locus-tag	class	description
DMI67_RS00015	COG0070	glutamate synthase
DMI67_RS00015	COG0069	glutamate synthase activity
DMI67_RS00015	COG0067	glutamate synthase
DMI67_RS00020	COG0706	membrane insertase activity
DMI67_RS00025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DMI67_RS00035	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DMI67_RS00050	COG0657	acetylesterase activity
DMI67_RS00050	COG2755	lipolytic protein G-D-S-L family
DMI67_RS00060	COG0676	glucose-6-phosphate 1-epimerase activity
DMI67_RS00065	COG0259	pyridoxamine-phosphate oxidase activity
DMI67_RS00080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DMI67_RS00095	COG1760	l-serine dehydratase
DMI67_RS00100	COG0492	ferredoxin-NADP+ reductase activity
DMI67_RS00100	COG3118	belongs to the thioredoxin family
DMI67_RS00150	COG1408	metallophosphoesterase
DMI67_RS00160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DMI67_RS00165	COG0545	Peptidyl-prolyl cis-trans isomerase
DMI67_RS00185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMI67_RS00195	COG0826	peptidase U32
DMI67_RS00200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DMI67_RS00220	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMI67_RS00240	COG0529	Catalyzes the synthesis of activated sulfate
DMI67_RS00240	COG2895	sulfate adenylyltransferase (ATP) activity
DMI67_RS00245	COG0175	sulfate reduction
DMI67_RS00250	COG0175	sulfate reduction
DMI67_RS00270	COG0581	inorganic phosphate transmembrane transporter activity
DMI67_RS00275	COG0573	inorganic phosphate transmembrane transporter activity
DMI67_RS00285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DMI67_RS00295	COG2017	converts alpha-aldose to the beta-anomer
DMI67_RS00310	COG0612	Peptidase, M16
DMI67_RS00350	COG0233	cytoplasmic translational termination
DMI67_RS00355	COG0528	UMP kinase activity
DMI67_RS00360	COG0668	transmembrane transport
DMI67_RS00365	COG0450	alkyl hydroperoxide reductase
DMI67_RS00370	COG0733	neurotransmitter:sodium symporter activity
DMI67_RS00385	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMI67_RS00395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMI67_RS00400	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMI67_RS00405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMI67_RS00430	COG0842	Transport permease protein
DMI67_RS00435	COG0842	Transport permease protein
DMI67_RS00440	COG1131	(ABC) transporter
DMI67_RS00450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DMI67_RS00455	COG1183	phosphatidylcholine synthase activity
DMI67_RS00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DMI67_RS00475	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DMI67_RS00480	COG1028	Short-chain dehydrogenase reductase Sdr
DMI67_RS00500	COG0156	8-amino-7-oxononanoate synthase activity
DMI67_RS00520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DMI67_RS00525	COG0124	histidyl-tRNA synthetase
DMI67_RS00530	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DMI67_RS00535	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DMI67_RS00540	COG0298	carbon dioxide binding
DMI67_RS00560	COG0438	transferase activity, transferring glycosyl groups
DMI67_RS00565	COG0443	Heat shock 70 kDa protein
DMI67_RS00570	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DMI67_RS00575	COG0459	protein refolding
DMI67_RS00625	COG0632	four-way junction helicase activity
DMI67_RS00635	COG0126	phosphoglycerate kinase activity
DMI67_RS00645	COG1082	Xylose isomerase domain protein TIM barrel
DMI67_RS00655	COG0863	Belongs to the N(4) N(6)-methyltransferase family
DMI67_RS00665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DMI67_RS00675	COG2271	Major facilitator Superfamily
DMI67_RS00690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DMI67_RS00700	COG0037	tRNA processing
DMI67_RS00705	COG0254	rRNA binding
DMI67_RS00740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DMI67_RS00745	COG0039	L-malate dehydrogenase activity
DMI67_RS00765	COG0778	Nitroreductase
DMI67_RS00770	COG0564	pseudouridine synthase activity
DMI67_RS00795	COG1126	abc transporter atp-binding protein
DMI67_RS00800	COG0765	amino acid transport
DMI67_RS00810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DMI67_RS00815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DMI67_RS00865	COG1872	DUF167
DMI67_RS00870	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMI67_RS00875	COG0484	heat shock protein binding
DMI67_RS00880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DMI67_RS00890	COG5434	Belongs to the glycosyl hydrolase 28 family
DMI67_RS00905	COG0277	FAD linked oxidase domain protein
DMI67_RS00930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMI67_RS00935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DMI67_RS00945	COG0131	Imidazoleglycerol-phosphate dehydratase
DMI67_RS00950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMI67_RS00955	COG0360	Binds together with S18 to 16S ribosomal RNA
DMI67_RS00960	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DMI67_RS00975	COG1686	Belongs to the peptidase S11 family
DMI67_RS00980	COG0205	6-phosphofructokinase activity
DMI67_RS00990	COG0428	transporter
DMI67_RS00995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMI67_RS01015	COG3977	Valine--pyruvate aminotransferase
DMI67_RS01020	COG1561	YicC-like family, N-terminal region
DMI67_RS01030	COG0471	metal ion transport
DMI67_RS01030	COG3273	potassium ion transport
DMI67_RS01035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI67_RS01050	COG1575	Belongs to the MenA family. Type 1 subfamily
DMI67_RS01085	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI67_RS01085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI67_RS01105	COG0202	RNA polymerase activity
DMI67_RS01110	COG0203	ribosomal protein L17
DMI67_RS01115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DMI67_RS01125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMI67_RS01140	COG2885	chlorophyll binding
DMI67_RS01195	COG0667	Aldo Keto reductase
DMI67_RS01200	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DMI67_RS01215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMI67_RS01220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMI67_RS01225	COG0134	indole-3-glycerol-phosphate synthase activity
DMI67_RS01230	COG0135	phosphoribosylanthranilate isomerase activity
DMI67_RS01235	COG0133	tryptophan synthase activity
DMI67_RS01240	COG0159	tryptophan synthase activity
DMI67_RS01255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMI67_RS01260	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DMI67_RS01270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DMI67_RS01305	COG0561	phosphatase activity
DMI67_RS01310	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI67_RS01315	COG2223	nitrite transmembrane transporter activity
DMI67_RS01330	COG0556	nucleotide-excision repair
DMI67_RS01335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DMI67_RS01340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DMI67_RS01360	COG1074	ATP-dependent DNA helicase activity
DMI67_RS01370	COG0697	spore germination
DMI67_RS01375	COG2373	Large extracellular alpha-helical protein
DMI67_RS01380	COG1979	alcohol dehydrogenase
DMI67_RS01390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMI67_RS01415	COG0372	Belongs to the citrate synthase family
DMI67_RS01435	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DMI67_RS01445	COG1187	pseudouridine synthase activity
DMI67_RS01455	COG0105	UTP biosynthetic process
DMI67_RS01460	COG1215	transferase activity, transferring glycosyl groups
DMI67_RS01465	COG0463	Glycosyl transferase, family 2
DMI67_RS01475	COG1459	type II secretion system
DMI67_RS01480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DMI67_RS01485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DMI67_RS01490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMI67_RS01505	COG0728	peptidoglycan biosynthetic process
DMI67_RS01510	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DMI67_RS01510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMI67_RS01520	COG1649	PFAM Uncharacterised BCR, COG1649
DMI67_RS01525	COG1691	(AIR) carboxylase
DMI67_RS01530	COG1606	tRNA processing
DMI67_RS01535	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DMI67_RS01540	COG0142	geranyltranstransferase activity
DMI67_RS01555	COG2151	metal-sulfur cluster biosynthetic enzyme
DMI67_RS01575	COG1007	ATP synthesis coupled electron transport
DMI67_RS01580	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI67_RS01590	COG0713	ATP synthesis coupled electron transport
DMI67_RS01595	COG0839	Belongs to the complex I subunit 6 family
DMI67_RS01605	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMI67_RS01610	COG1034	ATP synthesis coupled electron transport
DMI67_RS01615	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DMI67_RS01620	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DMI67_RS01625	COG0649	NAD binding
DMI67_RS01635	COG0726	polysaccharide deacetylase
DMI67_RS01645	COG0307	riboflavin synthase, alpha
DMI67_RS01650	COG2264	protein methyltransferase activity
DMI67_RS01660	COG3210	domain, Protein
DMI67_RS01665	COG1640	4-alpha-glucanotransferase
DMI67_RS01675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMI67_RS01680	COG1030	water channel activity
DMI67_RS01685	COG0358	DNA primase activity
DMI67_RS01690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMI67_RS01695	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DMI67_RS01710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMI67_RS01715	COG0793	Belongs to the peptidase S41A family
DMI67_RS01730	COG1643	Atp-dependent helicase
DMI67_RS01755	COG1450	Type ii and iii secretion system protein
DMI67_RS01770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DMI67_RS01790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMI67_RS01795	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DMI67_RS01805	COG0268	Binds directly to 16S ribosomal RNA
DMI67_RS01810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMI67_RS01815	COG0028	Belongs to the TPP enzyme family
DMI67_RS01830	COG0688	phosphatidylethanolamine metabolic process
DMI67_RS01835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DMI67_RS01840	COG0495	leucyl-tRNA aminoacylation
DMI67_RS01845	COG3119	arylsulfatase activity
DMI67_RS01860	COG1166	arginine decarboxylase activity
DMI67_RS01870	COG3250	beta-galactosidase activity
DMI67_RS01875	COG3250	beta-galactosidase activity
DMI67_RS01880	COG3250	beta-galactosidase activity
DMI67_RS01885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DMI67_RS01890	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI67_RS01900	COG0205	6-phosphofructokinase activity
DMI67_RS01920	COG0535	radical SAM domain protein
DMI67_RS01960	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DMI67_RS01965	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DMI67_RS01970	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DMI67_RS01980	COG4771	TonB-dependent receptor
DMI67_RS02000	COG0402	S-adenosylhomocysteine deaminase activity
DMI67_RS02005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMI67_RS02025	COG1294	oxidase, subunit
DMI67_RS02030	COG1271	oxidase subunit
DMI67_RS02040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMI67_RS02060	COG1846	Transcriptional regulator
DMI67_RS02090	COG2949	membrane
DMI67_RS02120	COG0514	ATP-dependent DNA helicase (RecQ)
DMI67_RS02135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DMI67_RS02140	COG0045	succinate-CoA ligase (ADP-forming) activity
DMI67_RS02145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DMI67_RS02205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI67_RS02210	COG2205	protein histidine kinase activity
DMI67_RS02225	COG0113	porphobilinogen synthase activity
DMI67_RS02235	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMI67_RS02240	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DMI67_RS02255	COG0732	type I restriction modification DNA specificity domain
DMI67_RS02270	COG0732	type I restriction modification DNA specificity domain
DMI67_RS02280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DMI67_RS02305	COG4106	trans-aconitate 2-methyltransferase activity
DMI67_RS02320	COG3475	LICD family
DMI67_RS02325	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMI67_RS02335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMI67_RS02340	COG3475	LICD family
DMI67_RS02345	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DMI67_RS02355	COG2166	iron-sulfur cluster assembly
DMI67_RS02360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DMI67_RS02370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMI67_RS02375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMI67_RS02380	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DMI67_RS02385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMI67_RS02390	COG1131	(ABC) transporter
DMI67_RS02405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DMI67_RS02420	COG1215	transferase activity, transferring glycosyl groups
DMI67_RS02430	COG2967	ApaG domain
DMI67_RS02435	COG1401	restriction endodeoxyribonuclease activity
DMI67_RS02435	COG1401	restriction endodeoxyribonuclease activity
DMI67_RS02450	COG1522	sequence-specific DNA binding
DMI67_RS02455	COG0436	Aminotransferase
DMI67_RS02470	COG0423	glycine-tRNA ligase activity
DMI67_RS02475	COG0656	L-ascorbic acid biosynthetic process
DMI67_RS02490	COG2304	oxidoreductase activity
DMI67_RS02505	COG0714	Associated with various cellular activities
DMI67_RS02510	COG0154	amidase activity
DMI67_RS02515	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMI67_RS02555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI67_RS02565	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI67_RS02565	COG2755	lipolytic protein G-D-S-L family
DMI67_RS02585	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DMI67_RS02595	COG0656	L-ascorbic acid biosynthetic process
DMI67_RS02605	COG0667	Aldo Keto reductase
DMI67_RS02610	COG1408	metallophosphoesterase
DMI67_RS02630	COG2249	NAD(P)H dehydrogenase (quinone) activity
DMI67_RS02635	COG0789	Transcriptional regulator
DMI67_RS02650	COG0534	Mate efflux family protein
DMI67_RS02670	COG1091	dTDP-4-dehydrorhamnose reductase activity
DMI67_RS02685	COG1837	Belongs to the UPF0109 family
DMI67_RS02690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMI67_RS02695	COG0363	glucosamine-6-phosphate deaminase activity
DMI67_RS02715	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DMI67_RS02740	COG1070	Carbohydrate kinase
DMI67_RS02755	COG0738	Major facilitator superfamily
DMI67_RS02770	COG1595	DNA-templated transcription, initiation
DMI67_RS02785	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DMI67_RS02805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI67_RS02810	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DMI67_RS02815	COG0697	spore germination
DMI67_RS02820	COG3586	endonuclease activity
DMI67_RS02830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMI67_RS02835	COG4608	Belongs to the ABC transporter superfamily
DMI67_RS02840	COG0444	Belongs to the ABC transporter superfamily
DMI67_RS02845	COG4166	transmembrane transport
DMI67_RS02850	COG4239	(ABC) transporter, permease
DMI67_RS02855	COG0601	transmembrane transport
DMI67_RS02870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMI67_RS02875	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DMI67_RS02880	COG3738	Protein conserved in bacteria
DMI67_RS02885	COG0151	Belongs to the GarS family
DMI67_RS02900	COG0811	peptide transport
DMI67_RS02910	COG0242	peptide deformylase activity
DMI67_RS02955	COG3258	Cytochrome c
DMI67_RS02970	COG3274	enterobacterial common antigen metabolic process
DMI67_RS02975	COG0538	isocitrate dehydrogenase activity
DMI67_RS02990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI67_RS02995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DMI67_RS03000	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DMI67_RS03010	COG0668	transmembrane transport
DMI67_RS03015	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DMI67_RS03015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI67_RS03020	COG0805	protein transport
DMI67_RS03025	COG1968	undecaprenyl-diphosphatase activity
DMI67_RS03045	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DMI67_RS03055	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMI67_RS03065	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DMI67_RS03075	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMI67_RS03085	COG1408	metallophosphoesterase
DMI67_RS03110	COG4974	Belongs to the 'phage' integrase family
DMI67_RS03130	COG1454	alcohol dehydrogenase
DMI67_RS03135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMI67_RS03145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DMI67_RS03145	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DMI67_RS03150	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DMI67_RS03190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMI67_RS03200	COG4607	ABC-type enterochelin transport system periplasmic component
DMI67_RS03205	COG4604	ABC transporter, ATP-binding protein
DMI67_RS03210	COG4605	iron ion homeostasis
DMI67_RS03215	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMI67_RS03250	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMI67_RS03250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMI67_RS03265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMI67_RS03270	COG2195	Cleaves the N-terminal amino acid of tripeptides
DMI67_RS03290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMI67_RS03305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMI67_RS03330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DMI67_RS03365	COG1410	methionine synthase
DMI67_RS03365	COG0646	methionine synthase
DMI67_RS03370	COG2966	Psort location CytoplasmicMembrane, score
DMI67_RS03375	COG3610	response to peptide
DMI67_RS03390	COG0460	homoserine dehydrogenase
DMI67_RS03395	COG0527	aspartate kinase activity
DMI67_RS03405	COG5522	Integral membrane protein (intg_mem_TP0381)
DMI67_RS03415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMI67_RS03420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMI67_RS03430	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DMI67_RS03435	COG0574	Belongs to the PEP-utilizing enzyme family
DMI67_RS03435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMI67_RS03450	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMI67_RS03460	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMI67_RS03460	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMI67_RS03495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMI67_RS03500	COG2818	Glycosylase
DMI67_RS03520	COG3033	Beta-eliminating lyase
DMI67_RS03535	COG0072	phenylalanine-tRNA ligase activity
DMI67_RS03535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMI67_RS03555	COG0326	Molecular chaperone. Has ATPase activity
DMI67_RS03580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMI67_RS03585	COG1959	2 iron, 2 sulfur cluster binding
DMI67_RS03600	COG0352	thiamine-phosphate diphosphorylase activity
DMI67_RS03605	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DMI67_RS03620	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI67_RS03630	COG1703	isobutyryl-CoA mutase activity
DMI67_RS03650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DMI67_RS03660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMI67_RS03665	COG0418	dihydroorotase activity
DMI67_RS03680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI67_RS03700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMI67_RS03715	COG0534	Mate efflux family protein
DMI67_RS03720	COG0489	protein tyrosine kinase activity
DMI67_RS03730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI67_RS03745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI67_RS03755	COG1538	Outer membrane efflux protein
DMI67_RS03770	COG4112	unkown
DMI67_RS03785	COG0038	chloride channel
DMI67_RS03795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DMI67_RS03800	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI67_RS03805	COG0586	Pfam SNARE associated Golgi protein
DMI67_RS03870	COG1518	maintenance of DNA repeat elements
DMI67_RS03905	COG1012	belongs to the aldehyde dehydrogenase family
DMI67_RS03920	COG0753	catalase activity
DMI67_RS03930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMI67_RS03935	COG1592	Rubrerythrin
DMI67_RS03940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMI67_RS03975	COG0489	protein tyrosine kinase activity
DMI67_RS03985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI67_RS03995	COG2244	polysaccharide biosynthetic process
DMI67_RS04000	COG1215	transferase activity, transferring glycosyl groups
DMI67_RS04010	COG1216	Glycosyl transferase, family 2
DMI67_RS04025	COG0438	transferase activity, transferring glycosyl groups
DMI67_RS04055	COG1216	Glycosyl transferase, family 2
DMI67_RS04080	COG2755	lipolytic protein G-D-S-L family
DMI67_RS04080	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI67_RS04100	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DMI67_RS04105	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMI67_RS04110	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DMI67_RS04115	COG0281	malic enzyme
DMI67_RS04115	COG0280	phosphate acetyltransferase
DMI67_RS04130	COG1472	Belongs to the glycosyl hydrolase 3 family
DMI67_RS04135	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DMI67_RS04150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DMI67_RS04190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DMI67_RS04195	COG1063	alcohol dehydrogenase
DMI67_RS04210	COG0714	Associated with various cellular activities
DMI67_RS04220	COG0193	aminoacyl-tRNA hydrolase activity
DMI67_RS04225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMI67_RS04240	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DMI67_RS04265	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DMI67_RS04280	COG0375	protein maturation
DMI67_RS04305	COG0778	Nitroreductase
DMI67_RS04310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMI67_RS04345	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DMI67_RS04345	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DMI67_RS04365	COG0863	Belongs to the N(4) N(6)-methyltransferase family
DMI67_RS04385	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI67_RS04390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DMI67_RS04395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DMI67_RS04445	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI67_RS04450	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI67_RS04465	COG0318	PFAM AMP-dependent synthetase and ligase
DMI67_RS04485	COG0339	signal peptide processing
DMI67_RS04495	COG0018	arginyl-trna synthetase
DMI67_RS04540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMI67_RS04545	COG0653	protein targeting
DMI67_RS04560	COG0494	nUDIX hydrolase
DMI67_RS04565	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMI67_RS04570	COG1131	(ABC) transporter
DMI67_RS04590	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DMI67_RS04595	COG0564	pseudouridine synthase activity
DMI67_RS04610	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DMI67_RS04615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMI67_RS04625	COG0513	Belongs to the DEAD box helicase family
DMI67_RS04635	COG0673	inositol 2-dehydrogenase activity
DMI67_RS04670	COG1971	Probably functions as a manganese efflux pump
DMI67_RS04695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI67_RS04720	COG0442	prolyl-tRNA aminoacylation
DMI67_RS04735	COG2963	transposase activity
DMI67_RS04770	COG0531	amino acid
DMI67_RS04775	COG2066	Belongs to the glutaminase family
DMI67_RS04790	COG1115	amino acid carrier protein
DMI67_RS04800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMI67_RS04805	COG2890	protein-(glutamine-N5) methyltransferase activity
DMI67_RS04810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DMI67_RS04815	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DMI67_RS04830	COG2226	methyltransferase
DMI67_RS04835	COG0534	Mate efflux family protein
DMI67_RS04875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DMI67_RS04880	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI67_RS04900	COG1121	(ABC) transporter
DMI67_RS04905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DMI67_RS04910	COG3880	PFAM UvrB UvrC protein
DMI67_RS04915	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DMI67_RS04920	COG0542	response to heat
DMI67_RS04930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DMI67_RS04935	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMI67_RS04940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI67_RS04955	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DMI67_RS04955	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMI67_RS04965	COG0180	Tryptophanyl-tRNA synthetase
DMI67_RS04975	COG1692	metallophosphoesterase
DMI67_RS04980	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DMI67_RS05040	COG0515	serine threonine protein kinase
DMI67_RS05135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMI67_RS05140	COG2816	NAD+ diphosphatase activity
DMI67_RS05145	COG0156	8-amino-7-oxononanoate synthase activity
DMI67_RS05160	COG0515	serine threonine protein kinase
DMI67_RS05160	COG3266	domain, Protein
DMI67_RS05200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DMI67_RS05215	COG3189	MarR family transcriptional regulator
DMI67_RS05220	COG0181	hydroxymethylbilane synthase activity
DMI67_RS05225	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DMI67_RS05235	COG1469	GTP cyclohydrolase I activity
DMI67_RS05240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DMI67_RS05245	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DMI67_RS05255	COG1940	carbohydrate kinase activity
DMI67_RS05270	COG0494	nUDIX hydrolase
DMI67_RS05275	COG1566	PFAM secretion protein HlyD family protein
DMI67_RS05280	COG1136	(ABC) transporter
DMI67_RS05280	COG0577	efflux transmembrane transporter activity
DMI67_RS05285	COG0577	efflux transmembrane transporter activity
DMI67_RS05285	COG1136	(ABC) transporter
DMI67_RS05290	COG1538	Outer membrane efflux protein
DMI67_RS05305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI67_RS05345	COG1720	tRNA m6t6A37 methyltransferase activity
DMI67_RS05350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMI67_RS05355	COG0540	Belongs to the ATCase OTCase family
DMI67_RS05360	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DMI67_RS05375	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DMI67_RS05380	COG2957	Belongs to the agmatine deiminase family
DMI67_RS05390	COG0750	zinc metalloprotease
DMI67_RS05400	COG3119	arylsulfatase activity
DMI67_RS05410	COG1918	ferrous iron import across plasma membrane
DMI67_RS05410	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DMI67_RS05470	COG1475	DNA binding
DMI67_RS05505	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DMI67_RS05520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMI67_RS05525	COG0601	transmembrane transport
DMI67_RS05575	COG0849	cell division
DMI67_RS05585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMI67_RS05590	COG1132	(ABC) transporter
DMI67_RS05595	COG1132	(ABC) transporter
DMI67_RS05610	COG1127	ABC transporter
DMI67_RS05615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DMI67_RS05645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DMI67_RS05660	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DMI67_RS05665	COG0504	CTP synthase activity
DMI67_RS05670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMI67_RS05695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI67_RS05705	COG1322	Protein conserved in bacteria
DMI67_RS05710	COG0546	phosphoglycolate phosphatase activity
DMI67_RS05715	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI67_RS05725	COG4591	ABC-type transport system involved in lipoprotein release permease component
DMI67_RS05725	COG4591	ABC-type transport system involved in lipoprotein release permease component
DMI67_RS05740	COG3209	COG3209 Rhs family protein
DMI67_RS05745	COG3209	COG3209 Rhs family protein
DMI67_RS05745	COG4104	PAAR repeat-containing protein
DMI67_RS05765	COG3209	COG3209 Rhs family protein
DMI67_RS05810	COG2234	aminopeptidase activity
DMI67_RS05815	COG2755	lipolytic protein G-D-S-L family
DMI67_RS05815	COG0657	acetylesterase activity
DMI67_RS05820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DMI67_RS05840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DMI67_RS05860	COG0335	large ribosomal subunit rRNA binding
DMI67_RS05870	COG0346	lactoylglutathione lyase activity
DMI67_RS05885	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DMI67_RS05890	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DMI67_RS05900	COG0427	acetyl-CoA hydrolase
DMI67_RS05915	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DMI67_RS05925	COG0205	6-phosphofructokinase activity
DMI67_RS05935	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMI67_RS05940	COG0028	Belongs to the TPP enzyme family
DMI67_RS05960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DMI67_RS05975	COG0471	metal ion transport
DMI67_RS05985	COG0351	phosphomethylpyrimidine kinase
DMI67_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
DMI67_RS06045	COG0242	peptide deformylase activity
DMI67_RS06050	COG1063	alcohol dehydrogenase
DMI67_RS06060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMI67_RS06065	COG1393	Belongs to the ArsC family
DMI67_RS06070	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI67_RS06080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMI67_RS06090	COG1187	pseudouridine synthase activity
DMI67_RS06100	COG0336	Belongs to the RNA methyltransferase TrmD family
DMI67_RS06115	COG0539	negative regulation of cytoplasmic translation
DMI67_RS06160	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DMI67_RS06165	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DMI67_RS06170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DMI67_RS06175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMI67_RS06210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMI67_RS06290	COG3015	lipoprotein NlpE involved in copper resistance
DMI67_RS06360	COG0305	Participates in initiation and elongation during chromosome replication
DMI67_RS06460	COG0662	Cupin 2, conserved barrel domain protein
DMI67_RS06460	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DMI67_RS06470	COG0416	fatty acid biosynthetic process
DMI67_RS06475	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DMI67_RS06485	COG0537	adenosine 5'-monophosphoramidase activity
DMI67_RS06490	COG0009	L-threonylcarbamoyladenylate synthase
DMI67_RS06495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DMI67_RS06500	COG0228	four-way junction DNA binding
DMI67_RS06525	COG1862	Preprotein translocase
DMI67_RS06530	COG0343	queuine tRNA-ribosyltransferase activity
DMI67_RS06535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DMI67_RS06545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DMI67_RS06550	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMI67_RS06555	COG0776	regulation of translation
DMI67_RS06585	COG0811	peptide transport
DMI67_RS06600	COG3250	beta-galactosidase activity
DMI67_RS06605	COG0525	valine-tRNA ligase activity
DMI67_RS06615	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DMI67_RS06620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DMI67_RS06625	COG0255	Belongs to the universal ribosomal protein uL29 family
DMI67_RS06630	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DMI67_RS06635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DMI67_RS06640	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DMI67_RS06650	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DMI67_RS06655	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DMI67_RS06660	COG0089	rRNA binding
DMI67_RS06665	COG0088	Forms part of the polypeptide exit tunnel
DMI67_RS06670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DMI67_RS06675	COG0051	transcription antitermination factor activity, RNA binding
DMI67_RS06680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMI67_RS06685	COG0049	tRNA binding
DMI67_RS06690	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DMI67_RS06695	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DMI67_RS06705	COG3852	Histidine kinase
DMI67_RS06710	COG2204	response regulator
DMI67_RS06720	COG1722	exodeoxyribonuclease VII activity
DMI67_RS06725	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMI67_RS06740	COG0795	lipopolysaccharide-transporting ATPase activity
DMI67_RS06745	COG1160	GTP binding
DMI67_RS06750	COG0444	Belongs to the ABC transporter superfamily
DMI67_RS06765	COG0577	efflux transmembrane transporter activity
DMI67_RS06765	COG1136	(ABC) transporter
DMI67_RS06775	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMI67_RS06820	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DMI67_RS06825	COG0799	negative regulation of ribosome biogenesis
DMI67_RS06830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMI67_RS06880	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DMI67_RS06895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DMI67_RS06905	COG4221	oxidoreductase activity
DMI67_RS06925	COG0038	chloride channel
DMI67_RS06935	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI67_RS06950	COG0076	glutamate decarboxylase activity
DMI67_RS06965	COG0167	dihydroorotate dehydrogenase activity
DMI67_RS06970	COG0352	thiamine-phosphate diphosphorylase activity
DMI67_RS06990	COG1253	flavin adenine dinucleotide binding
DMI67_RS06995	COG1253	flavin adenine dinucleotide binding
DMI67_RS07000	COG1185	polyribonucleotide nucleotidyltransferase activity
DMI67_RS07005	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DMI67_RS07035	COG0101	tRNA pseudouridine synthase activity
DMI67_RS07040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DMI67_RS07055	COG4968	Prepilin-type N-terminal cleavage methylation domain
DMI67_RS07070	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI67_RS07075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DMI67_RS07095	COG1136	(ABC) transporter
DMI67_RS07100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DMI67_RS07110	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI67_RS07120	COG1116	anion transmembrane transporter activity
DMI67_RS07135	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI67_RS07140	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DMI67_RS07145	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DMI67_RS07155	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DMI67_RS07160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DMI67_RS07170	COG2814	Major facilitator Superfamily
DMI67_RS07180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI67_RS07185	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMI67_RS07185	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMI67_RS07190	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DMI67_RS07195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DMI67_RS07200	COG0552	protein localization to endoplasmic reticulum
DMI67_RS07205	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DMI67_RS07225	COG1546	Belongs to the CinA family
DMI67_RS07225	COG1058	Belongs to the CinA family
DMI67_RS07235	COG0456	acetyltransferase
DMI67_RS07260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DMI67_RS07265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DMI67_RS07270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMI67_RS07275	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMI67_RS07290	COG0758	DNA mediated transformation
DMI67_RS07295	COG1686	Belongs to the peptidase S11 family
DMI67_RS07300	COG0012	GTP binding
DMI67_RS07305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DMI67_RS07315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMI67_RS07315	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMI67_RS07330	COG3119	arylsulfatase activity
DMI67_RS07355	COG2259	Doxx family
DMI67_RS07360	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DMI67_RS07390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMI67_RS07410	COG2326	polyphosphate kinase activity
DMI67_RS07415	COG1349	DNA-binding transcription factor activity
DMI67_RS07440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMI67_RS07445	COG1162	GTPase activity
DMI67_RS07460	COG0742	ribosomal rna small subunit methyltransferase
DMI67_RS07475	COG2326	polyphosphate kinase activity
DMI67_RS07485	COG5434	Belongs to the glycosyl hydrolase 28 family
DMI67_RS07495	COG1073	alpha beta
DMI67_RS07500	COG0802	atpase or kinase
DMI67_RS07505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DMI67_RS07510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DMI67_RS07515	COG0735	belongs to the Fur family
DMI67_RS07520	COG0396	ATPase activity
DMI67_RS07525	COG0719	Fe-S assembly protein
DMI67_RS07530	COG0719	Fe-S assembly protein
DMI67_RS07545	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DMI67_RS07590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMI67_RS07610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DMI67_RS07615	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DMI67_RS07620	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DMI67_RS07625	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DMI67_RS07630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMI67_RS07635	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DMI67_RS07645	COG0356	it plays a direct role in the translocation of protons across the membrane
DMI67_RS07695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DMI67_RS07730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DMI67_RS07735	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DMI67_RS07740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DMI67_RS07750	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DMI67_RS07760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMI67_RS07765	COG0047	phosphoribosylformylglycinamidine synthase activity
DMI67_RS07775	COG1363	Peptidase, m42
DMI67_RS07790	COG1077	Cell shape determining protein MreB Mrl
DMI67_RS07795	COG1530	ribonuclease E activity
DMI67_RS07815	COG0848	biopolymer transport protein
DMI67_RS07830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DMI67_RS07845	COG0134	indole-3-glycerol-phosphate synthase activity
DMI67_RS07850	COG0792	nuclease activity
DMI67_RS07860	COG1253	flavin adenine dinucleotide binding
DMI67_RS07870	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DMI67_RS07875	COG0137	argininosuccinate synthase activity
DMI67_RS07890	COG0149	triose-phosphate isomerase activity
DMI67_RS07925	COG1040	competence protein
DMI67_RS07935	COG3956	TIGRFAM MazG family protein
DMI67_RS07955	COG1663	tetraacyldisaccharide 4'-kinase activity
DMI67_RS07965	COG0612	Peptidase, M16
DMI67_RS07980	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMI67_RS08010	COG0673	inositol 2-dehydrogenase activity
DMI67_RS08015	COG3034	peptidoglycan biosynthetic process
DMI67_RS08035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMI67_RS08040	COG0424	maF-like protein
DMI67_RS08045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DMI67_RS08075	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DMI67_RS08085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DMI67_RS08095	COG0571	ribonuclease III activity
DMI67_RS08115	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DMI67_RS08130	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DMI67_RS08150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMI67_RS08160	COG2226	methyltransferase
DMI67_RS08170	COG2076	Multidrug Resistance protein
DMI67_RS08245	COG2255	four-way junction helicase activity
DMI67_RS08250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMI67_RS08255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMI67_RS08260	COG1215	transferase activity, transferring glycosyl groups
DMI67_RS08265	COG0463	Glycosyl transferase, family 2
DMI67_RS08265	COG1216	Glycosyl transferase, family 2
DMI67_RS08290	COG0438	transferase activity, transferring glycosyl groups
DMI67_RS08300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI67_RS08310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DMI67_RS08320	COG0482	sulfurtransferase activity
DMI67_RS08325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DMI67_RS08335	COG2860	membrane
DMI67_RS08340	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI67_RS08345	COG2001	Belongs to the MraZ family
DMI67_RS08350	COG0275	rRNA processing
DMI67_RS08360	COG0768	penicillin binding
DMI67_RS08365	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DMI67_RS08370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DMI67_RS08375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMI67_RS08380	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DMI67_RS08390	COG0772	Belongs to the SEDS family
DMI67_RS08395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DMI67_RS08400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMI67_RS08405	COG1181	Belongs to the D-alanine--D-alanine ligase family
DMI67_RS08415	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DMI67_RS08420	COG0860	N-Acetylmuramoyl-L-alanine amidase
DMI67_RS08425	COG0321	lipoyl(octanoyl) transferase activity
DMI67_RS08430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMI67_RS08435	COG0066	3-isopropylmalate dehydratase activity
DMI67_RS08445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI67_RS08455	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMI67_RS08460	COG4608	Belongs to the ABC transporter superfamily
DMI67_RS08470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DMI67_RS08475	COG0052	Belongs to the universal ribosomal protein uS2 family
DMI67_RS08485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DMI67_RS08500	COG1137	ATPase activity
DMI67_RS08510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMI67_RS08535	COG0017	Asparaginyl-tRNA synthetase
DMI67_RS08545	COG3118	belongs to the thioredoxin family
DMI67_RS08590	COG0583	DNA-binding transcription factor activity
DMI67_RS08595	COG2855	membrane
DMI67_RS08600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DMI67_RS08610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMI67_RS08620	COG0602	queuosine metabolic process
DMI67_RS08625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMI67_RS08630	COG0217	transcriptional regulatory protein
DMI67_RS08635	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DMI67_RS08640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMI67_RS08640	COG4651	solute:proton antiporter activity
DMI67_RS08655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DMI67_RS08660	COG4864	UPF0365 protein
DMI67_RS08670	COG2022	thiamine diphosphate biosynthetic process
DMI67_RS08675	COG0531	amino acid
DMI67_RS08685	COG0628	permease
DMI67_RS08690	COG0019	diaminopimelate decarboxylase activity
DMI67_RS08695	COG0191	fructose-bisphosphate aldolase activity
DMI67_RS08700	COG1217	gtp-binding protein TYPA
DMI67_RS08730	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DMI67_RS08780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMI67_RS08785	COG0516	GMP reductase activity
DMI67_RS08785	COG0517	IMP dehydrogenase activity
DMI67_RS08790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMI67_RS08790	COG0519	Catalyzes the synthesis of GMP from XMP
DMI67_RS08815	COG0546	phosphoglycolate phosphatase activity
DMI67_RS08840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DMI67_RS08855	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DMI67_RS08860	COG0196	riboflavin kinase activity
DMI67_RS08865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DMI67_RS08880	COG1408	metallophosphoesterase
DMI67_RS08890	COG1216	Glycosyl transferase, family 2
DMI67_RS08890	COG1442	glycosyl transferase family 8
DMI67_RS08900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI67_RS08905	COG1216	Glycosyl transferase, family 2
DMI67_RS08925	COG2755	lipolytic protein G-D-S-L family
DMI67_RS08925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI67_RS08940	COG0490	domain, Protein
DMI67_RS08940	COG0471	metal ion transport
DMI67_RS08975	COG0588	phosphoglycerate mutase activity
DMI67_RS08980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMI67_RS08990	COG0477	Major facilitator Superfamily
DMI67_RS08995	COG1607	acyl-coa hydrolase
DMI67_RS09005	COG1028	Short-chain dehydrogenase reductase Sdr
DMI67_RS09015	COG1525	nuclease
DMI67_RS09025	COG1475	DNA binding
DMI67_RS09030	COG3969	phosphoadenosine phosphosulfate
DMI67_RS09045	COG0473	3-isopropylmalate dehydrogenase activity
DMI67_RS09070	COG2873	o-acetylhomoserine
DMI67_RS09075	COG0535	radical SAM domain protein
DMI67_RS09080	COG0535	radical SAM domain protein
DMI67_RS09095	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMI67_RS09100	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DMI67_RS09110	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DMI67_RS09115	COG0674	pyruvate-flavodoxin oxidoreductase activity
DMI67_RS09115	COG1013	pyruvate-flavodoxin oxidoreductase activity
DMI67_RS09115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DMI67_RS09115	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DMI67_RS09125	COG1733	regulation of RNA biosynthetic process
DMI67_RS09135	COG0107	imidazoleglycerol-phosphate synthase activity
DMI67_RS09140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMI67_RS09150	COG1643	Atp-dependent helicase
DMI67_RS09155	COG0440	acetolactate synthase activity
DMI67_RS09160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI67_RS09170	COG0445	tRNA wobble uridine modification
DMI67_RS09175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMI67_RS09175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMI67_RS09180	COG0592	DNA-directed DNA polymerase activity
DMI67_RS09205	COG1388	LysM domain
DMI67_RS09205	COG0791	NLP P60 protein
DMI67_RS09210	COG0084	hydrolase, TatD family'
DMI67_RS09220	COG3250	beta-galactosidase activity
DMI67_RS09235	COG2205	protein histidine kinase activity
DMI67_RS09240	COG0745	RESPONSE REGULATOR receiver
DMI67_RS09250	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMI67_RS09275	COG0542	response to heat
DMI67_RS09320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DMI67_RS09330	COG0659	secondary active sulfate transmembrane transporter activity
DMI67_RS09335	COG0165	Argininosuccinate lyase
DMI67_RS09350	COG0148	phosphopyruvate hydratase activity
DMI67_RS09355	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DMI67_RS09365	COG3481	metal-dependent phosphohydrolase, HD sub domain
DMI67_RS09375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMI67_RS09380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMI67_RS09455	COG0490	domain, Protein
DMI67_RS09455	COG2985	domain, Protein
DMI67_RS09470	COG0471	metal ion transport
DMI67_RS09495	COG2194	sulfuric ester hydrolase activity
DMI67_RS09500	COG1592	Rubrerythrin
DMI67_RS09510	COG1363	Peptidase, m42
DMI67_RS09515	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI67_RS09525	COG1785	Belongs to the alkaline phosphatase family
DMI67_RS09530	COG1970	mechanosensitive ion channel activity
DMI67_RS09535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMI67_RS09545	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DMI67_RS09555	COG2217	Heavy metal translocating P-type atpase
DMI67_RS09560	COG0497	DNA recombination
DMI67_RS09565	COG0321	lipoyl(octanoyl) transferase activity
DMI67_RS09565	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DMI67_RS09570	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DMI67_RS09600	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI67_RS09605	COG0022	dehydrogenase e1 component
DMI67_RS09610	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMI67_RS09620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI67_RS09625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMI67_RS09630	COG3210	domain, Protein
DMI67_RS09680	COG5632	N-Acetylmuramoyl-L-alanine amidase
DMI67_RS09680	COG3409	Peptidoglycan-binding domain 1 protein
DMI67_RS09685	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DMI67_RS09715	COG1690	Belongs to the RtcB family
DMI67_RS09725	COG2814	Major facilitator Superfamily
DMI67_RS09735	COG2096	Adenosyltransferase
DMI67_RS09745	COG0557	exoribonuclease II activity
DMI67_RS09770	COG0826	peptidase U32
DMI67_RS09775	COG0285	dihydrofolate synthase activity
DMI67_RS09790	COG0673	inositol 2-dehydrogenase activity
DMI67_RS09795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMI67_RS09800	COG0737	Belongs to the 5'-nucleotidase family
DMI67_RS09810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMI67_RS09815	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DMI67_RS09830	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DMI67_RS09835	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DMI67_RS09840	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DMI67_RS09845	COG0200	Binds to the 23S rRNA
DMI67_RS09850	COG0201	protein transport
DMI67_RS09855	COG0563	adenylate kinase activity
DMI67_RS09860	COG0024	Methionine aminopeptidase
DMI67_RS09875	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DMI67_RS09880	COG1442	glycosyl transferase family 8
DMI67_RS09890	COG1216	Glycosyl transferase, family 2
DMI67_RS09900	COG1216	Glycosyl transferase, family 2
DMI67_RS09915	COG1216	Glycosyl transferase, family 2
DMI67_RS09920	COG0693	protein deglycase activity
DMI67_RS09925	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI67_RS09930	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DMI67_RS09935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMI67_RS09945	COG1966	Carbon starvation protein
DMI67_RS09955	COG3119	arylsulfatase activity
DMI67_RS09960	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DMI67_RS09965	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DMI67_RS09970	COG0195	Participates in both transcription termination and antitermination
DMI67_RS09975	COG0708	Exodeoxyribonuclease III
DMI67_RS09980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DMI67_RS09985	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DMI67_RS09990	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DMI67_RS10000	COG0842	Transport permease protein
DMI67_RS10000	COG1131	(ABC) transporter
DMI67_RS10000	COG1716	ATPase activity
DMI67_RS10020	COG0724	RNA recognition motif
DMI67_RS10025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI67_RS10045	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DMI67_RS10055	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DMI67_RS10060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMI67_RS10075	COG1490	D-aminoacyl-tRNA deacylase activity
DMI67_RS10085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMI67_RS10090	COG1053	succinate dehydrogenase
DMI67_RS10135	COG1028	Short-chain dehydrogenase reductase Sdr
DMI67_RS10145	COG0488	(ABC) transporter
DMI67_RS10155	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DMI67_RS10165	COG1253	flavin adenine dinucleotide binding
DMI67_RS10170	COG1028	Short-chain dehydrogenase reductase Sdr
DMI67_RS10180	COG1073	alpha beta
DMI67_RS10190	COG0667	Aldo Keto reductase
DMI67_RS10245	COG2267	carboxylic ester hydrolase activity
DMI67_RS10250	COG2095	MarC family integral membrane protein
DMI67_RS10280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMI67_RS10285	COG0488	(ABC) transporter
DMI67_RS10350	COG0215	cysteine-tRNA ligase activity
DMI67_RS10360	COG3119	arylsulfatase activity
DMI67_RS10375	COG0481	GTPase activity
DMI67_RS10400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMI67_RS10405	COG0085	RNA polymerase activity
DMI67_RS10410	COG0222	ribosome binding
DMI67_RS10415	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DMI67_RS10420	COG0081	regulation of translation
DMI67_RS10425	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DMI67_RS10430	COG0250	Participates in transcription elongation, termination and antitermination
DMI67_RS10445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMI67_RS10455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DMI67_RS10465	COG0740	serine-type endopeptidase activity
DMI67_RS10470	COG0544	peptidyl-prolyl cis-trans isomerase activity
DMI67_RS10485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DMI67_RS10505	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMI67_RS10550	COG2226	methyltransferase
DMI67_RS10555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DMI67_RS10560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DMI67_RS10575	COG1902	pentaerythritol trinitrate reductase activity
DMI67_RS10575	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMI67_RS10585	COG3119	arylsulfatase activity
DMI67_RS10590	COG0514	ATP-dependent DNA helicase (RecQ)
DMI67_RS10610	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DMI67_RS10615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMI67_RS10670	COG1858	cytochrome C peroxidase
DMI67_RS10675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DMI67_RS10680	COG0590	tRNA wobble adenosine to inosine editing
DMI67_RS10685	COG1940	carbohydrate kinase activity
DMI67_RS10690	COG2217	Heavy metal translocating P-type atpase
DMI67_RS10695	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMI67_RS10725	COG1363	Peptidase, m42
DMI67_RS10730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DMI67_RS10740	COG0006	proline dipeptidase activity
DMI67_RS10745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DMI67_RS10770	COG5002	protein histidine kinase activity
DMI67_RS10775	COG0745	RESPONSE REGULATOR receiver
DMI67_RS10780	COG0129	dihydroxy-acid dehydratase activity
DMI67_RS10875	COG1368	sulfuric ester hydrolase activity
DMI67_RS10910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DMI67_RS10915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DMI67_RS10935	COG0534	Mate efflux family protein
DMI67_RS10940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMI67_RS10955	COG1876	peptidase activity
DMI67_RS11095	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMI67_RS11100	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DMI67_RS11105	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DMI67_RS11110	COG2205	protein histidine kinase activity
DMI67_RS11115	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DMI67_RS11125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMI67_RS11140	COG0667	Aldo Keto reductase
DMI67_RS11145	COG0789	Transcriptional regulator
DMI67_RS11190	COG0714	Associated with various cellular activities
DMI67_RS11195	COG2311	Membrane
DMI67_RS11215	COG1090	epimerase
DMI67_RS11225	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DMI67_RS11230	COG1119	ATPase activity
DMI67_RS11235	COG2186	Transcriptional regulator
DMI67_RS11260	COG0148	phosphopyruvate hydratase activity
DMI67_RS11265	COG0436	Aminotransferase
DMI67_RS11270	COG1477	protein flavinylation
DMI67_RS11285	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DMI67_RS11295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DMI67_RS11315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DMI67_RS11325	COG1199	ATP-dependent helicase activity
DMI67_RS11330	COG1122	ATPase activity
DMI67_RS11355	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DMI67_RS11360	COG0598	Magnesium transport protein CorA
DMI67_RS11365	COG0359	binds to the 23S rRNA
DMI67_RS11370	COG0138	bifunctional purine biosynthesis protein purh
DMI67_RS11375	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DMI67_RS11380	COG0736	holo-[acyl-carrier-protein] synthase activity
DMI67_RS11390	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DMI67_RS11395	COG5632	N-Acetylmuramoyl-L-alanine amidase
DMI67_RS11395	COG3409	Peptidoglycan-binding domain 1 protein
DMI67_RS11400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DMI67_RS11410	COG0437	4 iron, 4 sulfur cluster binding
DMI67_RS11430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMI67_RS11480	COG0284	orotidine-5'-phosphate decarboxylase activity
DMI67_RS11500	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DMI67_RS11505	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DMI67_RS11525	COG2003	Belongs to the UPF0758 family
DMI67_RS11530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DMI67_RS11530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DMI67_RS11535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DMI67_RS11540	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DMI67_RS11545	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DMI67_RS11550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DMI67_RS11555	COG0322	excinuclease ABC activity
DMI67_RS11560	COG0811	peptide transport
DMI67_RS11565	COG0848	biopolymer transport protein
DMI67_RS11575	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DMI67_RS11580	COG0483	inositol monophosphate 1-phosphatase activity
DMI67_RS11585	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMI67_RS11595	COG1482	cell wall glycoprotein biosynthetic process
DMI67_RS11605	COG1757	Na H antiporter
DMI67_RS11610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI67_RS11615	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DMI67_RS11620	COG0505	Belongs to the CarA family
DMI67_RS11625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMI67_RS11640	COG0070	glutamate synthase
DMI67_RS11640	COG0067	glutamate synthase
DMI67_RS11640	COG0069	glutamate synthase activity
DMI67_RS11645	COG0706	membrane insertase activity
DMI67_RS11650	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DMI67_RS11660	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DMI67_RS11675	COG0657	acetylesterase activity
DMI67_RS11675	COG2755	lipolytic protein G-D-S-L family
DMI67_RS11685	COG0676	glucose-6-phosphate 1-epimerase activity
DMI67_RS11690	COG0259	pyridoxamine-phosphate oxidase activity
DMI67_RS11705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DMI67_RS11720	COG1760	l-serine dehydratase
DMI67_RS11725	COG3118	belongs to the thioredoxin family
DMI67_RS11725	COG0492	ferredoxin-NADP+ reductase activity
DMI67_RS11785	COG1408	metallophosphoesterase
DMI67_RS11800	COG0545	Peptidyl-prolyl cis-trans isomerase
DMI67_RS11870	COG1715	Restriction endonuclease
DMI67_RS11875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters