locus-tag	class	description
EYC51_RS00015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYC51_RS00020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYC51_RS00050	COG2003	Belongs to the UPF0758 family
EYC51_RS00100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EYC51_RS00155	COG2894	cell division
EYC51_RS00285	COG3038	cytochrome b561
EYC51_RS00295	COG2353	YceI-like domain
EYC51_RS00300	COG1393	Belongs to the ArsC family
EYC51_RS00305	COG0625	glutathione transferase activity
EYC51_RS00325	COG0084	hydrolase, TatD family'
EYC51_RS00340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYC51_RS00345	COG0354	folic acid binding
EYC51_RS00360	COG1960	acyl-CoA dehydrogenase activity
EYC51_RS00365	COG2914	Belongs to the UPF0125 (RnfH) family
EYC51_RS00370	COG2867	negative regulation of translational initiation
EYC51_RS00375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYC51_RS00380	COG1252	NADH dehydrogenase
EYC51_RS00400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYC51_RS00405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EYC51_RS00410	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYC51_RS00420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYC51_RS00425	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYC51_RS00435	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC51_RS00445	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYC51_RS00450	COG0575	Belongs to the CDS family
EYC51_RS00455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EYC51_RS00460	COG0233	cytoplasmic translational termination
EYC51_RS00465	COG0528	UMP kinase activity
EYC51_RS00470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYC51_RS00475	COG0052	Belongs to the universal ribosomal protein uS2 family
EYC51_RS00480	COG0024	Methionine aminopeptidase
EYC51_RS00485	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EYC51_RS00505	COG1286	toxin biosynthetic process
EYC51_RS00515	COG0285	dihydrofolate synthase activity
EYC51_RS00520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYC51_RS00525	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC51_RS00530	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EYC51_RS00540	COG4566	intracellular signal transduction
EYC51_RS00545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EYC51_RS00555	COG1999	signal sequence binding
EYC51_RS00575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EYC51_RS00585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC51_RS00590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_RS00595	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EYC51_RS00615	COG0183	Belongs to the thiolase family
EYC51_RS00630	COG0583	DNA-binding transcription factor activity
EYC51_RS00655	COG0194	GDP metabolic process
EYC51_RS00660	COG1758	RNA polymerase activity
EYC51_RS00665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYC51_RS00675	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EYC51_RS00680	COG0739	heme binding
EYC51_RS00685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYC51_RS00690	COG0584	glycerophosphoryl diester phosphodiesterase
EYC51_RS00695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EYC51_RS00700	COG1187	pseudouridine synthase activity
EYC51_RS00705	COG3161	chorismate lyase activity
EYC51_RS00710	COG2814	Major facilitator Superfamily
EYC51_RS00715	COG0656	L-ascorbic acid biosynthetic process
EYC51_RS00725	COG0668	transmembrane transport
EYC51_RS00730	COG0165	Argininosuccinate lyase
EYC51_RS00735	COG1846	Transcriptional regulator
EYC51_RS00735	COG1940	carbohydrate kinase activity
EYC51_RS00745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC51_RS00755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYC51_RS00765	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYC51_RS00770	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EYC51_RS00775	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EYC51_RS00780	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYC51_RS00785	COG2252	PERMEase
EYC51_RS00790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC51_RS00810	COG0488	(ABC) transporter
EYC51_RS00815	COG1619	proteins homologs of microcin C7 resistance protein MccF
EYC51_RS00825	COG1131	(ABC) transporter
EYC51_RS00830	COG0842	Transport permease protein
EYC51_RS00845	COG0697	spore germination
EYC51_RS00865	COG1666	GTP binding
EYC51_RS00870	COG0318	PFAM AMP-dependent synthetase and ligase
EYC51_RS00875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EYC51_RS00880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYC51_RS00880	COG0519	Catalyzes the synthesis of GMP from XMP
EYC51_RS00885	COG2207	Transcriptional regulator
EYC51_RS00895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC51_RS00900	COG0135	phosphoribosylanthranilate isomerase activity
EYC51_RS00905	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_RS00915	COG0101	tRNA pseudouridine synthase activity
EYC51_RS00925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYC51_RS00930	COG0473	3-isopropylmalate dehydrogenase activity
EYC51_RS00950	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EYC51_RS00955	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EYC51_RS00965	COG1295	ribonuclease BN
EYC51_RS00975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYC51_RS00980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EYC51_RS01010	COG4964	Belongs to the GSP D family
EYC51_RS01055	COG2959	enzyme of heme biosynthesis
EYC51_RS01065	COG0181	hydroxymethylbilane synthase activity
EYC51_RS01070	COG0861	Integral membrane protein TerC family
EYC51_RS01075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYC51_RS01080	COG0045	succinate-CoA ligase (ADP-forming) activity
EYC51_RS01090	COG0583	DNA-binding transcription factor activity
EYC51_RS01095	COG2137	regulation of response to DNA damage stimulus
EYC51_RS01100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EYC51_RS01115	COG0477	Major facilitator Superfamily
EYC51_RS01130	COG0318	PFAM AMP-dependent synthetase and ligase
EYC51_RS01135	COG1024	Enoyl-CoA hydratase
EYC51_RS01140	COG3162	membrane
EYC51_RS01145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYC51_RS01155	COG0540	Belongs to the ATCase OTCase family
EYC51_RS01170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYC51_RS01185	COG2070	2-Nitropropane dioxygenase
EYC51_RS01190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYC51_RS01195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYC51_RS01195	COG2111	Na H antiporter
EYC51_RS01200	COG1006	Multisubunit Na H antiporter MnhC subunit
EYC51_RS01205	COG0651	ATP synthesis coupled electron transport
EYC51_RS01215	COG2212	antiporter activity
EYC51_RS01230	COG3158	transport of potassium into the cell
EYC51_RS01235	COG0642	Histidine kinase
EYC51_RS01260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYC51_RS01265	COG4208	sulfate ABC transporter
EYC51_RS01270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYC51_RS01275	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EYC51_RS01285	COG1278	Cold shock
EYC51_RS01305	COG1648	precorrin-2 dehydrogenase activity
EYC51_RS01305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYC51_RS01310	COG2010	Cytochrome c
EYC51_RS01335	COG0535	radical SAM domain protein
EYC51_RS01340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYC51_RS01340	COG1648	precorrin-2 dehydrogenase activity
EYC51_RS01350	COG2010	Cytochrome c
EYC51_RS01355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC51_RS01365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYC51_RS01370	COG0557	exoribonuclease II activity
EYC51_RS01395	COG2375	cellular response to nickel ion
EYC51_RS01425	COG0583	DNA-binding transcription factor activity
EYC51_RS01430	COG3842	ATPase activity
EYC51_RS01440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYC51_RS01445	COG1840	ABC-type Fe3 transport system, periplasmic component
EYC51_RS01465	COG0412	Dienelactone hydrolase
EYC51_RS01470	COG3530	Putative quorum-sensing-regulated virulence factor
EYC51_RS01475	COG0625	glutathione transferase activity
EYC51_RS01480	COG1741	Belongs to the pirin family
EYC51_RS01490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC51_RS01495	COG2814	Major facilitator Superfamily
EYC51_RS01500	COG2807	transmembrane transport
EYC51_RS01505	COG2207	Transcriptional regulator
EYC51_RS01510	COG3135	benzoate transporter
EYC51_RS01545	COG0402	S-adenosylhomocysteine deaminase activity
EYC51_RS01555	COG0745	RESPONSE REGULATOR receiver
EYC51_RS01560	COG2205	protein histidine kinase activity
EYC51_RS01575	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EYC51_RS01580	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EYC51_RS01585	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EYC51_RS01590	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EYC51_RS01595	COG0330	HflC and HflK could
EYC51_RS01600	COG0330	HflC and HflK could
EYC51_RS01605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYC51_RS01610	COG1923	regulation of RNA biosynthetic process
EYC51_RS01620	COG1160	GTP binding
EYC51_RS01625	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC51_RS01630	COG2976	Protein conserved in bacteria
EYC51_RS01650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYC51_RS01655	COG0105	UTP biosynthetic process
EYC51_RS01665	COG0336	Belongs to the RNA methyltransferase TrmD family
EYC51_RS01675	COG0228	four-way junction DNA binding
EYC51_RS01680	COG0425	Belongs to the sulfur carrier protein TusA family
EYC51_RS01685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYC51_RS01700	COG2351	hydroxyisourate hydrolase activity
EYC51_RS01730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC51_RS01755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYC51_RS01760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYC51_RS01785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYC51_RS01790	COG0601	transmembrane transport
EYC51_RS01820	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EYC51_RS01825	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYC51_RS01830	COG0542	response to heat
EYC51_RS01835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYC51_RS01850	COG0348	domain, Protein
EYC51_RS01870	COG3278	Belongs to the heme-copper respiratory oxidase family
EYC51_RS01880	COG2217	Heavy metal translocating P-type atpase
EYC51_RS01885	COG2224	Isocitrate lyase
EYC51_RS01890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYC51_RS01890	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYC51_RS01910	COG1472	Belongs to the glycosyl hydrolase 3 family
EYC51_RS01915	COG0736	holo-[acyl-carrier-protein] synthase activity
EYC51_RS01925	COG2050	protein possibly involved in aromatic compounds catabolism
EYC51_RS01930	COG1024	Enoyl-CoA hydratase
EYC51_RS01935	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_RS01940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EYC51_RS01945	COG2151	metal-sulfur cluster biosynthetic enzyme
EYC51_RS01950	COG3396	Phenylacetate-CoA oxygenase
EYC51_RS01955	COG3460	Phenylacetate-CoA oxygenase
EYC51_RS01960	COG3396	Phenylacetate-CoA oxygenase
EYC51_RS01965	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EYC51_RS01970	COG0501	Belongs to the peptidase M48B family
EYC51_RS01975	COG1162	GTPase activity
EYC51_RS01985	COG0335	large ribosomal subunit rRNA binding
EYC51_RS02005	COG0450	alkyl hydroperoxide reductase
EYC51_RS02010	COG1960	acyl-CoA dehydrogenase activity
EYC51_RS02030	COG2951	lytic endotransglycosylase activity
EYC51_RS02045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYC51_RS02050	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EYC51_RS02055	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EYC51_RS02075	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYC51_RS02080	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EYC51_RS02085	COG0287	Prephenate dehydrogenase
EYC51_RS02095	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYC51_RS02110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYC51_RS02130	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYC51_RS02150	COG0753	catalase activity
EYC51_RS02160	COG4335	DNA alkylation repair
EYC51_RS02170	COG0436	Aminotransferase
EYC51_RS02180	COG0251	oxidation-reduction process
EYC51_RS02195	COG0625	glutathione transferase activity
EYC51_RS02205	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYC51_RS02210	COG0697	spore germination
EYC51_RS02220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYC51_RS02225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC51_RS02240	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EYC51_RS02245	COG1280	lysine exporter protein (LysE YggA)
EYC51_RS02265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYC51_RS02275	COG2205	protein histidine kinase activity
EYC51_RS02275	COG2198	Histidine kinase
EYC51_RS02275	COG0784	Response regulator, receiver
EYC51_RS02280	COG2046	Belongs to the sulfate adenylyltransferase family
EYC51_RS02285	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EYC51_RS02300	COG0840	transmembrane signaling receptor activity
EYC51_RS02305	COG2119	membrane
EYC51_RS02320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EYC51_RS02325	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EYC51_RS02340	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYC51_RS02345	COG2321	neutral zinc metallopeptidase
EYC51_RS02355	COG0347	Belongs to the P(II) protein family
EYC51_RS02360	COG0004	ammonium transporteR
EYC51_RS02365	COG3909	cytochrome
EYC51_RS02375	COG0625	glutathione transferase activity
EYC51_RS02390	COG0730	response to heat
EYC51_RS02395	COG0482	sulfurtransferase activity
EYC51_RS02400	COG0277	FAD linked oxidase domain protein
EYC51_RS02405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EYC51_RS02410	COG2879	small protein
EYC51_RS02415	COG1966	Carbon starvation protein
EYC51_RS02420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_RS02425	COG0765	amino acid transport
EYC51_RS02430	COG0765	amino acid transport
EYC51_RS02435	COG1126	abc transporter atp-binding protein
EYC51_RS02440	COG5285	phytanoyl-CoA dioxygenase
EYC51_RS02445	COG0662	Cupin 2, conserved barrel domain protein
EYC51_RS02455	COG0456	acetyltransferase
EYC51_RS02460	COG1846	Transcriptional regulator
EYC51_RS02470	COG0312	modulator of DNA gyrase
EYC51_RS02485	COG0308	aminopeptidase N
EYC51_RS02490	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EYC51_RS02505	COG0473	3-isopropylmalate dehydrogenase activity
EYC51_RS02510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYC51_RS02515	COG0433	COG0433 Predicted ATPase
EYC51_RS02520	COG0217	transcriptional regulatory protein
EYC51_RS02525	COG0151	Belongs to the GarS family
EYC51_RS02535	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYC51_RS02540	COG0799	negative regulation of ribosome biogenesis
EYC51_RS02545	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EYC51_RS02550	COG0424	maF-like protein
EYC51_RS02570	COG0023	Translation Initiation Factor
EYC51_RS02580	COG2084	Dehydrogenase
EYC51_RS02585	COG0625	glutathione transferase activity
EYC51_RS02590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EYC51_RS02595	COG1047	Peptidyl-prolyl cis-trans
EYC51_RS02600	COG2003	Belongs to the UPF0758 family
EYC51_RS02605	COG1737	Transcriptional regulator
EYC51_RS02610	COG0477	Major facilitator Superfamily
EYC51_RS02620	COG2271	Major facilitator Superfamily
EYC51_RS02625	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EYC51_RS02640	COG0534	Mate efflux family protein
EYC51_RS02645	COG4175	Glycine betaine
EYC51_RS02650	COG4176	ABC-type proline glycine betaine transport system permease component
EYC51_RS02660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYC51_RS02665	COG2814	Major facilitator Superfamily
EYC51_RS02670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EYC51_RS02675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYC51_RS02680	COG0495	leucyl-tRNA aminoacylation
EYC51_RS02690	COG1466	dna polymerase III delta subunit
EYC51_RS02695	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EYC51_RS02700	COG1981	membrane
EYC51_RS02715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EYC51_RS02725	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EYC51_RS02730	COG0148	phosphopyruvate hydratase activity
EYC51_RS02740	COG2814	Major facilitator Superfamily
EYC51_RS02755	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EYC51_RS02760	COG0504	CTP synthase activity
EYC51_RS02790	COG0697	spore germination
EYC51_RS02795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYC51_RS02805	COG0791	NLP P60 protein
EYC51_RS02815	COG0583	DNA-binding transcription factor activity
EYC51_RS02825	COG0583	DNA-binding transcription factor activity
EYC51_RS02835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYC51_RS02850	COG1045	serine acetyltransferase
EYC51_RS02865	COG1381	Involved in DNA repair and RecF pathway recombination
EYC51_RS02870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EYC51_RS02875	COG0571	ribonuclease III activity
EYC51_RS02890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYC51_RS02915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYC51_RS02920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYC51_RS02925	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS02930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EYC51_RS02935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYC51_RS02945	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EYC51_RS02950	COG1399	metal-binding, possibly nucleic acid-binding protein
EYC51_RS02955	COG0424	maF-like protein
EYC51_RS02965	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYC51_RS02970	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EYC51_RS02975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYC51_RS02980	COG0546	phosphoglycolate phosphatase activity
EYC51_RS02990	COG1530	ribonuclease E activity
EYC51_RS02995	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EYC51_RS03000	COG0159	tryptophan synthase activity
EYC51_RS03005	COG0133	tryptophan synthase activity
EYC51_RS03010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYC51_RS03020	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYC51_RS03025	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYC51_RS03035	COG2878	Part of a membrane complex involved in electron transport
EYC51_RS03040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYC51_RS03045	COG1129	ABC transporter
EYC51_RS03050	COG3047	cAMP biosynthetic process
EYC51_RS03075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYC51_RS03080	COG2917	probably involved in intracellular septation
EYC51_RS03090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYC51_RS03095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYC51_RS03105	COG1196	nuclear chromosome segregation
EYC51_RS03110	COG0477	Major facilitator Superfamily
EYC51_RS03115	COG1573	uracil-dna glycosylase
EYC51_RS03120	COG1214	PFAM Peptidase M22, glycoprotease
EYC51_RS03135	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EYC51_RS03140	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EYC51_RS03145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYC51_RS03150	COG0560	Phosphoserine phosphatase
EYC51_RS03165	COG1007	ATP synthesis coupled electron transport
EYC51_RS03180	COG0713	ATP synthesis coupled electron transport
EYC51_RS03190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC51_RS03195	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EYC51_RS03215	COG0649	NAD binding
EYC51_RS03220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC51_RS03225	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC51_RS03230	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC51_RS03235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EYC51_RS03250	COG0149	triose-phosphate isomerase activity
EYC51_RS03255	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS03255	COG0604	alcohol dehydrogenase
EYC51_RS03255	COG3321	synthase
EYC51_RS03270	COG1185	polyribonucleotide nucleotidyltransferase activity
EYC51_RS03275	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYC51_RS03280	COG1183	phosphatidylcholine synthase activity
EYC51_RS03285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EYC51_RS03290	COG0440	acetolactate synthase activity
EYC51_RS03295	COG0028	Belongs to the TPP enzyme family
EYC51_RS03300	COG1289	transmembrane transporter activity
EYC51_RS03305	COG3022	response to hydroperoxide
EYC51_RS03310	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS03320	COG2135	peptidase activity
EYC51_RS03380	COG3299	homolog of phage Mu protein gp47
EYC51_RS03420	COG4386	tail sheath protein
EYC51_RS03460	COG0740	serine-type endopeptidase activity
EYC51_RS03470	COG1802	Transcriptional regulator
EYC51_RS03470	COG4626	Terminase
EYC51_RS03545	COG1475	DNA binding
EYC51_RS03555	COG0582	viral genome integration into host DNA
EYC51_RS03575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYC51_RS03580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYC51_RS03585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EYC51_RS03590	COG1674	ftsk spoiiie
EYC51_RS03595	COG0492	ferredoxin-NADP+ reductase activity
EYC51_RS03615	COG0477	Major facilitator Superfamily
EYC51_RS03635	COG2272	Belongs to the type-B carboxylesterase lipase family
EYC51_RS03640	COG1960	acyl-CoA dehydrogenase activity
EYC51_RS03665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYC51_RS03685	COG2204	response regulator
EYC51_RS03725	COG4964	Belongs to the GSP D family
EYC51_RS03780	COG0612	Peptidase, M16
EYC51_RS03785	COG0484	heat shock protein binding
EYC51_RS03790	COG0443	Heat shock 70 kDa protein
EYC51_RS03795	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYC51_RS03800	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYC51_RS03805	COG1420	regulation of RNA biosynthetic process
EYC51_RS03810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYC51_RS03815	COG0497	DNA recombination
EYC51_RS03820	COG0735	belongs to the Fur family
EYC51_RS03825	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC51_RS03855	COG0477	Major facilitator Superfamily
EYC51_RS03880	COG3300	MHYT domain
EYC51_RS03880	COG5001	Diguanylate cyclase
EYC51_RS03895	COG2819	hydrolase of the alpha beta superfamily
EYC51_RS03900	COG1454	alcohol dehydrogenase
EYC51_RS03935	COG1414	Transcriptional regulator
EYC51_RS03940	COG0513	Belongs to the DEAD box helicase family
EYC51_RS03945	COG0583	DNA-binding transcription factor activity
EYC51_RS03950	COG4638	Rieske (2fe-2S)
EYC51_RS03955	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EYC51_RS03970	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYC51_RS03990	COG4569	acetaldehyde dehydrogenase (acetylating) activity
EYC51_RS03995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYC51_RS04000	COG2814	Major facilitator Superfamily
EYC51_RS04015	COG0154	amidase activity
EYC51_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS04040	COG0842	Transport permease protein
EYC51_RS04045	COG1129	ABC transporter
EYC51_RS04045	COG0842	Transport permease protein
EYC51_RS04050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_RS04060	COG3243	poly(R)-hydroxyalkanoic acid synthase
EYC51_RS04070	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYC51_RS04075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYC51_RS04085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYC51_RS04100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYC51_RS04115	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EYC51_RS04120	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EYC51_RS04140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC51_RS04255	COG0516	GMP reductase activity
EYC51_RS04255	COG0517	IMP dehydrogenase activity
EYC51_RS04265	COG1027	Aspartate ammonia-lyase
EYC51_RS04270	COG1846	Transcriptional regulator
EYC51_RS04280	COG0494	nUDIX hydrolase
EYC51_RS04285	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EYC51_RS04290	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EYC51_RS04305	COG1414	Transcriptional regulator
EYC51_RS04325	COG0513	Belongs to the DEAD box helicase family
EYC51_RS04345	COG0429	hydrolase of the alpha beta-hydrolase fold
EYC51_RS04370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC51_RS04380	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EYC51_RS04385	COG0138	bifunctional purine biosynthesis protein purh
EYC51_RS04390	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EYC51_RS04395	COG0632	four-way junction helicase activity
EYC51_RS04405	COG2255	four-way junction helicase activity
EYC51_RS04415	COG0418	dihydroorotase activity
EYC51_RS04425	COG0415	Belongs to the DNA photolyase family
EYC51_RS04465	COG2897	thiosulfate sulfurtransferase activity
EYC51_RS04480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYC51_RS04485	COG4654	Cytochrome c, class I
EYC51_RS04520	COG1177	transmembrane transport
EYC51_RS04525	COG3842	ATPase activity
EYC51_RS04530	COG1840	ABC-type Fe3 transport system, periplasmic component
EYC51_RS04535	COG2084	Dehydrogenase
EYC51_RS04550	COG0494	nUDIX hydrolase
EYC51_RS04555	COG0442	prolyl-tRNA aminoacylation
EYC51_RS04560	COG0824	Thioesterase
EYC51_RS04565	COG0811	peptide transport
EYC51_RS04570	COG0848	biopolymer transport protein
EYC51_RS04580	COG0823	Involved in the tonB-independent uptake of proteins
EYC51_RS04595	COG0596	Alpha beta hydrolase
EYC51_RS04620	COG1079	Belongs to the binding-protein-dependent transport system permease family
EYC51_RS04625	COG4603	Belongs to the binding-protein-dependent transport system permease family
EYC51_RS04630	COG3845	ABC transporter
EYC51_RS04650	COG0427	acetyl-CoA hydrolase
EYC51_RS04655	COG0583	DNA-binding transcription factor activity
EYC51_RS04665	COG3634	alkyl hydroperoxide reductase activity
EYC51_RS04680	COG0697	spore germination
EYC51_RS04685	COG0175	sulfate reduction
EYC51_RS04695	COG2895	sulfate adenylyltransferase (ATP) activity
EYC51_RS04705	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_RS04710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC51_RS04715	COG5383	Protein conserved in bacteria
EYC51_RS04725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EYC51_RS04740	COG0583	DNA-binding transcription factor activity
EYC51_RS04745	COG1741	Belongs to the pirin family
EYC51_RS04750	COG3706	GGDEF domain
EYC51_RS04755	COG0154	amidase activity
EYC51_RS04760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYC51_RS04770	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EYC51_RS04775	COG0284	orotidine-5'-phosphate decarboxylase activity
EYC51_RS04790	COG1414	Transcriptional regulator
EYC51_RS04800	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EYC51_RS04810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYC51_RS04815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EYC51_RS04840	COG0742	ribosomal rna small subunit methyltransferase
EYC51_RS04845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EYC51_RS04850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EYC51_RS04880	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EYC51_RS04895	COG1335	isochorismatase
EYC51_RS04900	COG2309	aminopeptidase activity
EYC51_RS04905	COG0596	Alpha beta hydrolase
EYC51_RS04910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYC51_RS04910	COG2010	Cytochrome c
EYC51_RS04915	COG2080	2 iron, 2 sulfur cluster binding
EYC51_RS04920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYC51_RS04920	COG2010	Cytochrome c
EYC51_RS04935	COG0411	ABC transporter
EYC51_RS04975	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_RS04985	COG1234	tRNA 3'-trailer cleavage
EYC51_RS04990	COG2188	Transcriptional regulator
EYC51_RS05000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC51_RS05010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYC51_RS05010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYC51_RS05015	COG3608	succinylglutamate desuccinylase aspartoacylase
EYC51_RS05015	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYC51_RS05020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_RS05045	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EYC51_RS05070	COG1335	isochorismatase
EYC51_RS05075	COG2309	aminopeptidase activity
EYC51_RS05080	COG0596	Alpha beta hydrolase
EYC51_RS05095	COG2031	fatty acid transporter
EYC51_RS05110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC51_RS05115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_RS05120	COG0328	RNA-DNA hybrid ribonuclease activity
EYC51_RS05125	COG2226	methyltransferase
EYC51_RS05130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYC51_RS05135	COG1388	LysM domain
EYC51_RS05135	COG0741	lytic transglycosylase activity
EYC51_RS05145	COG2204	response regulator
EYC51_RS05150	COG4191	Histidine kinase
EYC51_RS05155	COG1301	dicarboxylic acid transport
EYC51_RS05165	COG1054	Belongs to the UPF0176 family
EYC51_RS05185	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYC51_RS05200	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EYC51_RS05205	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EYC51_RS05220	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS05225	COG1877	trehalose-phosphatase activity
EYC51_RS05260	COG0604	alcohol dehydrogenase
EYC51_RS05270	COG1024	Enoyl-CoA hydratase
EYC51_RS05290	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EYC51_RS05330	COG1393	Belongs to the ArsC family
EYC51_RS05335	COG0431	NADPH-dependent FMN reductase
EYC51_RS05350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYC51_RS05350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYC51_RS05355	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYC51_RS05360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYC51_RS05365	COG1881	PFAM PEBP family protein
EYC51_RS05370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EYC51_RS05375	COG0739	heme binding
EYC51_RS05380	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EYC51_RS05385	COG0316	Belongs to the HesB IscA family
EYC51_RS05395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EYC51_RS05400	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EYC51_RS05405	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EYC51_RS05410	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EYC51_RS05415	COG0312	modulator of DNA gyrase
EYC51_RS05420	COG3028	Belongs to the UPF0307 family
EYC51_RS05450	COG4566	intracellular signal transduction
EYC51_RS05455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYC51_RS05495	COG0762	integral membrane protein
EYC51_RS05505	COG3133	Outer membrane lipoprotein
EYC51_RS05510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC51_RS05525	COG0439	Biotin carboxylase
EYC51_RS05530	COG0511	ligase activity, forming carbon-carbon bonds
EYC51_RS05535	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EYC51_RS05540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC51_RS05545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYC51_RS05550	COG3150	esterase
EYC51_RS05565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYC51_RS05570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYC51_RS05580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYC51_RS05595	COG1678	Uncharacterized ACR, COG1678
EYC51_RS05610	COG0352	thiamine-phosphate diphosphorylase activity
EYC51_RS05615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYC51_RS05630	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EYC51_RS05640	COG3237	CsbD-like
EYC51_RS05645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EYC51_RS05650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYC51_RS05655	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYC51_RS05660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EYC51_RS05685	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EYC51_RS05700	COG1126	abc transporter atp-binding protein
EYC51_RS05705	COG0765	amino acid transport
EYC51_RS05710	COG4597	amino acid ABC transporter
EYC51_RS05715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_RS05720	COG2884	Cell division ATP-binding protein ftsE
EYC51_RS05725	COG2177	Part of the ABC transporter FtsEX involved in
EYC51_RS05730	COG1194	a g-specific adenine glycosylase
EYC51_RS05735	COG0772	Belongs to the SEDS family
EYC51_RS05740	COG0768	penicillin binding
EYC51_RS05750	COG1792	Involved in formation and maintenance of cell shape
EYC51_RS05755	COG1077	Cell shape determining protein MreB Mrl
EYC51_RS05760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYC51_RS05765	COG0154	amidase activity
EYC51_RS05770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYC51_RS05775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EYC51_RS05780	COG0583	DNA-binding transcription factor activity
EYC51_RS05785	COG2259	Doxx family
EYC51_RS05790	COG3384	dioxygenase
EYC51_RS05815	COG3604	Transcriptional regulator
EYC51_RS05850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYC51_RS05870	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS05875	COG3046	protein related to deoxyribodipyrimidine photolyase
EYC51_RS05885	COG1090	epimerase
EYC51_RS05890	COG0786	glutamate:sodium symporter activity
EYC51_RS05895	COG0142	geranyltranstransferase activity
EYC51_RS05905	COG0494	nUDIX hydrolase
EYC51_RS05925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC51_RS05930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_RS05935	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EYC51_RS05955	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EYC51_RS05960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EYC51_RS05970	COG0477	Major facilitator Superfamily
EYC51_RS05985	COG4206	TonB-dependent receptor
EYC51_RS05990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYC51_RS06005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EYC51_RS06010	COG2022	thiamine diphosphate biosynthetic process
EYC51_RS06015	COG0351	phosphomethylpyrimidine kinase
EYC51_RS06020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYC51_RS06025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYC51_RS06030	COG1538	Outer membrane efflux protein
EYC51_RS06035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EYC51_RS06045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYC51_RS06060	COG2226	methyltransferase
EYC51_RS06065	COG0745	RESPONSE REGULATOR receiver
EYC51_RS06080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EYC51_RS06085	COG1984	allophanate hydrolase subunit 2
EYC51_RS06090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYC51_RS06095	COG1238	metal cluster binding
EYC51_RS06120	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EYC51_RS06125	COG4988	ABC transporter
EYC51_RS06135	COG1294	oxidase, subunit
EYC51_RS06140	COG1271	oxidase subunit
EYC51_RS06155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EYC51_RS06170	COG1137	ATPase activity
EYC51_RS06180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC51_RS06185	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EYC51_RS06190	COG1660	Displays ATPase and GTPase activities
EYC51_RS06200	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EYC51_RS06205	COG0792	nuclease activity
EYC51_RS06210	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EYC51_RS06225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYC51_RS06235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYC51_RS06240	COG0793	Belongs to the peptidase S41A family
EYC51_RS06245	COG4942	peptidase
EYC51_RS06250	COG0588	phosphoglycerate mutase activity
EYC51_RS06255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYC51_RS06265	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EYC51_RS06270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EYC51_RS06275	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_RS06280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EYC51_RS06285	COG1040	competence protein
EYC51_RS06290	COG2226	methyltransferase
EYC51_RS06300	COG2204	response regulator
EYC51_RS06320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYC51_RS06330	COG3473	Maleate cis-trans isomerase
EYC51_RS06345	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EYC51_RS06400	COG0482	sulfurtransferase activity
EYC51_RS06405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EYC51_RS06415	COG1086	Polysaccharide biosynthesis protein
EYC51_RS06440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC51_RS06465	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EYC51_RS06480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EYC51_RS06490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EYC51_RS06495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EYC51_RS06500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYC51_RS06515	COG0356	it plays a direct role in the translocation of protons across the membrane
EYC51_RS06525	COG1024	Enoyl-CoA hydratase
EYC51_RS06540	COG0037	tRNA processing
EYC51_RS06545	COG0163	prenyltransferase activity
EYC51_RS06550	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYC51_RS06555	COG2890	protein-(glutamine-N5) methyltransferase activity
EYC51_RS06575	COG0582	viral genome integration into host DNA
EYC51_RS06645	COG2948	multi-organism process
EYC51_RS06650	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EYC51_RS06680	COG4980	gas vesicle protein
EYC51_RS06680	COG1674	ftsk spoiiie
EYC51_RS06750	COG2135	peptidase activity
EYC51_RS06780	COG2003	Belongs to the UPF0758 family
EYC51_RS06805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYC51_RS06810	COG2264	protein methyltransferase activity
EYC51_RS06825	COG3180	Ammonia monooxygenase
EYC51_RS06845	COG5002	protein histidine kinase activity
EYC51_RS06860	COG0477	Major facilitator Superfamily
EYC51_RS06865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC51_RS06870	COG3383	formate dehydrogenase (NAD+) activity
EYC51_RS06870	COG0243	molybdopterin cofactor binding
EYC51_RS06875	COG0243	molybdopterin cofactor binding
EYC51_RS06875	COG3383	formate dehydrogenase (NAD+) activity
EYC51_RS06880	COG0437	4 iron, 4 sulfur cluster binding
EYC51_RS06885	COG2864	formate dehydrogenase
EYC51_RS06895	COG1921	L-seryl-tRNASec selenium transferase activity
EYC51_RS06900	COG3276	selenocysteine insertion sequence binding
EYC51_RS06915	COG4771	TonB-dependent receptor
EYC51_RS06925	COG0709	Synthesizes selenophosphate from selenide and ATP
EYC51_RS06930	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EYC51_RS06935	COG0348	domain, Protein
EYC51_RS06935	COG3901	Regulator of nitric oxide reductase transcription
EYC51_RS06940	COG4263	nitrous-oxide reductase activity
EYC51_RS06955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EYC51_RS06970	COG0166	Belongs to the GPI family
EYC51_RS06990	COG1215	transferase activity, transferring glycosyl groups
EYC51_RS07025	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYC51_RS07060	COG0156	8-amino-7-oxononanoate synthase activity
EYC51_RS07065	COG3321	synthase
EYC51_RS07065	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS07065	COG0604	alcohol dehydrogenase
EYC51_RS07070	COG2233	PERMEase
EYC51_RS07075	COG0697	spore germination
EYC51_RS07080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC51_RS07085	COG0697	spore germination
EYC51_RS07105	COG2885	chlorophyll binding
EYC51_RS07205	COG0183	Belongs to the thiolase family
EYC51_RS07210	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC51_RS07210	COG1024	Enoyl-CoA hydratase
EYC51_RS07220	COG2059	Chromate
EYC51_RS07225	COG1127	ABC transporter
EYC51_RS07230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYC51_RS07235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYC51_RS07250	COG1131	(ABC) transporter
EYC51_RS07255	COG0842	Transport permease protein
EYC51_RS07265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYC51_RS07275	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EYC51_RS07280	COG0131	Imidazoleglycerol-phosphate dehydratase
EYC51_RS07290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EYC51_RS07295	COG0107	imidazoleglycerol-phosphate synthase activity
EYC51_RS07305	COG0140	phosphoribosyl-ATP diphosphatase activity
EYC51_RS07310	COG0537	adenosine 5'-monophosphoramidase activity
EYC51_RS07315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYC51_RS07320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYC51_RS07330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYC51_RS07340	COG1970	mechanosensitive ion channel activity
EYC51_RS07345	COG0723	plastoquinol--plastocyanin reductase activity
EYC51_RS07350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYC51_RS07355	COG2857	Cytochrome c1
EYC51_RS07360	COG0625	glutathione transferase activity
EYC51_RS07365	COG2969	positive regulation of protein catabolic process
EYC51_RS07370	COG4208	sulfate ABC transporter
EYC51_RS07375	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYC51_RS07380	COG4150	thiosulfate binding
EYC51_RS07400	COG1522	sequence-specific DNA binding
EYC51_RS07405	COG3483	tryptophan 2,3-dioxygenase activity
EYC51_RS07420	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EYC51_RS07425	COG0656	L-ascorbic acid biosynthetic process
EYC51_RS07435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYC51_RS07440	COG3706	GGDEF domain
EYC51_RS07445	COG2226	methyltransferase
EYC51_RS07455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC51_RS07470	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EYC51_RS07475	COG0583	DNA-binding transcription factor activity
EYC51_RS07480	COG0477	Major facilitator Superfamily
EYC51_RS07485	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS07490	COG1335	isochorismatase
EYC51_RS07510	COG2823	Periplasmic or secreted lipoprotein
EYC51_RS07520	COG3284	Transcriptional regulator
EYC51_RS07535	COG1522	sequence-specific DNA binding
EYC51_RS07545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EYC51_RS07565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYC51_RS07595	COG1612	heme a metabolic process
EYC51_RS07600	COG0109	protoheme IX farnesyltransferase activity
EYC51_RS07640	COG3568	Endonuclease Exonuclease Phosphatase
EYC51_RS07645	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYC51_RS07670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC51_RS07680	COG1228	amidohydrolase
EYC51_RS07690	COG2986	histidine ammonia-lyase
EYC51_RS07695	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EYC51_RS07740	COG0625	glutathione transferase activity
EYC51_RS07765	COG1448	Aminotransferase
EYC51_RS07770	COG2365	Tyrosine phosphatase family
EYC51_RS07775	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EYC51_RS07795	COG2423	ornithine cyclodeaminase activity
EYC51_RS07845	COG3069	C4-dicarboxylate transmembrane transporter activity
EYC51_RS07855	COG1802	Transcriptional regulator
EYC51_RS07870	COG2814	Major facilitator Superfamily
EYC51_RS07880	COG2814	Major facilitator Superfamily
EYC51_RS07890	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EYC51_RS07895	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EYC51_RS07900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYC51_RS07920	COG5002	protein histidine kinase activity
EYC51_RS07920	COG5001	Diguanylate cyclase
EYC51_RS07925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYC51_RS07930	COG1333	cytochrome c biogenesis protein
EYC51_RS07940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EYC51_RS07945	COG0113	porphobilinogen synthase activity
EYC51_RS07950	COG4232	protein-disulfide reductase activity
EYC51_RS07970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYC51_RS07975	COG0203	ribosomal protein L17
EYC51_RS07980	COG0202	RNA polymerase activity
EYC51_RS07985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EYC51_RS07990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EYC51_RS07995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EYC51_RS08000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EYC51_RS08010	COG0201	protein transport
EYC51_RS08015	COG0200	Binds to the 23S rRNA
EYC51_RS08020	COG1841	ribosomal large subunit assembly
EYC51_RS08025	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EYC51_RS08030	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EYC51_RS08035	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EYC51_RS08040	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EYC51_RS08045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYC51_RS08050	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EYC51_RS08055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYC51_RS08060	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EYC51_RS08085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_RS08100	COG1538	Outer membrane efflux protein
EYC51_RS08120	COG0183	Belongs to the thiolase family
EYC51_RS08125	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC51_RS08125	COG1024	Enoyl-CoA hydratase
EYC51_RS08145	COG0318	PFAM AMP-dependent synthetase and ligase
EYC51_RS08150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYC51_RS08155	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYC51_RS08160	COG1648	precorrin-2 dehydrogenase activity
EYC51_RS08160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYC51_RS08175	COG1116	anion transmembrane transporter activity
EYC51_RS08195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYC51_RS08200	COG0255	Belongs to the universal ribosomal protein uL29 family
EYC51_RS08205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYC51_RS08210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EYC51_RS08215	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYC51_RS08220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EYC51_RS08225	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYC51_RS08230	COG0089	rRNA binding
EYC51_RS08235	COG0088	Forms part of the polypeptide exit tunnel
EYC51_RS08240	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EYC51_RS08245	COG4175	Glycine betaine
EYC51_RS08255	COG0051	transcription antitermination factor activity, RNA binding
EYC51_RS08260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EYC51_RS08265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYC51_RS08270	COG0049	tRNA binding
EYC51_RS08275	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYC51_RS08280	COG0745	RESPONSE REGULATOR receiver
EYC51_RS08290	COG0642	Histidine kinase
EYC51_RS08305	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EYC51_RS08315	COG0085	RNA polymerase activity
EYC51_RS08320	COG0222	ribosome binding
EYC51_RS08325	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYC51_RS08330	COG0081	regulation of translation
EYC51_RS08355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EYC51_RS08375	COG1475	DNA binding
EYC51_RS08380	COG1192	Involved in chromosome partitioning
EYC51_RS08385	COG0357	Ribosomal RNA small subunit methyltransferase G
EYC51_RS08390	COG0445	tRNA wobble uridine modification
EYC51_RS08395	COG0436	Aminotransferase
EYC51_RS08400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYC51_RS08405	COG3706	GGDEF domain
EYC51_RS08410	COG0688	phosphatidylethanolamine metabolic process
EYC51_RS08420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYC51_RS08460	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYC51_RS08500	COG0753	catalase activity
EYC51_RS08505	COG0706	membrane insertase activity
EYC51_RS08510	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EYC51_RS08515	COG0594	ribonuclease P activity
EYC51_RS08520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EYC51_RS08525	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYC51_RS08540	COG1187	pseudouridine synthase activity
EYC51_RS08545	COG1802	Transcriptional regulator
EYC51_RS08550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_RS08570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EYC51_RS08575	COG0583	DNA-binding transcription factor activity
EYC51_RS08585	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EYC51_RS08595	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYC51_RS08610	COG0318	PFAM AMP-dependent synthetase and ligase
EYC51_RS08620	COG0596	Alpha beta hydrolase
EYC51_RS08620	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC51_RS08625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC51_RS08640	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_RS08650	COG0697	spore germination
EYC51_RS08655	COG0583	DNA-binding transcription factor activity
EYC51_RS08665	COG3842	ATPase activity
EYC51_RS08675	COG0436	Aminotransferase
EYC51_RS08685	COG0523	cobalamin synthesis protein
EYC51_RS08700	COG0625	glutathione transferase activity
EYC51_RS08740	COG1846	Transcriptional regulator
EYC51_RS08760	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYC51_RS08765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC51_RS08770	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EYC51_RS08835	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS08845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYC51_RS08860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYC51_RS08875	COG4608	Belongs to the ABC transporter superfamily
EYC51_RS08880	COG0444	Belongs to the ABC transporter superfamily
EYC51_RS08885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYC51_RS08890	COG0601	transmembrane transport
EYC51_RS08895	COG4166	transmembrane transport
EYC51_RS08900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYC51_RS08905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYC51_RS08920	COG1464	Belongs to the NlpA lipoprotein family
EYC51_RS08925	COG1464	Belongs to the NlpA lipoprotein family
EYC51_RS08930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYC51_RS08935	COG2011	ABC-type metal ion transport system permease component
EYC51_RS08960	COG1464	Belongs to the NlpA lipoprotein family
EYC51_RS08970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYC51_RS08990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYC51_RS08995	COG0431	NADPH-dependent FMN reductase
EYC51_RS09015	COG4149	molybdate abc transporter
EYC51_RS09025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EYC51_RS09030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYC51_RS09035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYC51_RS09055	COG0028	Belongs to the TPP enzyme family
EYC51_RS09060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYC51_RS09110	COG2922	Belongs to the Smg family
EYC51_RS09115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYC51_RS09125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYC51_RS09130	COG0183	Belongs to the thiolase family
EYC51_RS09135	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EYC51_RS09140	COG1960	acyl-CoA dehydrogenase activity
EYC51_RS09160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYC51_RS09170	COG0018	arginyl-trna synthetase
EYC51_RS09200	COG1982	Orn Lys Arg decarboxylase major
EYC51_RS09205	COG0531	amino acid
EYC51_RS09210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYC51_RS09220	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EYC51_RS09225	COG0066	3-isopropylmalate dehydratase activity
EYC51_RS09230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYC51_RS09235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYC51_RS09240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EYC51_RS09245	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EYC51_RS09245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_RS09255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYC51_RS09260	COG1335	isochorismatase
EYC51_RS09265	COG0583	DNA-binding transcription factor activity
EYC51_RS09285	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EYC51_RS09290	COG1280	lysine exporter protein (LysE YggA)
EYC51_RS09295	COG0513	Belongs to the DEAD box helicase family
EYC51_RS09305	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EYC51_RS09320	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYC51_RS09370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYC51_RS09375	COG1127	ABC transporter
EYC51_RS09395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYC51_RS09400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYC51_RS09410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_RS09440	COG0583	DNA-binding transcription factor activity
EYC51_RS09475	COG2358	TRAP transporter, solute receptor (TAXI family
EYC51_RS09490	COG0252	asparaginase activity
EYC51_RS09515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYC51_RS09520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYC51_RS09525	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_RS09570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_RS09585	COG0758	DNA mediated transformation
EYC51_RS09590	COG0242	peptide deformylase activity
EYC51_RS09595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EYC51_RS09600	COG0697	spore germination
EYC51_RS09615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_RS09630	COG4336	lyase activity
EYC51_RS09635	COG0583	DNA-binding transcription factor activity
EYC51_RS09640	COG0859	PFAM glycosyl transferase family 9
EYC51_RS09650	COG1278	Cold shock
EYC51_RS09655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYC51_RS09660	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EYC51_RS09665	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYC51_RS09665	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYC51_RS09675	COG1686	Belongs to the peptidase S11 family
EYC51_RS09685	COG2921	Belongs to the UPF0250 family
EYC51_RS09690	COG0321	lipoyl(octanoyl) transferase activity
EYC51_RS09695	COG1024	Enoyl-CoA hydratase
EYC51_RS09700	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EYC51_RS09710	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EYC51_RS09755	COG0826	peptidase U32
EYC51_RS09765	COG3154	lipid carrier protein
EYC51_RS09790	COG0134	indole-3-glycerol-phosphate synthase activity
EYC51_RS09795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYC51_RS09800	COG0512	Glutamine amidotransferase of anthranilate synthase
EYC51_RS09810	COG0546	phosphoglycolate phosphatase activity
EYC51_RS09820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EYC51_RS09825	COG2967	ApaG domain
EYC51_RS09835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC51_RS09840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYC51_RS09850	COG0840	transmembrane signaling receptor activity
EYC51_RS09855	COG2382	esterase
EYC51_RS09860	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS09865	COG1535	isochorismatase
EYC51_RS09865	COG3433	isochorismatase activity
EYC51_RS09870	COG1169	isochorismate synthase
EYC51_RS09885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYC51_RS09890	COG3433	isochorismatase activity
EYC51_RS09890	COG1535	isochorismatase
EYC51_RS09895	COG1021	2,3-dihydroxybenzoate-AMP ligase
EYC51_RS09910	COG0411	ABC transporter
EYC51_RS09940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYC51_RS09955	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC51_RS09975	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EYC51_RS09980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYC51_RS09990	COG0513	Belongs to the DEAD box helicase family
EYC51_RS09995	COG2814	Major facilitator Superfamily
EYC51_RS10015	COG1253	flavin adenine dinucleotide binding
EYC51_RS10045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYC51_RS10060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYC51_RS10080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYC51_RS10085	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EYC51_RS10095	COG0583	DNA-binding transcription factor activity
EYC51_RS10100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_RS10105	COG1126	abc transporter atp-binding protein
EYC51_RS10110	COG0765	amino acid transport
EYC51_RS10115	COG0765	amino acid transport
EYC51_RS10120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYC51_RS10145	COG3391	amine dehydrogenase activity
EYC51_RS10150	COG2259	Doxx family
EYC51_RS10155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYC51_RS10180	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EYC51_RS10185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYC51_RS10190	COG0210	DNA helicase
EYC51_RS10215	COG0070	glutamate synthase
EYC51_RS10215	COG0067	glutamate synthase
EYC51_RS10215	COG0069	glutamate synthase activity
EYC51_RS10220	COG1024	Enoyl-CoA hydratase
EYC51_RS10230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EYC51_RS10235	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC51_RS10260	COG2918	glutathione biosynthetic process
EYC51_RS10270	COG2197	response regulator
EYC51_RS10275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC51_RS10285	COG2223	nitrite transmembrane transporter activity
EYC51_RS10290	COG2860	membrane
EYC51_RS10295	COG1346	cytolysis
EYC51_RS10305	COG0251	oxidation-reduction process
EYC51_RS10310	COG0251	oxidation-reduction process
EYC51_RS10325	COG0745	RESPONSE REGULATOR receiver
EYC51_RS10335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYC51_RS10350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYC51_RS10365	COG2096	Adenosyltransferase
EYC51_RS10380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EYC51_RS10385	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EYC51_RS10395	COG0523	cobalamin synthesis protein
EYC51_RS10400	COG0735	belongs to the Fur family
EYC51_RS10410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYC51_RS10420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EYC51_RS10430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EYC51_RS10435	COG1560	Kdo2-lipid A biosynthetic process
EYC51_RS10445	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYC51_RS10450	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EYC51_RS10455	COG1950	PFAM Membrane protein of
EYC51_RS10460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYC51_RS10475	COG0617	tRNA 3'-terminal CCA addition
EYC51_RS10490	COG0275	rRNA processing
EYC51_RS10495	COG0730	response to heat
EYC51_RS10500	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EYC51_RS10505	COG0129	dihydroxy-acid dehydratase activity
EYC51_RS10510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EYC51_RS10515	COG0628	permease
EYC51_RS10545	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EYC51_RS10560	COG0210	DNA helicase
EYC51_RS10570	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EYC51_RS10585	COG3685	Protein conserved in bacteria
EYC51_RS10605	COG0277	FAD linked oxidase domain protein
EYC51_RS10610	COG1304	FMN binding
EYC51_RS10615	COG2186	Transcriptional regulator
EYC51_RS10630	COG2188	Transcriptional regulator
EYC51_RS10635	COG1522	sequence-specific DNA binding
EYC51_RS10645	COG1113	amino acid transport
EYC51_RS10655	COG1349	DNA-binding transcription factor activity
EYC51_RS10675	COG0395	ABC-type sugar transport system, permease component
EYC51_RS10685	COG0861	Integral membrane protein TerC family
EYC51_RS10690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYC51_RS10700	COG1671	Belongs to the UPF0178 family
EYC51_RS10710	COG1418	mRNA catabolic process
EYC51_RS10720	COG4948	Mandelate Racemase Muconate Lactonizing
EYC51_RS10735	COG0154	amidase activity
EYC51_RS10745	COG0583	DNA-binding transcription factor activity
EYC51_RS10770	COG0326	Molecular chaperone. Has ATPase activity
EYC51_RS10775	COG4774	siderophore transport
EYC51_RS10780	COG3128	pkhd-type hydroxylase
EYC51_RS10790	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYC51_RS10805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYC51_RS10810	COG1652	LysM domain
EYC51_RS10825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EYC51_RS10845	COG0387	Pfam Sodium calcium exchanger
EYC51_RS10860	COG0477	Major facilitator Superfamily
EYC51_RS10865	COG0235	Class ii aldolase
EYC51_RS10880	COG3391	amine dehydrogenase activity
EYC51_RS10885	COG0590	tRNA wobble adenosine to inosine editing
EYC51_RS10890	COG3257	ureidoglycine aminohydrolase activity
EYC51_RS10895	COG0583	DNA-binding transcription factor activity
EYC51_RS10900	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EYC51_RS10905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYC51_RS10905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYC51_RS10915	COG0489	protein tyrosine kinase activity
EYC51_RS10940	COG2081	HI0933 family
EYC51_RS10945	COG0509	glycine decarboxylation via glycine cleavage system
EYC51_RS10955	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EYC51_RS10960	COG1765	OsmC-like protein
EYC51_RS10965	COG3278	Belongs to the heme-copper respiratory oxidase family
EYC51_RS11000	COG0469	pyruvate kinase activity
EYC51_RS11005	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EYC51_RS11015	COG2084	Dehydrogenase
EYC51_RS11020	COG3622	Belongs to the hyi family
EYC51_RS11025	COG3960	tartronate-semialdehyde synthase activity
EYC51_RS11030	COG0583	DNA-binding transcription factor activity
EYC51_RS11040	COG2233	PERMEase
EYC51_RS11045	COG1942	4-Oxalocrotonate Tautomerase
EYC51_RS11055	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EYC51_RS11060	COG3648	Uricase
EYC51_RS11060	COG3195	allantoin biosynthetic process
EYC51_RS11070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC51_RS11075	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYC51_RS11090	COG0438	transferase activity, transferring glycosyl groups
EYC51_RS11100	COG0438	transferase activity, transferring glycosyl groups
EYC51_RS11105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYC51_RS11110	COG0277	FAD linked oxidase domain protein
EYC51_RS11120	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYC51_RS11125	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EYC51_RS11135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC51_RS11145	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYC51_RS11155	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EYC51_RS11170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYC51_RS11175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EYC51_RS11180	COG0193	aminoacyl-tRNA hydrolase activity
EYC51_RS11190	COG0012	GTP binding
EYC51_RS11200	COG0288	reversible hydration of carbon dioxide
EYC51_RS11205	COG0583	DNA-binding transcription factor activity
EYC51_RS11215	COG4133	protoheme IX ABC transporter activity
EYC51_RS11220	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYC51_RS11235	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EYC51_RS11245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC51_RS11250	COG3088	subunit of a heme lyase
EYC51_RS11255	COG4235	cytochrome complex assembly
EYC51_RS11260	COG0785	Cytochrome C biogenesis protein
EYC51_RS11270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYC51_RS11270	COG2169	Transcriptional regulator
EYC51_RS11290	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYC51_RS11300	COG0411	ABC transporter
EYC51_RS11310	COG1858	cytochrome C peroxidase
EYC51_RS11315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYC51_RS11325	COG1959	2 iron, 2 sulfur cluster binding
EYC51_RS11330	COG2346	COG2346, Truncated hemoglobins
EYC51_RS11375	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EYC51_RS11380	COG3383	formate dehydrogenase (NAD+) activity
EYC51_RS11395	COG1910	domain protein
EYC51_RS11400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYC51_RS11405	COG0746	molybdenum cofactor guanylyltransferase activity
EYC51_RS11410	COG0303	'Molybdopterin
EYC51_RS11415	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYC51_RS11420	COG0314	molybdopterin synthase activity
EYC51_RS11430	COG0315	cyclic pyranopterin monophosphate synthase activity
EYC51_RS11460	COG0678	peroxiredoxin activity
EYC51_RS11475	COG0697	spore germination
EYC51_RS11480	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYC51_RS11500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_RS11530	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EYC51_RS11535	COG4535	Mg2 and Co2 transporter CorC
EYC51_RS11540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EYC51_RS11545	COG1702	phosphate starvation-inducible protein PhoH
EYC51_RS11550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYC51_RS11565	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYC51_RS11570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYC51_RS11575	COG1862	Preprotein translocase
EYC51_RS11580	COG0343	queuine tRNA-ribosyltransferase activity
EYC51_RS11585	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EYC51_RS11590	COG2027	D-alanyl-D-alanine carboxypeptidase
EYC51_RS11595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EYC51_RS11605	COG4575	ribosome binding
EYC51_RS11620	COG0583	DNA-binding transcription factor activity
EYC51_RS11635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYC51_RS11650	COG0154	amidase activity
EYC51_RS11660	COG0477	Major facilitator Superfamily
EYC51_RS11670	COG0346	lactoylglutathione lyase activity
EYC51_RS11675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EYC51_RS11685	COG0436	Aminotransferase
EYC51_RS11695	COG0280	phosphate acetyltransferase
EYC51_RS11695	COG0281	malic enzyme
EYC51_RS11705	COG2732	(Barnase) inhibitor
EYC51_RS11710	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYC51_RS11715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYC51_RS11720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYC51_RS11745	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYC51_RS11755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EYC51_RS11760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EYC51_RS11765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EYC51_RS11770	COG0009	L-threonylcarbamoyladenylate synthase
EYC51_RS11780	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_RS11780	COG2030	dehydratase
EYC51_RS11785	COG1960	acyl-CoA dehydrogenase activity
EYC51_RS11795	COG0405	Gamma-glutamyltransferase
EYC51_RS11805	COG0579	oxidoreductase
EYC51_RS11810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYC51_RS11815	COG0259	pyridoxamine-phosphate oxidase activity
EYC51_RS11825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYC51_RS11840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYC51_RS11845	COG1215	transferase activity, transferring glycosyl groups
EYC51_RS11855	COG0488	(ABC) transporter
EYC51_RS11875	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EYC51_RS11880	COG2894	cell division
EYC51_RS11885	COG0850	regulation of cytokinetic process
EYC51_RS11890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYC51_RS11895	COG1271	oxidase subunit
EYC51_RS11900	COG1294	oxidase, subunit
EYC51_RS11905	COG0038	chloride channel
EYC51_RS11915	COG0514	ATP-dependent DNA helicase (RecQ)
EYC51_RS11920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYC51_RS11925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYC51_RS11930	COG0633	Ferredoxin
EYC51_RS11935	COG0488	(ABC) transporter
EYC51_RS11945	COG2001	Belongs to the MraZ family
EYC51_RS11950	COG0275	rRNA processing
EYC51_RS11955	COG3116	cell division
EYC51_RS11965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EYC51_RS11970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC51_RS11975	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EYC51_RS11985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYC51_RS11990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYC51_RS11995	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYC51_RS12000	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYC51_RS12015	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EYC51_RS12025	COG1196	nuclear chromosome segregation
EYC51_RS12025	COG0739	heme binding
EYC51_RS12025	COG0741	lytic transglycosylase activity
EYC51_RS12030	COG0653	protein targeting
EYC51_RS12040	COG2239	Acts as a magnesium transporter
EYC51_RS12050	COG1473	amidohydrolase
EYC51_RS12055	COG0318	PFAM AMP-dependent synthetase and ligase
EYC51_RS12065	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EYC51_RS12065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC51_RS12080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYC51_RS12085	COG2011	ABC-type metal ion transport system permease component
EYC51_RS12095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_RS12105	COG0765	amino acid transport
EYC51_RS12110	COG1126	abc transporter atp-binding protein
EYC51_RS12130	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EYC51_RS12135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYC51_RS12140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYC51_RS12145	COG0700	Nucleoside recognition
EYC51_RS12160	COG0204	Acyl-transferase
EYC51_RS12165	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EYC51_RS12170	COG0751	glycine-tRNA ligase activity
EYC51_RS12175	COG0752	glycyl-tRNA synthetase alpha subunit
EYC51_RS12205	COG1573	uracil-dna glycosylase
EYC51_RS12215	COG0617	tRNA 3'-terminal CCA addition
EYC51_RS12225	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYC51_RS12230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYC51_RS12235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYC51_RS12240	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EYC51_RS12245	COG0586	Pfam SNARE associated Golgi protein
EYC51_RS12250	COG1477	protein flavinylation
EYC51_RS12270	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYC51_RS12275	COG0802	atpase or kinase
EYC51_RS12285	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_RS12290	COG0281	malic enzyme
EYC51_RS12290	COG0280	phosphate acetyltransferase
EYC51_RS12295	COG0583	DNA-binding transcription factor activity
EYC51_RS12300	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_RS12305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYC51_RS12325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYC51_RS12350	COG1733	regulation of RNA biosynthetic process
EYC51_RS12355	COG2910	NAD(P)H-binding
EYC51_RS12360	COG2223	nitrite transmembrane transporter activity
EYC51_RS12370	COG4974	Belongs to the 'phage' integrase family
EYC51_RS12375	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYC51_RS12380	COG4149	molybdate abc transporter
EYC51_RS12385	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYC51_RS12400	COG1074	ATP-dependent DNA helicase activity
EYC51_RS12435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYC51_RS12440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYC51_RS12445	COG0505	Belongs to the CarA family
EYC51_RS12450	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYC51_RS12470	COG2233	PERMEase
EYC51_RS12475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYC51_RS12480	COG1534	Rna-binding protein
EYC51_RS12485	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EYC51_RS12490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYC51_RS12495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYC51_RS12500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYC51_RS12510	COG0248	Ppx GppA phosphatase
EYC51_RS12515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYC51_RS12535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYC51_RS12540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYC51_RS12590	COG1231	oxidoreductase activity
EYC51_RS12600	COG2323	membrane
EYC51_RS12610	COG1368	sulfuric ester hydrolase activity
EYC51_RS12640	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYC51_RS12645	COG3327	negative regulation of DNA-templated transcription, initiation
EYC51_RS12650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC51_RS12665	COG0009	L-threonylcarbamoyladenylate synthase
EYC51_RS12670	COG1994	Peptidase M50
EYC51_RS12675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYC51_RS12680	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EYC51_RS12685	COG1595	DNA-templated transcription, initiation
EYC51_RS12695	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EYC51_RS12705	COG0156	8-amino-7-oxononanoate synthase activity
EYC51_RS12710	COG2124	cytochrome p450
EYC51_RS12715	COG3135	benzoate transporter
EYC51_RS12720	COG2850	peptidyl-arginine hydroxylation
EYC51_RS12725	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYC51_RS12750	COG0577	efflux transmembrane transporter activity
EYC51_RS12750	COG1136	(ABC) transporter
EYC51_RS12755	COG1538	Outer membrane efflux protein
EYC51_RS12760	COG0363	glucosamine-6-phosphate deaminase activity
EYC51_RS12765	COG1132	(ABC) transporter
EYC51_RS12780	COG0583	DNA-binding transcription factor activity
EYC51_RS12785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYC51_RS12795	COG0668	transmembrane transport
EYC51_RS12840	COG0154	amidase activity
EYC51_RS12845	COG2031	fatty acid transporter
EYC51_RS12855	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EYC51_RS12860	COG0483	inositol monophosphate 1-phosphatase activity
EYC51_RS12865	COG1253	flavin adenine dinucleotide binding
EYC51_RS12870	COG1968	undecaprenyl-diphosphatase activity
EYC51_RS12890	COG0215	cysteine-tRNA ligase activity
EYC51_RS12900	COG0825	malonyl-CoA metabolic process
EYC51_RS12905	COG0037	tRNA processing
EYC51_RS12925	COG0330	HflC and HflK could
EYC51_RS12940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC51_RS12960	COG4208	sulfate ABC transporter
EYC51_RS12965	COG3842	ATPase activity
EYC51_RS12975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EYC51_RS13005	COG1304	FMN binding
EYC51_RS13010	COG0435	Glutathione S-transferase
EYC51_RS13015	COG0655	NAD(P)H dehydrogenase (quinone) activity
EYC51_RS13030	COG2094	Belongs to the DNA glycosylase MPG family
EYC51_RS13035	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EYC51_RS13040	COG2363	Small membrane protein
EYC51_RS13045	COG0598	Magnesium transport protein CorA
EYC51_RS13050	COG1960	acyl-CoA dehydrogenase activity
EYC51_RS13060	COG0747	negative chemotaxis
EYC51_RS13070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYC51_RS13085	COG3284	Transcriptional regulator
EYC51_RS13090	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_RS13095	COG1454	alcohol dehydrogenase
EYC51_RS13100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYC51_RS13140	COG3829	transcription factor binding
EYC51_RS13145	COG0477	Major facilitator Superfamily
EYC51_RS13155	COG0039	L-malate dehydrogenase activity
EYC51_RS13160	COG2188	Transcriptional regulator
EYC51_RS13165	COG2009	succinate dehydrogenase
EYC51_RS13175	COG1053	succinate dehydrogenase
EYC51_RS13180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EYC51_RS13185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EYC51_RS13190	COG0372	Belongs to the citrate synthase family
EYC51_RS13195	COG2186	Transcriptional regulator
EYC51_RS13200	COG1620	l-lactate permease
EYC51_RS13205	COG0281	malic enzyme
EYC51_RS13205	COG0280	phosphate acetyltransferase
EYC51_RS13210	COG0567	Dehydrogenase, E1 component
EYC51_RS13215	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC51_RS13220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYC51_RS13225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EYC51_RS13240	COG2183	response to ionizing radiation
EYC51_RS13245	COG1199	ATP-dependent helicase activity
EYC51_RS13250	COG0659	secondary active sulfate transmembrane transporter activity
EYC51_RS13260	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EYC51_RS13260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC51_RS13265	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYC51_RS13290	COG0564	pseudouridine synthase activity
EYC51_RS13300	COG3243	poly(R)-hydroxyalkanoic acid synthase
EYC51_RS13305	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS13310	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
EYC51_RS13335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYC51_RS13340	COG1187	pseudouridine synthase activity
EYC51_RS13345	COG0779	Required for maturation of 30S ribosomal subunits
EYC51_RS13350	COG0195	Participates in both transcription termination and antitermination
EYC51_RS13350	COG2251	uridine kinase activity
EYC51_RS13355	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYC51_RS13360	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EYC51_RS13365	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EYC51_RS13370	COG1217	gtp-binding protein TYPA
EYC51_RS13375	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYC51_RS13385	COG4160	amino acid transport
EYC51_RS13395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_RS13410	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYC51_RS13415	COG0501	Belongs to the peptidase M48B family
EYC51_RS13430	COG1722	exodeoxyribonuclease VII activity
EYC51_RS13440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYC51_RS13445	COG1469	GTP cyclohydrolase I activity
EYC51_RS13450	COG0360	Binds together with S18 to 16S ribosomal RNA
EYC51_RS13455	COG2965	DNA replication, synthesis of RNA primer
EYC51_RS13460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EYC51_RS13465	COG0359	binds to the 23S rRNA
EYC51_RS13470	COG0305	Participates in initiation and elongation during chromosome replication
EYC51_RS13480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYC51_RS13485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EYC51_RS13490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYC51_RS13500	COG0436	Aminotransferase
EYC51_RS13515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYC51_RS13520	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EYC51_RS13525	COG1562	ergosterol biosynthetic process
EYC51_RS13530	COG1562	ergosterol biosynthetic process
EYC51_RS13535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYC51_RS13540	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS13565	COG3842	ATPase activity
EYC51_RS13570	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYC51_RS13575	COG1177	transmembrane transport
EYC51_RS13580	COG1393	Belongs to the ArsC family
EYC51_RS13585	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EYC51_RS13590	COG0704	Plays a role in the regulation of phosphate uptake
EYC51_RS13595	COG2203	Gaf domain
EYC51_RS13595	COG4251	negative regulation of phosphorylation
EYC51_RS13595	COG5001	Diguanylate cyclase
EYC51_RS13595	COG3706	GGDEF domain
EYC51_RS13600	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EYC51_RS13605	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYC51_RS13605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EYC51_RS13610	COG1643	Atp-dependent helicase
EYC51_RS13620	COG0438	transferase activity, transferring glycosyl groups
EYC51_RS13625	COG0726	polysaccharide deacetylase
EYC51_RS13640	COG0297	glycogen (starch) synthase activity
EYC51_RS13645	COG0438	transferase activity, transferring glycosyl groups
EYC51_RS13665	COG1132	(ABC) transporter
EYC51_RS13720	COG2186	Transcriptional regulator
EYC51_RS13725	COG0277	FAD linked oxidase domain protein
EYC51_RS13730	COG0277	FAD linked oxidase domain protein
EYC51_RS13735	COG0247	lactate metabolic process
EYC51_RS13740	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_RS13750	COG4191	Histidine kinase
EYC51_RS13770	COG2985	domain, Protein
EYC51_RS13775	COG0076	glutamate decarboxylase activity
EYC51_RS13790	COG0628	permease
EYC51_RS13795	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYC51_RS13805	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EYC51_RS13815	COG0697	spore germination
EYC51_RS13835	COG3094	Invasion gene expression up-regulator, SirB
EYC51_RS13845	COG0640	Transcriptional regulator
EYC51_RS13860	COG0789	Transcriptional regulator
EYC51_RS13870	COG0659	secondary active sulfate transmembrane transporter activity
EYC51_RS13875	COG2314	TM2 domain
EYC51_RS13880	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EYC51_RS13885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EYC51_RS13890	COG0791	NLP P60 protein
EYC51_RS13910	COG1360	Flagellar Motor Protein
EYC51_RS13920	COG0835	chemotaxis
EYC51_RS13925	COG0840	transmembrane signaling receptor activity
EYC51_RS13930	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EYC51_RS13940	COG0745	RESPONSE REGULATOR receiver
EYC51_RS13945	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EYC51_RS13955	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYC51_RS13970	COG2747	anti-sigma28 factor FlgM
EYC51_RS13980	COG1815	bacterial-type flagellum-dependent cell motility
EYC51_RS13985	COG1558	bacterial-type flagellum-dependent cell motility
EYC51_RS13990	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYC51_RS13995	COG1749	Flagellar hook protein flgE
EYC51_RS14030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYC51_RS14035	COG0840	transmembrane signaling receptor activity
EYC51_RS14045	COG0840	transmembrane signaling receptor activity
EYC51_RS14065	COG1987	bacterial-type flagellum assembly
EYC51_RS14105	COG1157	protein secretion by the type III secretion system
EYC51_RS14120	COG1766	The M ring may be actively involved in energy transduction
EYC51_RS14125	COG1677	Flagellar hook-basal body complex protein FliE
EYC51_RS14130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYC51_RS14155	COG1334	flagellar protein FlaG
EYC51_RS14160	COG1191	sigma factor activity
EYC51_RS14220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC51_RS14240	COG2733	membrane
EYC51_RS14245	COG0840	transmembrane signaling receptor activity
EYC51_RS14250	COG0840	transmembrane signaling receptor activity
EYC51_RS14265	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_RS14275	COG2610	gluconate transmembrane transporter activity
EYC51_RS14285	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS14295	COG2824	Alkylphosphonate utilization operon protein PhnA
EYC51_RS14310	COG4771	TonB-dependent receptor
EYC51_RS14315	COG1858	cytochrome C peroxidase
EYC51_RS14325	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_RS14335	COG1113	amino acid transport
EYC51_RS14350	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYC51_RS14375	COG1278	Cold shock
EYC51_RS14380	COG0642	Histidine kinase
EYC51_RS14400	COG2863	cytochrome
EYC51_RS14405	COG3258	Cytochrome c
EYC51_RS14415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYC51_RS14440	COG0025	NhaP-type Na H and K H
EYC51_RS14455	COG1289	transmembrane transporter activity
EYC51_RS14460	COG2252	PERMEase
EYC51_RS14480	COG1999	signal sequence binding
EYC51_RS14490	COG0069	glutamate synthase activity
EYC51_RS14500	COG1846	Transcriptional regulator
EYC51_RS14510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYC51_RS14550	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS14560	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_RS14565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYC51_RS14570	COG3264	Mechanosensitive ion channel
EYC51_RS14570	COG1511	domain protein
EYC51_RS14575	COG3264	Mechanosensitive ion channel
EYC51_RS14575	COG1511	domain protein
EYC51_RS14595	COG1396	sequence-specific DNA binding
EYC51_RS14600	COG3437	response regulator, receiver
EYC51_RS14605	COG2205	protein histidine kinase activity
EYC51_RS14605	COG0784	Response regulator, receiver
EYC51_RS14605	COG2198	Histidine kinase
EYC51_RS14610	COG2239	Acts as a magnesium transporter
EYC51_RS14625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EYC51_RS14630	COG1490	D-aminoacyl-tRNA deacylase activity
EYC51_RS14635	COG2076	Multidrug Resistance protein
EYC51_RS14645	COG0456	acetyltransferase
EYC51_RS14655	COG0501	Belongs to the peptidase M48B family
EYC51_RS14785	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EYC51_RS14815	COG0740	serine-type endopeptidase activity
EYC51_RS14850	COG4386	tail sheath protein
EYC51_RS14890	COG3299	homolog of phage Mu protein gp47
EYC51_RS14910	COG0582	viral genome integration into host DNA
EYC51_RS14925	COG3179	chitinase
EYC51_RS14935	COG2135	peptidase activity
EYC51_RS14995	COG2199	diguanylate cyclase activity
EYC51_RS15010	COG1522	sequence-specific DNA binding
EYC51_RS15015	COG0626	cystathionine gamma-synthase activity
EYC51_RS15025	COG0494	nUDIX hydrolase
EYC51_RS15030	COG2832	Protein of unknown function (DUF454)
EYC51_RS15040	COG0137	argininosuccinate synthase activity
EYC51_RS15045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EYC51_RS15050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYC51_RS15070	COG1609	Transcriptional regulator
EYC51_RS15085	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EYC51_RS15095	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EYC51_RS15100	COG2205	protein histidine kinase activity
EYC51_RS15105	COG0745	RESPONSE REGULATOR receiver
EYC51_RS15110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYC51_RS15120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYC51_RS15125	COG0268	Binds directly to 16S ribosomal RNA
EYC51_RS15130	COG0728	peptidoglycan biosynthetic process
EYC51_RS15140	COG0563	adenylate kinase activity
EYC51_RS15145	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EYC51_RS15150	COG2835	tetraacyldisaccharide 4'-kinase activity
EYC51_RS15160	COG0848	biopolymer transport protein
EYC51_RS15165	COG0811	peptide transport
EYC51_RS15170	COG1570	exodeoxyribonuclease VII activity
EYC51_RS15175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYC51_RS15185	COG0183	Belongs to the thiolase family
EYC51_RS15195	COG1278	Cold shock
EYC51_RS15200	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EYC51_RS15205	COG0542	response to heat
EYC51_RS15210	COG2995	paraquat-inducible protein a
EYC51_RS15215	COG3008	intermembrane lipid transfer
EYC51_RS15235	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYC51_RS15270	COG5001	Diguanylate cyclase
EYC51_RS15270	COG4251	negative regulation of phosphorylation
EYC51_RS15270	COG3706	GGDEF domain
EYC51_RS15270	COG2203	Gaf domain
EYC51_RS15275	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EYC51_RS15280	COG0756	dUTP diphosphatase activity
EYC51_RS15290	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYC51_RS15295	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EYC51_RS15300	COG0196	riboflavin kinase activity
EYC51_RS15305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYC51_RS15310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYC51_RS15310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYC51_RS15320	COG0210	DNA helicase
EYC51_RS15345	COG0488	(ABC) transporter
EYC51_RS15350	COG2890	protein-(glutamine-N5) methyltransferase activity
EYC51_RS15355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYC51_RS15360	COG2171	N-acyltransferase activity
EYC51_RS15375	COG3273	potassium ion transport
EYC51_RS15375	COG0471	metal ion transport
EYC51_RS15425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EYC51_RS15430	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYC51_RS15435	COG0740	serine-type endopeptidase activity
EYC51_RS15445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYC51_RS15450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EYC51_RS15465	COG0556	nucleotide-excision repair
EYC51_RS15470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYC51_RS15480	COG1104	cysteine desulfurase activity
EYC51_RS15490	COG0316	Belongs to the HesB IscA family
EYC51_RS15500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EYC51_RS15505	COG4221	oxidoreductase activity
EYC51_RS15520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EYC51_RS15525	COG0697	spore germination
EYC51_RS15530	COG0385	Bile acid
EYC51_RS15540	COG2831	hemolysin activation secretion protein
EYC51_RS15570	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYC51_RS15585	COG1136	(ABC) transporter
EYC51_RS15590	COG0084	hydrolase, TatD family'
EYC51_RS15605	COG0613	PHP domain protein
EYC51_RS15615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYC51_RS15615	COG0047	phosphoribosylformylglycinamidine synthase activity
EYC51_RS15630	COG0519	Catalyzes the synthesis of GMP from XMP
EYC51_RS15630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYC51_RS15635	COG0582	viral genome integration into host DNA
EYC51_RS15795	COG1484	DNA-dependent DNA replication
EYC51_RS16040	COG3344	reverse transcriptase
EYC51_RS16050	COG3344	reverse transcriptase
EYC51_RS16055	COG0583	DNA-binding transcription factor activity
EYC51_RS16070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EYC51_RS16085	COG1960	acyl-CoA dehydrogenase activity
EYC51_RS16090	COG0523	cobalamin synthesis protein
EYC51_RS16095	COG1469	GTP cyclohydrolase I activity
EYC51_RS16100	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EYC51_RS16110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYC51_RS16115	COG0735	belongs to the Fur family
EYC51_RS16120	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYC51_RS16135	COG3852	Histidine kinase
EYC51_RS16140	COG0745	RESPONSE REGULATOR receiver
EYC51_RS16150	COG1017	nitric oxide dioxygenase activity
EYC51_RS16170	COG0583	DNA-binding transcription factor activity
EYC51_RS16175	COG2372	response to copper ion
EYC51_RS16175	COG1276	copper resistance
EYC51_RS16190	COG0740	serine-type endopeptidase activity
EYC51_RS16200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYC51_RS16205	COG0640	Transcriptional regulator
EYC51_RS16235	COG3485	protocatechuate 3,4-dioxygenase
EYC51_RS16245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EYC51_RS16250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC51_RS16260	COG3135	benzoate transporter
EYC51_RS16265	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EYC51_RS16270	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EYC51_RS16280	COG4555	ABC transporter
EYC51_RS16290	COG2197	response regulator
EYC51_RS16320	COG1846	Transcriptional regulator
EYC51_RS16325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC51_RS16330	COG2271	Major facilitator Superfamily
EYC51_RS16340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYC51_RS16350	COG0697	spore germination
EYC51_RS16375	COG3842	ATPase activity
EYC51_RS16405	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EYC51_RS16410	COG0667	Aldo Keto reductase
EYC51_RS16425	COG0582	viral genome integration into host DNA
EYC51_RS16430	COG1278	Cold shock
EYC51_RS16440	COG1272	protein, Hemolysin III
EYC51_RS16445	COG3422	double-strand break repair
EYC51_RS16455	COG0477	Major facilitator Superfamily
EYC51_RS16460	COG0154	amidase activity
EYC51_RS16475	COG3040	lipid binding
EYC51_RS16480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_RS16485	COG0765	amino acid transport
EYC51_RS16490	COG0765	amino acid transport
EYC51_RS16495	COG1126	abc transporter atp-binding protein
EYC51_RS16540	COG2871	sodium ion transport
EYC51_RS16580	COG2814	Major facilitator Superfamily
EYC51_RS16585	COG1280	lysine exporter protein (LysE YggA)
EYC51_RS16615	COG0330	HflC and HflK could
EYC51_RS16625	COG2226	methyltransferase
EYC51_RS16635	COG3042	response to heat
EYC51_RS16645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC51_RS16660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYC51_RS16665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYC51_RS16680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC51_RS16685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYC51_RS16715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EYC51_RS16720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EYC51_RS16725	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYC51_RS16730	COG0072	phenylalanine-tRNA ligase activity
EYC51_RS16730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYC51_RS16745	COG2833	Protein of unknown function (DUF455)
EYC51_RS16755	COG5265	(ABC) transporter
EYC51_RS16760	COG1959	2 iron, 2 sulfur cluster binding
EYC51_RS16765	COG0719	Fe-S assembly protein
EYC51_RS16770	COG0396	ATPase activity
EYC51_RS16775	COG0719	Fe-S assembly protein
EYC51_RS16785	COG0822	iron-sulfur transferase activity
EYC51_RS16790	COG2151	metal-sulfur cluster biosynthetic enzyme
EYC51_RS16825	COG1215	transferase activity, transferring glycosyl groups
EYC51_RS16830	COG0726	polysaccharide deacetylase
EYC51_RS16830	COG1649	PFAM Uncharacterised BCR, COG1649
EYC51_RS16835	COG0457	Tetratricopeptide repeat
EYC51_RS16935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EYC51_RS17005	COG5410	chromosome segregation
EYC51_RS17080	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYC51_RS17085	COG3657	addiction module killer protein
EYC51_RS17190	COG3949	Membrane
EYC51_RS17205	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC51_RS17220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYC51_RS17225	COG0569	domain protein
EYC51_RS17230	COG1902	pentaerythritol trinitrate reductase activity
EYC51_RS17240	COG1610	YqeY-like protein
EYC51_RS17245	COG0587	DNA-directed DNA polymerase activity
EYC51_RS17285	COG0583	DNA-binding transcription factor activity
EYC51_RS17290	COG1686	Belongs to the peptidase S11 family
EYC51_RS17305	COG1360	Flagellar Motor Protein
EYC51_RS17315	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS17325	COG4221	oxidoreductase activity
EYC51_RS17330	COG0307	riboflavin synthase, alpha
EYC51_RS17345	COG1301	dicarboxylic acid transport
EYC51_RS17350	COG4191	Histidine kinase
EYC51_RS17395	COG2233	PERMEase
EYC51_RS17405	COG1473	amidohydrolase
EYC51_RS17415	COG1846	Transcriptional regulator
EYC51_RS17420	COG2816	NAD+ diphosphatase activity
EYC51_RS17425	COG1561	YicC-like family, N-terminal region
EYC51_RS17440	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EYC51_RS17445	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EYC51_RS17450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYC51_RS17455	COG0174	glutamine synthetase
EYC51_RS17460	COG2153	protein acetylation
EYC51_RS17465	COG3842	ATPase activity
EYC51_RS17470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYC51_RS17475	COG1840	ABC-type Fe3 transport system, periplasmic component
EYC51_RS17490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYC51_RS17505	COG0783	Belongs to the Dps family
EYC51_RS17515	COG3842	ATPase activity
EYC51_RS17520	COG0395	ABC-type sugar transport system, permease component
EYC51_RS17525	COG1175	transmembrane transport
EYC51_RS17530	COG1653	transport
EYC51_RS17545	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYC51_RS17565	COG0625	glutathione transferase activity
EYC51_RS17575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYC51_RS17580	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_RS17585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYC51_RS17590	COG0114	fumarate hydratase activity
EYC51_RS17595	COG2133	pyrroloquinoline quinone binding
EYC51_RS17600	COG0589	response to stress
EYC51_RS17610	COG2807	transmembrane transport
EYC51_RS17620	COG0583	DNA-binding transcription factor activity
EYC51_RS17640	COG4974	Belongs to the 'phage' integrase family
EYC51_RS17655	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EYC51_RS17815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYC51_RS17860	COG0840	transmembrane signaling receptor activity
EYC51_RS17890	COG0697	spore germination
EYC51_RS17900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYC51_RS17990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EYC51_RS17995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYC51_RS18015	COG2003	Belongs to the UPF0758 family
EYC51_RS18125	COG2894	cell division