locus-tag	class	description
GOZ73_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GOZ73_RS00010	COG1131	(ABC) transporter
GOZ73_RS00030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GOZ73_RS00035	COG0564	pseudouridine synthase activity
GOZ73_RS00050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GOZ73_RS00055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GOZ73_RS00060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GOZ73_RS00090	COG0673	inositol 2-dehydrogenase activity
GOZ73_RS00110	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GOZ73_RS00125	COG1971	Probably functions as a manganese efflux pump
GOZ73_RS00150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOZ73_RS00175	COG0442	prolyl-tRNA aminoacylation
GOZ73_RS00195	COG0531	amino acid
GOZ73_RS00200	COG2066	Belongs to the glutaminase family
GOZ73_RS00210	COG1115	amino acid carrier protein
GOZ73_RS00220	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GOZ73_RS00225	COG2890	protein-(glutamine-N5) methyltransferase activity
GOZ73_RS00230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GOZ73_RS00235	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GOZ73_RS00250	COG2226	methyltransferase
GOZ73_RS00255	COG0534	Mate efflux family protein
GOZ73_RS00295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GOZ73_RS00300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GOZ73_RS00305	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GOZ73_RS00320	COG1121	(ABC) transporter
GOZ73_RS00325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GOZ73_RS00330	COG3880	PFAM UvrB UvrC protein
GOZ73_RS00335	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GOZ73_RS00340	COG0542	response to heat
GOZ73_RS00355	COG0179	Fumarylacetoacetate (FAA) hydrolase
GOZ73_RS00360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GOZ73_RS00375	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GOZ73_RS00375	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GOZ73_RS00390	COG0180	Tryptophanyl-tRNA synthetase
GOZ73_RS00400	COG1692	metallophosphoesterase
GOZ73_RS00405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GOZ73_RS00420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GOZ73_RS00425	COG2816	NAD+ diphosphatase activity
GOZ73_RS00430	COG0156	8-amino-7-oxononanoate synthase activity
GOZ73_RS00445	COG0515	serine threonine protein kinase
GOZ73_RS00445	COG3266	domain, Protein
GOZ73_RS00455	COG4974	Belongs to the 'phage' integrase family
GOZ73_RS00475	COG0326	Molecular chaperone. Has ATPase activity
GOZ73_RS00510	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GOZ73_RS00520	COG3189	MarR family transcriptional regulator
GOZ73_RS00530	COG0181	hydroxymethylbilane synthase activity
GOZ73_RS00535	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GOZ73_RS00545	COG1469	GTP cyclohydrolase I activity
GOZ73_RS00550	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GOZ73_RS00555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GOZ73_RS00560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GOZ73_RS00565	COG1940	carbohydrate kinase activity
GOZ73_RS00580	COG0494	nUDIX hydrolase
GOZ73_RS00590	COG1566	PFAM secretion protein HlyD family protein
GOZ73_RS00595	COG0577	efflux transmembrane transporter activity
GOZ73_RS00595	COG1136	(ABC) transporter
GOZ73_RS00600	COG1136	(ABC) transporter
GOZ73_RS00600	COG0577	efflux transmembrane transporter activity
GOZ73_RS00605	COG1538	Outer membrane efflux protein
GOZ73_RS00620	COG1720	tRNA m6t6A37 methyltransferase activity
GOZ73_RS00625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GOZ73_RS00630	COG0540	Belongs to the ATCase OTCase family
GOZ73_RS00635	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GOZ73_RS00650	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GOZ73_RS00655	COG2957	Belongs to the agmatine deiminase family
GOZ73_RS00665	COG0750	zinc metalloprotease
GOZ73_RS00675	COG3119	arylsulfatase activity
GOZ73_RS00685	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GOZ73_RS00685	COG1918	ferrous iron import across plasma membrane
GOZ73_RS00735	COG1475	DNA binding
GOZ73_RS00770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GOZ73_RS00780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GOZ73_RS00785	COG0601	transmembrane transport
GOZ73_RS00840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GOZ73_RS00845	COG1132	(ABC) transporter
GOZ73_RS00850	COG1132	(ABC) transporter
GOZ73_RS00865	COG1127	ABC transporter
GOZ73_RS00870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GOZ73_RS00900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GOZ73_RS00915	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GOZ73_RS00920	COG0504	CTP synthase activity
GOZ73_RS00925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GOZ73_RS00950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GOZ73_RS00960	COG1322	Protein conserved in bacteria
GOZ73_RS00965	COG0546	phosphoglycolate phosphatase activity
GOZ73_RS00970	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GOZ73_RS00980	COG4591	ABC-type transport system involved in lipoprotein release permease component
GOZ73_RS00980	COG4591	ABC-type transport system involved in lipoprotein release permease component
GOZ73_RS01005	COG2755	lipolytic protein G-D-S-L family
GOZ73_RS01005	COG0657	acetylesterase activity
GOZ73_RS01010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GOZ73_RS01030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GOZ73_RS01035	COG2267	carboxylic ester hydrolase activity
GOZ73_RS01050	COG0335	large ribosomal subunit rRNA binding
GOZ73_RS01060	COG0346	lactoylglutathione lyase activity
GOZ73_RS01075	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GOZ73_RS01080	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GOZ73_RS01085	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GOZ73_RS01085	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GOZ73_RS01090	COG0427	acetyl-CoA hydrolase
GOZ73_RS01100	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GOZ73_RS01110	COG0205	6-phosphofructokinase activity
GOZ73_RS01125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GOZ73_RS01130	COG0028	Belongs to the TPP enzyme family
GOZ73_RS01150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GOZ73_RS01165	COG0471	metal ion transport
GOZ73_RS01175	COG0351	phosphomethylpyrimidine kinase
GOZ73_RS01235	COG1028	Short-chain dehydrogenase reductase Sdr
GOZ73_RS01245	COG0242	peptide deformylase activity
GOZ73_RS01250	COG1063	alcohol dehydrogenase
GOZ73_RS01260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GOZ73_RS01265	COG1393	Belongs to the ArsC family
GOZ73_RS01270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GOZ73_RS01275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GOZ73_RS01285	COG1187	pseudouridine synthase activity
GOZ73_RS01295	COG0336	Belongs to the RNA methyltransferase TrmD family
GOZ73_RS01300	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GOZ73_RS01310	COG0539	negative regulation of cytoplasmic translation
GOZ73_RS01355	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GOZ73_RS01360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GOZ73_RS01365	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GOZ73_RS01370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GOZ73_RS01405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOZ73_RS01485	COG3015	lipoprotein NlpE involved in copper resistance
GOZ73_RS01555	COG0305	Participates in initiation and elongation during chromosome replication
GOZ73_RS01660	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GOZ73_RS01660	COG0662	Cupin 2, conserved barrel domain protein
GOZ73_RS01670	COG0416	fatty acid biosynthetic process
GOZ73_RS01675	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GOZ73_RS01685	COG0537	adenosine 5'-monophosphoramidase activity
GOZ73_RS01690	COG0009	L-threonylcarbamoyladenylate synthase
GOZ73_RS01695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GOZ73_RS01700	COG0228	four-way junction DNA binding
GOZ73_RS01720	COG1862	Preprotein translocase
GOZ73_RS01725	COG0343	queuine tRNA-ribosyltransferase activity
GOZ73_RS01730	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GOZ73_RS01740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GOZ73_RS01745	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GOZ73_RS01750	COG0776	regulation of translation
GOZ73_RS01780	COG0811	peptide transport
GOZ73_RS01795	COG3250	beta-galactosidase activity
GOZ73_RS01800	COG0525	valine-tRNA ligase activity
GOZ73_RS01810	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GOZ73_RS01815	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GOZ73_RS01820	COG0255	Belongs to the universal ribosomal protein uL29 family
GOZ73_RS01825	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GOZ73_RS01830	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GOZ73_RS01835	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GOZ73_RS01845	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GOZ73_RS01850	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GOZ73_RS01855	COG0089	rRNA binding
GOZ73_RS01860	COG0088	Forms part of the polypeptide exit tunnel
GOZ73_RS01865	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GOZ73_RS01870	COG0051	transcription antitermination factor activity, RNA binding
GOZ73_RS01875	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GOZ73_RS01880	COG0049	tRNA binding
GOZ73_RS01885	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GOZ73_RS01890	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GOZ73_RS01900	COG3852	Histidine kinase
GOZ73_RS01905	COG2204	response regulator
GOZ73_RS01915	COG1722	exodeoxyribonuclease VII activity
GOZ73_RS01920	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GOZ73_RS01935	COG0795	lipopolysaccharide-transporting ATPase activity
GOZ73_RS01940	COG1160	GTP binding
GOZ73_RS01945	COG0444	Belongs to the ABC transporter superfamily
GOZ73_RS01965	COG0577	efflux transmembrane transporter activity
GOZ73_RS01965	COG1136	(ABC) transporter
GOZ73_RS01975	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GOZ73_RS02020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GOZ73_RS02025	COG0799	negative regulation of ribosome biogenesis
GOZ73_RS02030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GOZ73_RS02080	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GOZ73_RS02095	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GOZ73_RS02105	COG0300	oxidoreductase activity
GOZ73_RS02125	COG0038	chloride channel
GOZ73_RS02135	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GOZ73_RS02150	COG0076	glutamate decarboxylase activity
GOZ73_RS02165	COG0167	dihydroorotate dehydrogenase activity
GOZ73_RS02170	COG0352	thiamine-phosphate diphosphorylase activity
GOZ73_RS02190	COG1253	flavin adenine dinucleotide binding
GOZ73_RS02195	COG1253	flavin adenine dinucleotide binding
GOZ73_RS02205	COG1185	polyribonucleotide nucleotidyltransferase activity
GOZ73_RS02210	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GOZ73_RS02215	COG0110	maltose O-acetyltransferase activity
GOZ73_RS02240	COG0101	tRNA pseudouridine synthase activity
GOZ73_RS02245	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GOZ73_RS02265	COG4968	Prepilin-type N-terminal cleavage methylation domain
GOZ73_RS02280	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GOZ73_RS02285	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GOZ73_RS02305	COG1136	(ABC) transporter
GOZ73_RS02310	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GOZ73_RS02320	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GOZ73_RS02345	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GOZ73_RS02350	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GOZ73_RS02355	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GOZ73_RS02365	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GOZ73_RS02370	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GOZ73_RS02380	COG2814	Major facilitator Superfamily
GOZ73_RS02390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GOZ73_RS02395	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GOZ73_RS02395	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GOZ73_RS02400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GOZ73_RS02405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GOZ73_RS02410	COG0552	protein localization to endoplasmic reticulum
GOZ73_RS02415	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GOZ73_RS02460	COG1058	Belongs to the CinA family
GOZ73_RS02460	COG1546	Belongs to the CinA family
GOZ73_RS02470	COG0456	acetyltransferase
GOZ73_RS02495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GOZ73_RS02500	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GOZ73_RS02505	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GOZ73_RS02510	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GOZ73_RS02525	COG0758	DNA mediated transformation
GOZ73_RS02530	COG1686	Belongs to the peptidase S11 family
GOZ73_RS02535	COG0012	GTP binding
GOZ73_RS02540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GOZ73_RS02550	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GOZ73_RS02550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GOZ73_RS02565	COG3119	arylsulfatase activity
GOZ73_RS02590	COG2259	Doxx family
GOZ73_RS02595	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GOZ73_RS02625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GOZ73_RS02645	COG2326	polyphosphate kinase activity
GOZ73_RS02650	COG1349	DNA-binding transcription factor activity
GOZ73_RS02665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GOZ73_RS02670	COG1162	GTPase activity
GOZ73_RS02685	COG0742	ribosomal rna small subunit methyltransferase
GOZ73_RS02700	COG2326	polyphosphate kinase activity
GOZ73_RS02710	COG5434	Belongs to the glycosyl hydrolase 28 family
GOZ73_RS02720	COG1073	alpha beta
GOZ73_RS02725	COG0802	atpase or kinase
GOZ73_RS02730	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GOZ73_RS02735	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GOZ73_RS02740	COG0735	belongs to the Fur family
GOZ73_RS02745	COG0396	ATPase activity
GOZ73_RS02750	COG0719	Fe-S assembly protein
GOZ73_RS02755	COG0719	Fe-S assembly protein
GOZ73_RS02770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GOZ73_RS02810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GOZ73_RS02830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GOZ73_RS02835	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GOZ73_RS02840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GOZ73_RS02845	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GOZ73_RS02850	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GOZ73_RS02855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GOZ73_RS02865	COG0356	it plays a direct role in the translocation of protons across the membrane
GOZ73_RS02925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GOZ73_RS02955	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GOZ73_RS02960	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GOZ73_RS02965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GOZ73_RS02975	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GOZ73_RS02985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GOZ73_RS02990	COG0047	phosphoribosylformylglycinamidine synthase activity
GOZ73_RS03000	COG1363	Peptidase, m42
GOZ73_RS03015	COG1077	Cell shape determining protein MreB Mrl
GOZ73_RS03020	COG1530	ribonuclease E activity
GOZ73_RS03040	COG0848	biopolymer transport protein
GOZ73_RS03055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GOZ73_RS03070	COG0134	indole-3-glycerol-phosphate synthase activity
GOZ73_RS03075	COG0792	nuclease activity
GOZ73_RS03085	COG1253	flavin adenine dinucleotide binding
GOZ73_RS03095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GOZ73_RS03100	COG0137	argininosuccinate synthase activity
GOZ73_RS03115	COG0149	triose-phosphate isomerase activity
GOZ73_RS03150	COG1040	competence protein
GOZ73_RS03160	COG3956	TIGRFAM MazG family protein
GOZ73_RS03180	COG1663	tetraacyldisaccharide 4'-kinase activity
GOZ73_RS03185	COG0612	Peptidase, M16
GOZ73_RS03210	COG0673	inositol 2-dehydrogenase activity
GOZ73_RS03215	COG3034	peptidoglycan biosynthetic process
GOZ73_RS03235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GOZ73_RS03240	COG0424	maF-like protein
GOZ73_RS03245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GOZ73_RS03275	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GOZ73_RS03285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GOZ73_RS03295	COG0571	ribonuclease III activity
GOZ73_RS03305	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GOZ73_RS03375	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GOZ73_RS03390	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GOZ73_RS03410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GOZ73_RS03425	COG2226	methyltransferase
GOZ73_RS03435	COG2076	Multidrug Resistance protein
GOZ73_RS03485	COG2255	four-way junction helicase activity
GOZ73_RS03490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GOZ73_RS03495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GOZ73_RS03500	COG1215	transferase activity, transferring glycosyl groups
GOZ73_RS03510	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GOZ73_RS03520	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GOZ73_RS03530	COG0438	transferase activity, transferring glycosyl groups
GOZ73_RS03555	COG1216	Glycosyl transferase, family 2
GOZ73_RS03555	COG0463	Glycosyl transferase, family 2
GOZ73_RS03585	COG1053	succinate dehydrogenase
GOZ73_RS03590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GOZ73_RS03630	COG1490	D-aminoacyl-tRNA deacylase activity
GOZ73_RS03645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOZ73_RS03650	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GOZ73_RS03660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GOZ73_RS03680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GOZ73_RS03685	COG0724	RNA recognition motif
GOZ73_RS03705	COG1716	ATPase activity
GOZ73_RS03705	COG0842	Transport permease protein
GOZ73_RS03705	COG1131	(ABC) transporter
GOZ73_RS03715	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
GOZ73_RS03720	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GOZ73_RS03725	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GOZ73_RS03730	COG0708	Exodeoxyribonuclease III
GOZ73_RS03735	COG0195	Participates in both transcription termination and antitermination
GOZ73_RS03740	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GOZ73_RS03745	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GOZ73_RS03755	COG3119	arylsulfatase activity
GOZ73_RS03770	COG1966	Carbon starvation protein
GOZ73_RS03780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GOZ73_RS03785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GOZ73_RS03790	COG0508	dehydrogenase complex catalyzes the overall conversion of
GOZ73_RS03795	COG0693	protein deglycase activity
GOZ73_RS03800	COG1216	Glycosyl transferase, family 2
GOZ73_RS03815	COG1216	Glycosyl transferase, family 2
GOZ73_RS03825	COG1216	Glycosyl transferase, family 2
GOZ73_RS03835	COG1442	glycosyl transferase family 8
GOZ73_RS03840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GOZ73_RS03855	COG0024	Methionine aminopeptidase
GOZ73_RS03860	COG0563	adenylate kinase activity
GOZ73_RS03865	COG0201	protein transport
GOZ73_RS03870	COG0200	Binds to the 23S rRNA
GOZ73_RS03875	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GOZ73_RS03880	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GOZ73_RS03885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GOZ73_RS03900	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GOZ73_RS03905	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GOZ73_RS03915	COG0737	Belongs to the 5'-nucleotidase family
GOZ73_RS03920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GOZ73_RS03925	COG0673	inositol 2-dehydrogenase activity
GOZ73_RS03940	COG0285	dihydrofolate synthase activity
GOZ73_RS03945	COG0826	peptidase U32
GOZ73_RS03950	COG0557	exoribonuclease II activity
GOZ73_RS03960	COG2096	Adenosyltransferase
GOZ73_RS03970	COG2814	Major facilitator Superfamily
GOZ73_RS03980	COG1690	Belongs to the RtcB family
GOZ73_RS04005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GOZ73_RS04010	COG3409	Peptidoglycan-binding domain 1 protein
GOZ73_RS04010	COG5632	N-Acetylmuramoyl-L-alanine amidase
GOZ73_RS04055	COG2738	Putative neutral zinc metallopeptidase
GOZ73_RS04065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GOZ73_RS04070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOZ73_RS04075	COG0789	Transcriptional regulator
GOZ73_RS04080	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GOZ73_RS04085	COG0022	dehydrogenase e1 component
GOZ73_RS04090	COG0508	dehydrogenase complex catalyzes the overall conversion of
GOZ73_RS04120	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GOZ73_RS04125	COG0321	lipoyl(octanoyl) transferase activity
GOZ73_RS04125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GOZ73_RS04130	COG0497	DNA recombination
GOZ73_RS04135	COG2217	Heavy metal translocating P-type atpase
GOZ73_RS04145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GOZ73_RS04155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GOZ73_RS04160	COG1970	mechanosensitive ion channel activity
GOZ73_RS04165	COG1785	Belongs to the alkaline phosphatase family
GOZ73_RS04175	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GOZ73_RS04180	COG1363	Peptidase, m42
GOZ73_RS04190	COG1592	Rubrerythrin
GOZ73_RS04195	COG2194	sulfuric ester hydrolase activity
GOZ73_RS04220	COG0471	metal ion transport
GOZ73_RS04235	COG0490	domain, Protein
GOZ73_RS04235	COG2985	domain, Protein
GOZ73_RS04265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GOZ73_RS04270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GOZ73_RS04280	COG3481	metal-dependent phosphohydrolase, HD sub domain
GOZ73_RS04290	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GOZ73_RS04295	COG0148	phosphopyruvate hydratase activity
GOZ73_RS04310	COG0165	Argininosuccinate lyase
GOZ73_RS04315	COG0659	secondary active sulfate transmembrane transporter activity
GOZ73_RS04325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GOZ73_RS04370	COG0542	response to heat
GOZ73_RS04395	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GOZ73_RS04405	COG0745	RESPONSE REGULATOR receiver
GOZ73_RS04410	COG2205	protein histidine kinase activity
GOZ73_RS04425	COG3250	beta-galactosidase activity
GOZ73_RS04435	COG0084	hydrolase, TatD family'
GOZ73_RS04440	COG0791	NLP P60 protein
GOZ73_RS04440	COG1388	LysM domain
GOZ73_RS04465	COG0592	DNA-directed DNA polymerase activity
GOZ73_RS04475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GOZ73_RS04480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GOZ73_RS04480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GOZ73_RS04485	COG0445	tRNA wobble uridine modification
GOZ73_RS04495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GOZ73_RS04500	COG0440	acetolactate synthase activity
GOZ73_RS04505	COG1643	Atp-dependent helicase
GOZ73_RS04515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GOZ73_RS04525	COG0107	imidazoleglycerol-phosphate synthase activity
GOZ73_RS04535	COG1733	regulation of RNA biosynthetic process
GOZ73_RS04545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GOZ73_RS04545	COG1013	pyruvate-flavodoxin oxidoreductase activity
GOZ73_RS04545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GOZ73_RS04545	COG0674	pyruvate-flavodoxin oxidoreductase activity
GOZ73_RS04550	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GOZ73_RS04560	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GOZ73_RS04565	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GOZ73_RS04580	COG0535	radical SAM domain protein
GOZ73_RS04585	COG0535	radical SAM domain protein
GOZ73_RS04590	COG2873	o-acetylhomoserine
GOZ73_RS04615	COG0473	3-isopropylmalate dehydrogenase activity
GOZ73_RS04625	COG3969	phosphoadenosine phosphosulfate
GOZ73_RS04630	COG1475	DNA binding
GOZ73_RS04645	COG1525	nuclease
GOZ73_RS04655	COG1028	Short-chain dehydrogenase reductase Sdr
GOZ73_RS04665	COG1607	acyl-coa hydrolase
GOZ73_RS04670	COG0477	Major facilitator Superfamily
GOZ73_RS04680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GOZ73_RS04685	COG0588	phosphoglycerate mutase activity
GOZ73_RS04720	COG0490	domain, Protein
GOZ73_RS04720	COG0471	metal ion transport
GOZ73_RS04735	COG2755	lipolytic protein G-D-S-L family
GOZ73_RS04735	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GOZ73_RS04755	COG1216	Glycosyl transferase, family 2
GOZ73_RS04760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOZ73_RS04770	COG1216	Glycosyl transferase, family 2
GOZ73_RS04770	COG1442	glycosyl transferase family 8
GOZ73_RS04780	COG1408	metallophosphoesterase
GOZ73_RS04795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GOZ73_RS04800	COG0196	riboflavin kinase activity
GOZ73_RS04805	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GOZ73_RS04820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GOZ73_RS04840	COG0546	phosphoglycolate phosphatase activity
GOZ73_RS04850	COG0519	Catalyzes the synthesis of GMP from XMP
GOZ73_RS04850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GOZ73_RS04855	COG0516	GMP reductase activity
GOZ73_RS04855	COG0517	IMP dehydrogenase activity
GOZ73_RS04860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GOZ73_RS04890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GOZ73_RS04920	COG1217	gtp-binding protein TYPA
GOZ73_RS04925	COG0191	fructose-bisphosphate aldolase activity
GOZ73_RS04930	COG0019	diaminopimelate decarboxylase activity
GOZ73_RS04935	COG0628	permease
GOZ73_RS04945	COG0531	amino acid
GOZ73_RS04950	COG2022	thiamine diphosphate biosynthetic process
GOZ73_RS04960	COG4864	UPF0365 protein
GOZ73_RS04965	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GOZ73_RS04975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GOZ73_RS04975	COG4651	solute:proton antiporter activity
GOZ73_RS04980	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GOZ73_RS04985	COG0217	transcriptional regulatory protein
GOZ73_RS04990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GOZ73_RS04995	COG0602	queuosine metabolic process
GOZ73_RS05005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GOZ73_RS05015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GOZ73_RS05020	COG2855	membrane
GOZ73_RS05025	COG0583	DNA-binding transcription factor activity
GOZ73_RS05070	COG3118	belongs to the thioredoxin family
GOZ73_RS05080	COG0017	Asparaginyl-tRNA synthetase
GOZ73_RS05105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GOZ73_RS05115	COG1137	ATPase activity
GOZ73_RS05130	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GOZ73_RS05140	COG0052	Belongs to the universal ribosomal protein uS2 family
GOZ73_RS05145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GOZ73_RS05150	COG4608	Belongs to the ABC transporter superfamily
GOZ73_RS05155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GOZ73_RS05165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GOZ73_RS05175	COG0066	3-isopropylmalate dehydratase activity
GOZ73_RS05180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GOZ73_RS05185	COG0321	lipoyl(octanoyl) transferase activity
GOZ73_RS05190	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOZ73_RS05195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GOZ73_RS05205	COG1181	Belongs to the D-alanine--D-alanine ligase family
GOZ73_RS05210	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GOZ73_RS05215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GOZ73_RS05220	COG0772	Belongs to the SEDS family
GOZ73_RS05230	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GOZ73_RS05235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GOZ73_RS05240	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GOZ73_RS05245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GOZ73_RS05250	COG0768	penicillin binding
GOZ73_RS05260	COG0275	rRNA processing
GOZ73_RS05265	COG2001	Belongs to the MraZ family
GOZ73_RS05270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GOZ73_RS05275	COG2860	membrane
GOZ73_RS05285	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GOZ73_RS05290	COG0482	sulfurtransferase activity
GOZ73_RS05310	COG1028	Short-chain dehydrogenase reductase Sdr
GOZ73_RS05320	COG0488	(ABC) transporter
GOZ73_RS05330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GOZ73_RS05340	COG1253	flavin adenine dinucleotide binding
GOZ73_RS05345	COG1028	Short-chain dehydrogenase reductase Sdr
GOZ73_RS05355	COG1073	alpha beta
GOZ73_RS05365	COG0667	Aldo Keto reductase
GOZ73_RS05420	COG2267	carboxylic ester hydrolase activity
GOZ73_RS05425	COG2095	MarC family integral membrane protein
GOZ73_RS05465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GOZ73_RS05470	COG0488	(ABC) transporter
GOZ73_RS05480	COG0697	spore germination
GOZ73_RS05490	COG0215	cysteine-tRNA ligase activity
GOZ73_RS05500	COG3119	arylsulfatase activity
GOZ73_RS05510	COG0481	GTPase activity
GOZ73_RS05525	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GOZ73_RS05530	COG0085	RNA polymerase activity
GOZ73_RS05535	COG0222	ribosome binding
GOZ73_RS05540	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GOZ73_RS05545	COG0081	regulation of translation
GOZ73_RS05550	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GOZ73_RS05555	COG0250	Participates in transcription elongation, termination and antitermination
GOZ73_RS05570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GOZ73_RS05580	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GOZ73_RS05590	COG0740	serine-type endopeptidase activity
GOZ73_RS05595	COG0544	peptidyl-prolyl cis-trans isomerase activity
GOZ73_RS05610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GOZ73_RS05630	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GOZ73_RS05670	COG2226	methyltransferase
GOZ73_RS05675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GOZ73_RS05680	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GOZ73_RS05695	COG1902	pentaerythritol trinitrate reductase activity
GOZ73_RS05695	COG0446	pyridine nucleotide-disulphide oxidoreductase
GOZ73_RS05705	COG3119	arylsulfatase activity
GOZ73_RS05710	COG0514	ATP-dependent DNA helicase (RecQ)
GOZ73_RS05725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GOZ73_RS05730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GOZ73_RS05785	COG1858	cytochrome C peroxidase
GOZ73_RS05790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GOZ73_RS05795	COG0590	tRNA wobble adenosine to inosine editing
GOZ73_RS05800	COG1940	carbohydrate kinase activity
GOZ73_RS05805	COG2217	Heavy metal translocating P-type atpase
GOZ73_RS05810	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GOZ73_RS05815	COG0237	dephospho-CoA kinase activity
GOZ73_RS05845	COG1363	Peptidase, m42
GOZ73_RS05850	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GOZ73_RS05860	COG0006	proline dipeptidase activity
GOZ73_RS05865	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GOZ73_RS05890	COG5002	protein histidine kinase activity
GOZ73_RS05895	COG0745	RESPONSE REGULATOR receiver
GOZ73_RS05900	COG0129	dihydroxy-acid dehydratase activity
GOZ73_RS05925	COG1368	sulfuric ester hydrolase activity
GOZ73_RS05960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GOZ73_RS05965	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GOZ73_RS05990	COG0534	Mate efflux family protein
GOZ73_RS05995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GOZ73_RS06010	COG1876	peptidase activity
GOZ73_RS06070	COG3209	COG3209 Rhs family protein
GOZ73_RS06150	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GOZ73_RS06155	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GOZ73_RS06160	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GOZ73_RS06165	COG2205	protein histidine kinase activity
GOZ73_RS06170	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GOZ73_RS06180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOZ73_RS06200	COG0789	Transcriptional regulator
GOZ73_RS06245	COG0714	Associated with various cellular activities
GOZ73_RS06250	COG2311	Membrane
GOZ73_RS06270	COG1090	epimerase
GOZ73_RS06280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GOZ73_RS06285	COG1119	ATPase activity
GOZ73_RS06290	COG2186	Transcriptional regulator
GOZ73_RS06310	COG0148	phosphopyruvate hydratase activity
GOZ73_RS06315	COG0436	Aminotransferase
GOZ73_RS06320	COG1477	protein flavinylation
GOZ73_RS06335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GOZ73_RS06345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GOZ73_RS06365	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GOZ73_RS06375	COG1199	ATP-dependent helicase activity
GOZ73_RS06380	COG1122	ATPase activity
GOZ73_RS06405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GOZ73_RS06410	COG0598	Magnesium transport protein CorA
GOZ73_RS06415	COG0359	binds to the 23S rRNA
GOZ73_RS06420	COG0138	bifunctional purine biosynthesis protein purh
GOZ73_RS06425	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GOZ73_RS06430	COG0736	holo-[acyl-carrier-protein] synthase activity
GOZ73_RS06440	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GOZ73_RS06445	COG5632	N-Acetylmuramoyl-L-alanine amidase
GOZ73_RS06445	COG3409	Peptidoglycan-binding domain 1 protein
GOZ73_RS06450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GOZ73_RS06460	COG0437	4 iron, 4 sulfur cluster binding
GOZ73_RS06480	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GOZ73_RS06530	COG0284	orotidine-5'-phosphate decarboxylase activity
GOZ73_RS06550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GOZ73_RS06555	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GOZ73_RS06640	COG0305	Participates in initiation and elongation during chromosome replication
GOZ73_RS06770	COG2003	Belongs to the UPF0758 family
GOZ73_RS06775	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GOZ73_RS06775	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GOZ73_RS06780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GOZ73_RS06785	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GOZ73_RS06790	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GOZ73_RS06795	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GOZ73_RS06800	COG0322	excinuclease ABC activity
GOZ73_RS06805	COG0811	peptide transport
GOZ73_RS06810	COG0848	biopolymer transport protein
GOZ73_RS06820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GOZ73_RS06825	COG0483	inositol monophosphate 1-phosphatase activity
GOZ73_RS06830	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GOZ73_RS06840	COG1482	cell wall glycoprotein biosynthetic process
GOZ73_RS06850	COG1757	Na H antiporter
GOZ73_RS06855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOZ73_RS06860	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GOZ73_RS06865	COG0505	Belongs to the CarA family
GOZ73_RS06870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GOZ73_RS06885	COG0070	glutamate synthase
GOZ73_RS06885	COG0069	glutamate synthase activity
GOZ73_RS06885	COG0067	glutamate synthase
GOZ73_RS06890	COG0706	membrane insertase activity
GOZ73_RS06895	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GOZ73_RS06905	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GOZ73_RS06915	COG2755	lipolytic protein G-D-S-L family
GOZ73_RS06915	COG0657	acetylesterase activity
GOZ73_RS06925	COG0676	glucose-6-phosphate 1-epimerase activity
GOZ73_RS06930	COG0259	pyridoxamine-phosphate oxidase activity
GOZ73_RS06945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GOZ73_RS06960	COG1760	l-serine dehydratase
GOZ73_RS06965	COG0492	ferredoxin-NADP+ reductase activity
GOZ73_RS06965	COG3118	belongs to the thioredoxin family
GOZ73_RS07015	COG1408	metallophosphoesterase
GOZ73_RS07025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GOZ73_RS07030	COG0545	Peptidyl-prolyl cis-trans isomerase
GOZ73_RS07045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GOZ73_RS07055	COG0826	peptidase U32
GOZ73_RS07065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GOZ73_RS07085	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GOZ73_RS07095	COG1116	anion transmembrane transporter activity
GOZ73_RS07105	COG0529	Catalyzes the synthesis of activated sulfate
GOZ73_RS07105	COG2895	sulfate adenylyltransferase (ATP) activity
GOZ73_RS07110	COG0175	sulfate reduction
GOZ73_RS07115	COG0175	sulfate reduction
GOZ73_RS07135	COG0581	inorganic phosphate transmembrane transporter activity
GOZ73_RS07140	COG0573	inorganic phosphate transmembrane transporter activity
GOZ73_RS07150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GOZ73_RS07160	COG2017	converts alpha-aldose to the beta-anomer
GOZ73_RS07175	COG0612	Peptidase, M16
GOZ73_RS07225	COG0233	cytoplasmic translational termination
GOZ73_RS07230	COG0528	UMP kinase activity
GOZ73_RS07235	COG0668	transmembrane transport
GOZ73_RS07240	COG0450	alkyl hydroperoxide reductase
GOZ73_RS07245	COG0733	neurotransmitter:sodium symporter activity
GOZ73_RS07260	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GOZ73_RS07270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GOZ73_RS07275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GOZ73_RS07280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GOZ73_RS07300	COG0842	Transport permease protein
GOZ73_RS07305	COG0842	Transport permease protein
GOZ73_RS07310	COG1131	(ABC) transporter
GOZ73_RS07320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GOZ73_RS07325	COG1183	phosphatidylcholine synthase activity
GOZ73_RS07335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GOZ73_RS07345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GOZ73_RS07350	COG1028	Short-chain dehydrogenase reductase Sdr
GOZ73_RS07370	COG0156	8-amino-7-oxononanoate synthase activity
GOZ73_RS07390	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GOZ73_RS07395	COG0124	histidyl-tRNA synthetase
GOZ73_RS07400	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GOZ73_RS07405	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GOZ73_RS07410	COG0298	carbon dioxide binding
GOZ73_RS07440	COG0443	Heat shock 70 kDa protein
GOZ73_RS07445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GOZ73_RS07450	COG0459	protein refolding
GOZ73_RS07505	COG0632	four-way junction helicase activity
GOZ73_RS07515	COG0126	phosphoglycerate kinase activity
GOZ73_RS07525	COG1082	Xylose isomerase domain protein TIM barrel
GOZ73_RS07530	COG4991	sh3 domain protein
GOZ73_RS07530	COG3064	Membrane
GOZ73_RS07530	COG0515	serine threonine protein kinase
GOZ73_RS07535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GOZ73_RS07545	COG2271	Major facilitator Superfamily
GOZ73_RS07560	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GOZ73_RS07570	COG0037	tRNA processing
GOZ73_RS07575	COG0254	rRNA binding
GOZ73_RS07610	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GOZ73_RS07615	COG0039	L-malate dehydrogenase activity
GOZ73_RS07635	COG0778	Nitroreductase
GOZ73_RS07640	COG0564	pseudouridine synthase activity
GOZ73_RS07660	COG1126	abc transporter atp-binding protein
GOZ73_RS07665	COG0765	amino acid transport
GOZ73_RS07770	COG2856	Zn peptidase
GOZ73_RS07785	COG4085	toxin activity
GOZ73_RS07785	COG1525	nuclease
GOZ73_RS07785	COG0737	Belongs to the 5'-nucleotidase family
GOZ73_RS07890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GOZ73_RS07895	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GOZ73_RS07915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GOZ73_RS07940	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GOZ73_RS07945	COG1872	DUF167
GOZ73_RS07950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GOZ73_RS07955	COG0484	heat shock protein binding
GOZ73_RS07960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GOZ73_RS07970	COG5434	Belongs to the glycosyl hydrolase 28 family
GOZ73_RS07985	COG0277	FAD linked oxidase domain protein
GOZ73_RS08010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GOZ73_RS08015	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GOZ73_RS08025	COG0131	Imidazoleglycerol-phosphate dehydratase
GOZ73_RS08030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GOZ73_RS08035	COG0360	Binds together with S18 to 16S ribosomal RNA
GOZ73_RS08040	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GOZ73_RS08055	COG1686	Belongs to the peptidase S11 family
GOZ73_RS08060	COG0205	6-phosphofructokinase activity
GOZ73_RS08070	COG0428	transporter
GOZ73_RS08075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOZ73_RS08090	COG3977	Valine--pyruvate aminotransferase
GOZ73_RS08095	COG1561	YicC-like family, N-terminal region
GOZ73_RS08105	COG0471	metal ion transport
GOZ73_RS08105	COG3273	potassium ion transport
GOZ73_RS08110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GOZ73_RS08125	COG1575	Belongs to the MenA family. Type 1 subfamily
GOZ73_RS08130	COG0710	3-dehydroquinate dehydratase activity
GOZ73_RS08160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GOZ73_RS08160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GOZ73_RS08180	COG0202	RNA polymerase activity
GOZ73_RS08185	COG0203	ribosomal protein L17
GOZ73_RS08190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GOZ73_RS08200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GOZ73_RS08215	COG2885	chlorophyll binding
GOZ73_RS08250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GOZ73_RS08290	COG0667	Aldo Keto reductase
GOZ73_RS08295	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GOZ73_RS08310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GOZ73_RS08315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GOZ73_RS08320	COG0134	indole-3-glycerol-phosphate synthase activity
GOZ73_RS08325	COG0135	phosphoribosylanthranilate isomerase activity
GOZ73_RS08335	COG0159	tryptophan synthase activity
GOZ73_RS08350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GOZ73_RS08355	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GOZ73_RS08365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GOZ73_RS08395	COG0561	phosphatase activity
GOZ73_RS08400	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOZ73_RS08405	COG2223	nitrite transmembrane transporter activity
GOZ73_RS08430	COG1403	HNH endonuclease
GOZ73_RS08435	COG0305	Participates in initiation and elongation during chromosome replication
GOZ73_RS08545	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOZ73_RS08630	COG0863	Belongs to the N(4) N(6)-methyltransferase family
GOZ73_RS08665	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GOZ73_RS08680	COG1715	Restriction endonuclease
GOZ73_RS08700	COG2314	TM2 domain
GOZ73_RS08765	COG0556	nucleotide-excision repair
GOZ73_RS08770	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GOZ73_RS08775	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GOZ73_RS08780	COG0750	zinc metalloprotease
GOZ73_RS08795	COG1074	ATP-dependent DNA helicase activity
GOZ73_RS08805	COG0697	spore germination
GOZ73_RS08810	COG2373	Large extracellular alpha-helical protein
GOZ73_RS08815	COG1979	alcohol dehydrogenase
GOZ73_RS08825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GOZ73_RS08850	COG0372	Belongs to the citrate synthase family
GOZ73_RS08865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GOZ73_RS08875	COG1187	pseudouridine synthase activity
GOZ73_RS08885	COG0105	UTP biosynthetic process
GOZ73_RS08890	COG1215	transferase activity, transferring glycosyl groups
GOZ73_RS08895	COG0463	Glycosyl transferase, family 2
GOZ73_RS08905	COG1459	type II secretion system
GOZ73_RS08910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GOZ73_RS08915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GOZ73_RS08920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GOZ73_RS08935	COG0728	peptidoglycan biosynthetic process
GOZ73_RS08940	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GOZ73_RS08940	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GOZ73_RS08950	COG1649	PFAM Uncharacterised BCR, COG1649
GOZ73_RS08955	COG1691	(AIR) carboxylase
GOZ73_RS08960	COG0037	tRNA processing
GOZ73_RS08965	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GOZ73_RS08970	COG0142	geranyltranstransferase activity
GOZ73_RS08985	COG2151	metal-sulfur cluster biosynthetic enzyme
GOZ73_RS09005	COG1007	ATP synthesis coupled electron transport
GOZ73_RS09010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOZ73_RS09020	COG0713	ATP synthesis coupled electron transport
GOZ73_RS09025	COG0839	Belongs to the complex I subunit 6 family
GOZ73_RS09035	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GOZ73_RS09040	COG1034	ATP synthesis coupled electron transport
GOZ73_RS09045	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GOZ73_RS09050	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GOZ73_RS09055	COG0649	NAD binding
GOZ73_RS09065	COG0726	polysaccharide deacetylase
GOZ73_RS09075	COG0307	riboflavin synthase, alpha
GOZ73_RS09080	COG2264	protein methyltransferase activity
GOZ73_RS09085	COG3210	domain, Protein
GOZ73_RS09090	COG1640	4-alpha-glucanotransferase
GOZ73_RS09100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GOZ73_RS09105	COG1030	water channel activity
GOZ73_RS09110	COG0358	DNA primase activity
GOZ73_RS09115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GOZ73_RS09120	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GOZ73_RS09135	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GOZ73_RS09140	COG0793	Belongs to the peptidase S41A family
GOZ73_RS09155	COG1643	Atp-dependent helicase
GOZ73_RS09180	COG1450	Type ii and iii secretion system protein
GOZ73_RS09195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GOZ73_RS09215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GOZ73_RS09220	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GOZ73_RS09230	COG0268	Binds directly to 16S ribosomal RNA
GOZ73_RS09235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GOZ73_RS09240	COG0028	Belongs to the TPP enzyme family
GOZ73_RS09245	COG0688	phosphatidylethanolamine metabolic process
GOZ73_RS09250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GOZ73_RS09255	COG0495	leucyl-tRNA aminoacylation
GOZ73_RS09260	COG3119	arylsulfatase activity
GOZ73_RS09275	COG1166	arginine decarboxylase activity
GOZ73_RS09285	COG3250	beta-galactosidase activity
GOZ73_RS09290	COG3250	beta-galactosidase activity
GOZ73_RS09295	COG3250	beta-galactosidase activity
GOZ73_RS09300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GOZ73_RS09305	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GOZ73_RS09315	COG0205	6-phosphofructokinase activity
GOZ73_RS09365	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GOZ73_RS09370	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GOZ73_RS09375	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GOZ73_RS09385	COG4771	TonB-dependent receptor
GOZ73_RS09410	COG0402	S-adenosylhomocysteine deaminase activity
GOZ73_RS09415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GOZ73_RS09440	COG1294	oxidase, subunit
GOZ73_RS09445	COG1271	oxidase subunit
GOZ73_RS09455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GOZ73_RS09475	COG1846	Transcriptional regulator
GOZ73_RS09500	COG2949	membrane
GOZ73_RS09525	COG0514	ATP-dependent DNA helicase (RecQ)
GOZ73_RS09540	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GOZ73_RS09545	COG0045	succinate-CoA ligase (ADP-forming) activity
GOZ73_RS09550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GOZ73_RS09610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOZ73_RS09615	COG2205	protein histidine kinase activity
GOZ73_RS09630	COG0113	porphobilinogen synthase activity
GOZ73_RS09640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GOZ73_RS09660	COG0732	type I restriction modification DNA specificity domain
GOZ73_RS09675	COG0732	type I restriction modification DNA specificity domain
GOZ73_RS09685	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GOZ73_RS09710	COG4106	trans-aconitate 2-methyltransferase activity
GOZ73_RS09725	COG3475	LICD family
GOZ73_RS09730	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GOZ73_RS09740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GOZ73_RS09745	COG3475	LICD family
GOZ73_RS09750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GOZ73_RS09760	COG2166	iron-sulfur cluster assembly
GOZ73_RS09765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GOZ73_RS09775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GOZ73_RS09780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GOZ73_RS09785	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GOZ73_RS09790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GOZ73_RS09795	COG1131	(ABC) transporter
GOZ73_RS09810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GOZ73_RS09825	COG1215	transferase activity, transferring glycosyl groups
GOZ73_RS09835	COG2967	ApaG domain
GOZ73_RS09845	COG1522	sequence-specific DNA binding
GOZ73_RS09850	COG0436	Aminotransferase
GOZ73_RS09865	COG0423	glycine-tRNA ligase activity
GOZ73_RS09870	COG0656	L-ascorbic acid biosynthetic process
GOZ73_RS09885	COG2304	oxidoreductase activity
GOZ73_RS09900	COG0714	Associated with various cellular activities
GOZ73_RS09905	COG0154	amidase activity
GOZ73_RS09910	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GOZ73_RS09945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GOZ73_RS09950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GOZ73_RS09960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GOZ73_RS09960	COG2755	lipolytic protein G-D-S-L family
GOZ73_RS09980	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GOZ73_RS09990	COG0656	L-ascorbic acid biosynthetic process
GOZ73_RS10000	COG0667	Aldo Keto reductase
GOZ73_RS10005	COG1408	metallophosphoesterase
GOZ73_RS10025	COG2249	NAD(P)H dehydrogenase (quinone) activity
GOZ73_RS10030	COG0789	Transcriptional regulator
GOZ73_RS10045	COG0534	Mate efflux family protein
GOZ73_RS10065	COG1091	dTDP-4-dehydrorhamnose reductase activity
GOZ73_RS10080	COG1837	Belongs to the UPF0109 family
GOZ73_RS10085	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GOZ73_RS10090	COG0363	glucosamine-6-phosphate deaminase activity
GOZ73_RS10110	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GOZ73_RS10120	COG1741	Belongs to the pirin family
GOZ73_RS10135	COG1070	Carbohydrate kinase
GOZ73_RS10150	COG0738	Major facilitator superfamily
GOZ73_RS10165	COG1595	DNA-templated transcription, initiation
GOZ73_RS10185	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GOZ73_RS10205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GOZ73_RS10220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GOZ73_RS10225	COG2132	Multicopper oxidase
GOZ73_RS10230	COG0697	spore germination
GOZ73_RS10240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GOZ73_RS10245	COG4608	Belongs to the ABC transporter superfamily
GOZ73_RS10250	COG0444	Belongs to the ABC transporter superfamily
GOZ73_RS10255	COG4166	transmembrane transport
GOZ73_RS10260	COG4239	(ABC) transporter, permease
GOZ73_RS10265	COG0601	transmembrane transport
GOZ73_RS10285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GOZ73_RS10290	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GOZ73_RS10295	COG3738	Protein conserved in bacteria
GOZ73_RS10300	COG0151	Belongs to the GarS family
GOZ73_RS10315	COG0811	peptide transport
GOZ73_RS10325	COG0242	peptide deformylase activity
GOZ73_RS10370	COG3258	Cytochrome c
GOZ73_RS10385	COG3274	enterobacterial common antigen metabolic process
GOZ73_RS10390	COG0538	isocitrate dehydrogenase activity
GOZ73_RS10405	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GOZ73_RS10410	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GOZ73_RS10415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GOZ73_RS10425	COG0668	transmembrane transport
GOZ73_RS10430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GOZ73_RS10430	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GOZ73_RS10435	COG0805	protein transport
GOZ73_RS10440	COG1968	undecaprenyl-diphosphatase activity
GOZ73_RS10460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GOZ73_RS10470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GOZ73_RS10480	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GOZ73_RS10490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GOZ73_RS10500	COG1408	metallophosphoesterase
GOZ73_RS10525	COG4974	Belongs to the 'phage' integrase family
GOZ73_RS10545	COG1454	alcohol dehydrogenase
GOZ73_RS10550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GOZ73_RS10560	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GOZ73_RS10560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GOZ73_RS10565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GOZ73_RS10605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GOZ73_RS10615	COG4607	ABC-type enterochelin transport system periplasmic component
GOZ73_RS10620	COG4604	ABC transporter, ATP-binding protein
GOZ73_RS10625	COG4605	iron ion homeostasis
GOZ73_RS10630	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOZ73_RS10665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GOZ73_RS10665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GOZ73_RS10680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GOZ73_RS10685	COG2195	Cleaves the N-terminal amino acid of tripeptides
GOZ73_RS10705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GOZ73_RS10725	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GOZ73_RS10750	COG0519	Catalyzes the synthesis of GMP from XMP
GOZ73_RS10750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GOZ73_RS10755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GOZ73_RS10790	COG1410	methionine synthase
GOZ73_RS10790	COG0646	methionine synthase
GOZ73_RS10795	COG2966	Psort location CytoplasmicMembrane, score
GOZ73_RS10800	COG3610	response to peptide
GOZ73_RS10805	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GOZ73_RS10820	COG4974	Belongs to the 'phage' integrase family
GOZ73_RS10830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GOZ73_RS10840	COG0460	homoserine dehydrogenase
GOZ73_RS10845	COG0527	aspartate kinase activity
GOZ73_RS10855	COG5522	Integral membrane protein (intg_mem_TP0381)
GOZ73_RS10865	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GOZ73_RS10870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GOZ73_RS10875	COG1194	a g-specific adenine glycosylase
GOZ73_RS10880	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GOZ73_RS10885	COG0574	Belongs to the PEP-utilizing enzyme family
GOZ73_RS10885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GOZ73_RS10890	COG0166	Belongs to the GPI family
GOZ73_RS10900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GOZ73_RS10910	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GOZ73_RS10910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GOZ73_RS10945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GOZ73_RS10950	COG2818	Glycosylase
GOZ73_RS10970	COG3033	Beta-eliminating lyase
GOZ73_RS10985	COG0072	phenylalanine-tRNA ligase activity
GOZ73_RS10985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GOZ73_RS11005	COG0326	Molecular chaperone. Has ATPase activity
GOZ73_RS11010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GOZ73_RS11020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GOZ73_RS11025	COG1959	2 iron, 2 sulfur cluster binding
GOZ73_RS11040	COG0352	thiamine-phosphate diphosphorylase activity
GOZ73_RS11045	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GOZ73_RS11070	COG1703	isobutyryl-CoA mutase activity
GOZ73_RS11090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GOZ73_RS11100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOZ73_RS11105	COG0418	dihydroorotase activity
GOZ73_RS11120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOZ73_RS11140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GOZ73_RS11155	COG0534	Mate efflux family protein
GOZ73_RS11160	COG0489	protein tyrosine kinase activity
GOZ73_RS11170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GOZ73_RS11175	COG0339	signal peptide processing
GOZ73_RS11180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOZ73_RS11190	COG1538	Outer membrane efflux protein
GOZ73_RS11205	COG4112	unkown
GOZ73_RS11220	COG0038	chloride channel
GOZ73_RS11230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GOZ73_RS11235	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GOZ73_RS11240	COG0586	Pfam SNARE associated Golgi protein
GOZ73_RS11310	COG1012	belongs to the aldehyde dehydrogenase family
GOZ73_RS11325	COG0753	catalase activity
GOZ73_RS11335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GOZ73_RS11340	COG1592	Rubrerythrin
GOZ73_RS11345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GOZ73_RS11365	COG0489	protein tyrosine kinase activity
GOZ73_RS11375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GOZ73_RS11385	COG0438	transferase activity, transferring glycosyl groups
GOZ73_RS11395	COG0438	transferase activity, transferring glycosyl groups
GOZ73_RS11435	COG0110	maltose O-acetyltransferase activity
GOZ73_RS11445	COG1216	Glycosyl transferase, family 2
GOZ73_RS11450	COG1216	Glycosyl transferase, family 2
GOZ73_RS11490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GOZ73_RS11495	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GOZ73_RS11495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GOZ73_RS11500	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GOZ73_RS11510	COG0281	malic enzyme
GOZ73_RS11510	COG0280	phosphate acetyltransferase
GOZ73_RS11525	COG1472	Belongs to the glycosyl hydrolase 3 family
GOZ73_RS11530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GOZ73_RS11545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GOZ73_RS11560	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GOZ73_RS11565	COG1063	alcohol dehydrogenase
GOZ73_RS11580	COG0714	Associated with various cellular activities
GOZ73_RS11590	COG0193	aminoacyl-tRNA hydrolase activity
GOZ73_RS11595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GOZ73_RS11610	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GOZ73_RS11630	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GOZ73_RS11645	COG0375	protein maturation
GOZ73_RS11665	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GOZ73_RS11670	COG0778	Nitroreductase
GOZ73_RS11675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GOZ73_RS11695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GOZ73_RS11705	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GOZ73_RS11705	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GOZ73_RS11725	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GOZ73_RS11730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GOZ73_RS11735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GOZ73_RS11800	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOZ73_RS11805	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOZ73_RS11820	COG0318	PFAM AMP-dependent synthetase and ligase
GOZ73_RS11845	COG0339	signal peptide processing
GOZ73_RS11855	COG0018	arginyl-trna synthetase
GOZ73_RS11895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GOZ73_RS11900	COG0653	protein targeting
GOZ73_RS11915	COG0494	nUDIX hydrolase
GOZ73_RS12100	COG1783	phage Terminase large subunit