locus-tag	class	description
J5J84_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5J84_RS00010	COG0592	DNA-directed DNA polymerase activity
J5J84_RS00020	COG1187	pseudouridine synthase activity
J5J84_RS00035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_RS00060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_RS00065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5J84_RS00080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_RS00100	COG2070	2-Nitropropane dioxygenase
J5J84_RS00110	COG1960	acyl-CoA dehydrogenase activity
J5J84_RS00120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_RS00130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_RS00135	COG1802	Transcriptional regulator
J5J84_RS00140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_RS00160	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5J84_RS00165	COG0583	DNA-binding transcription factor activity
J5J84_RS00175	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_RS00185	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5J84_RS00200	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_RS00210	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5J84_RS00210	COG0596	Alpha beta hydrolase
J5J84_RS00215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_RS00230	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS00240	COG0697	spore germination
J5J84_RS00245	COG0583	DNA-binding transcription factor activity
J5J84_RS00255	COG3842	ATPase activity
J5J84_RS00265	COG0436	Aminotransferase
J5J84_RS00275	COG0523	cobalamin synthesis protein
J5J84_RS00330	COG1846	Transcriptional regulator
J5J84_RS00350	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5J84_RS00355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5J84_RS00360	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
J5J84_RS00370	COG4638	Rieske (2fe-2S)
J5J84_RS00425	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS00445	COG2207	Transcriptional regulator
J5J84_RS00475	COG1595	DNA-templated transcription, initiation
J5J84_RS00480	COG4608	Belongs to the ABC transporter superfamily
J5J84_RS00485	COG0444	Belongs to the ABC transporter superfamily
J5J84_RS00490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5J84_RS00495	COG0601	transmembrane transport
J5J84_RS00505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5J84_RS00510	COG1595	DNA-templated transcription, initiation
J5J84_RS00515	COG3712	iron ion homeostasis
J5J84_RS00520	COG4774	siderophore transport
J5J84_RS00525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J5J84_RS00530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5J84_RS00550	COG1464	Belongs to the NlpA lipoprotein family
J5J84_RS00555	COG1464	Belongs to the NlpA lipoprotein family
J5J84_RS00560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J5J84_RS00565	COG2011	ABC-type metal ion transport system permease component
J5J84_RS00590	COG1464	Belongs to the NlpA lipoprotein family
J5J84_RS00600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J5J84_RS00620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5J84_RS00625	COG0431	NADPH-dependent FMN reductase
J5J84_RS00660	COG4149	molybdate abc transporter
J5J84_RS00670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J5J84_RS00675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J5J84_RS00685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_RS00705	COG0028	Belongs to the TPP enzyme family
J5J84_RS00710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_RS00745	COG2922	Belongs to the Smg family
J5J84_RS00760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J5J84_RS00765	COG0183	Belongs to the thiolase family
J5J84_RS00770	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
J5J84_RS00775	COG1960	acyl-CoA dehydrogenase activity
J5J84_RS00795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J5J84_RS00805	COG0018	arginyl-trna synthetase
J5J84_RS00825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5J84_RS00840	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J5J84_RS00845	COG4774	siderophore transport
J5J84_RS00850	COG0066	3-isopropylmalate dehydratase activity
J5J84_RS00855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5J84_RS00860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5J84_RS00865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_RS00870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5J84_RS00870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_RS00880	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_RS00885	COG1335	isochorismatase
J5J84_RS00890	COG0583	DNA-binding transcription factor activity
J5J84_RS00910	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J5J84_RS00915	COG1280	lysine exporter protein (LysE YggA)
J5J84_RS00920	COG0513	Belongs to the DEAD box helicase family
J5J84_RS00930	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J5J84_RS00945	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5J84_RS00960	COG0154	amidase activity
J5J84_RS00975	COG0583	DNA-binding transcription factor activity
J5J84_RS01005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J5J84_RS01010	COG1127	ABC transporter
J5J84_RS01015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5J84_RS01015	COG3218	ABC-type transport auxiliary lipoprotein component
J5J84_RS01030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5J84_RS01035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_RS01045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_RS01080	COG0583	DNA-binding transcription factor activity
J5J84_RS01100	COG3093	addiction module antidote protein HigA
J5J84_RS01125	COG2358	TRAP transporter, solute receptor (TAXI family
J5J84_RS01135	COG0564	pseudouridine synthase activity
J5J84_RS01140	COG0252	asparaginase activity
J5J84_RS01165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5J84_RS01170	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5J84_RS01175	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS01195	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5J84_RS01220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_RS01235	COG0758	DNA mediated transformation
J5J84_RS01240	COG0242	peptide deformylase activity
J5J84_RS01245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5J84_RS01250	COG0697	spore germination
J5J84_RS01265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_RS01280	COG4336	lyase activity
J5J84_RS01285	COG0583	DNA-binding transcription factor activity
J5J84_RS01290	COG0859	PFAM glycosyl transferase family 9
J5J84_RS01300	COG1278	Cold shock
J5J84_RS01305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J5J84_RS01310	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J5J84_RS01315	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J5J84_RS01315	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J5J84_RS01325	COG1686	Belongs to the peptidase S11 family
J5J84_RS01335	COG2921	Belongs to the UPF0250 family
J5J84_RS01340	COG0321	lipoyl(octanoyl) transferase activity
J5J84_RS01345	COG1024	Enoyl-CoA hydratase
J5J84_RS01350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5J84_RS01360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J5J84_RS01405	COG0826	peptidase U32
J5J84_RS01415	COG3154	lipid carrier protein
J5J84_RS01440	COG0134	indole-3-glycerol-phosphate synthase activity
J5J84_RS01445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5J84_RS01450	COG0512	Glutamine amidotransferase of anthranilate synthase
J5J84_RS01460	COG0546	phosphoglycolate phosphatase activity
J5J84_RS01470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J5J84_RS01475	COG2967	ApaG domain
J5J84_RS01480	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J5J84_RS01485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_RS01490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J5J84_RS01500	COG0840	transmembrane signaling receptor activity
J5J84_RS01510	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS01515	COG1535	isochorismatase
J5J84_RS01515	COG3433	isochorismatase activity
J5J84_RS01520	COG1169	isochorismate synthase
J5J84_RS01535	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J5J84_RS01535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J5J84_RS01540	COG3433	isochorismatase activity
J5J84_RS01540	COG1535	isochorismatase
J5J84_RS01545	COG1021	2,3-dihydroxybenzoate-AMP ligase
J5J84_RS01575	COG0683	leucine binding
J5J84_RS01590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_RS01625	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J5J84_RS01630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5J84_RS01635	COG2819	hydrolase of the alpha beta superfamily
J5J84_RS01640	COG0513	Belongs to the DEAD box helicase family
J5J84_RS01645	COG2814	Major facilitator Superfamily
J5J84_RS01655	COG0583	DNA-binding transcription factor activity
J5J84_RS01665	COG1253	flavin adenine dinucleotide binding
J5J84_RS01705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J5J84_RS01715	COG2311	Membrane
J5J84_RS01750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5J84_RS01770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_RS01775	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J5J84_RS01785	COG0583	DNA-binding transcription factor activity
J5J84_RS01790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_RS01800	COG0765	amino acid transport
J5J84_RS01805	COG0765	amino acid transport
J5J84_RS01810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5J84_RS01825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5J84_RS01840	COG3391	amine dehydrogenase activity
J5J84_RS01850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J5J84_RS01875	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J5J84_RS01880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J5J84_RS01885	COG0210	DNA helicase
J5J84_RS01900	COG0067	glutamate synthase
J5J84_RS01900	COG0069	glutamate synthase activity
J5J84_RS01900	COG0070	glutamate synthase
J5J84_RS01905	COG1024	Enoyl-CoA hydratase
J5J84_RS01915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_RS01920	COG1250	3-hydroxyacyl-CoA dehydrogenase
J5J84_RS01950	COG2918	glutathione biosynthetic process
J5J84_RS01965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5J84_RS01975	COG2223	nitrite transmembrane transporter activity
J5J84_RS01980	COG2860	membrane
J5J84_RS01985	COG1346	cytolysis
J5J84_RS02000	COG0251	oxidation-reduction process
J5J84_RS02015	COG5295	Hep Hag repeat protein
J5J84_RS02035	COG1280	lysine exporter protein (LysE YggA)
J5J84_RS02045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5J84_RS02060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5J84_RS02075	COG2096	Adenosyltransferase
J5J84_RS02090	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J5J84_RS02095	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J5J84_RS02105	COG0523	cobalamin synthesis protein
J5J84_RS02110	COG0735	belongs to the Fur family
J5J84_RS02125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5J84_RS02130	COG0803	Belongs to the bacterial solute-binding protein 9 family
J5J84_RS02135	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J5J84_RS02145	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5J84_RS02150	COG1560	Kdo2-lipid A biosynthetic process
J5J84_RS02160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5J84_RS02165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J5J84_RS02170	COG1950	PFAM Membrane protein of
J5J84_RS02205	COG0275	rRNA processing
J5J84_RS02210	COG0730	response to heat
J5J84_RS02215	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J5J84_RS02220	COG0129	dihydroxy-acid dehydratase activity
J5J84_RS02225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J5J84_RS02245	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS02255	COG0628	permease
J5J84_RS02270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_RS02285	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS02310	COG1021	2,3-dihydroxybenzoate-AMP ligase
J5J84_RS02325	COG2814	Major facilitator Superfamily
J5J84_RS02335	COG0656	L-ascorbic acid biosynthetic process
J5J84_RS02340	COG2814	Major facilitator Superfamily
J5J84_RS02345	COG0583	DNA-binding transcription factor activity
J5J84_RS02355	COG3685	Protein conserved in bacteria
J5J84_RS02380	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J5J84_RS02385	COG2814	Major facilitator Superfamily
J5J84_RS02390	COG0655	NAD(P)H dehydrogenase (quinone) activity
J5J84_RS02395	COG0583	DNA-binding transcription factor activity
J5J84_RS02410	COG4774	siderophore transport
J5J84_RS02415	COG4607	ABC-type enterochelin transport system periplasmic component
J5J84_RS02420	COG4604	ABC transporter, ATP-binding protein
J5J84_RS02425	COG4605	iron ion homeostasis
J5J84_RS02430	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5J84_RS02435	COG1132	(ABC) transporter
J5J84_RS02440	COG1132	(ABC) transporter
J5J84_RS02440	COG2375	cellular response to nickel ion
J5J84_RS02445	COG0277	FAD linked oxidase domain protein
J5J84_RS02450	COG1304	FMN binding
J5J84_RS02455	COG2186	Transcriptional regulator
J5J84_RS02475	COG1609	Transcriptional regulator
J5J84_RS02480	COG1522	sequence-specific DNA binding
J5J84_RS02485	COG3844	kynureninase activity
J5J84_RS02490	COG1113	amino acid transport
J5J84_RS02520	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS02525	COG1349	DNA-binding transcription factor activity
J5J84_RS02545	COG0395	ABC-type sugar transport system, permease component
J5J84_RS02550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J5J84_RS02555	COG0861	Integral membrane protein TerC family
J5J84_RS02560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5J84_RS02570	COG1671	Belongs to the UPF0178 family
J5J84_RS02580	COG1418	mRNA catabolic process
J5J84_RS02590	COG4948	Mandelate Racemase Muconate Lactonizing
J5J84_RS02600	COG0477	Major facilitator Superfamily
J5J84_RS02615	COG0154	amidase activity
J5J84_RS02625	COG0583	DNA-binding transcription factor activity
J5J84_RS02650	COG0326	Molecular chaperone. Has ATPase activity
J5J84_RS02655	COG4774	siderophore transport
J5J84_RS02660	COG3128	pkhd-type hydroxylase
J5J84_RS02670	COG3023	N-Acetylmuramoyl-L-alanine amidase
J5J84_RS02685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J5J84_RS02700	COG1652	LysM domain
J5J84_RS02715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5J84_RS02760	COG0583	DNA-binding transcription factor activity
J5J84_RS02765	COG0387	Pfam Sodium calcium exchanger
J5J84_RS02780	COG0477	Major facilitator Superfamily
J5J84_RS02785	COG0235	Class ii aldolase
J5J84_RS02800	COG3391	amine dehydrogenase activity
J5J84_RS02805	COG0590	tRNA wobble adenosine to inosine editing
J5J84_RS02810	COG3257	ureidoglycine aminohydrolase activity
J5J84_RS02815	COG0583	DNA-binding transcription factor activity
J5J84_RS02820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J5J84_RS02825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5J84_RS02825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5J84_RS02835	COG0489	protein tyrosine kinase activity
J5J84_RS02860	COG2081	HI0933 family
J5J84_RS02865	COG0509	glycine decarboxylation via glycine cleavage system
J5J84_RS02875	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J5J84_RS02880	COG1765	OsmC-like protein
J5J84_RS02885	COG3278	Belongs to the heme-copper respiratory oxidase family
J5J84_RS02910	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
J5J84_RS02915	COG0469	pyruvate kinase activity
J5J84_RS02920	COG3193	protein, possibly involved in utilization of glycolate and propanediol
J5J84_RS02930	COG2084	Dehydrogenase
J5J84_RS02935	COG3622	Belongs to the hyi family
J5J84_RS02940	COG3960	tartronate-semialdehyde synthase activity
J5J84_RS02945	COG0583	DNA-binding transcription factor activity
J5J84_RS02955	COG2233	PERMEase
J5J84_RS02960	COG1942	4-Oxalocrotonate Tautomerase
J5J84_RS02965	COG0235	Class ii aldolase
J5J84_RS02975	COG3648	Uricase
J5J84_RS02975	COG3195	allantoin biosynthetic process
J5J84_RS02985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5J84_RS02990	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J5J84_RS03005	COG0438	transferase activity, transferring glycosyl groups
J5J84_RS03015	COG0438	transferase activity, transferring glycosyl groups
J5J84_RS03025	COG0277	FAD linked oxidase domain protein
J5J84_RS03035	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5J84_RS03040	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J5J84_RS03050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_RS03060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J5J84_RS03070	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J5J84_RS03085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5J84_RS03090	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5J84_RS03095	COG0193	aminoacyl-tRNA hydrolase activity
J5J84_RS03105	COG0012	GTP binding
J5J84_RS03110	COG0582	viral genome integration into host DNA
J5J84_RS03125	COG4804	nuclease activity
J5J84_RS03130	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J5J84_RS03150	COG0488	(ABC) transporter
J5J84_RS03165	COG0288	reversible hydration of carbon dioxide
J5J84_RS03170	COG0583	DNA-binding transcription factor activity
J5J84_RS03180	COG4133	protoheme IX ABC transporter activity
J5J84_RS03200	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J5J84_RS03210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5J84_RS03215	COG3088	subunit of a heme lyase
J5J84_RS03220	COG4235	cytochrome complex assembly
J5J84_RS03225	COG0785	Cytochrome C biogenesis protein
J5J84_RS03235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5J84_RS03235	COG2169	Transcriptional regulator
J5J84_RS03255	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5J84_RS03265	COG0411	ABC transporter
J5J84_RS03275	COG1858	cytochrome C peroxidase
J5J84_RS03280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5J84_RS03285	COG1959	2 iron, 2 sulfur cluster binding
J5J84_RS03290	COG2346	COG2346, Truncated hemoglobins
J5J84_RS03295	COG0463	Glycosyl transferase, family 2
J5J84_RS03335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J5J84_RS03340	COG3383	formate dehydrogenase (NAD+) activity
J5J84_RS03355	COG1910	domain protein
J5J84_RS03360	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J5J84_RS03370	COG0303	'Molybdopterin
J5J84_RS03375	COG0521	Mo-molybdopterin cofactor biosynthetic process
J5J84_RS03380	COG0314	molybdopterin synthase activity
J5J84_RS03390	COG0315	cyclic pyranopterin monophosphate synthase activity
J5J84_RS03420	COG0678	peroxiredoxin activity
J5J84_RS03435	COG0697	spore germination
J5J84_RS03440	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5J84_RS03520	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J5J84_RS03525	COG4535	Mg2 and Co2 transporter CorC
J5J84_RS03530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5J84_RS03535	COG1702	phosphate starvation-inducible protein PhoH
J5J84_RS03540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5J84_RS03555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5J84_RS03560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5J84_RS03565	COG1862	Preprotein translocase
J5J84_RS03570	COG0343	queuine tRNA-ribosyltransferase activity
J5J84_RS03575	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5J84_RS03580	COG2027	D-alanyl-D-alanine carboxypeptidase
J5J84_RS03585	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J5J84_RS03595	COG4575	ribosome binding
J5J84_RS03610	COG0583	DNA-binding transcription factor activity
J5J84_RS03625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5J84_RS03640	COG0154	amidase activity
J5J84_RS03650	COG0477	Major facilitator Superfamily
J5J84_RS03665	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J5J84_RS03675	COG0436	Aminotransferase
J5J84_RS03685	COG0280	phosphate acetyltransferase
J5J84_RS03685	COG0281	malic enzyme
J5J84_RS03695	COG2732	(Barnase) inhibitor
J5J84_RS03700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J5J84_RS03705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J5J84_RS03710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J5J84_RS03715	COG0126	phosphoglycerate kinase activity
J5J84_RS03740	COG0521	Mo-molybdopterin cofactor biosynthetic process
J5J84_RS03750	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5J84_RS03755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J5J84_RS03760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J5J84_RS03765	COG0009	L-threonylcarbamoyladenylate synthase
J5J84_RS03770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5J84_RS03775	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_RS03775	COG2030	dehydratase
J5J84_RS03780	COG1960	acyl-CoA dehydrogenase activity
J5J84_RS03790	COG0405	Gamma-glutamyltransferase
J5J84_RS03800	COG0579	oxidoreductase
J5J84_RS03805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5J84_RS03810	COG0259	pyridoxamine-phosphate oxidase activity
J5J84_RS03820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J5J84_RS03835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5J84_RS03840	COG1215	transferase activity, transferring glycosyl groups
J5J84_RS03850	COG0488	(ABC) transporter
J5J84_RS03870	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J5J84_RS03875	COG2894	cell division
J5J84_RS03885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5J84_RS03890	COG1271	oxidase subunit
J5J84_RS03895	COG1294	oxidase, subunit
J5J84_RS03900	COG0038	chloride channel
J5J84_RS03910	COG0514	ATP-dependent DNA helicase (RecQ)
J5J84_RS03915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5J84_RS03920	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5J84_RS03925	COG0633	Ferredoxin
J5J84_RS03930	COG0488	(ABC) transporter
J5J84_RS03940	COG2001	Belongs to the MraZ family
J5J84_RS03945	COG0275	rRNA processing
J5J84_RS03950	COG3116	cell division
J5J84_RS03960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5J84_RS03965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5J84_RS03970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5J84_RS03980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5J84_RS03985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5J84_RS03990	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5J84_RS03995	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J5J84_RS04010	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J5J84_RS04020	COG1196	nuclear chromosome segregation
J5J84_RS04020	COG0741	lytic transglycosylase activity
J5J84_RS04020	COG0739	heme binding
J5J84_RS04025	COG0653	protein targeting
J5J84_RS04035	COG2239	Acts as a magnesium transporter
J5J84_RS04045	COG1473	amidohydrolase
J5J84_RS04050	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_RS04060	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J5J84_RS04060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_RS04075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J5J84_RS04080	COG2011	ABC-type metal ion transport system permease component
J5J84_RS04090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_RS04095	COG0765	amino acid transport
J5J84_RS04100	COG1126	abc transporter atp-binding protein
J5J84_RS04110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5J84_RS04125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5J84_RS04130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5J84_RS04135	COG0700	Nucleoside recognition
J5J84_RS04150	COG0204	Acyl-transferase
J5J84_RS04155	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J5J84_RS04160	COG0751	glycine-tRNA ligase activity
J5J84_RS04165	COG0752	glycyl-tRNA synthetase alpha subunit
J5J84_RS04175	COG1024	Enoyl-CoA hydratase
J5J84_RS04185	COG1309	transcriptional regulator
J5J84_RS04195	COG2814	Major facilitator Superfamily
J5J84_RS04210	COG1573	uracil-dna glycosylase
J5J84_RS04215	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5J84_RS04220	COG0617	tRNA 3'-terminal CCA addition
J5J84_RS04230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5J84_RS04235	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5J84_RS04240	COG1953	Uracil, thiamine, allantoin
J5J84_RS04245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5J84_RS04250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5J84_RS04255	COG0586	Pfam SNARE associated Golgi protein
J5J84_RS04260	COG0860	N-Acetylmuramoyl-L-alanine amidase
J5J84_RS04265	COG0802	atpase or kinase
J5J84_RS04275	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS04280	COG0280	phosphate acetyltransferase
J5J84_RS04280	COG0281	malic enzyme
J5J84_RS04285	COG0583	DNA-binding transcription factor activity
J5J84_RS04290	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_RS04295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5J84_RS04315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_RS04340	COG1733	regulation of RNA biosynthetic process
J5J84_RS04345	COG2910	NAD(P)H-binding
J5J84_RS04355	COG2223	nitrite transmembrane transporter activity
J5J84_RS04360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5J84_RS04365	COG4974	Belongs to the 'phage' integrase family
J5J84_RS04370	COG0725	ABC transporter, periplasmic molybdate-binding protein
J5J84_RS04375	COG4149	molybdate abc transporter
J5J84_RS04380	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5J84_RS04395	COG1074	ATP-dependent DNA helicase activity
J5J84_RS04430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_RS04450	COG3391	amine dehydrogenase activity
J5J84_RS04455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J5J84_RS04460	COG0505	Belongs to the CarA family
J5J84_RS04465	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5J84_RS04485	COG2233	PERMEase
J5J84_RS04490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5J84_RS04495	COG1534	Rna-binding protein
J5J84_RS04500	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J5J84_RS04505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5J84_RS04515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5J84_RS04525	COG0248	Ppx GppA phosphatase
J5J84_RS04530	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5J84_RS04550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5J84_RS04555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J5J84_RS04605	COG1231	oxidoreductase activity
J5J84_RS04610	COG2010	Cytochrome c
J5J84_RS04615	COG2323	membrane
J5J84_RS04625	COG1368	sulfuric ester hydrolase activity
J5J84_RS04655	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5J84_RS04660	COG3327	negative regulation of DNA-templated transcription, initiation
J5J84_RS04665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5J84_RS04680	COG0009	L-threonylcarbamoyladenylate synthase
J5J84_RS04685	COG1994	Peptidase M50
J5J84_RS04690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5J84_RS04695	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J5J84_RS04710	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5J84_RS04720	COG0156	8-amino-7-oxononanoate synthase activity
J5J84_RS04725	COG2124	cytochrome p450
J5J84_RS04735	COG3135	benzoate transporter
J5J84_RS04740	COG2850	peptidyl-arginine hydroxylation
J5J84_RS04745	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5J84_RS04750	COG3391	amine dehydrogenase activity
J5J84_RS04765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5J84_RS04770	COG1136	(ABC) transporter
J5J84_RS04770	COG0577	efflux transmembrane transporter activity
J5J84_RS04775	COG1538	Outer membrane efflux protein
J5J84_RS04780	COG0363	glucosamine-6-phosphate deaminase activity
J5J84_RS04785	COG1132	(ABC) transporter
J5J84_RS04795	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS04805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5J84_RS04815	COG0668	transmembrane transport
J5J84_RS04825	COG0604	alcohol dehydrogenase
J5J84_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS04825	COG3321	synthase
J5J84_RS04860	COG0154	amidase activity
J5J84_RS04865	COG2031	fatty acid transporter
J5J84_RS04880	COG0483	inositol monophosphate 1-phosphatase activity
J5J84_RS04885	COG1253	flavin adenine dinucleotide binding
J5J84_RS04890	COG1968	undecaprenyl-diphosphatase activity
J5J84_RS04915	COG0215	cysteine-tRNA ligase activity
J5J84_RS04925	COG0825	malonyl-CoA metabolic process
J5J84_RS04930	COG0037	tRNA processing
J5J84_RS04955	COG0330	HflC and HflK could
J5J84_RS04980	COG4208	sulfate ABC transporter
J5J84_RS04985	COG3842	ATPase activity
J5J84_RS04995	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J5J84_RS05025	COG1304	FMN binding
J5J84_RS05030	COG0435	Glutathione S-transferase
J5J84_RS05035	COG0655	NAD(P)H dehydrogenase (quinone) activity
J5J84_RS05055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J5J84_RS05060	COG2363	Small membrane protein
J5J84_RS05065	COG0598	Magnesium transport protein CorA
J5J84_RS05070	COG1960	acyl-CoA dehydrogenase activity
J5J84_RS05090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5J84_RS05095	COG4172	Belongs to the ABC transporter superfamily
J5J84_RS05105	COG3284	Transcriptional regulator
J5J84_RS05110	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_RS05115	COG1454	alcohol dehydrogenase
J5J84_RS05135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_RS05145	COG0183	Belongs to the thiolase family
J5J84_RS05150	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_RS05160	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS05165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5J84_RS05190	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_RS05220	COG3829	transcription factor binding
J5J84_RS05225	COG0477	Major facilitator Superfamily
J5J84_RS05235	COG0039	L-malate dehydrogenase activity
J5J84_RS05240	COG2188	Transcriptional regulator
J5J84_RS05245	COG2009	succinate dehydrogenase
J5J84_RS05255	COG1053	succinate dehydrogenase
J5J84_RS05260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J5J84_RS05265	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J5J84_RS05270	COG0372	Belongs to the citrate synthase family
J5J84_RS05275	COG2186	Transcriptional regulator
J5J84_RS05280	COG1620	l-lactate permease
J5J84_RS05285	COG0281	malic enzyme
J5J84_RS05285	COG0280	phosphate acetyltransferase
J5J84_RS05290	COG0567	Dehydrogenase, E1 component
J5J84_RS05295	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5J84_RS05300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5J84_RS05305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J5J84_RS05325	COG2183	response to ionizing radiation
J5J84_RS05330	COG1199	ATP-dependent helicase activity
J5J84_RS05340	COG1733	regulation of RNA biosynthetic process
J5J84_RS05365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_RS05375	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5J84_RS05375	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_RS05390	COG0564	pseudouridine synthase activity
J5J84_RS05400	COG3243	poly(R)-hydroxyalkanoic acid synthase
J5J84_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS05410	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
J5J84_RS05435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J5J84_RS05440	COG1187	pseudouridine synthase activity
J5J84_RS05445	COG0779	Required for maturation of 30S ribosomal subunits
J5J84_RS05450	COG0195	Participates in both transcription termination and antitermination
J5J84_RS05450	COG2251	uridine kinase activity
J5J84_RS05455	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5J84_RS05460	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5J84_RS05465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5J84_RS05470	COG1217	gtp-binding protein TYPA
J5J84_RS05475	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5J84_RS05485	COG4160	amino acid transport
J5J84_RS05490	COG4215	(ABC) transporter
J5J84_RS05510	COG1283	sodium-dependent phosphate transmembrane transporter activity
J5J84_RS05520	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J5J84_RS05535	COG0456	acetyltransferase
J5J84_RS05540	COG0501	Belongs to the peptidase M48B family
J5J84_RS05555	COG1722	exodeoxyribonuclease VII activity
J5J84_RS05560	COG0142	geranyltranstransferase activity
J5J84_RS05570	COG1469	GTP cyclohydrolase I activity
J5J84_RS05575	COG0360	Binds together with S18 to 16S ribosomal RNA
J5J84_RS05580	COG2965	DNA replication, synthesis of RNA primer
J5J84_RS05585	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J5J84_RS05595	COG0305	Participates in initiation and elongation during chromosome replication
J5J84_RS05605	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5J84_RS05610	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J5J84_RS05615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J5J84_RS05625	COG0436	Aminotransferase
J5J84_RS05640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5J84_RS05645	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
J5J84_RS05650	COG1562	ergosterol biosynthetic process
J5J84_RS05655	COG1562	ergosterol biosynthetic process
J5J84_RS05660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5J84_RS05665	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS05690	COG3842	ATPase activity
J5J84_RS05695	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5J84_RS05700	COG1177	transmembrane transport
J5J84_RS05705	COG1393	Belongs to the ArsC family
J5J84_RS05710	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J5J84_RS05715	COG0704	Plays a role in the regulation of phosphate uptake
J5J84_RS05720	COG4251	negative regulation of phosphorylation
J5J84_RS05720	COG5001	Diguanylate cyclase
J5J84_RS05720	COG2203	Gaf domain
J5J84_RS05720	COG3706	GGDEF domain
J5J84_RS05725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J5J84_RS05730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5J84_RS05730	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J5J84_RS05735	COG1643	Atp-dependent helicase
J5J84_RS05745	COG0438	transferase activity, transferring glycosyl groups
J5J84_RS05750	COG0726	polysaccharide deacetylase
J5J84_RS05790	COG1132	(ABC) transporter
J5J84_RS05840	COG2186	Transcriptional regulator
J5J84_RS05845	COG0277	FAD linked oxidase domain protein
J5J84_RS05850	COG0277	FAD linked oxidase domain protein
J5J84_RS05855	COG0247	lactate metabolic process
J5J84_RS05880	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_RS05925	COG0628	permease
J5J84_RS05930	COG1283	sodium-dependent phosphate transmembrane transporter activity
J5J84_RS05945	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_RS05955	COG0697	spore germination
J5J84_RS05975	COG3094	Invasion gene expression up-regulator, SirB
J5J84_RS05985	COG0640	Transcriptional regulator
J5J84_RS06010	COG0659	secondary active sulfate transmembrane transporter activity
J5J84_RS06015	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5J84_RS06025	COG2314	TM2 domain
J5J84_RS06030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J5J84_RS06035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J5J84_RS06040	COG0791	NLP P60 protein
J5J84_RS06060	COG1360	Flagellar Motor Protein
J5J84_RS06070	COG0835	chemotaxis
J5J84_RS06075	COG0840	transmembrane signaling receptor activity
J5J84_RS06080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J5J84_RS06090	COG0745	RESPONSE REGULATOR receiver
J5J84_RS06095	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J5J84_RS06100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J5J84_RS06105	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J5J84_RS06125	COG1120	ATPase activity
J5J84_RS06160	COG3486	L-lysine 6-monooxygenase (NADPH) activity
J5J84_RS06180	COG1815	bacterial-type flagellum-dependent cell motility
J5J84_RS06185	COG1558	bacterial-type flagellum-dependent cell motility
J5J84_RS06190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J5J84_RS06230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5J84_RS06245	COG0840	transmembrane signaling receptor activity
J5J84_RS06255	COG2176	DNA-directed DNA polymerase activity
J5J84_RS06265	COG1987	bacterial-type flagellum assembly
J5J84_RS06280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J5J84_RS06290	COG1580	Controls the rotational direction of flagella during chemotaxis
J5J84_RS06305	COG1157	protein secretion by the type III secretion system
J5J84_RS06320	COG1766	The M ring may be actively involved in energy transduction
J5J84_RS06325	COG1677	Flagellar hook-basal body complex protein FliE
J5J84_RS06330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J5J84_RS06355	COG1334	flagellar protein FlaG
J5J84_RS06360	COG1191	sigma factor activity
J5J84_RS06415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5J84_RS06435	COG2733	membrane
J5J84_RS06440	COG0840	transmembrane signaling receptor activity
J5J84_RS06445	COG0840	transmembrane signaling receptor activity
J5J84_RS06470	COG2610	gluconate transmembrane transporter activity
J5J84_RS06485	COG4974	Belongs to the 'phage' integrase family
J5J84_RS06545	COG4128	Pfam Zonular occludens toxin
J5J84_RS06560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J5J84_RS06570	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J5J84_RS06575	COG3657	addiction module killer protein
J5J84_RS06580	COG4521	taurine ABC transporter
J5J84_RS06585	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J5J84_RS06590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_RS06595	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS06600	COG0583	DNA-binding transcription factor activity
J5J84_RS06630	COG2824	Alkylphosphonate utilization operon protein PhnA
J5J84_RS06650	COG1113	amino acid transport
J5J84_RS06665	COG0583	DNA-binding transcription factor activity
J5J84_RS06670	COG3755	Protein conserved in bacteria
J5J84_RS06710	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5J84_RS06735	COG1278	Cold shock
J5J84_RS06740	COG0642	Histidine kinase
J5J84_RS06750	COG3278	Belongs to the heme-copper respiratory oxidase family
J5J84_RS06760	COG2863	cytochrome
J5J84_RS06765	COG3258	Cytochrome c
J5J84_RS06780	COG4774	siderophore transport
J5J84_RS06815	COG0025	NhaP-type Na H and K H
J5J84_RS06830	COG1289	transmembrane transporter activity
J5J84_RS06835	COG2252	PERMEase
J5J84_RS06855	COG1999	signal sequence binding
J5J84_RS06865	COG0069	glutamate synthase activity
J5J84_RS06875	COG1846	Transcriptional regulator
J5J84_RS06885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5J84_RS06925	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS06935	COG3264	Mechanosensitive ion channel
J5J84_RS06935	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J5J84_RS06940	COG1511	domain protein
J5J84_RS06940	COG3264	Mechanosensitive ion channel
J5J84_RS06945	COG0477	Major facilitator Superfamily
J5J84_RS06960	COG1396	sequence-specific DNA binding
J5J84_RS06965	COG3437	response regulator, receiver
J5J84_RS06970	COG0784	Response regulator, receiver
J5J84_RS06970	COG2198	Histidine kinase
J5J84_RS06970	COG2205	protein histidine kinase activity
J5J84_RS06975	COG2239	Acts as a magnesium transporter
J5J84_RS06985	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J5J84_RS06990	COG1490	D-aminoacyl-tRNA deacylase activity
J5J84_RS07005	COG0456	acetyltransferase
J5J84_RS07015	COG0501	Belongs to the peptidase M48B family
J5J84_RS07020	COG2814	Major facilitator Superfamily
J5J84_RS07075	COG2199	diguanylate cyclase activity
J5J84_RS07090	COG1522	sequence-specific DNA binding
J5J84_RS07095	COG0626	cystathionine gamma-synthase activity
J5J84_RS07105	COG0494	nUDIX hydrolase
J5J84_RS07110	COG2832	Protein of unknown function (DUF454)
J5J84_RS07120	COG0137	argininosuccinate synthase activity
J5J84_RS07125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J5J84_RS07130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5J84_RS07150	COG1609	Transcriptional regulator
J5J84_RS07160	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5J84_RS07170	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J5J84_RS07175	COG2205	protein histidine kinase activity
J5J84_RS07180	COG0745	RESPONSE REGULATOR receiver
J5J84_RS07185	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5J84_RS07195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5J84_RS07200	COG0268	Binds directly to 16S ribosomal RNA
J5J84_RS07205	COG0728	peptidoglycan biosynthetic process
J5J84_RS07215	COG0563	adenylate kinase activity
J5J84_RS07220	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5J84_RS07225	COG2835	tetraacyldisaccharide 4'-kinase activity
J5J84_RS07230	COG1663	tetraacyldisaccharide 4'-kinase activity
J5J84_RS07235	COG0848	biopolymer transport protein
J5J84_RS07240	COG0811	peptide transport
J5J84_RS07245	COG1570	exodeoxyribonuclease VII activity
J5J84_RS07250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J5J84_RS07260	COG0183	Belongs to the thiolase family
J5J84_RS07270	COG1278	Cold shock
J5J84_RS07275	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J5J84_RS07280	COG0542	response to heat
J5J84_RS07285	COG2995	paraquat-inducible protein a
J5J84_RS07290	COG3008	intermembrane lipid transfer
J5J84_RS07290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5J84_RS07310	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5J84_RS07345	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
J5J84_RS07350	COG0756	dUTP diphosphatase activity
J5J84_RS07360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J5J84_RS07365	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5J84_RS07370	COG0196	riboflavin kinase activity
J5J84_RS07375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5J84_RS07380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J5J84_RS07380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5J84_RS07390	COG0210	DNA helicase
J5J84_RS07445	COG0488	(ABC) transporter
J5J84_RS07450	COG2890	protein-(glutamine-N5) methyltransferase activity
J5J84_RS07455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5J84_RS07460	COG2171	N-acyltransferase activity
J5J84_RS07470	COG2207	Transcriptional regulator
J5J84_RS07480	COG3273	potassium ion transport
J5J84_RS07480	COG0471	metal ion transport
J5J84_RS07665	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
J5J84_RS07705	COG0740	serine-type endopeptidase activity
J5J84_RS07840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_RS07845	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5J84_RS07850	COG0740	serine-type endopeptidase activity
J5J84_RS07860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J5J84_RS07870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5J84_RS07880	COG0556	nucleotide-excision repair
J5J84_RS07885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5J84_RS07895	COG1104	cysteine desulfurase activity
J5J84_RS07905	COG0316	Belongs to the HesB IscA family
J5J84_RS07920	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J5J84_RS07925	COG4221	oxidoreductase activity
J5J84_RS07935	COG0840	transmembrane signaling receptor activity
J5J84_RS07940	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5J84_RS07945	COG0697	spore germination
J5J84_RS07950	COG0385	Bile acid
J5J84_RS07960	COG2831	hemolysin activation secretion protein
J5J84_RS07965	COG3210	domain, Protein
J5J84_RS07995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5J84_RS08010	COG1136	(ABC) transporter
J5J84_RS08015	COG0084	hydrolase, TatD family'
J5J84_RS08030	COG0613	PHP domain protein
J5J84_RS08040	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5J84_RS08040	COG0047	phosphoribosylformylglycinamidine synthase activity
J5J84_RS08065	COG0519	Catalyzes the synthesis of GMP from XMP
J5J84_RS08065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5J84_RS08085	COG1196	nuclear chromosome segregation
J5J84_RS08095	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J5J84_RS08105	COG3311	Transcriptional regulator
J5J84_RS08120	COG2076	Multidrug Resistance protein
J5J84_RS08125	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS08130	COG0583	DNA-binding transcription factor activity
J5J84_RS08145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J5J84_RS08155	COG1960	acyl-CoA dehydrogenase activity
J5J84_RS08160	COG0523	cobalamin synthesis protein
J5J84_RS08165	COG1469	GTP cyclohydrolase I activity
J5J84_RS08170	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5J84_RS08180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J5J84_RS08185	COG0735	belongs to the Fur family
J5J84_RS08190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5J84_RS08210	COG0745	RESPONSE REGULATOR receiver
J5J84_RS08225	COG1942	4-Oxalocrotonate Tautomerase
J5J84_RS08240	COG2070	2-Nitropropane dioxygenase
J5J84_RS08265	COG1309	transcriptional regulator
J5J84_RS08280	COG0625	glutathione transferase activity
J5J84_RS08285	COG0583	DNA-binding transcription factor activity
J5J84_RS08305	COG0625	glutathione transferase activity
J5J84_RS08310	COG0740	serine-type endopeptidase activity
J5J84_RS08360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_RS08370	COG1960	acyl-CoA dehydrogenase activity
J5J84_RS08395	COG0640	Transcriptional regulator
J5J84_RS08420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5J84_RS08445	COG3485	protocatechuate 3,4-dioxygenase
J5J84_RS08455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J5J84_RS08460	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5J84_RS08470	COG3135	benzoate transporter
J5J84_RS08480	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J5J84_RS08490	COG1136	(ABC) transporter
J5J84_RS08500	COG2197	response regulator
J5J84_RS08505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J5J84_RS08530	COG1846	Transcriptional regulator
J5J84_RS08535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_RS08540	COG2271	Major facilitator Superfamily
J5J84_RS08550	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5J84_RS08560	COG0697	spore germination
J5J84_RS08590	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5J84_RS08595	COG0667	Aldo Keto reductase
J5J84_RS08610	COG0582	viral genome integration into host DNA
J5J84_RS08670	COG1272	protein, Hemolysin III
J5J84_RS08675	COG3422	double-strand break repair
J5J84_RS08700	COG0765	amino acid transport
J5J84_RS08705	COG0765	amino acid transport
J5J84_RS08710	COG1126	abc transporter atp-binding protein
J5J84_RS08765	COG2871	sodium ion transport
J5J84_RS08795	COG2814	Major facilitator Superfamily
J5J84_RS08800	COG1280	lysine exporter protein (LysE YggA)
J5J84_RS08820	COG0402	S-adenosylhomocysteine deaminase activity
J5J84_RS08845	COG0330	HflC and HflK could
J5J84_RS08850	COG1585	Membrane protein implicated in regulation of membrane protease activity
J5J84_RS08855	COG2226	methyltransferase
J5J84_RS08865	COG3042	response to heat
J5J84_RS08875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5J84_RS08895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J5J84_RS08900	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J5J84_RS08915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5J84_RS08920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5J84_RS08950	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5J84_RS08955	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J5J84_RS08960	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J5J84_RS08965	COG0072	phenylalanine-tRNA ligase activity
J5J84_RS08965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5J84_RS08980	COG2833	Protein of unknown function (DUF455)
J5J84_RS08990	COG5265	(ABC) transporter
J5J84_RS08995	COG1959	2 iron, 2 sulfur cluster binding
J5J84_RS09000	COG0719	Fe-S assembly protein
J5J84_RS09005	COG0396	ATPase activity
J5J84_RS09010	COG0719	Fe-S assembly protein
J5J84_RS09020	COG0822	iron-sulfur transferase activity
J5J84_RS09025	COG2151	metal-sulfur cluster biosynthetic enzyme
J5J84_RS09040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5J84_RS09055	COG4197	protein conserved in bacteria, prophage-related
J5J84_RS09090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5J84_RS09095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5J84_RS09105	COG0745	RESPONSE REGULATOR receiver
J5J84_RS09145	COG3048	D-serine ammonia-lyase activity
J5J84_RS09150	COG3258	Cytochrome c
J5J84_RS09165	COG3949	Membrane
J5J84_RS09175	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5J84_RS09190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5J84_RS09195	COG0569	domain protein
J5J84_RS09200	COG1902	pentaerythritol trinitrate reductase activity
J5J84_RS09210	COG1610	YqeY-like protein
J5J84_RS09215	COG0587	DNA-directed DNA polymerase activity
J5J84_RS09250	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS09255	COG0583	DNA-binding transcription factor activity
J5J84_RS09260	COG1686	Belongs to the peptidase S11 family
J5J84_RS09275	COG1360	Flagellar Motor Protein
J5J84_RS09285	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS09295	COG4221	oxidoreductase activity
J5J84_RS09305	COG0307	riboflavin synthase, alpha
J5J84_RS09350	COG2233	PERMEase
J5J84_RS09355	COG0071	Belongs to the small heat shock protein (HSP20) family
J5J84_RS09360	COG1473	amidohydrolase
J5J84_RS09400	COG2816	NAD+ diphosphatase activity
J5J84_RS09405	COG1561	YicC-like family, N-terminal region
J5J84_RS09420	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J5J84_RS09425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5J84_RS09430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5J84_RS09435	COG0174	glutamine synthetase
J5J84_RS09440	COG2153	protein acetylation
J5J84_RS09460	COG3842	ATPase activity
J5J84_RS09465	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J5J84_RS09470	COG1840	ABC-type Fe3 transport system, periplasmic component
J5J84_RS09485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5J84_RS09495	COG0783	Belongs to the Dps family
J5J84_RS09505	COG3842	ATPase activity
J5J84_RS09510	COG0395	ABC-type sugar transport system, permease component
J5J84_RS09515	COG1175	transmembrane transport
J5J84_RS09520	COG1653	transport
J5J84_RS09535	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5J84_RS09555	COG0625	glutathione transferase activity
J5J84_RS09565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5J84_RS09570	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS09575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J5J84_RS09580	COG0114	fumarate hydratase activity
J5J84_RS09585	COG2133	pyrroloquinoline quinone binding
J5J84_RS09590	COG2226	methyltransferase
J5J84_RS09595	COG0589	response to stress
J5J84_RS09600	COG4654	Cytochrome c, class I
J5J84_RS09605	COG2207	Transcriptional regulator
J5J84_RS09610	COG0235	Class ii aldolase
J5J84_RS09620	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_RS09625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_RS09630	COG2807	transmembrane transport
J5J84_RS09640	COG0583	DNA-binding transcription factor activity
J5J84_RS09670	COG0583	DNA-binding transcription factor activity
J5J84_RS09675	COG4974	Belongs to the 'phage' integrase family
J5J84_RS09690	COG2132	Multicopper oxidase
J5J84_RS09695	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J5J84_RS09710	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS09735	COG3038	cytochrome b561
J5J84_RS09745	COG2353	YceI-like domain
J5J84_RS09750	COG1393	Belongs to the ArsC family
J5J84_RS09755	COG0625	glutathione transferase activity
J5J84_RS09780	COG0084	hydrolase, TatD family'
J5J84_RS09785	COG0470	DNA polymerase III
J5J84_RS09795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J5J84_RS09815	COG1960	acyl-CoA dehydrogenase activity
J5J84_RS09820	COG2914	Belongs to the UPF0125 (RnfH) family
J5J84_RS09825	COG2867	negative regulation of translational initiation
J5J84_RS09830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5J84_RS09835	COG1252	NADH dehydrogenase
J5J84_RS09860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5J84_RS09865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J5J84_RS09870	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5J84_RS09880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5J84_RS09885	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5J84_RS09895	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5J84_RS09905	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5J84_RS09910	COG0575	Belongs to the CDS family
J5J84_RS09915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J5J84_RS09920	COG0233	cytoplasmic translational termination
J5J84_RS09925	COG0528	UMP kinase activity
J5J84_RS09930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5J84_RS09935	COG0052	Belongs to the universal ribosomal protein uS2 family
J5J84_RS09940	COG0024	Methionine aminopeptidase
J5J84_RS09945	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J5J84_RS09960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J5J84_RS09970	COG1286	toxin biosynthetic process
J5J84_RS09980	COG0285	dihydrofolate synthase activity
J5J84_RS09985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5J84_RS09990	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5J84_RS09995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J5J84_RS10005	COG4566	intracellular signal transduction
J5J84_RS10010	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5J84_RS10020	COG1999	signal sequence binding
J5J84_RS10025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5J84_RS10030	COG0640	Transcriptional regulator
J5J84_RS10045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_RS10050	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5J84_RS10055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_RS10060	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J5J84_RS10065	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS10070	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS10090	COG0183	Belongs to the thiolase family
J5J84_RS10110	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5J84_RS10120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5J84_RS10125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5J84_RS10130	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
J5J84_RS10150	COG0183	Belongs to the thiolase family
J5J84_RS10155	COG0183	Belongs to the thiolase family
J5J84_RS10165	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J5J84_RS10200	COG0194	GDP metabolic process
J5J84_RS10205	COG1758	RNA polymerase activity
J5J84_RS10210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J5J84_RS10220	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J5J84_RS10225	COG0739	heme binding
J5J84_RS10230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5J84_RS10235	COG0584	glycerophosphoryl diester phosphodiesterase
J5J84_RS10240	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J5J84_RS10245	COG1187	pseudouridine synthase activity
J5J84_RS10250	COG3161	chorismate lyase activity
J5J84_RS10255	COG2814	Major facilitator Superfamily
J5J84_RS10260	COG0656	L-ascorbic acid biosynthetic process
J5J84_RS10270	COG0668	transmembrane transport
J5J84_RS10275	COG0165	Argininosuccinate lyase
J5J84_RS10290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_RS10300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J5J84_RS10310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J5J84_RS10315	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J5J84_RS10320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J5J84_RS10325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5J84_RS10330	COG2252	PERMEase
J5J84_RS10335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5J84_RS10355	COG0488	(ABC) transporter
J5J84_RS10360	COG1619	proteins homologs of microcin C7 resistance protein MccF
J5J84_RS10370	COG1131	(ABC) transporter
J5J84_RS10375	COG0842	Transport permease protein
J5J84_RS10380	COG0840	transmembrane signaling receptor activity
J5J84_RS10385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_RS10385	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5J84_RS10390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5J84_RS10395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_RS10400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_RS10410	COG2022	thiamine diphosphate biosynthetic process
J5J84_RS10430	COG1414	Transcriptional regulator
J5J84_RS10440	COG0730	response to heat
J5J84_RS10450	COG1666	GTP binding
J5J84_RS10455	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_RS10460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5J84_RS10465	COG0519	Catalyzes the synthesis of GMP from XMP
J5J84_RS10465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5J84_RS10470	COG2207	Transcriptional regulator
J5J84_RS10480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5J84_RS10485	COG0135	phosphoribosylanthranilate isomerase activity
J5J84_RS10490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_RS10500	COG0101	tRNA pseudouridine synthase activity
J5J84_RS10510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5J84_RS10535	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J5J84_RS10545	COG4566	intracellular signal transduction
J5J84_RS10560	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5J84_RS10565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J5J84_RS10575	COG1295	ribonuclease BN
J5J84_RS10585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5J84_RS10615	COG4964	Belongs to the GSP D family
J5J84_RS10660	COG2959	enzyme of heme biosynthesis
J5J84_RS10670	COG0181	hydroxymethylbilane synthase activity
J5J84_RS10675	COG0861	Integral membrane protein TerC family
J5J84_RS10680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J5J84_RS10685	COG0045	succinate-CoA ligase (ADP-forming) activity
J5J84_RS10695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J5J84_RS10700	COG0583	DNA-binding transcription factor activity
J5J84_RS10705	COG2137	regulation of response to DNA damage stimulus
J5J84_RS10710	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J5J84_RS10725	COG0477	Major facilitator Superfamily
J5J84_RS10740	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_RS10745	COG1024	Enoyl-CoA hydratase
J5J84_RS10750	COG3162	membrane
J5J84_RS10765	COG0540	Belongs to the ATCase OTCase family
J5J84_RS10780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5J84_RS10795	COG2070	2-Nitropropane dioxygenase
J5J84_RS10805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J5J84_RS10805	COG2111	Na H antiporter
J5J84_RS10810	COG1006	Multisubunit Na H antiporter MnhC subunit
J5J84_RS10815	COG0651	ATP synthesis coupled electron transport
J5J84_RS10825	COG2212	antiporter activity
J5J84_RS10840	COG0477	Major facilitator Superfamily
J5J84_RS10865	COG3158	transport of potassium into the cell
J5J84_RS10870	COG0642	Histidine kinase
J5J84_RS10895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5J84_RS10900	COG4208	sulfate ABC transporter
J5J84_RS10905	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J5J84_RS10910	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J5J84_RS10925	COG1278	Cold shock
J5J84_RS10940	COG1648	precorrin-2 dehydrogenase activity
J5J84_RS10940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5J84_RS10970	COG0535	radical SAM domain protein
J5J84_RS10975	COG1648	precorrin-2 dehydrogenase activity
J5J84_RS10975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5J84_RS10985	COG2010	Cytochrome c
J5J84_RS10990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_RS10995	COG0626	cystathionine gamma-synthase activity
J5J84_RS11000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5J84_RS11005	COG0557	exoribonuclease II activity
J5J84_RS11025	COG0765	amino acid transport
J5J84_RS11030	COG0765	amino acid transport
J5J84_RS11035	COG1126	abc transporter atp-binding protein
J5J84_RS11050	COG1850	ribulose-bisphosphate carboxylase activity
J5J84_RS11070	COG2375	cellular response to nickel ion
J5J84_RS11085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_RS11100	COG0583	DNA-binding transcription factor activity
J5J84_RS11105	COG3842	ATPase activity
J5J84_RS11110	COG1175	transmembrane transport
J5J84_RS11115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5J84_RS11120	COG1840	ABC-type Fe3 transport system, periplasmic component
J5J84_RS11140	COG0412	Dienelactone hydrolase
J5J84_RS11145	COG3530	Putative quorum-sensing-regulated virulence factor
J5J84_RS11150	COG0625	glutathione transferase activity
J5J84_RS11155	COG1741	Belongs to the pirin family
J5J84_RS11165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5J84_RS11170	COG2814	Major facilitator Superfamily
J5J84_RS11175	COG2807	transmembrane transport
J5J84_RS11180	COG2207	Transcriptional regulator
J5J84_RS11185	COG3135	benzoate transporter
J5J84_RS11210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J5J84_RS11220	COG0402	S-adenosylhomocysteine deaminase activity
J5J84_RS11230	COG0745	RESPONSE REGULATOR receiver
J5J84_RS11235	COG2205	protein histidine kinase activity
J5J84_RS11250	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5J84_RS11255	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J5J84_RS11260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5J84_RS11270	COG0330	HflC and HflK could
J5J84_RS11275	COG0330	HflC and HflK could
J5J84_RS11280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5J84_RS11285	COG1923	regulation of RNA biosynthetic process
J5J84_RS11295	COG1160	GTP binding
J5J84_RS11300	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5J84_RS11305	COG2976	Protein conserved in bacteria
J5J84_RS11325	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5J84_RS11330	COG0105	UTP biosynthetic process
J5J84_RS11340	COG0583	DNA-binding transcription factor activity
J5J84_RS11345	COG0697	spore germination
J5J84_RS11350	COG0336	Belongs to the RNA methyltransferase TrmD family
J5J84_RS11360	COG0228	four-way junction DNA binding
J5J84_RS11365	COG0425	Belongs to the sulfur carrier protein TusA family
J5J84_RS11370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5J84_RS11385	COG2351	hydroxyisourate hydrolase activity
J5J84_RS11420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_RS11445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5J84_RS11450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5J84_RS11475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5J84_RS11480	COG0601	transmembrane transport
J5J84_RS11510	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J5J84_RS11515	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5J84_RS11520	COG0542	response to heat
J5J84_RS11525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5J84_RS11540	COG0348	domain, Protein
J5J84_RS11560	COG3278	Belongs to the heme-copper respiratory oxidase family
J5J84_RS11570	COG2217	Heavy metal translocating P-type atpase
J5J84_RS11575	COG2224	Isocitrate lyase
J5J84_RS11580	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5J84_RS11580	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5J84_RS11600	COG1472	Belongs to the glycosyl hydrolase 3 family
J5J84_RS11605	COG0736	holo-[acyl-carrier-protein] synthase activity
J5J84_RS11615	COG2050	protein possibly involved in aromatic compounds catabolism
J5J84_RS11620	COG1024	Enoyl-CoA hydratase
J5J84_RS11625	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_RS11630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J5J84_RS11635	COG2151	metal-sulfur cluster biosynthetic enzyme
J5J84_RS11640	COG3396	Phenylacetate-CoA oxygenase
J5J84_RS11645	COG3460	Phenylacetate-CoA oxygenase
J5J84_RS11650	COG3396	Phenylacetate-CoA oxygenase
J5J84_RS11655	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J5J84_RS11660	COG0501	Belongs to the peptidase M48B family
J5J84_RS11665	COG1162	GTPase activity
J5J84_RS11675	COG0335	large ribosomal subunit rRNA binding
J5J84_RS11695	COG0450	alkyl hydroperoxide reductase
J5J84_RS11700	COG1960	acyl-CoA dehydrogenase activity
J5J84_RS11715	COG0123	including yeast histone deacetylase and acetoin utilization protein
J5J84_RS11720	COG2951	lytic endotransglycosylase activity
J5J84_RS11730	COG1596	polysaccharide export
J5J84_RS11730	COG1555	photosystem II stabilization
J5J84_RS11735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5J84_RS11740	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5J84_RS11745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J5J84_RS11765	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5J84_RS11770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5J84_RS11775	COG0287	Prephenate dehydrogenase
J5J84_RS11785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J5J84_RS11800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5J84_RS11820	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5J84_RS11830	COG4771	TonB-dependent receptor
J5J84_RS11845	COG0753	catalase activity
J5J84_RS11855	COG4335	DNA alkylation repair
J5J84_RS11865	COG0436	Aminotransferase
J5J84_RS11875	COG0251	oxidation-reduction process
J5J84_RS11880	COG1309	transcriptional regulator
J5J84_RS11935	COG0625	glutathione transferase activity
J5J84_RS11945	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J5J84_RS11950	COG1280	lysine exporter protein (LysE YggA)
J5J84_RS11970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5J84_RS11980	COG0784	Response regulator, receiver
J5J84_RS11980	COG2198	Histidine kinase
J5J84_RS11980	COG2205	protein histidine kinase activity
J5J84_RS11985	COG2046	Belongs to the sulfate adenylyltransferase family
J5J84_RS11990	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J5J84_RS11995	COG0642	Histidine kinase
J5J84_RS12005	COG0840	transmembrane signaling receptor activity
J5J84_RS12010	COG2119	membrane
J5J84_RS12025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J5J84_RS12030	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5J84_RS12045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J5J84_RS12050	COG2321	neutral zinc metallopeptidase
J5J84_RS12065	COG2175	clavaminate synthase activity
J5J84_RS12070	COG1846	Transcriptional regulator
J5J84_RS12075	COG0347	Belongs to the P(II) protein family
J5J84_RS12080	COG0004	ammonium transporteR
J5J84_RS12085	COG3909	cytochrome
J5J84_RS12095	COG0625	glutathione transferase activity
J5J84_RS12100	COG0730	response to heat
J5J84_RS12105	COG0482	sulfurtransferase activity
J5J84_RS12110	COG0277	FAD linked oxidase domain protein
J5J84_RS12115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5J84_RS12120	COG2879	small protein
J5J84_RS12125	COG1966	Carbon starvation protein
J5J84_RS12130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_RS12135	COG0765	amino acid transport
J5J84_RS12140	COG0765	amino acid transport
J5J84_RS12145	COG1126	abc transporter atp-binding protein
J5J84_RS12150	COG0028	Belongs to the TPP enzyme family
J5J84_RS12155	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_RS12160	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
J5J84_RS12165	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS12170	COG0596	Alpha beta hydrolase
J5J84_RS12170	COG2226	methyltransferase
J5J84_RS12170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5J84_RS12175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_RS12180	COG1116	anion transmembrane transporter activity
J5J84_RS12195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_RS12210	COG5285	phytanoyl-CoA dioxygenase
J5J84_RS12215	COG0662	Cupin 2, conserved barrel domain protein
J5J84_RS12225	COG0456	acetyltransferase
J5J84_RS12230	COG1846	Transcriptional regulator
J5J84_RS12240	COG0312	modulator of DNA gyrase
J5J84_RS12255	COG0308	aminopeptidase N
J5J84_RS12260	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J5J84_RS12275	COG0473	3-isopropylmalate dehydrogenase activity
J5J84_RS12285	COG0433	COG0433 Predicted ATPase
J5J84_RS12290	COG0217	transcriptional regulatory protein
J5J84_RS12295	COG0151	Belongs to the GarS family
J5J84_RS12305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5J84_RS12310	COG0799	negative regulation of ribosome biogenesis
J5J84_RS12315	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5J84_RS12320	COG0424	maF-like protein
J5J84_RS12340	COG0023	Translation Initiation Factor
J5J84_RS12350	COG2084	Dehydrogenase
J5J84_RS12355	COG0625	glutathione transferase activity
J5J84_RS12360	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5J84_RS12365	COG1047	Peptidyl-prolyl cis-trans
J5J84_RS12370	COG2003	Belongs to the UPF0758 family
J5J84_RS12375	COG1737	Transcriptional regulator
J5J84_RS12380	COG0477	Major facilitator Superfamily
J5J84_RS12390	COG2271	Major facilitator Superfamily
J5J84_RS12405	COG0534	Mate efflux family protein
J5J84_RS12410	COG4175	Glycine betaine
J5J84_RS12415	COG4176	ABC-type proline glycine betaine transport system permease component
J5J84_RS12425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J5J84_RS12430	COG2814	Major facilitator Superfamily
J5J84_RS12435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5J84_RS12440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J5J84_RS12445	COG0495	leucyl-tRNA aminoacylation
J5J84_RS12455	COG1466	dna polymerase III delta subunit
J5J84_RS12460	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J5J84_RS12465	COG1981	membrane
J5J84_RS12480	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J5J84_RS12490	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J5J84_RS12495	COG0148	phosphopyruvate hydratase activity
J5J84_RS12505	COG2814	Major facilitator Superfamily
J5J84_RS12520	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5J84_RS12530	COG0504	CTP synthase activity
J5J84_RS12565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J5J84_RS12575	COG0791	NLP P60 protein
J5J84_RS12585	COG0583	DNA-binding transcription factor activity
J5J84_RS12595	COG0583	DNA-binding transcription factor activity
J5J84_RS12605	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J5J84_RS12620	COG1045	serine acetyltransferase
J5J84_RS12635	COG1381	Involved in DNA repair and RecF pathway recombination
J5J84_RS12640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J5J84_RS12645	COG0571	ribonuclease III activity
J5J84_RS12660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5J84_RS12680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5J84_RS12685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5J84_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS12695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J5J84_RS12700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5J84_RS12710	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J5J84_RS12715	COG1399	metal-binding, possibly nucleic acid-binding protein
J5J84_RS12720	COG0424	maF-like protein
J5J84_RS12730	COG3023	N-Acetylmuramoyl-L-alanine amidase
J5J84_RS12735	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
J5J84_RS12740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J5J84_RS12745	COG0546	phosphoglycolate phosphatase activity
J5J84_RS12750	COG0564	pseudouridine synthase activity
J5J84_RS12755	COG1530	ribonuclease E activity
J5J84_RS12760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J5J84_RS12765	COG0159	tryptophan synthase activity
J5J84_RS12770	COG0133	tryptophan synthase activity
J5J84_RS12775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J5J84_RS12785	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J5J84_RS12790	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5J84_RS12800	COG2878	Part of a membrane complex involved in electron transport
J5J84_RS12805	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J5J84_RS12810	COG1129	ABC transporter
J5J84_RS12815	COG3047	cAMP biosynthetic process
J5J84_RS12840	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5J84_RS12845	COG2917	probably involved in intracellular septation
J5J84_RS12855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5J84_RS12860	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5J84_RS12870	COG1196	nuclear chromosome segregation
J5J84_RS12880	COG1573	uracil-dna glycosylase
J5J84_RS12885	COG1214	PFAM Peptidase M22, glycoprotease
J5J84_RS12900	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5J84_RS12905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5J84_RS12910	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5J84_RS12915	COG0560	Phosphoserine phosphatase
J5J84_RS12930	COG1007	ATP synthesis coupled electron transport
J5J84_RS12945	COG0713	ATP synthesis coupled electron transport
J5J84_RS12955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5J84_RS12960	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J5J84_RS12965	COG1034	ATP synthesis coupled electron transport
J5J84_RS12980	COG0649	NAD binding
J5J84_RS12985	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5J84_RS12990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5J84_RS12995	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5J84_RS13005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_RS13020	COG0149	triose-phosphate isomerase activity
J5J84_RS13025	COG0604	alcohol dehydrogenase
J5J84_RS13045	COG1185	polyribonucleotide nucleotidyltransferase activity
J5J84_RS13050	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5J84_RS13055	COG1183	phosphatidylcholine synthase activity
J5J84_RS13060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5J84_RS13065	COG0440	acetolactate synthase activity
J5J84_RS13070	COG0028	Belongs to the TPP enzyme family
J5J84_RS13075	COG1289	transmembrane transporter activity
J5J84_RS13080	COG3022	response to hydroperoxide
J5J84_RS13085	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS13095	COG3772	lysozyme
J5J84_RS13105	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5J84_RS13105	COG2755	lipolytic protein G-D-S-L family
J5J84_RS13230	COG3728	DNA packaging
J5J84_RS13360	COG0582	viral genome integration into host DNA
J5J84_RS13380	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5J84_RS13385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5J84_RS13390	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J5J84_RS13395	COG1674	ftsk spoiiie
J5J84_RS13400	COG0492	ferredoxin-NADP+ reductase activity
J5J84_RS13420	COG0477	Major facilitator Superfamily
J5J84_RS13440	COG2272	Belongs to the type-B carboxylesterase lipase family
J5J84_RS13445	COG1960	acyl-CoA dehydrogenase activity
J5J84_RS13470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5J84_RS13490	COG2204	response regulator
J5J84_RS13530	COG4964	Belongs to the GSP D family
J5J84_RS13595	COG0612	Peptidase, M16
J5J84_RS13600	COG0484	heat shock protein binding
J5J84_RS13605	COG0443	Heat shock 70 kDa protein
J5J84_RS13610	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5J84_RS13615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J5J84_RS13620	COG1420	regulation of RNA biosynthetic process
J5J84_RS13630	COG0497	DNA recombination
J5J84_RS13635	COG0735	belongs to the Fur family
J5J84_RS13640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5J84_RS13645	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5J84_RS13670	COG0477	Major facilitator Superfamily
J5J84_RS13680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J5J84_RS13710	COG1538	Outer membrane efflux protein
J5J84_RS13740	COG2814	Major facilitator Superfamily
J5J84_RS13750	COG2819	hydrolase of the alpha beta superfamily
J5J84_RS13770	COG1454	alcohol dehydrogenase
J5J84_RS13780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J5J84_RS13805	COG1414	Transcriptional regulator
J5J84_RS13810	COG0513	Belongs to the DEAD box helicase family
J5J84_RS13815	COG3657	addiction module killer protein
J5J84_RS13820	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J5J84_RS13825	COG0583	DNA-binding transcription factor activity
J5J84_RS13830	COG4638	Rieske (2fe-2S)
J5J84_RS13835	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
J5J84_RS13850	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5J84_RS13865	COG3971	2-oxopent-4-enoate hydratase activity
J5J84_RS13870	COG4569	acetaldehyde dehydrogenase (acetylating) activity
J5J84_RS13875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5J84_RS13880	COG2814	Major facilitator Superfamily
J5J84_RS13895	COG0154	amidase activity
J5J84_RS13900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_RS13905	COG2814	Major facilitator Superfamily
J5J84_RS13935	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS13945	COG0842	Transport permease protein
J5J84_RS13950	COG0842	Transport permease protein
J5J84_RS13950	COG1129	ABC transporter
J5J84_RS13955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5J84_RS13965	COG3243	poly(R)-hydroxyalkanoic acid synthase
J5J84_RS13975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J5J84_RS13980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5J84_RS13985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5J84_RS14000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5J84_RS14015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5J84_RS14020	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J5J84_RS14030	COG0789	Transcriptional regulator
J5J84_RS14040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5J84_RS14085	COG3278	Belongs to the heme-copper respiratory oxidase family
J5J84_RS14090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_RS14110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J5J84_RS14160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J5J84_RS14225	COG0517	IMP dehydrogenase activity
J5J84_RS14225	COG0516	GMP reductase activity
J5J84_RS14235	COG1027	Aspartate ammonia-lyase
J5J84_RS14240	COG1846	Transcriptional regulator
J5J84_RS14255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5J84_RS14260	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J5J84_RS14275	COG1414	Transcriptional regulator
J5J84_RS14295	COG0513	Belongs to the DEAD box helicase family
J5J84_RS14315	COG0429	hydrolase of the alpha beta-hydrolase fold
J5J84_RS14340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_RS14350	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J5J84_RS14360	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5J84_RS14365	COG0632	four-way junction helicase activity
J5J84_RS14375	COG2255	four-way junction helicase activity
J5J84_RS14385	COG0418	dihydroorotase activity
J5J84_RS14395	COG0415	Belongs to the DNA photolyase family
J5J84_RS14455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5J84_RS14460	COG4654	Cytochrome c, class I
J5J84_RS14500	COG1177	transmembrane transport
J5J84_RS14505	COG3842	ATPase activity
J5J84_RS14510	COG1840	ABC-type Fe3 transport system, periplasmic component
J5J84_RS14515	COG2084	Dehydrogenase
J5J84_RS14530	COG0494	nUDIX hydrolase
J5J84_RS14535	COG0442	prolyl-tRNA aminoacylation
J5J84_RS14540	COG0824	Thioesterase
J5J84_RS14545	COG0811	peptide transport
J5J84_RS14560	COG0823	Involved in the tonB-independent uptake of proteins
J5J84_RS14575	COG0596	Alpha beta hydrolase
J5J84_RS14600	COG1079	Belongs to the binding-protein-dependent transport system permease family
J5J84_RS14605	COG4603	Belongs to the binding-protein-dependent transport system permease family
J5J84_RS14610	COG3845	ABC transporter
J5J84_RS14630	COG0427	acetyl-CoA hydrolase
J5J84_RS14635	COG0583	DNA-binding transcription factor activity
J5J84_RS14640	COG3634	alkyl hydroperoxide reductase activity
J5J84_RS14655	COG0697	spore germination
J5J84_RS14660	COG0175	sulfate reduction
J5J84_RS14680	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_RS14685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_RS14690	COG5383	Protein conserved in bacteria
J5J84_RS14700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J5J84_RS14715	COG0583	DNA-binding transcription factor activity
J5J84_RS14720	COG1741	Belongs to the pirin family
J5J84_RS14725	COG3706	GGDEF domain
J5J84_RS14730	COG0154	amidase activity
J5J84_RS14740	COG3712	iron ion homeostasis
J5J84_RS14745	COG1595	DNA-templated transcription, initiation
J5J84_RS14755	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5J84_RS14765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J5J84_RS14770	COG0284	orotidine-5'-phosphate decarboxylase activity
J5J84_RS14790	COG1414	Transcriptional regulator
J5J84_RS14800	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J5J84_RS14810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5J84_RS14815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J5J84_RS14840	COG0742	ribosomal rna small subunit methyltransferase
J5J84_RS14845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J5J84_RS14850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J5J84_RS14880	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
J5J84_RS14905	COG1335	isochorismatase
J5J84_RS14910	COG2309	aminopeptidase activity
J5J84_RS14915	COG0596	Alpha beta hydrolase
J5J84_RS14920	COG2010	Cytochrome c
J5J84_RS14920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J5J84_RS14925	COG2080	2 iron, 2 sulfur cluster binding
J5J84_RS14930	COG2010	Cytochrome c
J5J84_RS14930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J5J84_RS14940	COG0410	ABC transporter
J5J84_RS14945	COG0411	ABC transporter
J5J84_RS14970	COG3706	GGDEF domain
J5J84_RS14985	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS15000	COG1234	tRNA 3'-trailer cleavage
J5J84_RS15005	COG2188	Transcriptional regulator
J5J84_RS15015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5J84_RS15025	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5J84_RS15025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5J84_RS15030	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J5J84_RS15030	COG3608	succinylglutamate desuccinylase aspartoacylase
J5J84_RS15035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_RS15045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_RS15075	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_RS15110	COG1335	isochorismatase
J5J84_RS15115	COG2309	aminopeptidase activity
J5J84_RS15120	COG0596	Alpha beta hydrolase
J5J84_RS15135	COG1120	ATPase activity
J5J84_RS15140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5J84_RS15150	COG4206	TonB-dependent receptor
J5J84_RS15155	COG2031	fatty acid transporter
J5J84_RS15160	COG0583	DNA-binding transcription factor activity
J5J84_RS15165	COG0402	S-adenosylhomocysteine deaminase activity
J5J84_RS15170	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS15190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5J84_RS15195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5J84_RS15200	COG0328	RNA-DNA hybrid ribonuclease activity
J5J84_RS15205	COG2226	methyltransferase
J5J84_RS15210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5J84_RS15215	COG1388	LysM domain
J5J84_RS15215	COG0741	lytic transglycosylase activity
J5J84_RS15235	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J5J84_RS15260	COG2204	response regulator
J5J84_RS15265	COG4191	Histidine kinase
J5J84_RS15270	COG1301	dicarboxylic acid transport
J5J84_RS15280	COG1054	Belongs to the UPF0176 family
J5J84_RS15305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5J84_RS15330	COG0604	alcohol dehydrogenase
J5J84_RS15360	COG1902	pentaerythritol trinitrate reductase activity
J5J84_RS15370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5J84_RS15375	COG1454	alcohol dehydrogenase
J5J84_RS15390	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
J5J84_RS15395	COG0583	DNA-binding transcription factor activity
J5J84_RS15420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_RS15435	COG1393	Belongs to the ArsC family
J5J84_RS15440	COG0431	NADPH-dependent FMN reductase
J5J84_RS15445	COG0745	RESPONSE REGULATOR receiver
J5J84_RS15450	COG0642	Histidine kinase
J5J84_RS15465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5J84_RS15465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5J84_RS15470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5J84_RS15475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5J84_RS15480	COG1881	PFAM PEBP family protein
J5J84_RS15485	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5J84_RS15490	COG0739	heme binding
J5J84_RS15495	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J5J84_RS15500	COG0316	Belongs to the HesB IscA family
J5J84_RS15510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5J84_RS15515	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5J84_RS15520	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5J84_RS15525	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_RS15530	COG0312	modulator of DNA gyrase
J5J84_RS15535	COG3028	Belongs to the UPF0307 family
J5J84_RS15560	COG0745	RESPONSE REGULATOR receiver
J5J84_RS15560	COG2205	protein histidine kinase activity
J5J84_RS15560	COG4191	Histidine kinase
J5J84_RS15565	COG4566	intracellular signal transduction
J5J84_RS15570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5J84_RS15600	COG0762	integral membrane protein
J5J84_RS15610	COG2169	Transcriptional regulator
J5J84_RS15610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5J84_RS15615	COG3133	Outer membrane lipoprotein
J5J84_RS15620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5J84_RS15635	COG0439	Biotin carboxylase
J5J84_RS15640	COG0511	ligase activity, forming carbon-carbon bonds
J5J84_RS15645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J5J84_RS15655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5J84_RS15660	COG3150	esterase
J5J84_RS15675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5J84_RS15680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5J84_RS15690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J5J84_RS15705	COG1678	Uncharacterized ACR, COG1678
J5J84_RS15720	COG0352	thiamine-phosphate diphosphorylase activity
J5J84_RS15725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5J84_RS15740	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J5J84_RS15750	COG3237	CsbD-like
J5J84_RS15755	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5J84_RS15760	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J5J84_RS15765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5J84_RS15770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5J84_RS15795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J5J84_RS15810	COG1126	abc transporter atp-binding protein
J5J84_RS15815	COG0765	amino acid transport
J5J84_RS15820	COG4597	amino acid ABC transporter
J5J84_RS15825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_RS15830	COG2884	Cell division ATP-binding protein ftsE
J5J84_RS15835	COG2177	Part of the ABC transporter FtsEX involved in
J5J84_RS15845	COG0772	Belongs to the SEDS family
J5J84_RS15850	COG0768	penicillin binding
J5J84_RS15860	COG1792	Involved in formation and maintenance of cell shape
J5J84_RS15865	COG1077	Cell shape determining protein MreB Mrl
J5J84_RS15870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5J84_RS15875	COG0154	amidase activity
J5J84_RS15880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5J84_RS15885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5J84_RS15890	COG0583	DNA-binding transcription factor activity
J5J84_RS15895	COG2259	Doxx family
J5J84_RS15900	COG3384	dioxygenase
J5J84_RS15910	COG3245	cytochrome
J5J84_RS15925	COG3604	Transcriptional regulator
J5J84_RS15940	COG0786	glutamate:sodium symporter activity
J5J84_RS15945	COG0142	geranyltranstransferase activity
J5J84_RS15955	COG0494	nUDIX hydrolase
J5J84_RS15960	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J5J84_RS15985	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J5J84_RS15990	COG0237	dephospho-CoA kinase activity
J5J84_RS16005	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5J84_RS16010	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J5J84_RS16020	COG0477	Major facilitator Superfamily
J5J84_RS16035	COG4206	TonB-dependent receptor
J5J84_RS16040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J5J84_RS16055	COG1595	DNA-templated transcription, initiation
J5J84_RS16065	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_RS16085	COG0598	Magnesium transport protein CorA
J5J84_RS16100	COG2022	thiamine diphosphate biosynthetic process
J5J84_RS16105	COG0351	phosphomethylpyrimidine kinase
J5J84_RS16110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J5J84_RS16115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J5J84_RS16120	COG1538	Outer membrane efflux protein
J5J84_RS16125	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5J84_RS16135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J5J84_RS16150	COG2226	methyltransferase
J5J84_RS16155	COG0745	RESPONSE REGULATOR receiver
J5J84_RS16170	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J5J84_RS16175	COG1984	allophanate hydrolase subunit 2
J5J84_RS16180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5J84_RS16185	COG1238	metal cluster binding
J5J84_RS16210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J5J84_RS16215	COG4988	ABC transporter
J5J84_RS16225	COG1294	oxidase, subunit
J5J84_RS16230	COG1271	oxidase subunit
J5J84_RS16245	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J5J84_RS16260	COG1137	ATPase activity
J5J84_RS16270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5J84_RS16275	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J5J84_RS16280	COG1660	Displays ATPase and GTPase activities
J5J84_RS16290	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5J84_RS16295	COG0792	nuclease activity
J5J84_RS16300	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J5J84_RS16315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5J84_RS16335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J5J84_RS16340	COG0793	Belongs to the peptidase S41A family
J5J84_RS16350	COG0588	phosphoglycerate mutase activity
J5J84_RS16355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J5J84_RS16365	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J5J84_RS16370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5J84_RS16375	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS16380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J5J84_RS16385	COG1040	competence protein
J5J84_RS16390	COG2226	methyltransferase
J5J84_RS16395	COG4771	TonB-dependent receptor
J5J84_RS16400	COG0745	RESPONSE REGULATOR receiver
J5J84_RS16405	COG2205	protein histidine kinase activity
J5J84_RS16415	COG2204	response regulator
J5J84_RS16430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J5J84_RS16430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5J84_RS16435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5J84_RS16445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5J84_RS16450	COG3473	Maleate cis-trans isomerase
J5J84_RS16465	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J5J84_RS16530	COG0438	transferase activity, transferring glycosyl groups
J5J84_RS16535	COG0500	methyltransferase
J5J84_RS16560	COG3328	transposase activity
J5J84_RS16565	COG1215	transferase activity, transferring glycosyl groups
J5J84_RS16575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5J84_RS16580	COG3307	-O-antigen
J5J84_RS16590	COG1088	dTDP-glucose 4,6-dehydratase activity
J5J84_RS16595	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J5J84_RS16615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5J84_RS16625	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5J84_RS16630	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5J84_RS16635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J5J84_RS16650	COG0356	it plays a direct role in the translocation of protons across the membrane
J5J84_RS16660	COG1024	Enoyl-CoA hydratase
J5J84_RS16675	COG0037	tRNA processing
J5J84_RS16680	COG0163	prenyltransferase activity
J5J84_RS16685	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J5J84_RS16690	COG2890	protein-(glutamine-N5) methyltransferase activity
J5J84_RS16715	COG3550	peptidyl-serine autophosphorylation
J5J84_RS16730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5J84_RS16735	COG2264	protein methyltransferase activity
J5J84_RS16740	COG4773	Receptor
J5J84_RS16760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5J84_RS16785	COG3180	Ammonia monooxygenase
J5J84_RS16805	COG5002	protein histidine kinase activity
J5J84_RS16820	COG0477	Major facilitator Superfamily
J5J84_RS16825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5J84_RS16850	COG1116	anion transmembrane transporter activity
J5J84_RS16880	COG0437	4 iron, 4 sulfur cluster binding
J5J84_RS16885	COG2864	formate dehydrogenase
J5J84_RS16895	COG1921	L-seryl-tRNASec selenium transferase activity
J5J84_RS16900	COG3276	selenocysteine insertion sequence binding
J5J84_RS16910	COG1476	TRANSCRIPTIONal
J5J84_RS16925	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS16945	COG0709	Synthesizes selenophosphate from selenide and ATP
J5J84_RS16960	COG0583	DNA-binding transcription factor activity
J5J84_RS16965	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
J5J84_RS16970	COG0348	domain, Protein
J5J84_RS16970	COG3901	Regulator of nitric oxide reductase transcription
J5J84_RS16975	COG4263	nitrous-oxide reductase activity
J5J84_RS16990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J5J84_RS17005	COG0166	Belongs to the GPI family
J5J84_RS17055	COG2233	PERMEase
J5J84_RS17060	COG0697	spore germination
J5J84_RS17065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_RS17070	COG0697	spore germination
J5J84_RS17090	COG2885	chlorophyll binding
J5J84_RS17185	COG0183	Belongs to the thiolase family
J5J84_RS17190	COG1024	Enoyl-CoA hydratase
J5J84_RS17190	COG1250	3-hydroxyacyl-CoA dehydrogenase
J5J84_RS17205	COG1127	ABC transporter
J5J84_RS17210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J5J84_RS17215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5J84_RS17230	COG1131	(ABC) transporter
J5J84_RS17235	COG0842	Transport permease protein
J5J84_RS17245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5J84_RS17255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5J84_RS17260	COG0131	Imidazoleglycerol-phosphate dehydratase
J5J84_RS17270	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J5J84_RS17275	COG0107	imidazoleglycerol-phosphate synthase activity
J5J84_RS17285	COG0140	phosphoribosyl-ATP diphosphatase activity
J5J84_RS17290	COG0537	adenosine 5'-monophosphoramidase activity
J5J84_RS17295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5J84_RS17300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5J84_RS17310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5J84_RS17320	COG1970	mechanosensitive ion channel activity
J5J84_RS17325	COG0723	plastoquinol--plastocyanin reductase activity
J5J84_RS17330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J5J84_RS17335	COG2857	Cytochrome c1
J5J84_RS17340	COG0625	glutathione transferase activity
J5J84_RS17345	COG2969	positive regulation of protein catabolic process
J5J84_RS17350	COG4208	sulfate ABC transporter
J5J84_RS17355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J5J84_RS17360	COG4150	thiosulfate binding
J5J84_RS17380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5J84_RS17400	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_RS17405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5J84_RS17415	COG2084	Dehydrogenase
J5J84_RS17420	COG0129	dihydroxy-acid dehydratase activity
J5J84_RS17425	COG1802	Transcriptional regulator
J5J84_RS17430	COG1522	sequence-specific DNA binding
J5J84_RS17440	COG3483	tryptophan 2,3-dioxygenase activity
J5J84_RS17460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5J84_RS17465	COG0656	L-ascorbic acid biosynthetic process
J5J84_RS17475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5J84_RS17480	COG3706	GGDEF domain
J5J84_RS17485	COG2226	methyltransferase
J5J84_RS17495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5J84_RS17510	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
J5J84_RS17515	COG0583	DNA-binding transcription factor activity
J5J84_RS17520	COG0477	Major facilitator Superfamily
J5J84_RS17525	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_RS17535	COG1335	isochorismatase
J5J84_RS17555	COG2823	Periplasmic or secreted lipoprotein
J5J84_RS17565	COG3284	Transcriptional regulator
J5J84_RS17595	COG1595	DNA-templated transcription, initiation
J5J84_RS17605	COG1522	sequence-specific DNA binding
J5J84_RS17615	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5J84_RS17635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J5J84_RS17675	COG0109	protoheme IX farnesyltransferase activity
J5J84_RS17695	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5J84_RS17715	COG3568	Endonuclease Exonuclease Phosphatase
J5J84_RS17720	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5J84_RS17745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_RS17755	COG1228	amidohydrolase
J5J84_RS17775	COG2986	histidine ammonia-lyase
J5J84_RS17780	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
J5J84_RS17810	COG2814	Major facilitator Superfamily
J5J84_RS17820	COG0789	Transcriptional regulator
J5J84_RS17850	COG0625	glutathione transferase activity
J5J84_RS17880	COG2365	Tyrosine phosphatase family
J5J84_RS17885	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5J84_RS17905	COG2423	ornithine cyclodeaminase activity
J5J84_RS17955	COG3069	C4-dicarboxylate transmembrane transporter activity
J5J84_RS17965	COG1802	Transcriptional regulator
J5J84_RS17975	COG2814	Major facilitator Superfamily
J5J84_RS17990	COG2814	Major facilitator Superfamily
J5J84_RS17995	COG0251	oxidation-reduction process
J5J84_RS18000	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_RS18005	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5J84_RS18010	COG2186	Transcriptional regulator
J5J84_RS18020	COG2814	Major facilitator Superfamily
J5J84_RS18030	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5J84_RS18035	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5J84_RS18040	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5J84_RS18060	COG5001	Diguanylate cyclase
J5J84_RS18060	COG5002	protein histidine kinase activity
J5J84_RS18070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5J84_RS18075	COG1333	cytochrome c biogenesis protein
J5J84_RS18085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J5J84_RS18090	COG0113	porphobilinogen synthase activity
J5J84_RS18095	COG4232	protein-disulfide reductase activity
J5J84_RS18115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5J84_RS18120	COG0203	ribosomal protein L17
J5J84_RS18125	COG0202	RNA polymerase activity
J5J84_RS18130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J5J84_RS18135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5J84_RS18140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5J84_RS18145	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5J84_RS18155	COG0201	protein transport
J5J84_RS18160	COG0200	Binds to the 23S rRNA
J5J84_RS18165	COG1841	ribosomal large subunit assembly
J5J84_RS18170	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J5J84_RS18175	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J5J84_RS18180	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5J84_RS18185	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J5J84_RS18190	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5J84_RS18195	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J5J84_RS18200	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5J84_RS18205	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5J84_RS18250	COG1538	Outer membrane efflux protein
J5J84_RS18265	COG1960	acyl-CoA dehydrogenase activity
J5J84_RS18270	COG0183	Belongs to the thiolase family
J5J84_RS18280	COG2067	long-chain fatty acid transport protein
J5J84_RS18295	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_RS18300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5J84_RS18305	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J5J84_RS18310	COG1648	precorrin-2 dehydrogenase activity
J5J84_RS18310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5J84_RS18325	COG1116	anion transmembrane transporter activity
J5J84_RS18345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5J84_RS18350	COG0255	Belongs to the universal ribosomal protein uL29 family
J5J84_RS18355	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J5J84_RS18360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5J84_RS18365	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5J84_RS18370	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5J84_RS18375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5J84_RS18380	COG0089	rRNA binding
J5J84_RS18385	COG0088	Forms part of the polypeptide exit tunnel
J5J84_RS18390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5J84_RS18395	COG4175	Glycine betaine
J5J84_RS18400	COG4176	ABC-type proline glycine betaine transport system permease component
J5J84_RS18405	COG0051	transcription antitermination factor activity, RNA binding
J5J84_RS18410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5J84_RS18415	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5J84_RS18420	COG0049	tRNA binding
J5J84_RS18425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J5J84_RS18455	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
J5J84_RS18460	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5J84_RS18465	COG0085	RNA polymerase activity
J5J84_RS18470	COG0222	ribosome binding
J5J84_RS18475	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5J84_RS18480	COG0081	regulation of translation
J5J84_RS18505	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5J84_RS18525	COG1475	DNA binding
J5J84_RS18530	COG1192	Involved in chromosome partitioning
J5J84_RS18535	COG0357	Ribosomal RNA small subunit methyltransferase G
J5J84_RS18540	COG0445	tRNA wobble uridine modification
J5J84_RS18545	COG0436	Aminotransferase
J5J84_RS18555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J5J84_RS18565	COG3706	GGDEF domain
J5J84_RS18570	COG0688	phosphatidylethanolamine metabolic process
J5J84_RS18580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5J84_RS18625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5J84_RS18660	COG0753	catalase activity
J5J84_RS18665	COG0706	membrane insertase activity
J5J84_RS18670	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5J84_RS18675	COG0594	ribonuclease P activity
J5J84_RS18680	COG0230	Belongs to the bacterial ribosomal protein bL34 family