locus-tag	class	description
AMUC_RS00015	COG0494	nUDIX hydrolase
AMUC_RS00020	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMUC_RS00025	COG1131	(ABC) transporter
AMUC_RS00045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AMUC_RS00050	COG0564	pseudouridine synthase activity
AMUC_RS00065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMUC_RS00070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMUC_RS00080	COG0513	Belongs to the DEAD box helicase family
AMUC_RS00095	COG0673	inositol 2-dehydrogenase activity
AMUC_RS00115	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AMUC_RS00160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMUC_RS00185	COG0442	prolyl-tRNA aminoacylation
AMUC_RS00210	COG0531	amino acid
AMUC_RS00215	COG2066	Belongs to the glutaminase family
AMUC_RS00230	COG1115	amino acid carrier protein
AMUC_RS00240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMUC_RS00245	COG2890	protein-(glutamine-N5) methyltransferase activity
AMUC_RS00250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AMUC_RS00255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMUC_RS00275	COG2226	methyltransferase
AMUC_RS00280	COG0534	Mate efflux family protein
AMUC_RS00300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AMUC_RS00325	COG1121	(ABC) transporter
AMUC_RS00330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMUC_RS00335	COG3880	PFAM UvrB UvrC protein
AMUC_RS00340	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AMUC_RS00345	COG0542	response to heat
AMUC_RS00380	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMUC_RS00385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMUC_RS00400	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMUC_RS00400	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMUC_RS00410	COG0180	Tryptophanyl-tRNA synthetase
AMUC_RS00420	COG1692	metallophosphoesterase
AMUC_RS00430	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AMUC_RS00445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMUC_RS00450	COG2816	NAD+ diphosphatase activity
AMUC_RS00465	COG0156	8-amino-7-oxononanoate synthase activity
AMUC_RS00520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AMUC_RS00535	COG3189	MarR family transcriptional regulator
AMUC_RS00545	COG0181	hydroxymethylbilane synthase activity
AMUC_RS00550	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMUC_RS00560	COG1469	GTP cyclohydrolase I activity
AMUC_RS00565	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMUC_RS00570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMUC_RS00580	COG1940	carbohydrate kinase activity
AMUC_RS00595	COG0494	nUDIX hydrolase
AMUC_RS00600	COG1566	PFAM secretion protein HlyD family protein
AMUC_RS00605	COG0577	efflux transmembrane transporter activity
AMUC_RS00605	COG1136	(ABC) transporter
AMUC_RS00610	COG0577	efflux transmembrane transporter activity
AMUC_RS00610	COG1136	(ABC) transporter
AMUC_RS00615	COG1538	Outer membrane efflux protein
AMUC_RS00640	COG1720	tRNA m6t6A37 methyltransferase activity
AMUC_RS00645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMUC_RS00650	COG0540	Belongs to the ATCase OTCase family
AMUC_RS00655	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AMUC_RS00675	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AMUC_RS00680	COG2957	Belongs to the agmatine deiminase family
AMUC_RS00690	COG0750	zinc metalloprotease
AMUC_RS00700	COG3119	arylsulfatase activity
AMUC_RS00710	COG1918	ferrous iron import across plasma membrane
AMUC_RS00710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AMUC_RS00780	COG1475	DNA binding
AMUC_RS00815	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMUC_RS00830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMUC_RS00835	COG0601	transmembrane transport
AMUC_RS00900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMUC_RS00905	COG1132	(ABC) transporter
AMUC_RS00910	COG1132	(ABC) transporter
AMUC_RS00925	COG1127	ABC transporter
AMUC_RS00930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMUC_RS00960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMUC_RS00975	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMUC_RS00980	COG0504	CTP synthase activity
AMUC_RS00985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMUC_RS01010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMUC_RS01020	COG1322	Protein conserved in bacteria
AMUC_RS01025	COG0546	phosphoglycolate phosphatase activity
AMUC_RS01030	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMUC_RS01040	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMUC_RS01070	COG2234	aminopeptidase activity
AMUC_RS01075	COG2755	lipolytic protein G-D-S-L family
AMUC_RS01075	COG0657	acetylesterase activity
AMUC_RS01080	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMUC_RS01100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMUC_RS01120	COG0335	large ribosomal subunit rRNA binding
AMUC_RS01130	COG0346	lactoylglutathione lyase activity
AMUC_RS01145	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AMUC_RS01150	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AMUC_RS01160	COG0427	acetyl-CoA hydrolase
AMUC_RS01170	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AMUC_RS01180	COG0205	6-phosphofructokinase activity
AMUC_RS01190	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMUC_RS01195	COG0028	Belongs to the TPP enzyme family
AMUC_RS01215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AMUC_RS01230	COG0471	metal ion transport
AMUC_RS01240	COG0351	phosphomethylpyrimidine kinase
AMUC_RS01295	COG1028	Short-chain dehydrogenase reductase Sdr
AMUC_RS01305	COG0242	peptide deformylase activity
AMUC_RS01310	COG1063	alcohol dehydrogenase
AMUC_RS01325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMUC_RS01330	COG1393	Belongs to the ArsC family
AMUC_RS01335	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AMUC_RS01345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMUC_RS01355	COG1187	pseudouridine synthase activity
AMUC_RS01360	COG0336	Belongs to the RNA methyltransferase TrmD family
AMUC_RS01365	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMUC_RS01375	COG0539	negative regulation of cytoplasmic translation
AMUC_RS01425	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AMUC_RS01430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AMUC_RS01435	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMUC_RS01440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMUC_RS01480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMUC_RS01505	COG0662	Cupin 2, conserved barrel domain protein
AMUC_RS01505	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMUC_RS01515	COG0416	fatty acid biosynthetic process
AMUC_RS01520	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMUC_RS01530	COG0537	adenosine 5'-monophosphoramidase activity
AMUC_RS01535	COG0009	L-threonylcarbamoyladenylate synthase
AMUC_RS01540	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMUC_RS01545	COG0228	four-way junction DNA binding
AMUC_RS01570	COG1862	Preprotein translocase
AMUC_RS01575	COG0343	queuine tRNA-ribosyltransferase activity
AMUC_RS01580	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMUC_RS01590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMUC_RS01595	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AMUC_RS01600	COG0776	regulation of translation
AMUC_RS01635	COG0811	peptide transport
AMUC_RS01655	COG3250	beta-galactosidase activity
AMUC_RS01660	COG0525	valine-tRNA ligase activity
AMUC_RS01675	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AMUC_RS01680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMUC_RS01685	COG0255	Belongs to the universal ribosomal protein uL29 family
AMUC_RS01690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMUC_RS01695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMUC_RS01700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AMUC_RS01710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMUC_RS01715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMUC_RS01720	COG0089	rRNA binding
AMUC_RS01725	COG0088	Forms part of the polypeptide exit tunnel
AMUC_RS01730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMUC_RS01735	COG0051	transcription antitermination factor activity, RNA binding
AMUC_RS01740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMUC_RS01745	COG0049	tRNA binding
AMUC_RS01750	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMUC_RS01755	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AMUC_RS01765	COG3852	Histidine kinase
AMUC_RS01770	COG2204	response regulator
AMUC_RS01780	COG1722	exodeoxyribonuclease VII activity
AMUC_RS01785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMUC_RS01800	COG0795	lipopolysaccharide-transporting ATPase activity
AMUC_RS01805	COG1160	GTP binding
AMUC_RS01810	COG0444	Belongs to the ABC transporter superfamily
AMUC_RS01875	COG0577	efflux transmembrane transporter activity
AMUC_RS01875	COG1136	(ABC) transporter
AMUC_RS01885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMUC_RS01930	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMUC_RS01940	COG0799	negative regulation of ribosome biogenesis
AMUC_RS02000	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AMUC_RS02020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AMUC_RS02030	COG0300	oxidoreductase activity
AMUC_RS02050	COG0038	chloride channel
AMUC_RS02075	COG0076	glutamate decarboxylase activity
AMUC_RS02090	COG0167	dihydroorotate dehydrogenase activity
AMUC_RS02095	COG0351	phosphomethylpyrimidine kinase
AMUC_RS02095	COG0352	thiamine-phosphate diphosphorylase activity
AMUC_RS02115	COG1253	flavin adenine dinucleotide binding
AMUC_RS02120	COG1253	flavin adenine dinucleotide binding
AMUC_RS02130	COG1185	polyribonucleotide nucleotidyltransferase activity
AMUC_RS02135	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMUC_RS02140	COG0110	maltose O-acetyltransferase activity
AMUC_RS02165	COG0101	tRNA pseudouridine synthase activity
AMUC_RS02170	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMUC_RS02190	COG4968	Prepilin-type N-terminal cleavage methylation domain
AMUC_RS02205	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AMUC_RS02210	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AMUC_RS02230	COG1136	(ABC) transporter
AMUC_RS02235	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AMUC_RS02245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMUC_RS02280	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMUC_RS02285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMUC_RS02300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AMUC_RS02305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMUC_RS02320	COG2814	Major facilitator Superfamily
AMUC_RS02335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMUC_RS02340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMUC_RS02340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMUC_RS02345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMUC_RS02355	COG0552	protein localization to endoplasmic reticulum
AMUC_RS02360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMUC_RS02380	COG1058	Belongs to the CinA family
AMUC_RS02380	COG1546	Belongs to the CinA family
AMUC_RS02390	COG0456	acetyltransferase
AMUC_RS02415	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMUC_RS02420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AMUC_RS02425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AMUC_RS02430	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AMUC_RS02445	COG0758	DNA mediated transformation
AMUC_RS02450	COG1686	Belongs to the peptidase S11 family
AMUC_RS02455	COG0012	GTP binding
AMUC_RS02460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMUC_RS02470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMUC_RS02470	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMUC_RS02485	COG3119	arylsulfatase activity
AMUC_RS02515	COG2259	Doxx family
AMUC_RS02520	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMUC_RS02550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMUC_RS02570	COG2326	polyphosphate kinase activity
AMUC_RS02575	COG1349	DNA-binding transcription factor activity
AMUC_RS02590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMUC_RS02595	COG1162	GTPase activity
AMUC_RS02610	COG0742	ribosomal rna small subunit methyltransferase
AMUC_RS02625	COG2326	polyphosphate kinase activity
AMUC_RS02640	COG5434	Belongs to the glycosyl hydrolase 28 family
AMUC_RS02650	COG1073	alpha beta
AMUC_RS02655	COG0802	atpase or kinase
AMUC_RS02660	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMUC_RS02665	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMUC_RS02670	COG0735	belongs to the Fur family
AMUC_RS02675	COG0396	ATPase activity
AMUC_RS02680	COG0719	Fe-S assembly protein
AMUC_RS02685	COG0719	Fe-S assembly protein
AMUC_RS02705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMUC_RS02750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMUC_RS02770	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMUC_RS02775	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMUC_RS02780	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMUC_RS02785	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMUC_RS02790	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMUC_RS02795	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMUC_RS02805	COG0356	it plays a direct role in the translocation of protons across the membrane
AMUC_RS02860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMUC_RS02885	COG1045	serine acetyltransferase
AMUC_RS02890	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMUC_RS02895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMUC_RS02905	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AMUC_RS02915	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMUC_RS02925	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMUC_RS02930	COG0047	phosphoribosylformylglycinamidine synthase activity
AMUC_RS02940	COG1363	Peptidase, m42
AMUC_RS02955	COG1077	Cell shape determining protein MreB Mrl
AMUC_RS02960	COG1530	ribonuclease E activity
AMUC_RS02985	COG0848	biopolymer transport protein
AMUC_RS03000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMUC_RS03025	COG0134	indole-3-glycerol-phosphate synthase activity
AMUC_RS03030	COG0792	nuclease activity
AMUC_RS03040	COG1253	flavin adenine dinucleotide binding
AMUC_RS03050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMUC_RS03065	COG0137	argininosuccinate synthase activity
AMUC_RS03080	COG0149	triose-phosphate isomerase activity
AMUC_RS03120	COG1040	competence protein
AMUC_RS03130	COG3956	TIGRFAM MazG family protein
AMUC_RS03155	COG1663	tetraacyldisaccharide 4'-kinase activity
AMUC_RS03160	COG0612	Peptidase, M16
AMUC_RS03180	COG0673	inositol 2-dehydrogenase activity
AMUC_RS03185	COG3034	peptidoglycan biosynthetic process
AMUC_RS03205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMUC_RS03210	COG0424	maF-like protein
AMUC_RS03215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMUC_RS03245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMUC_RS03255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMUC_RS03265	COG0571	ribonuclease III activity
AMUC_RS03275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AMUC_RS03315	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AMUC_RS03330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AMUC_RS03350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMUC_RS03355	COG0631	protein serine/threonine phosphatase activity
AMUC_RS03365	COG2226	methyltransferase
AMUC_RS03375	COG2076	Multidrug Resistance protein
AMUC_RS03425	COG2255	four-way junction helicase activity
AMUC_RS03430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMUC_RS03435	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMUC_RS03480	COG0438	transferase activity, transferring glycosyl groups
AMUC_RS03490	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMUC_RS03500	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMUC_RS03510	COG0482	sulfurtransferase activity
AMUC_RS03515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AMUC_RS03525	COG2860	membrane
AMUC_RS03530	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AMUC_RS03535	COG2001	Belongs to the MraZ family
AMUC_RS03540	COG0275	rRNA processing
AMUC_RS03550	COG0768	penicillin binding
AMUC_RS03555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMUC_RS03560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AMUC_RS03565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMUC_RS03570	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMUC_RS03580	COG0772	Belongs to the SEDS family
AMUC_RS03585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AMUC_RS03590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMUC_RS03595	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMUC_RS03605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AMUC_RS03610	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMUC_RS03615	COG0321	lipoyl(octanoyl) transferase activity
AMUC_RS03620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMUC_RS03625	COG0066	3-isopropylmalate dehydratase activity
AMUC_RS03635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMUC_RS03645	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMUC_RS03655	COG4608	Belongs to the ABC transporter superfamily
AMUC_RS03665	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMUC_RS03670	COG0052	Belongs to the universal ribosomal protein uS2 family
AMUC_RS03680	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AMUC_RS03695	COG1137	ATPase activity
AMUC_RS03705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMUC_RS03720	COG1733	regulation of RNA biosynthetic process
AMUC_RS03745	COG0017	Asparaginyl-tRNA synthetase
AMUC_RS03755	COG3118	belongs to the thioredoxin family
AMUC_RS03805	COG0583	DNA-binding transcription factor activity
AMUC_RS03810	COG2855	membrane
AMUC_RS03820	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AMUC_RS03835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMUC_RS03845	COG0602	queuosine metabolic process
AMUC_RS03855	COG0217	transcriptional regulatory protein
AMUC_RS03860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AMUC_RS03865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMUC_RS03865	COG4651	solute:proton antiporter activity
AMUC_RS03875	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AMUC_RS03880	COG4864	UPF0365 protein
AMUC_RS03890	COG2022	thiamine diphosphate biosynthetic process
AMUC_RS03895	COG0531	amino acid
AMUC_RS03905	COG0628	permease
AMUC_RS03910	COG0019	diaminopimelate decarboxylase activity
AMUC_RS03915	COG0191	fructose-bisphosphate aldolase activity
AMUC_RS03920	COG1217	gtp-binding protein TYPA
AMUC_RS03950	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMUC_RS03985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMUC_RS03990	COG0517	IMP dehydrogenase activity
AMUC_RS03990	COG0516	GMP reductase activity
AMUC_RS03995	COG0519	Catalyzes the synthesis of GMP from XMP
AMUC_RS03995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMUC_RS04005	COG0546	phosphoglycolate phosphatase activity
AMUC_RS04020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMUC_RS04035	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AMUC_RS04040	COG0196	riboflavin kinase activity
AMUC_RS04045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMUC_RS04060	COG1408	metallophosphoesterase
AMUC_RS04080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMUC_RS04105	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMUC_RS04105	COG2755	lipolytic protein G-D-S-L family
AMUC_RS04125	COG0471	metal ion transport
AMUC_RS04125	COG0490	domain, Protein
AMUC_RS04165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMUC_RS04175	COG0477	Major facilitator Superfamily
AMUC_RS04180	COG1607	acyl-coa hydrolase
AMUC_RS04190	COG1028	Short-chain dehydrogenase reductase Sdr
AMUC_RS04200	COG1525	nuclease
AMUC_RS04215	COG1475	DNA binding
AMUC_RS04220	COG3969	phosphoadenosine phosphosulfate
AMUC_RS04235	COG0473	3-isopropylmalate dehydrogenase activity
AMUC_RS04260	COG2873	o-acetylhomoserine
AMUC_RS04265	COG0535	radical SAM domain protein
AMUC_RS04270	COG0535	radical SAM domain protein
AMUC_RS04285	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMUC_RS04290	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMUC_RS04305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMUC_RS04315	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMUC_RS04315	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMUC_RS04315	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMUC_RS04315	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AMUC_RS04325	COG1733	regulation of RNA biosynthetic process
AMUC_RS04335	COG0107	imidazoleglycerol-phosphate synthase activity
AMUC_RS04345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMUC_RS04355	COG1643	Atp-dependent helicase
AMUC_RS04360	COG0440	acetolactate synthase activity
AMUC_RS04365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMUC_RS04380	COG0445	tRNA wobble uridine modification
AMUC_RS04385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMUC_RS04385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMUC_RS04400	COG0592	DNA-directed DNA polymerase activity
AMUC_RS04425	COG1388	LysM domain
AMUC_RS04425	COG0791	NLP P60 protein
AMUC_RS04430	COG0084	hydrolase, TatD family'
AMUC_RS04440	COG3250	beta-galactosidase activity
AMUC_RS04455	COG2205	protein histidine kinase activity
AMUC_RS04460	COG0745	RESPONSE REGULATOR receiver
AMUC_RS04470	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AMUC_RS04500	COG0542	response to heat
AMUC_RS04545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMUC_RS04555	COG0659	secondary active sulfate transmembrane transporter activity
AMUC_RS04560	COG0165	Argininosuccinate lyase
AMUC_RS04575	COG0148	phosphopyruvate hydratase activity
AMUC_RS04580	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AMUC_RS04590	COG3481	metal-dependent phosphohydrolase, HD sub domain
AMUC_RS04600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMUC_RS04605	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMUC_RS04635	COG0490	domain, Protein
AMUC_RS04635	COG2985	domain, Protein
AMUC_RS04650	COG0471	metal ion transport
AMUC_RS04675	COG2194	sulfuric ester hydrolase activity
AMUC_RS04685	COG1592	Rubrerythrin
AMUC_RS04695	COG1363	Peptidase, m42
AMUC_RS04700	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AMUC_RS04710	COG1785	Belongs to the alkaline phosphatase family
AMUC_RS04715	COG1970	mechanosensitive ion channel activity
AMUC_RS04720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMUC_RS04730	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMUC_RS04740	COG2217	Heavy metal translocating P-type atpase
AMUC_RS04745	COG0497	DNA recombination
AMUC_RS04750	COG0321	lipoyl(octanoyl) transferase activity
AMUC_RS04750	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AMUC_RS04755	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AMUC_RS04785	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMUC_RS04790	COG0022	dehydrogenase e1 component
AMUC_RS04795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMUC_RS04810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMUC_RS04815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMUC_RS04880	COG5632	N-Acetylmuramoyl-L-alanine amidase
AMUC_RS04880	COG3409	Peptidoglycan-binding domain 1 protein
AMUC_RS04885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AMUC_RS04910	COG1690	Belongs to the RtcB family
AMUC_RS04920	COG2814	Major facilitator Superfamily
AMUC_RS04930	COG2096	Adenosyltransferase
AMUC_RS04940	COG0557	exoribonuclease II activity
AMUC_RS04955	COG0826	peptidase U32
AMUC_RS04960	COG0285	dihydrofolate synthase activity
AMUC_RS04970	COG0673	inositol 2-dehydrogenase activity
AMUC_RS04975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMUC_RS04980	COG0737	Belongs to the 5'-nucleotidase family
AMUC_RS04990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMUC_RS04995	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMUC_RS05010	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMUC_RS05015	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMUC_RS05020	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AMUC_RS05025	COG0200	Binds to the 23S rRNA
AMUC_RS05030	COG0201	protein transport
AMUC_RS05035	COG0563	adenylate kinase activity
AMUC_RS05040	COG0024	Methionine aminopeptidase
AMUC_RS05055	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AMUC_RS05060	COG1442	glycosyl transferase family 8
AMUC_RS05080	COG1216	Glycosyl transferase, family 2
AMUC_RS05100	COG0693	protein deglycase activity
AMUC_RS05110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AMUC_RS05115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMUC_RS05125	COG1966	Carbon starvation protein
AMUC_RS05140	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AMUC_RS05145	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AMUC_RS05150	COG0195	Participates in both transcription termination and antitermination
AMUC_RS05155	COG0708	Exodeoxyribonuclease III
AMUC_RS05160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMUC_RS05165	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AMUC_RS05170	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMUC_RS05180	COG1716	ATPase activity
AMUC_RS05180	COG1131	(ABC) transporter
AMUC_RS05180	COG0842	Transport permease protein
AMUC_RS05205	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMUC_RS05225	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMUC_RS05235	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AMUC_RS05240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMUC_RS05255	COG1490	D-aminoacyl-tRNA deacylase activity
AMUC_RS05285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMUC_RS05290	COG1053	succinate dehydrogenase
AMUC_RS05340	COG1028	Short-chain dehydrogenase reductase Sdr
AMUC_RS05350	COG0488	(ABC) transporter
AMUC_RS05360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AMUC_RS05370	COG1253	flavin adenine dinucleotide binding
AMUC_RS05375	COG1028	Short-chain dehydrogenase reductase Sdr
AMUC_RS05390	COG1073	alpha beta
AMUC_RS05455	COG2267	carboxylic ester hydrolase activity
AMUC_RS05460	COG2095	MarC family integral membrane protein
AMUC_RS05500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMUC_RS05505	COG0488	(ABC) transporter
AMUC_RS05515	COG0697	spore germination
AMUC_RS05525	COG0215	cysteine-tRNA ligase activity
AMUC_RS05535	COG3119	arylsulfatase activity
AMUC_RS05550	COG0481	GTPase activity
AMUC_RS05565	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMUC_RS05570	COG0085	RNA polymerase activity
AMUC_RS05575	COG0222	ribosome binding
AMUC_RS05580	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMUC_RS05585	COG0081	regulation of translation
AMUC_RS05590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMUC_RS05595	COG0250	Participates in transcription elongation, termination and antitermination
AMUC_RS05610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMUC_RS05620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMUC_RS05630	COG0740	serine-type endopeptidase activity
AMUC_RS05635	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMUC_RS05650	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AMUC_RS05670	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMUC_RS05715	COG2226	methyltransferase
AMUC_RS05720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMUC_RS05725	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMUC_RS05745	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMUC_RS05745	COG1902	pentaerythritol trinitrate reductase activity
AMUC_RS05755	COG3119	arylsulfatase activity
AMUC_RS05760	COG0514	ATP-dependent DNA helicase (RecQ)
AMUC_RS05790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMUC_RS05795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMUC_RS05840	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AMUC_RS05855	COG1858	cytochrome C peroxidase
AMUC_RS05860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMUC_RS05865	COG0590	tRNA wobble adenosine to inosine editing
AMUC_RS05870	COG1940	carbohydrate kinase activity
AMUC_RS05875	COG2217	Heavy metal translocating P-type atpase
AMUC_RS05880	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMUC_RS05915	COG1363	Peptidase, m42
AMUC_RS05930	COG0006	proline dipeptidase activity
AMUC_RS05935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMUC_RS05955	COG0745	RESPONSE REGULATOR receiver
AMUC_RS05960	COG0129	dihydroxy-acid dehydratase activity
AMUC_RS05985	COG1368	sulfuric ester hydrolase activity
AMUC_RS06020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMUC_RS06025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMUC_RS06045	COG0534	Mate efflux family protein
AMUC_RS06050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMUC_RS06065	COG1876	peptidase activity
AMUC_RS06110	COG3209	COG3209 Rhs family protein
AMUC_RS06140	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AMUC_RS06145	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AMUC_RS06150	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AMUC_RS06155	COG2205	protein histidine kinase activity
AMUC_RS06165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMUC_RS06175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMUC_RS06190	COG0667	Aldo Keto reductase
AMUC_RS06195	COG0789	Transcriptional regulator
AMUC_RS06245	COG0714	Associated with various cellular activities
AMUC_RS06250	COG2311	Membrane
AMUC_RS06275	COG1090	epimerase
AMUC_RS06290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AMUC_RS06295	COG1119	ATPase activity
AMUC_RS06300	COG2186	Transcriptional regulator
AMUC_RS06320	COG0148	phosphopyruvate hydratase activity
AMUC_RS06325	COG0436	Aminotransferase
AMUC_RS06330	COG1477	protein flavinylation
AMUC_RS06345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMUC_RS06360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMUC_RS06380	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMUC_RS06390	COG1199	ATP-dependent helicase activity
AMUC_RS06395	COG1122	ATPase activity
AMUC_RS06420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMUC_RS06425	COG0598	Magnesium transport protein CorA
AMUC_RS06430	COG0359	binds to the 23S rRNA
AMUC_RS06435	COG0138	bifunctional purine biosynthesis protein purh
AMUC_RS06440	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMUC_RS06445	COG0736	holo-[acyl-carrier-protein] synthase activity
AMUC_RS06455	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AMUC_RS06460	COG3409	Peptidoglycan-binding domain 1 protein
AMUC_RS06460	COG5632	N-Acetylmuramoyl-L-alanine amidase
AMUC_RS06465	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMUC_RS06475	COG0437	4 iron, 4 sulfur cluster binding
AMUC_RS06500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMUC_RS06550	COG0284	orotidine-5'-phosphate decarboxylase activity
AMUC_RS06570	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMUC_RS06575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AMUC_RS06595	COG2003	Belongs to the UPF0758 family
AMUC_RS06610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMUC_RS06615	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMUC_RS06620	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMUC_RS06625	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMUC_RS06630	COG0322	excinuclease ABC activity
AMUC_RS06635	COG0811	peptide transport
AMUC_RS06640	COG0848	biopolymer transport protein
AMUC_RS06650	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMUC_RS06655	COG0483	inositol monophosphate 1-phosphatase activity
AMUC_RS06660	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMUC_RS06670	COG1482	cell wall glycoprotein biosynthetic process
AMUC_RS06680	COG1757	Na H antiporter
AMUC_RS06685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMUC_RS06690	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AMUC_RS06695	COG0505	Belongs to the CarA family
AMUC_RS06700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMUC_RS06715	COG0067	glutamate synthase
AMUC_RS06715	COG0070	glutamate synthase
AMUC_RS06715	COG0069	glutamate synthase activity
AMUC_RS06730	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AMUC_RS06735	COG0594	ribonuclease P activity
AMUC_RS06740	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AMUC_RS06760	COG0676	glucose-6-phosphate 1-epimerase activity
AMUC_RS06765	COG0259	pyridoxamine-phosphate oxidase activity
AMUC_RS06780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMUC_RS06800	COG1760	l-serine dehydratase
AMUC_RS06805	COG3118	belongs to the thioredoxin family
AMUC_RS06805	COG0492	ferredoxin-NADP+ reductase activity
AMUC_RS06855	COG1408	metallophosphoesterase
AMUC_RS06865	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AMUC_RS06870	COG0545	Peptidyl-prolyl cis-trans isomerase
AMUC_RS06890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AMUC_RS06900	COG0826	peptidase U32
AMUC_RS06905	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMUC_RS06925	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMUC_RS06935	COG1116	anion transmembrane transporter activity
AMUC_RS06945	COG0529	Catalyzes the synthesis of activated sulfate
AMUC_RS06945	COG2895	sulfate adenylyltransferase (ATP) activity
AMUC_RS06950	COG0175	sulfate reduction
AMUC_RS06955	COG0175	sulfate reduction
AMUC_RS06975	COG0581	inorganic phosphate transmembrane transporter activity
AMUC_RS06980	COG0573	inorganic phosphate transmembrane transporter activity
AMUC_RS06990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMUC_RS07000	COG2017	converts alpha-aldose to the beta-anomer
AMUC_RS07015	COG0612	Peptidase, M16
AMUC_RS07050	COG0233	cytoplasmic translational termination
AMUC_RS07055	COG0528	UMP kinase activity
AMUC_RS07060	COG0668	transmembrane transport
AMUC_RS07065	COG0450	alkyl hydroperoxide reductase
AMUC_RS07070	COG0733	neurotransmitter:sodium symporter activity
AMUC_RS07085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMUC_RS07095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMUC_RS07100	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMUC_RS07105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMUC_RS07345	COG0842	Transport permease protein
AMUC_RS07350	COG0842	Transport permease protein
AMUC_RS07355	COG1131	(ABC) transporter
AMUC_RS07365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMUC_RS07370	COG1183	phosphatidylcholine synthase activity
AMUC_RS07380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMUC_RS07390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AMUC_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
AMUC_RS07420	COG0156	8-amino-7-oxononanoate synthase activity
AMUC_RS07450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMUC_RS07455	COG0124	histidyl-tRNA synthetase
AMUC_RS07460	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AMUC_RS07465	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AMUC_RS07470	COG0298	carbon dioxide binding
AMUC_RS07510	COG0443	Heat shock 70 kDa protein
AMUC_RS07515	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMUC_RS07520	COG0459	protein refolding
AMUC_RS07570	COG0632	four-way junction helicase activity
AMUC_RS07580	COG0126	phosphoglycerate kinase activity
AMUC_RS07595	COG1082	Xylose isomerase domain protein TIM barrel
AMUC_RS07610	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMUC_RS07620	COG2271	Major facilitator Superfamily
AMUC_RS07635	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AMUC_RS07650	COG0254	rRNA binding
AMUC_RS07685	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AMUC_RS07690	COG0039	L-malate dehydrogenase activity
AMUC_RS07715	COG0778	Nitroreductase
AMUC_RS07720	COG0564	pseudouridine synthase activity
AMUC_RS07745	COG1126	abc transporter atp-binding protein
AMUC_RS07750	COG0765	amino acid transport
AMUC_RS07760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMUC_RS07765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AMUC_RS07785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMUC_RS07810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AMUC_RS07815	COG1872	DUF167
AMUC_RS07820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMUC_RS07825	COG0484	heat shock protein binding
AMUC_RS07830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMUC_RS07840	COG5434	Belongs to the glycosyl hydrolase 28 family
AMUC_RS07855	COG0277	FAD linked oxidase domain protein
AMUC_RS07880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMUC_RS07885	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AMUC_RS07900	COG0131	Imidazoleglycerol-phosphate dehydratase
AMUC_RS07905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMUC_RS07910	COG0360	Binds together with S18 to 16S ribosomal RNA
AMUC_RS07915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMUC_RS07930	COG1686	Belongs to the peptidase S11 family
AMUC_RS07935	COG0205	6-phosphofructokinase activity
AMUC_RS07945	COG0428	transporter
AMUC_RS07950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMUC_RS07965	COG3977	Valine--pyruvate aminotransferase
AMUC_RS07970	COG1561	YicC-like family, N-terminal region
AMUC_RS07980	COG0471	metal ion transport
AMUC_RS07980	COG3273	potassium ion transport
AMUC_RS07985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMUC_RS08000	COG1575	Belongs to the MenA family. Type 1 subfamily
AMUC_RS08040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMUC_RS08040	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMUC_RS08060	COG0202	RNA polymerase activity
AMUC_RS08065	COG0203	ribosomal protein L17
AMUC_RS08070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMUC_RS08080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMUC_RS08095	COG2885	chlorophyll binding
AMUC_RS08130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMUC_RS08165	COG0667	Aldo Keto reductase
AMUC_RS08170	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AMUC_RS08190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMUC_RS08195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMUC_RS08200	COG0134	indole-3-glycerol-phosphate synthase activity
AMUC_RS08205	COG0135	phosphoribosylanthranilate isomerase activity
AMUC_RS08215	COG0159	tryptophan synthase activity
AMUC_RS08235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMUC_RS08240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMUC_RS08250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMUC_RS08285	COG0561	phosphatase activity
AMUC_RS08295	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMUC_RS08300	COG2223	nitrite transmembrane transporter activity
AMUC_RS08320	COG0556	nucleotide-excision repair
AMUC_RS08325	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AMUC_RS08330	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMUC_RS08335	COG0750	zinc metalloprotease
AMUC_RS08350	COG1074	ATP-dependent DNA helicase activity
AMUC_RS08365	COG0697	spore germination
AMUC_RS08375	COG2373	Large extracellular alpha-helical protein
AMUC_RS08380	COG1979	alcohol dehydrogenase
AMUC_RS08390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMUC_RS08415	COG0372	Belongs to the citrate synthase family
AMUC_RS08430	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMUC_RS08440	COG1187	pseudouridine synthase activity
AMUC_RS08450	COG0105	UTP biosynthetic process
AMUC_RS08455	COG1215	transferase activity, transferring glycosyl groups
AMUC_RS08460	COG0463	Glycosyl transferase, family 2
AMUC_RS08470	COG1459	type II secretion system
AMUC_RS08475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMUC_RS08480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMUC_RS08485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMUC_RS08500	COG0728	peptidoglycan biosynthetic process
AMUC_RS08505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMUC_RS08505	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMUC_RS08515	COG1649	PFAM Uncharacterised BCR, COG1649
AMUC_RS08520	COG1691	(AIR) carboxylase
AMUC_RS08525	COG0037	tRNA processing
AMUC_RS08530	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AMUC_RS08535	COG0142	geranyltranstransferase activity
AMUC_RS08550	COG2151	metal-sulfur cluster biosynthetic enzyme
AMUC_RS08565	COG1007	ATP synthesis coupled electron transport
AMUC_RS08570	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMUC_RS08580	COG0713	ATP synthesis coupled electron transport
AMUC_RS08595	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMUC_RS08600	COG1034	ATP synthesis coupled electron transport
AMUC_RS08605	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AMUC_RS08610	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AMUC_RS08615	COG0649	NAD binding
AMUC_RS08625	COG0726	polysaccharide deacetylase
AMUC_RS08635	COG0307	riboflavin synthase, alpha
AMUC_RS08645	COG2264	protein methyltransferase activity
AMUC_RS08650	COG3210	domain, Protein
AMUC_RS08655	COG1640	4-alpha-glucanotransferase
AMUC_RS08670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMUC_RS08675	COG1030	water channel activity
AMUC_RS08685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMUC_RS08690	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AMUC_RS08705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMUC_RS08710	COG0793	Belongs to the peptidase S41A family
AMUC_RS08725	COG1643	Atp-dependent helicase
AMUC_RS08750	COG1450	Type ii and iii secretion system protein
AMUC_RS08765	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMUC_RS08785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMUC_RS08790	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMUC_RS08800	COG0268	Binds directly to 16S ribosomal RNA
AMUC_RS08805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMUC_RS08810	COG0028	Belongs to the TPP enzyme family
AMUC_RS08820	COG0688	phosphatidylethanolamine metabolic process
AMUC_RS08825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AMUC_RS08830	COG0495	leucyl-tRNA aminoacylation
AMUC_RS08835	COG3119	arylsulfatase activity
AMUC_RS08850	COG1166	arginine decarboxylase activity
AMUC_RS08885	COG3250	beta-galactosidase activity
AMUC_RS08890	COG3250	beta-galactosidase activity
AMUC_RS08895	COG3250	beta-galactosidase activity
AMUC_RS08900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMUC_RS08905	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AMUC_RS08925	COG0205	6-phosphofructokinase activity
AMUC_RS08970	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AMUC_RS08975	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AMUC_RS08980	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AMUC_RS08995	COG4771	TonB-dependent receptor
AMUC_RS09015	COG0402	S-adenosylhomocysteine deaminase activity
AMUC_RS09020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMUC_RS09045	COG1294	oxidase, subunit
AMUC_RS09050	COG1271	oxidase subunit
AMUC_RS09060	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMUC_RS09080	COG1846	Transcriptional regulator
AMUC_RS09105	COG2949	membrane
AMUC_RS09135	COG0514	ATP-dependent DNA helicase (RecQ)
AMUC_RS09150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AMUC_RS09155	COG0045	succinate-CoA ligase (ADP-forming) activity
AMUC_RS09160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMUC_RS09225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMUC_RS09230	COG2205	protein histidine kinase activity
AMUC_RS09245	COG0113	porphobilinogen synthase activity
AMUC_RS09260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMUC_RS09280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AMUC_RS09320	COG3475	LICD family
AMUC_RS09325	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMUC_RS09335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMUC_RS09350	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMUC_RS09360	COG2166	iron-sulfur cluster assembly
AMUC_RS09365	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMUC_RS09375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMUC_RS09380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMUC_RS09385	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AMUC_RS09390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMUC_RS09395	COG1131	(ABC) transporter
AMUC_RS09410	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AMUC_RS09425	COG1215	transferase activity, transferring glycosyl groups
AMUC_RS09445	COG1522	sequence-specific DNA binding
AMUC_RS09450	COG0436	Aminotransferase
AMUC_RS09465	COG0423	glycine-tRNA ligase activity
AMUC_RS09470	COG0656	L-ascorbic acid biosynthetic process
AMUC_RS09485	COG2304	oxidoreductase activity
AMUC_RS09500	COG0714	Associated with various cellular activities
AMUC_RS09505	COG0154	amidase activity
AMUC_RS09510	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMUC_RS09550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMUC_RS09555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMUC_RS09565	COG2755	lipolytic protein G-D-S-L family
AMUC_RS09565	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMUC_RS09595	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMUC_RS09605	COG0656	L-ascorbic acid biosynthetic process
AMUC_RS09615	COG0667	Aldo Keto reductase
AMUC_RS09620	COG1408	metallophosphoesterase
AMUC_RS09640	COG0667	Aldo Keto reductase
AMUC_RS09650	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMUC_RS09655	COG0789	Transcriptional regulator
AMUC_RS09675	COG0534	Mate efflux family protein
AMUC_RS09695	COG1091	dTDP-4-dehydrorhamnose reductase activity
AMUC_RS09710	COG1837	Belongs to the UPF0109 family
AMUC_RS09720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMUC_RS09725	COG0363	glucosamine-6-phosphate deaminase activity
AMUC_RS09745	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AMUC_RS09755	COG1741	Belongs to the pirin family
AMUC_RS09775	COG1070	Carbohydrate kinase
AMUC_RS09790	COG0738	Major facilitator superfamily
AMUC_RS09805	COG1595	DNA-templated transcription, initiation
AMUC_RS09830	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AMUC_RS09855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMUC_RS09870	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMUC_RS09880	COG0697	spore germination
AMUC_RS09890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMUC_RS09895	COG4608	Belongs to the ABC transporter superfamily
AMUC_RS09900	COG0444	Belongs to the ABC transporter superfamily
AMUC_RS09905	COG4166	transmembrane transport
AMUC_RS09915	COG0601	transmembrane transport
AMUC_RS09935	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMUC_RS09940	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AMUC_RS09945	COG3738	Protein conserved in bacteria
AMUC_RS09950	COG0151	Belongs to the GarS family
AMUC_RS09965	COG0811	peptide transport
AMUC_RS09975	COG0242	peptide deformylase activity
AMUC_RS10030	COG3274	enterobacterial common antigen metabolic process
AMUC_RS10035	COG0538	isocitrate dehydrogenase activity
AMUC_RS10055	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AMUC_RS10060	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMUC_RS10065	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AMUC_RS10075	COG0668	transmembrane transport
AMUC_RS10080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMUC_RS10080	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AMUC_RS10090	COG1968	undecaprenyl-diphosphatase activity
AMUC_RS10110	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMUC_RS10120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMUC_RS10130	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMUC_RS10140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMUC_RS10150	COG1408	metallophosphoesterase
AMUC_RS10175	COG4974	Belongs to the 'phage' integrase family
AMUC_RS10200	COG1454	alcohol dehydrogenase
AMUC_RS10205	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AMUC_RS10220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMUC_RS10235	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AMUC_RS10235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMUC_RS10240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMUC_RS10280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMUC_RS10290	COG4607	ABC-type enterochelin transport system periplasmic component
AMUC_RS10295	COG4604	ABC transporter, ATP-binding protein
AMUC_RS10300	COG4605	iron ion homeostasis
AMUC_RS10305	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMUC_RS10340	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMUC_RS10340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMUC_RS10360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMUC_RS10370	COG2195	Cleaves the N-terminal amino acid of tripeptides
AMUC_RS10390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMUC_RS10405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMUC_RS10430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMUC_RS10430	COG0519	Catalyzes the synthesis of GMP from XMP
AMUC_RS10435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMUC_RS10465	COG1410	methionine synthase
AMUC_RS10465	COG0646	methionine synthase
AMUC_RS10470	COG2966	Psort location CytoplasmicMembrane, score
AMUC_RS10475	COG3610	response to peptide
AMUC_RS10490	COG0460	homoserine dehydrogenase
AMUC_RS10495	COG0527	aspartate kinase activity
AMUC_RS10505	COG5522	Integral membrane protein (intg_mem_TP0381)
AMUC_RS10520	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMUC_RS10530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMUC_RS10535	COG1194	a g-specific adenine glycosylase
AMUC_RS10540	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AMUC_RS10545	COG0574	Belongs to the PEP-utilizing enzyme family
AMUC_RS10545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMUC_RS10555	COG0166	Belongs to the GPI family
AMUC_RS10565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMUC_RS10585	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMUC_RS10585	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMUC_RS10620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMUC_RS10625	COG2818	Glycosylase
AMUC_RS10645	COG3033	Beta-eliminating lyase
AMUC_RS10660	COG0072	phenylalanine-tRNA ligase activity
AMUC_RS10660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMUC_RS10680	COG0326	Molecular chaperone. Has ATPase activity
AMUC_RS10685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMUC_RS10705	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AMUC_RS10720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMUC_RS10725	COG1959	2 iron, 2 sulfur cluster binding
AMUC_RS10740	COG0352	thiamine-phosphate diphosphorylase activity
AMUC_RS10745	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AMUC_RS10770	COG1703	isobutyryl-CoA mutase activity
AMUC_RS10790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AMUC_RS10805	COG0418	dihydroorotase activity
AMUC_RS10825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMUC_RS10845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMUC_RS10860	COG0534	Mate efflux family protein
AMUC_RS10865	COG0489	protein tyrosine kinase activity
AMUC_RS10880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMUC_RS10885	COG0339	signal peptide processing
AMUC_RS10890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMUC_RS10900	COG1538	Outer membrane efflux protein
AMUC_RS10915	COG4112	unkown
AMUC_RS10930	COG0038	chloride channel
AMUC_RS10950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AMUC_RS10955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMUC_RS10960	COG0586	Pfam SNARE associated Golgi protein
AMUC_RS11035	COG1012	belongs to the aldehyde dehydrogenase family
AMUC_RS11055	COG0753	catalase activity
AMUC_RS11065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMUC_RS11070	COG1592	Rubrerythrin
AMUC_RS11075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMUC_RS11085	COG1674	ftsk spoiiie
AMUC_RS11095	COG0489	protein tyrosine kinase activity
AMUC_RS11105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMUC_RS11125	COG0438	transferase activity, transferring glycosyl groups
AMUC_RS11165	COG0110	maltose O-acetyltransferase activity
AMUC_RS11195	COG2755	lipolytic protein G-D-S-L family
AMUC_RS11195	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMUC_RS11215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMUC_RS11220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMUC_RS11220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMUC_RS11225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AMUC_RS11245	COG0281	malic enzyme
AMUC_RS11245	COG0280	phosphate acetyltransferase
AMUC_RS11260	COG1472	Belongs to the glycosyl hydrolase 3 family
AMUC_RS11265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMUC_RS11280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMUC_RS11290	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMUC_RS11295	COG1063	alcohol dehydrogenase
AMUC_RS11310	COG0714	Associated with various cellular activities
AMUC_RS11320	COG0193	aminoacyl-tRNA hydrolase activity
AMUC_RS11325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMUC_RS11340	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMUC_RS11365	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AMUC_RS11380	COG0375	protein maturation
AMUC_RS11405	COG0778	Nitroreductase
AMUC_RS11410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMUC_RS11430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMUC_RS11430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMUC_RS11440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AMUC_RS11440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AMUC_RS11460	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AMUC_RS11465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMUC_RS11470	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AMUC_RS11505	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMUC_RS11510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMUC_RS11555	COG0339	signal peptide processing
AMUC_RS11565	COG0018	arginyl-trna synthetase
AMUC_RS11600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMUC_RS11605	COG0653	protein targeting
AMUC_RS11630	COG1971	Probably functions as a manganese efflux pump
AMUC_RS11640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMUC_RS11645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMUC_RS11650	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AMUC_RS11655	COG0515	serine threonine protein kinase
AMUC_RS11655	COG3266	domain, Protein
AMUC_RS11660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMUC_RS11670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMUC_RS11715	COG2267	carboxylic ester hydrolase activity
AMUC_RS11720	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AMUC_RS11720	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AMUC_RS11750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMUC_RS11765	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AMUC_RS11780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMUC_RS11825	COG1215	transferase activity, transferring glycosyl groups
AMUC_RS11830	COG0463	Glycosyl transferase, family 2
AMUC_RS11830	COG1216	Glycosyl transferase, family 2
AMUC_RS11840	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMUC_RS11855	COG1442	glycosyl transferase family 8
AMUC_RS11855	COG1216	Glycosyl transferase, family 2
AMUC_RS11860	COG1216	Glycosyl transferase, family 2
AMUC_RS11880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AMUC_RS11905	COG0789	Transcriptional regulator
AMUC_RS11930	COG1216	Glycosyl transferase, family 2
AMUC_RS11935	COG1216	Glycosyl transferase, family 2
AMUC_RS11940	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMUC_RS11945	COG3119	arylsulfatase activity
AMUC_RS11950	COG0724	RNA recognition motif
AMUC_RS11975	COG0237	dephospho-CoA kinase activity
AMUC_RS11980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMUC_RS12010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AMUC_RS12010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMUC_RS12020	COG0706	membrane insertase activity
AMUC_RS12025	COG0657	acetylesterase activity
AMUC_RS12025	COG2755	lipolytic protein G-D-S-L family
AMUC_RS12045	COG0305	Participates in initiation and elongation during chromosome replication
AMUC_RS12050	COG0438	transferase activity, transferring glycosyl groups
AMUC_RS12055	COG0515	serine threonine protein kinase
AMUC_RS12055	COG2815	serine threonine protein kinase
AMUC_RS12065	COG0037	tRNA processing
AMUC_RS12095	COG0839	Belongs to the complex I subunit 6 family
AMUC_RS12100	COG0358	DNA primase activity
AMUC_RS12125	COG3475	LICD family
AMUC_RS12130	COG2967	ApaG domain
AMUC_RS12160	COG4239	(ABC) transporter, permease
AMUC_RS12165	COG2010	Cytochrome c
AMUC_RS12170	COG3258	Cytochrome c
AMUC_RS12175	COG0805	protein transport
AMUC_RS12205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMUC_RS12225	COG0438	transferase activity, transferring glycosyl groups
AMUC_RS12235	COG1216	Glycosyl transferase, family 2
AMUC_RS12250	COG0318	PFAM AMP-dependent synthetase and ligase