locus-tag	class	description
DMI77_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMI77_RS00010	COG1131	(ABC) transporter
DMI77_RS00030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DMI77_RS00035	COG0564	pseudouridine synthase activity
DMI77_RS00060	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DMI77_RS00065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMI77_RS00075	COG0513	Belongs to the DEAD box helicase family
DMI77_RS00085	COG0673	inositol 2-dehydrogenase activity
DMI77_RS00110	COG2814	Major facilitator Superfamily
DMI77_RS00115	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DMI77_RS00125	COG1971	Probably functions as a manganese efflux pump
DMI77_RS00150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI77_RS00175	COG0442	prolyl-tRNA aminoacylation
DMI77_RS00220	COG0531	amino acid
DMI77_RS00225	COG2066	Belongs to the glutaminase family
DMI77_RS00235	COG1115	amino acid carrier protein
DMI77_RS00245	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMI77_RS00250	COG2890	protein-(glutamine-N5) methyltransferase activity
DMI77_RS00255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DMI77_RS00260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DMI77_RS00280	COG2226	methyltransferase
DMI77_RS00285	COG0534	Mate efflux family protein
DMI77_RS00300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI77_RS00305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DMI77_RS00310	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI77_RS00330	COG1121	(ABC) transporter
DMI77_RS00335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DMI77_RS00340	COG3880	PFAM UvrB UvrC protein
DMI77_RS00345	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DMI77_RS00350	COG0542	response to heat
DMI77_RS00360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DMI77_RS00365	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMI77_RS00370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI77_RS00385	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMI77_RS00385	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DMI77_RS00395	COG0180	Tryptophanyl-tRNA synthetase
DMI77_RS00405	COG1692	metallophosphoesterase
DMI77_RS00415	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DMI77_RS00430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMI77_RS00435	COG0246	Mannitol dehydrogenase
DMI77_RS00440	COG0738	Major facilitator superfamily
DMI77_RS00460	COG0156	8-amino-7-oxononanoate synthase activity
DMI77_RS00470	COG1192	Involved in chromosome partitioning
DMI77_RS00475	COG0515	serine threonine protein kinase
DMI77_RS00475	COG3266	domain, Protein
DMI77_RS00515	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DMI77_RS00525	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMI77_RS00535	COG3189	MarR family transcriptional regulator
DMI77_RS00545	COG0181	hydroxymethylbilane synthase activity
DMI77_RS00550	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DMI77_RS00560	COG1469	GTP cyclohydrolase I activity
DMI77_RS00565	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DMI77_RS00570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DMI77_RS00575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DMI77_RS00580	COG1940	carbohydrate kinase activity
DMI77_RS00595	COG0494	nUDIX hydrolase
DMI77_RS00610	COG0577	efflux transmembrane transporter activity
DMI77_RS00610	COG1136	(ABC) transporter
DMI77_RS00615	COG0577	efflux transmembrane transporter activity
DMI77_RS00615	COG1136	(ABC) transporter
DMI77_RS00620	COG1538	Outer membrane efflux protein
DMI77_RS00625	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DMI77_RS00665	COG1720	tRNA m6t6A37 methyltransferase activity
DMI77_RS00670	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMI77_RS00675	COG0540	Belongs to the ATCase OTCase family
DMI77_RS00680	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DMI77_RS00730	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DMI77_RS00735	COG2957	Belongs to the agmatine deiminase family
DMI77_RS00935	COG0750	zinc metalloprotease
DMI77_RS00945	COG3119	arylsulfatase activity
DMI77_RS00955	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DMI77_RS00955	COG1918	ferrous iron import across plasma membrane
DMI77_RS00995	COG1475	DNA binding
DMI77_RS01030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DMI77_RS01045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMI77_RS01050	COG0601	transmembrane transport
DMI77_RS01100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DMI77_RS01115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMI77_RS01120	COG1132	(ABC) transporter
DMI77_RS01125	COG1132	(ABC) transporter
DMI77_RS01140	COG1127	ABC transporter
DMI77_RS01145	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DMI77_RS01175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DMI77_RS01195	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DMI77_RS01200	COG0504	CTP synthase activity
DMI77_RS01205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMI77_RS01235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI77_RS01245	COG1322	Protein conserved in bacteria
DMI77_RS01250	COG0546	phosphoglycolate phosphatase activity
DMI77_RS01255	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI77_RS01265	COG4591	ABC-type transport system involved in lipoprotein release permease component
DMI77_RS01265	COG4591	ABC-type transport system involved in lipoprotein release permease component
DMI77_RS01290	COG2234	aminopeptidase activity
DMI77_RS01295	COG0657	acetylesterase activity
DMI77_RS01295	COG2755	lipolytic protein G-D-S-L family
DMI77_RS01300	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DMI77_RS01320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DMI77_RS01355	COG0335	large ribosomal subunit rRNA binding
DMI77_RS01365	COG0346	lactoylglutathione lyase activity
DMI77_RS01380	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DMI77_RS01385	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DMI77_RS01395	COG0427	acetyl-CoA hydrolase
DMI77_RS01405	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DMI77_RS01415	COG0205	6-phosphofructokinase activity
DMI77_RS01430	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMI77_RS01435	COG0028	Belongs to the TPP enzyme family
DMI77_RS01450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DMI77_RS01465	COG0471	metal ion transport
DMI77_RS01475	COG0351	phosphomethylpyrimidine kinase
DMI77_RS01555	COG1028	Short-chain dehydrogenase reductase Sdr
DMI77_RS01565	COG0242	peptide deformylase activity
DMI77_RS01570	COG1063	alcohol dehydrogenase
DMI77_RS01580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMI77_RS01585	COG1393	Belongs to the ArsC family
DMI77_RS01590	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI77_RS01605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMI77_RS01620	COG1187	pseudouridine synthase activity
DMI77_RS01630	COG0336	Belongs to the RNA methyltransferase TrmD family
DMI77_RS01645	COG0539	negative regulation of cytoplasmic translation
DMI77_RS01700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DMI77_RS01705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DMI77_RS01710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DMI77_RS01750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMI77_RS01770	COG0662	Cupin 2, conserved barrel domain protein
DMI77_RS01770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DMI77_RS01780	COG0416	fatty acid biosynthetic process
DMI77_RS01785	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DMI77_RS01795	COG0537	adenosine 5'-monophosphoramidase activity
DMI77_RS01800	COG0009	L-threonylcarbamoyladenylate synthase
DMI77_RS01805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DMI77_RS01810	COG0228	four-way junction DNA binding
DMI77_RS01835	COG0343	queuine tRNA-ribosyltransferase activity
DMI77_RS01840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DMI77_RS01850	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DMI77_RS01860	COG0776	regulation of translation
DMI77_RS01890	COG0811	peptide transport
DMI77_RS01905	COG3250	beta-galactosidase activity
DMI77_RS01910	COG0525	valine-tRNA ligase activity
DMI77_RS01920	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DMI77_RS01925	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DMI77_RS01930	COG0255	Belongs to the universal ribosomal protein uL29 family
DMI77_RS01935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DMI77_RS01940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DMI77_RS01945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DMI77_RS01955	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DMI77_RS01960	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DMI77_RS01965	COG0089	rRNA binding
DMI77_RS01970	COG0088	Forms part of the polypeptide exit tunnel
DMI77_RS01975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DMI77_RS01980	COG0051	transcription antitermination factor activity, RNA binding
DMI77_RS01985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMI77_RS01990	COG0049	tRNA binding
DMI77_RS01995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DMI77_RS02005	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DMI77_RS02015	COG3852	Histidine kinase
DMI77_RS02020	COG2204	response regulator
DMI77_RS02030	COG1722	exodeoxyribonuclease VII activity
DMI77_RS02035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMI77_RS02050	COG0795	lipopolysaccharide-transporting ATPase activity
DMI77_RS02055	COG1160	GTP binding
DMI77_RS02060	COG0444	Belongs to the ABC transporter superfamily
DMI77_RS02095	COG1136	(ABC) transporter
DMI77_RS02095	COG0577	efflux transmembrane transporter activity
DMI77_RS02150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DMI77_RS02155	COG0799	negative regulation of ribosome biogenesis
DMI77_RS02160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMI77_RS02215	COG1136	(ABC) transporter
DMI77_RS02230	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DMI77_RS02240	COG4221	oxidoreductase activity
DMI77_RS02260	COG0038	chloride channel
DMI77_RS02275	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI77_RS02305	COG0070	glutamate synthase
DMI77_RS02305	COG0067	glutamate synthase
DMI77_RS02305	COG0069	glutamate synthase activity
DMI77_RS02315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMI77_RS02320	COG0505	Belongs to the CarA family
DMI77_RS02325	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DMI77_RS02330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI77_RS02335	COG1757	Na H antiporter
DMI77_RS02345	COG1482	cell wall glycoprotein biosynthetic process
DMI77_RS02355	COG0076	glutamate decarboxylase activity
DMI77_RS02360	COG3468	outer membrane autotransporter barrel domain protein
DMI77_RS02375	COG0167	dihydroorotate dehydrogenase activity
DMI77_RS02380	COG0352	thiamine-phosphate diphosphorylase activity
DMI77_RS02400	COG1253	flavin adenine dinucleotide binding
DMI77_RS02405	COG1253	flavin adenine dinucleotide binding
DMI77_RS02415	COG1185	polyribonucleotide nucleotidyltransferase activity
DMI77_RS02435	COG1309	transcriptional regulator
DMI77_RS02440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DMI77_RS02470	COG0101	tRNA pseudouridine synthase activity
DMI77_RS02475	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DMI77_RS02495	COG4968	Prepilin-type N-terminal cleavage methylation domain
DMI77_RS02500	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DMI77_RS02510	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI77_RS02515	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DMI77_RS02535	COG2234	aminopeptidase activity
DMI77_RS02540	COG1136	(ABC) transporter
DMI77_RS02545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DMI77_RS02555	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI77_RS02580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI77_RS02590	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DMI77_RS02595	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DMI77_RS02605	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DMI77_RS02610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DMI77_RS02620	COG2814	Major facilitator Superfamily
DMI77_RS02630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI77_RS02635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMI77_RS02635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMI77_RS02640	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DMI77_RS02645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DMI77_RS02650	COG0552	protein localization to endoplasmic reticulum
DMI77_RS02655	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DMI77_RS02675	COG1546	Belongs to the CinA family
DMI77_RS02675	COG1058	Belongs to the CinA family
DMI77_RS02685	COG0456	acetyltransferase
DMI77_RS02710	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DMI77_RS02715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DMI77_RS02720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMI77_RS02725	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMI77_RS02740	COG0758	DNA mediated transformation
DMI77_RS02750	COG1686	Belongs to the peptidase S11 family
DMI77_RS02755	COG0012	GTP binding
DMI77_RS02760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DMI77_RS02770	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMI77_RS02770	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMI77_RS02785	COG3119	arylsulfatase activity
DMI77_RS02825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DMI77_RS02845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI77_RS02855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMI77_RS02875	COG2326	polyphosphate kinase activity
DMI77_RS02880	COG1349	DNA-binding transcription factor activity
DMI77_RS02900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMI77_RS02920	COG0742	ribosomal rna small subunit methyltransferase
DMI77_RS02935	COG2326	polyphosphate kinase activity
DMI77_RS02940	COG5434	Belongs to the glycosyl hydrolase 28 family
DMI77_RS02950	COG1073	alpha beta
DMI77_RS02955	COG0802	atpase or kinase
DMI77_RS02960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DMI77_RS02965	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DMI77_RS02970	COG0735	belongs to the Fur family
DMI77_RS02975	COG0396	ATPase activity
DMI77_RS02980	COG0719	Fe-S assembly protein
DMI77_RS03005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DMI77_RS03045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMI77_RS03090	COG3209	COG3209 Rhs family protein
DMI77_RS03120	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DMI77_RS03125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DMI77_RS03130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DMI77_RS03135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DMI77_RS03140	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMI77_RS03145	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DMI77_RS03155	COG0356	it plays a direct role in the translocation of protons across the membrane
DMI77_RS03215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DMI77_RS03240	COG1045	serine acetyltransferase
DMI77_RS03250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DMI77_RS03255	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DMI77_RS03265	COG0753	catalase activity
DMI77_RS03275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DMI77_RS03285	COG3119	arylsulfatase activity
DMI77_RS03310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DMI77_RS03320	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMI77_RS03325	COG0047	phosphoribosylformylglycinamidine synthase activity
DMI77_RS03335	COG1363	Peptidase, m42
DMI77_RS03350	COG1077	Cell shape determining protein MreB Mrl
DMI77_RS03355	COG1530	ribonuclease E activity
DMI77_RS03385	COG0848	biopolymer transport protein
DMI77_RS03400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DMI77_RS03415	COG0134	indole-3-glycerol-phosphate synthase activity
DMI77_RS03420	COG2217	Heavy metal translocating P-type atpase
DMI77_RS03425	COG0792	nuclease activity
DMI77_RS03435	COG1253	flavin adenine dinucleotide binding
DMI77_RS03445	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DMI77_RS03460	COG0137	argininosuccinate synthase activity
DMI77_RS03465	COG3119	arylsulfatase activity
DMI77_RS03475	COG0149	triose-phosphate isomerase activity
DMI77_RS03510	COG1040	competence protein
DMI77_RS03520	COG3956	TIGRFAM MazG family protein
DMI77_RS03550	COG1663	tetraacyldisaccharide 4'-kinase activity
DMI77_RS03555	COG0612	Peptidase, M16
DMI77_RS03595	COG0673	inositol 2-dehydrogenase activity
DMI77_RS03600	COG3034	peptidoglycan biosynthetic process
DMI77_RS03620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMI77_RS03625	COG0424	maF-like protein
DMI77_RS03635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DMI77_RS03640	COG0515	serine threonine protein kinase
DMI77_RS03640	COG2815	serine threonine protein kinase
DMI77_RS03655	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DMI77_RS03665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DMI77_RS03675	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DMI77_RS03685	COG0571	ribonuclease III activity
DMI77_RS03705	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DMI77_RS03720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DMI77_RS03725	COG0470	DNA polymerase III
DMI77_RS03745	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMI77_RS03875	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI77_RS03880	COG2255	four-way junction helicase activity
DMI77_RS03885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMI77_RS03890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMI77_RS03900	COG1215	transferase activity, transferring glycosyl groups
DMI77_RS03905	COG1215	transferase activity, transferring glycosyl groups
DMI77_RS03940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DMI77_RS03955	COG0482	sulfurtransferase activity
DMI77_RS03960	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DMI77_RS03980	COG2860	membrane
DMI77_RS03985	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DMI77_RS03990	COG2001	Belongs to the MraZ family
DMI77_RS03995	COG0275	rRNA processing
DMI77_RS04005	COG0768	penicillin binding
DMI77_RS04010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DMI77_RS04015	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DMI77_RS04020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMI77_RS04025	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DMI77_RS04035	COG0772	Belongs to the SEDS family
DMI77_RS04040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DMI77_RS04045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMI77_RS04050	COG1181	Belongs to the D-alanine--D-alanine ligase family
DMI77_RS04065	COG0860	N-Acetylmuramoyl-L-alanine amidase
DMI77_RS04070	COG0321	lipoyl(octanoyl) transferase activity
DMI77_RS04075	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMI77_RS04080	COG0066	3-isopropylmalate dehydratase activity
DMI77_RS04090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI77_RS04100	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMI77_RS04120	COG3209	COG3209 Rhs family protein
DMI77_RS04145	COG4608	Belongs to the ABC transporter superfamily
DMI77_RS04155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DMI77_RS04160	COG0052	Belongs to the universal ribosomal protein uS2 family
DMI77_RS04165	COG0534	Mate efflux family protein
DMI77_RS04175	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DMI77_RS04190	COG1137	ATPase activity
DMI77_RS04200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMI77_RS04230	COG0017	Asparaginyl-tRNA synthetase
DMI77_RS04240	COG3118	belongs to the thioredoxin family
DMI77_RS04300	COG0583	DNA-binding transcription factor activity
DMI77_RS04305	COG2855	membrane
DMI77_RS04310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DMI77_RS04325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMI77_RS04335	COG0602	queuosine metabolic process
DMI77_RS04340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMI77_RS04345	COG0217	transcriptional regulatory protein
DMI77_RS04355	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DMI77_RS04360	COG4106	trans-aconitate 2-methyltransferase activity
DMI77_RS04365	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMI77_RS04365	COG4651	solute:proton antiporter activity
DMI77_RS04380	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DMI77_RS04385	COG4864	UPF0365 protein
DMI77_RS04395	COG2022	thiamine diphosphate biosynthetic process
DMI77_RS04400	COG0531	amino acid
DMI77_RS04410	COG0628	permease
DMI77_RS04415	COG0019	diaminopimelate decarboxylase activity
DMI77_RS04425	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI77_RS04430	COG0191	fructose-bisphosphate aldolase activity
DMI77_RS04455	COG1217	gtp-binding protein TYPA
DMI77_RS04480	COG3152	Membrane
DMI77_RS04485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DMI77_RS04495	COG1181	Belongs to the D-alanine--D-alanine ligase family
DMI77_RS04525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMI77_RS04530	COG0517	IMP dehydrogenase activity
DMI77_RS04530	COG0516	GMP reductase activity
DMI77_RS04535	COG0519	Catalyzes the synthesis of GMP from XMP
DMI77_RS04535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMI77_RS04550	COG0546	phosphoglycolate phosphatase activity
DMI77_RS04565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DMI77_RS04580	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DMI77_RS04585	COG0196	riboflavin kinase activity
DMI77_RS04590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DMI77_RS04605	COG1408	metallophosphoesterase
DMI77_RS04620	COG1442	glycosyl transferase family 8
DMI77_RS04620	COG1216	Glycosyl transferase, family 2
DMI77_RS04630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI77_RS04635	COG1216	Glycosyl transferase, family 2
DMI77_RS04645	COG0297	glycogen (starch) synthase activity
DMI77_RS04655	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI77_RS04655	COG2755	lipolytic protein G-D-S-L family
DMI77_RS04675	COG0471	metal ion transport
DMI77_RS04675	COG0490	domain, Protein
DMI77_RS04715	COG0588	phosphoglycerate mutase activity
DMI77_RS04720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMI77_RS04735	COG0477	Major facilitator Superfamily
DMI77_RS04740	COG1607	acyl-coa hydrolase
DMI77_RS04765	COG1028	Short-chain dehydrogenase reductase Sdr
DMI77_RS04770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DMI77_RS04805	COG1475	DNA binding
DMI77_RS04810	COG3969	phosphoadenosine phosphosulfate
DMI77_RS04825	COG0473	3-isopropylmalate dehydrogenase activity
DMI77_RS04840	COG0606	chelatase, subunit chli
DMI77_RS04850	COG2873	o-acetylhomoserine
DMI77_RS04855	COG0535	radical SAM domain protein
DMI77_RS04860	COG0535	radical SAM domain protein
DMI77_RS04875	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMI77_RS04880	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DMI77_RS04890	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DMI77_RS04895	COG0674	pyruvate-flavodoxin oxidoreductase activity
DMI77_RS04895	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DMI77_RS04895	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DMI77_RS04895	COG1013	pyruvate-flavodoxin oxidoreductase activity
DMI77_RS04915	COG0107	imidazoleglycerol-phosphate synthase activity
DMI77_RS04930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMI77_RS04940	COG1643	Atp-dependent helicase
DMI77_RS04945	COG0440	acetolactate synthase activity
DMI77_RS04950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI77_RS04960	COG0445	tRNA wobble uridine modification
DMI77_RS04965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMI77_RS04965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMI77_RS04970	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DMI77_RS04980	COG0592	DNA-directed DNA polymerase activity
DMI77_RS05045	COG1388	LysM domain
DMI77_RS05045	COG0791	NLP P60 protein
DMI77_RS05050	COG0084	hydrolase, TatD family'
DMI77_RS05060	COG3250	beta-galactosidase activity
DMI77_RS05080	COG2205	protein histidine kinase activity
DMI77_RS05085	COG0745	RESPONSE REGULATOR receiver
DMI77_RS05095	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMI77_RS05105	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DMI77_RS05110	COG3345	alpha-galactosidase
DMI77_RS05115	COG0542	response to heat
DMI77_RS05160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DMI77_RS05175	COG1733	regulation of RNA biosynthetic process
DMI77_RS05180	COG0659	secondary active sulfate transmembrane transporter activity
DMI77_RS05185	COG0165	Argininosuccinate lyase
DMI77_RS05205	COG0148	phosphopyruvate hydratase activity
DMI77_RS05210	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DMI77_RS05235	COG3481	metal-dependent phosphohydrolase, HD sub domain
DMI77_RS05245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMI77_RS05250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMI77_RS05280	COG3345	alpha-galactosidase
DMI77_RS05320	COG1592	Rubrerythrin
DMI77_RS05330	COG1363	Peptidase, m42
DMI77_RS05335	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI77_RS05345	COG1785	Belongs to the alkaline phosphatase family
DMI77_RS05350	COG1970	mechanosensitive ion channel activity
DMI77_RS05355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMI77_RS05365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DMI77_RS05370	COG2755	lipolytic protein G-D-S-L family
DMI77_RS05370	COG0657	acetylesterase activity
DMI77_RS05380	COG2217	Heavy metal translocating P-type atpase
DMI77_RS05385	COG0497	DNA recombination
DMI77_RS05390	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DMI77_RS05390	COG0321	lipoyl(octanoyl) transferase activity
DMI77_RS05395	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DMI77_RS05425	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI77_RS05430	COG0022	dehydrogenase e1 component
DMI77_RS05440	COG4978	Transcriptional regulator
DMI77_RS05440	COG0789	Transcriptional regulator
DMI77_RS05445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI77_RS05450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMI77_RS05485	COG0656	L-ascorbic acid biosynthetic process
DMI77_RS05490	COG3409	Peptidoglycan-binding domain 1 protein
DMI77_RS05490	COG5632	N-Acetylmuramoyl-L-alanine amidase
DMI77_RS05495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DMI77_RS05530	COG1690	Belongs to the RtcB family
DMI77_RS05540	COG2814	Major facilitator Superfamily
DMI77_RS05545	COG2096	Adenosyltransferase
DMI77_RS05560	COG3209	COG3209 Rhs family protein
DMI77_RS05610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMI77_RS05620	COG0557	exoribonuclease II activity
DMI77_RS05625	COG0826	peptidase U32
DMI77_RS05630	COG0285	dihydrofolate synthase activity
DMI77_RS05645	COG0673	inositol 2-dehydrogenase activity
DMI77_RS05665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMI77_RS05670	COG0737	Belongs to the 5'-nucleotidase family
DMI77_RS05680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMI77_RS05685	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DMI77_RS05700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DMI77_RS05705	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DMI77_RS05710	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DMI77_RS05715	COG0200	Binds to the 23S rRNA
DMI77_RS05720	COG0201	protein transport
DMI77_RS05725	COG0563	adenylate kinase activity
DMI77_RS05730	COG0024	Methionine aminopeptidase
DMI77_RS05745	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DMI77_RS05760	COG1442	glycosyl transferase family 8
DMI77_RS05765	COG1442	glycosyl transferase family 8
DMI77_RS05770	COG1216	Glycosyl transferase, family 2
DMI77_RS05775	COG1216	Glycosyl transferase, family 2
DMI77_RS05780	COG1216	Glycosyl transferase, family 2
DMI77_RS05785	COG1216	Glycosyl transferase, family 2
DMI77_RS05790	COG0693	protein deglycase activity
DMI77_RS05795	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI77_RS05800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DMI77_RS05810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMI77_RS05820	COG1966	Carbon starvation protein
DMI77_RS05830	COG3119	arylsulfatase activity
DMI77_RS05835	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DMI77_RS05840	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DMI77_RS05845	COG0195	Participates in both transcription termination and antitermination
DMI77_RS05850	COG0708	Exodeoxyribonuclease III
DMI77_RS05855	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DMI77_RS05860	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DMI77_RS05865	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DMI77_RS05890	COG1716	ATPase activity
DMI77_RS05890	COG1131	(ABC) transporter
DMI77_RS05890	COG0842	Transport permease protein
DMI77_RS05910	COG0724	RNA recognition motif
DMI77_RS05915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI77_RS05940	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DMI77_RS05945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DMI77_RS05950	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DMI77_RS05955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMI77_RS05970	COG1490	D-aminoacyl-tRNA deacylase activity
DMI77_RS05975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMI77_RS05980	COG1053	succinate dehydrogenase
DMI77_RS06025	COG1028	Short-chain dehydrogenase reductase Sdr
DMI77_RS06035	COG0488	(ABC) transporter
DMI77_RS06045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DMI77_RS06065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMI77_RS06075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMI77_RS06080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DMI77_RS06135	COG2267	carboxylic ester hydrolase activity
DMI77_RS06140	COG2095	MarC family integral membrane protein
DMI77_RS06195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMI77_RS06200	COG0488	(ABC) transporter
DMI77_RS06210	COG0697	spore germination
DMI77_RS06220	COG0215	cysteine-tRNA ligase activity
DMI77_RS06225	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI77_RS06230	COG3119	arylsulfatase activity
DMI77_RS06245	COG0481	GTPase activity
DMI77_RS06265	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMI77_RS06270	COG0085	RNA polymerase activity
DMI77_RS06275	COG0222	ribosome binding
DMI77_RS06280	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DMI77_RS06285	COG0081	regulation of translation
DMI77_RS06290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DMI77_RS06295	COG0250	Participates in transcription elongation, termination and antitermination
DMI77_RS06310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMI77_RS06320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DMI77_RS06325	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DMI77_RS06330	COG0740	serine-type endopeptidase activity
DMI77_RS06335	COG0544	peptidyl-prolyl cis-trans isomerase activity
DMI77_RS06350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DMI77_RS06370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMI77_RS06430	COG2226	methyltransferase
DMI77_RS06435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DMI77_RS06440	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DMI77_RS06450	COG1902	pentaerythritol trinitrate reductase activity
DMI77_RS06450	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMI77_RS06460	COG3119	arylsulfatase activity
DMI77_RS06465	COG0514	ATP-dependent DNA helicase (RecQ)
DMI77_RS06485	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DMI77_RS06490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMI77_RS06505	COG2217	Heavy metal translocating P-type atpase
DMI77_RS06550	COG1858	cytochrome C peroxidase
DMI77_RS06555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DMI77_RS06560	COG0590	tRNA wobble adenosine to inosine editing
DMI77_RS06565	COG1940	carbohydrate kinase activity
DMI77_RS06570	COG2217	Heavy metal translocating P-type atpase
DMI77_RS06580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMI77_RS06585	COG0237	dephospho-CoA kinase activity
DMI77_RS06615	COG1363	Peptidase, m42
DMI77_RS06620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DMI77_RS06635	COG0006	proline dipeptidase activity
DMI77_RS06640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DMI77_RS06675	COG0745	RESPONSE REGULATOR receiver
DMI77_RS06680	COG0129	dihydroxy-acid dehydratase activity
DMI77_RS06710	COG1368	sulfuric ester hydrolase activity
DMI77_RS06750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DMI77_RS06755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DMI77_RS06780	COG0534	Mate efflux family protein
DMI77_RS06785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMI77_RS06860	COG1881	PFAM PEBP family protein
DMI77_RS06890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DMI77_RS06895	COG1119	ATPase activity
DMI77_RS06900	COG2186	Transcriptional regulator
DMI77_RS06930	COG0148	phosphopyruvate hydratase activity
DMI77_RS06945	COG0436	Aminotransferase
DMI77_RS06960	COG3345	alpha-galactosidase
DMI77_RS06970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DMI77_RS06985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DMI77_RS07005	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DMI77_RS07015	COG1199	ATP-dependent helicase activity
DMI77_RS07020	COG1122	ATPase activity
DMI77_RS07045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DMI77_RS07050	COG0598	Magnesium transport protein CorA
DMI77_RS07055	COG0359	binds to the 23S rRNA
DMI77_RS07060	COG0138	bifunctional purine biosynthesis protein purh
DMI77_RS07065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DMI77_RS07070	COG0736	holo-[acyl-carrier-protein] synthase activity
DMI77_RS07085	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DMI77_RS07090	COG5632	N-Acetylmuramoyl-L-alanine amidase
DMI77_RS07090	COG3409	Peptidoglycan-binding domain 1 protein
DMI77_RS07095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DMI77_RS07105	COG0437	4 iron, 4 sulfur cluster binding
DMI77_RS07130	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMI77_RS07175	COG0284	orotidine-5'-phosphate decarboxylase activity
DMI77_RS07190	COG3568	Endonuclease Exonuclease Phosphatase
DMI77_RS07195	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DMI77_RS07200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DMI77_RS07225	COG2003	Belongs to the UPF0758 family
DMI77_RS07230	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DMI77_RS07230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DMI77_RS07235	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DMI77_RS07240	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DMI77_RS07245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DMI77_RS07255	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DMI77_RS07260	COG0322	excinuclease ABC activity
DMI77_RS07265	COG0811	peptide transport
DMI77_RS07270	COG0848	biopolymer transport protein
DMI77_RS07280	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DMI77_RS07285	COG0483	inositol monophosphate 1-phosphatase activity
DMI77_RS07290	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMI77_RS07315	COG3266	domain, Protein
DMI77_RS07315	COG0515	serine threonine protein kinase
DMI77_RS07330	COG0631	protein serine/threonine phosphatase activity
DMI77_RS07335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI77_RS07340	COG0515	serine threonine protein kinase
DMI77_RS07340	COG2815	serine threonine protein kinase
DMI77_RS07355	COG0631	protein serine/threonine phosphatase activity
DMI77_RS07395	COG0706	membrane insertase activity
DMI77_RS07400	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DMI77_RS07410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DMI77_RS07425	COG0259	pyridoxamine-phosphate oxidase activity
DMI77_RS07440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DMI77_RS07450	COG1760	l-serine dehydratase
DMI77_RS07455	COG0492	ferredoxin-NADP+ reductase activity
DMI77_RS07455	COG3118	belongs to the thioredoxin family
DMI77_RS07535	COG1408	metallophosphoesterase
DMI77_RS07545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DMI77_RS07550	COG0545	Peptidyl-prolyl cis-trans isomerase
DMI77_RS07565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMI77_RS07575	COG0826	peptidase U32
DMI77_RS07580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DMI77_RS07610	COG0581	inorganic phosphate transmembrane transporter activity
DMI77_RS07615	COG0573	inorganic phosphate transmembrane transporter activity
DMI77_RS07630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DMI77_RS07640	COG2017	converts alpha-aldose to the beta-anomer
DMI77_RS07655	COG0612	Peptidase, M16
DMI77_RS07665	COG0233	cytoplasmic translational termination
DMI77_RS07670	COG0528	UMP kinase activity
DMI77_RS07675	COG0668	transmembrane transport
DMI77_RS07685	COG0450	alkyl hydroperoxide reductase
DMI77_RS07690	COG0733	neurotransmitter:sodium symporter activity
DMI77_RS07710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMI77_RS07720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMI77_RS07730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMI77_RS07735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMI77_RS07755	COG2169	Transcriptional regulator
DMI77_RS07760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMI77_RS07770	COG0842	Transport permease protein
DMI77_RS07775	COG0842	Transport permease protein
DMI77_RS07780	COG1131	(ABC) transporter
DMI77_RS07790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DMI77_RS07795	COG1183	phosphatidylcholine synthase activity
DMI77_RS07805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DMI77_RS07835	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DMI77_RS07840	COG1028	Short-chain dehydrogenase reductase Sdr
DMI77_RS07860	COG0156	8-amino-7-oxononanoate synthase activity
DMI77_RS07890	COG3209	COG3209 Rhs family protein
DMI77_RS07920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DMI77_RS07925	COG0124	histidyl-tRNA synthetase
DMI77_RS07935	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DMI77_RS07940	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DMI77_RS07945	COG0298	carbon dioxide binding
DMI77_RS07965	COG0438	transferase activity, transferring glycosyl groups
DMI77_RS07970	COG0443	Heat shock 70 kDa protein
DMI77_RS07975	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DMI77_RS07980	COG0459	protein refolding
DMI77_RS08025	COG0632	four-way junction helicase activity
DMI77_RS08035	COG0126	phosphoglycerate kinase activity
DMI77_RS08045	COG1082	Xylose isomerase domain protein TIM barrel
DMI77_RS08055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DMI77_RS08065	COG2271	Major facilitator Superfamily
DMI77_RS08070	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
DMI77_RS08080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DMI77_RS08090	COG0037	tRNA processing
DMI77_RS08095	COG0254	rRNA binding
DMI77_RS08140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DMI77_RS08145	COG0039	L-malate dehydrogenase activity
DMI77_RS08165	COG0778	Nitroreductase
DMI77_RS08170	COG0564	pseudouridine synthase activity
DMI77_RS08185	COG1335	isochorismatase
DMI77_RS08220	COG1126	abc transporter atp-binding protein
DMI77_RS08225	COG0765	amino acid transport
DMI77_RS08230	COG1216	Glycosyl transferase, family 2
DMI77_RS08245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI77_RS08250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMI77_RS08260	COG1596	polysaccharide export
DMI77_RS08265	COG0489	protein tyrosine kinase activity
DMI77_RS08265	COG3206	protein involved in exopolysaccharide biosynthesis
DMI77_RS08270	COG0438	transferase activity, transferring glycosyl groups
DMI77_RS08280	COG1215	transferase activity, transferring glycosyl groups
DMI77_RS08305	COG0438	transferase activity, transferring glycosyl groups
DMI77_RS08310	COG1216	Glycosyl transferase, family 2
DMI77_RS08315	COG0438	transferase activity, transferring glycosyl groups
DMI77_RS08320	COG1442	glycosyl transferase family 8
DMI77_RS08320	COG1216	Glycosyl transferase, family 2
DMI77_RS08325	COG0438	transferase activity, transferring glycosyl groups
DMI77_RS08330	COG1216	Glycosyl transferase, family 2
DMI77_RS08350	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DMI77_RS08355	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DMI77_RS08375	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMI77_RS08415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DMI77_RS08420	COG1872	DUF167
DMI77_RS08425	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMI77_RS08430	COG0484	heat shock protein binding
DMI77_RS08435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DMI77_RS08445	COG5434	Belongs to the glycosyl hydrolase 28 family
DMI77_RS08460	COG0277	FAD linked oxidase domain protein
DMI77_RS08485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMI77_RS08490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DMI77_RS08500	COG0131	Imidazoleglycerol-phosphate dehydratase
DMI77_RS08505	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMI77_RS08515	COG0360	Binds together with S18 to 16S ribosomal RNA
DMI77_RS08525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DMI77_RS08540	COG1686	Belongs to the peptidase S11 family
DMI77_RS08545	COG0205	6-phosphofructokinase activity
DMI77_RS08555	COG0428	transporter
DMI77_RS08560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMI77_RS08575	COG3977	Valine--pyruvate aminotransferase
DMI77_RS08580	COG1561	YicC-like family, N-terminal region
DMI77_RS08605	COG0471	metal ion transport
DMI77_RS08605	COG3273	potassium ion transport
DMI77_RS08610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI77_RS08625	COG1575	Belongs to the MenA family. Type 1 subfamily
DMI77_RS08660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI77_RS08660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI77_RS08685	COG0202	RNA polymerase activity
DMI77_RS08690	COG0203	ribosomal protein L17
DMI77_RS08695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DMI77_RS08710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMI77_RS08785	COG0667	Aldo Keto reductase
DMI77_RS08790	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DMI77_RS08795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMI77_RS08800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMI77_RS08805	COG0134	indole-3-glycerol-phosphate synthase activity
DMI77_RS08810	COG0135	phosphoribosylanthranilate isomerase activity
DMI77_RS08815	COG0133	tryptophan synthase activity
DMI77_RS08820	COG0159	tryptophan synthase activity
DMI77_RS08845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMI77_RS08850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DMI77_RS08870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DMI77_RS08905	COG0561	phosphatase activity
DMI77_RS08915	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI77_RS08920	COG2223	nitrite transmembrane transporter activity
DMI77_RS08945	COG0556	nucleotide-excision repair
DMI77_RS08955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DMI77_RS08960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DMI77_RS08985	COG1074	ATP-dependent DNA helicase activity
DMI77_RS08995	COG0697	spore germination
DMI77_RS09000	COG2373	Large extracellular alpha-helical protein
DMI77_RS09005	COG1979	alcohol dehydrogenase
DMI77_RS09150	COG0372	Belongs to the citrate synthase family
DMI77_RS09155	COG3647	Membrane
DMI77_RS09160	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DMI77_RS09170	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DMI77_RS09180	COG1187	pseudouridine synthase activity
DMI77_RS09190	COG0105	UTP biosynthetic process
DMI77_RS09195	COG1215	transferase activity, transferring glycosyl groups
DMI77_RS09200	COG0463	Glycosyl transferase, family 2
DMI77_RS09210	COG1459	type II secretion system
DMI77_RS09215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DMI77_RS09220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DMI77_RS09245	COG3468	outer membrane autotransporter barrel domain protein
DMI77_RS09255	COG0728	peptidoglycan biosynthetic process
DMI77_RS09260	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMI77_RS09260	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DMI77_RS09270	COG1649	PFAM Uncharacterised BCR, COG1649
DMI77_RS09275	COG1691	(AIR) carboxylase
DMI77_RS09280	COG1606	tRNA processing
DMI77_RS09285	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DMI77_RS09290	COG0142	geranyltranstransferase activity
DMI77_RS09305	COG1162	GTPase activity
DMI77_RS09325	COG2151	metal-sulfur cluster biosynthetic enzyme
DMI77_RS09350	COG1007	ATP synthesis coupled electron transport
DMI77_RS09355	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI77_RS09365	COG0713	ATP synthesis coupled electron transport
DMI77_RS09370	COG0839	Belongs to the complex I subunit 6 family
DMI77_RS09380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMI77_RS09385	COG1034	ATP synthesis coupled electron transport
DMI77_RS09390	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DMI77_RS09395	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DMI77_RS09400	COG0649	NAD binding
DMI77_RS09405	COG0726	polysaccharide deacetylase
DMI77_RS09415	COG0307	riboflavin synthase, alpha
DMI77_RS09420	COG2264	protein methyltransferase activity
DMI77_RS09430	COG1640	4-alpha-glucanotransferase
DMI77_RS09445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMI77_RS09450	COG1030	water channel activity
DMI77_RS09460	COG0358	DNA primase activity
DMI77_RS09465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMI77_RS09470	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DMI77_RS09500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMI77_RS09505	COG0793	Belongs to the peptidase S41A family
DMI77_RS09515	COG1643	Atp-dependent helicase
DMI77_RS09540	COG1450	Type ii and iii secretion system protein
DMI77_RS09555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DMI77_RS09580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMI77_RS09585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DMI77_RS09595	COG0268	Binds directly to 16S ribosomal RNA
DMI77_RS09600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMI77_RS09605	COG0028	Belongs to the TPP enzyme family
DMI77_RS09625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DMI77_RS09630	COG0495	leucyl-tRNA aminoacylation
DMI77_RS09635	COG3119	arylsulfatase activity
DMI77_RS09650	COG1166	arginine decarboxylase activity
DMI77_RS09660	COG3250	beta-galactosidase activity
DMI77_RS09665	COG3250	beta-galactosidase activity
DMI77_RS09670	COG3250	beta-galactosidase activity
DMI77_RS09675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DMI77_RS09680	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI77_RS09685	COG1335	isochorismatase
DMI77_RS09695	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DMI77_RS09715	COG0205	6-phosphofructokinase activity
DMI77_RS09775	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DMI77_RS09780	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DMI77_RS09785	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DMI77_RS09795	COG4771	TonB-dependent receptor
DMI77_RS09800	COG0747	negative chemotaxis
DMI77_RS09815	COG0402	S-adenosylhomocysteine deaminase activity
DMI77_RS09820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMI77_RS09835	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI77_RS09845	COG1294	oxidase, subunit
DMI77_RS09850	COG1271	oxidase subunit
DMI77_RS09860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMI77_RS09880	COG1846	Transcriptional regulator
DMI77_RS09915	COG2949	membrane
DMI77_RS09930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI77_RS09940	COG0489	protein tyrosine kinase activity
DMI77_RS09985	COG0438	transferase activity, transferring glycosyl groups
DMI77_RS10005	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMI77_RS10005	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DMI77_RS10045	COG0514	ATP-dependent DNA helicase (RecQ)
DMI77_RS10070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DMI77_RS10075	COG0045	succinate-CoA ligase (ADP-forming) activity
DMI77_RS10080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DMI77_RS10110	COG1570	exodeoxyribonuclease VII activity
DMI77_RS10135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI77_RS10140	COG2205	protein histidine kinase activity
DMI77_RS10155	COG0113	porphobilinogen synthase activity
DMI77_RS10170	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMI77_RS10190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DMI77_RS10205	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMI77_RS10220	COG4106	trans-aconitate 2-methyltransferase activity
DMI77_RS10235	COG3475	LICD family
DMI77_RS10240	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMI77_RS10250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMI77_RS10255	COG3475	LICD family
DMI77_RS10260	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DMI77_RS10270	COG2166	iron-sulfur cluster assembly
DMI77_RS10275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DMI77_RS10285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMI77_RS10290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMI77_RS10295	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DMI77_RS10300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMI77_RS10305	COG1131	(ABC) transporter
DMI77_RS10320	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DMI77_RS10335	COG1215	transferase activity, transferring glycosyl groups
DMI77_RS10345	COG2967	ApaG domain
DMI77_RS10350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMI77_RS10355	COG1522	sequence-specific DNA binding
DMI77_RS10360	COG0436	Aminotransferase
DMI77_RS10375	COG0423	glycine-tRNA ligase activity
DMI77_RS10415	COG1518	maintenance of DNA repeat elements
DMI77_RS10485	COG0586	Pfam SNARE associated Golgi protein
DMI77_RS10490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI77_RS10495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DMI77_RS10515	COG0038	chloride channel
DMI77_RS10530	COG4112	unkown
DMI77_RS10545	COG1538	Outer membrane efflux protein
DMI77_RS10555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI77_RS10565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI77_RS10585	COG3209	COG3209 Rhs family protein
DMI77_RS10605	COG0489	protein tyrosine kinase activity
DMI77_RS10610	COG0534	Mate efflux family protein
DMI77_RS10640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMI77_RS10645	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DMI77_RS10660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI77_RS10675	COG0418	dihydroorotase activity
DMI77_RS10680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMI77_RS10685	COG0513	Belongs to the DEAD box helicase family
DMI77_RS10690	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DMI77_RS10715	COG2015	COG2015, Alkyl sulfatase and related hydrolases
DMI77_RS10730	COG1703	isobutyryl-CoA mutase activity
DMI77_RS10765	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DMI77_RS10770	COG0352	thiamine-phosphate diphosphorylase activity
DMI77_RS10790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMI77_RS10795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMI77_RS10800	COG0326	Molecular chaperone. Has ATPase activity
DMI77_RS10820	COG3059	membrane
DMI77_RS10835	COG0072	phenylalanine-tRNA ligase activity
DMI77_RS10835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMI77_RS10850	COG3033	Beta-eliminating lyase
DMI77_RS10880	COG2818	Glycosylase
DMI77_RS10885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMI77_RS10920	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMI77_RS10920	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMI77_RS10925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMI77_RS10935	COG0166	Belongs to the GPI family
DMI77_RS10945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMI77_RS10945	COG0574	Belongs to the PEP-utilizing enzyme family
DMI77_RS10955	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DMI77_RS10965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMI77_RS10975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMI77_RS10985	COG5522	Integral membrane protein (intg_mem_TP0381)
DMI77_RS11005	COG0527	aspartate kinase activity
DMI77_RS11010	COG0460	homoserine dehydrogenase
DMI77_RS11020	COG3610	response to peptide
DMI77_RS11025	COG2966	Psort location CytoplasmicMembrane, score
DMI77_RS11030	COG1410	methionine synthase
DMI77_RS11030	COG0646	methionine synthase
DMI77_RS11070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DMI77_RS11075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMI77_RS11075	COG0519	Catalyzes the synthesis of GMP from XMP
DMI77_RS11095	COG0512	Glutamine amidotransferase of anthranilate synthase
DMI77_RS11095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMI77_RS11100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMI77_RS11120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMI77_RS11155	COG2195	Cleaves the N-terminal amino acid of tripeptides
DMI77_RS11160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMI77_RS11180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMI77_RS11180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMI77_RS11195	COG0037	tRNA processing
DMI77_RS11195	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DMI77_RS11210	COG1247	-acetyltransferase
DMI77_RS11250	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DMI77_RS11260	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DMI77_RS11265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DMI77_RS11265	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DMI77_RS11275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMI77_RS11285	COG1454	alcohol dehydrogenase
DMI77_RS11295	COG4974	Belongs to the 'phage' integrase family
DMI77_RS11320	COG1408	metallophosphoesterase
DMI77_RS11330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMI77_RS11345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DMI77_RS11355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMI77_RS11370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DMI77_RS11395	COG5002	protein histidine kinase activity
DMI77_RS11400	COG0745	RESPONSE REGULATOR receiver
DMI77_RS11415	COG1968	undecaprenyl-diphosphatase activity
DMI77_RS11420	COG0805	protein transport
DMI77_RS11425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI77_RS11425	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DMI77_RS11435	COG0668	transmembrane transport
DMI77_RS11440	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DMI77_RS11445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DMI77_RS11450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DMI77_RS11455	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI77_RS11460	COG0456	acetyltransferase
DMI77_RS11480	COG0538	isocitrate dehydrogenase activity
DMI77_RS11495	COG3258	Cytochrome c
DMI77_RS11520	COG1169	isochorismate synthase
DMI77_RS11540	COG0640	Transcriptional regulator
DMI77_RS11550	COG0242	peptide deformylase activity
DMI77_RS11560	COG0811	peptide transport
DMI77_RS11575	COG0151	Belongs to the GarS family
DMI77_RS11580	COG3738	Protein conserved in bacteria
DMI77_RS11585	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DMI77_RS11590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMI77_RS11605	COG0601	transmembrane transport
DMI77_RS11610	COG4239	(ABC) transporter, permease
DMI77_RS11620	COG0444	Belongs to the ABC transporter superfamily
DMI77_RS11625	COG4608	Belongs to the ABC transporter superfamily
DMI77_RS11630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMI77_RS11650	COG0697	spore germination
DMI77_RS11655	COG2132	Multicopper oxidase
DMI77_RS11660	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DMI77_RS11665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI77_RS11685	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DMI77_RS11720	COG0738	Major facilitator superfamily
DMI77_RS11765	COG1741	Belongs to the pirin family
DMI77_RS11785	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DMI77_RS11800	COG0363	glucosamine-6-phosphate deaminase activity
DMI77_RS11805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMI77_RS11810	COG1837	Belongs to the UPF0109 family
DMI77_RS11840	COG1091	dTDP-4-dehydrorhamnose reductase activity
DMI77_RS11880	COG0789	Transcriptional regulator
DMI77_RS11895	COG1408	metallophosphoesterase
DMI77_RS11905	COG0656	L-ascorbic acid biosynthetic process
DMI77_RS11920	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DMI77_RS11930	COG0697	spore germination
DMI77_RS11935	COG2311	Membrane
DMI77_RS11965	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI77_RS11965	COG2755	lipolytic protein G-D-S-L family
DMI77_RS11985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI77_RS11990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI77_RS12025	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMI77_RS12030	COG0154	amidase activity
DMI77_RS12035	COG0714	Associated with various cellular activities
DMI77_RS12050	COG2304	oxidoreductase activity
DMI77_RS12065	COG0656	L-ascorbic acid biosynthetic process
DMI77_RS12070	COG0110	maltose O-acetyltransferase activity
DMI77_RS12080	COG2207	Transcriptional regulator
DMI77_RS12090	COG1012	belongs to the aldehyde dehydrogenase family
DMI77_RS12110	COG0753	catalase activity
DMI77_RS12135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMI77_RS12140	COG1592	Rubrerythrin
DMI77_RS12155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI77_RS12230	COG0489	protein tyrosine kinase activity
DMI77_RS12235	COG4464	protein tyrosine phosphatase activity
DMI77_RS12245	COG0438	transferase activity, transferring glycosyl groups
DMI77_RS12250	COG0438	transferase activity, transferring glycosyl groups
DMI77_RS12260	COG0438	transferase activity, transferring glycosyl groups
DMI77_RS12295	COG0110	maltose O-acetyltransferase activity
DMI77_RS12305	COG1216	Glycosyl transferase, family 2
DMI77_RS12315	COG1216	Glycosyl transferase, family 2
DMI77_RS12360	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DMI77_RS12370	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DMI77_RS12375	COG0281	malic enzyme
DMI77_RS12375	COG0280	phosphate acetyltransferase
DMI77_RS12395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DMI77_RS12410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DMI77_RS12415	COG0724	RNA recognition motif
DMI77_RS12425	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DMI77_RS12430	COG1063	alcohol dehydrogenase
DMI77_RS12445	COG0714	Associated with various cellular activities
DMI77_RS12455	COG0193	aminoacyl-tRNA hydrolase activity
DMI77_RS12460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMI77_RS12475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DMI77_RS12490	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DMI77_RS12505	COG0375	protein maturation
DMI77_RS12530	COG0778	Nitroreductase
DMI77_RS12535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMI77_RS12570	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DMI77_RS12570	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DMI77_RS12590	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI77_RS12595	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DMI77_RS12600	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DMI77_RS12615	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI77_RS12620	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI77_RS12635	COG0318	PFAM AMP-dependent synthetase and ligase
DMI77_RS12660	COG0339	signal peptide processing
DMI77_RS12665	COG0110	maltose O-acetyltransferase activity
DMI77_RS12675	COG0018	arginyl-trna synthetase
DMI77_RS12715	COG4822	anaerobic cobalamin biosynthetic process
DMI77_RS12735	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DMI77_RS12750	COG1797	cobyrinic acid a,c-diamide synthase activity
DMI77_RS12755	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DMI77_RS12835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMI77_RS12850	COG0653	protein targeting
DMI77_RS12855	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DMI77_RS12855	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DMI77_RS12900	COG0740	serine-type endopeptidase activity
DMI77_RS13080	COG0494	nUDIX hydrolase