EAL domain
ATC03_RS18155	COG0515	serine threonine protein kinase
ATC03_RS18155	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATC03_RS18255	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ATC03_RS18290	COG3119	arylsulfatase activity
ATC03_RS18305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ATC03_RS18310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ATC03_RS18315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ATC03_RS18320	COG1116	anion transmembrane transporter activity
ATC03_RS18320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ATC03_RS18325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ATC03_RS18335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATC03_RS18350	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ATC03_RS18360	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ATC03_RS18390	COG1063	alcohol dehydrogenase
ATC03_RS18400	COG0346	lactoylglutathione lyase activity
ATC03_RS18405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ATC03_RS18410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ATC03_RS18420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS18425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATC03_RS18440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATC03_RS18445	COG1120	ATPase activity
ATC03_RS18480	COG0405	Gamma-glutamyltransferase
ATC03_RS18495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS18500	COG1920	GTP binding
ATC03_RS18505	COG0778	Nitroreductase
ATC03_RS18505	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
ATC03_RS18510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS18520	COG0778	Nitroreductase
ATC03_RS18520	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
ATC03_RS18550	COG0300	oxidoreductase activity
ATC03_RS18560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ATC03_RS18565	COG2271	Major facilitator Superfamily
ATC03_RS18575	COG1116	anion transmembrane transporter activity
ATC03_RS18585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ATC03_RS18590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ATC03_RS18605	COG1309	transcriptional regulator
ATC03_RS18650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ATC03_RS18660	COG0277	FAD linked oxidase domain protein
ATC03_RS18670	COG4585	Histidine kinase
ATC03_RS18675	COG2197	response regulator
ATC03_RS18680	COG2226	methyltransferase
ATC03_RS18685	COG0640	Transcriptional regulator
ATC03_RS18705	COG4152	abc transporter atp-binding protein
ATC03_RS18735	COG1309	transcriptional regulator
ATC03_RS18785	COG2272	Belongs to the type-B carboxylesterase lipase family
ATC03_RS18790	COG0477	Major facilitator Superfamily
ATC03_RS18800	COG4941	Belongs to the sigma-70 factor family
ATC03_RS18810	COG0542	response to heat
ATC03_RS18815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_RS18850	COG0596	Alpha beta hydrolase
ATC03_RS18865	COG3424	synthase
ATC03_RS18880	COG0628	permease
ATC03_RS18900	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ATC03_RS18920	COG0789	Transcriptional regulator
ATC03_RS18925	COG0484	heat shock protein binding
ATC03_RS18930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ATC03_RS18935	COG0443	Heat shock 70 kDa protein
ATC03_RS18950	COG0477	Major facilitator Superfamily
ATC03_RS18995	COG4608	Belongs to the ABC transporter superfamily
ATC03_RS19000	COG0601	transmembrane transport
ATC03_RS19005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATC03_RS19010	COG0444	Belongs to the ABC transporter superfamily
ATC03_RS19020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ATC03_RS19040	COG1648	precorrin-2 dehydrogenase activity
ATC03_RS19040	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ATC03_RS19065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATC03_RS19070	COG1280	lysine exporter protein (LysE YggA)
ATC03_RS19080	COG1063	alcohol dehydrogenase
ATC03_RS19100	COG1177	transmembrane transport
ATC03_RS19105	COG1176	ABC-type spermidine putrescine transport system, permease component I
ATC03_RS19110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ATC03_RS19115	COG3842	ATPase activity
ATC03_RS19140	COG2267	carboxylic ester hydrolase activity
ATC03_RS19155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATC03_RS19165	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ATC03_RS19185	COG0717	Belongs to the dCTP deaminase family
ATC03_RS19210	COG1595	DNA-templated transcription, initiation
ATC03_RS19220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ATC03_RS19250	COG0739	heme binding
ATC03_RS19260	COG1063	alcohol dehydrogenase
ATC03_RS19265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ATC03_RS19270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ATC03_RS19275	COG3639	organic phosphonate transmembrane transporter activity
ATC03_RS19280	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ATC03_RS19285	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ATC03_RS19300	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ATC03_RS19315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ATC03_RS19320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ATC03_RS19330	COG3336	cytochrome c oxidase
ATC03_RS19335	COG0776	regulation of translation
ATC03_RS19340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ATC03_RS19345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ATC03_RS19350	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ATC03_RS19370	COG0517	IMP dehydrogenase activity
ATC03_RS19370	COG4175	Glycine betaine
ATC03_RS19380	COG0076	glutamate decarboxylase activity
ATC03_RS19390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ATC03_RS19395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ATC03_RS19400	COG1121	(ABC) transporter
ATC03_RS19415	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATC03_RS19420	COG0022	dehydrogenase e1 component
ATC03_RS19430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ATC03_RS19435	COG1950	PFAM Membrane protein of
ATC03_RS19455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATC03_RS19460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ATC03_RS19475	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ATC03_RS19480	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ATC03_RS19485	COG1414	Transcriptional regulator
ATC03_RS19510	COG0656	L-ascorbic acid biosynthetic process
ATC03_RS19520	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_RS19535	COG0534	Mate efflux family protein
ATC03_RS19550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ATC03_RS19555	COG0765	amino acid transport
ATC03_RS19575	COG0305	Participates in initiation and elongation during chromosome replication
ATC03_RS19580	COG0359	binds to the 23S rRNA
ATC03_RS19585	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ATC03_RS19595	COG0360	Binds together with S18 to 16S ribosomal RNA
ATC03_RS19600	COG0617	tRNA 3'-terminal CCA addition
ATC03_RS19615	COG0492	ferredoxin-NADP+ reductase activity
ATC03_RS19620	COG3118	belongs to the thioredoxin family
ATC03_RS19625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATC03_RS19630	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATC03_RS19640	COG1192	Involved in chromosome partitioning
ATC03_RS19650	COG0357	Ribosomal RNA small subunit methyltransferase G
ATC03_RS19660	COG0706	membrane insertase activity
ATC03_RS19665	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ATC03_RS19670	COG0594	ribonuclease P activity
ATC03_RS19675	COG0230	Belongs to the bacterial ribosomal protein bL34 family