locus-tag	class	description
KDJ95_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KDJ95_RS00010	COG1131	(ABC) transporter
KDJ95_RS00030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KDJ95_RS00035	COG0564	pseudouridine synthase activity
KDJ95_RS00050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KDJ95_RS00055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KDJ95_RS00065	COG0513	Belongs to the DEAD box helicase family
KDJ95_RS00075	COG0673	inositol 2-dehydrogenase activity
KDJ95_RS00095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KDJ95_RS00110	COG1971	Probably functions as a manganese efflux pump
KDJ95_RS00135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KDJ95_RS00160	COG0442	prolyl-tRNA aminoacylation
KDJ95_RS00185	COG0531	amino acid
KDJ95_RS00190	COG2066	Belongs to the glutaminase family
KDJ95_RS00200	COG1115	amino acid carrier protein
KDJ95_RS00210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KDJ95_RS00215	COG2890	protein-(glutamine-N5) methyltransferase activity
KDJ95_RS00220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KDJ95_RS00225	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KDJ95_RS00240	COG2226	methyltransferase
KDJ95_RS00245	COG0534	Mate efflux family protein
KDJ95_RS00255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KDJ95_RS00260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KDJ95_RS00265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KDJ95_RS00270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KDJ95_RS00275	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KDJ95_RS00290	COG1121	(ABC) transporter
KDJ95_RS00295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KDJ95_RS00300	COG3880	PFAM UvrB UvrC protein
KDJ95_RS00305	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KDJ95_RS00310	COG0542	response to heat
KDJ95_RS00340	COG0179	Fumarylacetoacetate (FAA) hydrolase
KDJ95_RS00345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KDJ95_RS00360	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KDJ95_RS00360	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KDJ95_RS00370	COG0180	Tryptophanyl-tRNA synthetase
KDJ95_RS00380	COG1692	metallophosphoesterase
KDJ95_RS00385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KDJ95_RS00400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KDJ95_RS00405	COG2816	NAD+ diphosphatase activity
KDJ95_RS00410	COG0156	8-amino-7-oxononanoate synthase activity
KDJ95_RS00425	COG0515	serine threonine protein kinase
KDJ95_RS00425	COG3266	domain, Protein
KDJ95_RS00465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KDJ95_RS00475	COG3189	MarR family transcriptional regulator
KDJ95_RS00480	COG0181	hydroxymethylbilane synthase activity
KDJ95_RS00485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KDJ95_RS00495	COG1469	GTP cyclohydrolase I activity
KDJ95_RS00500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KDJ95_RS00505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KDJ95_RS00510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KDJ95_RS00515	COG1940	carbohydrate kinase activity
KDJ95_RS00530	COG0494	nUDIX hydrolase
KDJ95_RS00535	COG1566	PFAM secretion protein HlyD family protein
KDJ95_RS00540	COG0577	efflux transmembrane transporter activity
KDJ95_RS00540	COG1136	(ABC) transporter
KDJ95_RS00545	COG0577	efflux transmembrane transporter activity
KDJ95_RS00545	COG1136	(ABC) transporter
KDJ95_RS00550	COG1538	Outer membrane efflux protein
KDJ95_RS00565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KDJ95_RS00575	COG1720	tRNA m6t6A37 methyltransferase activity
KDJ95_RS00580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KDJ95_RS00585	COG0540	Belongs to the ATCase OTCase family
KDJ95_RS00590	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KDJ95_RS00605	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KDJ95_RS00610	COG2957	Belongs to the agmatine deiminase family
KDJ95_RS00620	COG0750	zinc metalloprotease
KDJ95_RS00630	COG3119	arylsulfatase activity
KDJ95_RS00640	COG1918	ferrous iron import across plasma membrane
KDJ95_RS00640	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KDJ95_RS00690	COG1475	DNA binding
KDJ95_RS00725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KDJ95_RS00735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KDJ95_RS00740	COG0601	transmembrane transport
KDJ95_RS00795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KDJ95_RS00800	COG1132	(ABC) transporter
KDJ95_RS00805	COG1132	(ABC) transporter
KDJ95_RS00820	COG1127	ABC transporter
KDJ95_RS00825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KDJ95_RS00855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KDJ95_RS00870	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KDJ95_RS00875	COG0504	CTP synthase activity
KDJ95_RS00880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KDJ95_RS00905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KDJ95_RS00915	COG1322	Protein conserved in bacteria
KDJ95_RS00920	COG0546	phosphoglycolate phosphatase activity
KDJ95_RS00925	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KDJ95_RS00935	COG4591	ABC-type transport system involved in lipoprotein release permease component
KDJ95_RS00960	COG2234	aminopeptidase activity
KDJ95_RS00965	COG0657	acetylesterase activity
KDJ95_RS00965	COG2755	lipolytic protein G-D-S-L family
KDJ95_RS00970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KDJ95_RS00990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KDJ95_RS00995	COG2267	carboxylic ester hydrolase activity
KDJ95_RS01005	COG0335	large ribosomal subunit rRNA binding
KDJ95_RS01015	COG0346	lactoylglutathione lyase activity
KDJ95_RS01030	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KDJ95_RS01035	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KDJ95_RS01040	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KDJ95_RS01040	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KDJ95_RS01045	COG0427	acetyl-CoA hydrolase
KDJ95_RS01055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KDJ95_RS01065	COG0205	6-phosphofructokinase activity
KDJ95_RS01075	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KDJ95_RS01080	COG0028	Belongs to the TPP enzyme family
KDJ95_RS01100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KDJ95_RS01115	COG0471	metal ion transport
KDJ95_RS01125	COG0351	phosphomethylpyrimidine kinase
KDJ95_RS01175	COG1028	Short-chain dehydrogenase reductase Sdr
KDJ95_RS01185	COG0242	peptide deformylase activity
KDJ95_RS01190	COG1063	alcohol dehydrogenase
KDJ95_RS01200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KDJ95_RS01205	COG1393	Belongs to the ArsC family
KDJ95_RS01210	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KDJ95_RS01215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KDJ95_RS01225	COG1187	pseudouridine synthase activity
KDJ95_RS01235	COG0336	Belongs to the RNA methyltransferase TrmD family
KDJ95_RS01250	COG0539	negative regulation of cytoplasmic translation
KDJ95_RS01295	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KDJ95_RS01300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KDJ95_RS01305	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KDJ95_RS01310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KDJ95_RS01350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KDJ95_RS01370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KDJ95_RS01370	COG0662	Cupin 2, conserved barrel domain protein
KDJ95_RS01380	COG0416	fatty acid biosynthetic process
KDJ95_RS01385	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KDJ95_RS01395	COG0537	adenosine 5'-monophosphoramidase activity
KDJ95_RS01400	COG0009	L-threonylcarbamoyladenylate synthase
KDJ95_RS01405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KDJ95_RS01410	COG0228	four-way junction DNA binding
KDJ95_RS01435	COG1862	Preprotein translocase
KDJ95_RS01440	COG0343	queuine tRNA-ribosyltransferase activity
KDJ95_RS01445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KDJ95_RS01455	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KDJ95_RS01460	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KDJ95_RS01465	COG0776	regulation of translation
KDJ95_RS01495	COG0811	peptide transport
KDJ95_RS01510	COG3250	beta-galactosidase activity
KDJ95_RS01515	COG0525	valine-tRNA ligase activity
KDJ95_RS01525	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KDJ95_RS01530	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KDJ95_RS01535	COG0255	Belongs to the universal ribosomal protein uL29 family
KDJ95_RS01540	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KDJ95_RS01545	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KDJ95_RS01550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KDJ95_RS01560	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KDJ95_RS01565	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KDJ95_RS01570	COG0089	rRNA binding
KDJ95_RS01575	COG0088	Forms part of the polypeptide exit tunnel
KDJ95_RS01580	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KDJ95_RS01585	COG0051	transcription antitermination factor activity, RNA binding
KDJ95_RS01590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KDJ95_RS01595	COG0049	tRNA binding
KDJ95_RS01600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KDJ95_RS01605	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KDJ95_RS01615	COG3852	Histidine kinase
KDJ95_RS01620	COG2204	response regulator
KDJ95_RS01630	COG1722	exodeoxyribonuclease VII activity
KDJ95_RS01635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KDJ95_RS01650	COG0795	lipopolysaccharide-transporting ATPase activity
KDJ95_RS01655	COG1160	GTP binding
KDJ95_RS01660	COG0444	Belongs to the ABC transporter superfamily
KDJ95_RS01730	COG1136	(ABC) transporter
KDJ95_RS01730	COG0577	efflux transmembrane transporter activity
KDJ95_RS01740	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KDJ95_RS01785	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KDJ95_RS01790	COG0799	negative regulation of ribosome biogenesis
KDJ95_RS01795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KDJ95_RS01845	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KDJ95_RS01860	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KDJ95_RS01870	COG0300	oxidoreductase activity
KDJ95_RS01890	COG0038	chloride channel
KDJ95_RS01900	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KDJ95_RS01915	COG0076	glutamate decarboxylase activity
KDJ95_RS01930	COG0167	dihydroorotate dehydrogenase activity
KDJ95_RS01935	COG0352	thiamine-phosphate diphosphorylase activity
KDJ95_RS01955	COG1253	flavin adenine dinucleotide binding
KDJ95_RS01960	COG1253	flavin adenine dinucleotide binding
KDJ95_RS01965	COG1185	polyribonucleotide nucleotidyltransferase activity
KDJ95_RS01970	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KDJ95_RS01975	COG0110	maltose O-acetyltransferase activity
KDJ95_RS02000	COG0101	tRNA pseudouridine synthase activity
KDJ95_RS02005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KDJ95_RS02020	COG4968	Prepilin-type N-terminal cleavage methylation domain
KDJ95_RS02035	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KDJ95_RS02040	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KDJ95_RS02060	COG1136	(ABC) transporter
KDJ95_RS02065	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KDJ95_RS02075	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KDJ95_RS02105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KDJ95_RS02110	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KDJ95_RS02120	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KDJ95_RS02125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KDJ95_RS02135	COG2814	Major facilitator Superfamily
KDJ95_RS02145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KDJ95_RS02150	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KDJ95_RS02150	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KDJ95_RS02155	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KDJ95_RS02160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KDJ95_RS02165	COG0552	protein localization to endoplasmic reticulum
KDJ95_RS02170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KDJ95_RS02190	COG1546	Belongs to the CinA family
KDJ95_RS02190	COG1058	Belongs to the CinA family
KDJ95_RS02200	COG0456	acetyltransferase
KDJ95_RS02225	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KDJ95_RS02230	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KDJ95_RS02235	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KDJ95_RS02240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KDJ95_RS02255	COG0758	DNA mediated transformation
KDJ95_RS02260	COG1686	Belongs to the peptidase S11 family
KDJ95_RS02265	COG0012	GTP binding
KDJ95_RS02270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KDJ95_RS02280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KDJ95_RS02280	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KDJ95_RS02295	COG3119	arylsulfatase activity
KDJ95_RS02320	COG2259	Doxx family
KDJ95_RS02325	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KDJ95_RS02355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KDJ95_RS02375	COG2326	polyphosphate kinase activity
KDJ95_RS02380	COG1349	DNA-binding transcription factor activity
KDJ95_RS02395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KDJ95_RS02400	COG1162	GTPase activity
KDJ95_RS02415	COG0742	ribosomal rna small subunit methyltransferase
KDJ95_RS02430	COG2326	polyphosphate kinase activity
KDJ95_RS02440	COG5434	Belongs to the glycosyl hydrolase 28 family
KDJ95_RS02450	COG1073	alpha beta
KDJ95_RS02455	COG0802	atpase or kinase
KDJ95_RS02460	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KDJ95_RS02465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KDJ95_RS02470	COG0735	belongs to the Fur family
KDJ95_RS02475	COG0396	ATPase activity
KDJ95_RS02480	COG0719	Fe-S assembly protein
KDJ95_RS02485	COG0719	Fe-S assembly protein
KDJ95_RS02500	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KDJ95_RS02545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KDJ95_RS02565	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KDJ95_RS02570	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KDJ95_RS02575	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KDJ95_RS02580	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KDJ95_RS02585	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KDJ95_RS02590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KDJ95_RS02600	COG0356	it plays a direct role in the translocation of protons across the membrane
KDJ95_RS02650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KDJ95_RS02675	COG1045	serine acetyltransferase
KDJ95_RS02680	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KDJ95_RS02685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KDJ95_RS02690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KDJ95_RS02700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KDJ95_RS02710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KDJ95_RS02715	COG0047	phosphoribosylformylglycinamidine synthase activity
KDJ95_RS02725	COG1363	Peptidase, m42
KDJ95_RS02740	COG1077	Cell shape determining protein MreB Mrl
KDJ95_RS02745	COG1530	ribonuclease E activity
KDJ95_RS02770	COG0848	biopolymer transport protein
KDJ95_RS02785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KDJ95_RS02800	COG0134	indole-3-glycerol-phosphate synthase activity
KDJ95_RS02805	COG0792	nuclease activity
KDJ95_RS02815	COG1253	flavin adenine dinucleotide binding
KDJ95_RS02825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KDJ95_RS02830	COG0137	argininosuccinate synthase activity
KDJ95_RS02850	COG0149	triose-phosphate isomerase activity
KDJ95_RS02885	COG1040	competence protein
KDJ95_RS02895	COG3956	TIGRFAM MazG family protein
KDJ95_RS02915	COG1663	tetraacyldisaccharide 4'-kinase activity
KDJ95_RS02920	COG0612	Peptidase, M16
KDJ95_RS02945	COG0673	inositol 2-dehydrogenase activity
KDJ95_RS02950	COG3034	peptidoglycan biosynthetic process
KDJ95_RS02970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KDJ95_RS02975	COG0424	maF-like protein
KDJ95_RS02980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KDJ95_RS03010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KDJ95_RS03020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KDJ95_RS03030	COG0571	ribonuclease III activity
KDJ95_RS03040	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KDJ95_RS03080	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KDJ95_RS03095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KDJ95_RS03115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KDJ95_RS03120	COG0631	protein serine/threonine phosphatase activity
KDJ95_RS03130	COG2226	methyltransferase
KDJ95_RS03140	COG2076	Multidrug Resistance protein
KDJ95_RS03180	COG2255	four-way junction helicase activity
KDJ95_RS03185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KDJ95_RS03190	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KDJ95_RS03195	COG1215	transferase activity, transferring glycosyl groups
KDJ95_RS03200	COG1216	Glycosyl transferase, family 2
KDJ95_RS03200	COG0463	Glycosyl transferase, family 2
KDJ95_RS03225	COG0438	transferase activity, transferring glycosyl groups
KDJ95_RS03235	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KDJ95_RS03245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KDJ95_RS03255	COG0482	sulfurtransferase activity
KDJ95_RS03260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KDJ95_RS03270	COG2860	membrane
KDJ95_RS03275	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KDJ95_RS03280	COG2001	Belongs to the MraZ family
KDJ95_RS03285	COG0275	rRNA processing
KDJ95_RS03295	COG0768	penicillin binding
KDJ95_RS03300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KDJ95_RS03305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KDJ95_RS03310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KDJ95_RS03315	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KDJ95_RS03325	COG0772	Belongs to the SEDS family
KDJ95_RS03330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KDJ95_RS03335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KDJ95_RS03340	COG1181	Belongs to the D-alanine--D-alanine ligase family
KDJ95_RS03350	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KDJ95_RS03355	COG0860	N-Acetylmuramoyl-L-alanine amidase
KDJ95_RS03360	COG0321	lipoyl(octanoyl) transferase activity
KDJ95_RS03365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KDJ95_RS03370	COG0066	3-isopropylmalate dehydratase activity
KDJ95_RS03380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KDJ95_RS03390	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KDJ95_RS03395	COG4608	Belongs to the ABC transporter superfamily
KDJ95_RS03400	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KDJ95_RS03405	COG0052	Belongs to the universal ribosomal protein uS2 family
KDJ95_RS03415	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KDJ95_RS03430	COG1137	ATPase activity
KDJ95_RS03440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KDJ95_RS03455	COG1733	regulation of RNA biosynthetic process
KDJ95_RS03480	COG0017	Asparaginyl-tRNA synthetase
KDJ95_RS03490	COG3118	belongs to the thioredoxin family
KDJ95_RS03540	COG0583	DNA-binding transcription factor activity
KDJ95_RS03545	COG2855	membrane
KDJ95_RS03550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KDJ95_RS03560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KDJ95_RS03570	COG0602	queuosine metabolic process
KDJ95_RS03575	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KDJ95_RS03580	COG0217	transcriptional regulatory protein
KDJ95_RS03585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KDJ95_RS03590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KDJ95_RS03590	COG4651	solute:proton antiporter activity
KDJ95_RS03600	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KDJ95_RS03605	COG4864	UPF0365 protein
KDJ95_RS03615	COG2022	thiamine diphosphate biosynthetic process
KDJ95_RS03620	COG0531	amino acid
KDJ95_RS03630	COG0628	permease
KDJ95_RS03635	COG0019	diaminopimelate decarboxylase activity
KDJ95_RS03640	COG0191	fructose-bisphosphate aldolase activity
KDJ95_RS03645	COG1217	gtp-binding protein TYPA
KDJ95_RS03675	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KDJ95_RS03715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KDJ95_RS03720	COG0517	IMP dehydrogenase activity
KDJ95_RS03720	COG0516	GMP reductase activity
KDJ95_RS03725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KDJ95_RS03725	COG0519	Catalyzes the synthesis of GMP from XMP
KDJ95_RS03735	COG0546	phosphoglycolate phosphatase activity
KDJ95_RS03755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KDJ95_RS03770	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KDJ95_RS03775	COG0196	riboflavin kinase activity
KDJ95_RS03780	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KDJ95_RS03795	COG1408	metallophosphoesterase
KDJ95_RS03805	COG1216	Glycosyl transferase, family 2
KDJ95_RS03805	COG1442	glycosyl transferase family 8
KDJ95_RS03815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KDJ95_RS03820	COG1216	Glycosyl transferase, family 2
KDJ95_RS03840	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KDJ95_RS03840	COG2755	lipolytic protein G-D-S-L family
KDJ95_RS03855	COG0471	metal ion transport
KDJ95_RS03855	COG0490	domain, Protein
KDJ95_RS03895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KDJ95_RS03905	COG0477	Major facilitator Superfamily
KDJ95_RS03910	COG1607	acyl-coa hydrolase
KDJ95_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
KDJ95_RS03930	COG1525	nuclease
KDJ95_RS03945	COG1475	DNA binding
KDJ95_RS03950	COG3969	phosphoadenosine phosphosulfate
KDJ95_RS03965	COG0473	3-isopropylmalate dehydrogenase activity
KDJ95_RS03990	COG2873	o-acetylhomoserine
KDJ95_RS03995	COG0535	radical SAM domain protein
KDJ95_RS04000	COG0535	radical SAM domain protein
KDJ95_RS04015	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KDJ95_RS04020	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KDJ95_RS04030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KDJ95_RS04035	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KDJ95_RS04035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KDJ95_RS04035	COG1013	pyruvate-flavodoxin oxidoreductase activity
KDJ95_RS04035	COG0674	pyruvate-flavodoxin oxidoreductase activity
KDJ95_RS04045	COG1733	regulation of RNA biosynthetic process
KDJ95_RS04055	COG0107	imidazoleglycerol-phosphate synthase activity
KDJ95_RS04065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KDJ95_RS04075	COG1643	Atp-dependent helicase
KDJ95_RS04080	COG0440	acetolactate synthase activity
KDJ95_RS04085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KDJ95_RS04095	COG0445	tRNA wobble uridine modification
KDJ95_RS04100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KDJ95_RS04100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KDJ95_RS04105	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KDJ95_RS04115	COG0592	DNA-directed DNA polymerase activity
KDJ95_RS04140	COG0791	NLP P60 protein
KDJ95_RS04140	COG1388	LysM domain
KDJ95_RS04145	COG0084	hydrolase, TatD family'
KDJ95_RS04155	COG3250	beta-galactosidase activity
KDJ95_RS04170	COG2205	protein histidine kinase activity
KDJ95_RS04175	COG0745	RESPONSE REGULATOR receiver
KDJ95_RS04185	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KDJ95_RS04210	COG0542	response to heat
KDJ95_RS04255	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KDJ95_RS04265	COG0659	secondary active sulfate transmembrane transporter activity
KDJ95_RS04270	COG0165	Argininosuccinate lyase
KDJ95_RS04285	COG0148	phosphopyruvate hydratase activity
KDJ95_RS04290	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KDJ95_RS04300	COG3481	metal-dependent phosphohydrolase, HD sub domain
KDJ95_RS04310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KDJ95_RS04315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KDJ95_RS04345	COG0490	domain, Protein
KDJ95_RS04345	COG2985	domain, Protein
KDJ95_RS04360	COG0471	metal ion transport
KDJ95_RS04385	COG2194	sulfuric ester hydrolase activity
KDJ95_RS04390	COG1592	Rubrerythrin
KDJ95_RS04400	COG1363	Peptidase, m42
KDJ95_RS04405	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KDJ95_RS04415	COG1785	Belongs to the alkaline phosphatase family
KDJ95_RS04420	COG1970	mechanosensitive ion channel activity
KDJ95_RS04425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KDJ95_RS04435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KDJ95_RS04445	COG2217	Heavy metal translocating P-type atpase
KDJ95_RS04450	COG0497	DNA recombination
KDJ95_RS04455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KDJ95_RS04455	COG0321	lipoyl(octanoyl) transferase activity
KDJ95_RS04460	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KDJ95_RS04490	COG0508	dehydrogenase complex catalyzes the overall conversion of
KDJ95_RS04495	COG0022	dehydrogenase e1 component
KDJ95_RS04500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KDJ95_RS04505	COG0789	Transcriptional regulator
KDJ95_RS04510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KDJ95_RS04515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KDJ95_RS04580	COG3409	Peptidoglycan-binding domain 1 protein
KDJ95_RS04580	COG5632	N-Acetylmuramoyl-L-alanine amidase
KDJ95_RS04585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KDJ95_RS04610	COG1690	Belongs to the RtcB family
KDJ95_RS04620	COG2814	Major facilitator Superfamily
KDJ95_RS04630	COG2096	Adenosyltransferase
KDJ95_RS04640	COG0557	exoribonuclease II activity
KDJ95_RS04655	COG0826	peptidase U32
KDJ95_RS04660	COG0285	dihydrofolate synthase activity
KDJ95_RS04675	COG0673	inositol 2-dehydrogenase activity
KDJ95_RS04680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KDJ95_RS04685	COG0737	Belongs to the 5'-nucleotidase family
KDJ95_RS04695	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KDJ95_RS04700	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KDJ95_RS04715	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KDJ95_RS04720	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KDJ95_RS04725	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KDJ95_RS04730	COG0200	Binds to the 23S rRNA
KDJ95_RS04735	COG0201	protein transport
KDJ95_RS04740	COG0563	adenylate kinase activity
KDJ95_RS04745	COG0024	Methionine aminopeptidase
KDJ95_RS04760	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KDJ95_RS04765	COG1442	glycosyl transferase family 8
KDJ95_RS04775	COG1216	Glycosyl transferase, family 2
KDJ95_RS04785	COG1216	Glycosyl transferase, family 2
KDJ95_RS04795	COG1216	Glycosyl transferase, family 2
KDJ95_RS04800	COG0693	protein deglycase activity
KDJ95_RS04805	COG0508	dehydrogenase complex catalyzes the overall conversion of
KDJ95_RS04810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KDJ95_RS04815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KDJ95_RS04825	COG1966	Carbon starvation protein
KDJ95_RS04835	COG3119	arylsulfatase activity
KDJ95_RS04840	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KDJ95_RS04845	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KDJ95_RS04850	COG0195	Participates in both transcription termination and antitermination
KDJ95_RS04855	COG0708	Exodeoxyribonuclease III
KDJ95_RS04860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KDJ95_RS04865	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KDJ95_RS04870	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
KDJ95_RS04880	COG1716	ATPase activity
KDJ95_RS04880	COG1131	(ABC) transporter
KDJ95_RS04880	COG0842	Transport permease protein
KDJ95_RS04900	COG0724	RNA recognition motif
KDJ95_RS04905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KDJ95_RS04925	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KDJ95_RS04935	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KDJ95_RS04940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KDJ95_RS04955	COG1490	D-aminoacyl-tRNA deacylase activity
KDJ95_RS04980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KDJ95_RS04985	COG1053	succinate dehydrogenase
KDJ95_RS05030	COG1028	Short-chain dehydrogenase reductase Sdr
KDJ95_RS05040	COG0488	(ABC) transporter
KDJ95_RS05050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KDJ95_RS05060	COG1253	flavin adenine dinucleotide binding
KDJ95_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
KDJ95_RS05075	COG1073	alpha beta
KDJ95_RS05140	COG2267	carboxylic ester hydrolase activity
KDJ95_RS05145	COG2095	MarC family integral membrane protein
KDJ95_RS05185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KDJ95_RS05190	COG0488	(ABC) transporter
KDJ95_RS05200	COG0697	spore germination
KDJ95_RS05210	COG0215	cysteine-tRNA ligase activity
KDJ95_RS05220	COG3119	arylsulfatase activity
KDJ95_RS05235	COG0481	GTPase activity
KDJ95_RS05250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KDJ95_RS05255	COG0085	RNA polymerase activity
KDJ95_RS05260	COG0222	ribosome binding
KDJ95_RS05265	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KDJ95_RS05270	COG0081	regulation of translation
KDJ95_RS05275	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KDJ95_RS05280	COG0250	Participates in transcription elongation, termination and antitermination
KDJ95_RS05295	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KDJ95_RS05305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KDJ95_RS05315	COG0740	serine-type endopeptidase activity
KDJ95_RS05320	COG0544	peptidyl-prolyl cis-trans isomerase activity
KDJ95_RS05335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KDJ95_RS05355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KDJ95_RS05395	COG2226	methyltransferase
KDJ95_RS05400	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KDJ95_RS05405	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KDJ95_RS05420	COG0446	pyridine nucleotide-disulphide oxidoreductase
KDJ95_RS05420	COG1902	pentaerythritol trinitrate reductase activity
KDJ95_RS05430	COG3119	arylsulfatase activity
KDJ95_RS05435	COG0514	ATP-dependent DNA helicase (RecQ)
KDJ95_RS05455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KDJ95_RS05460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KDJ95_RS05500	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KDJ95_RS05515	COG1858	cytochrome C peroxidase
KDJ95_RS05520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KDJ95_RS05525	COG0590	tRNA wobble adenosine to inosine editing
KDJ95_RS05530	COG1940	carbohydrate kinase activity
KDJ95_RS05535	COG2217	Heavy metal translocating P-type atpase
KDJ95_RS05540	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KDJ95_RS05545	COG0237	dephospho-CoA kinase activity
KDJ95_RS05575	COG1363	Peptidase, m42
KDJ95_RS05580	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KDJ95_RS05590	COG0006	proline dipeptidase activity
KDJ95_RS05595	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KDJ95_RS05605	COG0745	RESPONSE REGULATOR receiver
KDJ95_RS05610	COG0129	dihydroxy-acid dehydratase activity
KDJ95_RS05635	COG1368	sulfuric ester hydrolase activity
KDJ95_RS05670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KDJ95_RS05675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KDJ95_RS05695	COG0534	Mate efflux family protein
KDJ95_RS05700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KDJ95_RS05715	COG1876	peptidase activity
KDJ95_RS05760	COG3209	COG3209 Rhs family protein
KDJ95_RS05810	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KDJ95_RS05815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KDJ95_RS05820	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KDJ95_RS05825	COG2205	protein histidine kinase activity
KDJ95_RS05830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KDJ95_RS05840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KDJ95_RS05855	COG0667	Aldo Keto reductase
KDJ95_RS05860	COG0789	Transcriptional regulator
KDJ95_RS05905	COG0714	Associated with various cellular activities
KDJ95_RS05910	COG2311	Membrane
KDJ95_RS05930	COG1090	epimerase
KDJ95_RS05940	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KDJ95_RS05945	COG1119	ATPase activity
KDJ95_RS05950	COG2186	Transcriptional regulator
KDJ95_RS05970	COG0148	phosphopyruvate hydratase activity
KDJ95_RS05975	COG0436	Aminotransferase
KDJ95_RS05980	COG1477	protein flavinylation
KDJ95_RS05995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KDJ95_RS06005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KDJ95_RS06025	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KDJ95_RS06035	COG1199	ATP-dependent helicase activity
KDJ95_RS06040	COG1122	ATPase activity
KDJ95_RS06065	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KDJ95_RS06070	COG0598	Magnesium transport protein CorA
KDJ95_RS06075	COG0359	binds to the 23S rRNA
KDJ95_RS06080	COG0138	bifunctional purine biosynthesis protein purh
KDJ95_RS06085	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KDJ95_RS06090	COG0736	holo-[acyl-carrier-protein] synthase activity
KDJ95_RS06100	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
KDJ95_RS06105	COG5632	N-Acetylmuramoyl-L-alanine amidase
KDJ95_RS06105	COG3409	Peptidoglycan-binding domain 1 protein
KDJ95_RS06110	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KDJ95_RS06120	COG0437	4 iron, 4 sulfur cluster binding
KDJ95_RS06140	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KDJ95_RS06195	COG0284	orotidine-5'-phosphate decarboxylase activity
KDJ95_RS06215	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KDJ95_RS06220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KDJ95_RS06240	COG2003	Belongs to the UPF0758 family
KDJ95_RS06245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KDJ95_RS06245	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KDJ95_RS06250	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KDJ95_RS06255	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KDJ95_RS06260	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KDJ95_RS06265	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KDJ95_RS06270	COG0322	excinuclease ABC activity
KDJ95_RS06275	COG0811	peptide transport
KDJ95_RS06280	COG0848	biopolymer transport protein
KDJ95_RS06290	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KDJ95_RS06295	COG0483	inositol monophosphate 1-phosphatase activity
KDJ95_RS06300	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KDJ95_RS06310	COG1482	cell wall glycoprotein biosynthetic process
KDJ95_RS06320	COG1757	Na H antiporter
KDJ95_RS06325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KDJ95_RS06330	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KDJ95_RS06335	COG0505	Belongs to the CarA family
KDJ95_RS06340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KDJ95_RS06355	COG0067	glutamate synthase
KDJ95_RS06355	COG0069	glutamate synthase activity
KDJ95_RS06355	COG0070	glutamate synthase
KDJ95_RS06365	COG0706	membrane insertase activity
KDJ95_RS06370	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KDJ95_RS06380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KDJ95_RS06390	COG0657	acetylesterase activity
KDJ95_RS06390	COG2755	lipolytic protein G-D-S-L family
KDJ95_RS06400	COG0676	glucose-6-phosphate 1-epimerase activity
KDJ95_RS06405	COG0259	pyridoxamine-phosphate oxidase activity
KDJ95_RS06420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KDJ95_RS06435	COG1760	l-serine dehydratase
KDJ95_RS06440	COG0492	ferredoxin-NADP+ reductase activity
KDJ95_RS06440	COG3118	belongs to the thioredoxin family
KDJ95_RS06490	COG1408	metallophosphoesterase
KDJ95_RS06500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KDJ95_RS06505	COG0545	Peptidyl-prolyl cis-trans isomerase
KDJ95_RS06520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KDJ95_RS06530	COG0826	peptidase U32
KDJ95_RS06535	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KDJ95_RS06555	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KDJ95_RS06565	COG1116	anion transmembrane transporter activity
KDJ95_RS06575	COG0529	Catalyzes the synthesis of activated sulfate
KDJ95_RS06575	COG2895	sulfate adenylyltransferase (ATP) activity
KDJ95_RS06580	COG0175	sulfate reduction
KDJ95_RS06585	COG0175	sulfate reduction
KDJ95_RS06605	COG0581	inorganic phosphate transmembrane transporter activity
KDJ95_RS06610	COG0573	inorganic phosphate transmembrane transporter activity
KDJ95_RS06620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KDJ95_RS06630	COG2017	converts alpha-aldose to the beta-anomer
KDJ95_RS06645	COG0612	Peptidase, M16
KDJ95_RS06675	COG0233	cytoplasmic translational termination
KDJ95_RS06680	COG0528	UMP kinase activity
KDJ95_RS06685	COG0668	transmembrane transport
KDJ95_RS06690	COG0450	alkyl hydroperoxide reductase
KDJ95_RS06695	COG0733	neurotransmitter:sodium symporter activity
KDJ95_RS06710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KDJ95_RS06720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KDJ95_RS06725	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KDJ95_RS06730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KDJ95_RS06960	COG0305	Participates in initiation and elongation during chromosome replication
KDJ95_RS06975	COG0842	Transport permease protein
KDJ95_RS06980	COG0842	Transport permease protein
KDJ95_RS06985	COG1131	(ABC) transporter
KDJ95_RS06995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KDJ95_RS07000	COG1183	phosphatidylcholine synthase activity
KDJ95_RS07010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KDJ95_RS07020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KDJ95_RS07025	COG1028	Short-chain dehydrogenase reductase Sdr
KDJ95_RS07045	COG0156	8-amino-7-oxononanoate synthase activity
KDJ95_RS07065	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KDJ95_RS07070	COG0124	histidyl-tRNA synthetase
KDJ95_RS07075	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KDJ95_RS07080	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KDJ95_RS07085	COG0298	carbon dioxide binding
KDJ95_RS07110	COG0438	transferase activity, transferring glycosyl groups
KDJ95_RS07115	COG0443	Heat shock 70 kDa protein
KDJ95_RS07120	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KDJ95_RS07125	COG0459	protein refolding
KDJ95_RS07175	COG0632	four-way junction helicase activity
KDJ95_RS07185	COG0126	phosphoglycerate kinase activity
KDJ95_RS07195	COG1082	Xylose isomerase domain protein TIM barrel
KDJ95_RS07200	COG2815	serine threonine protein kinase
KDJ95_RS07200	COG0515	serine threonine protein kinase
KDJ95_RS07205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KDJ95_RS07215	COG2271	Major facilitator Superfamily
KDJ95_RS07230	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KDJ95_RS07240	COG0037	tRNA processing
KDJ95_RS07245	COG0254	rRNA binding
KDJ95_RS07280	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KDJ95_RS07285	COG0039	L-malate dehydrogenase activity
KDJ95_RS07305	COG0778	Nitroreductase
KDJ95_RS07310	COG0564	pseudouridine synthase activity
KDJ95_RS07330	COG1126	abc transporter atp-binding protein
KDJ95_RS07335	COG0765	amino acid transport
KDJ95_RS07345	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KDJ95_RS07350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KDJ95_RS07370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KDJ95_RS07395	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KDJ95_RS07400	COG1872	DUF167
KDJ95_RS07405	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KDJ95_RS07410	COG0484	heat shock protein binding
KDJ95_RS07415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KDJ95_RS07425	COG5434	Belongs to the glycosyl hydrolase 28 family
KDJ95_RS07440	COG0277	FAD linked oxidase domain protein
KDJ95_RS07465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KDJ95_RS07470	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KDJ95_RS07480	COG0131	Imidazoleglycerol-phosphate dehydratase
KDJ95_RS07485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KDJ95_RS07490	COG0360	Binds together with S18 to 16S ribosomal RNA
KDJ95_RS07495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KDJ95_RS07510	COG1686	Belongs to the peptidase S11 family
KDJ95_RS07515	COG0205	6-phosphofructokinase activity
KDJ95_RS07525	COG0428	transporter
KDJ95_RS07530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KDJ95_RS07545	COG3977	Valine--pyruvate aminotransferase
KDJ95_RS07550	COG1561	YicC-like family, N-terminal region
KDJ95_RS07560	COG0471	metal ion transport
KDJ95_RS07560	COG3273	potassium ion transport
KDJ95_RS07565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KDJ95_RS07580	COG1575	Belongs to the MenA family. Type 1 subfamily
KDJ95_RS07615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KDJ95_RS07615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KDJ95_RS07635	COG0202	RNA polymerase activity
KDJ95_RS07640	COG0203	ribosomal protein L17
KDJ95_RS07645	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KDJ95_RS07650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KDJ95_RS07665	COG2885	chlorophyll binding
KDJ95_RS07700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KDJ95_RS07740	COG0667	Aldo Keto reductase
KDJ95_RS07745	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KDJ95_RS07760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KDJ95_RS07765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KDJ95_RS07770	COG0134	indole-3-glycerol-phosphate synthase activity
KDJ95_RS07775	COG0135	phosphoribosylanthranilate isomerase activity
KDJ95_RS07785	COG0159	tryptophan synthase activity
KDJ95_RS07800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KDJ95_RS07805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KDJ95_RS07815	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KDJ95_RS07845	COG0561	phosphatase activity
KDJ95_RS07850	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KDJ95_RS07855	COG2223	nitrite transmembrane transporter activity
KDJ95_RS07870	COG0556	nucleotide-excision repair
KDJ95_RS07875	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KDJ95_RS07880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KDJ95_RS07885	COG0750	zinc metalloprotease
KDJ95_RS07900	COG1074	ATP-dependent DNA helicase activity
KDJ95_RS07910	COG0697	spore germination
KDJ95_RS07920	COG2373	Large extracellular alpha-helical protein
KDJ95_RS07925	COG1979	alcohol dehydrogenase
KDJ95_RS07935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KDJ95_RS07960	COG0372	Belongs to the citrate synthase family
KDJ95_RS07975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KDJ95_RS07985	COG1187	pseudouridine synthase activity
KDJ95_RS07995	COG0105	UTP biosynthetic process
KDJ95_RS08000	COG1215	transferase activity, transferring glycosyl groups
KDJ95_RS08005	COG0463	Glycosyl transferase, family 2
KDJ95_RS08015	COG1459	type II secretion system
KDJ95_RS08020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KDJ95_RS08025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KDJ95_RS08030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KDJ95_RS08045	COG0728	peptidoglycan biosynthetic process
KDJ95_RS08050	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KDJ95_RS08050	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KDJ95_RS08060	COG1649	PFAM Uncharacterised BCR, COG1649
KDJ95_RS08065	COG1691	(AIR) carboxylase
KDJ95_RS08070	COG0037	tRNA processing
KDJ95_RS08075	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KDJ95_RS08080	COG0142	geranyltranstransferase activity
KDJ95_RS08095	COG2151	metal-sulfur cluster biosynthetic enzyme
KDJ95_RS08115	COG1007	ATP synthesis coupled electron transport
KDJ95_RS08120	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KDJ95_RS08130	COG0713	ATP synthesis coupled electron transport
KDJ95_RS08135	COG0839	Belongs to the complex I subunit 6 family
KDJ95_RS08145	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KDJ95_RS08150	COG1034	ATP synthesis coupled electron transport
KDJ95_RS08155	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KDJ95_RS08160	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KDJ95_RS08165	COG0649	NAD binding
KDJ95_RS08175	COG0726	polysaccharide deacetylase
KDJ95_RS08185	COG0307	riboflavin synthase, alpha
KDJ95_RS08190	COG2264	protein methyltransferase activity
KDJ95_RS08195	COG3210	domain, Protein
KDJ95_RS08200	COG1640	4-alpha-glucanotransferase
KDJ95_RS08210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KDJ95_RS08215	COG1030	water channel activity
KDJ95_RS08220	COG0358	DNA primase activity
KDJ95_RS08225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KDJ95_RS08230	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KDJ95_RS08245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KDJ95_RS08250	COG0793	Belongs to the peptidase S41A family
KDJ95_RS08265	COG1643	Atp-dependent helicase
KDJ95_RS08290	COG1450	Type ii and iii secretion system protein
KDJ95_RS08305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KDJ95_RS08325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KDJ95_RS08330	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KDJ95_RS08340	COG0268	Binds directly to 16S ribosomal RNA
KDJ95_RS08345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KDJ95_RS08350	COG0028	Belongs to the TPP enzyme family
KDJ95_RS08360	COG0688	phosphatidylethanolamine metabolic process
KDJ95_RS08365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KDJ95_RS08370	COG0495	leucyl-tRNA aminoacylation
KDJ95_RS08375	COG3119	arylsulfatase activity
KDJ95_RS08390	COG1166	arginine decarboxylase activity
KDJ95_RS08430	COG3250	beta-galactosidase activity
KDJ95_RS08435	COG3250	beta-galactosidase activity
KDJ95_RS08440	COG3250	beta-galactosidase activity
KDJ95_RS08445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KDJ95_RS08450	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KDJ95_RS08460	COG0205	6-phosphofructokinase activity
KDJ95_RS08510	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KDJ95_RS08515	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KDJ95_RS08520	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KDJ95_RS08530	COG4771	TonB-dependent receptor
KDJ95_RS08550	COG0402	S-adenosylhomocysteine deaminase activity
KDJ95_RS08555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KDJ95_RS08580	COG1294	oxidase, subunit
KDJ95_RS08585	COG1271	oxidase subunit
KDJ95_RS08595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KDJ95_RS08615	COG1846	Transcriptional regulator
KDJ95_RS08640	COG2949	membrane
KDJ95_RS08665	COG0514	ATP-dependent DNA helicase (RecQ)
KDJ95_RS08680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KDJ95_RS08685	COG0045	succinate-CoA ligase (ADP-forming) activity
KDJ95_RS08690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KDJ95_RS08745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KDJ95_RS08750	COG2205	protein histidine kinase activity
KDJ95_RS08765	COG0113	porphobilinogen synthase activity
KDJ95_RS08775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KDJ95_RS08795	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KDJ95_RS08835	COG3475	LICD family
KDJ95_RS08840	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KDJ95_RS08850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KDJ95_RS08855	COG3475	LICD family
KDJ95_RS08860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KDJ95_RS08870	COG2166	iron-sulfur cluster assembly
KDJ95_RS08875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KDJ95_RS08885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KDJ95_RS08890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KDJ95_RS08895	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KDJ95_RS08900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KDJ95_RS08905	COG1131	(ABC) transporter
KDJ95_RS08920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KDJ95_RS08935	COG1215	transferase activity, transferring glycosyl groups
KDJ95_RS08945	COG2967	ApaG domain
KDJ95_RS08955	COG1522	sequence-specific DNA binding
KDJ95_RS08960	COG0436	Aminotransferase
KDJ95_RS08975	COG0423	glycine-tRNA ligase activity
KDJ95_RS08980	COG0656	L-ascorbic acid biosynthetic process
KDJ95_RS08995	COG2304	oxidoreductase activity
KDJ95_RS09010	COG0714	Associated with various cellular activities
KDJ95_RS09015	COG0154	amidase activity
KDJ95_RS09020	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KDJ95_RS09060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KDJ95_RS09070	COG2755	lipolytic protein G-D-S-L family
KDJ95_RS09070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KDJ95_RS09090	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KDJ95_RS09100	COG0656	L-ascorbic acid biosynthetic process
KDJ95_RS09110	COG0667	Aldo Keto reductase
KDJ95_RS09115	COG1408	metallophosphoesterase
KDJ95_RS09135	COG0667	Aldo Keto reductase
KDJ95_RS09145	COG2249	NAD(P)H dehydrogenase (quinone) activity
KDJ95_RS09150	COG0789	Transcriptional regulator
KDJ95_RS09165	COG0534	Mate efflux family protein
KDJ95_RS09185	COG1091	dTDP-4-dehydrorhamnose reductase activity
KDJ95_RS09200	COG1837	Belongs to the UPF0109 family
KDJ95_RS09205	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KDJ95_RS09210	COG0363	glucosamine-6-phosphate deaminase activity
KDJ95_RS09230	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KDJ95_RS09240	COG1741	Belongs to the pirin family
KDJ95_RS09255	COG1070	Carbohydrate kinase
KDJ95_RS09270	COG0738	Major facilitator superfamily
KDJ95_RS09285	COG1595	DNA-templated transcription, initiation
KDJ95_RS09300	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KDJ95_RS09320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KDJ95_RS09335	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KDJ95_RS09345	COG2132	Multicopper oxidase
KDJ95_RS09350	COG0697	spore germination
KDJ95_RS09360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KDJ95_RS09365	COG4608	Belongs to the ABC transporter superfamily
KDJ95_RS09370	COG0444	Belongs to the ABC transporter superfamily
KDJ95_RS09375	COG4166	transmembrane transport
KDJ95_RS09380	COG4239	(ABC) transporter, permease
KDJ95_RS09385	COG0601	transmembrane transport
KDJ95_RS09405	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KDJ95_RS09410	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KDJ95_RS09415	COG3738	Protein conserved in bacteria
KDJ95_RS09420	COG0151	Belongs to the GarS family
KDJ95_RS09435	COG0811	peptide transport
KDJ95_RS09445	COG0242	peptide deformylase activity
KDJ95_RS09480	COG2010	Cytochrome c
KDJ95_RS09490	COG3258	Cytochrome c
KDJ95_RS09500	COG3274	enterobacterial common antigen metabolic process
KDJ95_RS09505	COG0538	isocitrate dehydrogenase activity
KDJ95_RS09520	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KDJ95_RS09525	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KDJ95_RS09530	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KDJ95_RS09540	COG0668	transmembrane transport
KDJ95_RS09545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KDJ95_RS09545	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
KDJ95_RS09550	COG0805	protein transport
KDJ95_RS09555	COG1968	undecaprenyl-diphosphatase activity
KDJ95_RS09575	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KDJ95_RS09585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KDJ95_RS09595	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KDJ95_RS09605	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KDJ95_RS09615	COG1408	metallophosphoesterase
KDJ95_RS09640	COG4974	Belongs to the 'phage' integrase family
KDJ95_RS09665	COG1454	alcohol dehydrogenase
KDJ95_RS09670	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KDJ95_RS09685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KDJ95_RS09695	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KDJ95_RS09695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KDJ95_RS09700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KDJ95_RS09740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KDJ95_RS09750	COG4607	ABC-type enterochelin transport system periplasmic component
KDJ95_RS09755	COG4604	ABC transporter, ATP-binding protein
KDJ95_RS09760	COG4605	iron ion homeostasis
KDJ95_RS09765	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KDJ95_RS09800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KDJ95_RS09800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KDJ95_RS09815	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KDJ95_RS09820	COG2195	Cleaves the N-terminal amino acid of tripeptides
KDJ95_RS09840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KDJ95_RS09855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KDJ95_RS09880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KDJ95_RS09880	COG0519	Catalyzes the synthesis of GMP from XMP
KDJ95_RS09885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KDJ95_RS09915	COG1410	methionine synthase
KDJ95_RS09915	COG0646	methionine synthase
KDJ95_RS09920	COG2966	Psort location CytoplasmicMembrane, score
KDJ95_RS09925	COG3610	response to peptide
KDJ95_RS09935	COG0460	homoserine dehydrogenase
KDJ95_RS09940	COG0527	aspartate kinase activity
KDJ95_RS09950	COG5522	Integral membrane protein (intg_mem_TP0381)
KDJ95_RS09960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KDJ95_RS09965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KDJ95_RS09970	COG1194	a g-specific adenine glycosylase
KDJ95_RS09975	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KDJ95_RS09980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KDJ95_RS09980	COG0574	Belongs to the PEP-utilizing enzyme family
KDJ95_RS09985	COG0166	Belongs to the GPI family
KDJ95_RS09995	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KDJ95_RS10005	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KDJ95_RS10005	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KDJ95_RS10015	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KDJ95_RS10015	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KDJ95_RS10050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KDJ95_RS10055	COG2818	Glycosylase
KDJ95_RS10075	COG3033	Beta-eliminating lyase
KDJ95_RS10090	COG0072	phenylalanine-tRNA ligase activity
KDJ95_RS10090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KDJ95_RS10110	COG0326	Molecular chaperone. Has ATPase activity
KDJ95_RS10115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KDJ95_RS10135	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KDJ95_RS10150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KDJ95_RS10155	COG1959	2 iron, 2 sulfur cluster binding
KDJ95_RS10170	COG0352	thiamine-phosphate diphosphorylase activity
KDJ95_RS10175	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KDJ95_RS10200	COG1703	isobutyryl-CoA mutase activity
KDJ95_RS10220	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KDJ95_RS10230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KDJ95_RS10235	COG0418	dihydroorotase activity
KDJ95_RS10250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KDJ95_RS10270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KDJ95_RS10285	COG0534	Mate efflux family protein
KDJ95_RS10290	COG0489	protein tyrosine kinase activity
KDJ95_RS10300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KDJ95_RS10305	COG0339	signal peptide processing
KDJ95_RS10310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KDJ95_RS10320	COG1538	Outer membrane efflux protein
KDJ95_RS10335	COG4112	unkown
KDJ95_RS10350	COG0038	chloride channel
KDJ95_RS10360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KDJ95_RS10365	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KDJ95_RS10370	COG0586	Pfam SNARE associated Golgi protein
KDJ95_RS10440	COG1012	belongs to the aldehyde dehydrogenase family
KDJ95_RS10455	COG0753	catalase activity
KDJ95_RS10465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KDJ95_RS10470	COG1592	Rubrerythrin
KDJ95_RS10475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KDJ95_RS10485	COG1674	ftsk spoiiie
KDJ95_RS10495	COG0489	protein tyrosine kinase activity
KDJ95_RS10505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KDJ95_RS10515	COG0438	transferase activity, transferring glycosyl groups
KDJ95_RS10525	COG0438	transferase activity, transferring glycosyl groups
KDJ95_RS10565	COG0110	maltose O-acetyltransferase activity
KDJ95_RS10575	COG1216	Glycosyl transferase, family 2
KDJ95_RS10595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KDJ95_RS10595	COG2755	lipolytic protein G-D-S-L family
KDJ95_RS10615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KDJ95_RS10620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KDJ95_RS10620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KDJ95_RS10625	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KDJ95_RS10635	COG0280	phosphate acetyltransferase
KDJ95_RS10635	COG0281	malic enzyme
KDJ95_RS10650	COG1472	Belongs to the glycosyl hydrolase 3 family
KDJ95_RS10655	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KDJ95_RS10670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KDJ95_RS10680	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KDJ95_RS10685	COG1063	alcohol dehydrogenase
KDJ95_RS10700	COG0714	Associated with various cellular activities
KDJ95_RS10710	COG0193	aminoacyl-tRNA hydrolase activity
KDJ95_RS10715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KDJ95_RS10730	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KDJ95_RS10750	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
KDJ95_RS10765	COG0375	protein maturation
KDJ95_RS10790	COG0778	Nitroreductase
KDJ95_RS10795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KDJ95_RS10815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KDJ95_RS10815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KDJ95_RS10825	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KDJ95_RS10825	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KDJ95_RS10845	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KDJ95_RS10850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KDJ95_RS10855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KDJ95_RS10890	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KDJ95_RS10895	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KDJ95_RS10910	COG0318	PFAM AMP-dependent synthetase and ligase
KDJ95_RS10940	COG0339	signal peptide processing
KDJ95_RS10950	COG0018	arginyl-trna synthetase
KDJ95_RS10990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KDJ95_RS10995	COG0653	protein targeting
KDJ95_RS11010	COG0494	nUDIX hydrolase