locus-tag	class	description
J5W76_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5W76_RS00010	COG1131	(ABC) transporter
J5W76_RS00030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J5W76_RS00035	COG0564	pseudouridine synthase activity
J5W76_RS00040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W76_RS00045	COG0077	Prephenate dehydratase
J5W76_RS00045	COG1605	Chorismate mutase
J5W76_RS00055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5W76_RS00060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J5W76_RS00065	COG0513	Belongs to the DEAD box helicase family
J5W76_RS00075	COG0673	inositol 2-dehydrogenase activity
J5W76_RS00100	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J5W76_RS00115	COG1971	Probably functions as a manganese efflux pump
J5W76_RS00135	COG0657	acetylesterase activity
J5W76_RS00135	COG2755	lipolytic protein G-D-S-L family
J5W76_RS00175	COG0442	prolyl-tRNA aminoacylation
J5W76_RS00225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5W76_RS00230	COG0402	S-adenosylhomocysteine deaminase activity
J5W76_RS00250	COG4771	TonB-dependent receptor
J5W76_RS00285	COG3896	Chloramphenicol phosphotransferase-like protein
J5W76_RS00300	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J5W76_RS00305	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J5W76_RS00345	COG0205	6-phosphofructokinase activity
J5W76_RS00360	COG1228	amidohydrolase
J5W76_RS00370	COG1335	isochorismatase
J5W76_RS00375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W76_RS00380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5W76_RS00385	COG3250	beta-galactosidase activity
J5W76_RS00390	COG3250	beta-galactosidase activity
J5W76_RS00395	COG3250	beta-galactosidase activity
J5W76_RS00405	COG1166	arginine decarboxylase activity
J5W76_RS00425	COG0495	leucyl-tRNA aminoacylation
J5W76_RS00430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J5W76_RS00450	COG0028	Belongs to the TPP enzyme family
J5W76_RS00455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W76_RS00460	COG0268	Binds directly to 16S ribosomal RNA
J5W76_RS00470	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5W76_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W76_RS00505	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5W76_RS00520	COG1450	Type ii and iii secretion system protein
J5W76_RS00530	COG0617	tRNA 3'-terminal CCA addition
J5W76_RS00545	COG1643	Atp-dependent helicase
J5W76_RS00550	COG0575	Belongs to the CDS family
J5W76_RS00555	COG0793	Belongs to the peptidase S41A family
J5W76_RS00560	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5W76_RS00575	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
J5W76_RS00585	COG0358	DNA primase activity
J5W76_RS00590	COG1030	water channel activity
J5W76_RS00595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W76_RS00605	COG1640	4-alpha-glucanotransferase
J5W76_RS00625	COG0307	riboflavin synthase, alpha
J5W76_RS00635	COG0726	polysaccharide deacetylase
J5W76_RS00640	COG0649	NAD binding
J5W76_RS00645	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J5W76_RS00650	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J5W76_RS00655	COG1034	ATP synthesis coupled electron transport
J5W76_RS00660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J5W76_RS00670	COG0839	Belongs to the complex I subunit 6 family
J5W76_RS00675	COG0713	ATP synthesis coupled electron transport
J5W76_RS00680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J5W76_RS00685	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W76_RS00690	COG1007	ATP synthesis coupled electron transport
J5W76_RS00710	COG2151	metal-sulfur cluster biosynthetic enzyme
J5W76_RS00725	COG0142	geranyltranstransferase activity
J5W76_RS00730	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
J5W76_RS00735	COG1606	tRNA processing
J5W76_RS00740	COG1691	(AIR) carboxylase
J5W76_RS00745	COG1649	PFAM Uncharacterised BCR, COG1649
J5W76_RS00755	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W76_RS00755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W76_RS00760	COG0728	peptidoglycan biosynthetic process
J5W76_RS00790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W76_RS00800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5W76_RS00805	COG1459	type II secretion system
J5W76_RS00815	COG0463	Glycosyl transferase, family 2
J5W76_RS00820	COG1215	transferase activity, transferring glycosyl groups
J5W76_RS00825	COG0105	UTP biosynthetic process
J5W76_RS00835	COG1187	pseudouridine synthase activity
J5W76_RS00845	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5W76_RS00865	COG3647	Membrane
J5W76_RS00870	COG0372	Belongs to the citrate synthase family
J5W76_RS00875	COG1214	PFAM Peptidase M22, glycoprotease
J5W76_RS00925	COG1979	alcohol dehydrogenase
J5W76_RS00930	COG2373	Large extracellular alpha-helical protein
J5W76_RS00935	COG0697	spore germination
J5W76_RS00950	COG1074	ATP-dependent DNA helicase activity
J5W76_RS00995	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J5W76_RS01000	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5W76_RS01010	COG0556	nucleotide-excision repair
J5W76_RS01045	COG0738	Major facilitator superfamily
J5W76_RS01050	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W76_RS01060	COG0561	phosphatase activity
J5W76_RS01105	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J5W76_RS01125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5W76_RS01130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5W76_RS01145	COG0159	tryptophan synthase activity
J5W76_RS01155	COG0135	phosphoribosylanthranilate isomerase activity
J5W76_RS01160	COG0134	indole-3-glycerol-phosphate synthase activity
J5W76_RS01165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5W76_RS01170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W76_RS01180	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J5W76_RS01185	COG0667	Aldo Keto reductase
J5W76_RS01220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5W76_RS01270	COG2885	chlorophyll binding
J5W76_RS01290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W76_RS01305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J5W76_RS01320	COG0203	ribosomal protein L17
J5W76_RS01325	COG0202	RNA polymerase activity
J5W76_RS01345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W76_RS01345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W76_RS01350	COG0726	polysaccharide deacetylase
J5W76_RS01375	COG0710	3-dehydroquinate dehydratase activity
J5W76_RS01395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W76_RS01400	COG3273	potassium ion transport
J5W76_RS01400	COG0471	metal ion transport
J5W76_RS01410	COG1561	YicC-like family, N-terminal region
J5W76_RS01415	COG3977	Valine--pyruvate aminotransferase
J5W76_RS01430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W76_RS01435	COG0428	transporter
J5W76_RS01440	COG3152	Membrane
J5W76_RS01445	COG0205	6-phosphofructokinase activity
J5W76_RS01450	COG1686	Belongs to the peptidase S11 family
J5W76_RS01465	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5W76_RS01480	COG0360	Binds together with S18 to 16S ribosomal RNA
J5W76_RS01490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5W76_RS01495	COG0131	Imidazoleglycerol-phosphate dehydratase
J5W76_RS01505	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5W76_RS01510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5W76_RS01535	COG0277	FAD linked oxidase domain protein
J5W76_RS01555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J5W76_RS01560	COG0484	heat shock protein binding
J5W76_RS01565	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5W76_RS01570	COG1872	DUF167
J5W76_RS01575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J5W76_RS01610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W76_RS01630	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J5W76_RS01635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5W76_RS01660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5W76_RS01665	COG0765	amino acid transport
J5W76_RS01745	COG0564	pseudouridine synthase activity
J5W76_RS01750	COG0778	Nitroreductase
J5W76_RS01770	COG0039	L-malate dehydrogenase activity
J5W76_RS01775	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J5W76_RS01800	COG0254	rRNA binding
J5W76_RS01805	COG0037	tRNA processing
J5W76_RS01815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J5W76_RS01840	COG2271	Major facilitator Superfamily
J5W76_RS01855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5W76_RS01865	COG0126	phosphoglycerate kinase activity
J5W76_RS01875	COG0632	four-way junction helicase activity
J5W76_RS01920	COG0459	protein refolding
J5W76_RS01925	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5W76_RS01930	COG0443	Heat shock 70 kDa protein
J5W76_RS01935	COG0438	transferase activity, transferring glycosyl groups
J5W76_RS01955	COG0298	carbon dioxide binding
J5W76_RS01960	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J5W76_RS01965	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J5W76_RS01975	COG0124	histidyl-tRNA synthetase
J5W76_RS01980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5W76_RS02005	COG3209	COG3209 Rhs family protein
J5W76_RS02045	COG0156	8-amino-7-oxononanoate synthase activity
J5W76_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
J5W76_RS02065	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J5W76_RS02085	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J5W76_RS02095	COG1183	phosphatidylcholine synthase activity
J5W76_RS02100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5W76_RS02110	COG1131	(ABC) transporter
J5W76_RS02115	COG0842	Transport permease protein
J5W76_RS02120	COG0842	Transport permease protein
J5W76_RS02130	COG3468	outer membrane autotransporter barrel domain protein
J5W76_RS02140	COG0456	acetyltransferase
J5W76_RS02155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5W76_RS02160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5W76_RS02170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5W76_RS02180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J5W76_RS02185	COG4335	DNA alkylation repair
J5W76_RS02210	COG0733	neurotransmitter:sodium symporter activity
J5W76_RS02215	COG0450	alkyl hydroperoxide reductase
J5W76_RS02225	COG0668	transmembrane transport
J5W76_RS02230	COG0528	UMP kinase activity
J5W76_RS02235	COG0233	cytoplasmic translational termination
J5W76_RS02245	COG0612	Peptidase, M16
J5W76_RS02280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5W76_RS02295	COG0573	inorganic phosphate transmembrane transporter activity
J5W76_RS02300	COG0581	inorganic phosphate transmembrane transporter activity
J5W76_RS02305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5W76_RS02380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W76_RS02390	COG0826	peptidase U32
J5W76_RS02400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J5W76_RS02405	COG0187	DNA topoisomerase II activity
J5W76_RS02415	COG0545	Peptidyl-prolyl cis-trans isomerase
J5W76_RS02420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5W76_RS02430	COG1408	metallophosphoesterase
J5W76_RS02465	COG0492	ferredoxin-NADP+ reductase activity
J5W76_RS02465	COG3118	belongs to the thioredoxin family
J5W76_RS02470	COG1760	l-serine dehydratase
J5W76_RS02480	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5W76_RS02495	COG0259	pyridoxamine-phosphate oxidase activity
J5W76_RS02500	COG0676	glucose-6-phosphate 1-epimerase activity
J5W76_RS02520	COG0594	ribonuclease P activity
J5W76_RS02530	COG0706	membrane insertase activity
J5W76_RS02535	COG1234	tRNA 3'-trailer cleavage
J5W76_RS02540	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5W76_RS02550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5W76_RS02560	COG0848	biopolymer transport protein
J5W76_RS02565	COG0811	peptide transport
J5W76_RS02575	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5W76_RS02585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5W76_RS02590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5W76_RS02595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5W76_RS02600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5W76_RS02600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5W76_RS02605	COG2003	Belongs to the UPF0758 family
J5W76_RS02625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J5W76_RS02630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J5W76_RS02650	COG0284	orotidine-5'-phosphate decarboxylase activity
J5W76_RS02710	COG0662	Cupin 2, conserved barrel domain protein
J5W76_RS02710	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5W76_RS02720	COG0416	fatty acid biosynthetic process
J5W76_RS02725	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J5W76_RS02735	COG0537	adenosine 5'-monophosphoramidase activity
J5W76_RS02740	COG0009	L-threonylcarbamoyladenylate synthase
J5W76_RS02745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5W76_RS02750	COG0228	four-way junction DNA binding
J5W76_RS02770	COG1862	Preprotein translocase
J5W76_RS02775	COG0343	queuine tRNA-ribosyltransferase activity
J5W76_RS02780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5W76_RS02790	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J5W76_RS02795	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J5W76_RS02800	COG0776	regulation of translation
J5W76_RS02835	COG0811	peptide transport
J5W76_RS02850	COG3250	beta-galactosidase activity
J5W76_RS02855	COG0525	valine-tRNA ligase activity
J5W76_RS02865	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5W76_RS02870	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5W76_RS02875	COG0255	Belongs to the universal ribosomal protein uL29 family
J5W76_RS02880	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J5W76_RS02885	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5W76_RS02890	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5W76_RS02900	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5W76_RS02905	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5W76_RS02910	COG0089	rRNA binding
J5W76_RS02915	COG0088	Forms part of the polypeptide exit tunnel
J5W76_RS02920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5W76_RS02925	COG0051	transcription antitermination factor activity, RNA binding
J5W76_RS02930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5W76_RS02935	COG0049	tRNA binding
J5W76_RS02940	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J5W76_RS02945	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J5W76_RS02955	COG3852	Histidine kinase
J5W76_RS02960	COG2204	response regulator
J5W76_RS02970	COG1722	exodeoxyribonuclease VII activity
J5W76_RS02975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5W76_RS02990	COG0795	lipopolysaccharide-transporting ATPase activity
J5W76_RS02995	COG1160	GTP binding
J5W76_RS03000	COG0444	Belongs to the ABC transporter superfamily
J5W76_RS03030	COG1136	(ABC) transporter
J5W76_RS03030	COG0577	efflux transmembrane transporter activity
J5W76_RS03035	COG4774	siderophore transport
J5W76_RS03085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5W76_RS03090	COG0799	negative regulation of ribosome biogenesis
J5W76_RS03095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5W76_RS03160	COG1136	(ABC) transporter
J5W76_RS03175	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5W76_RS03195	COG1077	Cell shape determining protein MreB Mrl
J5W76_RS03200	COG1530	ribonuclease E activity
J5W76_RS03230	COG0848	biopolymer transport protein
J5W76_RS03245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J5W76_RS03260	COG0134	indole-3-glycerol-phosphate synthase activity
J5W76_RS03265	COG2217	Heavy metal translocating P-type atpase
J5W76_RS03270	COG0792	nuclease activity
J5W76_RS03280	COG1253	flavin adenine dinucleotide binding
J5W76_RS03290	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5W76_RS03295	COG0137	argininosuccinate synthase activity
J5W76_RS03300	COG3119	arylsulfatase activity
J5W76_RS03310	COG0149	triose-phosphate isomerase activity
J5W76_RS03350	COG1040	competence protein
J5W76_RS03360	COG3956	TIGRFAM MazG family protein
J5W76_RS03400	COG1663	tetraacyldisaccharide 4'-kinase activity
J5W76_RS03405	COG0612	Peptidase, M16
J5W76_RS03435	COG0673	inositol 2-dehydrogenase activity
J5W76_RS03440	COG3034	peptidoglycan biosynthetic process
J5W76_RS03460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5W76_RS03465	COG0424	maF-like protein
J5W76_RS03470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5W76_RS03490	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J5W76_RS03500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5W76_RS03510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J5W76_RS03520	COG0571	ribonuclease III activity
J5W76_RS03535	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5W76_RS03550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5W76_RS03555	COG0470	DNA polymerase III
J5W76_RS03580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W76_RS03595	COG2226	methyltransferase
J5W76_RS03620	COG2942	2-epimerase
J5W76_RS03730	COG0535	radical SAM domain protein
J5W76_RS03795	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W76_RS03800	COG2255	four-way junction helicase activity
J5W76_RS03805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5W76_RS03810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5W76_RS03815	COG1216	Glycosyl transferase, family 2
J5W76_RS03820	COG1215	transferase activity, transferring glycosyl groups
J5W76_RS03830	COG0438	transferase activity, transferring glycosyl groups
J5W76_RS03835	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5W76_RS03855	COG0482	sulfurtransferase activity
J5W76_RS03860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5W76_RS03875	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W76_RS03880	COG2001	Belongs to the MraZ family
J5W76_RS03895	COG0768	penicillin binding
J5W76_RS03900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5W76_RS03905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J5W76_RS03910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5W76_RS03915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5W76_RS03925	COG0772	Belongs to the SEDS family
J5W76_RS03930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5W76_RS03935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W76_RS03940	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W76_RS03950	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J5W76_RS03960	COG0860	N-Acetylmuramoyl-L-alanine amidase
J5W76_RS03965	COG0321	lipoyl(octanoyl) transferase activity
J5W76_RS03970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5W76_RS03975	COG0066	3-isopropylmalate dehydratase activity
J5W76_RS03985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W76_RS04010	COG4608	Belongs to the ABC transporter superfamily
J5W76_RS04020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5W76_RS04025	COG0052	Belongs to the universal ribosomal protein uS2 family
J5W76_RS04030	COG0534	Mate efflux family protein
J5W76_RS04050	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5W76_RS04065	COG1137	ATPase activity
J5W76_RS04075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W76_RS04105	COG0017	Asparaginyl-tRNA synthetase
J5W76_RS04125	COG3118	belongs to the thioredoxin family
J5W76_RS04175	COG0583	DNA-binding transcription factor activity
J5W76_RS04180	COG2855	membrane
J5W76_RS04185	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5W76_RS04195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5W76_RS04205	COG0602	queuosine metabolic process
J5W76_RS04210	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W76_RS04215	COG0217	transcriptional regulatory protein
J5W76_RS04235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J5W76_RS04240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5W76_RS04245	COG4651	solute:proton antiporter activity
J5W76_RS04245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W76_RS04255	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5W76_RS04260	COG4864	UPF0365 protein
J5W76_RS04270	COG2022	thiamine diphosphate biosynthetic process
J5W76_RS04300	COG0531	amino acid
J5W76_RS04305	COG0546	phosphoglycolate phosphatase activity
J5W76_RS04310	COG0628	permease
J5W76_RS04320	COG3250	beta-galactosidase activity
J5W76_RS04330	COG0191	fructose-bisphosphate aldolase activity
J5W76_RS04375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5W76_RS04385	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W76_RS04400	COG3209	COG3209 Rhs family protein
J5W76_RS04415	COG2096	Adenosyltransferase
J5W76_RS04425	COG2814	Major facilitator Superfamily
J5W76_RS04435	COG1690	Belongs to the RtcB family
J5W76_RS04475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5W76_RS04480	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W76_RS04480	COG3409	Peptidoglycan-binding domain 1 protein
J5W76_RS04485	COG0656	L-ascorbic acid biosynthetic process
J5W76_RS04525	COG0022	dehydrogenase e1 component
J5W76_RS04530	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W76_RS04575	COG0321	lipoyl(octanoyl) transferase activity
J5W76_RS04575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J5W76_RS04580	COG0497	DNA recombination
J5W76_RS04585	COG2217	Heavy metal translocating P-type atpase
J5W76_RS04595	COG2755	lipolytic protein G-D-S-L family
J5W76_RS04595	COG0657	acetylesterase activity
J5W76_RS04600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5W76_RS04610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5W76_RS04615	COG1970	mechanosensitive ion channel activity
J5W76_RS04620	COG1785	Belongs to the alkaline phosphatase family
J5W76_RS04630	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W76_RS04635	COG1363	Peptidase, m42
J5W76_RS04645	COG1592	Rubrerythrin
J5W76_RS04715	COG3345	alpha-galactosidase
J5W76_RS04740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J5W76_RS04745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W76_RS04755	COG3481	metal-dependent phosphohydrolase, HD sub domain
J5W76_RS04765	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J5W76_RS04770	COG0148	phosphopyruvate hydratase activity
J5W76_RS04810	COG0165	Argininosuccinate lyase
J5W76_RS04815	COG0659	secondary active sulfate transmembrane transporter activity
J5W76_RS04820	COG1733	regulation of RNA biosynthetic process
J5W76_RS04830	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5W76_RS04865	COG0542	response to heat
J5W76_RS04885	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5W76_RS04895	COG0745	RESPONSE REGULATOR receiver
J5W76_RS04900	COG2205	protein histidine kinase activity
J5W76_RS04930	COG3250	beta-galactosidase activity
J5W76_RS04940	COG0084	hydrolase, TatD family'
J5W76_RS04980	COG0592	DNA-directed DNA polymerase activity
J5W76_RS04990	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5W76_RS04995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W76_RS04995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W76_RS05005	COG0445	tRNA wobble uridine modification
J5W76_RS05015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W76_RS05020	COG0440	acetolactate synthase activity
J5W76_RS05025	COG1643	Atp-dependent helicase
J5W76_RS05035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W76_RS05050	COG0107	imidazoleglycerol-phosphate synthase activity
J5W76_RS05065	COG1733	regulation of RNA biosynthetic process
J5W76_RS05075	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5W76_RS05075	COG0674	pyruvate-flavodoxin oxidoreductase activity
J5W76_RS05075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J5W76_RS05075	COG1013	pyruvate-flavodoxin oxidoreductase activity
J5W76_RS05080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J5W76_RS05105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5W76_RS05110	COG1073	alpha beta
J5W76_RS05115	COG1073	alpha beta
J5W76_RS05130	COG0535	radical SAM domain protein
J5W76_RS05135	COG0535	radical SAM domain protein
J5W76_RS05140	COG2873	o-acetylhomoserine
J5W76_RS05165	COG0473	3-isopropylmalate dehydrogenase activity
J5W76_RS05180	COG2755	lipolytic protein G-D-S-L family
J5W76_RS05180	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W76_RS05185	COG1028	Short-chain dehydrogenase reductase Sdr
J5W76_RS05215	COG0477	Major facilitator Superfamily
J5W76_RS05225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5W76_RS05230	COG0588	phosphoglycerate mutase activity
J5W76_RS05275	COG0745	RESPONSE REGULATOR receiver
J5W76_RS05280	COG0490	domain, Protein
J5W76_RS05280	COG0471	metal ion transport
J5W76_RS05315	COG1216	Glycosyl transferase, family 2
J5W76_RS05320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W76_RS05330	COG1216	Glycosyl transferase, family 2
J5W76_RS05330	COG1442	glycosyl transferase family 8
J5W76_RS05345	COG1408	metallophosphoesterase
J5W76_RS05360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5W76_RS05365	COG0196	riboflavin kinase activity
J5W76_RS05370	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J5W76_RS05385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5W76_RS05400	COG0546	phosphoglycolate phosphatase activity
J5W76_RS05410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5W76_RS05410	COG0519	Catalyzes the synthesis of GMP from XMP
J5W76_RS05415	COG0516	GMP reductase activity
J5W76_RS05415	COG0517	IMP dehydrogenase activity
J5W76_RS05450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W76_RS05500	COG4499	WXG100 protein secretion system (Wss), protein YukC
J5W76_RS05500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5W76_RS05510	COG0557	exoribonuclease II activity
J5W76_RS05515	COG0826	peptidase U32
J5W76_RS05520	COG0285	dihydrofolate synthase activity
J5W76_RS05535	COG0673	inositol 2-dehydrogenase activity
J5W76_RS05540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W76_RS05545	COG0737	Belongs to the 5'-nucleotidase family
J5W76_RS05555	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J5W76_RS05560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5W76_RS05575	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5W76_RS05580	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J5W76_RS05585	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J5W76_RS05590	COG0200	Binds to the 23S rRNA
J5W76_RS05595	COG0201	protein transport
J5W76_RS05600	COG0563	adenylate kinase activity
J5W76_RS05605	COG0024	Methionine aminopeptidase
J5W76_RS05620	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5W76_RS05640	COG1442	glycosyl transferase family 8
J5W76_RS05645	COG1216	Glycosyl transferase, family 2
J5W76_RS05650	COG1216	Glycosyl transferase, family 2
J5W76_RS05655	COG1216	Glycosyl transferase, family 2
J5W76_RS05660	COG0693	protein deglycase activity
J5W76_RS05665	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W76_RS05670	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J5W76_RS05680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W76_RS05690	COG1966	Carbon starvation protein
J5W76_RS05700	COG3119	arylsulfatase activity
J5W76_RS05705	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5W76_RS05710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5W76_RS05715	COG0195	Participates in both transcription termination and antitermination
J5W76_RS05720	COG0708	Exodeoxyribonuclease III
J5W76_RS05725	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5W76_RS05730	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J5W76_RS05735	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
J5W76_RS05740	COG0348	domain, Protein
J5W76_RS05755	COG0842	Transport permease protein
J5W76_RS05755	COG1716	ATPase activity
J5W76_RS05755	COG1131	(ABC) transporter
J5W76_RS05775	COG0724	RNA recognition motif
J5W76_RS05780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W76_RS05805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5W76_RS05815	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J5W76_RS05820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5W76_RS05835	COG1490	D-aminoacyl-tRNA deacylase activity
J5W76_RS05840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J5W76_RS05845	COG1053	succinate dehydrogenase
J5W76_RS05875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W76_RS05880	COG1028	Short-chain dehydrogenase reductase Sdr
J5W76_RS05890	COG0488	(ABC) transporter
J5W76_RS05900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J5W76_RS05910	COG3119	arylsulfatase activity
J5W76_RS05930	COG0175	sulfate reduction
J5W76_RS05935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5W76_RS05955	COG2267	carboxylic ester hydrolase activity
J5W76_RS05960	COG2095	MarC family integral membrane protein
J5W76_RS05965	COG0456	acetyltransferase
J5W76_RS05995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W76_RS06000	COG0488	(ABC) transporter
J5W76_RS06010	COG0697	spore germination
J5W76_RS06020	COG0215	cysteine-tRNA ligase activity
J5W76_RS06030	COG3119	arylsulfatase activity
J5W76_RS06060	COG0481	GTPase activity
J5W76_RS06080	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5W76_RS06085	COG0085	RNA polymerase activity
J5W76_RS06090	COG0222	ribosome binding
J5W76_RS06095	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5W76_RS06100	COG0081	regulation of translation
J5W76_RS06105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J5W76_RS06110	COG0250	Participates in transcription elongation, termination and antitermination
J5W76_RS06125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5W76_RS06135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5W76_RS06140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J5W76_RS06145	COG0740	serine-type endopeptidase activity
J5W76_RS06150	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5W76_RS06165	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J5W76_RS06185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W76_RS06250	COG2226	methyltransferase
J5W76_RS06255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5W76_RS06260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J5W76_RS06270	COG3119	arylsulfatase activity
J5W76_RS06275	COG0514	ATP-dependent DNA helicase (RecQ)
J5W76_RS06290	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J5W76_RS06295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5W76_RS06330	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J5W76_RS06350	COG1858	cytochrome C peroxidase
J5W76_RS06355	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5W76_RS06360	COG0590	tRNA wobble adenosine to inosine editing
J5W76_RS06365	COG1940	carbohydrate kinase activity
J5W76_RS06370	COG2217	Heavy metal translocating P-type atpase
J5W76_RS06375	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W76_RS06380	COG0237	dephospho-CoA kinase activity
J5W76_RS06410	COG1363	Peptidase, m42
J5W76_RS06415	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J5W76_RS06425	COG0006	proline dipeptidase activity
J5W76_RS06430	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J5W76_RS06460	COG5002	protein histidine kinase activity
J5W76_RS06465	COG0745	RESPONSE REGULATOR receiver
J5W76_RS06470	COG0129	dihydroxy-acid dehydratase activity
J5W76_RS06500	COG1368	sulfuric ester hydrolase activity
J5W76_RS06520	COG1482	cell wall glycoprotein biosynthetic process
J5W76_RS06530	COG1757	Na H antiporter
J5W76_RS06535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W76_RS06540	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
J5W76_RS06545	COG0505	Belongs to the CarA family
J5W76_RS06550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W76_RS06560	COG0067	glutamate synthase
J5W76_RS06560	COG0069	glutamate synthase activity
J5W76_RS06560	COG0070	glutamate synthase
J5W76_RS06580	COG4106	trans-aconitate 2-methyltransferase activity
J5W76_RS06585	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W76_RS06600	COG0038	chloride channel
J5W76_RS06620	COG4221	oxidoreductase activity
J5W76_RS06640	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5W76_RS06650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5W76_RS06655	COG0047	phosphoribosylformylglycinamidine synthase activity
J5W76_RS06665	COG1363	Peptidase, m42
J5W76_RS06675	COG0753	catalase activity
J5W76_RS06685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5W76_RS06690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J5W76_RS06720	COG0517	IMP dehydrogenase activity
J5W76_RS06720	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J5W76_RS06725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J5W76_RS06775	COG0356	it plays a direct role in the translocation of protons across the membrane
J5W76_RS06785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J5W76_RS06795	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5W76_RS06800	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5W76_RS06805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J5W76_RS06810	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5W76_RS06855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J5W76_RS06895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5W76_RS06920	COG0719	Fe-S assembly protein
J5W76_RS06925	COG0396	ATPase activity
J5W76_RS06930	COG0735	belongs to the Fur family
J5W76_RS06935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J5W76_RS06940	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5W76_RS06945	COG0802	atpase or kinase
J5W76_RS06950	COG1073	alpha beta
J5W76_RS06960	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W76_RS06970	COG2326	polyphosphate kinase activity
J5W76_RS06985	COG0742	ribosomal rna small subunit methyltransferase
J5W76_RS07005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W76_RS07020	COG1349	DNA-binding transcription factor activity
J5W76_RS07025	COG2326	polyphosphate kinase activity
J5W76_RS07045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W76_RS07075	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5W76_RS07115	COG3119	arylsulfatase activity
J5W76_RS07130	COG3119	arylsulfatase activity
J5W76_RS07140	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W76_RS07140	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W76_RS07155	COG0012	GTP binding
J5W76_RS07160	COG1686	Belongs to the peptidase S11 family
J5W76_RS07175	COG0758	DNA mediated transformation
J5W76_RS07190	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5W76_RS07195	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5W76_RS07200	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5W76_RS07205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J5W76_RS07225	COG0456	acetyltransferase
J5W76_RS07235	COG1058	Belongs to the CinA family
J5W76_RS07235	COG1546	Belongs to the CinA family
J5W76_RS07250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5W76_RS07255	COG0552	protein localization to endoplasmic reticulum
J5W76_RS07260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5W76_RS07265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J5W76_RS07270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W76_RS07270	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W76_RS07275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W76_RS07290	COG2814	Major facilitator Superfamily
J5W76_RS07305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5W76_RS07310	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5W76_RS07320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W76_RS07320	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W76_RS07325	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J5W76_RS07340	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W76_RS07365	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W76_RS07375	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5W76_RS07380	COG1136	(ABC) transporter
J5W76_RS07385	COG2234	aminopeptidase activity
J5W76_RS07400	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5W76_RS07415	COG4968	Prepilin-type N-terminal cleavage methylation domain
J5W76_RS07430	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5W76_RS07435	COG0101	tRNA pseudouridine synthase activity
J5W76_RS07460	COG0110	maltose O-acetyltransferase activity
J5W76_RS07465	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5W76_RS07470	COG1309	transcriptional regulator
J5W76_RS07490	COG1185	polyribonucleotide nucleotidyltransferase activity
J5W76_RS07495	COG2207	Transcriptional regulator
J5W76_RS07505	COG0697	spore germination
J5W76_RS07515	COG2814	Major facilitator Superfamily
J5W76_RS07520	COG2311	Membrane
J5W76_RS07530	COG1253	flavin adenine dinucleotide binding
J5W76_RS07535	COG1253	flavin adenine dinucleotide binding
J5W76_RS07560	COG0167	dihydroorotate dehydrogenase activity
J5W76_RS07575	COG0519	Catalyzes the synthesis of GMP from XMP
J5W76_RS07585	COG0076	glutamate decarboxylase activity
J5W76_RS07620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5W76_RS07625	COG0562	UDP-galactopyranose mutase
J5W76_RS07630	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5W76_RS07650	COG0534	Mate efflux family protein
J5W76_RS07655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W76_RS07680	COG1403	HNH endonuclease
J5W76_RS07720	COG0556	nucleotide-excision repair
J5W76_RS07845	COG0443	Heat shock 70 kDa protein
J5W76_RS07850	COG0443	Heat shock 70 kDa protein
J5W76_RS07855	COG0443	Heat shock 70 kDa protein
J5W76_RS07890	COG1373	ATPase (AAA superfamily
J5W76_RS07990	COG1131	(ABC) transporter
J5W76_RS08000	COG0714	Associated with various cellular activities
J5W76_RS08010	COG1881	PFAM PEBP family protein
J5W76_RS08040	COG1090	epimerase
J5W76_RS08050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5W76_RS08055	COG1119	ATPase activity
J5W76_RS08060	COG2186	Transcriptional regulator
J5W76_RS08095	COG0148	phosphopyruvate hydratase activity
J5W76_RS08110	COG0436	Aminotransferase
J5W76_RS08140	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5W76_RS08155	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J5W76_RS08175	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J5W76_RS08185	COG1199	ATP-dependent helicase activity
J5W76_RS08195	COG1122	ATPase activity
J5W76_RS08220	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5W76_RS08225	COG0598	Magnesium transport protein CorA
J5W76_RS08230	COG0359	binds to the 23S rRNA
J5W76_RS08235	COG0138	bifunctional purine biosynthesis protein purh
J5W76_RS08240	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5W76_RS08245	COG0736	holo-[acyl-carrier-protein] synthase activity
J5W76_RS08260	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
J5W76_RS08270	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W76_RS08270	COG3409	Peptidoglycan-binding domain 1 protein
J5W76_RS08275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5W76_RS08290	COG0437	4 iron, 4 sulfur cluster binding
J5W76_RS08315	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5W76_RS08355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W76_RS08360	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5W76_RS08365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5W76_RS08370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5W76_RS08390	COG1442	glycosyl transferase family 8
J5W76_RS08435	COG0539	negative regulation of cytoplasmic translation
J5W76_RS08450	COG0336	Belongs to the RNA methyltransferase TrmD family
J5W76_RS08460	COG1187	pseudouridine synthase activity
J5W76_RS08470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5W76_RS08480	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W76_RS08485	COG1393	Belongs to the ArsC family
J5W76_RS08490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5W76_RS08500	COG1063	alcohol dehydrogenase
J5W76_RS08505	COG0242	peptide deformylase activity
J5W76_RS08515	COG1028	Short-chain dehydrogenase reductase Sdr
J5W76_RS08605	COG0351	phosphomethylpyrimidine kinase
J5W76_RS08615	COG0471	metal ion transport
J5W76_RS08645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J5W76_RS08660	COG0028	Belongs to the TPP enzyme family
J5W76_RS08665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W76_RS08675	COG0205	6-phosphofructokinase activity
J5W76_RS08685	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J5W76_RS08695	COG0427	acetyl-CoA hydrolase
J5W76_RS08705	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J5W76_RS08725	COG0346	lactoylglutathione lyase activity
J5W76_RS08735	COG0335	large ribosomal subunit rRNA binding
J5W76_RS08755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J5W76_RS08775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5W76_RS08780	COG2755	lipolytic protein G-D-S-L family
J5W76_RS08780	COG0657	acetylesterase activity
J5W76_RS08785	COG2234	aminopeptidase activity
J5W76_RS08835	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5W76_RS08845	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W76_RS08850	COG0546	phosphoglycolate phosphatase activity
J5W76_RS08855	COG1322	Protein conserved in bacteria
J5W76_RS08865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W76_RS08870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W76_RS08890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5W76_RS08895	COG0504	CTP synthase activity
J5W76_RS08900	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5W76_RS08960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5W76_RS08965	COG1127	ABC transporter
J5W76_RS08980	COG1132	(ABC) transporter
J5W76_RS08985	COG1132	(ABC) transporter
J5W76_RS08990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5W76_RS09005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J5W76_RS09050	COG0601	transmembrane transport
J5W76_RS09055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5W76_RS09070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5W76_RS09105	COG1475	DNA binding
J5W76_RS09160	COG1918	ferrous iron import across plasma membrane
J5W76_RS09160	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J5W76_RS09170	COG3119	arylsulfatase activity
J5W76_RS09180	COG0750	zinc metalloprotease
J5W76_RS09200	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J5W76_RS09245	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J5W76_RS09250	COG0540	Belongs to the ATCase OTCase family
J5W76_RS09255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J5W76_RS09260	COG1720	tRNA m6t6A37 methyltransferase activity
J5W76_RS09275	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J5W76_RS09330	COG1538	Outer membrane efflux protein
J5W76_RS09335	COG0577	efflux transmembrane transporter activity
J5W76_RS09335	COG1136	(ABC) transporter
J5W76_RS09340	COG0577	efflux transmembrane transporter activity
J5W76_RS09340	COG1136	(ABC) transporter
J5W76_RS09360	COG0494	nUDIX hydrolase
J5W76_RS09370	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J5W76_RS09370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J5W76_RS09375	COG1940	carbohydrate kinase activity
J5W76_RS09385	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J5W76_RS09390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J5W76_RS09395	COG1469	GTP cyclohydrolase I activity
J5W76_RS09405	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J5W76_RS09410	COG0181	hydroxymethylbilane synthase activity
J5W76_RS09415	COG3189	MarR family transcriptional regulator
J5W76_RS09430	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5W76_RS09490	COG0515	serine threonine protein kinase
J5W76_RS09490	COG2815	serine threonine protein kinase
J5W76_RS09510	COG0156	8-amino-7-oxononanoate synthase activity
J5W76_RS09520	COG2816	NAD+ diphosphatase activity
J5W76_RS09525	COG0738	Major facilitator superfamily
J5W76_RS09530	COG0246	Mannitol dehydrogenase
J5W76_RS09535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5W76_RS09550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J5W76_RS09555	COG1692	metallophosphoesterase
J5W76_RS09565	COG0180	Tryptophanyl-tRNA synthetase
J5W76_RS09580	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5W76_RS09595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W76_RS09615	COG0542	response to heat
J5W76_RS09620	COG3869	Catalyzes the specific phosphorylation of arginine residues in
J5W76_RS09625	COG3880	PFAM UvrB UvrC protein
J5W76_RS09630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5W76_RS09635	COG1121	(ABC) transporter
J5W76_RS09660	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W76_RS09665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5W76_RS09675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W76_RS09685	COG1216	Glycosyl transferase, family 2
J5W76_RS09700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W76_RS09705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J5W76_RS09720	COG0489	protein tyrosine kinase activity
J5W76_RS09720	COG3206	protein involved in exopolysaccharide biosynthesis
J5W76_RS09725	COG0438	transferase activity, transferring glycosyl groups
J5W76_RS09730	COG0438	transferase activity, transferring glycosyl groups
J5W76_RS09735	COG1216	Glycosyl transferase, family 2
J5W76_RS09760	COG0438	transferase activity, transferring glycosyl groups
J5W76_RS09765	COG1216	Glycosyl transferase, family 2
J5W76_RS09765	COG1442	glycosyl transferase family 8
J5W76_RS09770	COG0438	transferase activity, transferring glycosyl groups
J5W76_RS09775	COG1216	Glycosyl transferase, family 2
J5W76_RS09775	COG1442	glycosyl transferase family 8
J5W76_RS09780	COG0438	transferase activity, transferring glycosyl groups
J5W76_RS09785	COG1216	Glycosyl transferase, family 2
J5W76_RS09815	COG0534	Mate efflux family protein
J5W76_RS09820	COG2226	methyltransferase
J5W76_RS09835	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5W76_RS09840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J5W76_RS09845	COG2890	protein-(glutamine-N5) methyltransferase activity
J5W76_RS09850	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5W76_RS09865	COG1115	amino acid carrier protein
J5W76_RS09875	COG2066	Belongs to the glutaminase family
J5W76_RS09880	COG0531	amino acid
J5W76_RS09885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5W76_RS09900	COG0038	chloride channel
J5W76_RS09915	COG4112	unkown
J5W76_RS09925	COG1538	Outer membrane efflux protein
J5W76_RS09935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W76_RS09940	COG0339	signal peptide processing
J5W76_RS09945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W76_RS09995	COG0489	protein tyrosine kinase activity
J5W76_RS10000	COG0534	Mate efflux family protein
J5W76_RS10010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5W76_RS10015	COG1312	Catalyzes the dehydration of D-mannonate
J5W76_RS10020	COG1904	glucuronate isomerase
J5W76_RS10025	COG0800	Aldolase
J5W76_RS10040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5W76_RS10045	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J5W76_RS10075	COG1070	Carbohydrate kinase
J5W76_RS10090	COG0738	Major facilitator superfamily
J5W76_RS10140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W76_RS10145	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5W76_RS10150	COG2132	Multicopper oxidase
J5W76_RS10180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W76_RS10185	COG4608	Belongs to the ABC transporter superfamily
J5W76_RS10190	COG0444	Belongs to the ABC transporter superfamily
J5W76_RS10195	COG4166	transmembrane transport
J5W76_RS10200	COG4239	(ABC) transporter, permease
J5W76_RS10205	COG0601	transmembrane transport
J5W76_RS10220	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J5W76_RS10225	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J5W76_RS10465	COG2304	oxidoreductase activity
J5W76_RS10480	COG0714	Associated with various cellular activities
J5W76_RS10485	COG0154	amidase activity
J5W76_RS10490	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W76_RS10525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W76_RS10530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W76_RS10565	COG1294	oxidase, subunit
J5W76_RS10570	COG1271	oxidase subunit
J5W76_RS10580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W76_RS10610	COG1528	Iron-storage protein
J5W76_RS10645	COG2949	membrane
J5W76_RS10650	COG1051	belongs to the nudix hydrolase family
J5W76_RS10660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W76_RS10670	COG0489	protein tyrosine kinase activity
J5W76_RS10735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W76_RS10735	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W76_RS10760	COG0514	ATP-dependent DNA helicase (RecQ)
J5W76_RS10780	COG2249	NAD(P)H dehydrogenase (quinone) activity
J5W76_RS10795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J5W76_RS10800	COG0045	succinate-CoA ligase (ADP-forming) activity
J5W76_RS10805	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5W76_RS10835	COG1570	exodeoxyribonuclease VII activity
J5W76_RS10865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W76_RS10870	COG2205	protein histidine kinase activity
J5W76_RS10885	COG0113	porphobilinogen synthase activity
J5W76_RS10895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J5W76_RS10910	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W76_RS10910	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W76_RS10940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W76_RS10945	COG0778	Nitroreductase
J5W76_RS10955	COG1335	isochorismatase
J5W76_RS10985	COG0375	protein maturation
J5W76_RS10990	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J5W76_RS11000	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J5W76_RS11030	COG2195	Cleaves the N-terminal amino acid of tripeptides
J5W76_RS11040	COG0280	phosphate acetyltransferase
J5W76_RS11040	COG0281	malic enzyme
J5W76_RS11050	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J5W76_RS11060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W76_RS11090	COG1216	Glycosyl transferase, family 2
J5W76_RS11095	COG1215	transferase activity, transferring glycosyl groups
J5W76_RS11105	COG0463	Glycosyl transferase, family 2
J5W76_RS11110	COG0110	maltose O-acetyltransferase activity
J5W76_RS11120	COG0438	transferase activity, transferring glycosyl groups
J5W76_RS11150	COG1442	glycosyl transferase family 8
J5W76_RS11150	COG1216	Glycosyl transferase, family 2
J5W76_RS11155	COG1216	Glycosyl transferase, family 2
J5W76_RS11160	COG4464	protein tyrosine phosphatase activity
J5W76_RS11175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W76_RS11190	COG1592	Rubrerythrin
J5W76_RS11195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5W76_RS11225	COG0753	catalase activity
J5W76_RS11240	COG1012	belongs to the aldehyde dehydrogenase family
J5W76_RS11245	COG3738	Protein conserved in bacteria
J5W76_RS11250	COG0151	Belongs to the GarS family
J5W76_RS11295	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J5W76_RS11300	COG0352	thiamine-phosphate diphosphorylase activity
J5W76_RS11315	COG1959	2 iron, 2 sulfur cluster binding
J5W76_RS11320	COG0629	single-stranded DNA binding
J5W76_RS11330	COG0811	peptide transport
J5W76_RS11340	COG0242	peptide deformylase activity
J5W76_RS11350	COG0640	Transcriptional regulator
J5W76_RS11425	COG0538	isocitrate dehydrogenase activity
J5W76_RS11445	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W76_RS11450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J5W76_RS11455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5W76_RS11460	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5W76_RS11465	COG0668	transmembrane transport
J5W76_RS11470	COG0724	RNA recognition motif
J5W76_RS11475	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
J5W76_RS11475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W76_RS11480	COG0805	protein transport
J5W76_RS11485	COG1968	undecaprenyl-diphosphatase activity
J5W76_RS11500	COG0745	RESPONSE REGULATOR receiver
J5W76_RS11505	COG5002	protein histidine kinase activity
J5W76_RS11575	COG1408	metallophosphoesterase
J5W76_RS11585	COG1090	epimerase
J5W76_RS11605	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5W76_RS11615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5W76_RS11625	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5W76_RS11635	COG1454	alcohol dehydrogenase
J5W76_RS11645	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J5W76_RS11645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5W76_RS11650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5W76_RS11660	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J5W76_RS11705	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J5W76_RS11705	COG0037	tRNA processing
J5W76_RS11715	COG0527	aspartate kinase activity
J5W76_RS11735	COG1741	Belongs to the pirin family
J5W76_RS11745	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J5W76_RS11765	COG0363	glucosamine-6-phosphate deaminase activity
J5W76_RS11770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W76_RS11775	COG1837	Belongs to the UPF0109 family
J5W76_RS11790	COG1091	dTDP-4-dehydrorhamnose reductase activity
J5W76_RS11810	COG0534	Mate efflux family protein
J5W76_RS11830	COG0789	Transcriptional regulator
J5W76_RS11855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W76_RS11860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W76_RS11865	COG0789	Transcriptional regulator
J5W76_RS11870	COG1408	metallophosphoesterase
J5W76_RS11875	COG0656	L-ascorbic acid biosynthetic process
J5W76_RS11885	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W76_RS11895	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J5W76_RS11935	COG0646	methionine synthase
J5W76_RS11935	COG1410	methionine synthase
J5W76_RS11940	COG2966	Psort location CytoplasmicMembrane, score
J5W76_RS11945	COG3610	response to peptide
J5W76_RS11950	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J5W76_RS11955	COG0732	type I restriction modification DNA specificity domain
J5W76_RS11960	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J5W76_RS11990	COG1703	isobutyryl-CoA mutase activity
J5W76_RS12015	COG0513	Belongs to the DEAD box helicase family
J5W76_RS12050	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5W76_RS12055	COG0513	Belongs to the DEAD box helicase family
J5W76_RS12060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5W76_RS12065	COG0418	dihydroorotase activity
J5W76_RS12080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W76_RS12125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5W76_RS12160	COG0714	Associated with various cellular activities
J5W76_RS12165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5W76_RS12170	COG1194	a g-specific adenine glycosylase
J5W76_RS12175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5W76_RS12185	COG0574	Belongs to the PEP-utilizing enzyme family
J5W76_RS12185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W76_RS12190	COG0166	Belongs to the GPI family
J5W76_RS12200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W76_RS12215	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W76_RS12215	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W76_RS12255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J5W76_RS12270	COG0515	serine threonine protein kinase
J5W76_RS12270	COG2815	serine threonine protein kinase
J5W76_RS12280	COG3033	Beta-eliminating lyase
J5W76_RS12295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W76_RS12295	COG0072	phenylalanine-tRNA ligase activity
J5W76_RS12310	COG3059	membrane
J5W76_RS12320	COG0326	Molecular chaperone. Has ATPase activity
J5W76_RS12325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W76_RS12350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W76_RS12355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5W76_RS12355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5W76_RS12375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J5W76_RS12380	COG1472	Belongs to the glycosyl hydrolase 3 family
J5W76_RS12385	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5W76_RS12400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5W76_RS12425	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5W76_RS12430	COG1063	alcohol dehydrogenase
J5W76_RS12450	COG0714	Associated with various cellular activities
J5W76_RS12460	COG0193	aminoacyl-tRNA hydrolase activity
J5W76_RS12465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5W76_RS12480	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5W76_RS12505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W76_RS12520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W76_RS12525	COG0512	Glutamine amidotransferase of anthranilate synthase
J5W76_RS12565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5W76_RS12570	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W76_RS12575	COG0586	Pfam SNARE associated Golgi protein
J5W76_RS12645	COG1518	maintenance of DNA repeat elements
J5W76_RS12670	COG0423	glycine-tRNA ligase activity
J5W76_RS12685	COG0436	Aminotransferase
J5W76_RS12690	COG1522	sequence-specific DNA binding
J5W76_RS12695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W76_RS12700	COG2967	ApaG domain
J5W76_RS12710	COG1215	transferase activity, transferring glycosyl groups
J5W76_RS12720	COG1678	Uncharacterized ACR, COG1678
J5W76_RS12725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5W76_RS12740	COG1131	(ABC) transporter
J5W76_RS12745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5W76_RS12750	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J5W76_RS12755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5W76_RS12760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W76_RS12770	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5W76_RS12785	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J5W76_RS12815	COG4106	trans-aconitate 2-methyltransferase activity
J5W76_RS12830	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5W76_RS12855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5W76_RS12860	COG2311	Membrane
J5W76_RS12890	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W76_RS12895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J5W76_RS12900	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5W76_RS12915	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W76_RS12920	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W76_RS12955	COG0673	inositol 2-dehydrogenase activity
J5W76_RS12960	COG0339	signal peptide processing
J5W76_RS12970	COG0018	arginyl-trna synthetase
J5W76_RS13015	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5W76_RS13045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W76_RS13060	COG0653	protein targeting
J5W76_RS13065	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J5W76_RS13065	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5W76_RS13075	COG0494	nUDIX hydrolase
J5W76_RS13080	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J5W76_RS13120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J5W76_RS13120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5W76_RS13130	COG2860	membrane
J5W76_RS13135	COG0275	rRNA processing
J5W76_RS13165	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J5W76_RS13205	COG3468	outer membrane autotransporter barrel domain protein