locus-tag	class	description
D6I95_RS00015	COG1858	cytochrome C peroxidase
D6I95_RS00040	COG1113	amino acid transport
D6I95_RS00075	COG0446	pyridine nucleotide-disulphide oxidoreductase
D6I95_RS00100	COG1278	Cold shock
D6I95_RS00105	COG0642	Histidine kinase
D6I95_RS00115	COG3278	Belongs to the heme-copper respiratory oxidase family
D6I95_RS00125	COG2863	cytochrome
D6I95_RS00130	COG3258	Cytochrome c
D6I95_RS00135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D6I95_RS00140	COG4774	siderophore transport
D6I95_RS00185	COG1289	transmembrane transporter activity
D6I95_RS00190	COG2252	PERMEase
D6I95_RS00210	COG1999	signal sequence binding
D6I95_RS00220	COG0069	glutamate synthase activity
D6I95_RS00230	COG1846	Transcriptional regulator
D6I95_RS00235	COG1058	Belongs to the CinA family
D6I95_RS00235	COG1546	Belongs to the CinA family
D6I95_RS00240	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D6I95_RS00280	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS00290	COG1012	belongs to the aldehyde dehydrogenase family
D6I95_RS00305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D6I95_RS00315	COG1511	domain protein
D6I95_RS00315	COG3264	Mechanosensitive ion channel
D6I95_RS00320	COG1196	nuclear chromosome segregation
D6I95_RS00320	COG3264	Mechanosensitive ion channel
D6I95_RS00325	COG1396	sequence-specific DNA binding
D6I95_RS00330	COG3437	response regulator, receiver
D6I95_RS00335	COG0784	Response regulator, receiver
D6I95_RS00335	COG2198	Histidine kinase
D6I95_RS00335	COG2205	protein histidine kinase activity
D6I95_RS00340	COG2239	Acts as a magnesium transporter
D6I95_RS00350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D6I95_RS00355	COG1490	D-aminoacyl-tRNA deacylase activity
D6I95_RS00370	COG0456	acetyltransferase
D6I95_RS00375	COG3012	SEC-C Motif Domain Protein
D6I95_RS00380	COG0501	Belongs to the peptidase M48B family
D6I95_RS00495	COG3772	lysozyme
D6I95_RS00540	COG2199	diguanylate cyclase activity
D6I95_RS00555	COG1522	sequence-specific DNA binding
D6I95_RS00560	COG0626	cystathionine gamma-synthase activity
D6I95_RS00570	COG0494	nUDIX hydrolase
D6I95_RS00575	COG2832	Protein of unknown function (DUF454)
D6I95_RS00585	COG0137	argininosuccinate synthase activity
D6I95_RS00595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D6I95_RS00605	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D6I95_RS00615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D6I95_RS00620	COG0268	Binds directly to 16S ribosomal RNA
D6I95_RS00625	COG0728	peptidoglycan biosynthetic process
D6I95_RS00635	COG0563	adenylate kinase activity
D6I95_RS00640	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
D6I95_RS00645	COG2835	tetraacyldisaccharide 4'-kinase activity
D6I95_RS00650	COG1663	tetraacyldisaccharide 4'-kinase activity
D6I95_RS00655	COG0848	biopolymer transport protein
D6I95_RS00660	COG0811	peptide transport
D6I95_RS00665	COG1570	exodeoxyribonuclease VII activity
D6I95_RS00670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D6I95_RS00675	COG2193	ferroxidase activity
D6I95_RS00680	COG0183	Belongs to the thiolase family
D6I95_RS00690	COG1278	Cold shock
D6I95_RS00695	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D6I95_RS00700	COG0542	response to heat
D6I95_RS00705	COG2995	paraquat-inducible protein a
D6I95_RS00710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D6I95_RS00710	COG3008	intermembrane lipid transfer
D6I95_RS00730	COG0559	Belongs to the binding-protein-dependent transport system permease family
D6I95_RS00775	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
D6I95_RS00780	COG0756	dUTP diphosphatase activity
D6I95_RS00790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D6I95_RS00795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D6I95_RS00800	COG0196	riboflavin kinase activity
D6I95_RS00805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D6I95_RS00810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D6I95_RS00810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D6I95_RS00820	COG0210	DNA helicase
D6I95_RS00845	COG0488	(ABC) transporter
D6I95_RS00850	COG2890	protein-(glutamine-N5) methyltransferase activity
D6I95_RS00855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D6I95_RS00860	COG2171	N-acyltransferase activity
D6I95_RS00865	COG2207	Transcriptional regulator
D6I95_RS00875	COG3273	potassium ion transport
D6I95_RS00875	COG0471	metal ion transport
D6I95_RS00910	COG0789	Transcriptional regulator
D6I95_RS00925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D6I95_RS00930	COG0544	peptidyl-prolyl cis-trans isomerase activity
D6I95_RS00935	COG0740	serine-type endopeptidase activity
D6I95_RS00945	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D6I95_RS00955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D6I95_RS00965	COG0556	nucleotide-excision repair
D6I95_RS00970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D6I95_RS00980	COG1104	cysteine desulfurase activity
D6I95_RS00990	COG0316	Belongs to the HesB IscA family
D6I95_RS00995	COG1803	Methylglyoxal synthase
D6I95_RS00995	COG1597	lipid kinase activity
D6I95_RS01000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D6I95_RS01005	COG4221	oxidoreductase activity
D6I95_RS01015	COG0840	transmembrane signaling receptor activity
D6I95_RS01020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D6I95_RS01025	COG0697	spore germination
D6I95_RS01030	COG0385	Bile acid
D6I95_RS01040	COG2831	hemolysin activation secretion protein
D6I95_RS01045	COG3210	domain, Protein
D6I95_RS01115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D6I95_RS01130	COG1136	(ABC) transporter
D6I95_RS01135	COG0084	hydrolase, TatD family'
D6I95_RS01150	COG0613	PHP domain protein
D6I95_RS01160	COG0047	phosphoribosylformylglycinamidine synthase activity
D6I95_RS01160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D6I95_RS01175	COG0519	Catalyzes the synthesis of GMP from XMP
D6I95_RS01175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D6I95_RS01180	COG0582	viral genome integration into host DNA
D6I95_RS01285	COG1475	DNA binding
D6I95_RS01300	COG5489	Protein of unknown function (DUF736)
D6I95_RS01350	COG1192	Involved in chromosome partitioning
D6I95_RS01395	COG2207	Transcriptional regulator
D6I95_RS01400	COG0583	DNA-binding transcription factor activity
D6I95_RS01420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D6I95_RS01430	COG1960	acyl-CoA dehydrogenase activity
D6I95_RS01445	COG2801	Transposase and inactivated derivatives
D6I95_RS01450	COG0523	cobalamin synthesis protein
D6I95_RS01455	COG1469	GTP cyclohydrolase I activity
D6I95_RS01460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D6I95_RS01465	COG2166	iron-sulfur cluster assembly
D6I95_RS01470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D6I95_RS01475	COG0735	belongs to the Fur family
D6I95_RS01480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D6I95_RS01490	COG2207	Transcriptional regulator
D6I95_RS01520	COG4774	siderophore transport
D6I95_RS01535	COG0494	nUDIX hydrolase
D6I95_RS01540	COG1942	4-Oxalocrotonate Tautomerase
D6I95_RS01555	COG2070	2-Nitropropane dioxygenase
D6I95_RS01615	COG0740	serine-type endopeptidase activity
D6I95_RS01665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D6I95_RS01675	COG1960	acyl-CoA dehydrogenase activity
D6I95_RS01695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D6I95_RS01700	COG0640	Transcriptional regulator
D6I95_RS01750	COG3485	protocatechuate 3,4-dioxygenase
D6I95_RS01760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D6I95_RS01765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D6I95_RS01775	COG3135	benzoate transporter
D6I95_RS01780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D6I95_RS01785	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D6I95_RS01795	COG4555	ABC transporter
D6I95_RS01805	COG2197	response regulator
D6I95_RS01835	COG1846	Transcriptional regulator
D6I95_RS01840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D6I95_RS01845	COG2271	Major facilitator Superfamily
D6I95_RS01855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D6I95_RS01865	COG0697	spore germination
D6I95_RS01895	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D6I95_RS01900	COG0667	Aldo Keto reductase
D6I95_RS01915	COG1272	protein, Hemolysin III
D6I95_RS01920	COG3422	double-strand break repair
D6I95_RS01930	COG0477	Major facilitator Superfamily
D6I95_RS01935	COG0154	amidase activity
D6I95_RS01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D6I95_RS01965	COG0765	amino acid transport
D6I95_RS01970	COG0765	amino acid transport
D6I95_RS01975	COG1126	abc transporter atp-binding protein
D6I95_RS02025	COG2871	sodium ion transport
D6I95_RS02060	COG2814	Major facilitator Superfamily
D6I95_RS02070	COG1280	lysine exporter protein (LysE YggA)
D6I95_RS02085	COG0330	HflC and HflK could
D6I95_RS02090	COG1585	Membrane protein implicated in regulation of membrane protease activity
D6I95_RS02100	COG3042	response to heat
D6I95_RS02110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D6I95_RS02125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D6I95_RS02130	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D6I95_RS02145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D6I95_RS02150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D6I95_RS02190	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D6I95_RS02195	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D6I95_RS02200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D6I95_RS02205	COG0072	phenylalanine-tRNA ligase activity
D6I95_RS02205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D6I95_RS02220	COG2833	Protein of unknown function (DUF455)
D6I95_RS02230	COG5265	(ABC) transporter
D6I95_RS02235	COG1959	2 iron, 2 sulfur cluster binding
D6I95_RS02240	COG0719	Fe-S assembly protein
D6I95_RS02245	COG0396	ATPase activity
D6I95_RS02250	COG0719	Fe-S assembly protein
D6I95_RS02260	COG0822	iron-sulfur transferase activity
D6I95_RS02265	COG2151	metal-sulfur cluster biosynthetic enzyme
D6I95_RS02285	COG0747	negative chemotaxis
D6I95_RS02290	COG0601	transmembrane transport
D6I95_RS02295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D6I95_RS02300	COG4172	Belongs to the ABC transporter superfamily
D6I95_RS02310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D6I95_RS02340	COG1278	Cold shock
D6I95_RS02410	COG3949	Membrane
D6I95_RS02420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D6I95_RS02435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D6I95_RS02440	COG0569	domain protein
D6I95_RS02445	COG1902	pentaerythritol trinitrate reductase activity
D6I95_RS02455	COG1610	YqeY-like protein
D6I95_RS02460	COG0587	DNA-directed DNA polymerase activity
D6I95_RS02495	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS02500	COG0583	DNA-binding transcription factor activity
D6I95_RS02505	COG1686	Belongs to the peptidase S11 family
D6I95_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS02535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D6I95_RS02540	COG4221	oxidoreductase activity
D6I95_RS02545	COG0307	riboflavin synthase, alpha
D6I95_RS02560	COG1301	dicarboxylic acid transport
D6I95_RS02565	COG4191	Histidine kinase
D6I95_RS02575	COG0583	DNA-binding transcription factor activity
D6I95_RS02580	COG1053	succinate dehydrogenase
D6I95_RS02625	COG0071	Belongs to the small heat shock protein (HSP20) family
D6I95_RS02665	COG1846	Transcriptional regulator
D6I95_RS02670	COG2816	NAD+ diphosphatase activity
D6I95_RS02680	COG1561	YicC-like family, N-terminal region
D6I95_RS02695	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D6I95_RS02700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D6I95_RS02705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D6I95_RS02710	COG0174	glutamine synthetase
D6I95_RS02715	COG2153	protein acetylation
D6I95_RS02735	COG3842	ATPase activity
D6I95_RS02740	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D6I95_RS02745	COG1840	ABC-type Fe3 transport system, periplasmic component
D6I95_RS02760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D6I95_RS02770	COG0783	Belongs to the Dps family
D6I95_RS02780	COG3842	ATPase activity
D6I95_RS02785	COG0395	ABC-type sugar transport system, permease component
D6I95_RS02790	COG1175	transmembrane transport
D6I95_RS02795	COG1653	transport
D6I95_RS02810	COG0559	Belongs to the binding-protein-dependent transport system permease family
D6I95_RS02835	COG0625	glutathione transferase activity
D6I95_RS02845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D6I95_RS02850	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS02855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D6I95_RS02860	COG0114	fumarate hydratase activity
D6I95_RS02865	COG2133	pyrroloquinoline quinone binding
D6I95_RS02870	COG0589	response to stress
D6I95_RS02880	COG2807	transmembrane transport
D6I95_RS02890	COG0583	DNA-binding transcription factor activity
D6I95_RS02910	COG4974	Belongs to the 'phage' integrase family
D6I95_RS02920	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D6I95_RS03095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D6I95_RS03135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D6I95_RS03175	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D6I95_RS03180	COG0210	DNA helicase
D6I95_RS03210	COG2003	Belongs to the UPF0758 family
D6I95_RS03275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D6I95_RS03320	COG2894	cell division
D6I95_RS03340	COG4771	TonB-dependent receptor
D6I95_RS03350	COG1858	cytochrome C peroxidase
D6I95_RS03385	COG4774	siderophore transport
D6I95_RS03450	COG1683	Conserved Protein
D6I95_RS03500	COG4608	Belongs to the ABC transporter superfamily
D6I95_RS03505	COG0444	Belongs to the ABC transporter superfamily
D6I95_RS03510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D6I95_RS03515	COG0601	transmembrane transport
D6I95_RS03520	COG0747	negative chemotaxis
D6I95_RS03525	COG0583	DNA-binding transcription factor activity
D6I95_RS03550	COG3038	cytochrome b561
D6I95_RS03560	COG2353	YceI-like domain
D6I95_RS03565	COG1393	Belongs to the ArsC family
D6I95_RS03570	COG0625	glutathione transferase activity
D6I95_RS03585	COG0084	hydrolase, TatD family'
D6I95_RS03590	COG0470	DNA polymerase III
D6I95_RS03600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D6I95_RS03605	COG0354	folic acid binding
D6I95_RS03620	COG1960	acyl-CoA dehydrogenase activity
D6I95_RS03625	COG2914	Belongs to the UPF0125 (RnfH) family
D6I95_RS03630	COG2867	negative regulation of translational initiation
D6I95_RS03635	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D6I95_RS03640	COG1252	NADH dehydrogenase
D6I95_RS03660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D6I95_RS03665	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D6I95_RS03670	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D6I95_RS03680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D6I95_RS03685	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D6I95_RS03705	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D6I95_RS03710	COG0575	Belongs to the CDS family
D6I95_RS03715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D6I95_RS03720	COG0233	cytoplasmic translational termination
D6I95_RS03725	COG0528	UMP kinase activity
D6I95_RS03730	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D6I95_RS03735	COG0052	Belongs to the universal ribosomal protein uS2 family
D6I95_RS03740	COG0024	Methionine aminopeptidase
D6I95_RS03745	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
D6I95_RS03770	COG1286	toxin biosynthetic process
D6I95_RS03780	COG0285	dihydrofolate synthase activity
D6I95_RS03785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D6I95_RS03790	COG0508	dehydrogenase complex catalyzes the overall conversion of
D6I95_RS03795	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D6I95_RS03810	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D6I95_RS03820	COG1999	signal sequence binding
D6I95_RS03825	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D6I95_RS03835	COG0640	Transcriptional regulator
D6I95_RS03850	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D6I95_RS03855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D6I95_RS03860	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D6I95_RS03865	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D6I95_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS03895	COG0183	Belongs to the thiolase family
D6I95_RS03915	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D6I95_RS03925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D6I95_RS03930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D6I95_RS03955	COG0183	Belongs to the thiolase family
D6I95_RS03995	COG0194	GDP metabolic process
D6I95_RS04000	COG1758	RNA polymerase activity
D6I95_RS04005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D6I95_RS04015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D6I95_RS04020	COG0739	heme binding
D6I95_RS04025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D6I95_RS04030	COG0584	glycerophosphoryl diester phosphodiesterase
D6I95_RS04035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D6I95_RS04040	COG1187	pseudouridine synthase activity
D6I95_RS04045	COG3161	chorismate lyase activity
D6I95_RS04050	COG2814	Major facilitator Superfamily
D6I95_RS04055	COG0656	L-ascorbic acid biosynthetic process
D6I95_RS04065	COG0668	transmembrane transport
D6I95_RS04070	COG0165	Argininosuccinate lyase
D6I95_RS04075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D6I95_RS04085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D6I95_RS04095	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D6I95_RS04100	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
D6I95_RS04105	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D6I95_RS04110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D6I95_RS04115	COG2252	PERMEase
D6I95_RS04120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D6I95_RS04140	COG0488	(ABC) transporter
D6I95_RS04145	COG1619	proteins homologs of microcin C7 resistance protein MccF
D6I95_RS04150	COG0590	tRNA wobble adenosine to inosine editing
D6I95_RS04155	COG1131	(ABC) transporter
D6I95_RS04160	COG0842	Transport permease protein
D6I95_RS04175	COG0697	spore germination
D6I95_RS04190	COG1666	GTP binding
D6I95_RS04195	COG0318	PFAM AMP-dependent synthetase and ligase
D6I95_RS04200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D6I95_RS04205	COG0519	Catalyzes the synthesis of GMP from XMP
D6I95_RS04205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D6I95_RS04210	COG2207	Transcriptional regulator
D6I95_RS04225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D6I95_RS04230	COG0135	phosphoribosylanthranilate isomerase activity
D6I95_RS04235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D6I95_RS04245	COG0101	tRNA pseudouridine synthase activity
D6I95_RS04255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D6I95_RS04260	COG0473	3-isopropylmalate dehydrogenase activity
D6I95_RS04275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D6I95_RS04285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D6I95_RS04290	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
D6I95_RS04300	COG1295	ribonuclease BN
D6I95_RS04310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D6I95_RS04345	COG4964	Belongs to the GSP D family
D6I95_RS04380	COG3712	iron ion homeostasis
D6I95_RS04385	COG1595	DNA-templated transcription, initiation
D6I95_RS04395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D6I95_RS04405	COG2959	enzyme of heme biosynthesis
D6I95_RS04415	COG0181	hydroxymethylbilane synthase activity
D6I95_RS04420	COG0861	Integral membrane protein TerC family
D6I95_RS04425	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D6I95_RS04430	COG0045	succinate-CoA ligase (ADP-forming) activity
D6I95_RS04440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D6I95_RS04445	COG0583	DNA-binding transcription factor activity
D6I95_RS04450	COG2137	regulation of response to DNA damage stimulus
D6I95_RS04470	COG0477	Major facilitator Superfamily
D6I95_RS04485	COG0318	PFAM AMP-dependent synthetase and ligase
D6I95_RS04490	COG1024	Enoyl-CoA hydratase
D6I95_RS04495	COG3162	membrane
D6I95_RS04510	COG0540	Belongs to the ATCase OTCase family
D6I95_RS04525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D6I95_RS04540	COG2070	2-Nitropropane dioxygenase
D6I95_RS04550	COG2111	Na H antiporter
D6I95_RS04550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D6I95_RS04555	COG1006	Multisubunit Na H antiporter MnhC subunit
D6I95_RS04560	COG0651	ATP synthesis coupled electron transport
D6I95_RS04570	COG2212	antiporter activity
D6I95_RS04575	COG1320	monovalent cation:proton antiporter activity
D6I95_RS04585	COG3158	transport of potassium into the cell
D6I95_RS04590	COG0642	Histidine kinase
D6I95_RS04615	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D6I95_RS04620	COG4208	sulfate ABC transporter
D6I95_RS04625	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D6I95_RS04630	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D6I95_RS04640	COG1278	Cold shock
D6I95_RS04670	COG1648	precorrin-2 dehydrogenase activity
D6I95_RS04670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D6I95_RS04675	COG2010	Cytochrome c
D6I95_RS04685	COG1522	sequence-specific DNA binding
D6I95_RS04700	COG0535	radical SAM domain protein
D6I95_RS04705	COG1648	precorrin-2 dehydrogenase activity
D6I95_RS04705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D6I95_RS04715	COG2010	Cytochrome c
D6I95_RS04720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D6I95_RS04725	COG0626	cystathionine gamma-synthase activity
D6I95_RS04730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D6I95_RS04735	COG0557	exoribonuclease II activity
D6I95_RS04760	COG2375	cellular response to nickel ion
D6I95_RS04790	COG0583	DNA-binding transcription factor activity
D6I95_RS04795	COG3842	ATPase activity
D6I95_RS04805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D6I95_RS04810	COG1840	ABC-type Fe3 transport system, periplasmic component
D6I95_RS04830	COG2807	transmembrane transport
D6I95_RS04845	COG2226	methyltransferase
D6I95_RS04850	COG4771	TonB-dependent receptor
D6I95_RS04875	COG3530	Putative quorum-sensing-regulated virulence factor
D6I95_RS04880	COG0625	glutathione transferase activity
D6I95_RS04890	COG1741	Belongs to the pirin family
D6I95_RS04900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D6I95_RS04905	COG2814	Major facilitator Superfamily
D6I95_RS04910	COG2807	transmembrane transport
D6I95_RS04915	COG2207	Transcriptional regulator
D6I95_RS04920	COG3135	benzoate transporter
D6I95_RS04945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D6I95_RS04955	COG0402	S-adenosylhomocysteine deaminase activity
D6I95_RS04965	COG0745	RESPONSE REGULATOR receiver
D6I95_RS04970	COG2205	protein histidine kinase activity
D6I95_RS04985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D6I95_RS04990	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
D6I95_RS04995	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D6I95_RS05005	COG0330	HflC and HflK could
D6I95_RS05010	COG0330	HflC and HflK could
D6I95_RS05015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D6I95_RS05020	COG1923	regulation of RNA biosynthetic process
D6I95_RS05030	COG1160	GTP binding
D6I95_RS05035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D6I95_RS05040	COG2976	Protein conserved in bacteria
D6I95_RS05045	COG0124	histidyl-tRNA synthetase
D6I95_RS05060	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D6I95_RS05065	COG0105	UTP biosynthetic process
D6I95_RS05080	COG0336	Belongs to the RNA methyltransferase TrmD family
D6I95_RS05090	COG0228	four-way junction DNA binding
D6I95_RS05095	COG0425	Belongs to the sulfur carrier protein TusA family
D6I95_RS05100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D6I95_RS05115	COG2351	hydroxyisourate hydrolase activity
D6I95_RS05145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D6I95_RS05170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D6I95_RS05175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D6I95_RS05190	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D6I95_RS05195	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D6I95_RS05200	COG0542	response to heat
D6I95_RS05205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D6I95_RS05220	COG0348	domain, Protein
D6I95_RS05240	COG3278	Belongs to the heme-copper respiratory oxidase family
D6I95_RS05250	COG2217	Heavy metal translocating P-type atpase
D6I95_RS05255	COG2224	Isocitrate lyase
D6I95_RS05260	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D6I95_RS05260	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D6I95_RS05280	COG1472	Belongs to the glycosyl hydrolase 3 family
D6I95_RS05285	COG0736	holo-[acyl-carrier-protein] synthase activity
D6I95_RS05295	COG2050	protein possibly involved in aromatic compounds catabolism
D6I95_RS05300	COG1024	Enoyl-CoA hydratase
D6I95_RS05305	COG1012	belongs to the aldehyde dehydrogenase family
D6I95_RS05310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D6I95_RS05315	COG2151	metal-sulfur cluster biosynthetic enzyme
D6I95_RS05320	COG3396	Phenylacetate-CoA oxygenase
D6I95_RS05325	COG3460	Phenylacetate-CoA oxygenase
D6I95_RS05330	COG3396	Phenylacetate-CoA oxygenase
D6I95_RS05335	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
D6I95_RS05340	COG0501	Belongs to the peptidase M48B family
D6I95_RS05345	COG1162	GTPase activity
D6I95_RS05355	COG0335	large ribosomal subunit rRNA binding
D6I95_RS05375	COG0450	alkyl hydroperoxide reductase
D6I95_RS05380	COG1960	acyl-CoA dehydrogenase activity
D6I95_RS05400	COG2951	lytic endotransglycosylase activity
D6I95_RS05415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D6I95_RS05420	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D6I95_RS05425	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D6I95_RS05445	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D6I95_RS05450	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D6I95_RS05455	COG0287	Prephenate dehydrogenase
D6I95_RS05465	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D6I95_RS05480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D6I95_RS05500	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D6I95_RS05520	COG4335	DNA alkylation repair
D6I95_RS05525	COG1846	Transcriptional regulator
D6I95_RS05530	COG0436	Aminotransferase
D6I95_RS05535	COG1309	transcriptional regulator
D6I95_RS05560	COG0625	glutathione transferase activity
D6I95_RS05635	COG4974	Belongs to the 'phage' integrase family
D6I95_RS05645	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
D6I95_RS05650	COG1280	lysine exporter protein (LysE YggA)
D6I95_RS05670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D6I95_RS05680	COG5002	protein histidine kinase activity
D6I95_RS05685	COG2046	Belongs to the sulfate adenylyltransferase family
D6I95_RS05690	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D6I95_RS05705	COG0840	transmembrane signaling receptor activity
D6I95_RS05710	COG2119	membrane
D6I95_RS05725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D6I95_RS05730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D6I95_RS05745	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D6I95_RS05750	COG2321	neutral zinc metallopeptidase
D6I95_RS05760	COG0347	Belongs to the P(II) protein family
D6I95_RS05765	COG0004	ammonium transporteR
D6I95_RS05770	COG3909	cytochrome
D6I95_RS05780	COG0625	glutathione transferase activity
D6I95_RS05785	COG0730	response to heat
D6I95_RS05790	COG0482	sulfurtransferase activity
D6I95_RS05795	COG0277	FAD linked oxidase domain protein
D6I95_RS05800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D6I95_RS05805	COG2879	small protein
D6I95_RS05810	COG1966	Carbon starvation protein
D6I95_RS05815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D6I95_RS05820	COG0765	amino acid transport
D6I95_RS05825	COG0765	amino acid transport
D6I95_RS05830	COG1126	abc transporter atp-binding protein
D6I95_RS05840	COG5285	phytanoyl-CoA dioxygenase
D6I95_RS05845	COG0662	Cupin 2, conserved barrel domain protein
D6I95_RS05855	COG0456	acetyltransferase
D6I95_RS05860	COG1846	Transcriptional regulator
D6I95_RS05870	COG0312	modulator of DNA gyrase
D6I95_RS05885	COG0308	aminopeptidase N
D6I95_RS05890	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D6I95_RS05915	COG0473	3-isopropylmalate dehydrogenase activity
D6I95_RS05925	COG0433	COG0433 Predicted ATPase
D6I95_RS05930	COG0217	transcriptional regulatory protein
D6I95_RS05935	COG0151	Belongs to the GarS family
D6I95_RS05945	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D6I95_RS05950	COG0799	negative regulation of ribosome biogenesis
D6I95_RS05955	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D6I95_RS05960	COG0424	maF-like protein
D6I95_RS05980	COG0023	Translation Initiation Factor
D6I95_RS05990	COG2084	Dehydrogenase
D6I95_RS05995	COG0625	glutathione transferase activity
D6I95_RS06000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D6I95_RS06005	COG1047	Peptidyl-prolyl cis-trans
D6I95_RS06010	COG2003	Belongs to the UPF0758 family
D6I95_RS06025	COG0534	Mate efflux family protein
D6I95_RS06030	COG4175	Glycine betaine
D6I95_RS06035	COG4176	ABC-type proline glycine betaine transport system permease component
D6I95_RS06045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D6I95_RS06050	COG2814	Major facilitator Superfamily
D6I95_RS06055	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D6I95_RS06060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D6I95_RS06065	COG2318	DinB family
D6I95_RS06075	COG0495	leucyl-tRNA aminoacylation
D6I95_RS06085	COG1466	dna polymerase III delta subunit
D6I95_RS06090	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D6I95_RS06095	COG1981	membrane
D6I95_RS06110	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D6I95_RS06120	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D6I95_RS06125	COG0148	phosphopyruvate hydratase activity
D6I95_RS06135	COG2814	Major facilitator Superfamily
D6I95_RS06150	COG2877	3-deoxy-8-phosphooctulonate synthase activity
D6I95_RS06155	COG0504	CTP synthase activity
D6I95_RS06190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D6I95_RS06200	COG0791	NLP P60 protein
D6I95_RS06210	COG0583	DNA-binding transcription factor activity
D6I95_RS06220	COG0583	DNA-binding transcription factor activity
D6I95_RS06225	COG4774	siderophore transport
D6I95_RS06235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D6I95_RS06245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D6I95_RS06250	COG1309	transcriptional regulator
D6I95_RS06260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D6I95_RS06275	COG1045	serine acetyltransferase
D6I95_RS06290	COG1381	Involved in DNA repair and RecF pathway recombination
D6I95_RS06295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D6I95_RS06300	COG0571	ribonuclease III activity
D6I95_RS06315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D6I95_RS06340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D6I95_RS06345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D6I95_RS06350	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS06355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D6I95_RS06360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D6I95_RS06370	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D6I95_RS06375	COG1399	metal-binding, possibly nucleic acid-binding protein
D6I95_RS06380	COG0424	maF-like protein
D6I95_RS06390	COG3023	N-Acetylmuramoyl-L-alanine amidase
D6I95_RS06395	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
D6I95_RS06400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D6I95_RS06405	COG0546	phosphoglycolate phosphatase activity
D6I95_RS06410	COG0564	pseudouridine synthase activity
D6I95_RS06415	COG1530	ribonuclease E activity
D6I95_RS06420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D6I95_RS06425	COG0159	tryptophan synthase activity
D6I95_RS06430	COG0133	tryptophan synthase activity
D6I95_RS06435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D6I95_RS06445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D6I95_RS06450	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D6I95_RS06460	COG2878	Part of a membrane complex involved in electron transport
D6I95_RS06465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D6I95_RS06470	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D6I95_RS06475	COG3047	cAMP biosynthetic process
D6I95_RS06500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D6I95_RS06505	COG2917	probably involved in intracellular septation
D6I95_RS06515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D6I95_RS06520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D6I95_RS06530	COG1196	nuclear chromosome segregation
D6I95_RS06540	COG1573	uracil-dna glycosylase
D6I95_RS06545	COG1214	PFAM Peptidase M22, glycoprotease
D6I95_RS06560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D6I95_RS06565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D6I95_RS06570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D6I95_RS06580	COG0560	Phosphoserine phosphatase
D6I95_RS06595	COG1007	ATP synthesis coupled electron transport
D6I95_RS06610	COG0713	ATP synthesis coupled electron transport
D6I95_RS06620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D6I95_RS06625	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
D6I95_RS06630	COG1034	ATP synthesis coupled electron transport
D6I95_RS06645	COG0649	NAD binding
D6I95_RS06650	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D6I95_RS06655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D6I95_RS06660	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D6I95_RS06665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D6I95_RS06680	COG0149	triose-phosphate isomerase activity
D6I95_RS06685	COG0604	alcohol dehydrogenase
D6I95_RS06705	COG1185	polyribonucleotide nucleotidyltransferase activity
D6I95_RS06710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D6I95_RS06715	COG1183	phosphatidylcholine synthase activity
D6I95_RS06720	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D6I95_RS06725	COG0440	acetolactate synthase activity
D6I95_RS06730	COG0028	Belongs to the TPP enzyme family
D6I95_RS06735	COG1289	transmembrane transporter activity
D6I95_RS06740	COG3022	response to hydroperoxide
D6I95_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS06775	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D6I95_RS06795	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D6I95_RS06800	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D6I95_RS06805	COG1674	ftsk spoiiie
D6I95_RS06810	COG0492	ferredoxin-NADP+ reductase activity
D6I95_RS06830	COG0477	Major facilitator Superfamily
D6I95_RS06850	COG2272	Belongs to the type-B carboxylesterase lipase family
D6I95_RS06855	COG1960	acyl-CoA dehydrogenase activity
D6I95_RS06880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D6I95_RS06900	COG2204	response regulator
D6I95_RS06940	COG4964	Belongs to the GSP D family
D6I95_RS06995	COG0612	Peptidase, M16
D6I95_RS07000	COG0484	heat shock protein binding
D6I95_RS07005	COG0443	Heat shock 70 kDa protein
D6I95_RS07010	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D6I95_RS07020	COG1420	regulation of RNA biosynthetic process
D6I95_RS07030	COG0497	DNA recombination
D6I95_RS07035	COG0735	belongs to the Fur family
D6I95_RS07040	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D6I95_RS07055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D6I95_RS07075	COG5001	Diguanylate cyclase
D6I95_RS07075	COG3300	MHYT domain
D6I95_RS07090	COG2814	Major facilitator Superfamily
D6I95_RS07100	COG3383	formate dehydrogenase (NAD+) activity
D6I95_RS07100	COG0243	molybdopterin cofactor binding
D6I95_RS07105	COG0437	4 iron, 4 sulfur cluster binding
D6I95_RS07110	COG2864	formate dehydrogenase
D6I95_RS07115	COG3058	Necessary for formate dehydrogenase activity
D6I95_RS07120	COG2819	hydrolase of the alpha beta superfamily
D6I95_RS07140	COG1454	alcohol dehydrogenase
D6I95_RS07175	COG1414	Transcriptional regulator
D6I95_RS07185	COG0513	Belongs to the DEAD box helicase family
D6I95_RS07195	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D6I95_RS07200	COG0583	DNA-binding transcription factor activity
D6I95_RS07205	COG4638	Rieske (2fe-2S)
D6I95_RS07210	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
D6I95_RS07225	COG0446	pyridine nucleotide-disulphide oxidoreductase
D6I95_RS07245	COG4569	acetaldehyde dehydrogenase (acetylating) activity
D6I95_RS07250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D6I95_RS07255	COG2814	Major facilitator Superfamily
D6I95_RS07270	COG0154	amidase activity
D6I95_RS07275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D6I95_RS07280	COG2814	Major facilitator Superfamily
D6I95_RS07295	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS07305	COG0842	Transport permease protein
D6I95_RS07310	COG0842	Transport permease protein
D6I95_RS07310	COG1129	ABC transporter
D6I95_RS07315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D6I95_RS07320	COG1538	Outer membrane efflux protein
D6I95_RS07325	COG3243	poly(R)-hydroxyalkanoic acid synthase
D6I95_RS07335	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D6I95_RS07340	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D6I95_RS07345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D6I95_RS07360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D6I95_RS07370	COG0633	Ferredoxin
D6I95_RS07375	COG0505	Belongs to the CarA family
D6I95_RS07380	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
D6I95_RS07390	COG0789	Transcriptional regulator
D6I95_RS07400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D6I95_RS07440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D6I95_RS07460	COG1459	type II secretion system
D6I95_RS07520	COG0517	IMP dehydrogenase activity
D6I95_RS07520	COG0516	GMP reductase activity
D6I95_RS07535	COG1027	Aspartate ammonia-lyase
D6I95_RS07540	COG1846	Transcriptional regulator
D6I95_RS07550	COG0494	nUDIX hydrolase
D6I95_RS07560	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
D6I95_RS07575	COG1414	Transcriptional regulator
D6I95_RS07595	COG0513	Belongs to the DEAD box helicase family
D6I95_RS07615	COG0429	hydrolase of the alpha beta-hydrolase fold
D6I95_RS07640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D6I95_RS07650	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
D6I95_RS07660	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
D6I95_RS07665	COG0632	four-way junction helicase activity
D6I95_RS07675	COG2255	four-way junction helicase activity
D6I95_RS07685	COG0418	dihydroorotase activity
D6I95_RS07695	COG0415	Belongs to the DNA photolyase family
D6I95_RS07760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D6I95_RS07800	COG1177	transmembrane transport
D6I95_RS07805	COG3842	ATPase activity
D6I95_RS07810	COG1840	ABC-type Fe3 transport system, periplasmic component
D6I95_RS07835	COG0494	nUDIX hydrolase
D6I95_RS07840	COG0442	prolyl-tRNA aminoacylation
D6I95_RS07845	COG0824	Thioesterase
D6I95_RS07850	COG0811	peptide transport
D6I95_RS07855	COG0848	biopolymer transport protein
D6I95_RS07865	COG0823	Involved in the tonB-independent uptake of proteins
D6I95_RS07905	COG1079	Belongs to the binding-protein-dependent transport system permease family
D6I95_RS07910	COG4603	Belongs to the binding-protein-dependent transport system permease family
D6I95_RS07915	COG3845	ABC transporter
D6I95_RS07935	COG0427	acetyl-CoA hydrolase
D6I95_RS07940	COG0583	DNA-binding transcription factor activity
D6I95_RS07950	COG2814	Major facilitator Superfamily
D6I95_RS07965	COG3634	alkyl hydroperoxide reductase activity
D6I95_RS07980	COG0697	spore germination
D6I95_RS07985	COG0175	sulfate reduction
D6I95_RS08005	COG1012	belongs to the aldehyde dehydrogenase family
D6I95_RS08010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D6I95_RS08025	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D6I95_RS08040	COG0583	DNA-binding transcription factor activity
D6I95_RS08045	COG1741	Belongs to the pirin family
D6I95_RS08050	COG3706	GGDEF domain
D6I95_RS08055	COG0154	amidase activity
D6I95_RS08060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D6I95_RS08070	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D6I95_RS08075	COG0284	orotidine-5'-phosphate decarboxylase activity
D6I95_RS08100	COG1414	Transcriptional regulator
D6I95_RS08110	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D6I95_RS08120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D6I95_RS08125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D6I95_RS08150	COG0742	ribosomal rna small subunit methyltransferase
D6I95_RS08155	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D6I95_RS08160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D6I95_RS08190	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D6I95_RS08200	COG1335	isochorismatase
D6I95_RS08205	COG2309	aminopeptidase activity
D6I95_RS08210	COG0596	Alpha beta hydrolase
D6I95_RS08215	COG2010	Cytochrome c
D6I95_RS08215	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D6I95_RS08220	COG2080	2 iron, 2 sulfur cluster binding
D6I95_RS08225	COG2010	Cytochrome c
D6I95_RS08225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D6I95_RS08240	COG0411	ABC transporter
D6I95_RS08275	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS08285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D6I95_RS08295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D6I95_RS08295	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D6I95_RS08300	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D6I95_RS08300	COG3608	succinylglutamate desuccinylase aspartoacylase
D6I95_RS08305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D6I95_RS08330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D6I95_RS08355	COG1335	isochorismatase
D6I95_RS08360	COG2309	aminopeptidase activity
D6I95_RS08365	COG0596	Alpha beta hydrolase
D6I95_RS08380	COG1120	ATPase activity
D6I95_RS08385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D6I95_RS08395	COG4206	TonB-dependent receptor
D6I95_RS08400	COG2031	fatty acid transporter
D6I95_RS08420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D6I95_RS08425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D6I95_RS08430	COG0328	RNA-DNA hybrid ribonuclease activity
D6I95_RS08435	COG2226	methyltransferase
D6I95_RS08440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D6I95_RS08445	COG1388	LysM domain
D6I95_RS08445	COG0741	lytic transglycosylase activity
D6I95_RS08455	COG2204	response regulator
D6I95_RS08460	COG4191	Histidine kinase
D6I95_RS08465	COG1301	dicarboxylic acid transport
D6I95_RS08475	COG1054	Belongs to the UPF0176 family
D6I95_RS08495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D6I95_RS08520	COG0604	alcohol dehydrogenase
D6I95_RS08530	COG1024	Enoyl-CoA hydratase
D6I95_RS08580	COG1393	Belongs to the ArsC family
D6I95_RS08585	COG0431	NADPH-dependent FMN reductase
D6I95_RS08590	COG0745	RESPONSE REGULATOR receiver
D6I95_RS08595	COG0642	Histidine kinase
D6I95_RS08615	COG2814	Major facilitator Superfamily
D6I95_RS08640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D6I95_RS08640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D6I95_RS08645	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D6I95_RS08650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D6I95_RS08655	COG1881	PFAM PEBP family protein
D6I95_RS08660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D6I95_RS08665	COG0739	heme binding
D6I95_RS08670	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
D6I95_RS08690	COG0316	Belongs to the HesB IscA family
D6I95_RS08700	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D6I95_RS08705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D6I95_RS08710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D6I95_RS08715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D6I95_RS08720	COG0312	modulator of DNA gyrase
D6I95_RS08725	COG3028	Belongs to the UPF0307 family
D6I95_RS08750	COG4566	intracellular signal transduction
D6I95_RS08755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D6I95_RS08760	COG4681	YaeQ
D6I95_RS08785	COG0762	integral membrane protein
D6I95_RS08790	COG2169	Transcriptional regulator
D6I95_RS08790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D6I95_RS08795	COG3133	Outer membrane lipoprotein
D6I95_RS08800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D6I95_RS08815	COG0439	Biotin carboxylase
D6I95_RS08820	COG0511	ligase activity, forming carbon-carbon bonds
D6I95_RS08825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D6I95_RS08830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D6I95_RS08835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D6I95_RS08840	COG3150	esterase
D6I95_RS08855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D6I95_RS08860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D6I95_RS08870	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D6I95_RS08885	COG1678	Uncharacterized ACR, COG1678
D6I95_RS08900	COG0352	thiamine-phosphate diphosphorylase activity
D6I95_RS08905	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D6I95_RS08925	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D6I95_RS08935	COG3237	CsbD-like
D6I95_RS08940	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D6I95_RS08945	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D6I95_RS08950	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D6I95_RS08955	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D6I95_RS08980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D6I95_RS08995	COG1126	abc transporter atp-binding protein
D6I95_RS09000	COG0765	amino acid transport
D6I95_RS09005	COG4597	amino acid ABC transporter
D6I95_RS09010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D6I95_RS09015	COG2884	Cell division ATP-binding protein ftsE
D6I95_RS09020	COG2177	Part of the ABC transporter FtsEX involved in
D6I95_RS09030	COG0772	Belongs to the SEDS family
D6I95_RS09035	COG0768	penicillin binding
D6I95_RS09045	COG1792	Involved in formation and maintenance of cell shape
D6I95_RS09050	COG1077	Cell shape determining protein MreB Mrl
D6I95_RS09055	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D6I95_RS09060	COG0154	amidase activity
D6I95_RS09065	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D6I95_RS09070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D6I95_RS09075	COG0583	DNA-binding transcription factor activity
D6I95_RS09080	COG2259	Doxx family
D6I95_RS09085	COG3384	dioxygenase
D6I95_RS09095	COG3245	cytochrome
D6I95_RS09105	COG1846	Transcriptional regulator
D6I95_RS09110	COG1960	acyl-CoA dehydrogenase activity
D6I95_RS09115	COG2814	Major facilitator Superfamily
D6I95_RS09125	COG1024	Enoyl-CoA hydratase
D6I95_RS09140	COG3604	Transcriptional regulator
D6I95_RS09160	COG1309	transcriptional regulator
D6I95_RS09175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D6I95_RS09200	COG1090	epimerase
D6I95_RS09205	COG0786	glutamate:sodium symporter activity
D6I95_RS09210	COG0142	geranyltranstransferase activity
D6I95_RS09220	COG0494	nUDIX hydrolase
D6I95_RS09225	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D6I95_RS09240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D6I95_RS09250	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
D6I95_RS09255	COG0237	dephospho-CoA kinase activity
D6I95_RS09265	COG2197	response regulator
D6I95_RS09275	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D6I95_RS09280	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D6I95_RS09290	COG0477	Major facilitator Superfamily
D6I95_RS09305	COG4206	TonB-dependent receptor
D6I95_RS09310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D6I95_RS09325	COG1595	DNA-templated transcription, initiation
D6I95_RS09330	COG2022	thiamine diphosphate biosynthetic process
D6I95_RS09335	COG0351	phosphomethylpyrimidine kinase
D6I95_RS09340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D6I95_RS09345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D6I95_RS09355	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D6I95_RS09365	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D6I95_RS09380	COG2226	methyltransferase
D6I95_RS09385	COG0745	RESPONSE REGULATOR receiver
D6I95_RS09400	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D6I95_RS09405	COG1984	allophanate hydrolase subunit 2
D6I95_RS09410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D6I95_RS09415	COG1238	metal cluster binding
D6I95_RS09440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D6I95_RS09445	COG4988	ABC transporter
D6I95_RS09455	COG1294	oxidase, subunit
D6I95_RS09460	COG1271	oxidase subunit
D6I95_RS09475	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D6I95_RS09490	COG1137	ATPase activity
D6I95_RS09500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D6I95_RS09510	COG1660	Displays ATPase and GTPase activities
D6I95_RS09520	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D6I95_RS09525	COG0792	nuclease activity
D6I95_RS09530	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D6I95_RS09545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D6I95_RS09555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D6I95_RS09560	COG0793	Belongs to the peptidase S41A family
D6I95_RS09565	COG4942	peptidase
D6I95_RS09570	COG0588	phosphoglycerate mutase activity
D6I95_RS09575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D6I95_RS09585	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
D6I95_RS09590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D6I95_RS09595	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS09600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D6I95_RS09605	COG1040	competence protein
D6I95_RS09610	COG2226	methyltransferase
D6I95_RS09620	COG2204	response regulator
D6I95_RS09640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D6I95_RS09655	COG3473	Maleate cis-trans isomerase
D6I95_RS09670	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D6I95_RS09700	COG1215	transferase activity, transferring glycosyl groups
D6I95_RS09710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D6I95_RS09725	COG1088	dTDP-glucose 4,6-dehydratase activity
D6I95_RS09730	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D6I95_RS09750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D6I95_RS09760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D6I95_RS09765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D6I95_RS09770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D6I95_RS09785	COG0356	it plays a direct role in the translocation of protons across the membrane
D6I95_RS09795	COG1024	Enoyl-CoA hydratase
D6I95_RS09810	COG0037	tRNA processing
D6I95_RS09815	COG0163	prenyltransferase activity
D6I95_RS09820	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D6I95_RS09825	COG2890	protein-(glutamine-N5) methyltransferase activity
D6I95_RS09870	COG3180	Ammonia monooxygenase
D6I95_RS09890	COG5002	protein histidine kinase activity
D6I95_RS09905	COG0477	Major facilitator Superfamily
D6I95_RS09910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D6I95_RS09925	COG1116	anion transmembrane transporter activity
D6I95_RS09950	COG3383	formate dehydrogenase (NAD+) activity
D6I95_RS09950	COG0243	molybdopterin cofactor binding
D6I95_RS09955	COG0243	molybdopterin cofactor binding
D6I95_RS09955	COG3383	formate dehydrogenase (NAD+) activity
D6I95_RS09960	COG0437	4 iron, 4 sulfur cluster binding
D6I95_RS09965	COG2864	formate dehydrogenase
D6I95_RS09970	COG3058	Necessary for formate dehydrogenase activity
D6I95_RS09975	COG1921	L-seryl-tRNASec selenium transferase activity
D6I95_RS09980	COG3276	selenocysteine insertion sequence binding
D6I95_RS09990	COG1476	TRANSCRIPTIONal
D6I95_RS09995	COG0235	Class ii aldolase
D6I95_RS10005	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS10035	COG0709	Synthesizes selenophosphate from selenide and ATP
D6I95_RS10040	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
D6I95_RS10045	COG0348	domain, Protein
D6I95_RS10045	COG3901	Regulator of nitric oxide reductase transcription
D6I95_RS10050	COG4263	nitrous-oxide reductase activity
D6I95_RS10065	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D6I95_RS10080	COG0166	Belongs to the GPI family
D6I95_RS10100	COG1215	transferase activity, transferring glycosyl groups
D6I95_RS10135	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D6I95_RS10170	COG0156	8-amino-7-oxononanoate synthase activity
D6I95_RS10175	COG3321	synthase
D6I95_RS10175	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS10175	COG0604	alcohol dehydrogenase
D6I95_RS10180	COG2233	PERMEase
D6I95_RS10185	COG0697	spore germination
D6I95_RS10190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D6I95_RS10195	COG0697	spore germination
D6I95_RS10205	COG0183	Belongs to the thiolase family
D6I95_RS10210	COG1024	Enoyl-CoA hydratase
D6I95_RS10210	COG1250	3-hydroxyacyl-CoA dehydrogenase
D6I95_RS10225	COG0583	DNA-binding transcription factor activity
D6I95_RS10230	COG2828	Protein conserved in bacteria
D6I95_RS10235	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS10240	COG1127	ABC transporter
D6I95_RS10245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D6I95_RS10250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D6I95_RS10265	COG1131	(ABC) transporter
D6I95_RS10270	COG0842	Transport permease protein
D6I95_RS10280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D6I95_RS10290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D6I95_RS10295	COG0131	Imidazoleglycerol-phosphate dehydratase
D6I95_RS10305	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D6I95_RS10310	COG0107	imidazoleglycerol-phosphate synthase activity
D6I95_RS10315	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D6I95_RS10320	COG0140	phosphoribosyl-ATP diphosphatase activity
D6I95_RS10325	COG0537	adenosine 5'-monophosphoramidase activity
D6I95_RS10330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D6I95_RS10345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D6I95_RS10355	COG1970	mechanosensitive ion channel activity
D6I95_RS10360	COG0723	plastoquinol--plastocyanin reductase activity
D6I95_RS10365	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D6I95_RS10370	COG2857	Cytochrome c1
D6I95_RS10375	COG0625	glutathione transferase activity
D6I95_RS10380	COG2969	positive regulation of protein catabolic process
D6I95_RS10385	COG4208	sulfate ABC transporter
D6I95_RS10390	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D6I95_RS10395	COG4150	thiosulfate binding
D6I95_RS10410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D6I95_RS10430	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D6I95_RS10435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D6I95_RS10440	COG3622	Belongs to the hyi family
D6I95_RS10445	COG2084	Dehydrogenase
D6I95_RS10450	COG0129	dihydroxy-acid dehydratase activity
D6I95_RS10455	COG1802	Transcriptional regulator
D6I95_RS10460	COG1522	sequence-specific DNA binding
D6I95_RS10465	COG3483	tryptophan 2,3-dioxygenase activity
D6I95_RS10480	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D6I95_RS10485	COG0656	L-ascorbic acid biosynthetic process
D6I95_RS10495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D6I95_RS10500	COG3706	GGDEF domain
D6I95_RS10505	COG2226	methyltransferase
D6I95_RS10515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D6I95_RS10530	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
D6I95_RS10535	COG0583	DNA-binding transcription factor activity
D6I95_RS10540	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS10555	COG2823	Periplasmic or secreted lipoprotein
D6I95_RS10565	COG3284	Transcriptional regulator
D6I95_RS10595	COG1595	DNA-templated transcription, initiation
D6I95_RS10610	COG1522	sequence-specific DNA binding
D6I95_RS10615	COG0438	transferase activity, transferring glycosyl groups
D6I95_RS10620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D6I95_RS10640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D6I95_RS10675	COG0109	protoheme IX farnesyltransferase activity
D6I95_RS10680	COG4753	response regulator
D6I95_RS10680	COG2207	Transcriptional regulator
D6I95_RS10725	COG3568	Endonuclease Exonuclease Phosphatase
D6I95_RS10730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D6I95_RS10755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D6I95_RS10765	COG1228	amidohydrolase
D6I95_RS10775	COG2986	histidine ammonia-lyase
D6I95_RS10780	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D6I95_RS10805	COG0789	Transcriptional regulator
D6I95_RS10835	COG0625	glutathione transferase activity
D6I95_RS10860	COG1448	Aminotransferase
D6I95_RS10865	COG2365	Tyrosine phosphatase family
D6I95_RS10870	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D6I95_RS10890	COG2423	ornithine cyclodeaminase activity
D6I95_RS10940	COG3069	C4-dicarboxylate transmembrane transporter activity
D6I95_RS10950	COG1802	Transcriptional regulator
D6I95_RS10970	COG2814	Major facilitator Superfamily
D6I95_RS10980	COG2814	Major facilitator Superfamily
D6I95_RS10990	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D6I95_RS10995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D6I95_RS11000	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D6I95_RS11020	COG5001	Diguanylate cyclase
D6I95_RS11020	COG5002	protein histidine kinase activity
D6I95_RS11025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D6I95_RS11030	COG1333	cytochrome c biogenesis protein
D6I95_RS11040	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D6I95_RS11050	COG4232	protein-disulfide reductase activity
D6I95_RS11070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D6I95_RS11075	COG0203	ribosomal protein L17
D6I95_RS11080	COG0202	RNA polymerase activity
D6I95_RS11085	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D6I95_RS11090	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D6I95_RS11095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D6I95_RS11100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D6I95_RS11110	COG0201	protein transport
D6I95_RS11115	COG0200	Binds to the 23S rRNA
D6I95_RS11120	COG1841	ribosomal large subunit assembly
D6I95_RS11125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D6I95_RS11130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D6I95_RS11135	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D6I95_RS11140	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D6I95_RS11145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D6I95_RS11150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D6I95_RS11155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D6I95_RS11160	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D6I95_RS11185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D6I95_RS11190	COG2274	protein secretion by the type I secretion system
D6I95_RS11200	COG1538	Outer membrane efflux protein
D6I95_RS11220	COG1960	acyl-CoA dehydrogenase activity
D6I95_RS11235	COG2067	long-chain fatty acid transport protein
D6I95_RS11250	COG0318	PFAM AMP-dependent synthetase and ligase
D6I95_RS11255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D6I95_RS11260	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D6I95_RS11265	COG1648	precorrin-2 dehydrogenase activity
D6I95_RS11265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D6I95_RS11280	COG1116	anion transmembrane transporter activity
D6I95_RS11285	COG1960	acyl-CoA dehydrogenase activity
D6I95_RS11300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D6I95_RS11305	COG0255	Belongs to the universal ribosomal protein uL29 family
D6I95_RS11310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D6I95_RS11315	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D6I95_RS11320	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D6I95_RS11325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D6I95_RS11330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D6I95_RS11335	COG0089	rRNA binding
D6I95_RS11340	COG0088	Forms part of the polypeptide exit tunnel
D6I95_RS11345	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D6I95_RS11350	COG4175	Glycine betaine
D6I95_RS11355	COG4176	ABC-type proline glycine betaine transport system permease component
D6I95_RS11360	COG0051	transcription antitermination factor activity, RNA binding
D6I95_RS11365	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D6I95_RS11370	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D6I95_RS11375	COG0049	tRNA binding
D6I95_RS11380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D6I95_RS11410	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
D6I95_RS11415	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D6I95_RS11420	COG0085	RNA polymerase activity
D6I95_RS11425	COG0222	ribosome binding
D6I95_RS11430	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D6I95_RS11435	COG0081	regulation of translation
D6I95_RS11460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D6I95_RS11480	COG1475	DNA binding
D6I95_RS11485	COG1192	Involved in chromosome partitioning
D6I95_RS11490	COG0357	Ribosomal RNA small subunit methyltransferase G
D6I95_RS11495	COG0445	tRNA wobble uridine modification
D6I95_RS11500	COG0436	Aminotransferase
D6I95_RS11505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D6I95_RS11510	COG3706	GGDEF domain
D6I95_RS11515	COG0688	phosphatidylethanolamine metabolic process
D6I95_RS11525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D6I95_RS11570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D6I95_RS11615	COG0753	catalase activity
D6I95_RS11620	COG0706	membrane insertase activity
D6I95_RS11625	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D6I95_RS11630	COG0594	ribonuclease P activity
D6I95_RS11635	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D6I95_RS11640	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D6I95_RS11645	COG0592	DNA-directed DNA polymerase activity
D6I95_RS11665	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS11670	COG1012	belongs to the aldehyde dehydrogenase family
D6I95_RS11680	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS11685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D6I95_RS11695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D6I95_RS11715	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D6I95_RS11720	COG0583	DNA-binding transcription factor activity
D6I95_RS11730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D6I95_RS11745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D6I95_RS11755	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS11765	COG0697	spore germination
D6I95_RS11770	COG0523	cobalamin synthesis protein
D6I95_RS11790	COG0625	glutathione transferase activity
D6I95_RS11830	COG1846	Transcriptional regulator
D6I95_RS11850	COG0179	Fumarylacetoacetate (FAA) hydrolase
D6I95_RS11855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D6I95_RS11860	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
D6I95_RS11870	COG4638	Rieske (2fe-2S)
D6I95_RS11915	COG0662	Cupin 2, conserved barrel domain protein
D6I95_RS11920	COG2207	Transcriptional regulator
D6I95_RS11930	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS11955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D6I95_RS11975	COG4608	Belongs to the ABC transporter superfamily
D6I95_RS11980	COG0444	Belongs to the ABC transporter superfamily
D6I95_RS11985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D6I95_RS11990	COG0601	transmembrane transport
D6I95_RS11995	COG0747	negative chemotaxis
D6I95_RS12000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D6I95_RS12005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D6I95_RS12010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D6I95_RS12050	COG4149	molybdate abc transporter
D6I95_RS12060	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D6I95_RS12070	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D6I95_RS12080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D6I95_RS12100	COG0028	Belongs to the TPP enzyme family
D6I95_RS12105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D6I95_RS12125	COG3391	amine dehydrogenase activity
D6I95_RS12145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D6I95_RS12145	COG0551	DNA topoisomerase type I activity
D6I95_RS12155	COG2922	Belongs to the Smg family
D6I95_RS12175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D6I95_RS12180	COG0183	Belongs to the thiolase family
D6I95_RS12185	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
D6I95_RS12190	COG1960	acyl-CoA dehydrogenase activity
D6I95_RS12210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D6I95_RS12220	COG0018	arginyl-trna synthetase
D6I95_RS12245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D6I95_RS12255	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D6I95_RS12260	COG4774	siderophore transport
D6I95_RS12265	COG0066	3-isopropylmalate dehydratase activity
D6I95_RS12270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D6I95_RS12275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D6I95_RS12280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D6I95_RS12285	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D6I95_RS12285	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D6I95_RS12295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D6I95_RS12300	COG1335	isochorismatase
D6I95_RS12305	COG0583	DNA-binding transcription factor activity
D6I95_RS12325	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D6I95_RS12330	COG1280	lysine exporter protein (LysE YggA)
D6I95_RS12335	COG0513	Belongs to the DEAD box helicase family
D6I95_RS12345	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D6I95_RS12360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D6I95_RS12375	COG0154	amidase activity
D6I95_RS12390	COG0583	DNA-binding transcription factor activity
D6I95_RS12420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D6I95_RS12425	COG1127	ABC transporter
D6I95_RS12440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D6I95_RS12445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D6I95_RS12455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D6I95_RS12490	COG2186	Transcriptional regulator
D6I95_RS12500	COG0583	DNA-binding transcription factor activity
D6I95_RS12525	COG1254	Belongs to the acylphosphatase family
D6I95_RS12535	COG2358	TRAP transporter, solute receptor (TAXI family
D6I95_RS12545	COG0564	pseudouridine synthase activity
D6I95_RS12550	COG0252	asparaginase activity
D6I95_RS12575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D6I95_RS12580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D6I95_RS12585	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS12605	COG0559	Belongs to the binding-protein-dependent transport system permease family
D6I95_RS12630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D6I95_RS12645	COG0758	DNA mediated transformation
D6I95_RS12650	COG0242	peptide deformylase activity
D6I95_RS12655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D6I95_RS12660	COG0697	spore germination
D6I95_RS12675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D6I95_RS12690	COG4336	lyase activity
D6I95_RS12695	COG0583	DNA-binding transcription factor activity
D6I95_RS12700	COG0859	PFAM glycosyl transferase family 9
D6I95_RS12710	COG1278	Cold shock
D6I95_RS12715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D6I95_RS12720	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D6I95_RS12725	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D6I95_RS12725	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D6I95_RS12735	COG1686	Belongs to the peptidase S11 family
D6I95_RS12745	COG2921	Belongs to the UPF0250 family
D6I95_RS12750	COG0321	lipoyl(octanoyl) transferase activity
D6I95_RS12755	COG1024	Enoyl-CoA hydratase
D6I95_RS12760	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D6I95_RS12770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D6I95_RS12815	COG0826	peptidase U32
D6I95_RS12825	COG3154	lipid carrier protein
D6I95_RS12850	COG0134	indole-3-glycerol-phosphate synthase activity
D6I95_RS12855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D6I95_RS12860	COG0512	Glutamine amidotransferase of anthranilate synthase
D6I95_RS12870	COG0546	phosphoglycolate phosphatase activity
D6I95_RS12880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D6I95_RS12885	COG2967	ApaG domain
D6I95_RS12890	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D6I95_RS12895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D6I95_RS12900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D6I95_RS12910	COG0840	transmembrane signaling receptor activity
D6I95_RS12920	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS12925	COG1535	isochorismatase
D6I95_RS12925	COG3433	isochorismatase activity
D6I95_RS12930	COG1169	isochorismate synthase
D6I95_RS12945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D6I95_RS12950	COG1535	isochorismatase
D6I95_RS12950	COG3433	isochorismatase activity
D6I95_RS12955	COG1021	2,3-dihydroxybenzoate-AMP ligase
D6I95_RS12970	COG0411	ABC transporter
D6I95_RS12985	COG0683	leucine binding
D6I95_RS13000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D6I95_RS13035	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
D6I95_RS13040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D6I95_RS13045	COG2819	hydrolase of the alpha beta superfamily
D6I95_RS13050	COG0513	Belongs to the DEAD box helicase family
D6I95_RS13055	COG2814	Major facilitator Superfamily
D6I95_RS13075	COG1253	flavin adenine dinucleotide binding
D6I95_RS13105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D6I95_RS13135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D6I95_RS13155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D6I95_RS13160	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D6I95_RS13170	COG0583	DNA-binding transcription factor activity
D6I95_RS13175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D6I95_RS13180	COG1126	abc transporter atp-binding protein
D6I95_RS13185	COG0765	amino acid transport
D6I95_RS13190	COG0765	amino acid transport
D6I95_RS13195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D6I95_RS13200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D6I95_RS13215	COG3391	amine dehydrogenase activity
D6I95_RS13225	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D6I95_RS13250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D6I95_RS13255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D6I95_RS13260	COG0210	DNA helicase
D6I95_RS13285	COG0067	glutamate synthase
D6I95_RS13285	COG0069	glutamate synthase activity
D6I95_RS13285	COG0070	glutamate synthase
D6I95_RS13295	COG1024	Enoyl-CoA hydratase
D6I95_RS13305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D6I95_RS13310	COG1250	3-hydroxyacyl-CoA dehydrogenase
D6I95_RS13335	COG2918	glutathione biosynthetic process
D6I95_RS13345	COG2197	response regulator
D6I95_RS13350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D6I95_RS13360	COG2223	nitrite transmembrane transporter activity
D6I95_RS13365	COG2860	membrane
D6I95_RS13370	COG1346	cytolysis
D6I95_RS13385	COG0251	oxidation-reduction process
D6I95_RS13410	COG1280	lysine exporter protein (LysE YggA)
D6I95_RS13435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D6I95_RS13450	COG2096	Adenosyltransferase
D6I95_RS13465	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D6I95_RS13470	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D6I95_RS13480	COG0523	cobalamin synthesis protein
D6I95_RS13485	COG0735	belongs to the Fur family
D6I95_RS13495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D6I95_RS13500	COG0803	Belongs to the bacterial solute-binding protein 9 family
D6I95_RS13505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D6I95_RS13515	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D6I95_RS13520	COG1560	Kdo2-lipid A biosynthetic process
D6I95_RS13530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D6I95_RS13535	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D6I95_RS13540	COG1950	PFAM Membrane protein of
D6I95_RS13575	COG0275	rRNA processing
D6I95_RS13580	COG0730	response to heat
D6I95_RS13585	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D6I95_RS13590	COG0129	dihydroxy-acid dehydratase activity
D6I95_RS13605	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D6I95_RS13625	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS13635	COG0628	permease
D6I95_RS13665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D6I95_RS13725	COG0252	asparaginase activity
D6I95_RS13730	COG1027	Aspartate ammonia-lyase
D6I95_RS13735	COG1115	amino acid carrier protein
D6I95_RS13750	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS13755	COG1846	Transcriptional regulator
D6I95_RS13765	COG4774	siderophore transport
D6I95_RS13770	COG4607	ABC-type enterochelin transport system periplasmic component
D6I95_RS13775	COG4604	ABC transporter, ATP-binding protein
D6I95_RS13780	COG4605	iron ion homeostasis
D6I95_RS13785	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D6I95_RS13795	COG1132	(ABC) transporter
D6I95_RS13795	COG2375	cellular response to nickel ion
D6I95_RS13800	COG0277	FAD linked oxidase domain protein
D6I95_RS13805	COG1304	FMN binding
D6I95_RS13810	COG2186	Transcriptional regulator
D6I95_RS13830	COG2188	Transcriptional regulator
D6I95_RS13835	COG1522	sequence-specific DNA binding
D6I95_RS13845	COG1113	amino acid transport
D6I95_RS13850	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D6I95_RS13855	COG1349	DNA-binding transcription factor activity
D6I95_RS13875	COG0395	ABC-type sugar transport system, permease component
D6I95_RS13890	COG0861	Integral membrane protein TerC family
D6I95_RS13895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D6I95_RS13900	COG2801	Transposase and inactivated derivatives
D6I95_RS13910	COG1671	Belongs to the UPF0178 family
D6I95_RS13920	COG1418	mRNA catabolic process
D6I95_RS13930	COG0477	Major facilitator Superfamily
D6I95_RS13945	COG0154	amidase activity
D6I95_RS13955	COG0583	DNA-binding transcription factor activity
D6I95_RS13980	COG0326	Molecular chaperone. Has ATPase activity
D6I95_RS13985	COG4774	siderophore transport
D6I95_RS13990	COG3128	pkhd-type hydroxylase
D6I95_RS14015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D6I95_RS14020	COG1652	LysM domain
D6I95_RS14035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D6I95_RS14085	COG0477	Major facilitator Superfamily
D6I95_RS14090	COG0235	Class ii aldolase
D6I95_RS14100	COG3391	amine dehydrogenase activity
D6I95_RS14105	COG0590	tRNA wobble adenosine to inosine editing
D6I95_RS14110	COG3257	ureidoglycine aminohydrolase activity
D6I95_RS14115	COG0583	DNA-binding transcription factor activity
D6I95_RS14120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D6I95_RS14125	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D6I95_RS14125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D6I95_RS14135	COG0489	protein tyrosine kinase activity
D6I95_RS14160	COG2081	HI0933 family
D6I95_RS14165	COG0509	glycine decarboxylation via glycine cleavage system
D6I95_RS14175	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D6I95_RS14180	COG1765	OsmC-like protein
D6I95_RS14210	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
D6I95_RS14215	COG0469	pyruvate kinase activity
D6I95_RS14220	COG3193	protein, possibly involved in utilization of glycolate and propanediol
D6I95_RS14230	COG2084	Dehydrogenase
D6I95_RS14235	COG3622	Belongs to the hyi family
D6I95_RS14240	COG3960	tartronate-semialdehyde synthase activity
D6I95_RS14245	COG0583	DNA-binding transcription factor activity
D6I95_RS14255	COG2233	PERMEase
D6I95_RS14260	COG1942	4-Oxalocrotonate Tautomerase
D6I95_RS14270	COG3195	allantoin biosynthetic process
D6I95_RS14270	COG3648	Uricase
D6I95_RS14280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D6I95_RS14285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D6I95_RS14300	COG0438	transferase activity, transferring glycosyl groups
D6I95_RS14310	COG0438	transferase activity, transferring glycosyl groups
D6I95_RS14320	COG0277	FAD linked oxidase domain protein
D6I95_RS14345	COG0179	Fumarylacetoacetate (FAA) hydrolase
D6I95_RS14350	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
D6I95_RS14360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D6I95_RS14370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D6I95_RS14380	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
D6I95_RS14395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D6I95_RS14400	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D6I95_RS14405	COG0193	aminoacyl-tRNA hydrolase activity
D6I95_RS14415	COG0012	GTP binding
D6I95_RS14430	COG4804	nuclease activity
D6I95_RS14435	COG0732	type I restriction modification DNA specificity domain
D6I95_RS14440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D6I95_RS14485	COG0488	(ABC) transporter
D6I95_RS14495	COG0288	reversible hydration of carbon dioxide
D6I95_RS14500	COG0583	DNA-binding transcription factor activity
D6I95_RS14540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D6I95_RS14545	COG3088	subunit of a heme lyase
D6I95_RS14550	COG4235	cytochrome complex assembly
D6I95_RS14555	COG0785	Cytochrome C biogenesis protein
D6I95_RS14565	COG2169	Transcriptional regulator
D6I95_RS14565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D6I95_RS14585	COG0559	Belongs to the binding-protein-dependent transport system permease family
D6I95_RS14595	COG0411	ABC transporter
D6I95_RS14605	COG1858	cytochrome C peroxidase
D6I95_RS14610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D6I95_RS14615	COG1959	2 iron, 2 sulfur cluster binding
D6I95_RS14620	COG2346	COG2346, Truncated hemoglobins
D6I95_RS14660	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D6I95_RS14665	COG3383	formate dehydrogenase (NAD+) activity
D6I95_RS14680	COG1910	domain protein
D6I95_RS14685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D6I95_RS14705	COG0303	'Molybdopterin
D6I95_RS14710	COG0521	Mo-molybdopterin cofactor biosynthetic process
D6I95_RS14715	COG0314	molybdopterin synthase activity
D6I95_RS14725	COG0315	cyclic pyranopterin monophosphate synthase activity
D6I95_RS14755	COG0678	peroxiredoxin activity
D6I95_RS14770	COG0697	spore germination
D6I95_RS14775	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D6I95_RS14795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D6I95_RS14820	COG0604	alcohol dehydrogenase
D6I95_RS14835	COG1309	transcriptional regulator
D6I95_RS14845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D6I95_RS14895	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D6I95_RS14900	COG4535	Mg2 and Co2 transporter CorC
D6I95_RS14905	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D6I95_RS14910	COG1702	phosphate starvation-inducible protein PhoH
D6I95_RS14915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D6I95_RS14930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D6I95_RS14935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D6I95_RS14940	COG1862	Preprotein translocase
D6I95_RS14945	COG0343	queuine tRNA-ribosyltransferase activity
D6I95_RS14950	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D6I95_RS14955	COG2027	D-alanyl-D-alanine carboxypeptidase
D6I95_RS14960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D6I95_RS14970	COG4575	ribosome binding
D6I95_RS14985	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D6I95_RS14995	COG0436	Aminotransferase
D6I95_RS15005	COG0281	malic enzyme
D6I95_RS15005	COG0280	phosphate acetyltransferase
D6I95_RS15015	COG2732	(Barnase) inhibitor
D6I95_RS15020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D6I95_RS15025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D6I95_RS15030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D6I95_RS15035	COG0126	phosphoglycerate kinase activity
D6I95_RS15060	COG0521	Mo-molybdopterin cofactor biosynthetic process
D6I95_RS15070	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D6I95_RS15075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D6I95_RS15080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D6I95_RS15085	COG0009	L-threonylcarbamoyladenylate synthase
D6I95_RS15090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D6I95_RS15100	COG1012	belongs to the aldehyde dehydrogenase family
D6I95_RS15100	COG2030	dehydratase
D6I95_RS15105	COG1960	acyl-CoA dehydrogenase activity
D6I95_RS15115	COG0405	Gamma-glutamyltransferase
D6I95_RS15125	COG0579	oxidoreductase
D6I95_RS15130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D6I95_RS15135	COG0259	pyridoxamine-phosphate oxidase activity
D6I95_RS15145	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D6I95_RS15160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D6I95_RS15175	COG0488	(ABC) transporter
D6I95_RS15195	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
D6I95_RS15200	COG2894	cell division
D6I95_RS15210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D6I95_RS15220	COG1294	oxidase, subunit
D6I95_RS15225	COG0038	chloride channel
D6I95_RS15235	COG0514	ATP-dependent DNA helicase (RecQ)
D6I95_RS15240	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D6I95_RS15245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D6I95_RS15250	COG0633	Ferredoxin
D6I95_RS15255	COG0488	(ABC) transporter
D6I95_RS15265	COG2001	Belongs to the MraZ family
D6I95_RS15270	COG0275	rRNA processing
D6I95_RS15275	COG3116	cell division
D6I95_RS15285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D6I95_RS15290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D6I95_RS15295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D6I95_RS15305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D6I95_RS15310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D6I95_RS15315	COG1181	Belongs to the D-alanine--D-alanine ligase family
D6I95_RS15320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D6I95_RS15335	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
D6I95_RS15345	COG0741	lytic transglycosylase activity
D6I95_RS15345	COG0739	heme binding
D6I95_RS15345	COG1196	nuclear chromosome segregation
D6I95_RS15350	COG0653	protein targeting
D6I95_RS15365	COG2239	Acts as a magnesium transporter
D6I95_RS15375	COG1473	amidohydrolase
D6I95_RS15380	COG0318	PFAM AMP-dependent synthetase and ligase
D6I95_RS15390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D6I95_RS15390	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
D6I95_RS15405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D6I95_RS15410	COG2011	ABC-type metal ion transport system permease component
D6I95_RS15420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D6I95_RS15425	COG0765	amino acid transport
D6I95_RS15430	COG1126	abc transporter atp-binding protein
D6I95_RS15440	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D6I95_RS15455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D6I95_RS15460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D6I95_RS15465	COG0700	Nucleoside recognition
D6I95_RS15480	COG0204	Acyl-transferase
D6I95_RS15485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D6I95_RS15490	COG0751	glycine-tRNA ligase activity
D6I95_RS15495	COG0752	glycyl-tRNA synthetase alpha subunit
D6I95_RS15510	COG1309	transcriptional regulator
D6I95_RS15530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D6I95_RS15535	COG0617	tRNA 3'-terminal CCA addition
D6I95_RS15545	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D6I95_RS15550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D6I95_RS15555	COG1953	Uracil, thiamine, allantoin
D6I95_RS15560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D6I95_RS15565	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D6I95_RS15570	COG0586	Pfam SNARE associated Golgi protein
D6I95_RS15575	COG0860	N-Acetylmuramoyl-L-alanine amidase
D6I95_RS15580	COG0802	atpase or kinase
D6I95_RS15590	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS15595	COG0281	malic enzyme
D6I95_RS15595	COG0280	phosphate acetyltransferase
D6I95_RS15600	COG0583	DNA-binding transcription factor activity
D6I95_RS15605	COG1012	belongs to the aldehyde dehydrogenase family
D6I95_RS15610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D6I95_RS15630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D6I95_RS15650	COG1733	regulation of RNA biosynthetic process
D6I95_RS15655	COG2910	NAD(P)H-binding
D6I95_RS15665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D6I95_RS15670	COG4974	Belongs to the 'phage' integrase family
D6I95_RS15675	COG0725	ABC transporter, periplasmic molybdate-binding protein
D6I95_RS15680	COG4149	molybdate abc transporter
D6I95_RS15685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D6I95_RS15700	COG1074	ATP-dependent DNA helicase activity
D6I95_RS15735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D6I95_RS15755	COG3391	amine dehydrogenase activity
D6I95_RS15760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D6I95_RS15765	COG0505	Belongs to the CarA family
D6I95_RS15770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D6I95_RS15795	COG2233	PERMEase
D6I95_RS15800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D6I95_RS15805	COG1534	Rna-binding protein
D6I95_RS15810	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
D6I95_RS15815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D6I95_RS15820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D6I95_RS15825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D6I95_RS15835	COG0248	Ppx GppA phosphatase
D6I95_RS15840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D6I95_RS15860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D6I95_RS15870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D6I95_RS15925	COG1368	sulfuric ester hydrolase activity
D6I95_RS15955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D6I95_RS15960	COG3327	negative regulation of DNA-templated transcription, initiation
D6I95_RS15965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D6I95_RS15980	COG0009	L-threonylcarbamoyladenylate synthase
D6I95_RS15985	COG1994	Peptidase M50
D6I95_RS15990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D6I95_RS15995	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
D6I95_RS16010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D6I95_RS16020	COG0156	8-amino-7-oxononanoate synthase activity
D6I95_RS16025	COG2124	cytochrome p450
D6I95_RS16030	COG3135	benzoate transporter
D6I95_RS16040	COG2850	peptidyl-arginine hydroxylation
D6I95_RS16045	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D6I95_RS16050	COG3391	amine dehydrogenase activity
D6I95_RS16095	COG0577	efflux transmembrane transporter activity
D6I95_RS16095	COG1136	(ABC) transporter
D6I95_RS16100	COG1538	Outer membrane efflux protein
D6I95_RS16105	COG0363	glucosamine-6-phosphate deaminase activity
D6I95_RS16110	COG1132	(ABC) transporter
D6I95_RS16120	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D6I95_RS16140	COG0668	transmembrane transport
D6I95_RS16160	COG0483	inositol monophosphate 1-phosphatase activity
D6I95_RS16165	COG1253	flavin adenine dinucleotide binding
D6I95_RS16170	COG1968	undecaprenyl-diphosphatase activity
D6I95_RS16190	COG0215	cysteine-tRNA ligase activity
D6I95_RS16200	COG0825	malonyl-CoA metabolic process
D6I95_RS16225	COG0330	HflC and HflK could
D6I95_RS16240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D6I95_RS16260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D6I95_RS16265	COG4208	sulfate ABC transporter
D6I95_RS16270	COG3842	ATPase activity
D6I95_RS16280	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
D6I95_RS16305	COG1304	FMN binding
D6I95_RS16310	COG0435	Glutathione S-transferase
D6I95_RS16315	COG0655	NAD(P)H dehydrogenase (quinone) activity
D6I95_RS16330	COG2094	Belongs to the DNA glycosylase MPG family
D6I95_RS16335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D6I95_RS16340	COG2363	Small membrane protein
D6I95_RS16345	COG0598	Magnesium transport protein CorA
D6I95_RS16350	COG1960	acyl-CoA dehydrogenase activity
D6I95_RS16360	COG0747	negative chemotaxis
D6I95_RS16370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D6I95_RS16375	COG4172	Belongs to the ABC transporter superfamily
D6I95_RS16385	COG3284	Transcriptional regulator
D6I95_RS16390	COG1012	belongs to the aldehyde dehydrogenase family
D6I95_RS16395	COG1454	alcohol dehydrogenase
D6I95_RS16420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D6I95_RS16430	COG0183	Belongs to the thiolase family
D6I95_RS16435	COG0318	PFAM AMP-dependent synthetase and ligase
D6I95_RS16445	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS16450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D6I95_RS16490	COG3829	transcription factor binding
D6I95_RS16495	COG0477	Major facilitator Superfamily
D6I95_RS16505	COG0039	L-malate dehydrogenase activity
D6I95_RS16510	COG2188	Transcriptional regulator
D6I95_RS16515	COG2009	succinate dehydrogenase
D6I95_RS16525	COG1053	succinate dehydrogenase
D6I95_RS16530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D6I95_RS16535	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D6I95_RS16540	COG0372	Belongs to the citrate synthase family
D6I95_RS16545	COG2186	Transcriptional regulator
D6I95_RS16550	COG1620	l-lactate permease
D6I95_RS16555	COG0280	phosphate acetyltransferase
D6I95_RS16555	COG0281	malic enzyme
D6I95_RS16560	COG0567	Dehydrogenase, E1 component
D6I95_RS16565	COG0508	dehydrogenase complex catalyzes the overall conversion of
D6I95_RS16570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D6I95_RS16575	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D6I95_RS16590	COG2183	response to ionizing radiation
D6I95_RS16595	COG1199	ATP-dependent helicase activity
D6I95_RS16600	COG0659	secondary active sulfate transmembrane transporter activity
D6I95_RS16610	COG0564	pseudouridine synthase activity
D6I95_RS16620	COG3243	poly(R)-hydroxyalkanoic acid synthase
D6I95_RS16625	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS16630	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
D6I95_RS16655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D6I95_RS16660	COG1187	pseudouridine synthase activity
D6I95_RS16665	COG0779	Required for maturation of 30S ribosomal subunits
D6I95_RS16670	COG0195	Participates in both transcription termination and antitermination
D6I95_RS16670	COG2251	uridine kinase activity
D6I95_RS16675	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D6I95_RS16680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D6I95_RS16685	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D6I95_RS16690	COG1217	gtp-binding protein TYPA
D6I95_RS16705	COG4160	amino acid transport
D6I95_RS16710	COG4215	(ABC) transporter
D6I95_RS16720	COG1611	Belongs to the LOG family
D6I95_RS16730	COG1283	sodium-dependent phosphate transmembrane transporter activity
D6I95_RS16735	COG0501	Belongs to the peptidase M48B family
D6I95_RS16750	COG1722	exodeoxyribonuclease VII activity
D6I95_RS16755	COG0142	geranyltranstransferase activity
D6I95_RS16760	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D6I95_RS16765	COG1469	GTP cyclohydrolase I activity
D6I95_RS16770	COG0360	Binds together with S18 to 16S ribosomal RNA
D6I95_RS16775	COG2965	DNA replication, synthesis of RNA primer
D6I95_RS16780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D6I95_RS16790	COG0305	Participates in initiation and elongation during chromosome replication
D6I95_RS16800	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D6I95_RS16805	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D6I95_RS16810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D6I95_RS16815	COG3737	Protein of unknown function (DUF498/DUF598)
D6I95_RS16820	COG0436	Aminotransferase
D6I95_RS16840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D6I95_RS16845	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
D6I95_RS16850	COG1562	ergosterol biosynthetic process
D6I95_RS16855	COG1562	ergosterol biosynthetic process
D6I95_RS16860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D6I95_RS16865	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS16890	COG3842	ATPase activity
D6I95_RS16895	COG1176	ABC-type spermidine putrescine transport system, permease component I
D6I95_RS16900	COG1177	transmembrane transport
D6I95_RS16910	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D6I95_RS16915	COG0704	Plays a role in the regulation of phosphate uptake
D6I95_RS16920	COG4251	negative regulation of phosphorylation
D6I95_RS16920	COG2203	Gaf domain
D6I95_RS16920	COG3706	GGDEF domain
D6I95_RS16920	COG5001	Diguanylate cyclase
D6I95_RS16925	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
D6I95_RS16930	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D6I95_RS16930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D6I95_RS16935	COG1643	Atp-dependent helicase
D6I95_RS16945	COG0438	transferase activity, transferring glycosyl groups
D6I95_RS16950	COG0726	polysaccharide deacetylase
D6I95_RS16965	COG0438	transferase activity, transferring glycosyl groups
D6I95_RS16990	COG1132	(ABC) transporter
D6I95_RS17005	COG1530	ribonuclease E activity
D6I95_RS17045	COG2186	Transcriptional regulator
D6I95_RS17050	COG0277	FAD linked oxidase domain protein
D6I95_RS17055	COG0277	FAD linked oxidase domain protein
D6I95_RS17060	COG0247	lactate metabolic process
D6I95_RS17090	COG2159	amidohydrolase
D6I95_RS17105	COG0583	DNA-binding transcription factor activity
D6I95_RS17110	COG0477	Major facilitator Superfamily
D6I95_RS17165	COG0628	permease
D6I95_RS17170	COG1283	sodium-dependent phosphate transmembrane transporter activity
D6I95_RS17180	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D6I95_RS17190	COG0697	spore germination
D6I95_RS17200	COG0583	DNA-binding transcription factor activity
D6I95_RS17210	COG3094	Invasion gene expression up-regulator, SirB
D6I95_RS17220	COG0640	Transcriptional regulator
D6I95_RS17235	COG0789	Transcriptional regulator
D6I95_RS17245	COG0659	secondary active sulfate transmembrane transporter activity
D6I95_RS17250	COG2314	TM2 domain
D6I95_RS17255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D6I95_RS17260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D6I95_RS17265	COG0791	NLP P60 protein
D6I95_RS17285	COG1360	Flagellar Motor Protein
D6I95_RS17295	COG0835	chemotaxis
D6I95_RS17300	COG0840	transmembrane signaling receptor activity
D6I95_RS17305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D6I95_RS17315	COG0745	RESPONSE REGULATOR receiver
D6I95_RS17320	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
D6I95_RS17330	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D6I95_RS17355	COG1815	bacterial-type flagellum-dependent cell motility
D6I95_RS17360	COG1558	bacterial-type flagellum-dependent cell motility
D6I95_RS17365	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D6I95_RS17370	COG1749	Flagellar hook protein flgE
D6I95_RS17405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D6I95_RS17440	COG1987	bacterial-type flagellum assembly
D6I95_RS17455	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D6I95_RS17480	COG1157	protein secretion by the type III secretion system
D6I95_RS17495	COG1766	The M ring may be actively involved in energy transduction
D6I95_RS17500	COG1677	Flagellar hook-basal body complex protein FliE
D6I95_RS17505	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D6I95_RS17530	COG1334	flagellar protein FlaG
D6I95_RS17535	COG1191	sigma factor activity
D6I95_RS17560	COG2733	membrane
D6I95_RS17565	COG0840	transmembrane signaling receptor activity
D6I95_RS17570	COG0840	transmembrane signaling receptor activity
D6I95_RS17585	COG3181	Tripartite tricarboxylate transporter family receptor
D6I95_RS17595	COG2610	gluconate transmembrane transporter activity
D6I95_RS17610	COG4974	Belongs to the 'phage' integrase family
D6I95_RS17655	COG4128	Pfam Zonular occludens toxin
D6I95_RS17665	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D6I95_RS17685	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D6I95_RS17690	COG3657	addiction module killer protein
D6I95_RS17695	COG1028	Short-chain dehydrogenase reductase Sdr
D6I95_RS17730	COG2824	Alkylphosphonate utilization operon protein PhnA
D6I95_RS17745	COG4771	TonB-dependent receptor
D6I95_RS17750	COG1858	cytochrome C peroxidase
D6I95_RS17770	COG0668	transmembrane transport
D6I95_RS17775	COG1113	amino acid transport