locus-tag	class	description
MTP13_RS00005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS00010	COG0673	inositol 2-dehydrogenase activity
MTP13_RS00025	COG0456	acetyltransferase
MTP13_RS00040	COG4948	Mandelate Racemase Muconate Lactonizing
MTP13_RS00070	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MTP13_RS00080	COG3960	tartronate-semialdehyde synthase activity
MTP13_RS00085	COG2084	Dehydrogenase
MTP13_RS00090	COG3622	Belongs to the hyi family
MTP13_RS00100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTP13_RS00110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MTP13_RS00115	COG1012	belongs to the aldehyde dehydrogenase family
MTP13_RS00120	COG1228	amidohydrolase
MTP13_RS00130	COG1129	ABC transporter
MTP13_RS00135	COG1879	ABC-type sugar transport system periplasmic component
MTP13_RS00160	COG3257	ureidoglycine aminohydrolase activity
MTP13_RS00170	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MTP13_RS00175	COG1414	Transcriptional regulator
MTP13_RS00185	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MTP13_RS00205	COG2252	PERMEase
MTP13_RS00210	COG0590	tRNA wobble adenosine to inosine editing
MTP13_RS00235	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MTP13_RS00260	COG0315	cyclic pyranopterin monophosphate synthase activity
MTP13_RS00265	COG0521	Mo-molybdopterin cofactor biosynthetic process
MTP13_RS00265	COG0315	cyclic pyranopterin monophosphate synthase activity
MTP13_RS00275	COG2814	Major facilitator Superfamily
MTP13_RS00280	COG4552	Acetyltransferase involved in intracellular survival and related
MTP13_RS00290	COG0477	Major facilitator Superfamily
MTP13_RS00305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTP13_RS00325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MTP13_RS00325	COG1796	DNA polymerase
MTP13_RS00335	COG0702	epimerase
MTP13_RS00340	COG1051	belongs to the nudix hydrolase family
MTP13_RS00345	COG0626	cystathionine gamma-synthase activity
MTP13_RS00380	COG1793	dna ligase
MTP13_RS00390	COG1473	amidohydrolase
MTP13_RS00410	COG1595	DNA-templated transcription, initiation
MTP13_RS00415	COG0488	(ABC) transporter
MTP13_RS00420	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MTP13_RS00440	COG1396	sequence-specific DNA binding
MTP13_RS00480	COG1120	ATPase activity
MTP13_RS00485	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP13_RS00490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP13_RS00515	COG1132	(ABC) transporter
MTP13_RS00520	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MTP13_RS00520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTP13_RS00525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MTP13_RS00530	COG1609	Transcriptional regulator
MTP13_RS00555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP13_RS00560	COG4172	Belongs to the ABC transporter superfamily
MTP13_RS00570	COG1940	carbohydrate kinase activity
MTP13_RS00585	COG0494	nUDIX hydrolase
MTP13_RS00615	COG3152	Membrane
MTP13_RS00625	COG0154	amidase activity
MTP13_RS00655	COG0542	response to heat
MTP13_RS00675	COG0537	adenosine 5'-monophosphoramidase activity
MTP13_RS00700	COG0488	(ABC) transporter
MTP13_RS00770	COG0477	Major facilitator Superfamily
MTP13_RS00775	COG1234	tRNA 3'-trailer cleavage
MTP13_RS00780	COG0583	DNA-binding transcription factor activity
MTP13_RS00805	COG0395	ABC-type sugar transport system, permease component
MTP13_RS00810	COG1175	transmembrane transport
MTP13_RS00820	COG1609	Transcriptional regulator
MTP13_RS00845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MTP13_RS00845	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MTP13_RS00865	COG0251	oxidation-reduction process
MTP13_RS00920	COG1982	Orn Lys Arg decarboxylase major
MTP13_RS00960	COG3842	ATPase activity
MTP13_RS01025	COG2188	Transcriptional regulator
MTP13_RS01035	COG0477	Major facilitator Superfamily
MTP13_RS01040	COG0477	Major facilitator Superfamily
MTP13_RS01050	COG2814	Major facilitator Superfamily
MTP13_RS01055	COG2390	Transcriptional regulator
MTP13_RS01060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MTP13_RS01065	COG1070	Carbohydrate kinase
MTP13_RS01085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MTP13_RS01140	COG1609	Transcriptional regulator
MTP13_RS01145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MTP13_RS01150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MTP13_RS01155	COG1780	Probably involved in ribonucleotide reductase function
MTP13_RS01170	COG2197	response regulator
MTP13_RS01175	COG4585	Histidine kinase
MTP13_RS01195	COG1172	Belongs to the binding-protein-dependent transport system permease family
MTP13_RS01230	COG0531	amino acid
MTP13_RS01245	COG0477	Major facilitator Superfamily
MTP13_RS01260	COG1132	(ABC) transporter
MTP13_RS01265	COG0395	ABC-type sugar transport system, permease component
MTP13_RS01270	COG1175	transmembrane transport
MTP13_RS01275	COG1653	transport
MTP13_RS01285	COG2814	Major facilitator Superfamily
MTP13_RS01295	COG2186	Transcriptional regulator
MTP13_RS01305	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
MTP13_RS01315	COG0222	ribosome binding
MTP13_RS01320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MTP13_RS01325	COG0477	Major facilitator Superfamily
MTP13_RS01335	COG2205	protein histidine kinase activity
MTP13_RS01340	COG0745	RESPONSE REGULATOR receiver
MTP13_RS01355	COG0577	efflux transmembrane transporter activity
MTP13_RS01355	COG1136	(ABC) transporter
MTP13_RS01375	COG4211	Belongs to the binding-protein-dependent transport system permease family
MTP13_RS01380	COG1172	Belongs to the binding-protein-dependent transport system permease family
MTP13_RS01385	COG1129	ABC transporter
MTP13_RS01390	COG0673	inositol 2-dehydrogenase activity
MTP13_RS01400	COG1609	Transcriptional regulator
MTP13_RS01410	COG3119	arylsulfatase activity
MTP13_RS01415	COG0477	Major facilitator Superfamily
MTP13_RS01435	COG0640	Transcriptional regulator
MTP13_RS01450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MTP13_RS01460	COG3842	ATPase activity
MTP13_RS01475	COG1177	transmembrane transport
MTP13_RS01480	COG1228	amidohydrolase
MTP13_RS01500	COG1733	regulation of RNA biosynthetic process
MTP13_RS01510	COG1335	isochorismatase
MTP13_RS01520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTP13_RS01530	COG1012	belongs to the aldehyde dehydrogenase family
MTP13_RS01535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MTP13_RS01545	COG0531	amino acid
MTP13_RS01565	COG1733	regulation of RNA biosynthetic process
MTP13_RS01600	COG1126	abc transporter atp-binding protein
MTP13_RS01605	COG0765	amino acid transport
MTP13_RS01610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTP13_RS01645	COG1012	belongs to the aldehyde dehydrogenase family
MTP13_RS01655	COG0800	Aldolase
MTP13_RS01670	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MTP13_RS01675	COG1414	Transcriptional regulator
MTP13_RS01690	COG1254	Belongs to the acylphosphatase family
MTP13_RS01695	COG0081	regulation of translation
MTP13_RS01700	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MTP13_RS01720	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MTP13_RS01725	COG0436	Aminotransferase
MTP13_RS01730	COG0583	DNA-binding transcription factor activity
MTP13_RS01755	COG4585	Histidine kinase
MTP13_RS01760	COG2197	response regulator
MTP13_RS01765	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MTP13_RS01770	COG2197	response regulator
MTP13_RS01800	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MTP13_RS01810	COG2030	dehydratase
MTP13_RS01820	COG1309	transcriptional regulator
MTP13_RS01830	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MTP13_RS01855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MTP13_RS01875	COG3842	ATPase activity
MTP13_RS01895	COG0583	DNA-binding transcription factor activity
MTP13_RS01910	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MTP13_RS01915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MTP13_RS01930	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
MTP13_RS01950	COG2723	6-phospho-beta-galactosidase activity
MTP13_RS01970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MTP13_RS01975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS01990	COG0438	transferase activity, transferring glycosyl groups
MTP13_RS02030	COG0366	Alpha amylase catalytic
MTP13_RS02060	COG1609	Transcriptional regulator
MTP13_RS02075	COG3191	aminopeptidase activity
MTP13_RS02085	COG0444	Belongs to the ABC transporter superfamily
MTP13_RS02095	COG0601	transmembrane transport
MTP13_RS02105	COG1017	nitric oxide dioxygenase activity
MTP13_RS02105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MTP13_RS02110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MTP13_RS02135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MTP13_RS02190	COG1666	GTP binding
MTP13_RS02210	COG0142	geranyltranstransferase activity
MTP13_RS02215	COG2226	methyltransferase
MTP13_RS02220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MTP13_RS02225	COG2326	polyphosphate kinase activity
MTP13_RS02250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTP13_RS02265	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MTP13_RS02295	COG4948	Mandelate Racemase Muconate Lactonizing
MTP13_RS02300	COG0789	Transcriptional regulator
MTP13_RS02310	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MTP13_RS02315	COG1333	cytochrome c biogenesis protein
MTP13_RS02320	COG0785	Cytochrome C biogenesis protein
MTP13_RS02330	COG0406	alpha-ribazole phosphatase activity
MTP13_RS02335	COG0017	Asparaginyl-tRNA synthetase
MTP13_RS02340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MTP13_RS02380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MTP13_RS02385	COG0569	domain protein
MTP13_RS02390	COG1131	(ABC) transporter
MTP13_RS02395	COG3559	Exporter of polyketide antibiotics
MTP13_RS02415	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MTP13_RS02420	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MTP13_RS02425	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MTP13_RS02455	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MTP13_RS02490	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS02505	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MTP13_RS02565	COG0395	ABC-type sugar transport system, permease component
MTP13_RS02570	COG4209	transmembrane transport
MTP13_RS02575	COG1653	transport
MTP13_RS02580	COG0366	Alpha amylase catalytic
MTP13_RS02585	COG1609	Transcriptional regulator
MTP13_RS02615	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MTP13_RS02630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP13_RS02640	COG4166	transmembrane transport
MTP13_RS02670	COG1609	Transcriptional regulator
MTP13_RS02695	COG2188	Transcriptional regulator
MTP13_RS02720	COG0395	ABC-type sugar transport system, permease component
MTP13_RS02725	COG1175	transmembrane transport
MTP13_RS02735	COG0813	purine-nucleoside phosphorylase activity
MTP13_RS02750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MTP13_RS02765	COG3119	arylsulfatase activity
MTP13_RS02770	COG2807	transmembrane transport
MTP13_RS02790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MTP13_RS02795	COG1215	transferase activity, transferring glycosyl groups
MTP13_RS02805	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MTP13_RS02840	COG1573	uracil-dna glycosylase
MTP13_RS02845	COG3119	arylsulfatase activity
MTP13_RS02850	COG3119	arylsulfatase activity
MTP13_RS02870	COG1940	carbohydrate kinase activity
MTP13_RS02875	COG0477	Major facilitator Superfamily
MTP13_RS02880	COG1733	regulation of RNA biosynthetic process
MTP13_RS02885	COG2226	methyltransferase
MTP13_RS02890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTP13_RS02895	COG3708	Transcriptional regulator
MTP13_RS02895	COG2207	Transcriptional regulator
MTP13_RS02920	COG0604	alcohol dehydrogenase
MTP13_RS02925	COG0477	Major facilitator Superfamily
MTP13_RS02940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MTP13_RS02950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTP13_RS02955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MTP13_RS02970	COG1309	transcriptional regulator
MTP13_RS03015	COG2200	EAL domain
MTP13_RS03015	COG2202	Pas domain
MTP13_RS03015	COG2199	diguanylate cyclase activity
MTP13_RS03030	COG4251	negative regulation of phosphorylation
MTP13_RS03050	COG1309	transcriptional regulator
MTP13_RS03060	COG1609	Transcriptional regulator
MTP13_RS03065	COG0698	ribose 5-phosphate isomerase
MTP13_RS03070	COG0477	Major facilitator Superfamily
MTP13_RS03075	COG4989	oxidoreductase activity
MTP13_RS03090	COG3833	ABC-type maltose transport systems, permease component
MTP13_RS03100	COG2182	Extracellular solute-binding protein
MTP13_RS03110	COG2197	response regulator
MTP13_RS03125	COG0366	Alpha amylase catalytic
MTP13_RS03130	COG0366	Alpha amylase catalytic
MTP13_RS03145	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS03150	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MTP13_RS03205	COG1316	TRANSCRIPTIONal
MTP13_RS03215	COG1316	TRANSCRIPTIONal
MTP13_RS03220	COG0561	phosphatase activity
MTP13_RS03225	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MTP13_RS03230	COG1597	lipid kinase activity
MTP13_RS03240	COG0077	Prephenate dehydratase
MTP13_RS03245	COG2733	membrane
MTP13_RS03260	COG1876	peptidase activity
MTP13_RS03265	COG2723	6-phospho-beta-galactosidase activity
MTP13_RS03280	COG1609	Transcriptional regulator
MTP13_RS03285	COG1744	ABC transporter substrate-binding protein PnrA-like
MTP13_RS03295	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MTP13_RS03305	COG1228	amidohydrolase
MTP13_RS03325	COG0095	Lipoate-protein ligase
MTP13_RS03355	COG2814	Major facilitator Superfamily
MTP13_RS03360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MTP13_RS03370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MTP13_RS03390	COG0667	Aldo Keto reductase
MTP13_RS03400	COG2188	Transcriptional regulator
MTP13_RS03415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MTP13_RS03440	COG1472	Belongs to the glycosyl hydrolase 3 family
MTP13_RS03450	COG2211	Major facilitator Superfamily
MTP13_RS03455	COG1309	transcriptional regulator
MTP13_RS03460	COG1940	carbohydrate kinase activity
MTP13_RS03480	COG0477	Major facilitator Superfamily
MTP13_RS03490	COG0463	Glycosyl transferase, family 2
MTP13_RS03495	COG3104	oligopeptide transport
MTP13_RS03505	COG0395	ABC-type sugar transport system, permease component
MTP13_RS03515	COG1653	transport
MTP13_RS03545	COG0531	amino acid
MTP13_RS03565	COG1725	Transcriptional regulator
MTP13_RS03575	COG0189	ligase activity
MTP13_RS03575	COG0569	domain protein
MTP13_RS03580	COG0189	ligase activity
MTP13_RS03580	COG4067	protein conserved in archaea
MTP13_RS03585	COG1012	belongs to the aldehyde dehydrogenase family
MTP13_RS03600	COG1309	transcriptional regulator
MTP13_RS03635	COG0640	Transcriptional regulator
MTP13_RS03655	COG0477	Major facilitator Superfamily
MTP13_RS03660	COG1309	transcriptional regulator
MTP13_RS03675	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MTP13_RS03680	COG2079	MmgE PrpD family protein
MTP13_RS03695	COG0822	iron-sulfur transferase activity
MTP13_RS03700	COG1024	Enoyl-CoA hydratase
MTP13_RS03705	COG1280	lysine exporter protein (LysE YggA)
MTP13_RS03755	COG1131	(ABC) transporter
MTP13_RS03770	COG0631	protein serine/threonine phosphatase activity
MTP13_RS03775	COG1716	ATPase activity
MTP13_RS03790	COG0714	Associated with various cellular activities
MTP13_RS03810	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MTP13_RS03815	COG0113	porphobilinogen synthase activity
MTP13_RS03825	COG1136	(ABC) transporter
MTP13_RS03850	COG0181	hydroxymethylbilane synthase activity
MTP13_RS03855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MTP13_RS03860	COG3253	May function as heme-dependent peroxidase
MTP13_RS03875	COG0142	geranyltranstransferase activity
MTP13_RS03935	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MTP13_RS03945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MTP13_RS03950	COG0519	Catalyzes the synthesis of GMP from XMP
MTP13_RS03960	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MTP13_RS03965	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MTP13_RS03970	COG0423	glycine-tRNA ligase activity
MTP13_RS04000	COG3590	peptidase
MTP13_RS04005	COG3304	Inner membrane component domain
MTP13_RS04010	COG0534	Mate efflux family protein
MTP13_RS04020	COG0156	8-amino-7-oxononanoate synthase activity
MTP13_RS04025	COG1063	alcohol dehydrogenase
MTP13_RS04030	COG0738	Major facilitator superfamily
MTP13_RS04035	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MTP13_RS04045	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MTP13_RS04070	COG0386	Belongs to the glutathione peroxidase family
MTP13_RS04090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTP13_RS04105	COG2837	iron assimilation
MTP13_RS04145	COG1846	Transcriptional regulator
MTP13_RS04155	COG1864	DNA RNA non-specific endonuclease
MTP13_RS04155	COG3591	Belongs to the peptidase S1B family
MTP13_RS04170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MTP13_RS04175	COG1316	TRANSCRIPTIONal
MTP13_RS04180	COG2855	membrane
MTP13_RS04185	COG0583	DNA-binding transcription factor activity
MTP13_RS04195	COG1511	domain protein
MTP13_RS04200	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MTP13_RS04215	COG1733	regulation of RNA biosynthetic process
MTP13_RS04235	COG1136	(ABC) transporter
MTP13_RS04250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MTP13_RS04260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MTP13_RS04275	COG2272	Belongs to the type-B carboxylesterase lipase family
MTP13_RS04290	COG0745	RESPONSE REGULATOR receiver
MTP13_RS04310	COG2814	Major facilitator Superfamily
MTP13_RS04320	COG1595	DNA-templated transcription, initiation
MTP13_RS04335	COG4716	Myosin-crossreactive antigen
MTP13_RS04340	COG1609	Transcriptional regulator
MTP13_RS04350	COG3250	beta-galactosidase activity
MTP13_RS04365	COG0277	FAD linked oxidase domain protein
MTP13_RS04430	COG1733	regulation of RNA biosynthetic process
MTP13_RS04460	COG0657	acetylesterase activity
MTP13_RS04465	COG1172	Belongs to the binding-protein-dependent transport system permease family
MTP13_RS04470	COG1129	ABC transporter
MTP13_RS04475	COG1879	ABC-type sugar transport system periplasmic component
MTP13_RS04480	COG1940	carbohydrate kinase activity
MTP13_RS04485	COG1082	Xylose isomerase domain protein TIM barrel
MTP13_RS04490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MTP13_RS04495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MTP13_RS04525	COG1716	ATPase activity
MTP13_RS04530	COG1716	ATPase activity
MTP13_RS04545	COG0768	penicillin binding
MTP13_RS04550	COG0515	serine threonine protein kinase
MTP13_RS04555	COG0515	serine threonine protein kinase
MTP13_RS04555	COG2815	serine threonine protein kinase
MTP13_RS04570	COG3764	Sortase (surface protein transpeptidase)
MTP13_RS04580	COG0705	Rhomboid family
MTP13_RS04580	COG0457	Tetratricopeptide repeat
MTP13_RS04610	COG2814	Major facilitator Superfamily
MTP13_RS04635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MTP13_RS04640	COG0187	DNA topoisomerase II activity
MTP13_RS04645	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MTP13_RS04650	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MTP13_RS04655	COG0592	DNA-directed DNA polymerase activity
MTP13_RS04660	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MTP13_RS04665	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MTP13_RS04670	COG0594	ribonuclease P activity
MTP13_RS04680	COG0706	membrane insertase activity
MTP13_RS04690	COG0357	Ribosomal RNA small subunit methyltransferase G
MTP13_RS04695	COG1192	Involved in chromosome partitioning
MTP13_RS04705	COG1181	Belongs to the D-alanine--D-alanine ligase family
MTP13_RS04710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTP13_RS04715	COG3118	belongs to the thioredoxin family
MTP13_RS04720	COG0492	ferredoxin-NADP+ reductase activity
MTP13_RS04735	COG0617	tRNA 3'-terminal CCA addition
MTP13_RS04740	COG0360	Binds together with S18 to 16S ribosomal RNA
MTP13_RS04750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MTP13_RS04755	COG0359	binds to the 23S rRNA
MTP13_RS04760	COG0305	Participates in initiation and elongation during chromosome replication
MTP13_RS04765	COG0534	Mate efflux family protein
MTP13_RS04775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MTP13_RS04780	COG1070	Carbohydrate kinase
MTP13_RS04800	COG1175	transmembrane transport
MTP13_RS04805	COG0395	ABC-type sugar transport system, permease component
MTP13_RS04820	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MTP13_RS04825	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MTP13_RS04845	COG1176	ABC-type spermidine putrescine transport system, permease component I
MTP13_RS04850	COG1177	transmembrane transport
MTP13_RS04855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MTP13_RS04860	COG3842	ATPase activity
MTP13_RS04870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MTP13_RS04885	COG1522	sequence-specific DNA binding
MTP13_RS04895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MTP13_RS04900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MTP13_RS04920	COG1950	PFAM Membrane protein of
MTP13_RS04925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MTP13_RS04935	COG0022	dehydrogenase e1 component
MTP13_RS04940	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTP13_RS04960	COG1121	(ABC) transporter
MTP13_RS04995	COG0076	glutamate decarboxylase activity
MTP13_RS05000	COG0531	amino acid
MTP13_RS05005	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MTP13_RS05010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MTP13_RS05015	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MTP13_RS05020	COG0776	regulation of translation
MTP13_RS05035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MTP13_RS05060	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS05085	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS05095	COG1473	amidohydrolase
MTP13_RS05100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MTP13_RS05105	COG0022	dehydrogenase e1 component
MTP13_RS05135	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MTP13_RS05145	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS05150	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MTP13_RS05155	COG0251	oxidation-reduction process
MTP13_RS05165	COG0179	Fumarylacetoacetate (FAA) hydrolase
MTP13_RS05170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTP13_RS05175	COG3237	CsbD-like
MTP13_RS05185	COG2837	iron assimilation
MTP13_RS05190	COG2847	Copper chaperone PCu(A)C
MTP13_RS05195	COG2372	response to copper ion
MTP13_RS05195	COG1276	copper resistance
MTP13_RS05220	COG1136	(ABC) transporter
MTP13_RS05280	COG1070	Carbohydrate kinase
MTP13_RS05285	COG3347	Dehydrogenase
MTP13_RS05285	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS05300	COG1609	Transcriptional regulator
MTP13_RS05305	COG1129	ABC transporter
MTP13_RS05315	COG1172	Belongs to the binding-protein-dependent transport system permease family
MTP13_RS05320	COG1879	ABC-type sugar transport system periplasmic component
MTP13_RS05330	COG0667	Aldo Keto reductase
MTP13_RS05345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTP13_RS05365	COG0717	Belongs to the dCTP deaminase family
MTP13_RS05420	COG0730	response to heat
MTP13_RS05435	COG0006	proline dipeptidase activity
MTP13_RS05445	COG0601	transmembrane transport
MTP13_RS05450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP13_RS05460	COG4608	Belongs to the ABC transporter superfamily
MTP13_RS05500	COG1012	belongs to the aldehyde dehydrogenase family
MTP13_RS05505	COG2084	Dehydrogenase
MTP13_RS05510	COG1454	alcohol dehydrogenase
MTP13_RS05530	COG0598	Magnesium transport protein CorA
MTP13_RS05540	COG0443	Heat shock 70 kDa protein
MTP13_RS05545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MTP13_RS05550	COG0484	heat shock protein binding
MTP13_RS05555	COG0789	Transcriptional regulator
MTP13_RS05565	COG2813	Specifically methylates the guanine in position
MTP13_RS05570	COG3739	integral membrane protein
MTP13_RS05575	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MTP13_RS05630	COG0628	permease
MTP13_RS05650	COG3424	synthase
MTP13_RS05660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MTP13_RS05670	COG2814	Major facilitator Superfamily
MTP13_RS05680	COG0542	response to heat
MTP13_RS05685	COG2211	Major facilitator Superfamily
MTP13_RS05705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS05720	COG2353	YceI-like domain
MTP13_RS05755	COG2272	Belongs to the type-B carboxylesterase lipase family
MTP13_RS05790	COG5297	Belongs to the glycosyl hydrolase family 6
MTP13_RS05790	COG3250	beta-galactosidase activity
MTP13_RS05830	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MTP13_RS05840	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MTP13_RS05845	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MTP13_RS05880	COG1360	Flagellar Motor Protein
MTP13_RS05915	COG1176	ABC-type spermidine putrescine transport system, permease component I
MTP13_RS05925	COG3842	ATPase activity
MTP13_RS05930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MTP13_RS05935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTP13_RS05955	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MTP13_RS05975	COG1157	protein secretion by the type III secretion system
MTP13_RS05985	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MTP13_RS05990	COG1766	The M ring may be actively involved in energy transduction
MTP13_RS05995	COG1677	Flagellar hook-basal body complex protein FliE
MTP13_RS06005	COG1815	bacterial-type flagellum-dependent cell motility
MTP13_RS06025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MTP13_RS06100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MTP13_RS06115	COG0477	Major facilitator Superfamily
MTP13_RS06120	COG1228	amidohydrolase
MTP13_RS06135	COG4152	abc transporter atp-binding protein
MTP13_RS06140	COG2197	response regulator
MTP13_RS06145	COG4585	Histidine kinase
MTP13_RS06165	COG0640	Transcriptional regulator
MTP13_RS06210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTP13_RS06220	COG1116	anion transmembrane transporter activity
MTP13_RS06230	COG0778	Nitroreductase
MTP13_RS06230	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MTP13_RS06240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS06245	COG1920	GTP binding
MTP13_RS06250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS06260	COG1120	ATPase activity
MTP13_RS06265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP13_RS06280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MTP13_RS06285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS06295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTP13_RS06300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTP13_RS06305	COG0251	oxidation-reduction process
MTP13_RS06345	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MTP13_RS06355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MTP13_RS06365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MTP13_RS06410	COG3340	Belongs to the peptidase S51 family
MTP13_RS06415	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MTP13_RS06425	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MTP13_RS06450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MTP13_RS06465	COG0598	Magnesium transport protein CorA
MTP13_RS06485	COG0137	argininosuccinate synthase activity
MTP13_RS06495	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MTP13_RS06515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MTP13_RS06525	COG3279	Response regulator of the LytR AlgR family
MTP13_RS06530	COG3275	phosphorelay sensor kinase activity
MTP13_RS06540	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MTP13_RS06550	COG1725	Transcriptional regulator
MTP13_RS06555	COG0842	Transport permease protein
MTP13_RS06555	COG1129	ABC transporter
MTP13_RS06565	COG1136	(ABC) transporter
MTP13_RS06575	COG1605	Chorismate mutase
MTP13_RS06575	COG0287	Prephenate dehydrogenase
MTP13_RS06615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MTP13_RS06620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MTP13_RS06625	COG2814	Major facilitator Superfamily
MTP13_RS06635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MTP13_RS06650	COG1063	alcohol dehydrogenase
MTP13_RS06655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MTP13_RS06660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTP13_RS06665	COG3639	organic phosphonate transmembrane transporter activity
MTP13_RS06670	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MTP13_RS06675	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MTP13_RS06715	COG0047	phosphoribosylformylglycinamidine synthase activity
MTP13_RS06720	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MTP13_RS06745	COG3483	tryptophan 2,3-dioxygenase activity
MTP13_RS06755	COG2514	catechol 2,3-dioxygenase activity
MTP13_RS06760	COG3226	Transcriptional regulator
MTP13_RS06770	COG0747	negative chemotaxis
MTP13_RS06785	COG0673	inositol 2-dehydrogenase activity
MTP13_RS06790	COG1929	Belongs to the glycerate kinase type-1 family
MTP13_RS06805	COG1175	transmembrane transport
MTP13_RS06815	COG2188	Transcriptional regulator
MTP13_RS06835	COG2188	Transcriptional regulator
MTP13_RS06840	COG0673	inositol 2-dehydrogenase activity
MTP13_RS06850	COG1175	transmembrane transport
MTP13_RS06865	COG1609	Transcriptional regulator
MTP13_RS06875	COG1129	ABC transporter
MTP13_RS06880	COG1172	Belongs to the binding-protein-dependent transport system permease family
MTP13_RS06925	COG5002	protein histidine kinase activity
MTP13_RS06930	COG0745	RESPONSE REGULATOR receiver
MTP13_RS06935	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MTP13_RS06940	COG0151	Belongs to the GarS family
MTP13_RS06950	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MTP13_RS06955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP13_RS06960	COG4558	Periplasmic binding protein
MTP13_RS07135	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MTP13_RS07145	COG0702	epimerase
MTP13_RS07150	COG0415	Belongs to the DNA photolyase family
MTP13_RS07180	COG2267	carboxylic ester hydrolase activity
MTP13_RS07210	COG4166	transmembrane transport
MTP13_RS07215	COG0601	transmembrane transport
MTP13_RS07225	COG4172	Belongs to the ABC transporter superfamily
MTP13_RS07235	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MTP13_RS07260	COG0531	amino acid
MTP13_RS07325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MTP13_RS07350	COG2217	Heavy metal translocating P-type atpase
MTP13_RS07375	COG1228	amidohydrolase
MTP13_RS07380	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MTP13_RS07390	COG0765	amino acid transport
MTP13_RS07410	COG0739	heme binding
MTP13_RS07410	COG0741	lytic transglycosylase activity
MTP13_RS07410	COG1196	nuclear chromosome segregation
MTP13_RS07425	COG0586	Pfam SNARE associated Golgi protein
MTP13_RS07440	COG2197	response regulator
MTP13_RS07470	COG3655	Transcriptional regulator
MTP13_RS07480	COG0010	Belongs to the arginase family
MTP13_RS07495	COG2205	protein histidine kinase activity
MTP13_RS07500	COG0745	RESPONSE REGULATOR receiver
MTP13_RS07535	COG2186	Transcriptional regulator
MTP13_RS07555	COG2066	Belongs to the glutaminase family
MTP13_RS07565	COG1609	Transcriptional regulator
MTP13_RS07585	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MTP13_RS07590	COG0402	S-adenosylhomocysteine deaminase activity
MTP13_RS07595	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MTP13_RS07600	COG0747	negative chemotaxis
MTP13_RS07610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP13_RS07625	COG4166	transmembrane transport
MTP13_RS07630	COG0657	acetylesterase activity
MTP13_RS07645	COG0514	ATP-dependent DNA helicase (RecQ)
MTP13_RS07650	COG0477	Major facilitator Superfamily
MTP13_RS07660	COG1024	Enoyl-CoA hydratase
MTP13_RS07665	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTP13_RS07670	COG1012	belongs to the aldehyde dehydrogenase family
MTP13_RS07670	COG2030	dehydratase
MTP13_RS07705	COG1309	transcriptional regulator
MTP13_RS07715	COG2050	protein possibly involved in aromatic compounds catabolism
MTP13_RS07720	COG3396	Phenylacetate-CoA oxygenase
MTP13_RS07725	COG3460	Phenylacetate-CoA oxygenase
MTP13_RS07730	COG3396	Phenylacetate-CoA oxygenase
MTP13_RS07735	COG2151	metal-sulfur cluster biosynthetic enzyme
MTP13_RS07740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MTP13_RS07760	COG1609	Transcriptional regulator
MTP13_RS07770	COG1175	transmembrane transport
MTP13_RS07775	COG0395	ABC-type sugar transport system, permease component
MTP13_RS07780	COG1320	monovalent cation:proton antiporter activity
MTP13_RS07795	COG0651	ATP synthesis coupled electron transport
MTP13_RS07800	COG1006	Multisubunit Na H antiporter MnhC subunit
MTP13_RS07805	COG2111	Na H antiporter
MTP13_RS07805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MTP13_RS07845	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MTP13_RS07850	COG3845	ABC transporter
MTP13_RS07860	COG0577	efflux transmembrane transporter activity
MTP13_RS07865	COG1136	(ABC) transporter
MTP13_RS07865	COG0577	efflux transmembrane transporter activity
MTP13_RS07880	COG0745	RESPONSE REGULATOR receiver
MTP13_RS07885	COG2205	protein histidine kinase activity
MTP13_RS07890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS07905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS07935	COG2957	Belongs to the agmatine deiminase family
MTP13_RS07960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MTP13_RS07980	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MTP13_RS07985	COG4129	membrane
MTP13_RS07995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MTP13_RS08000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MTP13_RS08010	COG4977	sequence-specific DNA binding
MTP13_RS08025	COG0352	thiamine-phosphate diphosphorylase activity
MTP13_RS08025	COG0351	phosphomethylpyrimidine kinase
MTP13_RS08025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MTP13_RS08030	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MTP13_RS08035	COG1690	Belongs to the RtcB family
MTP13_RS08040	COG3620	sequence-specific DNA binding
MTP13_RS08045	COG0747	negative chemotaxis
MTP13_RS08050	COG0601	transmembrane transport
MTP13_RS08055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP13_RS08060	COG0444	Belongs to the ABC transporter superfamily
MTP13_RS08065	COG4608	Belongs to the ABC transporter superfamily
MTP13_RS08085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MTP13_RS08090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTP13_RS08150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MTP13_RS08155	COG1737	Transcriptional regulator
MTP13_RS08165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MTP13_RS08170	COG1653	transport
MTP13_RS08175	COG1175	transmembrane transport
MTP13_RS08190	COG1846	Transcriptional regulator
MTP13_RS08195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTP13_RS08200	COG0765	amino acid transport
MTP13_RS08205	COG1126	abc transporter atp-binding protein
MTP13_RS08215	COG0702	epimerase
MTP13_RS08220	COG1733	regulation of RNA biosynthetic process
MTP13_RS08250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTP13_RS08265	COG1846	Transcriptional regulator
MTP13_RS08270	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTP13_RS08285	COG0646	methionine synthase
MTP13_RS08285	COG1410	methionine synthase
MTP13_RS08295	COG3845	ABC transporter
MTP13_RS08315	COG1278	Cold shock
MTP13_RS08330	COG0640	Transcriptional regulator
MTP13_RS08345	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MTP13_RS08400	COG4172	Belongs to the ABC transporter superfamily
MTP13_RS08405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP13_RS08425	COG0737	Belongs to the 5'-nucleotidase family
MTP13_RS08425	COG4085	toxin activity
MTP13_RS08425	COG1525	nuclease
MTP13_RS08430	COG4172	Belongs to the ABC transporter superfamily
MTP13_RS08435	COG0444	Belongs to the ABC transporter superfamily
MTP13_RS08440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP13_RS08445	COG0601	transmembrane transport
MTP13_RS08450	COG4166	transmembrane transport
MTP13_RS08495	COG0039	L-malate dehydrogenase activity
MTP13_RS08535	COG0531	amino acid
MTP13_RS08610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MTP13_RS08615	COG0037	tRNA processing
MTP13_RS08625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MTP13_RS08630	COG0302	gtp cyclohydrolase
MTP13_RS08635	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MTP13_RS08640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MTP13_RS08670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MTP13_RS08675	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MTP13_RS08690	COG4172	Belongs to the ABC transporter superfamily
MTP13_RS08695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP13_RS08700	COG0601	transmembrane transport
MTP13_RS08740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MTP13_RS08775	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MTP13_RS08815	COG3845	ABC transporter
MTP13_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS08825	COG1309	transcriptional regulator
MTP13_RS08845	COG0300	oxidoreductase activity
MTP13_RS08860	COG1546	Belongs to the CinA family
MTP13_RS08860	COG1058	Belongs to the CinA family
MTP13_RS08865	COG1278	Cold shock
MTP13_RS08890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTP13_RS08910	COG0477	Major facilitator Superfamily
MTP13_RS08925	COG2186	Transcriptional regulator
MTP13_RS08935	COG1175	transmembrane transport
MTP13_RS08955	COG3718	enzyme involved in inositol metabolism
MTP13_RS08960	COG3962	Belongs to the TPP enzyme family
MTP13_RS08965	COG0363	glucosamine-6-phosphate deaminase activity
MTP13_RS08980	COG1178	ABC-type Fe3 transport system permease component
MTP13_RS09000	COG0673	inositol 2-dehydrogenase activity
MTP13_RS09005	COG2188	Transcriptional regulator
MTP13_RS09010	COG0531	amino acid
MTP13_RS09075	COG1253	flavin adenine dinucleotide binding
MTP13_RS09090	COG0513	Belongs to the DEAD box helicase family
MTP13_RS09125	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MTP13_RS09155	COG0085	RNA polymerase activity
MTP13_RS09160	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MTP13_RS09265	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MTP13_RS09270	COG0049	tRNA binding
MTP13_RS09275	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MTP13_RS09280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MTP13_RS09285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MTP13_RS09285	COG2755	lipolytic protein G-D-S-L family
MTP13_RS09295	COG0051	transcription antitermination factor activity, RNA binding
MTP13_RS09300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MTP13_RS09305	COG0088	Forms part of the polypeptide exit tunnel
MTP13_RS09310	COG0089	rRNA binding
MTP13_RS09315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MTP13_RS09320	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MTP13_RS09325	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MTP13_RS09330	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MTP13_RS09335	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MTP13_RS09345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MTP13_RS09350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MTP13_RS09355	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MTP13_RS09360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MTP13_RS09365	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MTP13_RS09370	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MTP13_RS09375	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MTP13_RS09380	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MTP13_RS09385	COG1841	ribosomal large subunit assembly
MTP13_RS09390	COG0200	Binds to the 23S rRNA
MTP13_RS09400	COG0563	adenylate kinase activity
MTP13_RS09410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MTP13_RS09415	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MTP13_RS09425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MTP13_RS09430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MTP13_RS09435	COG0202	RNA polymerase activity
MTP13_RS09440	COG0203	ribosomal protein L17
MTP13_RS09445	COG0101	tRNA pseudouridine synthase activity
MTP13_RS09450	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MTP13_RS09455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MTP13_RS09460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MTP13_RS09465	COG1072	(Pantothenic acid kinase))
MTP13_RS09470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MTP13_RS09475	COG0736	holo-[acyl-carrier-protein] synthase activity
MTP13_RS09480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MTP13_RS09485	COG0802	atpase or kinase
MTP13_RS09490	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MTP13_RS09500	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MTP13_RS09525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MTP13_RS09565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MTP13_RS09570	COG0488	(ABC) transporter
MTP13_RS09575	COG0516	GMP reductase activity
MTP13_RS09580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MTP13_RS09595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MTP13_RS09595	COG0519	Catalyzes the synthesis of GMP from XMP
MTP13_RS09600	COG0039	L-malate dehydrogenase activity
MTP13_RS09610	COG4941	Belongs to the sigma-70 factor family
MTP13_RS09620	COG0584	glycerophosphoryl diester phosphodiesterase
MTP13_RS09650	COG1131	(ABC) transporter
MTP13_RS09660	COG1476	TRANSCRIPTIONal
MTP13_RS09665	COG0045	succinate-CoA ligase (ADP-forming) activity
MTP13_RS09690	COG0138	bifunctional purine biosynthesis protein purh
MTP13_RS09700	COG1834	amidinotransferase
MTP13_RS09705	COG1136	(ABC) transporter
MTP13_RS09710	COG0577	efflux transmembrane transporter activity
MTP13_RS09710	COG1136	(ABC) transporter
MTP13_RS09730	COG1132	(ABC) transporter
MTP13_RS09740	COG2197	response regulator
MTP13_RS09765	COG0538	isocitrate dehydrogenase activity
MTP13_RS09770	COG2217	Heavy metal translocating P-type atpase
MTP13_RS09785	COG1175	transmembrane transport
MTP13_RS09790	COG0395	ABC-type sugar transport system, permease component
MTP13_RS09795	COG1472	Belongs to the glycosyl hydrolase 3 family
MTP13_RS09805	COG0363	glucosamine-6-phosphate deaminase activity
MTP13_RS09835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MTP13_RS09840	COG1349	DNA-binding transcription factor activity
MTP13_RS09845	COG0191	fructose-bisphosphate aldolase activity
MTP13_RS09860	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MTP13_RS09875	COG0395	ABC-type sugar transport system, permease component
MTP13_RS09885	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MTP13_RS09890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MTP13_RS09910	COG2089	acid synthase
MTP13_RS09935	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MTP13_RS09950	COG2017	converts alpha-aldose to the beta-anomer
MTP13_RS09960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS09985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MTP13_RS10010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MTP13_RS10015	COG0745	RESPONSE REGULATOR receiver
MTP13_RS10025	COG3485	protocatechuate 3,4-dioxygenase
MTP13_RS10040	COG0588	phosphoglycerate mutase activity
MTP13_RS10050	COG5002	protein histidine kinase activity
MTP13_RS10055	COG0745	RESPONSE REGULATOR receiver
MTP13_RS10070	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MTP13_RS10070	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MTP13_RS10075	COG0215	cysteine-tRNA ligase activity
MTP13_RS10085	COG3871	stress protein (general stress protein 26)
MTP13_RS10095	COG3842	ATPase activity
MTP13_RS10130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MTP13_RS10145	COG1278	Cold shock
MTP13_RS10150	COG0459	protein refolding
MTP13_RS10160	COG2205	protein histidine kinase activity
MTP13_RS10165	COG0745	RESPONSE REGULATOR receiver
MTP13_RS10170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MTP13_RS10180	COG1061	Type III restriction enzyme res subunit
MTP13_RS10195	COG1278	Cold shock
MTP13_RS10210	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MTP13_RS10220	COG0791	NLP P60 protein
MTP13_RS10230	COG1388	LysM domain
MTP13_RS10230	COG3942	CHAP domain
MTP13_RS10250	COG4941	Belongs to the sigma-70 factor family
MTP13_RS10260	COG1793	dna ligase
MTP13_RS10270	COG0686	Belongs to the AlaDH PNT family
MTP13_RS10285	COG1970	mechanosensitive ion channel activity
MTP13_RS10300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MTP13_RS10335	COG3069	C4-dicarboxylate transmembrane transporter activity
MTP13_RS10340	COG1957	nucleoside hydrolase
MTP13_RS10350	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MTP13_RS10370	COG0442	prolyl-tRNA aminoacylation
MTP13_RS10390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MTP13_RS10440	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MTP13_RS10475	COG0395	ABC-type sugar transport system, permease component
MTP13_RS10500	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MTP13_RS10510	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS10515	COG5002	protein histidine kinase activity
MTP13_RS10535	COG0745	RESPONSE REGULATOR receiver
MTP13_RS10550	COG0601	transmembrane transport
MTP13_RS10555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP13_RS10560	COG0444	Belongs to the ABC transporter superfamily
MTP13_RS10565	COG4608	Belongs to the ABC transporter superfamily
MTP13_RS10570	COG1846	Transcriptional regulator
MTP13_RS10570	COG1940	carbohydrate kinase activity
MTP13_RS10575	COG1486	melibiose metabolic process
MTP13_RS10585	COG0579	oxidoreductase
MTP13_RS10590	COG0488	(ABC) transporter
MTP13_RS10625	COG1408	metallophosphoesterase
MTP13_RS10630	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MTP13_RS10645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MTP13_RS10680	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MTP13_RS10735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MTP13_RS10735	COG1754	DNA topoisomerase type I activity
MTP13_RS10740	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MTP13_RS10745	COG0470	DNA polymerase III
MTP13_RS10760	COG0477	Major facilitator Superfamily
MTP13_RS10765	COG1228	amidohydrolase
MTP13_RS10790	COG1335	isochorismatase
MTP13_RS10795	COG0596	Alpha beta hydrolase
MTP13_RS10805	COG1012	belongs to the aldehyde dehydrogenase family
MTP13_RS10815	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MTP13_RS10825	COG3971	2-oxopent-4-enoate hydratase activity
MTP13_RS10840	COG0747	negative chemotaxis
MTP13_RS10850	COG0444	Belongs to the ABC transporter superfamily
MTP13_RS10870	COG2814	Major facilitator Superfamily
MTP13_RS10890	COG1063	alcohol dehydrogenase
MTP13_RS10895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MTP13_RS10900	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS10920	COG3226	Transcriptional regulator
MTP13_RS10935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTP13_RS10945	COG1116	anion transmembrane transporter activity
MTP13_RS10975	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS11030	COG0183	Belongs to the thiolase family
MTP13_RS11050	COG3214	Protein conserved in bacteria
MTP13_RS11060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MTP13_RS11065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MTP13_RS11085	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MTP13_RS11095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MTP13_RS11115	COG0114	fumarate hydratase activity
MTP13_RS11120	COG0288	reversible hydration of carbon dioxide
MTP13_RS11130	COG1722	exodeoxyribonuclease VII activity
MTP13_RS11135	COG1570	exodeoxyribonuclease VII activity
MTP13_RS11140	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MTP13_RS11165	COG0191	fructose-bisphosphate aldolase activity
MTP13_RS11170	COG1494	fructose-1,6-bisphosphatase
MTP13_RS11185	COG1322	Protein conserved in bacteria
MTP13_RS11200	COG0012	GTP binding
MTP13_RS11225	COG1309	transcriptional regulator
MTP13_RS11245	COG0477	Major facilitator Superfamily
MTP13_RS11270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MTP13_RS11285	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MTP13_RS11290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTP13_RS11300	COG2890	protein-(glutamine-N5) methyltransferase activity
MTP13_RS11315	COG2814	Major facilitator Superfamily
MTP13_RS11325	COG1104	cysteine desulfurase activity
MTP13_RS11335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MTP13_RS11340	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MTP13_RS11350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MTP13_RS11355	COG0509	glycine decarboxylation via glycine cleavage system
MTP13_RS11360	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MTP13_RS11360	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MTP13_RS11375	COG0747	negative chemotaxis
MTP13_RS11380	COG0601	transmembrane transport
MTP13_RS11395	COG1217	gtp-binding protein TYPA
MTP13_RS11405	COG1024	Enoyl-CoA hydratase
MTP13_RS11440	COG2171	N-acyltransferase activity
MTP13_RS11445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTP13_RS11465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MTP13_RS11495	COG2239	Acts as a magnesium transporter
MTP13_RS11505	COG0006	proline dipeptidase activity
MTP13_RS11515	COG0613	PHP domain protein
MTP13_RS11520	COG0513	Belongs to the DEAD box helicase family
MTP13_RS11545	COG0210	DNA helicase
MTP13_RS11555	COG2816	NAD+ diphosphatase activity
MTP13_RS11570	COG3480	Lon protease (S16) C-terminal proteolytic domain
MTP13_RS11575	COG1615	UPF0182 protein
MTP13_RS11595	COG1396	sequence-specific DNA binding
MTP13_RS11600	COG0740	serine-type endopeptidase activity
MTP13_RS11605	COG0740	serine-type endopeptidase activity
MTP13_RS11620	COG1595	DNA-templated transcription, initiation
MTP13_RS11625	COG1053	succinate dehydrogenase
MTP13_RS11640	COG0531	amino acid
MTP13_RS11650	COG1309	transcriptional regulator
MTP13_RS11655	COG3973	AAA domain
MTP13_RS11665	COG1802	Transcriptional regulator
MTP13_RS11670	COG2188	Transcriptional regulator
MTP13_RS11680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MTP13_RS11690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MTP13_RS11805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MTP13_RS11810	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MTP13_RS11815	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MTP13_RS11835	COG0586	Pfam SNARE associated Golgi protein
MTP13_RS11845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS11930	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MTP13_RS11940	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MTP13_RS11950	COG2884	Cell division ATP-binding protein ftsE
MTP13_RS11955	COG2177	Part of the ABC transporter FtsEX involved in
MTP13_RS11960	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MTP13_RS11965	COG2365	Tyrosine phosphatase family
MTP13_RS11975	COG1120	ATPase activity
MTP13_RS11980	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP13_RS11985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP13_RS11990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTP13_RS12010	COG0667	Aldo Keto reductase
MTP13_RS12020	COG0483	inositol monophosphate 1-phosphatase activity
MTP13_RS12040	COG1122	ATPase activity
MTP13_RS12045	COG0183	Belongs to the thiolase family
MTP13_RS12055	COG1268	BioY protein
MTP13_RS12075	COG2409	Drug exporters of the RND superfamily
MTP13_RS12090	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MTP13_RS12095	COG0129	dihydroxy-acid dehydratase activity
MTP13_RS12105	COG0440	acetolactate synthase activity
MTP13_RS12110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MTP13_RS12125	COG1175	transmembrane transport
MTP13_RS12150	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS12155	COG0179	Fumarylacetoacetate (FAA) hydrolase
MTP13_RS12160	COG4948	Mandelate Racemase Muconate Lactonizing
MTP13_RS12210	COG0477	Major facilitator Superfamily
MTP13_RS12220	COG0473	3-isopropylmalate dehydrogenase activity
MTP13_RS12225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MTP13_RS12230	COG0456	acetyltransferase
MTP13_RS12235	COG0179	Fumarylacetoacetate (FAA) hydrolase
MTP13_RS12245	COG0583	DNA-binding transcription factor activity
MTP13_RS12250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MTP13_RS12280	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MTP13_RS12295	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MTP13_RS12305	COG5290	Psort location Cytoplasmic, score
MTP13_RS12330	COG0346	lactoylglutathione lyase activity
MTP13_RS12350	COG2267	carboxylic ester hydrolase activity
MTP13_RS12360	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MTP13_RS12365	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MTP13_RS12370	COG3639	organic phosphonate transmembrane transporter activity
MTP13_RS12390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTP13_RS12395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MTP13_RS12400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MTP13_RS12405	COG3622	Belongs to the hyi family
MTP13_RS12415	COG3395	kinase activity
MTP13_RS12420	COG0235	Class ii aldolase
MTP13_RS12430	COG1957	nucleoside hydrolase
MTP13_RS12435	COG0477	Major facilitator Superfamily
MTP13_RS12460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTP13_RS12495	COG0402	S-adenosylhomocysteine deaminase activity
MTP13_RS12505	COG2188	Transcriptional regulator
MTP13_RS12510	COG0402	S-adenosylhomocysteine deaminase activity
MTP13_RS12515	COG0747	negative chemotaxis
MTP13_RS12520	COG0601	transmembrane transport
MTP13_RS12525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP13_RS12530	COG0444	Belongs to the ABC transporter superfamily
MTP13_RS12535	COG4608	Belongs to the ABC transporter superfamily
MTP13_RS12540	COG0402	S-adenosylhomocysteine deaminase activity
MTP13_RS12545	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MTP13_RS12570	COG0631	protein serine/threonine phosphatase activity
MTP13_RS12595	COG0714	Associated with various cellular activities
MTP13_RS12615	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MTP13_RS12620	COG0066	3-isopropylmalate dehydratase activity
MTP13_RS12625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MTP13_RS12630	COG0204	Acyl-transferase
MTP13_RS12630	COG0318	PFAM AMP-dependent synthetase and ligase
MTP13_RS12635	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MTP13_RS12640	COG1181	Belongs to the D-alanine--D-alanine ligase family
MTP13_RS12655	COG0742	ribosomal rna small subunit methyltransferase
MTP13_RS12665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MTP13_RS12670	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MTP13_RS12675	COG0714	Associated with various cellular activities
MTP13_RS12695	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MTP13_RS12700	COG0571	ribonuclease III activity
MTP13_RS12705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MTP13_RS12710	COG4948	Mandelate Racemase Muconate Lactonizing
MTP13_RS12715	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS12730	COG0395	ABC-type sugar transport system, permease component
MTP13_RS12745	COG1904	glucuronate isomerase
MTP13_RS12750	COG1609	Transcriptional regulator
MTP13_RS12760	COG1196	nuclear chromosome segregation
MTP13_RS12785	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MTP13_RS12790	COG0228	four-way junction DNA binding
MTP13_RS12795	COG1837	Belongs to the UPF0109 family
MTP13_RS12800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MTP13_RS12805	COG0336	Belongs to the RNA methyltransferase TrmD family
MTP13_RS12820	COG0335	large ribosomal subunit rRNA binding
MTP13_RS12825	COG0681	Belongs to the peptidase S26 family
MTP13_RS12830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MTP13_RS12840	COG0792	nuclease activity
MTP13_RS12860	COG4974	Belongs to the 'phage' integrase family
MTP13_RS12870	COG0052	Belongs to the universal ribosomal protein uS2 family
MTP13_RS12875	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MTP13_RS12880	COG0528	UMP kinase activity
MTP13_RS12885	COG0233	cytoplasmic translational termination
MTP13_RS12935	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MTP13_RS12940	COG0366	Alpha amylase catalytic
MTP13_RS12945	COG0058	SHG alpha-glucan phosphorylase activity
MTP13_RS12965	COG0482	sulfurtransferase activity
MTP13_RS12975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MTP13_RS12980	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MTP13_RS12985	COG0154	amidase activity
MTP13_RS12990	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MTP13_RS13000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MTP13_RS13010	COG4721	ABC-type cobalt transport system, permease component
MTP13_RS13015	COG4172	Belongs to the ABC transporter superfamily
MTP13_RS13025	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MTP13_RS13025	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MTP13_RS13050	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MTP13_RS13060	COG0475	glutathione-regulated potassium exporter activity
MTP13_RS13065	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MTP13_RS13080	COG0629	single-stranded DNA binding
MTP13_RS13110	COG1946	Acyl-CoA thioesterase
MTP13_RS13140	COG2197	response regulator
MTP13_RS13145	COG4585	Histidine kinase
MTP13_RS13170	COG0698	ribose 5-phosphate isomerase
MTP13_RS13180	COG2132	Multicopper oxidase
MTP13_RS13185	COG4585	Histidine kinase
MTP13_RS13190	COG2197	response regulator
MTP13_RS13195	COG0783	Belongs to the Dps family
MTP13_RS13210	COG0544	peptidyl-prolyl cis-trans isomerase activity
MTP13_RS13220	COG0740	serine-type endopeptidase activity
MTP13_RS13225	COG0740	serine-type endopeptidase activity
MTP13_RS13230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MTP13_RS13235	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MTP13_RS13255	COG0756	dUTP diphosphatase activity
MTP13_RS13270	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MTP13_RS13275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MTP13_RS13280	COG1024	Enoyl-CoA hydratase
MTP13_RS13280	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTP13_RS13285	COG0183	Belongs to the thiolase family
MTP13_RS13290	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MTP13_RS13350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MTP13_RS13360	COG2197	response regulator
MTP13_RS13365	COG4585	Histidine kinase
MTP13_RS13375	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MTP13_RS13385	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MTP13_RS13390	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MTP13_RS13400	COG0217	transcriptional regulatory protein
MTP13_RS13405	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MTP13_RS13410	COG0632	four-way junction helicase activity
MTP13_RS13415	COG2255	four-way junction helicase activity
MTP13_RS13425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MTP13_RS13430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MTP13_RS13435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MTP13_RS13445	COG1196	nuclear chromosome segregation
MTP13_RS13460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MTP13_RS13470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MTP13_RS13475	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MTP13_RS13485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MTP13_RS13490	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MTP13_RS13495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MTP13_RS13500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MTP13_RS13505	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MTP13_RS13510	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MTP13_RS13515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MTP13_RS13525	COG0477	Major facilitator Superfamily
MTP13_RS13530	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MTP13_RS13535	COG0540	Belongs to the ATCase OTCase family
MTP13_RS13540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MTP13_RS13550	COG0505	Belongs to the CarA family
MTP13_RS13555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MTP13_RS13560	COG0284	orotidine-5'-phosphate decarboxylase activity
MTP13_RS13565	COG0194	GDP metabolic process
MTP13_RS13570	COG1758	RNA polymerase activity
MTP13_RS13580	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MTP13_RS13590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MTP13_RS13600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MTP13_RS13605	COG0140	phosphoribosyl-ATP diphosphatase activity
MTP13_RS13610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MTP13_RS13615	COG0107	imidazoleglycerol-phosphate synthase activity
MTP13_RS13620	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MTP13_RS13640	COG0134	indole-3-glycerol-phosphate synthase activity
MTP13_RS13645	COG0133	tryptophan synthase activity
MTP13_RS13650	COG0159	tryptophan synthase activity
MTP13_RS13655	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MTP13_RS13660	COG0070	glutamate synthase
MTP13_RS13660	COG0067	glutamate synthase
MTP13_RS13660	COG0069	glutamate synthase activity
MTP13_RS13700	COG1090	epimerase
MTP13_RS13705	COG0539	negative regulation of cytoplasmic translation
MTP13_RS13715	COG0237	dephospho-CoA kinase activity
MTP13_RS13720	COG0556	nucleotide-excision repair
MTP13_RS13730	COG0322	excinuclease ABC activity
MTP13_RS13735	COG1660	Displays ATPase and GTPase activities
MTP13_RS13740	COG1481	regulation of sporulation
MTP13_RS13745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MTP13_RS13755	COG0126	phosphoglycerate kinase activity
MTP13_RS13760	COG0149	triose-phosphate isomerase activity
MTP13_RS13765	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MTP13_RS13775	COG0363	glucosamine-6-phosphate deaminase activity
MTP13_RS13790	COG0166	Belongs to the GPI family
MTP13_RS13795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MTP13_RS13805	COG0109	protoheme IX farnesyltransferase activity
MTP13_RS13830	COG0396	ATPase activity
MTP13_RS13835	COG2151	metal-sulfur cluster biosynthetic enzyme
MTP13_RS13840	COG2226	methyltransferase
MTP13_RS13855	COG0525	valine-tRNA ligase activity
MTP13_RS13860	COG4172	Belongs to the ABC transporter superfamily
MTP13_RS13865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP13_RS13885	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MTP13_RS13890	COG0285	dihydrofolate synthase activity
MTP13_RS13910	COG1530	ribonuclease E activity
MTP13_RS13920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MTP13_RS13925	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MTP13_RS13930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MTP13_RS13935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MTP13_RS13940	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MTP13_RS13950	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MTP13_RS13960	COG0799	negative regulation of ribosome biogenesis
MTP13_RS13995	COG0446	pyridine nucleotide-disulphide oxidoreductase
MTP13_RS14010	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTP13_RS14025	COG1522	sequence-specific DNA binding
MTP13_RS14040	COG1472	Belongs to the glycosyl hydrolase 3 family
MTP13_RS14055	COG0488	(ABC) transporter
MTP13_RS14090	COG0560	Phosphoserine phosphatase
MTP13_RS14095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MTP13_RS14100	COG0297	glycogen (starch) synthase activity
MTP13_RS14105	COG1119	ATPase activity
MTP13_RS14110	COG0254	rRNA binding
MTP13_RS14120	COG2267	carboxylic ester hydrolase activity
MTP13_RS14125	COG0438	transferase activity, transferring glycosyl groups
MTP13_RS14160	COG0626	cystathionine gamma-synthase activity
MTP13_RS14175	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS14185	COG0587	DNA-directed DNA polymerase activity
MTP13_RS14205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTP13_RS14210	COG1968	undecaprenyl-diphosphatase activity
MTP13_RS14245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MTP13_RS14250	COG0805	protein transport
MTP13_RS14285	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS14370	COG4762	Protein conserved in bacteria
MTP13_RS14380	COG1028	Short-chain dehydrogenase reductase Sdr
MTP13_RS14390	COG1461	Dihydroxyacetone kinase
MTP13_RS14395	COG2376	Dihydroxyacetone kinase
MTP13_RS14400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MTP13_RS14405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MTP13_RS14410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MTP13_RS14415	COG1845	cytochrome c oxidase, subunit III
MTP13_RS14420	COG2010	Cytochrome c
MTP13_RS14425	COG0723	plastoquinol--plastocyanin reductase activity
MTP13_RS14430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MTP13_RS14435	COG2226	methyltransferase
MTP13_RS14445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MTP13_RS14450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MTP13_RS14460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTP13_RS14475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MTP13_RS14480	COG0187	DNA topoisomerase II activity
MTP13_RS14500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MTP13_RS14510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MTP13_RS14515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MTP13_RS14520	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTP13_RS14530	COG0321	lipoyl(octanoyl) transferase activity
MTP13_RS14535	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MTP13_RS14550	COG0174	glutamine synthetase
MTP13_RS14555	COG0662	Cupin 2, conserved barrel domain protein
MTP13_RS14560	COG3422	double-strand break repair
MTP13_RS14565	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MTP13_RS14570	COG0174	glutamine synthetase
MTP13_RS14575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MTP13_RS14605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MTP13_RS14620	COG1476	TRANSCRIPTIONal
MTP13_RS14650	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MTP13_RS14665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MTP13_RS14670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTP13_RS14675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MTP13_RS14730	COG0242	peptide deformylase activity
MTP13_RS14755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTP13_RS14760	COG1116	anion transmembrane transporter activity
MTP13_RS14790	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MTP13_RS14805	COG3842	ATPase activity
MTP13_RS14815	COG1176	ABC-type spermidine putrescine transport system, permease component I
MTP13_RS14820	COG1177	transmembrane transport
MTP13_RS14830	COG3265	gluconokinase activity
MTP13_RS14845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MTP13_RS14850	COG4608	Belongs to the ABC transporter superfamily
MTP13_RS14855	COG4172	Belongs to the ABC transporter superfamily
MTP13_RS14865	COG0601	transmembrane transport
MTP13_RS14875	COG0358	DNA primase activity
MTP13_RS14880	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MTP13_RS14890	COG0442	prolyl-tRNA aminoacylation
MTP13_RS14905	COG1695	Transcriptional regulator
MTP13_RS14910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MTP13_RS14925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MTP13_RS14930	COG1381	Involved in DNA repair and RecF pathway recombination
MTP13_RS14940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MTP13_RS14945	COG0577	efflux transmembrane transporter activity
MTP13_RS14950	COG0577	efflux transmembrane transporter activity
MTP13_RS14950	COG1136	(ABC) transporter
MTP13_RS14955	COG2197	response regulator
MTP13_RS14960	COG4585	Histidine kinase
MTP13_RS14965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MTP13_RS14975	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MTP13_RS14985	COG0537	adenosine 5'-monophosphoramidase activity
MTP13_RS14995	COG0484	heat shock protein binding
MTP13_RS15000	COG1420	regulation of RNA biosynthetic process
MTP13_RS15020	COG4762	Protein conserved in bacteria
MTP13_RS15025	COG0481	GTPase activity
MTP13_RS15030	COG4585	Histidine kinase
MTP13_RS15035	COG2197	response regulator
MTP13_RS15045	COG0268	Binds directly to 16S ribosomal RNA
MTP13_RS15060	COG0495	leucyl-tRNA aminoacylation
MTP13_RS15065	COG0512	Glutamine amidotransferase of anthranilate synthase
MTP13_RS15065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MTP13_RS15070	COG4988	ABC transporter
MTP13_RS15075	COG4988	ABC transporter
MTP13_RS15080	COG1294	oxidase, subunit
MTP13_RS15085	COG1271	oxidase subunit
MTP13_RS15115	COG1174	glycine betaine transport
MTP13_RS15135	COG0167	dihydroorotate dehydrogenase activity
MTP13_RS15140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MTP13_RS15145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MTP13_RS15150	COG0587	DNA-directed DNA polymerase activity
MTP13_RS15160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MTP13_RS15165	COG3599	regulation of cell shape
MTP13_RS15175	COG1799	cell septum assembly
MTP13_RS15185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MTP13_RS15195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MTP13_RS15200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MTP13_RS15210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MTP13_RS15215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MTP13_RS15225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MTP13_RS15240	COG0275	rRNA processing
MTP13_RS15245	COG2001	Belongs to the MraZ family
MTP13_RS15255	COG0142	geranyltranstransferase activity
MTP13_RS15265	COG1388	LysM domain
MTP13_RS15265	COG1705	Flagellar rod assembly protein muramidase FlgJ
MTP13_RS15270	COG0515	serine threonine protein kinase
MTP13_RS15270	COG2815	serine threonine protein kinase
MTP13_RS15275	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MTP13_RS15285	COG1940	carbohydrate kinase activity
MTP13_RS15300	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MTP13_RS15305	COG1192	Involved in chromosome partitioning
MTP13_RS15320	COG1716	ATPase activity
MTP13_RS15350	COG3012	SEC-C Motif Domain Protein
MTP13_RS15355	COG2357	RelA SpoT domain protein
MTP13_RS15375	COG0789	Transcriptional regulator
MTP13_RS15395	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MTP13_RS15400	COG1119	ATPase activity
MTP13_RS15410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MTP13_RS15435	COG1309	transcriptional regulator
MTP13_RS15440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MTP13_RS15445	COG0022	dehydrogenase e1 component
MTP13_RS15450	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTP13_RS15455	COG1733	regulation of RNA biosynthetic process
MTP13_RS15465	COG0693	protein deglycase activity
MTP13_RS15490	COG1733	regulation of RNA biosynthetic process
MTP13_RS15500	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MTP13_RS15515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MTP13_RS15560	COG1872	DUF167
MTP13_RS15565	COG1160	GTP binding
MTP13_RS15570	COG2197	response regulator
MTP13_RS15585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MTP13_RS15590	COG0287	Prephenate dehydrogenase
MTP13_RS15600	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MTP13_RS15625	COG0504	CTP synthase activity
MTP13_RS15630	COG0497	DNA recombination
MTP13_RS15635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MTP13_RS15650	COG1011	Hydrolase
MTP13_RS15680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MTP13_RS15695	COG2094	Belongs to the DNA glycosylase MPG family
MTP13_RS15700	COG0165	Argininosuccinate lyase
MTP13_RS15705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MTP13_RS15715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MTP13_RS15720	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MTP13_RS15725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MTP13_RS15730	COG0072	phenylalanine-tRNA ligase activity
MTP13_RS15730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTP13_RS15735	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MTP13_RS15740	COG0765	amino acid transport
MTP13_RS15745	COG0765	amino acid transport
MTP13_RS15750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTP13_RS15755	COG1126	abc transporter atp-binding protein
MTP13_RS15760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MTP13_RS15765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MTP13_RS15770	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MTP13_RS15775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MTP13_RS15790	COG1201	RNA secondary structure unwinding
MTP13_RS15800	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MTP13_RS15805	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MTP13_RS15810	COG0131	Imidazoleglycerol-phosphate dehydratase
MTP13_RS15815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MTP13_RS15825	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MTP13_RS15840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MTP13_RS15845	COG2813	Specifically methylates the guanine in position
MTP13_RS15850	COG2807	transmembrane transport
MTP13_RS15855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MTP13_RS15860	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MTP13_RS15865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MTP13_RS15875	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MTP13_RS15905	COG3290	protein histidine kinase activity
MTP13_RS15915	COG1058	Belongs to the CinA family
MTP13_RS15915	COG1546	Belongs to the CinA family
MTP13_RS15925	COG1674	ftsk spoiiie
MTP13_RS15930	COG0577	efflux transmembrane transporter activity
MTP13_RS15930	COG1136	(ABC) transporter
MTP13_RS15935	COG0577	efflux transmembrane transporter activity
MTP13_RS15935	COG1136	(ABC) transporter
MTP13_RS15945	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MTP13_RS15950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MTP13_RS15960	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MTP13_RS15965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MTP13_RS15990	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MTP13_RS16005	COG0612	Peptidase, M16
MTP13_RS16010	COG0667	Aldo Keto reductase
MTP13_RS16025	COG1960	acyl-CoA dehydrogenase activity
MTP13_RS16035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MTP13_RS16050	COG2154	pterin-4-alpha-carbinolamine dehydratase
MTP13_RS16055	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTP13_RS16060	COG0022	dehydrogenase e1 component
MTP13_RS16085	COG1185	polyribonucleotide nucleotidyltransferase activity
MTP13_RS16110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS16115	COG0463	Glycosyl transferase, family 2
MTP13_RS16125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MTP13_RS16135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP13_RS16150	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MTP13_RS16155	COG3189	MarR family transcriptional regulator
MTP13_RS16185	COG0545	Peptidyl-prolyl cis-trans isomerase
MTP13_RS16195	COG0277	FAD linked oxidase domain protein
MTP13_RS16205	COG0179	Fumarylacetoacetate (FAA) hydrolase
MTP13_RS16215	COG0833	amino acid
MTP13_RS16225	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MTP13_RS16240	COG2186	Transcriptional regulator
MTP13_RS16260	COG0277	FAD linked oxidase domain protein
MTP13_RS16275	COG2233	PERMEase
MTP13_RS16280	COG2252	PERMEase
MTP13_RS16295	COG0494	nUDIX hydrolase
MTP13_RS16305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTP13_RS16320	COG1937	Protein conserved in bacteria
MTP13_RS16330	COG1012	belongs to the aldehyde dehydrogenase family
MTP13_RS16335	COG1012	belongs to the aldehyde dehydrogenase family
MTP13_RS16340	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MTP13_RS16345	COG2390	Transcriptional regulator
MTP13_RS16355	COG0196	riboflavin kinase activity
MTP13_RS16370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MTP13_RS16375	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MTP13_RS16400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MTP13_RS16405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MTP13_RS16420	COG1611	Belongs to the LOG family
MTP13_RS16425	COG0442	prolyl-tRNA aminoacylation
MTP13_RS16440	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MTP13_RS16465	COG0183	Belongs to the thiolase family
MTP13_RS16480	COG2197	response regulator
MTP13_RS16485	COG4585	Histidine kinase
MTP13_RS16490	COG0750	zinc metalloprotease
MTP13_RS16495	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MTP13_RS16500	COG0318	PFAM AMP-dependent synthetase and ligase
MTP13_RS16500	COG0204	Acyl-transferase
MTP13_RS16515	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MTP13_RS16525	COG1177	transmembrane transport
MTP13_RS16535	COG3842	ATPase activity
MTP13_RS16545	COG1674	ftsk spoiiie
MTP13_RS16555	COG0631	protein serine/threonine phosphatase activity
MTP13_RS16565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MTP13_RS16575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MTP13_RS16580	COG2818	Glycosylase
MTP13_RS16595	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MTP13_RS16600	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MTP13_RS16605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MTP13_RS16610	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MTP13_RS16615	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MTP13_RS16620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MTP13_RS16625	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MTP13_RS16630	COG0356	it plays a direct role in the translocation of protons across the membrane
MTP13_RS16640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MTP13_RS16665	COG2890	protein-(glutamine-N5) methyltransferase activity
MTP13_RS16675	COG1045	serine acetyltransferase
MTP13_RS16685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MTP13_RS16695	COG0083	homoserine kinase activity
MTP13_RS16700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MTP13_RS16705	COG0460	homoserine dehydrogenase
MTP13_RS16710	COG0019	diaminopimelate decarboxylase activity
MTP13_RS16720	COG0018	arginyl-trna synthetase
MTP13_RS16740	COG1595	DNA-templated transcription, initiation
MTP13_RS16760	COG1842	Phage shock protein A
MTP13_RS16765	COG0010	Belongs to the arginase family
MTP13_RS16780	COG1120	ATPase activity
MTP13_RS16785	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP13_RS16790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP13_RS16800	COG0154	amidase activity
MTP13_RS16820	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
MTP13_RS16825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MTP13_RS16845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MTP13_RS16860	COG2197	response regulator
MTP13_RS16865	COG2814	Major facilitator Superfamily
MTP13_RS16890	COG0765	amino acid transport
MTP13_RS16905	COG1011	Hydrolase
MTP13_RS16930	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTP13_RS16930	COG0567	Dehydrogenase, E1 component
MTP13_RS16935	COG2409	Drug exporters of the RND superfamily
MTP13_RS16945	COG1595	DNA-templated transcription, initiation
MTP13_RS16950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MTP13_RS17005	COG0653	protein targeting
MTP13_RS17010	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MTP13_RS17020	COG5401	PFAM Sporulation and spore germination
MTP13_RS17025	COG5002	protein histidine kinase activity
MTP13_RS17025	COG5000	phosphorelay sensor kinase activity
MTP13_RS17030	COG0745	RESPONSE REGULATOR receiver
MTP13_RS17050	COG0714	Associated with various cellular activities
MTP13_RS17060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MTP13_RS17075	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MTP13_RS17080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MTP13_RS17110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MTP13_RS17125	COG1482	cell wall glycoprotein biosynthetic process
MTP13_RS17130	COG1960	acyl-CoA dehydrogenase activity
MTP13_RS17135	COG0463	Glycosyl transferase, family 2
MTP13_RS17140	COG1215	transferase activity, transferring glycosyl groups
MTP13_RS17145	COG1442	glycosyl transferase family 8
MTP13_RS17145	COG1216	Glycosyl transferase, family 2
MTP13_RS17155	COG2755	lipolytic protein G-D-S-L family
MTP13_RS17155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MTP13_RS17160	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MTP13_RS17215	COG1216	Glycosyl transferase, family 2
MTP13_RS17230	COG1132	(ABC) transporter
MTP13_RS17250	COG1216	Glycosyl transferase, family 2
MTP13_RS17295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MTP13_RS17300	COG0438	transferase activity, transferring glycosyl groups
MTP13_RS17330	COG1316	TRANSCRIPTIONal
MTP13_RS17375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MTP13_RS17400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MTP13_RS17405	COG0424	maF-like protein
MTP13_RS17410	COG4770	biotin carboxylase activity
MTP13_RS17420	COG0640	Transcriptional regulator
MTP13_RS17425	COG0789	Transcriptional regulator
MTP13_RS17450	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MTP13_RS17470	COG2233	PERMEase
MTP13_RS17490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MTP13_RS17505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MTP13_RS17520	COG1079	Belongs to the binding-protein-dependent transport system permease family
MTP13_RS17525	COG4603	Belongs to the binding-protein-dependent transport system permease family
MTP13_RS17530	COG3845	ABC transporter
MTP13_RS17540	COG1744	ABC transporter substrate-binding protein PnrA-like
MTP13_RS17550	COG2009	succinate dehydrogenase
MTP13_RS17565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MTP13_RS17590	COG0180	Tryptophanyl-tRNA synthetase
MTP13_RS17600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MTP13_RS17605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MTP13_RS17610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MTP13_RS17630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MTP13_RS17630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MTP13_RS17635	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MTP13_RS17645	COG0477	Major facilitator Superfamily
MTP13_RS17665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTP13_RS17670	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MTP13_RS17680	COG0529	Catalyzes the synthesis of activated sulfate
MTP13_RS17680	COG2895	sulfate adenylyltransferase (ATP) activity
MTP13_RS17695	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTP13_RS17705	COG1132	(ABC) transporter
MTP13_RS17715	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MTP13_RS17725	COG0501	Belongs to the peptidase M48B family
MTP13_RS17730	COG1704	LemA family
MTP13_RS17740	COG1131	(ABC) transporter
MTP13_RS17770	COG0248	Ppx GppA phosphatase
MTP13_RS17795	COG1404	Belongs to the peptidase S8 family
MTP13_RS17810	COG0148	phosphopyruvate hydratase activity
MTP13_RS17815	COG0124	histidyl-tRNA synthetase
MTP13_RS17825	COG1280	lysine exporter protein (LysE YggA)
MTP13_RS17830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MTP13_RS17845	COG0328	RNA-DNA hybrid ribonuclease activity
MTP13_RS17850	COG0193	aminoacyl-tRNA hydrolase activity
MTP13_RS17855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MTP13_RS17860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MTP13_RS17865	COG2149	membrane
MTP13_RS17885	COG0318	PFAM AMP-dependent synthetase and ligase
MTP13_RS17890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MTP13_RS17895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MTP13_RS17915	COG2378	regulation of single-species biofilm formation
MTP13_RS17925	COG2011	ABC-type metal ion transport system permease component
MTP13_RS17930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MTP13_RS17935	COG1464	Belongs to the NlpA lipoprotein family
MTP13_RS17950	COG0488	(ABC) transporter
MTP13_RS17955	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MTP13_RS17960	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MTP13_RS17965	COG0084	hydrolase, TatD family'
MTP13_RS17970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTP13_RS18000	COG0604	alcohol dehydrogenase
MTP13_RS18010	COG2076	Multidrug Resistance protein
MTP13_RS18020	COG2873	o-acetylhomoserine
MTP13_RS18025	COG1832	CoA-binding protein
MTP13_RS18045	COG1760	l-serine dehydratase
MTP13_RS18055	COG1362	aminopeptidase activity
MTP13_RS18060	COG0484	heat shock protein binding
MTP13_RS18085	COG1331	Highly conserved protein containing a thioredoxin domain
MTP13_RS18110	COG1643	Atp-dependent helicase
MTP13_RS18135	COG0656	L-ascorbic acid biosynthetic process
MTP13_RS18165	COG0475	glutathione-regulated potassium exporter activity