locus-tag	class	description
ELQ40_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ELQ40_RS00010	COG0592	DNA-directed DNA polymerase activity
ELQ40_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ELQ40_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ELQ40_RS00025	COG0187	DNA topoisomerase II activity
ELQ40_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ELQ40_RS00050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ELQ40_RS00085	COG0457	Tetratricopeptide repeat
ELQ40_RS00085	COG0705	Rhomboid family
ELQ40_RS00095	COG3764	Sortase (surface protein transpeptidase)
ELQ40_RS00105	COG0515	serine threonine protein kinase
ELQ40_RS00110	COG0515	serine threonine protein kinase
ELQ40_RS00115	COG0768	penicillin binding
ELQ40_RS00130	COG1716	ATPase activity
ELQ40_RS00135	COG1716	ATPase activity
ELQ40_RS00160	COG2261	transglycosylase associated protein
ELQ40_RS00175	COG0596	Alpha beta hydrolase
ELQ40_RS00185	COG0477	Major facilitator Superfamily
ELQ40_RS00190	COG3265	gluconokinase activity
ELQ40_RS00195	COG0659	secondary active sulfate transmembrane transporter activity
ELQ40_RS00205	COG3119	arylsulfatase activity
ELQ40_RS00210	COG2409	Drug exporters of the RND superfamily
ELQ40_RS00245	COG2188	Transcriptional regulator
ELQ40_RS00250	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ELQ40_RS00255	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ELQ40_RS00260	COG3639	organic phosphonate transmembrane transporter activity
ELQ40_RS00265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ELQ40_RS00275	COG1063	alcohol dehydrogenase
ELQ40_RS00285	COG0657	acetylesterase activity
ELQ40_RS00295	COG1053	succinate dehydrogenase
ELQ40_RS00305	COG3550	peptidyl-serine autophosphorylation
ELQ40_RS00325	COG2066	Belongs to the glutaminase family
ELQ40_RS00355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ELQ40_RS00370	COG3458	cephalosporin-C deacetylase activity
ELQ40_RS00385	COG1733	regulation of RNA biosynthetic process
ELQ40_RS00435	COG3591	Belongs to the peptidase S1B family
ELQ40_RS00435	COG1864	DNA RNA non-specific endonuclease
ELQ40_RS00470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ELQ40_RS00475	COG2207	Transcriptional regulator
ELQ40_RS00475	COG3708	Transcriptional regulator
ELQ40_RS00495	COG1846	Transcriptional regulator
ELQ40_RS00510	COG1082	Xylose isomerase domain protein TIM barrel
ELQ40_RS00515	COG0673	inositol 2-dehydrogenase activity
ELQ40_RS00525	COG1175	transmembrane transport
ELQ40_RS00530	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS00535	COG3842	ATPase activity
ELQ40_RS00545	COG0383	alpha-mannosidase activity
ELQ40_RS00550	COG2188	Transcriptional regulator
ELQ40_RS00580	COG3962	Belongs to the TPP enzyme family
ELQ40_RS00585	COG3718	enzyme involved in inositol metabolism
ELQ40_RS00600	COG4682	membrane
ELQ40_RS00625	COG1733	regulation of RNA biosynthetic process
ELQ40_RS00630	COG0477	Major facilitator Superfamily
ELQ40_RS00640	COG4716	Myosin-crossreactive antigen
ELQ40_RS00660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ELQ40_RS00675	COG2197	response regulator
ELQ40_RS00680	COG0386	Belongs to the glutathione peroxidase family
ELQ40_RS00685	COG2195	Cleaves the N-terminal amino acid of tripeptides
ELQ40_RS00710	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ELQ40_RS00720	COG0738	Major facilitator superfamily
ELQ40_RS00725	COG1063	alcohol dehydrogenase
ELQ40_RS00735	COG4221	oxidoreductase activity
ELQ40_RS00760	COG3590	peptidase
ELQ40_RS00790	COG0494	nUDIX hydrolase
ELQ40_RS00795	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ELQ40_RS00800	COG0423	glycine-tRNA ligase activity
ELQ40_RS00815	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ELQ40_RS00830	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ELQ40_RS00885	COG0142	geranyltranstransferase activity
ELQ40_RS00900	COG3253	May function as heme-dependent peroxidase
ELQ40_RS00905	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ELQ40_RS00910	COG0181	hydroxymethylbilane synthase activity
ELQ40_RS00925	COG1053	succinate dehydrogenase
ELQ40_RS00925	COG3976	FMN-binding domain protein
ELQ40_RS00935	COG1175	transmembrane transport
ELQ40_RS00940	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS00945	COG0113	porphobilinogen synthase activity
ELQ40_RS00950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ELQ40_RS00975	COG1131	(ABC) transporter
ELQ40_RS01010	COG1176	ABC-type spermidine putrescine transport system, permease component I
ELQ40_RS01015	COG1177	transmembrane transport
ELQ40_RS01020	COG3842	ATPase activity
ELQ40_RS01030	COG1819	glycosyl
ELQ40_RS01035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ELQ40_RS01040	COG1012	belongs to the aldehyde dehydrogenase family
ELQ40_RS01045	COG1054	Belongs to the UPF0176 family
ELQ40_RS01055	COG1280	lysine exporter protein (LysE YggA)
ELQ40_RS01065	COG1024	Enoyl-CoA hydratase
ELQ40_RS01075	COG2079	MmgE PrpD family protein
ELQ40_RS01080	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ELQ40_RS01105	COG1309	transcriptional regulator
ELQ40_RS01110	COG0477	Major facilitator Superfamily
ELQ40_RS01130	COG1733	regulation of RNA biosynthetic process
ELQ40_RS01165	COG1012	belongs to the aldehyde dehydrogenase family
ELQ40_RS01175	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ELQ40_RS01185	COG4067	protein conserved in archaea
ELQ40_RS01185	COG0189	ligase activity
ELQ40_RS01190	COG0569	domain protein
ELQ40_RS01190	COG0189	ligase activity
ELQ40_RS01215	COG3104	oligopeptide transport
ELQ40_RS01225	COG1216	Glycosyl transferase, family 2
ELQ40_RS01230	COG2814	Major facilitator Superfamily
ELQ40_RS01235	COG2207	Transcriptional regulator
ELQ40_RS01280	COG2186	Transcriptional regulator
ELQ40_RS01305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ELQ40_RS01325	COG1070	Carbohydrate kinase
ELQ40_RS01330	COG3347	Dehydrogenase
ELQ40_RS01330	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS01345	COG1879	ABC-type sugar transport system periplasmic component
ELQ40_RS01360	COG1129	ABC transporter
ELQ40_RS01370	COG3250	beta-galactosidase activity
ELQ40_RS01375	COG1609	Transcriptional regulator
ELQ40_RS01385	COG1175	transmembrane transport
ELQ40_RS01390	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS01400	COG1609	Transcriptional regulator
ELQ40_RS01425	COG1305	Transglutaminase-like
ELQ40_RS01435	COG2267	carboxylic ester hydrolase activity
ELQ40_RS01450	COG0095	Lipoate-protein ligase
ELQ40_RS01485	COG1175	transmembrane transport
ELQ40_RS01495	COG1876	peptidase activity
ELQ40_RS01500	COG2814	Major facilitator Superfamily
ELQ40_RS01515	COG2197	response regulator
ELQ40_RS01525	COG2733	membrane
ELQ40_RS01530	COG0077	Prephenate dehydratase
ELQ40_RS01545	COG1597	lipid kinase activity
ELQ40_RS01550	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ELQ40_RS01555	COG0561	phosphatase activity
ELQ40_RS01560	COG1316	TRANSCRIPTIONal
ELQ40_RS01570	COG1316	TRANSCRIPTIONal
ELQ40_RS01595	COG2826	transposase and inactivated derivatives, IS30 family
ELQ40_RS01600	COG2801	Transposase and inactivated derivatives
ELQ40_RS01620	COG0800	Aldolase
ELQ40_RS01630	COG1312	Catalyzes the dehydration of D-mannonate
ELQ40_RS01640	COG1904	glucuronate isomerase
ELQ40_RS01645	COG0246	Mannitol dehydrogenase
ELQ40_RS01650	COG1609	Transcriptional regulator
ELQ40_RS01655	COG1175	transmembrane transport
ELQ40_RS01660	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS01695	COG1653	transport
ELQ40_RS01700	COG1175	transmembrane transport
ELQ40_RS01705	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS01715	COG2755	lipolytic protein G-D-S-L family
ELQ40_RS01725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ELQ40_RS01745	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ELQ40_RS01770	COG0366	Alpha amylase catalytic
ELQ40_RS01780	COG4209	transmembrane transport
ELQ40_RS01785	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS01840	COG1414	Transcriptional regulator
ELQ40_RS01855	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ELQ40_RS01865	COG0505	Belongs to the CarA family
ELQ40_RS01880	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ELQ40_RS01905	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ELQ40_RS01910	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ELQ40_RS01915	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ELQ40_RS01935	COG3559	Exporter of polyketide antibiotics
ELQ40_RS01940	COG1131	(ABC) transporter
ELQ40_RS01945	COG0569	domain protein
ELQ40_RS01950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ELQ40_RS01995	COG0017	Asparaginyl-tRNA synthetase
ELQ40_RS02000	COG0406	alpha-ribazole phosphatase activity
ELQ40_RS02010	COG0785	Cytochrome C biogenesis protein
ELQ40_RS02015	COG1333	cytochrome c biogenesis protein
ELQ40_RS02020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ELQ40_RS02030	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
ELQ40_RS02030	COG1672	PFAM Archaeal ATPase
ELQ40_RS02040	COG4948	Mandelate Racemase Muconate Lactonizing
ELQ40_RS02070	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ELQ40_RS02075	COG2326	polyphosphate kinase activity
ELQ40_RS02085	COG2226	methyltransferase
ELQ40_RS02090	COG0142	geranyltranstransferase activity
ELQ40_RS02110	COG2197	response regulator
ELQ40_RS02125	COG0494	nUDIX hydrolase
ELQ40_RS02130	COG1666	GTP binding
ELQ40_RS02140	COG1609	Transcriptional regulator
ELQ40_RS02155	COG4251	negative regulation of phosphorylation
ELQ40_RS02185	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ELQ40_RS02190	COG0483	inositol monophosphate 1-phosphatase activity
ELQ40_RS02195	COG0739	heme binding
ELQ40_RS02205	COG0366	Alpha amylase catalytic
ELQ40_RS02210	COG2182	Extracellular solute-binding protein
ELQ40_RS02225	COG0366	Alpha amylase catalytic
ELQ40_RS02255	COG1222	aaa ATPase
ELQ40_RS02360	COG0640	Transcriptional regulator
ELQ40_RS02375	COG0456	acetyltransferase
ELQ40_RS02415	COG3285	dna ligase
ELQ40_RS02415	COG1793	dna ligase
ELQ40_RS02425	COG0431	NADPH-dependent FMN reductase
ELQ40_RS02430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ELQ40_RS02435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ELQ40_RS02440	COG0385	Bile acid
ELQ40_RS02495	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
ELQ40_RS02510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ELQ40_RS02515	COG4569	acetaldehyde dehydrogenase (acetylating) activity
ELQ40_RS02520	COG3971	2-oxopent-4-enoate hydratase activity
ELQ40_RS02540	COG3842	ATPase activity
ELQ40_RS02560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ELQ40_RS02600	COG2197	response regulator
ELQ40_RS02620	COG2030	dehydratase
ELQ40_RS02630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ELQ40_RS02640	COG2197	response regulator
ELQ40_RS02660	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ELQ40_RS02680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ELQ40_RS02690	COG0583	DNA-binding transcription factor activity
ELQ40_RS02700	COG3237	CsbD-like
ELQ40_RS02705	COG0436	Aminotransferase
ELQ40_RS02735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ELQ40_RS02740	COG0081	regulation of translation
ELQ40_RS02745	COG1254	Belongs to the acylphosphatase family
ELQ40_RS02750	COG1012	belongs to the aldehyde dehydrogenase family
ELQ40_RS02770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ELQ40_RS02775	COG0765	amino acid transport
ELQ40_RS02780	COG1126	abc transporter atp-binding protein
ELQ40_RS02785	COG0596	Alpha beta hydrolase
ELQ40_RS02805	COG1231	oxidoreductase activity
ELQ40_RS02820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ELQ40_RS02850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ELQ40_RS02860	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ELQ40_RS02905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ELQ40_RS02915	COG0415	Belongs to the DNA photolyase family
ELQ40_RS02935	COG0714	Associated with various cellular activities
ELQ40_RS02960	COG0631	protein serine/threonine phosphatase activity
ELQ40_RS02995	COG0673	inositol 2-dehydrogenase activity
ELQ40_RS03000	COG1129	ABC transporter
ELQ40_RS03005	COG1172	Belongs to the binding-protein-dependent transport system permease family
ELQ40_RS03010	COG1172	Belongs to the binding-protein-dependent transport system permease family
ELQ40_RS03050	COG2197	response regulator
ELQ40_RS03060	COG0577	efflux transmembrane transporter activity
ELQ40_RS03060	COG1136	(ABC) transporter
ELQ40_RS03070	COG0745	RESPONSE REGULATOR receiver
ELQ40_RS03075	COG2205	protein histidine kinase activity
ELQ40_RS03090	COG0477	Major facilitator Superfamily
ELQ40_RS03115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ELQ40_RS03120	COG0222	ribosome binding
ELQ40_RS03125	COG0673	inositol 2-dehydrogenase activity
ELQ40_RS03130	COG1609	Transcriptional regulator
ELQ40_RS03135	COG1653	transport
ELQ40_RS03140	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS03145	COG1175	transmembrane transport
ELQ40_RS03155	COG2814	Major facilitator Superfamily
ELQ40_RS03160	COG1609	Transcriptional regulator
ELQ40_RS03165	COG1653	transport
ELQ40_RS03170	COG1175	transmembrane transport
ELQ40_RS03175	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS03180	COG1132	(ABC) transporter
ELQ40_RS03195	COG0477	Major facilitator Superfamily
ELQ40_RS03215	COG0531	amino acid
ELQ40_RS03240	COG1609	Transcriptional regulator
ELQ40_RS03250	COG4213	ABC transporter substrate-binding protein
ELQ40_RS03255	COG1129	ABC transporter
ELQ40_RS03260	COG4214	carbohydrate transport
ELQ40_RS03275	COG2160	L-arabinose isomerase activity
ELQ40_RS03295	COG1879	ABC-type sugar transport system periplasmic component
ELQ40_RS03305	COG1172	Belongs to the binding-protein-dependent transport system permease family
ELQ40_RS03310	COG1172	Belongs to the binding-protein-dependent transport system permease family
ELQ40_RS03315	COG1609	Transcriptional regulator
ELQ40_RS03330	COG4585	Histidine kinase
ELQ40_RS03355	COG1780	Probably involved in ribonucleotide reductase function
ELQ40_RS03360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ELQ40_RS03365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ELQ40_RS03380	COG3959	Transketolase, thiamine diphosphate binding domain
ELQ40_RS03385	COG3958	Transketolase
ELQ40_RS03390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ELQ40_RS03400	COG1129	ABC transporter
ELQ40_RS03405	COG1172	Belongs to the binding-protein-dependent transport system permease family
ELQ40_RS03415	COG1082	Xylose isomerase domain protein TIM barrel
ELQ40_RS03425	COG2390	Transcriptional regulator
ELQ40_RS03435	COG0477	Major facilitator Superfamily
ELQ40_RS03470	COG1136	(ABC) transporter
ELQ40_RS03475	COG0577	efflux transmembrane transporter activity
ELQ40_RS03475	COG1136	(ABC) transporter
ELQ40_RS03490	COG1053	succinate dehydrogenase
ELQ40_RS03495	COG0583	DNA-binding transcription factor activity
ELQ40_RS03500	COG2814	Major facilitator Superfamily
ELQ40_RS03560	COG0745	RESPONSE REGULATOR receiver
ELQ40_RS03565	COG5002	protein histidine kinase activity
ELQ40_RS03575	COG2409	Drug exporters of the RND superfamily
ELQ40_RS03605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ELQ40_RS03615	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ELQ40_RS03635	COG1309	transcriptional regulator
ELQ40_RS03640	COG0318	PFAM AMP-dependent synthetase and ligase
ELQ40_RS03665	COG0559	Belongs to the binding-protein-dependent transport system permease family
ELQ40_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS03680	COG1960	acyl-CoA dehydrogenase activity
ELQ40_RS03690	COG0183	Belongs to the thiolase family
ELQ40_RS03695	COG1024	Enoyl-CoA hydratase
ELQ40_RS03695	COG1250	3-hydroxyacyl-CoA dehydrogenase
ELQ40_RS03720	COG3973	AAA domain
ELQ40_RS03770	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ELQ40_RS03775	COG1140	nitrate reductase beta subunit
ELQ40_RS03785	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ELQ40_RS03800	COG2267	carboxylic ester hydrolase activity
ELQ40_RS03820	COG0822	iron-sulfur transferase activity
ELQ40_RS03875	COG0640	Transcriptional regulator
ELQ40_RS03885	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS03895	COG3548	integral membrane protein
ELQ40_RS03910	COG0488	(ABC) transporter
ELQ40_RS03935	COG1595	DNA-templated transcription, initiation
ELQ40_RS03965	COG0640	Transcriptional regulator
ELQ40_RS04000	COG2814	Major facilitator Superfamily
ELQ40_RS04005	COG1846	Transcriptional regulator
ELQ40_RS04020	COG1253	flavin adenine dinucleotide binding
ELQ40_RS04040	COG0662	Cupin 2, conserved barrel domain protein
ELQ40_RS04055	COG1595	DNA-templated transcription, initiation
ELQ40_RS04065	COG0604	alcohol dehydrogenase
ELQ40_RS04065	COG3321	synthase
ELQ40_RS04065	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS04145	COG4941	Belongs to the sigma-70 factor family
ELQ40_RS04175	COG0596	Alpha beta hydrolase
ELQ40_RS04225	COG1280	lysine exporter protein (LysE YggA)
ELQ40_RS04240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ELQ40_RS04245	COG2133	pyrroloquinoline quinone binding
ELQ40_RS04260	COG1175	transmembrane transport
ELQ40_RS04265	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS04270	COG1609	Transcriptional regulator
ELQ40_RS04275	COG1621	beta-fructofuranosidase activity
ELQ40_RS04280	COG1621	beta-fructofuranosidase activity
ELQ40_RS04285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ELQ40_RS04310	COG0542	response to heat
ELQ40_RS04320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ELQ40_RS04345	COG1595	DNA-templated transcription, initiation
ELQ40_RS04395	COG2197	response regulator
ELQ40_RS04400	COG4585	Histidine kinase
ELQ40_RS04410	COG0454	-acetyltransferase
ELQ40_RS04430	COG1132	(ABC) transporter
ELQ40_RS04440	COG4977	sequence-specific DNA binding
ELQ40_RS04455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ELQ40_RS04460	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ELQ40_RS04465	COG1120	ATPase activity
ELQ40_RS04470	COG3250	beta-galactosidase activity
ELQ40_RS04475	COG1309	transcriptional regulator
ELQ40_RS04480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ELQ40_RS04490	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS04500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ELQ40_RS04520	COG0488	(ABC) transporter
ELQ40_RS04540	COG1396	sequence-specific DNA binding
ELQ40_RS04575	COG1609	Transcriptional regulator
ELQ40_RS04585	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS04590	COG1653	transport
ELQ40_RS04605	COG1595	DNA-templated transcription, initiation
ELQ40_RS04630	COG2755	lipolytic protein G-D-S-L family
ELQ40_RS04630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ELQ40_RS04640	COG1793	dna ligase
ELQ40_RS04675	COG0596	Alpha beta hydrolase
ELQ40_RS04680	COG0406	alpha-ribazole phosphatase activity
ELQ40_RS04705	COG2226	methyltransferase
ELQ40_RS04710	COG0626	cystathionine gamma-synthase activity
ELQ40_RS04745	COG1796	DNA polymerase
ELQ40_RS04745	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ELQ40_RS04755	COG1846	Transcriptional regulator
ELQ40_RS04780	COG0515	serine threonine protein kinase
ELQ40_RS04780	COG2815	serine threonine protein kinase
ELQ40_RS04795	COG4214	carbohydrate transport
ELQ40_RS04810	COG4552	Acetyltransferase involved in intracellular survival and related
ELQ40_RS04825	COG0673	inositol 2-dehydrogenase activity
ELQ40_RS04835	COG0673	inositol 2-dehydrogenase activity
ELQ40_RS04850	COG4948	Mandelate Racemase Muconate Lactonizing
ELQ40_RS04855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ELQ40_RS04870	COG1609	Transcriptional regulator
ELQ40_RS04880	COG0492	ferredoxin-NADP+ reductase activity
ELQ40_RS04895	COG1929	Belongs to the glycerate kinase type-1 family
ELQ40_RS04910	COG1070	Carbohydrate kinase
ELQ40_RS04915	COG2115	Belongs to the xylose isomerase family
ELQ40_RS04935	COG1472	Belongs to the glycosyl hydrolase 3 family
ELQ40_RS04940	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS04960	COG2814	Major facilitator Superfamily
ELQ40_RS04990	COG3534	alpha-L-arabinofuranosidase
ELQ40_RS05000	COG0277	FAD linked oxidase domain protein
ELQ40_RS05015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ELQ40_RS05020	COG0590	tRNA wobble adenosine to inosine editing
ELQ40_RS05025	COG2252	PERMEase
ELQ40_RS05035	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS05045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ELQ40_RS05050	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ELQ40_RS05060	COG1414	Transcriptional regulator
ELQ40_RS05070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ELQ40_RS05080	COG3257	ureidoglycine aminohydrolase activity
ELQ40_RS05085	COG3622	Belongs to the hyi family
ELQ40_RS05090	COG2084	Dehydrogenase
ELQ40_RS05095	COG3960	tartronate-semialdehyde synthase activity
ELQ40_RS05100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ELQ40_RS05130	COG0315	cyclic pyranopterin monophosphate synthase activity
ELQ40_RS05130	COG0521	Mo-molybdopterin cofactor biosynthetic process
ELQ40_RS05135	COG0314	molybdopterin synthase activity
ELQ40_RS05150	COG0315	cyclic pyranopterin monophosphate synthase activity
ELQ40_RS05185	COG0433	COG0433 Predicted ATPase
ELQ40_RS05230	COG0385	Bile acid
ELQ40_RS05235	COG2072	flavoprotein involved in K transport
ELQ40_RS05245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ELQ40_RS05265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ELQ40_RS05310	COG0745	RESPONSE REGULATOR receiver
ELQ40_RS05325	COG1414	Transcriptional regulator
ELQ40_RS05330	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ELQ40_RS05345	COG0800	Aldolase
ELQ40_RS05355	COG0601	transmembrane transport
ELQ40_RS05370	COG4608	Belongs to the ABC transporter superfamily
ELQ40_RS05375	COG1940	carbohydrate kinase activity
ELQ40_RS05375	COG1846	Transcriptional regulator
ELQ40_RS05380	COG0579	oxidoreductase
ELQ40_RS05385	COG0488	(ABC) transporter
ELQ40_RS05415	COG0489	protein tyrosine kinase activity
ELQ40_RS05420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ELQ40_RS05465	COG1083	cytidylyl-transferase
ELQ40_RS05475	COG2089	acid synthase
ELQ40_RS05480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ELQ40_RS05485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ELQ40_RS05490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ELQ40_RS05495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ELQ40_RS05535	COG0438	transferase activity, transferring glycosyl groups
ELQ40_RS05600	COG1404	Belongs to the peptidase S8 family
ELQ40_RS05615	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ELQ40_RS05630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ELQ40_RS05645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ELQ40_RS05680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ELQ40_RS05680	COG1754	DNA topoisomerase type I activity
ELQ40_RS05685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ELQ40_RS05690	COG0470	DNA polymerase III
ELQ40_RS05715	COG1335	isochorismatase
ELQ40_RS05740	COG1309	transcriptional regulator
ELQ40_RS05770	COG0179	Fumarylacetoacetate (FAA) hydrolase
ELQ40_RS05780	COG3971	2-oxopent-4-enoate hydratase activity
ELQ40_RS05825	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ELQ40_RS05850	COG1132	(ABC) transporter
ELQ40_RS05865	COG2313	pseudouridylate synthase activity
ELQ40_RS05870	COG2319	Wd-40 repeat
ELQ40_RS05870	COG4249	Peptidase C14 caspase catalytic subunit p20
ELQ40_RS05890	COG0505	Belongs to the CarA family
ELQ40_RS05905	COG0477	Major facilitator Superfamily
ELQ40_RS05910	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ELQ40_RS05915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ELQ40_RS05915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ELQ40_RS05935	COG1011	Hydrolase
ELQ40_RS05940	COG0180	Tryptophanyl-tRNA synthetase
ELQ40_RS05970	COG1053	succinate dehydrogenase
ELQ40_RS05980	COG2009	succinate dehydrogenase
ELQ40_RS05990	COG1744	ABC transporter substrate-binding protein PnrA-like
ELQ40_RS06000	COG3845	ABC transporter
ELQ40_RS06005	COG4603	Belongs to the binding-protein-dependent transport system permease family
ELQ40_RS06010	COG1079	Belongs to the binding-protein-dependent transport system permease family
ELQ40_RS06025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ELQ40_RS06030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ELQ40_RS06040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ELQ40_RS06055	COG0531	amino acid
ELQ40_RS06060	COG4770	biotin carboxylase activity
ELQ40_RS06065	COG0424	maF-like protein
ELQ40_RS06070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ELQ40_RS06095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ELQ40_RS06130	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ELQ40_RS06135	COG1316	TRANSCRIPTIONal
ELQ40_RS06140	COG0438	transferase activity, transferring glycosyl groups
ELQ40_RS06155	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ELQ40_RS06195	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ELQ40_RS06205	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ELQ40_RS06235	COG0406	alpha-ribazole phosphatase activity
ELQ40_RS06310	COG1960	acyl-CoA dehydrogenase activity
ELQ40_RS06315	COG1482	cell wall glycoprotein biosynthetic process
ELQ40_RS06325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ELQ40_RS06355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ELQ40_RS06360	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ELQ40_RS06385	COG0714	Associated with various cellular activities
ELQ40_RS06405	COG0745	RESPONSE REGULATOR receiver
ELQ40_RS06410	COG5002	protein histidine kinase activity
ELQ40_RS06410	COG5000	phosphorelay sensor kinase activity
ELQ40_RS06415	COG5401	PFAM Sporulation and spore germination
ELQ40_RS06425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ELQ40_RS06430	COG0653	protein targeting
ELQ40_RS06485	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ELQ40_RS06490	COG1595	DNA-templated transcription, initiation
ELQ40_RS06500	COG2409	Drug exporters of the RND superfamily
ELQ40_RS06505	COG0567	Dehydrogenase, E1 component
ELQ40_RS06505	COG0508	dehydrogenase complex catalyzes the overall conversion of
ELQ40_RS06525	COG1902	pentaerythritol trinitrate reductase activity
ELQ40_RS06550	COG2814	Major facilitator Superfamily
ELQ40_RS06555	COG2197	response regulator
ELQ40_RS06570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ELQ40_RS06590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ELQ40_RS06610	COG0154	amidase activity
ELQ40_RS06615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ELQ40_RS06620	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ELQ40_RS06625	COG1120	ATPase activity
ELQ40_RS06650	COG1842	Phage shock protein A
ELQ40_RS06665	COG1595	DNA-templated transcription, initiation
ELQ40_RS06680	COG1940	carbohydrate kinase activity
ELQ40_RS06690	COG0018	arginyl-trna synthetase
ELQ40_RS06700	COG0019	diaminopimelate decarboxylase activity
ELQ40_RS06705	COG0460	homoserine dehydrogenase
ELQ40_RS06710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ELQ40_RS06715	COG0083	homoserine kinase activity
ELQ40_RS06725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ELQ40_RS06735	COG1045	serine acetyltransferase
ELQ40_RS06745	COG2890	protein-(glutamine-N5) methyltransferase activity
ELQ40_RS06770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ELQ40_RS06780	COG0356	it plays a direct role in the translocation of protons across the membrane
ELQ40_RS06785	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ELQ40_RS06790	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ELQ40_RS06795	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ELQ40_RS06800	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ELQ40_RS06805	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ELQ40_RS06810	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ELQ40_RS06815	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ELQ40_RS06825	COG3022	response to hydroperoxide
ELQ40_RS06830	COG2818	Glycosylase
ELQ40_RS06835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ELQ40_RS06845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ELQ40_RS06850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ELQ40_RS06860	COG1012	belongs to the aldehyde dehydrogenase family
ELQ40_RS06870	COG0631	protein serine/threonine phosphatase activity
ELQ40_RS06885	COG0714	Associated with various cellular activities
ELQ40_RS06915	COG3842	ATPase activity
ELQ40_RS06920	COG1176	ABC-type spermidine putrescine transport system, permease component I
ELQ40_RS06935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ELQ40_RS06950	COG0204	Acyl-transferase
ELQ40_RS06950	COG0318	PFAM AMP-dependent synthetase and ligase
ELQ40_RS06960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ELQ40_RS06965	COG0750	zinc metalloprotease
ELQ40_RS06970	COG3850	Histidine kinase
ELQ40_RS06980	COG0183	Belongs to the thiolase family
ELQ40_RS06995	COG0411	ABC transporter
ELQ40_RS07015	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS07020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ELQ40_RS07040	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ELQ40_RS07045	COG0442	prolyl-tRNA aminoacylation
ELQ40_RS07050	COG1115	amino acid carrier protein
ELQ40_RS07070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ELQ40_RS07095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ELQ40_RS07100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ELQ40_RS07120	COG2807	transmembrane transport
ELQ40_RS07130	COG2390	Transcriptional regulator
ELQ40_RS07135	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ELQ40_RS07145	COG1012	belongs to the aldehyde dehydrogenase family
ELQ40_RS07155	COG0702	epimerase
ELQ40_RS07165	COG1937	Protein conserved in bacteria
ELQ40_RS07175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ELQ40_RS07185	COG1051	belongs to the nudix hydrolase family
ELQ40_RS07200	COG2252	PERMEase
ELQ40_RS07225	COG0179	Fumarylacetoacetate (FAA) hydrolase
ELQ40_RS07235	COG0277	FAD linked oxidase domain protein
ELQ40_RS07250	COG1012	belongs to the aldehyde dehydrogenase family
ELQ40_RS07260	COG0545	Peptidyl-prolyl cis-trans isomerase
ELQ40_RS07275	COG0596	Alpha beta hydrolase
ELQ40_RS07290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ELQ40_RS07290	COG0785	Cytochrome C biogenesis protein
ELQ40_RS07305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ELQ40_RS07335	COG3189	MarR family transcriptional regulator
ELQ40_RS07360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ELQ40_RS07370	COG1573	uracil-dna glycosylase
ELQ40_RS07400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ELQ40_RS07410	COG1215	transferase activity, transferring glycosyl groups
ELQ40_RS07425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ELQ40_RS07455	COG1185	polyribonucleotide nucleotidyltransferase activity
ELQ40_RS07480	COG0022	dehydrogenase e1 component
ELQ40_RS07485	COG0508	dehydrogenase complex catalyzes the overall conversion of
ELQ40_RS07490	COG2154	pterin-4-alpha-carbinolamine dehydratase
ELQ40_RS07495	COG1309	transcriptional regulator
ELQ40_RS07510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ELQ40_RS07520	COG1960	acyl-CoA dehydrogenase activity
ELQ40_RS07525	COG2030	dehydratase
ELQ40_RS07535	COG0667	Aldo Keto reductase
ELQ40_RS07540	COG0612	Peptidase, M16
ELQ40_RS07555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ELQ40_RS07565	COG1090	epimerase
ELQ40_RS07585	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ELQ40_RS07595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ELQ40_RS07600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ELQ40_RS07610	COG0577	efflux transmembrane transporter activity
ELQ40_RS07610	COG1136	(ABC) transporter
ELQ40_RS07615	COG0577	efflux transmembrane transporter activity
ELQ40_RS07620	COG0456	acetyltransferase
ELQ40_RS07630	COG1674	ftsk spoiiie
ELQ40_RS07640	COG1058	Belongs to the CinA family
ELQ40_RS07640	COG1546	Belongs to the CinA family
ELQ40_RS07655	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ELQ40_RS07665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ELQ40_RS07670	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ELQ40_RS07675	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ELQ40_RS07680	COG2890	protein-(glutamine-N5) methyltransferase activity
ELQ40_RS07685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ELQ40_RS07690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ELQ40_RS07700	COG2267	carboxylic ester hydrolase activity
ELQ40_RS07705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ELQ40_RS07710	COG1388	LysM domain
ELQ40_RS07715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ELQ40_RS07720	COG0131	Imidazoleglycerol-phosphate dehydratase
ELQ40_RS07725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ELQ40_RS07730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ELQ40_RS07740	COG0076	glutamate decarboxylase activity
ELQ40_RS07745	COG1201	RNA secondary structure unwinding
ELQ40_RS07750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ELQ40_RS07760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ELQ40_RS07765	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ELQ40_RS07770	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ELQ40_RS07775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ELQ40_RS07780	COG1126	abc transporter atp-binding protein
ELQ40_RS07785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ELQ40_RS07790	COG0765	amino acid transport
ELQ40_RS07795	COG0765	amino acid transport
ELQ40_RS07800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ELQ40_RS07805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ELQ40_RS07805	COG0072	phenylalanine-tRNA ligase activity
ELQ40_RS07815	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ELQ40_RS07820	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ELQ40_RS07825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ELQ40_RS07835	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ELQ40_RS07840	COG0165	Argininosuccinate lyase
ELQ40_RS07845	COG2094	Belongs to the DNA glycosylase MPG family
ELQ40_RS07860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ELQ40_RS07885	COG0647	UMP catabolic process
ELQ40_RS07895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ELQ40_RS07900	COG0497	DNA recombination
ELQ40_RS07905	COG0504	CTP synthase activity
ELQ40_RS07910	COG0494	nUDIX hydrolase
ELQ40_RS07925	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ELQ40_RS07930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ELQ40_RS07945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ELQ40_RS07950	COG1160	GTP binding
ELQ40_RS07960	COG0477	Major facilitator Superfamily
ELQ40_RS07970	COG0028	Belongs to the TPP enzyme family
ELQ40_RS07985	COG1131	(ABC) transporter
ELQ40_RS07990	COG1309	transcriptional regulator
ELQ40_RS08005	COG1253	flavin adenine dinucleotide binding
ELQ40_RS08010	COG0531	amino acid
ELQ40_RS08025	COG0745	RESPONSE REGULATOR receiver
ELQ40_RS08030	COG2205	protein histidine kinase activity
ELQ40_RS08040	COG1121	(ABC) transporter
ELQ40_RS08045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ELQ40_RS08095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ELQ40_RS08125	COG2357	RelA SpoT domain protein
ELQ40_RS08135	COG3012	SEC-C Motif Domain Protein
ELQ40_RS08145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ELQ40_RS08175	COG1716	ATPase activity
ELQ40_RS08215	COG1940	carbohydrate kinase activity
ELQ40_RS08225	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ELQ40_RS08230	COG2815	serine threonine protein kinase
ELQ40_RS08230	COG0515	serine threonine protein kinase
ELQ40_RS08235	COG3942	CHAP domain
ELQ40_RS08235	COG1388	LysM domain
ELQ40_RS08245	COG0142	geranyltranstransferase activity
ELQ40_RS08255	COG2001	Belongs to the MraZ family
ELQ40_RS08260	COG0275	rRNA processing
ELQ40_RS08270	COG0768	penicillin binding
ELQ40_RS08275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ELQ40_RS08285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ELQ40_RS08290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ELQ40_RS08300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ELQ40_RS08305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ELQ40_RS08315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ELQ40_RS08325	COG1799	cell septum assembly
ELQ40_RS08335	COG3599	regulation of cell shape
ELQ40_RS08340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ELQ40_RS08350	COG0587	DNA-directed DNA polymerase activity
ELQ40_RS08355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ELQ40_RS08360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ELQ40_RS08365	COG0167	dihydroorotate dehydrogenase activity
ELQ40_RS08385	COG1174	glycine betaine transport
ELQ40_RS08390	COG1174	glycine betaine transport
ELQ40_RS08415	COG1271	oxidase subunit
ELQ40_RS08420	COG1294	oxidase, subunit
ELQ40_RS08425	COG4988	ABC transporter
ELQ40_RS08430	COG1132	(ABC) transporter
ELQ40_RS08435	COG0512	Glutamine amidotransferase of anthranilate synthase
ELQ40_RS08435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ELQ40_RS08440	COG0495	leucyl-tRNA aminoacylation
ELQ40_RS08455	COG0268	Binds directly to 16S ribosomal RNA
ELQ40_RS08465	COG0481	GTPase activity
ELQ40_RS08470	COG4762	Protein conserved in bacteria
ELQ40_RS08490	COG1420	regulation of RNA biosynthetic process
ELQ40_RS08495	COG0484	heat shock protein binding
ELQ40_RS08505	COG0537	adenosine 5'-monophosphoramidase activity
ELQ40_RS08515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ELQ40_RS08525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ELQ40_RS08530	COG4585	Histidine kinase
ELQ40_RS08535	COG2197	response regulator
ELQ40_RS08540	COG1136	(ABC) transporter
ELQ40_RS08545	COG0577	efflux transmembrane transporter activity
ELQ40_RS08550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ELQ40_RS08560	COG1381	Involved in DNA repair and RecF pathway recombination
ELQ40_RS08565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ELQ40_RS08590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ELQ40_RS08595	COG0442	prolyl-tRNA aminoacylation
ELQ40_RS08605	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ELQ40_RS08610	COG0358	DNA primase activity
ELQ40_RS08620	COG0601	transmembrane transport
ELQ40_RS08660	COG0242	peptide deformylase activity
ELQ40_RS08670	COG0438	transferase activity, transferring glycosyl groups
ELQ40_RS08685	COG3328	transposase activity
ELQ40_RS08690	COG3226	Transcriptional regulator
ELQ40_RS08695	COG0110	maltose O-acetyltransferase activity
ELQ40_RS08725	COG3903	Transcriptional regulator
ELQ40_RS08725	COG3629	intracellular signal transduction
ELQ40_RS08730	COG4221	oxidoreductase activity
ELQ40_RS08735	COG1595	DNA-templated transcription, initiation
ELQ40_RS08750	COG1309	transcriptional regulator
ELQ40_RS08775	COG1175	transmembrane transport
ELQ40_RS08780	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS08790	COG0673	inositol 2-dehydrogenase activity
ELQ40_RS08795	COG3458	cephalosporin-C deacetylase activity
ELQ40_RS08800	COG1609	Transcriptional regulator
ELQ40_RS08815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ELQ40_RS08835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ELQ40_RS08840	COG1695	Transcriptional regulator
ELQ40_RS08875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ELQ40_RS08880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ELQ40_RS08885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ELQ40_RS08900	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ELQ40_RS08920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ELQ40_RS08945	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ELQ40_RS08955	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ELQ40_RS08960	COG0174	glutamine synthetase
ELQ40_RS08975	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ELQ40_RS08980	COG0321	lipoyl(octanoyl) transferase activity
ELQ40_RS08995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ELQ40_RS09000	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ELQ40_RS09010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ELQ40_RS09015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ELQ40_RS09030	COG0187	DNA topoisomerase II activity
ELQ40_RS09035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ELQ40_RS09050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ELQ40_RS09060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ELQ40_RS09065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ELQ40_RS09075	COG2226	methyltransferase
ELQ40_RS09080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ELQ40_RS09085	COG0723	plastoquinol--plastocyanin reductase activity
ELQ40_RS09090	COG2010	Cytochrome c
ELQ40_RS09095	COG1845	cytochrome c oxidase, subunit III
ELQ40_RS09100	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ELQ40_RS09105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ELQ40_RS09110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ELQ40_RS09115	COG2376	Dihydroxyacetone kinase
ELQ40_RS09120	COG1461	Dihydroxyacetone kinase
ELQ40_RS09125	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ELQ40_RS09125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ELQ40_RS09125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ELQ40_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS09165	COG1733	regulation of RNA biosynthetic process
ELQ40_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS09200	COG0584	glycerophosphoryl diester phosphodiesterase
ELQ40_RS09220	COG0805	protein transport
ELQ40_RS09225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ELQ40_RS09260	COG1968	undecaprenyl-diphosphatase activity
ELQ40_RS09265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ELQ40_RS09285	COG0587	DNA-directed DNA polymerase activity
ELQ40_RS09350	COG0254	rRNA binding
ELQ40_RS09355	COG1119	ATPase activity
ELQ40_RS09360	COG0297	glycogen (starch) synthase activity
ELQ40_RS09365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ELQ40_RS09370	COG0560	Phosphoserine phosphatase
ELQ40_RS09370	COG3830	Belongs to the UPF0237 family
ELQ40_RS09395	COG0488	(ABC) transporter
ELQ40_RS09410	COG1472	Belongs to the glycosyl hydrolase 3 family
ELQ40_RS09460	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ELQ40_RS09460	COG1082	Xylose isomerase domain protein TIM barrel
ELQ40_RS09465	COG0028	Belongs to the TPP enzyme family
ELQ40_RS09475	COG1012	belongs to the aldehyde dehydrogenase family
ELQ40_RS09490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ELQ40_RS09495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ELQ40_RS09500	COG1414	Transcriptional regulator
ELQ40_RS09510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ELQ40_RS09515	COG1309	transcriptional regulator
ELQ40_RS09520	COG1414	Transcriptional regulator
ELQ40_RS09525	COG1414	Transcriptional regulator
ELQ40_RS09535	COG2826	transposase and inactivated derivatives, IS30 family
ELQ40_RS09585	COG0799	negative regulation of ribosome biogenesis
ELQ40_RS09600	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ELQ40_RS09610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ELQ40_RS09615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ELQ40_RS09620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ELQ40_RS09625	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ELQ40_RS09630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ELQ40_RS09640	COG1530	ribonuclease E activity
ELQ40_RS09660	COG0285	dihydrofolate synthase activity
ELQ40_RS09665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ELQ40_RS09675	COG0747	negative chemotaxis
ELQ40_RS09685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ELQ40_RS09695	COG0525	valine-tRNA ligase activity
ELQ40_RS09710	COG4106	trans-aconitate 2-methyltransferase activity
ELQ40_RS09715	COG2151	metal-sulfur cluster biosynthetic enzyme
ELQ40_RS09720	COG0396	ATPase activity
ELQ40_RS09730	COG0719	Fe-S assembly protein
ELQ40_RS09745	COG0109	protoheme IX farnesyltransferase activity
ELQ40_RS09755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ELQ40_RS09760	COG0166	Belongs to the GPI family
ELQ40_RS09775	COG0363	glucosamine-6-phosphate deaminase activity
ELQ40_RS09785	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ELQ40_RS09790	COG0149	triose-phosphate isomerase activity
ELQ40_RS09795	COG0126	phosphoglycerate kinase activity
ELQ40_RS09805	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ELQ40_RS09810	COG1481	regulation of sporulation
ELQ40_RS09815	COG1660	Displays ATPase and GTPase activities
ELQ40_RS09820	COG0322	excinuclease ABC activity
ELQ40_RS09830	COG0556	nucleotide-excision repair
ELQ40_RS09835	COG0237	dephospho-CoA kinase activity
ELQ40_RS09840	COG0539	negative regulation of cytoplasmic translation
ELQ40_RS09845	COG1090	epimerase
ELQ40_RS09885	COG0069	glutamate synthase activity
ELQ40_RS09885	COG0067	glutamate synthase
ELQ40_RS09885	COG0070	glutamate synthase
ELQ40_RS09890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ELQ40_RS09895	COG0159	tryptophan synthase activity
ELQ40_RS09900	COG0133	tryptophan synthase activity
ELQ40_RS09905	COG0134	indole-3-glycerol-phosphate synthase activity
ELQ40_RS09925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ELQ40_RS09930	COG0107	imidazoleglycerol-phosphate synthase activity
ELQ40_RS09935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ELQ40_RS09940	COG0140	phosphoribosyl-ATP diphosphatase activity
ELQ40_RS09945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ELQ40_RS09955	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ELQ40_RS09965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ELQ40_RS09975	COG1758	RNA polymerase activity
ELQ40_RS09980	COG0194	GDP metabolic process
ELQ40_RS09985	COG0284	orotidine-5'-phosphate decarboxylase activity
ELQ40_RS09990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ELQ40_RS09995	COG0505	Belongs to the CarA family
ELQ40_RS10005	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ELQ40_RS10010	COG0540	Belongs to the ATCase OTCase family
ELQ40_RS10015	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ELQ40_RS10025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ELQ40_RS10030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ELQ40_RS10035	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ELQ40_RS10040	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ELQ40_RS10045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ELQ40_RS10050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ELQ40_RS10055	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ELQ40_RS10065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ELQ40_RS10070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ELQ40_RS10080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ELQ40_RS10095	COG1196	nuclear chromosome segregation
ELQ40_RS10105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ELQ40_RS10110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ELQ40_RS10115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ELQ40_RS10125	COG2255	four-way junction helicase activity
ELQ40_RS10130	COG0632	four-way junction helicase activity
ELQ40_RS10135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ELQ40_RS10140	COG0217	transcriptional regulatory protein
ELQ40_RS10155	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ELQ40_RS10160	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ELQ40_RS10170	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ELQ40_RS10180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ELQ40_RS10220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ELQ40_RS10245	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ELQ40_RS10250	COG0183	Belongs to the thiolase family
ELQ40_RS10255	COG1024	Enoyl-CoA hydratase
ELQ40_RS10255	COG1250	3-hydroxyacyl-CoA dehydrogenase
ELQ40_RS10260	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ELQ40_RS10265	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ELQ40_RS10280	COG0756	dUTP diphosphatase activity
ELQ40_RS10305	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ELQ40_RS10310	COG0740	serine-type endopeptidase activity
ELQ40_RS10315	COG0740	serine-type endopeptidase activity
ELQ40_RS10325	COG0544	peptidyl-prolyl cis-trans isomerase activity
ELQ40_RS10350	COG0783	Belongs to the Dps family
ELQ40_RS10360	COG2197	response regulator
ELQ40_RS10370	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ELQ40_RS10410	COG4585	Histidine kinase
ELQ40_RS10415	COG2197	response regulator
ELQ40_RS10425	COG0668	transmembrane transport
ELQ40_RS10445	COG1946	Acyl-CoA thioesterase
ELQ40_RS10475	COG0629	single-stranded DNA binding
ELQ40_RS10480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ELQ40_RS10485	COG0667	Aldo Keto reductase
ELQ40_RS10500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ELQ40_RS10505	COG0475	glutathione-regulated potassium exporter activity
ELQ40_RS10515	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ELQ40_RS10550	COG4172	Belongs to the ABC transporter superfamily
ELQ40_RS10555	COG4721	ABC-type cobalt transport system, permease component
ELQ40_RS10565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ELQ40_RS10575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ELQ40_RS10580	COG0154	amidase activity
ELQ40_RS10585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ELQ40_RS10595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ELQ40_RS10605	COG0482	sulfurtransferase activity
ELQ40_RS10630	COG0366	Alpha amylase catalytic
ELQ40_RS10635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ELQ40_RS10685	COG0233	cytoplasmic translational termination
ELQ40_RS10690	COG0528	UMP kinase activity
ELQ40_RS10695	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ELQ40_RS10700	COG0052	Belongs to the universal ribosomal protein uS2 family
ELQ40_RS10710	COG4974	Belongs to the 'phage' integrase family
ELQ40_RS10730	COG0792	nuclease activity
ELQ40_RS10740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ELQ40_RS10745	COG0681	Belongs to the peptidase S26 family
ELQ40_RS10750	COG0335	large ribosomal subunit rRNA binding
ELQ40_RS10760	COG0024	Methionine aminopeptidase
ELQ40_RS10770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ELQ40_RS10775	COG1648	precorrin-2 dehydrogenase activity
ELQ40_RS10775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ELQ40_RS10785	COG2223	nitrite transmembrane transporter activity
ELQ40_RS10795	COG0336	Belongs to the RNA methyltransferase TrmD family
ELQ40_RS10800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ELQ40_RS10805	COG1837	Belongs to the UPF0109 family
ELQ40_RS10810	COG0228	four-way junction DNA binding
ELQ40_RS10815	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ELQ40_RS10880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ELQ40_RS10885	COG0571	ribonuclease III activity
ELQ40_RS10890	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ELQ40_RS10910	COG0714	Associated with various cellular activities
ELQ40_RS10915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ELQ40_RS10920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ELQ40_RS10930	COG0742	ribosomal rna small subunit methyltransferase
ELQ40_RS10950	COG1181	Belongs to the D-alanine--D-alanine ligase family
ELQ40_RS10955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ELQ40_RS10965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ELQ40_RS10970	COG0066	3-isopropylmalate dehydratase activity
ELQ40_RS10975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ELQ40_RS10985	COG1305	Transglutaminase-like
ELQ40_RS10995	COG0714	Associated with various cellular activities
ELQ40_RS11010	COG2815	serine threonine protein kinase
ELQ40_RS11010	COG0515	serine threonine protein kinase
ELQ40_RS11020	COG0631	protein serine/threonine phosphatase activity
ELQ40_RS11045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ELQ40_RS11070	COG1472	Belongs to the glycosyl hydrolase 3 family
ELQ40_RS11080	COG1012	belongs to the aldehyde dehydrogenase family
ELQ40_RS11085	COG1172	Belongs to the binding-protein-dependent transport system permease family
ELQ40_RS11090	COG1129	ABC transporter
ELQ40_RS11095	COG1172	Belongs to the binding-protein-dependent transport system permease family
ELQ40_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS11110	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ELQ40_RS11115	COG1414	Transcriptional regulator
ELQ40_RS11120	COG1942	4-Oxalocrotonate Tautomerase
ELQ40_RS11135	COG1349	DNA-binding transcription factor activity
ELQ40_RS11210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ELQ40_RS11215	COG0583	DNA-binding transcription factor activity
ELQ40_RS11225	COG0179	Fumarylacetoacetate (FAA) hydrolase
ELQ40_RS11235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ELQ40_RS11240	COG0473	3-isopropylmalate dehydrogenase activity
ELQ40_RS11250	COG0477	Major facilitator Superfamily
ELQ40_RS11285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ELQ40_RS11290	COG0440	acetolactate synthase activity
ELQ40_RS11295	COG0028	Belongs to the TPP enzyme family
ELQ40_RS11300	COG0129	dihydroxy-acid dehydratase activity
ELQ40_RS11305	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ELQ40_RS11315	COG1511	domain protein
ELQ40_RS11320	COG2409	Drug exporters of the RND superfamily
ELQ40_RS11340	COG1268	BioY protein
ELQ40_RS11345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ELQ40_RS11350	COG0183	Belongs to the thiolase family
ELQ40_RS11355	COG1122	ATPase activity
ELQ40_RS11370	COG0483	inositol monophosphate 1-phosphatase activity
ELQ40_RS11390	COG0697	spore germination
ELQ40_RS11420	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ELQ40_RS11425	COG2177	Part of the ABC transporter FtsEX involved in
ELQ40_RS11430	COG2884	Cell division ATP-binding protein ftsE
ELQ40_RS11435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ELQ40_RS11540	COG0730	response to heat
ELQ40_RS11570	COG0586	Pfam SNARE associated Golgi protein
ELQ40_RS11580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ELQ40_RS11585	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ELQ40_RS11590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ELQ40_RS11620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ELQ40_RS11660	COG1215	transferase activity, transferring glycosyl groups
ELQ40_RS11665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ELQ40_RS11690	COG0702	epimerase
ELQ40_RS11695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ELQ40_RS11715	COG0446	pyridine nucleotide-disulphide oxidoreductase
ELQ40_RS11735	COG2378	regulation of single-species biofilm formation
ELQ40_RS11745	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS11760	COG1554	hydrolase, family 65, central catalytic
ELQ40_RS11815	COG1615	UPF0182 protein
ELQ40_RS11820	COG3480	Lon protease (S16) C-terminal proteolytic domain
ELQ40_RS11855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ELQ40_RS11875	COG0513	Belongs to the DEAD box helicase family
ELQ40_RS11890	COG0006	proline dipeptidase activity
ELQ40_RS11920	COG2239	Acts as a magnesium transporter
ELQ40_RS11960	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS11970	COG1653	transport
ELQ40_RS11980	COG1609	Transcriptional regulator
ELQ40_RS11985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ELQ40_RS12005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ELQ40_RS12010	COG2171	N-acyltransferase activity
ELQ40_RS12045	COG1024	Enoyl-CoA hydratase
ELQ40_RS12050	COG0739	heme binding
ELQ40_RS12055	COG1217	gtp-binding protein TYPA
ELQ40_RS12065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ELQ40_RS12070	COG0601	transmembrane transport
ELQ40_RS12075	COG4166	transmembrane transport
ELQ40_RS12095	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ELQ40_RS12095	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ELQ40_RS12100	COG0509	glycine decarboxylation via glycine cleavage system
ELQ40_RS12105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ELQ40_RS12115	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ELQ40_RS12120	COG1473	amidohydrolase
ELQ40_RS12135	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ELQ40_RS12140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ELQ40_RS12155	COG0243	molybdopterin cofactor binding
ELQ40_RS12160	COG2814	Major facilitator Superfamily
ELQ40_RS12175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ELQ40_RS12185	COG2890	protein-(glutamine-N5) methyltransferase activity
ELQ40_RS12190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ELQ40_RS12205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ELQ40_RS12230	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ELQ40_RS12235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ELQ40_RS12275	COG0012	GTP binding
ELQ40_RS12330	COG2610	gluconate transmembrane transporter activity
ELQ40_RS12335	COG2084	Dehydrogenase
ELQ40_RS12345	COG1802	Transcriptional regulator
ELQ40_RS12355	COG0191	fructose-bisphosphate aldolase activity
ELQ40_RS12365	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ELQ40_RS12370	COG1570	exodeoxyribonuclease VII activity
ELQ40_RS12375	COG1722	exodeoxyribonuclease VII activity
ELQ40_RS12390	COG0114	fumarate hydratase activity
ELQ40_RS12395	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ELQ40_RS12405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ELQ40_RS12420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ELQ40_RS12425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ELQ40_RS12450	COG1704	LemA family
ELQ40_RS12475	COG0248	Ppx GppA phosphatase
ELQ40_RS12505	COG0148	phosphopyruvate hydratase activity
ELQ40_RS12535	COG0124	histidyl-tRNA synthetase
ELQ40_RS12540	COG1271	oxidase subunit
ELQ40_RS12555	COG1280	lysine exporter protein (LysE YggA)
ELQ40_RS12560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ELQ40_RS12575	COG0328	RNA-DNA hybrid ribonuclease activity
ELQ40_RS12595	COG0193	aminoacyl-tRNA hydrolase activity
ELQ40_RS12600	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ELQ40_RS12610	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ELQ40_RS12615	COG2149	membrane
ELQ40_RS12635	COG0318	PFAM AMP-dependent synthetase and ligase
ELQ40_RS12640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ELQ40_RS12645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ELQ40_RS12660	COG2011	ABC-type metal ion transport system permease component
ELQ40_RS12665	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ELQ40_RS12675	COG0488	(ABC) transporter
ELQ40_RS12685	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ELQ40_RS12690	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ELQ40_RS12695	COG0084	hydrolase, TatD family'
ELQ40_RS12700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ELQ40_RS12720	COG3321	synthase
ELQ40_RS12720	COG0604	alcohol dehydrogenase
ELQ40_RS12720	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS12725	COG1476	TRANSCRIPTIONal
ELQ40_RS12735	COG2076	Multidrug Resistance protein
ELQ40_RS12790	COG1832	CoA-binding protein
ELQ40_RS12815	COG2233	PERMEase
ELQ40_RS12830	COG0656	L-ascorbic acid biosynthetic process
ELQ40_RS12855	COG2985	domain, Protein
ELQ40_RS12855	COG0490	domain, Protein
ELQ40_RS12860	COG0475	glutathione-regulated potassium exporter activity
ELQ40_RS12865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ELQ40_RS12875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ELQ40_RS12890	COG0477	Major facilitator Superfamily
ELQ40_RS12915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ELQ40_RS12930	COG1970	mechanosensitive ion channel activity
ELQ40_RS12940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ELQ40_RS12940	COG0425	Belongs to the sulfur carrier protein TusA family
ELQ40_RS12945	COG0686	Belongs to the AlaDH PNT family
ELQ40_RS12955	COG1793	dna ligase
ELQ40_RS12985	COG1388	LysM domain
ELQ40_RS12985	COG3942	CHAP domain
ELQ40_RS13015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ELQ40_RS13030	COG1278	Cold shock
ELQ40_RS13045	COG1061	Type III restriction enzyme res subunit
ELQ40_RS13065	COG0745	RESPONSE REGULATOR receiver
ELQ40_RS13070	COG2205	protein histidine kinase activity
ELQ40_RS13080	COG0459	protein refolding
ELQ40_RS13085	COG1470	cell adhesion involved in biofilm formation
ELQ40_RS13090	COG1278	Cold shock
ELQ40_RS13105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ELQ40_RS13130	COG3842	ATPase activity
ELQ40_RS13140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ELQ40_RS13145	COG0215	cysteine-tRNA ligase activity
ELQ40_RS13165	COG0745	RESPONSE REGULATOR receiver
ELQ40_RS13170	COG5002	protein histidine kinase activity
ELQ40_RS13180	COG0588	phosphoglycerate mutase activity
ELQ40_RS13195	COG3485	protocatechuate 3,4-dioxygenase
ELQ40_RS13205	COG0745	RESPONSE REGULATOR receiver
ELQ40_RS13210	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ELQ40_RS13235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ELQ40_RS13270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ELQ40_RS13280	COG2017	converts alpha-aldose to the beta-anomer
ELQ40_RS13285	COG1349	DNA-binding transcription factor activity
ELQ40_RS13295	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ELQ40_RS13305	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ELQ40_RS13310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ELQ40_RS13340	COG2089	acid synthase
ELQ40_RS13345	COG1083	cytidylyl-transferase
ELQ40_RS13350	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ELQ40_RS13355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ELQ40_RS13385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ELQ40_RS13405	COG1349	DNA-binding transcription factor activity
ELQ40_RS13410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ELQ40_RS13450	COG1472	Belongs to the glycosyl hydrolase 3 family
ELQ40_RS13455	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS13460	COG1175	transmembrane transport
ELQ40_RS13475	COG0538	isocitrate dehydrogenase activity
ELQ40_RS13495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ELQ40_RS13500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ELQ40_RS13505	COG0860	N-Acetylmuramoyl-L-alanine amidase
ELQ40_RS13505	COG2247	cell wall binding repeat
ELQ40_RS13530	COG2197	response regulator
ELQ40_RS13535	COG1752	Esterase of the alpha-beta hydrolase superfamily
ELQ40_RS13535	COG1752	Esterase of the alpha-beta hydrolase superfamily
ELQ40_RS13540	COG1132	(ABC) transporter
ELQ40_RS13550	COG1834	amidinotransferase
ELQ40_RS13560	COG0138	bifunctional purine biosynthesis protein purh
ELQ40_RS13600	COG0045	succinate-CoA ligase (ADP-forming) activity
ELQ40_RS13605	COG1476	TRANSCRIPTIONal
ELQ40_RS13615	COG1131	(ABC) transporter
ELQ40_RS13625	COG0494	nUDIX hydrolase
ELQ40_RS13640	COG2211	Major facilitator Superfamily
ELQ40_RS13650	COG2197	response regulator
ELQ40_RS13685	COG0584	glycerophosphoryl diester phosphodiesterase
ELQ40_RS13695	COG4941	Belongs to the sigma-70 factor family
ELQ40_RS13705	COG0039	L-malate dehydrogenase activity
ELQ40_RS13710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ELQ40_RS13710	COG0519	Catalyzes the synthesis of GMP from XMP
ELQ40_RS13735	COG0490	domain, Protein
ELQ40_RS13740	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ELQ40_RS13745	COG0516	GMP reductase activity
ELQ40_RS13760	COG0488	(ABC) transporter
ELQ40_RS13815	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ELQ40_RS13840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ELQ40_RS13845	COG0454	-acetyltransferase
ELQ40_RS13845	COG0456	acetyltransferase
ELQ40_RS13855	COG0802	atpase or kinase
ELQ40_RS13860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ELQ40_RS13865	COG0736	holo-[acyl-carrier-protein] synthase activity
ELQ40_RS13870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ELQ40_RS13875	COG1072	(Pantothenic acid kinase))
ELQ40_RS13880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ELQ40_RS13885	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ELQ40_RS13890	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ELQ40_RS13895	COG0101	tRNA pseudouridine synthase activity
ELQ40_RS13900	COG0203	ribosomal protein L17
ELQ40_RS13905	COG0202	RNA polymerase activity
ELQ40_RS13910	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ELQ40_RS13915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ELQ40_RS13925	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ELQ40_RS13930	COG0246	Mannitol dehydrogenase
ELQ40_RS13935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ELQ40_RS13945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ELQ40_RS13950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ELQ40_RS13970	COG0563	adenylate kinase activity
ELQ40_RS13980	COG0200	Binds to the 23S rRNA
ELQ40_RS13985	COG1841	ribosomal large subunit assembly
ELQ40_RS13990	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ELQ40_RS13995	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ELQ40_RS14000	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ELQ40_RS14005	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ELQ40_RS14010	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ELQ40_RS14015	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ELQ40_RS14020	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ELQ40_RS14025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ELQ40_RS14030	COG0255	Belongs to the universal ribosomal protein uL29 family
ELQ40_RS14035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ELQ40_RS14040	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ELQ40_RS14045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ELQ40_RS14050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ELQ40_RS14055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ELQ40_RS14060	COG0089	rRNA binding
ELQ40_RS14065	COG0088	Forms part of the polypeptide exit tunnel
ELQ40_RS14070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ELQ40_RS14075	COG0051	transcription antitermination factor activity, RNA binding
ELQ40_RS14090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ELQ40_RS14095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ELQ40_RS14100	COG0049	tRNA binding
ELQ40_RS14105	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ELQ40_RS14220	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ELQ40_RS14240	COG1459	type II secretion system
ELQ40_RS14250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ELQ40_RS14255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ELQ40_RS14260	COG0085	RNA polymerase activity
ELQ40_RS14280	COG1649	PFAM Uncharacterised BCR, COG1649
ELQ40_RS14285	COG1984	allophanate hydrolase subunit 2
ELQ40_RS14290	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ELQ40_RS14295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ELQ40_RS14340	COG0513	Belongs to the DEAD box helicase family
ELQ40_RS14405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ELQ40_RS14405	COG0519	Catalyzes the synthesis of GMP from XMP
ELQ40_RS14445	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ELQ40_RS14460	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ELQ40_RS14470	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ELQ40_RS14485	COG0444	Belongs to the ABC transporter superfamily
ELQ40_RS14510	COG4948	Mandelate Racemase Muconate Lactonizing
ELQ40_RS14515	COG2508	Transcriptional regulator
ELQ40_RS14515	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ELQ40_RS14530	COG3655	Transcriptional regulator
ELQ40_RS14545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ELQ40_RS14550	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ELQ40_RS14555	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ELQ40_RS14580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ELQ40_RS14585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ELQ40_RS14590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ELQ40_RS14595	COG0302	gtp cyclohydrolase
ELQ40_RS14600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ELQ40_RS14620	COG0037	tRNA processing
ELQ40_RS14625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ELQ40_RS14635	COG0739	heme binding
ELQ40_RS14635	COG0741	lytic transglycosylase activity
ELQ40_RS14635	COG1196	nuclear chromosome segregation
ELQ40_RS14745	COG1278	Cold shock
ELQ40_RS14765	COG0697	spore germination
ELQ40_RS14770	COG0596	Alpha beta hydrolase
ELQ40_RS14785	COG0039	L-malate dehydrogenase activity
ELQ40_RS14810	COG0514	ATP-dependent DNA helicase (RecQ)
ELQ40_RS14815	COG1525	nuclease
ELQ40_RS14815	COG4085	toxin activity
ELQ40_RS14815	COG0737	Belongs to the 5'-nucleotidase family
ELQ40_RS14825	COG4581	dead DEAH box helicase
ELQ40_RS14850	COG0738	Major facilitator superfamily
ELQ40_RS14875	COG0640	Transcriptional regulator
ELQ40_RS14880	COG2268	Band 7 protein
ELQ40_RS14880	COG2268	Band 7 protein
ELQ40_RS14900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ELQ40_RS14915	COG1737	Transcriptional regulator
ELQ40_RS14920	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ELQ40_RS14925	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ELQ40_RS14930	COG1472	Belongs to the glycosyl hydrolase 3 family
ELQ40_RS14935	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS14940	COG1175	transmembrane transport
ELQ40_RS14960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ELQ40_RS14965	COG1960	acyl-CoA dehydrogenase activity
ELQ40_RS15000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ELQ40_RS15020	COG0183	Belongs to the thiolase family
ELQ40_RS15025	COG1960	acyl-CoA dehydrogenase activity
ELQ40_RS15055	COG1960	acyl-CoA dehydrogenase activity
ELQ40_RS15060	COG0318	PFAM AMP-dependent synthetase and ligase
ELQ40_RS15100	COG1309	transcriptional regulator
ELQ40_RS15105	COG1028	Short-chain dehydrogenase reductase Sdr
ELQ40_RS15120	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS15140	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ELQ40_RS15150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ELQ40_RS15160	COG4941	Belongs to the sigma-70 factor family
ELQ40_RS15165	COG3795	YCII-related domain
ELQ40_RS15170	COG0702	epimerase
ELQ40_RS15225	COG2197	response regulator
ELQ40_RS15230	COG4585	Histidine kinase
ELQ40_RS15280	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ELQ40_RS15395	COG1301	dicarboxylic acid transport
ELQ40_RS15430	COG1132	(ABC) transporter
ELQ40_RS15460	COG2326	polyphosphate kinase activity
ELQ40_RS15465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ELQ40_RS15480	COG2066	Belongs to the glutaminase family
ELQ40_RS15485	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ELQ40_RS15490	COG0352	thiamine-phosphate diphosphorylase activity
ELQ40_RS15495	COG0352	thiamine-phosphate diphosphorylase activity
ELQ40_RS15495	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ELQ40_RS15495	COG0351	phosphomethylpyrimidine kinase
ELQ40_RS15500	COG0477	Major facilitator Superfamily
ELQ40_RS15520	COG0384	phenazine biosynthesis protein PhzF
ELQ40_RS15550	COG0740	serine-type endopeptidase activity
ELQ40_RS15555	COG0740	serine-type endopeptidase activity
ELQ40_RS15580	COG0789	Transcriptional regulator
ELQ40_RS15585	COG4977	sequence-specific DNA binding
ELQ40_RS15595	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS15600	COG1175	transmembrane transport
ELQ40_RS15605	COG1653	transport
ELQ40_RS15620	COG2826	transposase and inactivated derivatives, IS30 family
ELQ40_RS15640	COG1501	Belongs to the glycosyl hydrolase 31 family
ELQ40_RS15645	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS15650	COG1175	transmembrane transport
ELQ40_RS15660	COG1609	Transcriptional regulator
ELQ40_RS15670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ELQ40_RS15675	COG4129	membrane
ELQ40_RS15685	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ELQ40_RS15725	COG2501	S4 domain
ELQ40_RS15730	COG0154	amidase activity
ELQ40_RS15735	COG2957	Belongs to the agmatine deiminase family
ELQ40_RS15790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ELQ40_RS15810	COG1122	ATPase activity
ELQ40_RS15815	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ELQ40_RS15830	COG0545	Peptidyl-prolyl cis-trans isomerase
ELQ40_RS15845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ELQ40_RS15845	COG2111	Na H antiporter
ELQ40_RS15850	COG1006	Multisubunit Na H antiporter MnhC subunit
ELQ40_RS15855	COG0651	ATP synthesis coupled electron transport
ELQ40_RS15880	COG1250	3-hydroxyacyl-CoA dehydrogenase
ELQ40_RS15880	COG1024	Enoyl-CoA hydratase
ELQ40_RS15885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ELQ40_RS15890	COG2151	metal-sulfur cluster biosynthetic enzyme
ELQ40_RS15895	COG3396	Phenylacetate-CoA oxygenase
ELQ40_RS15900	COG3460	Phenylacetate-CoA oxygenase
ELQ40_RS15905	COG3396	Phenylacetate-CoA oxygenase
ELQ40_RS15920	COG1309	transcriptional regulator
ELQ40_RS15935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ELQ40_RS15950	COG2030	dehydratase
ELQ40_RS15950	COG1012	belongs to the aldehyde dehydrogenase family
ELQ40_RS15955	COG1250	3-hydroxyacyl-CoA dehydrogenase
ELQ40_RS15960	COG1024	Enoyl-CoA hydratase
ELQ40_RS15965	COG0183	Belongs to the thiolase family
ELQ40_RS15970	COG0477	Major facilitator Superfamily
ELQ40_RS15980	COG0514	ATP-dependent DNA helicase (RecQ)
ELQ40_RS15990	COG2205	protein histidine kinase activity
ELQ40_RS15995	COG0745	RESPONSE REGULATOR receiver
ELQ40_RS16010	COG3537	Alpha-1,2-mannosidase
ELQ40_RS16025	COG0513	Belongs to the DEAD box helicase family
ELQ40_RS16035	COG3093	addiction module antidote protein HigA
ELQ40_RS16040	COG4585	Histidine kinase
ELQ40_RS16045	COG2197	response regulator
ELQ40_RS16055	COG0456	acetyltransferase
ELQ40_RS16065	COG0789	Transcriptional regulator
ELQ40_RS16070	COG0667	Aldo Keto reductase
ELQ40_RS16090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ELQ40_RS16095	COG0402	S-adenosylhomocysteine deaminase activity
ELQ40_RS16105	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ELQ40_RS16120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ELQ40_RS16125	COG2161	toxin-antitoxin pair type II binding
ELQ40_RS16150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ELQ40_RS16155	COG1116	anion transmembrane transporter activity
ELQ40_RS16155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ELQ40_RS16165	COG2351	hydroxyisourate hydrolase activity
ELQ40_RS16215	COG0586	Pfam SNARE associated Golgi protein
ELQ40_RS16235	COG0741	lytic transglycosylase activity
ELQ40_RS16235	COG0739	heme binding
ELQ40_RS16235	COG1196	nuclear chromosome segregation
ELQ40_RS16240	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ELQ40_RS16245	COG1228	amidohydrolase
ELQ40_RS16270	COG2217	Heavy metal translocating P-type atpase
ELQ40_RS16275	COG2188	Transcriptional regulator
ELQ40_RS16290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ELQ40_RS16310	COG2364	Membrane
ELQ40_RS16330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ELQ40_RS16335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ELQ40_RS16350	COG0531	amino acid
ELQ40_RS16355	COG2267	carboxylic ester hydrolase activity
ELQ40_RS16365	COG3938	Belongs to the proline racemase family
ELQ40_RS16370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ELQ40_RS16375	COG0446	pyridine nucleotide-disulphide oxidoreductase
ELQ40_RS16390	COG1802	Transcriptional regulator
ELQ40_RS16395	COG0006	proline dipeptidase activity
ELQ40_RS16405	COG4608	Belongs to the ABC transporter superfamily
ELQ40_RS16410	COG0444	Belongs to the ABC transporter superfamily
ELQ40_RS16420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ELQ40_RS16425	COG0747	negative chemotaxis
ELQ40_RS16460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ELQ40_RS16470	COG2050	protein possibly involved in aromatic compounds catabolism
ELQ40_RS16480	COG1522	sequence-specific DNA binding
ELQ40_RS16490	COG0022	dehydrogenase e1 component
ELQ40_RS16505	COG1280	lysine exporter protein (LysE YggA)
ELQ40_RS16510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ELQ40_RS16515	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ELQ40_RS16545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ELQ40_RS16550	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ELQ40_RS16565	COG0151	Belongs to the GarS family
ELQ40_RS16570	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ELQ40_RS16575	COG2514	catechol 2,3-dioxygenase activity
ELQ40_RS16585	COG3483	tryptophan 2,3-dioxygenase activity
ELQ40_RS16610	COG3655	Transcriptional regulator
ELQ40_RS16620	COG1403	HNH endonuclease
ELQ40_RS16640	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ELQ40_RS16645	COG0047	phosphoribosylformylglycinamidine synthase activity
ELQ40_RS16670	COG3119	arylsulfatase activity
ELQ40_RS16695	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ELQ40_RS16700	COG2814	Major facilitator Superfamily
ELQ40_RS16710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ELQ40_RS16750	COG1404	Belongs to the peptidase S8 family
ELQ40_RS16760	COG4221	oxidoreductase activity
ELQ40_RS16765	COG1605	Chorismate mutase
ELQ40_RS16765	COG0287	Prephenate dehydrogenase
ELQ40_RS16775	COG1136	(ABC) transporter
ELQ40_RS16775	COG0577	efflux transmembrane transporter activity
ELQ40_RS16780	COG3397	chitin binding
ELQ40_RS16790	COG1131	(ABC) transporter
ELQ40_RS16795	COG1725	Transcriptional regulator
ELQ40_RS16825	COG1595	DNA-templated transcription, initiation
ELQ40_RS16850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ELQ40_RS16880	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ELQ40_RS16895	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ELQ40_RS16905	COG3275	phosphorelay sensor kinase activity
ELQ40_RS16920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ELQ40_RS16945	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ELQ40_RS16955	COG0137	argininosuccinate synthase activity
ELQ40_RS16960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ELQ40_RS16965	COG0598	Magnesium transport protein CorA
ELQ40_RS16995	COG0673	inositol 2-dehydrogenase activity
ELQ40_RS17005	COG4948	Mandelate Racemase Muconate Lactonizing
ELQ40_RS17010	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS17015	COG4209	transmembrane transport
ELQ40_RS17025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ELQ40_RS17080	COG2897	thiosulfate sulfurtransferase activity
ELQ40_RS17090	COG1362	aminopeptidase activity
ELQ40_RS17095	COG0484	heat shock protein binding
ELQ40_RS17100	COG2186	Transcriptional regulator
ELQ40_RS17105	COG0657	acetylesterase activity
ELQ40_RS17135	COG1331	Highly conserved protein containing a thioredoxin domain
ELQ40_RS17160	COG1643	Atp-dependent helicase
ELQ40_RS17180	COG4172	Belongs to the ABC transporter superfamily
ELQ40_RS17185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ELQ40_RS17205	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ELQ40_RS17205	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ELQ40_RS17215	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ELQ40_RS17240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ELQ40_RS17245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ELQ40_RS17255	COG1116	anion transmembrane transporter activity
ELQ40_RS17260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ELQ40_RS17270	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ELQ40_RS17285	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ELQ40_RS17300	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ELQ40_RS17335	COG0251	oxidation-reduction process
ELQ40_RS17340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ELQ40_RS17345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ELQ40_RS17355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ELQ40_RS17360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ELQ40_RS17375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ELQ40_RS17380	COG1120	ATPase activity
ELQ40_RS17385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ELQ40_RS17410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ELQ40_RS17430	COG1920	GTP binding
ELQ40_RS17440	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
ELQ40_RS17440	COG0778	Nitroreductase
ELQ40_RS17460	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ELQ40_RS17475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ELQ40_RS17490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ELQ40_RS17535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ELQ40_RS17555	COG0277	FAD linked oxidase domain protein
ELQ40_RS17590	COG4585	Histidine kinase
ELQ40_RS17595	COG2197	response regulator
ELQ40_RS17610	COG0662	Cupin 2, conserved barrel domain protein
ELQ40_RS17615	COG4152	abc transporter atp-binding protein
ELQ40_RS17665	COG2272	Belongs to the type-B carboxylesterase lipase family
ELQ40_RS17675	COG0542	response to heat
ELQ40_RS17680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ELQ40_RS17695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ELQ40_RS17735	COG0477	Major facilitator Superfamily
ELQ40_RS17740	COG2197	response regulator
ELQ40_RS17750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ELQ40_RS17760	COG0628	permease
ELQ40_RS17765	COG0628	permease
ELQ40_RS17800	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ELQ40_RS17805	COG2813	Specifically methylates the guanine in position
ELQ40_RS17815	COG1309	transcriptional regulator
ELQ40_RS17825	COG0789	Transcriptional regulator
ELQ40_RS17830	COG0484	heat shock protein binding
ELQ40_RS17835	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ELQ40_RS17840	COG0443	Heat shock 70 kDa protein
ELQ40_RS17870	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ELQ40_RS17875	COG0701	Predicted permease
ELQ40_RS17895	COG0346	lactoylglutathione lyase activity
ELQ40_RS17905	COG2815	serine threonine protein kinase
ELQ40_RS17905	COG0515	serine threonine protein kinase
ELQ40_RS17925	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ELQ40_RS17945	COG0175	sulfate reduction
ELQ40_RS17965	COG1116	anion transmembrane transporter activity
ELQ40_RS17970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ELQ40_RS17975	COG1648	precorrin-2 dehydrogenase activity
ELQ40_RS17975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ELQ40_RS17990	COG1472	Belongs to the glycosyl hydrolase 3 family
ELQ40_RS17995	COG0395	ABC-type sugar transport system, permease component
ELQ40_RS18000	COG1175	transmembrane transport
ELQ40_RS18010	COG1609	Transcriptional regulator
ELQ40_RS18030	COG4608	Belongs to the ABC transporter superfamily
ELQ40_RS18035	COG0601	transmembrane transport
ELQ40_RS18040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ELQ40_RS18045	COG0444	Belongs to the ABC transporter superfamily
ELQ40_RS18070	COG1177	transmembrane transport
ELQ40_RS18075	COG1176	ABC-type spermidine putrescine transport system, permease component I
ELQ40_RS18080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ELQ40_RS18085	COG3842	ATPase activity
ELQ40_RS18120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ELQ40_RS18120	COG0723	plastoquinol--plastocyanin reductase activity
ELQ40_RS18125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ELQ40_RS18140	COG0717	Belongs to the dCTP deaminase family
ELQ40_RS18160	COG4106	trans-aconitate 2-methyltransferase activity
ELQ40_RS18170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ELQ40_RS18175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ELQ40_RS18185	COG3336	cytochrome c oxidase
ELQ40_RS18190	COG0776	regulation of translation
ELQ40_RS18195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ELQ40_RS18200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ELQ40_RS18205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ELQ40_RS18230	COG0076	glutamate decarboxylase activity
ELQ40_RS18245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ELQ40_RS18250	COG1121	(ABC) transporter
ELQ40_RS18255	COG0803	Belongs to the bacterial solute-binding protein 9 family
ELQ40_RS18265	COG0508	dehydrogenase complex catalyzes the overall conversion of
ELQ40_RS18270	COG0022	dehydrogenase e1 component
ELQ40_RS18280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ELQ40_RS18285	COG1950	PFAM Membrane protein of
ELQ40_RS18310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ELQ40_RS18315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ELQ40_RS18335	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ELQ40_RS18355	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ELQ40_RS18360	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ELQ40_RS18370	COG1414	Transcriptional regulator
ELQ40_RS18425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ELQ40_RS18435	COG0492	ferredoxin-NADP+ reductase activity
ELQ40_RS18440	COG0534	Mate efflux family protein
ELQ40_RS18445	COG1215	transferase activity, transferring glycosyl groups
ELQ40_RS18510	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ELQ40_RS18525	COG2860	membrane
ELQ40_RS18530	COG0596	Alpha beta hydrolase
ELQ40_RS18540	COG0305	Participates in initiation and elongation during chromosome replication
ELQ40_RS18550	COG0359	binds to the 23S rRNA
ELQ40_RS18555	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ELQ40_RS18565	COG0360	Binds together with S18 to 16S ribosomal RNA
ELQ40_RS18570	COG0617	tRNA 3'-terminal CCA addition
ELQ40_RS18585	COG0492	ferredoxin-NADP+ reductase activity
ELQ40_RS18590	COG3118	belongs to the thioredoxin family
ELQ40_RS18595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ELQ40_RS18605	COG1475	DNA binding
ELQ40_RS18610	COG1192	Involved in chromosome partitioning
ELQ40_RS18615	COG0357	Ribosomal RNA small subunit methyltransferase G
ELQ40_RS18625	COG0706	membrane insertase activity
ELQ40_RS18630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ELQ40_RS18635	COG0594	ribonuclease P activity
ELQ40_RS18640	COG0230	Belongs to the bacterial ribosomal protein bL34 family